CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 PIRSF PIRSF011572 1 257 1.0E-122 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 Pfam PF06018 CodY GAF-like domain 2 178 3.2E-81 T 29-03-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 Gene3D G3DSA:3.30.450.40 1 159 4.7E-30 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 Pfam PF08222 CodY helix-turn-helix domain 197 257 1.5E-38 T 29-03-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 5.4E-124 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 149.326 T 29-03-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 Gene3D G3DSA:1.10.10.10 160 259 1.7E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08635 81ca06db1c987b799413bd48e3f5bc5b 259 SUPERFAMILY SSF46785 167 256 1.4E-42 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 Gene3D G3DSA:3.40.50.880 175 364 3.1E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 Pfam PF00117 Glutamine amidotransferase class-I 173 349 3.6E-48 T 29-03-2018 IPR017926 Glutamine amidotransferase CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 SUPERFAMILY SSF52317 140 354 8.25E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00097 Anthranilate synthase component II signature 213 222 6.0E-7 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00097 Anthranilate synthase component II signature 326 339 6.0E-7 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00097 Anthranilate synthase component II signature 240 251 6.0E-7 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 240 251 8.0E-12 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 8.0E-12 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00096 Glutamine amidotransferase superfamily signature 326 339 8.0E-12 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 SMART SM01097 1 131 5.0E-89 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 1.4E-37 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 282 293 1.4E-37 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 240 256 1.4E-37 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 257 274 1.4E-37 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 1.4E-37 T 29-03-2018 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 3.0E-52 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 352 2.3E-148 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 Gene3D G3DSA:3.50.30.20 1 148 2.6E-58 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 355 49.045 T 29-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08320 034b277043a541f3b7de25676ec3fdc1 365 SUPERFAMILY SSF52021 1 145 1.02E-57 T 29-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS17010 76096b6312e6b214d2da152efdbd025d 90 Pfam PF06013 Proteins of 100 residues with WXG 3 88 1.1E-22 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS17010 76096b6312e6b214d2da152efdbd025d 90 SUPERFAMILY SSF158414 5 79 1.11E-22 T 29-03-2018 IPR029013 HP0062-like domain CSW12_RS17010 76096b6312e6b214d2da152efdbd025d 90 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 4.2E-27 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS17010 76096b6312e6b214d2da152efdbd025d 90 Gene3D G3DSA:1.10.287.850 1 90 1.2E-18 T 29-03-2018 CSW12_RS11635 a6b584b8e2517a819e938007532f7b75 156 SUPERFAMILY SSF109854 19 151 7.69E-17 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS11635 a6b584b8e2517a819e938007532f7b75 156 Pfam PF12867 DinB superfamily 25 126 1.9E-9 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS11635 a6b584b8e2517a819e938007532f7b75 156 Gene3D G3DSA:1.20.120.450 3 156 1.9E-18 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 SUPERFAMILY SSF49503 124 289 4.52E-43 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 210 227 1.2E-14 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 192 209 1.2E-14 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 116 1.2E-14 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 172 192 1.2E-14 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 PRINTS PR01166 Cytochrome c oxidase subunit II signature 84 96 1.2E-14 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 Gene3D G3DSA:1.10.287.90 27 113 1.8E-22 T 29-03-2018 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 SUPERFAMILY SSF81464 14 116 5.72E-21 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 107 3.7E-10 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 31 237 5.1E-55 T 29-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 150 227 1.8E-15 T 29-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 Gene3D G3DSA:2.60.40.420 116 262 3.2E-42 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 SUPERFAMILY SSF46626 249 346 1.07E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 Gene3D G3DSA:1.10.760.10 263 349 9.3E-18 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS08030 299ec4f23fc2823c2169d2a4b93aa948 349 Pfam PF00034 Cytochrome c 254 346 1.9E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS21565 40b542ea86bc1f95c9ca4634015be227 137 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 137 25.859 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CSW12_RS21565 40b542ea86bc1f95c9ca4634015be227 137 SMART SM00732 1 103 6.4E-42 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CSW12_RS21565 40b542ea86bc1f95c9ca4634015be227 137 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 2.0E-52 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CSW12_RS21565 40b542ea86bc1f95c9ca4634015be227 137 Pfam PF03652 Holliday junction resolvase 1 136 1.4E-47 T 29-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CSW12_RS21565 40b542ea86bc1f95c9ca4634015be227 137 Gene3D G3DSA:3.30.420.140 1 137 1.8E-49 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CSW12_RS21565 40b542ea86bc1f95c9ca4634015be227 137 SUPERFAMILY SSF53098 1 136 5.61E-47 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS22915 a098148247c5209fd6ab7315c012f004 391 SUPERFAMILY SSF53383 26 386 1.48E-117 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS22915 a098148247c5209fd6ab7315c012f004 391 PIRSF PIRSF001434 1 387 2.6E-143 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS22915 a098148247c5209fd6ab7315c012f004 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 384 6.4E-141 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS22915 a098148247c5209fd6ab7315c012f004 391 Gene3D G3DSA:3.90.1150.10 259 391 9.0E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS22915 a098148247c5209fd6ab7315c012f004 391 TIGRFAM TIGR01328 met_gam_lyase: methionine gamma-lyase 4 385 3.2E-167 T 29-03-2018 IPR006237 L-methionine gamma-lyase GO:0018826 KEGG: 00270+4.4.1.11|KEGG: 00450+4.4.1.11|KEGG: 00920+4.4.1.2|MetaCyc: PWY-7793 CSW12_RS22915 a098148247c5209fd6ab7315c012f004 391 Gene3D G3DSA:3.40.640.10 4 257 6.0E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 SMART SM00345 17 76 3.6E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 SUPERFAMILY SSF46785 7 84 8.44E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 SUPERFAMILY SSF53383 109 478 1.79E-85 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 Gene3D G3DSA:3.90.1150.10 359 480 5.8E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 9.5E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 Gene3D G3DSA:1.10.10.10 3 78 5.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 Pfam PF00155 Aminotransferase class I and II 146 469 1.7E-27 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS14685 8b0a7161610815f7c547b849242af709 482 Gene3D G3DSA:3.40.640.10 145 358 8.8E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS21635 c409f0255969603bbc1a911a5410c0d2 213 Gene3D G3DSA:1.10.10.60 1 100 2.4E-6 T 29-03-2018 CSW12_RS21635 c409f0255969603bbc1a911a5410c0d2 213 Pfam PF13921 Myb-like DNA-binding domain 8 62 6.5E-6 T 29-03-2018 CSW12_RS21635 c409f0255969603bbc1a911a5410c0d2 213 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 81 4.1E-45 T 29-03-2018 IPR014243 Transcription factor, RsfA CSW12_RS21635 c409f0255969603bbc1a911a5410c0d2 213 Gene3D G3DSA:1.20.5.400 104 182 2.6E-6 T 29-03-2018 CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 SUPERFAMILY SSF53098 85 219 1.09E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 SUPERFAMILY SSF55658 3 48 3.56E-14 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 PIRSF PIRSF037839 1 92 6.4E-14 T 29-03-2018 IPR017290 Ribonuclease H, Bacteroides-type GO:0004523 CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 PIRSF PIRSF037839 153 208 680.0 T 29-03-2018 IPR017290 Ribonuclease H, Bacteroides-type GO:0004523 CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 PIRSF PIRSF037839 61 130 310.0 T 29-03-2018 IPR017290 Ribonuclease H, Bacteroides-type GO:0004523 CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 Gene3D G3DSA:3.40.970.10 1 52 1.7E-21 T 29-03-2018 IPR011320 Ribonuclease H1, N-terminal CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 Gene3D G3DSA:3.30.420.10 60 220 2.6E-26 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 Pfam PF01693 Caulimovirus viroplasmin 4 47 9.8E-19 T 29-03-2018 IPR011320 Ribonuclease H1, N-terminal CSW12_RS31085 885d2abc03e51ff641452098f7381fe2 220 Pfam PF00075 RNase H 84 217 1.2E-14 T 29-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CSW12_RS20090 81d3e7dd146dd39cd789193c54321f35 88 Pfam PF09360 Iron-binding zinc finger CDGSH type 31 75 1.0E-16 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CSW12_RS20090 81d3e7dd146dd39cd789193c54321f35 88 PIRSF PIRSF037158 1 88 4.5E-61 T 29-03-2018 IPR017122 Uncharacterised conserved protein UCP037158 CSW12_RS20090 81d3e7dd146dd39cd789193c54321f35 88 SMART SM00704 35 80 0.0016 T 29-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 Pfam PF13527 Acetyltransferase (GNAT) domain 10 132 7.2E-36 T 29-03-2018 CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 Pfam PF13530 Sterol carrier protein domain 180 387 1.0E-51 T 29-03-2018 IPR025559 Enhanced intracellular survival protein domain CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 Gene3D G3DSA:3.40.630.30 148 278 2.2E-43 T 29-03-2018 CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 SUPERFAMILY SSF55718 286 391 6.28E-26 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 Gene3D G3DSA:3.30.1050.10 279 385 6.6E-23 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 Gene3D G3DSA:3.40.630.30 2 147 1.2E-13 T 29-03-2018 CSW12_RS12930 6b2ecf8949e3e546dd74e8591cb65b9a 391 SUPERFAMILY SSF55729 6 285 3.99E-72 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 SUPERFAMILY SSF48557 37 470 6.13E-93 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 Pfam PF14698 Argininosuccinate lyase C-terminal 375 447 4.0E-13 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 Gene3D G3DSA:1.10.275.10 26 115 2.9E-11 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 TIGRFAM TIGR00838 argH: argininosuccinate lyase 33 472 2.1E-97 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 Pfam PF00206 Lyase 96 308 3.8E-42 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 5.5E-18 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 5.5E-18 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 5.5E-18 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 5.5E-18 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 1.9E-27 T 29-03-2018 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 1.9E-27 T 29-03-2018 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 1.9E-27 T 29-03-2018 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 1.9E-27 T 29-03-2018 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 1.9E-27 T 29-03-2018 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 Gene3D G3DSA:1.20.200.10 116 384 2.0E-60 T 29-03-2018 CSW12_RS10015 1150fc49dee3682c7e0674dba88aa344 503 Gene3D G3DSA:1.10.40.30 385 449 9.0E-14 T 29-03-2018 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 PIRSF PIRSF039102 1 356 4.1E-116 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 290 318 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 Gene3D G3DSA:3.30.470.20 211 357 9.3E-45 T 29-03-2018 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 SUPERFAMILY SSF52440 3 134 8.82E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 Gene3D G3DSA:3.30.1490.20 150 210 4.1E-22 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 Pfam PF07478 D-ala D-ala ligase C-terminus 143 344 4.6E-79 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 Gene3D G3DSA:3.40.50.20 1 145 2.7E-45 T 29-03-2018 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 SUPERFAMILY SSF56059 135 351 7.6E-61 T 29-03-2018 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 347 1.6E-114 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 348 41.449 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28660 f8dc66a63e631311702ebce9be46862a 361 Pfam PF01820 D-ala D-ala ligase N-terminus 5 124 5.7E-31 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS20565 55b514c77def0909a10b7f6e6fa19fc1 192 SUPERFAMILY SSF55729 3 138 7.19E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS20565 55b514c77def0909a10b7f6e6fa19fc1 192 Pfam PF13302 Acetyltransferase (GNAT) domain 4 138 4.2E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS20565 55b514c77def0909a10b7f6e6fa19fc1 192 Gene3D G3DSA:3.40.630.30 33 176 5.5E-10 T 29-03-2018 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 349 368 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 272 288 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 311 330 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 332 348 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 105 118 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 14 34 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01272 Acetoin utilisation ACUC protein signature 84 98 1.3E-42 T 29-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 SUPERFAMILY SSF52768 3 366 4.36E-107 T 29-03-2018 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 Gene3D G3DSA:3.40.800.20 1 354 3.4E-94 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01270 Histone deacetylase superfamily signature 247 257 6.5E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01270 Histone deacetylase superfamily signature 128 151 6.5E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 PRINTS PR01270 Histone deacetylase superfamily signature 161 176 6.5E-17 T 29-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CSW12_RS22985 4d132c9c9f5cc029e80ac36d854a7d5f 388 Pfam PF00850 Histone deacetylase domain 20 314 2.3E-77 T 29-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 SUPERFAMILY SSF53474 37 392 2.93E-83 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 374 573 1.7E-30 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 71 350 9.0E-75 T 29-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 Gene3D G3DSA:3.40.50.1820 36 390 2.4E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 SUPERFAMILY SSF49785 437 578 2.34E-37 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 91 107 3.4E-6 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 57 67 3.4E-6 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 75 84 3.4E-6 T 29-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 Gene3D G3DSA:2.60.120.260 391 578 1.2E-31 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS13390 1c3b8ea84c230e3747e926f8ba12a3af 579 SMART SM00939 362 576 6.9E-41 T 29-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CSW12_RS06085 3f6af98953374eccd58066f7755033a8 266 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 14 251 1.2E-92 T 29-03-2018 IPR022493 Integral membrane YkoY CSW12_RS06085 3f6af98953374eccd58066f7755033a8 266 SUPERFAMILY SSF103473 13 248 1.44E-7 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS06085 3f6af98953374eccd58066f7755033a8 266 Pfam PF03741 Integral membrane protein TerC family 18 210 4.8E-52 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CSW12_RS06085 3f6af98953374eccd58066f7755033a8 266 Gene3D G3DSA:1.20.1250.20 5 115 0.0015 T 29-03-2018 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 Gene3D G3DSA:1.10.287.130 345 409 1.5E-9 T 29-03-2018 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 SMART SM00387 469 580 1.3E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 SUPERFAMILY SSF47384 350 423 7.46E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 534 3.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 558 3.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 520 3.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 577 3.5E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 SUPERFAMILY SSF55874 412 578 5.5E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 Gene3D G3DSA:3.30.565.10 410 580 2.0E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 578 1.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 414 1.3E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS04855 7774dc68b4623bc64bbb265cac47e756 580 SMART SM00388 355 423 4.3E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS07675 5c5d430f0e2f95a8a3be9b75551b24d4 280 SUPERFAMILY SSF161098 6 280 6.26E-70 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS07675 5c5d430f0e2f95a8a3be9b75551b24d4 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 273 3.0E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS07675 5c5d430f0e2f95a8a3be9b75551b24d4 280 Gene3D G3DSA:1.10.3720.10 1 267 4.4E-47 T 29-03-2018 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 Pfam PF01016 Ribosomal L27 protein 10 89 5.4E-34 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 Gene3D G3DSA:2.40.50.100 28 92 6.6E-28 T 29-03-2018 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 5.0E-17 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.7E-39 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 SUPERFAMILY SSF110324 10 91 1.6E-31 T 29-03-2018 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 1.8E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 1.8E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 1.8E-37 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.561 T 29-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21845 b64a514b5f6a2a0cda12989078f57a28 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 29-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 Pfam PF00270 DEAD/DEAH box helicase 28 196 2.0E-42 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 SMART SM00487 23 224 1.3E-53 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 Pfam PF00271 Helicase conserved C-terminal domain 233 341 7.0E-25 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 436 50.728 T 29-03-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 Gene3D G3DSA:3.40.50.300 3 223 3.9E-52 T 29-03-2018 CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 Gene3D G3DSA:3.40.50.300 224 436 9.6E-42 T 29-03-2018 CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 SUPERFAMILY SSF52540 73 360 1.63E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21040 70c46535497aca2da27fdd0dcece5e98 436 SMART SM00490 260 341 6.0E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS16695 d003b74b89f5dd57bc7b37b5b9a04cdc 210 SUPERFAMILY SSF46785 117 201 5.79E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16695 d003b74b89f5dd57bc7b37b5b9a04cdc 210 Pfam PF13730 Helix-turn-helix domain 94 145 1.4E-6 T 29-03-2018 CSW12_RS16695 d003b74b89f5dd57bc7b37b5b9a04cdc 210 Gene3D G3DSA:1.10.10.10 71 208 3.9E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 SUPERFAMILY SSF47648 1 69 1.44E-24 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 Gene3D G3DSA:1.20.970.10 1 66 5.6E-28 T 29-03-2018 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 5.5E-186 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 SUPERFAMILY SSF54680 331 431 1.44E-29 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 SUPERFAMILY SSF52418 69 329 1.44E-92 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.6E-24 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 Gene3D G3DSA:3.40.1030.10 68 337 5.7E-94 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 7.2E-27 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 Gene3D G3DSA:3.90.1170.30 338 423 3.9E-28 T 29-03-2018 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 305 2.8E-48 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 SMART SM00941 345 418 2.3E-30 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 PIRSF PIRSF000478 1 432 1.2E-170 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS18360 b5059e26bd2bbd393faecdcb154c1bb2 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS21070 1271be14715514102c560266c26f5747 375 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 335 361 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 166 179 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Pfam PF00140 Sigma-70 factor, region 1.2 104 137 8.4E-18 T 29-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Pfam PF03979 Sigma-70 factor, region 1.1 17 81 5.4E-16 T 29-03-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CSW12_RS21070 1271be14715514102c560266c26f5747 375 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 138 374 1.1E-124 T 29-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 SUPERFAMILY SSF88946 103 212 1.96E-54 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 363 3.2E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 11 375 34.044 T 29-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 SUPERFAMILY SSF88659 215 288 2.43E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 314 326 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 190 198 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 335 350 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 166 179 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 PRINTS PR00046 Major sigma-70 factor signature 350 361 3.2E-32 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Pfam PF04545 Sigma-70, region 4 310 363 5.2E-20 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.601.10 1 211 5.3E-78 T 29-03-2018 CSW12_RS21070 1271be14715514102c560266c26f5747 375 SUPERFAMILY SSF88659 272 373 4.11E-30 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.10.10 212 262 3.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21070 1271be14715514102c560266c26f5747 375 Gene3D G3DSA:1.10.10.10 304 375 6.6E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21070 1271be14715514102c560266c26f5747 375 Pfam PF04542 Sigma-70 region 2 142 211 3.7E-22 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21070 1271be14715514102c560266c26f5747 375 Pfam PF04539 Sigma-70 region 3 221 297 1.4E-31 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 Gene3D G3DSA:3.30.479.20 156 290 2.1E-51 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 Gene3D G3DSA:3.30.479.20 57 155 1.1E-21 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 SUPERFAMILY SSF46934 1 55 1.1E-21 T 29-03-2018 IPR009060 UBA-like GO:0005515 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 1.6E-118 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 Gene3D G3DSA:1.10.8.10 1 55 5.1E-26 T 29-03-2018 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 Pfam PF00889 Elongation factor TS 70 274 7.1E-75 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 SUPERFAMILY SSF54713 55 144 3.6E-21 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 29-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 SUPERFAMILY SSF54713 151 293 2.62E-52 T 29-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS08645 ec4d80ae325208b52edf578ec5e14fe3 295 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.804 T 29-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 472 8.3E-182 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 Gene3D G3DSA:1.10.10.410 412 473 2.2E-23 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 SUPERFAMILY SSF55931 4 293 1.11E-121 T 29-03-2018 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 SUPERFAMILY SSF89095 294 400 8.2E-36 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 Pfam PF02934 GatB/GatE catalytic domain 6 285 3.5E-112 T 29-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 141 155 - T 29-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 Pfam PF02637 GatB domain 325 472 6.6E-56 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 SMART SM00845 325 472 6.0E-77 T 29-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CSW12_RS00430 bb977c461ee29e9251269488469a15c9 475 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 473 39.034 T 29-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 Pfam PF03466 LysR substrate binding domain 90 290 2.9E-39 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS19140 9140267c205134131df529bf46468bb2 297 Gene3D G3DSA:3.40.190.10 92 179 5.3E-17 T 29-03-2018 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 SUPERFAMILY SSF53850 90 295 2.78E-38 T 29-03-2018 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 Gene3D G3DSA:3.40.190.10 180 266 3.5E-18 T 29-03-2018 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 Gene3D G3DSA:1.10.10.10 1 91 4.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19140 9140267c205134131df529bf46468bb2 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.2E-12 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 SUPERFAMILY SSF46785 2 111 8.49E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19140 9140267c205134131df529bf46468bb2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS19140 9140267c205134131df529bf46468bb2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS03860 1d2fe24525da11e4932cf15b19cd3d60 273 SMART SM00849 25 207 2.1E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS03860 1d2fe24525da11e4932cf15b19cd3d60 273 Gene3D G3DSA:3.60.15.10 5 266 3.7E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS03860 1d2fe24525da11e4932cf15b19cd3d60 273 SUPERFAMILY SSF56281 24 229 9.43E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12730 f41ab1c7a6902df0dc4f0f1d080bc106 546 Pfam PF01546 Peptidase family M20/M25/M40 109 438 1.4E-11 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS12730 f41ab1c7a6902df0dc4f0f1d080bc106 546 PIRSF PIRSF010386 1 545 6.0E-240 T 29-03-2018 IPR012166 Uncharacterised protein family RocB CSW12_RS12730 f41ab1c7a6902df0dc4f0f1d080bc106 546 Gene3D G3DSA:3.40.630.10 3 541 6.5E-32 T 29-03-2018 CSW12_RS12730 f41ab1c7a6902df0dc4f0f1d080bc106 546 SUPERFAMILY SSF53187 6 230 6.02E-33 T 29-03-2018 CSW12_RS12730 f41ab1c7a6902df0dc4f0f1d080bc106 546 SUPERFAMILY SSF53187 480 530 6.02E-33 T 29-03-2018 CSW12_RS11310 4b38061f4d1dcd46f860035616a9d85e 231 Pfam PF00881 Nitroreductase family 22 209 8.4E-28 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS11310 4b38061f4d1dcd46f860035616a9d85e 231 SUPERFAMILY SSF55469 16 229 2.36E-55 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS11310 4b38061f4d1dcd46f860035616a9d85e 231 Gene3D G3DSA:3.40.109.10 9 231 7.9E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Pfam PF01043 SecA preprotein cross-linking domain 230 338 7.5E-42 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SMART SM00958 226 338 3.9E-66 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 499 3.3E-244 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Pfam PF00271 Helicase conserved C-terminal domain 419 529 5.9E-6 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SUPERFAMILY SSF52540 397 568 6.99E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Gene3D G3DSA:3.40.50.300 8 267 7.4E-57 T 29-03-2018 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Gene3D G3DSA:3.40.50.300 289 396 1.9E-8 T 29-03-2018 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 779 19.755 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SUPERFAMILY SSF81886 570 823 4.71E-80 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 99 113 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 115 125 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 168 188 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 393 406 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 61 85 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 319 341 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 PRINTS PR00906 SecA protein signature 356 373 2.2E-73 T 29-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SUPERFAMILY SSF81767 225 348 2.49E-48 T 29-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Gene3D G3DSA:1.10.3060.10 584 687 4.7E-30 T 29-03-2018 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Gene3D G3DSA:1.10.3060.10 688 788 1.4E-26 T 29-03-2018 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 ProSitePatterns PS01312 SecA family signature. 480 495 - T 29-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Pfam PF07517 SecA DEAD-like domain 6 382 1.2E-130 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SMART SM00957 5 382 5.3E-289 T 29-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SUPERFAMILY SSF52540 348 395 3.16E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 SUPERFAMILY SSF52540 5 226 3.16E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Pfam PF07516 SecA Wing and Scaffold domain 567 776 2.1E-64 T 29-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Pfam PF02810 SEC-C motif 815 832 4.6E-8 T 29-03-2018 IPR004027 SEC-C motif CSW12_RS25635 4bce1b4e752436c3ad6a40d321f17ea9 835 Gene3D G3DSA:3.40.50.300 397 583 8.5E-55 T 29-03-2018 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 SUPERFAMILY SSF100950 2 342 5.11E-114 T 29-03-2018 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 37.387 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 Gene3D G3DSA:1.20.120.420 9 146 1.6E-47 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 Gene3D G3DSA:3.40.50.10470 147 353 2.8E-62 T 29-03-2018 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 36 336 1.5E-121 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 Pfam PF01008 Initiation factor 2 subunit family 49 335 2.5E-85 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CSW12_RS07525 1cfd6b676cf6b1ef1e45e8db01c2c007 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 4.4E-139 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 SUPERFAMILY SSF47364 18 96 3.01E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 5.9E-119 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 5.4E-82 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 SMART SM00963 22 103 3.4E-25 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 65.112 T 29-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 SMART SM00962 120 321 1.4E-123 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 Pfam PF02881 SRP54-type protein, helical bundle domain 34 99 9.3E-15 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 Gene3D G3DSA:3.40.50.300 112 322 3.9E-44 T 29-03-2018 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 Gene3D G3DSA:1.20.120.140 11 100 1.1E-22 T 29-03-2018 CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 SUPERFAMILY SSF52540 117 319 1.13E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08540 c3b8a3a4e64fddeb478639b4364081d4 329 SMART SM00382 119 297 3.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 179 2.8E-37 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 Gene3D G3DSA:3.40.50.970 355 551 5.7E-33 T 29-03-2018 CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 SUPERFAMILY SSF52518 5 182 7.21E-47 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 Gene3D G3DSA:3.40.50.970 1 195 1.2E-52 T 29-03-2018 CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 PIRSF PIRSF036565 1 558 9.8E-222 T 29-03-2018 IPR012110 Thiamine pyrophosphate (TPP)-dependent enzyme GO:0016831 CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 SUPERFAMILY SSF52518 365 553 2.86E-41 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 SUPERFAMILY SSF52467 166 339 3.51E-38 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 314 6.4E-30 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 Gene3D G3DSA:3.40.50.1220 196 347 1.5E-29 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS15670 6bbb81b5e1183ae5f850696c8ec0a1e6 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 401 535 1.4E-17 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS11660 fab795a4f93b4efb359dee3d7fba33a5 380 Gene3D G3DSA:1.20.120.330 182 276 2.9E-7 T 29-03-2018 CSW12_RS11660 fab795a4f93b4efb359dee3d7fba33a5 380 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 343 375 2.7E-4 T 29-03-2018 CSW12_RS11660 fab795a4f93b4efb359dee3d7fba33a5 380 Gene3D G3DSA:3.90.20.10 23 181 7.5E-9 T 29-03-2018 CSW12_RS11660 fab795a4f93b4efb359dee3d7fba33a5 380 Gene3D G3DSA:1.10.1660.10 277 336 0.13 T 29-03-2018 CSW12_RS07940 85a99539be93a97416a199a15de4b6cd 89 PIRSF PIRSF037260 1 89 1.2E-39 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CSW12_RS07940 85a99539be93a97416a199a15de4b6cd 89 Gene3D G3DSA:1.10.220.80 12 89 6.3E-32 T 29-03-2018 IPR023324 BH2638-like domain CSW12_RS07940 85a99539be93a97416a199a15de4b6cd 89 SUPERFAMILY SSF158504 4 86 1.96E-34 T 29-03-2018 IPR023324 BH2638-like domain CSW12_RS07940 85a99539be93a97416a199a15de4b6cd 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 86 2.0E-41 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CSW12_RS07940 85a99539be93a97416a199a15de4b6cd 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 86 1.5E-37 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CSW12_RS07940 85a99539be93a97416a199a15de4b6cd 89 Hamap MF_01041 UPF0223 protein . 1 88 26.992 T 29-03-2018 IPR007920 Protein of unknown function UPF0223 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Gene3D G3DSA:3.10.50.10 351 424 8.8E-19 T 29-03-2018 IPR029070 Chitinase insertion domain CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SMART SM00060 485 557 1.3E-13 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Gene3D G3DSA:2.60.40.10 478 574 2.2E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SUPERFAMILY SSF54556 339 421 1.31E-22 T 29-03-2018 IPR029070 Chitinase insertion domain CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SUPERFAMILY SSF49384 574 670 1.46E-24 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SMART SM00637 579 672 3.0E-33 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Gene3D G3DSA:3.20.20.80 38 350 5.0E-89 T 29-03-2018 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 ProSitePatterns PS01095 Chitinases family 18 active site. 201 209 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SMART SM00636 39 450 8.9E-162 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Pfam PF00704 Glycosyl hydrolases family 18 40 450 6.1E-100 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SUPERFAMILY SSF49265 481 561 8.66E-16 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Gene3D G3DSA:2.60.40.290 575 672 2.1E-23 T 29-03-2018 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Pfam PF00041 Fibronectin type III domain 488 559 4.9E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 Pfam PF00553 Cellulose binding domain 580 662 8.2E-20 T 29-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SUPERFAMILY SSF51445 422 451 8.33E-102 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS00820 eeba12a7ba991320c3c67b83267dc5b6 674 SUPERFAMILY SSF51445 34 339 8.33E-102 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.30.70.20 109 156 0.055 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 SMART SM00929 85 126 4.4E-13 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 PIRSF PIRSF036643 1 968 0.0 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 SUPERFAMILY SSF53706 255 775 1.01E-193 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 263 315 2.0E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.40.228.10 421 505 1.9E-17 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:2.40.40.20 788 936 9.1E-24 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.10.20.30 1 108 3.4E-9 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 8.0E-251 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.40.50.740 510 787 9.6E-78 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 SUPERFAMILY SSF54292 6 128 3.82E-28 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 1.4E-10 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 2.4E-20 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 SUPERFAMILY SSF50692 797 935 1.31E-33 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.40.50.740 318 420 5.3E-23 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 266 283 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.30.70.20 157 200 6.4E-11 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:2.20.25.90 274 316 2.2E-17 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 SMART SM00926 261 315 6.8E-17 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 78 2.4E-12 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF00384 Molybdopterin oxidoreductase 318 741 2.1E-81 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 SUPERFAMILY SSF54862 136 218 1.15E-16 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Gene3D G3DSA:3.30.70.20 201 273 0.0024 T 29-03-2018 CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF00037 4Fe-4S binding domain 145 162 4.8E-5 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS01665 7a7d07fd2bc505f31cb15b67baaec6b6 978 Pfam PF00037 4Fe-4S binding domain 188 209 9.7E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS16555 14f58c830539b22bb36ae18ce449da8a 608 Pfam PF07728 AAA domain (dynein-related subfamily) 284 436 4.3E-7 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CSW12_RS16555 14f58c830539b22bb36ae18ce449da8a 608 Gene3D G3DSA:3.40.50.300 209 443 1.1E-14 T 29-03-2018 CSW12_RS16555 14f58c830539b22bb36ae18ce449da8a 608 SUPERFAMILY SSF52540 280 447 5.4E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Gene3D G3DSA:2.40.110.10 146 240 4.5E-31 T 29-03-2018 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Gene3D G3DSA:1.10.540.10 1 145 1.7E-33 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Gene3D G3DSA:1.20.140.10 426 594 1.4E-13 T 29-03-2018 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 147 239 2.5E-20 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 253 415 1.2E-35 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 149 161 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 SUPERFAMILY SSF47203 257 422 3.22E-45 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 SUPERFAMILY SSF56645 22 263 2.23E-70 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 32 143 4.0E-29 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS24820 c2c775501404b53c49c83fcf03d5e66f 594 Gene3D G3DSA:1.20.140.10 241 425 5.5E-52 T 29-03-2018 CSW12_RS08115 72a8e1c80b35ee7da4dcc0f3a81efba5 263 Pfam PF01734 Patatin-like phospholipase 8 164 1.1E-18 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CSW12_RS08115 72a8e1c80b35ee7da4dcc0f3a81efba5 263 Gene3D G3DSA:3.40.1090.10 1 244 4.4E-43 T 29-03-2018 CSW12_RS08115 72a8e1c80b35ee7da4dcc0f3a81efba5 263 SUPERFAMILY SSF52151 1 257 2.3E-55 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS12015 4202daed3e4af2521cabe3925d954a25 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 62 2.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12015 4202daed3e4af2521cabe3925d954a25 182 Gene3D G3DSA:1.10.10.60 2 54 4.5E-9 T 29-03-2018 CSW12_RS12015 4202daed3e4af2521cabe3925d954a25 182 Gene3D G3DSA:1.10.10.60 55 136 4.4E-6 T 29-03-2018 CSW12_RS12015 4202daed3e4af2521cabe3925d954a25 182 SUPERFAMILY SSF46689 9 75 3.13E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS21765 3f16ef11645da63ca415cc139fbfad70 214 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 205 3.5E-38 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 Gene3D G3DSA:3.90.470.20 1 119 1.9E-34 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 118 2.0E-37 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 11 116 3.0E-55 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 116 1.7E-30 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 25.242 T 29-03-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 110 4.4E-20 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS28685 cd70637952f4020b2cde687bff2d54b8 119 SUPERFAMILY SSF56214 1 115 3.14E-34 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 580 597 6.2E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 597 616 6.2E-8 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 332 345 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Pfam PF02954 Bacterial regulatory protein, Fis family 574 614 2.9E-12 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Gene3D G3DSA:3.30.450.40 80 211 2.6E-4 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Gene3D G3DSA:1.10.8.60 481 551 4.8E-16 T 29-03-2018 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 SUPERFAMILY SSF46689 572 616 5.38E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 395 410 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Pfam PF00158 Sigma-54 interaction domain 309 475 1.5E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Pfam PF01590 GAF domain 106 201 9.5E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 517 526 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 SUPERFAMILY SSF52540 308 545 2.82E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Gene3D G3DSA:3.40.50.300 304 480 3.0E-26 T 29-03-2018 CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 SMART SM00382 328 472 6.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS13860 bab6fa253a99a798bcc374ebc1db2fff 616 Gene3D G3DSA:1.10.10.60 552 616 2.7E-11 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 2.5E-16 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00702 haloacid dehalogenase-like hydrolase 322 646 3.0E-28 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:1.20.1110.10 653 887 1.2E-74 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:3.40.1110.10 287 527 1.0E-54 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SMART SM00831 2 76 2.2E-24 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00122 E1-E2 ATPase 111 304 2.1E-55 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 632 648 4.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 664 689 4.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 604 620 4.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 488 506 4.5E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 9.5E-41 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 9.5E-41 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 9.5E-41 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 9.5E-41 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 9.5E-41 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 9.5E-41 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Pfam PF00689 Cation transporting ATPase, C-terminus 716 881 2.9E-51 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF56784 485 736 3.82E-65 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF56784 322 342 3.82E-65 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:2.70.150.10 11 225 8.0E-53 T 29-03-2018 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81660 332 534 1.07E-57 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 211 345 2.2E-28 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 598 722 3.6E-38 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 183 2.2E-19 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 53 881 1.3E-216 T 29-03-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 Gene3D G3DSA:3.40.50.1000 528 652 3.7E-22 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81653 114 224 9.29E-32 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81665 225 318 2.09E-135 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81665 682 881 2.09E-135 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS08400 0d8d3a8c216ea51fccc919b558bf09e1 907 SUPERFAMILY SSF81665 1 114 2.09E-135 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS28930 06ba9d25d1af6c04d7d655726f92d63f 319 PIRSF PIRSF000196 9 311 3.2E-98 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CSW12_RS28930 06ba9d25d1af6c04d7d655726f92d63f 319 SUPERFAMILY SSF51730 45 305 1.02E-54 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CSW12_RS28930 06ba9d25d1af6c04d7d655726f92d63f 319 Gene3D G3DSA:3.20.20.220 5 318 4.8E-49 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CSW12_RS28930 06ba9d25d1af6c04d7d655726f92d63f 319 Pfam PF01619 Proline dehydrogenase 54 297 8.8E-17 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CSW12_RS13685 91818be41d5e20b72118af74d67a2381 167 Gene3D G3DSA:3.40.50.300 1 162 2.6E-17 T 29-03-2018 CSW12_RS13685 91818be41d5e20b72118af74d67a2381 167 SUPERFAMILY SSF52540 1 99 1.43E-16 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 SMART SM00859 2 141 1.3E-48 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 SUPERFAMILY SSF51735 2 177 2.22E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 Gene3D G3DSA:3.30.360.10 161 313 2.4E-59 T 29-03-2018 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 140 7.4E-34 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 SUPERFAMILY SSF55347 149 313 7.73E-54 T 29-03-2018 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 316 3.7E-28 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 29-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 344 1.3E-138 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 43.75 T 29-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS20210 4f53b7a6449e57076925e57a26f52a2f 345 Gene3D G3DSA:3.40.50.720 1 160 4.2E-38 T 29-03-2018 CSW12_RS23960 ca4514bbf756a8a444633601b9a00c67 367 TIGRFAM TIGR01437 selA_rel: uncharacterized pyridoxal phosphate-dependent enzyme 6 364 3.4E-168 T 29-03-2018 IPR006337 Pyridoxal phosphate-dependent enzyme, SelA-like KEGG: 00030+4.3.1.29|MetaCyc: PWY-7310 CSW12_RS23960 ca4514bbf756a8a444633601b9a00c67 367 Pfam PF03841 L-seryl-tRNA selenium transferase 57 277 2.3E-12 T 29-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CSW12_RS23960 ca4514bbf756a8a444633601b9a00c67 367 Gene3D G3DSA:3.40.640.10 27 276 5.4E-19 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS23960 ca4514bbf756a8a444633601b9a00c67 367 SUPERFAMILY SSF53383 10 362 2.14E-37 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 496 514 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 520 533 4.0E-16 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Gene3D G3DSA:2.40.50.180 559 618 2.2E-6 T 29-03-2018 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Gene3D G3DSA:1.20.120.160 1 138 8.5E-31 T 29-03-2018 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SMART SM00260 528 672 1.5E-28 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SMART SM00387 393 536 3.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 289 346 4.5E-7 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SUPERFAMILY SSF50341 535 672 1.44E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Pfam PF01627 Hpt domain 4 103 6.3E-18 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Pfam PF01584 CheW-like domain 541 672 9.1E-24 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SUPERFAMILY SSF55874 350 534 6.68E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Gene3D G3DSA:1.10.287.560 288 347 5.8E-12 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SMART SM00073 2 99 9.9E-34 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SUPERFAMILY SSF55052 147 225 1.28E-18 T 29-03-2018 IPR015162 CheY binding CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 535 7.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Gene3D G3DSA:3.30.70.1110 147 224 1.9E-18 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Gene3D G3DSA:2.30.30.40 619 672 4.6E-18 T 29-03-2018 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SMART SM01231 288 348 2.7E-11 T 29-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SUPERFAMILY SSF47384 289 349 3.22E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Gene3D G3DSA:3.30.565.10 348 538 3.9E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 SUPERFAMILY SSF47226 3 124 1.96E-32 T 29-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CSW12_RS19425 5a018403d1e340db08d537c6fad37292 672 Pfam PF07194 P2 response regulator binding domain 148 225 1.1E-19 T 29-03-2018 IPR010808 Signal transduction histidine kinase, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 SUPERFAMILY SSF52374 1 200 2.69E-155 T 29-03-2018 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 SUPERFAMILY SSF52374 392 639 2.69E-155 T 29-03-2018 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 632 8.6E-224 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 21.208 T 29-03-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Gene3D G3DSA:3.30.2320.20 790 883 1.1E-24 T 29-03-2018 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Gene3D G3DSA:1.10.730.10 599 788 5.2E-42 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Gene3D G3DSA:3.40.50.620 386 598 7.0E-56 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 831 0.0 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Pfam PF06827 Zinc finger found in FPG and IleRS 885 914 1.1E-7 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Pfam PF08264 Anticodon-binding domain of tRNA 676 829 2.2E-31 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 SUPERFAMILY SSF47323 643 917 2.43E-81 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 SUPERFAMILY SSF50677 202 392 6.7E-65 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Gene3D G3DSA:3.40.50.620 52 195 1.8E-5 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 6.8E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 518 531 6.8E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 6.8E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 552 561 6.8E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 390 405 6.8E-33 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS08280 587e5f274ccfe64e2ab3a4fd85b41d9c 921 Gene3D G3DSA:3.90.740.10 196 385 1.2E-73 T 29-03-2018 CSW12_RS27520 acabdc58918924bc0667a13f0a653e58 96 Pfam PF01541 GIY-YIG catalytic domain 5 77 9.3E-16 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS27520 acabdc58918924bc0667a13f0a653e58 96 Gene3D G3DSA:3.40.1440.10 2 88 2.9E-6 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS27520 acabdc58918924bc0667a13f0a653e58 96 SUPERFAMILY SSF82771 5 76 1.31E-12 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS27520 acabdc58918924bc0667a13f0a653e58 96 SMART SM00465 5 83 0.0017 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS29400 fe17fd6800f3a6829a510d3492f770b8 146 Pfam PF14040 Deoxyribonuclease NucA/NucB 51 145 2.4E-12 T 29-03-2018 IPR029476 Deoxyribonuclease NucA/NucB CSW12_RS02795 c457a715dbfc63d0da5019a634524645 174 Gene3D G3DSA:3.40.50.300 3 174 4.5E-15 T 29-03-2018 CSW12_RS02795 c457a715dbfc63d0da5019a634524645 174 SUPERFAMILY SSF52540 5 172 8.44E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02795 c457a715dbfc63d0da5019a634524645 174 Pfam PF13671 AAA domain 6 140 4.7E-13 T 29-03-2018 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 Gene3D G3DSA:2.10.10.20 416 454 4.4E-10 T 29-03-2018 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 SMART SM00060 314 391 1.1E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 SMART SM00060 220 293 3.0E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 SUPERFAMILY SSF81296 41 209 3.92E-58 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 Gene3D G3DSA:2.60.40.10 203 302 7.2E-21 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 Gene3D G3DSA:2.60.40.10 312 415 4.2E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 SUPERFAMILY SSF49265 219 403 5.66E-29 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 Pfam PF00041 Fibronectin type III domain 316 391 1.2E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 Gene3D G3DSA:2.70.50.50 41 202 2.7E-53 T 29-03-2018 CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 207 2.0E-39 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CSW12_RS13700 ac8279ea7c837fd992117e0a7050ce91 455 SUPERFAMILY SSF51055 408 440 2.75E-5 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82714 183 258 1.7E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Gene3D G3DSA:3.30.2090.10 179 259 1.6E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Gene3D G3DSA:3.30.2090.10 694 773 4.2E-16 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82714 688 770 1.7E-11 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Gene3D G3DSA:3.30.70.1430 540 693 7.1E-5 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Gene3D G3DSA:3.30.70.1430 41 140 6.7E-21 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Pfam PF00873 AcrB/AcrD/AcrF family 5 992 7.8E-211 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Gene3D G3DSA:1.20.1640.10 774 994 9.5E-45 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 Gene3D G3DSA:1.20.1640.10 260 486 9.8E-44 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82693 261 306 4.5E-10 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82693 156 180 4.5E-10 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 431 454 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 323 346 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 456 479 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 350 371 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 PRINTS PR00702 Acriflavin resistance protein family signature 378 402 2.6E-36 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82693 41 132 2.67E-17 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82866 286 483 1.7E-37 T 29-03-2018 CSW12_RS02800 d831324dcc1234130738d96fa6ce3d6b 1014 SUPERFAMILY SSF82866 773 995 2.88E-48 T 29-03-2018 CSW12_RS20590 2a35bd56746b0f38a657d51697bfa633 168 Pfam PF11085 Conserved membrane protein YqhR 16 157 1.3E-40 T 29-03-2018 IPR024563 Uncharacterised protein family YqhR CSW12_RS20590 2a35bd56746b0f38a657d51697bfa633 168 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 9 148 1.0E-62 T 29-03-2018 IPR024563 Uncharacterised protein family YqhR CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 Pfam PF02195 ParB-like nuclease domain 28 115 1.8E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 Pfam PF01381 Helix-turn-helix 133 166 1.3E-5 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 24 201 2.3E-61 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 SMART SM00470 27 116 2.8E-34 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 SUPERFAMILY SSF110849 31 118 2.33E-27 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 SUPERFAMILY SSF109709 108 219 1.28E-36 T 29-03-2018 CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 Gene3D G3DSA:3.90.1530.10 17 116 2.0E-35 T 29-03-2018 CSW12_RS27260 74896ef68809a2f39cee77b4f0903421 285 Gene3D G3DSA:1.10.10.730 117 164 3.2E-20 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.4E-10 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 1.4E-10 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.4E-10 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 412 2.0E-145 T 29-03-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 4.0E-6 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.0E-6 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 SUPERFAMILY SSF51905 358 415 1.4E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 SUPERFAMILY SSF51905 1 194 1.4E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 Gene3D G3DSA:3.50.50.60 1 423 2.7E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 Pfam PF03486 HI0933-like protein 3 413 2.6E-157 T 29-03-2018 CSW12_RS23225 76292fad73fa0ed1cf40d41d353662b5 423 SUPERFAMILY SSF160996 193 361 1.26E-46 T 29-03-2018 CSW12_RS07155 7461a36a17cdcfe36b549747cf8cdde2 332 SUPERFAMILY SSF53474 39 321 1.5E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS07155 7461a36a17cdcfe36b549747cf8cdde2 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 125 139 7.3E-9 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CSW12_RS07155 7461a36a17cdcfe36b549747cf8cdde2 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 7.3E-9 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CSW12_RS07155 7461a36a17cdcfe36b549747cf8cdde2 332 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 77 88 7.3E-9 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CSW12_RS07155 7461a36a17cdcfe36b549747cf8cdde2 332 Pfam PF12146 Serine aminopeptidase, S33 48 161 2.3E-15 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS07155 7461a36a17cdcfe36b549747cf8cdde2 332 Gene3D G3DSA:3.40.50.1820 40 327 4.3E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12615 0a72fbda12608382e690511939c5539a 309 PIRSF PIRSF002849 1 305 4.1E-123 T 29-03-2018 CSW12_RS12615 0a72fbda12608382e690511939c5539a 309 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 32 162 5.5E-61 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CSW12_RS12615 0a72fbda12608382e690511939c5539a 309 SUPERFAMILY SSF52540 3 273 4.15E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12615 0a72fbda12608382e690511939c5539a 309 Gene3D G3DSA:1.10.8.300 193 300 3.5E-30 T 29-03-2018 CSW12_RS12615 0a72fbda12608382e690511939c5539a 309 Gene3D G3DSA:3.40.50.300 13 179 7.0E-27 T 29-03-2018 CSW12_RS11090 08ce65be2fee152ff1a5ac3554180a4a 255 SUPERFAMILY SSF53448 1 255 3.76E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS11090 08ce65be2fee152ff1a5ac3554180a4a 255 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 255 9.4E-146 T 29-03-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 CSW12_RS11090 08ce65be2fee152ff1a5ac3554180a4a 255 Gene3D G3DSA:3.90.550.10 1 255 4.2E-49 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS11090 08ce65be2fee152ff1a5ac3554180a4a 255 Pfam PF00483 Nucleotidyl transferase 2 225 2.2E-19 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 SUPERFAMILY SSF53182 1 214 4.32E-73 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 40.638 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 Pfam PF01470 Pyroglutamyl peptidase 3 201 1.2E-84 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 212 7.9E-84 T 29-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 PIRSF PIRSF015592 1 213 4.6E-89 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 29-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 Gene3D G3DSA:3.40.630.20 1 215 3.6E-63 T 29-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 29-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 4.9E-48 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 4.9E-48 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 4.9E-48 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 4.9E-48 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CSW12_RS12320 454cc7ef334c562d689c5d05c36226d8 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 4.9E-48 T 29-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CSW12_RS25885 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS25885 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS07000 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS07000 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS22855 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS22855 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS23175 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS23175 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS04690 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS04690 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS03140 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS03140 581ee8faa76e35b1f03b1d56a780c92e 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS16935 af4481448fda1f1e72b3a8050aa8ff4f 400 Gene3D G3DSA:3.40.50.1970 10 184 1.1E-52 T 29-03-2018 CSW12_RS16935 af4481448fda1f1e72b3a8050aa8ff4f 400 Gene3D G3DSA:1.20.1090.10 185 396 2.6E-61 T 29-03-2018 CSW12_RS16935 af4481448fda1f1e72b3a8050aa8ff4f 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 379 2.9E-128 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CSW12_RS16935 af4481448fda1f1e72b3a8050aa8ff4f 400 SUPERFAMILY SSF56796 6 388 1.3E-126 T 29-03-2018 CSW12_RS16935 af4481448fda1f1e72b3a8050aa8ff4f 400 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 Gene3D G3DSA:2.40.40.10 84 294 1.6E-40 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 SMART SM00287 89 148 1.9E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 SMART SM00287 27 88 4.9E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 Gene3D G3DSA:2.40.50.110 22 83 6.8E-16 T 29-03-2018 CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 Pfam PF06725 3D domain 236 296 6.1E-21 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 Pfam PF08239 Bacterial SH3 domain 36 84 3.7E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 Pfam PF08239 Bacterial SH3 domain 95 142 8.8E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25960 32cd4a2dc2b5d5cd4f07246af042aff1 296 SUPERFAMILY SSF50685 234 286 6.98E-11 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 208 215 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 SUPERFAMILY SSF53720 5 434 2.36E-121 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 PIRSF PIRSF036492 1 455 3.9E-183 T 29-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 Pfam PF00171 Aldehyde dehydrogenase family 7 427 8.3E-88 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 Gene3D G3DSA:3.40.309.10 228 407 7.6E-63 T 29-03-2018 CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 Gene3D G3DSA:3.40.605.10 2 227 7.4E-67 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS05965 5ba39da76fda4adb260bc3a96fc00edd 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 236 247 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS25000 b443aca10d30c0db82fb77eb46cd9f48 105 Gene3D G3DSA:3.30.300.130 3 103 1.5E-27 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS25000 b443aca10d30c0db82fb77eb46cd9f48 105 Pfam PF01883 Iron-sulfur cluster assembly protein 10 82 5.7E-18 T 29-03-2018 IPR002744 MIP18 family-like CSW12_RS25000 b443aca10d30c0db82fb77eb46cd9f48 105 SUPERFAMILY SSF117916 4 102 5.23E-30 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS19090 c923c3e427b1c5331aed3691d07faa48 363 SUPERFAMILY SSF56601 243 348 3.18E-27 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS19090 c923c3e427b1c5331aed3691d07faa48 363 SUPERFAMILY SSF56601 40 184 3.18E-27 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS19090 c923c3e427b1c5331aed3691d07faa48 363 Pfam PF13354 Beta-lactamase enzyme family 57 278 1.6E-17 T 29-03-2018 CSW12_RS19090 c923c3e427b1c5331aed3691d07faa48 363 Gene3D G3DSA:3.40.710.10 39 351 1.3E-20 T 29-03-2018 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 SUPERFAMILY SSF53067 3 140 9.79E-39 T 29-03-2018 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 5.1E-136 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 Gene3D G3DSA:3.30.420.40 154 238 4.2E-30 T 29-03-2018 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 Gene3D G3DSA:3.30.420.40 239 309 2.9E-7 T 29-03-2018 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 SUPERFAMILY SSF53067 143 325 3.44E-47 T 29-03-2018 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 Pfam PF06723 MreB/Mbl protein 4 327 7.1E-148 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 9.2E-58 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 9.2E-58 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 9.2E-58 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 9.2E-58 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 9.2E-58 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS26170 ca8d2b094c938a665db0459a285aa7be 333 Gene3D G3DSA:3.30.420.40 1 153 3.6E-36 T 29-03-2018 CSW12_RS10000 c82cdf23e6dc62d835dde86fdef0cb71 477 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 39 434 3.1E-89 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS10000 c82cdf23e6dc62d835dde86fdef0cb71 477 Pfam PF00474 Sodium:solute symporter family 39 434 8.8E-98 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS10000 c82cdf23e6dc62d835dde86fdef0cb71 477 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 158 183 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CSW12_RS10000 c82cdf23e6dc62d835dde86fdef0cb71 477 TIGRFAM TIGR02119 panF: sodium/pantothenate symporter 3 474 2.5E-240 T 29-03-2018 IPR011849 Sodium/pantothenate symporter GO:0015081|GO:0015233|GO:0015887|GO:0016021|GO:0031402|GO:0071436 CSW12_RS23070 7ce6c2777e3fb661d43674170312f7e0 109 SUPERFAMILY SSF52833 2 105 6.78E-10 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS23070 7ce6c2777e3fb661d43674170312f7e0 109 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 6 105 2.6E-39 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 CSW12_RS23070 7ce6c2777e3fb661d43674170312f7e0 109 Pfam PF11009 Protein of unknown function (DUF2847) 6 104 1.9E-37 T 29-03-2018 IPR022551 Protein of unknown function DUF2847 CSW12_RS23070 7ce6c2777e3fb661d43674170312f7e0 109 Gene3D G3DSA:3.40.30.10 4 106 2.5E-39 T 29-03-2018 CSW12_RS14285 e17e5cee7b343cff667f2a3e9c8900a7 338 Pfam PF00144 Beta-lactamase 10 316 7.4E-33 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS14285 e17e5cee7b343cff667f2a3e9c8900a7 338 Gene3D G3DSA:3.40.710.10 3 335 7.7E-46 T 29-03-2018 CSW12_RS14285 e17e5cee7b343cff667f2a3e9c8900a7 338 SUPERFAMILY SSF56601 4 320 6.29E-51 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 SUPERFAMILY SSF160240 218 295 6.54E-17 T 29-03-2018 CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 SUPERFAMILY SSF161111 7 214 9.94E-53 T 29-03-2018 CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 218 294 2.6E-17 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 Pfam PF01545 Cation efflux family 15 209 3.3E-45 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 Gene3D G3DSA:1.20.1510.10 13 213 6.1E-46 T 29-03-2018 CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 294 1.2E-74 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CSW12_RS21690 b11f5cb687dafe438f718284214b1fa5 297 Gene3D G3DSA:3.30.70.1350 214 297 4.4E-14 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CSW12_RS22580 5396fbf2cf6f1ceb8764b8e621e3c628 157 Pfam PF01575 MaoC like domain 24 124 5.6E-9 T 29-03-2018 IPR002539 MaoC-like domain CSW12_RS22580 5396fbf2cf6f1ceb8764b8e621e3c628 157 SUPERFAMILY SSF54637 8 144 1.92E-23 T 29-03-2018 IPR029069 HotDog domain CSW12_RS22580 5396fbf2cf6f1ceb8764b8e621e3c628 157 Gene3D G3DSA:3.10.129.10 10 143 9.0E-25 T 29-03-2018 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 Gene3D G3DSA:3.30.420.40 195 395 2.0E-78 T 29-03-2018 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 Gene3D G3DSA:3.30.420.40 3 194 4.6E-81 T 29-03-2018 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PIRSF PIRSF000722 1 396 1.3E-153 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 Pfam PF00871 Acetokinase family 3 388 1.4E-171 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PRINTS PR00471 Acetate kinase family signature 172 185 3.7E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PRINTS PR00471 Acetate kinase family signature 202 223 3.7E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PRINTS PR00471 Acetate kinase family signature 299 312 3.7E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PRINTS PR00471 Acetate kinase family signature 321 337 3.7E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PRINTS PR00471 Acetate kinase family signature 4 15 3.7E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 PRINTS PR00471 Acetate kinase family signature 375 387 3.7E-47 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 SUPERFAMILY SSF53067 156 393 1.67E-93 T 29-03-2018 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 SUPERFAMILY SSF53067 1 194 7.77E-74 T 29-03-2018 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 393 1.6E-178 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS22815 30b112f1228bc60b6d17acb15d1f14e7 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 196.672 T 29-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 Pfam PF00406 Adenylate kinase 5 189 8.0E-60 T 29-03-2018 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 SUPERFAMILY SSF52540 1 212 1.63E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 Gene3D G3DSA:3.40.50.300 1 213 6.8E-63 T 29-03-2018 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.944 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 PRINTS PR00094 Adenylate kinase signature 4 17 9.1E-33 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 PRINTS PR00094 Adenylate kinase signature 177 191 9.1E-33 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 PRINTS PR00094 Adenylate kinase signature 81 97 9.1E-33 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 PRINTS PR00094 Adenylate kinase signature 160 175 9.1E-33 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 PRINTS PR00094 Adenylate kinase signature 32 46 9.1E-33 T 29-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 29-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 2.4E-78 T 29-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CSW12_RS28090 ad5bd240f2918717ed6f2fbf0968f300 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 3.3E-18 T 29-03-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 SUPERFAMILY SSF52540 256 489 8.84E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 SUPERFAMILY SSF52540 3 225 4.96E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 Gene3D G3DSA:3.40.50.300 250 493 1.1E-38 T 29-03-2018 CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 Gene3D G3DSA:3.40.50.300 1 247 1.6E-52 T 29-03-2018 CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 SMART SM00382 29 218 1.9E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 Pfam PF00005 ABC transporter 274 429 7.7E-18 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS08825 eee2d55bcfbb61556cdb6400cbe6273b 510 Pfam PF00005 ABC transporter 21 169 4.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26835 eb2a1b46b1303dfca5579e322eb34f86 208 Gene3D G3DSA:3.40.50.360 3 208 3.6E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS26835 eb2a1b46b1303dfca5579e322eb34f86 208 SUPERFAMILY SSF52218 1 208 1.19E-46 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS26835 eb2a1b46b1303dfca5579e322eb34f86 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 28.781 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CSW12_RS26835 eb2a1b46b1303dfca5579e322eb34f86 208 Pfam PF02525 Flavodoxin-like fold 3 203 3.7E-41 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS11965 b8329a82804254476ec6ddcc1100a9a8 618 SUPERFAMILY SSF53474 373 611 5.03E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11965 b8329a82804254476ec6ddcc1100a9a8 618 SUPERFAMILY SSF51735 1 294 1.75E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11965 b8329a82804254476ec6ddcc1100a9a8 618 Gene3D G3DSA:3.40.50.1820 356 612 3.1E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11965 b8329a82804254476ec6ddcc1100a9a8 618 Pfam PF12697 Alpha/beta hydrolase family 382 607 5.4E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS11965 b8329a82804254476ec6ddcc1100a9a8 618 Pfam PF07993 Male sterility protein 6 239 6.9E-40 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CSW12_RS11965 b8329a82804254476ec6ddcc1100a9a8 618 Gene3D G3DSA:3.40.50.720 2 327 7.5E-29 T 29-03-2018 CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 266 425 7.6E-47 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 SUPERFAMILY SSF55073 274 428 1.1E-45 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 Gene3D G3DSA:3.30.450.20 141 258 1.5E-5 T 29-03-2018 CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 Pfam PF13188 PAS domain 145 180 0.0014 T 29-03-2018 IPR000014 PAS domain CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 Gene3D G3DSA:3.30.70.270 262 431 2.1E-49 T 29-03-2018 CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 SMART SM00267 258 426 3.5E-58 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS07465 ca85d1a22d532ccf9db35ef6868d7147 431 Pfam PF00990 Diguanylate cyclase, GGDEF domain 269 422 4.7E-45 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Gene3D G3DSA:3.30.30.80 3 54 1.1E-19 T 29-03-2018 CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Gene3D G3DSA:3.30.1370.50 137 205 2.7E-21 T 29-03-2018 IPR001374 R3H domain GO:0003676 CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 SUPERFAMILY SSF82708 149 204 4.45E-12 T 29-03-2018 IPR001374 R3H domain GO:0003676 CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Pfam PF01424 R3H domain 145 203 9.8E-18 T 29-03-2018 IPR001374 R3H domain GO:0003676 CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Pfam PF13083 KH domain 64 128 1.8E-17 T 29-03-2018 CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 SMART SM01245 5 57 4.1E-22 T 29-03-2018 IPR032782 Jag, N-terminal CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Pfam PF14804 Jag N-terminus 7 55 3.2E-19 T 29-03-2018 IPR032782 Jag, N-terminal CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 Gene3D G3DSA:3.30.300.20 58 135 6.9E-21 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS27290 bdf6ac1c2a39c6c90402c5cae4bec4a4 205 SMART SM00393 126 205 5.8E-24 T 29-03-2018 IPR001374 R3H domain GO:0003676 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 Gene3D G3DSA:3.20.20.70 1 327 1.3E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 6 310 1.1E-68 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 SMART SM01240 3 327 4.0E-119 T 29-03-2018 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 Hamap MF_01511 GMP reductase [guaC]. 2 325 64.85 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 204 224 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 165 177 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 SUPERFAMILY SSF51412 4 314 1.57E-93 T 29-03-2018 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 4 324 3.7E-205 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CSW12_RS27120 94805437b5d9bcb3eabfbfcd5c3f3042 327 PIRSF PIRSF036500 1 326 2.2E-200 T 29-03-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 SUPERFAMILY SSF46589 815 879 1.52E-17 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Gene3D G3DSA:3.90.740.10 242 438 5.0E-67 T 29-03-2018 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Gene3D G3DSA:1.10.730.10 524 748 1.4E-83 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Gene3D G3DSA:3.90.740.10 198 241 9.9E-14 T 29-03-2018 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 SUPERFAMILY SSF47323 577 829 4.67E-79 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 SUPERFAMILY SSF52374 6 198 1.1E-145 T 29-03-2018 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 SUPERFAMILY SSF52374 346 576 1.1E-145 T 29-03-2018 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Pfam PF08264 Anticodon-binding domain of tRNA 609 755 2.2E-45 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 566 6.2E-224 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 815 879 1.0E-25 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 SUPERFAMILY SSF50677 196 347 1.44E-64 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 PRINTS PR00986 Valyl-tRNA synthetase signature 446 467 2.2E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 2.2E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 2.2E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 2.2E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 PRINTS PR00986 Valyl-tRNA synthetase signature 478 496 2.2E-38 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Gene3D G3DSA:3.40.50.620 22 197 1.6E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 880 16.239 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Gene3D G3DSA:1.10.287.380 808 878 2.3E-25 T 29-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 TIGRFAM TIGR00422 valS: valine--tRNA ligase 9 862 0.0 T 29-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CSW12_RS21925 aa78a9efbb6141bb1b6bc1e63ad9d037 881 Gene3D G3DSA:3.40.50.620 439 523 4.1E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS25850 6e3c4fc40b2903a40886f24d69c624d7 452 Pfam PF02040 Arsenical pump membrane protein 8 446 1.2E-67 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS25850 6e3c4fc40b2903a40886f24d69c624d7 452 PRINTS PR00758 Arsenical pump membrane protein signature 385 410 3.1E-24 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS25850 6e3c4fc40b2903a40886f24d69c624d7 452 PRINTS PR00758 Arsenical pump membrane protein signature 344 366 3.1E-24 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS25850 6e3c4fc40b2903a40886f24d69c624d7 452 PRINTS PR00758 Arsenical pump membrane protein signature 418 442 3.1E-24 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS25850 6e3c4fc40b2903a40886f24d69c624d7 452 PRINTS PR00758 Arsenical pump membrane protein signature 105 129 3.1E-24 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS18485 99243ffcddad65ede3392af871eadb61 682 SUPERFAMILY SSF53335 386 626 1.17E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS18485 99243ffcddad65ede3392af871eadb61 682 Pfam PF08242 Methyltransferase domain 427 537 7.0E-19 T 29-03-2018 IPR013217 Methyltransferase type 12 CSW12_RS18485 99243ffcddad65ede3392af871eadb61 682 Gene3D G3DSA:3.40.50.150 375 587 2.5E-21 T 29-03-2018 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 SUPERFAMILY SSF53822 60 330 1.16E-71 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 Gene3D G3DSA:3.40.50.2300 58 164 3.7E-28 T 29-03-2018 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 309 3.1E-32 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 Gene3D G3DSA:1.10.260.40 2 57 3.2E-22 T 29-03-2018 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.5E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 SMART SM00354 1 71 6.9E-32 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 SUPERFAMILY SSF47413 3 59 2.55E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS04745 f8f381c80fd942857c8d4b88b2faa4ee 337 Gene3D G3DSA:3.40.50.2300 165 332 1.7E-41 T 29-03-2018 CSW12_RS01685 55a3b7ffc6f3749812a7eb82c32cac80 471 PIRSF PIRSF006060 5 470 8.8E-93 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS01685 55a3b7ffc6f3749812a7eb82c32cac80 471 Pfam PF13520 Amino acid permease 26 430 1.6E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS22875 f402253d877c096c70f68e3d50369c9f 65 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 6 60 1.1E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS22875 f402253d877c096c70f68e3d50369c9f 65 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 39 53 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS22875 f402253d877c096c70f68e3d50369c9f 65 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 21 30 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS09770 7a344c4f6adabaa0efe13fe30edf7887 343 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 240 9.6E-17 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CSW12_RS09770 7a344c4f6adabaa0efe13fe30edf7887 343 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 2.6E-22 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CSW12_RS09770 7a344c4f6adabaa0efe13fe30edf7887 343 Gene3D G3DSA:3.30.360.10 134 343 2.4E-41 T 29-03-2018 CSW12_RS09770 7a344c4f6adabaa0efe13fe30edf7887 343 Gene3D G3DSA:3.40.50.720 1 133 7.7E-34 T 29-03-2018 CSW12_RS09770 7a344c4f6adabaa0efe13fe30edf7887 343 SUPERFAMILY SSF51735 2 197 7.31E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 PIRSF PIRSF006246 1 126 1.7E-55 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 74.571 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 Pfam PF02261 Aspartate decarboxylase 1 114 2.9E-54 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 SUPERFAMILY SSF50692 1 120 7.04E-52 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 90 6.0E-44 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 Gene3D G3DSA:2.40.40.20 1 117 2.1E-55 T 29-03-2018 CSW12_RS19885 b28c9fe46bcbdb3f7840b4d9814f94e5 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 3.4E-57 T 29-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Pfam PF08239 Bacterial SH3 domain 68 117 1.3E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Pfam PF08239 Bacterial SH3 domain 139 189 4.1E-16 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Pfam PF08239 Bacterial SH3 domain 224 274 7.1E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Gene3D G3DSA:2.40.50.110 34 119 1.4E-19 T 29-03-2018 CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Gene3D G3DSA:2.40.50.110 120 192 4.5E-20 T 29-03-2018 CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Gene3D G3DSA:2.40.50.110 195 276 8.3E-18 T 29-03-2018 CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Pfam PF00877 NlpC/P60 family 325 428 5.6E-24 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 Gene3D G3DSA:3.90.1720.10 302 432 9.5E-29 T 29-03-2018 CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 SMART SM00287 215 276 1.3E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 SMART SM00287 59 120 7.6E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 SMART SM00287 131 193 2.0E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS18080 cfc8f2d2902bfdcb6c2620f482d757b6 432 SUPERFAMILY SSF54001 306 430 2.39E-31 T 29-03-2018 CSW12_RS22890 15c7ef0c7e5f119f5aa4d30bc4fdb146 570 Pfam PF06160 Septation ring formation regulator, EzrA 7 561 7.6E-172 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CSW12_RS22890 15c7ef0c7e5f119f5aa4d30bc4fdb146 570 Gene3D G3DSA:1.20.120.20 31 565 3.3E-4 T 29-03-2018 CSW12_RS22890 15c7ef0c7e5f119f5aa4d30bc4fdb146 570 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 5 566 21.826 T 29-03-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 CSW12_RS08860 d5ebca43c4ec5c88e37652cf65bbed93 261 PIRSF PIRSF021288 1 260 1.2E-142 T 29-03-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain CSW12_RS08860 d5ebca43c4ec5c88e37652cf65bbed93 261 Gene3D G3DSA:3.30.70.260 10 71 6.5E-5 T 29-03-2018 CSW12_RS08860 d5ebca43c4ec5c88e37652cf65bbed93 261 Pfam PF11868 Protein of unknown function (DUF3388) 70 259 5.0E-107 T 29-03-2018 IPR024514 Domain of unknown function DUF3388 CSW12_RS08860 d5ebca43c4ec5c88e37652cf65bbed93 261 SUPERFAMILY SSF55021 3 73 4.58E-9 T 29-03-2018 CSW12_RS24285 c2893370abc5fc6f998569754e81cbe0 77 Pfam PF04070 Domain of unknown function (DUF378) 3 61 4.7E-26 T 29-03-2018 IPR007211 Protein of unknown function DUF378 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 Gene3D G3DSA:1.20.1250.20 6 197 6.0E-34 T 29-03-2018 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 Gene3D G3DSA:1.20.1250.20 249 468 6.0E-29 T 29-03-2018 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 SUPERFAMILY SSF103473 11 194 3.27E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 SUPERFAMILY SSF103473 245 451 3.27E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 3.2E-5 T 29-03-2018 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 3.2E-5 T 29-03-2018 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 3.2E-5 T 29-03-2018 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 3.2E-5 T 29-03-2018 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 10 415 9.1E-99 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS16160 97ef61334a7ff9195f1ccae34ac37d76 476 Pfam PF07690 Major Facilitator Superfamily 17 406 1.0E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 Gene3D G3DSA:1.10.8.60 167 242 2.1E-21 T 29-03-2018 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 3.6E-148 T 29-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 SMART SM00382 37 185 2.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 Gene3D G3DSA:3.40.50.300 1 166 5.5E-44 T 29-03-2018 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 SUPERFAMILY SSF48019 244 360 7.48E-29 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 SUPERFAMILY SSF52540 31 224 7.83E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 Gene3D G3DSA:1.20.272.10 243 363 8.8E-18 T 29-03-2018 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 7.1E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 7.1E-6 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 360 5.6E-14 T 29-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CSW12_RS27435 fb2fea585301b196d3c084cde486bd34 562 Pfam PF13177 DNA polymerase III, delta subunit 20 178 9.6E-47 T 29-03-2018 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Gene3D G3DSA:3.10.450.100 22 138 4.9E-38 T 29-03-2018 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 SUPERFAMILY SSF56519 144 331 8.89E-44 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 24 142 8.6E-41 T 29-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Pfam PF03717 Penicillin-binding Protein dimerisation domain 150 317 2.5E-36 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 658 3.3E-66 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 SUPERFAMILY SSF56601 332 660 1.71E-81 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Gene3D G3DSA:3.90.1310.10 230 326 9.4E-28 T 29-03-2018 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Gene3D G3DSA:3.30.1390.30 172 229 2.9E-18 T 29-03-2018 CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 SUPERFAMILY SSF54427 27 141 6.31E-34 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS16850 fe6ee35a2071cad4f24656683a861762 661 Gene3D G3DSA:3.40.710.10 327 661 1.1E-64 T 29-03-2018 CSW12_RS28300 6239cc423471428c0c585e93bfc810f3 188 Pfam PF14066 Protein of unknown function (DUF4256) 16 188 5.1E-93 T 29-03-2018 IPR025352 Protein of unknown function DUF4256 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Gene3D G3DSA:3.50.40.10 204 405 1.6E-73 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Pfam PF03147 Ferredoxin-fold anticodon binding domain 712 805 6.3E-31 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SUPERFAMILY SSF50249 36 199 1.08E-48 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 805 9.4E-269 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Gene3D G3DSA:3.30.56.10 1 53 1.5E-14 T 29-03-2018 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Gene3D G3DSA:3.30.56.10 409 483 1.9E-21 T 29-03-2018 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Pfam PF01588 Putative tRNA binding domain 46 152 7.2E-27 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SUPERFAMILY SSF56037 208 405 3.92E-72 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Gene3D G3DSA:3.30.70.380 708 805 2.7E-29 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SMART SM00874 411 479 9.7E-26 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SUPERFAMILY SSF46955 412 483 7.23E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Pfam PF03483 B3/4 domain 222 394 2.8E-67 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Gene3D G3DSA:3.30.930.10 497 699 1.6E-36 T 29-03-2018 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 799 46.814 T 29-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SMART SM00896 712 805 4.0E-46 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Pfam PF03484 tRNA synthetase B5 domain 414 479 1.2E-17 T 29-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SUPERFAMILY SSF55681 475 695 4.92E-51 T 29-03-2018 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SMART SM00873 221 394 6.7E-92 T 29-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 Gene3D G3DSA:2.40.50.140 54 161 4.8E-42 T 29-03-2018 CSW12_RS22415 ef454256f97016abdb62cb059b0e009a 806 SUPERFAMILY SSF54991 708 805 1.83E-32 T 29-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.7E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 SUPERFAMILY SSF51735 2 248 6.72E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 Pfam PF00106 short chain dehydrogenase 3 201 2.3E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS10025 28994eacbe673ebc1b7f6c1fdd46acde 249 Gene3D G3DSA:3.40.50.720 1 249 2.9E-44 T 29-03-2018 CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 Pfam PF08281 Sigma-70, region 4 119 171 6.8E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 SUPERFAMILY SSF88659 115 176 1.01E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 Gene3D G3DSA:1.10.10.10 113 177 2.2E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 Gene3D G3DSA:1.10.1740.10 2 112 4.9E-20 T 29-03-2018 CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 SUPERFAMILY SSF88946 14 101 7.46E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 Pfam PF04542 Sigma-70 region 2 23 84 8.8E-15 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04480 f3f35c55cd0c351d1c2e5f80a2982cb7 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 174 3.3E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07510 a2a38c31fe20c9765bf722ce259c5531 392 Gene3D G3DSA:3.40.640.10 48 300 3.6E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS07510 a2a38c31fe20c9765bf722ce259c5531 392 Pfam PF00155 Aminotransferase class I and II 34 384 1.2E-67 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS07510 a2a38c31fe20c9765bf722ce259c5531 392 SUPERFAMILY SSF53383 5 387 4.59E-103 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS07510 a2a38c31fe20c9765bf722ce259c5531 392 Gene3D G3DSA:3.90.1150.10 301 388 1.2E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS19755 0966572d067e2575f7092c2f61b30882 197 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 43.076 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CSW12_RS19755 0966572d067e2575f7092c2f61b30882 197 Gene3D G3DSA:3.40.50.2020 3 188 1.3E-24 T 29-03-2018 CSW12_RS19755 0966572d067e2575f7092c2f61b30882 197 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 190 3.6E-86 T 29-03-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 CSW12_RS19755 0966572d067e2575f7092c2f61b30882 197 Pfam PF00156 Phosphoribosyl transferase domain 34 156 2.7E-10 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS19755 0966572d067e2575f7092c2f61b30882 197 SUPERFAMILY SSF53271 1 189 5.4E-48 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 352 2.4E-84 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 Pfam PF07687 Peptidase dimerisation domain 173 263 1.5E-8 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 Gene3D G3DSA:3.40.630.10 2 252 6.3E-47 T 29-03-2018 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 Gene3D G3DSA:3.40.630.10 253 371 3.8E-12 T 29-03-2018 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 SUPERFAMILY SSF53187 280 369 1.98E-62 T 29-03-2018 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 SUPERFAMILY SSF53187 5 182 1.98E-62 T 29-03-2018 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 PIRSF PIRSF005962 1 371 2.3E-89 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 Pfam PF01546 Peptidase family M20/M25/M40 66 364 2.8E-20 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS00540 f1d3878f40ad3b00dd376b7e7e2b7022 371 SUPERFAMILY SSF55031 171 276 7.78E-19 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 SMART SM00490 323 401 0.62 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 SMART SM00490 488 573 5.0E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 SUPERFAMILY SSF50249 6 168 1.05E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Pfam PF00270 DEAD/DEAH box helicase 260 415 2.3E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:2.40.50.140 54 142 1.8E-8 T 29-03-2018 CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:3.40.50.300 441 613 5.3E-31 T 29-03-2018 CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Pfam PF00271 Helicase conserved C-terminal domain 455 572 5.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 SUPERFAMILY SSF52540 173 436 5.33E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:1.10.150.20 4 53 6.2E-6 T 29-03-2018 CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Gene3D G3DSA:3.40.50.300 237 440 4.5E-36 T 29-03-2018 CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 Pfam PF17191 RecG wedge domain 12 164 4.5E-14 T 29-03-2018 IPR033454 RecG, wedge domain CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 3.0E-245 T 29-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 SMART SM00487 253 442 3.3E-33 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS08500 c868cfd3641ac88e58db399864c6439f 682 SUPERFAMILY SSF52540 376 585 7.1E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17245 d01ae6b68db770c026b08af1614d297f 77 Pfam PF02597 ThiS family 4 77 1.2E-14 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CSW12_RS17245 d01ae6b68db770c026b08af1614d297f 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 7.7E-22 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CSW12_RS17245 d01ae6b68db770c026b08af1614d297f 77 SUPERFAMILY SSF54285 1 77 7.85E-17 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CSW12_RS17245 d01ae6b68db770c026b08af1614d297f 77 Gene3D G3DSA:3.10.20.30 2 77 8.9E-17 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 Gene3D G3DSA:3.40.50.800 337 425 1.0E-13 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 Gene3D G3DSA:3.30.930.10 1 336 4.8E-82 T 29-03-2018 CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 SUPERFAMILY SSF52954 338 425 6.87E-18 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 423 24.562 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 PIRSF PIRSF001549 1 425 5.3E-128 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 Pfam PF13393 Histidyl-tRNA synthetase 8 323 2.9E-36 T 29-03-2018 CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 417 5.6E-110 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 SUPERFAMILY SSF55681 5 334 3.32E-70 T 29-03-2018 CSW12_RS11330 aab3030bf52ee6c32de1f01a7f4eb06f 425 Pfam PF03129 Anticodon binding domain 340 425 2.7E-11 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 Pfam PF13377 Periplasmic binding protein-like domain 154 282 6.5E-10 T 29-03-2018 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 Gene3D G3DSA:3.40.50.2300 159 284 1.2E-17 T 29-03-2018 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 SMART SM00354 1 71 4.4E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.0E-20 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 SUPERFAMILY SSF53822 58 287 1.67E-35 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.8E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.8E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 SUPERFAMILY SSF47413 2 59 2.81E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 Gene3D G3DSA:1.10.260.40 2 53 7.2E-21 T 29-03-2018 CSW12_RS07145 e6000d6fb29e131018551e31298afe17 287 Gene3D G3DSA:3.40.50.2300 54 158 2.3E-8 T 29-03-2018 CSW12_RS18615 de162ba4174fa6a1f1d27a704ead806c 299 Gene3D G3DSA:3.30.470.10 1 120 1.3E-35 T 29-03-2018 CSW12_RS18615 de162ba4174fa6a1f1d27a704ead806c 299 Pfam PF01063 Amino-transferase class IV 32 258 6.1E-59 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS18615 de162ba4174fa6a1f1d27a704ead806c 299 SUPERFAMILY SSF56752 3 286 2.62E-93 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS18615 de162ba4174fa6a1f1d27a704ead806c 299 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS18615 de162ba4174fa6a1f1d27a704ead806c 299 Gene3D G3DSA:3.20.10.10 124 287 1.5E-49 T 29-03-2018 CSW12_RS18615 de162ba4174fa6a1f1d27a704ead806c 299 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 287 1.0E-103 T 29-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 SUPERFAMILY SSF52540 283 519 6.62E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 Gene3D G3DSA:3.40.50.300 275 522 1.5E-56 T 29-03-2018 CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 SMART SM00382 31 220 3.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 SMART SM00382 319 502 3.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 Pfam PF00005 ABC transporter 310 453 1.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 Pfam PF00005 ABC transporter 22 171 1.7E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 Gene3D G3DSA:3.40.50.300 3 240 1.8E-57 T 29-03-2018 CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 SUPERFAMILY SSF52540 6 233 1.16E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11400 273db49a4e872acad80b29c75d7617ac 551 ProSitePatterns PS00211 ABC transporters family signature. 426 440 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 286 40.513 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 Gene3D G3DSA:3.20.20.150 1 298 1.1E-52 T 29-03-2018 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 283 3.6E-96 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 Pfam PF01261 Xylose isomerase-like TIM barrel 22 238 8.6E-35 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 SMART SM00518 3 286 4.9E-121 T 29-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 SUPERFAMILY SSF51658 2 295 1.96E-98 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 176 183 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CSW12_RS21035 6d570a61c2e8d43a855f0a2e8e8709ce 298 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 214 230 - T 29-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 Gene3D G3DSA:1.10.1520.10 18 167 4.2E-47 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 Pfam PF00035 Double-stranded RNA binding motif 175 241 2.0E-17 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 ProSitePatterns PS00517 Ribonuclease III family signature. 58 66 - T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 Pfam PF14622 Ribonuclease-III-like 32 160 3.8E-38 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 SMART SM00358 175 242 2.1E-22 T 29-03-2018 IPR014720 Double-stranded RNA-binding domain CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 22 241 6.8E-82 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 Gene3D G3DSA:3.30.160.20 169 245 1.8E-23 T 29-03-2018 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 SUPERFAMILY SSF54768 131 241 1.51E-24 T 29-03-2018 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 SUPERFAMILY SSF69065 15 177 2.27E-54 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 SMART SM00535 34 169 2.6E-60 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS08530 fb68139ee259d26026f4e20bbacc3075 245 Hamap MF_00104 Ribonuclease 3 [rnc]. 22 238 32.024 T 29-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CSW12_RS12845 1ca794ebdece50edf3f134c7025178bb 445 Gene3D G3DSA:3.30.465.10 87 210 7.6E-30 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS12845 1ca794ebdece50edf3f134c7025178bb 445 Gene3D G3DSA:3.30.43.10 10 86 4.1E-20 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS12845 1ca794ebdece50edf3f134c7025178bb 445 Pfam PF01565 FAD binding domain 35 169 4.1E-27 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS12845 1ca794ebdece50edf3f134c7025178bb 445 SUPERFAMILY SSF56176 9 201 1.82E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS12845 1ca794ebdece50edf3f134c7025178bb 445 Pfam PF08031 Berberine and berberine like 399 443 7.8E-21 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CSW12_RS08705 896d9d9aacae5d92b54abb08660d3196 90 SUPERFAMILY SSF64376 4 87 1.7E-28 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CSW12_RS08705 896d9d9aacae5d92b54abb08660d3196 90 Gene3D G3DSA:3.30.1230.10 1 90 2.6E-30 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CSW12_RS08705 896d9d9aacae5d92b54abb08660d3196 90 Pfam PF04296 Protein of unknown function (DUF448) 9 81 8.2E-28 T 29-03-2018 IPR007393 Domain of unknown function DUF448 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 SUPERFAMILY SSF52954 279 401 1.23E-33 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 SMART SM00946 409 476 4.7E-31 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 105 269 9.5E-20 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 409 476 8.7E-23 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Gene3D G3DSA:3.30.930.10 1 297 7.7E-71 T 29-03-2018 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 476 1.9E-189 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 SUPERFAMILY SSF64586 404 476 1.02E-22 T 29-03-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Gene3D G3DSA:3.30.110.30 407 475 2.1E-23 T 29-03-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Hamap MF_01571 Proline--tRNA ligase [proS]. 9 476 44.86 T 29-03-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Pfam PF03129 Anticodon binding domain 291 381 1.5E-20 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 SUPERFAMILY SSF55681 13 277 5.5E-81 T 29-03-2018 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 4.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 4.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 147 158 4.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 PRINTS PR01046 Prolyl-tRNA synthetase signature 67 85 4.1E-10 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS00880 d4d13e8ff3c1ea372d839e33d552a589 476 Gene3D G3DSA:3.40.50.800 298 406 1.6E-34 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SUPERFAMILY SSF52075 560 679 2.48E-22 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SUPERFAMILY SSF81296 689 760 4.29E-10 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00725 44 168 6.9E-18 T 29-03-2018 IPR006635 NEAT domain CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 283 304 31.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 349 370 12.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 393 414 460.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 305 326 91.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 609 630 390.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 371 392 280.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 261 282 49.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 415 436 36.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00365 327 348 41.0 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:2.60.40.1220 688 759 4.0E-16 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:2.60.40.1220 450 522 4.9E-18 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SUPERFAMILY SSF58104 763 911 8.76E-6 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Pfam PF05031 Iron Transport-associated domain 44 162 1.9E-30 T 29-03-2018 IPR006635 NEAT domain CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Pfam PF08191 LRR adjacent 481 522 0.2 T 29-03-2018 IPR012569 Leucine-rich repeat-containing adjacent domain CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Pfam PF08191 LRR adjacent 716 758 0.004 T 29-03-2018 IPR012569 Leucine-rich repeat-containing adjacent domain CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 935 966 3.6E-4 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:3.80.10.10 337 449 9.0E-19 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00369 393 413 120.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00369 653 676 110.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00369 631 652 52.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00369 261 283 160.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00369 327 349 80.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SMART SM00369 415 438 59.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:1.10.287.950 761 830 0.0087 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SUPERFAMILY SSF52058 216 433 1.03E-39 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:3.80.10.10 174 336 2.3E-26 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:3.80.10.10 523 687 2.0E-23 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 Gene3D G3DSA:1.20.1480.30 831 931 2.6E-4 T 29-03-2018 CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SUPERFAMILY SSF81296 450 524 5.6E-11 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS01470 95b05fd594ec79c164c1da7df3c20003 970 SUPERFAMILY SSF158911 46 162 1.7E-29 T 29-03-2018 CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 Gene3D G3DSA:3.30.70.270 135 340 1.7E-30 T 29-03-2018 CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 59 422 3.7E-104 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 Pfam PF13655 N-terminal domain of reverse transcriptase 16 98 3.4E-27 T 29-03-2018 IPR025960 Reverse transcriptase, N-terminal domain CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 Gene3D G3DSA:3.40.1800.10 497 569 3.1E-13 T 29-03-2018 CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 SUPERFAMILY SSF56672 54 428 1.9E-45 T 29-03-2018 CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 116 340 4.0E-43 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 SMART SM00507 502 556 6.0E-11 T 29-03-2018 IPR003615 HNH nuclease CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 Pfam PF08388 Group II intron, maturase-specific domain 359 437 3.4E-18 T 29-03-2018 IPR013597 Group II intron, maturase-specific CSW12_RS31165 5341156ef20757e66e976080d54d538f 608 Pfam PF01844 HNH endonuclease 515 560 5.0E-9 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 Gene3D G3DSA:3.40.50.720 9 267 7.3E-58 T 29-03-2018 CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 2.7E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 2.7E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 2.7E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 2.7E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 2.7E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 116 2.7E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 SUPERFAMILY SSF51735 15 265 1.06E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 265 6.9E-43 T 29-03-2018 CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 105 116 2.8E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 2.8E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28315 de7412f8916e7e2498f3cbace0b2ed7f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 2.8E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20355 ec4f989544c6f2fe792f1efd7650be2d 234 Gene3D G3DSA:3.30.240.20 181 234 5.2E-8 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS20355 ec4f989544c6f2fe792f1efd7650be2d 234 Pfam PF04239 Protein of unknown function (DUF421) 98 211 8.4E-27 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CSW12_RS20355 ec4f989544c6f2fe792f1efd7650be2d 234 Gene3D G3DSA:3.30.240.20 92 161 6.6E-20 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS26560 ef7b0315e07b6f2ec9a40386ce0b6826 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 285 330 2.0E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26560 ef7b0315e07b6f2ec9a40386ce0b6826 376 Gene3D G3DSA:3.30.565.10 242 367 3.3E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26560 ef7b0315e07b6f2ec9a40386ce0b6826 376 Pfam PF07730 Histidine kinase 178 241 2.0E-19 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS26560 ef7b0315e07b6f2ec9a40386ce0b6826 376 SUPERFAMILY SSF55874 245 364 2.75E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07480 75dc82a54ba504b93d8a8a3f16b86990 110 Pfam PF13077 Protein of unknown function (DUF3909) 1 108 2.6E-69 T 29-03-2018 IPR025073 Protein of unknown function DUF3909 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 63 712 8.8E-250 T 29-03-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SUPERFAMILY SSF50249 212 629 4.11E-149 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SMART SM00316 630 712 3.6E-19 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Gene3D G3DSA:1.10.10.10 6 65 1.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Pfam PF00773 RNB domain 252 580 5.9E-113 T 29-03-2018 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 TIGRFAM TIGR02063 RNase_R: ribonuclease R 11 712 1.1E-285 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Hamap MF_01895 Ribonuclease R [rnr]. 27 712 60.827 T 29-03-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SUPERFAMILY SSF50249 130 229 3.94E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 ProSitePatterns PS01175 Ribonuclease II family signature. 549 573 - T 29-03-2018 IPR022966 Ribonuclease II/R, conserved site CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SUPERFAMILY SSF50249 57 139 3.94E-17 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Gene3D G3DSA:2.40.50.140 629 713 1.1E-22 T 29-03-2018 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SUPERFAMILY SSF50249 630 710 2.33E-23 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SMART SM00955 252 582 1.1E-179 T 29-03-2018 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SMART SM00357 75 137 2.1E-12 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 SMART SM00357 139 206 0.0078 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Gene3D G3DSA:2.40.50.140 121 288 0.0082 T 29-03-2018 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Pfam PF00575 S1 RNA binding domain 629 711 1.1E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Pfam PF08206 Ribonuclease B OB domain 151 205 2.0E-7 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CSW12_RS25310 0a1802307d5a50284edb93414fcdf51d 812 Pfam PF08206 Ribonuclease B OB domain 76 136 2.0E-21 T 29-03-2018 IPR013223 Ribonuclease B, N-terminal OB domain CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 Gene3D G3DSA:2.160.10.10 240 375 7.8E-23 T 29-03-2018 CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 Pfam PF00483 Nucleotidyl transferase 2 230 6.2E-50 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 Gene3D G3DSA:3.90.550.10 1 239 5.8E-59 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 298 5.1E-6 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 393 507 1.7E-8 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 SUPERFAMILY SSF51161 199 370 1.11E-27 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 SUPERFAMILY SSF53738 387 516 3.88E-6 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 Gene3D G3DSA:3.40.120.10 376 525 2.0E-7 T 29-03-2018 CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 SUPERFAMILY SSF53448 262 278 1.08E-75 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS20945 04fbb9f167416c6c6d813b1ae6d764be 784 SUPERFAMILY SSF53448 1 234 1.08E-75 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS11380 54aec7c2072b7efccbf85fa3ae999ad4 159 Gene3D G3DSA:3.50.30.40 1 159 6.7E-44 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CSW12_RS11380 54aec7c2072b7efccbf85fa3ae999ad4 159 Pfam PF03737 Aldolase/RraA 4 152 1.4E-41 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CSW12_RS11380 54aec7c2072b7efccbf85fa3ae999ad4 159 TIGRFAM TIGR01935 NOT-MenG: RraA family 4 153 5.3E-54 T 29-03-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 CSW12_RS11380 54aec7c2072b7efccbf85fa3ae999ad4 159 SUPERFAMILY SSF89562 3 157 2.49E-43 T 29-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 303 6.3E-119 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 SMART SM00849 18 270 3.1E-4 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 Pfam PF00753 Metallo-beta-lactamase superfamily 26 98 1.9E-9 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 SUPERFAMILY SSF56281 2 305 1.26E-85 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 Pfam PF12706 Beta-lactamase superfamily domain 203 271 5.7E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 Gene3D G3DSA:3.60.15.10 1 307 2.1E-62 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20250 1f58e9930a9c1fa2b1ddd3a35e5ffd14 307 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 42.021 T 29-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CSW12_RS10295 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS10295 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS07085 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS07085 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS20280 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS20280 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS18665 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS18665 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS05270 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS05270 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS14155 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS14155 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS21370 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS21370 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS12120 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS12120 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS02235 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS02235 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS14495 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS14495 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS05300 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS05300 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS15355 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS15355 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS20790 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS20790 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS22865 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS22865 3e79926d51759b5be1cb536cb39ab891 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS03740 4cfcf83f4c12339acdf8de5061802aa1 489 Pfam PF00916 Sulfate permease family 8 134 2.7E-25 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS03740 4cfcf83f4c12339acdf8de5061802aa1 489 Pfam PF00916 Sulfate permease family 140 359 1.6E-39 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS03740 4cfcf83f4c12339acdf8de5061802aa1 489 Pfam PF01740 STAS domain 402 473 1.3E-6 T 29-03-2018 IPR002645 STAS domain CSW12_RS03740 4cfcf83f4c12339acdf8de5061802aa1 489 SUPERFAMILY SSF52091 400 476 1.82E-11 T 29-03-2018 IPR002645 STAS domain CSW12_RS03740 4cfcf83f4c12339acdf8de5061802aa1 489 Gene3D G3DSA:3.30.750.24 397 480 1.5E-8 T 29-03-2018 IPR002645 STAS domain CSW12_RS21520 6dd24e9648d3c6ffdcdfb19de580c3ba 218 Pfam PF07423 Protein of unknown function (DUF1510) 5 217 2.2E-69 T 29-03-2018 IPR009988 Protein of unknown function DUF1510 CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 SUPERFAMILY SSF53187 6 197 1.61E-60 T 29-03-2018 CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 SUPERFAMILY SSF53187 337 420 1.61E-60 T 29-03-2018 CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 411 3.5E-118 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 Gene3D G3DSA:3.30.70.360 188 325 3.0E-19 T 29-03-2018 CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 SUPERFAMILY SSF55031 215 308 1.26E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 Pfam PF01546 Peptidase family M20/M25/M40 86 417 6.9E-30 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 Gene3D G3DSA:3.40.630.10 8 187 6.9E-34 T 29-03-2018 CSW12_RS01070 fdd9690bc6a7da901b1da22effb93179 424 Pfam PF07687 Peptidase dimerisation domain 188 309 1.2E-30 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 469 4.0E-25 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 4.0E-25 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 4.0E-25 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 4.0E-25 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 322 336 4.0E-25 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 171 185 4.0E-25 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF81653 128 224 1.96E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 29 697 39.605 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF56784 452 576 5.89E-41 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF56784 380 421 5.89E-41 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF56784 310 334 5.89E-41 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 324 330 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 Pfam PF00702 haloacid dehalogenase-like hydrolase 318 547 7.6E-37 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 Gene3D G3DSA:2.70.150.10 6 225 1.8E-27 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 Pfam PF00122 E1-E2 ATPase 126 301 9.2E-35 T 29-03-2018 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF81665 225 316 4.05E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF81665 52 123 4.05E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 SUPERFAMILY SSF81665 590 678 4.05E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 Gene3D G3DSA:3.40.1110.10 333 460 1.5E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 Gene3D G3DSA:3.40.50.1000 461 589 1.3E-36 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 25 693 0.0 T 29-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 347 3.4E-32 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS03030 4f4c0f913d0cca140be17b8f870cc79a 697 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 385 618 6.1E-48 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PIRSF PIRSF002133 1 137 1.8E-49 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 2.6E-68 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 Gene3D G3DSA:2.40.50.140 1 140 1.3E-64 T 29-03-2018 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 9.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 9.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 9.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 9.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 9.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 9.6E-59 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 SUPERFAMILY SSF50249 2 137 1.37E-49 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.775 T 29-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27955 f9858db140009cfbdfdc3d4864a3f9b3 140 Pfam PF00164 Ribosomal protein S12/S23 32 136 1.8E-38 T 29-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS00495 fdaad1ec16680603bb80331d87564ecc 329 Pfam PF01207 Dihydrouridine synthase (Dus) 15 317 9.3E-50 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CSW12_RS00495 fdaad1ec16680603bb80331d87564ecc 329 Gene3D G3DSA:3.20.20.70 11 249 2.6E-34 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS00495 fdaad1ec16680603bb80331d87564ecc 329 Gene3D G3DSA:1.10.1200.80 250 329 9.4E-15 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CSW12_RS00495 fdaad1ec16680603bb80331d87564ecc 329 PIRSF PIRSF006621 1 328 4.7E-84 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CSW12_RS00495 fdaad1ec16680603bb80331d87564ecc 329 SUPERFAMILY SSF51395 13 319 6.11E-59 T 29-03-2018 CSW12_RS00495 fdaad1ec16680603bb80331d87564ecc 329 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CSW12_RS10915 e4926568b35b4716c83928f1a4d0ef41 353 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 221 3.3E-6 T 29-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CSW12_RS10915 e4926568b35b4716c83928f1a4d0ef41 353 Gene3D G3DSA:3.30.360.10 135 338 6.1E-26 T 29-03-2018 CSW12_RS10915 e4926568b35b4716c83928f1a4d0ef41 353 SUPERFAMILY SSF51735 3 197 1.97E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10915 e4926568b35b4716c83928f1a4d0ef41 353 Gene3D G3DSA:3.40.50.720 1 134 2.2E-33 T 29-03-2018 CSW12_RS10915 e4926568b35b4716c83928f1a4d0ef41 353 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 120 1.3E-24 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CSW12_RS03495 9a7a6cd3b9a192724e8ce37a64a5b973 151 SUPERFAMILY SSF55729 1 149 7.2E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS03495 9a7a6cd3b9a192724e8ce37a64a5b973 151 Gene3D G3DSA:3.40.630.30 1 145 5.3E-18 T 29-03-2018 CSW12_RS03495 9a7a6cd3b9a192724e8ce37a64a5b973 151 Pfam PF00583 Acetyltransferase (GNAT) family 40 116 3.0E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 SUPERFAMILY SSF53756 2 362 2.92E-110 T 29-03-2018 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 35.011 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 Gene3D G3DSA:3.40.50.2000 178 346 1.3E-30 T 29-03-2018 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 Gene3D G3DSA:3.40.50.2000 1 177 1.5E-40 T 29-03-2018 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 142 1.9E-47 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 357 3.9E-101 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS08205 05a6ba51d54ecc8a6c5c667f521a0a73 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 189 353 8.4E-43 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CSW12_RS03170 501eb974810955076ee8c9be602262dc 443 Gene3D G3DSA:3.30.70.1340 26 78 5.9E-4 T 29-03-2018 CSW12_RS03170 501eb974810955076ee8c9be602262dc 443 Gene3D G3DSA:1.20.5.320 90 204 0.027 T 29-03-2018 CSW12_RS03170 501eb974810955076ee8c9be602262dc 443 Gene3D G3DSA:1.10.287.510 234 431 0.0098 T 29-03-2018 CSW12_RS25920 d77a69cf851c2df61b621d919f4d8328 294 Pfam PF01063 Amino-transferase class IV 39 259 1.1E-44 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS25920 d77a69cf851c2df61b621d919f4d8328 294 Gene3D G3DSA:3.20.10.10 130 290 4.5E-44 T 29-03-2018 CSW12_RS25920 d77a69cf851c2df61b621d919f4d8328 294 Gene3D G3DSA:3.30.470.10 4 127 1.8E-23 T 29-03-2018 CSW12_RS25920 d77a69cf851c2df61b621d919f4d8328 294 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 11 285 1.3E-101 T 29-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CSW12_RS25920 d77a69cf851c2df61b621d919f4d8328 294 SUPERFAMILY SSF56752 22 286 1.27E-76 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS25920 d77a69cf851c2df61b621d919f4d8328 294 ProSitePatterns PS00770 Aminotransferases class-IV signature. 187 216 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS17470 743754fb9893350f6a02dd63fa82f25f 281 PIRSF PIRSF006483 1 275 3.6E-67 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS17470 743754fb9893350f6a02dd63fa82f25f 281 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 267 3.6E-12 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS17470 743754fb9893350f6a02dd63fa82f25f 281 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 209 1.0E-54 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 Gene3D G3DSA:1.10.260.40 2 105 3.7E-16 T 29-03-2018 CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 Pfam PF12844 Helix-turn-helix domain 9 67 8.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 Gene3D G3DSA:1.25.40.10 106 213 3.9E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 SUPERFAMILY SSF47413 5 65 2.57E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 SUPERFAMILY SSF48452 115 273 1.17E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 SMART SM00530 9 63 5.8E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS04190 847d22661bfd97aeba7045f35479a3a3 297 Gene3D G3DSA:1.25.40.10 214 273 1.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS15750 78b190446443c1b7f796082e0dc4f05e 427 PIRSF PIRSF006351 1 425 3.6E-149 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS15750 78b190446443c1b7f796082e0dc4f05e 427 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 17 418 8.6E-121 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CSW12_RS15750 78b190446443c1b7f796082e0dc4f05e 427 Pfam PF02378 Phosphotransferase system, EIIC 29 344 1.4E-57 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS22155 efe1e0035b2529eb38e680ea101c3769 264 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 187 204 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CSW12_RS22155 efe1e0035b2529eb38e680ea101c3769 264 Gene3D G3DSA:1.20.1070.10 156 251 0.04 T 29-03-2018 CSW12_RS22155 efe1e0035b2529eb38e680ea101c3769 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 219 5.5E-25 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 Gene3D G3DSA:1.10.287.180 6 78 3.3E-33 T 29-03-2018 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 SUPERFAMILY SSF54534 86 157 1.18E-21 T 29-03-2018 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 9.4E-33 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 32.628 T 29-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 158 2.3E-27 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 PIRSF PIRSF006092 1 158 1.8E-53 T 29-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 SUPERFAMILY SSF46557 5 79 1.02E-27 T 29-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 29-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 1.7E-58 T 29-03-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CSW12_RS21530 72e90fc55b676fc9cff0307f08d622ef 158 Gene3D G3DSA:3.10.50.30 79 158 2.0E-26 T 29-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CSW12_RS13110 95388dd6e061bf70b06bd34d2b7a85f7 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 4.3E-19 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13110 95388dd6e061bf70b06bd34d2b7a85f7 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 6.1E-24 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 176 3.2E-21 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 SMART SM00478 46 197 8.0E-57 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 Gene3D G3DSA:1.10.340.30 28 124 6.3E-32 T 29-03-2018 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 Gene3D G3DSA:1.10.1670.10 125 232 9.9E-35 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 SUPERFAMILY SSF48150 11 229 1.0E-75 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 Pfam PF00633 Helix-hairpin-helix motif 107 135 1.6E-5 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 Gene3D G3DSA:3.90.79.10 236 365 7.5E-17 T 29-03-2018 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 13 282 7.4E-110 T 29-03-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 SUPERFAMILY SSF55811 236 357 4.87E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 Pfam PF14815 NUDIX domain 243 356 1.5E-18 T 29-03-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CSW12_RS01215 947ae124ad858d4e5bd849b99ffb0913 365 SMART SM00525 198 218 0.0012 T 29-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 SUPERFAMILY SSF47384 107 190 1.96E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 SUPERFAMILY SSF55874 180 344 2.75E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 Pfam PF00512 His Kinase A (phospho-acceptor) domain 124 189 2.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 Gene3D G3DSA:3.30.565.10 194 348 9.6E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 6.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 343 6.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 6.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 324 6.3E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 SUPERFAMILY SSF158472 76 121 1.22E-5 T 29-03-2018 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 Gene3D G3DSA:1.10.287.130 114 185 6.3E-18 T 29-03-2018 CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 SMART SM00387 234 346 2.0E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 343 6.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18060 8aa5c6e300879fe0aaa916d79a64418f 348 SMART SM00388 124 190 6.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS18915 868a675429aac3299718b43bf0650b89 184 SUPERFAMILY SSF52833 43 183 4.73E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS18915 868a675429aac3299718b43bf0650b89 184 Gene3D G3DSA:3.40.30.10 23 184 4.7E-40 T 29-03-2018 CSW12_RS18915 868a675429aac3299718b43bf0650b89 184 Pfam PF00578 AhpC/TSA family 46 162 3.7E-26 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS18915 868a675429aac3299718b43bf0650b89 184 ProSitePatterns PS00194 Thioredoxin family active site. 74 92 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 SMART SM00287 225 279 0.0011 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 SMART SM00287 286 343 0.27 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 Gene3D G3DSA:3.20.20.80 1 203 5.3E-61 T 29-03-2018 CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 Pfam PF08239 Bacterial SH3 domain 234 277 1.6E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 SMART SM00641 9 113 4.4E-20 T 29-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 Pfam PF01183 Glycosyl hydrolases family 25 12 190 1.7E-57 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 Gene3D G3DSA:2.40.50.110 281 344 5.4E-9 T 29-03-2018 CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 Gene3D G3DSA:2.40.50.110 213 280 9.4E-12 T 29-03-2018 CSW12_RS09360 9d4c604e31ca055fef5934daee8911fb 348 SUPERFAMILY SSF51445 7 197 3.37E-57 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 SMART SM00382 362 554 5.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 SUPERFAMILY SSF90123 7 318 3.14E-73 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 SUPERFAMILY SSF52540 327 573 7.78E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 Pfam PF00664 ABC transporter transmembrane region 19 291 3.5E-50 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 Gene3D G3DSA:3.40.50.300 324 578 1.6E-68 T 29-03-2018 CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 Pfam PF00005 ABC transporter 353 501 1.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09350 c101a521a1beeca5b4bac112b5a6893f 583 Gene3D G3DSA:1.20.1560.10 1 323 1.0E-62 T 29-03-2018 CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 167 8.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 8.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 8.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 110 199 3.6E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 Gene3D G3DSA:3.40.50.1000 1 230 2.6E-30 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 207 8.5E-28 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00440 0bfc98514f02e5a74996262d07c26be7 247 SUPERFAMILY SSF56784 1 231 9.06E-44 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 Pfam PF01008 Initiation factor 2 subunit family 47 336 5.5E-84 T 29-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 5 347 39.08 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 336 3.3E-116 T 29-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 Gene3D G3DSA:1.20.120.420 6 147 1.6E-51 T 29-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 SUPERFAMILY SSF100950 7 342 9.77E-121 T 29-03-2018 CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 Gene3D G3DSA:3.40.50.10470 148 347 8.0E-65 T 29-03-2018 CSW12_RS00565 0ea13d4e173e7d8a94c19a37f4947b70 348 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 3.5E-137 T 29-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CSW12_RS21850 5fcd4015d330b583100b802295c75fb3 114 Pfam PF04327 Cysteine protease Prp 1 105 3.4E-25 T 29-03-2018 IPR007422 Cysteine protease Prp CSW12_RS21850 5fcd4015d330b583100b802295c75fb3 114 SUPERFAMILY SSF118010 1 110 1.7E-30 T 29-03-2018 IPR007422 Cysteine protease Prp CSW12_RS21850 5fcd4015d330b583100b802295c75fb3 114 Gene3D G3DSA:3.30.70.1490 2 111 5.7E-30 T 29-03-2018 IPR007422 Cysteine protease Prp CSW12_RS12085 97262b7722fe820db388b02f12a138b5 512 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 309 461 1.3E-4 T 29-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal CSW12_RS12085 97262b7722fe820db388b02f12a138b5 512 SUPERFAMILY SSF53474 392 505 3.06E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12085 97262b7722fe820db388b02f12a138b5 512 SUPERFAMILY SSF53474 180 356 3.06E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12085 97262b7722fe820db388b02f12a138b5 512 Gene3D G3DSA:3.40.50.1820 179 508 2.7E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12085 97262b7722fe820db388b02f12a138b5 512 Pfam PF13026 Protein of unknown function (DUF3887) 98 188 2.4E-10 T 29-03-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:3.40.50.300 297 524 4.2E-37 T 29-03-2018 CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Pfam PF14490 Helix-hairpin-helix containing domain 156 247 5.1E-29 T 29-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:1.10.150.280 100 226 1.7E-5 T 29-03-2018 CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 14 753 29.633 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Gene3D G3DSA:3.40.50.300 525 737 1.3E-28 T 29-03-2018 CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Pfam PF13538 UvrD-like helicase C-terminal domain 676 724 3.7E-16 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 SUPERFAMILY SSF52540 335 729 1.89E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 20 750 9.2E-246 T 29-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CSW12_RS21605 e8460e10d5096bed29650ceff1bc54bf 778 Pfam PF13604 AAA domain 341 548 1.2E-49 T 29-03-2018 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 267 22.587 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 265 1.7E-67 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 PIRSF PIRSF000193 4 267 3.1E-67 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 2.1E-18 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 Gene3D G3DSA:1.10.3730.10 162 266 3.3E-29 T 29-03-2018 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 265 1.5E-30 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 Gene3D G3DSA:3.40.50.720 3 161 7.4E-25 T 29-03-2018 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 SUPERFAMILY SSF48179 164 265 2.72E-26 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS28430 b2ba9d65d3c3cb7b56d852ddd713f0ea 267 SUPERFAMILY SSF51735 6 158 2.25E-28 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 SUPERFAMILY SSF50615 10 94 7.46E-31 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.2E-20 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Gene3D G3DSA:3.40.50.300 83 364 3.8E-121 T 29-03-2018 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Gene3D G3DSA:1.20.150.20 373 498 2.8E-49 T 29-03-2018 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 3.2E-258 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Gene3D G3DSA:2.40.30.20 3 82 8.4E-38 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 SUPERFAMILY SSF47917 372 500 1.62E-46 T 29-03-2018 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 SUPERFAMILY SSF52540 95 370 2.42E-99 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 2.0E-73 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 PIRSF PIRSF039088 1 501 5.8E-251 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 486 7.7E-46 T 29-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26315 59490b5ed1ba78e69cd7d6d32dcf4bce 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.655 T 29-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 SUPERFAMILY SSF47384 200 271 5.49E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 SMART SM00388 209 273 3.8E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 SUPERFAMILY SSF55874 263 420 2.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 314 419 8.7E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 270 8.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 6.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 6.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 6.5E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 Gene3D G3DSA:3.30.565.10 272 424 1.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 SMART SM00387 314 421 2.8E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07695 6f33dd0b3d2096dcbb2b998833504dd1 424 Gene3D G3DSA:1.10.287.130 194 269 1.2E-13 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 Gene3D G3DSA:1.20.1250.20 8 198 1.5E-37 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 490 3.1E-83 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 Pfam PF07690 Major Facilitator Superfamily 15 406 2.1E-58 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 SUPERFAMILY SSF103473 468 498 6.15E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 SUPERFAMILY SSF103473 9 199 6.15E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 SUPERFAMILY SSF103473 246 416 6.15E-73 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 Gene3D G3DSA:1.20.1250.20 249 504 4.3E-33 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 6.4E-6 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 355 375 6.4E-6 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 6.4E-6 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 397 416 6.4E-6 T 29-03-2018 CSW12_RS12055 213062f4d58807b97330ad0cc3353255 507 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 6.4E-6 T 29-03-2018 CSW12_RS24545 c581a5e0041a470503af4786d9323e7d 102 Gene3D G3DSA:3.40.30.30 1 101 5.4E-41 T 29-03-2018 CSW12_RS24545 c581a5e0041a470503af4786d9323e7d 102 PIRSF PIRSF010603 1 102 8.0E-48 T 29-03-2018 IPR009190 Protein of unknown function DUF1462 CSW12_RS24545 c581a5e0041a470503af4786d9323e7d 102 Pfam PF07315 Protein of unknown function (DUF1462) 6 99 6.9E-41 T 29-03-2018 IPR009190 Protein of unknown function DUF1462 CSW12_RS24545 c581a5e0041a470503af4786d9323e7d 102 SUPERFAMILY SSF52833 2 101 3.8E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS16500 08d084efa71829f76178eb437f6f75a1 220 SMART SM00882 9 205 5.4E-61 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CSW12_RS16500 08d084efa71829f76178eb437f6f75a1 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 212 6.1E-98 T 29-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CSW12_RS16500 08d084efa71829f76178eb437f6f75a1 220 SUPERFAMILY SSF100950 6 215 6.98E-67 T 29-03-2018 CSW12_RS16500 08d084efa71829f76178eb437f6f75a1 220 Gene3D G3DSA:3.40.1080.10 6 217 1.3E-62 T 29-03-2018 CSW12_RS16500 08d084efa71829f76178eb437f6f75a1 220 Pfam PF01144 Coenzyme A transferase 10 202 3.4E-36 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CSW12_RS28680 e34e281ef3fd5f1ac3524999a1dbb214 190 SUPERFAMILY SSF144091 14 183 5.1E-37 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CSW12_RS28680 e34e281ef3fd5f1ac3524999a1dbb214 190 Gene3D G3DSA:1.20.1540.10 9 183 1.6E-35 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CSW12_RS28680 e34e281ef3fd5f1ac3524999a1dbb214 190 Pfam PF01694 Rhomboid family 43 182 2.6E-31 T 29-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CSW12_RS24715 abb7ea2181889c4b72f9a984427904fa 430 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 147 420 3.0E-75 T 29-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CSW12_RS24715 abb7ea2181889c4b72f9a984427904fa 430 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 404 1.2E-61 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CSW12_RS24715 abb7ea2181889c4b72f9a984427904fa 430 SUPERFAMILY SSF101960 11 429 3.4E-117 T 29-03-2018 CSW12_RS13640 9d24db84015d52edecbaee4044ab2fff 115 SUPERFAMILY SSF46785 9 108 3.35E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13640 9d24db84015d52edecbaee4044ab2fff 115 Gene3D G3DSA:1.10.10.10 4 114 6.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13640 9d24db84015d52edecbaee4044ab2fff 115 Pfam PF03551 Transcriptional regulator PadR-like family 19 84 1.5E-17 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS11135 efc235b8d999230b4e3ba5c2777ecb6f 397 Gene3D G3DSA:1.20.1250.20 3 189 1.3E-21 T 29-03-2018 CSW12_RS11135 efc235b8d999230b4e3ba5c2777ecb6f 397 Pfam PF07690 Major Facilitator Superfamily 12 302 1.1E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS11135 efc235b8d999230b4e3ba5c2777ecb6f 397 Gene3D G3DSA:1.20.1250.20 196 384 3.1E-24 T 29-03-2018 CSW12_RS11135 efc235b8d999230b4e3ba5c2777ecb6f 397 SUPERFAMILY SSF103473 9 381 1.7E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 Gene3D G3DSA:3.10.170.10 267 426 2.5E-47 T 29-03-2018 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 124 174 1.6E-11 T 29-03-2018 IPR011096 FTP domain CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 Pfam PF03413 Peptidase propeptide and YPEB domain 189 261 8.2E-12 T 29-03-2018 IPR025711 PepSY domain CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 377 397 5.3E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 413 429 5.3E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 505 521 5.3E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 434 445 5.3E-26 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 425 590 1.2E-59 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 Gene3D G3DSA:1.10.390.10 427 591 2.5E-50 T 29-03-2018 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 SUPERFAMILY SSF55486 267 591 1.83E-89 T 29-03-2018 CSW12_RS25005 47dbccff61145c1afd04275ce31db101 591 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 268 422 5.7E-45 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CSW12_RS06285 3eaaf7d1e8f8dfcc225f18cb77b96428 192 Gene3D G3DSA:3.40.630.30 1 190 6.5E-24 T 29-03-2018 CSW12_RS06285 3eaaf7d1e8f8dfcc225f18cb77b96428 192 SUPERFAMILY SSF55729 2 183 2.13E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06285 3eaaf7d1e8f8dfcc225f18cb77b96428 192 Pfam PF00583 Acetyltransferase (GNAT) family 36 165 1.5E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS01745 52985610d86a2e856ea861f699458671 392 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.2E-20 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS01745 52985610d86a2e856ea861f699458671 392 Pfam PF07670 Nucleoside recognition 91 188 1.0E-5 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS01745 52985610d86a2e856ea861f699458671 392 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 391 5.9E-58 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 9.9E-149 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 Gene3D G3DSA:1.10.8.60 185 255 2.3E-30 T 29-03-2018 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 SMART SM00382 52 183 5.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 175.253 T 29-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 SUPERFAMILY SSF46785 257 331 5.71E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 SUPERFAMILY SSF52540 21 253 1.88E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 Gene3D G3DSA:1.10.10.10 258 328 4.1E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 Gene3D G3DSA:3.40.50.300 19 182 8.5E-31 T 29-03-2018 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 3.2E-34 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 251 332 2.0E-41 T 29-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CSW12_RS21740 14829dc41869d8550f0e6026fd1a03c9 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 5.3E-118 T 29-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 264 131.557 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 86 201 1.7E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 SUPERFAMILY SSF56784 2 255 2.81E-66 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 Gene3D G3DSA:1.10.150.240 21 90 6.5E-31 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 2 254 4.3E-116 T 29-03-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 Gene3D G3DSA:3.40.50.1000 91 261 1.8E-29 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 195 7.8E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS06170 c5ba9de2780208e288af67421c349a24 264 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 1.1E-17 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 2.4E-26 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 SUPERFAMILY SSF55920 83 348 9.03E-85 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 Pfam PF00557 Metallopeptidase family M24 136 336 7.1E-68 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 Gene3D G3DSA:3.40.350.10 1 110 1.7E-27 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 6.3E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 6.3E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 185 198 6.3E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 SUPERFAMILY SSF53092 2 125 2.09E-23 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CSW12_RS20580 82a96fd89f78d54dabbb0c189759fe7e 353 Gene3D G3DSA:3.90.230.10 111 352 2.4E-82 T 29-03-2018 CSW12_RS21555 e6ad5d503918847768912361923ee872 356 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 13 355 2.0E-98 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CSW12_RS21555 e6ad5d503918847768912361923ee872 356 Gene3D G3DSA:3.30.160.60 324 356 6.2E-10 T 29-03-2018 CSW12_RS21555 e6ad5d503918847768912361923ee872 356 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 15 355 32.871 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CSW12_RS21555 e6ad5d503918847768912361923ee872 356 Gene3D G3DSA:3.30.160.60 83 113 4.9E-8 T 29-03-2018 CSW12_RS21555 e6ad5d503918847768912361923ee872 356 Pfam PF02618 YceG-like family 49 349 5.0E-78 T 29-03-2018 IPR003770 Endolytic murein transglycosylase CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Gene3D G3DSA:2.40.50.140 1 111 1.9E-27 T 29-03-2018 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 SUPERFAMILY SSF50249 4 108 7.81E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 586 4.8E-261 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 1.3E-17 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 559 2.3E-111 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 SUPERFAMILY SSF55681 426 585 6.57E-109 T 29-03-2018 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 SUPERFAMILY SSF55681 113 297 6.57E-109 T 29-03-2018 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Gene3D G3DSA:3.30.930.10 369 588 2.3E-57 T 29-03-2018 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Gene3D G3DSA:3.30.930.10 136 353 3.7E-54 T 29-03-2018 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 SUPERFAMILY SSF55261 294 421 7.85E-44 T 29-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Pfam PF02938 GAD domain 313 407 1.2E-31 T 29-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 6.1E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 6.1E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 6.1E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 6.1E-27 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS21655 f1dd17a1d64e09fee5df8f638e0bea09 591 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 34.842 T 29-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CSW12_RS03335 b83d5eb24f12272726b50456b07dfe88 367 Gene3D G3DSA:1.20.1600.10 66 287 6.4E-11 T 29-03-2018 CSW12_RS03335 b83d5eb24f12272726b50456b07dfe88 367 Pfam PF13437 HlyD family secretion protein 182 283 9.1E-8 T 29-03-2018 CSW12_RS03335 b83d5eb24f12272726b50456b07dfe88 367 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 366 5.4E-33 T 29-03-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Gene3D G3DSA:3.30.300.10 146 247 8.1E-48 T 29-03-2018 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Gene3D G3DSA:3.30.300.10 260 399 1.1E-48 T 29-03-2018 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 9.0E-70 T 29-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 SUPERFAMILY SSF55973 247 397 3.34E-70 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 58.755 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 1.1E-49 T 29-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Gene3D G3DSA:3.30.300.10 13 145 2.2E-45 T 29-03-2018 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 SUPERFAMILY SSF55973 125 246 6.28E-53 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 7.2E-44 T 29-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 PIRSF PIRSF000497 1 398 1.8E-177 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 29-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 SUPERFAMILY SSF55973 5 111 2.28E-47 T 29-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS23520 7d47a5697a63643f199938e815aebb01 399 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 2.2E-185 T 29-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CSW12_RS21125 ae6fca62d534baba9646cbb2cfe83f16 156 Pfam PF02130 Uncharacterized protein family UPF0054 13 151 6.6E-51 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CSW12_RS21125 ae6fca62d534baba9646cbb2cfe83f16 156 SUPERFAMILY SSF55486 2 155 1.42E-46 T 29-03-2018 CSW12_RS21125 ae6fca62d534baba9646cbb2cfe83f16 156 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 122 132 - T 29-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CSW12_RS21125 ae6fca62d534baba9646cbb2cfe83f16 156 Gene3D G3DSA:3.40.390.30 1 156 9.8E-53 T 29-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CSW12_RS21125 ae6fca62d534baba9646cbb2cfe83f16 156 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 156 24.703 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CSW12_RS21125 ae6fca62d534baba9646cbb2cfe83f16 156 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 152 1.3E-43 T 29-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Gene3D G3DSA:3.90.400.10 104 167 6.4E-31 T 29-03-2018 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 SUPERFAMILY SSF51445 3 475 3.36E-163 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 SMART SM00642 13 419 4.1E-171 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 553 1.1E-9 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Gene3D G3DSA:3.20.20.80 346 473 8.3E-23 T 29-03-2018 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Gene3D G3DSA:2.60.40.1180 481 558 1.2E-22 T 29-03-2018 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 SUPERFAMILY SSF51011 480 557 2.02E-21 T 29-03-2018 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Gene3D G3DSA:3.20.20.470 1 103 2.1E-37 T 29-03-2018 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Gene3D G3DSA:3.20.20.470 168 345 1.8E-39 T 29-03-2018 CSW12_RS07655 4626cc6954087344c08cfe70c3e4e444 558 Pfam PF00128 Alpha amylase, catalytic domain 28 376 1.2E-135 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 Pfam PF08544 GHMP kinases C terminal 196 272 1.3E-12 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 Pfam PF00288 GHMP kinases N terminal domain 75 135 1.8E-13 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 TIGRFAM TIGR00191 thrB: homoserine kinase 4 291 9.4E-80 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 81 92 - T 29-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 Gene3D G3DSA:3.30.230.10 2 160 2.4E-29 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 SUPERFAMILY SSF55060 156 280 2.72E-33 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 Gene3D G3DSA:3.30.70.890 161 279 1.9E-23 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 Hamap MF_00384 Homoserine kinase [thrB]. 4 289 32.043 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 PIRSF PIRSF000676 1 292 5.7E-94 T 29-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 SUPERFAMILY SSF54211 5 146 9.87E-30 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 PRINTS PR00958 Homoserine kinase signature 11 26 7.4E-40 T 29-03-2018 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 PRINTS PR00958 Homoserine kinase signature 122 135 7.4E-40 T 29-03-2018 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 PRINTS PR00958 Homoserine kinase signature 160 177 7.4E-40 T 29-03-2018 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 PRINTS PR00958 Homoserine kinase signature 88 103 7.4E-40 T 29-03-2018 CSW12_RS18010 5738748a4e6e486c27758a192c71a006 297 PRINTS PR00958 Homoserine kinase signature 240 255 7.4E-40 T 29-03-2018 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 167 188 1.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 217 240 1.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 114 140 1.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 319 338 1.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 PRINTS PR00447 Natural resistance-associated macrophage protein signature 142 161 1.4E-33 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 34 397 1.5E-125 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 19 429 38.686 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS18470 81ed3124b1aa5dba096ce6b375eb8d21 431 Pfam PF01566 Natural resistance-associated macrophage protein 55 403 1.1E-118 T 29-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 831 1186 1.9E-64 T 29-03-2018 IPR010080 Thioester reductase-like domain CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Gene3D G3DSA:3.40.50.720 831 1145 2.3E-26 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 SUPERFAMILY SSF47336 723 793 1.06E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Gene3D G3DSA:3.40.50.980 215 363 7.8E-43 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 PIRSF PIRSF001617 328 589 1.3E-22 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 PIRSF PIRSF001617 664 1133 2.7E-54 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 PIRSF PIRSF001617 80 336 1.6E-22 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 PIRSF PIRSF001617 586 673 1.4E-17 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Gene3D G3DSA:2.30.38.10 531 611 1.9E-21 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Gene3D G3DSA:1.10.1200.10 739 806 2.0E-14 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 ProSitePatterns PS00012 Phosphopantetheine attachment site. 755 770 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 SUPERFAMILY SSF56801 189 744 1.96E-148 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Pfam PF07993 Male sterility protein 834 1070 3.8E-52 T 29-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Gene3D G3DSA:3.40.50.980 364 528 2.3E-37 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Pfam PF00550 Phosphopantetheine attachment site 733 793 5.7E-7 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Pfam PF13193 AMP-binding enzyme C-terminal domain 629 702 1.6E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Pfam PF00501 AMP-binding enzyme 225 621 4.1E-98 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 Gene3D G3DSA:3.30.300.30 616 738 1.5E-32 T 29-03-2018 CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 ProSitePatterns PS00455 Putative AMP-binding domain signature. 358 369 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 244 645 8.0E-126 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS00790 25f1144ee7f94b1571f74a3f40f0c43c 1193 SUPERFAMILY SSF51735 831 1106 8.75E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26715 da307adea1ec60b14061946319cf9c07 323 Gene3D G3DSA:3.40.718.10 17 289 5.9E-65 T 29-03-2018 CSW12_RS26715 da307adea1ec60b14061946319cf9c07 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 319 1.5E-128 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CSW12_RS26715 da307adea1ec60b14061946319cf9c07 323 PIRSF PIRSF000428 1 323 2.2E-110 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CSW12_RS26715 da307adea1ec60b14061946319cf9c07 323 SUPERFAMILY SSF53659 5 322 4.52E-93 T 29-03-2018 CSW12_RS26715 da307adea1ec60b14061946319cf9c07 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 1.0E-126 T 29-03-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 Gene3D G3DSA:1.10.510.10 79 495 5.2E-57 T 29-03-2018 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 Gene3D G3DSA:3.30.200.20 2 78 7.2E-24 T 29-03-2018 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 29-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 Pfam PF00069 Protein kinase domain 11 264 1.7E-54 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 29-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 SMART SM00220 11 271 5.9E-68 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 SMART SM00740 500 566 3.3E-12 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 SMART SM00740 433 499 1.5E-5 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 SMART SM00740 365 432 3.2E-11 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 SUPERFAMILY SSF56112 7 269 3.78E-84 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 Pfam PF03793 PASTA domain 438 499 6.7E-11 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 Pfam PF03793 PASTA domain 508 565 1.7E-12 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08460 c6999fabed1cb4ed5ff01f9b13fa7007 657 Pfam PF03793 PASTA domain 369 431 3.1E-12 T 29-03-2018 IPR005543 PASTA domain CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 5 354 1.8E-174 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 PIRSF PIRSF036458 2 357 2.6E-180 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 180 197 - T 29-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 Hamap MF_00542 Probable butyrate kinase [buk]. 1 367 174.503 T 29-03-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 SUPERFAMILY SSF53067 4 173 9.72E-75 T 29-03-2018 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 180 201 3.9E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 298 314 3.9E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 6 17 3.9E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 PRINTS PR00471 Acetate kinase family signature 275 288 3.9E-17 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 SUPERFAMILY SSF53067 118 348 1.47E-56 T 29-03-2018 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 Gene3D G3DSA:3.30.420.40 3 179 6.8E-62 T 29-03-2018 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 Gene3D G3DSA:3.30.420.40 180 365 2.0E-46 T 29-03-2018 CSW12_RS20390 d1e25850d3d5af9c25064e9054e1bf85 367 Pfam PF00871 Acetokinase family 6 362 2.4E-75 T 29-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 SUPERFAMILY SSF56601 184 586 2.9E-92 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 Pfam PF00905 Penicillin binding protein transpeptidase domain 262 559 4.6E-82 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 213 8.0E-23 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 Gene3D G3DSA:3.40.710.10 235 601 7.8E-91 T 29-03-2018 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 SMART SM00740 590 649 3.0E-5 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 SMART SM00740 651 705 7.8 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 SUPERFAMILY SSF54184 650 703 7.98E-11 T 29-03-2018 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 Pfam PF03793 PASTA domain 651 703 6.0E-7 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 Pfam PF03793 PASTA domain 595 646 2.2E-8 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 SUPERFAMILY SSF56519 59 233 9.16E-39 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 SUPERFAMILY SSF54184 590 648 4.45E-12 T 29-03-2018 CSW12_RS08175 87b638a473fe6fc67489327ac53fa931 716 Gene3D G3DSA:3.90.1310.10 26 234 6.9E-35 T 29-03-2018 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 462 5.5E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 SUPERFAMILY SSF158472 188 235 1.83E-7 T 29-03-2018 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 309 2.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 SMART SM00304 187 239 8.1E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 SMART SM00387 356 464 3.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 Pfam PF00672 HAMP domain 188 234 5.3E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 Gene3D G3DSA:3.30.565.10 307 464 2.2E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 Gene3D G3DSA:3.30.450.20 28 156 2.8E-10 T 29-03-2018 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 SMART SM00388 247 312 4.0E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 SUPERFAMILY SSF55874 314 463 6.55E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 Gene3D G3DSA:1.10.287.130 237 306 1.3E-15 T 29-03-2018 CSW12_RS26070 c2a5f46b2e31f87400d3a2d65fc5e3df 476 SUPERFAMILY SSF47384 234 310 4.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 Pfam PF00664 ABC transporter transmembrane region 20 265 1.5E-24 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 18 542 1.5E-170 T 29-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 Pfam PF00005 ABC transporter 352 501 1.8E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 Gene3D G3DSA:3.40.50.300 320 572 1.6E-64 T 29-03-2018 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 SUPERFAMILY SSF90123 4 313 1.05E-46 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 Gene3D G3DSA:1.20.1560.10 7 319 2.6E-36 T 29-03-2018 CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 SMART SM00382 361 547 8.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS18145 1bed0cf15eaa819110d9b03b9a8d3aac 573 SUPERFAMILY SSF52540 328 565 3.86E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 80 181 8.6E-6 T 29-03-2018 IPR000014 PAS domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 SMART SM00387 306 412 9.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 SUPERFAMILY SSF55874 255 413 1.14E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 Pfam PF13426 PAS domain 96 183 3.0E-6 T 29-03-2018 IPR000014 PAS domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 SUPERFAMILY SSF55785 78 182 1.05E-10 T 29-03-2018 IPR000014 PAS domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 Pfam PF00512 His Kinase A (phospho-acceptor) domain 198 257 2.4E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 Gene3D G3DSA:3.30.450.20 50 190 5.6E-9 T 29-03-2018 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 409 4.8E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 SUPERFAMILY SSF47384 187 258 2.55E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 SMART SM00091 82 149 0.008 T 29-03-2018 IPR000014 PAS domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 Gene3D G3DSA:1.10.287.130 191 257 1.4E-11 T 29-03-2018 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 SMART SM00388 196 261 2.7E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 Gene3D G3DSA:3.30.565.10 261 422 1.4E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 409 9.1E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 372 9.1E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 9.1E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06880 55ea1a6221ef8ec6a12b993da553f854 423 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 9.1E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 SUPERFAMILY SSF47384 73 153 1.51E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 288 3.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 307 3.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 235 249 3.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 263 3.4E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 Gene3D G3DSA:3.30.565.10 147 307 1.2E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 SUPERFAMILY SSF55874 143 306 2.88E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 SMART SM00388 85 152 1.7E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 Pfam PF00512 His Kinase A (phospho-acceptor) domain 85 152 8.3E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 SMART SM00387 198 310 3.0E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 203 306 1.0E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22290 90f646748a4ea7f139f1af27cd11f23a 311 Gene3D G3DSA:1.10.287.130 64 146 1.0E-12 T 29-03-2018 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 SUPERFAMILY SSF50129 1 93 1.7E-35 T 29-03-2018 IPR011032 GroES-like CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 SMART SM00883 1 93 5.2E-58 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 29-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 2.9E-36 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.103 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.8E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.8E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.8E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.8E-32 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS28850 371a8eb92091ca4882053ab0b8a32e8d 94 Gene3D G3DSA:2.30.33.40 1 94 7.1E-40 T 29-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:3.40.50.740 320 418 2.7E-23 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 262 315 1.6E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:2.40.40.20 787 937 9.3E-27 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 SMART SM00929 85 126 1.9E-12 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 PIRSF PIRSF036643 1 968 0.0 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:3.30.70.20 199 266 0.068 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:2.20.25.90 267 319 5.9E-18 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Pfam PF01568 Molydopterin dinucleotide binding domain 824 931 2.0E-20 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 SUPERFAMILY SSF53706 255 788 5.89E-195 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 SUPERFAMILY SSF54862 136 218 9.42E-17 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 124 2.3E-10 T 29-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 194 205 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 266 934 4.8E-248 T 29-03-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:3.10.20.30 1 119 1.8E-12 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 77 4.9E-18 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Pfam PF12838 4Fe-4S dicluster domain 150 208 2.8E-6 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:3.30.70.20 127 198 3.9E-12 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 SMART SM00926 261 315 3.3E-18 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Pfam PF00384 Molybdopterin oxidoreductase 318 742 9.2E-88 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 SUPERFAMILY SSF54292 5 128 6.77E-32 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 SUPERFAMILY SSF50692 789 936 1.33E-34 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:3.40.228.10 419 508 7.3E-18 T 29-03-2018 CSW12_RS09890 6cfa0bb66ebe5a50e878b92742d94298 979 Gene3D G3DSA:3.40.50.740 510 786 3.7E-79 T 29-03-2018 CSW12_RS03355 f518d8216990a9f31d1d98316a0c80fe 640 Pfam PF02687 FtsX-like permease family 85 174 5.2E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS03355 f518d8216990a9f31d1d98316a0c80fe 640 PIRSF PIRSF018968 1 639 1.2E-94 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 Pfam PF00390 Malic enzyme, N-terminal domain 16 149 7.9E-31 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 Pfam PF03949 Malic enzyme, NAD binding domain 163 384 3.0E-25 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 ProSitePatterns PS00331 Malic enzymes signature. 157 173 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 SUPERFAMILY SSF51735 161 405 1.46E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 PRINTS PR00072 Malic enzyme signature 157 173 1.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 PRINTS PR00072 Malic enzyme signature 78 100 1.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 PRINTS PR00072 Malic enzyme signature 188 204 1.5E-8 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 SUPERFAMILY SSF53223 7 159 1.58E-57 T 29-03-2018 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 PIRSF PIRSF000106 37 408 2.2E-86 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 Gene3D G3DSA:3.40.50.720 159 408 2.0E-88 T 29-03-2018 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 Gene3D G3DSA:3.40.50.10380 4 158 1.8E-42 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 SMART SM01274 16 149 2.6E-86 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS22645 772ef0ba1d08e392d2b795b2d63c43ad 412 SMART SM00919 161 385 5.7E-136 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 Gene3D G3DSA:1.20.140.10 239 380 2.7E-16 T 29-03-2018 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 95 5.9E-8 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 360 7.0E-12 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 PIRSF PIRSF016578 139 381 2.2E-14 T 29-03-2018 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 PIRSF PIRSF016578 2 111 1.1E-9 T 29-03-2018 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 Gene3D G3DSA:2.40.110.10 123 224 1.7E-19 T 29-03-2018 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 SUPERFAMILY SSF47203 240 380 1.61E-21 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 SUPERFAMILY SSF56645 4 219 1.13E-37 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 217 7.8E-17 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CSW12_RS12265 8b99d71deb381b75f7849cbba0129992 382 Gene3D G3DSA:1.10.540.10 1 107 8.4E-11 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 Gene3D G3DSA:3.30.70.100 1 68 1.6E-23 T 29-03-2018 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 Pfam PF00403 Heavy-metal-associated domain 5 66 1.8E-19 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 15 28 1.4E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 54 67 1.4E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 28 41 1.4E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 PRINTS PR00944 Copper ion binding protein signature 3 15 1.4E-5 T 29-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 SUPERFAMILY SSF55008 1 67 8.9E-22 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS09135 21c47d6e30df539b813b08aecc0f20a1 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 67 1.9E-22 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CSW12_RS11730 de4e1b59a56fb2fe809954a0ae26029f 142 Pfam PF17428 Family of unknown function (DUF5412) 13 129 2.8E-42 T 29-03-2018 IPR035406 Protein of unknown function DUF5412 CSW12_RS11730 de4e1b59a56fb2fe809954a0ae26029f 142 ProDom PD049095 YRZH 103 140 1.0E-14 T 29-03-2018 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 334 345 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 Gene3D G3DSA:3.40.50.300 18 239 1.9E-95 T 29-03-2018 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 Gene3D G3DSA:3.40.50.300 240 448 4.6E-75 T 29-03-2018 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 SUPERFAMILY SSF52540 10 560 1.63E-249 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 562 49.357 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 Pfam PF01268 Formate--tetrahydrofolate ligase 8 562 1.6E-273 T 29-03-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 109 119 - T 29-03-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CSW12_RS17370 c1752cbe801b711e202859ae767c2a40 562 Gene3D G3DSA:3.10.410.10 450 538 1.8E-38 T 29-03-2018 CSW12_RS12495 55738b1e960620528dc4e15352d206eb 313 Gene3D G3DSA:3.40.710.10 2 313 1.1E-53 T 29-03-2018 CSW12_RS12495 55738b1e960620528dc4e15352d206eb 313 SUPERFAMILY SSF56601 17 310 5.07E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS12495 55738b1e960620528dc4e15352d206eb 313 Pfam PF00144 Beta-lactamase 22 294 5.0E-28 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS30645 de82b2b76016bc3184a14cc0bde75ad3 332 SUPERFAMILY SSF51735 4 319 4.47E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS30645 de82b2b76016bc3184a14cc0bde75ad3 332 Pfam PF13460 NAD(P)H-binding 10 131 6.2E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS30645 de82b2b76016bc3184a14cc0bde75ad3 332 Gene3D G3DSA:3.40.50.720 3 320 1.8E-27 T 29-03-2018 CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 Gene3D G3DSA:3.40.50.720 1 43 3.5E-9 T 29-03-2018 CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 Gene3D G3DSA:3.40.50.720 44 258 9.4E-63 T 29-03-2018 CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 SUPERFAMILY SSF51735 6 253 4.89E-83 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-13 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.4E-64 T 29-03-2018 CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23270 8d261796bba8bfb84254cbe8b6fec830 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.5E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS25205 1f0e523be3796c5fe6794f79cbb9be08 400 Gene3D G3DSA:1.20.1250.20 8 205 1.4E-19 T 29-03-2018 CSW12_RS25205 1f0e523be3796c5fe6794f79cbb9be08 400 SUPERFAMILY SSF103473 4 397 9.55E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS25205 1f0e523be3796c5fe6794f79cbb9be08 400 Gene3D G3DSA:1.20.1250.20 209 398 5.3E-14 T 29-03-2018 CSW12_RS25205 1f0e523be3796c5fe6794f79cbb9be08 400 Pfam PF07690 Major Facilitator Superfamily 17 361 4.6E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 SUPERFAMILY SSF51569 5 325 2.64E-144 T 29-03-2018 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 Gene3D G3DSA:3.20.20.70 1 327 8.1E-155 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 1.2E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 1.2E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 1.2E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.2E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 1.2E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.2E-59 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 PIRSF PIRSF001415 1 326 3.3E-155 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 29-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 322 1.4E-150 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21945 64870624a0e2154a17237905c7868e02 329 SMART SM01004 4 323 2.1E-240 T 29-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 SUPERFAMILY SSF53850 3 186 3.04E-53 T 29-03-2018 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 Gene3D G3DSA:3.30.70.260 191 281 1.4E-21 T 29-03-2018 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 Gene3D G3DSA:3.40.190.10 1 92 1.1E-30 T 29-03-2018 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 SUPERFAMILY SSF55021 178 279 7.91E-23 T 29-03-2018 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 Pfam PF00800 Prephenate dehydratase 4 185 1.2E-59 T 29-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 228 235 - T 29-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 PIRSF PIRSF001500 1 282 9.4E-68 T 29-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CSW12_RS21805 f6f173479e1324f0deeea26e2ba10ca7 283 Gene3D G3DSA:3.40.190.10 93 172 3.7E-25 T 29-03-2018 CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 ProSitePatterns PS00042 Crp-type HTH domain signature. 169 192 - T 29-03-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 SMART SM00100 3 122 5.3E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 SUPERFAMILY SSF51206 9 137 1.03E-30 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 167 183 3.2E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 198 3.2E-6 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 Gene3D G3DSA:2.60.120.10 5 131 7.0E-25 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 SUPERFAMILY SSF46785 140 223 8.65E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 SMART SM00419 161 209 1.5E-15 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 Gene3D G3DSA:1.10.10.10 132 218 3.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 Pfam PF13545 Crp-like helix-turn-helix domain 144 213 1.6E-17 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS17270 6069fcb60ad0edfcfc46ffe4e75be47c 230 Pfam PF00027 Cyclic nucleotide-binding domain 23 109 1.4E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 PIRSF PIRSF000136 1 436 4.4E-162 T 29-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 20 53 - T 29-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 Gene3D G3DSA:3.30.465.10 69 183 1.7E-25 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 SUPERFAMILY SSF56176 7 185 2.85E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 Gene3D G3DSA:3.40.462.10 184 399 2.3E-41 T 29-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 Pfam PF04030 D-arabinono-1,4-lactone oxidase 179 429 6.8E-81 T 29-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 Pfam PF01565 FAD binding domain 20 155 5.7E-29 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 Gene3D G3DSA:3.30.43.10 3 68 1.1E-17 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS02590 1ebb724bec6e15fe922b3d61f7b0fbca 438 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 9 431 5.7E-122 T 29-03-2018 CSW12_RS01550 257327b483147e0d4adfe5fe1831c213 310 Gene3D G3DSA:1.20.58.370 16 58 9.6E-6 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CSW12_RS01550 257327b483147e0d4adfe5fe1831c213 310 Gene3D G3DSA:1.10.3720.10 78 308 1.6E-42 T 29-03-2018 CSW12_RS01550 257327b483147e0d4adfe5fe1831c213 310 SUPERFAMILY SSF161098 71 298 6.15E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01550 257327b483147e0d4adfe5fe1831c213 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 305 3.4E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS17550 88f5d1fa0129bd4e8a886d238811d9ee 148 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS17550 88f5d1fa0129bd4e8a886d238811d9ee 148 Gene3D G3DSA:3.90.79.10 6 147 4.0E-17 T 29-03-2018 CSW12_RS17550 88f5d1fa0129bd4e8a886d238811d9ee 148 PRINTS PR00502 NUDIX hydrolase family signature 36 50 8.9E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS17550 88f5d1fa0129bd4e8a886d238811d9ee 148 PRINTS PR00502 NUDIX hydrolase family signature 50 65 8.9E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS17550 88f5d1fa0129bd4e8a886d238811d9ee 148 Pfam PF00293 NUDIX domain 6 139 5.9E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS17550 88f5d1fa0129bd4e8a886d238811d9ee 148 SUPERFAMILY SSF55811 2 132 5.42E-17 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 SUPERFAMILY SSF52788 1 148 4.06E-47 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 5.4E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 5.4E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 5.4E-17 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 Gene3D G3DSA:3.40.50.2300 1 154 8.2E-48 T 29-03-2018 CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 SMART SM00226 2 147 6.1E-52 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS00935 2491fa965eacfa9cdebe2d9f9b228d4f 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 145 5.3E-42 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS28350 57046258dae911a1e249287cf1e4759e 177 Pfam PF07690 Major Facilitator Superfamily 9 171 6.3E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS28350 57046258dae911a1e249287cf1e4759e 177 Gene3D G3DSA:1.20.1250.20 1 174 3.1E-21 T 29-03-2018 CSW12_RS28350 57046258dae911a1e249287cf1e4759e 177 SUPERFAMILY SSF103473 8 172 1.16E-24 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS09480 f27f4a5cc0e27c193c11268642f7d965 322 SUPERFAMILY SSF53335 58 223 9.14E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS09480 f27f4a5cc0e27c193c11268642f7d965 322 Pfam PF08241 Methyltransferase domain 104 196 4.8E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS09480 f27f4a5cc0e27c193c11268642f7d965 322 Gene3D G3DSA:3.40.50.150 57 264 3.7E-26 T 29-03-2018 CSW12_RS09480 f27f4a5cc0e27c193c11268642f7d965 322 Gene3D G3DSA:1.10.1220.10 5 56 4.1E-4 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 SMART SM01060 8 391 1.8E-277 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 Gene3D G3DSA:2.40.180.10 1 358 1.8E-165 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 Pfam PF06628 Catalase-related immune-responsive 414 475 2.5E-18 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 Pfam PF00199 Catalase 8 387 2.4E-190 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PIRSF PIRSF038928 1 481 3.9E-200 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 SUPERFAMILY SSF56634 3 483 1.96E-210 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PRINTS PR00067 Catalase signature 124 142 1.7E-75 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PRINTS PR00067 Catalase signature 289 316 1.7E-75 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PRINTS PR00067 Catalase signature 321 347 1.7E-75 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PRINTS PR00067 Catalase signature 84 102 1.7E-75 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PRINTS PR00067 Catalase signature 21 44 1.7E-75 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS05280 55cfd44a5c314a885798d4d23521ca47 488 PRINTS PR00067 Catalase signature 105 122 1.7E-75 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 Gene3D G3DSA:2.40.10.170 1 79 9.7E-32 T 29-03-2018 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 29-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 57.925 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 Gene3D G3DSA:1.10.1140.10 354 464 1.2E-44 T 29-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 SUPERFAMILY SSF52540 81 353 4.43E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 SUPERFAMILY SSF47917 351 466 7.59E-53 T 29-03-2018 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 SUPERFAMILY SSF50615 1 78 3.92E-27 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 1.1E-259 T 29-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 4.0E-26 T 29-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 2.6E-68 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 SMART SM00382 147 410 7.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26300 b889063ff10c5da6c8bb30a772352a08 468 Gene3D G3DSA:3.40.50.300 80 353 2.2E-92 T 29-03-2018 CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 Gene3D G3DSA:1.10.1660.10 1 130 4.3E-20 T 29-03-2018 CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 SUPERFAMILY SSF55136 127 271 2.62E-14 T 29-03-2018 CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 Gene3D G3DSA:3.20.80.10 131 271 6.5E-21 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 SMART SM00871 120 270 1.4E-10 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 SUPERFAMILY SSF46955 2 104 1.97E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 Pfam PF13411 MerR HTH family regulatory protein 2 71 2.9E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS10470 03a8e2be732548fea26d2e9b5cfed17a 273 SMART SM00422 2 72 5.2E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS23860 da8751145884b10a736c9e7103bc3be8 192 SUPERFAMILY SSF53335 5 168 1.89E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS23860 da8751145884b10a736c9e7103bc3be8 192 Gene3D G3DSA:3.40.50.150 2 164 1.3E-17 T 29-03-2018 CSW12_RS23860 da8751145884b10a736c9e7103bc3be8 192 Pfam PF00398 Ribosomal RNA adenine dimethylase 25 141 4.5E-11 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CSW12_RS18430 71dfd030101a893ec4b2c49858c224f3 359 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 47 223 6.0E-59 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS18430 71dfd030101a893ec4b2c49858c224f3 359 Gene3D G3DSA:1.20.1170.10 40 359 2.2E-46 T 29-03-2018 CSW12_RS18430 71dfd030101a893ec4b2c49858c224f3 359 SUPERFAMILY SSF58100 34 356 1.65E-98 T 29-03-2018 CSW12_RS16110 f6e475f6fad9b5bd7730dd7f4d20d37b 206 Gene3D G3DSA:3.30.70.100 91 174 6.5E-8 T 29-03-2018 CSW12_RS16110 f6e475f6fad9b5bd7730dd7f4d20d37b 206 SUPERFAMILY SSF54909 1 93 1.21E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS16110 f6e475f6fad9b5bd7730dd7f4d20d37b 206 Pfam PF16291 Domain of unknown function (DUF4937 2 87 3.7E-34 T 29-03-2018 IPR032555 Domain of unknown function DUF4937 CSW12_RS16110 f6e475f6fad9b5bd7730dd7f4d20d37b 206 SUPERFAMILY SSF54909 107 173 1.36E-8 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS30120 f5834a7786a286f696dce8bb29bf52d5 77 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 18 75 8.5E-21 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS30120 f5834a7786a286f696dce8bb29bf52d5 77 Gene3D G3DSA:2.30.30.100 17 77 7.3E-21 T 29-03-2018 CSW12_RS30120 f5834a7786a286f696dce8bb29bf52d5 77 SUPERFAMILY SSF50182 19 76 3.6E-15 T 29-03-2018 IPR010920 LSM domain CSW12_RS30120 f5834a7786a286f696dce8bb29bf52d5 77 Pfam PF17209 Hfq protein 19 75 8.3E-18 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS24845 b8e0a8cfcf766261797af27b05d91687 305 SUPERFAMILY SSF51730 37 300 3.57E-79 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CSW12_RS24845 b8e0a8cfcf766261797af27b05d91687 305 Gene3D G3DSA:3.20.20.220 1 305 9.1E-77 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CSW12_RS24845 b8e0a8cfcf766261797af27b05d91687 305 PIRSF PIRSF000196 1 305 2.5E-137 T 29-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CSW12_RS24845 b8e0a8cfcf766261797af27b05d91687 305 Pfam PF01619 Proline dehydrogenase 45 298 5.1E-38 T 29-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 SUPERFAMILY SSF52540 313 516 9.28E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 SUPERFAMILY SSF52540 4 240 4.17E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 Pfam PF12848 ABC transporter 226 302 6.0E-17 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 SMART SM00382 28 231 3.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 SMART SM00382 343 514 4.4E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 Gene3D G3DSA:3.40.50.300 295 553 1.2E-55 T 29-03-2018 CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 Gene3D G3DSA:3.40.50.300 1 294 1.1E-58 T 29-03-2018 CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 Pfam PF16326 ABC transporter C-terminal domain 559 624 5.3E-18 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 Pfam PF00005 ABC transporter 20 187 4.2E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS17140 05f01097df915f2eb0b687daa3d4871d 631 Pfam PF00005 ABC transporter 334 469 3.6E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 295 7.1E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Gene3D G3DSA:3.40.50.720 151 326 1.0E-18 T 29-03-2018 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 SUPERFAMILY SSF51905 10 316 1.04E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Gene3D G3DSA:3.50.50.60 3 141 5.6E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 9.9E-19 T 29-03-2018 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 9.9E-19 T 29-03-2018 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 9.9E-19 T 29-03-2018 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 9.9E-19 T 29-03-2018 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 1.8E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 68 78 1.8E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 1.8E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 1.8E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 1.8E-23 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS24420 f8a4fda0dfe8ef33c9028f37d5a50dc9 331 Hamap MF_01685 Ferredoxin--NADP reductase. 9 330 44.728 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 SUPERFAMILY SSF100950 6 224 1.47E-62 T 29-03-2018 CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 13 217 9.6E-23 T 29-03-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 SUPERFAMILY SSF100950 227 496 9.14E-87 T 29-03-2018 CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 13 496 1.5E-224 T 29-03-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 Gene3D G3DSA:3.40.1080.10 239 503 3.7E-61 T 29-03-2018 CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 322 465 5.0E-44 T 29-03-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain CSW12_RS18550 2cfdc2a999321ff857921e83ccc2c440 504 Gene3D G3DSA:3.40.1080.10 15 238 1.5E-29 T 29-03-2018 CSW12_RS05365 3016ccb2711dbd9588604a07622d9a63 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 1.3E-65 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS05365 3016ccb2711dbd9588604a07622d9a63 269 SUPERFAMILY SSF56784 2 267 7.79E-68 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS05365 3016ccb2711dbd9588604a07622d9a63 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 29-03-2018 CSW12_RS05365 3016ccb2711dbd9588604a07622d9a63 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 3.7E-57 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS05365 3016ccb2711dbd9588604a07622d9a63 269 Gene3D G3DSA:3.40.50.1000 1 268 8.8E-37 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS05365 3016ccb2711dbd9588604a07622d9a63 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 2.1E-28 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 SUPERFAMILY SSF50249 3 65 1.43E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 SUPERFAMILY SSF53335 74 455 9.42E-90 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 Pfam PF01938 TRAM domain 12 64 2.8E-11 T 29-03-2018 IPR002792 TRAM domain CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 383 456 8.1E-13 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 22 450 3.9E-188 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 Gene3D G3DSA:2.40.50.140 1 80 8.2E-24 T 29-03-2018 CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 Gene3D G3DSA:3.40.50.150 81 456 3.7E-62 T 29-03-2018 CSW12_RS00490 5f99d4b6235042045986fe0d23bc8e9e 458 Pfam PF02475 Met-10+ like-protein 211 360 4.2E-9 T 29-03-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 Gene3D G3DSA:2.60.40.10 679 792 1.7E-14 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 642 2.7E-171 T 29-03-2018 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 Pfam PF00041 Fibronectin type III domain 678 752 2.4E-10 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 Gene3D G3DSA:1.10.3810.10 76 277 6.9E-80 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 SMART SM00060 677 751 7.2E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 SUPERFAMILY SSF53955 73 285 5.34E-74 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 Pfam PF00912 Transglycosylase 84 260 2.0E-65 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 615 1.2E-38 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 Gene3D G3DSA:3.40.710.10 281 678 1.5E-95 T 29-03-2018 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 SUPERFAMILY SSF49265 678 759 7.96E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 SUPERFAMILY SSF56601 244 264 2.5E-100 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS19845 586d4eca24a602a0393c9ad58d1b862c 897 SUPERFAMILY SSF56601 295 659 2.5E-100 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS26915 f3910b576a09dc32f0d43ee5e5bb3de5 214 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 55 162 6.7E-10 T 29-03-2018 CSW12_RS02215 6ce28ce29cfa86dd8e1de7dff3c8c689 409 Gene3D G3DSA:1.10.150.20 185 290 2.3E-4 T 29-03-2018 CSW12_RS02215 6ce28ce29cfa86dd8e1de7dff3c8c689 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 280 365 9.2E-25 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS02215 6ce28ce29cfa86dd8e1de7dff3c8c689 409 Pfam PF01548 Transposase 5 165 9.6E-36 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS02215 6ce28ce29cfa86dd8e1de7dff3c8c689 409 Gene3D G3DSA:1.10.150.20 291 373 0.0049 T 29-03-2018 CSW12_RS26270 2ee1e55765aaa5fad2f35a6d200b58fd 172 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 3.4E-26 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26270 2ee1e55765aaa5fad2f35a6d200b58fd 172 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 20 161 7.4E-73 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26270 2ee1e55765aaa5fad2f35a6d200b58fd 172 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 10 160 43.172 T 29-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26270 2ee1e55765aaa5fad2f35a6d200b58fd 172 SUPERFAMILY SSF56770 18 163 5.1E-67 T 29-03-2018 CSW12_RS26270 2ee1e55765aaa5fad2f35a6d200b58fd 172 Gene3D G3DSA:3.40.50.700 19 172 1.5E-48 T 29-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SMART SM00448 776 890 2.7E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SUPERFAMILY SSF47384 481 564 2.35E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 610 731 7.5E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Gene3D G3DSA:3.30.565.10 569 741 8.6E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Pfam PF05227 CHASE3 domain 46 172 1.6E-19 T 29-03-2018 IPR007891 CHASE3 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Gene3D G3DSA:1.10.287.130 486 559 5.5E-18 T 29-03-2018 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Pfam PF00072 Response regulator receiver domain 778 888 5.7E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SUPERFAMILY SSF55874 552 734 1.7E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SUPERFAMILY SSF52172 773 893 1.18E-36 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SMART SM00388 495 563 4.7E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SUPERFAMILY SSF55781 255 439 3.18E-22 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 563 9.5E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 694 712 6.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 718 731 6.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 659 673 6.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 PRINTS PR00344 Bacterial sensor protein C-terminal signature 677 687 6.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Gene3D G3DSA:3.40.50.2300 773 896 3.1E-37 T 29-03-2018 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 SMART SM00387 610 734 9.2E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Pfam PF13185 GAF domain 275 410 9.7E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS04320 09e25e450e45fac3c3303d7871831c37 896 Gene3D G3DSA:3.30.450.40 236 485 7.1E-15 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 SUPERFAMILY SSF89550 2 254 1.08E-16 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Gene3D G3DSA:3.20.20.140 1 246 1.7E-35 T 29-03-2018 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Pfam PF14579 Helix-hairpin-helix motif 778 865 2.9E-18 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 283 705 1.9E-173 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 SMART SM00481 4 71 7.0E-22 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Pfam PF01336 OB-fold nucleic acid binding domain 956 1021 1.2E-7 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Gene3D G3DSA:2.40.50.140 928 1022 7.8E-10 T 29-03-2018 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Gene3D G3DSA:1.10.150.280 761 861 2.8E-4 T 29-03-2018 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 983 0.0 T 29-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22650 28961e14638a80e90016b73ddd86605b 1108 Pfam PF02811 PHP domain 5 164 1.1E-36 T 29-03-2018 IPR004013 PHP domain GO:0003824 CSW12_RS22140 d40795e01e55ee971bafd3444a17b571 303 SUPERFAMILY SSF52540 12 235 9.48E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22140 d40795e01e55ee971bafd3444a17b571 303 Gene3D G3DSA:3.40.50.300 9 291 9.0E-60 T 29-03-2018 CSW12_RS22140 d40795e01e55ee971bafd3444a17b571 303 SMART SM00382 36 214 4.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS22140 d40795e01e55ee971bafd3444a17b571 303 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS22140 d40795e01e55ee971bafd3444a17b571 303 Pfam PF13732 Domain of unknown function (DUF4162) 220 300 1.8E-14 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CSW12_RS22140 d40795e01e55ee971bafd3444a17b571 303 Pfam PF00005 ABC transporter 28 166 4.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 Gene3D G3DSA:1.10.287.990 21 91 3.4E-28 T 29-03-2018 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 197 1.7E-37 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 PIRSF PIRSF000349 1 208 4.7E-77 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 3.6E-29 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 3.9E-23 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 SUPERFAMILY SSF46609 3 92 3.01E-35 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS27010 633e673a95191210ee730190e9a554e1 208 SUPERFAMILY SSF54719 94 204 3.4E-42 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS16830 5a46e4c51dddfe0bc324d3b26e5b78ed 61 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 60 18.949 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CSW12_RS16830 5a46e4c51dddfe0bc324d3b26e5b78ed 61 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 49 7.1E-20 T 29-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CSW12_RS16830 5a46e4c51dddfe0bc324d3b26e5b78ed 61 Pfam PF02416 mttA/Hcf106 family 5 56 5.5E-22 T 29-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CSW12_RS16830 5a46e4c51dddfe0bc324d3b26e5b78ed 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.2E-6 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CSW12_RS16830 5a46e4c51dddfe0bc324d3b26e5b78ed 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.2E-6 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CSW12_RS16830 5a46e4c51dddfe0bc324d3b26e5b78ed 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.2E-6 T 29-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 171 252 5.7E-30 T 29-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 SUPERFAMILY SSF55804 1 148 6.8E-43 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 SUPERFAMILY SSF52794 169 269 3.84E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 29-03-2018 IPR002178 PTS EIIA type-2 domain CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 Gene3D G3DSA:3.40.930.10 1 161 1.8E-49 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 Gene3D G3DSA:3.40.50.2300 168 264 6.6E-38 T 29-03-2018 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 284 614 1.6E-121 T 29-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 171 260 2.3E-17 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 148 3.8E-38 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CSW12_RS09210 b91db38f9fdb7715aac88562572a1e2f 618 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 3.1E-40 T 29-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CSW12_RS07960 c8929f88d22501678dcd2089f5ecd5ae 75 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 17 72 1.0E-10 T 29-03-2018 IPR035211 Protein of unknown function DUF5325 CSW12_RS07960 c8929f88d22501678dcd2089f5ecd5ae 75 Pfam PF17259 Family of unknown function (DUF5325) 17 73 1.6E-19 T 29-03-2018 IPR035211 Protein of unknown function DUF5325 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 SMART SM00342 28 112 1.1E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 SUPERFAMILY SSF46689 12 62 1.79E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 SUPERFAMILY SSF55136 135 294 1.71E-34 T 29-03-2018 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 Pfam PF14526 Integron-associated effector binding protein 139 293 1.3E-30 T 29-03-2018 IPR029441 Integron-associated effector binding protein CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 SMART SM00871 136 294 5.5E-34 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 Gene3D G3DSA:1.10.10.60 62 120 2.7E-14 T 29-03-2018 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 Gene3D G3DSA:3.20.80.10 134 295 7.2E-32 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 SUPERFAMILY SSF46689 65 115 9.86E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 65 108 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 Gene3D G3DSA:1.10.10.60 2 61 1.2E-14 T 29-03-2018 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 Pfam PF12833 Helix-turn-helix domain 34 113 1.3E-19 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 81 96 2.3E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS12485 8818e89ab6b658d4227bded134efe4a5 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 96 112 2.3E-8 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS10195 45d8e0aed6ecc954a7cbf2350896b368 422 Gene3D G3DSA:3.20.20.80 20 417 4.2E-36 T 29-03-2018 CSW12_RS10195 45d8e0aed6ecc954a7cbf2350896b368 422 SUPERFAMILY SSF51445 315 403 8.38E-51 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS10195 45d8e0aed6ecc954a7cbf2350896b368 422 SUPERFAMILY SSF51445 47 288 8.38E-51 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS10195 45d8e0aed6ecc954a7cbf2350896b368 422 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 64 377 2.0E-23 T 29-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CSW12_RS10195 45d8e0aed6ecc954a7cbf2350896b368 422 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 191 200 - T 29-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 Pfam PF00072 Response regulator receiver domain 6 111 1.0E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 Gene3D G3DSA:1.10.10.10 121 225 4.8E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 SMART SM00448 4 114 2.0E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 SMART SM00862 147 222 3.4E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 SUPERFAMILY SSF52172 1 169 2.72E-39 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 Gene3D G3DSA:3.40.50.2300 1 120 4.4E-34 T 29-03-2018 CSW12_RS11625 3a2488fa20a9328b0c53a1178274dfb5 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 1.3E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS16990 066d6a79d581d054ad1c871502fad4c8 531 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 6 94 6.7E-22 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS16990 066d6a79d581d054ad1c871502fad4c8 531 SUPERFAMILY SSF140453 6 96 4.05E-17 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS16990 066d6a79d581d054ad1c871502fad4c8 531 Pfam PF06013 Proteins of 100 residues with WXG 7 91 1.7E-18 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS16990 066d6a79d581d054ad1c871502fad4c8 531 Pfam PF14449 Pre-toxin TG 112 178 6.8E-17 T 29-03-2018 IPR027797 Pre-toxin TG domain CSW12_RS16990 066d6a79d581d054ad1c871502fad4c8 531 Gene3D G3DSA:1.10.287.850 5 93 2.0E-11 T 29-03-2018 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 TIGRFAM TIGR00400 mgtE: magnesium transporter 17 441 2.1E-109 T 29-03-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Pfam PF01769 Divalent cation transporter 312 433 4.1E-28 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Gene3D G3DSA:3.10.580.10 122 256 5.5E-18 T 29-03-2018 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 SMART SM00116 197 245 2.3E-4 T 29-03-2018 IPR000644 CBS domain CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 SMART SM00116 133 186 23.0 T 29-03-2018 IPR000644 CBS domain CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 SUPERFAMILY SSF161093 269 440 4.45E-50 T 29-03-2018 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Gene3D G3DSA:1.10.357.20 268 442 1.2E-43 T 29-03-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Gene3D G3DSA:1.10.220.30 69 121 0.13 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 SUPERFAMILY SSF158791 17 122 1.22E-12 T 29-03-2018 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Pfam PF00571 CBS domain 127 184 3.1E-4 T 29-03-2018 IPR000644 CBS domain CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Pfam PF00571 CBS domain 192 244 3.5E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 SMART SM00924 23 126 2.0E-9 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 SUPERFAMILY SSF54631 125 265 7.71E-28 T 29-03-2018 CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Gene3D G3DSA:1.10.220.30 1 68 0.0048 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS15120 f0a1ef181d5ef6ab7f794a561d277c6d 442 Pfam PF03448 MgtE intracellular N domain 24 123 7.8E-11 T 29-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 SUPERFAMILY SSF88713 466 679 7.66E-56 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 SMART SM00636 108 400 4.7E-12 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 SUPERFAMILY SSF53448 746 1016 7.03E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 Pfam PF01522 Polysaccharide deacetylase 479 586 4.1E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 Pfam PF13641 Glycosyltransferase like family 2 754 976 4.1E-36 T 29-03-2018 CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 SUPERFAMILY SSF51445 108 316 1.15E-38 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 SUPERFAMILY SSF51445 372 410 1.15E-38 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 Gene3D G3DSA:3.20.20.80 52 426 1.0E-46 T 29-03-2018 CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 Gene3D G3DSA:3.90.550.10 734 999 1.6E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 Gene3D G3DSA:3.20.20.370 446 687 7.4E-52 T 29-03-2018 CSW12_RS10800 b25bad770eb66afd02def860cc7f170d 1115 Pfam PF00704 Glycosyl hydrolases family 18 129 399 6.3E-23 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.073 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 3.5E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 3.5E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 3.5E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 3.5E-23 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 Gene3D G3DSA:3.90.230.10 1 248 3.2E-86 T 29-03-2018 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 SUPERFAMILY SSF55920 1 246 4.97E-93 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 Pfam PF00557 Metallopeptidase family M24 12 239 8.4E-58 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS28095 0c0b59c0a98903b50aa889eaba7c5bfb 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.8E-103 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS09145 4bf7ef072cf129889dd7f1ba46991678 159 Pfam PF13673 Acetyltransferase (GNAT) domain 31 153 1.3E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS09145 4bf7ef072cf129889dd7f1ba46991678 159 SUPERFAMILY SSF55729 4 155 3.31E-32 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS09145 4bf7ef072cf129889dd7f1ba46991678 159 Gene3D G3DSA:3.40.630.30 2 157 1.5E-25 T 29-03-2018 CSW12_RS12765 4d0f466af3cc9263fb836e732b29afde 404 SUPERFAMILY SSF103473 6 390 4.45E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12765 4d0f466af3cc9263fb836e732b29afde 404 Gene3D G3DSA:1.20.1250.20 1 193 3.4E-21 T 29-03-2018 CSW12_RS12765 4d0f466af3cc9263fb836e732b29afde 404 Pfam PF07690 Major Facilitator Superfamily 31 348 1.2E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS12765 4d0f466af3cc9263fb836e732b29afde 404 Gene3D G3DSA:1.20.1250.20 206 403 5.1E-22 T 29-03-2018 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 Gene3D G3DSA:3.10.310.10 131 271 5.0E-49 T 29-03-2018 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 37.845 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 2.0E-96 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 SUPERFAMILY SSF54506 3 284 4.86E-52 T 29-03-2018 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 29-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 Gene3D G3DSA:3.10.310.10 1 130 5.6E-46 T 29-03-2018 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 Pfam PF01678 Diaminopimelate epimerase 161 276 8.2E-35 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CSW12_RS24485 2e91dab750416a749771a5c146e379bd 288 Pfam PF01678 Diaminopimelate epimerase 6 130 7.3E-32 T 29-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 SUPERFAMILY SSF103473 8 393 4.19E-76 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 Gene3D G3DSA:1.20.1250.20 209 397 6.1E-24 T 29-03-2018 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 PRINTS PR01035 Tetracycline resistance protein signature 164 184 1.1E-23 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.1E-23 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 PRINTS PR01035 Tetracycline resistance protein signature 21 37 1.1E-23 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 PRINTS PR01035 Tetracycline resistance protein signature 78 102 1.1E-23 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.1E-23 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 Pfam PF07690 Major Facilitator Superfamily 16 357 1.3E-56 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS03525 49fd26064024ad0360ec0140fce30899 400 Gene3D G3DSA:1.20.1250.20 6 203 1.4E-44 T 29-03-2018 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 PIRSF PIRSF001123 2 356 5.6E-153 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 SUPERFAMILY SSF101821 71 180 4.12E-31 T 29-03-2018 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 2.8E-112 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 Gene3D G3DSA:3.40.630.10 167 356 1.5E-43 T 29-03-2018 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 SUPERFAMILY SSF53187 4 81 9.05E-71 T 29-03-2018 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 SUPERFAMILY SSF53187 172 351 9.05E-71 T 29-03-2018 CSW12_RS23160 124500157b1b893640d537e5583438d7 357 Gene3D G3DSA:2.40.30.40 70 161 7.3E-31 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CSW12_RS16730 4950e81544bbe40fb49ae5139b8ce579 186 SMART SM00530 7 62 1.7E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS16730 4950e81544bbe40fb49ae5139b8ce579 186 SUPERFAMILY SSF47413 2 69 8.16E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS16730 4950e81544bbe40fb49ae5139b8ce579 186 Pfam PF01381 Helix-turn-helix 8 60 2.5E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS16730 4950e81544bbe40fb49ae5139b8ce579 186 Gene3D G3DSA:1.10.260.40 3 180 3.3E-17 T 29-03-2018 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 711 757 4.7E-15 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 509 552 7.5E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 613 657 1.4E-9 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 2.0E-14 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 761 805 1.8E-13 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 597 8.7E-12 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 34 473 2.7E-161 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:3.90.199.10 36 216 8.2E-85 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:3.30.1360.40 238 334 4.7E-40 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 809 25.213 T 29-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 SUPERFAMILY SSF56719 32 488 1.44E-183 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 SUPERFAMILY SSF101904 501 821 3.14E-116 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:2.120.10.90 501 823 1.4E-131 T 29-03-2018 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 Gene3D G3DSA:1.10.268.10 346 488 3.1E-55 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 808 0.0 T 29-03-2018 CSW12_RS27335 8830ce2a3a8fc9b94a85dd944d1e30cb 823 SMART SM00434 13 466 1.6E-294 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 SUPERFAMILY SSF69055 288 379 1.57E-32 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 128 1.4E-41 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 47.499 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 SUPERFAMILY SSF51735 2 146 6.47E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 Gene3D G3DSA:3.40.50.720 1 146 5.2E-47 T 29-03-2018 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 PIRSF PIRSF006205 1 380 1.0E-162 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 142 225 1.7E-42 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 SUPERFAMILY SSF55347 123 260 6.87E-62 T 29-03-2018 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 Gene3D G3DSA:1.10.1740.10 300 380 1.1E-30 T 29-03-2018 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 378 7.4E-172 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS08670 6677fdcce955fe5433c0878f2709c55a 380 Pfam PF13288 DXP reductoisomerase C-terminal domain 257 374 7.0E-45 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 6.8E-25 T 29-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 Gene3D G3DSA:1.10.60.10 75 136 5.7E-22 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 123 7.7E-18 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 48.072 T 29-03-2018 IPR022897 Transcription regulator MntR CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 SMART SM00529 24 123 7.1E-44 T 29-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 SUPERFAMILY SSF47979 63 130 3.06E-18 T 29-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 Gene3D G3DSA:1.10.10.10 2 72 1.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20610 b93b1f030c8856fcb42efc9a56f16a37 142 SUPERFAMILY SSF46785 3 62 3.97E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 486 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.3E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Pfam PF17203 Single cache domain 3 38 173 2.6E-22 T 29-03-2018 IPR033463 Single cache domain 3 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 525 7.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Gene3D G3DSA:3.30.450.20 206 320 2.0E-12 T 29-03-2018 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 SMART SM00387 420 527 4.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Pfam PF00989 PAS fold 214 313 4.4E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Gene3D G3DSA:3.30.450.20 33 174 1.3E-24 T 29-03-2018 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Gene3D G3DSA:1.10.287.130 321 375 3.6E-17 T 29-03-2018 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 327 372 3.8E-11 T 29-03-2018 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 Gene3D G3DSA:3.30.565.10 378 527 8.7E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 SUPERFAMILY SSF55890 324 394 7.19E-14 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 SUPERFAMILY SSF103190 40 171 9.81E-40 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 SUPERFAMILY SSF55874 392 524 2.62E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01595 f83021d64b1d480fa6a24628e7031c87 532 SUPERFAMILY SSF55785 213 312 6.75E-8 T 29-03-2018 IPR000014 PAS domain CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 SUPERFAMILY SSF109755 3 215 5.97E-63 T 29-03-2018 CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 Gene3D G3DSA:1.20.58.220 1 113 4.2E-26 T 29-03-2018 CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 213 1.3E-69 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 PIRSF PIRSF003107 1 218 4.1E-62 T 29-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 Pfam PF01895 PhoU domain 18 104 1.9E-20 T 29-03-2018 IPR026022 PhoU domain CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 Pfam PF01895 PhoU domain 120 204 4.5E-19 T 29-03-2018 IPR026022 PhoU domain CSW12_RS20950 bfab2b0bac86c7215a95263eb42591d9 218 Gene3D G3DSA:1.20.58.220 117 218 1.3E-24 T 29-03-2018 CSW12_RS11690 c790bcaee27897ba2de4f6fe1f936c45 331 SUPERFAMILY SSF53686 4 325 2.47E-89 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS11690 c790bcaee27897ba2de4f6fe1f936c45 331 PIRSF PIRSF006278 1 331 1.2E-91 T 29-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CSW12_RS11690 c790bcaee27897ba2de4f6fe1f936c45 331 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 14 326 8.0E-98 T 29-03-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 CSW12_RS11690 c790bcaee27897ba2de4f6fe1f936c45 331 Gene3D G3DSA:3.40.50.1100 144 327 5.9E-30 T 29-03-2018 CSW12_RS11690 c790bcaee27897ba2de4f6fe1f936c45 331 Gene3D G3DSA:3.40.50.1100 48 143 6.6E-31 T 29-03-2018 CSW12_RS11690 c790bcaee27897ba2de4f6fe1f936c45 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 318 1.7E-55 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS03295 caba304aa92c675552fec4383c4e5a2e 106 Gene3D G3DSA:1.20.58.80 3 99 9.6E-36 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS03295 caba304aa92c675552fec4383c4e5a2e 106 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 7 98 1.5E-35 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS03295 caba304aa92c675552fec4383c4e5a2e 106 SUPERFAMILY SSF46973 5 99 1.57E-34 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS03295 caba304aa92c675552fec4383c4e5a2e 106 PIRSF PIRSF000699 1 105 2.1E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 8.8E-49 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 Gene3D G3DSA:3.40.50.970 3 188 1.8E-47 T 29-03-2018 CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 4.5E-40 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 SUPERFAMILY SSF52467 185 350 6.55E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 Gene3D G3DSA:3.40.50.1220 189 344 2.3E-40 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 SUPERFAMILY SSF52518 358 553 3.4E-63 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 Gene3D G3DSA:3.40.50.970 345 544 3.4E-46 T 29-03-2018 CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 SUPERFAMILY SSF52518 3 170 1.07E-48 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS16070 117640dfba03b6e561a92cc4b4fca180 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 319 1.6E-35 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CSW12_RS25495 f33d213ec5aafcb89a28862150126d8d 170 Gene3D G3DSA:2.160.10.10 26 159 8.6E-27 T 29-03-2018 CSW12_RS25495 f33d213ec5aafcb89a28862150126d8d 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 107 140 3.2E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS25495 f33d213ec5aafcb89a28862150126d8d 170 SUPERFAMILY SSF51161 11 158 3.6E-32 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS16295 d0aec7be59d8008957b71ff7c92028f8 96 PIRSF PIRSF034852 1 96 1.3E-35 T 29-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CSW12_RS16295 d0aec7be59d8008957b71ff7c92028f8 96 SUPERFAMILY SSF89360 1 94 7.65E-9 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS16295 d0aec7be59d8008957b71ff7c92028f8 96 Gene3D G3DSA:2.60.300.12 1 96 4.6E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS16295 d0aec7be59d8008957b71ff7c92028f8 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 92 4.3E-6 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 SUPERFAMILY SSF56784 14 147 4.4E-25 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 27 137 6.0E-24 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 36 135 8.8E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 2 163 7.0E-58 T 29-03-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 58 129 1.2E-5 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 Pfam PF13242 HAD-hyrolase-like 90 135 1.8E-11 T 29-03-2018 CSW12_RS21310 0d078cc2df05d9a1f237b38d5a90952d 170 Gene3D G3DSA:3.40.50.1000 14 159 4.4E-24 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26175 520b79bcabe960fc2a6bd8e94e03d484 132 Gene3D G3DSA:1.10.10.10 36 74 2.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26175 520b79bcabe960fc2a6bd8e94e03d484 132 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 44 123 4.1E-45 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CSW12_RS26175 520b79bcabe960fc2a6bd8e94e03d484 132 Pfam PF12116 Stage III sporulation protein D 44 124 9.4E-41 T 29-03-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID CSW12_RS26175 520b79bcabe960fc2a6bd8e94e03d484 132 Gene3D G3DSA:1.10.260.40 75 124 2.6E-4 T 29-03-2018 CSW12_RS26175 520b79bcabe960fc2a6bd8e94e03d484 132 ProSitePatterns PS00894 DeoR-type HTH domain signature. 50 83 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 Gene3D G3DSA:2.40.50.140 9 100 1.1E-17 T 29-03-2018 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 SUPERFAMILY SSF55681 90 430 9.95E-86 T 29-03-2018 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 425 6.5E-82 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 16 432 4.3E-135 T 29-03-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 5 432 39.907 T 29-03-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 Gene3D G3DSA:3.30.930.10 101 420 2.2E-81 T 29-03-2018 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 SUPERFAMILY SSF50249 12 101 9.26E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 Pfam PF01336 OB-fold nucleic acid binding domain 21 93 7.2E-10 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 5.2E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 199 212 5.2E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 5.2E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17035 8eff9fa360dd7b2a49c76371da81a8d6 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 347 363 5.2E-20 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 SUPERFAMILY SSF46894 138 209 2.75E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 Pfam PF00072 Response regulator receiver domain 6 116 1.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 SUPERFAMILY SSF52172 2 132 1.17E-35 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 Gene3D G3DSA:3.40.50.2300 2 127 2.8E-36 T 29-03-2018 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 2.1E-22 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 Gene3D G3DSA:1.10.10.10 128 210 8.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.2E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 SMART SM00448 3 116 8.4E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS16650 ab0fe928ba3cb304e54bfe483637e253 213 SMART SM00421 148 205 1.9E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 2.8E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.8E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.8E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 2.8E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 2.8E-29 T 29-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Gene3D G3DSA:3.40.50.620 5 128 7.4E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Gene3D G3DSA:1.10.8.70 334 384 2.4E-4 T 29-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 SUPERFAMILY SSF48163 298 483 5.49E-49 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 2.5E-123 T 29-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Gene3D G3DSA:1.10.10.350 386 485 2.1E-28 T 29-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Gene3D G3DSA:1.10.1160.10 247 333 2.1E-31 T 29-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 482 7.8E-190 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 SUPERFAMILY SSF52374 4 316 1.02E-113 T 29-03-2018 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 484 33.79 T 29-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CSW12_RS27865 3ddea91093dd0caa4fe99180a3150ecc 485 Gene3D G3DSA:3.40.50.620 129 246 3.9E-28 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS03115 d41838f0276b94d9136e412ed581eaea 360 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 359 6.7E-91 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS03115 d41838f0276b94d9136e412ed581eaea 360 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 194 357 1.1E-22 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS02355 65080728e8daaff2aca4977aa1300442 366 Gene3D G3DSA:1.10.150.130 52 164 1.2E-19 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS02355 65080728e8daaff2aca4977aa1300442 366 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 57 113 1.3E-13 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CSW12_RS02355 65080728e8daaff2aca4977aa1300442 366 Pfam PF00589 Phage integrase family 165 337 1.3E-26 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS02355 65080728e8daaff2aca4977aa1300442 366 Gene3D G3DSA:1.10.443.10 165 354 6.8E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS02355 65080728e8daaff2aca4977aa1300442 366 Pfam PF14657 Arm DNA-binding domain 11 53 9.3E-12 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain CSW12_RS02355 65080728e8daaff2aca4977aa1300442 366 SUPERFAMILY SSF56349 56 344 2.5E-65 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 14 232 36.35 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 PIRSF PIRSF005917 3 291 4.4E-104 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 92 103 - T 29-03-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 213 3.5E-28 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 287 5.9E-81 T 29-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 SUPERFAMILY SSF53790 12 230 3.14E-82 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 Gene3D G3DSA:3.30.950.10 123 235 3.7E-42 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS27525 ac960d660881eda7af52f36c6c581b42 291 Gene3D G3DSA:3.40.1010.10 12 122 2.6E-42 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 Gene3D G3DSA:3.40.350.10 1 128 1.3E-26 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 Gene3D G3DSA:3.90.230.10 129 365 3.3E-81 T 29-03-2018 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 4.1E-9 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 4.1E-9 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 4.1E-9 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 SUPERFAMILY SSF53092 1 136 4.71E-37 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 Pfam PF00557 Metallopeptidase family M24 147 348 1.8E-65 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 138 4.2E-29 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CSW12_RS22695 e609b87f46c6a0849249b492529f8bed 365 SUPERFAMILY SSF55920 137 363 7.85E-82 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS21295 18c0d306628ac3a0c17e89ce8603c9ed 97 Gene3D G3DSA:3.30.110.60 1 97 4.0E-29 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CSW12_RS21295 18c0d306628ac3a0c17e89ce8603c9ed 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.3E-22 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CSW12_RS21295 18c0d306628ac3a0c17e89ce8603c9ed 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 97 2.0E-44 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CSW12_RS21295 18c0d306628ac3a0c17e89ce8603c9ed 97 SUPERFAMILY SSF75471 1 95 1.2E-31 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CSW12_RS21295 18c0d306628ac3a0c17e89ce8603c9ed 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 97 3.7E-41 T 29-03-2018 IPR017924 RNA-binding protein YhbY GO:0003723 CSW12_RS21295 18c0d306628ac3a0c17e89ce8603c9ed 97 SMART SM01103 2 85 1.5E-41 T 29-03-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 SUPERFAMILY SSF47729 1 90 4.27E-36 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.0E-38 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 Gene3D G3DSA:4.10.520.10 1 90 8.1E-40 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.7E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.7E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.7E-22 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS20050 9ef78c0a5fb71fd4c0c6bf512476a659 90 SMART SM00411 1 90 8.2E-53 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 SUPERFAMILY SSF101904 498 803 7.19E-91 T 29-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 655 696 1.2E-6 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 607 650 2.9E-6 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 503 517 1.5 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 753 5.0E-5 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 598 8.1E-5 T 29-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:3.30.1360.40 234 330 5.2E-34 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 469 3.3E-150 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:3.90.199.10 32 213 2.0E-74 T 29-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:1.10.268.10 342 484 3.7E-47 T 29-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Gene3D G3DSA:2.120.10.90 498 807 1.3E-82 T 29-03-2018 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 6 744 0.0 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 SMART SM00434 9 462 2.8E-259 T 29-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 5 803 34.026 T 29-03-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09765 8bff9b4fc9bffd72f8fde3eeee6857cb 807 SUPERFAMILY SSF56719 29 483 1.24E-167 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CSW12_RS21820 3413efb4b2b6acb6685cacbb3366ac72 258 Pfam PF00005 ABC transporter 24 172 2.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS21820 3413efb4b2b6acb6685cacbb3366ac72 258 Gene3D G3DSA:3.40.50.300 1 240 1.5E-62 T 29-03-2018 CSW12_RS21820 3413efb4b2b6acb6685cacbb3366ac72 258 SUPERFAMILY SSF52540 3 225 2.5E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21820 3413efb4b2b6acb6685cacbb3366ac72 258 SMART SM00382 33 221 1.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 Gene3D G3DSA:3.30.1300.10 175 282 5.0E-30 T 29-03-2018 CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 279 3.3E-109 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 73 7.7E-8 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 Gene3D G3DSA:3.40.50.620 1 174 7.5E-75 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 Pfam PF02569 Pantoate-beta-alanine ligase 2 277 4.3E-100 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 SUPERFAMILY SSF52374 1 280 6.14E-104 T 29-03-2018 CSW12_RS19890 581b58925593fd4eb12454df92b9d81e 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 38.444 T 29-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CSW12_RS01970 9e2b94eb5a4a596ded70e188a8e6f01e 483 Gene3D G3DSA:3.30.750.24 383 477 1.2E-10 T 29-03-2018 IPR002645 STAS domain CSW12_RS01970 9e2b94eb5a4a596ded70e188a8e6f01e 483 SUPERFAMILY SSF52091 387 471 5.3E-9 T 29-03-2018 IPR002645 STAS domain CSW12_RS01970 9e2b94eb5a4a596ded70e188a8e6f01e 483 Pfam PF00916 Sulfate permease family 14 139 6.4E-25 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS01970 9e2b94eb5a4a596ded70e188a8e6f01e 483 Pfam PF00916 Sulfate permease family 142 354 5.1E-32 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS26355 9dee88e226f49d03980f1c8ac34b68ff 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 47.969 T 29-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CSW12_RS26355 9dee88e226f49d03980f1c8ac34b68ff 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.3E-92 T 29-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CSW12_RS26355 9dee88e226f49d03980f1c8ac34b68ff 209 Gene3D G3DSA:3.40.50.2020 2 207 2.5E-64 T 29-03-2018 CSW12_RS26355 9dee88e226f49d03980f1c8ac34b68ff 209 SUPERFAMILY SSF53271 4 207 9.96E-73 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS26355 9dee88e226f49d03980f1c8ac34b68ff 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 2.4E-75 T 29-03-2018 CSW12_RS27410 d3af78fe33c10840b7d5660b558a31d1 211 Gene3D G3DSA:3.40.50.300 2 210 4.4E-37 T 29-03-2018 CSW12_RS27410 d3af78fe33c10840b7d5660b558a31d1 211 Pfam PF01712 Deoxynucleoside kinase 7 204 4.4E-45 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain CSW12_RS27410 d3af78fe33c10840b7d5660b558a31d1 211 PIRSF PIRSF000705 2 210 4.2E-56 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CSW12_RS27410 d3af78fe33c10840b7d5660b558a31d1 211 SUPERFAMILY SSF52540 5 205 5.14E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 234 784 3.3E-163 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Gene3D G3DSA:3.40.1110.10 500 599 5.3E-20 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00941 Cadmium-transporting ATPase signature 349 365 1.2E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00941 Cadmium-transporting ATPase signature 268 288 1.2E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00941 Cadmium-transporting ATPase signature 368 382 1.2E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00941 Cadmium-transporting ATPase signature 88 97 1.2E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00941 Cadmium-transporting ATPase signature 99 120 1.2E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00941 Cadmium-transporting ATPase signature 196 213 1.2E-16 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF81653 286 383 6.15E-25 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 485 499 4.1E-21 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 4.1E-21 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 698 4.1E-21 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 703 715 4.1E-21 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 633 4.1E-21 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 257 759 4.0E-78 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF55008 85 160 6.68E-12 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Pfam PF00122 E1-E2 ATPase 284 464 1.8E-50 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF55008 6 71 7.2E-12 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 234 782 1.9E-176 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Pfam PF00403 Heavy-metal-associated domain 10 71 2.9E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Pfam PF00403 Heavy-metal-associated domain 87 135 3.6E-10 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Gene3D G3DSA:3.30.70.100 6 84 2.3E-11 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF81665 384 479 2.09E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF81665 234 287 2.09E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF81665 729 777 2.09E-13 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Gene3D G3DSA:3.40.50.1000 600 752 3.8E-34 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 ProSitePatterns PS01047 Heavy-metal-associated domain. 12 41 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF56784 483 503 1.65E-60 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 SUPERFAMILY SSF56784 541 780 1.65E-60 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Gene3D G3DSA:3.30.70.100 85 174 6.5E-13 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 487 493 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 ProSitePatterns PS01047 Heavy-metal-associated domain. 90 119 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 693 1.7E-34 T 29-03-2018 CSW12_RS01695 1a939d80bc62e583e81880cf4da18795 788 Gene3D G3DSA:1.20.1110.10 232 499 3.6E-36 T 29-03-2018 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Gene3D G3DSA:1.10.287.1150 70 154 1.4E-8 T 29-03-2018 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 935 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Gene3D G3DSA:3.40.50.970 155 520 3.9E-79 T 29-03-2018 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 791 937 6.6E-37 T 29-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 1 939 23.363 T 29-03-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Pfam PF00676 Dehydrogenase E1 component 223 520 1.5E-62 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 PIRSF PIRSF000157 1 939 0.0 T 29-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Gene3D G3DSA:3.40.50.970 586 802 8.2E-49 T 29-03-2018 CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 SUPERFAMILY SSF52518 572 791 5.99E-43 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 Pfam PF02779 Transketolase, pyrimidine binding domain 589 787 1.1E-54 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 SMART SM00861 590 786 1.2E-42 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS05840 87bb21a711faad731151b0bc2e0fd8af 955 SUPERFAMILY SSF52518 152 522 1.7E-71 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS11445 a06e71497bf81828f0c9ed5b9fcca9b6 181 Gene3D G3DSA:1.10.10.10 4 165 2.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11445 a06e71497bf81828f0c9ed5b9fcca9b6 181 SUPERFAMILY SSF46785 6 149 9.31E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11445 a06e71497bf81828f0c9ed5b9fcca9b6 181 Pfam PF12840 Helix-turn-helix domain 6 64 5.8E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11445 a06e71497bf81828f0c9ed5b9fcca9b6 181 SMART SM00418 3 87 0.0051 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 Gene3D G3DSA:2.20.150.10 9 42 1.8E-15 T 29-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 Gene3D G3DSA:3.40.1190.20 43 303 1.9E-42 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 1.4E-114 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 Pfam PF00294 pfkB family carbohydrate kinase 11 280 1.6E-53 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 3.8E-112 T 29-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 PIRSF PIRSF000535 1 303 2.3E-93 T 29-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CSW12_RS09205 c357f9c50d27916725f6fd3457b40334 303 SUPERFAMILY SSF53613 1 282 1.12E-70 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 Gene3D G3DSA:3.40.50.1390 1 123 7.1E-27 T 29-03-2018 CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 Gene3D G3DSA:1.20.5.40 124 151 6.0E-13 T 29-03-2018 CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 SUPERFAMILY SSF53041 4 153 1.7E-34 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 SMART SM00857 5 153 2.8E-37 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 Pfam PF00239 Resolvase, N terminal domain 6 153 3.2E-30 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 ProSitePatterns PS00398 Site-specific recombinases signature 2. 60 72 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30610 3ca3098cae29e6331aa416d0d5027032 213 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 177 1.2E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 SUPERFAMILY SSF88946 4 98 1.46E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 Pfam PF04542 Sigma-70 region 2 30 91 2.6E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 Gene3D G3DSA:1.10.10.10 108 187 1.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 Pfam PF08281 Sigma-70, region 4 122 174 3.0E-16 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 SUPERFAMILY SSF88659 113 176 1.87E-16 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS17335 fc863783b13bad72f43f27ebf1e46c3a 192 Gene3D G3DSA:1.10.1740.10 1 107 9.7E-20 T 29-03-2018 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 SUPERFAMILY SSF47644 617 700 6.28E-24 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Gene3D G3DSA:1.10.1240.10 614 692 9.6E-28 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Pfam PF02607 B12 binding domain 621 694 2.9E-22 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 SUPERFAMILY SSF82282 2 373 1.27E-111 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 PIRSF PIRSF000381 1 1132 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 SMART SM01018 618 701 3.4E-38 T 29-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 SUPERFAMILY SSF52242 702 846 4.97E-39 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 SUPERFAMILY SSF51717 331 597 7.72E-80 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Gene3D G3DSA:3.40.50.280 693 850 3.9E-48 T 29-03-2018 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Pfam PF00809 Pterin binding enzyme 334 567 4.3E-40 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Pfam PF02574 Homocysteine S-methyltransferase 13 300 1.5E-76 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Gene3D G3DSA:3.20.20.330 1 313 7.6E-103 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Gene3D G3DSA:3.10.196.10 911 1132 3.4E-57 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 SUPERFAMILY SSF56507 866 1131 2.62E-83 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Pfam PF02310 B12 binding domain 707 796 3.7E-21 T 29-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Gene3D G3DSA:3.20.20.20 319 613 2.4E-54 T 29-03-2018 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 905 1131 9.8E-52 T 29-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS20880 a0fe06b1628b3d9269f0630c8b230d99 1132 TIGRFAM TIGR02082 metH: methionine synthase 8 1131 0.0 T 29-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS30340 26cde02ecd0add2e385654d58b53607c 313 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 245 2.3E-60 T 29-03-2018 CSW12_RS30340 26cde02ecd0add2e385654d58b53607c 313 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 262 2.9E-58 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS30340 26cde02ecd0add2e385654d58b53607c 313 Gene3D G3DSA:1.10.10.60 243 313 3.3E-11 T 29-03-2018 CSW12_RS13665 343899f5930f9a3c25bdf448f652fac2 134 SUPERFAMILY SSF55729 6 126 2.23E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13665 343899f5930f9a3c25bdf448f652fac2 134 Pfam PF00583 Acetyltransferase (GNAT) family 30 113 2.1E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13665 343899f5930f9a3c25bdf448f652fac2 134 Gene3D G3DSA:3.40.630.30 3 134 1.7E-16 T 29-03-2018 CSW12_RS10740 adbd3dc144ba6a2aaacdafb1587bdcf4 113 SUPERFAMILY SSF158560 1 108 1.7E-35 T 29-03-2018 CSW12_RS10740 adbd3dc144ba6a2aaacdafb1587bdcf4 113 PIRSF PIRSF029876 3 111 7.7E-46 T 29-03-2018 IPR008316 Uncharacterised conserved protein UCP029876 CSW12_RS10740 adbd3dc144ba6a2aaacdafb1587bdcf4 113 Gene3D G3DSA:1.10.1900.10 20 103 7.5E-33 T 29-03-2018 CSW12_RS10740 adbd3dc144ba6a2aaacdafb1587bdcf4 113 Pfam PF06304 Protein of unknown function (DUF1048) 7 106 2.5E-42 T 29-03-2018 IPR008316 Uncharacterised conserved protein UCP029876 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 7 469 3.5E-200 T 29-03-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00230+2.7.1.20|KEGG: 00500+2.7.1.201|MetaCyc: PWY-6619 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 SUPERFAMILY SSF55604 8 83 3.66E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 Gene3D G3DSA:3.30.1360.60 4 79 3.6E-24 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 Pfam PF00367 phosphotransferase system, EIIB 11 43 8.6E-15 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 Pfam PF02378 Phosphotransferase system, EIIC 112 412 2.2E-43 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS01860 90f7163629541e977c700577114b1d84 475 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 30 112 1.6E-17 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS01295 4cc427847ec9a5963d738893169a34b4 118 Pfam PF11023 Zinc-ribbon containing domain 4 114 4.3E-59 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CSW12_RS01295 4cc427847ec9a5963d738893169a34b4 118 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 4 115 9.0E-62 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CSW12_RS01295 4cc427847ec9a5963d738893169a34b4 118 Hamap MF_01502 UPF0295 protein . 2 116 37.621 T 29-03-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 SMART SM00411 1 90 4.5E-47 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 SUPERFAMILY SSF47729 1 90 6.04E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.2E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.2E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.2E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 Gene3D G3DSA:4.10.520.10 1 90 6.3E-36 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.6E-35 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS09150 32cff7ba3b3ff402f40f3c0d7d88fa0b 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 Pfam PF12848 ABC transporter 230 315 6.8E-21 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 SMART SM00382 28 236 1.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 SMART SM00382 349 514 1.1E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 SUPERFAMILY SSF52540 316 508 7.05E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 Gene3D G3DSA:3.40.50.300 292 514 7.0E-39 T 29-03-2018 CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 SUPERFAMILY SSF52540 4 232 1.62E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 Pfam PF00005 ABC transporter 20 191 1.6E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 Pfam PF00005 ABC transporter 342 468 5.2E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26930 7f265dca9d7b3ce6abf8aee2c8de5966 517 Gene3D G3DSA:3.40.50.300 1 291 2.4E-50 T 29-03-2018 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 Gene3D G3DSA:3.40.50.970 195 503 7.8E-63 T 29-03-2018 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 449 1.4E-61 T 29-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 2.1E-40 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 SUPERFAMILY SSF53323 1 221 7.06E-46 T 29-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 574 1.4E-212 T 29-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 476 570 5.8E-12 T 29-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 SUPERFAMILY SSF52518 196 458 3.66E-73 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 Gene3D G3DSA:3.40.920.10 2 181 1.6E-41 T 29-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CSW12_RS08910 ce896b05dda22edbe5908d27cccfc494 585 SUPERFAMILY SSF52922 468 576 4.19E-24 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS03260 11d39fa7cf81c2e698b2aae370c3e2e1 411 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 112 268 7.9E-42 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS03260 11d39fa7cf81c2e698b2aae370c3e2e1 411 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 112 268 8.3E-36 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 PIRSF PIRSF000303 1 160 1.4E-68 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 SUPERFAMILY SSF52833 1 158 5.99E-64 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 Pfam PF00255 Glutathione peroxidase 3 109 6.3E-44 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 29-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.1E-21 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.1E-21 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.1E-21 T 29-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 Gene3D G3DSA:3.40.30.10 1 160 7.1E-52 T 29-03-2018 CSW12_RS17310 2aca70a57d40829106af8b56858b4ade 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 29-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 SMART SM00354 2 72 1.7E-29 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 Gene3D G3DSA:1.10.260.40 3 55 3.6E-22 T 29-03-2018 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 SUPERFAMILY SSF53822 61 337 9.62E-75 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 Pfam PF13377 Periplasmic binding protein-like domain 175 336 1.6E-31 T 29-03-2018 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 Gene3D G3DSA:3.40.50.2300 182 341 5.8E-42 T 29-03-2018 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 Gene3D G3DSA:3.40.50.2300 56 181 2.6E-32 T 29-03-2018 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.6E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07680 5ad63c8941c88586f1109765a5c7d1a4 343 SUPERFAMILY SSF47413 2 60 1.34E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS25980 095a4d0cbc81555fafb477609d6cb727 163 Pfam PF12773 Double zinc ribbon 106 157 4.4E-7 T 29-03-2018 IPR025874 Double zinc ribbon CSW12_RS24685 f9f695e54365395274968bba3c4428c1 100 Gene3D G3DSA:3.30.1980.10 1 99 7.7E-38 T 29-03-2018 CSW12_RS24685 f9f695e54365395274968bba3c4428c1 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 3.8E-23 T 29-03-2018 IPR014931 Protein of unknown function DUF1805 CSW12_RS24685 f9f695e54365395274968bba3c4428c1 100 SUPERFAMILY SSF102891 1 99 1.83E-34 T 29-03-2018 IPR014931 Protein of unknown function DUF1805 CSW12_RS23265 8a025ee2a1b356477828cb894eeff413 164 Pfam PF02559 CarD-like/TRCF domain 7 115 1.1E-20 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS23265 8a025ee2a1b356477828cb894eeff413 164 Gene3D G3DSA:3.90.1480.10 74 164 7.4E-4 T 29-03-2018 CSW12_RS23265 8a025ee2a1b356477828cb894eeff413 164 SMART SM01058 6 116 5.1E-35 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS23265 8a025ee2a1b356477828cb894eeff413 164 SUPERFAMILY SSF141259 7 70 4.18E-14 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 Gene3D G3DSA:2.120.10.30 3 292 2.0E-41 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 258 3.4E-76 T 29-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 133 155 9.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 196 213 9.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 239 257 9.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 9.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 176 9.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 92 113 9.0E-47 T 29-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CSW12_RS14775 9ffc5ab18e4a1b309e07388f57c663e0 300 SUPERFAMILY SSF63829 10 290 4.58E-65 T 29-03-2018 CSW12_RS12620 d667091135d55bf22b58bee2d2e7e5dc 105 Gene3D G3DSA:1.10.10.10 1 99 5.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12620 d667091135d55bf22b58bee2d2e7e5dc 105 Pfam PF03551 Transcriptional regulator PadR-like family 23 86 1.5E-13 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS12620 d667091135d55bf22b58bee2d2e7e5dc 105 SUPERFAMILY SSF46785 10 100 1.05E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12710 08746b4c28734adaa19e32b34bb011bb 115 SUPERFAMILY SSF54593 6 114 4.65E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12710 08746b4c28734adaa19e32b34bb011bb 115 Gene3D G3DSA:3.10.180.10 1 115 1.4E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS19025 6c9f9424cc15f47dd1641a3f7b9420d6 56 Pfam PF13076 Fur-regulated basic protein A 12 46 3.0E-17 T 29-03-2018 IPR025072 Fur-regulated basic protein A CSW12_RS11215 eee1ccb6bcf1978d3dde9d5bd5aac398 151 PRINTS PR00502 NUDIX hydrolase family signature 43 57 2.6E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS11215 eee1ccb6bcf1978d3dde9d5bd5aac398 151 PRINTS PR00502 NUDIX hydrolase family signature 57 72 2.6E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS11215 eee1ccb6bcf1978d3dde9d5bd5aac398 151 Gene3D G3DSA:3.90.79.10 1 150 5.4E-24 T 29-03-2018 CSW12_RS11215 eee1ccb6bcf1978d3dde9d5bd5aac398 151 Pfam PF00293 NUDIX domain 23 145 6.0E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS11215 eee1ccb6bcf1978d3dde9d5bd5aac398 151 SUPERFAMILY SSF55811 1 147 9.88E-33 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS11215 eee1ccb6bcf1978d3dde9d5bd5aac398 151 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:1.25.40.10 616 654 2.7E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SUPERFAMILY SSF56112 36 240 1.08E-15 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:1.25.40.120 177 439 0.0034 T 29-03-2018 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:1.25.40.10 792 889 1.3E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:3.30.200.20 31 165 4.8E-13 T 29-03-2018 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Pfam PF00069 Protein kinase domain 36 234 9.0E-12 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SMART SM00028 803 836 0.88 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SMART SM00028 602 635 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SMART SM00028 756 795 200.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SMART SM00028 837 870 90.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SMART SM00028 676 709 24.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SMART SM00028 565 598 160.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Pfam PF13432 Tetratricopeptide repeat 569 632 3.6E-4 T 29-03-2018 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:1.25.40.10 655 724 8.5E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SUPERFAMILY SSF48452 550 641 7.05E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 SUPERFAMILY SSF48452 682 869 7.05E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:1.25.40.10 525 615 2.1E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17005 9a0e8c9fb07bb7bb134427485b78841e 890 Gene3D G3DSA:1.25.40.10 725 791 3.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 SUPERFAMILY SSF51735 5 247 7.52E-87 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.0E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 3.0E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.0E-16 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 6.3E-5 T 29-03-2018 CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 7 247 7.8E-94 T 29-03-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 Pfam PF00106 short chain dehydrogenase 7 200 3.8E-68 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.8E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.8E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.8E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.8E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.8E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.8E-45 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 Gene3D G3DSA:3.40.50.720 1 41 2.3E-10 T 29-03-2018 CSW12_RS06120 e1189b3dc05e0bf1cad41f11fbaf650c 247 Gene3D G3DSA:3.40.50.720 42 247 2.7E-69 T 29-03-2018 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Pfam PF00364 Biotin-requiring enzyme 4 75 1.2E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:3.90.1170.30 2 45 7.1E-13 T 29-03-2018 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:3.90.1170.30 46 131 2.9E-4 T 29-03-2018 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 SUPERFAMILY SSF47005 119 161 8.89E-13 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Pfam PF02817 e3 binding domain 122 156 9.7E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 SUPERFAMILY SSF51230 3 92 1.44E-25 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:3.30.559.10 180 429 1.2E-91 T 29-03-2018 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 SUPERFAMILY SSF52777 190 426 7.56E-88 T 29-03-2018 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 199 426 1.1E-88 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS07890 a7ce9218b7b9a6ec937a6efbbd79d8c9 429 Gene3D G3DSA:4.10.320.10 132 169 5.5E-19 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS15060 e428bef5ca8c05159f376cb6c0ebd248 241 Pfam PF00005 ABC transporter 21 162 1.3E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS15060 e428bef5ca8c05159f376cb6c0ebd248 241 Gene3D G3DSA:3.40.50.300 2 238 4.2E-66 T 29-03-2018 CSW12_RS15060 e428bef5ca8c05159f376cb6c0ebd248 241 SUPERFAMILY SSF52540 4 223 8.95E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS15060 e428bef5ca8c05159f376cb6c0ebd248 241 SMART SM00382 30 209 3.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS15060 e428bef5ca8c05159f376cb6c0ebd248 241 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Pfam PF00689 Cation transporting ATPase, C-terminus 699 885 2.5E-51 T 29-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Gene3D G3DSA:2.70.150.10 12 230 1.9E-50 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF56784 327 347 5.77E-64 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF56784 469 718 5.77E-64 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 84 182 8.2E-21 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 465 559 2.6E-18 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 584 701 1.5E-36 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 219 355 3.3E-29 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Gene3D G3DSA:3.40.1110.10 292 519 4.1E-51 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 523 4.1E-43 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 544 4.1E-43 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 638 650 4.1E-43 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 633 4.1E-43 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 4.1E-43 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 4.1E-43 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF81665 230 323 1.57E-137 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF81665 664 887 1.57E-137 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF81665 2 115 1.57E-137 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 249 271 1.0E-8 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 322 343 1.0E-8 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 72 1.0E-19 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF81660 336 516 6.54E-53 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 628 9.2E-24 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Gene3D G3DSA:1.20.1110.10 526 888 1.9E-106 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 Pfam PF00122 E1-E2 ATPase 112 309 1.3E-55 T 29-03-2018 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SMART SM00831 3 77 1.3E-27 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS00925 00acec9d128bb7fea05630e4e10a2da3 888 SUPERFAMILY SSF81653 115 228 3.92E-30 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS19070 14878309b84ab364aa57fb173ebab026 305 SUPERFAMILY SSF53474 6 295 8.72E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS19070 14878309b84ab364aa57fb173ebab026 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 1.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS19070 14878309b84ab364aa57fb173ebab026 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 1.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS19070 14878309b84ab364aa57fb173ebab026 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 1.0E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS19070 14878309b84ab364aa57fb173ebab026 305 Gene3D G3DSA:3.40.50.1820 32 237 7.6E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS19070 14878309b84ab364aa57fb173ebab026 305 Pfam PF00561 alpha/beta hydrolase fold 35 147 3.8E-15 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS18090 ac855af9afefd8ddcd2886a9b9e1b427 200 Gene3D G3DSA:3.40.109.10 4 200 7.5E-33 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS18090 ac855af9afefd8ddcd2886a9b9e1b427 200 Pfam PF00881 Nitroreductase family 10 179 1.5E-19 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS18090 ac855af9afefd8ddcd2886a9b9e1b427 200 SUPERFAMILY SSF55469 5 199 1.31E-72 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Pfam PF13884 Chaperone of endosialidase 1469 1541 4.0E-9 T 29-03-2018 IPR030392 Intramolecular chaperone auto-processing domain CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.20.5.1070 829 882 8.6E-5 T 29-03-2018 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 29 351 1.2E-72 T 29-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.20.5.50 453 540 0.012 T 29-03-2018 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.10.10.10 1457 1603 1.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.20.5.50 999 1135 2.5E-9 T 29-03-2018 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.20.1480.30 547 626 0.024 T 29-03-2018 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.20.58.70 350 428 0.043 T 29-03-2018 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 Gene3D G3DSA:1.20.1270.70 771 828 0.17 T 29-03-2018 CSW12_RS02245 7563fd1ecdd37a8b3a15b9e698e53036 1611 SUPERFAMILY SSF57997 771 877 2.09E-5 T 29-03-2018 CSW12_RS12875 83455da7fdb159647730b1b9d8a9ea23 179 Pfam PF13523 Acetyltransferase (GNAT) domain 14 157 2.9E-28 T 29-03-2018 CSW12_RS12875 83455da7fdb159647730b1b9d8a9ea23 179 SUPERFAMILY SSF55729 4 176 1.4E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12875 83455da7fdb159647730b1b9d8a9ea23 179 Gene3D G3DSA:3.40.630.30 1 178 1.5E-25 T 29-03-2018 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 Gene3D G3DSA:3.10.290.10 326 418 1.5E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 7.6E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 7.6E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 7.6E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 7.6E-32 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 SUPERFAMILY SSF52374 2 323 1.5E-107 T 29-03-2018 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 Pfam PF01479 S4 domain 356 399 3.8E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 Gene3D G3DSA:3.40.50.620 4 223 1.1E-66 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 Gene3D G3DSA:1.10.240.10 224 325 2.0E-35 T 29-03-2018 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 46.761 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 SUPERFAMILY SSF55174 321 417 2.22E-24 T 29-03-2018 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 417 2.6E-139 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 3.2E-87 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22940 bc4c712a0a93790b4876da69be0ea0f8 418 SMART SM00363 353 414 2.4E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS23730 6f6a28323f80552cd0d398e9a39eff48 109 Pfam PF13240 zinc-ribbon domain 3 25 2.8E-6 T 29-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CSW12_RS23730 6f6a28323f80552cd0d398e9a39eff48 109 Gene3D G3DSA:2.20.28.20 1 29 2.4E-4 T 29-03-2018 CSW12_RS04215 b769bbf905534d84e31e4dd524f8dad2 577 Pfam PF00395 S-layer homology domain 35 77 1.1E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04215 b769bbf905534d84e31e4dd524f8dad2 577 Pfam PF00395 S-layer homology domain 171 214 4.5E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04215 b769bbf905534d84e31e4dd524f8dad2 577 Pfam PF00395 S-layer homology domain 111 155 1.5E-8 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04215 b769bbf905534d84e31e4dd524f8dad2 577 Pfam PF01841 Transglutaminase-like superfamily 329 423 4.0E-14 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS04215 b769bbf905534d84e31e4dd524f8dad2 577 SUPERFAMILY SSF54001 283 475 1.15E-26 T 29-03-2018 CSW12_RS04215 b769bbf905534d84e31e4dd524f8dad2 577 SMART SM00460 370 426 9.5E-8 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 Pfam PF00312 Ribosomal protein S15 8 88 7.0E-38 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-39 T 29-03-2018 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.161 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 SMART SM01387 8 88 2.1E-52 T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 Gene3D G3DSA:1.10.287.10 2 89 1.0E-36 T 29-03-2018 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 3.1E-42 T 29-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 29-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08740 e18d850046a6aade4438a2c3be2ebd28 89 SUPERFAMILY SSF47060 3 89 1.44E-36 T 29-03-2018 IPR009068 S15/NS1, RNA-binding CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Pfam PF03764 Elongation factor G, domain IV 444 538 2.0E-13 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Gene3D G3DSA:2.40.30.10 243 343 7.0E-18 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 SUPERFAMILY SSF54980 347 424 4.32E-13 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 SUPERFAMILY SSF54980 541 619 3.12E-8 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 SUPERFAMILY SSF50447 226 339 5.98E-22 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 SMART SM00889 423 538 6.4E-7 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Gene3D G3DSA:3.30.230.10 437 553 2.3E-11 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 SUPERFAMILY SSF54211 444 538 2.24E-13 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR00315 GTP-binding elongation factor signature 5 18 1.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.0E-16 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Pfam PF00679 Elongation factor G C-terminus 541 618 7.6E-9 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 159 2.7E-35 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Gene3D G3DSA:3.40.50.300 1 242 2.4E-46 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Pfam PF00009 Elongation factor Tu GTP binding domain 3 242 2.6E-61 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Pfam PF14492 Elongation Factor G, domain II 347 420 1.3E-8 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Gene3D G3DSA:3.30.70.870 344 436 1.6E-11 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 Gene3D G3DSA:3.30.70.240 554 626 1.1E-5 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 SUPERFAMILY SSF52540 4 242 2.53E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 270 296 1.9E-35 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 461 475 1.9E-35 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 510 527 1.9E-35 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 1.9E-35 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 216 238 1.9E-35 T 29-03-2018 CSW12_RS12525 9085c7b833d70d0c851375a56e0e9cad 647 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 476 498 1.9E-35 T 29-03-2018 CSW12_RS31220 ca7e71fdd917fe5dfc167aad919f77ab 313 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 309 1.2E-63 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS31220 ca7e71fdd917fe5dfc167aad919f77ab 313 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 245 8.9E-60 T 29-03-2018 CSW12_RS31220 ca7e71fdd917fe5dfc167aad919f77ab 313 Gene3D G3DSA:1.10.10.60 246 313 1.1E-10 T 29-03-2018 CSW12_RS30545 ca7e71fdd917fe5dfc167aad919f77ab 313 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 9 309 1.2E-63 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS30545 ca7e71fdd917fe5dfc167aad919f77ab 313 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 245 8.9E-60 T 29-03-2018 CSW12_RS30545 ca7e71fdd917fe5dfc167aad919f77ab 313 Gene3D G3DSA:1.10.10.60 246 313 1.1E-10 T 29-03-2018 CSW12_RS01880 7e2aa936a317ee9ce5a9ed2ec1eeeee3 500 PIRSF PIRSF005690 11 491 1.0E-169 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS01880 7e2aa936a317ee9ce5a9ed2ec1eeeee3 500 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 26 476 8.2E-173 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS01135 ea318890cbc501e03c6aef7370865a30 321 Gene3D G3DSA:3.90.25.10 191 321 1.5E-39 T 29-03-2018 CSW12_RS01135 ea318890cbc501e03c6aef7370865a30 321 SUPERFAMILY SSF51735 1 318 2.88E-84 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01135 ea318890cbc501e03c6aef7370865a30 321 Gene3D G3DSA:3.40.50.720 1 190 1.2E-37 T 29-03-2018 CSW12_RS01135 ea318890cbc501e03c6aef7370865a30 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 242 3.9E-60 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 TIGRFAM TIGR00492 alr: alanine racemase 8 374 2.5E-117 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 33 49 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 69 87 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 356 369 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 207 234 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 164 175 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 282 297 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 265 280 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 129 141 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 PRINTS PR00992 Alanine racemase signature 302 319 2.3E-64 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 Pfam PF00842 Alanine racemase, C-terminal domain 249 372 5.1E-41 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 SMART SM01005 249 374 3.2E-67 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 SUPERFAMILY SSF51419 14 250 7.2E-63 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 Pfam PF01168 Alanine racemase, N-terminal domain 14 234 3.3E-65 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 Gene3D G3DSA:2.40.37.10 232 383 9.8E-55 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 Hamap MF_01201 Alanine racemase. 7 374 34.281 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 Gene3D G3DSA:3.20.20.10 2 231 3.1E-48 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS28695 2a78c3b305fdd74f8b7c425d7678695b 389 SUPERFAMILY SSF50621 244 385 1.46E-49 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CSW12_RS20395 bb214655324a41e1675668584a565504 366 SMART SM00839 146 353 5.5E-70 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 PIRSF PIRSF000188 3 355 4.1E-166 T 29-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CSW12_RS20395 bb214655324a41e1675668584a565504 366 Gene3D G3DSA:3.40.50.10860 3 146 1.8E-52 T 29-03-2018 CSW12_RS20395 bb214655324a41e1675668584a565504 366 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 17 132 1.2E-26 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 76 89 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 220 349 2.1E-10 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 150 202 1.2E-5 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 Gene3D G3DSA:3.40.50.720 147 360 8.2E-39 T 29-03-2018 CSW12_RS20395 bb214655324a41e1675668584a565504 366 SUPERFAMILY SSF51735 143 349 1.3E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS20395 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 134 156 2.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 288 299 2.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 68 82 2.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 178 198 2.3E-22 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS20395 bb214655324a41e1675668584a565504 366 SUPERFAMILY SSF53223 6 145 8.64E-48 T 29-03-2018 CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 Gene3D G3DSA:1.20.58.220 448 540 7.0E-24 T 29-03-2018 CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 Pfam PF02690 Na+/Pi-cotransporter 18 153 1.0E-50 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 Pfam PF02690 Na+/Pi-cotransporter 148 253 1.3E-18 T 29-03-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 SUPERFAMILY SSF109755 336 539 1.05E-48 T 29-03-2018 CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 Pfam PF01895 PhoU domain 453 536 7.6E-19 T 29-03-2018 IPR026022 PhoU domain CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 Pfam PF01895 PhoU domain 348 434 5.9E-12 T 29-03-2018 IPR026022 PhoU domain CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 9 316 7.1E-74 T 29-03-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CSW12_RS03270 68defe6a3713f09a06fca46073d123be 551 Gene3D G3DSA:1.20.58.220 331 447 2.3E-20 T 29-03-2018 CSW12_RS16660 187dd61b146880c7c289de2f9b755098 297 SUPERFAMILY SSF82861 22 104 1.83E-11 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CSW12_RS16660 187dd61b146880c7c289de2f9b755098 297 SUPERFAMILY SSF82689 171 281 8.5E-9 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CSW12_RS16660 187dd61b146880c7c289de2f9b755098 297 Pfam PF00924 Mechanosensitive ion channel 65 272 8.6E-33 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CSW12_RS16660 187dd61b146880c7c289de2f9b755098 297 Gene3D G3DSA:2.30.30.60 121 170 1.8E-10 T 29-03-2018 CSW12_RS16660 187dd61b146880c7c289de2f9b755098 297 SUPERFAMILY SSF50182 106 169 7.85E-10 T 29-03-2018 IPR010920 LSM domain CSW12_RS16660 187dd61b146880c7c289de2f9b755098 297 Gene3D G3DSA:3.30.70.100 171 278 9.5E-11 T 29-03-2018 CSW12_RS29770 93bf179a089db56bf0188d8770b99a45 364 SUPERFAMILY SSF48452 92 307 5.48E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS29770 93bf179a089db56bf0188d8770b99a45 364 Gene3D G3DSA:1.25.40.10 3 143 8.6E-32 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS29770 93bf179a089db56bf0188d8770b99a45 364 Gene3D G3DSA:1.25.40.10 144 364 1.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20380 05f4e1f18a5d4bf45a45691d1b61f11d 333 Pfam PF00676 Dehydrogenase E1 component 24 323 4.0E-105 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CSW12_RS20380 05f4e1f18a5d4bf45a45691d1b61f11d 333 SUPERFAMILY SSF52518 10 333 5.4E-104 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS20380 05f4e1f18a5d4bf45a45691d1b61f11d 333 Gene3D G3DSA:3.40.50.970 2 333 2.8E-85 T 29-03-2018 CSW12_RS00945 6ae12649678218b2b447fbed7935bdf9 288 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 278 1.4E-56 T 29-03-2018 IPR017039 Virulence factor BrkB CSW12_RS00945 6ae12649678218b2b447fbed7935bdf9 288 PIRSF PIRSF035875 1 288 3.0E-91 T 29-03-2018 IPR017039 Virulence factor BrkB CSW12_RS00945 6ae12649678218b2b447fbed7935bdf9 288 Pfam PF03631 Virulence factor BrkB 26 277 2.4E-67 T 29-03-2018 IPR017039 Virulence factor BrkB CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1172 2.3E-64 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Gene3D G3DSA:1.20.5.340 751 864 0.0022 T 29-03-2018 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Gene3D G3DSA:1.10.287.620 173 332 1.7E-5 T 29-03-2018 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Gene3D G3DSA:1.20.5.730 661 750 0.0048 T 29-03-2018 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1181 24.305 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 SUPERFAMILY SSF52540 2 207 1.9E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 SUPERFAMILY SSF52540 980 1174 1.9E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1179 0.0 T 29-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 SMART SM00968 519 638 6.0E-40 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Gene3D G3DSA:3.40.50.300 870 1189 7.2E-29 T 29-03-2018 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Gene3D G3DSA:1.20.120.330 368 530 0.0013 T 29-03-2018 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 638 1.6E-29 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 Gene3D G3DSA:3.40.50.300 1 172 1.8E-39 T 29-03-2018 CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 PIRSF PIRSF005719 1 1186 0.0 T 29-03-2018 IPR024704 Structural maintenance of chromosomes protein CSW12_RS08535 e0ed85756e1cf74053bae53d8d5deeb3 1189 SUPERFAMILY SSF75553 484 687 3.14E-56 T 29-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 SUPERFAMILY SSF53448 4 224 2.19E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 SUPERFAMILY SSF53448 285 301 2.19E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 Gene3D G3DSA:3.90.550.10 1 154 5.5E-15 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 Gene3D G3DSA:2.160.10.10 228 344 9.2E-18 T 29-03-2018 CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 SUPERFAMILY SSF51161 230 324 6.94E-16 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 289 322 5.7E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 Gene3D G3DSA:3.90.550.10 155 227 1.7E-4 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24085 d064d728c70aea8e8f606cfc38387523 344 Pfam PF00483 Nucleotidyl transferase 8 149 1.3E-9 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 22 304 5.8E-21 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 SUPERFAMILY SSF51735 100 278 1.03E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 Gene3D G3DSA:3.40.50.720 114 279 1.9E-41 T 29-03-2018 CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 Gene3D G3DSA:3.40.50.720 1 113 1.0E-25 T 29-03-2018 CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 273 3.8E-47 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CSW12_RS07590 2a66ba3c4dc25791994a85fb5d9df655 306 SUPERFAMILY SSF52283 1 126 1.63E-22 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 431 29.636 T 29-03-2018 IPR026593 Protein translocase subunit SecY CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 Gene3D G3DSA:1.10.3370.10 1 433 1.5E-154 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 271 290 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 311 333 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 400 418 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PRINTS PR00303 Preprotein translocase SecY subunit signature 366 384 1.3E-101 T 29-03-2018 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 PIRSF PIRSF004557 1 433 2.1E-130 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 SUPERFAMILY SSF103491 1 422 1.31E-129 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 427 2.9E-147 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 Pfam PF00344 SecY translocase 68 415 2.9E-114 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS28085 84895a7e7b893e1e7a2c487411595b69 433 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS06035 315c696697092c677984214d72640f61 324 SUPERFAMILY SSF51004 27 313 1.2E-45 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CSW12_RS06035 315c696697092c677984214d72640f61 324 Gene3D G3DSA:2.130.10.10 15 117 3.3E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS06035 315c696697092c677984214d72640f61 324 Gene3D G3DSA:2.130.10.10 118 222 2.4E-13 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS06035 315c696697092c677984214d72640f61 324 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 283 315 1.8E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS06035 315c696697092c677984214d72640f61 324 Gene3D G3DSA:2.130.10.10 223 316 2.0E-9 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 Gene3D G3DSA:3.40.430.10 125 366 8.0E-75 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 357 6.7E-73 T 29-03-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 PIRSF PIRSF006769 1 362 2.5E-134 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 SUPERFAMILY SSF53597 147 356 2.57E-62 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 Gene3D G3DSA:3.40.140.10 1 124 3.2E-31 T 29-03-2018 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 Pfam PF01872 RibD C-terminal domain 147 354 3.7E-59 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 3.3E-21 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 355 1.0E-124 T 29-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CSW12_RS20095 70e54d21811f3a00ca460fb1338772eb 370 SUPERFAMILY SSF53927 3 145 1.84E-44 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Pfam PF13426 PAS domain 475 569 5.6E-9 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Pfam PF07694 5TMR of 5TMR-LYT 37 136 9.0E-7 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Gene3D G3DSA:3.30.565.10 649 801 4.1E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00091 454 527 0.0051 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00091 321 389 2.5E-5 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Pfam PF08448 PAS fold 230 310 3.6E-6 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Pfam PF08448 PAS fold 332 437 1.6E-16 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00388 585 649 7.6E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SUPERFAMILY SSF55785 441 568 5.98E-20 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 729 743 5.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 782 795 5.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 747 757 5.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 776 5.1E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SUPERFAMILY SSF55785 217 316 4.61E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SUPERFAMILY SSF55874 646 796 6.55E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 694 795 3.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 450 576 7.6E-18 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 441 2.4E-27 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Gene3D G3DSA:3.30.450.20 175 319 8.2E-14 T 29-03-2018 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SUPERFAMILY SSF47384 578 646 1.06E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00086 269 309 420.0 T 29-03-2018 IPR001610 PAC motif CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00086 393 435 2.7E-4 T 29-03-2018 IPR001610 PAC motif CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00086 530 570 4.4 T 29-03-2018 IPR001610 PAC motif CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Gene3D G3DSA:3.30.450.20 320 444 3.7E-26 T 29-03-2018 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SMART SM00387 691 798 9.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Gene3D G3DSA:3.30.450.20 445 582 5.7E-22 T 29-03-2018 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 SUPERFAMILY SSF55785 306 433 6.98E-23 T 29-03-2018 IPR000014 PAS domain CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Gene3D G3DSA:1.10.287.130 583 645 2.2E-11 T 29-03-2018 CSW12_RS15400 72359bd76fd38ea5ecce31d5403434b8 801 Pfam PF00512 His Kinase A (phospho-acceptor) domain 587 645 2.1E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS16645 655ac4ee01a17bcde2e2a0b8660028a5 284 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 78 3.9E-20 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CSW12_RS16645 655ac4ee01a17bcde2e2a0b8660028a5 284 SUPERFAMILY SSF53697 94 281 5.75E-47 T 29-03-2018 CSW12_RS16645 655ac4ee01a17bcde2e2a0b8660028a5 284 Pfam PF01380 SIS domain 130 258 3.7E-24 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CSW12_RS16645 655ac4ee01a17bcde2e2a0b8660028a5 284 Gene3D G3DSA:3.40.50.10490 98 283 3.0E-43 T 29-03-2018 CSW12_RS16645 655ac4ee01a17bcde2e2a0b8660028a5 284 Gene3D G3DSA:1.10.10.10 4 97 1.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16645 655ac4ee01a17bcde2e2a0b8660028a5 284 SUPERFAMILY SSF46689 8 80 2.69E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF56801 431 987 8.77E-165 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1549 1943 8.1E-135 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 488 894 6.6E-141 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF00550 Phosphopantetheine attachment site 2026 2089 1.4E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF00550 Phosphopantetheine attachment site 977 1040 5.9E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:2.30.38.10 781 860 7.0E-23 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF52777 1249 1512 4.89E-64 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.40.50.980 458 615 3.2E-48 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.40.50.980 1519 1676 5.3E-50 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.30.300.30 1914 2030 1.0E-40 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.30.300.30 865 981 8.0E-40 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.40.50.980 1677 1827 1.8E-29 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.40.50.980 616 780 4.0E-39 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF52777 10 190 1.89E-41 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:2.30.38.10 1830 1912 7.2E-25 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 ProSitePatterns PS00455 Putative AMP-binding domain signature. 609 620 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF47336 969 1076 2.36E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.30.559.10 4 208 2.0E-35 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:3.30.559.10 1044 1266 2.1E-46 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF00668 Condensation domain 6 447 6.6E-94 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF00668 Condensation domain 1061 1508 5.9E-120 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF13193 AMP-binding enzyme C-terminal domain 1927 1998 8.0E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF13193 AMP-binding enzyme C-terminal domain 878 949 3.5E-9 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:1.10.1200.10 982 1043 4.6E-23 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF52777 191 454 2.56E-54 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1671 1682 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF52777 1066 1243 1.02E-47 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF56801 1485 2036 9.94E-162 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Gene3D G3DSA:1.10.1200.10 2031 2117 1.7E-22 T 29-03-2018 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SMART SM00823 Phosphopantetheine attachment site 2024 2093 0.074 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SMART SM00823 Phosphopantetheine attachment site 975 1044 1.4E-4 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 SUPERFAMILY SSF47336 2016 2090 5.5E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF00501 AMP-binding enzyme 467 870 1.7E-106 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 Pfam PF00501 AMP-binding enzyme 1528 1919 1.7E-103 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15530 b6c3e011ed5a99a71627df283234efc5 2156 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2048 2063 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS16760 31c079b422f71ea2a8336efa109cbd19 215 Gene3D G3DSA:3.40.109.10 3 215 1.4E-47 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS16760 31c079b422f71ea2a8336efa109cbd19 215 Pfam PF00881 Nitroreductase family 10 193 3.1E-36 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS16760 31c079b422f71ea2a8336efa109cbd19 215 SUPERFAMILY SSF55469 4 66 1.44E-49 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS16760 31c079b422f71ea2a8336efa109cbd19 215 SUPERFAMILY SSF55469 95 213 1.44E-49 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.3E-35 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 1.1E-57 T 29-03-2018 CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 SUPERFAMILY SSF51735 5 253 8.32E-78 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 Gene3D G3DSA:3.40.50.720 1 37 1.5E-9 T 29-03-2018 CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 Gene3D G3DSA:3.40.50.720 38 254 5.9E-61 T 29-03-2018 CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 5.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 5.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11955 d743846d7889584b17fcb1c083b66696 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 291 9.1E-101 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 PRINTS PR00990 Ribokinase signature 33 52 5.5E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 PRINTS PR00990 Ribokinase signature 172 187 5.5E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 PRINTS PR00990 Ribokinase signature 6 27 5.5E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 PRINTS PR00990 Ribokinase signature 104 117 5.5E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 PRINTS PR00990 Ribokinase signature 209 220 5.5E-33 T 29-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 238 251 - T 29-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 Hamap MF_01987 Ribokinase [rbsK]. 2 293 24.641 T 29-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 SUPERFAMILY SSF53613 4 292 8.73E-78 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 Gene3D G3DSA:3.40.1190.20 1 294 4.6E-74 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS02030 b5ede42430ead10a1db22ba710240b69 298 Pfam PF00294 pfkB family carbohydrate kinase 1 286 2.2E-69 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CSW12_RS16845 9b1abee28290ce58fc25f4794d39078a 211 SUPERFAMILY SSF52218 1 211 4.19E-54 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS16845 9b1abee28290ce58fc25f4794d39078a 211 Gene3D G3DSA:3.40.50.360 2 211 2.7E-41 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS16845 9b1abee28290ce58fc25f4794d39078a 211 Pfam PF02525 Flavodoxin-like fold 2 206 1.1E-47 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS16845 9b1abee28290ce58fc25f4794d39078a 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 30.03 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Gene3D G3DSA:1.25.40.10 284 361 3.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 SUPERFAMILY SSF48452 196 347 4.02E-15 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Gene3D G3DSA:1.25.40.10 177 244 6.2E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Pfam PF00535 Glycosyl transferase family 2 10 147 3.9E-18 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Gene3D G3DSA:1.25.40.10 245 283 9.9E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Gene3D G3DSA:3.90.550.10 4 176 1.1E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 SUPERFAMILY SSF53448 8 160 3.0E-24 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Pfam PF13176 Tetratricopeptide repeat 235 263 0.0067 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS05590 b251f3e135295112a0d631d894e7b5da 365 Pfam PF13181 Tetratricopeptide repeat 269 295 9.9E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 PIRSF PIRSF000094 1 256 3.2E-103 T 29-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.4E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 SUPERFAMILY SSF51735 5 254 9.74E-68 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 Gene3D G3DSA:3.40.50.720 2 255 1.4E-48 T 29-03-2018 CSW12_RS05630 6eb5ebf4c57038968b38ce8fadd6354e 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.5E-87 T 29-03-2018 CSW12_RS11680 4cae4009d811e5ef7b7047054fe56780 319 SUPERFAMILY SSF103365 2 318 1.31E-80 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CSW12_RS11680 4cae4009d811e5ef7b7047054fe56780 319 Pfam PF01139 tRNA-splicing ligase RtcB 53 317 9.2E-55 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 Pfam PF03466 LysR substrate binding domain 98 288 8.7E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 Gene3D G3DSA:1.10.10.10 1 83 3.2E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 SUPERFAMILY SSF53850 99 292 2.17E-37 T 29-03-2018 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 Gene3D G3DSA:3.40.190.10 178 262 1.7E-21 T 29-03-2018 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 SUPERFAMILY SSF46785 1 85 1.27E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 3.7E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-10 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25830 ef6a9419cb130ae7ffa0164ef9fee0a5 294 Gene3D G3DSA:3.40.190.10 91 177 2.6E-18 T 29-03-2018 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 Pfam PF08453 Peptidase family M9 N-terminal 97 278 6.3E-56 T 29-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 Pfam PF00801 PKD domain 796 847 6.0E-13 T 29-03-2018 IPR000601 PKD domain CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 Pfam PF01752 Collagenase 302 628 9.6E-83 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 Gene3D G3DSA:2.60.40.10 765 855 2.4E-25 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 449 463 1.2E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 529 544 1.2E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 503 521 1.2E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 466 482 1.2E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 163 181 1.2E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 SUPERFAMILY SSF89260 863 970 1.19E-29 T 29-03-2018 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 SMART SM00089 775 857 7.7E-25 T 29-03-2018 IPR022409 PKD/Chitinase domain CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 Gene3D G3DSA:2.60.120.380 856 971 1.0E-18 T 29-03-2018 CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 SUPERFAMILY SSF49299 771 856 1.96E-23 T 29-03-2018 IPR000601 PKD domain CSW12_RS10115 aae5c5224c3e4c7506c2be27cca6fcce 971 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 892 957 2.0E-5 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 PIRSF PIRSF001220 1 324 1.1E-97 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 Pfam PF00710 Asparaginase, N-terminal 3 191 1.7E-60 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 SMART SM00870 3 318 2.0E-144 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 SUPERFAMILY SSF53774 2 322 2.62E-103 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 1.8E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.8E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 1.8E-18 T 29-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 Gene3D G3DSA:3.40.50.40 207 323 8.3E-33 T 29-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 29-03-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 PIRSF PIRSF500176 1 324 1.9E-93 T 29-03-2018 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 Gene3D G3DSA:3.40.50.1170 1 206 1.2E-56 T 29-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CSW12_RS07070 247d219c850ce85025bdeb0cc5946843 324 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 81 91 - T 29-03-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 Pfam PF04397 LytTr DNA-binding domain 235 333 6.5E-25 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 SUPERFAMILY SSF52540 16 199 1.23E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 SMART SM00850 235 334 2.3E-31 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 Gene3D G3DSA:2.40.50.40 230 295 5.4E-18 T 29-03-2018 CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 PIRSF PIRSF036612 1 335 5.3E-156 T 29-03-2018 IPR012046 LytTR transcriptional regulator with ABC transporter ATP-binding domain CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 Gene3D G3DSA:3.40.50.300 7 229 7.2E-24 T 29-03-2018 CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 Pfam PF00005 ABC transporter 18 148 8.6E-10 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26200 a1b316b0fa061d13566342adb5628ad2 335 Gene3D G3DSA:2.20.25.10 296 334 1.3E-5 T 29-03-2018 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Gene3D G3DSA:2.40.50.100 48 116 6.3E-7 T 29-03-2018 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 2 418 5.2E-173 T 29-03-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Gene3D G3DSA:3.30.559.10 176 417 4.2E-89 T 29-03-2018 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 SUPERFAMILY SSF51230 1 94 4.95E-25 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Gene3D G3DSA:3.90.1170.30 1 47 2.1E-13 T 29-03-2018 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 SUPERFAMILY SSF47005 119 162 9.02E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Gene3D G3DSA:4.10.320.10 117 175 9.2E-17 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 187 417 2.3E-80 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Pfam PF00364 Biotin-requiring enzyme 3 75 5.1E-20 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 Pfam PF02817 e3 binding domain 125 159 5.0E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CSW12_RS05835 27c259f804e90080fc9b6cc156f93954 419 SUPERFAMILY SSF52777 188 417 4.45E-87 T 29-03-2018 CSW12_RS15390 a910f46b1472b3be89d2c6d70b8d6ce3 360 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 351 2.3E-50 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS15390 a910f46b1472b3be89d2c6d70b8d6ce3 360 Pfam PF03845 Spore germination protein 9 325 3.0E-82 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 SMART SM00530 9 64 2.5E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 Pfam PF01381 Helix-turn-helix 13 61 1.3E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 Pfam PF07883 Cupin domain 110 180 1.1E-15 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 SUPERFAMILY SSF51182 57 184 4.8E-24 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 SUPERFAMILY SSF47413 4 69 3.22E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 Gene3D G3DSA:1.10.260.40 1 79 2.1E-18 T 29-03-2018 CSW12_RS15970 ead9d4183fbe329f08083321041d3b4e 186 Gene3D G3DSA:2.60.120.10 80 184 1.3E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 SUPERFAMILY SSF55424 350 472 2.58E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 8.3E-38 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 Gene3D G3DSA:3.40.50.720 173 341 4.2E-32 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 3.0E-177 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 SUPERFAMILY SSF51905 1 377 3.05E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PIRSF PIRSF000350 1 469 8.8E-86 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 Gene3D G3DSA:3.50.50.60 1 172 1.0E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-36 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.7E-36 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.7E-36 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.7E-36 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.7E-36 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 3.2E-69 T 29-03-2018 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 Gene3D G3DSA:3.30.390.30 342 470 4.0E-41 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS20385 bb465ab4e22be2b6ec1176df25f77548 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 2.5E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS18045 5ac9286404d572c9b071b84c2860c794 290 PIRSF PIRSF000812 1 285 1.4E-124 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase CSW12_RS18045 5ac9286404d572c9b071b84c2860c794 290 SUPERFAMILY SSF81631 137 280 8.63E-57 T 29-03-2018 CSW12_RS18045 5ac9286404d572c9b071b84c2860c794 290 Gene3D G3DSA:3.30.460.10 9 150 1.0E-43 T 29-03-2018 CSW12_RS18045 5ac9286404d572c9b071b84c2860c794 290 Pfam PF04439 Streptomycin adenylyltransferase 1 279 6.5E-128 T 29-03-2018 IPR007530 Aminoglycoside 6-adenylyltransferase CSW12_RS18045 5ac9286404d572c9b071b84c2860c794 290 SUPERFAMILY SSF81301 1 133 7.68E-49 T 29-03-2018 CSW12_RS18045 5ac9286404d572c9b071b84c2860c794 290 Gene3D G3DSA:1.20.120.330 151 281 2.8E-54 T 29-03-2018 CSW12_RS24505 54a027d14f0bed4fbab13851382563e9 219 SMART SM00382 22 205 4.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS24505 54a027d14f0bed4fbab13851382563e9 219 SUPERFAMILY SSF52540 7 208 1.81E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS24505 54a027d14f0bed4fbab13851382563e9 219 Gene3D G3DSA:3.40.50.300 9 215 7.1E-57 T 29-03-2018 CSW12_RS24505 54a027d14f0bed4fbab13851382563e9 219 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS24505 54a027d14f0bed4fbab13851382563e9 219 Pfam PF00005 ABC transporter 18 156 4.9E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 Gene3D G3DSA:3.30.360.10 176 317 2.5E-46 T 29-03-2018 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 146 2.0E-6 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 Gene3D G3DSA:3.40.50.720 1 175 3.2E-19 T 29-03-2018 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 SUPERFAMILY SSF55347 155 317 1.77E-41 T 29-03-2018 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 SUPERFAMILY SSF51735 3 176 5.73E-12 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 PIRSF PIRSF036497 1 341 2.2E-106 T 29-03-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS14690 57ac7e038d7bb276f26e880fbd2072c4 341 Pfam PF00742 Homoserine dehydrogenase 158 334 5.5E-49 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS02775 b644a2da2865419046172262f89585d8 85 SMART SM00899 7 79 1.8E-20 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CSW12_RS02775 b644a2da2865419046172262f89585d8 85 Pfam PF04023 FeoA domain 8 76 4.5E-19 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CSW12_RS02775 b644a2da2865419046172262f89585d8 85 Gene3D G3DSA:2.30.30.90 5 76 2.0E-20 T 29-03-2018 CSW12_RS02775 b644a2da2865419046172262f89585d8 85 SUPERFAMILY SSF50037 10 76 1.03E-18 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 SUPERFAMILY SSF55136 133 300 1.15E-31 T 29-03-2018 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 Gene3D G3DSA:3.20.80.10 120 298 1.5E-45 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 SMART SM00342 22 105 4.2E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 59 101 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 SUPERFAMILY SSF46689 58 115 1.34E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 SMART SM00871 133 298 1.3E-39 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 Pfam PF12833 Helix-turn-helix domain 28 107 1.8E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 SUPERFAMILY SSF46689 7 56 8.96E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 Pfam PF14526 Integron-associated effector binding protein 136 297 4.9E-31 T 29-03-2018 IPR029441 Integron-associated effector binding protein CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 Gene3D G3DSA:1.10.10.60 1 58 3.4E-13 T 29-03-2018 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 74 89 8.2E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 89 105 8.2E-7 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS04840 ce70fb5ffa73d5484b0ec538716b626e 300 Gene3D G3DSA:1.10.10.60 59 119 1.7E-16 T 29-03-2018 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF158472 197 244 4.58E-9 T 29-03-2018 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF55874 420 587 2.1E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:1.10.287.130 359 425 1.0E-17 T 29-03-2018 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Pfam PF00672 HAMP domain 197 243 6.7E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:3.30.450.20 234 358 5.7E-14 T 29-03-2018 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 2.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 2.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 568 2.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 574 587 2.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF55785 243 356 7.44E-8 T 29-03-2018 IPR000014 PAS domain CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SUPERFAMILY SSF47384 348 432 4.51E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:3.30.450.20 31 167 3.8E-5 T 29-03-2018 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00304 196 248 1.2E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00091 255 324 1.8E-4 T 29-03-2018 IPR000014 PAS domain CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00388 364 431 5.4E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 588 1.3E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Gene3D G3DSA:3.30.565.10 426 590 2.6E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 SMART SM00387 477 590 4.8E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06975 4d792e56912e2e2fcecd0c0f4b82a9ff 591 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 431 1.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1363 1508 1.5E-30 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 945 1.5E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 SUPERFAMILY SSF52777 188 421 9.0E-31 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:3.30.559.10 1 189 4.9E-13 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 SUPERFAMILY SSF56801 415 984 8.24E-171 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 SUPERFAMILY SSF52777 9 182 7.11E-24 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 601 612 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 479 890 6.7E-144 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 SUPERFAMILY SSF52777 1054 1231 3.11E-37 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 SUPERFAMILY SSF52777 1242 1486 3.56E-35 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:3.40.50.980 451 605 7.6E-51 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:3.30.559.10 1035 1242 5.6E-27 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:3.30.300.30 861 976 1.9E-39 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Pfam PF00550 Phosphopantetheine attachment site 974 1033 7.1E-12 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Pfam PF00668 Condensation domain 1050 1488 6.1E-85 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Pfam PF00668 Condensation domain 4 436 2.6E-84 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Pfam PF00501 AMP-binding enzyme 458 866 5.1E-112 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:3.40.50.980 606 772 1.4E-38 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 ProSitePatterns PS00012 Phosphopantetheine attachment site. 995 1010 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:1.10.1200.10 977 1034 1.4E-16 T 29-03-2018 CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 SUPERFAMILY SSF47336 965 1033 7.49E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15535 5b221f370622086ff91c9aec76e27c78 1518 Gene3D G3DSA:2.30.38.10 775 859 1.0E-24 T 29-03-2018 CSW12_RS06385 b18ecc7ab96b02b7c3fde6f8d299f457 306 PIRSF PIRSF028757 1 299 5.4E-89 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS06385 b18ecc7ab96b02b7c3fde6f8d299f457 306 Gene3D G3DSA:3.50.30.60 152 300 1.9E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS06385 b18ecc7ab96b02b7c3fde6f8d299f457 306 SUPERFAMILY SSF52317 1 157 7.32E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS06385 b18ecc7ab96b02b7c3fde6f8d299f457 306 Pfam PF02016 LD-carboxypeptidase 13 287 4.6E-81 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS06385 b18ecc7ab96b02b7c3fde6f8d299f457 306 SUPERFAMILY SSF141986 142 293 1.83E-42 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS06385 b18ecc7ab96b02b7c3fde6f8d299f457 306 Gene3D G3DSA:3.40.50.10740 1 151 1.1E-55 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 SUPERFAMILY SSF51735 1 153 1.35E-47 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 154 1.1E-43 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 167 276 1.2E-23 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 SUPERFAMILY SSF48179 165 295 8.16E-41 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 Gene3D G3DSA:1.10.1040.10 169 297 8.6E-38 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 SMART SM01350 167 298 4.5E-6 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 298 4.2E-133 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 59 88 8.4E-28 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 156 184 8.4E-28 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 231 258 8.4E-28 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 21 8.4E-28 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS16610 cf7542b20c0d71df72734d9571da65d7 298 Gene3D G3DSA:3.40.50.720 1 168 9.0E-29 T 29-03-2018 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 Gene3D G3DSA:3.40.50.2300 1 139 2.0E-28 T 29-03-2018 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 SMART SM00448 2 113 2.6E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 SUPERFAMILY SSF52172 2 131 1.99E-30 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 Pfam PF00072 Response regulator receiver domain 4 113 7.3E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 SMART SM00850 148 245 2.1E-37 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 Pfam PF04397 LytTr DNA-binding domain 149 244 6.0E-32 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 Gene3D G3DSA:2.40.50.40 140 208 2.1E-15 T 29-03-2018 CSW12_RS26980 343de73fd69494461e33fb2183a0c9c9 246 Gene3D G3DSA:2.20.25.10 209 245 3.4E-19 T 29-03-2018 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 132 165 260.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 213 246 52.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 92 125 64.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 SMART SM00028 173 206 11.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 SUPERFAMILY SSF48452 130 266 8.54E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 Pfam PF13424 Tetratricopeptide repeat 177 236 2.5E-7 T 29-03-2018 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 Gene3D G3DSA:1.25.40.10 6 144 2.1E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS18905 ec668affb0102f122e889817fe3ac5eb 364 Gene3D G3DSA:1.25.40.10 149 364 3.6E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS27685 313fbb9edaf2203226ddb6513b1cec71 262 SUPERFAMILY SSF53067 124 253 1.44E-41 T 29-03-2018 CSW12_RS27685 313fbb9edaf2203226ddb6513b1cec71 262 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 2.3E-87 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CSW12_RS27685 313fbb9edaf2203226ddb6513b1cec71 262 Pfam PF03309 Type III pantothenate kinase 3 206 4.4E-75 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CSW12_RS27685 313fbb9edaf2203226ddb6513b1cec71 262 SUPERFAMILY SSF53067 1 122 9.81E-40 T 29-03-2018 CSW12_RS27685 313fbb9edaf2203226ddb6513b1cec71 262 Gene3D G3DSA:3.30.420.40 89 262 9.5E-65 T 29-03-2018 CSW12_RS27685 313fbb9edaf2203226ddb6513b1cec71 262 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 38.173 T 29-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CSW12_RS16280 fe4d97be4034558cfdbc358e96a3432f 302 Gene3D G3DSA:3.20.20.60 10 299 3.4E-87 T 29-03-2018 CSW12_RS16280 fe4d97be4034558cfdbc358e96a3432f 302 ProSitePatterns PS00161 Isocitrate lyase signature. 127 132 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CSW12_RS16280 fe4d97be4034558cfdbc358e96a3432f 302 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 256 1.5E-53 T 29-03-2018 CSW12_RS16280 fe4d97be4034558cfdbc358e96a3432f 302 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 16 295 2.7E-130 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CSW12_RS16280 fe4d97be4034558cfdbc358e96a3432f 302 SUPERFAMILY SSF51621 9 294 4.49E-99 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS16280 fe4d97be4034558cfdbc358e96a3432f 302 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 12 296 48.521 T 29-03-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 CSW12_RS20055 f111d4e8ea20a37d591bf39b4aa8da69 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 7.0E-263 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CSW12_RS20055 f111d4e8ea20a37d591bf39b4aa8da69 492 SUPERFAMILY SSF52540 21 236 2.83E-14 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20055 f111d4e8ea20a37d591bf39b4aa8da69 492 Gene3D G3DSA:3.40.50.300 6 278 7.1E-12 T 29-03-2018 CSW12_RS20055 f111d4e8ea20a37d591bf39b4aa8da69 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 1.7E-226 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CSW12_RS20055 f111d4e8ea20a37d591bf39b4aa8da69 492 PIRSF PIRSF007466 1 492 2.7E-274 T 29-03-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 2.7E-105 T 29-03-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 7.1E-5 T 29-03-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 Gene3D G3DSA:3.40.30.10 2 154 9.1E-32 T 29-03-2018 CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 SUPERFAMILY SSF52833 1 187 9.78E-55 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 PIRSF PIRSF000239 1 187 1.5E-49 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 Gene3D G3DSA:3.30.1020.10 155 183 6.3E-7 T 29-03-2018 CSW12_RS00555 412d226f80e22b3919f7badfda5b5689 187 Pfam PF00578 AhpC/TSA family 4 133 3.6E-32 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 348 2.3E-101 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 SUPERFAMILY SSF52540 55 344 8.08E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 Gene3D G3DSA:3.40.50.300 1 195 4.9E-33 T 29-03-2018 CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 29-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 SMART SM00487 12 207 5.2E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 Pfam PF00271 Helicase conserved C-terminal domain 227 323 3.4E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 Pfam PF00270 DEAD/DEAH box helicase 18 176 1.3E-21 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 Gene3D G3DSA:3.40.50.300 199 477 5.4E-45 T 29-03-2018 CSW12_RS07015 29a1aea0758d7ccc7c18c59cf6e2d064 509 SMART SM00490 241 323 8.0E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 Gene3D G3DSA:3.40.50.880 1 223 1.4E-40 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 202 2.7E-47 T 29-03-2018 CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 SUPERFAMILY SSF52317 2 219 2.08E-78 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 3.9E-99 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 PIRSF PIRSF001586 1 222 1.8E-93 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 SMART SM01211 1 219 5.2E-139 T 29-03-2018 CSW12_RS00045 a359ac91237206054d63baf95bd3130d 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 46.319 T 29-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 94 111 0.18 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 131 166 6.9E-12 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 SUPERFAMILY SSF51161 2 185 4.85E-56 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 SMART SM01266 6 60 5.2E-21 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 Pfam PF12464 Maltose acetyltransferase 8 59 5.8E-15 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CSW12_RS22965 4ee9df419decf9d79f47b506940d11e9 186 Gene3D G3DSA:2.160.10.10 3 186 8.2E-55 T 29-03-2018 CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 SUPERFAMILY SSF46785 7 78 3.67E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 Gene3D G3DSA:3.90.1150.10 379 476 1.0E-18 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 Pfam PF00155 Aminotransferase class I and II 145 468 1.6E-34 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.1E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 Gene3D G3DSA:1.10.10.10 1 77 2.8E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 SUPERFAMILY SSF53383 86 473 1.06E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 SMART SM00345 17 76 1.8E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14000 35e27c30449e52bcb289383965b707d0 477 Gene3D G3DSA:3.40.640.10 128 378 8.9E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 220 2.8E-70 T 29-03-2018 IPR010016 KipI family CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 SUPERFAMILY SSF50891 98 227 4.17E-45 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 209 7.4E-75 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 SMART SM00796 1 211 8.0E-97 T 29-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 Gene3D G3DSA:3.30.1360.40 1 93 1.8E-21 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 SUPERFAMILY SSF160467 2 102 5.1E-17 T 29-03-2018 CSW12_RS12295 b6c98794fcf9c06db2131d10d0f909a8 237 Gene3D G3DSA:2.40.100.10 95 229 1.6E-48 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS12370 b6d7232a851ae7b0da1b59341ff7f44f 235 SUPERFAMILY SSF52540 3 223 1.44E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12370 b6d7232a851ae7b0da1b59341ff7f44f 235 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS12370 b6d7232a851ae7b0da1b59341ff7f44f 235 SMART SM00382 32 218 5.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS12370 b6d7232a851ae7b0da1b59341ff7f44f 235 Pfam PF00005 ABC transporter 23 169 3.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS12370 b6d7232a851ae7b0da1b59341ff7f44f 235 Gene3D G3DSA:3.40.50.300 1 223 3.7E-62 T 29-03-2018 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Gene3D G3DSA:3.40.50.300 206 392 3.2E-25 T 29-03-2018 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 SUPERFAMILY SSF56024 39 181 1.96E-17 T 29-03-2018 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Pfam PF00271 Helicase conserved C-terminal domain 454 546 5.6E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Pfam PF13091 PLD-like domain 48 177 6.9E-18 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Gene3D G3DSA:3.30.870.10 17 185 2.4E-19 T 29-03-2018 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Pfam PF04851 Type III restriction enzyme, res subunit 224 375 7.3E-34 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 SMART SM00490 467 548 8.8E-16 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Pfam PF11907 Domain of unknown function (DUF3427) 687 960 1.1E-83 T 29-03-2018 IPR021835 Protein of unknown function DUF3427 CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 SMART SM00487 222 402 8.1E-9 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 SUPERFAMILY SSF52540 271 569 1.46E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03915 b7c9a77564f6e60c88fee941d49d096a 966 Gene3D G3DSA:3.40.50.300 423 908 4.4E-25 T 29-03-2018 CSW12_RS11935 4b84482c07f88f8b9ce454c2fc11e016 130 Gene3D G3DSA:3.10.180.10 1 130 9.2E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS11935 4b84482c07f88f8b9ce454c2fc11e016 130 SUPERFAMILY SSF54593 1 127 6.18E-29 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS11935 4b84482c07f88f8b9ce454c2fc11e016 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 125 4.1E-14 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS01775 2bb2ba641a9af1aba4dbf9d72b47dc46 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 2.1E-23 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS01775 2bb2ba641a9af1aba4dbf9d72b47dc46 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.3E-27 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS01775 2bb2ba641a9af1aba4dbf9d72b47dc46 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 5.0E-27 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS01775 2bb2ba641a9af1aba4dbf9d72b47dc46 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 18.437 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 SUPERFAMILY SSF56176 349 429 1.15E-14 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 SMART SM01091 351 430 4.0E-16 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 Gene3D G3DSA:3.30.465.10 342 430 1.5E-18 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 Pfam PF01595 Domain of unknown function DUF21 7 201 1.3E-48 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 SUPERFAMILY SSF54631 204 338 1.17E-27 T 29-03-2018 CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 Pfam PF00571 CBS domain 286 334 3.0E-4 T 29-03-2018 IPR000644 CBS domain CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 Pfam PF00571 CBS domain 217 266 0.0024 T 29-03-2018 IPR000644 CBS domain CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 Pfam PF03471 Transporter associated domain 359 429 8.8E-15 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS17620 0f0cd2b8f69bb33e579d81e6998764a3 435 Gene3D G3DSA:3.10.580.10 195 341 1.9E-28 T 29-03-2018 CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 SUPERFAMILY SSF51735 98 284 2.79E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 Gene3D G3DSA:3.40.50.720 108 286 3.8E-55 T 29-03-2018 CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 316 1.1E-34 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 284 6.3E-59 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 SUPERFAMILY SSF52283 3 136 5.29E-34 T 29-03-2018 CSW12_RS06655 e881348a508af7da58a9a3cfa7596802 323 Gene3D G3DSA:3.40.50.720 1 107 1.2E-34 T 29-03-2018 CSW12_RS13945 d0ef33a90b86f9b9c160cd84ce121a16 446 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 438 4.7E-147 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 CSW12_RS13945 d0ef33a90b86f9b9c160cd84ce121a16 446 Pfam PF14620 YpeB sporulation 14 372 5.6E-138 T 29-03-2018 IPR014239 Spore germination YpeB GO:0009847 CSW12_RS09785 32559a3702273fe090e47e6d1b964b3c 197 Gene3D G3DSA:1.10.10.60 51 146 9.6E-11 T 29-03-2018 CSW12_RS09785 32559a3702273fe090e47e6d1b964b3c 197 Gene3D G3DSA:1.10.10.60 4 50 3.2E-16 T 29-03-2018 CSW12_RS09785 32559a3702273fe090e47e6d1b964b3c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS09785 32559a3702273fe090e47e6d1b964b3c 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS09785 32559a3702273fe090e47e6d1b964b3c 197 SUPERFAMILY SSF46689 5 84 2.0E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS09785 32559a3702273fe090e47e6d1b964b3c 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 9.0E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS20030 dc944d54789872f53e3b017c806471e3 320 Gene3D G3DSA:1.10.600.10 2 320 1.1E-87 T 29-03-2018 IPR008949 Isoprenoid synthase domain CSW12_RS20030 dc944d54789872f53e3b017c806471e3 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CSW12_RS20030 dc944d54789872f53e3b017c806471e3 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CSW12_RS20030 dc944d54789872f53e3b017c806471e3 320 SUPERFAMILY SSF48576 7 319 3.2E-84 T 29-03-2018 IPR008949 Isoprenoid synthase domain CSW12_RS20030 dc944d54789872f53e3b017c806471e3 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 4.2E-172 T 29-03-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CSW12_RS20030 dc944d54789872f53e3b017c806471e3 320 Pfam PF00348 Polyprenyl synthetase 31 268 8.5E-64 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 29-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 1.2E-35 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 1.2E-35 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 63 79 1.2E-35 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.2E-35 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 41 61 1.2E-35 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.2E-35 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 Gene3D G3DSA:3.40.190.80 148 267 1.7E-26 T 29-03-2018 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 Gene3D G3DSA:3.30.540.10 1 144 1.5E-40 T 29-03-2018 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 SUPERFAMILY SSF56655 5 263 2.75E-73 T 29-03-2018 CSW12_RS07955 cb51c4c909d73821684c55ce02a5ed97 267 Pfam PF00459 Inositol monophosphatase family 8 255 6.9E-61 T 29-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 Gene3D G3DSA:3.40.630.10 2 244 2.3E-41 T 29-03-2018 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 Gene3D G3DSA:3.40.630.10 248 391 1.2E-26 T 29-03-2018 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 Pfam PF07687 Peptidase dimerisation domain 186 281 8.6E-14 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 Pfam PF01546 Peptidase family M20/M25/M40 72 385 3.7E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 SUPERFAMILY SSF55031 184 295 1.03E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 375 2.5E-115 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 SUPERFAMILY SSF53187 11 197 3.43E-82 T 29-03-2018 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 SUPERFAMILY SSF53187 298 388 3.43E-82 T 29-03-2018 CSW12_RS02730 0aa9362d5a3b8584680d5da34d3e795c 391 PIRSF PIRSF005962 4 391 1.4E-134 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 328 539 9.7E-35 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 3.1E-16 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Gene3D G3DSA:3.10.20.30 2 65 3.9E-19 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 642 2.3E-239 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 SUPERFAMILY SSF55681 247 536 2.28E-95 T 29-03-2018 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 474 502 1.7E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 335 363 1.7E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 517 530 1.7E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 368 391 1.7E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 PRINTS PR01047 Threonyl-tRNA synthetase signature 544 556 1.7E-47 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 SMART SM00863 174 223 1.2E-25 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Gene3D G3DSA:3.30.980.10 70 231 1.7E-44 T 29-03-2018 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 645 35.271 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 SUPERFAMILY SSF55186 66 245 2.88E-64 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 SUPERFAMILY SSF52954 537 640 3.93E-32 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Pfam PF02824 TGS domain 5 64 5.3E-12 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 SUPERFAMILY SSF81271 5 64 5.89E-17 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Gene3D G3DSA:3.30.930.10 232 541 2.6E-105 T 29-03-2018 CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Pfam PF03129 Anticodon binding domain 551 640 2.9E-25 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS22495 4bd1c93c569c1c766d7101cfe29c1332 645 Gene3D G3DSA:3.40.50.800 542 644 8.8E-30 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS08655 b68d996f6ce6a17c030a278924b05ae3 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.238 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CSW12_RS08655 b68d996f6ce6a17c030a278924b05ae3 185 Pfam PF01765 Ribosome recycling factor 21 183 3.3E-65 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CSW12_RS08655 b68d996f6ce6a17c030a278924b05ae3 185 Gene3D G3DSA:1.10.132.20 75 184 9.5E-41 T 29-03-2018 CSW12_RS08655 b68d996f6ce6a17c030a278924b05ae3 185 Gene3D G3DSA:1.10.132.20 3 74 1.2E-8 T 29-03-2018 CSW12_RS08655 b68d996f6ce6a17c030a278924b05ae3 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.2E-77 T 29-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CSW12_RS08655 b68d996f6ce6a17c030a278924b05ae3 185 SUPERFAMILY SSF55194 5 184 2.35E-71 T 29-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CSW12_RS16785 73b97b1bf00a44600f97e7485e53d2da 119 Pfam PF13673 Acetyltransferase (GNAT) domain 11 117 9.5E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS16785 73b97b1bf00a44600f97e7485e53d2da 119 SUPERFAMILY SSF55729 7 115 1.74E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS16785 73b97b1bf00a44600f97e7485e53d2da 119 Gene3D G3DSA:3.40.630.30 25 117 1.9E-10 T 29-03-2018 CSW12_RS21730 8c4b0f27c0192c5fceaefad4c5acbfe0 350 SUPERFAMILY SSF111337 1 341 2.75E-141 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CSW12_RS21730 8c4b0f27c0192c5fceaefad4c5acbfe0 350 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.592 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CSW12_RS21730 8c4b0f27c0192c5fceaefad4c5acbfe0 350 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 3.2E-152 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CSW12_RS21730 8c4b0f27c0192c5fceaefad4c5acbfe0 350 Gene3D G3DSA:3.40.1780.10 1 133 8.4E-41 T 29-03-2018 CSW12_RS21730 8c4b0f27c0192c5fceaefad4c5acbfe0 350 Gene3D G3DSA:3.40.1780.10 172 342 1.0E-68 T 29-03-2018 CSW12_RS21730 8c4b0f27c0192c5fceaefad4c5acbfe0 350 Pfam PF02547 Queuosine biosynthesis protein 5 341 4.6E-144 T 29-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 SUPERFAMILY SSF55874 308 448 1.1E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 SUPERFAMILY SSF47384 227 304 2.75E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.6E-5 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 444 2.5E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 Gene3D G3DSA:3.30.565.10 287 455 7.2E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 Gene3D G3DSA:1.10.287.130 226 286 8.2E-11 T 29-03-2018 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 SMART SM00304 184 235 6.9E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 SUPERFAMILY SSF158472 185 232 1.28E-7 T 29-03-2018 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 Pfam PF00672 HAMP domain 186 232 6.8E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 SMART SM00387 349 457 9.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 303 1.3E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS13375 28fc8118b78a1bc359d72650733154e2 458 SMART SM00388 243 305 3.0E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 SUPERFAMILY SSF46785 1 70 2.04E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 SUPERFAMILY SSF55252 80 145 1.03E-18 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Gene3D G3DSA:3.30.1360.40 74 146 1.1E-23 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 147 8.2E-40 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Pfam PF02863 Arginine repressor, C-terminal domain 80 145 8.3E-22 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 7.0E-17 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 7.0E-17 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 7.0E-17 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 7.0E-17 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 53.441 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 68 4.5E-21 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 Gene3D G3DSA:1.10.10.10 3 66 6.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00695 367e6cbc64b25cd54b54af1bfc5a3b0d 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 127 3.0E-18 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 SUPERFAMILY SSF55890 324 368 1.7E-9 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 SMART SM00091 218 283 6.6E-4 T 29-03-2018 IPR000014 PAS domain CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Gene3D G3DSA:3.30.450.20 38 177 5.3E-19 T 29-03-2018 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 320 366 3.5E-9 T 29-03-2018 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Gene3D G3DSA:3.30.565.10 373 525 3.1E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Pfam PF17203 Single cache domain 3 40 170 1.1E-16 T 29-03-2018 IPR033463 Single cache domain 3 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Pfam PF13188 PAS domain 223 274 2.5E-4 T 29-03-2018 IPR000014 PAS domain CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 SUPERFAMILY SSF103190 42 172 7.85E-27 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 SUPERFAMILY SSF55785 218 309 8.55E-8 T 29-03-2018 IPR000014 PAS domain CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Gene3D G3DSA:1.10.287.130 314 372 1.2E-16 T 29-03-2018 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Gene3D G3DSA:3.30.450.20 221 313 7.4E-10 T 29-03-2018 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 4.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 4.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 484 4.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 470 4.4E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 SUPERFAMILY SSF55874 394 524 7.47E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 524 4.1E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03895 bb293580f98859e45777e66703db9da4 529 SMART SM00387 417 525 3.6E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16245 e36685214ce7ef1c37b3525f598e36f3 79 Gene3D G3DSA:2.40.240.20 1 75 2.0E-26 T 29-03-2018 CSW12_RS16245 e36685214ce7ef1c37b3525f598e36f3 79 Pfam PF10763 Protein of unknown function (DUF2584) 1 79 3.8E-27 T 29-03-2018 IPR019699 Protein of unknown function DUF2584 CSW12_RS16245 e36685214ce7ef1c37b3525f598e36f3 79 SUPERFAMILY SSF88697 1 79 1.04E-19 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 SUPERFAMILY SSF46785 4 95 1.34E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 Pfam PF12840 Helix-turn-helix domain 16 75 1.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 SMART SM00418 17 96 1.8E-25 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS31090 48a491c6f8f24731d36912898f3da271 96 Gene3D G3DSA:1.10.10.10 5 95 1.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 SUPERFAMILY SSF49478 626 694 1.49E-7 T 29-03-2018 CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 Gene3D G3DSA:2.60.40.10 429 522 7.0E-22 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 Gene3D G3DSA:2.60.40.10 523 624 1.2E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 713 743 7.6E-5 T 29-03-2018 CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 SUPERFAMILY SSF49478 438 506 1.41E-8 T 29-03-2018 CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 SUPERFAMILY SSF49478 532 600 1.18E-8 T 29-03-2018 CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 45 327 4.0E-24 T 29-03-2018 IPR026588 Choice-of-anchor A domain CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 Gene3D G3DSA:2.60.40.810 327 428 1.9E-22 T 29-03-2018 CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 Gene3D G3DSA:2.60.40.810 625 717 1.2E-21 T 29-03-2018 CSW12_RS14900 1972afa906f6769a365b0b669002aa09 745 SUPERFAMILY SSF49478 343 412 2.12E-7 T 29-03-2018 CSW12_RS08000 64b65f5fceaa749b311ff65ae0262baa 95 Pfam PF07408 Protein of unknown function (DUF1507) 9 91 1.3E-41 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 CSW12_RS08000 64b65f5fceaa749b311ff65ae0262baa 95 Gene3D G3DSA:1.10.287.750 8 90 1.6E-41 T 29-03-2018 CSW12_RS08000 64b65f5fceaa749b311ff65ae0262baa 95 Hamap MF_01560 UPF0358 protein . 3 93 27.755 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 CSW12_RS08000 64b65f5fceaa749b311ff65ae0262baa 95 SUPERFAMILY SSF140404 6 84 8.5E-37 T 29-03-2018 IPR009983 Uncharacterised protein family UPF0358 CSW12_RS05580 3a4923a7fb6de6f1c77a0b227ee1366e 281 Gene3D G3DSA:3.40.50.150 83 279 1.5E-11 T 29-03-2018 CSW12_RS05580 3a4923a7fb6de6f1c77a0b227ee1366e 281 SUPERFAMILY SSF53335 187 257 5.82E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS05580 3a4923a7fb6de6f1c77a0b227ee1366e 281 SUPERFAMILY SSF53335 82 150 5.82E-9 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS05580 3a4923a7fb6de6f1c77a0b227ee1366e 281 Pfam PF05711 Macrocin-O-methyltransferase (TylF) 8 280 3.5E-113 T 29-03-2018 IPR008884 Macrocin-O-methyltransferase CSW12_RS12995 ab5b9f292ea78108fa21c7ae26954050 233 SUPERFAMILY SSF81301 4 109 9.81E-11 T 29-03-2018 CSW12_RS12995 ab5b9f292ea78108fa21c7ae26954050 233 Pfam PF01909 Nucleotidyltransferase domain 23 43 2.4E-5 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CSW12_RS12995 ab5b9f292ea78108fa21c7ae26954050 233 Gene3D G3DSA:3.30.460.10 2 113 6.0E-16 T 29-03-2018 CSW12_RS06695 6d66333d7d0488152a5c4054a16f3e4a 203 SUPERFAMILY SSF52540 23 194 1.24E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS06695 6d66333d7d0488152a5c4054a16f3e4a 203 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 23 195 39.123 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CSW12_RS06695 6d66333d7d0488152a5c4054a16f3e4a 203 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 191 6.0E-88 T 29-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CSW12_RS06695 6d66333d7d0488152a5c4054a16f3e4a 203 Gene3D G3DSA:3.40.50.300 20 199 2.3E-54 T 29-03-2018 CSW12_RS06695 6d66333d7d0488152a5c4054a16f3e4a 203 Pfam PF01583 Adenylylsulphate kinase 25 177 6.8E-74 T 29-03-2018 CSW12_RS08615 db072189eb887caa646b36f5ff7e9138 434 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 337 360 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CSW12_RS08615 db072189eb887caa646b36f5ff7e9138 434 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 6 434 37.214 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CSW12_RS08615 db072189eb887caa646b36f5ff7e9138 434 SUPERFAMILY SSF51905 7 367 3.67E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS08615 db072189eb887caa646b36f5ff7e9138 434 Pfam PF01134 Glucose inhibited division protein A 6 368 1.8E-116 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CSW12_RS08615 db072189eb887caa646b36f5ff7e9138 434 Gene3D G3DSA:3.50.50.60 2 376 2.3E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS08615 db072189eb887caa646b36f5ff7e9138 434 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 5 431 1.6E-235 T 29-03-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 CSW12_RS21770 6c8a5884408a87d34baf773adc2aa42e 648 Gene3D G3DSA:3.10.350.10 2 52 6.3E-18 T 29-03-2018 CSW12_RS21770 6c8a5884408a87d34baf773adc2aa42e 648 SUPERFAMILY SSF54106 2 48 2.09E-11 T 29-03-2018 IPR018392 LysM domain CSW12_RS21770 6c8a5884408a87d34baf773adc2aa42e 648 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 1.5E-27 T 29-03-2018 IPR014248 Spore coat assembly protein SafA CSW12_RS21770 6c8a5884408a87d34baf773adc2aa42e 648 Pfam PF01476 LysM domain 4 48 2.1E-15 T 29-03-2018 IPR018392 LysM domain CSW12_RS21770 6c8a5884408a87d34baf773adc2aa42e 648 SMART SM00257 3 48 8.1E-17 T 29-03-2018 IPR018392 LysM domain CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 4.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 4.4E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 Gene3D G3DSA:1.10.1660.10 58 133 1.2E-5 T 29-03-2018 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 SMART SM00422 2 70 1.9E-19 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 Gene3D G3DSA:1.10.1660.10 1 57 1.7E-18 T 29-03-2018 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 Pfam PF13411 MerR HTH family regulatory protein 2 69 1.3E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS11100 36c91eec885fb277d935c922da74e81c 136 SUPERFAMILY SSF46955 2 109 2.27E-21 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS00710 4e6b6435a1b5d733e0cee8b5e44933e4 471 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 4 471 2.4E-188 T 29-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 CSW12_RS00710 4e6b6435a1b5d733e0cee8b5e44933e4 471 Pfam PF13520 Amino acid permease 7 443 2.1E-76 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS00710 4e6b6435a1b5d733e0cee8b5e44933e4 471 PIRSF PIRSF006060 1 470 1.5E-56 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS00710 4e6b6435a1b5d733e0cee8b5e44933e4 471 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 5 471 2.9E-222 T 29-03-2018 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 CSW12_RS16765 26eb4c5b7853a383ff76e331c520511f 291 Gene3D G3DSA:3.20.10.10 139 286 2.5E-44 T 29-03-2018 CSW12_RS16765 26eb4c5b7853a383ff76e331c520511f 291 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS16765 26eb4c5b7853a383ff76e331c520511f 291 SUPERFAMILY SSF56752 5 282 2.75E-79 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS16765 26eb4c5b7853a383ff76e331c520511f 291 Pfam PF01063 Amino-transferase class IV 37 259 6.8E-51 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS16765 26eb4c5b7853a383ff76e331c520511f 291 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 9 284 5.1E-94 T 29-03-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 CSW12_RS16765 26eb4c5b7853a383ff76e331c520511f 291 Gene3D G3DSA:3.30.470.10 2 138 1.5E-26 T 29-03-2018 CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 Pfam PF07702 UTRA domain 99 231 1.3E-21 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 SUPERFAMILY SSF46785 10 81 2.63E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 SUPERFAMILY SSF64288 65 239 4.08E-29 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 Gene3D G3DSA:3.40.1410.10 77 240 1.8E-24 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 6.4E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 SMART SM00345 18 77 4.5E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 Gene3D G3DSA:1.10.10.10 5 76 2.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23945 8ad9bd6eb94acf8444d0cc790fe4e463 241 SMART SM00866 98 234 2.0E-15 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 77 90 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 196 222 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 PIRSF PIRSF000770 2 237 1.7E-92 T 29-03-2018 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 Pfam PF04545 Sigma-70, region 4 172 222 2.9E-16 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 SUPERFAMILY SSF88659 138 223 2.24E-19 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 Gene3D G3DSA:1.10.1270.10 142 236 9.2E-22 T 29-03-2018 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 Gene3D G3DSA:1.10.601.10 19 119 2.2E-29 T 29-03-2018 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 SUPERFAMILY SSF88946 10 118 8.9E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 222 1.6E-30 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 Pfam PF04542 Sigma-70 region 2 53 120 1.9E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 211 222 7.6E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 77 90 7.6E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 196 211 7.6E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 PRINTS PR00046 Major sigma-70 factor signature 175 187 7.6E-14 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS21325 27dce26354d3e86b8e4f9c675754002d 237 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 3 226 1.1E-112 T 29-03-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS06125 dcbdbee89522b400e200d667d9eb3259 361 Pfam PF00561 alpha/beta hydrolase fold 71 338 8.2E-20 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS06125 dcbdbee89522b400e200d667d9eb3259 361 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 9 359 9.6E-137 T 29-03-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 CSW12_RS06125 dcbdbee89522b400e200d667d9eb3259 361 Gene3D G3DSA:3.40.50.1820 34 360 7.0E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS06125 dcbdbee89522b400e200d667d9eb3259 361 SUPERFAMILY SSF53474 56 357 3.27E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 Pfam PF11858 Domain of unknown function (DUF3378) 5 78 9.8E-27 T 29-03-2018 IPR024568 Ribonuclease HIII, N-terminal CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 SUPERFAMILY SSF53098 96 308 4.55E-53 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 PIRSF PIRSF037748 1 311 1.0E-122 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 Pfam PF01351 Ribonuclease HII 98 303 3.1E-48 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 Hamap MF_00053 Ribonuclease HIII [rnhC]. 2 310 37.119 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 Gene3D G3DSA:3.30.420.10 95 310 3.5E-46 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS22390 3004c82a21919a5fcb61fd06a5188d9b 311 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 6 302 6.6E-91 T 29-03-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 CSW12_RS01675 f38692c43e62ebd3373436bedc5eac9e 623 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 366 581 9.9E-28 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CSW12_RS01675 f38692c43e62ebd3373436bedc5eac9e 623 Gene3D G3DSA:3.20.20.190 353 596 4.4E-60 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS01675 f38692c43e62ebd3373436bedc5eac9e 623 SUPERFAMILY SSF51695 360 586 8.89E-64 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS01675 f38692c43e62ebd3373436bedc5eac9e 623 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 13 350 7.4E-83 T 29-03-2018 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 Gene3D G3DSA:2.60.40.740 279 411 9.9E-21 T 29-03-2018 CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 Gene3D G3DSA:2.60.40.810 29 170 4.7E-16 T 29-03-2018 CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 Gene3D G3DSA:2.60.40.810 412 527 1.8E-20 T 29-03-2018 CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 SUPERFAMILY SSF49478 183 246 7.06E-9 T 29-03-2018 CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 277 399 8.2E-23 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 SUPERFAMILY SSF49478 429 489 3.69E-6 T 29-03-2018 CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 529 559 1.6E-6 T 29-03-2018 CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 Gene3D G3DSA:2.60.40.10 171 278 5.1E-26 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS14910 46b777cd5bf356ae832fb12e012b2064 563 Pfam PF00746 LPXTG cell wall anchor motif 528 559 8.6E-6 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 PRINTS PR01607 Apyrase family signature 373 396 4.4E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 PRINTS PR01607 Apyrase family signature 7 25 4.4E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 PRINTS PR01607 Apyrase family signature 226 249 4.4E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 PRINTS PR01607 Apyrase family signature 463 482 4.4E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 PRINTS PR01607 Apyrase family signature 191 208 4.4E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 PRINTS PR01607 Apyrase family signature 253 273 4.4E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 SUPERFAMILY SSF56300 3 317 2.15E-83 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 Gene3D G3DSA:3.60.21.10 1 317 5.2E-72 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 Gene3D G3DSA:3.90.780.10 318 527 9.8E-48 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 SUPERFAMILY SSF55816 315 526 2.09E-50 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 Pfam PF00149 Calcineurin-like phosphoesterase 9 243 8.1E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 Pfam PF02872 5'-nucleotidase, C-terminal domain 320 489 3.8E-29 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS09310 5c9d046453452fc3683aa57afb46f697 527 ProSitePatterns PS00786 5'-nucleotidase signature 2. 91 102 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14675 efec0cba0eb57e09a17b5eeaff38a413 229 Pfam PF03070 TENA/THI-4/PQQC family 9 214 3.7E-56 T 29-03-2018 IPR004305 Thiaminase-2/PQQC CSW12_RS14675 efec0cba0eb57e09a17b5eeaff38a413 229 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 214 2.3E-74 T 29-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CSW12_RS14675 efec0cba0eb57e09a17b5eeaff38a413 229 Gene3D G3DSA:1.20.910.10 1 222 8.7E-59 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CSW12_RS14675 efec0cba0eb57e09a17b5eeaff38a413 229 SUPERFAMILY SSF48613 3 221 1.23E-71 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 SUPERFAMILY SSF55271 2 112 2.35E-42 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 SMART SM00534 600 787 1.8E-117 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 SMART SM00533 274 583 7.0E-99 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 SUPERFAMILY SSF48334 257 556 1.7E-86 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Pfam PF01624 MutS domain I 5 115 1.4E-46 T 29-03-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 SUPERFAMILY SSF52540 559 791 9.41E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Gene3D G3DSA:1.10.1420.10 253 398 3.5E-36 T 29-03-2018 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 807 0.0 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 SUPERFAMILY SSF53150 114 270 9.94E-29 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 681 697 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Pfam PF05188 MutS domain II 125 243 5.1E-7 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Pfam PF05192 MutS domain III 261 551 6.4E-44 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Gene3D G3DSA:3.40.1170.10 1 128 1.1E-47 T 29-03-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Gene3D G3DSA:1.10.1420.10 399 527 5.8E-30 T 29-03-2018 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Gene3D G3DSA:3.30.420.110 129 252 1.8E-15 T 29-03-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 PIRSF PIRSF037677 171 834 5.6E-128 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 PIRSF PIRSF037677 1 179 1.8E-29 T 29-03-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Pfam PF05190 MutS family domain IV 419 510 9.7E-27 T 29-03-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 879 25.537 T 29-03-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Gene3D G3DSA:3.40.50.300 559 792 1.9E-46 T 29-03-2018 CSW12_RS08935 fe28d4561e715d39234de97aee80b5bf 890 Pfam PF00488 MutS domain V 604 790 4.3E-84 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS21020 beac14d8a632f17b39e1a245e0bd91e8 256 Pfam PF00005 ABC transporter 20 168 3.2E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS21020 beac14d8a632f17b39e1a245e0bd91e8 256 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS21020 beac14d8a632f17b39e1a245e0bd91e8 256 SMART SM00382 29 214 6.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS21020 beac14d8a632f17b39e1a245e0bd91e8 256 Gene3D G3DSA:3.40.50.300 1 253 2.4E-61 T 29-03-2018 CSW12_RS21020 beac14d8a632f17b39e1a245e0bd91e8 256 SUPERFAMILY SSF52540 2 227 5.94E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04170 473015f988c5d8dce9d4fcea87abc034 183 Gene3D G3DSA:2.60.40.1240 66 183 8.8E-9 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS04170 473015f988c5d8dce9d4fcea87abc034 183 Pfam PF11611 Domain of unknown function (DUF4352) 81 164 7.5E-7 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 CSW12_RS14815 6b932fb5a2ba4c2fc2da9b36c5b3e814 147 Gene3D G3DSA:2.60.120.10 1 147 1.2E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS14815 6b932fb5a2ba4c2fc2da9b36c5b3e814 147 Pfam PF05995 Cysteine dioxygenase type I 47 146 1.9E-12 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CSW12_RS14815 6b932fb5a2ba4c2fc2da9b36c5b3e814 147 SUPERFAMILY SSF51182 3 146 4.46E-24 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 Pfam PF13537 Glutamine amidotransferase domain 48 169 4.2E-46 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 PIRSF PIRSF001589 1 606 2.1E-136 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 533 3.2E-156 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 SUPERFAMILY SSF52402 230 395 6.55E-68 T 29-03-2018 CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 SUPERFAMILY SSF52402 453 583 6.55E-68 T 29-03-2018 CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 Gene3D G3DSA:3.60.20.10 1 223 3.6E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 Gene3D G3DSA:3.40.50.620 224 606 2.5E-59 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 Pfam PF00733 Asparagine synthase 243 599 4.9E-91 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CSW12_RS19050 4dccc3750ffb1bbe476c18c307178ef9 607 SUPERFAMILY SSF56235 1 226 6.0E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS16805 c88b61c8d8e825b0c1eae3d29f4cb79e 326 Gene3D G3DSA:3.60.15.10 17 322 7.5E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16805 c88b61c8d8e825b0c1eae3d29f4cb79e 326 SUPERFAMILY SSF56281 57 278 6.22E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16805 c88b61c8d8e825b0c1eae3d29f4cb79e 326 PIRSF PIRSF038896 1 311 4.4E-92 T 29-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CSW12_RS16805 c88b61c8d8e825b0c1eae3d29f4cb79e 326 Pfam PF12706 Beta-lactamase superfamily domain 76 266 2.2E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12000 0cff568950304ffdf76d3bc85e8cf69e 280 SUPERFAMILY SSF88713 75 264 3.95E-50 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS12000 0cff568950304ffdf76d3bc85e8cf69e 280 Gene3D G3DSA:3.20.20.370 37 266 3.5E-46 T 29-03-2018 CSW12_RS12000 0cff568950304ffdf76d3bc85e8cf69e 280 Pfam PF01522 Polysaccharide deacetylase 74 184 4.1E-26 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS06860 7b5eb7bf0670435fee5b6f5fe7700ff7 206 Gene3D G3DSA:1.20.58.220 100 205 1.0E-8 T 29-03-2018 CSW12_RS06860 7b5eb7bf0670435fee5b6f5fe7700ff7 206 SUPERFAMILY SSF109755 7 197 3.84E-6 T 29-03-2018 CSW12_RS06860 7b5eb7bf0670435fee5b6f5fe7700ff7 206 Pfam PF01865 Protein of unknown function DUF47 5 203 3.5E-27 T 29-03-2018 IPR018445 Putative phosphate transport regulator CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 82 109 4.7E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 348 373 4.7E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 26 52 4.7E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 396 417 4.7E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 PRINTS PR00298 60kDa chaperonin signature 266 289 4.7E-73 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 42.809 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Gene3D G3DSA:3.50.7.10 184 371 1.6E-99 T 29-03-2018 IPR027409 GroEL-like apical domain CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Gene3D G3DSA:1.10.560.10 372 513 2.4E-27 T 29-03-2018 IPR027413 GroEL-like equatorial domain CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.3E-103 T 29-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 9.7E-259 T 29-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF54849 136 204 1.03E-25 T 29-03-2018 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 29-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF48592 404 518 2.37E-80 T 29-03-2018 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF48592 5 133 2.37E-80 T 29-03-2018 CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 Gene3D G3DSA:1.10.560.10 1 183 4.2E-35 T 29-03-2018 IPR027413 GroEL-like equatorial domain CSW12_RS28855 c9e652a9d8d8ef1e2c3e6687de8168a3 544 SUPERFAMILY SSF52029 183 374 7.92E-86 T 29-03-2018 IPR027409 GroEL-like apical domain CSW12_RS14640 3cb4882ac0cc0df0d97cc34c894255ca 255 Pfam PF13105 Protein of unknown function (DUF3959) 9 251 1.9E-141 T 29-03-2018 IPR025080 Protein of unknown function DUF3959 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 SUPERFAMILY SSF55424 323 443 5.5E-34 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 294 9.5E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 Gene3D G3DSA:3.50.50.60 1 104 8.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 3.1E-20 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 3.1E-20 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 3.1E-20 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 402 3.1E-20 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 3.1E-20 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 Gene3D G3DSA:3.50.50.60 105 244 2.8E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 SUPERFAMILY SSF51905 3 316 6.76E-46 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 Gene3D G3DSA:3.30.390.30 338 444 1.8E-25 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 Gene3D G3DSA:3.50.50.60 247 337 1.5E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 7.7E-28 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 7.7E-28 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 7.7E-28 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 7.7E-28 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 7.7E-28 T 29-03-2018 CSW12_RS05800 49130e870c602ff605d9fa634715cca8 444 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 430 1.1E-14 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 9.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 9.1E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 SMART SM00387 389 500 1.0E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 SUPERFAMILY SSF47384 259 343 6.08E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 390 488 2.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 Gene3D G3DSA:1.10.287.130 264 339 3.7E-16 T 29-03-2018 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 Gene3D G3DSA:3.30.565.10 347 501 1.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 SMART SM00304 216 268 4.5E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 341 2.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 SUPERFAMILY SSF55874 332 498 1.1E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 SMART SM00388 276 343 4.4E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS28875 23b74eefab4394a09de10439b5d45bcb 501 SUPERFAMILY SSF158472 221 266 2.22E-6 T 29-03-2018 CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 SUPERFAMILY SSF52540 670 917 3.9E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 SMART SM00490 780 863 2.3E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 Gene3D G3DSA:3.40.50.10810 425 722 6.0E-57 T 29-03-2018 CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 Pfam PF00271 Helicase conserved C-terminal domain 751 863 1.0E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 SMART SM00487 447 637 4.3E-31 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 Gene3D G3DSA:3.40.50.300 735 901 5.6E-39 T 29-03-2018 CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 SUPERFAMILY SSF52540 426 665 6.75E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 Pfam PF00176 SNF2 family N-terminal domain 470 735 1.8E-59 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CSW12_RS25990 88171c68ee298ce7ce9de280c6744dfb 918 Pfam PF12419 SNF2 Helicase protein 270 398 8.5E-34 T 29-03-2018 IPR022138 Helicase SWF/SNF-related CSW12_RS01810 d94d259c75542b8057d4724149dd3df3 396 SUPERFAMILY SSF53383 8 394 7.75E-108 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS01810 d94d259c75542b8057d4724149dd3df3 396 Gene3D G3DSA:3.40.640.10 52 288 2.6E-53 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS01810 d94d259c75542b8057d4724149dd3df3 396 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 241 250 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CSW12_RS01810 d94d259c75542b8057d4724149dd3df3 396 Gene3D G3DSA:3.90.1150.10 289 394 7.7E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS01810 d94d259c75542b8057d4724149dd3df3 396 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 396 2.0E-191 T 29-03-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CSW12_RS01810 d94d259c75542b8057d4724149dd3df3 396 Pfam PF00155 Aminotransferase class I and II 43 383 5.9E-62 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 SUPERFAMILY SSF55874 207 355 1.81E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 SUPERFAMILY SSF158472 83 127 1.44E-6 T 29-03-2018 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 137 200 1.4E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 251 346 2.0E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 Gene3D G3DSA:3.30.565.10 207 358 5.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 SMART SM00388 136 203 8.6E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 Gene3D G3DSA:1.10.287.130 119 199 3.1E-19 T 29-03-2018 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 SMART SM00387 249 357 3.3E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 SUPERFAMILY SSF47384 120 200 2.16E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 338 2.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11745 72b78a516158c10c8a2019548c996cb7 358 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 314 2.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS20545 0faccc829ae27dccef93d93c60c4d23a 67 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 2.0E-14 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CSW12_RS20545 0faccc829ae27dccef93d93c60c4d23a 67 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 1.8E-29 T 29-03-2018 IPR009570 Stage III sporulation protein AC CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 Gene3D G3DSA:3.40.630.10 172 491 2.0E-129 T 29-03-2018 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 SUPERFAMILY SSF52949 11 175 5.36E-32 T 29-03-2018 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 15 143 4.7E-28 T 29-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 179 484 2.8E-117 T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 SUPERFAMILY SSF53187 175 489 3.45E-114 T 29-03-2018 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 340 347 - T 29-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 Gene3D G3DSA:3.40.220.10 11 171 8.1E-27 T 29-03-2018 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 PRINTS PR00481 Cytosol aminopeptidase signature 314 335 1.9E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 PRINTS PR00481 Cytosol aminopeptidase signature 336 356 1.9E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 PRINTS PR00481 Cytosol aminopeptidase signature 277 298 1.9E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 PRINTS PR00481 Cytosol aminopeptidase signature 364 379 1.9E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 PRINTS PR00481 Cytosol aminopeptidase signature 255 272 1.9E-50 T 29-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CSW12_RS24395 24e3c84f17fdf8f6efbff312cf8a5ed6 494 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 2 493 35.133 T 29-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CSW12_RS14350 7728322d2c52f8326791837861139a59 267 Pfam PF13673 Acetyltransferase (GNAT) domain 150 258 8.5E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS14350 7728322d2c52f8326791837861139a59 267 Gene3D G3DSA:3.40.630.30 65 263 8.0E-12 T 29-03-2018 CSW12_RS14350 7728322d2c52f8326791837861139a59 267 SUPERFAMILY SSF55729 133 259 9.12E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 SUPERFAMILY SSF48600 5 88 1.68E-21 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 Pfam PF01817 Chorismate mutase type II 10 87 1.3E-18 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 Gene3D G3DSA:1.20.59.10 1 97 1.6E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 Pfam PF00793 DAHP synthetase I family 110 351 1.2E-81 T 29-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 SUPERFAMILY SSF51569 58 352 7.05E-102 T 29-03-2018 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 SMART SM00830 10 89 3.3E-24 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 351 1.2E-122 T 29-03-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 101 2.2E-43 T 29-03-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS12900 250acfbef897c7165ccbe6d3427224ef 358 Gene3D G3DSA:3.20.20.70 98 357 9.5E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS21345 f5485016ac08d56a766572da659aa879 207 SUPERFAMILY SSF55469 2 204 8.9E-51 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS21345 f5485016ac08d56a766572da659aa879 207 Gene3D G3DSA:3.40.109.10 1 205 1.6E-41 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS21345 f5485016ac08d56a766572da659aa879 207 Pfam PF00881 Nitroreductase family 9 183 2.8E-22 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 505 641 1.3E-30 T 29-03-2018 IPR002178 PTS EIIA type-2 domain CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 SUPERFAMILY SSF63520 299 400 5.1E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Gene3D G3DSA:3.40.930.10 500 642 6.2E-31 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 SUPERFAMILY SSF55804 504 642 3.4E-31 T 29-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Gene3D G3DSA:3.40.50.2300 406 498 1.6E-16 T 29-03-2018 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Pfam PF05043 Mga helix-turn-helix domain 86 166 2.8E-11 T 29-03-2018 IPR007737 Mga helix-turn-helix domain CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Pfam PF08279 HTH domain 4 61 5.6E-12 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 SUPERFAMILY SSF52794 408 494 1.05E-6 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Gene3D G3DSA:1.10.1790.10 173 284 6.0E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Gene3D G3DSA:1.10.1790.10 285 402 3.3E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Pfam PF00874 PRD domain 204 283 6.8E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Pfam PF00874 PRD domain 310 398 9.3E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Gene3D G3DSA:1.10.10.10 2 67 3.7E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 Gene3D G3DSA:1.10.10.10 87 153 4.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03290 6944b6507455bcd495d1f0293a346d16 643 SUPERFAMILY SSF63520 186 283 8.5E-16 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS30710 062b09f41bac303ae8500b4d5042c09c 345 Gene3D G3DSA:2.40.10.10 237 338 1.4E-15 T 29-03-2018 CSW12_RS30710 062b09f41bac303ae8500b4d5042c09c 345 SUPERFAMILY SSF50494 152 322 9.16E-15 T 29-03-2018 IPR009003 Peptidase S1, PA clan CSW12_RS22355 e38c3b5e585485314e526869acd1d20f 441 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 418 1.2E-136 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS22355 e38c3b5e585485314e526869acd1d20f 441 Pfam PF05525 Branched-chain amino acid transport protein 9 432 4.3E-143 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF81301 185 398 4.41E-67 T 29-03-2018 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:3.10.20.30 388 461 9.3E-24 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 SMART SM00954 240 350 4.5E-69 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF13291 ACT domain 649 724 1.4E-20 T 29-03-2018 IPR002912 ACT domain CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:3.30.70.260 647 727 3.2E-10 T 29-03-2018 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF81271 381 453 8.01E-23 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF109604 10 196 2.86E-77 T 29-03-2018 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF02824 TGS domain 394 453 1.8E-21 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 1.3E-39 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Pfam PF13328 HD domain 31 180 1.0E-52 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 SUPERFAMILY SSF55021 648 726 9.67E-11 T 29-03-2018 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 724 3.2E-260 T 29-03-2018 IPR004811 RelA/SpoT family GO:0015969 CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 SMART SM00471 46 158 1.3E-8 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS21675 6f7d0dc9f0987fe35189880e8790c325 727 Gene3D G3DSA:3.30.460.10 193 330 7.6E-46 T 29-03-2018 CSW12_RS12540 01c127b0da20fd8ddcde7fe522c312de 212 SUPERFAMILY SSF55469 9 210 1.96E-60 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS12540 01c127b0da20fd8ddcde7fe522c312de 212 Pfam PF00881 Nitroreductase family 15 192 4.6E-33 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS12540 01c127b0da20fd8ddcde7fe522c312de 212 Gene3D G3DSA:3.40.109.10 1 212 9.5E-54 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 SUPERFAMILY SSF55190 7 105 2.49E-23 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Gene3D G3DSA:1.10.730.10 431 562 3.3E-44 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 SMART SM01016 5 84 5.1E-21 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 5.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 129 145 5.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 153 166 5.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 PRINTS PR01038 Arginyl-tRNA synthetase signature 114 129 5.4E-20 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 562 25.585 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 SUPERFAMILY SSF52374 112 444 1.16E-97 T 29-03-2018 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Gene3D G3DSA:3.30.1360.70 1 105 4.5E-26 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 6 562 6.6E-154 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Pfam PF00750 tRNA synthetases class I (R) 95 435 3.2E-99 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Gene3D G3DSA:3.40.50.620 107 430 2.6E-58 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Pfam PF05746 DALR anticodon binding domain 450 562 4.9E-32 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 SUPERFAMILY SSF47323 444 562 5.89E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 84 3.6E-15 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS17085 263bc30a6ba709fdb2c296b08a846881 562 SMART SM00836 450 562 1.4E-40 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Gene3D G3DSA:2.60.40.1710 693 811 7.8E-9 T 29-03-2018 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 PIRSF PIRSF037844 1 1407 0.0 T 29-03-2018 IPR017292 Peptidase S8A, Vpr CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Pfam PF02225 PA domain 461 537 4.3E-17 T 29-03-2018 IPR003137 PA domain CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 235 6.3E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 293 306 6.3E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 PRINTS PR00723 Subtilisin serine protease family (S8) signature 614 630 6.3E-20 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Gene3D G3DSA:2.60.40.680 1076 1218 6.5E-12 T 29-03-2018 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 SUPERFAMILY SSF52025 457 550 1.31E-16 T 29-03-2018 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Gene3D G3DSA:2.60.40.1310 908 1075 2.9E-4 T 29-03-2018 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Pfam PF05922 Peptidase inhibitor I9 87 183 5.7E-8 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 297 307 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 221 232 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Gene3D G3DSA:3.30.70.80 70 181 1.7E-7 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 615 625 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Pfam PF00082 Subtilase family 216 665 2.0E-66 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Pfam PF06280 Fn3-like domain 736 809 3.4E-6 T 29-03-2018 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 SUPERFAMILY SSF63446 1320 1375 5.62E-7 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 SUPERFAMILY SSF52743 564 675 6.94E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 SUPERFAMILY SSF52743 200 422 6.94E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS24105 7e6b0b79fe062d944522eecdb3fd58bf 1407 Gene3D G3DSA:3.40.50.200 182 682 2.2E-94 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS20830 78e832a195deb326a27c86e4db5c117e 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 73 3.5E-38 T 29-03-2018 IPR020254 Protein of unknown function DUF2626 CSW12_RS20830 78e832a195deb326a27c86e4db5c117e 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 80 1.0E-38 T 29-03-2018 IPR020254 Protein of unknown function DUF2626 CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.10.350.10 3 48 8.5E-11 T 29-03-2018 CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF51445 130 324 2.58E-46 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF51445 384 427 2.58E-46 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF54106 54 97 3.79E-10 T 29-03-2018 IPR018392 LysM domain CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Pfam PF01476 LysM domain 54 97 6.2E-10 T 29-03-2018 IPR018392 LysM domain CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Pfam PF01476 LysM domain 5 47 5.5E-9 T 29-03-2018 IPR018392 LysM domain CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Pfam PF00704 Glycosyl hydrolases family 18 176 410 8.7E-24 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.10.50.10 341 383 6.2E-18 T 29-03-2018 IPR029070 Chitinase insertion domain CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SMART SM00636 104 412 7.6E-28 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SUPERFAMILY SSF54106 4 48 9.55E-8 T 29-03-2018 IPR018392 LysM domain CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.20.20.80 106 340 7.7E-35 T 29-03-2018 CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 Gene3D G3DSA:3.10.350.10 49 102 6.8E-13 T 29-03-2018 CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SMART SM00257 4 48 2.1E-8 T 29-03-2018 IPR018392 LysM domain CSW12_RS09710 4772d2e8d59d08abb3a51b109b7d1ddc 430 SMART SM00257 53 97 1.4E-10 T 29-03-2018 IPR018392 LysM domain CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF03144 Elongation factor Tu domain 2 224 294 3.3E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.40.50.300 71 198 1.4E-30 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 54 62 2.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 10 23 2.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.6E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.30.70.240 406 486 8.6E-20 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.40.50.300 2 70 1.8E-10 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 SMART SM00838 400 488 9.8E-5 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:3.30.70.870 308 405 3.1E-32 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF14492 Elongation Factor G, domain II 333 382 3.8E-7 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 604 4.6E-290 T 29-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF50447 155 304 1.35E-31 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF00679 Elongation factor G C-terminus 402 482 2.5E-25 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF54980 403 518 3.36E-29 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 155 1.3E-22 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:2.40.30.10 199 307 2.6E-21 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF54980 307 392 4.32E-15 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 3.4E-57 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 Gene3D G3DSA:2.40.50.250 488 578 1.5E-36 T 29-03-2018 CSW12_RS07965 940b845aa94eae1e0abf41a9788fab04 614 SUPERFAMILY SSF52540 3 211 3.56E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS15020 25fda3dfe2105ff17cbd3a70ad15bcdb 303 Pfam PF00682 HMGL-like 9 280 6.9E-47 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CSW12_RS15020 25fda3dfe2105ff17cbd3a70ad15bcdb 303 SUPERFAMILY SSF51569 4 293 4.58E-68 T 29-03-2018 CSW12_RS15020 25fda3dfe2105ff17cbd3a70ad15bcdb 303 Gene3D G3DSA:3.20.20.70 2 299 1.2E-94 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS14845 81ca7d9747986590d1c7126ba06ee6b0 364 Gene3D G3DSA:1.10.10.60 56 108 2.3E-8 T 29-03-2018 CSW12_RS14845 81ca7d9747986590d1c7126ba06ee6b0 364 SUPERFAMILY SSF46689 56 104 4.3E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS14845 81ca7d9747986590d1c7126ba06ee6b0 364 SMART SM00342 19 101 8.9E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS14845 81ca7d9747986590d1c7126ba06ee6b0 364 Gene3D G3DSA:1.10.10.60 1 55 2.1E-11 T 29-03-2018 CSW12_RS14845 81ca7d9747986590d1c7126ba06ee6b0 364 SUPERFAMILY SSF46689 2 52 1.16E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS14845 81ca7d9747986590d1c7126ba06ee6b0 364 Pfam PF12833 Helix-turn-helix domain 25 101 7.3E-16 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS02000 bd0b53aec3425ae82ad0c227e697824a 308 Pfam PF00005 ABC transporter 31 181 5.5E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS02000 bd0b53aec3425ae82ad0c227e697824a 308 SMART SM00382 39 238 1.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS02000 bd0b53aec3425ae82ad0c227e697824a 308 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS02000 bd0b53aec3425ae82ad0c227e697824a 308 SUPERFAMILY SSF52540 3 253 5.21E-76 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02000 bd0b53aec3425ae82ad0c227e697824a 308 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 276 1.1E-7 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS02000 bd0b53aec3425ae82ad0c227e697824a 308 Gene3D G3DSA:3.40.50.300 1 301 1.0E-78 T 29-03-2018 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 SUPERFAMILY SSF143800 1 80 7.06E-24 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 27.75 T 29-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 9.8E-20 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 Pfam PF01197 Ribosomal protein L31 1 79 1.2E-28 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 PRINTS PR01249 Ribosomal protein L31 signature 45 60 2.6E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.6E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS26445 534bb178ebbf231ad42537171e69a916 81 PRINTS PR01249 Ribosomal protein L31 signature 60 78 2.6E-19 T 29-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 SUPERFAMILY SSF88697 277 366 7.73E-20 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 Pfam PF01472 PUA domain 277 347 6.2E-21 T 29-03-2018 IPR002478 PUA domain GO:0003723 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 29-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 Gene3D G3DSA:3.40.1160.10 1 264 5.3E-55 T 29-03-2018 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 365 4.3E-136 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 260 36.104 T 29-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 1.8E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 1.8E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 1.8E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 1.8E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 1.8E-51 T 29-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 PIRSF PIRSF000729 1 367 2.0E-147 T 29-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 Gene3D G3DSA:2.30.130.10 276 366 9.7E-25 T 29-03-2018 IPR002478 PUA domain GO:0003723 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 SUPERFAMILY SSF53633 4 254 1.7E-64 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 SMART SM00359 277 359 1.9E-15 T 29-03-2018 IPR002478 PUA domain GO:0003723 CSW12_RS12745 685582bb034cdf60bd680a8a6f5d4f7c 367 Pfam PF00696 Amino acid kinase family 4 232 1.1E-42 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS03125 027f00010664cc5d3d741a714de512d9 212 Gene3D G3DSA:1.10.533.10 69 143 2.6E-4 T 29-03-2018 CSW12_RS03125 027f00010664cc5d3d741a714de512d9 212 Gene3D G3DSA:1.10.10.10 180 210 0.023 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03125 027f00010664cc5d3d741a714de512d9 212 Gene3D G3DSA:1.10.10.60 144 179 0.011 T 29-03-2018 CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 SUPERFAMILY SSF46689 3 64 8.25E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 SUPERFAMILY SSF48498 81 188 2.45E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 Gene3D G3DSA:1.10.10.60 8 56 8.0E-14 T 29-03-2018 CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.8E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 Gene3D G3DSA:1.10.357.10 57 191 6.0E-13 T 29-03-2018 CSW12_RS18525 d8df7f20c44c516e0098373911ae1a8d 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 2.3E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS16240 03add432c636914d061494de5d065ecc 385 SUPERFAMILY SSF56300 1 318 9.12E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS16240 03add432c636914d061494de5d065ecc 385 Pfam PF00149 Calcineurin-like phosphoesterase 1 182 6.1E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS16240 03add432c636914d061494de5d065ecc 385 Gene3D G3DSA:3.60.21.10 1 72 4.2E-14 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS16240 03add432c636914d061494de5d065ecc 385 Gene3D G3DSA:3.60.21.10 73 273 1.4E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS16240 03add432c636914d061494de5d065ecc 385 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 249 6.2E-46 T 29-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CSW12_RS16240 03add432c636914d061494de5d065ecc 385 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 272 357 4.2E-9 T 29-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CSW12_RS09120 250d05a8d6852daa4cbda20c0ea7d0b3 272 Gene3D G3DSA:3.40.50.1820 14 272 1.8E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS09120 250d05a8d6852daa4cbda20c0ea7d0b3 272 Pfam PF00756 Putative esterase 26 221 1.5E-21 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CSW12_RS09120 250d05a8d6852daa4cbda20c0ea7d0b3 272 SUPERFAMILY SSF53474 5 269 1.74E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 186 1.7E-29 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 2.0E-29 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 SUPERFAMILY SSF53901 3 324 2.64E-59 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 Gene3D G3DSA:3.40.47.10 1 163 9.1E-33 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 324 2.0E-109 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 324 63.588 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS18710 b58bd2593d117be089e3821a9c867c86 327 Gene3D G3DSA:3.40.47.10 164 323 6.2E-34 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS19925 b2790d6e21d90d2650779b0a6eb7d840 234 Gene3D G3DSA:3.40.50.10320 1 234 9.5E-58 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CSW12_RS19925 b2790d6e21d90d2650779b0a6eb7d840 234 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 124 1.2E-23 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CSW12_RS19925 b2790d6e21d90d2650779b0a6eb7d840 234 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 224 4.6E-99 T 29-03-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 CSW12_RS19925 b2790d6e21d90d2650779b0a6eb7d840 234 SUPERFAMILY SSF102588 4 226 1.96E-59 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CSW12_RS26185 6b45c1596b42109aca9884124dc3219d 282 Pfam PF01551 Peptidase family M23 113 211 8.4E-23 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS26185 6b45c1596b42109aca9884124dc3219d 282 SUPERFAMILY SSF51261 105 215 3.61E-27 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS26185 6b45c1596b42109aca9884124dc3219d 282 Gene3D G3DSA:2.70.70.10 68 282 1.8E-29 T 29-03-2018 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.8E-83 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 SUPERFAMILY SSF52283 305 360 2.13E-67 T 29-03-2018 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 SUPERFAMILY SSF52283 1 136 2.13E-67 T 29-03-2018 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 Gene3D G3DSA:3.40.50.720 187 371 8.7E-46 T 29-03-2018 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 Gene3D G3DSA:3.40.50.720 1 186 4.1E-44 T 29-03-2018 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 SMART SM01003 4 136 1.2E-77 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.5E-180 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 SMART SM01002 148 297 4.2E-90 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 6.3E-47 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 SUPERFAMILY SSF51735 136 303 2.05E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01680 ed3d3d437e66009179599d14a8843c57 377 PIRSF PIRSF000183 1 371 3.6E-192 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Pfam PF00476 DNA polymerase family A 513 889 2.5E-161 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SUPERFAMILY SSF47807 185 300 3.29E-34 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SMART SM00279 187 222 5.0E-17 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Gene3D G3DSA:1.20.1060.10 506 618 3.9E-34 T 29-03-2018 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Gene3D G3DSA:3.40.50.1010 17 198 4.8E-69 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 ProSitePatterns PS00447 DNA polymerase family A signature. 717 736 - T 29-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Gene3D G3DSA:3.30.420.10 323 505 5.9E-24 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SMART SM00475 17 276 1.5E-151 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SMART SM00482 648 855 1.7E-119 T 29-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SMART SM00474 315 481 3.5E-12 T 29-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 186 279 2.7E-36 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Gene3D G3DSA:1.10.150.20 199 277 2.6E-32 T 29-03-2018 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Gene3D G3DSA:3.30.70.370 619 706 5.2E-17 T 29-03-2018 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Gene3D G3DSA:3.30.70.370 717 891 1.3E-55 T 29-03-2018 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 18 183 2.3E-54 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SUPERFAMILY SSF53098 315 482 6.68E-45 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 717 742 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 640 655 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 693 706 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 808 824 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 787 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 617 639 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 838 851 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 663 686 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 PRINTS PR00868 DNA-polymerase family A (pol I) signature 754 765 6.0E-82 T 29-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SUPERFAMILY SSF88723 16 183 2.01E-56 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 SUPERFAMILY SSF56672 485 891 1.22E-159 T 29-03-2018 CSW12_RS22555 63abfbd2285cd0e43d193e911493df47 891 TIGRFAM TIGR00593 pola: DNA polymerase I 19 891 0.0 T 29-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS11005 531832695fd091512009ceab13fb5373 163 Gene3D G3DSA:3.40.50.720 1 163 1.1E-39 T 29-03-2018 CSW12_RS11005 531832695fd091512009ceab13fb5373 163 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 150 163 9.3E-5 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11005 531832695fd091512009ceab13fb5373 163 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 126 139 9.3E-5 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11005 531832695fd091512009ceab13fb5373 163 SUPERFAMILY SSF51735 1 163 4.92E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11005 531832695fd091512009ceab13fb5373 163 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 1 163 1.0E-38 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 SUPERFAMILY SSF46785 3 82 9.25E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 Gene3D G3DSA:1.10.10.10 1 77 4.9E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 4.5E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 4.5E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 4.5E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 SMART SM00418 3 81 3.7E-30 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23890 36d4bc6e8bcbb71f6b39351682632644 90 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 3.7E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Gene3D G3DSA:3.40.50.980 2 154 1.4E-35 T 29-03-2018 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 492 1.6E-8 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Gene3D G3DSA:3.30.300.30 398 504 8.0E-29 T 29-03-2018 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Gene3D G3DSA:2.30.38.10 310 397 1.5E-17 T 29-03-2018 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Gene3D G3DSA:3.40.50.980 155 309 5.3E-35 T 29-03-2018 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 504 245.487 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 428 2.7E-106 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 Pfam PF00501 AMP-binding enzyme 8 404 9.0E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 503 2.1E-215 T 29-03-2018 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13 CSW12_RS06410 d0202212eedd9607c78e47951ee7c789 504 SUPERFAMILY SSF56801 4 501 1.7E-126 T 29-03-2018 CSW12_RS27305 497e9c4a1564a7769e7dd6a69b2e8e50 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 8.4E-22 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27305 497e9c4a1564a7769e7dd6a69b2e8e50 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 29-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27305 497e9c4a1564a7769e7dd6a69b2e8e50 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.359 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27305 497e9c4a1564a7769e7dd6a69b2e8e50 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 3.0E-16 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27305 497e9c4a1564a7769e7dd6a69b2e8e50 44 Pfam PF00468 Ribosomal protein L34 1 44 2.8E-24 T 29-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 Pfam PF00464 Serine hydroxymethyltransferase 5 381 2.5E-180 T 29-03-2018 CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 Gene3D G3DSA:3.40.640.10 34 270 2.6E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 SUPERFAMILY SSF53383 3 412 3.85E-184 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 PIRSF PIRSF000412 2 414 6.4E-172 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 4 412 54.077 T 29-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 Gene3D G3DSA:3.90.1150.10 271 411 2.3E-61 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS26360 13629198758d8e0fab49852ea8d6ec6c 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 219 235 - T 29-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CSW12_RS22675 c7c340f7b869c64976858e584c457369 87 Pfam PF13133 Protein of unknown function (DUF3949) 19 79 3.4E-32 T 29-03-2018 IPR025032 Protein of unknown function DUF3949 CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 3.5E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.8E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.8E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 SUPERFAMILY SSF46785 4 86 5.55E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 SMART SM00345 12 71 5.1E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 Gene3D G3DSA:1.10.10.10 6 208 1.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22640 04efec92dfd0f306625713e19f05e28c 214 SUPERFAMILY SSF48008 93 209 6.02E-5 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CSW12_RS09560 ea1878160895abf2970ee627161502e9 269 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 4 204 4.3E-62 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS09560 ea1878160895abf2970ee627161502e9 269 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 210 264 1.3E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS09560 ea1878160895abf2970ee627161502e9 269 PIRSF PIRSF006483 1 269 4.9E-87 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS01510 4ec493059e3f17bd5cec43f72f37f121 230 SMART SM00448 5 118 1.5E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01510 4ec493059e3f17bd5cec43f72f37f121 230 SUPERFAMILY SSF52172 5 158 5.55E-34 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS01510 4ec493059e3f17bd5cec43f72f37f121 230 Gene3D G3DSA:1.10.10.10 137 230 5.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01510 4ec493059e3f17bd5cec43f72f37f121 230 Gene3D G3DSA:3.40.50.2300 4 136 2.6E-29 T 29-03-2018 CSW12_RS01510 4ec493059e3f17bd5cec43f72f37f121 230 PIRSF PIRSF006171 3 230 4.7E-83 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CSW12_RS01510 4ec493059e3f17bd5cec43f72f37f121 230 Pfam PF00072 Response regulator receiver domain 7 117 2.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS19955 937e795d6069ec84bd55af43724dfe87 213 SMART SM00987 25 204 3.4E-21 T 29-03-2018 CSW12_RS19955 937e795d6069ec84bd55af43724dfe87 213 SMART SM00986 25 204 3.4E-21 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS19955 937e795d6069ec84bd55af43724dfe87 213 Pfam PF03167 Uracil DNA glycosylase superfamily 26 203 6.6E-41 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS19955 937e795d6069ec84bd55af43724dfe87 213 SUPERFAMILY SSF52141 14 209 1.64E-40 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS19955 937e795d6069ec84bd55af43724dfe87 213 Gene3D G3DSA:3.40.470.10 8 212 1.0E-38 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS21290 7e0a231517ffa8b5d50160c9d8c64dec 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 6.2E-56 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CSW12_RS21290 7e0a231517ffa8b5d50160c9d8c64dec 189 Pfam PF01467 Cytidylyltransferase-like 6 162 1.5E-31 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CSW12_RS21290 7e0a231517ffa8b5d50160c9d8c64dec 189 Gene3D G3DSA:3.40.50.620 1 189 1.2E-49 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS21290 7e0a231517ffa8b5d50160c9d8c64dec 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 3.7E-11 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CSW12_RS21290 7e0a231517ffa8b5d50160c9d8c64dec 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 30.899 T 29-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CSW12_RS21290 7e0a231517ffa8b5d50160c9d8c64dec 189 SUPERFAMILY SSF52374 3 187 4.38E-50 T 29-03-2018 CSW12_RS30895 169d46a6484b7d20b19fbb7808c67e49 82 Pfam PF17362 Family of unknown function 5 82 3.6E-22 T 29-03-2018 CSW12_RS18940 c323401269fe742e9d3a0b424a1bbdee 232 SUPERFAMILY SSF52317 1 204 4.76E-31 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS18940 c323401269fe742e9d3a0b424a1bbdee 232 Pfam PF03575 Peptidase family S51 3 203 2.7E-60 T 29-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CSW12_RS18940 c323401269fe742e9d3a0b424a1bbdee 232 Gene3D G3DSA:3.40.50.880 1 230 4.4E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 SMART SM00388 258 324 1.1E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 SMART SM00387 369 482 3.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 SUPERFAMILY SSF158472 184 233 1.02E-9 T 29-03-2018 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 Pfam PF00672 HAMP domain 184 233 7.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 SMART SM00304 184 236 1.7E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 480 6.6E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 323 8.0E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 Gene3D G3DSA:1.10.287.130 237 305 4.8E-11 T 29-03-2018 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 SUPERFAMILY SSF55874 314 481 3.27E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 2.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 436 2.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 422 2.5E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 Gene3D G3DSA:3.30.565.10 306 481 5.4E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14085 f24585d303bfdc7d08c56ae00ca5e854 490 SUPERFAMILY SSF47384 244 324 8.63E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS20130 c7a6044fcdfcdc9d828e67175d70f421 246 Gene3D G3DSA:3.40.50.1820 5 234 9.2E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS20130 c7a6044fcdfcdc9d828e67175d70f421 246 SUPERFAMILY SSF53474 6 232 3.92E-31 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS20130 c7a6044fcdfcdc9d828e67175d70f421 246 Pfam PF12146 Serine aminopeptidase, S33 42 215 8.6E-11 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 Pfam PF13538 UvrD-like helicase C-terminal domain 630 677 1.8E-10 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 Pfam PF13361 UvrD-like helicase C-terminal domain 524 619 8.0E-7 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 SUPERFAMILY SSF52540 175 313 3.38E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 SUPERFAMILY SSF52540 416 682 3.38E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 Gene3D G3DSA:3.40.50.300 525 691 1.5E-30 T 29-03-2018 CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 Pfam PF13245 AAA domain 186 503 4.2E-10 T 29-03-2018 CSW12_RS13625 5658db8a8aae09f252bd443166b978e4 691 Gene3D G3DSA:3.40.50.300 180 524 1.3E-34 T 29-03-2018 CSW12_RS08835 b1c45f2fcd0db5bdf11204e456749945 319 Gene3D G3DSA:1.10.3470.10 1 307 2.3E-48 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS08835 b1c45f2fcd0db5bdf11204e456749945 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 288 1.6E-40 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS30315 947cb46c39f84cf0fa6f160b7de754b5 110 SUPERFAMILY SSF53041 1 74 1.7E-19 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30315 947cb46c39f84cf0fa6f160b7de754b5 110 Gene3D G3DSA:3.40.50.1390 1 44 1.1E-13 T 29-03-2018 CSW12_RS30315 947cb46c39f84cf0fa6f160b7de754b5 110 Pfam PF00239 Resolvase, N terminal domain 1 74 2.6E-19 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30315 947cb46c39f84cf0fa6f160b7de754b5 110 Gene3D G3DSA:1.20.5.40 45 72 2.8E-12 T 29-03-2018 CSW12_RS19535 bc75f9db33f90ae6a977cddd1c9de502 518 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 418 438 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CSW12_RS19535 bc75f9db33f90ae6a977cddd1c9de502 518 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 436 5.2E-92 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS19535 bc75f9db33f90ae6a977cddd1c9de502 518 Pfam PF00474 Sodium:solute symporter family 35 436 3.4E-125 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS19535 bc75f9db33f90ae6a977cddd1c9de502 518 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 150 175 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 7.7E-12 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 Pfam PF00155 Aminotransferase class I and II 81 438 6.3E-22 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 SUPERFAMILY SSF46785 3 75 3.67E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 Gene3D G3DSA:1.10.10.10 2 68 1.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 Gene3D G3DSA:3.90.1150.10 319 449 7.8E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 SMART SM00345 7 66 4.6E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 Gene3D G3DSA:3.40.640.10 104 318 3.3E-30 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS14830 1405bdb1696e4d52d60fc5ec06cadfbf 456 SUPERFAMILY SSF53383 65 446 3.3E-66 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS30165 7e542899bf68b3c2aae2586a33ea2136 235 Gene3D G3DSA:3.30.420.10 65 214 4.8E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS30165 7e542899bf68b3c2aae2586a33ea2136 235 Pfam PF13610 DDE domain 74 212 6.7E-50 T 29-03-2018 IPR032874 DDE domain CSW12_RS30165 7e542899bf68b3c2aae2586a33ea2136 235 SUPERFAMILY SSF53098 70 191 1.11E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29515 7e542899bf68b3c2aae2586a33ea2136 235 Gene3D G3DSA:3.30.420.10 65 214 4.8E-17 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29515 7e542899bf68b3c2aae2586a33ea2136 235 Pfam PF13610 DDE domain 74 212 6.7E-50 T 29-03-2018 IPR032874 DDE domain CSW12_RS29515 7e542899bf68b3c2aae2586a33ea2136 235 SUPERFAMILY SSF53098 70 191 1.11E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 Gene3D G3DSA:3.90.170.10 265 429 3.6E-68 T 29-03-2018 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 Pfam PF00709 Adenylosuccinate synthetase 4 420 6.8E-185 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 2.4E-192 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 211.421 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 SUPERFAMILY SSF52540 1 427 1.17E-176 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 29-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 Gene3D G3DSA:3.40.440.10 1 149 5.9E-55 T 29-03-2018 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 Gene3D G3DSA:3.40.440.10 150 264 3.9E-28 T 29-03-2018 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 SMART SM00788 3 422 2.9E-294 T 29-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CSW12_RS27200 799f8a03ba4e01fcdbb51494c22759fe 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 29-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 SUPERFAMILY SSF75217 1 243 4.91E-106 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 Gene3D G3DSA:3.40.1280.10 1 169 9.9E-80 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 1.0E-74 T 29-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 244 116.808 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 233 5.5E-104 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 PIRSF PIRSF000386 1 244 4.7E-107 T 29-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CSW12_RS08570 33b48eeb2b3dc375a5934b9d174c6d93 244 Gene3D G3DSA:1.10.1270.20 170 244 7.5E-36 T 29-03-2018 CSW12_RS26160 7f68bbeae9e7b524eec3949ffce981db 227 SUPERFAMILY SSF52540 46 220 3.29E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26160 7f68bbeae9e7b524eec3949ffce981db 227 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 27 227 2.2E-70 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CSW12_RS26160 7f68bbeae9e7b524eec3949ffce981db 227 Pfam PF13614 AAA domain 48 189 1.2E-13 T 29-03-2018 IPR025669 AAA domain CSW12_RS26160 7f68bbeae9e7b524eec3949ffce981db 227 Gene3D G3DSA:3.40.50.300 12 226 4.8E-36 T 29-03-2018 CSW12_RS10565 7334e0b6ba33621f0691ff5b86d7f140 344 Gene3D G3DSA:1.10.3470.10 15 343 3.1E-68 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS10565 7334e0b6ba33621f0691ff5b86d7f140 344 SUPERFAMILY SSF81345 13 339 4.97E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS10565 7334e0b6ba33621f0691ff5b86d7f140 344 Pfam PF01032 FecCD transport family 30 339 1.2E-89 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS21090 a1aa45fac0c7195c0647144c1f39e154 270 Gene3D G3DSA:3.40.50.300 36 269 2.1E-5 T 29-03-2018 CSW12_RS21090 a1aa45fac0c7195c0647144c1f39e154 270 Pfam PF03618 Kinase/pyrophosphorylase 6 260 8.4E-96 T 29-03-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CSW12_RS21090 a1aa45fac0c7195c0647144c1f39e154 270 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 266 60.707 T 29-03-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 Gene3D G3DSA:1.10.155.10 14 82 7.2E-8 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 Pfam PF03705 CheR methyltransferase, all-alpha domain 21 70 7.8E-12 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 SUPERFAMILY SSF53335 85 266 3.44E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 PRINTS PR00996 Glutamate methyltransferase family signature 78 90 1.9E-25 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 1.9E-25 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 PRINTS PR00996 Glutamate methyltransferase family signature 41 54 1.9E-25 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 PRINTS PR00996 Glutamate methyltransferase family signature 114 134 1.9E-25 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 PRINTS PR00996 Glutamate methyltransferase family signature 146 162 1.9E-25 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 1.9E-25 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 SUPERFAMILY SSF47757 15 87 1.16E-8 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 SMART SM00138 19 282 5.7E-40 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 Gene3D G3DSA:3.40.50.150 84 284 1.5E-39 T 29-03-2018 CSW12_RS04315 1af368da3629f6c516a5a5e1aeabd9e7 285 Pfam PF01739 CheR methyltransferase, SAM binding domain 85 263 3.8E-41 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CSW12_RS25290 90f9600319bc9ad5b603c023d427e859 338 Gene3D G3DSA:3.40.50.1980 172 338 1.7E-29 T 29-03-2018 CSW12_RS25290 90f9600319bc9ad5b603c023d427e859 338 Gene3D G3DSA:3.40.50.1980 32 171 1.2E-22 T 29-03-2018 CSW12_RS25290 90f9600319bc9ad5b603c023d427e859 338 SUPERFAMILY SSF53807 45 322 1.61E-53 T 29-03-2018 CSW12_RS25290 90f9600319bc9ad5b603c023d427e859 338 Pfam PF01497 Periplasmic binding protein 64 315 2.2E-37 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS03950 6c26f32adc82168d35831731283eb6c9 108 SUPERFAMILY SSF101386 31 84 4.3E-6 T 29-03-2018 CSW12_RS03950 6c26f32adc82168d35831731283eb6c9 108 Gene3D G3DSA:1.10.287.1080 4 93 5.2E-5 T 29-03-2018 CSW12_RS17930 1397eb671d863f798fca778133fdc364 280 Gene3D G3DSA:3.20.20.150 1 280 2.1E-46 T 29-03-2018 CSW12_RS17930 1397eb671d863f798fca778133fdc364 280 SUPERFAMILY SSF51658 1 259 3.32E-43 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CSW12_RS17930 1397eb671d863f798fca778133fdc364 280 Pfam PF01261 Xylose isomerase-like TIM barrel 22 232 1.3E-28 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 Gene3D G3DSA:3.40.605.10 240 415 1.7E-40 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 Gene3D G3DSA:3.40.605.10 2 239 3.9E-35 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 Pfam PF00171 Aldehyde dehydrogenase family 36 278 9.7E-12 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 SUPERFAMILY SSF53720 3 414 7.07E-111 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 41.726 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 343 - T 29-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 PIRSF PIRSF000151 1 415 3.7E-178 T 29-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CSW12_RS12750 90fd327956f19db01c8cf25c9d600765 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 404 9.2E-166 T 29-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS15240 b449aaef5640329215213b324b6a9ccc 155 Pfam PF04266 ASCH domain 36 150 1.7E-21 T 29-03-2018 IPR007374 ASCH domain CSW12_RS15240 b449aaef5640329215213b324b6a9ccc 155 SUPERFAMILY SSF88697 4 151 5.22E-50 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS15240 b449aaef5640329215213b324b6a9ccc 155 SMART SM01022 27 151 8.9E-32 T 29-03-2018 IPR007374 ASCH domain CSW12_RS15240 b449aaef5640329215213b324b6a9ccc 155 PIRSF PIRSF021320 2 154 1.5E-47 T 29-03-2018 IPR009326 Protein of unknown function DUF984 CSW12_RS15240 b449aaef5640329215213b324b6a9ccc 155 Gene3D G3DSA:3.10.400.10 4 153 1.3E-51 T 29-03-2018 CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 SUPERFAMILY SSF46785 2 93 6.35E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 SMART SM00418 16 93 7.3E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 Pfam PF01022 Bacterial regulatory protein, arsR family 23 65 2.5E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 6.9E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 6.9E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 6.9E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17850 ec5d51f1f1e1a096a9b4166b47abdfa8 102 Gene3D G3DSA:1.10.10.10 2 87 7.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 Pfam PF00149 Calcineurin-like phosphoesterase 41 269 2.4E-14 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 SUPERFAMILY SSF56300 33 341 2.58E-81 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 PRINTS PR01607 Apyrase family signature 36 54 8.9E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 PRINTS PR01607 Apyrase family signature 251 274 8.9E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 PRINTS PR01607 Apyrase family signature 465 484 8.9E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 PRINTS PR01607 Apyrase family signature 277 297 8.9E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 PRINTS PR01607 Apyrase family signature 394 417 8.9E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 PRINTS PR01607 Apyrase family signature 222 239 8.9E-26 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 Pfam PF02872 5'-nucleotidase, C-terminal domain 342 490 1.2E-48 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 SUPERFAMILY SSF55816 339 528 4.05E-57 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 Gene3D G3DSA:3.90.780.10 342 528 3.5E-60 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 ProSitePatterns PS00786 5'-nucleotidase signature 2. 114 125 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS07165 2e5b3c2fc25075241576744a336dc362 529 Gene3D G3DSA:3.60.21.10 27 341 3.0E-78 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 Gene3D G3DSA:1.10.340.30 22 118 5.9E-30 T 29-03-2018 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 SUPERFAMILY SSF48150 1 210 1.73E-74 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 6.1E-25 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 29-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 SMART SM00478 39 187 6.5E-68 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 PIRSF PIRSF001435 1 213 3.0E-59 T 29-03-2018 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 Gene3D G3DSA:1.10.1670.10 119 215 2.5E-31 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 Pfam PF00633 Helix-hairpin-helix motif 101 128 2.3E-9 T 29-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 TIGRFAM TIGR01083 nth: endonuclease III 6 196 1.8E-86 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CSW12_RS19855 09d8ac516af54123974008fd69b968bd 215 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.462 T 29-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 SMART SM00562 1 138 2.4E-89 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 36.505 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 8.7E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 8.7E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 8.7E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 8.7E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 8.7E-51 T 29-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 SUPERFAMILY SSF54919 1 148 6.55E-61 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 29-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 Gene3D G3DSA:3.30.70.141 1 148 4.2E-59 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS20025 a804f71c0a5f5ec571cdb838e1cbee08 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 3.1E-58 T 29-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS21900 27ea98454d72928483635610339def0f 225 Pfam PF04002 RadC-like JAB domain 104 223 3.3E-49 T 29-03-2018 IPR025657 RadC-like JAB domain CSW12_RS21900 27ea98454d72928483635610339def0f 225 SUPERFAMILY SSF47781 21 91 2.56E-7 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS21900 27ea98454d72928483635610339def0f 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 224 7.0E-83 T 29-03-2018 IPR001405 RadC protein CSW12_RS21900 27ea98454d72928483635610339def0f 225 Gene3D G3DSA:1.10.150.20 29 89 1.4E-5 T 29-03-2018 CSW12_RS21900 27ea98454d72928483635610339def0f 225 Gene3D G3DSA:3.40.140.10 100 225 7.4E-54 T 29-03-2018 CSW12_RS21900 27ea98454d72928483635610339def0f 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 29-03-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site CSW12_RS21900 27ea98454d72928483635610339def0f 225 SUPERFAMILY SSF102712 150 192 5.23E-5 T 29-03-2018 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 SUPERFAMILY SSF51445 1 467 3.16E-167 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 Pfam PF00232 Glycosyl hydrolase family 1 2 466 1.2E-166 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 370 378 - T 29-03-2018 IPR018120 Glycoside hydrolase family 1, active site CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 Gene3D G3DSA:3.20.20.80 1 469 6.8E-169 T 29-03-2018 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 370 378 9.7E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 9.7E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 9.7E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 9.7E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 9.7E-18 T 29-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CSW12_RS08985 e0f7abf611f8a0bb0812d71069f03c3e 469 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 29-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CSW12_RS00400 85246e04570a8cd1fd15c767d278b052 287 Pfam PF01391 Collagen triple helix repeat (20 copies) 203 255 8.2E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS00400 85246e04570a8cd1fd15c767d278b052 287 Pfam PF01391 Collagen triple helix repeat (20 copies) 163 215 7.4E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS00400 85246e04570a8cd1fd15c767d278b052 287 Gene3D G3DSA:2.160.20.50 204 266 5.4E-11 T 29-03-2018 CSW12_RS00400 85246e04570a8cd1fd15c767d278b052 287 Gene3D G3DSA:2.160.20.50 152 203 8.1E-7 T 29-03-2018 CSW12_RS06130 a868e924ae40fa6cbb433d5efb0537a6 397 SUPERFAMILY SSF51905 28 251 2.1E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS06130 a868e924ae40fa6cbb433d5efb0537a6 397 SUPERFAMILY SSF51905 344 387 2.1E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS06130 a868e924ae40fa6cbb433d5efb0537a6 397 Gene3D G3DSA:3.30.9.10 110 343 2.0E-17 T 29-03-2018 CSW12_RS06130 a868e924ae40fa6cbb433d5efb0537a6 397 Pfam PF01266 FAD dependent oxidoreductase 29 380 4.6E-42 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS06130 a868e924ae40fa6cbb433d5efb0537a6 397 Gene3D G3DSA:3.40.50.720 27 109 8.0E-6 T 29-03-2018 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 204 5.0E-43 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Gene3D G3DSA:3.40.50.720 2 205 8.5E-39 T 29-03-2018 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 SUPERFAMILY SSF48179 356 458 3.74E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 SUPERFAMILY SSF52096 482 790 2.84E-38 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Gene3D G3DSA:1.10.1040.10 363 476 2.1E-12 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 SUPERFAMILY SSF51735 1 205 4.27E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Gene3D G3DSA:3.90.226.10 477 792 3.0E-35 T 29-03-2018 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 207 304 9.5E-10 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Gene3D G3DSA:1.10.1040.10 206 303 8.4E-16 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 Pfam PF00378 Enoyl-CoA hydratase/isomerase 489 621 1.2E-11 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CSW12_RS24830 c06515a9ae41b8b0eb1614ca26ae13d1 793 SUPERFAMILY SSF48179 205 324 1.02E-20 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 SUPERFAMILY SSF52283 12 142 1.36E-30 T 29-03-2018 CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 158 186 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 SUPERFAMILY SSF51735 113 298 9.74E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 Gene3D G3DSA:3.40.50.720 124 300 2.6E-53 T 29-03-2018 CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 328 1.0E-28 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 Gene3D G3DSA:3.40.50.720 11 123 2.0E-26 T 29-03-2018 CSW12_RS24305 03ecd65f077207238fad3da0d7b7bd30 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 297 2.2E-64 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Gene3D G3DSA:1.10.150.20 241 314 2.3E-27 T 29-03-2018 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF56553 50 171 1.31E-44 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF47789 247 313 9.29E-25 T 29-03-2018 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 4.0E-127 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 5.8E-24 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF55257 146 230 7.06E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 SUPERFAMILY SSF55257 5 54 7.06E-33 T 29-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 6.7E-25 T 29-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 SMART SM00662 20 227 1.9E-107 T 29-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.78 T 29-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 2.4E-29 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 6.0E-26 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Gene3D G3DSA:3.30.1360.10 1 86 2.0E-20 T 29-03-2018 CSW12_RS28120 da80a6f8af08c7570750a95ef56c673e 314 Gene3D G3DSA:3.30.1360.10 107 224 6.0E-27 T 29-03-2018 CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 PIRSF PIRSF001589 1 585 6.7E-141 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 Gene3D G3DSA:3.60.20.10 1 226 1.6E-55 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 Pfam PF13537 Glutamine amidotransferase domain 48 169 9.6E-46 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 5.1E-168 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 SUPERFAMILY SSF56235 1 226 1.03E-65 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 Gene3D G3DSA:3.40.50.620 227 582 2.5E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 SUPERFAMILY SSF52402 231 396 3.67E-72 T 29-03-2018 CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 SUPERFAMILY SSF52402 454 576 3.67E-72 T 29-03-2018 CSW12_RS05040 7a44af4aead5b0d73a24d3ef9c5b1284 592 Pfam PF00733 Asparagine synthase 243 576 2.2E-92 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CSW12_RS07330 dcec07a1e7b1879c1a066a8f0299d7c2 138 Pfam PF13782 Stage V sporulation protein AB 26 134 3.6E-35 T 29-03-2018 IPR020144 Stage V sporulation protein AB CSW12_RS07330 dcec07a1e7b1879c1a066a8f0299d7c2 138 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 1 138 6.0E-60 T 29-03-2018 IPR020144 Stage V sporulation protein AB CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 441 1.2E-59 T 29-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 SUPERFAMILY SSF48013 2 127 4.06E-39 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 321 333 2.9E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 238 2.9E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 253 263 2.9E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 371 387 2.9E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 425 442 2.9E-31 T 29-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 SUPERFAMILY SSF53335 136 443 8.9E-76 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 Gene3D G3DSA:1.10.940.10 1 140 4.5E-33 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 320 331 - T 29-03-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 Gene3D G3DSA:3.40.50.150 233 444 3.0E-60 T 29-03-2018 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 6 443 1.5E-148 T 29-03-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 Gene3D G3DSA:3.30.70.1170 177 232 1.3E-8 T 29-03-2018 CSW12_RS08445 a9b1fb95dcb3bcc8ced897ae9fca0e4a 444 Pfam PF01029 NusB family 4 125 7.2E-32 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 Gene3D G3DSA:1.10.1040.10 186 283 8.0E-34 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 SUPERFAMILY SSF48179 185 283 1.11E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 SUPERFAMILY SSF51735 3 185 1.53E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 208 - T 29-03-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 1.7E-68 T 29-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 PIRSF PIRSF000105 1 283 1.2E-95 T 29-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 7.0E-36 T 29-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CSW12_RS26510 be828d1e4b557457576f9435cb0abbfc 283 Gene3D G3DSA:3.40.50.720 2 185 2.9E-61 T 29-03-2018 CSW12_RS03955 7596cd027e3db28676681d5045fa91a7 287 Pfam PF07261 Replication initiation and membrane attachment 171 239 2.7E-15 T 29-03-2018 IPR006343 DnaD domain CSW12_RS03955 7596cd027e3db28676681d5045fa91a7 287 Gene3D G3DSA:1.10.10.630 169 239 2.0E-19 T 29-03-2018 IPR034829 DnaD-like domain CSW12_RS03955 7596cd027e3db28676681d5045fa91a7 287 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 171 238 5.0E-18 T 29-03-2018 IPR006343 DnaD domain CSW12_RS03955 7596cd027e3db28676681d5045fa91a7 287 SUPERFAMILY SSF158499 170 231 6.54E-16 T 29-03-2018 IPR006343 DnaD domain CSW12_RS30945 8e162e20388b79b14a4bf9d6d7907908 905 Pfam PF12696 TraM recognition site of TraD and TraG 557 673 2.7E-28 T 29-03-2018 IPR032689 TraD/TraG, TraM recognition site CSW12_RS30945 8e162e20388b79b14a4bf9d6d7907908 905 Gene3D G3DSA:3.40.50.300 87 694 8.5E-31 T 29-03-2018 CSW12_RS30945 8e162e20388b79b14a4bf9d6d7907908 905 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 151 416 6.6E-24 T 29-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CSW12_RS30945 8e162e20388b79b14a4bf9d6d7907908 905 SUPERFAMILY SSF52540 188 361 2.12E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30945 8e162e20388b79b14a4bf9d6d7907908 905 SUPERFAMILY SSF52540 510 677 2.12E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 473 65.05 T 29-03-2018 IPR022825 Lactate utilization protein B CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 311 322 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Gene3D G3DSA:3.30.70.20 284 316 0.0078 T 29-03-2018 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Pfam PF13183 4Fe-4S dicluster domain 309 375 2.9E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Gene3D G3DSA:3.30.70.20 317 366 9.9E-8 T 29-03-2018 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Gene3D G3DSA:3.30.70.20 367 383 0.27 T 29-03-2018 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Pfam PF11870 Domain of unknown function (DUF3390) 383 469 5.1E-22 T 29-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 SUPERFAMILY SSF46548 280 391 3.49E-17 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Pfam PF02589 LUD domain 71 293 3.9E-54 T 29-03-2018 IPR003741 LUD domain CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 SUPERFAMILY SSF100950 135 294 3.31E-36 T 29-03-2018 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 SUPERFAMILY SSF100950 64 89 3.31E-36 T 29-03-2018 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 453 5.6E-206 T 29-03-2018 IPR004452 4Fe-4S binding protein GO:0019516 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Gene3D G3DSA:3.40.50.10420 64 137 1.3E-7 T 29-03-2018 CSW12_RS06060 65cf56b51ffcfcf8986e87a00a13a3d0 473 Gene3D G3DSA:3.40.50.10420 138 283 4.4E-44 T 29-03-2018 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 Gene3D G3DSA:3.40.50.2300 1 132 1.6E-10 T 29-03-2018 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 Pfam PF00072 Response regulator receiver domain 5 109 3.4E-7 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 SMART SM00850 136 237 1.4E-29 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 Gene3D G3DSA:2.20.25.10 199 236 9.6E-10 T 29-03-2018 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 Pfam PF04397 LytTr DNA-binding domain 138 236 1.6E-27 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 SMART SM00448 1 112 0.0042 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 Gene3D G3DSA:2.40.50.40 133 198 3.7E-18 T 29-03-2018 CSW12_RS26870 0a10032204c034193a0c2df5882a4d16 238 SUPERFAMILY SSF52172 1 169 1.57E-14 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS00245 734b26e4edd956651e43cc97a5d231af 180 Gene3D G3DSA:1.10.443.10 6 176 1.4E-32 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS00245 734b26e4edd956651e43cc97a5d231af 180 Pfam PF00589 Phage integrase family 9 167 3.3E-23 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS00245 734b26e4edd956651e43cc97a5d231af 180 SUPERFAMILY SSF56349 5 178 1.32E-37 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 SMART SM00829 8 326 1.2E-23 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 87 1.6E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 SUPERFAMILY SSF50129 3 145 4.72E-33 T 29-03-2018 IPR011032 GroES-like CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 Gene3D G3DSA:3.90.180.10 253 329 1.3E-8 T 29-03-2018 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 Gene3D G3DSA:3.40.50.720 153 252 1.2E-13 T 29-03-2018 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 SUPERFAMILY SSF51735 113 293 2.87E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 Pfam PF13602 Zinc-binding dehydrogenase 183 326 2.4E-36 T 29-03-2018 CSW12_RS10405 60cb0f400228d6253db0c6f6b564cce2 329 Gene3D G3DSA:3.90.180.10 2 152 3.3E-48 T 29-03-2018 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 Gene3D G3DSA:3.40.50.2030 253 428 1.8E-54 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 428 16.558 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 Gene3D G3DSA:3.40.50.2030 114 252 3.5E-63 T 29-03-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 Pfam PF03063 Prismane/CO dehydrogenase family 80 423 6.2E-104 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 Pfam PF03063 Prismane/CO dehydrogenase family 1 79 3.6E-14 T 29-03-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 SUPERFAMILY SSF56821 1 427 4.4E-149 T 29-03-2018 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 23 427 7.7E-170 T 29-03-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS10730 d82590833ec925b9fdd9ef8f8ca34aea 428 Gene3D G3DSA:1.20.1270.20 28 111 2.0E-29 T 29-03-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 SUPERFAMILY SSF57783 576 613 3.57E-13 T 29-03-2018 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:2.70.20.10 327 456 6.2E-42 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01751 Toprim domain 5 113 4.4E-30 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 2.1E-265 T 29-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 636 55.817 T 29-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 576 612 9.8E-15 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 656 8.5E-12 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 686 0.023 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:1.10.460.10 135 326 1.1E-49 T 29-03-2018 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:3.40.50.140 2 129 3.1E-38 T 29-03-2018 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 SMART SM00436 104 192 1.6E-52 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 SUPERFAMILY SSF56712 4 589 1.96E-202 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:3.30.65.10 557 612 3.6E-16 T 29-03-2018 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:3.30.65.10 654 691 0.0014 T 29-03-2018 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Gene3D G3DSA:3.30.65.10 613 653 3.4E-7 T 29-03-2018 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 SMART SM00437 242 510 1.9E-123 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 SMART SM00493 3 103 7.7E-34 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 5.0E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 5.0E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 5.0E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 5.0E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 5.0E-36 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS08610 cb66e64662061da68995fe3f09dfcf5e 692 Pfam PF01131 DNA topoisomerase 128 547 1.5E-136 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS13425 70d5090730a6da32b9a3568f5c2d33fc 118 Pfam PF04977 Septum formation initiator 41 117 6.7E-17 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CSW12_RS13425 70d5090730a6da32b9a3568f5c2d33fc 118 Gene3D G3DSA:1.20.5.730 45 105 1.3E-4 T 29-03-2018 CSW12_RS19355 6e43ef8396f19c64de8e417d6c2a8fbe 137 Pfam PF00460 Flagella basal body rod protein 5 32 4.9E-5 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CSW12_RS19355 6e43ef8396f19c64de8e417d6c2a8fbe 137 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 89 130 1.1E-9 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CSW12_RS19355 6e43ef8396f19c64de8e417d6c2a8fbe 137 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 2 136 4.9E-39 T 29-03-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 ProSitePatterns PS00737 Thiolases signature 2. 307 323 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 359 1.4E-116 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 PIRSF PIRSF000429 1 362 5.1E-115 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 Pfam PF00108 Thiolase, N-terminal domain 5 230 8.1E-49 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 Pfam PF02803 Thiolase, C-terminal domain 239 360 7.0E-39 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 Gene3D G3DSA:3.40.47.10 1 238 1.6E-42 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 SUPERFAMILY SSF53901 194 361 7.95E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 SUPERFAMILY SSF53901 5 118 7.95E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS09620 632a654eb98d050e7905da07f7588ccc 363 Gene3D G3DSA:3.40.47.10 239 358 1.2E-25 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 SUPERFAMILY SSF56801 17 553 1.7E-165 T 29-03-2018 CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 Gene3D G3DSA:3.40.50.980 22 216 5.7E-44 T 29-03-2018 CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 Gene3D G3DSA:3.30.300.30 454 563 1.2E-28 T 29-03-2018 CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 4.3E-21 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 Gene3D G3DSA:2.30.38.10 369 452 9.7E-29 T 29-03-2018 CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 Pfam PF00501 AMP-binding enzyme 31 458 8.4E-121 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS22225 49cc7b2367892cf75f2883baa3b63229 563 Gene3D G3DSA:3.40.50.980 217 368 3.0E-48 T 29-03-2018 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 377 2.5E-10 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 Pfam PF08245 Mur ligase middle domain 117 290 1.7E-31 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 Gene3D G3DSA:3.40.1190.10 102 308 1.1E-50 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 SUPERFAMILY SSF53244 310 449 8.47E-44 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 SUPERFAMILY SSF51984 10 100 2.49E-17 T 29-03-2018 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 449 35.834 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 SUPERFAMILY SSF53623 103 308 1.68E-49 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 447 5.5E-138 T 29-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 Gene3D G3DSA:3.90.190.20 315 448 1.7E-37 T 29-03-2018 CSW12_RS08195 5970fd1ff5d24cde067b390b00327391 450 Gene3D G3DSA:3.40.50.720 2 101 1.6E-16 T 29-03-2018 CSW12_RS21685 2a66584fa2fad542c3901bcf582c3fc3 779 SUPERFAMILY SSF64182 57 452 1.12E-123 T 29-03-2018 CSW12_RS21685 2a66584fa2fad542c3901bcf582c3fc3 779 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 29 562 8.4E-184 T 29-03-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CSW12_RS21685 2a66584fa2fad542c3901bcf582c3fc3 779 Pfam PF01368 DHH family 83 209 1.8E-9 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS21685 2a66584fa2fad542c3901bcf582c3fc3 779 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 568 766 1.1E-65 T 29-03-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal CSW12_RS21685 2a66584fa2fad542c3901bcf582c3fc3 779 Gene3D G3DSA:3.90.1640.10 64 238 6.7E-27 T 29-03-2018 CSW12_RS21685 2a66584fa2fad542c3901bcf582c3fc3 779 Pfam PF02272 DHHA1 domain 315 439 1.1E-20 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Gene3D G3DSA:3.20.20.80 290 502 7.0E-50 T 29-03-2018 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Gene3D G3DSA:2.60.40.1180 507 586 2.5E-16 T 29-03-2018 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Pfam PF16657 Maltogenic Amylase, C-terminal domain 507 583 6.2E-17 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Gene3D G3DSA:3.90.400.10 262 289 5.6E-22 T 29-03-2018 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Gene3D G3DSA:3.20.20.470 122 227 3.3E-36 T 29-03-2018 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Pfam PF00128 Alpha amylase, catalytic domain 173 469 4.0E-81 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Gene3D G3DSA:3.40.640.10 228 261 0.0011 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 SUPERFAMILY SSF51445 68 503 1.08E-125 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 121 6.4E-49 T 29-03-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 SUPERFAMILY SSF51011 507 585 3.42E-19 T 29-03-2018 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 SMART SM00642 139 497 6.3E-123 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS07660 4f0589bbd0c3dac276c441f19437ec43 586 Gene3D G3DSA:2.60.40.10 1 121 1.2E-47 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS24410 fb20687ee2b21cc5707d8226bbb56e96 168 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS24410 fb20687ee2b21cc5707d8226bbb56e96 168 PRINTS PR00502 NUDIX hydrolase family signature 36 50 2.7E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS24410 fb20687ee2b21cc5707d8226bbb56e96 168 PRINTS PR00502 NUDIX hydrolase family signature 50 65 2.7E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS24410 fb20687ee2b21cc5707d8226bbb56e96 168 SUPERFAMILY SSF55811 6 129 1.76E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS24410 fb20687ee2b21cc5707d8226bbb56e96 168 Pfam PF00293 NUDIX domain 9 118 2.3E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS24410 fb20687ee2b21cc5707d8226bbb56e96 168 Gene3D G3DSA:3.90.79.10 3 139 2.4E-21 T 29-03-2018 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 Gene3D G3DSA:3.40.1390.20 3 132 2.9E-45 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 6.1E-78 T 29-03-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 SUPERFAMILY SSF53795 132 298 3.02E-42 T 29-03-2018 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.73 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 302 1.5E-120 T 29-03-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 Gene3D G3DSA:3.40.50.300 133 307 1.4E-47 T 29-03-2018 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 Pfam PF02603 HPr Serine kinase N terminus 4 127 1.1E-41 T 29-03-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CSW12_RS25510 4ac0dd79f7610f1d5aa6a02659049ede 309 SUPERFAMILY SSF75138 1 131 1.96E-41 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Gene3D G3DSA:2.30.30.40 213 263 6.1E-4 T 29-03-2018 CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Gene3D G3DSA:3.40.630.40 332 530 2.2E-55 T 29-03-2018 CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 337 521 5.0E-47 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 SMART SM00646 402 521 6.1E-38 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Pfam PF00395 S-layer homology domain 151 192 2.3E-7 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Pfam PF00395 S-layer homology domain 89 131 4.9E-10 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Pfam PF00395 S-layer homology domain 28 71 1.7E-14 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 SUPERFAMILY SSF53187 335 526 2.07E-49 T 29-03-2018 CSW12_RS03800 36661433d650d32a71e49043e3fbcc67 535 Gene3D G3DSA:2.40.50.110 264 325 6.2E-5 T 29-03-2018 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 542 2.7E-43 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 Gene3D G3DSA:3.40.50.970 7 197 1.8E-52 T 29-03-2018 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 16 553 2.9E-264 T 29-03-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 Gene3D G3DSA:3.40.50.970 361 561 9.2E-40 T 29-03-2018 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 Gene3D G3DSA:3.40.50.1220 198 360 7.7E-25 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 181 2.8E-55 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 SUPERFAMILY SSF52518 12 182 4.32E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 433 452 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 SUPERFAMILY SSF52467 194 361 6.29E-35 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 SUPERFAMILY SSF52518 375 552 2.56E-59 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS03685 7b0ddfcd4bb8103b86aedc3f2c478c48 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 333 4.9E-27 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.30.420.40 6 159 5.3E-38 T 29-03-2018 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.90.640.10 194 251 6.1E-28 T 29-03-2018 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 Pfam PF06723 MreB/Mbl protein 9 334 6.5E-152 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 SUPERFAMILY SSF53067 149 332 6.79E-51 T 29-03-2018 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 7 335 4.8E-161 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 SUPERFAMILY SSF53067 8 146 3.11E-39 T 29-03-2018 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 46 64 3.1E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 66 89 3.1E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 186 206 3.1E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 299 325 3.1E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 131 150 3.1E-60 T 29-03-2018 IPR004753 Cell shape determining protein MreB GO:0000902 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.30.420.40 160 193 0.0013 T 29-03-2018 CSW12_RS21895 0af65f59cab7268581594fc017611dec 339 Gene3D G3DSA:3.30.420.40 252 316 4.1E-10 T 29-03-2018 CSW12_RS24035 a3812c168b54cf7d9adae218eec2395d 317 PIRSF PIRSF005355 14 316 8.4E-86 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CSW12_RS24035 a3812c168b54cf7d9adae218eec2395d 317 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 30 306 3.9E-38 T 29-03-2018 CSW12_RS24035 a3812c168b54cf7d9adae218eec2395d 317 Pfam PF01040 UbiA prenyltransferase family 38 271 3.3E-35 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CSW12_RS24035 a3812c168b54cf7d9adae218eec2395d 317 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 21 311 19.425 T 29-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CSW12_RS01920 aa67026ec220b0eebd3581641e02eda2 125 Pfam PF02566 OsmC-like protein 22 118 4.8E-21 T 29-03-2018 IPR003718 OsmC/Ohr family CSW12_RS01920 aa67026ec220b0eebd3581641e02eda2 125 Gene3D G3DSA:3.30.300.20 1 125 5.5E-24 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS01920 aa67026ec220b0eebd3581641e02eda2 125 SUPERFAMILY SSF82784 22 124 3.27E-25 T 29-03-2018 IPR003718 OsmC/Ohr family CSW12_RS18155 96997db6a3fc36518d46392f6bade293 467 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 441 3.4E-170 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CSW12_RS18155 96997db6a3fc36518d46392f6bade293 467 PIRSF PIRSF006446 1 467 3.9E-179 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 SUPERFAMILY SSF51569 1 291 1.36E-85 T 29-03-2018 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 SMART SM01130 3 293 1.2E-100 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 1.2E-20 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.2E-20 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.2E-20 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.2E-20 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 PIRSF PIRSF001365 1 298 6.5E-96 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 Pfam PF00701 Dihydrodipicolinate synthetase family 4 291 9.9E-71 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 9 290 6.0E-69 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS13520 0503e7a1941a4a69d3cb5669436c9f00 298 Gene3D G3DSA:3.20.20.70 1 294 1.5E-86 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS04385 a159fc195a107c5628caae3ee1ed5b66 413 Pfam PF00149 Calcineurin-like phosphoesterase 5 203 2.3E-16 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS04385 a159fc195a107c5628caae3ee1ed5b66 413 SUPERFAMILY SSF56300 5 297 3.8E-57 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS04385 a159fc195a107c5628caae3ee1ed5b66 413 Gene3D G3DSA:3.60.21.10 83 252 4.1E-23 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS04385 a159fc195a107c5628caae3ee1ed5b66 413 Gene3D G3DSA:3.60.21.10 1 82 2.4E-15 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS04385 a159fc195a107c5628caae3ee1ed5b66 413 PIRSF PIRSF033091 1 413 1.1E-159 T 29-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 Gene3D G3DSA:1.20.120.530 81 223 2.4E-19 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 SUPERFAMILY SSF48008 88 216 4.45E-17 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 SUPERFAMILY SSF46785 12 96 3.86E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 SMART SM00895 87 211 7.7E-9 T 29-03-2018 IPR011711 GntR, C-terminal CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.8E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.8E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 Gene3D G3DSA:1.10.10.10 4 79 2.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 76 1.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 SMART SM00345 19 77 2.0E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS19020 52ce04293df1f96189bfd2ffb2ce618f 223 Pfam PF07729 FCD domain 88 207 1.9E-21 T 29-03-2018 IPR011711 GntR, C-terminal CSW12_RS16575 4d6ce00ed3393731c87c797f9ef65f82 315 Pfam PF00005 ABC transporter 19 164 7.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS16575 4d6ce00ed3393731c87c797f9ef65f82 315 SMART SM00382 27 214 2.1E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS16575 4d6ce00ed3393731c87c797f9ef65f82 315 Gene3D G3DSA:3.40.50.300 1 291 1.0E-79 T 29-03-2018 CSW12_RS16575 4d6ce00ed3393731c87c797f9ef65f82 315 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS16575 4d6ce00ed3393731c87c797f9ef65f82 315 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 14 284 1.4E-101 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CSW12_RS16575 4d6ce00ed3393731c87c797f9ef65f82 315 SUPERFAMILY SSF52540 1 244 4.56E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 Pfam PF01713 Smr domain 711 786 1.2E-19 T 29-03-2018 IPR002625 Smr domain CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 785 22.108 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 Gene3D G3DSA:1.10.1420.10 16 289 2.7E-5 T 29-03-2018 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 SMART SM00463 708 786 9.2E-19 T 29-03-2018 IPR002625 Smr domain CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 Gene3D G3DSA:3.40.50.300 292 558 1.5E-35 T 29-03-2018 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 Pfam PF00488 MutS domain V 331 512 6.1E-35 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 SUPERFAMILY SSF48334 17 287 4.45E-31 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 SMART SM00533 9 315 5.0E-35 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 SMART SM00534 328 513 2.6E-76 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 SUPERFAMILY SSF160443 709 780 1.26E-9 T 29-03-2018 IPR002625 Smr domain CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 PIRSF PIRSF005814 1 786 3.6E-278 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 786 3.7E-272 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CSW12_RS22370 4c4e0a3203bf86fb1d7f10bbf9054fd6 786 SUPERFAMILY SSF52540 292 514 2.4E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 252 281 1.2E-45 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 99 114 1.2E-45 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 44 64 1.2E-45 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 136 156 1.2E-45 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 PRINTS PR00113 Alkaline phosphatase signature 186 196 1.2E-45 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 Gene3D G3DSA:3.40.720.10 18 461 9.3E-130 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 ProSitePatterns PS00123 Alkaline phosphatase active site. 99 107 - T 29-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 SMART SM00098 45 454 1.6E-198 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 Pfam PF00245 Alkaline phosphatase 44 450 1.0E-133 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS21360 2c84e4d7102bb11b282b785c14521a61 461 SUPERFAMILY SSF53649 39 452 1.02E-130 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS02780 b73b41cb8d611cb00d8239637da62cca 309 Pfam PF12849 PBP superfamily domain 52 287 4.0E-36 T 29-03-2018 IPR024370 PBP domain CSW12_RS02780 b73b41cb8d611cb00d8239637da62cca 309 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 12 304 1.7E-97 T 29-03-2018 IPR011862 Phosphate binding protein GO:0006810 CSW12_RS02780 b73b41cb8d611cb00d8239637da62cca 309 Gene3D G3DSA:3.40.190.10 149 265 3.4E-34 T 29-03-2018 CSW12_RS02780 b73b41cb8d611cb00d8239637da62cca 309 SUPERFAMILY SSF53850 57 305 3.01E-70 T 29-03-2018 CSW12_RS02780 b73b41cb8d611cb00d8239637da62cca 309 Gene3D G3DSA:3.40.190.10 51 148 4.6E-8 T 29-03-2018 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 3.6E-120 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 SUPERFAMILY SSF53335 3 274 1.83E-88 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 Gene3D G3DSA:3.40.50.150 55 275 6.1E-46 T 29-03-2018 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 Pfam PF17284 Spermidine synthase tetramerisation domain 3 55 7.2E-20 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 Pfam PF01564 Spermine/spermidine synthase domain 58 236 5.1E-68 T 29-03-2018 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 Gene3D G3DSA:2.30.140.10 4 51 2.1E-19 T 29-03-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS26635 d1c1af3f3fe1f21aef1c70053d144582 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 42.126 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 458 35.916 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 SUPERFAMILY SSF63418 7 103 4.71E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 457 2.7E-139 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Gene3D G3DSA:3.40.1190.10 96 314 1.4E-58 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Pfam PF01225 Mur ligase family, catalytic domain 27 101 9.0E-11 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Pfam PF08245 Mur ligase middle domain 111 298 5.8E-49 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 SUPERFAMILY SSF53623 106 315 1.44E-52 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 SUPERFAMILY SSF53244 319 457 2.56E-36 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 320 398 4.1E-16 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Gene3D G3DSA:3.40.1390.10 1 95 1.4E-28 T 29-03-2018 CSW12_RS28665 73a26a9dd96eb6571d6a817b0c910022 458 Gene3D G3DSA:3.90.190.20 317 458 6.9E-42 T 29-03-2018 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 3.2E-40 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 5.8E-87 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 SUPERFAMILY SSF48179 161 268 1.38E-38 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 Gene3D G3DSA:3.40.50.720 1 163 3.1E-30 T 29-03-2018 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 27.337 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 SUPERFAMILY SSF51735 3 160 2.51E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 2.8E-17 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 PIRSF PIRSF000193 2 269 3.8E-86 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS12735 704596a836ae89a5c982808bb4f9981b 272 Gene3D G3DSA:1.10.3730.10 164 271 3.2E-44 T 29-03-2018 CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 PIRSF PIRSF002888 2 328 8.8E-58 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 SUPERFAMILY SSF103039 47 234 2.17E-5 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 SUPERFAMILY SSF101801 259 325 2.35E-8 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 258 325 4.6E-13 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 Gene3D G3DSA:2.30.330.10 242 328 1.2E-11 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 Pfam PF02154 Flagellar motor switch protein FliM 40 234 1.9E-23 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 Gene3D G3DSA:3.40.1550.10 50 241 3.7E-19 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 119 138 8.8E-5 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 8.8E-5 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CSW12_RS19255 ef638c35bdf8e19ee9b01cd8174b895f 328 PRINTS PR00955 Flagellar motor switch protein FliM signature 216 234 8.8E-5 T 29-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CSW12_RS16675 cc3db2fb1a1799e990629682d7324537 115 SUPERFAMILY SSF57884 72 115 5.1E-5 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CSW12_RS16675 cc3db2fb1a1799e990629682d7324537 115 Gene3D G3DSA:3.40.10.10 47 115 4.0E-19 T 29-03-2018 IPR035451 Ada-like domain CSW12_RS24665 2f3a9273ccdc006fd1787651b4206eec 159 Pfam PF04073 Aminoacyl-tRNA editing domain 44 142 8.9E-21 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS24665 2f3a9273ccdc006fd1787651b4206eec 159 SUPERFAMILY SSF55826 2 144 5.23E-34 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS24665 2f3a9273ccdc006fd1787651b4206eec 159 Gene3D G3DSA:3.90.960.10 2 158 9.4E-24 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS11205 2efddc1fe4215a42955c550fe49e51d9 126 Gene3D G3DSA:3.10.180.10 1 126 1.5E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS11205 2efddc1fe4215a42955c550fe49e51d9 126 SUPERFAMILY SSF54593 1 125 2.15E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS11205 2efddc1fe4215a42955c550fe49e51d9 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 3.2E-17 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 SUPERFAMILY SSF52440 8 93 5.04E-27 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 SUPERFAMILY SSF56059 106 304 1.08E-64 T 29-03-2018 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 Gene3D G3DSA:3.40.50.20 8 94 3.0E-25 T 29-03-2018 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 10 359 44.075 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 6 74 8.3E-6 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 361 1.7E-133 T 29-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 Pfam PF02222 ATP-grasp domain 115 284 3.6E-61 T 29-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 Gene3D G3DSA:3.30.470.20 185 370 2.4E-41 T 29-03-2018 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 SUPERFAMILY SSF51246 308 376 1.02E-16 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CSW12_RS00025 763b0c191318d40bae4a7003d7f520c1 383 Gene3D G3DSA:3.30.1490.20 112 184 5.3E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS14935 24406f58a98737b281b502ffb8d07236 245 Gene3D G3DSA:3.40.50.1580 2 238 2.3E-38 T 29-03-2018 CSW12_RS14935 24406f58a98737b281b502ffb8d07236 245 Pfam PF01048 Phosphorylase superfamily 12 234 1.2E-38 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS14935 24406f58a98737b281b502ffb8d07236 245 SUPERFAMILY SSF53167 10 235 5.76E-49 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS14935 24406f58a98737b281b502ffb8d07236 245 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 12 219 2.8E-21 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS25350 81faaeee3b65cc7d5d01c892312ece82 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 250 40.411 T 29-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25350 81faaeee3b65cc7d5d01c892312ece82 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 29-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25350 81faaeee3b65cc7d5d01c892312ece82 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.0E-60 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25350 81faaeee3b65cc7d5d01c892312ece82 251 Pfam PF00121 Triosephosphate isomerase 5 246 1.9E-91 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25350 81faaeee3b65cc7d5d01c892312ece82 251 Gene3D G3DSA:3.20.20.70 1 251 1.2E-101 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS25350 81faaeee3b65cc7d5d01c892312ece82 251 SUPERFAMILY SSF51351 1 249 1.57E-92 T 29-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS11570 356ba1d0488e2029b60aae3a25d35c9f 83 Gene3D G3DSA:2.60.120.10 1 83 4.4E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS11570 356ba1d0488e2029b60aae3a25d35c9f 83 SUPERFAMILY SSF51182 14 81 1.6E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS11570 356ba1d0488e2029b60aae3a25d35c9f 83 Pfam PF07883 Cupin domain 11 71 2.3E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS00775 abf3fbe3c71b537106d7958f4dca2cea 222 SUPERFAMILY SSF51391 9 217 9.16E-68 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00775 abf3fbe3c71b537106d7958f4dca2cea 222 Gene3D G3DSA:3.20.20.70 16 221 4.7E-47 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS00775 abf3fbe3c71b537106d7958f4dca2cea 222 Pfam PF02581 Thiamine monophosphate synthase 18 201 9.6E-62 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00775 abf3fbe3c71b537106d7958f4dca2cea 222 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 16 219 28.424 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00775 abf3fbe3c71b537106d7958f4dca2cea 222 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 18 213 4.5E-66 T 29-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS06235 b4d58feeec4e1564818955e5981756f5 177 SUPERFAMILY SSF109854 3 173 1.68E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS06235 b4d58feeec4e1564818955e5981756f5 177 Pfam PF12867 DinB superfamily 17 166 5.1E-16 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS06235 b4d58feeec4e1564818955e5981756f5 177 Gene3D G3DSA:1.20.120.450 4 177 1.0E-21 T 29-03-2018 CSW12_RS30045 49aa1b2a7008cdf6711539382a0fed15 188 SUPERFAMILY SSF159941 1 182 1.7E-50 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS30045 49aa1b2a7008cdf6711539382a0fed15 188 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 3 179 4.4E-48 T 29-03-2018 IPR012912 Plasmid pRiA4b, Orf3 CSW12_RS30045 49aa1b2a7008cdf6711539382a0fed15 188 Gene3D G3DSA:3.10.290.30 1 182 8.0E-49 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS29555 49aa1b2a7008cdf6711539382a0fed15 188 SUPERFAMILY SSF159941 1 182 1.7E-50 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS29555 49aa1b2a7008cdf6711539382a0fed15 188 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 3 179 4.4E-48 T 29-03-2018 IPR012912 Plasmid pRiA4b, Orf3 CSW12_RS29555 49aa1b2a7008cdf6711539382a0fed15 188 Gene3D G3DSA:3.10.290.30 1 182 8.0E-49 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS25505 603c61518fdbc5d125034ce62592990f 270 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 137 149 - T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CSW12_RS25505 603c61518fdbc5d125034ce62592990f 270 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 260 3.5E-85 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CSW12_RS25505 603c61518fdbc5d125034ce62592990f 270 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 8 261 17.744 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CSW12_RS25505 603c61518fdbc5d125034ce62592990f 270 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 256 1.6E-78 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CSW12_RS19580 2fb7ce232a3f4cd798c77d291304529a 219 Gene3D G3DSA:3.30.420.10 71 211 1.1E-23 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS19580 2fb7ce232a3f4cd798c77d291304529a 219 Pfam PF13456 Reverse transcriptase-like 78 205 4.3E-15 T 29-03-2018 CSW12_RS19580 2fb7ce232a3f4cd798c77d291304529a 219 SUPERFAMILY SSF53098 74 208 2.28E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 SMART SM01086 774 863 1.9E-36 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Gene3D G3DSA:3.40.50.300 558 773 2.8E-53 T 29-03-2018 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 297 309 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 2.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 2.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 2.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 2.0E-42 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 854 6.4E-25 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Gene3D G3DSA:1.10.8.60 774 866 1.3E-24 T 29-03-2018 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 SUPERFAMILY SSF52540 160 551 4.23E-96 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Pfam PF07724 AAA domain (Cdc48 subfamily) 602 768 3.7E-57 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Gene3D G3DSA:1.10.1780.10 1 154 5.0E-35 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 SMART SM00382 201 347 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 SMART SM00382 603 754 1.2E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 SUPERFAMILY SSF52540 552 864 3.74E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 SUPERFAMILY SSF81923 4 158 2.26E-41 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 29-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Gene3D G3DSA:3.40.50.300 160 345 2.7E-25 T 29-03-2018 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 339 1.1E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Gene3D G3DSA:1.10.8.60 346 553 8.9E-45 T 29-03-2018 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 1.8E-16 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS05380 d21388d6223fd6243878233549e6d19c 866 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 148 1.2E-10 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:1.10.8.60 277 348 2.6E-29 T 29-03-2018 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:3.40.50.300 108 275 5.0E-23 T 29-03-2018 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 29-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 29-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 SMART SM00760 355 424 1.9E-41 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 442 1.1E-189 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.187 T 29-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Gene3D G3DSA:1.10.1750.10 349 446 6.1E-35 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 SMART SM00382 143 271 2.4E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Pfam PF11638 DnaA N-terminal domain 6 66 2.6E-20 T 29-03-2018 IPR024633 DnaA N-terminal domain CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Pfam PF00308 Bacterial dnaA protein 111 327 3.0E-108 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 358 424 5.2E-30 T 29-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 SUPERFAMILY SSF48295 342 445 2.51E-36 T 29-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CSW12_RS27310 15a2be9192b61a95d8d355f9e1623895 446 SUPERFAMILY SSF52540 111 323 2.35E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01830 7cafe91fe3d09f7bf188b02a1fb626a9 297 Gene3D G3DSA:3.40.50.300 3 62 1.6E-5 T 29-03-2018 CSW12_RS01830 7cafe91fe3d09f7bf188b02a1fb626a9 297 Gene3D G3DSA:3.40.50.300 63 200 1.0E-25 T 29-03-2018 CSW12_RS01830 7cafe91fe3d09f7bf188b02a1fb626a9 297 SMART SM00382 55 201 1.1E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS01830 7cafe91fe3d09f7bf188b02a1fb626a9 297 Pfam PF07728 AAA domain (dynein-related subfamily) 58 195 1.0E-26 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CSW12_RS01830 7cafe91fe3d09f7bf188b02a1fb626a9 297 SUPERFAMILY SSF52540 46 271 3.2E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 SUPERFAMILY SSF55174 1 59 6.48E-12 T 29-03-2018 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 Pfam PF00849 RNA pseudouridylate synthase 62 195 1.0E-18 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 Pfam PF01479 S4 domain 1 45 3.7E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 2.5E-45 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 SMART SM00363 1 59 4.3E-7 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 Gene3D G3DSA:3.30.70.580 57 142 1.9E-16 T 29-03-2018 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 SUPERFAMILY SSF55120 46 235 6.84E-43 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 Gene3D G3DSA:3.10.290.10 1 56 3.8E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS23215 0426907fe61b8804615531a0d3eaede0 242 Gene3D G3DSA:3.30.70.1560 143 212 9.1E-24 T 29-03-2018 CSW12_RS20475 f242951ab80236f32763f01533923ef1 296 Pfam PF00348 Polyprenyl synthetase 32 268 1.0E-59 T 29-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CSW12_RS20475 f242951ab80236f32763f01533923ef1 296 SUPERFAMILY SSF48576 8 276 3.78E-87 T 29-03-2018 IPR008949 Isoprenoid synthase domain CSW12_RS20475 f242951ab80236f32763f01533923ef1 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CSW12_RS20475 f242951ab80236f32763f01533923ef1 296 Gene3D G3DSA:1.10.600.10 2 296 3.6E-86 T 29-03-2018 IPR008949 Isoprenoid synthase domain CSW12_RS20475 f242951ab80236f32763f01533923ef1 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 29-03-2018 IPR033749 Polyprenyl synthetase, conserved site CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PRINTS PR01466 Bacterial arginine deiminase signature 152 170 6.1E-58 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PRINTS PR01466 Bacterial arginine deiminase signature 389 407 6.1E-58 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PRINTS PR01466 Bacterial arginine deiminase signature 180 195 6.1E-58 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PRINTS PR01466 Bacterial arginine deiminase signature 346 363 6.1E-58 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PRINTS PR01466 Bacterial arginine deiminase signature 366 380 6.1E-58 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 6.1E-58 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 PIRSF PIRSF006356 1 410 1.1E-163 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 TIGRFAM TIGR01078 arcA: arginine deiminase 5 410 2.1E-168 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 Pfam PF02274 Amidinotransferase 19 407 2.5E-113 T 29-03-2018 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 SUPERFAMILY SSF55909 1 410 9.28E-137 T 29-03-2018 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 Gene3D G3DSA:3.75.10.10 4 408 3.8E-100 T 29-03-2018 CSW12_RS00700 02629de220c65c7b28481207157ca155 410 Hamap MF_00242 Arginine deiminase [arcA]. 2 410 48.164 T 29-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CSW12_RS03630 c14b7aecc9b16f2b5bd957bfbfbc5e0e 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS03630 c14b7aecc9b16f2b5bd957bfbfbc5e0e 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 1.1E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS03630 c14b7aecc9b16f2b5bd957bfbfbc5e0e 67 Gene3D G3DSA:3.30.70.250 1 41 0.0012 T 29-03-2018 CSW12_RS03630 c14b7aecc9b16f2b5bd957bfbfbc5e0e 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS21855 65e6247d9676c5236b8a8603944bdd40 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 29-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21855 65e6247d9676c5236b8a8603944bdd40 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 7.4E-40 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21855 65e6247d9676c5236b8a8603944bdd40 102 SUPERFAMILY SSF141091 1 101 9.94E-39 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21855 65e6247d9676c5236b8a8603944bdd40 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.6E-40 T 29-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21855 65e6247d9676c5236b8a8603944bdd40 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.476 T 29-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS20495 7b47d283dfed5d54065c7c5fc3d67f5d 130 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 1 130 23.088 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CSW12_RS20495 7b47d283dfed5d54065c7c5fc3d67f5d 130 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 129 8.2E-46 T 29-03-2018 IPR011605 NusB antitermination factor GO:0006353 CSW12_RS20495 7b47d283dfed5d54065c7c5fc3d67f5d 130 Gene3D G3DSA:1.10.940.10 1 130 1.1E-45 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CSW12_RS20495 7b47d283dfed5d54065c7c5fc3d67f5d 130 Pfam PF01029 NusB family 4 127 1.9E-40 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CSW12_RS20495 7b47d283dfed5d54065c7c5fc3d67f5d 130 SUPERFAMILY SSF48013 3 126 3.66E-40 T 29-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 350 2.1E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SMART SM00387 396 503 1.3E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:3.30.450.20 151 280 2.7E-19 T 29-03-2018 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:3.30.565.10 354 508 4.0E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Pfam PF08448 PAS fold 162 276 3.1E-11 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SMART SM00388 290 354 1.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 280 2.3E-10 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 150 8.8E-17 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SMART SM00091 32 98 1.9E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SMART SM00091 156 221 0.19 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF55785 145 273 1.52E-15 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:1.10.287.130 281 350 2.6E-12 T 29-03-2018 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF47384 283 351 8.04E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 481 3.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 462 3.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 500 3.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 448 3.2E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF55785 17 137 1.08E-15 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Pfam PF13426 PAS domain 42 138 9.7E-9 T 29-03-2018 IPR000014 PAS domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 397 502 1.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 SUPERFAMILY SSF55874 348 501 1.44E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09545 6f907201586388b2131efd474ae59c6b 510 Gene3D G3DSA:3.30.450.20 27 150 2.4E-15 T 29-03-2018 CSW12_RS21305 aed10e9d206afd0eedac7e40f4e81302 368 Pfam PF01926 50S ribosome-binding GTPase 163 237 1.1E-13 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21305 aed10e9d206afd0eedac7e40f4e81302 368 Gene3D G3DSA:3.40.50.300 56 225 2.2E-31 T 29-03-2018 CSW12_RS21305 aed10e9d206afd0eedac7e40f4e81302 368 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 368 3.4E-157 T 29-03-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH CSW12_RS21305 aed10e9d206afd0eedac7e40f4e81302 368 SUPERFAMILY SSF52540 68 281 2.55E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 397 1.0E-8 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.1E-15 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 PIRSF PIRSF004803 1 555 4.8E-249 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 SMART SM00849 21 215 4.9E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 SUPERFAMILY SSF56281 11 423 1.9E-96 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 Gene3D G3DSA:3.60.15.10 3 448 9.6E-65 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 1.2E-232 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CSW12_RS07850 2951399b93b721c4c8cd41e324e694f8 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 48.256 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CSW12_RS27255 16339e6b28f902102959887a044f31af 198 Gene3D G3DSA:3.40.50.1450 9 197 3.5E-32 T 29-03-2018 IPR023430 Peptidase HybD-like domain CSW12_RS27255 16339e6b28f902102959887a044f31af 198 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 44 182 6.1E-70 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CSW12_RS27255 16339e6b28f902102959887a044f31af 198 SUPERFAMILY SSF53163 10 195 1.7E-55 T 29-03-2018 IPR023430 Peptidase HybD-like domain CSW12_RS27255 16339e6b28f902102959887a044f31af 198 Pfam PF06866 Protein of unknown function (DUF1256) 19 180 1.3E-65 T 29-03-2018 IPR009665 Protein of unknown function DUF1256 CSW12_RS21380 395d7ce6d2062665db8bfbffac035907 166 Pfam PF07681 DoxX 16 115 2.0E-10 T 29-03-2018 IPR032808 DoxX family CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 Pfam PF00365 Phosphofructokinase 3 275 2.8E-115 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 SUPERFAMILY SSF53784 1 316 9.55E-121 T 29-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 2.6E-141 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 50.017 T 29-03-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 Gene3D G3DSA:3.40.50.450 1 213 1.2E-86 T 29-03-2018 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 4.1E-90 T 29-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 29-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 Gene3D G3DSA:3.40.50.450 214 309 5.7E-10 T 29-03-2018 CSW12_RS22625 d6a01d071edc45cc2409cf42b058fda4 319 PIRSF PIRSF000532 1 319 1.8E-124 T 29-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CSW12_RS11175 8938ffde2e62ed6abe15daa98df403f4 376 Pfam PF01594 AI-2E family transporter 37 367 3.5E-79 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 168 7.5E-28 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Pfam PF13307 Helicase C-terminal domain 748 913 2.2E-41 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Gene3D G3DSA:3.40.50.300 256 703 9.0E-32 T 29-03-2018 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SMART SM00491 766 900 6.3E-32 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SUPERFAMILY SSF53098 4 273 1.45E-55 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Gene3D G3DSA:3.40.50.300 725 909 1.0E-14 T 29-03-2018 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Gene3D G3DSA:3.30.420.10 1 156 3.4E-38 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SMART SM00479 4 172 1.2E-47 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Pfam PF04851 Type III restriction enzyme, res subunit 257 480 5.3E-6 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SUPERFAMILY SSF52540 408 485 1.48E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SUPERFAMILY SSF52540 722 894 1.48E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SUPERFAMILY SSF52540 273 327 1.48E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SUPERFAMILY SSF52540 675 689 1.48E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Pfam PF00929 Exonuclease 6 163 1.2E-31 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 Gene3D G3DSA:1.20.5.140 157 173 5.0E-6 T 29-03-2018 CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 929 5.8E-266 T 29-03-2018 IPR006310 DnaQ exonuclease/DinG helicase, predicted CSW12_RS19880 f6c3480e404aeed3188ad1712514be41 934 SMART SM00487 255 523 0.006 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS23120 6be659d5ed2f0f13a3d5686ef308f208 372 SUPERFAMILY SSF51690 128 355 1.18E-47 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CSW12_RS23120 6be659d5ed2f0f13a3d5686ef308f208 372 PIRSF PIRSF000484 15 364 2.0E-66 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CSW12_RS23120 6be659d5ed2f0f13a3d5686ef308f208 372 SUPERFAMILY SSF54675 18 128 2.16E-22 T 29-03-2018 CSW12_RS23120 6be659d5ed2f0f13a3d5686ef308f208 372 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 47 118 4.1E-8 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CSW12_RS23120 6be659d5ed2f0f13a3d5686ef308f208 372 Gene3D G3DSA:3.90.1170.20 3 131 1.3E-24 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CSW12_RS23120 6be659d5ed2f0f13a3d5686ef308f208 372 Gene3D G3DSA:3.20.20.70 132 334 1.8E-36 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 Gene3D G3DSA:4.10.320.10 114 161 4.3E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 SUPERFAMILY SSF47005 116 157 9.29E-10 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 Pfam PF00364 Biotin-requiring enzyme 4 76 2.7E-16 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 Gene3D G3DSA:2.40.50.100 2 79 4.3E-19 T 29-03-2018 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 SUPERFAMILY SSF52777 172 399 1.07E-79 T 29-03-2018 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 SUPERFAMILY SSF51230 1 84 1.83E-21 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 Gene3D G3DSA:3.30.559.10 162 399 3.1E-82 T 29-03-2018 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 171 398 1.1E-82 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS13805 a3f459b5396d4b6e3e482ee216d01c1d 399 Pfam PF02817 e3 binding domain 119 154 3.6E-14 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS05540 0b581d1405c0e905c787003877f8d52c 212 SMART SM00954 44 165 3.9E-38 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CSW12_RS05540 0b581d1405c0e905c787003877f8d52c 212 Gene3D G3DSA:1.10.287.860 148 196 5.7E-20 T 29-03-2018 CSW12_RS05540 0b581d1405c0e905c787003877f8d52c 212 Pfam PF04607 Region found in RelA / SpoT proteins 44 162 1.4E-37 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CSW12_RS05540 0b581d1405c0e905c787003877f8d52c 212 SUPERFAMILY SSF81301 4 198 8.99E-60 T 29-03-2018 CSW12_RS05540 0b581d1405c0e905c787003877f8d52c 212 Gene3D G3DSA:3.30.460.10 1 146 1.5E-37 T 29-03-2018 CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 188 4.9E-37 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 Gene3D G3DSA:3.40.50.1000 72 223 6.0E-32 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 Gene3D G3DSA:3.40.50.1000 1 30 0.075 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 SUPERFAMILY SSF56784 1 213 1.73E-42 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 95 186 5.9E-16 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 2.3E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.3E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 2.3E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 104 117 2.3E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS23655 e34d09a76241c1c5577a3b1a80c6bf0c 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 187 3.2E-8 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 Gene3D G3DSA:3.40.50.150 80 283 3.2E-47 T 29-03-2018 CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 3 280 5.5E-78 T 29-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 SUPERFAMILY SSF53335 3 280 9.83E-56 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 282 44.249 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 Gene3D G3DSA:1.10.8.10 1 79 2.8E-15 T 29-03-2018 CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 Pfam PF13847 Methyltransferase domain 112 235 7.5E-16 T 29-03-2018 IPR025714 Methyltransferase domain CSW12_RS26430 7e7363c5a3d4ecce975ffee64499191e 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 278 3.0E-88 T 29-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CSW12_RS25085 fdbe963cd1e4c826e37fc8b79e9c5bed 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 3.6E-21 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS25085 fdbe963cd1e4c826e37fc8b79e9c5bed 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 1.1E-57 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS18770 cbe5f73c53d450fcb165c38e20d30b83 150 SUPERFAMILY SSF54593 4 145 2.48E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS18770 cbe5f73c53d450fcb165c38e20d30b83 150 Gene3D G3DSA:3.10.180.10 1 150 1.7E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS18770 cbe5f73c53d450fcb165c38e20d30b83 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 132 5.9E-8 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF56801 1518 2062 2.22E-152 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3129 3144 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 220 484 1.22E-64 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00668 Condensation domain 2137 2581 1.4E-116 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00668 Condensation domain 3184 3621 2.0E-84 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00668 Condensation domain 31 477 6.9E-120 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00668 Condensation domain 3657 4096 2.1E-92 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00668 Condensation domain 1094 1538 1.9E-117 T 29-03-2018 IPR001242 Condensation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF47336 4616 4687 1.96E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 35 212 2.0E-48 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 3375 3621 3.11E-34 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00550 Phosphopantetheine attachment site 4624 4684 3.7E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00550 Phosphopantetheine attachment site 1008 1070 5.0E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00550 Phosphopantetheine attachment site 2051 2114 7.9E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00550 Phosphopantetheine attachment site 3109 3168 9.3E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3495 3641 1.4E-34 T 29-03-2018 IPR010060 Non-ribosomal peptide synthase CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF56801 4074 4635 9.55E-159 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 1701 1847 1.0E-24 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 2749 2911 8.7E-32 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 4264 4426 2.2E-31 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 644 810 5.7E-40 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.559.10 3172 3374 7.3E-32 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:1.10.1200.10 3109 3171 5.5E-19 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 3188 3364 7.89E-39 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 2592 2748 2.4E-50 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 4107 4263 3.5E-48 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 488 643 8.3E-51 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.980 1550 1700 6.5E-48 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.40.50.1820 4695 4948 4.8E-18 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF56801 2560 3117 3.66E-157 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 4523 4594 8.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 909 980 3.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 3008 3079 2.0E-10 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF13193 AMP-binding enzyme C-terminal domain 1953 2024 4.2E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4257 4268 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 518 925 1.1E-142 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2622 3024 1.0E-132 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4137 4539 5.8E-128 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1580 1969 1.2E-124 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2073 2088 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00975 Thioesterase domain 4709 4932 2.9E-29 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2742 2753 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 638 649 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1030 1045 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 1282 1545 4.0E-63 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 3842 4079 6.23E-52 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF56801 455 1019 1.23E-174 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 2140 2317 4.89E-51 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 3653 3857 9.78E-45 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 2326 2565 6.56E-60 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF47336 1001 1107 6.28E-22 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SMART SM00823 Phosphopantetheine attachment site 2049 2118 4.4E-11 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SMART SM00823 Phosphopantetheine attachment site 1006 1075 1.1E-6 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SMART SM00823 Phosphopantetheine attachment site 3105 3173 0.0097 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1695 1706 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00501 AMP-binding enzyme 2601 3000 2.3E-102 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00501 AMP-binding enzyme 1559 1945 6.6E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00501 AMP-binding enzyme 497 901 3.8E-109 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Pfam PF00501 AMP-binding enzyme 4116 4515 1.4E-99 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF47336 3097 3169 7.33E-17 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:1.10.1200.10 1012 1079 7.9E-23 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:1.10.1200.10 2055 2121 3.5E-25 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.559.10 2122 2339 5.6E-49 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.559.10 1080 1297 6.6E-51 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.559.10 3651 3861 3.4E-38 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.559.10 13 234 6.0E-46 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.300.30 1940 2054 2.0E-38 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.300.30 896 1011 1.7E-38 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.300.30 4510 4628 6.8E-37 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:3.30.300.30 2995 3108 8.8E-38 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:1.10.1200.10 4629 4694 7.6E-18 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF53474 4688 4945 1.12E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:2.30.38.10 4427 4505 9.2E-27 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:2.30.38.10 2912 2990 1.2E-25 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:2.30.38.10 1855 1934 7.4E-22 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 Gene3D G3DSA:2.30.38.10 811 891 3.7E-23 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF52777 1097 1274 8.89E-51 T 29-03-2018 CSW12_RS15525 2a3336eb631fb81855e2838342afc3a4 4960 SUPERFAMILY SSF47336 2043 2150 8.24E-24 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS06620 0b798ae4f13764f306dd8b497e941668 209 Pfam PF00117 Glutamine amidotransferase class-I 4 195 4.8E-21 T 29-03-2018 IPR017926 Glutamine amidotransferase CSW12_RS06620 0b798ae4f13764f306dd8b497e941668 209 PIRSF PIRSF000495 1 201 4.1E-71 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CSW12_RS06620 0b798ae4f13764f306dd8b497e941668 209 SUPERFAMILY SSF52317 2 198 1.53E-55 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS06620 0b798ae4f13764f306dd8b497e941668 209 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 196 8.7E-73 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CSW12_RS06620 0b798ae4f13764f306dd8b497e941668 209 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 198 36.021 T 29-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CSW12_RS06620 0b798ae4f13764f306dd8b497e941668 209 Gene3D G3DSA:3.40.50.880 1 208 2.0E-44 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 Pfam PF02796 Helix-turn-helix domain of resolvase 140 177 2.7E-7 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 Gene3D G3DSA:1.10.10.60 125 180 8.6E-9 T 29-03-2018 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 SUPERFAMILY SSF53041 1 137 2.49E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 Gene3D G3DSA:3.40.50.1390 1 105 1.6E-30 T 29-03-2018 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 SMART SM00857 2 137 1.7E-54 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 SUPERFAMILY SSF46689 140 178 1.67E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 Pfam PF00239 Resolvase, N terminal domain 3 137 1.9E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29070 1fa9a80148af3c4499af9faee438282f 180 Gene3D G3DSA:1.20.5.40 106 124 1.8E-17 T 29-03-2018 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 Pfam PF02796 Helix-turn-helix domain of resolvase 140 177 2.7E-7 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 Gene3D G3DSA:1.10.10.60 125 180 8.6E-9 T 29-03-2018 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 SUPERFAMILY SSF53041 1 137 2.49E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 Gene3D G3DSA:3.40.50.1390 1 105 1.6E-30 T 29-03-2018 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 SMART SM00857 2 137 1.7E-54 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 SUPERFAMILY SSF46689 140 178 1.67E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 Pfam PF00239 Resolvase, N terminal domain 3 137 1.9E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29600 1fa9a80148af3c4499af9faee438282f 180 Gene3D G3DSA:1.20.5.40 106 124 1.8E-17 T 29-03-2018 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:3.30.300.20 272 341 3.5E-17 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF69705 1 126 4.58E-43 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF54814 278 342 6.28E-17 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:3.30.300.20 198 271 2.6E-34 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SMART SM00322 300 368 0.2 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SMART SM00322 229 292 0.22 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 367 30.503 T 29-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SMART SM00316 133 199 9.3E-10 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 8.3E-128 T 29-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:3.30.1480.10 1 128 4.6E-49 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF50249 132 198 1.23E-18 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Pfam PF13184 NusA-like KH domain 229 296 2.6E-26 T 29-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Gene3D G3DSA:2.40.50.140 129 197 3.9E-15 T 29-03-2018 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Pfam PF08529 NusA N-terminal domain 4 123 2.6E-43 T 29-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 Pfam PF00575 S1 RNA binding domain 133 195 1.4E-10 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS08700 9d64e646b252163881f41e877b5ec03f 368 SUPERFAMILY SSF54814 199 277 9.81E-30 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 409 2.5E-99 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Pfam PF02355 Protein export membrane protein 555 733 6.4E-63 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Pfam PF02355 Protein export membrane protein 242 406 1.6E-14 T 29-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 478 724 1.9E-67 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Gene3D G3DSA:1.20.1640.10 200 415 2.2E-27 T 29-03-2018 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Gene3D G3DSA:1.20.1640.10 532 745 1.1E-31 T 29-03-2018 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Pfam PF07549 SecD/SecF GG Motif 471 498 1.3E-7 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Pfam PF07549 SecD/SecF GG Motif 30 51 0.017 T 29-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 560 721 7.3E-48 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 191 402 4.3E-51 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 449 735 25.811 T 29-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 SUPERFAMILY SSF82866 557 737 7.19E-37 T 29-03-2018 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 423 31.273 T 29-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 PRINTS PR01755 Bacterial translocase SecF protein signature 476 491 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 PRINTS PR01755 Bacterial translocase SecF protein signature 672 687 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 PRINTS PR01755 Bacterial translocase SecF protein signature 636 654 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 PRINTS PR01755 Bacterial translocase SecF protein signature 588 602 3.6E-22 T 29-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CSW12_RS21695 317a7b3ca3cd79147b2cc46cbf61b46f 754 SUPERFAMILY SSF82866 212 414 1.83E-38 T 29-03-2018 CSW12_RS03275 a103c075d60a978e10f0f3a7d1cf8f19 400 SUPERFAMILY SSF103473 13 391 1.44E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS03275 a103c075d60a978e10f0f3a7d1cf8f19 400 Gene3D G3DSA:1.20.1250.20 9 201 8.3E-31 T 29-03-2018 CSW12_RS03275 a103c075d60a978e10f0f3a7d1cf8f19 400 Gene3D G3DSA:1.20.1250.20 202 399 1.9E-24 T 29-03-2018 CSW12_RS03275 a103c075d60a978e10f0f3a7d1cf8f19 400 Pfam PF07690 Major Facilitator Superfamily 20 238 1.7E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS03275 a103c075d60a978e10f0f3a7d1cf8f19 400 Pfam PF03209 PUCC protein 276 395 4.2E-5 T 29-03-2018 IPR004896 PucC-related CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 Gene3D G3DSA:1.10.10.10 128 229 4.9E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 Gene3D G3DSA:3.40.50.2300 1 127 1.1E-27 T 29-03-2018 CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 SUPERFAMILY SSF52172 1 123 8.54E-34 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 SMART SM00862 150 225 1.4E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 SMART SM00448 2 112 1.9E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 SUPERFAMILY SSF46894 128 226 8.5E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS21830 27a9cc12dfc1d92333119a33bfbfa30a 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 4.5E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 SUPERFAMILY SSF52540 6 239 1.91E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:2.40.30.10 197 296 1.4E-29 T 29-03-2018 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 SUPERFAMILY SSF54980 408 503 1.25E-27 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 2.3E-53 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 3.1E-52 T 29-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 SUPERFAMILY SSF54980 301 379 1.58E-18 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF03144 Elongation factor Tu domain 2 214 284 1.5E-12 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 183 1.1E-19 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 315.482 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.30.70.870 297 376 3.3E-28 T 29-03-2018 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Pfam PF00679 Elongation factor G C-terminus 408 495 1.9E-25 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 SMART SM00838 410 495 1.4E-4 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 29-03-2018 IPR006297 Elongation factor 4 GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.8E-14 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.30.70.240 399 559 4.5E-32 T 29-03-2018 CSW12_RS21215 c22ab38158e808d5a6ebb8259546cb6c 607 Gene3D G3DSA:3.40.50.300 1 196 1.3E-36 T 29-03-2018 CSW12_RS09855 b24c9928785905f30117bf3caec24abc 1120 Pfam PF13809 Tubulin like 8 345 5.1E-74 T 29-03-2018 IPR025904 Tubulin-like CSW12_RS09855 b24c9928785905f30117bf3caec24abc 1120 Gene3D G3DSA:3.40.50.1440 5 311 1.7E-20 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS09855 b24c9928785905f30117bf3caec24abc 1120 SUPERFAMILY SSF52490 120 166 2.62E-7 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS09855 b24c9928785905f30117bf3caec24abc 1120 SUPERFAMILY SSF52490 5 78 2.62E-7 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS01525 6b31af4bbb490b1eab7fc10ca8a0b35a 167 SUPERFAMILY SSF160387 50 159 1.12E-28 T 29-03-2018 CSW12_RS01525 6b31af4bbb490b1eab7fc10ca8a0b35a 167 Pfam PF05573 NosL 18 145 3.7E-20 T 29-03-2018 IPR008719 Nitrous oxide reductase accessory protein NosL CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 Gene3D G3DSA:3.40.50.300 24 266 2.1E-14 T 29-03-2018 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 Hamap MF_00900 GTPase HflX [hflX]. 25 391 45.65 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 SUPERFAMILY SSF52540 198 372 2.7E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 Gene3D G3DSA:1.20.120.430 270 407 7.2E-12 T 29-03-2018 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 Pfam PF01926 50S ribosome-binding GTPase 200 325 8.7E-18 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 Pfam PF16360 GTP-binding GTPase Middle Region 112 192 3.0E-26 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 PIRSF PIRSF006809 1 418 2.2E-146 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 1.7E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 274 292 1.7E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 Pfam PF13167 GTP-binding GTPase N-terminal 23 110 6.4E-35 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CSW12_RS18705 2858fc1d22dcd9840240db3f659d3fd0 419 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 7 360 6.3E-140 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 PIRSF PIRSF005900 1 146 1.1E-51 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 Pfam PF00210 Ferritin-like domain 6 146 2.5E-36 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 Gene3D G3DSA:1.20.1260.10 1 146 2.0E-53 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 7.5E-17 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 7.5E-17 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 7.5E-17 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS25050 f0c596103c8c48ac6f739409868bc768 146 SUPERFAMILY SSF47240 3 144 3.21E-50 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 456 57.272 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 Gene3D G3DSA:3.40.1060.10 154 285 2.2E-41 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 118 131 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 132 147 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 333 344 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 107 115 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 208 221 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 389 402 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 81 94 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 283 297 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 PRINTS PR00415 Aconitase family signature 194 207 4.6E-45 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 Gene3D G3DSA:3.30.499.10 296 461 2.5E-51 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 454 6.7E-214 T 29-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 Gene3D G3DSA:3.30.499.10 1 153 2.6E-40 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 SUPERFAMILY SSF53732 2 454 6.02E-162 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 ProSitePatterns PS01244 Aconitase family signature 2. 389 402 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 ProSitePatterns PS00450 Aconitase family signature 1. 329 345 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CSW12_RS06590 9cc19f8df6833a2ab6fe896114686f7b 464 Pfam PF00330 Aconitase family (aconitate hydratase) 7 447 2.7E-153 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS16440 50f77f21843bf5ceb2b43b469147a197 273 SMART SM00219 24 254 0.0026 T 29-03-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 CSW12_RS16440 50f77f21843bf5ceb2b43b469147a197 273 Gene3D G3DSA:1.10.510.10 92 272 1.3E-25 T 29-03-2018 CSW12_RS16440 50f77f21843bf5ceb2b43b469147a197 273 Gene3D G3DSA:3.30.200.20 13 91 1.4E-16 T 29-03-2018 CSW12_RS16440 50f77f21843bf5ceb2b43b469147a197 273 SUPERFAMILY SSF56112 20 243 4.72E-43 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS16440 50f77f21843bf5ceb2b43b469147a197 273 Pfam PF00069 Protein kinase domain 24 209 3.4E-28 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS14430 3153d90941690dfa5d2ee955147487c7 199 Gene3D G3DSA:1.20.144.10 7 184 1.6E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS14430 3153d90941690dfa5d2ee955147487c7 199 SMART SM00014 57 165 2.0E-14 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS14430 3153d90941690dfa5d2ee955147487c7 199 Pfam PF01569 PAP2 superfamily 59 167 2.0E-18 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS14430 3153d90941690dfa5d2ee955147487c7 199 SUPERFAMILY SSF48317 4 193 1.13E-37 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS10260 75aa1b7df90163b8c13bd5c45197f617 319 Gene3D G3DSA:3.90.25.10 179 317 4.0E-28 T 29-03-2018 CSW12_RS10260 75aa1b7df90163b8c13bd5c45197f617 319 SUPERFAMILY SSF51735 2 316 1.69E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10260 75aa1b7df90163b8c13bd5c45197f617 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 240 2.2E-48 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS10260 75aa1b7df90163b8c13bd5c45197f617 319 Gene3D G3DSA:3.40.50.720 2 178 6.1E-37 T 29-03-2018 CSW12_RS23340 40086c1db341f44d0c4f551b190b1a55 101 Pfam PF00581 Rhodanese-like domain 8 97 9.7E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS23340 40086c1db341f44d0c4f551b190b1a55 101 SUPERFAMILY SSF52821 3 97 1.17E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS23340 40086c1db341f44d0c4f551b190b1a55 101 Gene3D G3DSA:3.40.250.10 1 101 9.9E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS23340 40086c1db341f44d0c4f551b190b1a55 101 SMART SM00450 7 101 5.6E-12 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS13545 3192b94ca6c298c606204f640926757e 167 SUPERFAMILY SSF55729 13 166 6.06E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13545 3192b94ca6c298c606204f640926757e 167 Pfam PF00583 Acetyltransferase (GNAT) family 46 139 6.4E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13545 3192b94ca6c298c606204f640926757e 167 Gene3D G3DSA:3.40.630.30 3 167 1.6E-27 T 29-03-2018 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 SUPERFAMILY SSF52172 14 139 3.98E-32 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 Gene3D G3DSA:1.10.10.10 162 272 1.4E-54 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 PIRSF PIRSF002937 11 276 1.6E-132 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 SMART SM00448 16 131 2.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 Pfam PF00072 Response regulator receiver domain 18 131 3.9E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 166 269 1.3E-45 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 165 275 2.0E-59 T 29-03-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 14 276 1.4E-137 T 29-03-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 Gene3D G3DSA:3.40.50.2300 15 154 9.4E-32 T 29-03-2018 CSW12_RS20440 779af38a8b7829d4ccd5367cbffe55a9 276 SUPERFAMILY SSF46894 160 274 1.19E-48 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS26770 1264c56d640e91d40931ddafaeeb423b 97 Pfam PF12823 Domain of unknown function (DUF3817) 7 93 8.3E-21 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CSW12_RS26770 1264c56d640e91d40931ddafaeeb423b 97 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 10 92 1.4E-26 T 29-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 Gene3D G3DSA:1.10.10.10 67 162 9.9E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 SUPERFAMILY SSF88946 2 74 8.37E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 155 5.1E-26 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 SUPERFAMILY SSF88659 89 157 5.98E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 Gene3D G3DSA:1.10.1740.10 1 66 6.4E-16 T 29-03-2018 CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 Pfam PF04542 Sigma-70 region 2 2 68 9.3E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18865 754f78d7df6868b270b49704044f7ed2 162 Pfam PF08281 Sigma-70, region 4 101 151 9.7E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18355 94c165d9ba14ff0ff2c3831331d2ac21 131 SUPERFAMILY SSF53927 2 130 1.42E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS18355 94c165d9ba14ff0ff2c3831331d2ac21 131 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CSW12_RS18355 94c165d9ba14ff0ff2c3831331d2ac21 131 Gene3D G3DSA:3.40.140.10 1 131 7.0E-52 T 29-03-2018 CSW12_RS18355 94c165d9ba14ff0ff2c3831331d2ac21 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 4.7E-48 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CSW12_RS18355 94c165d9ba14ff0ff2c3831331d2ac21 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 102 1.8E-19 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CSW12_RS05560 bcf176ca212397072766a7dd48fd0270 246 Gene3D G3DSA:3.60.21.10 1 242 2.8E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS05560 bcf176ca212397072766a7dd48fd0270 246 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 246 63.41 T 29-03-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 CSW12_RS05560 bcf176ca212397072766a7dd48fd0270 246 SUPERFAMILY SSF56300 1 220 3.47E-41 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS05560 bcf176ca212397072766a7dd48fd0270 246 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 1.0E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 Gene3D G3DSA:3.40.50.300 319 576 1.7E-72 T 29-03-2018 CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 SMART SM00382 361 547 1.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 Gene3D G3DSA:1.20.1560.10 1 316 2.3E-73 T 29-03-2018 CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 Pfam PF00005 ABC transporter 352 501 1.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 Pfam PF00664 ABC transporter transmembrane region 19 289 3.5E-45 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 SUPERFAMILY SSF52540 327 571 6.46E-84 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS15870 cbb1e742b237252094d0f21d8ec40272 584 SUPERFAMILY SSF90123 5 318 1.44E-72 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 Gene3D G3DSA:3.30.70.260 254 336 4.4E-20 T 29-03-2018 CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 Pfam PF00005 ABC transporter 21 169 6.9E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 SMART SM00930 260 335 5.2E-23 T 29-03-2018 IPR018449 NIL domain CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 Gene3D G3DSA:3.40.50.300 1 253 2.2E-76 T 29-03-2018 CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 SUPERFAMILY SSF52540 1 240 7.83E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 SMART SM00382 30 218 9.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 SUPERFAMILY SSF55021 248 333 2.4E-18 T 29-03-2018 CSW12_RS28325 d5da55c520f5143ecbfb96d118a4c39f 346 Pfam PF09383 NIL domain 263 333 1.7E-17 T 29-03-2018 IPR018449 NIL domain CSW12_RS13935 340645bd69add2c1995016c84f0fa10a 110 Pfam PF13028 Protein of unknown function (DUF3889) 22 106 1.1E-30 T 29-03-2018 IPR024987 Protein of unknown function DUF3889 CSW12_RS03350 f341988ad52c1bba9e0f5be040b43859 334 SUPERFAMILY SSF161098 75 265 3.27E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03350 f341988ad52c1bba9e0f5be040b43859 334 Gene3D G3DSA:1.10.3720.10 4 295 2.5E-25 T 29-03-2018 CSW12_RS03350 f341988ad52c1bba9e0f5be040b43859 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 237 1.6E-7 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS25775 dfe6bc600a840ba5e9c201f2dc385def 435 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 420 1.9E-141 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CSW12_RS25775 dfe6bc600a840ba5e9c201f2dc385def 435 Pfam PF02378 Phosphotransferase system, EIIC 29 349 3.5E-64 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS25775 dfe6bc600a840ba5e9c201f2dc385def 435 PIRSF PIRSF006351 1 432 1.5E-147 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS25775 dfe6bc600a840ba5e9c201f2dc385def 435 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 420 1.9E-141 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS17700 411950c41e6b39f3b800879223c7b180 203 SMART SM00855 4 158 1.7E-19 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS17700 411950c41e6b39f3b800879223c7b180 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 7 16 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CSW12_RS17700 411950c41e6b39f3b800879223c7b180 203 PIRSF PIRSF000709 1 175 2.2E-24 T 29-03-2018 CSW12_RS17700 411950c41e6b39f3b800879223c7b180 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 198 8.8E-60 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS17700 411950c41e6b39f3b800879223c7b180 203 Gene3D G3DSA:3.40.50.1240 2 203 1.3E-56 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS17700 411950c41e6b39f3b800879223c7b180 203 SUPERFAMILY SSF53254 1 202 5.11E-60 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS05845 bc6295c34b44af94ecbe93b70791e029 76 SMART SM00530 4 59 2.6E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05845 bc6295c34b44af94ecbe93b70791e029 76 Pfam PF01381 Helix-turn-helix 7 57 2.0E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05845 bc6295c34b44af94ecbe93b70791e029 76 Gene3D G3DSA:1.10.10.10 3 23 6.3E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS05845 bc6295c34b44af94ecbe93b70791e029 76 SUPERFAMILY SSF47413 2 63 4.56E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS05845 bc6295c34b44af94ecbe93b70791e029 76 Gene3D G3DSA:3.30.1190.10 24 74 1.8E-13 T 29-03-2018 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 SUPERFAMILY SSF52518 368 561 1.14E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 333 4.2E-41 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 539 1.6E-48 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 Gene3D G3DSA:3.40.50.970 3 194 1.1E-61 T 29-03-2018 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 SUPERFAMILY SSF52467 191 359 3.85E-58 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 11 561 3.3E-253 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 Gene3D G3DSA:3.40.50.970 352 559 2.6E-48 T 29-03-2018 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 Gene3D G3DSA:3.40.50.1220 195 351 1.2E-47 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 173 3.0E-58 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 SUPERFAMILY SSF52518 4 183 3.77E-62 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS06565 a8160cca1a2168c37a03a171a76ff51c 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 29-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 4.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 SUPERFAMILY SSF46689 14 78 1.55E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 Pfam PF14278 Transcriptional regulator C-terminal region 105 181 2.8E-21 T 29-03-2018 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 8.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 8.1E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 Gene3D G3DSA:1.10.10.60 58 187 7.9E-5 T 29-03-2018 CSW12_RS12215 290c46317cd25e26fc0829ffe1357519 211 Gene3D G3DSA:1.10.10.60 17 57 2.7E-14 T 29-03-2018 CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 Gene3D G3DSA:3.30.1330.30 2 95 8.9E-23 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 Gene3D G3DSA:3.40.1280.10 96 252 1.0E-41 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 SUPERFAMILY SSF75217 105 248 1.88E-43 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 Pfam PF00588 SpoU rRNA Methylase family 108 245 1.2E-37 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 3.0E-11 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 SUPERFAMILY SSF55315 3 96 1.04E-24 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS22425 60c7d5aebdbcd1f409fea76c7c892298 254 SMART SM00967 31 99 3.8E-9 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 Gene3D G3DSA:3.40.190.10 159 259 1.0E-15 T 29-03-2018 CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 SMART SM00079 35 257 5.9E-5 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 256 1.7E-58 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 SUPERFAMILY SSF53850 1 257 3.11E-65 T 29-03-2018 CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 Gene3D G3DSA:3.40.190.10 31 158 6.8E-39 T 29-03-2018 CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 SMART SM00062 35 258 1.4E-68 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS20335 92d22842194b76b0f79f9b8d422dd557 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.2E-44 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 SUPERFAMILY SSF69742 2 158 8.89E-45 T 29-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 SUPERFAMILY SSF69075 317 420 3.53E-16 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 PIRSF PIRSF000445 1 434 2.2E-149 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 29-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 1.7E-145 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 321 419 5.4E-19 T 29-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 3.6E-44 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 Gene3D G3DSA:3.40.50.720 158 320 5.5E-22 T 29-03-2018 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 SUPERFAMILY SSF51735 163 314 1.08E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 420 28.945 T 29-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CSW12_RS21965 a0b25034c724bf9882b5b84195ede415 444 Gene3D G3DSA:1.10.1200.70 332 420 6.8E-19 T 29-03-2018 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 Gene3D G3DSA:2.40.10.10 179 290 1.7E-34 T 29-03-2018 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 Gene3D G3DSA:2.30.42.10 291 391 9.6E-21 T 29-03-2018 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 PRINTS PR00834 HtrA/DegQ protease family signature 178 202 7.0E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 7.0E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 7.0E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 7.0E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 PRINTS PR00834 HtrA/DegQ protease family signature 335 347 7.0E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 7.0E-36 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 Gene3D G3DSA:2.40.10.10 67 178 1.1E-29 T 29-03-2018 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 Pfam PF13365 Trypsin-like peptidase domain 104 251 2.7E-30 T 29-03-2018 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 SMART SM00228 289 377 1.3E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 SUPERFAMILY SSF50494 69 286 6.59E-56 T 29-03-2018 IPR009003 Peptidase S1, PA clan CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 Pfam PF13180 PDZ domain 289 386 3.7E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS27150 3362fdc3adf067e28e2ba83e11abfba7 391 SUPERFAMILY SSF50156 271 386 1.58E-20 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.8.60 345 488 4.7E-45 T 29-03-2018 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 SUPERFAMILY SSF52540 162 470 6.91E-78 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 SUPERFAMILY SSF81923 5 150 6.75E-33 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 793 1.5E-27 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 605 7.2E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 663 7.2E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 7.2E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 616 634 7.2E-43 T 29-03-2018 IPR001270 ClpA/B family GO:0005524 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 572 590 - T 29-03-2018 IPR028299 ClpA/B, conserved site 2 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 29-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.1780.10 1 76 1.4E-23 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:3.40.50.300 493 714 2.1E-56 T 29-03-2018 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.1780.10 77 192 3.3E-28 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 SMART SM00382 201 345 4.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 SMART SM00382 538 678 7.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF02151 UvrB/uvrC motif 419 452 3.9E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 537 709 1.6E-58 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:1.10.8.60 715 810 2.3E-26 T 29-03-2018 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 SUPERFAMILY SSF52540 487 804 1.8E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 69 4.4E-15 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 29-03-2018 IPR004176 Clp, N-terminal GO:0019538 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Gene3D G3DSA:3.40.50.300 193 343 6.8E-20 T 29-03-2018 CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 SMART SM01086 715 804 5.2E-39 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS27835 27dce9a0ddc806a648f863a3ce998893 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 318 1.8E-13 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 Pfam PF07702 UTRA domain 92 225 1.1E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 SMART SM00866 90 227 1.3E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 SUPERFAMILY SSF46785 4 71 1.92E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08990 383975c40fdc342924929de7df918f47 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.4E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 Gene3D G3DSA:3.40.1410.10 75 233 4.8E-34 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS08990 383975c40fdc342924929de7df918f47 235 SMART SM00345 8 67 5.8E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.5E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08990 383975c40fdc342924929de7df918f47 235 SUPERFAMILY SSF64288 77 229 5.34E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS08990 383975c40fdc342924929de7df918f47 235 Gene3D G3DSA:1.10.10.10 1 74 1.7E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24260 baa3968521f1748b9bc017f8d48b08c1 226 Pfam PF02308 MgtC family 10 134 5.7E-33 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS24260 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 66 88 3.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS24260 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS24260 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 94 118 3.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS24260 baa3968521f1748b9bc017f8d48b08c1 226 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.0E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 SUPERFAMILY SSF56059 83 352 1.22E-65 T 29-03-2018 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.4E-45 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 SMART SM00878 336 439 6.0E-52 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 2.2E-75 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 Gene3D G3DSA:3.40.50.20 1 118 3.7E-55 T 29-03-2018 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 Gene3D G3DSA:3.30.470.20 205 442 7.5E-100 T 29-03-2018 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 SUPERFAMILY SSF51246 331 440 1.57E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 SUPERFAMILY SSF52440 1 113 3.17E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 Pfam PF02785 Biotin carboxylase C-terminal domain 336 439 2.1E-34 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS15030 b1cab99dc1c7d3c86f0b705edf60a88f 445 Gene3D G3DSA:3.30.1490.20 119 204 1.5E-18 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 Gene3D G3DSA:1.10.10.10 125 223 8.9E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 Gene3D G3DSA:3.40.50.2300 1 124 2.8E-37 T 29-03-2018 CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 4.6E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 SMART SM00448 1 111 7.8E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 SMART SM00862 148 221 8.7E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 Pfam PF00072 Response regulator receiver domain 3 111 7.1E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26075 9266f1283a555d5df79757d4d5341e1c 223 SUPERFAMILY SSF52172 1 175 5.12E-41 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 Gene3D G3DSA:3.20.20.70 5 120 2.2E-14 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 PIRSF PIRSF000368 1 150 3.0E-55 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 Pfam PF04055 Radical SAM superfamily 20 108 5.0E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 SUPERFAMILY SSF102114 22 101 8.37E-12 T 29-03-2018 CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 149 5.0E-50 T 29-03-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 CSW12_RS09735 6d73c726e8a564b036b07bcf4be15819 150 Pfam PF13353 4Fe-4S single cluster domain 12 146 3.6E-37 T 29-03-2018 CSW12_RS03450 d1e344b2c99744eb08137e47b4d495d4 287 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 77 1.3E-15 T 29-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CSW12_RS03450 d1e344b2c99744eb08137e47b4d495d4 287 Gene3D G3DSA:1.10.10.10 1 83 1.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03450 d1e344b2c99744eb08137e47b4d495d4 287 SUPERFAMILY SSF53697 98 269 5.11E-42 T 29-03-2018 CSW12_RS03450 d1e344b2c99744eb08137e47b4d495d4 287 SUPERFAMILY SSF46689 5 77 4.66E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS03450 d1e344b2c99744eb08137e47b4d495d4 287 Pfam PF01380 SIS domain 130 259 2.0E-22 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CSW12_RS03450 d1e344b2c99744eb08137e47b4d495d4 287 Gene3D G3DSA:3.40.50.10490 86 286 6.4E-39 T 29-03-2018 CSW12_RS10445 540ea491d554974454b88233949b13e1 375 Pfam PF00144 Beta-lactamase 76 359 4.1E-56 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS10445 540ea491d554974454b88233949b13e1 375 Gene3D G3DSA:3.40.710.10 39 375 1.3E-71 T 29-03-2018 CSW12_RS10445 540ea491d554974454b88233949b13e1 375 SUPERFAMILY SSF56601 56 360 9.66E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS00960 4f2cc7299df3308daa6369a883666ec1 316 Pfam PF00892 EamA-like transporter family 167 301 2.6E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS00960 4f2cc7299df3308daa6369a883666ec1 316 Pfam PF00892 EamA-like transporter family 15 154 1.8E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS00960 4f2cc7299df3308daa6369a883666ec1 316 SUPERFAMILY SSF103481 54 157 9.29E-13 T 29-03-2018 CSW12_RS00960 4f2cc7299df3308daa6369a883666ec1 316 SUPERFAMILY SSF103481 210 305 1.96E-11 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:3.30.470.30 120 236 7.2E-50 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SUPERFAMILY SSF52113 594 667 1.13E-19 T 29-03-2018 IPR001357 BRCT domain CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:1.10.150.20 502 572 2.7E-24 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 663 2.7E-269 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SMART SM00292 593 669 1.6E-14 T 29-03-2018 IPR001357 BRCT domain CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SMART SM00278 476 495 0.98 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SMART SM00278 540 559 3.8 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SMART SM00278 442 461 120.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SUPERFAMILY SSF50249 314 396 6.85E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 404 430 5.0E-10 T 29-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:3.30.1490.70 237 318 5.0E-32 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:3.40.50.10190 614 669 1.1E-17 T 29-03-2018 IPR001357 BRCT domain CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 PIRSF PIRSF001604 1 669 1.7E-260 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SMART SM00532 5 444 1.3E-275 T 29-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Hamap MF_01588 DNA ligase [ligA]. 4 667 53.174 T 29-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Pfam PF12826 Helix-hairpin-helix motif 506 568 1.5E-24 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 665 2.5E-14 T 29-03-2018 IPR001357 BRCT domain CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 328 343 - T 29-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:1.10.150.20 573 613 0.33 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SUPERFAMILY SSF47781 401 581 4.82E-66 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 319 395 7.9E-34 T 29-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:2.40.50.140 319 387 2.1E-31 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:1.10.287.610 1 69 2.9E-22 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Pfam PF14520 Helix-hairpin-helix domain 444 496 1.5E-6 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 SUPERFAMILY SSF56091 4 313 1.31E-121 T 29-03-2018 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 6 315 1.2E-128 T 29-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 116 145 - T 29-03-2018 IPR018239 NAD-dependent DNA ligase, active site CSW12_RS00115 30d04007cc45f5ee33ae583f5257b9cb 669 Gene3D G3DSA:1.10.150.20 428 501 5.6E-30 T 29-03-2018 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1058 1230 2.7E-10 T 29-03-2018 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 13 1238 0.0 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 465 2.1E-82 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Pfam PF13361 UvrD-like helicase C-terminal domain 476 889 3.0E-30 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 11 1239 20.115 T 29-03-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Gene3D G3DSA:3.90.320.10 1011 1239 3.3E-43 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 SUPERFAMILY SSF52980 1018 1233 3.59E-39 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 SUPERFAMILY SSF52540 556 825 1.9E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 SUPERFAMILY SSF52540 7 188 1.9E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 SUPERFAMILY SSF52540 346 505 1.9E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 SUPERFAMILY SSF52540 867 894 1.9E-116 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Gene3D G3DSA:1.10.486.10 624 779 8.2E-40 T 29-03-2018 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Gene3D G3DSA:3.40.50.300 479 623 1.4E-23 T 29-03-2018 CSW12_RS04970 554322e8440f72f828f03d5e2e157e54 1241 Gene3D G3DSA:3.40.50.300 7 478 5.2E-55 T 29-03-2018 CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0082 T 29-03-2018 CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.4E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.4E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.4E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 SUPERFAMILY SSF51735 6 244 2.4E-88 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 244 6.3E-91 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 Gene3D G3DSA:3.40.50.720 46 246 5.3E-68 T 29-03-2018 CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 Gene3D G3DSA:3.40.50.720 2 45 6.7E-11 T 29-03-2018 CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 1.1E-73 T 29-03-2018 CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.3E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS09985 d010ef834c7f65606108f78472ebcb86 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS16185 81dd6c04cf4db1cf4fb2149937a144dc 399 SUPERFAMILY SSF56322 17 391 7.59E-98 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS16185 81dd6c04cf4db1cf4fb2149937a144dc 399 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 101 389 1.4E-92 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CSW12_RS16185 81dd6c04cf4db1cf4fb2149937a144dc 399 Gene3D G3DSA:3.60.120.10 2 392 2.1E-105 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS16185 81dd6c04cf4db1cf4fb2149937a144dc 399 Pfam PF00425 chorismate binding enzyme 122 381 1.9E-81 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CSW12_RS19125 59137a95c93978022b938168c51f556a 556 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 552 5.9E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS19125 59137a95c93978022b938168c51f556a 556 SUPERFAMILY SSF161098 294 551 5.33E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS19125 59137a95c93978022b938168c51f556a 556 SUPERFAMILY SSF161098 11 271 8.13E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS19125 59137a95c93978022b938168c51f556a 556 Gene3D G3DSA:1.10.3720.10 10 276 7.6E-24 T 29-03-2018 CSW12_RS19125 59137a95c93978022b938168c51f556a 556 Gene3D G3DSA:1.10.3720.10 294 555 2.0E-32 T 29-03-2018 CSW12_RS21905 7fbf7c2519e8431ca48f2379c69fb38a 191 Pfam PF02545 Maf-like protein 3 183 3.2E-61 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CSW12_RS21905 7fbf7c2519e8431ca48f2379c69fb38a 191 Hamap MF_00528 Septum formation protein Maf [maf]. 3 188 33.459 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CSW12_RS21905 7fbf7c2519e8431ca48f2379c69fb38a 191 PIRSF PIRSF006305 1 190 1.6E-64 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CSW12_RS21905 7fbf7c2519e8431ca48f2379c69fb38a 191 Gene3D G3DSA:3.90.950.10 1 188 2.3E-73 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CSW12_RS21905 7fbf7c2519e8431ca48f2379c69fb38a 191 SUPERFAMILY SSF52972 2 183 2.29E-63 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CSW12_RS21905 7fbf7c2519e8431ca48f2379c69fb38a 191 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 182 6.6E-66 T 29-03-2018 IPR003697 Maf-like protein GO:0047429 CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 2.3E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 Gene3D G3DSA:1.10.10.10 130 232 5.4E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 SMART SM00448 4 114 3.7E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 SMART SM00862 154 230 2.6E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 Gene3D G3DSA:3.40.50.2300 3 129 9.4E-39 T 29-03-2018 CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 Pfam PF00072 Response regulator receiver domain 6 115 7.9E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23985 beaf0911f1afa35de35028e133ca09ff 232 SUPERFAMILY SSF52172 1 189 3.13E-44 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 514 2.9E-249 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 Gene3D G3DSA:3.40.309.10 302 490 1.0E-62 T 29-03-2018 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 74.357 T 29-03-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 Gene3D G3DSA:3.40.605.10 25 301 2.6E-82 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 SUPERFAMILY SSF53720 4 511 5.5E-154 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS00130 235f9da42ed2699883be2558c3dcc968 515 Pfam PF00171 Aldehyde dehydrogenase family 50 510 4.2E-154 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 SUPERFAMILY SSF52540 1097 1250 1.2E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 Gene3D G3DSA:3.40.50.300 276 700 1.4E-24 T 29-03-2018 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 Gene3D G3DSA:3.40.50.300 1033 1257 3.9E-5 T 29-03-2018 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 Gene3D G3DSA:3.40.50.300 758 1008 2.5E-10 T 29-03-2018 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 SMART SM00382 829 1278 1.8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 SMART SM00382 492 673 0.4 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 9 1313 0.0 T 29-03-2018 IPR023839 Firmicutes EssC, C-terminal CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 Pfam PF01580 FtsK/SpoIIIE family 1103 1252 5.6E-16 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 Pfam PF01580 FtsK/SpoIIIE family 486 676 4.5E-29 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 Pfam PF01580 FtsK/SpoIIIE family 807 1001 1.1E-24 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 SUPERFAMILY SSF52540 454 711 8.6E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17015 bfbc33395aedfc1e8005c7fb466be5da 1342 SUPERFAMILY SSF52540 773 1016 1.5E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22240 66ccc7e33bc725c0e3fc21aaf4cd549b 678 Gene3D G3DSA:1.10.3470.10 350 678 2.4E-64 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS22240 66ccc7e33bc725c0e3fc21aaf4cd549b 678 Gene3D G3DSA:1.10.3470.10 5 337 5.8E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS22240 66ccc7e33bc725c0e3fc21aaf4cd549b 678 SUPERFAMILY SSF81345 351 672 1.96E-79 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS22240 66ccc7e33bc725c0e3fc21aaf4cd549b 678 SUPERFAMILY SSF81345 5 329 7.98E-72 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS22240 66ccc7e33bc725c0e3fc21aaf4cd549b 678 Pfam PF01032 FecCD transport family 20 329 7.4E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS22240 66ccc7e33bc725c0e3fc21aaf4cd549b 678 Pfam PF01032 FecCD transport family 364 672 4.6E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 1.0E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 1.0E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 1.0E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.0E-11 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 77 181 3.1E-13 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 60 179 2.0E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 Gene3D G3DSA:1.10.150.240 30 71 1.8E-16 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 1 214 48.341 T 29-03-2018 IPR023733 Pyrophosphatase PpaX GO:0008152|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 Gene3D G3DSA:3.40.50.1000 1 29 0.052 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 SUPERFAMILY SSF56784 1 213 4.8E-59 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 2.4E-56 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 53 175 3.6E-14 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS25500 8dba5972691b35ff853e8ad0aca2c956 216 Gene3D G3DSA:3.40.50.1000 72 216 1.0E-34 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS10285 012e7b94c8a187dda2aef80a69778959 367 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 356 8.8E-62 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS10285 012e7b94c8a187dda2aef80a69778959 367 Pfam PF03845 Spore germination protein 8 322 5.6E-57 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS04455 19d031cac56d67625f641416f352366e 186 PIRSF PIRSF016897 1 186 1.6E-64 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CSW12_RS04455 19d031cac56d67625f641416f352366e 186 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 1.7E-62 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CSW12_RS04455 19d031cac56d67625f641416f352366e 186 SUPERFAMILY SSF110391 8 181 1.31E-62 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CSW12_RS04455 19d031cac56d67625f641416f352366e 186 Gene3D G3DSA:3.20.20.400 1 181 3.9E-70 T 29-03-2018 CSW12_RS19920 bba30b80eee062cdecd4ff24b583408e 381 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 373 4.5E-181 T 29-03-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 CSW12_RS19920 bba30b80eee062cdecd4ff24b583408e 381 Pfam PF00534 Glycosyl transferases group 1 188 350 1.1E-42 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS19920 bba30b80eee062cdecd4ff24b583408e 381 Gene3D G3DSA:3.40.50.2000 1 188 3.9E-18 T 29-03-2018 CSW12_RS19920 bba30b80eee062cdecd4ff24b583408e 381 Pfam PF13439 Glycosyltransferase Family 4 13 177 6.2E-25 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CSW12_RS19920 bba30b80eee062cdecd4ff24b583408e 381 SUPERFAMILY SSF53756 8 375 8.17E-92 T 29-03-2018 CSW12_RS19920 bba30b80eee062cdecd4ff24b583408e 381 Gene3D G3DSA:3.40.50.2000 189 356 1.4E-47 T 29-03-2018 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 SMART SM00936 306 408 1.1E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 SUPERFAMILY SSF56601 4 306 3.03E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 SUPERFAMILY SSF69189 298 387 1.71E-17 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 1.5E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 1.5E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 1.5E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 306 408 1.9E-16 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 285 7.0E-83 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 Gene3D G3DSA:2.60.410.10 308 408 4.7E-16 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS27375 8178ee4fd7346c36bd9456f8cf3641ed 438 Gene3D G3DSA:3.40.710.10 28 306 8.2E-50 T 29-03-2018 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 Gene3D G3DSA:3.40.640.10 170 314 5.7E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 Gene3D G3DSA:3.90.1150.10 1 166 1.8E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 Pfam PF00202 Aminotransferase class-III 35 394 3.2E-76 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 SUPERFAMILY SSF53383 4 426 1.79E-131 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 Gene3D G3DSA:3.90.1150.10 315 428 1.3E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 106.59 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CSW12_RS21940 295a3a9c3b2107309b51bf877191fe24 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 425 3.0E-200 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 SUPERFAMILY SSF55874 258 405 8.25E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 405 4.3E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 SMART SM00387 302 406 1.2E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 Gene3D G3DSA:3.30.565.10 220 406 4.9E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 366 2.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 385 2.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 352 2.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23600 840ff5bc0d182e91d8bc411a672cdec7 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 404 2.5E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 SUPERFAMILY SSF52540 309 507 5.79E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 Pfam PF00005 ABC transporter 338 464 4.7E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 Pfam PF00005 ABC transporter 21 189 4.0E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 SMART SM00382 28 233 1.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 SMART SM00382 345 509 5.5E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 Pfam PF12848 ABC transporter 228 302 4.0E-20 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 Gene3D G3DSA:3.40.50.300 288 512 3.4E-45 T 29-03-2018 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 Gene3D G3DSA:3.40.50.300 4 287 1.7E-50 T 29-03-2018 CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 SUPERFAMILY SSF52540 130 254 7.03E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00815 d3f79069372db8b3a7c77ec3456d433c 514 SUPERFAMILY SSF52540 3 94 7.03E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 5.1E-141 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 6.5E-43 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 SUPERFAMILY SSF51735 3 167 1.28E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 Gene3D G3DSA:3.30.360.10 161 314 2.2E-72 T 29-03-2018 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 5.1E-40 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 4.1E-72 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 Gene3D G3DSA:3.40.50.720 1 160 8.6E-80 T 29-03-2018 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 SMART SM00846 2 151 3.6E-98 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 PIRSF PIRSF000149 1 333 1.8E-142 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25360 1d01c2023665765c21ac37ef47c7fee7 334 SUPERFAMILY SSF55347 151 313 4.17E-75 T 29-03-2018 CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 636 3.0E-44 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 Pfam PF00912 Transglycosylase 84 260 1.7E-65 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 SUPERFAMILY SSF56601 295 654 6.84E-105 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 SUPERFAMILY SSF56601 245 264 6.84E-105 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 SUPERFAMILY SSF53955 73 287 3.37E-74 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 640 9.8E-178 T 29-03-2018 CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 Gene3D G3DSA:2.130.10.10 673 817 4.2E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 Gene3D G3DSA:1.10.3810.10 76 274 1.5E-81 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS16310 f612b63f7dbb64f3d58265a1d1a195c9 832 Gene3D G3DSA:3.40.710.10 275 653 3.4E-92 T 29-03-2018 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 Gene3D G3DSA:1.20.1480.30 193 362 0.036 T 29-03-2018 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 278 622 6.0E-10 T 29-03-2018 IPR010090 Phage tail tape measure protein CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 Pfam PF10145 Phage-related minor tail protein 321 516 5.6E-25 T 29-03-2018 IPR010090 Phage tail tape measure protein CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 Gene3D G3DSA:1.20.120.570 10 192 0.018 T 29-03-2018 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 Gene3D G3DSA:1.20.5.1230 527 787 1.4E-22 T 29-03-2018 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 Gene3D G3DSA:1.20.5.1230 865 967 8.9E-12 T 29-03-2018 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 SUPERFAMILY SSF57997 67 254 3.47E-5 T 29-03-2018 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 SUPERFAMILY SSF48371 653 958 4.03E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 SUPERFAMILY SSF48371 574 600 4.03E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS05210 155c45fea27afa9ec2b71125d47543cd 1095 Gene3D G3DSA:1.10.287.700 803 864 2.6E-5 T 29-03-2018 CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 Gene3D G3DSA:3.40.50.720 7 222 3.3E-48 T 29-03-2018 CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 SUPERFAMILY SSF51735 7 206 4.68E-50 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.7E-9 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 Pfam PF00106 short chain dehydrogenase 8 195 2.0E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.8E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.8E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.8E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.8E-19 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16330 609caca49638d8ec239b2ea68378184f 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS28515 b60f9cd3f76dd327c9f7e21b4404fa2f 278 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 272 2.8E-23 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS28515 b60f9cd3f76dd327c9f7e21b4404fa2f 278 PIRSF PIRSF006483 1 278 4.5E-89 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS28515 b60f9cd3f76dd327c9f7e21b4404fa2f 278 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 213 2.0E-65 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 SUPERFAMILY SSF102114 114 355 3.27E-32 T 29-03-2018 CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 Pfam PF12544 Lysine-2,3-aminomutase 321 447 6.6E-62 T 29-03-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 Gene3D G3DSA:3.20.20.70 115 325 7.8E-20 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 TIGRFAM TIGR00238 TIGR00238: KamA family protein 14 342 5.0E-147 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 21 427 3.4E-193 T 29-03-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 Pfam PF13353 4Fe-4S single cluster domain 127 199 4.4E-5 T 29-03-2018 CSW12_RS16475 4a44d56088992b6dcfecb2d2908cdc6e 473 PIRSF PIRSF004911 3 401 1.3E-159 T 29-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CSW12_RS10035 5bcff19716cefc601167fad047e5b14e 185 Gene3D G3DSA:2.160.10.10 13 177 1.4E-40 T 29-03-2018 CSW12_RS10035 5bcff19716cefc601167fad047e5b14e 185 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 86 120 1.2E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS10035 5bcff19716cefc601167fad047e5b14e 185 SUPERFAMILY SSF51161 28 175 3.88E-44 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS10035 5bcff19716cefc601167fad047e5b14e 185 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 94 122 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 SUPERFAMILY SSF52540 154 402 8.52E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 618 38.658 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 29-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 602 3.3E-246 T 29-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 SMART SM00382 194 333 3.6E-26 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 330 3.5E-46 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 Pfam PF06480 FtsH Extracellular 9 104 2.5E-12 T 29-03-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 Gene3D G3DSA:1.10.8.60 349 419 7.4E-24 T 29-03-2018 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 Pfam PF01434 Peptidase family M41 392 601 8.0E-87 T 29-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 SUPERFAMILY SSF140990 412 604 7.32E-72 T 29-03-2018 CSW12_RS27680 7564841f6b16752efd38a4e9b5dee0ca 633 Gene3D G3DSA:3.40.50.300 136 348 4.8E-66 T 29-03-2018 CSW12_RS09265 3084208bb6875ec8fc2a34b00457eab5 423 SUPERFAMILY SSF53383 60 398 1.01E-48 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS09265 3084208bb6875ec8fc2a34b00457eab5 423 Gene3D G3DSA:3.40.640.10 58 271 4.2E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS09265 3084208bb6875ec8fc2a34b00457eab5 423 Pfam PF06838 Methionine gamma-lyase 14 414 4.1E-210 T 29-03-2018 IPR009651 Putative methionine gamma-lyase CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 Gene3D G3DSA:1.10.443.10 111 293 9.7E-49 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 9 299 2.9E-101 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 90 1.1E-23 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 SUPERFAMILY SSF56349 3 293 2.94E-59 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 Gene3D G3DSA:1.10.150.130 3 108 1.2E-26 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 299 57.169 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 Pfam PF00589 Phage integrase family 111 285 2.4E-51 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS08620 89eef454d9326d4a150cb992a6b70664 299 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 9 299 4.8E-110 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CSW12_RS19110 ec32d8fa7953e4ef3ff149ce5c75d04e 482 Gene3D G3DSA:3.40.710.10 31 369 3.7E-68 T 29-03-2018 CSW12_RS19110 ec32d8fa7953e4ef3ff149ce5c75d04e 482 Pfam PF00144 Beta-lactamase 43 354 9.2E-58 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS19110 ec32d8fa7953e4ef3ff149ce5c75d04e 482 SUPERFAMILY SSF56601 31 365 3.83E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS27230 9daf13c9dcbc67e45b3a85cba61b561b 173 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.567 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS27230 9daf13c9dcbc67e45b3a85cba61b561b 173 Gene3D G3DSA:2.40.50.140 1 122 1.2E-42 T 29-03-2018 CSW12_RS27230 9daf13c9dcbc67e45b3a85cba61b561b 173 SUPERFAMILY SSF50249 2 173 5.48E-58 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS27230 9daf13c9dcbc67e45b3a85cba61b561b 173 Pfam PF00436 Single-strand binding protein family 2 103 7.2E-39 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CSW12_RS27230 9daf13c9dcbc67e45b3a85cba61b561b 173 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 173 9.4E-49 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS19820 ed1fb5ff837c5a44a24f850f065d74a3 114 SUPERFAMILY SSF140415 1 114 2.09E-39 T 29-03-2018 IPR023351 YppE-like domain CSW12_RS19820 ed1fb5ff837c5a44a24f850f065d74a3 114 Gene3D G3DSA:1.20.120.440 4 114 3.4E-34 T 29-03-2018 IPR023351 YppE-like domain CSW12_RS19820 ed1fb5ff837c5a44a24f850f065d74a3 114 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 11 112 2.7E-34 T 29-03-2018 IPR014913 Protein of unknown function DUF1798 CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 511 604 3.8E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 SMART SM00387 508 606 0.0025 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 Gene3D G3DSA:3.30.450.40 267 403 3.6E-7 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 Gene3D G3DSA:3.30.565.10 404 604 8.2E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 Pfam PF07730 Histidine kinase 403 467 2.9E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 SUPERFAMILY SSF55781 262 393 2.84E-9 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS15260 d0a3c96e23c04a50c0a00c88c3c92b24 610 SUPERFAMILY SSF55874 467 603 2.1E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 TIGRFAM TIGR00277 HDIG: HDIG domain 333 410 3.1E-26 T 29-03-2018 IPR006675 HDIG domain CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 Pfam PF01966 HD domain 338 429 4.1E-19 T 29-03-2018 IPR006674 HD domain CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 Pfam PF00013 KH domain 214 268 3.5E-6 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 SMART SM00322 209 276 1.1E-6 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 SMART SM00471 333 439 4.7E-14 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 Hamap MF_00335 Ribonuclease Y [rny]. 6 521 25.926 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 SUPERFAMILY SSF109604 317 468 1.59E-30 T 29-03-2018 CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 Gene3D G3DSA:3.30.300.20 154 245 4.2E-11 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 9 521 5.6E-247 T 29-03-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 Pfam PF12072 Domain of unknown function (DUF3552) 7 206 4.0E-77 T 29-03-2018 IPR022711 Ribonuclease Y, N-terminal CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 Gene3D G3DSA:1.10.3210.10 246 457 4.9E-37 T 29-03-2018 CSW12_RS08890 7d3c6501fab5089433d7f6cbcb7df1c4 521 SUPERFAMILY SSF54791 209 305 3.42E-16 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 Pfam PF01791 DeoC/LacD family aldolase 4 205 9.3E-23 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 SUPERFAMILY SSF51569 1 214 1.88E-83 T 29-03-2018 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 211 1.9E-93 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.457 T 29-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 PIRSF PIRSF001357 1 223 2.0E-80 T 29-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 Gene3D G3DSA:3.20.20.70 1 219 1.1E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS18370 70d5390cf15b4fc9276c1c4cdfe294cb 223 SMART SM01133 2 214 1.2E-105 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS19230 31c8a297b0fd83881c3ba8fccfa9b5a5 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 72 91 5.5E-14 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CSW12_RS19230 31c8a297b0fd83881c3ba8fccfa9b5a5 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 194 213 5.5E-14 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CSW12_RS19230 31c8a297b0fd83881c3ba8fccfa9b5a5 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 172 194 5.5E-14 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CSW12_RS19230 31c8a297b0fd83881c3ba8fccfa9b5a5 253 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 15 36 5.5E-14 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CSW12_RS19230 31c8a297b0fd83881c3ba8fccfa9b5a5 253 Pfam PF01311 Bacterial export proteins, family 1 8 237 1.7E-48 T 29-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CSW12_RS15885 b856b0d6a78c35e7b1a4b54720796521 229 Pfam PF03475 3-alpha domain 173 214 3.0E-14 T 29-03-2018 IPR005163 3-alpha domain CSW12_RS15885 b856b0d6a78c35e7b1a4b54720796521 229 SUPERFAMILY SSF50800 4 217 3.4E-71 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CSW12_RS15885 b856b0d6a78c35e7b1a4b54720796521 229 Gene3D G3DSA:2.40.33.20 1 229 3.2E-48 T 29-03-2018 CSW12_RS15885 b856b0d6a78c35e7b1a4b54720796521 229 Pfam PF03473 MOSC domain 53 159 1.1E-23 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 Gene3D G3DSA:3.40.50.1820 36 283 8.5E-45 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 128 141 2.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 98 2.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 PRINTS PR00111 Alpha/beta hydrolase fold signature 142 155 2.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 Pfam PF00561 alpha/beta hydrolase fold 58 157 1.2E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 Pfam PF00561 alpha/beta hydrolase fold 199 266 6.3E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS04430 6715fa53b1f750f87c1f3d264e8b720f 283 SUPERFAMILY SSF53474 31 279 3.65E-56 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 515 1.8E-270 T 29-03-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 453 470 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 366 8.9E-88 T 29-03-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 603 615 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 415 499 1.4E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 Gene3D G3DSA:2.70.70.10 527 687 3.4E-62 T 29-03-2018 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 540 663 3.6E-53 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 541 661 3.8E-48 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 Gene3D G3DSA:3.30.1360.60 439 513 8.7E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 SUPERFAMILY SSF55604 442 513 6.41E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 SUPERFAMILY SSF51261 533 683 4.19E-57 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 Pfam PF02378 Phosphotransferase system, EIIC 13 355 5.8E-100 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS07435 0b2fe95ad682ae4412284b491f620f68 687 Pfam PF00367 phosphotransferase system, EIIB 442 475 3.4E-12 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 SUPERFAMILY SSF50685 408 450 5.23E-8 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 Gene3D G3DSA:2.30.30.410 125 198 8.9E-16 T 29-03-2018 CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 Pfam PF06725 3D domain 411 470 6.7E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 Gene3D G3DSA:2.40.50.110 59 124 2.9E-16 T 29-03-2018 CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 Gene3D G3DSA:2.40.40.10 275 469 2.6E-39 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 Pfam PF08239 Bacterial SH3 domain 133 183 5.6E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 Pfam PF08239 Bacterial SH3 domain 73 123 2.2E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 SMART SM00287 124 187 3.2E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS03320 b47b76894bcbe470ab0deb85fae84f0b 470 SMART SM00287 64 121 3.3E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF50800 70 165 7.33E-27 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:2.40.33.10 83 155 1.6E-27 T 29-03-2018 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF51621 1 75 5.93E-104 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF51621 165 340 5.93E-104 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.50.30.10 474 585 7.0E-30 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.40.1380.20 320 473 2.6E-55 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF52009 465 583 4.19E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 470 4.6E-36 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.20.20.60 1 82 3.1E-21 T 29-03-2018 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 SUPERFAMILY SSF52935 321 473 1.83E-42 T 29-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Pfam PF00224 Pyruvate kinase, barrel domain 1 342 2.7E-156 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Pfam PF00391 PEP-utilising enzyme, mobile domain 504 575 2.0E-21 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 Gene3D G3DSA:3.20.20.60 156 319 2.6E-65 T 29-03-2018 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 ProSitePatterns PS00110 Pyruvate kinase active site signature. 213 225 - T 29-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 1.4E-190 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 267 291 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 215 241 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 242 266 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 59 75 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 311 327 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 184 198 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS22620 4141e922cb2611afd160998c61693f56 585 PRINTS PR01050 Pyruvate kinase family signature 292 310 8.3E-80 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 SUPERFAMILY SSF55729 1 167 5.48E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 Pfam PF00583 Acetyltransferase (GNAT) family 53 156 3.4E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 Gene3D G3DSA:3.40.630.30 1 185 2.8E-31 T 29-03-2018 CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 PRINTS PR01754 Streptothricin acetyltransferase signature 127 142 1.4E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 PRINTS PR01754 Streptothricin acetyltransferase signature 103 118 1.4E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 PRINTS PR01754 Streptothricin acetyltransferase signature 171 184 1.4E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CSW12_RS11995 b72fb5b4d6cbc5e898c0a852bff8c5d3 185 PRINTS PR01754 Streptothricin acetyltransferase signature 148 164 1.4E-19 T 29-03-2018 IPR008125 Streptothricin acetyltransferase CSW12_RS25845 4207e9625561555114d3a45b0d550492 341 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 331 8.4E-37 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.015 T 29-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 Gene3D G3DSA:3.30.1440.10 1 179 1.2E-81 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 SUPERFAMILY SSF55282 3 178 6.12E-78 T 29-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 29-03-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 PIRSF PIRSF002161 1 179 1.9E-69 T 29-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.0E-42 T 29-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28045 b00cbd747107e84b39e53669dd31a287 179 Pfam PF00281 Ribosomal protein L5 24 80 2.0E-28 T 29-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27155 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 SUPERFAMILY SSF56281 3 251 1.27E-45 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS27155 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 6.1E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS27155 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 Gene3D G3DSA:3.60.15.10 9 260 6.5E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS27155 2ef2d411ce7b8a0316fb8bcf0be14c7b 264 SMART SM00849 13 193 5.4E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS11320 b7072a2811e54ccb441c92a20d267af5 199 Gene3D G3DSA:2.60.20.10 18 155 0.0056 T 29-03-2018 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 Pfam PF00108 Thiolase, N-terminal domain 5 259 1.6E-69 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 Pfam PF02803 Thiolase, C-terminal domain 268 388 1.1E-49 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 SUPERFAMILY SSF53901 268 389 3.73E-44 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 ProSitePatterns PS00099 Thiolases active site. 371 384 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 6.0E-135 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 Gene3D G3DSA:3.40.47.10 143 263 1.0E-20 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 Gene3D G3DSA:3.40.47.10 1 134 5.4E-28 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 Gene3D G3DSA:3.40.47.10 264 387 2.1E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 SUPERFAMILY SSF53901 1 262 4.01E-68 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS24825 10148a6df00888a3df150802f5d22075 390 PIRSF PIRSF000429 1 390 1.8E-125 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS04140 ffc3d25c6dfa5164626723f4092f09f6 606 Gene3D G3DSA:3.30.70.270 109 366 1.0E-38 T 29-03-2018 CSW12_RS04140 ffc3d25c6dfa5164626723f4092f09f6 606 Pfam PF01348 Type II intron maturase 410 488 7.4E-11 T 29-03-2018 IPR024937 Domain X GO:0006397 CSW12_RS04140 ffc3d25c6dfa5164626723f4092f09f6 606 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 88 234 4.7E-34 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS04140 ffc3d25c6dfa5164626723f4092f09f6 606 SUPERFAMILY SSF56672 42 232 6.0E-46 T 29-03-2018 CSW12_RS04140 ffc3d25c6dfa5164626723f4092f09f6 606 SUPERFAMILY SSF56672 303 369 6.0E-46 T 29-03-2018 CSW12_RS04140 ffc3d25c6dfa5164626723f4092f09f6 606 Gene3D G3DSA:3.40.1800.10 530 605 4.6E-5 T 29-03-2018 CSW12_RS09570 8ccdadc0796bc9192f45ed918ff41f7c 150 SMART SM00701 1 129 3.2E-8 T 29-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS09570 8ccdadc0796bc9192f45ed918ff41f7c 150 Gene3D G3DSA:3.40.80.10 11 150 9.8E-40 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS09570 8ccdadc0796bc9192f45ed918ff41f7c 150 SMART SM00644 9 137 7.1E-17 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS09570 8ccdadc0796bc9192f45ed918ff41f7c 150 SUPERFAMILY SSF55846 14 140 1.31E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS09570 8ccdadc0796bc9192f45ed918ff41f7c 150 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 18 137 3.9E-28 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS15190 0455d5b45ba759f5fbb2e9da445f44a3 357 Gene3D G3DSA:3.40.1090.10 2 349 2.0E-47 T 29-03-2018 CSW12_RS15190 0455d5b45ba759f5fbb2e9da445f44a3 357 SUPERFAMILY SSF52151 4 196 2.88E-41 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS15190 0455d5b45ba759f5fbb2e9da445f44a3 357 Pfam PF01734 Patatin-like phospholipase 8 194 1.1E-33 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 Pfam PF00107 Zinc-binding dehydrogenase 166 259 1.1E-13 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 SUPERFAMILY SSF51735 127 276 1.13E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 Gene3D G3DSA:3.40.50.720 157 255 4.7E-19 T 29-03-2018 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 Gene3D G3DSA:3.40.50.720 256 285 0.38 T 29-03-2018 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 SMART SM00829 10 299 1.6E-10 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 99 7.8E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 Gene3D G3DSA:3.90.180.10 1 156 1.4E-41 T 29-03-2018 CSW12_RS28335 a0e96b7ba7a66602dc451a0630056bef 302 SUPERFAMILY SSF50129 1 161 1.83E-30 T 29-03-2018 IPR011032 GroES-like CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 Pfam PF08453 Peptidase family M9 N-terminal 122 303 5.2E-48 T 29-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 Gene3D G3DSA:2.60.120.380 786 902 1.0E-16 T 29-03-2018 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 188 206 7.6E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 491 507 7.6E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 554 569 7.6E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 474 488 7.6E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 528 546 7.6E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 SUPERFAMILY SSF89260 793 898 1.57E-18 T 29-03-2018 CSW12_RS29945 4c1ed47afbb8691015f01792c1420d6c 905 Pfam PF01752 Collagenase 328 661 3.7E-72 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 Pfam PF07690 Major Facilitator Superfamily 27 417 3.1E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 1.1E-5 T 29-03-2018 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 311 335 1.1E-5 T 29-03-2018 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 1.1E-5 T 29-03-2018 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 Gene3D G3DSA:1.20.1250.20 268 491 4.7E-26 T 29-03-2018 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 24 440 3.7E-100 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 Gene3D G3DSA:1.20.1250.20 14 202 2.9E-28 T 29-03-2018 CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 SUPERFAMILY SSF103473 16 206 1.44E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS03995 eff9a9166b1049e4b8bf048bf73f6ab0 491 SUPERFAMILY SSF103473 257 480 1.44E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS22820 6d951ed18eb3375425dd802eb68e47cc 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 122 136 1.3E-6 T 29-03-2018 CSW12_RS22820 6d951ed18eb3375425dd802eb68e47cc 330 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 219 243 1.3E-6 T 29-03-2018 CSW12_RS22820 6d951ed18eb3375425dd802eb68e47cc 330 SUPERFAMILY SSF53335 10 310 1.37E-43 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS22820 6d951ed18eb3375425dd802eb68e47cc 330 Pfam PF02384 N-6 DNA Methylase 98 319 9.7E-15 T 29-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CSW12_RS22820 6d951ed18eb3375425dd802eb68e47cc 330 PIRSF PIRSF026567 2 330 1.2E-145 T 29-03-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted CSW12_RS22820 6d951ed18eb3375425dd802eb68e47cc 330 Gene3D G3DSA:3.40.50.150 88 330 1.0E-33 T 29-03-2018 CSW12_RS12045 1dd2f3f0c83c0efe36e95eb47b3eefe9 341 SUPERFAMILY SSF53474 67 340 4.18E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12045 1dd2f3f0c83c0efe36e95eb47b3eefe9 341 Pfam PF07859 alpha/beta hydrolase fold 99 306 3.6E-24 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CSW12_RS12045 1dd2f3f0c83c0efe36e95eb47b3eefe9 341 Gene3D G3DSA:3.40.50.1820 60 340 1.0E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 Pfam PF04542 Sigma-70 region 2 20 83 1.0E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 Gene3D G3DSA:1.10.10.10 100 175 4.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 41 72 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 169 2.7E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 Pfam PF08281 Sigma-70, region 4 117 166 5.1E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 Gene3D G3DSA:1.10.1740.10 8 88 1.8E-17 T 29-03-2018 CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 SUPERFAMILY SSF88946 12 91 9.02E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15105 c9188b6a151101927a71c1cbcfc082f0 179 SUPERFAMILY SSF88659 104 171 6.54E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 Pfam PF02954 Bacterial regulatory protein, Fis family 423 463 3.1E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 SUPERFAMILY SSF52540 148 385 1.42E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 Gene3D G3DSA:1.10.8.60 321 380 5.5E-20 T 29-03-2018 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 466 8.1E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 8.1E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 Gene3D G3DSA:1.10.10.60 381 466 6.4E-20 T 29-03-2018 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 Gene3D G3DSA:3.40.50.300 142 319 1.2E-27 T 29-03-2018 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 Pfam PF00158 Sigma-54 interaction domain 149 314 1.3E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 SUPERFAMILY SSF46689 361 465 1.3E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 Gene3D G3DSA:3.30.450.20 2 135 6.7E-6 T 29-03-2018 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 SUPERFAMILY SSF55785 9 121 1.39E-6 T 29-03-2018 IPR000014 PAS domain CSW12_RS01050 c16a7ac2d178d09f3d525bc4529846fb 467 SMART SM00382 169 311 4.3E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 Pfam PF02910 Fumarate reductase flavoprotein C-term 412 493 3.8E-12 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 SUPERFAMILY SSF46977 410 493 7.46E-22 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 Gene3D G3DSA:3.50.50.60 2 196 1.4E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 SUPERFAMILY SSF51905 333 391 1.1E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 SUPERFAMILY SSF51905 3 245 1.1E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 489 5.6E-162 T 29-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 Gene3D G3DSA:3.90.700.10 226 312 3.3E-28 T 29-03-2018 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 Pfam PF00890 FAD binding domain 5 369 1.8E-86 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 Gene3D G3DSA:1.20.58.100 386 492 8.3E-19 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 SUPERFAMILY SSF56425 219 329 1.79E-33 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 Gene3D G3DSA:3.50.50.60 313 385 1.4E-15 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 332 354 3.0E-5 T 29-03-2018 CSW12_RS21785 2fdcf98ac1e7b2da6ef52b3a495be16d 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.0E-5 T 29-03-2018 CSW12_RS26345 7103a7b665e3264b2675d99344f0aa4b 84 Gene3D G3DSA:1.20.1250.20 11 81 9.8E-4 T 29-03-2018 CSW12_RS26345 7103a7b665e3264b2675d99344f0aa4b 84 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 22 74 1.0E-14 T 29-03-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 SMART SM00062 37 255 1.7E-69 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 SUPERFAMILY SSF53850 1 255 4.56E-70 T 29-03-2018 CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 SMART SM00079 37 254 7.3E-4 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 Gene3D G3DSA:3.40.190.10 27 177 1.5E-44 T 29-03-2018 CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 Gene3D G3DSA:3.40.190.10 178 252 7.7E-15 T 29-03-2018 CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 253 3.1E-68 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS00680 0adf5ec987795375523e95b417d77dbf 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 Gene3D G3DSA:3.30.70.940 2 116 1.6E-43 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 SUPERFAMILY SSF82679 2 114 3.53E-40 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 Gene3D G3DSA:2.30.30.30 118 177 7.7E-19 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 SUPERFAMILY SSF50104 121 177 1.35E-18 T 29-03-2018 IPR008991 Translation protein SH3-like domain CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 Pfam PF00467 KOW motif 129 158 4.0E-5 T 29-03-2018 IPR005824 KOW CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.208 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 SMART SM00738 2 113 4.4E-51 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 Pfam PF02357 Transcription termination factor nusG 3 109 1.0E-28 T 29-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 3.1E-65 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.1E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.1E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.1E-20 T 29-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CSW12_RS27910 e624392e043dda55457abed19b2a25d8 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 29-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 1213 1377 4.08E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 563 715 1.26E-21 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 123 246 3.13E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 1254 1292 1.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 733 766 0.23 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 1279 1312 0.077 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 1011 1044 290.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 767 803 310.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 1245 1278 270.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 189 222 350.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 912 944 0.13 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 563 596 49.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 664 697 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 1313 1346 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 597 630 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 878 911 21.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SMART SM00028 123 156 100.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Pfam PF09295 ChAPs (Chs5p-Arf1p-binding proteins) 1192 1312 1.3E-4 T 29-03-2018 IPR015374 Chs5p-Arf1p binding CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 709 792 1.4E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 928 978 1.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:3.90.70.10 315 463 1.3E-18 T 29-03-2018 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Pfam PF13529 Peptidase_C39 like family 312 418 6.5E-16 T 29-03-2018 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 648 708 2.0E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 1325 1397 1.5E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 485 647 4.7E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 1293 1324 2.3E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 75 173 2.0E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.120 1001 1147 8.0E-8 T 29-03-2018 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Pfam PF13432 Tetratricopeptide repeat 635 686 0.0011 T 29-03-2018 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Pfam PF13432 Tetratricopeptide repeat 738 786 0.013 T 29-03-2018 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Pfam PF13181 Tetratricopeptide repeat 914 943 9.4E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 732 817 1.25E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 846 980 1.25E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 873 927 5.1E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 1016 1097 1.73E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 SUPERFAMILY SSF48452 1158 1208 1.73E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 1148 1253 1.9E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS17075 16525291642f04b5c9c51d2523fa5a8f 1400 Gene3D G3DSA:1.25.40.10 174 292 9.7E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS22090 737d6381917d038c02c3c36ddca7afe1 218 Pfam PF01965 DJ-1/PfpI family 26 211 1.6E-13 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS22090 737d6381917d038c02c3c36ddca7afe1 218 Gene3D G3DSA:3.40.50.880 1 218 1.2E-47 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS22090 737d6381917d038c02c3c36ddca7afe1 218 SUPERFAMILY SSF52317 1 214 2.14E-60 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS19030 5d5a6472ce8f35ab7a44b517e07a86b0 299 Gene3D G3DSA:1.20.1510.10 11 209 1.8E-58 T 29-03-2018 CSW12_RS19030 5d5a6472ce8f35ab7a44b517e07a86b0 299 SUPERFAMILY SSF160240 213 285 8.63E-10 T 29-03-2018 CSW12_RS19030 5d5a6472ce8f35ab7a44b517e07a86b0 299 SUPERFAMILY SSF161111 9 210 2.35E-58 T 29-03-2018 CSW12_RS19030 5d5a6472ce8f35ab7a44b517e07a86b0 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 287 1.9E-91 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CSW12_RS19030 5d5a6472ce8f35ab7a44b517e07a86b0 299 Gene3D G3DSA:3.30.70.1350 210 287 7.7E-13 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CSW12_RS19030 5d5a6472ce8f35ab7a44b517e07a86b0 299 Pfam PF01545 Cation efflux family 16 209 1.6E-51 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CSW12_RS05030 6d758c2bdd25efe9ec19e5a4a5ccda6b 121 Pfam PF07457 Protein of unknown function (DUF1516) 2 111 2.5E-32 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CSW12_RS05030 6d758c2bdd25efe9ec19e5a4a5ccda6b 121 Hamap MF_01536 UPF0344 protein . 1 121 16.783 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CSW12_RS05030 6d758c2bdd25efe9ec19e5a4a5ccda6b 121 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 121 2.0E-61 T 29-03-2018 IPR010899 Protein of unknown function UPF0344 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 151 1.7E-10 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 Gene3D G3DSA:3.30.390.50 247 329 8.8E-27 T 29-03-2018 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 327 7.5E-30 T 29-03-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 SUPERFAMILY SSF55681 2 241 1.49E-81 T 29-03-2018 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 SUPERFAMILY SSF82649 243 329 5.75E-27 T 29-03-2018 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 1.9E-130 T 29-03-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 CSW12_RS04760 b3e692a5bdeeb400462883cbbdb97041 329 Gene3D G3DSA:3.30.930.10 2 246 1.3E-69 T 29-03-2018 CSW12_RS26225 5351869d18ccbb397acfc5afde8a93b3 506 Pfam PF00361 Proton-conducting membrane transporter 129 427 1.3E-68 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26225 5351869d18ccbb397acfc5afde8a93b3 506 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 9 485 17.164 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CSW12_RS26225 5351869d18ccbb397acfc5afde8a93b3 506 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 12 483 1.8E-114 T 29-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CSW12_RS08055 194a3920c5ae9aa397d329ddc12f2829 332 Hamap MF_01243 Formamidase [amiF]. 1 332 69.745 T 29-03-2018 IPR022843 Formamidase GO:0004328|GO:0006807 KEGG: 00460+3.5.1.49|KEGG: 00630+3.5.1.49|KEGG: 00910+3.5.1.49|MetaCyc: PWY-7142 CSW12_RS08055 194a3920c5ae9aa397d329ddc12f2829 332 Pfam PF00795 Carbon-nitrogen hydrolase 16 266 4.7E-36 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CSW12_RS08055 194a3920c5ae9aa397d329ddc12f2829 332 SUPERFAMILY SSF56317 16 274 8.37E-59 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CSW12_RS08055 194a3920c5ae9aa397d329ddc12f2829 332 Gene3D G3DSA:3.60.110.10 9 305 3.9E-57 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 SUPERFAMILY SSF109604 500 678 5.34E-13 T 29-03-2018 CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 Gene3D G3DSA:1.10.3210.10 448 682 1.1E-32 T 29-03-2018 CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 TIGRFAM TIGR00277 HDIG: HDIG domain 498 596 2.4E-26 T 29-03-2018 IPR006675 HDIG domain CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 Pfam PF07698 7TM receptor with intracellular HD hydrolase 277 476 6.7E-44 T 29-03-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 Pfam PF07697 7TM-HD extracellular 51 270 2.4E-33 T 29-03-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 Pfam PF01966 HD domain 501 643 5.4E-17 T 29-03-2018 IPR006674 HD domain CSW12_RS21130 f1b4b736fc4fa590208292738251d5bc 714 SMART SM00471 497 653 4.2E-10 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 SMART SM00421 531 588 4.5E-19 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 Pfam PF00072 Response regulator receiver domain 386 496 3.9E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 Gene3D G3DSA:3.30.565.10 246 381 1.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 Gene3D G3DSA:1.10.10.10 508 595 2.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 SUPERFAMILY SSF55874 252 373 9.56E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 SUPERFAMILY SSF52172 383 546 1.71E-32 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 Pfam PF07730 Histidine kinase 184 245 5.1E-13 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 SUPERFAMILY SSF46894 527 594 5.78E-18 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 Gene3D G3DSA:3.40.50.2300 382 507 1.7E-33 T 29-03-2018 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 548 564 1.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 534 548 1.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 564 576 1.9E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 PIRSF PIRSF037435 1 595 0.0 T 29-03-2018 IPR017206 Signal transduction histidine kinase, hybrid-type, BC3207, predicted CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 SMART SM00448 383 496 8.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 SMART SM00387 286 376 0.0096 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11840 cc04a1b768465b4b482b9113e31698c6 595 Pfam PF00196 Bacterial regulatory proteins, luxR family 534 588 2.2E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 ProDom PD003946 PHOSPHOLIPASE C PLCB HYDROLASE PRECURSOR PHOSPHATIDYLCHOLINE SIGNAL CHOLINEPHOSPHOHYDROLASE TOXIN PLC 47 275 3.0E-134 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 107 120 7.1E-28 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 130 152 7.1E-28 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 153 177 7.1E-28 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 180 197 7.1E-28 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 PRINTS PR00479 Prokaryotic zinc-dependent phospholipase C signature 266 276 7.1E-28 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 SUPERFAMILY SSF48537 39 281 4.84E-63 T 29-03-2018 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 SMART SM00770 1 283 1.7E-131 T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 Pfam PF00882 Zinc dependent phospholipase C 51 230 8.5E-21 T 29-03-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 Gene3D G3DSA:1.10.575.10 39 283 1.6E-34 T 29-03-2018 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 CSW12_RS02345 702b145799bbdcbdd8760d0e2554ebe3 283 ProSitePatterns PS00384 Prokaryotic zinc-dependent phospholipase C signature. 156 169 - T 29-03-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CSW12_RS05295 7a703d091a34ed2df494408252a8b298 298 SUPERFAMILY SSF47413 5 65 1.83E-15 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS05295 7a703d091a34ed2df494408252a8b298 298 Gene3D G3DSA:1.25.40.10 97 298 1.0E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS05295 7a703d091a34ed2df494408252a8b298 298 SMART SM00530 9 63 5.2E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05295 7a703d091a34ed2df494408252a8b298 298 Gene3D G3DSA:1.10.260.40 2 96 4.6E-17 T 29-03-2018 CSW12_RS05295 7a703d091a34ed2df494408252a8b298 298 Pfam PF12844 Helix-turn-helix domain 9 67 2.3E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05295 7a703d091a34ed2df494408252a8b298 298 SUPERFAMILY SSF48452 114 273 6.64E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS05990 9627ad154fd8ac7b437c3d40891e8a46 205 SUPERFAMILY SSF48317 5 194 1.18E-33 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS05990 9627ad154fd8ac7b437c3d40891e8a46 205 SMART SM00014 77 189 1.1E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS05990 9627ad154fd8ac7b437c3d40891e8a46 205 Gene3D G3DSA:1.20.144.10 24 204 1.6E-26 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS05990 9627ad154fd8ac7b437c3d40891e8a46 205 Pfam PF01569 PAP2 superfamily 82 192 7.5E-18 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS05980 4658f93d8e229c4394883ab6e1d3c727 266 SUPERFAMILY SSF161098 4 253 1.14E-60 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05980 4658f93d8e229c4394883ab6e1d3c727 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 249 3.0E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05980 4658f93d8e229c4394883ab6e1d3c727 266 Gene3D G3DSA:1.10.3720.10 3 258 5.6E-50 T 29-03-2018 CSW12_RS01850 70ebe2c5eb2ef0bb146279a71296cc68 465 Pfam PF13520 Amino acid permease 7 427 9.4E-51 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS01850 70ebe2c5eb2ef0bb146279a71296cc68 465 PIRSF PIRSF006060 1 463 9.9E-56 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 Gene3D G3DSA:1.10.10.10 1 64 1.7E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 Gene3D G3DSA:3.40.50.1360 81 238 1.5E-23 T 29-03-2018 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.1E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 4.9E-14 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 SUPERFAMILY SSF46785 4 59 8.21E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 Pfam PF00455 DeoR C terminal sensor domain 82 231 2.8E-30 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 SUPERFAMILY SSF100950 82 231 1.34E-19 T 29-03-2018 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 SMART SM01134 74 232 2.2E-37 T 29-03-2018 CSW12_RS13840 c11948eaf8e326586b168b8f9f8f11d5 254 SMART SM00420 6 58 1.4E-10 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.4E-36 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.164 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 SMART SM01403 7 101 8.1E-60 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 Gene3D G3DSA:3.30.70.600 4 102 3.0E-37 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 SUPERFAMILY SSF54999 5 102 1.2E-38 T 29-03-2018 IPR027486 Ribosomal protein S10 domain CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 29-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27980 35868332db1e892ba7188e536bd58957 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.5E-46 T 29-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS00570 6c090eaa63d7a5b528dbea672b1d8dba 213 SUPERFAMILY SSF53639 2 212 6.08E-62 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS00570 6c090eaa63d7a5b528dbea672b1d8dba 213 Gene3D G3DSA:3.40.225.10 3 213 1.2E-59 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS00570 6c090eaa63d7a5b528dbea672b1d8dba 213 SMART SM01007 8 184 7.4E-59 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS00570 6c090eaa63d7a5b528dbea672b1d8dba 213 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 184 1.9E-43 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS03805 36f660ea37e77d1a97868e703f99acb6 317 SUPERFAMILY SSF53335 77 297 6.03E-17 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS03805 36f660ea37e77d1a97868e703f99acb6 317 Pfam PF01170 Putative RNA methylase family UPF0020 158 263 1.0E-6 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS03805 36f660ea37e77d1a97868e703f99acb6 317 Gene3D G3DSA:3.40.50.150 153 317 9.6E-21 T 29-03-2018 CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 Gene3D G3DSA:3.60.20.10 1 222 2.6E-52 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 SUPERFAMILY SSF52402 231 380 2.0E-90 T 29-03-2018 CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 SUPERFAMILY SSF52402 467 605 2.0E-90 T 29-03-2018 CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 PIRSF PIRSF001589 1 630 4.1E-196 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 Pfam PF00733 Asparagine synthase 241 610 8.8E-114 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 Pfam PF13537 Glutamine amidotransferase domain 51 168 4.7E-46 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 SUPERFAMILY SSF56235 1 224 3.26E-62 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 Gene3D G3DSA:3.40.50.620 223 617 2.9E-86 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS16790 81a5488100f66f3692824a003189c1b4 633 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 6.5E-171 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS19530 d53d11113fe24f4946b08c6434c072c2 450 PIRSF PIRSF000521 31 450 1.6E-36 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS19530 d53d11113fe24f4946b08c6434c072c2 450 Pfam PF00202 Aminotransferase class-III 31 446 8.2E-111 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS19530 d53d11113fe24f4946b08c6434c072c2 450 Gene3D G3DSA:3.40.640.10 55 325 1.2E-78 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS19530 d53d11113fe24f4946b08c6434c072c2 450 SUPERFAMILY SSF53383 20 448 1.13E-123 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS19530 d53d11113fe24f4946b08c6434c072c2 450 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS19530 d53d11113fe24f4946b08c6434c072c2 450 Gene3D G3DSA:3.90.1150.10 326 450 3.6E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 Gene3D G3DSA:3.90.76.10 63 180 9.4E-31 T 29-03-2018 CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 472 2.7E-85 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 Gene3D G3DSA:3.40.190.10 181 319 6.9E-31 T 29-03-2018 CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 Gene3D G3DSA:3.10.105.10 320 522 1.0E-54 T 29-03-2018 CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 95 117 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 PIRSF PIRSF002741 22 548 1.0E-114 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS28580 83460e9fab12bb0042edb708b109f012 555 SUPERFAMILY SSF53850 44 540 3.61E-124 T 29-03-2018 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 SUPERFAMILY SSF118215 6 400 8.37E-120 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 Gene3D G3DSA:1.10.3860.10 1 406 5.1E-134 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 353 373 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 189 208 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 PRINTS PR00173 Glutamate-aspartate symporter signature 224 243 2.8E-51 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06515 25497edfc0a7321c733acf75ae1956d9 411 Pfam PF00375 Sodium:dicarboxylate symporter family 6 398 2.5E-132 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 SUPERFAMILY SSF48019 238 419 3.68E-70 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Pfam PF12002 MgsA AAA+ ATPase C terminal 253 418 9.5E-66 T 29-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Gene3D G3DSA:1.10.3710.10 333 428 6.7E-32 T 29-03-2018 CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Pfam PF16193 AAA C-terminal domain 172 252 1.3E-24 T 29-03-2018 IPR032423 AAA C-terminal domain CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Gene3D G3DSA:1.20.272.10 237 330 8.4E-36 T 29-03-2018 CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 6.2E-15 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 SUPERFAMILY SSF52540 3 228 2.85E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 SMART SM00382 38 150 1.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Gene3D G3DSA:3.40.50.300 1 138 7.4E-29 T 29-03-2018 CSW12_RS21630 3d6b89ebf4f69dbb23d5716a9d5e3a20 428 Gene3D G3DSA:1.10.8.60 139 228 3.8E-22 T 29-03-2018 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 176 1.7E-39 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Gene3D G3DSA:2.170.190.11 61 143 1.0E-23 T 29-03-2018 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 SUPERFAMILY SSF53218 186 329 4.19E-40 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 1.8E-17 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Gene3D G3DSA:3.40.980.10 172 334 3.0E-48 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Gene3D G3DSA:3.90.105.10 144 171 2.1E-9 T 29-03-2018 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Gene3D G3DSA:3.90.105.10 26 60 8.1E-8 T 29-03-2018 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Gene3D G3DSA:2.40.340.10 338 413 7.0E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 1.4E-32 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 SUPERFAMILY SSF63882 8 184 2.09E-50 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 Pfam PF00994 Probable molybdopterin binding domain 189 326 1.5E-25 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 SUPERFAMILY SSF63867 338 412 2.62E-16 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23300 a16d8553203d38a380f0e509fc17b73a 429 SMART SM00852 189 327 3.1E-38 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1184 1290 2.8E-8 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 627 760 1.8E-7 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2362 2469 6.5E-9 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1446 1552 4.2E-9 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1704 1810 1.5E-10 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 2099 2202 8.7E-10 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1835 1942 5.2E-9 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1965 2071 1.2E-7 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 1316 1421 4.9E-8 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR04226 RrgB_K2N_iso_D2: fimbrial isopeptide formation D2 domain 795 897 1.8E-9 T 29-03-2018 IPR026466 Fimbrial isopeptide formation D2 domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 61 181 0.013 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 921 1049 2.9E-18 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 2095 2227 5.5E-17 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 789 920 5.4E-17 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1313 1443 8.7E-17 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1963 2094 5.8E-16 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 2228 2358 1.0E-16 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1050 1182 7.0E-18 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1444 1572 6.3E-19 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1183 1311 1.6E-16 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1573 1702 1.5E-16 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 625 786 1.9E-15 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 2491 2647 3.5E-14 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 2359 2490 2.5E-17 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1703 1831 6.4E-20 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Gene3D G3DSA:2.60.40.740 1832 1960 6.2E-18 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2845 2879 1.2E-4 T 29-03-2018 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF00746 LPXTG cell wall anchor motif 2839 2879 9.1E-5 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1185 1236 2.8E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1446 1535 3.5E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1837 1889 1.7E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 2098 2192 1.2E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1316 1376 1.0E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 2495 2551 3.6E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1053 1147 4.5E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1706 1799 1.9E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 Pfam PF01345 Domain of unknown function DUF11 1577 1666 3.0E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 SUPERFAMILY SSF49401 2373 2478 4.97E-5 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1186 1238 1.8E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2099 2151 6.9E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 793 845 2.5E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1707 1759 2.8E-12 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 925 975 4.6E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1838 1890 1.6E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1317 1364 1.7E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1447 1499 2.3E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1578 1630 1.2E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2496 2546 3.0E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2230 2277 1.4E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1968 2020 2.9E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1055 1107 1.9E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS24425 bdc0a0d20ce42fcda5b052a73c2b49b3 2880 SUPERFAMILY SSF49401 1457 1566 7.95E-6 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Gene3D G3DSA:3.90.105.10 25 60 1.1E-8 T 29-03-2018 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Gene3D G3DSA:3.90.105.10 143 170 3.6E-7 T 29-03-2018 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Pfam PF03454 MoeA C-terminal region (domain IV) 339 410 4.6E-16 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Gene3D G3DSA:3.40.980.10 171 332 1.3E-48 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 SUPERFAMILY SSF63867 336 412 5.49E-17 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Pfam PF03453 MoeA N-terminal region (domain I and II) 7 175 1.5E-37 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 SUPERFAMILY SSF53218 186 327 2.36E-38 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 SUPERFAMILY SSF63882 7 184 1.26E-49 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Gene3D G3DSA:2.170.190.11 61 142 5.5E-24 T 29-03-2018 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Pfam PF00994 Probable molybdopterin binding domain 190 325 1.2E-23 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 SMART SM00852 188 326 1.3E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 Gene3D G3DSA:2.40.340.10 336 412 1.9E-16 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09930 b3bdb7aa6a335c9f13ae8743d319a243 435 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 185 322 2.9E-30 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS20225 2b26a16fe8e74f29ba603558c213f76f 317 SUPERFAMILY SSF56281 4 300 1.1E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20225 2b26a16fe8e74f29ba603558c213f76f 317 Pfam PF00753 Metallo-beta-lactamase superfamily 17 231 1.0E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20225 2b26a16fe8e74f29ba603558c213f76f 317 Gene3D G3DSA:3.60.15.10 1 259 1.3E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20225 2b26a16fe8e74f29ba603558c213f76f 317 SMART SM00849 17 231 1.3E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 51.088 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.4E-82 T 29-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 SMART SM00841 129 184 3.2E-34 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 1.9E-26 T 29-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 4.3E-28 T 29-03-2018 IPR013185 Translation elongation factor, KOW-like CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 2.9E-22 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 SUPERFAMILY SSF50104 1 63 4.21E-22 T 29-03-2018 IPR008991 Translation protein SH3-like domain CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 PIRSF PIRSF005901 1 185 1.3E-72 T 29-03-2018 IPR020599 Translation elongation factor P/YeiP CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Gene3D G3DSA:2.30.30.30 2 61 4.1E-27 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 SUPERFAMILY SSF50249 128 185 3.22E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 SUPERFAMILY SSF50249 65 129 6.0E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Gene3D G3DSA:2.40.50.140 129 184 5.9E-27 T 29-03-2018 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 Gene3D G3DSA:2.40.50.140 64 127 1.9E-25 T 29-03-2018 CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 29-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CSW12_RS20575 3643d82e5a404222e791bffd3f14569a 185 SMART SM01185 67 121 1.1E-24 T 29-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 SUPERFAMILY SSF48403 9 158 4.51E-38 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 Pfam PF13606 Ankyrin repeat 105 130 0.0047 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 Gene3D G3DSA:1.25.40.20 3 163 1.0E-42 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 PRINTS PR01415 Ankyrin repeat signature 37 52 3.5E-8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 PRINTS PR01415 Ankyrin repeat signature 87 101 3.5E-8 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 SMART SM00248 104 133 0.021 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 SMART SM00248 71 100 0.0021 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 SMART SM00248 36 65 6.9E-7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 SMART SM00248 2 31 3900.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS13410 d63b33564c71d9ef1a9eafa703968a02 163 Pfam PF12796 Ankyrin repeats (3 copies) 8 101 1.0E-16 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 Gene3D G3DSA:3.40.50.300 94 321 1.4E-51 T 29-03-2018 CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 Gene3D G3DSA:3.30.300.130 1 93 5.1E-10 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 109 346 3.2E-84 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 SUPERFAMILY SSF52540 101 315 5.75E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 SUPERFAMILY SSF117916 1 69 5.23E-7 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 Pfam PF01883 Iron-sulfur cluster assembly protein 4 57 2.3E-5 T 29-03-2018 IPR002744 MIP18 family-like CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 ProSitePatterns PS01215 Mrp family signature. 212 228 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CSW12_RS28170 52861993b2b5e7d42c59d1e0ce989019 355 Hamap MF_02040 Iron-sulfur cluster carrier protein. 99 347 33.87 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CSW12_RS21465 ac95e1c92ca9a6a8b4c7f61123d23455 272 Pfam PF00005 ABC transporter 18 165 2.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS21465 ac95e1c92ca9a6a8b4c7f61123d23455 272 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS21465 ac95e1c92ca9a6a8b4c7f61123d23455 272 SUPERFAMILY SSF52540 2 227 2.72E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21465 ac95e1c92ca9a6a8b4c7f61123d23455 272 Gene3D G3DSA:3.40.50.300 1 233 4.5E-57 T 29-03-2018 CSW12_RS21465 ac95e1c92ca9a6a8b4c7f61123d23455 272 SMART SM00382 26 215 2.2E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 Pfam PF00717 Peptidase S24-like 34 99 1.8E-16 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 ProSitePatterns PS00761 Signal peptidases I signature 3. 135 148 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 Gene3D G3DSA:2.10.109.10 24 177 2.3E-39 T 29-03-2018 CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 SUPERFAMILY SSF51306 27 177 4.97E-45 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 171 8.3E-49 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 76 88 4.5E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 130 149 4.5E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS00970 99ad9e5c5f2110d56b47b20fb959513a 178 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 4.5E-19 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS18980 65906ff82a2aedae35ef70aed189e633 467 Pfam PF03553 Na+/H+ antiporter family 159 451 7.8E-67 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CSW12_RS18980 65906ff82a2aedae35ef70aed189e633 467 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 457 9.3E-200 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CSW12_RS30205 2a0537359661e13bed8fdc3f5971a174 86 Pfam PF02810 SEC-C motif 63 78 5.4E-5 T 29-03-2018 IPR004027 SEC-C motif CSW12_RS30205 2a0537359661e13bed8fdc3f5971a174 86 SUPERFAMILY SSF103642 62 81 4.41E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.740 584 718 2.1E-15 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.740 719 859 6.6E-17 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.740 452 583 1.1E-18 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2126 2183 3.14E-5 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.1280 300 451 5.3E-33 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2212 2278 1.53E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2588 2651 3.49E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1266 1328 1.77E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 449 584 1.44E-27 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1930 1995 5.1E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.10 1156 1247 9.2E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 3059 3121 1.14E-5 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2960 3024 1.37E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2867 2929 5.49E-8 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 1008 1141 4.97E-26 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1840 1901 3.81E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 724 853 2.48E-18 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1554 1618 1.88E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1360 1423 6.67E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Pfam PF05737 Collagen binding domain 587 723 1.1E-10 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Pfam PF05737 Collagen binding domain 867 989 2.6E-19 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Pfam PF05737 Collagen binding domain 732 849 9.1E-5 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Pfam PF05737 Collagen binding domain 448 574 1.6E-20 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Pfam PF05737 Collagen binding domain 1014 1135 4.2E-13 T 29-03-2018 IPR008456 Collagen binding domain GO:0005518 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1644 1706 4.32E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.1280 24 177 1.1E-21 T 29-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CSW12_RS26580 945032594a329342e569957dd0014944 3226 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 3192 3225 2.3E-4 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 305 444 2.24E-29 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2399 2460 4.71E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2685 2745 2.55E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1170 1230 4.32E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2774 2838 3.26E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.740 1005 1149 1.0E-15 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.740 864 997 5.0E-13 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 866 992 4.06E-25 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 34 176 7.21E-23 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49401 584 721 3.23E-23 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1453 1523 6.28E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 1740 1801 4.32E-6 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2026 2090 1.06E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2306 2368 1.92E-5 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 SUPERFAMILY SSF49478 2492 2558 1.57E-7 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1533 1627 4.3E-27 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2853 2946 8.3E-28 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2664 2757 4.9E-25 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2107 2201 1.1E-23 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2202 2291 1.2E-25 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2292 2382 5.3E-26 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2011 2106 3.0E-26 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2572 2663 3.4E-23 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1248 1344 2.8E-25 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2480 2571 1.7E-26 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2758 2852 1.5E-26 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1819 1913 3.9E-24 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1440 1532 2.3E-26 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 3038 3193 6.9E-26 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2947 3037 2.0E-25 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1727 1818 9.7E-23 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1345 1439 5.6E-25 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 2383 2479 1.6E-27 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1914 2010 1.3E-24 T 29-03-2018 CSW12_RS26580 945032594a329342e569957dd0014944 3226 Gene3D G3DSA:2.60.40.810 1628 1726 2.6E-25 T 29-03-2018 CSW12_RS07010 b70a4995cd219ec428edd28261b28d71 353 PIRSF PIRSF021350 1 353 1.0E-137 T 29-03-2018 IPR008308 Uncharacterised conserved protein UCP021350 CSW12_RS07010 b70a4995cd219ec428edd28261b28d71 353 Gene3D G3DSA:1.10.10.10 4 103 2.0E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07010 b70a4995cd219ec428edd28261b28d71 353 Gene3D G3DSA:1.10.10.10 163 294 0.4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07010 b70a4995cd219ec428edd28261b28d71 353 Pfam PF14493 Helix-turn-helix domain 257 344 3.2E-23 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CSW12_RS30505 eac04d2579feba70a5c7e2a5e267e284 165 Gene3D G3DSA:1.10.3100.10 1 165 2.1E-22 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS30505 eac04d2579feba70a5c7e2a5e267e284 165 SUPERFAMILY SSF47413 2 72 1.84E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS30505 eac04d2579feba70a5c7e2a5e267e284 165 SMART SM00530 7 68 8.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30505 eac04d2579feba70a5c7e2a5e267e284 165 Pfam PF01381 Helix-turn-helix 9 68 9.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29740 eac04d2579feba70a5c7e2a5e267e284 165 Gene3D G3DSA:1.10.3100.10 1 165 2.1E-22 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS29740 eac04d2579feba70a5c7e2a5e267e284 165 SUPERFAMILY SSF47413 2 72 1.84E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS29740 eac04d2579feba70a5c7e2a5e267e284 165 SMART SM00530 7 68 8.5E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29740 eac04d2579feba70a5c7e2a5e267e284 165 Pfam PF01381 Helix-turn-helix 9 68 9.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 PIRSF PIRSF036979 10 317 1.6E-60 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 SUPERFAMILY SSF52768 29 313 2.34E-74 T 29-03-2018 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 Gene3D G3DSA:3.40.800.10 23 317 2.2E-75 T 29-03-2018 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 Pfam PF00491 Arginase family 37 311 1.6E-71 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 PRINTS PR00116 Arginase signature 123 138 2.4E-10 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 PRINTS PR00116 Arginase signature 238 267 2.4E-10 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 PRINTS PR00116 Arginase signature 273 287 2.4E-10 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 TIGRFAM TIGR01227 hutG: formimidoylglutamase 10 311 4.0E-85 T 29-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CSW12_RS09505 c1567726da9882d8cfd2b68a61a455e3 323 ProSitePatterns PS01053 Arginase family signature. 241 262 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.40.120.10 156 262 2.6E-25 T 29-03-2018 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF53738 158 256 3.26E-26 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 1.5E-35 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 6.2E-16 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF53738 3 180 4.32E-46 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.3E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 2.3E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 2.3E-12 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.40.120.10 1 153 1.0E-44 T 29-03-2018 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.30.310.50 374 446 2.0E-22 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 1.8E-188 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.593 T 29-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 5.1E-16 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF55957 357 446 1.31E-26 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Gene3D G3DSA:3.40.120.10 263 373 5.3E-35 T 29-03-2018 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 SUPERFAMILY SSF53738 257 365 1.88E-33 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS28280 492c74d486427a2c860f23f081af342b 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 1.8E-43 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 1.5E-88 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 Gene3D G3DSA:1.10.601.10 2 105 7.9E-32 T 29-03-2018 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 85 93 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 220 235 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 61 74 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 203 215 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 PRINTS PR00046 Major sigma-70 factor signature 235 246 1.5E-11 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 SUPERFAMILY SSF88659 171 250 3.18E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 249 9.7E-39 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 Pfam PF04542 Sigma-70 region 2 38 105 4.2E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 PIRSF PIRSF000770 10 252 3.1E-35 T 29-03-2018 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 250 9.2E-118 T 29-03-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 Pfam PF04539 Sigma-70 region 3 115 184 1.5E-14 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 SUPERFAMILY SSF88659 109 184 5.67E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 Pfam PF04545 Sigma-70, region 4 199 247 2.3E-15 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 Gene3D G3DSA:1.10.10.10 106 158 7.1E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 Gene3D G3DSA:1.10.10.10 190 250 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 SUPERFAMILY SSF88946 6 105 7.98E-34 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07310 1df9d779279633f438bfd41efb634b79 252 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07230 09fe5d43b6ae644159b2262d995301e6 246 Pfam PF13115 YtkA-like 29 112 3.3E-15 T 29-03-2018 IPR032693 YtkA-like domain CSW12_RS07230 09fe5d43b6ae644159b2262d995301e6 246 Pfam PF13115 YtkA-like 156 229 1.2E-10 T 29-03-2018 IPR032693 YtkA-like domain CSW12_RS07230 09fe5d43b6ae644159b2262d995301e6 246 Gene3D G3DSA:2.60.40.10 147 246 1.0E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS07230 09fe5d43b6ae644159b2262d995301e6 246 Gene3D G3DSA:2.60.40.10 27 128 4.6E-5 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 Gene3D G3DSA:3.20.20.70 1 409 1.2E-101 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 Pfam PF00682 HMGL-like 4 272 1.3E-91 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 SMART SM00917 368 499 1.1E-30 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 506 41.015 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 SUPERFAMILY SSF51569 1 290 3.22E-91 T 29-03-2018 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 494 1.6E-207 T 29-03-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 497 1.6E-35 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 29-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS06580 1e1cec6366ca3fe5d15024ceccb7ce83 506 SUPERFAMILY SSF110921 397 496 1.96E-18 T 29-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 Pfam PF00005 ABC transporter 22 169 2.3E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 SMART SM00382 30 218 4.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 SUPERFAMILY SSF55021 249 340 8.81E-21 T 29-03-2018 CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 Pfam PF09383 NIL domain 265 337 3.5E-18 T 29-03-2018 IPR018449 NIL domain CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 Gene3D G3DSA:3.30.70.260 260 340 2.4E-24 T 29-03-2018 CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 Gene3D G3DSA:3.40.50.300 1 259 2.2E-79 T 29-03-2018 CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 SUPERFAMILY SSF52540 1 240 1.69E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS24740 553fa308328b991a038888ddd66b57f1 341 SMART SM00930 263 338 7.1E-26 T 29-03-2018 IPR018449 NIL domain CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.8E-51 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 SUPERFAMILY SSF74731 2 116 1.2E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 Gene3D G3DSA:1.10.1900.20 55 116 1.2E-29 T 29-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 Pfam PF00453 Ribosomal protein L20 3 109 1.2E-50 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.5E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.5E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.5E-41 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 4.0E-14 T 29-03-2018 CSW12_RS22480 61ae229658a51ef01d55a09302983729 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.563 T 29-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS06785 395c1ed0de6ec01d5e76ebb76338348c 235 Pfam PF13610 DDE domain 74 212 3.6E-50 T 29-03-2018 IPR032874 DDE domain CSW12_RS06785 395c1ed0de6ec01d5e76ebb76338348c 235 SUPERFAMILY SSF53098 70 191 2.12E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS06785 395c1ed0de6ec01d5e76ebb76338348c 235 Gene3D G3DSA:3.30.420.10 65 214 6.8E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS26150 917bf3c2d47adb88f1b5561a6f37a907 233 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 30 231 1.2E-69 T 29-03-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CSW12_RS26150 917bf3c2d47adb88f1b5561a6f37a907 233 Pfam PF13614 AAA domain 61 191 6.8E-15 T 29-03-2018 IPR025669 AAA domain CSW12_RS26150 917bf3c2d47adb88f1b5561a6f37a907 233 Gene3D G3DSA:3.40.50.300 12 228 6.6E-35 T 29-03-2018 CSW12_RS26150 917bf3c2d47adb88f1b5561a6f37a907 233 SUPERFAMILY SSF52540 50 226 3.41E-41 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11610 c9cdef4b5b84d2b2062b96a4d2e8417f 343 Gene3D G3DSA:3.50.30.60 171 340 2.5E-51 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS11610 c9cdef4b5b84d2b2062b96a4d2e8417f 343 PIRSF PIRSF028757 2 343 5.5E-68 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS11610 c9cdef4b5b84d2b2062b96a4d2e8417f 343 Gene3D G3DSA:3.40.50.10740 1 170 9.7E-47 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CSW12_RS11610 c9cdef4b5b84d2b2062b96a4d2e8417f 343 SUPERFAMILY SSF141986 174 334 1.24E-26 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS11610 c9cdef4b5b84d2b2062b96a4d2e8417f 343 Pfam PF02016 LD-carboxypeptidase 14 328 6.8E-71 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS11610 c9cdef4b5b84d2b2062b96a4d2e8417f 343 SUPERFAMILY SSF52317 2 169 2.11E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 SUPERFAMILY SSF53901 4 251 3.84E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 SMART SM00825 Beta-ketoacyl synthase 6 412 9.5E-16 T 29-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 9.3E-40 T 29-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 Gene3D G3DSA:3.40.47.10 1 258 1.1E-80 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 PIRSF PIRSF000447 1 412 2.5E-183 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 SUPERFAMILY SSF53901 214 411 6.11E-77 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 4.5E-198 T 29-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 Gene3D G3DSA:3.40.47.10 262 412 2.9E-54 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05410 9a7085a5d7ec7d35c4f794c277beded5 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 5.6E-62 T 29-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00097 Anthranilate synthase component II signature 55 64 1.2E-5 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00097 Anthranilate synthase component II signature 170 183 1.2E-5 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00097 Anthranilate synthase component II signature 82 93 1.2E-5 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Pfam PF02540 NAD synthase 212 285 5.2E-6 T 29-03-2018 IPR022310 NAD/GMP synthase CSW12_RS28860 734ab43b40af670089e31454fd246294 515 SUPERFAMILY SSF52402 190 408 5.95E-63 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 52 66 9.2E-7 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 9.2E-7 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 11 25 9.2E-7 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 8 515 55.661 T 29-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Gene3D G3DSA:3.40.50.620 226 383 6.9E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Gene3D G3DSA:3.40.50.880 6 225 9.3E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Pfam PF00958 GMP synthase C terminal domain 423 514 1.8E-44 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 515 1.2E-157 T 29-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 SUPERFAMILY SSF52317 6 230 1.7E-63 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 55 64 6.8E-8 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 6.8E-8 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 6.8E-8 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 11 197 8.9E-85 T 29-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 SUPERFAMILY SSF54810 395 515 4.05E-51 T 29-03-2018 CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Pfam PF00117 Glutamine amidotransferase class-I 13 192 6.0E-46 T 29-03-2018 IPR017926 Glutamine amidotransferase CSW12_RS28860 734ab43b40af670089e31454fd246294 515 Gene3D G3DSA:3.30.300.10 391 515 2.5E-53 T 29-03-2018 CSW12_RS08720 0abe6515b3f32aceb04275669cced610 93 Pfam PF04456 Protein of unknown function (DUF503) 3 87 1.5E-29 T 29-03-2018 IPR007546 Protein of unknown function DUF503 CSW12_RS08720 0abe6515b3f32aceb04275669cced610 93 Gene3D G3DSA:3.30.70.1120 2 92 2.5E-30 T 29-03-2018 CSW12_RS08720 0abe6515b3f32aceb04275669cced610 93 SUPERFAMILY SSF103007 1 93 7.32E-32 T 29-03-2018 IPR007546 Protein of unknown function DUF503 CSW12_RS28105 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 29-03-2018 CSW12_RS28105 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.778 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28105 7daf4c47f7f7eb87b15e0b26d32f1de9 37 SUPERFAMILY SSF57840 1 37 6.41E-17 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28105 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28105 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Pfam PF00444 Ribosomal protein L36 1 37 5.7E-19 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28105 7daf4c47f7f7eb87b15e0b26d32f1de9 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.2E-24 T 29-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 SUPERFAMILY SSF47413 1 60 5.55E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 Gene3D G3DSA:3.40.50.2300 164 325 1.9E-37 T 29-03-2018 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 SMART SM00354 1 71 5.4E-33 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 Gene3D G3DSA:3.40.50.2300 58 163 4.7E-21 T 29-03-2018 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 321 8.4E-33 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.7E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.7E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.2E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 SUPERFAMILY SSF53822 61 325 5.14E-61 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS28505 671561d5cfde6cea0eb9c0ba645ddc33 325 Gene3D G3DSA:1.10.260.40 3 57 1.7E-20 T 29-03-2018 CSW12_RS25740 404eba17d414a6109360dd174b21089f 245 SUPERFAMILY SSF88713 40 229 1.01E-51 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS25740 404eba17d414a6109360dd174b21089f 245 Pfam PF01522 Polysaccharide deacetylase 42 164 6.1E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS25740 404eba17d414a6109360dd174b21089f 245 Gene3D G3DSA:3.20.20.370 15 228 2.5E-44 T 29-03-2018 CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 SUPERFAMILY SSF56176 352 431 2.26E-15 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF03471 Transporter associated domain 356 430 2.3E-15 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 SUPERFAMILY SSF54631 204 341 7.33E-30 T 29-03-2018 CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 SMART SM01091 354 431 1.3E-18 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF01595 Domain of unknown function DUF21 8 201 3.3E-51 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF00571 CBS domain 288 338 1.1E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 Pfam PF00571 CBS domain 218 270 0.0011 T 29-03-2018 IPR000644 CBS domain CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 Gene3D G3DSA:3.30.465.10 345 431 1.5E-19 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS01755 ef3ac34f0a0669b9c1d881fc74301053 432 Gene3D G3DSA:3.10.580.10 195 344 1.1E-29 T 29-03-2018 CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 SUPERFAMILY SSF55658 1 56 6.98E-18 T 29-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.2E-50 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 5.3E-30 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.086 T 29-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 Gene3D G3DSA:3.10.430.100 63 147 2.3E-31 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 SUPERFAMILY SSF55653 57 147 3.66E-28 T 29-03-2018 IPR020069 Ribosomal protein L9, C-terminal CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 Gene3D G3DSA:3.40.5.10 1 49 2.0E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27210 2ae912f391671dfc7b151f15508ce296 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 9.4E-22 T 29-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 PIRSF PIRSF026579 1 178 2.9E-96 T 29-03-2018 IPR014213 Sporulation stage V, protein T CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 3.1E-94 T 29-03-2018 IPR014213 Sporulation stage V, protein T CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 4.3E-45 T 29-03-2018 CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 29-03-2018 CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 SMART SM00966 8 52 1.1E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 Gene3D G3DSA:2.10.260.10 1 49 2.5E-20 T 29-03-2018 CSW12_RS27615 6eb3963e4ca89528853eb2867aab7767 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 Gene3D G3DSA:3.40.50.10800 112 237 5.9E-25 T 29-03-2018 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 Pfam PF02445 Quinolinate synthetase A protein 29 366 9.0E-107 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 Gene3D G3DSA:3.40.50.10800 238 346 1.1E-26 T 29-03-2018 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 SUPERFAMILY SSF142754 34 366 8.24E-98 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 21 366 1.2E-116 T 29-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 Hamap MF_00569 Quinolinate synthase A [nadA]. 22 367 56.788 T 29-03-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CSW12_RS21775 f34f1fbb741721defaf6e843e26ac30e 368 Gene3D G3DSA:3.40.50.10800 21 107 7.2E-17 T 29-03-2018 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Pfam PF04851 Type III restriction enzyme, res subunit 16 115 5.0E-10 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Gene3D G3DSA:3.40.50.300 416 588 2.7E-32 T 29-03-2018 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 SMART SM00490 459 545 2.9E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 SMART SM00487 9 425 1.4E-24 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 655 0.0 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 SUPERFAMILY SSF52540 32 80 3.38E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 SUPERFAMILY SSF52540 469 593 3.38E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Pfam PF12344 Ultra-violet resistance protein B 551 592 1.4E-22 T 29-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 657 44.894 T 29-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 SUPERFAMILY SSF52540 4 414 7.76E-143 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Pfam PF00271 Helicase conserved C-terminal domain 440 544 6.0E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 SUPERFAMILY SSF46600 613 656 5.1E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Gene3D G3DSA:4.10.860.10 595 658 2.6E-15 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Gene3D G3DSA:3.40.50.300 10 415 4.4E-31 T 29-03-2018 CSW12_RS25525 933db9e2f41c6d2cefa7bf946bd66dba 658 Pfam PF02151 UvrB/uvrC motif 622 656 4.8E-9 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 Pfam PF09397 Ftsk gamma domain 726 785 2.5E-30 T 29-03-2018 IPR018541 FtsK gamma domain CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 Gene3D G3DSA:1.10.10.10 729 779 3.8E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 SUPERFAMILY SSF52540 405 700 1.95E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 Gene3D G3DSA:3.40.50.300 208 728 1.2E-57 T 29-03-2018 CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 SMART SM00843 723 788 6.0E-40 T 29-03-2018 IPR018541 FtsK gamma domain CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 SMART SM00382 467 649 0.0016 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 SUPERFAMILY SSF46785 724 786 5.98E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08805 32d374248b421b145b54fec724c8f770 793 Pfam PF01580 FtsK/SpoIIIE family 432 628 2.5E-65 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS09530 13fe6c4933b2823fdecfcbfb53eb9671 493 Pfam PF00474 Sodium:solute symporter family 34 432 3.0E-109 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS09530 13fe6c4933b2823fdecfcbfb53eb9671 493 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 432 1.1E-101 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS09530 13fe6c4933b2823fdecfcbfb53eb9671 493 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 5 487 2.9E-223 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 7.8E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 7.8E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 7.8E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 7.8E-11 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 SUPERFAMILY SSF53474 11 277 2.53E-63 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 Gene3D G3DSA:3.40.50.1820 3 277 1.1E-53 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 1.8E-11 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS12150 080de284bba69aaeef14902615c7a832 278 Pfam PF00561 alpha/beta hydrolase fold 25 258 1.8E-31 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 Gene3D G3DSA:3.30.450.20 324 484 6.7E-28 T 29-03-2018 CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SMART SM00091 356 422 1.2E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 476 637 5.7E-40 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 355 474 9.7E-18 T 29-03-2018 IPR000014 PAS domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 Pfam PF13426 PAS domain 366 467 1.3E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SMART SM00086 427 468 9.2E-4 T 29-03-2018 IPR001610 PAC motif CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SUPERFAMILY SSF141868 655 904 1.31E-83 T 29-03-2018 IPR001633 EAL domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 Pfam PF00990 Diguanylate cyclase, GGDEF domain 479 635 1.9E-49 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SUPERFAMILY SSF55785 344 466 1.1E-21 T 29-03-2018 IPR000014 PAS domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SMART SM00052 650 896 1.6E-106 T 29-03-2018 IPR001633 EAL domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SUPERFAMILY SSF55073 484 641 5.96E-47 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 SMART SM00267 468 640 3.9E-61 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 Gene3D G3DSA:3.20.20.450 648 908 6.8E-92 T 29-03-2018 IPR001633 EAL domain CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 Gene3D G3DSA:3.30.70.270 485 647 1.1E-57 T 29-03-2018 CSW12_RS26280 d84f50b25eced0067559267c2f5f65c0 909 Pfam PF00563 EAL domain 656 891 4.8E-67 T 29-03-2018 IPR001633 EAL domain CSW12_RS03150 5a0f374f758e16f47868abc0be0fa17f 532 Pfam PF04471 Restriction endonuclease 402 517 3.8E-28 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CSW12_RS03150 5a0f374f758e16f47868abc0be0fa17f 532 Gene3D G3DSA:3.40.1350.10 391 519 2.9E-26 T 29-03-2018 CSW12_RS03150 5a0f374f758e16f47868abc0be0fa17f 532 SUPERFAMILY SSF52980 406 522 2.47E-18 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 Gene3D G3DSA:3.40.640.10 88 356 1.0E-55 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 384 403 1.0E-19 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 79 98 1.0E-19 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 12 31 1.0E-19 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 100 118 1.0E-19 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 341 356 1.0E-19 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 119 138 1.0E-19 T 29-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 Gene3D G3DSA:1.20.1340.10 7 87 3.7E-18 T 29-03-2018 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 SUPERFAMILY SSF53383 8 471 8.66E-129 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 50 402 1.9E-73 T 29-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CSW12_RS14050 decfb506744b6d355659b2fa0eb3f189 484 Gene3D G3DSA:3.90.1150.10 357 472 2.6E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 Pfam PF07690 Major Facilitator Superfamily 13 205 2.8E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 Pfam PF07690 Major Facilitator Superfamily 213 380 5.6E-17 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.5E-6 T 29-03-2018 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.5E-6 T 29-03-2018 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 358 378 1.5E-6 T 29-03-2018 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.5E-6 T 29-03-2018 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 Gene3D G3DSA:1.20.1250.20 5 197 2.6E-32 T 29-03-2018 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 Gene3D G3DSA:1.20.1250.20 198 385 9.5E-29 T 29-03-2018 CSW12_RS03045 2857df9fa50836cf0d76aa1b55a8bc7b 393 SUPERFAMILY SSF103473 7 384 9.94E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS09160 08928218e6305c71c0756036833827b4 297 Pfam PF00149 Calcineurin-like phosphoesterase 64 229 1.4E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS09160 08928218e6305c71c0756036833827b4 297 Gene3D G3DSA:3.60.21.10 62 280 3.6E-26 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS09160 08928218e6305c71c0756036833827b4 297 SUPERFAMILY SSF56300 64 291 2.67E-37 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 Pfam PF07690 Major Facilitator Superfamily 9 402 4.9E-59 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 Gene3D G3DSA:1.20.1250.20 244 479 1.9E-33 T 29-03-2018 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 SUPERFAMILY SSF103473 2 194 6.41E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 SUPERFAMILY SSF103473 445 472 6.41E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 SUPERFAMILY SSF103473 241 411 6.41E-72 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 8 32 3.2E-6 T 29-03-2018 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 129 153 3.2E-6 T 29-03-2018 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 67 89 3.2E-6 T 29-03-2018 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 392 411 3.2E-6 T 29-03-2018 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 Gene3D G3DSA:1.20.1250.20 1 191 1.8E-39 T 29-03-2018 CSW12_RS23230 3b832dbe2f4f70cce4e3cf15e1b2ea56 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 6 414 6.6E-69 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 61 72 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 SUPERFAMILY SSF52440 1 94 2.59E-28 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 1 296 35.648 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 Pfam PF07478 D-ala D-ala ligase C-terminus 104 293 1.3E-52 T 29-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 SUPERFAMILY SSF56059 94 292 1.77E-49 T 29-03-2018 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 SMART SM01209 93 263 0.0015 T 29-03-2018 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 2 295 4.3E-89 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 Pfam PF01820 D-ala D-ala ligase N-terminus 2 84 5.8E-22 T 29-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 PIRSF PIRSF039102 1 48 1.1E-11 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 PIRSF PIRSF039102 41 303 7.5E-102 T 29-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 Gene3D G3DSA:3.30.470.20 164 304 7.7E-39 T 29-03-2018 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 Gene3D G3DSA:3.40.50.20 1 95 8.6E-35 T 29-03-2018 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 Gene3D G3DSA:3.30.1490.20 96 163 4.1E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS14680 c55da336e4149d619534b259c63aeb24 304 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 239 266 - T 29-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Gene3D G3DSA:4.10.860.10 174 234 1.8E-12 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.327 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Gene3D G3DSA:3.40.1440.10 1 98 1.0E-25 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 SUPERFAMILY SSF82771 14 97 2.62E-22 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Pfam PF01541 GIY-YIG catalytic domain 16 90 5.7E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 SUPERFAMILY SSF47781 500 591 6.04E-21 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 SMART SM00465 15 95 8.3E-21 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Pfam PF02151 UvrB/uvrC motif 196 229 1.0E-8 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Gene3D G3DSA:1.10.150.20 535 593 7.1E-12 T 29-03-2018 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 570 3.2E-211 T 29-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 SUPERFAMILY SSF46600 182 235 1.31E-13 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS22195 f83ea614f8492170b9dcf9a2aa3d1a97 594 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 372 523 1.1E-54 T 29-03-2018 IPR001162 UvrC family homology region CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 430 28.527 T 29-03-2018 IPR026593 Protein translocase subunit SecY CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 9.0E-97 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 426 4.9E-143 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 29-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 Gene3D G3DSA:1.10.3370.10 1 434 1.5E-152 T 29-03-2018 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 Pfam PF00344 SecY translocase 68 414 7.5E-110 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 SUPERFAMILY SSF103491 1 421 9.02E-125 T 29-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS14010 3fe3eaff1955b48edbd2eb17b56269f0 434 PIRSF PIRSF004557 1 434 2.2E-124 T 29-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS06400 4d0fdb155fca348888af3f62e1a658ba 79 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 79 45.497 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CSW12_RS06400 4d0fdb155fca348888af3f62e1a658ba 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 9.6E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS06400 4d0fdb155fca348888af3f62e1a658ba 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 5 77 1.4E-35 T 29-03-2018 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13 CSW12_RS06400 4d0fdb155fca348888af3f62e1a658ba 79 Gene3D G3DSA:1.10.1200.10 2 79 3.3E-9 T 29-03-2018 CSW12_RS06400 4d0fdb155fca348888af3f62e1a658ba 79 SUPERFAMILY SSF47336 2 77 2.36E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS00890 3bcba6fe7071423403130388d356df0d 292 Gene3D G3DSA:3.30.420.40 2 118 2.0E-24 T 29-03-2018 CSW12_RS00890 3bcba6fe7071423403130388d356df0d 292 Pfam PF00480 ROK family 4 285 1.9E-47 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CSW12_RS00890 3bcba6fe7071423403130388d356df0d 292 SUPERFAMILY SSF53067 3 291 1.89E-59 T 29-03-2018 CSW12_RS00890 3bcba6fe7071423403130388d356df0d 292 Gene3D G3DSA:3.30.420.40 119 292 6.0E-48 T 29-03-2018 CSW12_RS03980 368ab963027b40b689c69d684b63f8ce 295 SUPERFAMILY SSF103481 186 278 1.83E-14 T 29-03-2018 CSW12_RS03980 368ab963027b40b689c69d684b63f8ce 295 SUPERFAMILY SSF103481 40 139 2.62E-9 T 29-03-2018 CSW12_RS03980 368ab963027b40b689c69d684b63f8ce 295 Pfam PF00892 EamA-like transporter family 146 277 4.5E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS03980 368ab963027b40b689c69d684b63f8ce 295 Pfam PF00892 EamA-like transporter family 6 136 1.4E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS08255 153b80a4c77e9645467a855282bee919 224 SUPERFAMILY SSF51419 2 222 8.43E-68 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS08255 153b80a4c77e9645467a855282bee919 224 PIRSF PIRSF004848 1 224 3.4E-63 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CSW12_RS08255 153b80a4c77e9645467a855282bee919 224 Pfam PF01168 Alanine racemase, N-terminal domain 13 222 2.1E-17 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS08255 153b80a4c77e9645467a855282bee919 224 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 3 222 2.8E-49 T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CSW12_RS08255 153b80a4c77e9645467a855282bee919 224 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 29-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CSW12_RS08255 153b80a4c77e9645467a855282bee919 224 Gene3D G3DSA:3.20.20.10 1 224 5.1E-46 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 45 7.2E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 319 325 7.2E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 4 16 7.2E-8 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 SUPERFAMILY SSF51905 3 218 1.64E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 SUPERFAMILY SSF51905 327 386 1.64E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 Gene3D G3DSA:3.50.50.60 2 84 3.5E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 Gene3D G3DSA:3.50.50.60 318 389 4.0E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 SUPERFAMILY SSF54373 270 326 1.57E-11 T 29-03-2018 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 Gene3D G3DSA:3.30.9.10 86 159 8.2E-9 T 29-03-2018 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 Pfam PF01266 FAD dependent oxidoreductase 5 365 5.2E-68 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS13505 79fea0fb7782e60f0eb37aafbd6d406c 391 Gene3D G3DSA:3.30.9.10 160 317 8.8E-30 T 29-03-2018 CSW12_RS20820 7e24bd825329a17d603bc248ee07ac81 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 204 218 - T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CSW12_RS20820 7e24bd825329a17d603bc248ee07ac81 347 Gene3D G3DSA:3.30.450.90 2 107 2.2E-29 T 29-03-2018 CSW12_RS20820 7e24bd825329a17d603bc248ee07ac81 347 SUPERFAMILY SSF52540 5 283 7.16E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20820 7e24bd825329a17d603bc248ee07ac81 347 Pfam PF00437 Type II/IV secretion system protein 12 275 3.1E-71 T 29-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CSW12_RS20820 7e24bd825329a17d603bc248ee07ac81 347 Gene3D G3DSA:3.40.50.300 109 337 7.7E-34 T 29-03-2018 CSW12_RS20820 7e24bd825329a17d603bc248ee07ac81 347 SMART SM00382 136 265 8.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 483 36.768 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 SUPERFAMILY SSF63418 1 97 1.11E-25 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Gene3D G3DSA:3.90.190.20 337 491 3.0E-50 T 29-03-2018 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Pfam PF08245 Mur ligase middle domain 106 311 2.0E-56 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Pfam PF01225 Mur ligase family, catalytic domain 22 93 1.1E-13 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 SUPERFAMILY SSF53244 332 486 1.7E-50 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Gene3D G3DSA:3.40.1390.10 1 96 1.0E-26 T 29-03-2018 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 SUPERFAMILY SSF53623 97 331 3.4E-76 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Gene3D G3DSA:3.40.1190.10 97 336 8.1E-66 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 417 1.1E-22 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS08185 76babebfacd72a757dd7eee946f8bd86 491 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 483 1.1E-171 T 29-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CSW12_RS07845 5a038ea9977f6e5577a99ef6785d6e71 221 Gene3D G3DSA:3.40.50.720 6 138 2.3E-24 T 29-03-2018 CSW12_RS07845 5a038ea9977f6e5577a99ef6785d6e71 221 Pfam PF02254 TrkA-N domain 8 123 1.2E-29 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CSW12_RS07845 5a038ea9977f6e5577a99ef6785d6e71 221 SUPERFAMILY SSF116726 135 220 2.62E-21 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS07845 5a038ea9977f6e5577a99ef6785d6e71 221 Gene3D G3DSA:3.30.70.1450 139 219 2.8E-21 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS07845 5a038ea9977f6e5577a99ef6785d6e71 221 Pfam PF02080 TrkA-C domain 153 219 2.3E-17 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS07845 5a038ea9977f6e5577a99ef6785d6e71 221 SUPERFAMILY SSF51735 7 137 1.64E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07735 19f3e9cbb51a4599592afedbcfafc5fd 166 Gene3D G3DSA:2.60.40.1170 33 152 1.8E-6 T 29-03-2018 CSW12_RS16865 902460ba75302ba8dfcad561bbf489d7 485 Pfam PF11954 Domain of unknown function (DUF3471) 385 481 2.6E-19 T 29-03-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal CSW12_RS16865 902460ba75302ba8dfcad561bbf489d7 485 Gene3D G3DSA:3.40.710.10 10 354 4.3E-84 T 29-03-2018 CSW12_RS16865 902460ba75302ba8dfcad561bbf489d7 485 Pfam PF00144 Beta-lactamase 13 337 6.1E-62 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS16865 902460ba75302ba8dfcad561bbf489d7 485 SUPERFAMILY SSF56601 9 352 1.41E-85 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 Pfam PF00266 Aminotransferase class-V 4 348 1.3E-51 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 357 3.4E-159 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 50.476 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 Gene3D G3DSA:3.90.1150.10 258 358 3.5E-36 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 Gene3D G3DSA:3.40.640.10 16 257 2.6E-27 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 SUPERFAMILY SSF53383 1 356 2.08E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS11585 a336cd9a6f6d50a3eee26630e3f3c365 360 PIRSF PIRSF000525 1 360 8.9E-155 T 29-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 550 0.0 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 PIRSF PIRSF001423 1 552 1.8E-303 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 Pfam PF17392 Urocanase C-terminal domain 348 542 9.9E-96 T 29-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 Gene3D G3DSA:3.40.1770.10 6 149 6.6E-30 T 29-03-2018 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 Gene3D G3DSA:3.40.1770.10 192 551 1.3E-167 T 29-03-2018 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 Hamap MF_00577 Urocanate hydratase [hutU]. 4 552 51.607 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 ProSitePatterns PS01233 Urocanase signature. 438 453 - T 29-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 Pfam PF01175 Urocanase Rossmann-like domain 137 345 1.3E-92 T 29-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 SUPERFAMILY SSF111326 5 551 1.05E-266 T 29-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09495 164d1f27e331cfb9eaeff2574177f0dc 552 Pfam PF17391 Urocanase N-terminal domain 8 134 2.9E-63 T 29-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 Gene3D G3DSA:3.40.630.10 2 293 1.9E-33 T 29-03-2018 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PIRSF PIRSF016599 2 487 1.6E-190 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 SUPERFAMILY SSF55031 213 302 3.59E-5 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 9 483 8.4E-178 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 Pfam PF01546 Peptidase family M20/M25/M40 74 472 7.5E-19 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 SUPERFAMILY SSF53187 13 183 1.63E-53 T 29-03-2018 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 SUPERFAMILY SSF53187 399 482 1.63E-53 T 29-03-2018 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 Pfam PF07687 Peptidase dimerisation domain 213 292 3.4E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 Gene3D G3DSA:3.40.630.10 330 487 4.1E-10 T 29-03-2018 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 452 474 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 136 153 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 102 120 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 81 100 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 160 178 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 430 446 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 207 224 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 365 383 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS15605 47f551b7169c3650b339833a067d4976 489 PRINTS PR00934 X-His dipeptidase (M25) signature 252 271 2.5E-49 T 29-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CSW12_RS10535 9d3beca5a0627872287af30edc3d7de5 178 SUPERFAMILY SSF55729 1 170 8.07E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS10535 9d3beca5a0627872287af30edc3d7de5 178 Pfam PF13302 Acetyltransferase (GNAT) domain 7 144 5.0E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS10535 9d3beca5a0627872287af30edc3d7de5 178 Gene3D G3DSA:3.40.630.30 1 176 3.4E-21 T 29-03-2018 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 SUPERFAMILY SSF81799 113 214 3.27E-36 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 Gene3D G3DSA:1.10.150.170 111 207 1.0E-38 T 29-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.323 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 309 7.0E-130 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 Pfam PF01795 MraW methylase family 2 310 2.7E-134 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 PIRSF PIRSF004486 1 310 2.2E-110 T 29-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 Gene3D G3DSA:3.40.50.150 208 266 3.2E-5 T 29-03-2018 CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 SUPERFAMILY SSF53335 4 112 1.5E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS08165 d59624b36b137c915e64ae919280fd08 310 SUPERFAMILY SSF53335 214 309 1.5E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 SUPERFAMILY SSF56024 301 500 2.92E-51 T 29-03-2018 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 SUPERFAMILY SSF56024 144 344 1.19E-49 T 29-03-2018 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 43 514 1.6E-187 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 Pfam PF13091 PLD-like domain 356 480 2.4E-28 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 Pfam PF13091 PLD-like domain 167 309 6.2E-11 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 Gene3D G3DSA:3.30.870.10 344 507 2.4E-32 T 29-03-2018 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 Hamap MF_01916 Cardiolipin synthase. 46 514 42.315 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 Gene3D G3DSA:3.30.870.10 142 325 1.5E-32 T 29-03-2018 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 Pfam PF13396 Phospholipase_D-nuclease N-terminal 57 93 1.6E-8 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 SMART SM00155 249 276 8.4E-5 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS05500 913654b4046f908e31ac86a9264f371a 514 SMART SM00155 427 454 4.2E-7 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS08245 95c12e1015aab78efd53586b2305ee83 93 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 4 76 1.6E-25 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CSW12_RS08245 95c12e1015aab78efd53586b2305ee83 93 SUPERFAMILY SSF50346 1 75 1.07E-14 T 29-03-2018 IPR011033 PRC-barrel-like CSW12_RS08245 95c12e1015aab78efd53586b2305ee83 93 Pfam PF05239 PRC-barrel domain 2 78 1.3E-13 T 29-03-2018 IPR027275 PRC-barrel domain CSW12_RS08245 95c12e1015aab78efd53586b2305ee83 93 Gene3D G3DSA:2.30.30.240 1 79 2.5E-16 T 29-03-2018 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 399 486 1.1E-20 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 1 497 7.1E-186 T 29-03-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 Gene3D G3DSA:3.30.1360.60 425 500 3.3E-26 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 SUPERFAMILY SSF55604 428 499 1.01E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 Pfam PF02378 Phosphotransferase system, EIIC 9 342 5.8E-79 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 Pfam PF00367 phosphotransferase system, EIIB 430 461 3.6E-13 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS01105 7bc4fa3d0df740201ed2b3dea3aa4d22 500 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 439 456 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 SUPERFAMILY SSF53720 16 460 7.59E-80 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 Gene3D G3DSA:1.20.1090.10 650 867 3.4E-65 T 29-03-2018 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 Gene3D G3DSA:3.40.309.10 241 412 8.6E-26 T 29-03-2018 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 Gene3D G3DSA:3.40.605.10 2 240 2.3E-29 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 Pfam PF00465 Iron-containing alcohol dehydrogenase 464 851 7.2E-121 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 PIRSF PIRSF000111 1 867 0.0 T 29-03-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 638 666 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 SUPERFAMILY SSF56796 455 866 4.06E-126 T 29-03-2018 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 Gene3D G3DSA:3.40.50.1970 437 649 1.9E-54 T 29-03-2018 CSW12_RS21490 26c3ef5f3331f8bd3a0009af516f69c0 867 Pfam PF00171 Aldehyde dehydrogenase family 13 407 8.0E-23 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 SUPERFAMILY SSF53850 4 273 1.37E-70 T 29-03-2018 CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 Gene3D G3DSA:3.40.190.10 171 276 5.2E-19 T 29-03-2018 CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 Gene3D G3DSA:3.40.190.10 40 170 9.8E-34 T 29-03-2018 CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 272 1.2E-59 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 74 87 - T 29-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 SMART SM00079 50 272 2.4E-6 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CSW12_RS01900 03c1a227f8439d3e02c222dc621dc60f 276 SMART SM00062 50 273 5.1E-84 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 Gene3D G3DSA:3.40.1010.10 1 126 5.7E-39 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 SUPERFAMILY SSF53790 1 246 9.03E-84 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 3.0E-102 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 2.6E-52 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS06710 836fc7bae1cb1dc5bf007f6b3fba7c27 258 Gene3D G3DSA:3.30.950.10 127 256 6.1E-43 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS19490 b51239b62a926705da88ac6f7829bd80 244 PIRSF PIRSF005426 1 244 2.8E-93 T 29-03-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 CSW12_RS19490 b51239b62a926705da88ac6f7829bd80 244 Pfam PF00881 Nitroreductase family 10 161 2.0E-20 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS19490 b51239b62a926705da88ac6f7829bd80 244 Gene3D G3DSA:3.40.109.10 1 244 1.1E-62 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS19490 b51239b62a926705da88ac6f7829bd80 244 SUPERFAMILY SSF55469 1 243 1.81E-71 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 SUPERFAMILY SSF160975 1372 1412 6.28E-6 T 29-03-2018 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Pfam PF11490 DNA polymerase III polC-type N-terminus II 96 205 6.3E-23 T 29-03-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 SMART SM00481 332 399 2.1E-26 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Gene3D G3DSA:3.20.20.140 601 792 4.0E-20 T 29-03-2018 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1433 450.084 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 SMART SM00479 417 583 2.8E-55 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 SUPERFAMILY SSF53098 417 873 1.25E-105 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Gene3D G3DSA:1.10.150.280 1369 1419 0.0014 T 29-03-2018 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Pfam PF02811 PHP domain 333 691 9.3E-52 T 29-03-2018 IPR004013 PHP domain GO:0003824 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Pfam PF14480 DNA polymerase III polC-type N-terminus I 10 80 1.6E-19 T 29-03-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Gene3D G3DSA:3.30.420.10 409 566 1.0E-43 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Gene3D G3DSA:2.40.50.140 216 317 3.0E-21 T 29-03-2018 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Pfam PF14579 Helix-hairpin-helix motif 1348 1424 2.0E-8 T 29-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Pfam PF00929 Exonuclease 419 573 7.7E-42 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 410 631 1.0E-64 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 823 1230 1.5E-94 T 29-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 Gene3D G3DSA:1.20.5.140 567 586 4.9E-12 T 29-03-2018 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 227 1433 0.0 T 29-03-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS08690 a234c66a263d86b4bef7d3d9ed8068e1 1433 SUPERFAMILY SSF50249 236 317 1.09E-9 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS07605 a3865247f15a55c5e1ca194597b48ebf 407 SUPERFAMILY SSF56059 89 319 8.25E-26 T 29-03-2018 CSW12_RS07605 a3865247f15a55c5e1ca194597b48ebf 407 Pfam PF13535 ATP-grasp domain 142 290 1.2E-9 T 29-03-2018 CSW12_RS07605 a3865247f15a55c5e1ca194597b48ebf 407 Gene3D G3DSA:3.30.1490.20 78 187 4.0E-7 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS07605 a3865247f15a55c5e1ca194597b48ebf 407 Gene3D G3DSA:3.30.470.20 188 379 1.0E-10 T 29-03-2018 CSW12_RS26375 468d9a5fb12277c966c17d12ba3dd9eb 147 Gene3D G3DSA:3.40.1400.10 1 147 2.8E-64 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CSW12_RS26375 468d9a5fb12277c966c17d12ba3dd9eb 147 SUPERFAMILY SSF89623 1 145 3.66E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CSW12_RS26375 468d9a5fb12277c966c17d12ba3dd9eb 147 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 7.9E-49 T 29-03-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 CSW12_RS26375 468d9a5fb12277c966c17d12ba3dd9eb 147 Pfam PF02502 Ribose/Galactose Isomerase 3 141 4.3E-54 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CSW12_RS26375 468d9a5fb12277c966c17d12ba3dd9eb 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 6.7E-60 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CSW12_RS26375 468d9a5fb12277c966c17d12ba3dd9eb 147 PIRSF PIRSF005384 1 147 2.5E-57 T 29-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Gene3D G3DSA:3.40.50.2300 674 772 5.8E-4 T 29-03-2018 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Gene3D G3DSA:1.10.1790.10 773 887 6.5E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 SUPERFAMILY SSF52540 98 322 5.51E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Gene3D G3DSA:3.40.50.300 62 291 5.1E-20 T 29-03-2018 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 SUPERFAMILY SSF63520 428 528 5.36E-23 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 175 190 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 SUPERFAMILY SSF63520 792 885 1.1E-15 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Pfam PF03610 PTS system fructose IIA component 541 653 6.4E-8 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Gene3D G3DSA:3.40.50.510 526 669 1.0E-24 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Gene3D G3DSA:1.10.1790.10 410 525 1.4E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 SUPERFAMILY SSF53062 539 660 5.76E-20 T 29-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 SUPERFAMILY SSF46785 16 61 8.14E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Pfam PF00874 PRD domain 799 884 3.3E-14 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Pfam PF00874 PRD domain 442 528 7.8E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Pfam PF00158 Sigma-54 interaction domain 83 244 5.2E-45 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 Gene3D G3DSA:1.10.10.10 1 61 4.7E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25745 4be3bac242c23fc55196c90f6c108238 891 SMART SM00382 103 252 4.8E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Gene3D G3DSA:3.30.930.10 224 533 1.2E-126 T 29-03-2018 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Gene3D G3DSA:3.30.54.20 149 190 3.0E-20 T 29-03-2018 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Gene3D G3DSA:3.40.50.800 534 640 7.5E-31 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Gene3D G3DSA:3.10.20.30 3 66 1.8E-18 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 SMART SM00863 173 222 6.0E-23 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Gene3D G3DSA:3.30.980.10 69 148 1.8E-26 T 29-03-2018 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 SUPERFAMILY SSF55186 67 244 1.83E-65 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 76 634 1.0E-233 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 222 3.4E-15 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 332 360 4.7E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 365 388 4.7E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 466 494 4.7E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 509 522 4.7E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 536 548 4.7E-53 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 530 8.0E-42 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 SUPERFAMILY SSF81271 6 65 3.49E-15 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 SUPERFAMILY SSF52954 529 638 1.16E-31 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 70 637 35.204 T 29-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Pfam PF03129 Anticodon binding domain 543 633 1.6E-21 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 SUPERFAMILY SSF55681 246 528 2.13E-97 T 29-03-2018 CSW12_RS16100 49710f367c1d941783019648782e9cf5 640 Pfam PF02824 TGS domain 7 65 1.3E-11 T 29-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CSW12_RS22800 1ca6927c5a33934390d15f708615d55a 277 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 33 273 4.0E-7 T 29-03-2018 CSW12_RS22800 1ca6927c5a33934390d15f708615d55a 277 Pfam PF12787 EcsC protein family 8 270 2.2E-57 T 29-03-2018 IPR024787 EcsC protein CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 Gene3D G3DSA:3.40.50.10360 12 188 3.9E-82 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 Hamap MF_00800 UPF0340 protein . 1 196 97.261 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 SUPERFAMILY SSF110710 12 190 1.54E-78 T 29-03-2018 CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 Pfam PF04260 Protein of unknown function (DUF436) 17 186 6.1E-79 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 18 190 4.0E-95 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 PIRSF PIRSF007510 8 189 2.3E-79 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CSW12_RS26370 7955c8602649ee7efbc0f25ca6509ab7 196 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 16 186 6.7E-76 T 29-03-2018 IPR006340 Protein of unknown function DUF436 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 SMART SM00959 7 49 3.1E-15 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 SUPERFAMILY SSF68912 4 49 1.1E-10 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 TIGRFAM TIGR00767 rho: transcription termination factor Rho 4 412 1.1E-204 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 361 2.5E-18 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 SUPERFAMILY SSF52540 91 369 6.64E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Gene3D G3DSA:3.40.50.300 113 365 2.0E-49 T 29-03-2018 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Pfam PF07498 Rho termination factor, N-terminal domain 8 49 4.5E-15 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 SUPERFAMILY SSF50249 51 114 3.48E-7 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Gene3D G3DSA:2.40.50.140 51 112 3.6E-28 T 29-03-2018 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 222.558 T 29-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 SMART SM00357 54 119 1.2E-19 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Gene3D G3DSA:1.10.720.10 2 45 4.6E-15 T 29-03-2018 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 Pfam PF07497 Rho termination factor, RNA-binding domain 53 126 2.3E-31 T 29-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CSW12_RS26455 079fb7631f2b5d33344d11484b27fa8a 423 SMART SM00382 168 353 1.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS23940 2a0e696baf9a32d8a193270461ed23bd 441 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 441 5.2E-138 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS23940 2a0e696baf9a32d8a193270461ed23bd 441 Pfam PF02447 GntP family permease 5 439 1.4E-145 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS23940 2a0e696baf9a32d8a193270461ed23bd 441 PIRSF PIRSF002746 1 441 5.0E-145 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 29-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 Gene3D G3DSA:3.40.50.720 7 98 2.1E-18 T 29-03-2018 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 SUPERFAMILY SSF51735 83 273 1.17E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 304 2.4E-19 T 29-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 SUPERFAMILY SSF52283 22 105 7.37E-21 T 29-03-2018 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 Gene3D G3DSA:3.40.50.720 99 275 1.8E-38 T 29-03-2018 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 94 272 5.8E-42 T 29-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 138 165 - T 29-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 SUPERFAMILY SSF55021 307 389 6.47E-16 T 29-03-2018 CSW12_RS11590 3981f67ab14fdf4b8003cab7301ce87b 390 Gene3D G3DSA:3.30.70.260 306 389 7.2E-14 T 29-03-2018 CSW12_RS15775 c10e4fd79b5bbb9badb07fe199ded4c9 202 SUPERFAMILY SSF53335 31 200 2.56E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS15775 c10e4fd79b5bbb9badb07fe199ded4c9 202 Gene3D G3DSA:3.40.50.150 25 195 5.7E-30 T 29-03-2018 CSW12_RS15775 c10e4fd79b5bbb9badb07fe199ded4c9 202 Pfam PF01596 O-methyltransferase 35 191 1.8E-25 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CSW12_RS22325 9a317754a8595bd5c38382ec397174a8 256 SMART SM00382 26 215 8.2E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS22325 9a317754a8595bd5c38382ec397174a8 256 SUPERFAMILY SSF52540 1 224 9.06E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22325 9a317754a8595bd5c38382ec397174a8 256 Gene3D G3DSA:3.40.50.300 1 245 2.0E-57 T 29-03-2018 CSW12_RS22325 9a317754a8595bd5c38382ec397174a8 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS22325 9a317754a8595bd5c38382ec397174a8 256 Pfam PF00005 ABC transporter 17 165 3.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 Gene3D G3DSA:3.40.50.970 359 558 9.6E-55 T 29-03-2018 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 Gene3D G3DSA:3.40.50.1220 202 358 5.7E-50 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 SUPERFAMILY SSF52467 203 367 8.44E-62 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 Gene3D G3DSA:3.40.50.970 12 197 3.2E-65 T 29-03-2018 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 208 342 6.2E-44 T 29-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 568 1.3E-254 T 29-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 SUPERFAMILY SSF52518 375 568 2.4E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 18 184 4.0E-59 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 545 1.2E-51 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS18610 f44a706e6f0a8a60edc2d81ccf54055d 573 SUPERFAMILY SSF52518 11 197 2.31E-64 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 Gene3D G3DSA:1.10.10.10 1 71 3.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 Gene3D G3DSA:3.30.1340.20 79 179 6.2E-40 T 29-03-2018 IPR004173 3H domain GO:0036094 CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 PIRSF PIRSF037847 9 180 8.5E-68 T 29-03-2018 IPR026043 Transcription repressor NadR CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 Pfam PF08279 HTH domain 14 66 2.4E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 SUPERFAMILY SSF46785 10 69 3.63E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 85 179 5.0E-50 T 29-03-2018 IPR004173 3H domain GO:0036094 CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 Pfam PF02829 3H domain 82 178 2.9E-36 T 29-03-2018 IPR004173 3H domain GO:0036094 CSW12_RS21795 3dd834ba020b15a7192152d07ac2f102 180 SUPERFAMILY SSF75500 77 179 5.1E-38 T 29-03-2018 IPR004173 3H domain GO:0036094 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 Gene3D G3DSA:3.40.720.10 21 477 2.3E-115 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 SUPERFAMILY SSF53649 28 475 6.28E-116 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 Pfam PF00245 Alkaline phosphatase 45 466 3.9E-88 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 Gene3D G3DSA:3.30.457.10 478 551 3.1E-4 T 29-03-2018 IPR012854 Copper amine oxidase-like, N-terminal CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 PRINTS PR00113 Alkaline phosphatase signature 263 292 3.8E-32 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 PRINTS PR00113 Alkaline phosphatase signature 186 196 3.8E-32 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 PRINTS PR00113 Alkaline phosphatase signature 44 64 3.8E-32 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 PRINTS PR00113 Alkaline phosphatase signature 142 162 3.8E-32 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS12680 5e014fe029e2060871558f1f49660cac 557 SMART SM00098 45 469 3.3E-82 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 SUPERFAMILY SSF56042 205 430 1.14E-56 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Gene3D G3DSA:3.30.1330.10 419 567 1.0E-52 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 739 330.973 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 SUPERFAMILY SSF55326 18 201 1.94E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 PIRSF PIRSF001587 8 739 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Gene3D G3DSA:3.30.1330.10 23 199 1.5E-56 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 737 0.0 T 29-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 3.4E-26 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 1.1E-25 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 710 2.8E-13 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 359 2.4E-34 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 SUPERFAMILY SSF55326 401 570 1.83E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 SUPERFAMILY SSF56042 571 738 5.83E-38 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Gene3D G3DSA:3.90.650.10 569 739 1.5E-35 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00050 21a8230b1e88586f641a147d61fa1ba7 739 Gene3D G3DSA:3.90.650.10 201 379 7.4E-29 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 Pfam PF00266 Aminotransferase class-V 200 469 1.8E-13 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 Gene3D G3DSA:3.40.630.30 3 173 4.8E-17 T 29-03-2018 CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 SUPERFAMILY SSF53383 180 520 2.3E-57 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 Gene3D G3DSA:3.40.640.10 190 415 7.5E-21 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 SUPERFAMILY SSF55729 5 164 2.93E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 Gene3D G3DSA:3.90.1150.10 416 519 8.2E-12 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS15725 9813486df2aa16d6292dea0f891f8760 527 Pfam PF13444 Acetyltransferase (GNAT) domain 20 112 6.4E-10 T 29-03-2018 CSW12_RS29430 635906a5678f1f7220fe78c1fd8776f5 467 Pfam PF13005 zinc-finger binding domain of transposase IS66 97 143 3.9E-9 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CSW12_RS29430 635906a5678f1f7220fe78c1fd8776f5 467 Pfam PF03050 Transposase IS66 family 159 428 2.0E-62 T 29-03-2018 IPR004291 Transposase, IS66 CSW12_RS29430 635906a5678f1f7220fe78c1fd8776f5 467 Gene3D G3DSA:1.10.1130.10 86 346 2.9E-4 T 29-03-2018 CSW12_RS10860 f8399ac218dd31530ec14da63d19dd80 167 SUPERFAMILY SSF52833 65 154 5.71E-6 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS10860 f8399ac218dd31530ec14da63d19dd80 167 Gene3D G3DSA:3.40.30.10 26 166 4.7E-7 T 29-03-2018 CSW12_RS24565 9867bddd1c9ff755f893e7329a26bbb2 163 SUPERFAMILY SSF101307 7 159 2.88E-58 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CSW12_RS24565 9867bddd1c9ff755f893e7329a26bbb2 163 PIRSF PIRSF019587 2 163 6.7E-78 T 29-03-2018 IPR026038 Putative phosphatidylglycerophosphatase CSW12_RS24565 9867bddd1c9ff755f893e7329a26bbb2 163 Pfam PF04608 Phosphatidylglycerophosphatase A 13 156 3.7E-21 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CSW12_RS24565 9867bddd1c9ff755f893e7329a26bbb2 163 Gene3D G3DSA:1.10.3760.10 1 163 3.7E-64 T 29-03-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CSW12_RS17670 d2e1ff64a5c78d5572bc64804e7d9b94 313 SUPERFAMILY SSF144083 249 310 2.62E-15 T 29-03-2018 CSW12_RS17670 d2e1ff64a5c78d5572bc64804e7d9b94 313 Pfam PF01544 CorA-like Mg2+ transporter protein 21 311 3.0E-65 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CSW12_RS17670 d2e1ff64a5c78d5572bc64804e7d9b94 313 Gene3D G3DSA:1.20.58.340 247 313 9.7E-16 T 29-03-2018 CSW12_RS17670 d2e1ff64a5c78d5572bc64804e7d9b94 313 Gene3D G3DSA:3.30.460.20 2 133 4.0E-23 T 29-03-2018 CSW12_RS17670 d2e1ff64a5c78d5572bc64804e7d9b94 313 SUPERFAMILY SSF143865 1 248 1.31E-56 T 29-03-2018 CSW12_RS17670 d2e1ff64a5c78d5572bc64804e7d9b94 313 Gene3D G3DSA:1.20.58.340 134 246 3.2E-13 T 29-03-2018 CSW12_RS15265 d6f47eafd55d47519c9ed468fdf56a0f 250 SMART SM00849 34 235 9.9E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS15265 d6f47eafd55d47519c9ed468fdf56a0f 250 Gene3D G3DSA:3.60.15.10 1 241 3.7E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS15265 d6f47eafd55d47519c9ed468fdf56a0f 250 SUPERFAMILY SSF56281 24 236 1.57E-38 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS15265 d6f47eafd55d47519c9ed468fdf56a0f 250 Pfam PF00753 Metallo-beta-lactamase superfamily 33 235 1.6E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 29-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 Pfam PF01479 S4 domain 93 139 7.4E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 SMART SM01390 3 91 6.9E-47 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 4.1E-84 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 Gene3D G3DSA:3.10.290.10 98 140 3.9E-18 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 SMART SM00363 92 156 8.6E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 Gene3D G3DSA:1.10.1050.10 1 97 4.3E-41 T 29-03-2018 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 35.903 T 29-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 1.3E-29 T 29-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 Gene3D G3DSA:1.10.1050.10 141 200 4.4E-14 T 29-03-2018 CSW12_RS22925 52395cdfd9a9de6baa918f7a97730bcd 200 SUPERFAMILY SSF55174 2 200 5.5E-68 T 29-03-2018 CSW12_RS26395 708b2e55c509056f126980a8493a4244 128 Pfam PF07681 DoxX 5 93 1.9E-19 T 29-03-2018 IPR032808 DoxX family CSW12_RS05100 eea220e0b31296ea6bc68736c54c52d2 795 SMART SM00885 334 483 9.7E-45 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CSW12_RS05100 eea220e0b31296ea6bc68736c54c52d2 795 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 434 740 6.4E-100 T 29-03-2018 IPR006500 DNA primase, phage/plasmid CSW12_RS05100 eea220e0b31296ea6bc68736c54c52d2 795 Pfam PF08706 D5 N terminal like 334 482 6.5E-30 T 29-03-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal CSW12_RS05100 eea220e0b31296ea6bc68736c54c52d2 795 Gene3D G3DSA:3.40.50.300 450 673 2.5E-14 T 29-03-2018 CSW12_RS05100 eea220e0b31296ea6bc68736c54c52d2 795 SUPERFAMILY SSF52540 514 667 8.5E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 Pfam PF07968 Leukocidin/Hemolysin toxin family 65 329 4.1E-85 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 TIGRFAM TIGR01002 hlyII: beta-channel forming cytolysin 11 332 2.8E-75 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 SUPERFAMILY SSF56959 32 335 1.05E-87 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 PRINTS PR01468 Staphylococcal bi-component toxin signature 68 87 3.4E-8 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 PRINTS PR01468 Staphylococcal bi-component toxin signature 135 156 3.4E-8 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 PRINTS PR01468 Staphylococcal bi-component toxin signature 261 278 3.4E-8 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS04800 7f164d5c1f9d181763f27091d7ffaa5a 336 Gene3D G3DSA:2.70.240.10 35 332 2.1E-86 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Gene3D G3DSA:3.40.50.920 493 630 3.3E-35 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Gene3D G3DSA:3.40.50.970 312 486 3.1E-43 T 29-03-2018 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 8.4E-295 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 278 7.1E-119 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52922 490 623 1.24E-32 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Pfam PF02780 Transketolase, C-terminal domain 493 615 3.3E-30 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52518 239 378 5.26E-74 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52518 5 193 5.26E-74 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 1.0E-38 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.885 T 29-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 SUPERFAMILY SSF52518 317 502 5.17E-53 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 SMART SM00861 316 481 1.6E-64 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS20470 c0b9194f73d3ade40d856ededfee26ca 630 Gene3D G3DSA:3.40.50.970 2 310 1.1E-77 T 29-03-2018 CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 SUPERFAMILY SSF51735 2 237 3.31E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 Gene3D G3DSA:3.40.50.720 1 38 0.0025 T 29-03-2018 CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 Gene3D G3DSA:3.40.50.720 39 241 1.4E-53 T 29-03-2018 CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 6.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 6.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 6.7E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 236 2.4E-55 T 29-03-2018 CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.6E-25 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS04635 977f158d08d85cfb867fe455e4beb942 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS08895 8a5c0e6736791985a368fa958b059b5a 264 Gene3D G3DSA:3.60.21.10 1 264 3.1E-50 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS08895 8a5c0e6736791985a368fa958b059b5a 264 Pfam PF13277 YmdB-like protein 4 254 4.8E-109 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CSW12_RS08895 8a5c0e6736791985a368fa958b059b5a 264 PIRSF PIRSF004789 1 263 1.7E-102 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CSW12_RS08895 8a5c0e6736791985a368fa958b059b5a 264 SUPERFAMILY SSF56300 1 256 2.34E-90 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS08895 8a5c0e6736791985a368fa958b059b5a 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 3.9E-114 T 29-03-2018 IPR005235 Metallophosphoesterase, YmdB-like CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Pfam PF13522 Glutamine amidotransferase domain 62 192 8.3E-19 T 29-03-2018 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 1.3E-225 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Gene3D G3DSA:3.40.50.10490 239 452 5.9E-57 T 29-03-2018 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 SUPERFAMILY SSF56235 2 234 6.26E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 SUPERFAMILY SSF53697 244 600 2.23E-93 T 29-03-2018 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Gene3D G3DSA:3.40.50.10490 453 598 2.5E-40 T 29-03-2018 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Gene3D G3DSA:3.60.20.10 2 238 2.5E-64 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Pfam PF01380 SIS domain 457 582 5.7E-17 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Pfam PF01380 SIS domain 287 413 6.6E-33 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CSW12_RS28290 724d4335ebae53bb6380960df2f20b94 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.416 T 29-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 511 9.5E-245 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 511 45.924 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 Pfam PF02142 MGS-like domain 14 129 6.8E-27 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 SMART SM00851 14 129 5.8E-56 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 PIRSF PIRSF000414 1 511 3.0E-216 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 SUPERFAMILY SSF52335 2 194 1.83E-69 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 Gene3D G3DSA:3.40.140.20 214 360 1.5E-57 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 Gene3D G3DSA:3.40.140.20 361 501 6.3E-51 T 29-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 444 2.7E-124 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 SUPERFAMILY SSF53927 206 511 6.72E-130 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 SMART SM00798 134 446 7.9E-203 T 29-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00070 a0e32c1df38e3ffcafe882dab0cebd66 511 Gene3D G3DSA:3.40.50.1380 1 192 3.4E-73 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 27 49 1.1E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 75 96 1.1E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 154 172 1.1E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 110 127 1.1E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 130 153 1.1E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 PRINTS PR00721 Stomatin signature 173 194 1.1E-28 T 29-03-2018 IPR001972 Stomatin family GO:0016020 CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 SMART SM00244 20 178 2.5E-58 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 Pfam PF01145 SPFH domain / Band 7 family 24 194 4.3E-34 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS17530 0242e7a9996cd620d0090201a7e5d25c 322 SUPERFAMILY SSF117892 51 185 3.53E-40 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS24580 bec66c911db89e1ac026a9429ad933de 448 SUPERFAMILY SSF53271 114 239 8.38E-8 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS24580 bec66c911db89e1ac026a9429ad933de 448 PIRSF PIRSF020967 114 441 9.4E-37 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CSW12_RS24580 bec66c911db89e1ac026a9429ad933de 448 PIRSF PIRSF020967 13 93 3.1E-12 T 29-03-2018 IPR011214 Uncharacterised conserved protein UCP020967 CSW12_RS24580 bec66c911db89e1ac026a9429ad933de 448 Pfam PF12500 TRSP domain C terminus to PRTase_2 302 428 7.4E-39 T 29-03-2018 IPR022537 TRSP domain CSW12_RS24580 bec66c911db89e1ac026a9429ad933de 448 Gene3D G3DSA:3.40.50.2020 28 271 1.0E-20 T 29-03-2018 CSW12_RS24580 bec66c911db89e1ac026a9429ad933de 448 Pfam PF15609 Phosphoribosyl transferase 42 257 1.0E-74 T 29-03-2018 CSW12_RS03855 1aa029ae7153dd0a9fa5cf2b58cbadf8 206 Gene3D G3DSA:3.40.30.10 6 205 6.2E-24 T 29-03-2018 CSW12_RS03855 1aa029ae7153dd0a9fa5cf2b58cbadf8 206 SUPERFAMILY SSF52833 8 205 2.41E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS03855 1aa029ae7153dd0a9fa5cf2b58cbadf8 206 Pfam PF01323 DSBA-like thioredoxin domain 11 182 8.9E-10 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CSW12_RS26140 c395f8f07b902b1c8e87deef2dc78ab9 293 Gene3D G3DSA:3.90.550.10 1 277 1.0E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS26140 c395f8f07b902b1c8e87deef2dc78ab9 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 1.7E-121 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CSW12_RS26140 c395f8f07b902b1c8e87deef2dc78ab9 293 SUPERFAMILY SSF53448 4 278 1.94E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS26140 c395f8f07b902b1c8e87deef2dc78ab9 293 Pfam PF00483 Nucleotidyl transferase 6 260 3.3E-35 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 SUPERFAMILY SSF158472 330 380 3.01E-9 T 29-03-2018 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 Gene3D G3DSA:3.30.565.10 456 616 7.4E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 Gene3D G3DSA:1.10.287.130 401 455 2.4E-14 T 29-03-2018 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 SUPERFAMILY SSF47384 382 461 3.53E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 Pfam PF00672 HAMP domain 330 377 2.6E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 SUPERFAMILY SSF55874 451 614 1.18E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 SMART SM00304 329 381 1.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 SMART SM00388 396 461 9.6E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 570 4.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 595 4.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 613 4.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 556 4.2E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 Pfam PF00512 His Kinase A (phospho-acceptor) domain 397 461 2.0E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 SMART SM00387 505 616 7.9E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 507 614 2.5E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23790 43d826de80deb32245371ba5af5db0ff 616 Gene3D G3DSA:3.30.450.20 367 400 0.0015 T 29-03-2018 CSW12_RS25425 bd0798b2491b7215efca49c670ff97f5 338 PIRSF PIRSF011570 1 335 1.4E-158 T 29-03-2018 IPR010894 Stage V sporulation AD CSW12_RS25425 bd0798b2491b7215efca49c670ff97f5 338 Gene3D G3DSA:3.40.47.10 24 334 3.6E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS25425 bd0798b2491b7215efca49c670ff97f5 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 2.9E-160 T 29-03-2018 IPR010894 Stage V sporulation AD CSW12_RS25425 bd0798b2491b7215efca49c670ff97f5 338 SUPERFAMILY SSF53901 56 308 4.8E-16 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS25425 bd0798b2491b7215efca49c670ff97f5 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 2.9E-156 T 29-03-2018 IPR010894 Stage V sporulation AD CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 Pfam PF07883 Cupin domain 102 169 8.8E-13 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 Pfam PF12844 Helix-turn-helix domain 4 62 3.3E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 SUPERFAMILY SSF47413 1 66 2.76E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 Gene3D G3DSA:2.60.120.10 79 180 2.4E-13 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 SUPERFAMILY SSF51182 54 171 7.36E-22 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 Gene3D G3DSA:1.10.260.40 1 78 9.0E-18 T 29-03-2018 CSW12_RS21435 018c5dcf7ea63f4dc13388332ba19e9b 181 SMART SM00530 6 61 5.0E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS28405 f7095524e6b919d4ab94a0ab4b3deff0 155 Gene3D G3DSA:3.40.190.10 1 152 1.6E-4 T 29-03-2018 CSW12_RS28405 f7095524e6b919d4ab94a0ab4b3deff0 155 Pfam PF14039 YusW-like protein 51 144 1.4E-25 T 29-03-2018 IPR025623 YusW-like protein CSW12_RS05825 7a7e11fa595b55e4947b180385a6e278 649 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 266 604 8.0E-89 T 29-03-2018 IPR003776 YcaO-like domain CSW12_RS05825 7a7e11fa595b55e4947b180385a6e278 649 Gene3D G3DSA:3.40.50.720 15 190 9.9E-9 T 29-03-2018 CSW12_RS05825 7a7e11fa595b55e4947b180385a6e278 649 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 266 649 4.7E-143 T 29-03-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component CSW12_RS05825 7a7e11fa595b55e4947b180385a6e278 649 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 68 237 3.8E-43 T 29-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CSW12_RS05825 7a7e11fa595b55e4947b180385a6e278 649 SUPERFAMILY SSF69572 54 223 1.67E-7 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 Gene3D G3DSA:3.90.110.10 147 313 3.5E-52 T 29-03-2018 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 9.3E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 9.3E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 9.3E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 9.3E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 9.3E-50 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 SUPERFAMILY SSF56327 146 312 1.21E-59 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 1.5E-135 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 SUPERFAMILY SSF51735 4 145 2.26E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 8.7E-48 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 Gene3D G3DSA:3.40.50.720 7 146 5.3E-39 T 29-03-2018 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 48.328 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 PIRSF PIRSF000102 2 313 1.7E-116 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24115 c615f5404abf4f3dc702b312436f5de3 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 5.3E-39 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CSW12_RS30475 792b3fc5adbab4fedfe6806ed6ecdf52 395 Pfam PF01548 Transposase 4 162 1.4E-41 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS30475 792b3fc5adbab4fedfe6806ed6ecdf52 395 Pfam PF02371 Transposase IS116/IS110/IS902 family 270 354 7.0E-26 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS29710 792b3fc5adbab4fedfe6806ed6ecdf52 395 Pfam PF01548 Transposase 4 162 1.4E-41 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS29710 792b3fc5adbab4fedfe6806ed6ecdf52 395 Pfam PF02371 Transposase IS116/IS110/IS902 family 270 354 7.0E-26 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS09165 86e5690743e8920f92c2ec66af169a38 360 Gene3D G3DSA:3.20.20.80 28 360 8.4E-56 T 29-03-2018 CSW12_RS09165 86e5690743e8920f92c2ec66af169a38 360 SMART SM00636 34 338 1.6E-7 T 29-03-2018 IPR011583 Chitinase II GO:0008061 CSW12_RS09165 86e5690743e8920f92c2ec66af169a38 360 SUPERFAMILY SSF51445 33 347 6.28E-60 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS09165 86e5690743e8920f92c2ec66af169a38 360 ProSitePatterns PS01095 Chitinases family 18 active site. 137 145 - T 29-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CSW12_RS09165 86e5690743e8920f92c2ec66af169a38 360 Pfam PF00704 Glycosyl hydrolases family 18 36 338 1.9E-29 T 29-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 325 1.5E-30 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 305 7.1E-20 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 Pfam PF00005 ABC transporter 37 187 1.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 SMART SM00382 45 237 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 SUPERFAMILY SSF52540 9 259 1.03E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03850 716b3b0fa6ca090e5de64082f7a7ea75 326 Gene3D G3DSA:3.40.50.300 6 326 2.3E-89 T 29-03-2018 CSW12_RS29305 24e1fcde9a351bc9b2692f655d1fda39 314 SUPERFAMILY SSF56349 1 308 9.71E-20 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS29305 24e1fcde9a351bc9b2692f655d1fda39 314 Pfam PF00589 Phage integrase family 143 302 6.3E-10 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS29305 24e1fcde9a351bc9b2692f655d1fda39 314 Gene3D G3DSA:1.10.443.10 109 313 2.3E-15 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS29305 24e1fcde9a351bc9b2692f655d1fda39 314 Gene3D G3DSA:1.10.150.130 1 108 4.9E-13 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 SUPERFAMILY SSF52821 369 473 1.7E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 Gene3D G3DSA:3.60.15.10 1 266 1.3E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 Pfam PF00581 Rhodanese-like domain 385 466 4.2E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 Gene3D G3DSA:3.40.250.10 362 473 1.8E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 Gene3D G3DSA:3.40.250.10 277 354 1.7E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 SUPERFAMILY SSF52821 239 354 2.1E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 SMART SM00849 12 199 1.1E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 SMART SM00450 272 367 12.0 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 SMART SM00450 375 470 1.3E-23 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 Pfam PF00753 Metallo-beta-lactamase superfamily 13 189 8.3E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS30035 9c10cc55656a0ed141571c3efdf590de 473 SUPERFAMILY SSF56281 12 261 7.56E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 SMART SM00228 111 182 9.9E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF47090 384 454 1.02E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:3.90.226.10 192 388 5.9E-58 T 29-03-2018 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Pfam PF13180 PDZ domain 112 184 2.0E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF50156 82 204 1.97E-21 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:3.30.750.44 34 110 2.2E-17 T 29-03-2018 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:1.10.101.10 389 457 2.5E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Gene3D G3DSA:2.30.42.10 111 191 8.0E-18 T 29-03-2018 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 64 380 3.2E-120 T 29-03-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Pfam PF03572 Peptidase family S41 212 374 8.6E-51 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 Pfam PF01471 Putative peptidoglycan binding domain 399 452 2.4E-15 T 29-03-2018 IPR002477 Peptidoglycan binding-like CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF52096 206 379 1.7E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 SUPERFAMILY SSF52096 48 129 1.7E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS25605 064dcec36aaf3ef0f04411e5306bc44f 478 SMART SM00245 184 375 1.7E-65 T 29-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 37 56 4.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 267 288 4.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 126 148 4.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 PRINTS PR01035 Tetracycline resistance protein signature 239 259 4.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 SUPERFAMILY SSF103473 4 377 6.93E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS02330 64114f40c002c0134c34849116c63493 384 Gene3D G3DSA:1.20.1250.20 3 190 2.3E-32 T 29-03-2018 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 Pfam PF03209 PUCC protein 270 352 4.3E-6 T 29-03-2018 IPR004896 PucC-related CSW12_RS02330 64114f40c002c0134c34849116c63493 384 Gene3D G3DSA:1.20.1250.20 191 382 1.1E-25 T 29-03-2018 CSW12_RS02330 64114f40c002c0134c34849116c63493 384 Pfam PF07690 Major Facilitator Superfamily 6 227 1.2E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 Pfam PF14841 FliG middle domain 118 186 1.6E-18 T 29-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 Gene3D G3DSA:1.10.220.30 70 189 3.0E-11 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 Gene3D G3DSA:1.10.220.30 195 334 3.5E-23 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 SUPERFAMILY SSF48029 115 326 3.27E-49 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 2 333 1.6E-68 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 Pfam PF01706 FliG C-terminal domain 218 324 8.0E-31 T 29-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 5 21 5.9E-40 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 114 137 5.9E-40 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 195 220 5.9E-40 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 226 246 5.9E-40 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 273 299 5.9E-40 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 PRINTS PR00954 Flagellar motor switch protein FliG signature 34 60 5.9E-40 T 29-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 Gene3D G3DSA:1.10.220.30 2 69 2.1E-8 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 Pfam PF14842 FliG N-terminal domain 5 101 1.9E-16 T 29-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CSW12_RS19340 25c7134231c694afcd748a35946d143f 334 SUPERFAMILY SSF48029 8 112 4.84E-15 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS08560 55a3ea6a781956a5b176c020de2a6f73 75 Hamap MF_00088 UPF0109 protein . 1 75 21.45 T 29-03-2018 IPR020627 Uncharacterised protein family UPF0109 CSW12_RS08560 55a3ea6a781956a5b176c020de2a6f73 75 Gene3D G3DSA:3.30.300.20 1 75 1.4E-16 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS08560 55a3ea6a781956a5b176c020de2a6f73 75 SUPERFAMILY SSF54814 15 58 1.96E-7 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CSW12_RS08560 55a3ea6a781956a5b176c020de2a6f73 75 Pfam PF13083 KH domain 2 74 7.6E-23 T 29-03-2018 CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 Gene3D G3DSA:3.90.100.10 378 472 3.5E-22 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 Gene3D G3DSA:3.40.640.10 6 277 2.0E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 397 453 3.0E-13 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 Gene3D G3DSA:3.90.1150.10 278 377 3.4E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 SUPERFAMILY SSF55904 331 464 8.37E-28 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 SUPERFAMILY SSF53383 7 361 1.61E-83 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS27490 8ad50e00e56042714baeaf05569def52 473 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 305 1.6E-76 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CSW12_RS14985 253bcb4d3e149161c9e444db1cf7d169 186 SUPERFAMILY SSF52540 4 163 2.08E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14985 253bcb4d3e149161c9e444db1cf7d169 186 Gene3D G3DSA:3.40.50.300 1 74 2.4E-5 T 29-03-2018 CSW12_RS14985 253bcb4d3e149161c9e444db1cf7d169 186 Gene3D G3DSA:3.40.50.300 75 183 9.0E-15 T 29-03-2018 CSW12_RS14985 253bcb4d3e149161c9e444db1cf7d169 186 Pfam PF13238 AAA domain 8 129 2.6E-7 T 29-03-2018 CSW12_RS19380 3a2e86eab87000e94a5c06a2e0d938a9 287 Gene3D G3DSA:1.20.1330.10 39 262 1.0E-28 T 29-03-2018 CSW12_RS19380 3a2e86eab87000e94a5c06a2e0d938a9 287 Pfam PF00700 Bacterial flagellin C-terminal helical region 211 287 5.9E-6 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19380 3a2e86eab87000e94a5c06a2e0d938a9 287 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 163 9.0E-49 T 29-03-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CSW12_RS19380 3a2e86eab87000e94a5c06a2e0d938a9 287 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 1.2E-10 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19380 3a2e86eab87000e94a5c06a2e0d938a9 287 SUPERFAMILY SSF64518 1 287 2.35E-47 T 29-03-2018 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 SUPERFAMILY SSF56024 95 338 4.71E-51 T 29-03-2018 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 36 509 6.7E-148 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Gene3D G3DSA:3.30.870.10 115 304 5.9E-35 T 29-03-2018 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Hamap MF_01916 Cardiolipin synthase. 34 509 39.52 T 29-03-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Gene3D G3DSA:1.20.1560.10 24 109 1.0E-4 T 29-03-2018 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Pfam PF13091 PLD-like domain 155 298 7.8E-15 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Pfam PF13091 PLD-like domain 351 476 6.5E-26 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Gene3D G3DSA:3.30.870.10 331 500 1.1E-29 T 29-03-2018 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 SMART SM00155 422 449 3.6E-7 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 SMART SM00155 238 265 5.7E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 SUPERFAMILY SSF56024 290 493 8.52E-44 T 29-03-2018 CSW12_RS01835 1181d42b5876b72895053af4dd7db2d3 509 Pfam PF13396 Phospholipase_D-nuclease N-terminal 39 81 1.4E-9 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CSW12_RS28645 5e58d52d2c35efa86e174aeff5256ad1 390 SUPERFAMILY SSF51182 5 382 6.41E-100 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS28645 5e58d52d2c35efa86e174aeff5256ad1 390 Gene3D G3DSA:2.60.120.10 215 360 1.1E-31 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS28645 5e58d52d2c35efa86e174aeff5256ad1 390 Pfam PF04209 homogentisate 1,2-dioxygenase 103 382 2.7E-19 T 29-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CSW12_RS28645 5e58d52d2c35efa86e174aeff5256ad1 390 Gene3D G3DSA:2.60.120.10 51 195 1.1E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS23065 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Gene3D G3DSA:3.10.570.10 37 117 3.4E-15 T 29-03-2018 CSW12_RS23065 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Gene3D G3DSA:3.10.570.10 118 340 2.4E-56 T 29-03-2018 CSW12_RS23065 afb4cc2f53e1ede1f0cec69e8fc3470a 340 PIRSF PIRSF012509 1 340 6.0E-94 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CSW12_RS23065 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Pfam PF07537 CamS sex pheromone cAM373 precursor 120 333 9.0E-47 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CSW12_RS23065 afb4cc2f53e1ede1f0cec69e8fc3470a 340 Pfam PF07537 CamS sex pheromone cAM373 precursor 70 116 7.6E-6 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CSW12_RS18405 fdaec8459368d7cfa38ca5a29e03e3b6 194 Gene3D G3DSA:1.10.260.40 44 138 2.0E-6 T 29-03-2018 CSW12_RS18405 fdaec8459368d7cfa38ca5a29e03e3b6 194 SUPERFAMILY SSF46689 13 72 3.99E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS18405 fdaec8459368d7cfa38ca5a29e03e3b6 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 8.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS18405 fdaec8459368d7cfa38ca5a29e03e3b6 194 Gene3D G3DSA:1.10.10.60 6 43 2.3E-7 T 29-03-2018 CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 SUPERFAMILY SSF48019 214 333 1.53E-26 T 29-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 Gene3D G3DSA:1.10.8.60 144 222 9.1E-20 T 29-03-2018 CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 333 6.9E-101 T 29-03-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 Gene3D G3DSA:1.20.272.10 223 336 1.1E-36 T 29-03-2018 CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 Gene3D G3DSA:3.40.50.300 1 141 8.2E-29 T 29-03-2018 CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 SUPERFAMILY SSF52540 9 210 2.12E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21235 0064058b7eb7cf4729b735db45199a6b 336 Pfam PF06144 DNA polymerase III, delta subunit 17 191 2.2E-47 T 29-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CSW12_RS26165 dafe5b8114f7d0b693b329bd512f49be 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 139 9.2E-58 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS26165 dafe5b8114f7d0b693b329bd512f49be 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.67 T 29-03-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS26165 dafe5b8114f7d0b693b329bd512f49be 144 SUPERFAMILY SSF54637 1 139 6.71E-48 T 29-03-2018 IPR029069 HotDog domain CSW12_RS26165 dafe5b8114f7d0b693b329bd512f49be 144 Pfam PF07977 FabA-like domain 11 134 7.2E-35 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS26165 dafe5b8114f7d0b693b329bd512f49be 144 Gene3D G3DSA:3.10.129.10 1 144 1.1E-55 T 29-03-2018 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 192 349 4.0E-38 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF52156 469 597 8.63E-39 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:3.40.50.300 185 358 1.3E-41 T 29-03-2018 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF50447 591 688 1.85E-33 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 688 17.515 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF11987 Translation-initiation factor 2 475 580 1.5E-37 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF52540 178 362 1.7E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:3.30.56.50 115 156 3.0E-11 T 29-03-2018 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:3.30.56.50 4 46 1.1E-12 T 29-03-2018 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:2.40.30.10 359 455 7.9E-14 T 29-03-2018 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:3.40.50.10050 488 569 1.3E-27 T 29-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 SUPERFAMILY SSF50447 362 444 5.82E-25 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 ProSitePatterns PS01176 Initiation factor 2 signature. 641 663 - T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 106 688 5.1E-278 T 29-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Gene3D G3DSA:2.40.30.10 591 688 7.8E-31 T 29-03-2018 CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 51 2.0E-14 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 115 163 5.9E-16 T 29-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CSW12_RS08715 ca5d3ebb957af41168b4e945c8f499a2 688 Pfam PF00009 Elongation factor Tu GTP binding domain 195 350 3.3E-37 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS05745 2dec209c84569d5b1d5f658b14b8fddf 258 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 29-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS05745 2dec209c84569d5b1d5f658b14b8fddf 258 Gene3D G3DSA:3.20.20.70 3 257 1.6E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS05745 2dec209c84569d5b1d5f658b14b8fddf 258 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 11 248 8.8E-77 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS05745 2dec209c84569d5b1d5f658b14b8fddf 258 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 11 255 33.419 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS05745 2dec209c84569d5b1d5f658b14b8fddf 258 SUPERFAMILY SSF51366 6 252 1.88E-83 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS05745 2dec209c84569d5b1d5f658b14b8fddf 258 Pfam PF00290 Tryptophan synthase alpha chain 10 255 1.6E-88 T 29-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS19165 84d27ce5a4c9805dd913082a5f65df96 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 30 83 3.1E-7 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CSW12_RS19165 84d27ce5a4c9805dd913082a5f65df96 111 Gene3D G3DSA:3.30.70.100 9 101 4.0E-23 T 29-03-2018 CSW12_RS19165 84d27ce5a4c9805dd913082a5f65df96 111 SUPERFAMILY SSF54909 8 106 1.4E-29 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 SUPERFAMILY SSF143548 19 137 3.01E-32 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 PIRSF PIRSF036692 1 219 2.6E-107 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 Gene3D G3DSA:3.30.1330.90 20 141 6.4E-30 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 Pfam PF01842 ACT domain 149 208 8.6E-11 T 29-03-2018 IPR002912 ACT domain CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 206 1.1E-81 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 Pfam PF03315 Serine dehydratase beta chain 5 81 2.0E-14 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 Gene3D G3DSA:3.30.70.260 142 218 8.3E-16 T 29-03-2018 CSW12_RS20240 28a5e0d19565e7eebfd99072d610f23d 219 SUPERFAMILY SSF55021 136 217 4.2E-16 T 29-03-2018 CSW12_RS18255 e89034e9c11a97a1ebba097d80923550 216 SUPERFAMILY SSF52833 1 200 3.8E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS18255 e89034e9c11a97a1ebba097d80923550 216 Pfam PF01323 DSBA-like thioredoxin domain 6 193 4.1E-30 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CSW12_RS18255 e89034e9c11a97a1ebba097d80923550 216 ProSitePatterns PS00195 Glutaredoxin active site. 7 23 - T 29-03-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CSW12_RS18255 e89034e9c11a97a1ebba097d80923550 216 Gene3D G3DSA:3.40.30.10 1 197 8.9E-41 T 29-03-2018 CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 SUPERFAMILY SSF51556 59 358 1.12E-94 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 Gene3D G3DSA:2.30.40.10 1 71 2.2E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 SUPERFAMILY SSF51338 4 59 3.05E-32 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 SUPERFAMILY SSF51338 358 433 3.05E-32 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 Gene3D G3DSA:3.20.20.140 72 375 3.2E-63 T 29-03-2018 CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 434 44.063 T 29-03-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 CSW12_RS18535 b9fdde9b6ce4d196f9bb006e4ee894de 435 Pfam PF01979 Amidohydrolase family 56 408 5.6E-74 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 SUPERFAMILY SSF46785 7 57 4.23E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 Gene3D G3DSA:3.10.129.10 42 190 3.4E-24 T 29-03-2018 CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 SUPERFAMILY SSF54637 76 185 4.16E-26 T 29-03-2018 IPR029069 HotDog domain CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 Hamap MF_01814 Transcription factor FapR [fapR]. 3 190 41.082 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 Gene3D G3DSA:1.10.10.10 1 41 5.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 PIRSF PIRSF037733 1 193 1.1E-84 T 29-03-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 CSW12_RS08505 a2bec94e433f86c76476ed25bcf4f57d 197 Pfam PF03061 Thioesterase superfamily 113 171 3.2E-6 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS19435 323f49c92674ac3b2ccfc3025911cb73 225 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 5 50 4.4E-13 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CSW12_RS19435 323f49c92674ac3b2ccfc3025911cb73 225 Gene3D G3DSA:3.30.1330.60 53 225 2.0E-35 T 29-03-2018 IPR006665 OmpA-like domain CSW12_RS19435 323f49c92674ac3b2ccfc3025911cb73 225 SUPERFAMILY SSF103088 107 223 5.49E-31 T 29-03-2018 IPR006665 OmpA-like domain CSW12_RS19435 323f49c92674ac3b2ccfc3025911cb73 225 Pfam PF00691 OmpA family 119 217 1.1E-17 T 29-03-2018 IPR006665 OmpA-like domain CSW12_RS03810 568af6a6abc541a42e895de578e66855 76 Pfam PF11121 Protein of unknown function (DUF2639) 30 66 2.4E-20 T 29-03-2018 IPR022580 Protein of unknown function DUF2639 CSW12_RS03810 568af6a6abc541a42e895de578e66855 76 ProDom PD049467 YFLJ 29 66 1.0E-15 T 29-03-2018 IPR022580 Protein of unknown function DUF2639 CSW12_RS00425 35fb31b804804e9ae5f164082cf9498b 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 98.156 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS00425 35fb31b804804e9ae5f164082cf9498b 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.1E-203 T 29-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS00425 35fb31b804804e9ae5f164082cf9498b 485 ProSitePatterns PS00571 Amidases signature. 151 182 - T 29-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CSW12_RS00425 35fb31b804804e9ae5f164082cf9498b 485 Pfam PF01425 Amidase 24 465 2.3E-162 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS00425 35fb31b804804e9ae5f164082cf9498b 485 SUPERFAMILY SSF75304 1 480 2.22E-167 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS00425 35fb31b804804e9ae5f164082cf9498b 485 Gene3D G3DSA:3.90.1300.10 1 485 5.3E-173 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 SUPERFAMILY SSF88659 182 253 4.11E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 Pfam PF04539 Sigma-70 region 3 117 188 5.2E-15 T 29-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 SUPERFAMILY SSF88946 11 104 3.14E-27 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 Gene3D G3DSA:1.10.601.10 1 103 6.1E-21 T 29-03-2018 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 Pfam PF04542 Sigma-70 region 2 35 104 1.4E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 29 253 3.5E-86 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 2 255 3.0E-142 T 29-03-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 253 1.7E-32 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 SUPERFAMILY SSF88659 108 179 2.62E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 Gene3D G3DSA:1.10.10.10 183 254 4.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 PRINTS PR00046 Major sigma-70 factor signature 224 239 3.3E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 PRINTS PR00046 Major sigma-70 factor signature 59 72 3.3E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 PRINTS PR00046 Major sigma-70 factor signature 207 219 3.3E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 PRINTS PR00046 Major sigma-70 factor signature 239 250 3.3E-7 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 Gene3D G3DSA:1.10.10.10 105 157 1.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 Pfam PF04545 Sigma-70, region 4 205 252 3.0E-14 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04295 6560ddc578df7176bef1cc17b2fc8d5b 258 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 59 72 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS05140 26c700d7c8e1cddbd1bbb122bd965519 121 Pfam PF01844 HNH endonuclease 59 100 1.5E-9 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CSW12_RS05140 26c700d7c8e1cddbd1bbb122bd965519 121 Gene3D G3DSA:3.40.1800.10 37 118 1.0E-12 T 29-03-2018 CSW12_RS05140 26c700d7c8e1cddbd1bbb122bd965519 121 SMART SM00507 46 101 7.6E-6 T 29-03-2018 IPR003615 HNH nuclease CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 PIRSF PIRSF000183 1 371 2.2E-193 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 SMART SM01003 4 136 8.4E-79 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.7E-47 T 29-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 4.6E-182 T 29-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 29-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 Gene3D G3DSA:3.40.50.720 186 371 5.7E-46 T 29-03-2018 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 Gene3D G3DSA:3.40.50.720 1 185 3.3E-44 T 29-03-2018 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 4.9E-83 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 SMART SM01002 148 297 6.6E-90 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 SUPERFAMILY SSF52283 305 360 1.45E-68 T 29-03-2018 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 SUPERFAMILY SSF52283 1 136 1.45E-68 T 29-03-2018 CSW12_RS22740 11edd7f9876d2f889b7e90f7beebfc04 377 SUPERFAMILY SSF51735 136 303 3.19E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS12775 ffe65f448031270c563ec7fcaed42a68 139 SUPERFAMILY SSF54593 1 124 1.11E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12775 ffe65f448031270c563ec7fcaed42a68 139 Gene3D G3DSA:3.10.180.10 1 139 2.7E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12775 ffe65f448031270c563ec7fcaed42a68 139 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 119 9.3E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 ProSitePatterns PS00885 EPSP synthase signature 2. 341 359 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Gene3D G3DSA:3.65.10.10 22 222 1.8E-52 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 12 424 3.6E-128 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 SUPERFAMILY SSF55205 11 427 1.64E-137 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Gene3D G3DSA:3.65.10.10 223 429 5.1E-56 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 428 1.3E-134 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 PIRSF PIRSF000505 1 429 1.8E-119 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 29-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CSW12_RS12925 e31cdd1a5884c87dd2c35b93c06c7a7a 429 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 429 33.641 T 29-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 SUPERFAMILY SSF100879 260 357 7.65E-10 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 SUPERFAMILY SSF56672 10 249 8.54E-51 T 29-03-2018 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Pfam PF00817 impB/mucB/samB family 15 165 6.0E-27 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Gene3D G3DSA:1.10.150.20 186 262 2.1E-17 T 29-03-2018 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Gene3D G3DSA:3.30.70.270 128 185 1.1E-6 T 29-03-2018 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Gene3D G3DSA:3.30.70.270 51 127 1.1E-11 T 29-03-2018 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 254 364 8.1E-13 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Pfam PF11798 IMS family HHH motif 181 213 8.6E-7 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CSW12_RS12175 ccc3b9c81b63d94b0653700f399e6dd5 421 Gene3D G3DSA:3.30.1490.100 263 371 6.6E-18 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS23210 5a5ff035210b73ca8a5bc1968ae86d6c 73 SMART SM00420 11 56 8.0E-4 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS23210 5a5ff035210b73ca8a5bc1968ae86d6c 73 Gene3D G3DSA:1.10.10.10 1 70 2.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23210 5a5ff035210b73ca8a5bc1968ae86d6c 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 50 8.6E-11 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS23210 5a5ff035210b73ca8a5bc1968ae86d6c 73 SUPERFAMILY SSF46785 10 58 5.17E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21155 7ce1cc738a9e071bbc2669590770ab00 147 Gene3D G3DSA:1.10.10.410 91 147 9.8E-19 T 29-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CSW12_RS21155 7ce1cc738a9e071bbc2669590770ab00 147 SUPERFAMILY SSF89095 1 146 1.83E-42 T 29-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CSW12_RS21155 7ce1cc738a9e071bbc2669590770ab00 147 Pfam PF09424 Yqey-like protein 6 146 1.5E-53 T 29-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CSW12_RS21155 7ce1cc738a9e071bbc2669590770ab00 147 Gene3D G3DSA:1.10.1510.10 1 90 2.4E-27 T 29-03-2018 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 SUPERFAMILY SSF53738 306 457 6.28E-32 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Gene3D G3DSA:3.40.120.10 14 213 3.6E-56 T 29-03-2018 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Gene3D G3DSA:3.40.120.10 339 457 4.3E-37 T 29-03-2018 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Gene3D G3DSA:3.30.310.50 469 574 7.6E-26 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 298 313 2.7E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 2.7E-5 T 29-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 29-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 SUPERFAMILY SSF55957 470 556 3.27E-15 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 SUPERFAMILY SSF53738 29 238 9.03E-47 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 SUPERFAMILY SSF53738 209 319 1.73E-19 T 29-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Gene3D G3DSA:3.40.120.10 214 338 1.1E-30 T 29-03-2018 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 317 2.9E-22 T 29-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 495 556 2.6E-11 T 29-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 180 9.3E-41 T 29-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS24385 01352a67f9e6b1192c4be30ecb0bde60 574 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 453 1.6E-22 T 29-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 Pfam PF00239 Resolvase, N terminal domain 4 140 1.2E-36 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 Gene3D G3DSA:1.20.5.40 109 129 1.9E-11 T 29-03-2018 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 Gene3D G3DSA:1.10.10.60 130 188 3.5E-8 T 29-03-2018 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 SMART SM00857 3 140 5.4E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 Gene3D G3DSA:3.40.50.1390 1 108 2.3E-27 T 29-03-2018 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 SUPERFAMILY SSF53041 1 140 3.66E-37 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS02575 47a5381d996d17aeee568745c1061aab 204 Pfam PF02796 Helix-turn-helix domain of resolvase 142 187 2.3E-7 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 SUPERFAMILY SSF46689 4 69 5.13E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 Gene3D G3DSA:1.10.10.60 5 39 4.7E-15 T 29-03-2018 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 Gene3D G3DSA:1.10.260.40 40 178 1.9E-9 T 29-03-2018 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.4E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 3.8E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04605 0a5cce1ba37f0f89254788c1166863f4 178 SUPERFAMILY SSF48498 102 173 1.31E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 SUPERFAMILY SSF54373 226 310 1.05E-18 T 29-03-2018 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 Gene3D G3DSA:3.30.9.10 168 310 1.0E-30 T 29-03-2018 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 SUPERFAMILY SSF51905 4 225 2.78E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 SUPERFAMILY SSF51905 312 368 2.78E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 356 1.7E-131 T 29-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 Gene3D G3DSA:3.50.50.60 3 88 1.3E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 Gene3D G3DSA:3.30.9.10 92 167 5.0E-4 T 29-03-2018 CSW12_RS02975 67b151768a7df6b06c19e7d915935d75 369 Pfam PF01266 FAD dependent oxidoreductase 6 351 4.7E-75 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS00255 c9147269c64f59c65f943dfdebd4df5e 251 Pfam PF13688 Metallo-peptidase family M12 81 227 4.3E-22 T 29-03-2018 CSW12_RS00255 c9147269c64f59c65f943dfdebd4df5e 251 Gene3D G3DSA:3.40.390.10 61 242 1.8E-12 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CSW12_RS00255 c9147269c64f59c65f943dfdebd4df5e 251 SUPERFAMILY SSF55486 80 233 9.87E-15 T 29-03-2018 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 5 336 66.177 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 7 318 4.4E-137 T 29-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 SUPERFAMILY SSF53067 6 126 3.3E-33 T 29-03-2018 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 Gene3D G3DSA:3.30.420.40 149 293 2.2E-20 T 29-03-2018 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 SUPERFAMILY SSF53067 105 313 1.3E-46 T 29-03-2018 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 29-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 2.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 2.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 134 146 2.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 8 21 2.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 2.4E-50 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 8 311 1.3E-112 T 29-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 Gene3D G3DSA:3.30.420.40 5 148 3.5E-46 T 29-03-2018 CSW12_RS28825 f91e3ded8141a300168e97cec5e81202 338 Pfam PF00814 Glycoprotease family 27 311 4.4E-109 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PIRSF PIRSF038928 384 459 1.6E-9 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PIRSF PIRSF038928 7 390 8.7E-151 T 29-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 ProSitePatterns PS00438 Catalase proximal active site signature. 54 70 - T 29-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 Gene3D G3DSA:2.40.180.10 2 367 1.2E-124 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 SUPERFAMILY SSF56634 28 456 5.1E-152 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 SMART SM01060 18 393 1.1E-176 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 Pfam PF00199 Catalase 27 384 2.1E-131 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 Pfam PF06628 Catalase-related immune-responsive 395 454 3.9E-14 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PRINTS PR00067 Catalase signature 94 112 1.9E-51 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PRINTS PR00067 Catalase signature 134 152 1.9E-51 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PRINTS PR00067 Catalase signature 331 357 1.9E-51 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PRINTS PR00067 Catalase signature 31 54 1.9E-51 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PRINTS PR00067 Catalase signature 299 326 1.9E-51 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS12590 d3ef385b3e9c1477fdb561b8ddb341b2 459 PRINTS PR00067 Catalase signature 115 132 1.9E-51 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 SUPERFAMILY SSF52540 334 558 1.28E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Pfam PF00005 ABC transporter 37 213 3.9E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Pfam PF00005 ABC transporter 365 494 6.8E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Pfam PF16326 ABC transporter C-terminal domain 595 660 2.0E-14 T 29-03-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Gene3D G3DSA:1.20.58.410 593 662 2.1E-7 T 29-03-2018 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 SMART SM00382 46 258 2.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 SMART SM00382 373 539 5.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Gene3D G3DSA:3.40.50.300 6 294 1.8E-53 T 29-03-2018 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Gene3D G3DSA:3.40.50.300 310 576 8.3E-52 T 29-03-2018 CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 Pfam PF12848 ABC transporter 252 338 1.7E-24 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 SUPERFAMILY SSF52540 22 266 1.18E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28830 9ceaef80b909819017b461bacf962445 662 ProSitePatterns PS00211 ABC transporters family signature. 185 199 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 3.1E-14 T 29-03-2018 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 SMART SM00344 7 111 1.4E-30 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 5.2E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 5.2E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 5.2E-12 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 Gene3D G3DSA:3.30.70.920 60 128 2.6E-12 T 29-03-2018 CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 Pfam PF01037 Lrp/AsnC ligand binding domain 78 126 1.5E-10 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 Gene3D G3DSA:1.10.10.10 1 58 2.0E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 SUPERFAMILY SSF46785 6 65 1.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11950 6654724312c53f9a27ae7a8cd24128be 146 SUPERFAMILY SSF54909 71 139 4.02E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS02430 fd219e2d89feaba0982558cfcd367745 156 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 9 144 1.3E-50 T 29-03-2018 IPR006524 Transcription activator, ArpU family CSW12_RS02430 fd219e2d89feaba0982558cfcd367745 156 Gene3D G3DSA:1.10.10.10 53 144 4.8E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02430 fd219e2d89feaba0982558cfcd367745 156 SUPERFAMILY SSF88659 75 106 7.66E-5 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS07495 8a64468a63a6049824875cbfc5e5b1d8 212 SUPERFAMILY SSF53639 5 201 2.75E-44 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS07495 8a64468a63a6049824875cbfc5e5b1d8 212 SMART SM01007 9 195 2.7E-39 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS07495 8a64468a63a6049824875cbfc5e5b1d8 212 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 11 199 4.6E-63 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CSW12_RS07495 8a64468a63a6049824875cbfc5e5b1d8 212 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 203 101.17 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CSW12_RS07495 8a64468a63a6049824875cbfc5e5b1d8 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 193 4.3E-39 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS07495 8a64468a63a6049824875cbfc5e5b1d8 212 Gene3D G3DSA:3.40.225.10 5 210 3.5E-43 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 SMART SM00644 13 154 2.7E-28 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 Gene3D G3DSA:3.40.80.10 1 159 2.1E-38 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 22 139 9.9E-17 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 Pfam PF08239 Bacterial SH3 domain 261 308 3.6E-6 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 Gene3D G3DSA:2.40.50.110 168 231 7.2E-9 T 29-03-2018 CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 SMART SM00287 177 231 0.49 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 SMART SM00287 252 311 0.0018 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 Gene3D G3DSA:2.30.30.410 235 311 1.8E-11 T 29-03-2018 CSW12_RS02255 76b4cca78fa910b85688485708257f20 311 SUPERFAMILY SSF55846 4 155 2.09E-51 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 Pfam PF02780 Transketolase, C-terminal domain 549 658 8.9E-14 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 Gene3D G3DSA:3.40.50.970 1 361 1.3E-113 T 29-03-2018 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 2.5E-158 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 Gene3D G3DSA:3.40.50.970 362 543 4.1E-44 T 29-03-2018 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 SUPERFAMILY SSF52922 532 666 3.4E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 SMART SM00861 355 526 4.8E-66 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 SUPERFAMILY SSF52518 342 528 6.06E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 665 8.4E-303 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 SUPERFAMILY SSF52518 4 326 6.63E-118 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 Gene3D G3DSA:3.40.50.920 544 665 2.7E-34 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 2.5E-43 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS09335 66dbe4514b6f00ee7a7b912ccc195f60 666 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS23095 7481311c3ad460a57d92b976766e5d71 163 Gene3D G3DSA:3.40.630.30 2 163 4.6E-27 T 29-03-2018 CSW12_RS23095 7481311c3ad460a57d92b976766e5d71 163 Pfam PF00583 Acetyltransferase (GNAT) family 23 137 9.4E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS23095 7481311c3ad460a57d92b976766e5d71 163 SUPERFAMILY SSF55729 1 142 1.54E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 2.2E-78 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 PIRSF PIRSF000116 203 334 6.1E-13 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 PIRSF PIRSF000116 2 206 6.4E-40 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 17 328 9.4E-142 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 Gene3D G3DSA:1.10.1040.10 53 332 1.8E-114 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 SUPERFAMILY SSF48179 185 330 2.61E-69 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 SUPERFAMILY SSF51735 5 184 1.29E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 327 3.4E-65 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS06575 2a2823fca8e0139edbb68b1e0f327d82 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 4 330 45.45 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS17685 b7b32faef6e06144f1668657e3b726ee 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 4 58 1.5E-26 T 29-03-2018 CSW12_RS17685 b7b32faef6e06144f1668657e3b726ee 205 SUPERFAMILY SSF55811 22 200 4.2E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS17685 b7b32faef6e06144f1668657e3b726ee 205 Gene3D G3DSA:3.90.79.10 31 202 1.2E-22 T 29-03-2018 CSW12_RS17685 b7b32faef6e06144f1668657e3b726ee 205 Pfam PF00293 NUDIX domain 72 177 1.7E-10 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS02750 d2f71d0684edf31cd4670c310f6ee614 374 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 9 368 1.2E-110 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS02750 d2f71d0684edf31cd4670c310f6ee614 374 Pfam PF03845 Spore germination protein 13 333 2.0E-57 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 Gene3D G3DSA:3.30.565.10 342 484 6.8E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 SUPERFAMILY SSF55874 318 483 1.44E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 Gene3D G3DSA:1.10.287.130 240 323 8.6E-14 T 29-03-2018 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 483 2.4E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 SMART SM00387 373 484 4.2E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 SMART SM00304 209 261 6.3E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 327 1.1E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 SMART SM00388 262 328 1.9E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 SUPERFAMILY SSF47384 246 329 4.51E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 482 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 438 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 424 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 463 3.2E-19 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01635 94f2df8aae17dce82cb1f424ac339dcd 484 SUPERFAMILY SSF158472 209 257 2.62E-6 T 29-03-2018 CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 Pfam PF00411 Ribosomal protein S11 19 128 1.4E-51 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.503 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 3.0E-59 T 29-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 SUPERFAMILY SSF53137 14 129 3.86E-50 T 29-03-2018 CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 29-03-2018 IPR018102 Ribosomal S11, conserved site CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 PIRSF PIRSF002131 1 129 4.2E-54 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28115 01af3b4a61a994c42ec31f1cbad3bf40 129 Gene3D G3DSA:3.30.420.80 5 129 8.0E-45 T 29-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CSW12_RS05460 1c455ba931e4e8638b972eb96581b800 311 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 278 1.2E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS05460 1c455ba931e4e8638b972eb96581b800 311 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS05460 1c455ba931e4e8638b972eb96581b800 311 Pfam PF00005 ABC transporter 29 181 4.8E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS05460 1c455ba931e4e8638b972eb96581b800 311 SMART SM00382 37 231 4.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05460 1c455ba931e4e8638b972eb96581b800 311 Gene3D G3DSA:3.40.50.300 5 302 1.1E-79 T 29-03-2018 CSW12_RS05460 1c455ba931e4e8638b972eb96581b800 311 SUPERFAMILY SSF52540 8 253 2.66E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09195 667882db8e3685677b663f8f39f7fc0b 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CSW12_RS09195 667882db8e3685677b663f8f39f7fc0b 387 Gene3D G3DSA:3.40.50.1970 9 183 3.3E-49 T 29-03-2018 CSW12_RS09195 667882db8e3685677b663f8f39f7fc0b 387 SUPERFAMILY SSF56796 1 385 3.4E-118 T 29-03-2018 CSW12_RS09195 667882db8e3685677b663f8f39f7fc0b 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 29-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CSW12_RS09195 667882db8e3685677b663f8f39f7fc0b 387 Gene3D G3DSA:1.20.1090.10 184 387 3.0E-47 T 29-03-2018 CSW12_RS09195 667882db8e3685677b663f8f39f7fc0b 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 378 3.8E-101 T 29-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 Pfam PF00239 Resolvase, N terminal domain 3 137 5.2E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 Gene3D G3DSA:3.40.50.1390 2 106 6.8E-33 T 29-03-2018 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 Pfam PF02796 Helix-turn-helix domain of resolvase 140 183 1.6E-13 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 SUPERFAMILY SSF53041 2 137 3.27E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 SMART SM00857 2 138 8.9E-59 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 Gene3D G3DSA:1.10.10.60 134 183 1.5E-11 T 29-03-2018 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 Gene3D G3DSA:1.20.5.40 107 133 4.8E-17 T 29-03-2018 CSW12_RS29545 90662d8dbbeea510fc88992d3e68a2cf 183 SUPERFAMILY SSF46689 140 181 7.26E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS09705 f738b35eb31c0942c4f603490ea0c288 44 Pfam PF08177 Small acid-soluble spore protein N family 1 43 1.8E-21 T 29-03-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 CSW12_RS09705 f738b35eb31c0942c4f603490ea0c288 44 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 44 15.192 T 29-03-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 Gene3D G3DSA:3.40.50.880 34 301 1.1E-50 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 SUPERFAMILY SSF52317 17 297 1.24E-104 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 54.777 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 PIRSF PIRSF000450 1 301 6.5E-147 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 4.5E-134 T 29-03-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.0E-141 T 29-03-2018 IPR033752 MetA family KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46 CSW12_RS26810 c5bfc833cb6ee7aa6b37324605c51e60 301 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 3.0E-148 T 29-03-2018 CSW12_RS30090 a62dbe97f06186bfb56846a4d213fcae 241 Pfam PF10263 SprT-like family 13 115 1.3E-9 T 29-03-2018 IPR006640 SprT-like CSW12_RS30090 a62dbe97f06186bfb56846a4d213fcae 241 Gene3D G3DSA:3.40.390.10 11 150 9.0E-4 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CSW12_RS20730 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 51.776 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CSW12_RS20730 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 PIRSF PIRSF006815 3 447 8.1E-194 T 29-03-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CSW12_RS20730 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Gene3D G3DSA:3.40.640.10 84 336 1.6E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20730 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Gene3D G3DSA:3.90.1150.10 337 447 1.5E-30 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20730 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 Pfam PF02347 Glycine cleavage system P-protein 3 442 7.4E-164 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CSW12_RS20730 bb29a8a551fb12a9a8688f0d8aa8bfc3 447 SUPERFAMILY SSF53383 3 445 1.88E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS16810 5d37ffdeca97d9c309425f844df2d0e2 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 3.9E-103 T 29-03-2018 IPR003797 DegV CSW12_RS16810 5d37ffdeca97d9c309425f844df2d0e2 280 SUPERFAMILY SSF82549 1 279 1.86E-93 T 29-03-2018 CSW12_RS16810 5d37ffdeca97d9c309425f844df2d0e2 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 3.2E-93 T 29-03-2018 IPR003797 DegV CSW12_RS16810 5d37ffdeca97d9c309425f844df2d0e2 280 Gene3D G3DSA:3.40.50.10170 1 153 3.4E-53 T 29-03-2018 CSW12_RS16810 5d37ffdeca97d9c309425f844df2d0e2 280 Gene3D G3DSA:3.30.1180.10 154 279 1.5E-34 T 29-03-2018 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 262 32.322 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 Gene3D G3DSA:3.40.140.10 128 265 1.6E-47 T 29-03-2018 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 Gene3D G3DSA:3.10.20.10 28 109 1.5E-18 T 29-03-2018 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 262 2.1E-72 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 SUPERFAMILY SSF53927 5 261 2.92E-77 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 PIRSF PIRSF015626 1 264 9.4E-80 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS09905 35e8fc7eda7957b0b7db07879bcceaa6 265 Pfam PF02634 FdhD/NarQ family 26 261 3.5E-80 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS14265 1eb993e24b6c94f36d822769feb89727 147 SUPERFAMILY SSF55811 5 125 5.96E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS14265 1eb993e24b6c94f36d822769feb89727 147 PRINTS PR00502 NUDIX hydrolase family signature 46 61 9.8E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS14265 1eb993e24b6c94f36d822769feb89727 147 PRINTS PR00502 NUDIX hydrolase family signature 32 46 9.8E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS14265 1eb993e24b6c94f36d822769feb89727 147 Gene3D G3DSA:3.90.79.10 3 135 4.9E-22 T 29-03-2018 CSW12_RS14265 1eb993e24b6c94f36d822769feb89727 147 Pfam PF00293 NUDIX domain 7 114 3.3E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS14265 1eb993e24b6c94f36d822769feb89727 147 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 336 2.4E-145 T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 Gene3D G3DSA:3.40.50.970 1 354 1.5E-106 T 29-03-2018 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 29-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 Pfam PF02780 Transketolase, C-terminal domain 546 654 2.5E-13 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 Gene3D G3DSA:3.40.50.920 537 661 6.7E-31 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 SUPERFAMILY SSF52922 531 663 3.4E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 Gene3D G3DSA:3.40.50.970 355 536 3.8E-55 T 29-03-2018 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 SMART SM00861 353 524 1.4E-70 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 663 3.6E-275 T 29-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 ProSitePatterns PS00802 Transketolase signature 2. 466 482 - T 29-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 SUPERFAMILY SSF52518 345 525 7.47E-69 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 SUPERFAMILY SSF52518 6 324 4.76E-115 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS11015 458f8f4986febe3bc4174b314aa61e63 664 Pfam PF02779 Transketolase, pyrimidine binding domain 352 523 7.6E-47 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS23490 f077defd433a1e0687397585b7d72c4d 177 Gene3D G3DSA:1.20.144.10 17 172 1.4E-30 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS23490 f077defd433a1e0687397585b7d72c4d 177 SUPERFAMILY SSF48317 11 174 8.5E-41 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS23490 f077defd433a1e0687397585b7d72c4d 177 Pfam PF01569 PAP2 superfamily 62 172 9.5E-23 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS23490 f077defd433a1e0687397585b7d72c4d 177 SMART SM00014 61 169 2.9E-16 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 Gene3D G3DSA:3.40.640.10 69 281 6.0E-21 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 Pfam PF00266 Aminotransferase class-V 85 376 3.0E-18 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 Gene3D G3DSA:3.90.1150.10 282 428 6.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 TIGRFAM TIGR01814 kynureninase: kynureninase 14 413 1.4E-122 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 SUPERFAMILY SSF53383 10 414 2.8E-72 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 Hamap MF_01970 Kynureninase [kynU]. 3 412 39.884 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CSW12_RS13900 2400463de27e8906a73f362eca8f2ebe 428 PIRSF PIRSF038800 6 420 4.5E-152 T 29-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CSW12_RS07820 01626723e6fbe69909174de3ce189e5e 147 Pfam PF00571 CBS domain 86 139 6.6E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS07820 01626723e6fbe69909174de3ce189e5e 147 SUPERFAMILY SSF54631 12 140 5.66E-29 T 29-03-2018 CSW12_RS07820 01626723e6fbe69909174de3ce189e5e 147 Gene3D G3DSA:3.10.580.10 1 147 1.9E-21 T 29-03-2018 CSW12_RS16960 7c52e62e0942fffd0380e5877bbf8391 304 SUPERFAMILY SSF53474 11 304 7.97E-51 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS16960 7c52e62e0942fffd0380e5877bbf8391 304 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 62 73 8.3E-10 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CSW12_RS16960 7c52e62e0942fffd0380e5877bbf8391 304 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 34 42 8.3E-10 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CSW12_RS16960 7c52e62e0942fffd0380e5877bbf8391 304 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 8.3E-10 T 29-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CSW12_RS16960 7c52e62e0942fffd0380e5877bbf8391 304 Gene3D G3DSA:3.40.50.1820 9 304 1.1E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS16960 7c52e62e0942fffd0380e5877bbf8391 304 Pfam PF00561 alpha/beta hydrolase fold 32 291 2.7E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 8.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 8.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 Gene3D G3DSA:1.10.357.10 55 201 6.3E-12 T 29-03-2018 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 SUPERFAMILY SSF46689 3 69 2.51E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 4.6E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 Gene3D G3DSA:1.10.10.60 1 54 1.2E-17 T 29-03-2018 CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS22905 3c93c7707228f344fe38ef21d0dc1c6d 212 SUPERFAMILY SSF48498 77 160 4.13E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS18435 fe3d4c32216d9fa38c33b9e979ce7098 402 SUPERFAMILY SSF58100 282 390 2.56E-97 T 29-03-2018 CSW12_RS18435 fe3d4c32216d9fa38c33b9e979ce7098 402 SUPERFAMILY SSF58100 45 250 2.56E-97 T 29-03-2018 CSW12_RS18435 fe3d4c32216d9fa38c33b9e979ce7098 402 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 54 231 2.9E-66 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS18435 fe3d4c32216d9fa38c33b9e979ce7098 402 Gene3D G3DSA:1.20.1170.10 48 392 9.7E-49 T 29-03-2018 CSW12_RS00435 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 SMART SM00046 4 126 1.3E-9 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CSW12_RS00435 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 Gene3D G3DSA:3.40.50.10330 1 132 1.2E-38 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CSW12_RS00435 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 SUPERFAMILY SSF111331 1 296 2.35E-89 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CSW12_RS00435 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 Pfam PF00781 Diacylglycerol kinase catalytic domain 5 127 4.7E-38 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CSW12_RS00435 789e8ffcfce6c042b6c2e1eccc0fcc4a 301 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 2 294 1.6E-106 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CSW12_RS23840 f8f5c76e8ab78a5556c1fb3c726ec71d 331 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 11 327 1.5E-63 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS23840 f8f5c76e8ab78a5556c1fb3c726ec71d 331 Gene3D G3DSA:1.10.10.60 246 330 5.1E-6 T 29-03-2018 CSW12_RS23840 f8f5c76e8ab78a5556c1fb3c726ec71d 331 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 244 7.5E-65 T 29-03-2018 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.894 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 PIRSF PIRSF001430 1 247 4.2E-84 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 SUPERFAMILY SSF55120 2 247 9.35E-85 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 Gene3D G3DSA:3.30.70.580 1 106 6.1E-32 T 29-03-2018 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 Pfam PF01416 tRNA pseudouridine synthase 144 246 2.0E-34 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 Pfam PF01416 tRNA pseudouridine synthase 8 104 6.3E-9 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 Gene3D G3DSA:3.30.70.660 107 244 1.2E-43 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS28145 e01de89c1aad7fd4e8235a4928512984 247 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 240 1.0E-68 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 Gene3D G3DSA:3.40.50.1100 113 228 2.5E-26 T 29-03-2018 CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 443 263.302 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 106 120 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 Gene3D G3DSA:3.40.50.1100 229 438 1.1E-27 T 29-03-2018 CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 397 1.5E-56 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 SUPERFAMILY SSF53686 48 436 3.02E-59 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18890 8662cab009f961eb4176bd03296971ab 443 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 9 434 1.5E-226 T 29-03-2018 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.631 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 SUPERFAMILY SSF52540 59 395 4.76E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 1.1E-17 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 406 1.9E-212 T 29-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 SMART SM00994 10 49 6.2E-24 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 Pfam PF06689 ClpX C4-type zinc finger 12 48 4.8E-20 T 29-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 SMART SM01086 311 405 3.8E-33 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 SMART SM00382 108 269 4.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 4.0E-51 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 Gene3D G3DSA:1.10.8.60 311 401 2.9E-31 T 29-03-2018 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 Gene3D G3DSA:3.40.50.300 53 309 2.4E-70 T 29-03-2018 CSW12_RS22000 954c6a94789e757c511f3e9397fc6d7a 419 SUPERFAMILY SSF57716 11 46 1.57E-11 T 29-03-2018 CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 11 290 1.7E-66 T 29-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 300 612 7.2E-96 T 29-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 Gene3D G3DSA:1.50.10.20 286 617 4.1E-86 T 29-03-2018 CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 SUPERFAMILY SSF48239 296 615 2.51E-84 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 Gene3D G3DSA:1.50.10.20 32 285 8.2E-39 T 29-03-2018 CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 SUPERFAMILY SSF48239 37 294 2.83E-42 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CSW12_RS09975 bfccbf35c914c30c468397f40e5ea206 617 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 13 613 1.2E-116 T 29-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CSW12_RS13905 e76f0877c6c84ec9f178476412775f65 209 SUPERFAMILY SSF102198 4 206 3.14E-61 T 29-03-2018 CSW12_RS13905 e76f0877c6c84ec9f178476412775f65 209 TIGRFAM TIGR03035 trp_arylform: arylformamidase 6 209 6.9E-100 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CSW12_RS13905 e76f0877c6c84ec9f178476412775f65 209 Pfam PF04199 Putative cyclase 7 152 2.4E-22 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CSW12_RS13905 e76f0877c6c84ec9f178476412775f65 209 Gene3D G3DSA:3.50.30.50 1 207 5.9E-55 T 29-03-2018 CSW12_RS13905 e76f0877c6c84ec9f178476412775f65 209 Hamap MF_01969 Kynurenine formamidase [kynB]. 5 209 43.464 T 29-03-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CSW12_RS14600 332c5fdf12161f7ee4d1e7049ceb402b 427 Gene3D G3DSA:1.20.1250.20 8 211 1.5E-23 T 29-03-2018 CSW12_RS14600 332c5fdf12161f7ee4d1e7049ceb402b 427 SUPERFAMILY SSF103473 19 406 7.19E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS14600 332c5fdf12161f7ee4d1e7049ceb402b 427 Pfam PF07690 Major Facilitator Superfamily 30 243 4.9E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS14600 332c5fdf12161f7ee4d1e7049ceb402b 427 Gene3D G3DSA:1.20.1250.20 214 406 1.6E-20 T 29-03-2018 CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 Gene3D G3DSA:3.40.50.300 1 272 1.3E-74 T 29-03-2018 CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 394 1.2E-151 T 29-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 SUPERFAMILY SSF52540 44 271 6.42E-77 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 SMART SM00116 283 331 0.33 T 29-03-2018 IPR000644 CBS domain CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 SMART SM00116 343 390 0.0032 T 29-03-2018 IPR000644 CBS domain CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 SMART SM00382 54 243 4.8E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 Pfam PF00571 CBS domain 294 329 0.0064 T 29-03-2018 IPR000644 CBS domain CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 Pfam PF00571 CBS domain 338 390 5.6E-4 T 29-03-2018 IPR000644 CBS domain CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 Gene3D G3DSA:3.10.580.10 273 401 9.5E-18 T 29-03-2018 CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 Pfam PF00005 ABC transporter 46 193 1.1E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS13735 44c108ae396dcf4a09d78d393503a6ea 401 SUPERFAMILY SSF54631 280 392 1.21E-20 T 29-03-2018 CSW12_RS13165 aa9e275425c01654c685b5370750e443 159 Pfam PF07301 Protein of unknown function (DUF1453) 7 150 1.6E-43 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CSW12_RS13165 aa9e275425c01654c685b5370750e443 159 PIRSF PIRSF021441 1 159 9.3E-55 T 29-03-2018 IPR031306 CcdC protein CSW12_RS20060 5ca76bf447b6dcb9b02715cff89e8a89 237 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 13 237 2.0E-127 T 29-03-2018 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 Gene3D G3DSA:3.40.190.10 22 144 1.8E-28 T 29-03-2018 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 Pfam PF13416 Bacterial extracellular solute-binding protein 45 311 9.2E-43 T 29-03-2018 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 Gene3D G3DSA:3.40.190.10 145 300 1.1E-43 T 29-03-2018 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PIRSF PIRSF019574 1 348 7.0E-108 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 91 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 167 186 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 293 319 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 106 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 50 71 6.3E-49 T 29-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CSW12_RS05985 7e93cfa87858d423769fe79c68764eba 349 SUPERFAMILY SSF53850 28 345 5.85E-90 T 29-03-2018 CSW12_RS26720 a92a60b2ea2ed506603eb2d665ba0d67 247 Gene3D G3DSA:3.30.70.1030 4 135 1.4E-42 T 29-03-2018 CSW12_RS26720 a92a60b2ea2ed506603eb2d665ba0d67 247 SUPERFAMILY SSF54909 1 246 1.61E-94 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS26720 a92a60b2ea2ed506603eb2d665ba0d67 247 Pfam PF06778 Chlorite dismutase 33 235 1.6E-76 T 29-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CSW12_RS26720 a92a60b2ea2ed506603eb2d665ba0d67 247 Hamap MF_01442 Putative heme-dependent peroxidase . 1 247 57.578 T 29-03-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family CSW12_RS26720 a92a60b2ea2ed506603eb2d665ba0d67 247 Gene3D G3DSA:3.30.70.1100 138 243 3.8E-30 T 29-03-2018 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 Gene3D G3DSA:1.10.10.10 1 83 5.0E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 Gene3D G3DSA:3.40.190.10 87 176 2.5E-18 T 29-03-2018 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 SUPERFAMILY SSF53850 87 295 1.28E-42 T 29-03-2018 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 SUPERFAMILY SSF46785 1 84 1.36E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 Gene3D G3DSA:3.40.190.10 177 267 7.4E-22 T 29-03-2018 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 Pfam PF03466 LysR substrate binding domain 87 292 2.9E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS10520 0d33bdfc51a1d20663ffa45e9aac2122 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.9E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 Gene3D G3DSA:3.40.630.10 1 311 1.9E-62 T 29-03-2018 CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 Pfam PF01546 Peptidase family M20/M25/M40 97 415 1.3E-37 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 SUPERFAMILY SSF53187 334 419 2.73E-62 T 29-03-2018 CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 SUPERFAMILY SSF53187 5 211 2.73E-62 T 29-03-2018 CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 409 1.5E-116 T 29-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 SUPERFAMILY SSF55031 203 310 1.79E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS16495 cd296dd9263584152b85b4d7f4258eb1 422 Pfam PF07687 Peptidase dimerisation domain 202 310 2.1E-17 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.3E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.3E-14 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 Gene3D G3DSA:3.40.50.720 1 49 1.6E-11 T 29-03-2018 CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 Gene3D G3DSA:3.40.50.720 50 235 8.2E-50 T 29-03-2018 CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 SUPERFAMILY SSF51735 2 254 5.68E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 Pfam PF00106 short chain dehydrogenase 8 195 5.2E-61 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20220 a854ca9aebfef4f1b0040ce7363f34b8 264 PIRSF PIRSF000126 2 257 3.0E-58 T 29-03-2018 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Pfam PF01225 Mur ligase family, catalytic domain 4 101 3.0E-22 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 SUPERFAMILY SSF53244 294 428 1.3E-35 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Gene3D G3DSA:3.40.1190.10 90 295 7.7E-41 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Gene3D G3DSA:3.90.190.20 296 436 2.2E-26 T 29-03-2018 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Pfam PF08245 Mur ligase middle domain 106 275 1.6E-23 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 SUPERFAMILY SSF53623 87 293 2.62E-58 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 35.353 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 425 1.1E-134 T 29-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 SUPERFAMILY SSF51984 4 88 5.89E-20 T 29-03-2018 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Gene3D G3DSA:3.40.50.720 4 89 2.3E-4 T 29-03-2018 CSW12_RS23115 aef63d3d65ed47898133d0c435c4137c 436 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 378 2.3E-18 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 Gene3D G3DSA:3.10.170.10 255 404 6.9E-57 T 29-03-2018 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 403 565 1.4E-64 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 257 400 1.1E-52 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 355 375 4.9E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 391 407 4.9E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 480 496 4.9E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 412 423 4.9E-31 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 84 134 4.0E-14 T 29-03-2018 IPR011096 FTP domain CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 SUPERFAMILY SSF55486 256 565 4.4E-105 T 29-03-2018 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 Gene3D G3DSA:1.10.390.10 405 566 1.9E-55 T 29-03-2018 CSW12_RS01715 fa0efe0bfff77fdd5985e41dcaf257da 566 Pfam PF03413 Peptidase propeptide and YPEB domain 151 220 2.3E-8 T 29-03-2018 IPR025711 PepSY domain CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 SUPERFAMILY SSF46955 1 119 2.12E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 Gene3D G3DSA:1.10.1660.10 57 133 6.1E-10 T 29-03-2018 CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 5.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 5.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.6E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 SMART SM00422 2 70 6.6E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 Pfam PF13411 MerR HTH family regulatory protein 2 65 5.6E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS23110 03069ae99479350e951cff5d86f8c79c 137 Gene3D G3DSA:1.10.1660.10 1 56 2.3E-22 T 29-03-2018 CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 Gene3D G3DSA:3.60.20.10 671 790 5.6E-19 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 Gene3D G3DSA:1.10.439.10 26 193 2.4E-54 T 29-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 Pfam PF01804 Penicillin amidase 58 786 1.2E-226 T 29-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 SUPERFAMILY SSF56235 54 790 1.52E-230 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 PIRSF PIRSF001227 15 795 4.9E-211 T 29-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 Gene3D G3DSA:3.60.20.10 349 550 5.3E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 Gene3D G3DSA:1.10.1400.10 551 670 9.0E-23 T 29-03-2018 CSW12_RS11550 27a4650d98168d82a2b594b4c67eff1e 796 Gene3D G3DSA:3.60.20.10 257 348 6.6E-29 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS01205 1c1d43701a48533c67f435645f4dfb89 88 Pfam PF14043 WVELL protein 3 75 2.3E-35 T 29-03-2018 IPR026952 WVELL protein CSW12_RS17680 324ef07ec673c03a80a74144c732c96e 200 Pfam PF09335 SNARE associated Golgi protein 30 156 1.8E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS25935 4a81af71f755745734b3f0aa681b0015 251 SUPERFAMILY SSF55073 131 227 1.8E-5 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS25935 4a81af71f755745734b3f0aa681b0015 251 Pfam PF00990 Diguanylate cyclase, GGDEF domain 132 227 9.0E-5 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS25935 4a81af71f755745734b3f0aa681b0015 251 Gene3D G3DSA:3.30.70.270 107 239 3.7E-6 T 29-03-2018 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Gene3D G3DSA:1.20.1110.10 675 906 2.5E-30 T 29-03-2018 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 382 388 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Gene3D G3DSA:3.40.1110.10 343 547 1.7E-40 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SUPERFAMILY SSF81665 281 374 5.36E-103 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SUPERFAMILY SSF81665 42 145 5.36E-103 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SUPERFAMILY SSF81665 697 905 5.36E-103 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Pfam PF00122 E1-E2 ATPase 164 360 6.1E-45 T 29-03-2018 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 280 400 6.2E-20 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 615 737 1.3E-28 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 26 907 0.0 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SUPERFAMILY SSF81660 348 552 7.19E-41 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 414 427 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 724 735 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 861 882 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 293 309 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 776 792 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 310 329 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 706 721 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 756 769 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 PRINTS PR01836 Magnesium-transporting ATPase signature 811 832 3.8E-82 T 29-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SUPERFAMILY SSF81653 162 280 3.01E-27 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Pfam PF00702 haloacid dehalogenase-like hydrolase 376 662 1.7E-22 T 29-03-2018 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Gene3D G3DSA:2.70.150.10 43 282 1.9E-44 T 29-03-2018 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SUPERFAMILY SSF56784 541 690 1.49E-37 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 SMART SM00831 34 107 3.8E-20 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Gene3D G3DSA:3.40.50.1000 548 674 4.1E-31 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS20270 bc6553d13b99ae267064493447e79907 908 Pfam PF00690 Cation transporter/ATPase, N-terminus 39 102 3.4E-16 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS13570 1c524c2b7602318461bea93fa7e69607 62 Pfam PF13209 Protein of unknown function (DUF4017) 1 60 3.1E-37 T 29-03-2018 IPR025090 Protein of unknown function DUF4017 CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 7.0E-44 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 29-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 SUPERFAMILY SSF89919 3 110 3.14E-37 T 29-03-2018 IPR023799 Ribosome-binding factor A domain CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 Pfam PF02033 Ribosome-binding factor A 4 107 3.7E-35 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 3.0E-44 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 Gene3D G3DSA:3.30.300.20 2 114 2.3E-38 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS08725 2f3d653a796a23fc91c76db9a022e54f 118 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 114 23.044 T 29-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CSW12_RS02470 de6b7faefc0f98358e7142ea930f2d35 185 SUPERFAMILY SSF52096 5 138 3.55E-39 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS02470 de6b7faefc0f98358e7142ea930f2d35 185 Gene3D G3DSA:3.90.226.10 1 152 8.8E-27 T 29-03-2018 CSW12_RS02470 de6b7faefc0f98358e7142ea930f2d35 185 PRINTS PR00127 Clp protease catalytic subunit P signature 8 28 3.1E-7 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS02470 de6b7faefc0f98358e7142ea930f2d35 185 PRINTS PR00127 Clp protease catalytic subunit P signature 115 134 3.1E-7 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS02470 de6b7faefc0f98358e7142ea930f2d35 185 PRINTS PR00127 Clp protease catalytic subunit P signature 39 56 3.1E-7 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS02470 de6b7faefc0f98358e7142ea930f2d35 185 Pfam PF00574 Clp protease 6 138 6.3E-29 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Gene3D G3DSA:3.40.50.980 80 269 3.0E-44 T 29-03-2018 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 85 9.0E-11 T 29-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 530 608 5.9E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Pfam PF00501 AMP-binding enzyme 100 521 3.0E-75 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Gene3D G3DSA:2.30.38.10 440 515 1.6E-5 T 29-03-2018 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 SUPERFAMILY SSF56801 17 635 2.75E-151 T 29-03-2018 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Gene3D G3DSA:3.40.50.980 270 432 1.5E-36 T 29-03-2018 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 Gene3D G3DSA:3.30.300.30 516 623 5.1E-21 T 29-03-2018 CSW12_RS15005 c58e8630ee9a9972fd15e02df4bd635b 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 264 275 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS28025 4d3f43dba4db11a4460bfa8f5c071032 66 Gene3D G3DSA:1.10.287.310 1 63 2.2E-26 T 29-03-2018 CSW12_RS28025 4d3f43dba4db11a4460bfa8f5c071032 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 29-03-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28025 4d3f43dba4db11a4460bfa8f5c071032 66 Pfam PF00831 Ribosomal L29 protein 4 60 2.6E-26 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28025 4d3f43dba4db11a4460bfa8f5c071032 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.5E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28025 4d3f43dba4db11a4460bfa8f5c071032 66 SUPERFAMILY SSF46561 1 64 9.42E-24 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28025 4d3f43dba4db11a4460bfa8f5c071032 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.193 T 29-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 SMART SM00346 2 94 1.4E-13 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 Pfam PF09339 IclR helix-turn-helix domain 4 55 3.8E-15 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 SUPERFAMILY SSF46785 2 77 4.28E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 Gene3D G3DSA:3.30.450.40 92 249 1.4E-32 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 SUPERFAMILY SSF55781 70 244 2.09E-35 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 Pfam PF01614 Bacterial transcriptional regulator 123 240 2.0E-20 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CSW12_RS12725 7cabf754e5e3ec1217ed0bef5fe8046a 249 Gene3D G3DSA:1.10.10.10 1 91 1.7E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08485 27b590500fc863f27e79ec28caedbc1d 62 Pfam PF00830 Ribosomal L28 family 3 58 2.0E-20 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08485 27b590500fc863f27e79ec28caedbc1d 62 Gene3D G3DSA:2.30.170.40 2 61 3.4E-18 T 29-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08485 27b590500fc863f27e79ec28caedbc1d 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 6.8E-23 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08485 27b590500fc863f27e79ec28caedbc1d 62 SUPERFAMILY SSF143800 1 60 3.73E-23 T 29-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08485 27b590500fc863f27e79ec28caedbc1d 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.58 T 29-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-8 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Pfam PF03466 LysR substrate binding domain 88 285 1.2E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Gene3D G3DSA:3.40.190.10 92 175 3.8E-19 T 29-03-2018 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 SUPERFAMILY SSF53850 91 288 6.67E-34 T 29-03-2018 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Gene3D G3DSA:1.10.10.10 1 87 5.0E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 Gene3D G3DSA:3.40.190.10 176 262 1.2E-15 T 29-03-2018 CSW12_RS18265 ef42ec87cf0be72c4b6e0bf0cdafbceb 289 SUPERFAMILY SSF46785 1 111 2.04E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24595 6f8d757a18411006b188146668ea452e 193 SUPERFAMILY SSF52218 1 193 2.01E-60 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS24595 6f8d757a18411006b188146668ea452e 193 Pfam PF02525 Flavodoxin-like fold 1 187 8.2E-54 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS24595 6f8d757a18411006b188146668ea452e 193 Gene3D G3DSA:3.40.50.360 1 193 1.2E-49 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 Gene3D G3DSA:1.10.10.10 2 144 1.9E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 SMART SM00347 30 129 1.8E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 Pfam PF01047 MarR family 40 93 2.3E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 SUPERFAMILY SSF46785 7 144 1.01E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.8E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.8E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11475 5feb51e7007b5d710994ef2d0b5260cd 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.8E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 SUPERFAMILY SSF54814 2 105 1.33E-37 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 Pfam PF07650 KH domain 37 109 2.0E-20 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 SUPERFAMILY SSF54821 107 205 2.88E-37 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.365 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 SMART SM00322 59 124 3.2E-7 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 29-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 Gene3D G3DSA:3.30.300.20 17 106 1.8E-31 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 Gene3D G3DSA:3.30.1140.32 107 206 4.0E-36 T 29-03-2018 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 3.6E-39 T 29-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28015 122c52b97e2cada8071572a9d4cae8d9 219 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.5E-94 T 29-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CSW12_RS07090 cf55fb89b1b6ce3485a588dfd4f73b34 225 Gene3D G3DSA:3.40.50.300 4 221 4.0E-52 T 29-03-2018 CSW12_RS07090 cf55fb89b1b6ce3485a588dfd4f73b34 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 217 6.0E-91 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CSW12_RS07090 cf55fb89b1b6ce3485a588dfd4f73b34 225 SUPERFAMILY SSF52540 6 222 5.25E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07090 cf55fb89b1b6ce3485a588dfd4f73b34 225 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.394 T 29-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CSW12_RS07090 cf55fb89b1b6ce3485a588dfd4f73b34 225 Pfam PF02224 Cytidylate kinase 7 219 1.9E-82 T 29-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CSW12_RS11250 6225bedd59e623d84d7cc5cb89432db9 67 Pfam PF01381 Helix-turn-helix 7 61 7.2E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS11250 6225bedd59e623d84d7cc5cb89432db9 67 Gene3D G3DSA:3.30.1190.10 27 67 1.9E-13 T 29-03-2018 CSW12_RS11250 6225bedd59e623d84d7cc5cb89432db9 67 SUPERFAMILY SSF47413 5 65 5.09E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS11250 6225bedd59e623d84d7cc5cb89432db9 67 SMART SM00530 6 61 1.7E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS11250 6225bedd59e623d84d7cc5cb89432db9 67 Gene3D G3DSA:1.10.10.10 2 26 5.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 SUPERFAMILY SSF103473 541 564 8.11E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 SUPERFAMILY SSF103473 6 188 8.11E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 SUPERFAMILY SSF103473 244 415 8.11E-66 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 8.2E-11 T 29-03-2018 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 8.2E-11 T 29-03-2018 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 8.2E-11 T 29-03-2018 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 8.2E-11 T 29-03-2018 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 Pfam PF07690 Major Facilitator Superfamily 14 405 2.8E-49 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 455 5.0E-75 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 Gene3D G3DSA:1.20.1250.20 255 577 8.6E-26 T 29-03-2018 CSW12_RS18720 fa9ad502146a0368c15dd72c3fd3924e 582 Gene3D G3DSA:1.20.1250.20 4 194 2.3E-31 T 29-03-2018 CSW12_RS09875 05ac68b0fa613e527f8b4b8a9b124f2f 365 Pfam PF03845 Spore germination protein 9 320 5.4E-59 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS09875 05ac68b0fa613e527f8b4b8a9b124f2f 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 362 1.5E-106 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 SUPERFAMILY SSF51419 30 299 5.96E-83 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 34 388 8.2E-16 T 29-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 SUPERFAMILY SSF50621 274 431 6.7E-51 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 39.592 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 3.9E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 3.9E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 3.9E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 3.9E-15 T 29-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 Gene3D G3DSA:2.40.37.10 287 438 6.5E-39 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 1.6E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 1.6E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 1.6E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 1.6E-25 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 10 429 3.9E-153 T 29-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 Gene3D G3DSA:3.20.20.10 38 286 3.0E-61 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS06675 1c33f82ee00faba8f0a40d713322a109 438 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 40 297 1.3E-65 T 29-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 Pfam PF00561 alpha/beta hydrolase fold 33 265 1.6E-23 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 SUPERFAMILY SSF53474 6 276 2.9E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 254 276 1.1E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 221 237 1.1E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 39 57 1.1E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.1E-8 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 2.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 2.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 2.2E-13 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24310 88e5bbbe2dbbd8403b73dcdac53d7464 279 Gene3D G3DSA:3.40.50.1820 3 279 3.1E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS22885 75ea2fa31084872f70f6ddb7c12983e1 380 SUPERFAMILY SSF53383 1 372 1.16E-100 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS22885 75ea2fa31084872f70f6ddb7c12983e1 380 PIRSF PIRSF005572 1 378 1.9E-115 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CSW12_RS22885 75ea2fa31084872f70f6ddb7c12983e1 380 Gene3D G3DSA:3.90.1150.10 250 364 1.2E-28 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS22885 75ea2fa31084872f70f6ddb7c12983e1 380 Gene3D G3DSA:3.40.640.10 11 249 2.7E-51 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS22885 75ea2fa31084872f70f6ddb7c12983e1 380 Pfam PF00266 Aminotransferase class-V 2 364 7.6E-75 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS09940 3b6ce9d89c060b0fada876ef6ca6ddbf 78 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 78 7.9E-23 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CSW12_RS09940 3b6ce9d89c060b0fada876ef6ca6ddbf 78 SUPERFAMILY SSF54285 1 78 2.18E-16 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CSW12_RS09940 3b6ce9d89c060b0fada876ef6ca6ddbf 78 Gene3D G3DSA:3.10.20.30 2 78 9.1E-18 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS09940 3b6ce9d89c060b0fada876ef6ca6ddbf 78 Pfam PF02597 ThiS family 4 78 2.2E-18 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CSW12_RS22345 629ed2fc389bf0218468fd8be0b0d773 152 Pfam PF05031 Iron Transport-associated domain 32 147 9.6E-39 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22345 629ed2fc389bf0218468fd8be0b0d773 152 SUPERFAMILY SSF158911 27 152 3.27E-43 T 29-03-2018 CSW12_RS22345 629ed2fc389bf0218468fd8be0b0d773 152 SMART SM00725 33 152 7.9E-36 T 29-03-2018 IPR006635 NEAT domain CSW12_RS16925 17e6c47002b35dca22effb59defdc8b7 157 SUPERFAMILY SSF118196 1 151 7.85E-45 T 29-03-2018 IPR023370 TsaA-like domain CSW12_RS16925 17e6c47002b35dca22effb59defdc8b7 157 Gene3D G3DSA:2.40.30.70 3 148 3.0E-40 T 29-03-2018 IPR023370 TsaA-like domain CSW12_RS16925 17e6c47002b35dca22effb59defdc8b7 157 Pfam PF01980 Uncharacterised protein family UPF0066 24 130 2.3E-30 T 29-03-2018 IPR023370 TsaA-like domain CSW12_RS28055 3a58915a4d26a51e2837a10f56cbee63 132 SUPERFAMILY SSF56047 2 132 3.27E-49 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28055 3a58915a4d26a51e2837a10f56cbee63 132 Gene3D G3DSA:3.30.1370.30 1 67 4.0E-28 T 29-03-2018 CSW12_RS28055 3a58915a4d26a51e2837a10f56cbee63 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28055 3a58915a4d26a51e2837a10f56cbee63 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.966 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28055 3a58915a4d26a51e2837a10f56cbee63 132 Gene3D G3DSA:3.30.1490.10 76 131 6.1E-22 T 29-03-2018 CSW12_RS28055 3a58915a4d26a51e2837a10f56cbee63 132 Pfam PF00410 Ribosomal protein S8 5 132 3.9E-54 T 29-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS11145 44ad8c47334624abe3aed24b560b4a03 251 Pfam PF13489 Methyltransferase domain 43 148 1.3E-17 T 29-03-2018 CSW12_RS11145 44ad8c47334624abe3aed24b560b4a03 251 Gene3D G3DSA:3.40.50.150 35 251 1.5E-33 T 29-03-2018 CSW12_RS11145 44ad8c47334624abe3aed24b560b4a03 251 SUPERFAMILY SSF53335 13 221 5.73E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS00920 786d8c02bf87963e27c579cd2a482fa5 360 Gene3D G3DSA:1.20.5.340 24 155 0.15 T 29-03-2018 CSW12_RS00920 786d8c02bf87963e27c579cd2a482fa5 360 Pfam PF05816 Toxic anion resistance protein (TelA) 31 359 2.0E-102 T 29-03-2018 IPR008863 Toxic anion resistance CSW12_RS00920 786d8c02bf87963e27c579cd2a482fa5 360 PIRSF PIRSF026508 1 360 3.5E-125 T 29-03-2018 IPR008863 Toxic anion resistance CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.6E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.6E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 SUPERFAMILY SSF46785 6 77 4.17E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 Gene3D G3DSA:3.90.1150.10 357 477 3.5E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 SMART SM00345 17 76 7.0E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 8.2E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 Gene3D G3DSA:1.10.10.10 4 78 9.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 Pfam PF00155 Aminotransferase class I and II 118 460 4.5E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 SUPERFAMILY SSF53383 108 475 5.98E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS09000 a541228751b6ff5a26d543b0f8619149 477 Gene3D G3DSA:3.40.640.10 141 356 9.1E-46 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS04415 ff8319d56c78abf854559a925d7ba8e5 325 Gene3D G3DSA:3.10.180.10 156 318 1.9E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS04415 ff8319d56c78abf854559a925d7ba8e5 325 Gene3D G3DSA:3.10.180.10 1 155 4.3E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS04415 ff8319d56c78abf854559a925d7ba8e5 325 SUPERFAMILY SSF54593 3 303 6.67E-46 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS04415 ff8319d56c78abf854559a925d7ba8e5 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 167 264 5.1E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS04415 ff8319d56c78abf854559a925d7ba8e5 325 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 123 2.0E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS20895 e21aa1879d4633a59b3522185dbf6f06 387 Gene3D G3DSA:3.90.1150.10 248 384 1.2E-42 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20895 e21aa1879d4633a59b3522185dbf6f06 387 SUPERFAMILY SSF53383 16 379 2.53E-108 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS20895 e21aa1879d4633a59b3522185dbf6f06 387 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS20895 e21aa1879d4633a59b3522185dbf6f06 387 PIRSF PIRSF001434 2 382 2.4E-141 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS20895 e21aa1879d4633a59b3522185dbf6f06 387 Gene3D G3DSA:3.40.640.10 3 247 6.7E-56 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20895 e21aa1879d4633a59b3522185dbf6f06 387 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 378 1.1E-145 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS30850 39446cb1455b8f4235a882407db7d980 87 Gene3D G3DSA:2.30.30.100 5 66 1.8E-13 T 29-03-2018 CSW12_RS30850 39446cb1455b8f4235a882407db7d980 87 Pfam PF17209 Hfq protein 6 65 7.3E-8 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS30850 39446cb1455b8f4235a882407db7d980 87 SUPERFAMILY SSF50182 6 66 1.63E-6 T 29-03-2018 IPR010920 LSM domain CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 SUPERFAMILY SSF56978 44 511 1.02E-204 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Gene3D G3DSA:3.30.1040.20 384 398 0.15 T 29-03-2018 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Gene3D G3DSA:2.60.40.1430 405 508 2.6E-42 T 29-03-2018 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Pfam PF17440 Thiol-activated cytolysin beta sandwich domain 406 506 1.3E-40 T 29-03-2018 IPR035390 Thiol-activated cytolysin C-terminal CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Gene3D G3DSA:3.90.840.10 96 297 7.7E-60 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Gene3D G3DSA:3.90.840.10 298 383 1.5E-16 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Pfam PF01289 Thiol-activated cytolysin 51 402 1.8E-145 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 116 132 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 190 205 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 271 294 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 324 341 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 486 506 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 372 399 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 411 428 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 428 444 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 132 150 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 58 75 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 88 110 1.1E-103 T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 ProSitePatterns PS00481 Thiol-activated cytolysins signature. 470 481 - T 29-03-2018 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 CSW12_RS25265 604703f93ee03efd13f8ab853eeccfe7 512 Gene3D G3DSA:3.30.1040.20 68 95 2.7E-19 T 29-03-2018 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 Pfam PF02743 Cache domain 41 263 1.9E-26 T 29-03-2018 IPR033479 Double Cache domain 1 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 Pfam PF00672 HAMP domain 302 349 4.7E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 SUPERFAMILY SSF103190 90 186 3.92E-12 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 Gene3D G3DSA:1.10.287.950 410 658 6.2E-56 T 29-03-2018 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 SMART SM00304 301 353 5.8E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 SMART SM00304 598 654 11.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 SUPERFAMILY SSF58104 388 657 7.32E-74 T 29-03-2018 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 SUPERFAMILY SSF58104 321 355 7.32E-74 T 29-03-2018 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 Gene3D G3DSA:1.10.287.950 315 409 3.7E-7 T 29-03-2018 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 SMART SM00283 382 657 2.0E-78 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 Gene3D G3DSA:3.30.450.20 89 193 5.1E-23 T 29-03-2018 CSW12_RS01500 435339c0effe62f8ed1099c82d472ba0 658 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 429 608 9.5E-46 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 360 426 2.6E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SUPERFAMILY SSF55785 233 352 3.05E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Pfam PF00989 PAS fold 245 351 1.1E-12 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Gene3D G3DSA:3.30.450.20 29 158 5.6E-9 T 29-03-2018 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SUPERFAMILY SSF158472 188 235 1.7E-7 T 29-03-2018 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 3.0E-21 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 523 3.0E-21 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 3.0E-21 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 537 3.0E-21 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SUPERFAMILY SSF55874 416 582 1.02E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Gene3D G3DSA:3.30.450.20 241 365 2.8E-19 T 29-03-2018 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 582 5.9E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SUPERFAMILY SSF47384 346 427 8.63E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SMART SM00091 244 311 4.2E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SMART SM00388 360 427 2.8E-22 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Pfam PF16736 Single Cache-like 33 149 2.4E-32 T 29-03-2018 IPR031967 PhoR, single Cache-like domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Gene3D G3DSA:1.10.287.130 366 423 2.1E-19 T 29-03-2018 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SMART SM00304 185 237 3.8E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 Gene3D G3DSA:3.30.565.10 431 587 6.1E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 SMART SM00387 472 584 6.5E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS22560 5fcaab892cfcda24b025cd8057b19b26 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 242 360 2.4E-10 T 29-03-2018 IPR000014 PAS domain CSW12_RS14055 859fb2c713919e864d4bc4fc43ea7adc 318 SUPERFAMILY SSF53474 36 307 2.01E-72 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS14055 859fb2c713919e864d4bc4fc43ea7adc 318 Gene3D G3DSA:3.40.50.1820 1 317 8.1E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS14055 859fb2c713919e864d4bc4fc43ea7adc 318 Pfam PF07859 alpha/beta hydrolase fold 78 285 1.8E-63 T 29-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CSW12_RS23700 1ccc53e1c19c2bbecc9a8b2b73954522 78 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 65 7.0E-24 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CSW12_RS23700 1ccc53e1c19c2bbecc9a8b2b73954522 78 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 1.6E-36 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CSW12_RS23700 1ccc53e1c19c2bbecc9a8b2b73954522 78 SMART SM01234 1 68 1.8E-50 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CSW12_RS23700 1ccc53e1c19c2bbecc9a8b2b73954522 78 Pfam PF01809 Haemolytic domain 2 68 4.8E-33 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CSW12_RS23700 1ccc53e1c19c2bbecc9a8b2b73954522 78 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.387 T 29-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CSW12_RS11870 97412300831577727c7659f404ab6686 457 Gene3D G3DSA:3.30.565.10 303 457 3.5E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11870 97412300831577727c7659f404ab6686 457 Pfam PF00672 HAMP domain 177 225 5.8E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS11870 97412300831577727c7659f404ab6686 457 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 296 4.8E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11870 97412300831577727c7659f404ab6686 457 SMART SM00387 342 455 7.7E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11870 97412300831577727c7659f404ab6686 457 SUPERFAMILY SSF55874 286 453 2.23E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11870 97412300831577727c7659f404ab6686 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 7.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11870 97412300831577727c7659f404ab6686 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 7.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11870 97412300831577727c7659f404ab6686 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 7.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11870 97412300831577727c7659f404ab6686 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 7.3E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11870 97412300831577727c7659f404ab6686 457 SUPERFAMILY SSF47384 213 297 2.35E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11870 97412300831577727c7659f404ab6686 457 SMART SM00304 174 229 1.3E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS11870 97412300831577727c7659f404ab6686 457 SUPERFAMILY SSF158472 176 227 8.11E-5 T 29-03-2018 CSW12_RS11870 97412300831577727c7659f404ab6686 457 SMART SM00388 230 296 4.6E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11870 97412300831577727c7659f404ab6686 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 454 1.7E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11870 97412300831577727c7659f404ab6686 457 Gene3D G3DSA:1.10.287.130 220 292 6.0E-15 T 29-03-2018 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 244 390 2.0E-43 T 29-03-2018 IPR032810 CCA-adding enzyme, C-terminal CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 168 226 1.2E-16 T 29-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 Gene3D G3DSA:3.30.460.10 3 140 8.5E-44 T 29-03-2018 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 Gene3D G3DSA:1.10.3090.10 141 394 6.6E-39 T 29-03-2018 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 Pfam PF01743 Poly A polymerase head domain 21 140 7.6E-34 T 29-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 SUPERFAMILY SSF81301 5 138 4.03E-40 T 29-03-2018 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 Hamap MF_01263 CCA-adding enzyme [cca]. 1 395 42.21 T 29-03-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 CSW12_RS19915 70322058f1c0a236a9988d8ab1843c78 397 SUPERFAMILY SSF81891 140 393 6.02E-51 T 29-03-2018 CSW12_RS03750 a40729f0da5e463489f7833b8d8c0a6b 362 Gene3D G3DSA:3.40.50.2000 165 330 2.9E-8 T 29-03-2018 CSW12_RS03750 a40729f0da5e463489f7833b8d8c0a6b 362 Pfam PF04230 Polysaccharide pyruvyl transferase 13 287 9.2E-52 T 29-03-2018 IPR007345 Polysaccharide pyruvyl transferase CSW12_RS03750 a40729f0da5e463489f7833b8d8c0a6b 362 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 2 305 1.5E-100 T 29-03-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB CSW12_RS03750 a40729f0da5e463489f7833b8d8c0a6b 362 SUPERFAMILY SSF53756 13 284 9.26E-14 T 29-03-2018 CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 Hamap MF_02040 Iron-sulfur cluster carrier protein. 99 346 31.803 T 29-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 Pfam PF01883 Iron-sulfur cluster assembly protein 5 72 1.2E-17 T 29-03-2018 IPR002744 MIP18 family-like CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 ProSitePatterns PS01215 Mrp family signature. 215 231 - T 29-03-2018 IPR000808 Mrp, conserved site GO:0005524 CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 113 344 1.4E-82 T 29-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 SUPERFAMILY SSF117916 1 94 4.9E-20 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 Gene3D G3DSA:3.40.50.300 97 326 1.1E-47 T 29-03-2018 CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 SUPERFAMILY SSF52540 112 346 1.56E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09945 0eb58215f1c6376db55ab9a58019d86c 349 Gene3D G3DSA:3.30.300.130 1 96 8.2E-23 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 4.9E-33 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 29-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.712 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 4.2E-42 T 29-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 Pfam PF00467 KOW motif 5 36 2.8E-6 T 29-03-2018 IPR005824 KOW CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 SMART SM00739 2 29 4.8E-4 T 29-03-2018 IPR005824 KOW CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 Gene3D G3DSA:2.30.30.30 1 91 3.6E-40 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CSW12_RS28040 58eb0371898030313e2cb82b106fae0f 103 SUPERFAMILY SSF50104 1 99 1.96E-40 T 29-03-2018 IPR008991 Translation protein SH3-like domain CSW12_RS11165 a0f22db4659931f7835c121b9883d113 152 Pfam PF13673 Acetyltransferase (GNAT) domain 46 148 2.4E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS11165 a0f22db4659931f7835c121b9883d113 152 Gene3D G3DSA:3.40.630.30 4 143 3.4E-17 T 29-03-2018 CSW12_RS11165 a0f22db4659931f7835c121b9883d113 152 SUPERFAMILY SSF55729 34 138 2.09E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS18275 25a905124ed7b685f6b7f0dfcc07223b 206 Gene3D G3DSA:2.60.40.680 24 181 9.9E-6 T 29-03-2018 CSW12_RS18275 25a905124ed7b685f6b7f0dfcc07223b 206 Pfam PF07987 Domain of unkown function (DUF1775) 28 148 1.9E-19 T 29-03-2018 IPR012533 YcnI-like CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 SMART SM00347 28 125 6.9E-22 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.3E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 SUPERFAMILY SSF46785 5 135 7.76E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 Gene3D G3DSA:1.10.10.10 1 136 3.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25015 df193cd73eeeae72c45130d6167e0f97 136 Pfam PF01047 MarR family 36 85 2.1E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12255 e90f4a59e5c87434b3a1f5a44f0d8e44 195 Pfam PF13302 Acetyltransferase (GNAT) domain 7 147 6.6E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS12255 e90f4a59e5c87434b3a1f5a44f0d8e44 195 SUPERFAMILY SSF55729 2 173 3.81E-39 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12255 e90f4a59e5c87434b3a1f5a44f0d8e44 195 Gene3D G3DSA:3.40.630.30 1 190 4.2E-26 T 29-03-2018 CSW12_RS26630 aba4cb5ffd9a85de65033940225b35db 290 TIGRFAM TIGR01230 agmatinase: agmatinase 10 286 2.6E-114 T 29-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CSW12_RS26630 aba4cb5ffd9a85de65033940225b35db 290 SUPERFAMILY SSF52768 12 289 8.1E-87 T 29-03-2018 CSW12_RS26630 aba4cb5ffd9a85de65033940225b35db 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CSW12_RS26630 aba4cb5ffd9a85de65033940225b35db 290 PIRSF PIRSF036979 1 290 6.1E-104 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS26630 aba4cb5ffd9a85de65033940225b35db 290 Gene3D G3DSA:3.40.800.10 16 290 7.1E-83 T 29-03-2018 CSW12_RS26630 aba4cb5ffd9a85de65033940225b35db 290 Pfam PF00491 Arginase family 23 285 9.9E-80 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS08250 2a308d20c2bba6ba021251753c5359ed 272 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 35 266 1.1E-55 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CSW12_RS08250 2a308d20c2bba6ba021251753c5359ed 272 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 28 264 1.1E-70 T 29-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CSW12_RS08250 2a308d20c2bba6ba021251753c5359ed 272 Gene3D G3DSA:3.60.140.10 4 271 5.9E-80 T 29-03-2018 CSW12_RS08250 2a308d20c2bba6ba021251753c5359ed 272 SUPERFAMILY SSF64438 10 268 4.94E-79 T 29-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CSW12_RS18475 efe71c499dc11679f3448fab6adaa715 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 1.8E-33 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS18475 efe71c499dc11679f3448fab6adaa715 176 SUPERFAMILY SSF55729 1 174 7.7E-51 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS18475 efe71c499dc11679f3448fab6adaa715 176 Gene3D G3DSA:3.40.630.30 2 175 1.8E-29 T 29-03-2018 CSW12_RS26995 a3dd75314a8fae5078e0611708be8d79 522 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 12 493 1.4E-147 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 SUPERFAMILY SSF55620 3 187 2.08E-77 T 29-03-2018 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 41.873 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 Gene3D G3DSA:3.30.1130.10 56 189 6.6E-60 T 29-03-2018 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 Pfam PF01227 GTP cyclohydrolase I 9 186 1.4E-79 T 29-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 29-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 5.5E-77 T 29-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CSW12_RS20045 9c35b383b0f59639f9e4d665d89b4ca5 189 Gene3D G3DSA:1.10.286.10 7 55 5.2E-25 T 29-03-2018 CSW12_RS11980 fe20d970d42199d70eea2a68c83effdc 346 PIRSF PIRSF005508 1 346 1.8E-141 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CSW12_RS11980 fe20d970d42199d70eea2a68c83effdc 346 Pfam PF01758 Sodium Bile acid symporter family 49 245 4.9E-68 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CSW12_RS11980 fe20d970d42199d70eea2a68c83effdc 346 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 4 333 4.1E-143 T 29-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CSW12_RS15625 5cd6a033d1c68752f56e4bc9b98f0f35 326 Pfam PF06013 Proteins of 100 residues with WXG 3 86 1.3E-13 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS15625 5cd6a033d1c68752f56e4bc9b98f0f35 326 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 3 89 3.2E-16 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS15625 5cd6a033d1c68752f56e4bc9b98f0f35 326 SUPERFAMILY SSF140453 3 93 8.37E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS15625 5cd6a033d1c68752f56e4bc9b98f0f35 326 Gene3D G3DSA:1.10.287.850 1 92 2.1E-9 T 29-03-2018 CSW12_RS23170 9d846756fd6509f4eed5d57a01bb5560 284 Pfam PF00753 Metallo-beta-lactamase superfamily 55 232 2.3E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS23170 9d846756fd6509f4eed5d57a01bb5560 284 SMART SM00849 50 257 1.7E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS23170 9d846756fd6509f4eed5d57a01bb5560 284 Gene3D G3DSA:3.60.15.10 4 269 1.1E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS23170 9d846756fd6509f4eed5d57a01bb5560 284 SUPERFAMILY SSF56281 3 263 1.25E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 Gene3D G3DSA:3.30.70.270 140 309 6.8E-57 T 29-03-2018 CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 SMART SM00267 135 302 1.2E-55 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 Gene3D G3DSA:3.40.50.10600 10 132 6.6E-32 T 29-03-2018 CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 Gene3D G3DSA:3.20.20.450 310 566 1.0E-93 T 29-03-2018 IPR001633 EAL domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 Pfam PF13426 PAS domain 26 126 3.9E-16 T 29-03-2018 IPR000014 PAS domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 Pfam PF00563 EAL domain 319 553 3.4E-70 T 29-03-2018 IPR001633 EAL domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 Pfam PF00990 Diguanylate cyclase, GGDEF domain 146 297 3.2E-42 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 SUPERFAMILY SSF141868 319 563 8.37E-85 T 29-03-2018 IPR001633 EAL domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 SUPERFAMILY SSF55785 26 125 2.79E-31 T 29-03-2018 IPR000014 PAS domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 299 3.0E-36 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 SMART SM00052 312 558 2.1E-93 T 29-03-2018 IPR001633 EAL domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 135 4.9E-19 T 29-03-2018 IPR000014 PAS domain CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 SMART SM00086 86 128 9.4E-11 T 29-03-2018 IPR001610 PAC motif CSW12_RS01845 92b9cb2420279de21982b8d7cdc45248 567 SUPERFAMILY SSF55073 151 304 3.84E-46 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 236 3.0E-31 T 29-03-2018 CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 Gene3D G3DSA:3.40.50.720 1 238 3.3E-41 T 29-03-2018 CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.6E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 4.6E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 4.6E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 4.6E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 4.6E-17 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS14875 42564474e65d21ebe4cd9fc88464ff44 238 SUPERFAMILY SSF51735 5 237 6.27E-43 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 Pfam PF07732 Multicopper oxidase 65 175 1.1E-36 T 29-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 ProSitePatterns PS00079 Multicopper oxidases signature 1. 506 526 - T 29-03-2018 IPR033138 Multicopper oxidases, conserved site CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 Gene3D G3DSA:2.60.40.420 402 545 1.8E-38 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 Pfam PF00394 Multicopper oxidase 254 363 8.5E-15 T 29-03-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 ProSitePatterns PS00080 Multicopper oxidases signature 2. 511 522 - T 29-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 SUPERFAMILY SSF49503 405 524 1.73E-36 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 SUPERFAMILY SSF49503 177 215 2.68E-28 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 SUPERFAMILY SSF49503 263 373 2.68E-28 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 SUPERFAMILY SSF49503 49 175 1.94E-38 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 Gene3D G3DSA:2.60.40.420 181 401 2.0E-44 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 Pfam PF07731 Multicopper oxidase 417 527 1.4E-29 T 29-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CSW12_RS18330 5fec63e081cd404632b2268da7605737 546 Gene3D G3DSA:2.60.40.420 11 180 7.8E-38 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS05395 da83c9ec86e80d3b920e4d1714622edd 290 Gene3D G3DSA:3.90.25.10 181 290 0.0014 T 29-03-2018 CSW12_RS05395 da83c9ec86e80d3b920e4d1714622edd 290 SUPERFAMILY SSF51735 12 233 1.05E-21 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS05395 da83c9ec86e80d3b920e4d1714622edd 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 225 2.1E-6 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS05395 da83c9ec86e80d3b920e4d1714622edd 290 Gene3D G3DSA:3.40.50.720 12 180 1.6E-6 T 29-03-2018 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 SUPERFAMILY SSF46689 83 134 1.25E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 Gene3D G3DSA:1.10.10.60 134 191 1.1E-14 T 29-03-2018 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 Pfam PF12833 Helix-turn-helix domain 105 183 4.3E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 136 178 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 SUPERFAMILY SSF57884 8 88 2.22E-31 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 SUPERFAMILY SSF46689 136 185 4.35E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 166 182 1.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 151 166 1.2E-5 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 SMART SM00342 99 182 3.4E-28 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 Gene3D G3DSA:1.10.10.60 80 133 4.5E-18 T 29-03-2018 CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 PIRSF PIRSF000408 3 190 1.3E-85 T 29-03-2018 IPR016220 Methylphosphotriester-DNA alkyltransferase, AdaA CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 Gene3D G3DSA:3.40.10.10 1 77 2.9E-24 T 29-03-2018 IPR035451 Ada-like domain CSW12_RS09090 24dd67290072a7bf729185bd86df53cb 198 Pfam PF02805 Metal binding domain of Ada 12 74 3.1E-30 T 29-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CSW12_RS27495 6df57938637df77cef43629c8a4eeb25 208 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 29-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CSW12_RS27495 6df57938637df77cef43629c8a4eeb25 208 SUPERFAMILY SSF52540 1 206 4.33E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27495 6df57938637df77cef43629c8a4eeb25 208 Gene3D G3DSA:3.40.50.300 1 206 1.6E-51 T 29-03-2018 CSW12_RS27495 6df57938637df77cef43629c8a4eeb25 208 Pfam PF02223 Thymidylate kinase 8 198 5.3E-50 T 29-03-2018 CSW12_RS27495 6df57938637df77cef43629c8a4eeb25 208 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 30.573 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CSW12_RS27495 6df57938637df77cef43629c8a4eeb25 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 1.7E-59 T 29-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 202 1.2E-28 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 Gene3D G3DSA:1.10.3720.10 1 211 6.0E-36 T 29-03-2018 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 SUPERFAMILY SSF53850 233 501 1.11E-74 T 29-03-2018 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 SUPERFAMILY SSF161098 15 198 4.58E-42 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 Gene3D G3DSA:3.40.190.10 223 381 2.6E-35 T 29-03-2018 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 233 498 3.7E-69 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CSW12_RS16570 4b652c8dc211f53120987b43b41b4f97 503 Gene3D G3DSA:3.40.190.10 382 501 2.8E-24 T 29-03-2018 CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 303 5.0E-147 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 Gene3D G3DSA:3.40.50.1100 38 141 3.1E-41 T 29-03-2018 CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 SUPERFAMILY SSF53686 1 304 4.58E-106 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 291 2.7E-71 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 Gene3D G3DSA:3.40.50.1100 142 306 2.9E-57 T 29-03-2018 CSW12_RS27695 8d9b014f46b7391e36739c6bd676f86a 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 303 1.0E-137 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 SUPERFAMILY SSF55979 257 380 3.84E-32 T 29-03-2018 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 6.6E-36 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 Gene3D G3DSA:3.10.150.10 1 129 1.3E-28 T 29-03-2018 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 257 379 8.3E-38 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 Gene3D G3DSA:3.10.150.10 130 259 3.5E-32 T 29-03-2018 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 SUPERFAMILY SSF55979 1 127 8.05E-23 T 29-03-2018 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 254 1.0E-36 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 Gene3D G3DSA:3.10.150.10 260 381 5.0E-28 T 29-03-2018 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 SUPERFAMILY SSF55979 133 254 3.77E-26 T 29-03-2018 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 380 3.0E-124 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 SMART SM00480 17 376 1.7E-164 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS27315 3ad3d2848816ff479e20f2caa6fc23a3 381 PIRSF PIRSF000804 1 381 5.7E-117 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 SUPERFAMILY SSF52540 236 329 1.17E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 SUPERFAMILY SSF52540 56 205 1.17E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 SUPERFAMILY SSF54211 352 533 1.1E-40 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 Gene3D G3DSA:3.30.230.10 330 556 1.2E-50 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 Gene3D G3DSA:3.40.50.300 48 256 7.7E-32 T 29-03-2018 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 443 451 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 351 534 1.9E-32 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 353 369 3.0E-32 T 29-03-2018 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 493 511 3.0E-32 T 29-03-2018 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 98 117 3.0E-32 T 29-03-2018 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 470 489 3.0E-32 T 29-03-2018 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 440 459 3.0E-32 T 29-03-2018 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 6 533 2.1E-279 T 29-03-2018 IPR014251 Sporulation protease LonB CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 SMART SM00382 90 268 1.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 174 189 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 94 267 3.9E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS21995 d32c963d11a955595df598db12f576c6 557 Gene3D G3DSA:1.10.8.60 257 329 2.8E-9 T 29-03-2018 CSW12_RS23060 a62dbb1a6f482df59e2f7384c13a2780 40 Pfam PF01817 Chorismate mutase type II 10 39 1.3E-8 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS23060 a62dbb1a6f482df59e2f7384c13a2780 40 Gene3D G3DSA:1.20.59.10 1 40 1.3E-10 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS23060 a62dbb1a6f482df59e2f7384c13a2780 40 SUPERFAMILY SSF48600 4 38 8.24E-10 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS02100 3b7669fefe232093ee658af549f81628 303 Gene3D G3DSA:1.10.10.630 166 237 1.1E-15 T 29-03-2018 IPR034829 DnaD-like domain CSW12_RS02100 3b7669fefe232093ee658af549f81628 303 SUPERFAMILY SSF158499 169 231 9.42E-13 T 29-03-2018 IPR006343 DnaD domain CSW12_RS02100 3b7669fefe232093ee658af549f81628 303 Pfam PF07261 Replication initiation and membrane attachment 176 237 1.3E-12 T 29-03-2018 IPR006343 DnaD domain CSW12_RS02100 3b7669fefe232093ee658af549f81628 303 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 176 236 3.3E-15 T 29-03-2018 IPR006343 DnaD domain CSW12_RS00905 edd9b7270ee4a206e71bdf555d4ea659 192 Gene3D G3DSA:2.60.60.30 18 187 3.9E-65 T 29-03-2018 CSW12_RS00905 edd9b7270ee4a206e71bdf555d4ea659 192 Pfam PF02342 TerD domain 1 188 8.3E-85 T 29-03-2018 IPR003325 TerD domain GO:0006950 CSW12_RS27985 ec879859a6ca8ca9fa4844a9f1adb622 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.709 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27985 ec879859a6ca8ca9fa4844a9f1adb622 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 7.4E-89 T 29-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27985 ec879859a6ca8ca9fa4844a9f1adb622 210 Pfam PF00297 Ribosomal protein L3 99 181 1.9E-17 T 29-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27985 ec879859a6ca8ca9fa4844a9f1adb622 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 29-03-2018 IPR019926 Ribosomal protein L3, conserved site CSW12_RS27985 ec879859a6ca8ca9fa4844a9f1adb622 210 SUPERFAMILY SSF50447 1 208 4.15E-83 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS27985 ec879859a6ca8ca9fa4844a9f1adb622 210 Gene3D G3DSA:4.10.960.10 58 164 2.5E-35 T 29-03-2018 CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 2.4E-63 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 SUPERFAMILY SSF56784 1 252 2.84E-69 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 6.2E-22 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 29-03-2018 CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 Gene3D G3DSA:3.30.1240.10 96 180 3.4E-29 T 29-03-2018 CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 Gene3D G3DSA:3.40.50.1000 1 95 8.3E-19 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07865 43cceb5f6cd69b2c15bb6f4e60619674 257 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 1.1E-66 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS16870 d4eea64804ad8e902ab921db93c311cc 310 Gene3D G3DSA:3.90.1200.10 51 275 6.2E-19 T 29-03-2018 CSW12_RS16870 d4eea64804ad8e902ab921db93c311cc 310 Pfam PF01636 Phosphotransferase enzyme family 20 243 5.7E-22 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS16870 d4eea64804ad8e902ab921db93c311cc 310 SUPERFAMILY SSF56112 8 260 4.37E-35 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS05950 cb8573275a74c4cd4a9c320157de7e52 107 SUPERFAMILY SSF47406 72 106 9.94E-15 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CSW12_RS05950 cb8573275a74c4cd4a9c320157de7e52 107 SUPERFAMILY SSF47413 2 66 6.48E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS05950 cb8573275a74c4cd4a9c320157de7e52 107 Gene3D G3DSA:1.10.260.40 1 107 5.2E-30 T 29-03-2018 CSW12_RS05950 cb8573275a74c4cd4a9c320157de7e52 107 Pfam PF08671 Anti-repressor SinI 72 99 7.1E-16 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CSW12_RS05950 cb8573275a74c4cd4a9c320157de7e52 107 SMART SM00530 5 61 2.1E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05950 cb8573275a74c4cd4a9c320157de7e52 107 Pfam PF01381 Helix-turn-helix 6 60 1.4E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 29-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 Gene3D G3DSA:3.40.50.720 1 125 4.8E-29 T 29-03-2018 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 4 266 6.0E-85 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 Gene3D G3DSA:3.30.360.10 130 234 1.4E-37 T 29-03-2018 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 264 1.9E-32 T 29-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 128 9.1E-32 T 29-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 SUPERFAMILY SSF55347 129 237 4.36E-38 T 29-03-2018 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 SUPERFAMILY SSF51735 4 155 6.68E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 4 266 29.619 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS19935 3b7b39e922c3c7576cbf06e9aae94d4e 266 PIRSF PIRSF000161 2 266 6.2E-68 T 29-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS14575 de104ab8fb63d3f4d2c296a5f292c57c 192 Gene3D G3DSA:2.60.120.10 3 192 2.8E-22 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS14575 de104ab8fb63d3f4d2c296a5f292c57c 192 SUPERFAMILY SSF51182 8 189 1.14E-31 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS14575 de104ab8fb63d3f4d2c296a5f292c57c 192 Pfam PF05995 Cysteine dioxygenase type I 55 170 6.9E-6 T 29-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CSW12_RS06375 931fdf8578cddf2978537404f78725dc 184 SUPERFAMILY SSF52499 3 182 1.27E-44 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS06375 931fdf8578cddf2978537404f78725dc 184 Pfam PF00857 Isochorismatase family 6 178 7.3E-34 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS06375 931fdf8578cddf2978537404f78725dc 184 Gene3D G3DSA:3.40.50.850 2 184 1.6E-43 T 29-03-2018 CSW12_RS13340 3802da377f96055608183d6e062aa103 250 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 65 230 2.3E-54 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CSW12_RS13340 3802da377f96055608183d6e062aa103 250 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 62 236 7.4E-48 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CSW12_RS13340 3802da377f96055608183d6e062aa103 250 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 245 57.407 T 29-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 SUPERFAMILY SSF55021 260 346 7.56E-14 T 29-03-2018 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 Pfam PF13840 ACT domain 336 398 8.4E-22 T 29-03-2018 IPR027795 GATS-like ACT domain CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 SUPERFAMILY SSF53633 3 246 6.28E-68 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.3E-139 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 Gene3D G3DSA:3.30.70.260 337 408 1.3E-15 T 29-03-2018 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 Gene3D G3DSA:3.30.70.260 240 336 5.5E-17 T 29-03-2018 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 PIRSF PIRSF000726 61 409 6.4E-95 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 PIRSF PIRSF000726 1 65 4.0E-9 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 Gene3D G3DSA:3.40.1160.10 1 239 1.4E-66 T 29-03-2018 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 58 401 3.5E-96 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 SUPERFAMILY SSF55021 335 404 3.44E-17 T 29-03-2018 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08780 a08b83ab49cfa910e656fdda40acf418 410 Pfam PF00696 Amino acid kinase family 2 235 2.2E-47 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 Gene3D G3DSA:3.30.565.10 319 480 1.0E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 323 8.6E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 Gene3D G3DSA:1.10.287.130 249 318 6.9E-10 T 29-03-2018 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 SMART SM00388 258 324 1.9E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 2.4E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 2.4E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 434 2.4E-6 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 SUPERFAMILY SSF47384 244 325 1.26E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 SUPERFAMILY SSF55874 315 478 1.31E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 459 3.5E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS24965 1e6f9f767d5e2a3bb13f8245091b5a1f 480 SMART SM00387 369 480 1.4E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 SUPERFAMILY SSF53383 9 427 1.99E-116 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 Gene3D G3DSA:3.40.640.10 174 314 7.5E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 Gene3D G3DSA:3.90.1150.10 1 161 3.7E-38 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 Gene3D G3DSA:3.90.1150.10 315 427 4.9E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 PIRSF PIRSF000521 16 427 4.3E-42 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS16510 8959336622d0c22cbf56089772427d35 436 Pfam PF00202 Aminotransferase class-III 16 422 3.4E-103 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 SMART SM00863 656 699 8.1E-19 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 8.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 8.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 301 314 8.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 8.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 277 293 8.8E-32 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 699 2.0E-16 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 858 0.0 T 29-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Gene3D G3DSA:3.30.980.10 556 701 4.0E-44 T 29-03-2018 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 SUPERFAMILY SSF101353 246 439 3.79E-68 T 29-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 SUPERFAMILY SSF55681 5 245 1.32E-88 T 29-03-2018 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 SUPERFAMILY SSF50447 457 555 7.77E-17 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 880 184.837 T 29-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Pfam PF02272 DHHA1 domain 736 875 2.1E-30 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Pfam PF01411 tRNA synthetases class II (A) 8 558 1.9E-212 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Gene3D G3DSA:1.20.120.330 702 822 0.0013 T 29-03-2018 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 SUPERFAMILY SSF55186 555 720 5.23E-51 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CSW12_RS21575 5d2bc1f0d52b75663dfd0d9adb3c0c80 880 Gene3D G3DSA:3.30.930.10 3 242 1.3E-97 T 29-03-2018 CSW12_RS08830 1a485b24e88118542c56e4288de0c4c4 352 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 334 1.4E-43 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS08830 1a485b24e88118542c56e4288de0c4c4 352 Gene3D G3DSA:1.10.3470.10 54 341 2.1E-46 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 Pfam PF00375 Sodium:dicarboxylate symporter family 10 392 1.2E-95 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 SUPERFAMILY SSF118215 7 392 1.1E-83 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 PRINTS PR00173 Glutamate-aspartate symporter signature 182 201 8.0E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 8.0E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 PRINTS PR00173 Glutamate-aspartate symporter signature 284 310 8.0E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 PRINTS PR00173 Glutamate-aspartate symporter signature 135 157 8.0E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 PRINTS PR00173 Glutamate-aspartate symporter signature 347 367 8.0E-16 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS25810 a926550683a41fed9cefcbd44608ad1c 405 Gene3D G3DSA:1.10.3860.10 1 398 1.4E-80 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS04780 657e75fe823703955c3a1be11f83bcee 351 Pfam PF13531 Bacterial extracellular solute-binding protein 57 302 3.8E-44 T 29-03-2018 CSW12_RS04780 657e75fe823703955c3a1be11f83bcee 351 SUPERFAMILY SSF53850 44 350 6.95E-93 T 29-03-2018 CSW12_RS04780 657e75fe823703955c3a1be11f83bcee 351 Gene3D G3DSA:3.40.190.10 42 146 8.9E-27 T 29-03-2018 CSW12_RS04780 657e75fe823703955c3a1be11f83bcee 351 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 167 175 - T 29-03-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 CSW12_RS04780 657e75fe823703955c3a1be11f83bcee 351 Gene3D G3DSA:3.40.190.10 147 351 1.9E-49 T 29-03-2018 CSW12_RS04780 657e75fe823703955c3a1be11f83bcee 351 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 42 348 8.5E-153 T 29-03-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CSW12_RS15540 abd318a085b3267097e3d99e14303948 417 Gene3D G3DSA:1.20.1250.20 1 207 5.5E-24 T 29-03-2018 CSW12_RS15540 abd318a085b3267097e3d99e14303948 417 Gene3D G3DSA:1.20.1250.20 209 410 1.8E-20 T 29-03-2018 CSW12_RS15540 abd318a085b3267097e3d99e14303948 417 Pfam PF07690 Major Facilitator Superfamily 19 366 5.1E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS15540 abd318a085b3267097e3d99e14303948 417 SUPERFAMILY SSF103473 12 409 4.84E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 331 341 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 142 153 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 Gene3D G3DSA:3.40.50.200 92 391 2.2E-96 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 Pfam PF00082 Subtilase family 139 373 1.4E-50 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 137 156 8.7E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 330 346 8.7E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 175 188 8.7E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 Gene3D G3DSA:3.30.70.80 32 91 0.0028 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS16130 0925a8514afaf781da6b6cce0b678423 397 SUPERFAMILY SSF52743 119 390 3.27E-92 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS21475 b386156e44093e424423b653a46f1a42 315 Pfam PF01497 Periplasmic binding protein 62 289 9.8E-35 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS21475 b386156e44093e424423b653a46f1a42 315 Gene3D G3DSA:3.40.50.1980 39 153 2.9E-25 T 29-03-2018 CSW12_RS21475 b386156e44093e424423b653a46f1a42 315 SUPERFAMILY SSF53807 42 309 4.71E-58 T 29-03-2018 CSW12_RS21475 b386156e44093e424423b653a46f1a42 315 Gene3D G3DSA:3.40.50.1980 154 310 2.0E-33 T 29-03-2018 CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 Pfam PF07883 Cupin domain 126 182 4.3E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 SUPERFAMILY SSF47413 12 77 9.57E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 SMART SM00530 19 74 2.3E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 Gene3D G3DSA:1.10.260.40 3 89 1.1E-16 T 29-03-2018 CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 Pfam PF01381 Helix-turn-helix 20 72 1.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 Gene3D G3DSA:2.60.120.10 97 188 8.4E-11 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS22115 bc67e9b1ce327cb7c398c9e449558646 190 SUPERFAMILY SSF51182 92 188 1.74E-15 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS00225 316ffc94a092b267173e0455d99a1b95 269 Pfam PF03374 Phage antirepressor protein KilAC domain 151 253 2.1E-30 T 29-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 CSW12_RS00225 316ffc94a092b267173e0455d99a1b95 269 SMART SM01040 14 101 1.4E-35 T 29-03-2018 IPR003497 BRO N-terminal domain CSW12_RS00225 316ffc94a092b267173e0455d99a1b95 269 Pfam PF02498 BRO family, N-terminal domain 15 101 1.8E-22 T 29-03-2018 IPR003497 BRO N-terminal domain CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 7.0E-13 T 29-03-2018 IPR011096 FTP domain CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 402 566 4.0E-50 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 248 399 3.1E-34 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 SUPERFAMILY SSF55486 246 566 4.4E-67 T 29-03-2018 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 Gene3D G3DSA:1.10.390.10 404 567 1.4E-39 T 29-03-2018 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 390 406 2.4E-14 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 411 422 2.4E-14 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 481 497 2.4E-14 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS14030 4c3645539d4992848d78fe40b0bb5964 567 Gene3D G3DSA:3.10.170.10 208 402 9.0E-37 T 29-03-2018 CSW12_RS06600 7fe339fd2a40dcae5f59948b40049534 420 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 13 325 7.2E-104 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CSW12_RS06600 7fe339fd2a40dcae5f59948b40049534 420 Pfam PF13393 Histidyl-tRNA synthetase 11 320 4.9E-72 T 29-03-2018 CSW12_RS06600 7fe339fd2a40dcae5f59948b40049534 420 SUPERFAMILY SSF55681 7 328 1.42E-60 T 29-03-2018 CSW12_RS06600 7fe339fd2a40dcae5f59948b40049534 420 PIRSF PIRSF001549 2 413 2.6E-74 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CSW12_RS06600 7fe339fd2a40dcae5f59948b40049534 420 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 378 36.779 T 29-03-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CSW12_RS06600 7fe339fd2a40dcae5f59948b40049534 420 Gene3D G3DSA:3.30.930.10 1 334 2.5E-62 T 29-03-2018 CSW12_RS17165 248535a04df8c30da4b6118c8ca4f680 202 Gene3D G3DSA:2.60.120.40 54 202 1.5E-24 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS26830 628882cd4a5d7dd0a27646ae41a6a742 223 SUPERFAMILY SSF51206 28 138 3.01E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS26830 628882cd4a5d7dd0a27646ae41a6a742 223 Pfam PF00027 Cyclic nucleotide-binding domain 35 120 4.0E-17 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS26830 628882cd4a5d7dd0a27646ae41a6a742 223 SMART SM00100 15 136 3.1E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS26830 628882cd4a5d7dd0a27646ae41a6a742 223 SUPERFAMILY SSF46785 151 219 1.39E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26830 628882cd4a5d7dd0a27646ae41a6a742 223 Gene3D G3DSA:2.60.120.10 8 150 3.0E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS26830 628882cd4a5d7dd0a27646ae41a6a742 223 Gene3D G3DSA:1.10.10.10 151 222 4.8E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 355 425 5.4E-7 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 SMART SM00382 50 352 9.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Pfam PF07724 AAA domain (Cdc48 subfamily) 192 349 4.6E-41 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 463 9.1E-210 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Gene3D G3DSA:1.10.8.60 355 451 2.4E-31 T 29-03-2018 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 2 463 43.557 T 29-03-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 54 137 3.0E-6 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Gene3D G3DSA:1.10.8.10 222 264 5.2E-17 T 29-03-2018 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 SMART SM01086 355 449 3.2E-23 T 29-03-2018 IPR019489 Clp ATPase, C-terminal CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Gene3D G3DSA:3.40.50.300 7 124 0.0014 T 29-03-2018 CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 SUPERFAMILY SSF52540 6 460 1.71E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08630 24d80dd8a85e8817b79fb7fc5f9c6535 463 Gene3D G3DSA:1.10.8.10 125 221 3.6E-27 T 29-03-2018 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 Gene3D G3DSA:1.10.3130.10 1 53 4.0E-26 T 29-03-2018 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 9.2E-80 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 PIRSF PIRSF000441 1 218 5.5E-87 T 29-03-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 SUPERFAMILY SSF51161 2 168 3.88E-57 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 Gene3D G3DSA:2.160.10.10 54 220 7.0E-40 T 29-03-2018 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.4E-4 T 29-03-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274 CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 3.8E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS27870 e309c7739e02d6c24ab23015bb5ea259 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.0E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS23550 c51677a89bb02b1f5fabcc176e8d9220 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 9.7E-23 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS23550 c51677a89bb02b1f5fabcc176e8d9220 107 Gene3D G3DSA:2.60.300.12 1 105 8.8E-28 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS23550 c51677a89bb02b1f5fabcc176e8d9220 107 SUPERFAMILY SSF89360 1 104 3.92E-24 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS16095 9106745d893188fd06e84f4893d6dfb2 255 SUPERFAMILY SSF52540 6 232 8.87E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16095 9106745d893188fd06e84f4893d6dfb2 255 Gene3D G3DSA:3.40.50.300 1 253 5.0E-65 T 29-03-2018 CSW12_RS16095 9106745d893188fd06e84f4893d6dfb2 255 Pfam PF00005 ABC transporter 26 174 1.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS16095 9106745d893188fd06e84f4893d6dfb2 255 SMART SM00382 35 223 8.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05470 2dd4baa295695a224d6c8e57ff886416 534 Gene3D G3DSA:3.40.190.10 166 298 2.4E-37 T 29-03-2018 CSW12_RS05470 2dd4baa295695a224d6c8e57ff886416 534 SUPERFAMILY SSF53850 26 527 6.21E-123 T 29-03-2018 CSW12_RS05470 2dd4baa295695a224d6c8e57ff886416 534 Gene3D G3DSA:3.10.105.10 299 504 4.1E-45 T 29-03-2018 CSW12_RS05470 2dd4baa295695a224d6c8e57ff886416 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 454 1.1E-79 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS05470 2dd4baa295695a224d6c8e57ff886416 534 PIRSF PIRSF002741 1 533 3.1E-101 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS05470 2dd4baa295695a224d6c8e57ff886416 534 Gene3D G3DSA:3.90.76.10 54 165 1.2E-33 T 29-03-2018 CSW12_RS16200 ebdeb4fc0e3e4ebfe6291d716b8bd1c4 400 Gene3D G3DSA:1.20.1250.20 1 188 8.5E-17 T 29-03-2018 CSW12_RS16200 ebdeb4fc0e3e4ebfe6291d716b8bd1c4 400 Gene3D G3DSA:1.20.1250.20 197 400 8.6E-26 T 29-03-2018 CSW12_RS16200 ebdeb4fc0e3e4ebfe6291d716b8bd1c4 400 Pfam PF07690 Major Facilitator Superfamily 216 391 8.0E-18 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS16200 ebdeb4fc0e3e4ebfe6291d716b8bd1c4 400 SUPERFAMILY SSF103473 8 394 5.89E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 29-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 SMART SM00650 35 211 1.1E-85 T 29-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 Gene3D G3DSA:3.40.50.150 3 219 3.0E-61 T 29-03-2018 CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 SUPERFAMILY SSF53335 16 286 5.23E-77 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 19 280 2.5E-76 T 29-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 19 286 1.3E-88 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 Gene3D G3DSA:1.10.8.100 220 286 8.4E-24 T 29-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CSW12_RS27550 cf13ea748add0df282064a99d3e20b9d 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 19 287 56.956 T 29-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CSW12_RS05050 07fbe97ce02af7ed69c8d3736d890781 72 Gene3D G3DSA:1.10.260.40 5 72 3.1E-13 T 29-03-2018 CSW12_RS05050 07fbe97ce02af7ed69c8d3736d890781 72 Pfam PF01381 Helix-turn-helix 11 63 9.1E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05050 07fbe97ce02af7ed69c8d3736d890781 72 SUPERFAMILY SSF47413 8 66 6.97E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS05050 07fbe97ce02af7ed69c8d3736d890781 72 SMART SM00530 8 63 3.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS23375 eaf207c29c51b1c605a32e19607dc2a0 143 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 14 93 1.0E-23 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CSW12_RS23375 eaf207c29c51b1c605a32e19607dc2a0 143 Gene3D G3DSA:1.10.3420.10 58 137 6.6E-28 T 29-03-2018 CSW12_RS23375 eaf207c29c51b1c605a32e19607dc2a0 143 Gene3D G3DSA:1.10.3420.10 4 57 7.2E-11 T 29-03-2018 CSW12_RS25145 e73676fd0c332133f9a90380dd6b615f 114 Gene3D G3DSA:1.10.10.10 12 106 2.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25145 e73676fd0c332133f9a90380dd6b615f 114 SUPERFAMILY SSF46785 2 105 1.63E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25145 e73676fd0c332133f9a90380dd6b615f 114 Pfam PF01638 HxlR-like helix-turn-helix 14 102 1.5E-39 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS00910 fff91c3c31f1e133181a95dcc1812658 263 Pfam PF03741 Integral membrane protein TerC family 35 216 1.8E-53 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CSW12_RS00910 fff91c3c31f1e133181a95dcc1812658 263 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 245 3.9E-80 T 29-03-2018 IPR022493 Integral membrane YkoY CSW12_RS00910 fff91c3c31f1e133181a95dcc1812658 263 SUPERFAMILY SSF103473 30 242 1.44E-6 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 7.7E-11 T 29-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 Gene3D G3DSA:3.40.50.10730 173 291 7.6E-23 T 29-03-2018 CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.5E-30 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 Gene3D G3DSA:3.90.180.10 1 172 2.6E-47 T 29-03-2018 CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 Pfam PF00107 Zinc-binding dehydrogenase 188 255 2.2E-10 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 SUPERFAMILY SSF50129 1 176 8.52E-61 T 29-03-2018 IPR011032 GroES-like CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 SUPERFAMILY SSF51735 155 338 3.54E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS12185 a5f1ae66c82b8047f52ce67d1ed4a4cd 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 PIRSF PIRSF001365 1 292 5.3E-97 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 29-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 29-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 Gene3D G3DSA:3.20.20.70 2 292 3.4E-101 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 SMART SM01130 3 291 1.1E-137 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 289 2.4E-109 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 2.1E-107 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 4.9E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 4.9E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 4.9E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 4.9E-33 T 29-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 SUPERFAMILY SSF51569 2 289 1.78E-102 T 29-03-2018 CSW12_RS08785 991054d214f60afa3fec02f01ffdae57 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 63.312 T 29-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CSW12_RS22840 f1eac589e7f34d4e0db5f60de7dddede 267 SUPERFAMILY SSF111331 6 266 7.03E-56 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CSW12_RS22840 f1eac589e7f34d4e0db5f60de7dddede 267 Gene3D G3DSA:2.60.200.30 123 245 3.4E-24 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CSW12_RS22840 f1eac589e7f34d4e0db5f60de7dddede 267 Gene3D G3DSA:3.40.50.10330 7 122 9.4E-14 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CSW12_RS22840 f1eac589e7f34d4e0db5f60de7dddede 267 Pfam PF01513 ATP-NAD kinase 39 252 2.1E-16 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CSW12_RS22840 f1eac589e7f34d4e0db5f60de7dddede 267 Hamap MF_00361 NAD kinase [nadK]. 5 264 20.08 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CSW12_RS18390 0e8eb59999fe494fee615f490a9af0e1 103 Pfam PF01906 Putative heavy-metal-binding 1 103 1.3E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS18390 0e8eb59999fe494fee615f490a9af0e1 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.378 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS18390 0e8eb59999fe494fee615f490a9af0e1 103 SUPERFAMILY SSF117782 1 103 6.54E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS18390 0e8eb59999fe494fee615f490a9af0e1 103 Gene3D G3DSA:3.30.110.70 1 103 1.7E-34 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 ProSitePatterns PS00786 5'-nucleotidase signature 2. 131 142 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 Pfam PF02872 5'-nucleotidase, C-terminal domain 373 566 1.1E-19 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 PRINTS PR01607 Apyrase family signature 446 469 2.8E-22 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 PRINTS PR01607 Apyrase family signature 244 261 2.8E-22 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 PRINTS PR01607 Apyrase family signature 38 56 2.8E-22 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 PRINTS PR01607 Apyrase family signature 299 319 2.8E-22 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 PRINTS PR01607 Apyrase family signature 547 566 2.8E-22 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 PRINTS PR01607 Apyrase family signature 273 296 2.8E-22 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 Pfam PF00149 Calcineurin-like phosphoesterase 40 290 4.8E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 Gene3D G3DSA:3.60.21.10 29 370 3.6E-69 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 SUPERFAMILY SSF56300 36 381 6.81E-76 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 747 777 1.1E-5 T 29-03-2018 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 SUPERFAMILY SSF55816 373 610 5.49E-40 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 Pfam PF00746 LPXTG cell wall anchor motif 740 778 1.6E-6 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CSW12_RS20165 df5a7916d663f07ca5e8ca3fced14da5 780 Gene3D G3DSA:3.90.780.10 371 610 3.3E-53 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14455 b01ec978c7eabb87cddeacf56a23a607 156 SUPERFAMILY SSF55811 8 151 1.49E-34 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS14455 b01ec978c7eabb87cddeacf56a23a607 156 Pfam PF00293 NUDIX domain 25 142 1.0E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS14455 b01ec978c7eabb87cddeacf56a23a607 156 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS14455 b01ec978c7eabb87cddeacf56a23a607 156 Gene3D G3DSA:3.90.79.10 2 153 1.1E-30 T 29-03-2018 CSW12_RS14455 b01ec978c7eabb87cddeacf56a23a607 156 PRINTS PR00502 NUDIX hydrolase family signature 61 76 2.6E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS14455 b01ec978c7eabb87cddeacf56a23a607 156 PRINTS PR00502 NUDIX hydrolase family signature 47 61 2.6E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS07450 2de40813a20aae90d71eee025550d74b 125 Pfam PF13054 Protein of unknown function (DUF3915) 5 123 1.7E-61 T 29-03-2018 IPR025026 Protein of unknown function DUF3915 CSW12_RS06200 2d23d212c79c699ab6e1f7f2ba61e9f3 209 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 193 2.8E-20 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS06200 2d23d212c79c699ab6e1f7f2ba61e9f3 209 Gene3D G3DSA:3.40.225.10 5 208 7.5E-23 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS06200 2d23d212c79c699ab6e1f7f2ba61e9f3 209 SUPERFAMILY SSF53639 7 204 7.65E-28 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS06200 2d23d212c79c699ab6e1f7f2ba61e9f3 209 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 204 70.059 T 29-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CSW12_RS06200 2d23d212c79c699ab6e1f7f2ba61e9f3 209 SMART SM01007 9 196 1.0E-15 T 29-03-2018 IPR001303 Class II aldolase/adducin N-terminal CSW12_RS29570 8026465e9e102fedbaf4c277d7c9626f 228 Pfam PF13610 DDE domain 72 205 9.2E-44 T 29-03-2018 IPR032874 DDE domain CSW12_RS29570 8026465e9e102fedbaf4c277d7c9626f 228 Gene3D G3DSA:3.30.420.10 63 223 1.8E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29570 8026465e9e102fedbaf4c277d7c9626f 228 SUPERFAMILY SSF53098 71 185 2.53E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29530 8026465e9e102fedbaf4c277d7c9626f 228 Pfam PF13610 DDE domain 72 205 9.2E-44 T 29-03-2018 IPR032874 DDE domain CSW12_RS29530 8026465e9e102fedbaf4c277d7c9626f 228 Gene3D G3DSA:3.30.420.10 63 223 1.8E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29530 8026465e9e102fedbaf4c277d7c9626f 228 SUPERFAMILY SSF53098 71 185 2.53E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS17455 a61d6faae986d05b6f0227e74e8bcf20 367 SUPERFAMILY SSF56300 9 200 1.25E-34 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS17455 a61d6faae986d05b6f0227e74e8bcf20 367 Gene3D G3DSA:3.60.21.10 2 251 3.0E-32 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS17455 a61d6faae986d05b6f0227e74e8bcf20 367 Gene3D G3DSA:2.30.30.40 256 366 3.3E-4 T 29-03-2018 CSW12_RS17455 a61d6faae986d05b6f0227e74e8bcf20 367 Pfam PF00149 Calcineurin-like phosphoesterase 14 199 6.4E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS28530 315193ef35895022503176921ab8aa17 254 PIRSF PIRSF005902 1 254 1.3E-61 T 29-03-2018 IPR001130 TatD family GO:0016788 CSW12_RS28530 315193ef35895022503176921ab8aa17 254 SUPERFAMILY SSF51556 3 251 2.48E-55 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS28530 315193ef35895022503176921ab8aa17 254 Gene3D G3DSA:3.20.20.140 1 253 9.2E-62 T 29-03-2018 CSW12_RS28530 315193ef35895022503176921ab8aa17 254 Pfam PF01026 TatD related DNase 4 251 1.6E-50 T 29-03-2018 IPR001130 TatD family GO:0016788 CSW12_RS14040 7f3cbb31763852ac7f792467721d0574 329 SUPERFAMILY SSF55469 239 324 3.85E-19 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS14040 7f3cbb31763852ac7f792467721d0574 329 SUPERFAMILY SSF55469 140 212 3.85E-19 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS14040 7f3cbb31763852ac7f792467721d0574 329 Gene3D G3DSA:3.40.109.10 90 326 1.2E-24 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS14040 7f3cbb31763852ac7f792467721d0574 329 Pfam PF00881 Nitroreductase family 146 319 2.8E-24 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS14040 7f3cbb31763852ac7f792467721d0574 329 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 163 324 3.5E-45 T 29-03-2018 IPR020051 SagB-type dehydrogenase domain CSW12_RS01110 b258b7df4cda70234d2aa261a23675c3 423 SUPERFAMILY SSF56601 113 418 1.1E-79 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS01110 b258b7df4cda70234d2aa261a23675c3 423 Pfam PF00144 Beta-lactamase 125 406 1.6E-55 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS01110 b258b7df4cda70234d2aa261a23675c3 423 Gene3D G3DSA:3.40.710.10 68 421 8.0E-74 T 29-03-2018 CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 SUPERFAMILY SSF46894 128 228 5.67E-30 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-33 T 29-03-2018 CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 SUPERFAMILY SSF52172 3 130 7.12E-40 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 2.4E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 SMART SM00862 151 227 2.0E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 Gene3D G3DSA:1.10.10.10 125 229 8.0E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23000 f369b533542ed8c2eb861bc0b8238557 229 SMART SM00448 2 112 4.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS22190 be5568548a7e67fa0676f83e4a82340c 149 SUPERFAMILY SSF111126 16 128 3.14E-24 T 29-03-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain CSW12_RS22190 be5568548a7e67fa0676f83e4a82340c 149 Pfam PF10702 Protein of unknown function (DUF2507) 18 140 6.1E-49 T 29-03-2018 IPR019642 Protein of unknown function DUF2507 CSW12_RS22190 be5568548a7e67fa0676f83e4a82340c 149 Gene3D G3DSA:3.30.1380.20 2 141 5.9E-23 T 29-03-2018 CSW12_RS30240 c62bba9f07c6ef09e4174f8a9bf2021b 478 Pfam PF01609 Transposase DDE domain 119 385 6.9E-59 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CSW12_RS30240 c62bba9f07c6ef09e4174f8a9bf2021b 478 Gene3D G3DSA:3.90.350.10 183 368 3.7E-24 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CSW12_RS30240 c62bba9f07c6ef09e4174f8a9bf2021b 478 SUPERFAMILY SSF53098 29 475 4.78E-76 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29560 c62bba9f07c6ef09e4174f8a9bf2021b 478 Pfam PF01609 Transposase DDE domain 119 385 6.9E-59 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CSW12_RS29560 c62bba9f07c6ef09e4174f8a9bf2021b 478 Gene3D G3DSA:3.90.350.10 183 368 3.7E-24 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CSW12_RS29560 c62bba9f07c6ef09e4174f8a9bf2021b 478 SUPERFAMILY SSF53098 29 475 4.78E-76 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS24535 7de1a92089542772cc1d234e1722dd3c 225 Pfam PF02517 CAAX protease self-immunity 129 216 2.5E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 Gene3D G3DSA:3.40.50.300 2 368 3.4E-31 T 29-03-2018 CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 348 1.1E-20 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 375 105.132 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 SUPERFAMILY SSF52540 244 352 8.91E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 SUPERFAMILY SSF52540 2 217 8.91E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 29-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CSW12_RS27325 ce35daf5ea34b608bfa1b467d6fbf247 375 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 366 3.0E-132 T 29-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 SUPERFAMILY SSF52172 2 129 6.97E-41 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 1.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 SMART SM00448 3 113 3.5E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 Gene3D G3DSA:1.10.10.10 127 231 1.7E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 SUPERFAMILY SSF46894 128 229 2.38E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 Pfam PF00072 Response regulator receiver domain 5 114 2.2E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 Gene3D G3DSA:3.40.50.2300 1 126 3.8E-36 T 29-03-2018 CSW12_RS14950 fb3d6eee1747ffc8c69e0440399cba63 231 SMART SM00862 153 229 6.7E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS03040 ed5ef4d76b46827a614dfb49189b13b8 384 Pfam PF00582 Universal stress protein family 254 371 1.0E-10 T 29-03-2018 IPR006016 UspA GO:0006950 CSW12_RS03040 ed5ef4d76b46827a614dfb49189b13b8 384 Gene3D G3DSA:3.40.50.300 29 169 8.5E-21 T 29-03-2018 CSW12_RS03040 ed5ef4d76b46827a614dfb49189b13b8 384 SUPERFAMILY SSF52402 254 372 4.74E-15 T 29-03-2018 CSW12_RS03040 ed5ef4d76b46827a614dfb49189b13b8 384 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 30 237 4.7E-88 T 29-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CSW12_RS03040 ed5ef4d76b46827a614dfb49189b13b8 384 Gene3D G3DSA:3.40.50.620 252 383 6.4E-14 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS26785 e8431377b2605e7a13ec19d901575cbe 305 SUPERFAMILY SSF52540 3 225 3.52E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26785 e8431377b2605e7a13ec19d901575cbe 305 SMART SM00382 29 218 2.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26785 e8431377b2605e7a13ec19d901575cbe 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26785 e8431377b2605e7a13ec19d901575cbe 305 Pfam PF00005 ABC transporter 21 161 5.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26785 e8431377b2605e7a13ec19d901575cbe 305 Gene3D G3DSA:3.40.50.300 1 272 5.5E-64 T 29-03-2018 CSW12_RS20900 2b46b81ae790275b59b26c654b5801fd 170 Gene3D G3DSA:3.40.50.850 4 168 3.0E-28 T 29-03-2018 CSW12_RS20900 2b46b81ae790275b59b26c654b5801fd 170 Pfam PF00857 Isochorismatase family 7 143 4.7E-31 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS20900 2b46b81ae790275b59b26c654b5801fd 170 SUPERFAMILY SSF52499 7 165 1.83E-37 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 SMART SM00283 195 428 4.8E-22 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 Pfam PF11563 Protoglobin 32 186 1.0E-37 T 29-03-2018 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 Gene3D G3DSA:1.10.490.10 12 187 7.8E-28 T 29-03-2018 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 SUPERFAMILY SSF58104 144 156 4.32E-50 T 29-03-2018 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 SUPERFAMILY SSF58104 201 426 4.32E-50 T 29-03-2018 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 SUPERFAMILY SSF46458 16 178 4.8E-36 T 29-03-2018 IPR009050 Globin-like CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 Gene3D G3DSA:1.10.287.950 202 421 6.6E-40 T 29-03-2018 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 240 421 4.6E-35 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 209 238 3.1E-5 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS26900 4314ad1fdeea920edfe8c8dc87db39d4 433 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 322 351 3.1E-5 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS28420 feed32ba354e4bc783ae9678a8010156 546 Gene3D G3DSA:3.40.190.10 177 309 1.5E-35 T 29-03-2018 CSW12_RS28420 feed32ba354e4bc783ae9678a8010156 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 463 1.1E-73 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS28420 feed32ba354e4bc783ae9678a8010156 546 SUPERFAMILY SSF53850 36 531 1.16E-119 T 29-03-2018 CSW12_RS28420 feed32ba354e4bc783ae9678a8010156 546 Gene3D G3DSA:3.90.76.10 66 176 5.1E-33 T 29-03-2018 CSW12_RS28420 feed32ba354e4bc783ae9678a8010156 546 Gene3D G3DSA:3.10.105.10 310 516 2.5E-45 T 29-03-2018 CSW12_RS28420 feed32ba354e4bc783ae9678a8010156 546 PIRSF PIRSF002741 2 546 2.4E-104 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 SUPERFAMILY SSF51430 6 274 1.31E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 Gene3D G3DSA:3.20.20.100 1 278 1.1E-100 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PIRSF PIRSF000097 1 124 2.8E-41 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PIRSF PIRSF000097 119 275 3.7E-53 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PRINTS PR00069 Aldo-keto reductase signature 99 117 1.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 1.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 1.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 1.2E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS25130 f49ddc763107a81601a1da15cc1e2246 279 Pfam PF00248 Aldo/keto reductase family 30 265 3.0E-50 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17295 63e89ae9bb0c1fdfee8eea9dc9e4b521 320 PIRSF PIRSF002849 1 315 6.9E-135 T 29-03-2018 CSW12_RS17295 63e89ae9bb0c1fdfee8eea9dc9e4b521 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 9.2E-64 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CSW12_RS17295 63e89ae9bb0c1fdfee8eea9dc9e4b521 320 Gene3D G3DSA:3.40.50.300 12 188 1.5E-23 T 29-03-2018 CSW12_RS17295 63e89ae9bb0c1fdfee8eea9dc9e4b521 320 SUPERFAMILY SSF52540 9 285 4.7E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17295 63e89ae9bb0c1fdfee8eea9dc9e4b521 320 Gene3D G3DSA:1.10.8.300 202 310 1.5E-32 T 29-03-2018 CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 2.6E-264 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 Gene3D G3DSA:3.40.50.880 287 535 1.4E-71 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 Gene3D G3DSA:3.40.50.300 1 286 1.5E-134 T 29-03-2018 CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 SUPERFAMILY SSF52540 1 269 3.0E-127 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 52.985 T 29-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 Pfam PF06418 CTP synthase N-terminus 3 267 8.1E-131 T 29-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 SUPERFAMILY SSF52317 289 533 5.5E-84 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS26485 415e9f77931efdc833f733744debd24e 535 Pfam PF00117 Glutamine amidotransferase class-I 302 526 3.1E-60 T 29-03-2018 IPR017926 Glutamine amidotransferase CSW12_RS03925 f215fde90738e876e517099150906dcc 813 SMART SM00490 461 542 1.1E-10 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS03925 f215fde90738e876e517099150906dcc 813 SUPERFAMILY SSF56024 11 131 5.97E-9 T 29-03-2018 CSW12_RS03925 f215fde90738e876e517099150906dcc 813 Gene3D G3DSA:3.30.870.10 3 192 4.4E-15 T 29-03-2018 CSW12_RS03925 f215fde90738e876e517099150906dcc 813 Pfam PF00271 Helicase conserved C-terminal domain 438 540 7.4E-15 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS03925 f215fde90738e876e517099150906dcc 813 Gene3D G3DSA:3.40.50.300 422 750 9.1E-23 T 29-03-2018 CSW12_RS03925 f215fde90738e876e517099150906dcc 813 SMART SM00487 218 394 2.8E-14 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS03925 f215fde90738e876e517099150906dcc 813 SUPERFAMILY SSF52540 266 407 2.15E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03925 f215fde90738e876e517099150906dcc 813 SUPERFAMILY SSF52540 434 558 2.15E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03925 f215fde90738e876e517099150906dcc 813 Gene3D G3DSA:3.40.50.300 206 382 2.0E-27 T 29-03-2018 CSW12_RS03925 f215fde90738e876e517099150906dcc 813 Pfam PF13091 PLD-like domain 18 145 8.6E-11 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS03925 f215fde90738e876e517099150906dcc 813 Pfam PF04851 Type III restriction enzyme, res subunit 220 367 2.3E-31 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CSW12_RS23755 df76b9b26462aa9d12cf7d820eaa1e71 134 Pfam PF03994 Domain of Unknown Function (DUF350) 12 65 1.0E-5 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 Gene3D G3DSA:3.20.20.120 137 324 5.0E-59 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 Pfam PF13378 Enolase C-terminal domain-like 143 326 1.2E-48 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 SUPERFAMILY SSF51604 127 339 7.86E-64 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 Gene3D G3DSA:3.30.390.10 1 136 2.3E-30 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 4 124 6.2E-18 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 SMART SM00922 140 238 5.8E-26 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CSW12_RS13435 a9dfb7711a6037bb114e90577a291f63 350 SUPERFAMILY SSF54826 1 125 5.07E-29 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS15560 786bca0d51f90dae31555dad7d6a34a3 223 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS15560 786bca0d51f90dae31555dad7d6a34a3 223 SUPERFAMILY SSF51161 31 212 1.66E-43 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS15560 786bca0d51f90dae31555dad7d6a34a3 223 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 8.2E-11 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS15560 786bca0d51f90dae31555dad7d6a34a3 223 Gene3D G3DSA:2.160.10.10 2 218 7.1E-46 T 29-03-2018 CSW12_RS02045 cc2fb48338b9f483e7807a9f1bf8dc8a 386 SUPERFAMILY SSF56349 59 366 4.12E-65 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS02045 cc2fb48338b9f483e7807a9f1bf8dc8a 386 Pfam PF00589 Phage integrase family 175 362 1.8E-28 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS02045 cc2fb48338b9f483e7807a9f1bf8dc8a 386 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 60 118 2.1E-18 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CSW12_RS02045 cc2fb48338b9f483e7807a9f1bf8dc8a 386 Pfam PF14657 Arm DNA-binding domain 10 52 4.0E-12 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain CSW12_RS02045 cc2fb48338b9f483e7807a9f1bf8dc8a 386 Gene3D G3DSA:1.10.443.10 169 364 6.1E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS02045 cc2fb48338b9f483e7807a9f1bf8dc8a 386 Gene3D G3DSA:1.10.150.130 53 168 7.0E-22 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SMART SM01058 499 596 5.8E-50 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SUPERFAMILY SSF52540 543 803 1.46E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SUPERFAMILY SSF52540 802 1008 4.44E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SUPERFAMILY SSF52540 13 366 5.46E-90 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Pfam PF00270 DEAD/DEAH box helicase 625 784 2.1E-17 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Gene3D G3DSA:3.40.50.300 9 442 3.4E-4 T 29-03-2018 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SUPERFAMILY SSF52540 377 490 2.6E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SMART SM00490 846 930 2.7E-19 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Gene3D G3DSA:3.40.50.300 454 791 2.5E-38 T 29-03-2018 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SMART SM00982 1024 1124 3.4E-38 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1147 29.882 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Pfam PF02559 CarD-like/TRCF domain 500 595 7.0E-32 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Pfam PF00271 Helicase conserved C-terminal domain 828 929 2.0E-17 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Pfam PF03461 TRCF domain 1025 1117 5.0E-26 T 29-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SUPERFAMILY SSF143517 1015 1168 1.23E-34 T 29-03-2018 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SMART SM00487 620 810 3.7E-36 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1098 0.0 T 29-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 Gene3D G3DSA:3.40.50.300 811 976 4.5E-26 T 29-03-2018 CSW12_RS27610 871e1aafb46512e0ee5d379b442cc9c8 1176 SUPERFAMILY SSF141259 490 568 1.7E-26 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS29735 7d28b86973730b1f7bbf6972da186cc7 71 Pfam PF01381 Helix-turn-helix 3 57 1.8E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29735 7d28b86973730b1f7bbf6972da186cc7 71 SMART SM00530 2 57 1.1E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29735 7d28b86973730b1f7bbf6972da186cc7 71 SUPERFAMILY SSF47413 2 61 1.27E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS29735 7d28b86973730b1f7bbf6972da186cc7 71 Gene3D G3DSA:1.10.260.40 1 70 5.8E-12 T 29-03-2018 CSW12_RS30500 7d28b86973730b1f7bbf6972da186cc7 71 Pfam PF01381 Helix-turn-helix 3 57 1.8E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30500 7d28b86973730b1f7bbf6972da186cc7 71 SMART SM00530 2 57 1.1E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30500 7d28b86973730b1f7bbf6972da186cc7 71 SUPERFAMILY SSF47413 2 61 1.27E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS30500 7d28b86973730b1f7bbf6972da186cc7 71 Gene3D G3DSA:1.10.260.40 1 70 5.8E-12 T 29-03-2018 CSW12_RS28295 f0a915415eef16af62dadbd1801c6957 655 Gene3D G3DSA:3.40.50.1820 347 653 4.7E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS28295 f0a915415eef16af62dadbd1801c6957 655 Pfam PF00326 Prolyl oligopeptidase family 446 644 5.3E-41 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CSW12_RS28295 f0a915415eef16af62dadbd1801c6957 655 SUPERFAMILY SSF53474 388 643 4.42E-60 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS28295 f0a915415eef16af62dadbd1801c6957 655 Pfam PF07676 WD40-like Beta Propeller Repeat 63 98 0.012 T 29-03-2018 IPR011659 WD40-like Beta Propeller CSW12_RS28295 f0a915415eef16af62dadbd1801c6957 655 SUPERFAMILY SSF82171 20 356 9.81E-33 T 29-03-2018 CSW12_RS28295 f0a915415eef16af62dadbd1801c6957 655 Gene3D G3DSA:2.130.10.150 20 346 4.9E-32 T 29-03-2018 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 5.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 5.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 5.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.3E-33 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 Gene3D G3DSA:4.10.520.10 1 91 4.9E-34 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 SMART SM00411 1 90 1.8E-42 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 SUPERFAMILY SSF47729 1 90 5.89E-32 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS30125 0a424c0e9ca65d16155d952dfd60364e 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CSW12_RS19200 2cabc04177df9be674010e93d361eb15 236 SMART SM00863 189 232 6.2E-14 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS19200 2cabc04177df9be674010e93d361eb15 236 SUPERFAMILY SSF55186 90 234 1.7E-39 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CSW12_RS19200 2cabc04177df9be674010e93d361eb15 236 SUPERFAMILY SSF50447 1 73 7.42E-16 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS19200 2cabc04177df9be674010e93d361eb15 236 Gene3D G3DSA:3.30.980.10 87 235 1.7E-34 T 29-03-2018 CSW12_RS19200 2cabc04177df9be674010e93d361eb15 236 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 189 231 4.5E-13 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS19200 2cabc04177df9be674010e93d361eb15 236 Pfam PF01411 tRNA synthetases class II (A) 13 88 2.7E-12 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 Gene3D G3DSA:3.40.50.200 10 314 6.9E-88 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 255 265 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 52 63 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 PRINTS PR00723 Subtilisin serine protease family (S8) signature 47 66 2.0E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 PRINTS PR00723 Subtilisin serine protease family (S8) signature 89 102 2.0E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 270 2.0E-22 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 SUPERFAMILY SSF52743 29 313 3.93E-84 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 Pfam PF00082 Subtilase family 47 298 4.9E-56 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS17855 f6a8d46d4fe7c35bee5163459a87ebe9 315 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 93 103 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CSW12_RS09555 bb70809ff9b96b63fd4590fb711f2442 123 Gene3D G3DSA:3.10.180.10 9 123 7.7E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09555 bb70809ff9b96b63fd4590fb711f2442 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 118 3.0E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS09555 bb70809ff9b96b63fd4590fb711f2442 123 SUPERFAMILY SSF54593 5 122 1.48E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 2.0E-56 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 SUPERFAMILY SSF55826 218 386 1.7E-33 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 Gene3D G3DSA:3.40.50.800 458 566 3.6E-30 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 562 1.4E-243 T 29-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 PIRSF PIRSF001535 1 566 4.8E-268 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 SUPERFAMILY SSF52954 460 565 7.1E-30 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 Pfam PF04073 Aminoacyl-tRNA editing domain 257 374 4.1E-28 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 3.3E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 3.3E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 3.3E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 3.3E-17 T 29-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 566 41.424 T 29-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 Gene3D G3DSA:3.30.930.10 11 457 1.3E-96 T 29-03-2018 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 SUPERFAMILY SSF55681 9 237 3.11E-103 T 29-03-2018 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 SUPERFAMILY SSF55681 404 475 3.11E-103 T 29-03-2018 CSW12_RS08680 e79050d8952c865dfc8e8bc2afcdfa38 566 Pfam PF03129 Anticodon binding domain 473 563 1.4E-20 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS01075 a288ef7674702f1c41bb34f2da849ea5 217 SUPERFAMILY SSF47413 7 76 6.57E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS01075 a288ef7674702f1c41bb34f2da849ea5 217 Pfam PF01381 Helix-turn-helix 14 68 1.5E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS01075 a288ef7674702f1c41bb34f2da849ea5 217 Pfam PF06803 Protein of unknown function (DUF1232) 170 203 2.5E-11 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CSW12_RS01075 a288ef7674702f1c41bb34f2da849ea5 217 Gene3D G3DSA:1.10.3100.10 3 176 1.3E-16 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS01075 a288ef7674702f1c41bb34f2da849ea5 217 SMART SM00530 13 68 4.1E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 Pfam PF06725 3D domain 249 309 7.8E-20 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 SUPERFAMILY SSF50685 248 299 1.5E-10 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 Gene3D G3DSA:2.40.40.10 150 309 1.2E-42 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 SMART SM00287 85 144 3.6E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 SMART SM00287 23 84 1.6E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 Gene3D G3DSA:2.30.30.410 83 149 5.7E-15 T 29-03-2018 CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 Pfam PF08239 Bacterial SH3 domain 91 138 7.5E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 Pfam PF08239 Bacterial SH3 domain 32 81 5.2E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS09220 a30171e897fc18ec6f28c957f39f12f1 310 Gene3D G3DSA:2.40.50.110 19 82 1.9E-15 T 29-03-2018 CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 Pfam PF07702 UTRA domain 95 234 3.4E-47 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 SUPERFAMILY SSF46785 4 78 2.73E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.1E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 SMART SM00866 95 234 9.8E-51 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.0E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 Gene3D G3DSA:3.40.1410.10 77 243 1.0E-53 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 SUPERFAMILY SSF64288 62 241 3.61E-58 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 Gene3D G3DSA:1.10.10.10 1 76 1.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07420 2c4363d057c9302ff77c906081410954 243 SMART SM00345 15 74 7.6E-24 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 2 248 1.2E-138 T 29-03-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 SUPERFAMILY SSF52540 5 241 1.64E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 SMART SM00382 29 212 5.6E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 SUPERFAMILY SSF50331 245 324 7.37E-6 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 Pfam PF08402 TOBE domain 249 324 2.0E-6 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 Pfam PF00005 ABC transporter 20 162 2.1E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 Gene3D G3DSA:3.40.50.300 1 293 2.1E-80 T 29-03-2018 CSW12_RS06160 be5c1920560a141b6cd65d574b01525f 333 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS13755 d30dfacd48f07eb98f7cc6faf71cd568 170 Pfam PF01230 HIT domain 38 125 7.7E-8 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS13755 d30dfacd48f07eb98f7cc6faf71cd568 170 SUPERFAMILY SSF54197 20 162 3.56E-30 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS13755 d30dfacd48f07eb98f7cc6faf71cd568 170 Gene3D G3DSA:3.30.428.10 11 170 2.3E-27 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 Gene3D G3DSA:3.60.120.10 3 461 1.1E-161 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 SUPERFAMILY SSF56322 9 456 1.09E-149 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 Pfam PF00425 chorismate binding enzyme 197 449 3.4E-100 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 Pfam PF04715 Anthranilate synthase component I, N terminal region 24 148 3.1E-32 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 PRINTS PR00095 Anthranilate synthase component I signature 406 420 2.9E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 PRINTS PR00095 Anthranilate synthase component I signature 311 324 2.9E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 PRINTS PR00095 Anthranilate synthase component I signature 391 405 2.9E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS27700 9b1370ba7c404bfc00a4924d68443081 465 PRINTS PR00095 Anthranilate synthase component I signature 297 310 2.9E-19 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Gene3D G3DSA:1.25.40.10 182 274 3.3E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Gene3D G3DSA:1.20.1250.10 116 181 1.8E-4 T 29-03-2018 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Gene3D G3DSA:1.25.40.10 85 115 6.3E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 SMART SM00028 68 101 7.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 SMART SM00028 165 198 190.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 SMART SM00028 33 67 19.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Pfam PF13181 Tetratricopeptide repeat 102 127 0.18 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 SUPERFAMILY SSF48452 130 217 4.48E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Gene3D G3DSA:1.25.40.10 2 84 1.5E-18 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 SUPERFAMILY SSF48452 4 158 1.37E-23 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Pfam PF07719 Tetratricopeptide repeat 71 101 2.5E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 CSW12_RS11130 6eecbedf95c5428f57e1d2e1029b9430 304 Pfam PF13432 Tetratricopeptide repeat 10 66 8.2E-5 T 29-03-2018 CSW12_RS09520 b7b7612a6707415133c642748775f11b 524 PIRSF PIRSF006429 1 524 6.9E-148 T 29-03-2018 IPR024188 Glutamate synthase large subunit-like protein CSW12_RS09520 b7b7612a6707415133c642748775f11b 524 SUPERFAMILY SSF51395 7 125 1.41E-91 T 29-03-2018 CSW12_RS09520 b7b7612a6707415133c642748775f11b 524 SUPERFAMILY SSF51395 162 517 1.41E-91 T 29-03-2018 CSW12_RS09520 b7b7612a6707415133c642748775f11b 524 Gene3D G3DSA:3.20.20.70 96 514 4.6E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS09520 b7b7612a6707415133c642748775f11b 524 Pfam PF01645 Conserved region in glutamate synthase 139 491 1.3E-77 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 SMART SM00382 56 227 3.6E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 321 3.1E-174 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 ProSitePatterns PS00321 recA signature. 212 220 - T 29-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 92 121 1.2E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 242 271 1.2E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 296 313 1.2E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 209 237 1.2E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 164 193 1.2E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 PRINTS PR00142 RecA protein signature 126 155 1.2E-84 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 Gene3D G3DSA:3.30.250.10 268 324 1.7E-24 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 Pfam PF00154 recA bacterial DNA recombination protein 7 267 7.1E-146 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 SUPERFAMILY SSF52540 3 266 4.24E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 SUPERFAMILY SSF54752 267 325 7.72E-21 T 29-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 Gene3D G3DSA:3.40.50.300 25 267 7.9E-46 T 29-03-2018 CSW12_RS08880 d4a8c22acea0bd6832bd18d60545ebf4 343 Hamap MF_00268 Protein RecA [recA]. 4 328 52.836 T 29-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CSW12_RS13980 ee0fc5bb175ae2d6c5244157f2bd0cb2 389 Gene3D G3DSA:3.30.420.40 5 211 3.3E-24 T 29-03-2018 CSW12_RS13980 ee0fc5bb175ae2d6c5244157f2bd0cb2 389 SUPERFAMILY SSF53067 6 189 8.51E-7 T 29-03-2018 CSW12_RS13980 ee0fc5bb175ae2d6c5244157f2bd0cb2 389 SUPERFAMILY SSF53067 213 367 4.53E-12 T 29-03-2018 CSW12_RS02200 52137f0ce04e0706a5a106bd470133d6 198 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 6 191 4.9E-36 T 29-03-2018 IPR006490 Phage major tail protein, phi13 family CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00668 Condensation domain 10 444 6.8E-70 T 29-03-2018 IPR001242 Condensation domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00668 Condensation domain 1054 1503 3.7E-97 T 29-03-2018 IPR001242 Condensation domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF47336 967 1037 6.15E-18 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF52777 1244 1497 5.34E-59 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF53474 2113 2376 8.11E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF56801 1484 2058 8.37E-169 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SMART SM00823 Phosphopantetheine attachment site 2045 2114 1.4E-5 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SMART SM00823 Phosphopantetheine attachment site 972 1041 0.0011 T 29-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00975 Thioesterase domain 2133 2289 1.0E-30 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00550 Phosphopantetheine attachment site 975 1036 6.7E-13 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00550 Phosphopantetheine attachment site 2048 2110 1.7E-14 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.30.300.30 859 977 3.0E-38 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.30.300.30 1932 2050 8.1E-40 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF47336 2040 2110 2.09E-20 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00501 AMP-binding enzyme 465 864 3.5E-107 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF00501 AMP-binding enzyme 1525 1937 1.6E-108 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF56801 431 985 1.7E-157 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SMART SM00824 Thioesterase 2135 2293 6.3E-4 T 29-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF52777 11 184 3.34E-31 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:2.30.38.10 773 854 1.1E-24 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.40.50.980 1518 1676 2.2E-49 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.40.50.980 459 617 8.3E-45 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.30.559.10 1039 1260 2.5E-39 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF52777 190 427 4.89E-34 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1672 1683 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.30.559.10 2 193 9.4E-17 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:1.10.1200.10 978 1038 6.2E-21 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:1.10.1200.10 2051 2115 1.4E-23 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 SUPERFAMILY SSF52777 1058 1230 3.34E-43 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 888 5.4E-136 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1546 1961 4.6E-140 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.40.50.1820 2116 2377 1.1E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:2.30.38.10 1849 1930 1.6E-23 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF13193 AMP-binding enzyme C-terminal domain 1945 2020 8.3E-14 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Pfam PF13193 AMP-binding enzyme C-terminal domain 872 947 6.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.40.50.980 618 772 3.3E-35 T 29-03-2018 CSW12_RS16170 b3b04067804e24a325d38d2bbfaf36e4 2385 Gene3D G3DSA:3.40.50.980 1677 1843 9.9E-41 T 29-03-2018 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 Gene3D G3DSA:3.40.50.10860 11 139 4.2E-50 T 29-03-2018 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 SUPERFAMILY SSF53223 1 121 1.06E-40 T 29-03-2018 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 Gene3D G3DSA:3.40.50.720 140 263 6.0E-41 T 29-03-2018 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 SUPERFAMILY SSF51735 122 279 1.63E-54 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.043 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 29-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.9E-84 T 29-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.3E-42 T 29-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS20490 4641a267db7ab3fc4b0518fd863be48b 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 1.1E-72 T 29-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 ProSitePatterns PS00534 Ferrochelatase signature. 176 194 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 Hamap MF_00323 Ferrochelatase [hemH]. 4 306 31.554 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 Gene3D G3DSA:3.40.50.1400 2 162 7.2E-26 T 29-03-2018 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 Gene3D G3DSA:3.40.50.1400 163 287 8.7E-39 T 29-03-2018 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 TIGRFAM TIGR00109 hemH: ferrochelatase 2 305 7.4E-90 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 Pfam PF00762 Ferrochelatase 5 305 7.1E-82 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS05275 10b778500f5e741ca6584d3e0010474c 319 SUPERFAMILY SSF53800 3 305 6.21E-89 T 29-03-2018 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 Gene3D G3DSA:3.40.640.10 147 359 7.9E-37 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 SMART SM00345 20 79 5.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 Pfam PF00155 Aminotransferase class I and II 122 473 1.9E-32 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 1.2E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 7.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 7.2E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 Gene3D G3DSA:1.10.10.10 8 81 1.8E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 SUPERFAMILY SSF46785 13 83 8.19E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 SUPERFAMILY SSF53383 111 479 2.23E-89 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS17910 bda703029aec1e2b0cd1e835b473c706 480 Gene3D G3DSA:3.90.1150.10 360 480 2.8E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 3 372 62.521 T 29-03-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 SUPERFAMILY SSF53187 290 369 5.11E-66 T 29-03-2018 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 SUPERFAMILY SSF53187 4 189 5.11E-66 T 29-03-2018 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 361 2.2E-88 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 SUPERFAMILY SSF55031 178 283 4.97E-28 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 Pfam PF07687 Peptidase dimerisation domain 180 269 9.5E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 Pfam PF01546 Peptidase family M20/M25/M40 67 370 2.5E-25 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 Gene3D G3DSA:3.40.630.10 3 208 9.8E-34 T 29-03-2018 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 Gene3D G3DSA:3.40.630.10 234 370 2.9E-16 T 29-03-2018 CSW12_RS07835 594fb8203a1b48daa9fde66d8b954923 376 PIRSF PIRSF005962 1 376 1.2E-104 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS18465 5f372556fba578efdc348524d9100eba 319 Pfam PF00581 Rhodanese-like domain 118 212 4.7E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS18465 5f372556fba578efdc348524d9100eba 319 Hamap MF_00469 UPF0176 protein YceA [yceA]. 5 269 39.316 T 29-03-2018 IPR020936 Uncharacterised protein family UPF0176 CSW12_RS18465 5f372556fba578efdc348524d9100eba 319 Gene3D G3DSA:3.40.250.10 111 222 3.9E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS18465 5f372556fba578efdc348524d9100eba 319 SUPERFAMILY SSF52821 90 248 4.12E-36 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS18465 5f372556fba578efdc348524d9100eba 319 Pfam PF12368 Rhodanase C-terminal 224 290 1.6E-14 T 29-03-2018 IPR022111 Rhodanase, C-terminal CSW12_RS18465 5f372556fba578efdc348524d9100eba 319 SMART SM00450 117 218 1.6E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS12400 94262843cccf6d1adbc431616038fd81 132 Pfam PF01521 Iron-sulphur cluster biosynthesis 32 124 3.1E-7 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS12400 94262843cccf6d1adbc431616038fd81 132 Gene3D G3DSA:2.60.300.12 32 132 1.9E-15 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS12400 94262843cccf6d1adbc431616038fd81 132 SUPERFAMILY SSF89360 32 120 8.11E-5 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS09435 db8c00ae65d719d6c8ebc1fa81fce422 302 Pfam PF00892 EamA-like transporter family 148 279 1.2E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS09435 db8c00ae65d719d6c8ebc1fa81fce422 302 Pfam PF00892 EamA-like transporter family 5 135 6.6E-9 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS09435 db8c00ae65d719d6c8ebc1fa81fce422 302 SUPERFAMILY SSF103481 191 280 2.48E-8 T 29-03-2018 CSW12_RS25125 5b4be2f863560ca50a006f7aedaf6394 304 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 87 123 1.9E-11 T 29-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA CSW12_RS13060 82a0eb3ec715f72156f7d5c38197e078 170 Gene3D G3DSA:2.40.380.10 11 168 2.2E-19 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS13060 82a0eb3ec715f72156f7d5c38197e078 170 SUPERFAMILY SSF159234 23 163 1.29E-28 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS13060 82a0eb3ec715f72156f7d5c38197e078 170 Pfam PF04167 Protein of unknown function (DUF402) 64 129 1.3E-13 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:2.30.330.10 462 545 4.0E-16 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 SUPERFAMILY SSF101801 473 543 2.09E-15 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 26 60 3.0E-11 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 244 279 9.3E-11 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 342 377 8.3E-13 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF04509 CheC-like family 122 158 5.2E-15 T 29-03-2018 IPR007597 CheC-like protein GO:0016787 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 476 543 4.7E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 492 508 1.2E-7 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 521 536 1.2E-7 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 508 521 1.2E-7 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 PRINTS PR00956 Flagellar motor switch protein FliN signature 475 491 1.2E-7 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:3.40.1550.10 196 286 2.5E-18 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:3.40.1550.10 6 69 8.2E-14 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:3.40.1550.10 287 416 7.3E-31 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 Gene3D G3DSA:3.40.1550.10 70 195 1.3E-29 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 SUPERFAMILY SSF103039 20 211 4.19E-45 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS19420 f233f1ab9c841448b8d01403b2e4f795 545 SUPERFAMILY SSF103039 239 430 1.24E-45 T 29-03-2018 IPR028976 CheC-like domain CSW12_RS17350 e04e306192be16fcbf6e91bb4e28f696 127 SUPERFAMILY SSF54593 1 125 1.01E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS17350 e04e306192be16fcbf6e91bb4e28f696 127 Gene3D G3DSA:3.10.180.10 1 127 6.6E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS17350 e04e306192be16fcbf6e91bb4e28f696 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 120 1.3E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS14130 cdeaea1aa034d8af3e08e8966127c95d 146 SUPERFAMILY SSF55811 3 144 2.44E-16 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS14130 cdeaea1aa034d8af3e08e8966127c95d 146 Gene3D G3DSA:3.90.79.10 5 146 2.0E-13 T 29-03-2018 CSW12_RS14130 cdeaea1aa034d8af3e08e8966127c95d 146 Pfam PF00293 NUDIX domain 27 128 5.0E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS00795 2339ea4825b580278d2f0f1c704bd1aa 106 Pfam PF01910 Thiamine-binding protein 7 96 9.9E-30 T 29-03-2018 IPR002767 Thiamine-binding protein CSW12_RS00795 2339ea4825b580278d2f0f1c704bd1aa 106 Gene3D G3DSA:3.30.70.930 1 104 6.3E-30 T 29-03-2018 IPR029756 MTH1187/YkoF-like CSW12_RS00795 2339ea4825b580278d2f0f1c704bd1aa 106 SUPERFAMILY SSF89957 3 104 1.83E-31 T 29-03-2018 IPR029756 MTH1187/YkoF-like CSW12_RS00795 2339ea4825b580278d2f0f1c704bd1aa 106 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 7 93 3.1E-16 T 29-03-2018 IPR002767 Thiamine-binding protein CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 Pfam PF01274 Malate synthase 10 527 4.7E-216 T 29-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 21 529 7.7E-253 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 SUPERFAMILY SSF51645 6 528 2.62E-198 T 29-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 29-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 Gene3D G3DSA:1.20.1220.12 411 529 1.1E-45 T 29-03-2018 CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 Gene3D G3DSA:3.20.20.360 76 410 1.8E-120 T 29-03-2018 CSW12_RS04905 02dacd94c80c95c219380ea7d0c16e72 529 PIRSF PIRSF001363 1 529 4.1E-264 T 29-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CSW12_RS21815 7b7e86272bbe407c927c3f26786960c3 640 PIRSF PIRSF018968 1 640 3.6E-127 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS21815 7b7e86272bbe407c927c3f26786960c3 640 Pfam PF02687 FtsX-like permease family 86 180 9.4E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS07775 318ead2b2327624df247545123df9d0d 285 SUPERFAMILY SSF56300 56 282 2.78E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS07775 318ead2b2327624df247545123df9d0d 285 Gene3D G3DSA:3.60.21.10 55 285 5.2E-27 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS07775 318ead2b2327624df247545123df9d0d 285 Pfam PF00149 Calcineurin-like phosphoesterase 58 223 9.2E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS17030 a479c69bd970a8981baee74942de5356 254 SUPERFAMILY SSF53300 13 176 3.41E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS17030 a479c69bd970a8981baee74942de5356 254 Gene3D G3DSA:3.40.50.410 4 250 1.9E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS17030 a479c69bd970a8981baee74942de5356 254 SMART SM00327 12 208 4.7E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS17030 a479c69bd970a8981baee74942de5356 254 Pfam PF13519 von Willebrand factor type A domain 16 140 1.5E-7 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 Pfam PF00107 Zinc-binding dehydrogenase 164 277 6.8E-17 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 7 331 7.1E-141 T 29-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 Gene3D G3DSA:3.40.50.720 167 276 1.1E-12 T 29-03-2018 CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 SUPERFAMILY SSF51735 121 294 6.71E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 92 3.3E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 Gene3D G3DSA:3.90.180.10 1 166 6.0E-37 T 29-03-2018 CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 SUPERFAMILY SSF50129 6 150 3.65E-42 T 29-03-2018 IPR011032 GroES-like CSW12_RS03265 7eff7dbce03e7e1bc82ef90c2ac95207 331 SMART SM00829 12 329 1.2E-7 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 7.6E-148 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 SUPERFAMILY SSF53901 269 389 5.35E-41 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 SUPERFAMILY SSF53901 3 268 7.29E-85 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 PIRSF PIRSF000429 1 391 3.5E-132 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 7.2E-47 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 Gene3D G3DSA:3.40.47.10 264 388 4.9E-30 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 Gene3D G3DSA:3.40.47.10 1 263 3.8E-64 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS07575 6e7c7968d3e97754a6bdf4d7c65e6987 391 Pfam PF00108 Thiolase, N-terminal domain 4 261 1.1E-89 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CSW12_RS15025 9a30dd7f63e92e43965807dda7f14b63 71 Gene3D G3DSA:2.40.50.100 2 71 2.5E-19 T 29-03-2018 CSW12_RS15025 9a30dd7f63e92e43965807dda7f14b63 71 Pfam PF00364 Biotin-requiring enzyme 9 70 5.2E-17 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS15025 9a30dd7f63e92e43965807dda7f14b63 71 SUPERFAMILY SSF51230 3 71 7.46E-22 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Gene3D G3DSA:3.30.390.30 329 456 9.8E-30 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 SUPERFAMILY SSF52821 437 544 8.38E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Gene3D G3DSA:3.40.250.10 457 554 4.4E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 SUPERFAMILY SSF55424 326 448 2.06E-34 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 307 5.4E-59 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Gene3D G3DSA:3.50.50.60 1 136 3.1E-17 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Gene3D G3DSA:3.40.50.720 137 302 9.4E-38 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 SMART SM00450 454 550 3.0E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 8.8E-23 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 8.8E-23 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 8.8E-23 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 8.8E-23 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.8E-23 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 4 443 2.0E-195 T 29-03-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 1.8E-14 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.8E-14 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 1.8E-14 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.8E-14 T 29-03-2018 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Pfam PF00581 Rhodanese-like domain 467 544 1.6E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 SUPERFAMILY SSF51905 2 319 2.59E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS03210 aee3f1bb702aabbf7d7f374b4938ab69 554 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 434 5.0E-16 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 Gene3D G3DSA:3.40.190.10 1 104 1.2E-41 T 29-03-2018 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 6.1E-79 T 29-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 SUPERFAMILY SSF54782 219 304 3.4E-22 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 38.844 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 SUPERFAMILY SSF53850 2 218 8.54E-82 T 29-03-2018 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 Gene3D G3DSA:3.40.190.10 105 198 9.8E-37 T 29-03-2018 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 7.3E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 7.3E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 7.3E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 7.3E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 7.3E-49 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 2.0E-111 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 5.7E-18 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 29-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 PIRSF PIRSF001438 1 309 2.3E-121 T 29-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21955 37af911ae0c874a089dcbf866a2f1aaa 309 Gene3D G3DSA:3.30.160.40 221 302 1.4E-20 T 29-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SUPERFAMILY SSF47384 358 423 7.26E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SMART SM00388 362 425 6.9E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SMART SM00387 467 574 1.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Pfam PF08448 PAS fold 245 348 1.6E-17 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 519 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 533 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 558 571 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 552 1.1E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SMART SM00091 239 305 0.11 T 29-03-2018 IPR000014 PAS domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SMART SM00091 113 182 7.5E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Gene3D G3DSA:3.30.450.20 96 230 7.3E-17 T 29-03-2018 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Gene3D G3DSA:1.10.287.130 350 421 8.4E-14 T 29-03-2018 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SUPERFAMILY SSF55785 224 345 9.08E-15 T 29-03-2018 IPR000014 PAS domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Gene3D G3DSA:3.30.565.10 425 583 1.4E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Pfam PF00989 PAS fold 113 197 5.0E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Gene3D G3DSA:3.30.450.20 231 349 2.2E-19 T 29-03-2018 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SUPERFAMILY SSF55785 108 225 4.01E-14 T 29-03-2018 IPR000014 PAS domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Pfam PF00512 His Kinase A (phospho-acceptor) domain 364 423 1.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 110 234 1.3E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 SUPERFAMILY SSF55874 416 573 1.3E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14565 e976b95c5f7fa0bf952b879df3934200 595 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 469 572 8.1E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS29575 251fc214bc1cbe665a63e0f2ad970eba 268 Gene3D G3DSA:3.30.420.10 74 236 6.9E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29575 251fc214bc1cbe665a63e0f2ad970eba 268 Pfam PF00665 Integrase core domain 78 186 1.3E-24 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CSW12_RS29575 251fc214bc1cbe665a63e0f2ad970eba 268 SUPERFAMILY SSF53098 76 220 1.39E-30 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS09580 bf42627306e438bb6dcb4980024c24b5 70 SUPERFAMILY SSF69047 9 63 8.37E-13 T 29-03-2018 IPR008462 CsbD-like domain CSW12_RS09580 bf42627306e438bb6dcb4980024c24b5 70 Gene3D G3DSA:1.10.1470.10 8 70 2.1E-15 T 29-03-2018 IPR008462 CsbD-like domain CSW12_RS09580 bf42627306e438bb6dcb4980024c24b5 70 Pfam PF05532 CsbD-like 10 61 1.2E-18 T 29-03-2018 IPR008462 CsbD-like domain CSW12_RS27425 5953c1f7d692ba28d0bd4fff705348f3 166 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CSW12_RS27425 5953c1f7d692ba28d0bd4fff705348f3 166 Gene3D G3DSA:3.40.140.10 1 159 9.9E-52 T 29-03-2018 CSW12_RS27425 5953c1f7d692ba28d0bd4fff705348f3 166 SUPERFAMILY SSF53927 3 155 5.02E-56 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS27425 5953c1f7d692ba28d0bd4fff705348f3 166 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 151 46.993 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CSW12_RS27425 5953c1f7d692ba28d0bd4fff705348f3 166 Pfam PF14437 MafB19-like deaminase 5 151 6.8E-43 T 29-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.1E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 Pfam PF01022 Bacterial regulatory protein, arsR family 19 62 2.5E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 SMART SM00418 11 89 1.1E-24 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 Gene3D G3DSA:1.10.10.10 1 105 4.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10955 ec8739755b9b59c0ccb0e5305d0b46aa 117 SUPERFAMILY SSF46785 3 87 8.37E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01795 8a289cb5f4465a948ffc2b6d07f1fb44 352 Pfam PF01032 FecCD transport family 33 348 2.3E-93 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS01795 8a289cb5f4465a948ffc2b6d07f1fb44 352 SUPERFAMILY SSF81345 14 348 4.45E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS01795 8a289cb5f4465a948ffc2b6d07f1fb44 352 Gene3D G3DSA:1.10.3470.10 17 352 3.3E-69 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 Gene3D G3DSA:2.40.50.140 290 337 7.7E-9 T 29-03-2018 CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 Gene3D G3DSA:3.40.50.300 1 244 1.4E-77 T 29-03-2018 CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 SUPERFAMILY SSF52540 1 241 7.91E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 SUPERFAMILY SSF50331 236 352 1.53E-22 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 Pfam PF00005 ABC transporter 20 161 1.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 Gene3D G3DSA:2.40.50.100 245 289 1.4E-5 T 29-03-2018 CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS01545 e202645987d1349b72ec0368b7df485b 365 SMART SM00382 28 211 3.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 SUPERFAMILY SSF51735 4 246 2.21E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.6E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-41 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 Gene3D G3DSA:3.40.50.720 1 40 6.9E-10 T 29-03-2018 CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 Gene3D G3DSA:3.40.50.720 41 247 3.6E-59 T 29-03-2018 CSW12_RS10605 80a99e756e7a691641bd216d18b12d7b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 1.2E-67 T 29-03-2018 CSW12_RS02785 bedd935f1398ab8e0babbad1184d3676 297 Gene3D G3DSA:1.10.3720.10 19 297 4.6E-37 T 29-03-2018 CSW12_RS02785 bedd935f1398ab8e0babbad1184d3676 297 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 15 294 8.5E-86 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CSW12_RS02785 bedd935f1398ab8e0babbad1184d3676 297 SUPERFAMILY SSF161098 30 288 1.96E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS02785 bedd935f1398ab8e0babbad1184d3676 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 294 9.9E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 Pfam PF08402 TOBE domain 248 325 2.3E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 Gene3D G3DSA:3.40.50.300 1 247 7.9E-76 T 29-03-2018 CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 SUPERFAMILY SSF50331 239 326 4.19E-7 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 SUPERFAMILY SSF52540 4 240 5.32E-87 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 SMART SM00382 29 212 8.9E-20 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 Pfam PF00005 ABC transporter 23 162 7.4E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS05970 b1fd99418dec79fbaa86701af5074ef5 327 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 SUPERFAMILY SSF90123 5 44 2.22E-72 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 SUPERFAMILY SSF90123 138 414 2.22E-72 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 Gene3D G3DSA:1.20.1560.10 2 411 6.9E-66 T 29-03-2018 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 Pfam PF00664 ABC transporter transmembrane region 149 384 6.8E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 Gene3D G3DSA:3.40.50.300 412 665 1.8E-70 T 29-03-2018 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 Pfam PF00005 ABC transporter 444 589 9.7E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 SUPERFAMILY SSF52540 421 660 6.2E-80 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03605 1d89da05df26e8dffa7e74054e1980af 666 SMART SM00382 453 641 1.4E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS17405 ade5f39b44ad9ec306a89c8de0708686 261 Gene3D G3DSA:3.40.630.30 118 261 2.0E-22 T 29-03-2018 CSW12_RS17405 ade5f39b44ad9ec306a89c8de0708686 261 Pfam PF00583 Acetyltransferase (GNAT) family 144 251 1.2E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17405 ade5f39b44ad9ec306a89c8de0708686 261 SUPERFAMILY SSF55729 2 260 1.86E-23 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17405 ade5f39b44ad9ec306a89c8de0708686 261 Gene3D G3DSA:3.40.630.30 1 62 0.15 T 29-03-2018 CSW12_RS09525 422a590e485a7bcc16758c8d84bb1683 162 Pfam PF07301 Protein of unknown function (DUF1453) 6 150 6.4E-44 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CSW12_RS09525 422a590e485a7bcc16758c8d84bb1683 162 PIRSF PIRSF021441 1 161 2.1E-55 T 29-03-2018 IPR031306 CcdC protein CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 638 0.0 T 29-03-2018 IPR011927 Stage V sporulation protein D CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 5.4E-88 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 SUPERFAMILY SSF56519 51 220 1.16E-43 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 Pfam PF03793 PASTA domain 584 637 1.4E-11 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 202 1.9E-22 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 SUPERFAMILY SSF56601 235 567 1.22E-97 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 Gene3D G3DSA:3.90.1310.10 24 217 1.2E-43 T 29-03-2018 CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 SMART SM00740 580 638 2.9E-14 T 29-03-2018 IPR005543 PASTA domain CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 SUPERFAMILY SSF54184 584 637 2.49E-11 T 29-03-2018 CSW12_RS08180 d495bf99086cda51b393d133bbf5fbc2 638 Gene3D G3DSA:3.40.710.10 218 562 2.3E-93 T 29-03-2018 CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 2.5E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 SUPERFAMILY SSF46894 127 223 2.32E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 SMART SM00448 2 112 8.9E-21 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 Gene3D G3DSA:1.10.10.10 122 225 1.5E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 Pfam PF00072 Response regulator receiver domain 4 113 3.4E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 Gene3D G3DSA:3.40.50.2300 2 121 3.4E-23 T 29-03-2018 CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 SUPERFAMILY SSF52172 3 131 8.4E-27 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS25295 1552b5fd90d0f4210f686cd2bdfd3881 225 SMART SM00862 148 223 1.5E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS00280 b78bab1bc3734d55c2c454f50ac7114a 574 Pfam PF03354 Phage Terminase 79 553 5.8E-67 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CSW12_RS17160 97871d23fa75da6293174c5bfeab0e87 91 Pfam PF04232 Stage V sporulation protein S (SpoVS) 4 84 2.3E-39 T 29-03-2018 IPR007347 Sporulation stage V, protein S CSW12_RS17160 97871d23fa75da6293174c5bfeab0e87 91 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 4 87 4.0E-28 T 29-03-2018 IPR007347 Sporulation stage V, protein S CSW12_RS21495 9c9106e4ed063be9f2986908a23bc294 377 Gene3D G3DSA:3.40.640.10 1 244 6.4E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS21495 9c9106e4ed063be9f2986908a23bc294 377 PIRSF PIRSF001434 1 377 2.7E-149 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS21495 9c9106e4ed063be9f2986908a23bc294 377 SUPERFAMILY SSF53383 16 376 1.5E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS21495 9c9106e4ed063be9f2986908a23bc294 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 376 1.1E-158 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS21495 9c9106e4ed063be9f2986908a23bc294 377 Gene3D G3DSA:3.90.1150.10 247 377 2.2E-51 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS21495 9c9106e4ed063be9f2986908a23bc294 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS05510 3b86126cc702190ab687790e7dbb3d5a 608 Pfam PF08439 Oligopeptidase F 120 189 2.4E-26 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CSW12_RS05510 3b86126cc702190ab687790e7dbb3d5a 608 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 13 602 4.0E-224 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CSW12_RS05510 3b86126cc702190ab687790e7dbb3d5a 608 Pfam PF01432 Peptidase family M3 211 591 1.1E-83 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CSW12_RS05510 3b86126cc702190ab687790e7dbb3d5a 608 SUPERFAMILY SSF55486 10 587 5.29E-142 T 29-03-2018 CSW12_RS05510 3b86126cc702190ab687790e7dbb3d5a 608 Gene3D G3DSA:1.10.1370.10 90 603 4.8E-52 T 29-03-2018 CSW12_RS15875 938efaa10d7bcba71efd956c02f5f631 198 PIRSF PIRSF022704 2 198 6.3E-72 T 29-03-2018 IPR015987 Uncharacterised conserved protein UCP022704 CSW12_RS15875 938efaa10d7bcba71efd956c02f5f631 198 SUPERFAMILY SSF49899 35 197 3.8E-29 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CSW12_RS15875 938efaa10d7bcba71efd956c02f5f631 198 Gene3D G3DSA:2.60.120.200 11 198 4.8E-31 T 29-03-2018 CSW12_RS15875 938efaa10d7bcba71efd956c02f5f631 198 Pfam PF07081 Protein of unknown function (DUF1349) 16 197 1.4E-55 T 29-03-2018 IPR009784 Protein of unknown function DUF1349 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 Pfam PF02796 Helix-turn-helix domain of resolvase 140 183 1.6E-13 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 ProSitePatterns PS00398 Site-specific recombinases signature 2. 55 67 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 Gene3D G3DSA:1.20.5.40 107 133 4.8E-17 T 29-03-2018 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 SUPERFAMILY SSF46689 140 181 7.26E-9 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 Gene3D G3DSA:3.40.50.1390 2 106 3.6E-33 T 29-03-2018 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 Pfam PF00239 Resolvase, N terminal domain 3 137 2.2E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 SUPERFAMILY SSF53041 2 137 1.7E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 SMART SM00857 2 138 3.6E-59 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30055 7f1912de2c62160cd220135b229e2e95 183 Gene3D G3DSA:1.10.10.60 134 183 1.5E-11 T 29-03-2018 CSW12_RS24725 9660e2ad2c4f695cbbf365daf608db42 268 Pfam PF03180 NLPA lipoprotein 28 266 6.9E-89 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS24725 9660e2ad2c4f695cbbf365daf608db42 268 SUPERFAMILY SSF53850 27 266 1.56E-80 T 29-03-2018 CSW12_RS24725 9660e2ad2c4f695cbbf365daf608db42 268 Gene3D G3DSA:3.40.190.10 119 266 4.5E-47 T 29-03-2018 CSW12_RS24725 9660e2ad2c4f695cbbf365daf608db42 268 Gene3D G3DSA:3.40.190.10 27 118 6.6E-28 T 29-03-2018 CSW12_RS24725 9660e2ad2c4f695cbbf365daf608db42 268 PIRSF PIRSF002854 1 267 1.1E-99 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS09235 514fd08f25f532e1341c6d422a009697 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 31.451 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS09235 514fd08f25f532e1341c6d422a009697 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 2.7E-32 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS09235 514fd08f25f532e1341c6d422a009697 74 Pfam PF17209 Hfq protein 7 69 5.4E-33 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS09235 514fd08f25f532e1341c6d422a009697 74 Gene3D G3DSA:2.30.30.100 5 69 4.1E-33 T 29-03-2018 CSW12_RS09235 514fd08f25f532e1341c6d422a009697 74 SUPERFAMILY SSF50182 6 65 2.25E-24 T 29-03-2018 IPR010920 LSM domain CSW12_RS19265 f67e2db00722a065c873739edfea718f 261 SUPERFAMILY SSF53955 137 256 1.49E-39 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS19265 f67e2db00722a065c873739edfea718f 261 Gene3D G3DSA:1.10.530.10 25 259 7.2E-46 T 29-03-2018 CSW12_RS19265 f67e2db00722a065c873739edfea718f 261 Pfam PF01464 Transglycosylase SLT domain 145 246 1.0E-24 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 Gene3D G3DSA:3.40.630.10 260 389 5.8E-23 T 29-03-2018 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 SUPERFAMILY SSF53187 12 197 1.04E-77 T 29-03-2018 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 SUPERFAMILY SSF53187 298 388 1.04E-77 T 29-03-2018 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 SUPERFAMILY SSF55031 181 298 6.02E-29 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 374 4.1E-111 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 Gene3D G3DSA:3.40.630.10 8 259 1.8E-42 T 29-03-2018 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 PIRSF PIRSF005962 6 389 9.3E-127 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 Pfam PF01546 Peptidase family M20/M25/M40 72 381 3.6E-32 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS06420 c0575b477573acae5b89bbbf852e14c7 389 Pfam PF07687 Peptidase dimerisation domain 186 278 2.2E-11 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 324 2.2E-118 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 Gene3D G3DSA:3.40.50.620 1 187 2.8E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 Gene3D G3DSA:1.10.240.10 188 307 3.6E-37 T 29-03-2018 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 Pfam PF00579 tRNA synthetases class I (W and Y) 3 278 2.4E-84 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 42.873 T 29-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 SUPERFAMILY SSF52374 3 324 3.16E-100 T 29-03-2018 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 2.1E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 2.1E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 2.1E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS05425 459a14308b7dc572e0457860e88029c5 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 2.1E-29 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 3.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 Pfam PF16925 Bacterial transcriptional repressor C-terminal 83 193 1.9E-8 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.0E-9 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 Gene3D G3DSA:1.10.10.60 7 60 1.1E-14 T 29-03-2018 CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 Gene3D G3DSA:1.10.357.10 61 194 2.8E-11 T 29-03-2018 CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 SUPERFAMILY SSF48498 82 194 8.01E-15 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS11960 84d7149f53c3aeb522da3632141c8422 194 SUPERFAMILY SSF46689 8 75 5.64E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS29145 8750648ed27eedcc415c8597eabed3f9 70 SUPERFAMILY SSF53098 1 65 1.25E-12 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29145 8750648ed27eedcc415c8597eabed3f9 70 Gene3D G3DSA:3.30.420.10 1 70 2.3E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29145 8750648ed27eedcc415c8597eabed3f9 70 Pfam PF13683 Integrase core domain 1 62 4.2E-16 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CSW12_RS29675 8750648ed27eedcc415c8597eabed3f9 70 SUPERFAMILY SSF53098 1 65 1.25E-12 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29675 8750648ed27eedcc415c8597eabed3f9 70 Gene3D G3DSA:3.30.420.10 1 70 2.3E-14 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29675 8750648ed27eedcc415c8597eabed3f9 70 Pfam PF13683 Integrase core domain 1 62 4.2E-16 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 SUPERFAMILY SSF53335 75 458 6.46E-83 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 95 458 9.1E-19 T 29-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 Gene3D G3DSA:3.40.50.150 164 457 1.5E-49 T 29-03-2018 CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 Gene3D G3DSA:3.40.50.150 82 149 8.0E-12 T 29-03-2018 CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 441 451 - T 29-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 Gene3D G3DSA:2.40.50.140 1 81 9.7E-24 T 29-03-2018 CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 Pfam PF01938 TRAM domain 10 65 1.2E-12 T 29-03-2018 IPR002792 TRAM domain CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 SUPERFAMILY SSF50249 3 66 4.85E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 390 421 - T 29-03-2018 IPR030390 RNA methyltransferase TrmA, active site CSW12_RS01035 f7105e352bfcbd769b2e246cd074c40f 459 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 451 4.5E-176 T 29-03-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 Gene3D G3DSA:3.40.50.980 163 311 1.9E-37 T 29-03-2018 CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 Gene3D G3DSA:3.30.300.30 394 495 3.0E-23 T 29-03-2018 CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 SUPERFAMILY SSF56801 3 494 2.09E-134 T 29-03-2018 CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 484 3.3E-15 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 Gene3D G3DSA:3.40.50.980 1 162 5.3E-37 T 29-03-2018 CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 Gene3D G3DSA:2.30.38.10 312 393 3.5E-25 T 29-03-2018 CSW12_RS10820 70f30e3f497e50035b3796b89bb24d71 497 Pfam PF00501 AMP-binding enzyme 6 401 1.3E-95 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 SUPERFAMILY SSF90123 14 313 1.15E-63 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 SUPERFAMILY SSF52540 324 565 1.49E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 Gene3D G3DSA:3.40.50.300 328 564 1.7E-69 T 29-03-2018 CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 Gene3D G3DSA:1.20.1560.10 5 323 2.0E-59 T 29-03-2018 CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 Pfam PF00005 ABC transporter 346 497 3.1E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 SMART SM00382 355 550 3.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS27065 95e7a1a16f3c2d60e5ccd9ccf66767d4 568 Pfam PF00664 ABC transporter transmembrane region 22 288 1.4E-40 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:3.50.30.10 136 255 1.6E-32 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 185 196 - T 29-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:1.10.274.10 26 135 2.6E-38 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF52009 126 247 3.66E-38 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 294 313 2.7E-32 T 29-03-2018 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 449 464 2.7E-32 T 29-03-2018 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 2.7E-32 T 29-03-2018 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 2.7E-32 T 29-03-2018 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF51621 251 551 1.73E-111 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 226 9.6E-24 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 Gene3D G3DSA:3.20.20.60 256 570 1.1E-102 T 29-03-2018 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 127 8.5E-34 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 568 1.7E-255 T 29-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 PIRSF PIRSF000732 1 570 2.2E-226 T 29-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 SUPERFAMILY SSF47831 25 144 1.12E-37 T 29-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 449 467 - T 29-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CSW12_RS07445 7f3ab2e9c862457278e91d7b0c95a43d 570 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 542 4.1E-126 T 29-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CSW12_RS29590 a508ead995475d605a802cc7ded1a5a9 113 SUPERFAMILY SSF52980 1 67 2.57E-13 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS29590 a508ead995475d605a802cc7ded1a5a9 113 Gene3D G3DSA:3.40.1350.10 1 93 6.6E-7 T 29-03-2018 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 Gene3D G3DSA:1.10.10.10 1 82 1.9E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 SUPERFAMILY SSF53850 89 291 5.32E-35 T 29-03-2018 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 Pfam PF03466 LysR substrate binding domain 87 291 8.4E-41 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 Gene3D G3DSA:3.40.190.10 90 179 1.2E-21 T 29-03-2018 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 SUPERFAMILY SSF46785 1 86 7.27E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 Gene3D G3DSA:3.40.190.10 180 264 2.9E-20 T 29-03-2018 CSW12_RS09405 b7d48abd59bcbfffdf4f65a6797badda 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-22 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS08585 46e9cb71361afff831b7b72687b380dc 296 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 9.0E-120 T 29-03-2018 IPR019991 GTP-binding protein, ribosome biogenesis CSW12_RS08585 46e9cb71361afff831b7b72687b380dc 296 Gene3D G3DSA:3.40.50.300 12 179 1.6E-31 T 29-03-2018 CSW12_RS08585 46e9cb71361afff831b7b72687b380dc 296 Gene3D G3DSA:1.10.1580.10 180 272 5.7E-26 T 29-03-2018 IPR023179 GTP-binding protein, orthogonal bundle domain CSW12_RS08585 46e9cb71361afff831b7b72687b380dc 296 PIRSF PIRSF006230 1 283 2.2E-106 T 29-03-2018 IPR016478 GTPase, MTG1 CSW12_RS08585 46e9cb71361afff831b7b72687b380dc 296 Pfam PF01926 50S ribosome-binding GTPase 123 213 2.9E-17 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS08585 46e9cb71361afff831b7b72687b380dc 296 SUPERFAMILY SSF52540 9 192 3.58E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03325 879f29ebc18e11f4a1f4193e81ed85c5 392 Pfam PF12704 MacB-like periplasmic core domain 21 230 3.2E-23 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CSW12_RS03325 879f29ebc18e11f4a1f4193e81ed85c5 392 Pfam PF02687 FtsX-like permease family 298 381 6.7E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.1E-66 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 454 657 2.8E-61 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 Gene3D G3DSA:3.40.1710.10 47 211 6.8E-30 T 29-03-2018 CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 Gene3D G3DSA:1.10.287.950 231 312 0.0023 T 29-03-2018 CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 Pfam PF12698 ABC-2 family transporter protein 24 165 1.2E-12 T 29-03-2018 CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 Pfam PF12698 ABC-2 family transporter protein 449 651 7.7E-9 T 29-03-2018 CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 Gene3D G3DSA:1.20.120.570 314 449 1.2E-14 T 29-03-2018 CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 415 440 1.7E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 261 286 1.1E-4 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 229 6.3E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS25825 97e5220575ddad489d5d63358c0c9fcd 666 SUPERFAMILY SSF101967 175 290 7.45E-6 T 29-03-2018 CSW12_RS16840 ec5ff160ac198dbb559d890feb1449d9 239 Pfam PF01553 Acyltransferase 60 184 6.5E-33 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CSW12_RS16840 ec5ff160ac198dbb559d890feb1449d9 239 SMART SM00563 74 188 3.2E-38 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CSW12_RS16840 ec5ff160ac198dbb559d890feb1449d9 239 Gene3D G3DSA:3.40.1130.10 24 239 2.3E-55 T 29-03-2018 CSW12_RS16840 ec5ff160ac198dbb559d890feb1449d9 239 SUPERFAMILY SSF69593 46 236 4.71E-52 T 29-03-2018 CSW12_RS16840 ec5ff160ac198dbb559d890feb1449d9 239 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 59 185 4.2E-38 T 29-03-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 CSW12_RS30980 673c7d5d87ed3f6ac643441f49e1862d 373 Pfam PF00877 NlpC/P60 family 260 370 2.6E-20 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CSW12_RS30980 673c7d5d87ed3f6ac643441f49e1862d 373 Gene3D G3DSA:1.10.530.10 52 229 4.3E-17 T 29-03-2018 CSW12_RS30980 673c7d5d87ed3f6ac643441f49e1862d 373 SUPERFAMILY SSF53955 66 176 1.05E-10 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS30980 673c7d5d87ed3f6ac643441f49e1862d 373 Pfam PF13702 Lysozyme-like 60 226 7.8E-48 T 29-03-2018 CSW12_RS30980 673c7d5d87ed3f6ac643441f49e1862d 373 Gene3D G3DSA:3.90.1720.10 239 372 3.3E-27 T 29-03-2018 CSW12_RS30980 673c7d5d87ed3f6ac643441f49e1862d 373 SUPERFAMILY SSF54001 243 372 6.62E-25 T 29-03-2018 CSW12_RS06005 c2d7c92d31d074724a49c13f36707192 307 Gene3D G3DSA:3.30.2350.10 84 306 4.7E-61 T 29-03-2018 CSW12_RS06005 c2d7c92d31d074724a49c13f36707192 307 Pfam PF00849 RNA pseudouridylate synthase 93 246 1.0E-32 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS06005 c2d7c92d31d074724a49c13f36707192 307 SUPERFAMILY SSF55120 79 299 7.36E-64 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS06005 c2d7c92d31d074724a49c13f36707192 307 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 301 2.4E-72 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS06005 c2d7c92d31d074724a49c13f36707192 307 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 136 150 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 Pfam PF00920 Dehydratase family 31 549 1.0E-226 T 29-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 SUPERFAMILY SSF52016 374 552 7.3E-60 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 552 2.1E-252 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 SUPERFAMILY SSF143975 1 373 7.59E-140 T 29-03-2018 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 47.145 T 29-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 29-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CSW12_RS18595 56c062b23c38563a8979071ae83c7398 557 Gene3D G3DSA:3.40.50.2300 43 258 3.2E-4 T 29-03-2018 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 Gene3D G3DSA:3.90.1150.10 5 211 1.3E-48 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 26 455 3.4E-175 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 Gene3D G3DSA:3.40.640.10 212 341 6.0E-47 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 SUPERFAMILY SSF53383 23 457 3.8E-135 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 Pfam PF00202 Aminotransferase class-III 41 455 1.2E-124 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 14 458 52.808 T 29-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 PIRSF PIRSF000521 41 458 8.8E-42 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 263 300 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20145 7d1c9c69eec9e7b1a6a6e0904e67985c 462 Gene3D G3DSA:3.90.1150.10 342 458 3.9E-16 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS27730 b3f54ff5258645be62fdabc96c5ccc3f 67 SMART SM00530 9 64 2.6E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS27730 b3f54ff5258645be62fdabc96c5ccc3f 67 SUPERFAMILY SSF47413 4 65 2.09E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS27730 b3f54ff5258645be62fdabc96c5ccc3f 67 Gene3D G3DSA:1.10.260.40 1 66 2.5E-20 T 29-03-2018 CSW12_RS27730 b3f54ff5258645be62fdabc96c5ccc3f 67 Pfam PF01381 Helix-turn-helix 10 64 8.2E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS13950 27b0887776443e20b688cd0efb0b9711 198 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 4 154 2.9E-51 T 29-03-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ CSW12_RS13950 27b0887776443e20b688cd0efb0b9711 198 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 25 152 1.9E-16 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CSW12_RS09035 50d833cc87de824e6a0798c909b035b7 303 Gene3D G3DSA:3.90.25.10 184 299 3.0E-18 T 29-03-2018 CSW12_RS09035 50d833cc87de824e6a0798c909b035b7 303 Gene3D G3DSA:3.40.50.720 3 183 2.6E-22 T 29-03-2018 CSW12_RS09035 50d833cc87de824e6a0798c909b035b7 303 SUPERFAMILY SSF51735 3 295 1.01E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS09035 50d833cc87de824e6a0798c909b035b7 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 230 8.6E-40 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 192 257 4.7E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 SUPERFAMILY SSF47384 183 259 1.14E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 Gene3D G3DSA:3.30.565.10 262 415 1.3E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 SMART SM00387 303 414 3.3E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 SUPERFAMILY SSF55874 248 412 4.71E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 354 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 368 1.1E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 Gene3D G3DSA:1.10.287.130 184 254 8.0E-15 T 29-03-2018 CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 412 5.9E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01575 1ff8a7da72508edc7e8cb0c2fb04b943 416 SMART SM00388 191 258 5.0E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27630 e869a53a17650dbac309029c58bc00ba 91 Gene3D G3DSA:3.10.290.10 1 89 2.5E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS27630 e869a53a17650dbac309029c58bc00ba 91 PIRSF PIRSF038881 1 88 5.8E-36 T 29-03-2018 IPR025490 RNA-binding protein, HP1423 type CSW12_RS27630 e869a53a17650dbac309029c58bc00ba 91 SMART SM00363 1 64 4.0E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS27630 e869a53a17650dbac309029c58bc00ba 91 Pfam PF01479 S4 domain 1 46 1.3E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS27630 e869a53a17650dbac309029c58bc00ba 91 SUPERFAMILY SSF55174 1 77 1.96E-20 T 29-03-2018 CSW12_RS00660 1935848a9f00a8b9af382d54345d4cd3 433 Gene3D G3DSA:1.20.1250.20 8 216 1.7E-34 T 29-03-2018 CSW12_RS00660 1935848a9f00a8b9af382d54345d4cd3 433 Pfam PF07690 Major Facilitator Superfamily 29 306 1.7E-33 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS00660 1935848a9f00a8b9af382d54345d4cd3 433 SUPERFAMILY SSF103473 10 431 2.35E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS00660 1935848a9f00a8b9af382d54345d4cd3 433 Gene3D G3DSA:1.20.1250.20 226 433 6.9E-29 T 29-03-2018 CSW12_RS28080 573d609e860643eae11d1f68ef6f605f 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.824 T 29-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CSW12_RS28080 573d609e860643eae11d1f68ef6f605f 146 SUPERFAMILY SSF52080 4 144 1.7E-50 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CSW12_RS28080 573d609e860643eae11d1f68ef6f605f 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 2.8E-56 T 29-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28080 573d609e860643eae11d1f68ef6f605f 146 Gene3D G3DSA:3.100.10.10 42 146 1.8E-33 T 29-03-2018 CSW12_RS28080 573d609e860643eae11d1f68ef6f605f 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 3.1E-38 T 29-03-2018 IPR021131 Ribosomal protein L18e/L15P CSW12_RS28080 573d609e860643eae11d1f68ef6f605f 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 29-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27830 49652cf69bd7133b7d79eb12f28c5f28 354 ProSitePatterns PS00112 Phosphagen kinase active site signature. 167 173 - T 29-03-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 CSW12_RS27830 49652cf69bd7133b7d79eb12f28c5f28 354 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 350 38.731 T 29-03-2018 IPR023660 Protein arginine kinase GO:0006950|GO:0016775 CSW12_RS27830 49652cf69bd7133b7d79eb12f28c5f28 354 SUPERFAMILY SSF55931 5 268 2.24E-88 T 29-03-2018 CSW12_RS27830 49652cf69bd7133b7d79eb12f28c5f28 354 Gene3D G3DSA:3.30.590.10 5 255 4.2E-85 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CSW12_RS27830 49652cf69bd7133b7d79eb12f28c5f28 354 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 55 252 8.3E-75 T 29-03-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 CSW12_RS06560 bded37016edbddc1fb5bfb1482eab2de 298 Pfam PF01063 Amino-transferase class IV 32 258 5.7E-60 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS06560 bded37016edbddc1fb5bfb1482eab2de 298 SUPERFAMILY SSF56752 4 291 5.23E-94 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS06560 bded37016edbddc1fb5bfb1482eab2de 298 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS06560 bded37016edbddc1fb5bfb1482eab2de 298 Gene3D G3DSA:3.20.10.10 135 285 1.5E-47 T 29-03-2018 CSW12_RS06560 bded37016edbddc1fb5bfb1482eab2de 298 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 289 2.6E-103 T 29-03-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 CSW12_RS06560 bded37016edbddc1fb5bfb1482eab2de 298 Gene3D G3DSA:3.30.470.10 1 134 2.1E-38 T 29-03-2018 CSW12_RS15700 f110a5e39ab770bc03fc032c455b1f16 228 SUPERFAMILY SSF56281 22 227 1.19E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS15700 f110a5e39ab770bc03fc032c455b1f16 228 SMART SM00849 19 222 3.7E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS15700 f110a5e39ab770bc03fc032c455b1f16 228 Pfam PF00753 Metallo-beta-lactamase superfamily 26 215 9.5E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS15700 f110a5e39ab770bc03fc032c455b1f16 228 Gene3D G3DSA:3.60.15.10 16 228 6.9E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 Gene3D G3DSA:1.10.10.10 1 68 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 SUPERFAMILY SSF46785 2 71 2.45E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 Pfam PF07702 UTRA domain 90 227 5.7E-37 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 SUPERFAMILY SSF64288 55 235 1.55E-43 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 5.2E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.3E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 SMART SM00866 89 228 2.9E-32 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 4 235 1.1E-106 T 29-03-2018 IPR012770 Trehalose operon transcriptional repressor CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 Gene3D G3DSA:3.40.1410.10 71 236 1.1E-32 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS01855 ac440fb290818c3f6efdcb55fe532149 236 SMART SM00345 8 67 4.3E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS29435 9f7c2d424cb620855cb714150c51d792 200 Pfam PF02661 Fic/DOC family 44 129 1.1E-12 T 29-03-2018 IPR003812 Fido domain CSW12_RS29435 9f7c2d424cb620855cb714150c51d792 200 SUPERFAMILY SSF140931 17 190 8.76E-42 T 29-03-2018 IPR003812 Fido domain CSW12_RS29435 9f7c2d424cb620855cb714150c51d792 200 Gene3D G3DSA:1.10.3290.10 8 171 6.5E-32 T 29-03-2018 IPR003812 Fido domain CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 SUPERFAMILY SSF101386 362 460 4.74E-23 T 29-03-2018 CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 204 4.9E-24 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 PIRSF PIRSF002845 1 486 2.9E-238 T 29-03-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 SUPERFAMILY SSF101386 232 332 5.89E-25 T 29-03-2018 CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 1.5E-28 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 392 451 1.6E-7 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 Gene3D G3DSA:1.10.287.1080 348 447 6.6E-25 T 29-03-2018 CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 Gene3D G3DSA:1.10.287.1080 232 347 2.6E-41 T 29-03-2018 CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 Gene3D G3DSA:3.40.1010.10 4 120 4.7E-18 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 TIGRFAM TIGR00444 mazG: MazG family protein 239 482 1.6E-101 T 29-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CSW12_RS27625 10ad82cbd2ba7003589602f76d20bed6 486 SUPERFAMILY SSF53790 3 263 3.34E-33 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS10995 a5ac0b27adbdf52aed50e4fbcbea8841 199 Pfam PF00881 Nitroreductase family 10 177 7.5E-17 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS10995 a5ac0b27adbdf52aed50e4fbcbea8841 199 Gene3D G3DSA:3.40.109.10 3 199 3.5E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS10995 a5ac0b27adbdf52aed50e4fbcbea8841 199 SUPERFAMILY SSF55469 4 198 5.1E-73 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SUPERFAMILY SSF52540 6 280 1.69E-112 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Pfam PF03764 Elongation factor G, domain IV 477 595 9.6E-47 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Gene3D G3DSA:3.40.50.300 1 285 9.0E-64 T 29-03-2018 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Gene3D G3DSA:3.30.230.10 489 611 6.8E-43 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 112.089 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SUPERFAMILY SSF50447 263 402 8.58E-37 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 5.5E-71 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 29-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SMART SM00889 478 596 1.3E-72 T 29-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SUPERFAMILY SSF54980 598 688 1.63E-31 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Gene3D G3DSA:3.30.70.870 400 488 7.9E-36 T 29-03-2018 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SUPERFAMILY SSF54980 400 478 6.83E-26 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Gene3D G3DSA:3.30.70.240 612 689 2.7E-34 T 29-03-2018 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SMART SM00838 598 685 2.9E-59 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 3.9E-44 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Pfam PF00679 Elongation factor G C-terminus 598 684 9.0E-33 T 29-03-2018 IPR000640 Elongation factor EFG, domain V-like CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.7E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.7E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.7E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.7E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.7E-17 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.2E-36 T 29-03-2018 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 SUPERFAMILY SSF54211 477 597 8.34E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Gene3D G3DSA:2.40.30.10 287 399 1.8E-31 T 29-03-2018 CSW12_RS27965 581bf17228f0ebb082a0ae8313650f93 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 2.6E-16 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CSW12_RS25035 f440f1705dc243b9732a8dfffb1f52d8 164 PIRSF PIRSF005028 1 162 2.1E-56 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CSW12_RS25035 f440f1705dc243b9732a8dfffb1f52d8 164 Gene3D G3DSA:3.30.70.1450 73 161 8.8E-18 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS25035 f440f1705dc243b9732a8dfffb1f52d8 164 SUPERFAMILY SSF116726 77 157 7.06E-18 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS25035 f440f1705dc243b9732a8dfffb1f52d8 164 Pfam PF02080 TrkA-C domain 89 158 1.9E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS03305 77b521e0b4e1ed31645bfe998c865967 436 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 426 5.3E-119 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CSW12_RS03305 77b521e0b4e1ed31645bfe998c865967 436 PIRSF PIRSF006351 1 434 6.3E-141 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS03305 77b521e0b4e1ed31645bfe998c865967 436 Pfam PF02378 Phosphotransferase system, EIIC 29 352 2.8E-59 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS27720 945e588becee45a579692b8b6cb57720 120 SUPERFAMILY SSF55620 2 119 1.95E-39 T 29-03-2018 CSW12_RS27720 945e588becee45a579692b8b6cb57720 120 SMART SM00905 4 117 4.4E-50 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CSW12_RS27720 945e588becee45a579692b8b6cb57720 120 Pfam PF02152 Dihydroneopterin aldolase 4 116 4.8E-36 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CSW12_RS27720 945e588becee45a579692b8b6cb57720 120 Gene3D G3DSA:3.30.1130.10 1 119 3.4E-37 T 29-03-2018 CSW12_RS27720 945e588becee45a579692b8b6cb57720 120 TIGRFAM TIGR00526 folB_dom: FolB domain 2 119 2.7E-38 T 29-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CSW12_RS27720 945e588becee45a579692b8b6cb57720 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 3.4E-42 T 29-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CSW12_RS16415 ab97e26202f42bff0cd583726d8df19b 176 Gene3D G3DSA:3.40.630.30 2 176 1.7E-23 T 29-03-2018 CSW12_RS16415 ab97e26202f42bff0cd583726d8df19b 176 Pfam PF13302 Acetyltransferase (GNAT) domain 9 149 5.8E-33 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS16415 ab97e26202f42bff0cd583726d8df19b 176 SUPERFAMILY SSF55729 3 173 2.36E-47 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17475 05064b76d1c2f15c40c118d537532aee 402 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 230 371 2.7E-23 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CSW12_RS17475 05064b76d1c2f15c40c118d537532aee 402 SUPERFAMILY SSF53756 1 392 9.77E-80 T 29-03-2018 CSW12_RS17475 05064b76d1c2f15c40c118d537532aee 402 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 7 394 6.2E-120 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CSW12_RS17475 05064b76d1c2f15c40c118d537532aee 402 Gene3D G3DSA:3.40.50.2000 236 379 1.9E-37 T 29-03-2018 CSW12_RS17475 05064b76d1c2f15c40c118d537532aee 402 Gene3D G3DSA:3.40.50.2000 3 235 1.7E-23 T 29-03-2018 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 Gene3D G3DSA:3.90.1150.10 360 478 3.6E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 SMART SM00345 17 76 2.1E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 Gene3D G3DSA:3.40.640.10 152 359 1.5E-45 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.8E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 Pfam PF00155 Aminotransferase class I and II 128 470 3.9E-33 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 SUPERFAMILY SSF46785 6 79 1.82E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 SUPERFAMILY SSF53383 111 475 2.42E-93 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.7E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS12460 84abf43e07e9f41e9693b4341ef6e759 483 Gene3D G3DSA:1.10.10.10 4 78 5.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 37.298 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 SUPERFAMILY SSF52418 73 338 4.06E-90 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 Pfam PF00591 Glycosyl transferase family, a/b domain 73 323 1.0E-91 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 SUPERFAMILY SSF47648 1 67 2.35E-15 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 Gene3D G3DSA:3.40.1030.10 68 341 5.5E-100 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 5 328 1.9E-116 T 29-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 1.1E-15 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS05725 dc3d07100bc38346c24a84ea29eb50eb 341 Gene3D G3DSA:1.20.970.10 1 66 8.4E-17 T 29-03-2018 CSW12_RS09630 db8179dab2023cc0ded687734792b8ff 147 ProSitePatterns PS00893 Nudix box signature. 36 57 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS09630 db8179dab2023cc0ded687734792b8ff 147 PRINTS PR00502 NUDIX hydrolase family signature 45 60 3.8E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS09630 db8179dab2023cc0ded687734792b8ff 147 PRINTS PR00502 NUDIX hydrolase family signature 31 45 3.8E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS09630 db8179dab2023cc0ded687734792b8ff 147 SUPERFAMILY SSF55811 9 126 4.6E-25 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS09630 db8179dab2023cc0ded687734792b8ff 147 Gene3D G3DSA:3.90.79.10 6 145 4.3E-26 T 29-03-2018 CSW12_RS09630 db8179dab2023cc0ded687734792b8ff 147 Pfam PF00293 NUDIX domain 7 118 8.6E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 Gene3D G3DSA:1.25.40.10 72 319 5.7E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 Gene3D G3DSA:1.10.260.40 8 71 6.5E-18 T 29-03-2018 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 SUPERFAMILY SSF47413 5 71 1.43E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 Pfam PF01381 Helix-turn-helix 10 64 7.7E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 SMART SM00530 9 64 6.6E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 SUPERFAMILY SSF48452 137 213 2.66E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11345 61f385348bc5f1a9b386102c8b59522e 374 SUPERFAMILY SSF48452 256 296 2.66E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS16385 1f8e2708c1064d39c781d1e49e5575ce 191 Gene3D G3DSA:2.60.120.40 44 182 1.9E-18 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS16385 1f8e2708c1064d39c781d1e49e5575ce 191 SUPERFAMILY SSF49842 47 165 9.94E-19 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SUPERFAMILY SSF55666 145 235 6.94E-30 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SUPERFAMILY SSF54211 8 144 2.83E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 2.6E-15 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SMART SM00316 621 691 1.7E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Gene3D G3DSA:3.30.230.70 12 252 2.3E-60 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Gene3D G3DSA:3.30.230.70 312 550 5.0E-57 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 1.0E-16 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF03725 3' exoribonuclease family, domain 2 460 528 2.0E-6 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 3.6E-18 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 4.3E-21 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SUPERFAMILY SSF55666 451 549 1.18E-28 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF00013 KH domain 557 615 1.4E-9 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Pfam PF00575 S1 RNA binding domain 620 691 8.9E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 692 0.0 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SMART SM00322 553 618 1.4E-12 T 29-03-2018 IPR004087 K Homology domain GO:0003676 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SUPERFAMILY SSF54791 556 641 4.93E-24 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.262 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Gene3D G3DSA:3.30.1370.10 551 615 1.4E-13 T 29-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 PIRSF PIRSF005499 2 712 5.6E-302 T 29-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SUPERFAMILY SSF50249 621 704 6.38E-22 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Gene3D G3DSA:1.10.10.400 253 311 7.9E-20 T 29-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 SUPERFAMILY SSF54211 293 489 3.24E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS08745 1775681a62d0c30f983993217fbce036 712 Gene3D G3DSA:2.40.50.140 616 699 3.7E-24 T 29-03-2018 CSW12_RS29875 71c7071304e7bde75fb9d32adfe47f4f 271 SUPERFAMILY SSF56784 53 246 6.35E-47 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS29875 71c7071304e7bde75fb9d32adfe47f4f 271 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 8 267 1.8E-94 T 29-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 CSW12_RS29875 71c7071304e7bde75fb9d32adfe47f4f 271 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 30 240 1.8E-51 T 29-03-2018 IPR005519 Acid phosphatase, class B-like CSW12_RS29875 71c7071304e7bde75fb9d32adfe47f4f 271 PIRSF PIRSF019271 1 270 2.6E-102 T 29-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 CSW12_RS29875 71c7071304e7bde75fb9d32adfe47f4f 271 Gene3D G3DSA:3.40.50.1000 41 208 7.4E-28 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 3.2E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.2E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.2E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 Gene3D G3DSA:1.10.10.10 6 147 3.2E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 Pfam PF01047 MarR family 36 94 2.5E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 SUPERFAMILY SSF46785 4 144 2.58E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21970 72e776c9acb3a20e5119e2472f2df84b 151 SMART SM00347 29 127 1.4E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS07750 6099ebd75d12a6039604b1eb07e0efff 220 Pfam PF10368 Putative cell-wall binding lipoprotein 13 213 1.8E-63 T 29-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CSW12_RS07750 6099ebd75d12a6039604b1eb07e0efff 220 SUPERFAMILY SSF140423 21 211 6.54E-57 T 29-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CSW12_RS07750 6099ebd75d12a6039604b1eb07e0efff 220 Gene3D G3DSA:1.20.120.570 11 208 1.7E-44 T 29-03-2018 CSW12_RS08905 fced7cfeafb11059ffb13d2b72626429 307 Gene3D G3DSA:3.20.20.140 1 306 7.5E-88 T 29-03-2018 CSW12_RS08905 fced7cfeafb11059ffb13d2b72626429 307 SUPERFAMILY SSF51556 1 306 3.81E-75 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS08905 fced7cfeafb11059ffb13d2b72626429 307 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 305 1.8E-100 T 29-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 SUPERFAMILY SSF56601 295 661 4.23E-104 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 SUPERFAMILY SSF56601 245 264 4.23E-104 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 639 2.7E-176 T 29-03-2018 CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 Gene3D G3DSA:1.10.3810.10 76 277 1.8E-78 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 Gene3D G3DSA:3.40.710.10 280 708 6.2E-102 T 29-03-2018 CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 Pfam PF00912 Transglycosylase 84 260 6.5E-64 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 636 9.9E-43 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS11820 44b63a519703416b0d82e7ec7ad4c2a6 853 SUPERFAMILY SSF53955 73 283 7.87E-72 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 SUPERFAMILY SSF63380 1 89 1.36E-27 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 PIRSF PIRSF000498 1 208 4.4E-76 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 Gene3D G3DSA:2.40.30.20 1 92 2.2E-31 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 SUPERFAMILY SSF63380 92 195 2.81E-31 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 197 1.3E-78 T 29-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 Gene3D G3DSA:2.40.30.20 93 190 1.1E-29 T 29-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 Pfam PF00677 Lumazine binding domain 3 86 6.9E-25 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20100 f440bef9480022cbbf4cef7f89e6787c 214 Pfam PF00677 Lumazine binding domain 99 183 7.9E-21 T 29-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS26610 1d71ee3e811273fcf617e91cba6e9d0e 328 PIRSF PIRSF028757 1 328 5.7E-80 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS26610 1d71ee3e811273fcf617e91cba6e9d0e 328 Pfam PF02016 LD-carboxypeptidase 12 314 5.2E-75 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS26610 1d71ee3e811273fcf617e91cba6e9d0e 328 SUPERFAMILY SSF52317 2 166 5.49E-46 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS26610 1d71ee3e811273fcf617e91cba6e9d0e 328 Gene3D G3DSA:3.50.30.60 159 328 2.2E-44 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS26610 1d71ee3e811273fcf617e91cba6e9d0e 328 Gene3D G3DSA:3.40.50.10740 1 158 7.0E-51 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CSW12_RS26610 1d71ee3e811273fcf617e91cba6e9d0e 328 SUPERFAMILY SSF141986 166 318 6.41E-35 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS05785 4077f687b9d7f58fe416ddb6a3489dc7 411 SMART SM01324 331 410 1.7E-26 T 29-03-2018 IPR025582 YARHG domain CSW12_RS05785 4077f687b9d7f58fe416ddb6a3489dc7 411 Pfam PF13308 YARHG domain 332 411 1.1E-23 T 29-03-2018 IPR025582 YARHG domain CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 PIRSF PIRSF000850 290 377 40.0 T 29-03-2018 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 PIRSF PIRSF000850 203 308 2.9E-4 T 29-03-2018 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 PIRSF PIRSF000850 26 120 0.18 T 29-03-2018 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 SMART SM00155 310 337 2.3E-6 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 SMART SM00155 138 165 5.8E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 Pfam PF13091 PLD-like domain 57 198 3.1E-16 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 Pfam PF13091 PLD-like domain 238 364 1.5E-30 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 SUPERFAMILY SSF56024 190 380 8.75E-44 T 29-03-2018 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 Gene3D G3DSA:3.30.870.10 230 386 8.5E-31 T 29-03-2018 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 SUPERFAMILY SSF56024 18 228 2.02E-49 T 29-03-2018 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 28 393 1.4E-104 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CSW12_RS26525 acfe77aef783b6cd52e2ef1fa47fbcba 397 Gene3D G3DSA:3.30.870.10 22 209 1.4E-33 T 29-03-2018 CSW12_RS20930 57c543fc805780a1f97a478c2999e418 66 SUPERFAMILY SSF158379 1 61 1.7E-22 T 29-03-2018 IPR023164 YqgQ-like domain CSW12_RS20930 57c543fc805780a1f97a478c2999e418 66 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 4.0E-27 T 29-03-2018 IPR009256 Protein of unknown function DUF910 CSW12_RS20930 57c543fc805780a1f97a478c2999e418 66 Gene3D G3DSA:1.10.287.760 1 65 2.2E-29 T 29-03-2018 IPR023164 YqgQ-like domain CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 Gene3D G3DSA:3.30.450.40 87 250 1.3E-41 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 Gene3D G3DSA:1.10.10.10 3 86 2.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 SUPERFAMILY SSF46785 6 74 7.54E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 Pfam PF01614 Bacterial transcriptional regulator 120 244 2.0E-33 T 29-03-2018 IPR014757 Transcription regulator IclR, C-terminal CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 SMART SM00346 4 92 3.9E-23 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 Pfam PF09339 IclR helix-turn-helix domain 7 55 6.6E-11 T 29-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CSW12_RS12290 8366e0e48fe9c5c9c922907a9f00e4e5 250 SUPERFAMILY SSF55781 60 248 3.79E-46 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Pfam PF08239 Bacterial SH3 domain 354 396 3.7E-6 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 SUPERFAMILY SSF55846 157 317 2.22E-45 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Pfam PF00395 S-layer homology domain 481 524 1.2E-8 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Pfam PF00395 S-layer homology domain 427 466 1.2E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Pfam PF00395 S-layer homology domain 545 587 1.8E-7 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Gene3D G3DSA:2.30.30.410 323 424 4.4E-9 T 29-03-2018 CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 SMART SM00644 167 305 4.7E-26 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 176 298 2.3E-23 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS11525 3458e4dc1187046ea255102091ddd06b 599 Gene3D G3DSA:3.40.80.10 157 318 2.1E-34 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 SUPERFAMILY SSF111304 1 198 5.23E-79 T 29-03-2018 IPR023627 Recombination protein RecR CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 110.865 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 29-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 SMART SM00493 80 165 3.8E-18 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 7.0E-90 T 29-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 Gene3D G3DSA:3.40.1360.10 77 170 6.0E-41 T 29-03-2018 CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 Pfam PF13662 Toprim domain 80 171 1.5E-26 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS27445 0de2c9d36102a34005c0078a53d9d313 198 Pfam PF02132 RecR protein 40 78 1.3E-15 T 29-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 1.2E-57 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 801 0.0 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Pfam PF08264 Anticodon-binding domain of tRNA 651 766 2.4E-22 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Gene3D G3DSA:3.40.50.620 1 305 3.3E-101 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Gene3D G3DSA:3.40.50.620 378 604 1.2E-68 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.8E-17 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 SUPERFAMILY SSF50677 224 407 6.07E-55 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 801 23.305 T 29-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 2.0E-70 T 29-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Gene3D G3DSA:1.10.730.10 605 740 5.8E-33 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 603 1.6E-20 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 SUPERFAMILY SSF47323 618 801 3.92E-44 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 SUPERFAMILY SSF52374 2 224 4.59E-146 T 29-03-2018 CSW12_RS23385 498c2497d4e0ed607343fb2136d7cc7b 802 SUPERFAMILY SSF52374 411 625 4.59E-146 T 29-03-2018 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 Gene3D G3DSA:3.40.50.1370 166 330 3.0E-54 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 2.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 2.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 2.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 307 318 2.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 2.4E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 273 8.5E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 8.5E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 8.5E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 293 316 8.5E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 151 2.4E-47 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 328 9.2E-127 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 Gene3D G3DSA:3.40.50.1370 9 165 7.7E-59 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 326 1.5E-56 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 SUPERFAMILY SSF53671 7 330 6.15E-106 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS00705 28d0309e78b7e5b7ad74ca070d94e1b3 332 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 329 83.52 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CSW12_RS20970 bba852aeb20ba8dd7f083671adba6626 305 Gene3D G3DSA:3.40.190.10 160 303 5.7E-15 T 29-03-2018 CSW12_RS20970 bba852aeb20ba8dd7f083671adba6626 305 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 32 288 6.6E-80 T 29-03-2018 IPR011862 Phosphate binding protein GO:0006810 CSW12_RS20970 bba852aeb20ba8dd7f083671adba6626 305 Pfam PF12849 PBP superfamily domain 32 256 1.3E-22 T 29-03-2018 IPR024370 PBP domain CSW12_RS20970 bba852aeb20ba8dd7f083671adba6626 305 SUPERFAMILY SSF53850 32 301 1.32E-63 T 29-03-2018 CSW12_RS20970 bba852aeb20ba8dd7f083671adba6626 305 Gene3D G3DSA:3.40.190.10 32 159 5.8E-30 T 29-03-2018 CSW12_RS20955 fbefa0390da64292d45fcd2bcf76a076 271 SMART SM00382 49 258 7.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS20955 fbefa0390da64292d45fcd2bcf76a076 271 Pfam PF00005 ABC transporter 40 196 3.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS20955 fbefa0390da64292d45fcd2bcf76a076 271 Gene3D G3DSA:3.40.50.300 10 269 7.2E-60 T 29-03-2018 CSW12_RS20955 fbefa0390da64292d45fcd2bcf76a076 271 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS20955 fbefa0390da64292d45fcd2bcf76a076 271 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 25 271 3.4E-126 T 29-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CSW12_RS20955 fbefa0390da64292d45fcd2bcf76a076 271 SUPERFAMILY SSF52540 20 258 3.87E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02230 a386725559f4093fca36583311f00198 721 SUPERFAMILY SSF48371 132 297 7.83E-7 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS02230 a386725559f4093fca36583311f00198 721 Gene3D G3DSA:1.20.5.1230 229 308 6.0E-8 T 29-03-2018 CSW12_RS02230 a386725559f4093fca36583311f00198 721 Gene3D G3DSA:1.20.5.1230 4 228 6.2E-20 T 29-03-2018 CSW12_RS02230 a386725559f4093fca36583311f00198 721 Gene3D G3DSA:1.10.287.700 362 424 1.3E-9 T 29-03-2018 CSW12_RS02230 a386725559f4093fca36583311f00198 721 Gene3D G3DSA:1.10.287.700 425 670 1.8E-13 T 29-03-2018 CSW12_RS01480 cfa5f4f74ca2aa5f67f96324a64dd2a1 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 8 499 2.8E-185 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CSW12_RS01480 cfa5f4f74ca2aa5f67f96324a64dd2a1 516 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 499 1.7E-148 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CSW12_RS01480 cfa5f4f74ca2aa5f67f96324a64dd2a1 516 ProSitePatterns PS01303 BCCT family of transporters signature. 316 325 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 639 651 - T 29-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 PIRSF PIRSF000460 3 801 4.1E-234 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 Gene3D G3DSA:3.40.50.2000 1 464 1.9E-180 T 29-03-2018 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 Pfam PF00343 Carbohydrate phosphorylase 93 795 0.0 T 29-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 5 795 0.0 T 29-03-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 Gene3D G3DSA:3.40.50.2000 465 780 3.1E-128 T 29-03-2018 CSW12_RS24075 544b2bc13d159d5e967f24cc7558f635 802 SUPERFAMILY SSF53756 4 796 9.42E-302 T 29-03-2018 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 SUPERFAMILY SSF64518 1 271 6.02E-82 T 29-03-2018 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 138 1.1E-35 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 Gene3D G3DSA:1.20.1330.10 38 243 2.0E-56 T 29-03-2018 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 Pfam PF00700 Bacterial flagellin C-terminal helical region 186 270 4.7E-24 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 PRINTS PR00207 Flagellin signature 74 93 2.7E-18 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 PRINTS PR00207 Flagellin signature 109 132 2.7E-18 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19270 a6350273213ba86c691edad67468b6a5 271 PRINTS PR00207 Flagellin signature 35 52 2.7E-18 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 Gene3D G3DSA:1.25.40.70 295 357 1.4E-10 T 29-03-2018 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 Gene3D G3DSA:1.25.40.70 171 294 3.2E-13 T 29-03-2018 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SUPERFAMILY SSF48371 207 372 5.76E-32 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 86 1.6E-19 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 Pfam PF13646 HEAT repeats 267 351 2.5E-12 T 29-03-2018 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SMART SM00567 E-Z type HEAT repeats 279 308 17.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SMART SM00567 E-Z type HEAT repeats 219 246 650.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SMART SM00567 E-Z type HEAT repeats 310 339 1.6E-5 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SMART SM00567 E-Z type HEAT repeats 248 277 0.32 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 Gene3D G3DSA:3.30.1370.70 2 89 2.6E-20 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SMART SM00932 4 90 8.1E-28 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 SUPERFAMILY SSF110836 3 88 2.88E-23 T 29-03-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal CSW12_RS17110 6429d1328b248e522f7ef92ca4669bc1 376 Pfam PF13769 Virulence factor 107 185 2.2E-28 T 29-03-2018 IPR025989 Virulence factor domain CSW12_RS09060 353390c5c8fc77eec71ef5667a8e3170 191 PIRSF PIRSF000709 2 180 7.8E-4 T 29-03-2018 CSW12_RS09060 353390c5c8fc77eec71ef5667a8e3170 191 SUPERFAMILY SSF53254 1 181 1.54E-27 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS09060 353390c5c8fc77eec71ef5667a8e3170 191 Gene3D G3DSA:3.40.50.1240 1 187 4.8E-27 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS09060 353390c5c8fc77eec71ef5667a8e3170 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 177 1.8E-23 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Gene3D G3DSA:3.30.230.10 231 398 5.7E-68 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Gene3D G3DSA:3.30.565.10 21 230 5.3E-74 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 7.8E-30 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 118 132 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 426 440 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 274 287 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 530 542 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 492 508 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 572 588 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR00418 DNA topoisomerase II family signature 510 527 1.9E-71 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF00204 DNA gyrase B 227 396 2.0E-64 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 179 5.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 318 334 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 366 380 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 380 400 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 476 485 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 226 248 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.0E-76 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 SUPERFAMILY SSF55874 11 219 4.32E-73 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 SUPERFAMILY SSF54211 227 397 6.07E-63 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 SUPERFAMILY SSF56719 400 632 1.2E-91 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 SMART SM00387 36 180 4.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 640 0.0 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Pfam PF01751 Toprim domain 425 536 2.5E-19 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 SMART SM00433 40 633 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 640 101.599 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS27330 bb74aea3ef89623741ee15a51c5a746c 640 Gene3D G3DSA:3.40.50.670 405 637 3.2E-104 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS12440 7340850c3e05f3ea21309b2a877d2eb9 180 Pfam PF04229 GrpB protein 18 180 3.6E-43 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CSW12_RS12440 7340850c3e05f3ea21309b2a877d2eb9 180 Gene3D G3DSA:3.30.460.10 13 180 6.3E-47 T 29-03-2018 CSW12_RS12440 7340850c3e05f3ea21309b2a877d2eb9 180 SUPERFAMILY SSF81301 20 180 2.91E-39 T 29-03-2018 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Gene3D G3DSA:1.10.3500.10 109 351 2.5E-83 T 29-03-2018 IPR023323 Tex-like domain CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SUPERFAMILY SSF50249 636 722 8.21E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SMART SM00732 324 422 8.0E-32 T 29-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Gene3D G3DSA:1.10.3500.10 352 496 3.7E-41 T 29-03-2018 IPR023323 Tex-like domain CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SUPERFAMILY SSF47781 468 554 5.45E-26 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Pfam PF16921 Tex protein YqgF-like domain 324 449 8.3E-56 T 29-03-2018 IPR032639 Tex protein, YqgF-like domain CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Gene3D G3DSA:1.10.10.650 9 108 1.1E-32 T 29-03-2018 IPR023319 Tex-like protein, HTH domain CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Pfam PF09371 Tex-like protein N-terminal domain 17 199 2.4E-71 T 29-03-2018 IPR018974 Tex-like protein, N-terminal CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Gene3D G3DSA:2.40.50.140 642 724 6.3E-24 T 29-03-2018 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SMART SM00316 650 721 4.5E-22 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SUPERFAMILY SSF53098 320 467 3.57E-49 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Gene3D G3DSA:1.10.150.310 497 631 1.2E-43 T 29-03-2018 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SUPERFAMILY SSF47781 559 633 1.69E-14 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Pfam PF00575 S1 RNA binding domain 650 720 1.3E-16 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 SUPERFAMILY SSF158832 11 319 1.18E-116 T 29-03-2018 CSW12_RS28710 797fcf942efb2eeedc3a0c79d8cd2c0e 724 Pfam PF12836 Helix-hairpin-helix motif 489 553 6.0E-26 T 29-03-2018 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 Gene3D G3DSA:3.30.565.10 212 367 1.6E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 SMART SM00387 253 364 3.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 206 2.4E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 Gene3D G3DSA:1.10.287.130 116 204 1.6E-13 T 29-03-2018 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 SUPERFAMILY SSF47384 127 208 2.75E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 SMART SM00304 81 133 5.1E-5 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 343 2.1E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 SUPERFAMILY SSF158472 89 132 1.96E-5 T 29-03-2018 CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 362 8.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 SUPERFAMILY SSF55874 197 362 5.63E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23980 afe39f2397165ce9df8ef47e63a77576 368 SMART SM00388 141 208 3.7E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 3.2E-121 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Pfam PF02491 SHS2 domain inserted in FTSA 83 160 5.9E-24 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 SMART SM00842 7 194 2.2E-92 T 29-03-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.90.640.10 246 298 6.3E-23 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 206 219 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 SUPERFAMILY SSF53067 6 192 8.43E-57 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 SUPERFAMILY SSF53067 197 368 1.08E-41 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.30.420.40 1 184 6.9E-33 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Gene3D G3DSA:3.30.420.40 195 245 8.5E-6 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 434 30.519 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 PIRSF PIRSF003101 1 434 1.1E-144 T 29-03-2018 IPR020823 Cell division protein FtsA GO:0007049 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Pfam PF14450 Cell division protein FtsA 9 188 4.5E-10 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Pfam PF14450 Cell division protein FtsA 205 366 2.9E-22 T 29-03-2018 CSW12_RS08220 82ebb5c6a9af57005d25258349328445 435 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 370 435 1.3E-8 T 29-03-2018 IPR021873 Cell division protein FtsA, C-terminal CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 SUPERFAMILY SSF100920 354 510 2.22E-60 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 SUPERFAMILY SSF53067 161 352 2.22E-66 T 29-03-2018 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 Pfam PF00012 Hsp70 protein 76 573 7.8E-217 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.3E-80 T 29-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 SUPERFAMILY SSF100934 477 575 1.7E-11 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 607 36.839 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 Gene3D G3DSA:1.20.1270.10 502 588 2.3E-19 T 29-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 2.9E-281 T 29-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 Gene3D G3DSA:3.30.420.40 1 170 2.8E-69 T 29-03-2018 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 Gene3D G3DSA:3.30.420.40 171 333 5.5E-48 T 29-03-2018 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 29-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 Gene3D G3DSA:2.60.34.10 360 501 3.6E-66 T 29-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CSW12_RS21190 1a96bc3855e6002184a166d71607e9f5 611 SUPERFAMILY SSF53067 1 157 6.31E-58 T 29-03-2018 CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 Gene3D G3DSA:1.10.10.10 223 282 1.1E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 SMART SM00316 69 136 36.0 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 SMART SM00316 4 64 1.9 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 SMART SM00316 151 213 1.6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 PIRSF PIRSF012524 1 284 1.4E-105 T 29-03-2018 IPR014464 Conserved virulence factor B CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 Gene3D G3DSA:2.40.50.140 56 137 1.3E-4 T 29-03-2018 CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 Gene3D G3DSA:2.40.50.140 152 222 2.7E-9 T 29-03-2018 CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 SUPERFAMILY SSF50249 154 213 9.19E-6 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS05315 7aed43b6f70a29ff33b479ab6ce607f7 284 Pfam PF13509 S1 domain 5 64 1.1E-20 T 29-03-2018 CSW12_RS17945 11df4ce324eeb13f0040ec9854a8fa52 412 Pfam PF00501 AMP-binding enzyme 83 279 1.9E-20 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS17945 11df4ce324eeb13f0040ec9854a8fa52 412 ProSitePatterns PS00455 Putative AMP-binding domain signature. 107 118 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS17945 11df4ce324eeb13f0040ec9854a8fa52 412 Gene3D G3DSA:3.30.300.30 313 407 9.3E-18 T 29-03-2018 CSW12_RS17945 11df4ce324eeb13f0040ec9854a8fa52 412 SUPERFAMILY SSF56801 101 405 8.11E-57 T 29-03-2018 CSW12_RS17945 11df4ce324eeb13f0040ec9854a8fa52 412 Pfam PF13193 AMP-binding enzyme C-terminal domain 328 399 1.8E-11 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS17945 11df4ce324eeb13f0040ec9854a8fa52 412 Gene3D G3DSA:3.40.50.980 101 266 1.1E-22 T 29-03-2018 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 Gene3D G3DSA:3.30.420.40 1 246 7.5E-61 T 29-03-2018 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 249 8.7E-52 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 SUPERFAMILY SSF53067 4 252 3.2E-57 T 29-03-2018 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 SUPERFAMILY SSF53067 251 501 1.09E-48 T 29-03-2018 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 Gene3D G3DSA:3.30.420.40 247 512 9.8E-45 T 29-03-2018 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 PIRSF PIRSF000538 1 508 1.8E-126 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS12795 6b2f429a54e9d5e36b27a10941b31191 520 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 286 456 3.8E-19 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 Gene3D G3DSA:3.90.660.10 216 428 1.3E-44 T 29-03-2018 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 Gene3D G3DSA:1.10.405.10 136 215 7.9E-25 T 29-03-2018 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 SUPERFAMILY SSF54373 316 426 4.38E-33 T 29-03-2018 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 SUPERFAMILY SSF51905 23 335 1.81E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 SUPERFAMILY SSF51905 437 477 1.81E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 Gene3D G3DSA:3.50.50.60 5 61 1.1E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 Gene3D G3DSA:3.50.50.60 429 478 0.053 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 Pfam PF01593 Flavin containing amine oxidoreductase 34 475 6.0E-66 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 Gene3D G3DSA:3.90.660.10 62 135 1.9E-20 T 29-03-2018 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 PRINTS PR00757 Flavin-containing amine oxidase signature 407 426 1.9E-11 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 PRINTS PR00757 Flavin-containing amine oxidase signature 457 474 1.9E-11 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 PRINTS PR00757 Flavin-containing amine oxidase signature 26 45 1.9E-11 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS18225 c066ee38f6b839f01b2d123c1b2bf22d 478 PRINTS PR00757 Flavin-containing amine oxidase signature 320 339 1.9E-11 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS11335 318b1fff7c9409207c2dd79a93096dc2 158 SUPERFAMILY SSF55826 6 157 2.35E-37 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS11335 318b1fff7c9409207c2dd79a93096dc2 158 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 1.2E-61 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CSW12_RS11335 318b1fff7c9409207c2dd79a93096dc2 158 Pfam PF04073 Aminoacyl-tRNA editing domain 36 147 1.4E-19 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS11335 318b1fff7c9409207c2dd79a93096dc2 158 Gene3D G3DSA:3.90.960.10 1 158 2.5E-34 T 29-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CSW12_RS11335 318b1fff7c9409207c2dd79a93096dc2 158 PIRSF PIRSF006181 1 158 2.7E-60 T 29-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Pfam PF03061 Thioesterase superfamily 352 425 7.3E-10 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 SMART SM00116 200 248 0.11 T 29-03-2018 IPR000644 CBS domain CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 SMART SM00116 259 307 4.7E-8 T 29-03-2018 IPR000644 CBS domain CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Gene3D G3DSA:3.40.1390.20 70 186 1.7E-27 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Pfam PF00571 CBS domain 191 246 3.8E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Pfam PF00571 CBS domain 254 307 3.0E-9 T 29-03-2018 IPR000644 CBS domain CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Pfam PF07085 DRTGG domain 76 178 8.6E-30 T 29-03-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 SUPERFAMILY SSF54637 335 436 3.44E-16 T 29-03-2018 IPR029069 HotDog domain CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Gene3D G3DSA:3.10.580.10 187 302 2.1E-26 T 29-03-2018 CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 SUPERFAMILY SSF46785 5 54 1.7E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Gene3D G3DSA:3.10.129.10 303 437 5.9E-24 T 29-03-2018 CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 58 1.0E-4 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 SUPERFAMILY SSF75138 72 185 2.49E-29 T 29-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 SUPERFAMILY SSF54631 182 306 1.2E-30 T 29-03-2018 CSW12_RS22680 71b14ce0890a1363a5ab1e95d73d26c0 437 Gene3D G3DSA:1.10.10.10 1 69 4.8E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Pfam PF03193 RsgA GTPase 59 225 1.3E-62 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Pfam PF16745 RsgA N-terminal domain 3 56 1.0E-24 T 29-03-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 283 3.1E-88 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Gene3D G3DSA:1.10.40.50 227 293 1.8E-24 T 29-03-2018 CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 SUPERFAMILY SSF50249 1 63 4.28E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 SUPERFAMILY SSF52540 64 291 5.59E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 2 290 39.727 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Gene3D G3DSA:2.40.50.140 1 61 1.8E-21 T 29-03-2018 CSW12_RS08465 5b8d24b0f5afc946e301fc2a5a5bf74d 293 Gene3D G3DSA:3.40.50.300 62 225 6.3E-26 T 29-03-2018 CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 174 2.0E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 SUPERFAMILY SSF88946 14 111 4.71E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 Pfam PF04542 Sigma-70 region 2 38 95 9.1E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 Gene3D G3DSA:1.10.10.10 108 177 1.6E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 Pfam PF08281 Sigma-70, region 4 122 170 2.9E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 SUPERFAMILY SSF88659 114 174 5.05E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS09800 92bc41e082f6543e34aa96ce7fd02d5d 177 Gene3D G3DSA:1.10.1740.10 8 107 3.0E-16 T 29-03-2018 CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 324 3.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 3.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 305 3.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 3.7E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 216 322 1.6E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 Gene3D G3DSA:3.30.565.10 131 323 4.5E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 SMART SM00387 215 327 2.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23900 6f54fa90c8fefcc6a9c77afab4e3aaa0 340 SUPERFAMILY SSF55874 162 323 1.83E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 SUPERFAMILY SSF88723 1 172 2.4E-47 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 Gene3D G3DSA:3.40.50.1010 2 186 9.0E-61 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 SMART SM00279 175 210 2.5E-14 T 29-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 259 7.9E-26 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 SUPERFAMILY SSF47807 173 278 1.06E-26 T 29-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 170 6.0E-51 T 29-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 SMART SM00475 2 263 3.2E-107 T 29-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CSW12_RS19675 9064e5a962460591220ab99bdbe9ba6b 288 Gene3D G3DSA:1.10.150.20 187 263 1.9E-24 T 29-03-2018 CSW12_RS06305 85a1871898ff855c72312b48a4f24688 119 SUPERFAMILY SSF52218 1 117 1.32E-24 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS06305 85a1871898ff855c72312b48a4f24688 119 TIGRFAM TIGR00333 nrdI: nrdI protein 3 117 7.5E-40 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CSW12_RS06305 85a1871898ff855c72312b48a4f24688 119 Pfam PF07972 NrdI Flavodoxin like 3 110 3.1E-32 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CSW12_RS06305 85a1871898ff855c72312b48a4f24688 119 Hamap MF_00128 Protein NrdI [nrdI]. 1 119 26.56 T 29-03-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial CSW12_RS06305 85a1871898ff855c72312b48a4f24688 119 PIRSF PIRSF005087 1 119 1.6E-41 T 29-03-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI CSW12_RS06305 85a1871898ff855c72312b48a4f24688 119 Gene3D G3DSA:3.40.50.360 1 119 1.1E-20 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 Pfam PF00717 Peptidase S24-like 127 191 6.8E-17 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 Gene3D G3DSA:1.10.10.10 5 74 1.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 SUPERFAMILY SSF46785 7 74 2.16E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 Gene3D G3DSA:2.10.109.10 92 209 1.5E-26 T 29-03-2018 CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 Pfam PF01726 LexA DNA binding domain 5 69 1.3E-30 T 29-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 124 134 2.8E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 164 176 2.8E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 135 146 2.8E-12 T 29-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 TIGRFAM TIGR00498 lexA: repressor LexA 5 209 1.4E-78 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 SUPERFAMILY SSF51306 86 207 7.85E-36 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS09295 8e8d5122a9be77f9939d31d101bc0ca1 210 Hamap MF_00015 LexA repressor [lexA]. 7 209 35.608 T 29-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 SMART SM01232 134 226 2.1E-44 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 Pfam PF06827 Zinc finger found in FPG and IleRS 246 275 2.4E-10 T 29-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 SUPERFAMILY SSF81624 2 139 1.7E-42 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 SUPERFAMILY SSF46946 134 223 1.83E-29 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 29-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 44.453 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.3E-107 T 29-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 Gene3D G3DSA:1.10.8.50 127 274 2.2E-46 T 29-03-2018 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 224 2.7E-29 T 29-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 2.6E-34 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 SMART SM00898 2 118 1.2E-51 T 29-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 SUPERFAMILY SSF57716 222 274 1.49E-17 T 29-03-2018 CSW12_RS22550 ea1b27de2d58faf35ce9332fe0fb59b6 276 Gene3D G3DSA:3.20.190.10 2 126 2.1E-41 T 29-03-2018 CSW12_RS10705 d5a50258a29c0a43045c0d147ed21aca 93 Gene3D G3DSA:3.30.1390.10 20 93 4.0E-9 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 Hamap MF_00323 Ferrochelatase [hemH]. 3 307 30.679 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 ProSitePatterns PS00534 Ferrochelatase signature. 177 195 - T 29-03-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 Gene3D G3DSA:3.40.50.1400 156 288 7.8E-38 T 29-03-2018 CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 SUPERFAMILY SSF53800 2 305 1.47E-88 T 29-03-2018 CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 Gene3D G3DSA:3.40.50.1400 1 155 9.5E-27 T 29-03-2018 CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 Pfam PF00762 Ferrochelatase 4 306 2.7E-82 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS04670 b8a84918cc316b0f9470e7916c5bcfff 311 TIGRFAM TIGR00109 hemH: ferrochelatase 2 307 1.5E-96 T 29-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 Gene3D G3DSA:1.10.357.10 57 194 3.2E-21 T 29-03-2018 CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 SUPERFAMILY SSF46689 6 81 4.0E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 Gene3D G3DSA:1.10.10.60 2 56 2.6E-12 T 29-03-2018 CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 3.2E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 SUPERFAMILY SSF48498 77 191 4.75E-20 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS18380 4f7b1d3a3e964b792a93812295367375 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.4E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS23355 c022866ef34008c3fbffca92164c39ee 702 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 227 677 1.4E-143 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS23355 c022866ef34008c3fbffca92164c39ee 702 Gene3D G3DSA:1.25.40.20 81 564 6.6E-4 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS16920 f130d4c31718cd96691bc63739873bff 146 SUPERFAMILY SSF55729 1 143 1.89E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS16920 f130d4c31718cd96691bc63739873bff 146 Pfam PF00583 Acetyltransferase (GNAT) family 32 133 1.3E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS16920 f130d4c31718cd96691bc63739873bff 146 Gene3D G3DSA:3.40.630.30 1 82 1.6E-11 T 29-03-2018 CSW12_RS16920 f130d4c31718cd96691bc63739873bff 146 Gene3D G3DSA:3.40.630.30 83 145 1.6E-10 T 29-03-2018 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 263 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 251 6.9E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 267 6.9E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 SUPERFAMILY SSF46689 167 218 7.47E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 SUPERFAMILY SSF46689 220 272 8.06E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 Gene3D G3DSA:3.90.1240.10 74 234 5.7E-19 T 29-03-2018 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 SMART SM00342 184 267 3.4E-25 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 Pfam PF12833 Helix-turn-helix domain 193 268 9.6E-20 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 Gene3D G3DSA:1.10.10.60 235 273 1.3E-13 T 29-03-2018 CSW12_RS11560 077ce3fdbbe13916e3768bba5ea46cc2 275 SUPERFAMILY SSF51215 15 151 2.48E-7 T 29-03-2018 CSW12_RS28385 c3160d0f338333d18267ee73954db117 334 SUPERFAMILY SSF161098 98 295 2.94E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28385 c3160d0f338333d18267ee73954db117 334 Gene3D G3DSA:1.10.3720.10 25 301 3.4E-40 T 29-03-2018 CSW12_RS28385 c3160d0f338333d18267ee73954db117 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 312 5.8E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28385 c3160d0f338333d18267ee73954db117 334 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 81 4.4E-7 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CSW12_RS25415 eb44b8604d7836e9b4d945850287cc78 161 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 36 144 1.3E-6 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CSW12_RS29240 11346a737591a25b832811e066bb3d7f 884 SUPERFAMILY SSF52540 373 721 3.68E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS29240 11346a737591a25b832811e066bb3d7f 884 Gene3D G3DSA:3.40.50.300 235 742 5.0E-10 T 29-03-2018 CSW12_RS01785 b169cf140f6935fb52b161abd18fa9a1 322 SUPERFAMILY SSF53807 44 316 5.69E-72 T 29-03-2018 CSW12_RS01785 b169cf140f6935fb52b161abd18fa9a1 322 Gene3D G3DSA:3.40.50.1980 159 322 3.1E-38 T 29-03-2018 CSW12_RS01785 b169cf140f6935fb52b161abd18fa9a1 322 Gene3D G3DSA:3.40.50.1980 30 158 4.7E-33 T 29-03-2018 CSW12_RS01785 b169cf140f6935fb52b161abd18fa9a1 322 Pfam PF01497 Periplasmic binding protein 62 296 1.1E-36 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 SUPERFAMILY SSF52540 327 573 5.43E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 Pfam PF00005 ABC transporter 354 501 7.1E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 SMART SM00382 363 555 8.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 Gene3D G3DSA:3.40.50.300 324 579 2.0E-73 T 29-03-2018 CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 Pfam PF00664 ABC transporter transmembrane region 21 292 9.2E-42 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 Gene3D G3DSA:1.20.1560.10 3 323 2.4E-60 T 29-03-2018 CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS03600 48e468ea2ae66b478fa07d678342a764 586 SUPERFAMILY SSF90123 8 325 1.44E-73 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 311 1.2E-37 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 SUPERFAMILY SSF51735 4 145 1.56E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 1.2E-49 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 4.7E-134 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 Gene3D G3DSA:3.90.110.10 147 313 4.7E-49 T 29-03-2018 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 Gene3D G3DSA:3.40.50.720 7 146 3.7E-40 T 29-03-2018 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 SUPERFAMILY SSF56327 146 312 8.65E-58 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 PIRSF PIRSF000102 2 313 8.3E-115 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 6.0E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 6.0E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 6.0E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 6.0E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 6.0E-49 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS18230 547947ea72cc19da4ab24a70503015da 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 47.943 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS04345 845c218d6f3057aef1bed45b85d493c9 103 Gene3D G3DSA:3.30.110.70 1 103 4.1E-35 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CSW12_RS04345 845c218d6f3057aef1bed45b85d493c9 103 Pfam PF01906 Putative heavy-metal-binding 1 103 6.2E-38 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS04345 845c218d6f3057aef1bed45b85d493c9 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.629 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS04345 845c218d6f3057aef1bed45b85d493c9 103 SUPERFAMILY SSF117782 1 103 1.28E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS28455 e6ca890b5c0ad73524b8d51e43d5071c 268 SUPERFAMILY SSF53850 42 265 9.58E-68 T 29-03-2018 CSW12_RS28455 e6ca890b5c0ad73524b8d51e43d5071c 268 Pfam PF13531 Bacterial extracellular solute-binding protein 43 264 2.7E-49 T 29-03-2018 CSW12_RS28455 e6ca890b5c0ad73524b8d51e43d5071c 268 PIRSF PIRSF004846 1 268 8.7E-90 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CSW12_RS28455 e6ca890b5c0ad73524b8d51e43d5071c 268 Gene3D G3DSA:3.40.190.10 40 136 6.8E-16 T 29-03-2018 CSW12_RS28455 e6ca890b5c0ad73524b8d51e43d5071c 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 48 263 1.4E-69 T 29-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CSW12_RS28455 e6ca890b5c0ad73524b8d51e43d5071c 268 Gene3D G3DSA:3.40.190.10 137 227 4.9E-38 T 29-03-2018 CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 Gene3D G3DSA:3.40.50.300 37 448 1.5E-18 T 29-03-2018 CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 SMART SM00491 503 627 1.9E-7 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 Gene3D G3DSA:3.40.50.300 465 644 1.4E-14 T 29-03-2018 CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 SUPERFAMILY SSF52540 53 108 8.09E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 SUPERFAMILY SSF52540 198 280 8.09E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 SUPERFAMILY SSF52540 421 623 8.09E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19775 ef7ac3f33dc05a90a6c8aca362363995 645 Pfam PF13307 Helicase C-terminal domain 488 621 1.2E-24 T 29-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.273 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 SUPERFAMILY SSF81271 282 363 6.1E-37 T 29-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:1.10.150.300 110 189 7.4E-30 T 29-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:3.10.20.30 268 365 9.9E-48 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 8.7E-41 T 29-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.5E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.5E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.5E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.5E-35 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 SUPERFAMILY SSF52540 3 304 1.21E-89 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Pfam PF01926 50S ribosome-binding GTPase 5 123 9.7E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 PIRSF PIRSF006641 1 366 8.8E-167 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:3.40.50.300 1 80 9.8E-8 T 29-03-2018 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 Gene3D G3DSA:3.40.50.300 190 267 0.047 T 29-03-2018 CSW12_RS27240 a94bd8ce1ea39c9ef8f297c797fbc11a 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 1.1E-160 T 29-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 Pfam PF07664 Ferrous iron transport protein B C terminus 451 503 1.8E-18 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 SUPERFAMILY SSF52540 3 162 4.91E-34 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 Pfam PF07670 Nucleoside recognition 508 631 9.6E-34 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 Pfam PF07670 Nucleoside recognition 347 440 1.4E-15 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 50 65 5.5E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 5.5E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 628 8.3E-195 T 29-03-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 Pfam PF02421 Ferrous iron transport protein B 3 153 6.1E-59 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CSW12_RS23775 562dc284b33f3e3b659594757a81a8b7 662 Gene3D G3DSA:3.40.50.300 3 310 1.4E-26 T 29-03-2018 CSW12_RS27000 34a81e66eb22058478495f1ee8a82fea 356 Pfam PF02898 Nitric oxide synthase, oxygenase domain 4 355 1.4E-164 T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CSW12_RS27000 34a81e66eb22058478495f1ee8a82fea 356 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 65 72 - T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CSW12_RS27000 34a81e66eb22058478495f1ee8a82fea 356 SUPERFAMILY SSF56512 3 355 3.79E-167 T 29-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CSW12_RS27000 34a81e66eb22058478495f1ee8a82fea 356 Gene3D G3DSA:3.90.1230.10 193 302 5.7E-52 T 29-03-2018 CSW12_RS27000 34a81e66eb22058478495f1ee8a82fea 356 PIRSF PIRSF037219 1 356 8.5E-191 T 29-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CSW12_RS27000 34a81e66eb22058478495f1ee8a82fea 356 Gene3D G3DSA:3.90.340.10 1 125 2.2E-44 T 29-03-2018 CSW12_RS17690 806d211dba80bb033feaac1f22384509 358 Pfam PF08757 CotH kinase protein 43 350 1.2E-85 T 29-03-2018 IPR014867 Spore coat protein CotH CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 SUPERFAMILY SSF75625 1 238 4.32E-80 T 29-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 Pfam PF01709 Transcriptional regulator 4 235 1.6E-80 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.842 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 55.025 T 29-03-2018 IPR026562 Probable transcriptional regulatory protein YeeN CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 Gene3D G3DSA:1.10.10.200 2 76 8.8E-26 T 29-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 Gene3D G3DSA:3.30.70.980 172 239 7.8E-9 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 Gene3D G3DSA:3.30.70.980 80 171 2.2E-25 T 29-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS01400 3b0ce688696d5cec0104abb49158b25c 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 4.8E-71 T 29-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:2.40.30.10 206 300 2.1E-31 T 29-03-2018 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 2.4E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.4E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.4E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.4E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.4E-24 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF52540 6 219 9.26E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 29-03-2018 IPR031157 Tr-type G domain, conserved site CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF50465 303 395 1.35E-34 T 29-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 9.2E-18 T 29-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 60.149 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:3.40.50.300 1 74 4.6E-11 T 29-03-2018 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 SUPERFAMILY SSF50447 203 300 1.3E-30 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 4.6E-60 T 29-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.4E-230 T 29-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:2.40.30.10 301 394 1.7E-30 T 29-03-2018 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Gene3D G3DSA:3.40.50.300 75 203 6.0E-32 T 29-03-2018 CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 3.7E-32 T 29-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CSW12_RS27970 1783a9623dddb36694ba8a0db44dcb95 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 3.4E-15 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS04290 25bd7c15500423a6f3d23f68a2663390 160 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 2 156 1.2E-70 T 29-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CSW12_RS04290 25bd7c15500423a6f3d23f68a2663390 160 Pfam PF13581 Histidine kinase-like ATPase domain 12 140 1.1E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04290 25bd7c15500423a6f3d23f68a2663390 160 Gene3D G3DSA:3.30.565.10 3 154 1.8E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04290 25bd7c15500423a6f3d23f68a2663390 160 SUPERFAMILY SSF55874 31 135 2.36E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04290 25bd7c15500423a6f3d23f68a2663390 160 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 156 40.471 T 29-03-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CSW12_RS23400 b1935d6144f424cd983a793992ca566c 165 Gene3D G3DSA:3.30.70.1450 72 161 3.2E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS23400 b1935d6144f424cd983a793992ca566c 165 Pfam PF02080 TrkA-C domain 89 158 1.2E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS23400 b1935d6144f424cd983a793992ca566c 165 PIRSF PIRSF005028 1 161 8.4E-52 T 29-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CSW12_RS23400 b1935d6144f424cd983a793992ca566c 165 SUPERFAMILY SSF116726 69 156 1.57E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 SUPERFAMILY SSF142695 203 374 6.15E-74 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 8.8E-86 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 55.684 T 29-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 42.207 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 208 395 1.7E-80 T 29-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 SUPERFAMILY SSF55821 2 201 2.75E-86 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 Gene3D G3DSA:3.90.870.10 1 210 7.7E-96 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 3.3E-82 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 PIRSF PIRSF001259 1 397 4.4E-190 T 29-03-2018 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 Pfam PF00925 GTP cyclohydrolase II 206 371 5.4E-77 T 29-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CSW12_RS20105 3e8f2f99d23a1304b00d8994abf7b86b 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 39.044 T 29-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 SMART SM00421 146 203 1.3E-13 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 Gene3D G3DSA:3.40.50.2300 1 120 2.7E-23 T 29-03-2018 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.3E-9 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 SMART SM00448 2 114 8.6E-18 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 201 4.9E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 SUPERFAMILY SSF52172 1 125 3.56E-24 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 Gene3D G3DSA:1.10.10.10 121 213 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 SUPERFAMILY SSF46894 137 209 2.93E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS25400 b30ae753bc6fc60441b998f2f8637526 213 Pfam PF00072 Response regulator receiver domain 4 114 5.6E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 Gene3D G3DSA:3.30.230.40 90 194 2.2E-32 T 29-03-2018 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 Gene3D G3DSA:3.30.230.40 2 88 5.6E-30 T 29-03-2018 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 6.2E-65 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 29-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 40.238 T 29-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 SUPERFAMILY SSF54211 3 85 3.29E-29 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS06615 18d35311b8bf30a5d3e302d8ae89d3a4 194 SUPERFAMILY SSF54211 87 179 1.64E-35 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS10750 a7826ed2e6792cb685491ff446bf91a6 249 PIRSF PIRSF006648 1 249 9.0E-67 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CSW12_RS10750 a7826ed2e6792cb685491ff446bf91a6 249 Pfam PF01061 ABC-2 type transporter 5 214 1.9E-24 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CSW12_RS17860 1342fbcfccc56a785aed37425c06c834 95 Gene3D G3DSA:2.10.260.10 1 48 2.7E-19 T 29-03-2018 CSW12_RS17860 1342fbcfccc56a785aed37425c06c834 95 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 48 1.3E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS17860 1342fbcfccc56a785aed37425c06c834 95 SUPERFAMILY SSF89447 1 51 1.23E-15 T 29-03-2018 CSW12_RS17860 1342fbcfccc56a785aed37425c06c834 95 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 49 2.6E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS17860 1342fbcfccc56a785aed37425c06c834 95 SMART SM00966 8 51 4.8E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 Pfam PF00905 Penicillin binding protein transpeptidase domain 317 589 5.5E-36 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 Gene3D G3DSA:3.40.710.10 243 619 2.0E-83 T 29-03-2018 CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 Gene3D G3DSA:1.10.3810.10 43 241 1.1E-80 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 SUPERFAMILY SSF53955 40 244 7.87E-75 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 SUPERFAMILY SSF56601 258 609 4.0E-96 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 SUPERFAMILY SSF56601 207 229 4.0E-96 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 Pfam PF00912 Transglycosylase 51 225 3.5E-67 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS04660 ca8a047abef5e40ee1930cf19efe0d2f 705 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 61 593 4.2E-172 T 29-03-2018 CSW12_RS08420 d393f186bffdb3a9261f8ce406c37ad8 70 Gene3D G3DSA:3.90.940.10 1 70 9.9E-19 T 29-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CSW12_RS08420 d393f186bffdb3a9261f8ce406c37ad8 70 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 7.3E-22 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS08420 d393f186bffdb3a9261f8ce406c37ad8 70 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 13.24 T 29-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS08420 d393f186bffdb3a9261f8ce406c37ad8 70 SUPERFAMILY SSF63562 1 65 6.98E-20 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CSW12_RS08420 d393f186bffdb3a9261f8ce406c37ad8 70 Pfam PF01192 RNA polymerase Rpb6 9 59 2.6E-12 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CSW12_RS08420 d393f186bffdb3a9261f8ce406c37ad8 70 SMART SM01409 8 61 1.5E-12 T 29-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CSW12_RS20825 9bd0f0b68ccb43e59fec7b8099749319 231 Pfam PF12840 Helix-turn-helix domain 7 63 5.4E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20825 9bd0f0b68ccb43e59fec7b8099749319 231 SUPERFAMILY SSF46785 1 204 1.12E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20825 9bd0f0b68ccb43e59fec7b8099749319 231 Gene3D G3DSA:3.30.1380.20 55 230 6.5E-10 T 29-03-2018 CSW12_RS20825 9bd0f0b68ccb43e59fec7b8099749319 231 Pfam PF14196 L-2-amino-thiazoline-4-carboxylic acid hydrolase 111 227 9.1E-6 T 29-03-2018 IPR026002 L-2-amino-thiazoline-4-carboxylic acid hydrolase CSW12_RS20825 9bd0f0b68ccb43e59fec7b8099749319 231 Gene3D G3DSA:1.10.10.10 12 54 4.2E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24880 4205595d70721ebb614f110f949ff537 436 PIRSF PIRSF006060 1 436 1.5E-81 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS24880 4205595d70721ebb614f110f949ff537 436 Pfam PF13520 Amino acid permease 11 406 1.2E-61 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS08350 df339f9adbb297250d3e9999ab2c5ad3 84 Pfam PF10852 Protein of unknown function (DUF2651) 6 78 1.2E-29 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CSW12_RS08350 df339f9adbb297250d3e9999ab2c5ad3 84 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 1 84 9.0E-38 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 Gene3D G3DSA:3.40.50.720 1 237 6.5E-33 T 29-03-2018 CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.0E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 Pfam PF00106 short chain dehydrogenase 3 193 9.9E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03500 12af29efa32cdf11420a3116ee9d0c4d 256 SUPERFAMILY SSF51735 2 227 1.01E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07790 e41b9cb372388571a717ecb7aef189bb 162 Pfam PF13158 Protein of unknown function (DUF3993) 9 124 1.3E-47 T 29-03-2018 IPR025056 Protein of unknown function DUF3993 CSW12_RS26750 f2e917e1edeea8d7c74de1d1f12e4b32 95 Pfam PF17261 Family of unknown function (DUF5327) 1 95 7.2E-23 T 29-03-2018 IPR035218 Protein of unknown function DUF5327 CSW12_RS26750 f2e917e1edeea8d7c74de1d1f12e4b32 95 ProDom PD705231 YWDI GROUP-SPECIFIC 1 95 9.0E-39 T 29-03-2018 IPR035218 Protein of unknown function DUF5327 CSW12_RS01225 a1a764634d5e301409286c2c0efb4f24 93 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 11 89 5.4E-31 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 CSW12_RS01225 a1a764634d5e301409286c2c0efb4f24 93 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 18 89 5.0E-28 T 29-03-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 SUPERFAMILY SSF50129 6 147 4.87E-30 T 29-03-2018 IPR011032 GroES-like CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 Gene3D G3DSA:3.90.180.10 4 136 5.1E-29 T 29-03-2018 CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 SMART SM00829 13 321 6.2E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 2.9E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 Pfam PF00107 Zinc-binding dehydrogenase 154 257 2.1E-14 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 Gene3D G3DSA:3.40.50.720 137 312 4.3E-22 T 29-03-2018 CSW12_RS04360 ba8ccfa34a98c42946e4d457ae806d9f 323 SUPERFAMILY SSF51735 116 292 2.03E-32 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18910 1c3e4f8496ebdf89c01cdb4e687779bb 228 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 12 225 1.5E-9 T 29-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 Gene3D G3DSA:3.40.710.10 327 708 7.4E-76 T 29-03-2018 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 Pfam PF00905 Penicillin binding protein transpeptidase domain 357 693 1.6E-69 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 Gene3D G3DSA:3.90.1310.10 34 326 3.2E-37 T 29-03-2018 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 311 2.2E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 SUPERFAMILY SSF56519 62 123 2.49E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 SUPERFAMILY SSF56519 196 326 2.49E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS12330 beeede133f7d3170b11e5e4b7e4830b2 717 SUPERFAMILY SSF56601 328 700 1.11E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS02440 346e5458d1b799dcf3d45bd0fcc7773a 208 Pfam PF04989 Cephalosporin hydroxylase 22 207 2.0E-65 T 29-03-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 CSW12_RS02440 346e5458d1b799dcf3d45bd0fcc7773a 208 SUPERFAMILY SSF53335 10 206 3.33E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS02440 346e5458d1b799dcf3d45bd0fcc7773a 208 Gene3D G3DSA:3.40.50.150 27 199 2.4E-6 T 29-03-2018 CSW12_RS21950 381967356d60d2b5a9b008b82f41bb45 250 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 243 3.4E-62 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21950 381967356d60d2b5a9b008b82f41bb45 250 Gene3D G3DSA:3.40.50.10090 38 154 5.0E-28 T 29-03-2018 CSW12_RS21950 381967356d60d2b5a9b008b82f41bb45 250 SUPERFAMILY SSF69618 6 247 1.44E-60 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS21950 381967356d60d2b5a9b008b82f41bb45 250 Gene3D G3DSA:3.40.50.10090 155 250 7.1E-22 T 29-03-2018 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:1.20.120.140 1 92 3.8E-30 T 29-03-2018 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:1.10.260.30 328 432 9.9E-39 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 445 35.923 T 29-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 6.8E-80 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:1.20.120.140 196 311 2.9E-32 T 29-03-2018 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 SMART SM00962 101 297 4.1E-122 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 SUPERFAMILY SSF52540 43 355 4.48E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Pfam PF02978 Signal peptide binding domain 329 427 8.7E-34 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 SMART SM00382 100 302 2.9E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 1.8E-22 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 Gene3D G3DSA:3.40.50.300 99 169 2.0E-11 T 29-03-2018 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 SMART SM00963 2 87 4.9E-34 T 29-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 SUPERFAMILY SSF47446 329 430 1.8E-37 T 29-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CSW12_RS08550 66b9bed48dfb6f7c7615b61153269fa1 449 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 8.8E-191 T 29-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 5.4E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 5.4E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 5.4E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 5.4E-25 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 SUPERFAMILY SSF47323 431 556 3.73E-35 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 SMART SM00836 437 556 5.3E-55 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 94 4.2E-25 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 SUPERFAMILY SSF52374 118 448 2.17E-95 T 29-03-2018 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Gene3D G3DSA:3.40.50.620 113 367 4.8E-59 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Pfam PF05746 DALR anticodon binding domain 438 556 2.3E-36 T 29-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 SMART SM01016 5 95 6.6E-35 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Pfam PF00750 tRNA synthetases class I (R) 107 404 3.1E-25 T 29-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 556 7.4E-170 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 556 28.223 T 29-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Gene3D G3DSA:3.30.1360.70 3 112 1.6E-33 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 Gene3D G3DSA:1.10.730.10 403 556 1.5E-47 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS26600 1ced48180f7cb8fa3ead49920508f122 556 SUPERFAMILY SSF55190 6 115 4.84E-27 T 29-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.9E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 SUPERFAMILY SSF46894 128 227 1.25E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 SMART SM00448 2 112 1.7E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 Gene3D G3DSA:1.10.10.10 128 229 7.2E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 SMART SM00862 149 225 5.6E-18 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 Gene3D G3DSA:3.40.50.2300 1 127 3.8E-31 T 29-03-2018 CSW12_RS23895 1786ef014e2618df072e930f953badc3 231 SUPERFAMILY SSF52172 1 123 6.83E-35 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 Gene3D G3DSA:1.20.91.10 239 322 4.8E-16 T 29-03-2018 CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 Gene3D G3DSA:3.30.70.1450 536 609 7.0E-15 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 Pfam PF02080 TrkA-C domain 542 608 2.1E-11 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 Pfam PF00999 Sodium/hydrogen exchanger family 12 385 6.6E-74 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 Pfam PF02254 TrkA-N domain 399 508 1.8E-9 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 SUPERFAMILY SSF51735 396 539 1.53E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 Gene3D G3DSA:3.40.50.720 398 529 4.0E-17 T 29-03-2018 CSW12_RS02695 a8ccd22825a04749fcaa6eb8bc782b74 609 SUPERFAMILY SSF116726 538 608 5.89E-13 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS13995 dadd57251d65dfdd433fa653605ca3ab 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 2.5E-11 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS13995 dadd57251d65dfdd433fa653605ca3ab 308 SMART SM00829 10 305 2.0E-29 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS13995 dadd57251d65dfdd433fa653605ca3ab 308 SUPERFAMILY SSF50129 1 144 3.96E-36 T 29-03-2018 IPR011032 GroES-like CSW12_RS13995 dadd57251d65dfdd433fa653605ca3ab 308 Gene3D G3DSA:3.90.180.10 1 308 3.0E-71 T 29-03-2018 CSW12_RS13995 dadd57251d65dfdd433fa653605ca3ab 308 Pfam PF13602 Zinc-binding dehydrogenase 187 305 3.7E-25 T 29-03-2018 CSW12_RS13995 dadd57251d65dfdd433fa653605ca3ab 308 SUPERFAMILY SSF51735 117 239 3.36E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS22335 a81a7c17f7220e148ae3ab24bc1ff054 291 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 2 290 4.2E-135 T 29-03-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 CSW12_RS22335 a81a7c17f7220e148ae3ab24bc1ff054 291 Gene3D G3DSA:3.40.50.1980 139 291 1.0E-32 T 29-03-2018 CSW12_RS22335 a81a7c17f7220e148ae3ab24bc1ff054 291 SUPERFAMILY SSF53807 36 291 1.22E-52 T 29-03-2018 CSW12_RS22335 a81a7c17f7220e148ae3ab24bc1ff054 291 Pfam PF01497 Periplasmic binding protein 39 267 2.8E-40 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS22335 a81a7c17f7220e148ae3ab24bc1ff054 291 Gene3D G3DSA:3.40.50.1980 37 138 4.9E-18 T 29-03-2018 CSW12_RS03235 d3d26cc2f2a35f1edd72fc062e1e4b17 119 SUPERFAMILY SSF52821 8 118 4.85E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03235 d3d26cc2f2a35f1edd72fc062e1e4b17 119 Pfam PF00581 Rhodanese-like domain 33 118 3.4E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03235 d3d26cc2f2a35f1edd72fc062e1e4b17 119 Gene3D G3DSA:3.40.250.10 27 119 2.0E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03235 d3d26cc2f2a35f1edd72fc062e1e4b17 119 SMART SM00450 30 119 5.7E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 PIRSF PIRSF005963 1 298 1.4E-136 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 Gene3D G3DSA:3.20.20.70 12 266 2.6E-28 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 Pfam PF04055 Radical SAM superfamily 64 223 8.5E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 2 292 1.7E-121 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 SMART SM00729 57 264 1.5E-14 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 146.406 T 29-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 5 45 1.9E-10 T 29-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CSW12_RS24670 7c7572e1f641bcf01b6cd2979ba273ee 298 SUPERFAMILY SSF102114 20 287 8.24E-66 T 29-03-2018 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 98 6.7E-32 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 Gene3D G3DSA:3.10.20.70 2 104 1.9E-37 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 29-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 29-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 2.7E-185 T 29-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.5E-140 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 SUPERFAMILY SSF55931 105 442 1.37E-130 T 29-03-2018 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 29-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 SUPERFAMILY SSF54368 5 104 6.93E-35 T 29-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 SMART SM01230 105 354 1.2E-141 T 29-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CSW12_RS09275 b919b615a5531a56dcbffbab349d1fa9 444 Gene3D G3DSA:3.30.590.10 105 444 4.3E-130 T 29-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 39.269 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 PIRSF PIRSF002162 1 178 5.8E-50 T 29-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 29-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 6.0E-77 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 Gene3D G3DSA:3.90.930.12 2 83 8.6E-31 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 Gene3D G3DSA:3.90.930.12 84 179 1.9E-40 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 SUPERFAMILY SSF56053 84 177 2.65E-35 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 Pfam PF00347 Ribosomal protein L6 11 83 3.4E-23 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 Pfam PF00347 Ribosomal protein L6 91 165 2.2E-21 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 SUPERFAMILY SSF56053 1 83 7.67E-27 T 29-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 2.4E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 2.4E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS28060 3fb7e44f20606291de31e782260accc9 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 2.4E-34 T 29-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 29-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 SMART SM01210 325 416 9.6E-44 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Gene3D G3DSA:3.30.1490.20 85 187 9.4E-26 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 SUPERFAMILY SSF56059 102 312 2.3E-61 T 29-03-2018 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Gene3D G3DSA:3.40.50.20 2 84 2.0E-36 T 29-03-2018 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 42.457 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 SUPERFAMILY SSF51246 324 416 9.42E-28 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 8.5E-84 T 29-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 414 6.6E-27 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Gene3D G3DSA:3.30.470.20 189 323 1.6E-56 T 29-03-2018 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 SMART SM01209 101 293 1.8E-131 T 29-03-2018 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 1.0E-35 T 29-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 Gene3D G3DSA:3.90.600.10 325 416 1.0E-30 T 29-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 SUPERFAMILY SSF52440 1 101 4.75E-35 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS00075 c383c99934b4e9678a0f046da0367f94 423 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 3.9E-169 T 29-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS12490 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS12490 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS01065 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS01065 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS16060 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS16060 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS28555 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS28555 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS26745 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS26745 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS13920 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS13920 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS05850 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS05850 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS11365 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS11365 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS12410 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS12410 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS11040 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS11040 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS15270 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS15270 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS06730 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS06730 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS17105 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS17105 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS00730 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS00730 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS04820 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS04820 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS01660 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS01660 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS13885 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS13885 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS03770 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS03770 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS16480 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS16480 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS12360 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS12360 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS07175 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS07175 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS30425 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS30425 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS16395 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS16395 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS16220 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS16220 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS23585 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS23585 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS13025 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS13025 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS21975 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS21975 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS30325 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS30325 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS04910 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS04910 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS20265 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS20265 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS21260 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS21260 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS04615 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS04615 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS07075 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS07075 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS16705 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS16705 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS08385 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 279 365 1.1E-24 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS08385 3f0a11f57f4b35c6c3d7f1d0577017c4 409 Pfam PF01548 Transposase 5 165 1.8E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 SMART SM00387 349 461 4.5E-37 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 3.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 458 3.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 3.0E-12 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 Pfam PF00672 HAMP domain 187 233 2.2E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 SMART SM00304 185 237 5.4E-13 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 SMART SM00388 238 304 2.9E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 303 2.5E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 SUPERFAMILY SSF47384 221 304 5.3E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 458 3.2E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 SUPERFAMILY SSF55874 294 457 1.26E-46 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 Gene3D G3DSA:3.30.450.20 29 158 8.1E-7 T 29-03-2018 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 Gene3D G3DSA:3.30.565.10 308 464 9.7E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 SUPERFAMILY SSF158472 186 233 1.29E-11 T 29-03-2018 CSW12_RS06045 3fee3d4fa1e1bad30613e5f68c90e00c 466 Gene3D G3DSA:1.10.287.130 228 300 1.2E-18 T 29-03-2018 CSW12_RS20595 4637914c01120bf1f6d2955da21b8fe6 306 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 56 297 4.0E-139 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CSW12_RS20595 4637914c01120bf1f6d2955da21b8fe6 306 Pfam PF07136 Protein of unknown function (DUF1385) 56 300 8.0E-79 T 29-03-2018 IPR010787 Protein of unknown function DUF1385 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 Gene3D G3DSA:3.40.50.620 1 124 1.7E-29 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 PRINTS PR00147 DNA photolyase signature 136 152 4.9E-22 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 PRINTS PR00147 DNA photolyase signature 340 358 4.9E-22 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 PRINTS PR00147 DNA photolyase signature 320 336 4.9E-22 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 PRINTS PR00147 DNA photolyase signature 379 393 4.9E-22 T 29-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 Pfam PF00875 DNA photolyase 6 156 3.8E-42 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 Gene3D G3DSA:1.10.579.10 289 474 1.9E-82 T 29-03-2018 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 SUPERFAMILY SSF48173 186 474 8.5E-114 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 SUPERFAMILY SSF52425 4 171 6.54E-48 T 29-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 Gene3D G3DSA:1.25.40.80 125 288 3.4E-36 T 29-03-2018 CSW12_RS12065 7b7cee26f4aa70cc2786c2f7f0eef7cb 476 Pfam PF03441 FAD binding domain of DNA photolyase 271 470 2.5E-90 T 29-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 SUPERFAMILY SSF88946 7 109 7.06E-20 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 Pfam PF08281 Sigma-70, region 4 115 167 1.4E-17 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 Gene3D G3DSA:1.10.10.10 105 180 1.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 SUPERFAMILY SSF88659 108 172 2.62E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 Gene3D G3DSA:1.10.1740.10 1 101 2.7E-17 T 29-03-2018 CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 171 2.1E-25 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22955 fcfac68dc6e8c992fb0792a1a0126cbe 181 Pfam PF04542 Sigma-70 region 2 30 92 4.0E-11 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS00675 85f0fe85786f376ee67e9e5fc9ff376d 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 211 1.6E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS00675 85f0fe85786f376ee67e9e5fc9ff376d 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 105 5.6E-26 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CSW12_RS00675 85f0fe85786f376ee67e9e5fc9ff376d 230 SUPERFAMILY SSF161098 10 212 3.27E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS00675 85f0fe85786f376ee67e9e5fc9ff376d 230 Gene3D G3DSA:1.10.3720.10 2 216 3.0E-47 T 29-03-2018 CSW12_RS04545 6258362355356b522d5a3eac337d0e59 247 Gene3D G3DSA:3.40.50.300 1 232 2.1E-60 T 29-03-2018 CSW12_RS04545 6258362355356b522d5a3eac337d0e59 247 SMART SM00382 29 213 1.8E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS04545 6258362355356b522d5a3eac337d0e59 247 Pfam PF00005 ABC transporter 20 163 1.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS04545 6258362355356b522d5a3eac337d0e59 247 SUPERFAMILY SSF52540 4 231 1.11E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30255 d2b49de021ff7e4747821a461b234b78 188 SUPERFAMILY SSF159941 1 182 2.62E-50 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS30255 d2b49de021ff7e4747821a461b234b78 188 Gene3D G3DSA:3.10.290.30 1 182 1.6E-49 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS30255 d2b49de021ff7e4747821a461b234b78 188 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 3 178 3.2E-49 T 29-03-2018 IPR012912 Plasmid pRiA4b, Orf3 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 410 42.932 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 SUPERFAMILY SSF51338 370 416 3.09E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 SUPERFAMILY SSF51338 2 73 3.09E-23 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 Pfam PF01979 Amidohydrolase family 69 411 8.1E-21 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 SUPERFAMILY SSF51556 72 370 2.4E-80 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 TIGRFAM TIGR01224 hutI: imidazolonepropionase 33 409 6.1E-156 T 29-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 Gene3D G3DSA:3.20.20.140 88 370 5.7E-50 T 29-03-2018 CSW12_RS09500 473681811fe7a0703c366d0703f409fb 423 Gene3D G3DSA:2.30.40.10 1 87 4.4E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:1.10.8.60 492 584 2.7E-32 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 SUPERFAMILY SSF54211 595 770 1.4E-55 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 11 201 9.4E-40 T 29-03-2018 IPR003111 Lon, substrate-binding domain CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 SMART SM00464 10 202 1.7E-68 T 29-03-2018 IPR003111 Lon, substrate-binding domain CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:3.30.230.10 585 772 6.5E-67 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Hamap MF_01973 Lon protease [lon]. 11 772 72.904 T 29-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 673 692 6.3E-53 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 356 375 6.3E-53 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 595 611 6.3E-53 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 703 722 6.3E-53 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 726 744 6.3E-53 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 352 489 3.9E-24 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 SUPERFAMILY SSF52540 313 588 8.16E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 PIRSF PIRSF001174 1 775 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 570 772 8.3E-98 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 SUPERFAMILY SSF88697 11 201 1.54E-44 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 SMART SM00382 348 493 1.0E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:3.40.50.300 313 491 2.1E-33 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 TIGRFAM TIGR00763 lon: endopeptidase La 12 771 0.0 T 29-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 676 684 - T 29-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:1.10.4060.10 121 211 8.5E-27 T 29-03-2018 CSW12_RS21990 0b5f767dae56b9988d092b38fda48f83 776 Gene3D G3DSA:2.30.130.40 9 119 7.0E-25 T 29-03-2018 CSW12_RS13280 effe0efa52d5012732949da243d75053 236 Pfam PF04519 Polymer-forming cytoskeletal 20 81 9.2E-9 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CSW12_RS13280 effe0efa52d5012732949da243d75053 236 Pfam PF04519 Polymer-forming cytoskeletal 62 134 5.9E-8 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CSW12_RS13280 effe0efa52d5012732949da243d75053 236 Pfam PF04519 Polymer-forming cytoskeletal 45 120 7.7E-11 T 29-03-2018 IPR007607 Protein of unknown function DUF583 CSW12_RS13280 effe0efa52d5012732949da243d75053 236 Gene3D G3DSA:2.160.10.10 18 231 2.3E-5 T 29-03-2018 CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 368 2.3E-88 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 Gene3D G3DSA:3.40.1390.30 225 361 4.9E-23 T 29-03-2018 CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 Gene3D G3DSA:3.40.1390.30 6 128 4.5E-38 T 29-03-2018 CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 SUPERFAMILY SSF102705 6 372 6.28E-136 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 Gene3D G3DSA:3.30.70.120 134 224 3.5E-42 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 352 6.4E-85 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CSW12_RS21055 3b0a05c2a3495f2b63fa8caceb7c9f50 373 PIRSF PIRSF037489 4 373 3.7E-162 T 29-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.34 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 3.7E-62 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 8.0E-5 T 29-03-2018 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.6E-52 T 29-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 64 5.0E-18 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 Pfam PF01467 Cytidylyltransferase-like 9 134 1.1E-20 T 29-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 Gene3D G3DSA:3.40.50.620 2 159 2.3E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS08105 726da90d5b782a650819a3f454317b0e 163 SUPERFAMILY SSF52374 4 157 1.41E-44 T 29-03-2018 CSW12_RS15075 787716df9cfb3dc929e55d36e0e67500 33 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 1 24 2.1E-8 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS29150 356b7d871dbdc22818640163117f7b7b 235 Gene3D G3DSA:3.30.420.10 63 207 3.0E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29150 356b7d871dbdc22818640163117f7b7b 235 SUPERFAMILY SSF53098 72 191 6.07E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29150 356b7d871dbdc22818640163117f7b7b 235 Pfam PF13610 DDE domain 74 212 1.0E-49 T 29-03-2018 IPR032874 DDE domain CSW12_RS29640 356b7d871dbdc22818640163117f7b7b 235 Gene3D G3DSA:3.30.420.10 63 207 3.0E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29640 356b7d871dbdc22818640163117f7b7b 235 SUPERFAMILY SSF53098 72 191 6.07E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29640 356b7d871dbdc22818640163117f7b7b 235 Pfam PF13610 DDE domain 74 212 1.0E-49 T 29-03-2018 IPR032874 DDE domain CSW12_RS29680 356b7d871dbdc22818640163117f7b7b 235 Gene3D G3DSA:3.30.420.10 63 207 3.0E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29680 356b7d871dbdc22818640163117f7b7b 235 SUPERFAMILY SSF53098 72 191 6.07E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29680 356b7d871dbdc22818640163117f7b7b 235 Pfam PF13610 DDE domain 74 212 1.0E-49 T 29-03-2018 IPR032874 DDE domain CSW12_RS29415 356b7d871dbdc22818640163117f7b7b 235 Gene3D G3DSA:3.30.420.10 63 207 3.0E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29415 356b7d871dbdc22818640163117f7b7b 235 SUPERFAMILY SSF53098 72 191 6.07E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29415 356b7d871dbdc22818640163117f7b7b 235 Pfam PF13610 DDE domain 74 212 1.0E-49 T 29-03-2018 IPR032874 DDE domain CSW12_RS29110 356b7d871dbdc22818640163117f7b7b 235 Gene3D G3DSA:3.30.420.10 63 207 3.0E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29110 356b7d871dbdc22818640163117f7b7b 235 SUPERFAMILY SSF53098 72 191 6.07E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29110 356b7d871dbdc22818640163117f7b7b 235 Pfam PF13610 DDE domain 74 212 1.0E-49 T 29-03-2018 IPR032874 DDE domain CSW12_RS30100 356b7d871dbdc22818640163117f7b7b 235 Gene3D G3DSA:3.30.420.10 63 207 3.0E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS30100 356b7d871dbdc22818640163117f7b7b 235 SUPERFAMILY SSF53098 72 191 6.07E-9 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS30100 356b7d871dbdc22818640163117f7b7b 235 Pfam PF13610 DDE domain 74 212 1.0E-49 T 29-03-2018 IPR032874 DDE domain CSW12_RS26660 9cb54e229e77816aaf81babca9f5f366 169 Pfam PF08741 YwhD family 5 166 1.3E-85 T 29-03-2018 IPR014852 Uncharacterised protein YwhD CSW12_RS24295 37ff97a6b26f04c1e243bb180cc8aff0 396 Pfam PF00155 Aminotransferase class I and II 30 378 2.2E-71 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS24295 37ff97a6b26f04c1e243bb180cc8aff0 396 Gene3D G3DSA:3.90.1150.10 296 387 3.0E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS24295 37ff97a6b26f04c1e243bb180cc8aff0 396 Gene3D G3DSA:3.40.640.10 45 295 4.1E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS24295 37ff97a6b26f04c1e243bb180cc8aff0 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CSW12_RS24295 37ff97a6b26f04c1e243bb180cc8aff0 396 SUPERFAMILY SSF53383 7 385 8.74E-119 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS22145 ebb8954efa6292421d889ddee0f8f6d0 275 PIRSF PIRSF019271 1 275 1.3E-108 T 29-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 CSW12_RS22145 ebb8954efa6292421d889ddee0f8f6d0 275 Gene3D G3DSA:3.40.50.1000 47 212 8.6E-27 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS22145 ebb8954efa6292421d889ddee0f8f6d0 275 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 33 245 1.2E-48 T 29-03-2018 IPR005519 Acid phosphatase, class B-like CSW12_RS22145 ebb8954efa6292421d889ddee0f8f6d0 275 SUPERFAMILY SSF56784 58 250 7.6E-45 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS22145 ebb8954efa6292421d889ddee0f8f6d0 275 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 9 272 1.8E-93 T 29-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 CSW12_RS02240 5dbf67772f675c210559d7dc420b81d1 491 Pfam PF05709 Phage tail protein 17 491 9.5E-61 T 29-03-2018 IPR008841 Siphovirus-type tail component CSW12_RS02240 5dbf67772f675c210559d7dc420b81d1 491 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 4 126 1.6E-33 T 29-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal CSW12_RS01285 77b422d8ba8157d3fdb4757abf44bad6 144 Pfam PF01475 Ferric uptake regulator family 18 135 8.7E-41 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CSW12_RS01285 77b422d8ba8157d3fdb4757abf44bad6 144 SUPERFAMILY SSF46785 10 140 1.64E-43 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01285 77b422d8ba8157d3fdb4757abf44bad6 144 Gene3D G3DSA:1.10.10.10 2 90 2.4E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 261 274 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 516 533 3.2E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 533 553 3.2E-9 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 SMART SM00091 98 163 0.0025 T 29-03-2018 IPR000014 PAS domain CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Gene3D G3DSA:3.40.50.300 236 410 2.2E-26 T 29-03-2018 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 SUPERFAMILY SSF55785 94 201 1.14E-9 T 29-03-2018 IPR000014 PAS domain CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 SMART SM00382 257 401 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Pfam PF02954 Bacterial regulatory protein, Fis family 511 550 7.9E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 SUPERFAMILY SSF52540 239 480 1.78E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Gene3D G3DSA:3.30.450.20 90 224 2.5E-12 T 29-03-2018 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Pfam PF13596 PAS domain 103 201 1.9E-5 T 29-03-2018 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 324 339 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 SUPERFAMILY SSF46689 451 552 3.29E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 451 460 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Gene3D G3DSA:1.10.8.60 411 469 2.4E-21 T 29-03-2018 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Pfam PF00158 Sigma-54 interaction domain 238 404 1.1E-70 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS13500 e5c7ed42cb57922e3814adf86097cc27 553 Gene3D G3DSA:1.10.10.60 470 553 1.4E-16 T 29-03-2018 CSW12_RS12955 01f340271353cf4c300884f38bb852f1 223 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 183 4.1E-69 T 29-03-2018 IPR022301 Integral membrane protein YjbE CSW12_RS12955 01f340271353cf4c300884f38bb852f1 223 Pfam PF03741 Integral membrane protein TerC family 14 182 2.4E-45 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 68 148 2.4E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 SUPERFAMILY SSF53155 1 71 1.41E-17 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 Gene3D G3DSA:1.10.10.10 63 149 8.2E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 SUPERFAMILY SSF46767 66 148 6.8E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 5 147 40.544 T 29-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 63 1.8E-4 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 Gene3D G3DSA:3.30.160.70 1 62 3.3E-17 T 29-03-2018 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 117 123 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS17725 5fd16c13b848ab4120f5c49fc46d2e42 150 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 67 146 8.4E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS25075 45a844a16317ba144a5887953bed377e 168 SUPERFAMILY SSF47240 1 160 1.16E-58 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS25075 45a844a16317ba144a5887953bed377e 168 Gene3D G3DSA:1.20.1260.10 1 162 8.6E-44 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS25075 45a844a16317ba144a5887953bed377e 168 Pfam PF00210 Ferritin-like domain 8 144 1.1E-41 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 Pfam PF07687 Peptidase dimerisation domain 179 274 8.9E-13 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 Gene3D G3DSA:3.40.630.10 2 268 2.5E-64 T 29-03-2018 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 Gene3D G3DSA:3.40.630.10 269 380 1.7E-7 T 29-03-2018 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 SUPERFAMILY SSF55031 179 287 4.71E-31 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 SUPERFAMILY SSF53187 3 194 5.19E-82 T 29-03-2018 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 SUPERFAMILY SSF53187 295 377 5.19E-82 T 29-03-2018 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 12 364 1.3E-120 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 Pfam PF01546 Peptidase family M20/M25/M40 70 374 1.9E-33 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS09430 2a85a1199e242e938ef4e5361f47a219 381 PIRSF PIRSF005962 1 380 3.2E-129 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS24680 72bb48141a0b6c4e0832fa68ada6403f 243 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 17 231 3.1E-81 T 29-03-2018 IPR014197 Sporulation protein YunB CSW12_RS24680 72bb48141a0b6c4e0832fa68ada6403f 243 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 138 227 7.8E-30 T 29-03-2018 IPR014197 Sporulation protein YunB CSW12_RS24680 72bb48141a0b6c4e0832fa68ada6403f 243 PIRSF PIRSF021383 3 236 1.5E-65 T 29-03-2018 IPR014197 Sporulation protein YunB CSW12_RS13450 d1bd1c79942cd45d11f4af32f27135fa 393 PIRSF PIRSF021438 1 393 1.7E-165 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CSW12_RS13450 d1bd1c79942cd45d11f4af32f27135fa 393 SUPERFAMILY SSF52266 230 391 2.56E-17 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS13450 d1bd1c79942cd45d11f4af32f27135fa 393 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 7 390 1.8E-140 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CSW12_RS13450 d1bd1c79942cd45d11f4af32f27135fa 393 Pfam PF04914 DltD protein 41 391 1.9E-125 T 29-03-2018 IPR006998 DltD CSW12_RS13450 d1bd1c79942cd45d11f4af32f27135fa 393 Gene3D G3DSA:3.40.50.1110 67 392 9.0E-7 T 29-03-2018 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 29-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 SUPERFAMILY SSF100950 74 231 7.33E-36 T 29-03-2018 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 Gene3D G3DSA:1.10.10.10 5 80 8.3E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 Pfam PF00455 DeoR C terminal sensor domain 75 228 1.4E-46 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 SMART SM01134 73 231 2.5E-61 T 29-03-2018 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 Gene3D G3DSA:3.40.50.1360 81 241 1.1E-38 T 29-03-2018 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 SUPERFAMILY SSF46785 5 78 4.54E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.9E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.9E-8 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 SMART SM00420 6 58 3.6E-18 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS09200 3acad06e3780c797686761c9737e2654 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 5.4E-17 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 Gene3D G3DSA:3.40.50.300 35 352 4.8E-7 T 29-03-2018 CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 1.9E-93 T 29-03-2018 IPR010650 PrkA C-terminal domain CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 Pfam PF08298 PrkA AAA domain 22 369 6.7E-150 T 29-03-2018 IPR013153 PrkA AAA domain CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 PIRSF PIRSF000549 1 631 8.8E-266 T 29-03-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 SMART SM00763 21 371 3.9E-197 T 29-03-2018 IPR013153 PrkA AAA domain CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 SUPERFAMILY SSF52540 231 363 2.48E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 SUPERFAMILY SSF52540 405 459 2.48E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01450 5a7e5555a3dfd814c3a5b1e3a374b0a9 631 SUPERFAMILY SSF52540 67 178 2.48E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22255 ac82872975b233a6827cd9e496867519 167 Pfam PF05163 DinB family 1 159 2.7E-32 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CSW12_RS22255 ac82872975b233a6827cd9e496867519 167 SUPERFAMILY SSF109854 8 152 2.59E-32 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS22255 ac82872975b233a6827cd9e496867519 167 Gene3D G3DSA:1.20.120.450 1 150 1.3E-25 T 29-03-2018 CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 Gene3D G3DSA:3.30.700.10 7 97 3.0E-10 T 29-03-2018 CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 2.1E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 SUPERFAMILY SSF54523 7 82 8.63E-14 T 29-03-2018 CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 2.7E-6 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 PIRSF PIRSF029928 1 97 4.5E-34 T 29-03-2018 IPR016940 ComG operon protein C GO:0030420 CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 1.9E-10 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CSW12_RS20810 a13cdb2ead7922bf9e35dc420b224e45 99 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 1.9E-10 T 29-03-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CSW12_RS23280 1d5b5107fbdaa339da76978ef6961c24 139 Pfam PF13027 Protein of unknown function (DUF3888) 34 113 2.7E-14 T 29-03-2018 IPR024984 Protein of unknown function DUF3888 CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 Gene3D G3DSA:3.40.50.1000 1 28 0.05 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 93 194 1.3E-12 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 Gene3D G3DSA:1.10.150.240 29 92 3.5E-22 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 SUPERFAMILY SSF56784 3 229 8.13E-45 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 225 6.7E-84 T 29-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 Gene3D G3DSA:3.40.50.1000 93 231 2.2E-26 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26825 edb52a242ecd3766c6f2acad32f22d93 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 199 5.8E-23 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS28260 0395da6a38dfbc50746e19c61124bf4e 381 PIRSF PIRSF006078 1 378 3.1E-140 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CSW12_RS28260 0395da6a38dfbc50746e19c61124bf4e 381 Pfam PF02595 Glycerate kinase family 3 374 6.7E-148 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CSW12_RS28260 0395da6a38dfbc50746e19c61124bf4e 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 9.7E-157 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CSW12_RS28260 0395da6a38dfbc50746e19c61124bf4e 381 Gene3D G3DSA:3.90.1510.10 42 276 5.7E-92 T 29-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CSW12_RS28260 0395da6a38dfbc50746e19c61124bf4e 381 SUPERFAMILY SSF110738 2 375 1.83E-138 T 29-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CSW12_RS19985 61a3c4ca03785def2693a12e00d6f10e 224 PIRSF PIRSF000032 2 224 9.2E-103 T 29-03-2018 IPR023530 Cytochrome b6, PetB GO:0005506|GO:0016021|GO:0020037|GO:0022900|GO:0045158 CSW12_RS19985 61a3c4ca03785def2693a12e00d6f10e 224 Gene3D G3DSA:1.20.810.10 2 224 1.8E-76 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CSW12_RS19985 61a3c4ca03785def2693a12e00d6f10e 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 5.1E-49 T 29-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CSW12_RS19985 61a3c4ca03785def2693a12e00d6f10e 224 SUPERFAMILY SSF81342 6 224 1.01E-61 T 29-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 SMART SM00862 153 229 1.6E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 9.2E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 SUPERFAMILY SSF46894 130 230 4.76E-32 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 Gene3D G3DSA:1.10.10.10 127 235 3.0E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 Gene3D G3DSA:3.40.50.2300 2 126 1.1E-40 T 29-03-2018 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 Pfam PF00072 Response regulator receiver domain 6 115 9.4E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 SMART SM00448 4 114 1.7E-48 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS27175 9c39ac8ecead29d91cc71f14e8b27a47 235 SUPERFAMILY SSF52172 1 123 5.69E-45 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 234 16.897 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 9 219 1.7E-56 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 ProSitePatterns PS01218 TatC family signature. 147 166 - T 29-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 96 122 4.7E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 78 96 4.7E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 147 175 4.7E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 4.7E-35 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS16825 732158ca2acddb04298473b9f4271a81 246 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 214 8.9E-52 T 29-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 PIRSF PIRSF026583 1 657 1.6E-277 T 29-03-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Pfam PF02272 DHHA1 domain 518 644 2.1E-11 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Gene3D G3DSA:3.90.1640.10 317 536 1.0E-46 T 29-03-2018 CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Gene3D G3DSA:3.30.70.270 131 300 2.8E-6 T 29-03-2018 CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 SUPERFAMILY SSF64182 339 641 8.24E-70 T 29-03-2018 CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 SMART SM00267 132 299 3.4E-5 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS27215 07f0ce7a1fb4c7cc960fee3fcc38b9c8 657 Pfam PF01368 DHH family 339 496 1.9E-22 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Hamap MF_00195 GTPase Der [der]. 3 436 40.883 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 4.6E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 4.6E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:3.40.50.300 229 357 3.3E-18 T 29-03-2018 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.1E-24 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 6.2E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:3.30.300.20 358 434 7.1E-35 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 4.4E-179 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 9.6E-34 T 29-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 SUPERFAMILY SSF52540 5 167 6.97E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 SUPERFAMILY SSF52540 138 434 1.93E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:1.20.120.430 70 228 1.4E-43 T 29-03-2018 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 Gene3D G3DSA:1.20.120.430 2 69 1.2E-17 T 29-03-2018 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 PIRSF PIRSF006485 2 436 3.5E-172 T 29-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 175 339 2.3E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS07125 463d6d3a45a2b32202a1441d88569951 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 144 2.1E-23 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS17845 43542196252a210ce609070b5068d406 311 Pfam PF00248 Aldo/keto reductase family 15 309 3.2E-75 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17845 43542196252a210ce609070b5068d406 311 SUPERFAMILY SSF51430 1 309 1.23E-93 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17845 43542196252a210ce609070b5068d406 311 PRINTS PR00069 Aldo-keto reductase signature 44 68 2.1E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS17845 43542196252a210ce609070b5068d406 311 PRINTS PR00069 Aldo-keto reductase signature 109 127 2.1E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS17845 43542196252a210ce609070b5068d406 311 PRINTS PR00069 Aldo-keto reductase signature 174 203 2.1E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS17845 43542196252a210ce609070b5068d406 311 PRINTS PR00069 Aldo-keto reductase signature 140 157 2.1E-11 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS17845 43542196252a210ce609070b5068d406 311 Gene3D G3DSA:3.20.20.100 1 311 5.9E-94 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17630 e10ce7bab73bc3371eef7b1a139d3ce4 207 Pfam PF13460 NAD(P)H-binding 7 193 5.4E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS17630 e10ce7bab73bc3371eef7b1a139d3ce4 207 Gene3D G3DSA:3.40.50.720 1 207 1.8E-21 T 29-03-2018 CSW12_RS17630 e10ce7bab73bc3371eef7b1a139d3ce4 207 SUPERFAMILY SSF51735 1 204 1.73E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01965 d7582cbd1869fd1536d683ec050b78db 415 Gene3D G3DSA:3.40.190.10 1 379 0.0013 T 29-03-2018 CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 SUPERFAMILY SSF55186 100 240 1.03E-34 T 29-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 Gene3D G3DSA:3.30.980.10 97 251 4.6E-31 T 29-03-2018 CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 Pfam PF01411 tRNA synthetases class II (A) 29 86 3.0E-8 T 29-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 SMART SM00863 192 234 4.6E-9 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 SUPERFAMILY SSF50447 14 92 6.71E-17 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 Pfam PF02272 DHHA1 domain 271 403 3.6E-12 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CSW12_RS09635 e5f0bd72c79ca871dc2ba5b9d3cd12ae 411 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 192 232 5.5E-8 T 29-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 29-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 SMART SM00829 9 335 8.3E-8 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 SUPERFAMILY SSF51735 137 305 9.07E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 Gene3D G3DSA:3.90.180.10 1 146 9.3E-46 T 29-03-2018 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 Pfam PF00107 Zinc-binding dehydrogenase 174 297 2.0E-23 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 133 1.9E-29 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 Gene3D G3DSA:3.40.50.720 147 330 1.0E-31 T 29-03-2018 CSW12_RS16635 907a7d9976e2404ce700e020491245d0 345 SUPERFAMILY SSF50129 1 179 9.74E-48 T 29-03-2018 IPR011032 GroES-like CSW12_RS16950 f4742c2236208f5b94708fcd393dc193 265 Pfam PF10997 Alternate to MurJ 11 260 5.7E-93 T 29-03-2018 IPR021260 Lipid II flippase Amj CSW12_RS16950 f4742c2236208f5b94708fcd393dc193 265 Hamap MF_02077 Lipid II flippase Amj [amj]. 2 262 25.648 T 29-03-2018 IPR021260 Lipid II flippase Amj CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 TIGRFAM TIGR01441 GPR: GPR endopeptidase 10 367 4.1E-184 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 SUPERFAMILY SSF53163 3 367 9.68E-132 T 29-03-2018 IPR023430 Peptidase HybD-like domain CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 PIRSF PIRSF019549 3 367 4.8E-190 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 Gene3D G3DSA:3.40.50.1450 8 363 6.1E-130 T 29-03-2018 IPR023430 Peptidase HybD-like domain CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 Hamap MF_00626 Germination protease [gpr]. 1 367 167.035 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 Pfam PF03418 Germination protease 17 366 1.0E-194 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CSW12_RS21225 275177e2647a9e01701f97f9f2470fd5 367 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 10 367 0.0 T 29-03-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 CSW12_RS02580 293ff321099f0374c10e31bff6a2bc28 273 Gene3D G3DSA:1.10.10.10 8 97 2.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02580 293ff321099f0374c10e31bff6a2bc28 273 SUPERFAMILY SSF46785 22 96 6.58E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22185 5ff55492d2a7ae7643a61bdaded4a901 208 Gene3D G3DSA:1.20.1300.10 2 208 1.5E-45 T 29-03-2018 CSW12_RS22185 5ff55492d2a7ae7643a61bdaded4a901 208 SUPERFAMILY SSF81343 4 203 7.85E-63 T 29-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22185 5ff55492d2a7ae7643a61bdaded4a901 208 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 190 1.3E-12 T 29-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22185 5ff55492d2a7ae7643a61bdaded4a901 208 PIRSF PIRSF000170 1 204 6.8E-105 T 29-03-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute CSW12_RS22185 5ff55492d2a7ae7643a61bdaded4a901 208 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 5 200 1.7E-55 T 29-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 21 385 8.1E-176 T 29-03-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 SMART SM00835 57 198 7.3E-16 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 SMART SM00835 234 375 4.2E-30 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 89 168 2.0E-4 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 Pfam PF00190 Cupin 65 192 9.2E-20 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 Pfam PF00190 Cupin 235 370 8.3E-24 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 SUPERFAMILY SSF51182 26 384 4.53E-102 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 Gene3D G3DSA:2.60.120.10 215 388 4.2E-40 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS04445 a7c70608f2503410ec460f043c36dff6 398 Gene3D G3DSA:2.60.120.10 8 214 2.5E-44 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS20845 743c870cb2ac02e2a220af0bd91708f2 80 Pfam PF13051 Protein of unknown function (DUF3912) 11 78 9.6E-45 T 29-03-2018 IPR025023 Protein of unknown function DUF3912 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Gene3D G3DSA:3.40.50.970 369 574 1.5E-30 T 29-03-2018 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Gene3D G3DSA:3.40.50.1220 209 368 4.2E-26 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 13 446 3.9E-153 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 5 571 35.883 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 438 553 2.2E-10 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Pfam PF16582 Middle domain of thiamine pyrophosphate 222 403 1.7E-17 T 29-03-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Gene3D G3DSA:3.40.50.970 11 191 3.6E-51 T 29-03-2018 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 176 4.6E-37 T 29-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 PIRSF PIRSF004983 2 578 2.1E-216 T 29-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 SUPERFAMILY SSF52518 14 180 2.7E-34 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 SUPERFAMILY SSF52467 168 373 1.72E-7 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS24025 b129e0827fcb30beac11462b7f9e0eba 584 SUPERFAMILY SSF52518 387 575 2.49E-32 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS01280 90c436f0e88c9d81211705ad1a3c8265 151 PIRSF PIRSF000239 1 150 7.9E-29 T 29-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS01280 90c436f0e88c9d81211705ad1a3c8265 151 Pfam PF00578 AhpC/TSA family 4 131 1.0E-40 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS01280 90c436f0e88c9d81211705ad1a3c8265 151 Gene3D G3DSA:3.40.30.10 1 151 2.0E-41 T 29-03-2018 CSW12_RS01280 90c436f0e88c9d81211705ad1a3c8265 151 SUPERFAMILY SSF52833 1 151 1.47E-55 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 Pfam PF08245 Mur ligase middle domain 47 273 3.2E-12 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 SUPERFAMILY SSF53623 3 299 1.22E-94 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 SUPERFAMILY SSF53244 301 431 1.47E-30 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 Gene3D G3DSA:3.90.190.20 301 433 6.1E-29 T 29-03-2018 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 PIRSF PIRSF001563 1 433 3.2E-156 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 Gene3D G3DSA:3.40.1190.10 3 299 4.0E-79 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 428 8.0E-127 T 29-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 373 2.7E-11 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS21920 5be40b321f0debafdc23b9dbf617ca2b 433 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 29-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CSW12_RS18625 aade8a1d700bc857f33ac72d7cb24044 193 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 6 165 36.286 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS18625 aade8a1d700bc857f33ac72d7cb24044 193 Pfam PF01625 Peptide methionine sulfoxide reductase 9 159 2.8E-59 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS18625 aade8a1d700bc857f33ac72d7cb24044 193 Gene3D G3DSA:3.30.1060.10 1 174 4.7E-66 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS18625 aade8a1d700bc857f33ac72d7cb24044 193 SUPERFAMILY SSF55068 4 166 2.62E-70 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS18625 aade8a1d700bc857f33ac72d7cb24044 193 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 158 1.6E-62 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.4E-97 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 Pfam PF00162 Phosphoglycerate kinase 6 383 9.8E-167 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 Gene3D G3DSA:3.40.50.1260 3 178 1.8E-77 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 SUPERFAMILY SSF53748 1 393 6.83E-164 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 PIRSF PIRSF000724 1 394 1.0E-159 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.2 T 29-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 Gene3D G3DSA:3.40.50.1260 179 381 2.9E-86 T 29-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25355 2413fed2538b5e6d7d3cea0942543783 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 29-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 SUPERFAMILY SSF51261 25 149 5.75E-42 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 Gene3D G3DSA:3.10.350.10 160 204 1.4E-12 T 29-03-2018 CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 SMART SM00257 161 204 1.9E-10 T 29-03-2018 IPR018392 LysM domain CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 Pfam PF01551 Peptidase family M23 46 139 1.3E-28 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 SUPERFAMILY SSF54106 161 203 1.7E-10 T 29-03-2018 IPR018392 LysM domain CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 Gene3D G3DSA:2.70.70.10 18 152 3.0E-39 T 29-03-2018 CSW12_RS06985 99433bb7d9db3fd2ba48070676068f83 204 Pfam PF01476 LysM domain 162 203 8.8E-13 T 29-03-2018 IPR018392 LysM domain CSW12_RS25430 7a5b97843eb767a08f4ead31eddb399b 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 6.5E-51 T 29-03-2018 IPR014204 Sporulation stage V, protein AE CSW12_RS25430 7a5b97843eb767a08f4ead31eddb399b 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 110 8.4E-40 T 29-03-2018 IPR005562 SpoVA CSW12_RS10450 58f32514cd21e7d780c8ade3ca89ed82 385 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 49 381 2.7E-91 T 29-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CSW12_RS10450 58f32514cd21e7d780c8ade3ca89ed82 385 SUPERFAMILY SSF55909 43 381 6.25E-100 T 29-03-2018 CSW12_RS10450 58f32514cd21e7d780c8ade3ca89ed82 385 Gene3D G3DSA:3.75.10.10 35 384 2.8E-105 T 29-03-2018 CSW12_RS02365 60480cc273207330fafac7d4ab47b2e8 111 Pfam PF12844 Helix-turn-helix domain 5 65 1.5E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02365 60480cc273207330fafac7d4ab47b2e8 111 SUPERFAMILY SSF47413 1 68 1.96E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02365 60480cc273207330fafac7d4ab47b2e8 111 SMART SM00530 7 62 4.9E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02365 60480cc273207330fafac7d4ab47b2e8 111 Gene3D G3DSA:1.10.3100.10 1 111 3.6E-25 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 SUPERFAMILY SSF51735 3 160 7.12E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 Gene3D G3DSA:3.40.50.720 3 173 3.6E-16 T 29-03-2018 CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 Gene3D G3DSA:1.10.1040.10 174 296 1.3E-31 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 SUPERFAMILY SSF48179 174 294 3.4E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 175 293 4.0E-30 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 147 3.1E-29 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CSW12_RS08155 6de1d03a9e272c6cead83360b9896939 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 4 294 2.8E-72 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:3.30.450.20 35 184 3.4E-10 T 29-03-2018 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 495 604 4.6E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF00672 HAMP domain 211 259 1.8E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF158472 211 259 2.09E-10 T 29-03-2018 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 382 1.6E-6 T 29-03-2018 IPR000014 PAS domain CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF47384 368 448 1.2E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00388 382 449 6.2E-20 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00304 210 262 2.9E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF55874 438 608 2.75E-49 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF00989 PAS fold 271 319 6.6E-8 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 584 1.1E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 545 1.1E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 590 603 1.1E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 559 1.1E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:3.30.450.20 251 383 8.0E-20 T 29-03-2018 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:1.10.287.130 384 445 1.2E-17 T 29-03-2018 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Gene3D G3DSA:3.30.565.10 453 613 3.2E-47 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00091 269 335 6.2E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SUPERFAMILY SSF55785 257 374 2.62E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 Pfam PF00512 His Kinase A (phospho-acceptor) domain 383 448 6.9E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27170 9d151ff160d221b4c39e36116d0b1946 613 SMART SM00387 494 606 4.0E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 161 182 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 Gene3D G3DSA:1.10.4030.10 25 123 3.6E-5 T 29-03-2018 CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 SUPERFAMILY SSF54534 128 222 2.88E-31 T 29-03-2018 CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 Pfam PF13616 PPIC-type PPIASE domain 130 224 1.5E-27 T 29-03-2018 CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 Gene3D G3DSA:3.10.50.40 124 246 5.9E-38 T 29-03-2018 CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 SUPERFAMILY SSF109998 43 162 1.06E-12 T 29-03-2018 IPR027304 Trigger factor/SurA domain CSW12_RS16365 19db50204ebc901557b67859ad2b459c 283 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 281 21.78 T 29-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CSW12_RS05655 2019959b740047112bfa27db75a6fbf3 167 Gene3D G3DSA:2.60.120.40 18 167 4.8E-19 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 Gene3D G3DSA:3.40.50.2300 1 144 1.1E-43 T 29-03-2018 CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 SMART SM00226 2 142 4.5E-40 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 41 57 6.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 6.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 114 129 6.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 74 89 6.4E-10 T 29-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 SUPERFAMILY SSF52788 1 142 1.83E-42 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS26380 f184d1b1c0906bb0824067c673b9ac5c 146 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 140 7.8E-34 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS27015 3e05a9c1a25d38115c7a17052df42690 297 Gene3D G3DSA:3.40.50.720 6 297 5.5E-28 T 29-03-2018 CSW12_RS27015 3e05a9c1a25d38115c7a17052df42690 297 SUPERFAMILY SSF51735 9 293 4.8E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS27015 3e05a9c1a25d38115c7a17052df42690 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 186 6.2E-8 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 218 301 1.5E-16 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 SMART SM00833 218 303 1.1E-19 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 SUPERFAMILY SSF52540 2 208 3.06E-27 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 Gene3D G3DSA:3.30.1220.10 199 304 1.3E-15 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 SUPERFAMILY SSF90002 218 301 1.01E-14 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 Gene3D G3DSA:3.40.50.300 1 198 8.7E-35 T 29-03-2018 CSW12_RS18215 1ceb415ce20817bc7ab19fd3d7cbeea6 307 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 184 1.5E-44 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 Gene3D G3DSA:1.10.10.60 2 47 2.3E-13 T 29-03-2018 CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 SUPERFAMILY SSF48498 124 206 1.0E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 7.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 7.9E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 Gene3D G3DSA:1.10.357.10 89 208 4.0E-6 T 29-03-2018 CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 SUPERFAMILY SSF46689 13 98 4.41E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 Gene3D G3DSA:1.10.260.40 48 88 5.5E-10 T 29-03-2018 CSW12_RS16010 9b3ebbbeba45ded17afe5ebea46cc1af 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 9.2E-14 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 Pfam PF07694 5TMR of 5TMR-LYT 19 164 1.3E-11 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 378 3.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 397 3.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 359 3.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 345 3.2E-14 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 SMART SM00388 186 252 1.8E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 SUPERFAMILY SSF47384 182 250 5.3E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 398 8.1E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 SUPERFAMILY SSF55874 244 398 4.19E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 SMART SM00387 294 400 2.6E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 Gene3D G3DSA:1.10.287.130 165 248 4.2E-13 T 29-03-2018 CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 Gene3D G3DSA:3.30.565.10 252 402 2.4E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06245 a49c8ce36bceb3d2f0d5374c70580845 402 Pfam PF00512 His Kinase A (phospho-acceptor) domain 188 248 1.8E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Pfam PF00817 impB/mucB/samB family 15 162 1.0E-49 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 SUPERFAMILY SSF100879 249 349 4.24E-24 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 SUPERFAMILY SSF56672 6 242 1.16E-80 T 29-03-2018 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Pfam PF11799 impB/mucB/samB family C-terminal domain 249 351 1.2E-17 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Hamap MF_01113 DNA polymerase IV [dinB]. 9 361 37.201 T 29-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Gene3D G3DSA:1.10.150.20 179 252 6.3E-18 T 29-03-2018 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Gene3D G3DSA:3.30.1490.100 253 357 1.0E-24 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Pfam PF11798 IMS family HHH motif 176 205 1.5E-7 T 29-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Gene3D G3DSA:3.30.70.270 123 178 5.1E-16 T 29-03-2018 CSW12_RS20285 4be3cb163b4422477731380eb8382641 412 Gene3D G3DSA:3.30.70.270 50 122 3.0E-25 T 29-03-2018 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 Gene3D G3DSA:3.30.70.580 1 106 1.1E-31 T 29-03-2018 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 Pfam PF01416 tRNA pseudouridine synthase 9 105 3.9E-9 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 Pfam PF01416 tRNA pseudouridine synthase 144 245 5.4E-27 T 29-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 SUPERFAMILY SSF55120 1 245 1.04E-77 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 245 35.679 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 240 9.4E-63 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 PIRSF PIRSF001430 1 245 1.1E-80 T 29-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS01040 03d13e4a2e3747cf5165be1619943f4e 245 Gene3D G3DSA:3.30.70.660 107 244 1.6E-39 T 29-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 Gene3D G3DSA:3.40.50.10860 47 181 1.7E-50 T 29-03-2018 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 SUPERFAMILY SSF53223 18 197 4.8E-66 T 29-03-2018 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 Gene3D G3DSA:3.40.50.720 195 428 2.7E-79 T 29-03-2018 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 114 127 - T 29-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 SUPERFAMILY SSF51735 195 427 5.49E-80 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 106 120 3.8E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 228 248 3.8E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 186 208 3.8E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 3.8E-30 T 29-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 SMART SM00839 197 426 3.0E-98 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 PIRSF PIRSF000185 7 428 1.3E-176 T 29-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 51 177 2.1E-54 T 29-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS07045 3d8d7a55be670b7445597d9c677d0ada 428 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 195 426 1.2E-79 T 29-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CSW12_RS15515 05c875b34a213679b315d3671e5f72c9 240 Gene3D G3DSA:3.40.50.1820 2 233 1.7E-28 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS15515 05c875b34a213679b315d3671e5f72c9 240 Pfam PF00975 Thioesterase domain 5 228 3.1E-47 T 29-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CSW12_RS15515 05c875b34a213679b315d3671e5f72c9 240 SUPERFAMILY SSF53474 3 228 2.63E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS21715 6d6890fcda5caeafeaca62b5b49953f9 127 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 2.7E-25 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CSW12_RS21715 6d6890fcda5caeafeaca62b5b49953f9 127 Pfam PF12670 Protein of unknown function (DUF3792) 10 119 1.6E-18 T 29-03-2018 IPR023804 Protein of unknown function DUF3792, transmembrane CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.378 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 6.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 6.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 6.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 6.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 6.1E-32 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 2.8E-183 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 PIRSF PIRSF001529 1 424 7.6E-193 T 29-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 Gene3D G3DSA:1.10.287.40 2 105 2.0E-27 T 29-03-2018 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 SUPERFAMILY SSF55681 117 423 9.52E-108 T 29-03-2018 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 1.1E-39 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 SUPERFAMILY SSF46589 1 113 1.36E-31 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.8E-33 T 29-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CSW12_RS27390 3c19e1caac959f01bdcfe20d8992468b 424 Gene3D G3DSA:3.30.930.10 106 424 2.1E-103 T 29-03-2018 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 5.9E-21 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-9 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 Gene3D G3DSA:3.40.190.10 88 179 2.6E-24 T 29-03-2018 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 SUPERFAMILY SSF46785 1 111 7.72E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 Pfam PF03466 LysR substrate binding domain 89 289 3.4E-45 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 SUPERFAMILY SSF53850 90 294 3.19E-44 T 29-03-2018 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 Gene3D G3DSA:3.40.190.10 180 267 9.7E-20 T 29-03-2018 CSW12_RS25570 f13fdf16080bcab30a3a4d435f9c3255 297 Gene3D G3DSA:1.10.10.10 1 83 3.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17250 05ebf0cd5f3f93667836b7c8fc1125aa 156 SUPERFAMILY SSF54690 4 139 1.06E-46 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS17250 05ebf0cd5f3f93667836b7c8fc1125aa 156 Gene3D G3DSA:3.90.1170.40 1 140 5.5E-47 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS17250 05ebf0cd5f3f93667836b7c8fc1125aa 156 Pfam PF02391 MoaE protein 10 119 1.7E-35 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS04525 32fd965362aa6621fe2c41b9e107a9e2 185 Gene3D G3DSA:1.10.10.10 1 167 1.0E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04525 32fd965362aa6621fe2c41b9e107a9e2 185 SMART SM00347 37 137 1.5E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS04525 32fd965362aa6621fe2c41b9e107a9e2 185 Pfam PF01047 MarR family 44 101 1.2E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS04525 32fd965362aa6621fe2c41b9e107a9e2 185 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 2 185 49.756 T 29-03-2018 IPR023488 HTH-type transcriptional regulator Hpr CSW12_RS04525 32fd965362aa6621fe2c41b9e107a9e2 185 SUPERFAMILY SSF46785 19 130 4.07E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04525 32fd965362aa6621fe2c41b9e107a9e2 185 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CSW12_RS14930 25cd147e99b23e7698a80d7d3b5f36b5 282 SUPERFAMILY SSF55729 182 272 1.01E-8 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS14930 25cd147e99b23e7698a80d7d3b5f36b5 282 SUPERFAMILY SSF55729 1 208 1.01E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS14930 25cd147e99b23e7698a80d7d3b5f36b5 282 Pfam PF00583 Acetyltransferase (GNAT) family 41 134 2.5E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS14930 25cd147e99b23e7698a80d7d3b5f36b5 282 Pfam PF13673 Acetyltransferase (GNAT) domain 172 246 1.1E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS14930 25cd147e99b23e7698a80d7d3b5f36b5 282 Gene3D G3DSA:3.40.630.30 2 144 1.8E-19 T 29-03-2018 CSW12_RS14930 25cd147e99b23e7698a80d7d3b5f36b5 282 Gene3D G3DSA:3.40.630.30 145 279 9.9E-13 T 29-03-2018 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 Gene3D G3DSA:3.30.2140.10 3 131 3.7E-24 T 29-03-2018 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 6.3E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 6.3E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 6.3E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 261 274 6.3E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 6.3E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 Gene3D G3DSA:3.30.2140.10 132 278 1.2E-7 T 29-03-2018 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 Pfam PF00797 N-acetyltransferase 22 268 1.6E-43 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS17175 143c838e48952b48b3842b97af5a561b 279 SUPERFAMILY SSF54001 1 275 6.87E-62 T 29-03-2018 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Gene3D G3DSA:3.40.50.620 249 368 7.0E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 538 38.764 T 29-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Pfam PF08264 Anticodon-binding domain of tRNA 416 511 4.2E-9 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 SUPERFAMILY SSF47323 385 540 3.18E-38 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 528 9.7E-158 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 SUPERFAMILY SSF52374 170 380 1.91E-92 T 29-03-2018 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 SUPERFAMILY SSF52374 4 136 1.91E-92 T 29-03-2018 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 SUPERFAMILY SSF57770 137 170 3.92E-8 T 29-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Gene3D G3DSA:3.40.50.620 3 142 3.6E-22 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 2.9E-19 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 85 96 2.9E-19 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 2.9E-19 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 287 302 2.9E-19 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 380 391 2.9E-19 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 2.9E-19 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Pfam PF09334 tRNA synthetases class I (M) 4 393 3.4E-139 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Gene3D G3DSA:2.20.28.20 143 159 1.1E-10 T 29-03-2018 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Gene3D G3DSA:2.170.220.10 160 248 2.5E-14 T 29-03-2018 CSW12_RS24980 b7296f87fa890a479f01204931caf623 544 Gene3D G3DSA:1.10.730.10 369 529 4.6E-35 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 Gene3D G3DSA:3.10.580.10 195 344 6.8E-32 T 29-03-2018 CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 SUPERFAMILY SSF54631 204 341 1.52E-30 T 29-03-2018 CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 Gene3D G3DSA:3.30.465.10 345 431 2.5E-23 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 Pfam PF00571 CBS domain 288 338 5.1E-7 T 29-03-2018 IPR000644 CBS domain CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 SUPERFAMILY SSF56176 352 437 3.82E-19 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 Pfam PF03471 Transporter associated domain 356 429 1.2E-18 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 SMART SM01091 354 431 2.5E-22 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS11105 3e130aa0ce6f63e645ac91d23605f67a 442 Pfam PF01595 Domain of unknown function DUF21 9 201 2.5E-50 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 Gene3D G3DSA:3.30.70.260 256 336 1.5E-22 T 29-03-2018 CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 SUPERFAMILY SSF55021 252 332 4.12E-20 T 29-03-2018 CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 SUPERFAMILY SSF52540 1 240 1.08E-86 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 SMART SM00382 30 226 4.6E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 Gene3D G3DSA:3.40.50.300 1 255 8.6E-80 T 29-03-2018 CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 Pfam PF00005 ABC transporter 22 169 1.6E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 Pfam PF09383 NIL domain 263 326 2.5E-19 T 29-03-2018 IPR018449 NIL domain CSW12_RS00150 4442cea083a5b8ab8a08e609d695456f 339 SMART SM00930 260 334 7.4E-27 T 29-03-2018 IPR018449 NIL domain CSW12_RS21875 a4f7623525e39e245e563427c37396dd 265 Gene3D G3DSA:3.40.50.300 2 251 2.5E-59 T 29-03-2018 CSW12_RS21875 a4f7623525e39e245e563427c37396dd 265 SUPERFAMILY SSF52540 5 258 8.52E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21875 a4f7623525e39e245e563427c37396dd 265 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 218 2.9E-26 T 29-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CSW12_RS21875 a4f7623525e39e245e563427c37396dd 265 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 262 1.2E-122 T 29-03-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CSW12_RS21875 a4f7623525e39e245e563427c37396dd 265 PIRSF PIRSF003092 1 265 4.2E-93 T 29-03-2018 IPR025501 ATP binding protein MinD CSW12_RS22055 2c27a8dd54ba44ddaf464d91a9627f21 205 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 197 8.1E-62 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CSW12_RS22055 2c27a8dd54ba44ddaf464d91a9627f21 205 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 5 200 49.279 T 29-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CSW12_RS22055 2c27a8dd54ba44ddaf464d91a9627f21 205 Pfam PF01725 Ham1 family 7 196 6.4E-59 T 29-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CSW12_RS22055 2c27a8dd54ba44ddaf464d91a9627f21 205 SUPERFAMILY SSF52972 3 199 6.28E-71 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CSW12_RS22055 2c27a8dd54ba44ddaf464d91a9627f21 205 Gene3D G3DSA:3.90.950.10 1 201 4.4E-78 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CSW12_RS27250 657da29b95f6e9531036051893f057b0 293 SUPERFAMILY SSF50182 120 182 3.92E-15 T 29-03-2018 IPR010920 LSM domain CSW12_RS27250 657da29b95f6e9531036051893f057b0 293 Pfam PF00924 Mechanosensitive ion channel 77 274 6.5E-46 T 29-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CSW12_RS27250 657da29b95f6e9531036051893f057b0 293 SUPERFAMILY SSF82689 186 284 2.88E-17 T 29-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CSW12_RS27250 657da29b95f6e9531036051893f057b0 293 Gene3D G3DSA:3.30.70.100 185 279 2.4E-16 T 29-03-2018 CSW12_RS27250 657da29b95f6e9531036051893f057b0 293 SUPERFAMILY SSF82861 30 118 5.75E-14 T 29-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CSW12_RS27250 657da29b95f6e9531036051893f057b0 293 Gene3D G3DSA:2.30.30.60 135 184 1.9E-14 T 29-03-2018 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 Gene3D G3DSA:2.30.42.10 307 413 6.8E-23 T 29-03-2018 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 SUPERFAMILY SSF50156 288 403 5.78E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 SUPERFAMILY SSF50494 84 304 1.56E-58 T 29-03-2018 IPR009003 Peptidase S1, PA clan CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 SMART SM00228 307 395 1.7E-7 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 Pfam PF13180 PDZ domain 307 400 4.7E-17 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 PRINTS PR00834 HtrA/DegQ protease family signature 136 148 1.8E-43 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 PRINTS PR00834 HtrA/DegQ protease family signature 157 177 1.8E-43 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 1.8E-43 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 PRINTS PR00834 HtrA/DegQ protease family signature 262 279 1.8E-43 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 PRINTS PR00834 HtrA/DegQ protease family signature 352 364 1.8E-43 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 PRINTS PR00834 HtrA/DegQ protease family signature 198 222 1.8E-43 T 29-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 Gene3D G3DSA:2.40.10.10 67 198 3.0E-28 T 29-03-2018 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 Pfam PF13365 Trypsin-like peptidase domain 124 269 1.9E-31 T 29-03-2018 CSW12_RS09745 2e8e48776064ecd6ed7f6c7b2ff4522e 413 Gene3D G3DSA:2.40.10.10 199 306 1.4E-36 T 29-03-2018 CSW12_RS10420 58fc64d2ef5b57cc1a90c61f8573c8c2 314 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 305 1.3E-50 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CSW12_RS10420 58fc64d2ef5b57cc1a90c61f8573c8c2 314 SUPERFAMILY SSF51695 36 311 1.33E-73 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS10420 58fc64d2ef5b57cc1a90c61f8573c8c2 314 Gene3D G3DSA:3.20.20.190 19 314 2.7E-80 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS21285 a753dc6ee226bcfb32b450f7ea91cdaf 192 Gene3D G3DSA:1.10.3210.10 2 190 3.7E-30 T 29-03-2018 CSW12_RS21285 a753dc6ee226bcfb32b450f7ea91cdaf 192 Pfam PF01966 HD domain 21 133 4.9E-15 T 29-03-2018 IPR006674 HD domain CSW12_RS21285 a753dc6ee226bcfb32b450f7ea91cdaf 192 SUPERFAMILY SSF109604 10 184 4.28E-37 T 29-03-2018 CSW12_RS21285 a753dc6ee226bcfb32b450f7ea91cdaf 192 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 13 183 2.1E-62 T 29-03-2018 IPR005249 Conserved hypothetical protein CHP00488 CSW12_RS21285 a753dc6ee226bcfb32b450f7ea91cdaf 192 SMART SM00471 17 144 4.2E-9 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS21285 a753dc6ee226bcfb32b450f7ea91cdaf 192 TIGRFAM TIGR00277 HDIG: HDIG domain 18 97 5.0E-8 T 29-03-2018 IPR006675 HDIG domain CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 SUPERFAMILY SSF103473 475 500 2.35E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 SUPERFAMILY SSF103473 271 442 2.35E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 SUPERFAMILY SSF103473 27 219 2.35E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 34 467 4.4E-121 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 Gene3D G3DSA:1.20.1250.20 282 510 3.0E-29 T 29-03-2018 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 130 150 8.3E-11 T 29-03-2018 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 38 62 8.3E-11 T 29-03-2018 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 160 184 8.3E-11 T 29-03-2018 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 PRINTS PR01036 Tetracycline resistance protein TetB signature 325 349 8.3E-11 T 29-03-2018 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 Gene3D G3DSA:1.20.1250.20 29 224 1.1E-29 T 29-03-2018 CSW12_RS11715 fb45de97a417d9504a97b7ad9fa5c389 513 Pfam PF07690 Major Facilitator Superfamily 39 432 3.6E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 Hamap MF_00109 Shikimate kinase [aroK]. 1 164 25.624 T 29-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 Gene3D G3DSA:3.40.50.300 2 165 8.9E-31 T 29-03-2018 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 Pfam PF01202 Shikimate kinase 10 163 2.1E-48 T 29-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 PRINTS PR01100 Shikimate kinase family signature 4 19 1.5E-21 T 29-03-2018 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 PRINTS PR01100 Shikimate kinase family signature 28 41 1.5E-21 T 29-03-2018 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 PRINTS PR01100 Shikimate kinase family signature 94 111 1.5E-21 T 29-03-2018 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 PRINTS PR01100 Shikimate kinase family signature 56 64 1.5E-21 T 29-03-2018 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 PRINTS PR01100 Shikimate kinase family signature 73 82 1.5E-21 T 29-03-2018 CSW12_RS20770 35e38c2e7c7ad3d0330ce9646bdc5d0f 165 SUPERFAMILY SSF52540 3 160 8.02E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 237 247 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Pfam PF00082 Subtilase family 195 583 6.5E-64 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Pfam PF13860 FlgD Ig-like domain 764 800 3.8E-7 T 29-03-2018 IPR025965 FlgD Ig-like domain CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Gene3D G3DSA:2.60.40.10 813 915 2.4E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 200 211 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 5.4E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 214 5.4E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 PRINTS PR00723 Subtilisin serine protease family (S8) signature 528 544 5.4E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Pfam PF05922 Peptidase inhibitor I9 64 158 8.6E-10 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 529 539 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 SUPERFAMILY SSF52025 382 448 3.27E-14 T 29-03-2018 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 SUPERFAMILY SSF52743 490 592 5.37E-87 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 SUPERFAMILY SSF52743 172 356 5.37E-87 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Gene3D G3DSA:2.60.40.1710 595 698 8.0E-7 T 29-03-2018 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Gene3D G3DSA:3.30.70.80 54 156 3.2E-11 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Gene3D G3DSA:3.40.50.200 157 594 2.7E-92 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS21410 7f7d71339404dc665cb3b3232d2aed8b 915 Pfam PF02225 PA domain 385 467 1.8E-10 T 29-03-2018 IPR003137 PA domain CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 SUPERFAMILY SSF52540 183 433 6.2E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 SUPERFAMILY SSF48024 8 119 4.97E-38 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 2.9E-35 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 5.6E-118 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 442 3.7E-187 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 Gene3D G3DSA:3.40.50.300 167 448 8.8E-79 T 29-03-2018 CSW12_RS27205 c2c0264a1627642248aa3b927ab26957 449 Gene3D G3DSA:1.10.860.10 2 151 1.4E-49 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CSW12_RS16530 af9b72ad6aa5d31ad7171092ddfa7749 474 SUPERFAMILY SSF53720 3 473 2.36E-151 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS16530 af9b72ad6aa5d31ad7171092ddfa7749 474 Pfam PF00171 Aldehyde dehydrogenase family 18 470 2.6E-160 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS16530 af9b72ad6aa5d31ad7171092ddfa7749 474 Gene3D G3DSA:3.40.309.10 263 456 1.2E-61 T 29-03-2018 CSW12_RS16530 af9b72ad6aa5d31ad7171092ddfa7749 474 Gene3D G3DSA:3.40.605.10 1 262 3.0E-85 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS12770 f73f70634c325e1eff5453068681bef7 111 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 81 3.0E-15 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CSW12_RS12770 f73f70634c325e1eff5453068681bef7 111 SUPERFAMILY SSF54909 4 102 9.39E-23 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS12770 f73f70634c325e1eff5453068681bef7 111 Gene3D G3DSA:3.30.70.100 1 111 1.7E-24 T 29-03-2018 CSW12_RS20150 ba10a732294b14ef00c13164bc608dd5 118 Gene3D G3DSA:1.20.1270.30 5 83 2.0E-6 T 29-03-2018 CSW12_RS20150 ba10a732294b14ef00c13164bc608dd5 118 Gene3D G3DSA:1.20.1270.30 84 117 0.0035 T 29-03-2018 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 Gene3D G3DSA:1.10.10.10 279 371 2.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 PRINTS PR00045 Sigma-54 factor signature 408 426 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 PRINTS PR00045 Sigma-54 factor signature 147 164 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 PRINTS PR00045 Sigma-54 factor signature 333 345 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 PRINTS PR00045 Sigma-54 factor signature 349 360 2.0E-26 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 321 340 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 413 420 - T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 432 1.3E-138 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 PIRSF PIRSF000774 1 434 9.8E-134 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 Pfam PF04963 Sigma-54 factor, core binding domain 78 261 3.1E-54 T 29-03-2018 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 Pfam PF04552 Sigma-54, DNA binding domain 274 432 3.3E-62 T 29-03-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding CSW12_RS25375 7e2a003defba3935471e3b5785cc39c0 435 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 2.2E-13 T 29-03-2018 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CSW12_RS13040 c772346b65a492aa035c72d6fb3b7373 267 SUPERFAMILY SSF110710 5 266 7.32E-97 T 29-03-2018 CSW12_RS13040 c772346b65a492aa035c72d6fb3b7373 267 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 35 263 6.0E-81 T 29-03-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 CSW12_RS20625 3fcb30fada1a778fe4cc018e746fc177 226 SUPERFAMILY SSF158560 4 99 1.44E-28 T 29-03-2018 CSW12_RS20625 3fcb30fada1a778fe4cc018e746fc177 226 Pfam PF06570 Protein of unknown function (DUF1129) 36 225 8.6E-10 T 29-03-2018 IPR009214 Protein of unknown function DUF1129 CSW12_RS20625 3fcb30fada1a778fe4cc018e746fc177 226 Gene3D G3DSA:1.10.1900.10 12 84 2.8E-23 T 29-03-2018 CSW12_RS27725 bc86e035f7232d6316ea16d38b14414d 171 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 1.1E-47 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CSW12_RS27725 bc86e035f7232d6316ea16d38b14414d 171 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CSW12_RS27725 bc86e035f7232d6316ea16d38b14414d 171 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 2.2E-39 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CSW12_RS27725 bc86e035f7232d6316ea16d38b14414d 171 Gene3D G3DSA:3.30.70.560 1 159 2.0E-59 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CSW12_RS27725 bc86e035f7232d6316ea16d38b14414d 171 SUPERFAMILY SSF55083 4 149 4.05E-53 T 29-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CSW12_RS20960 d26c8bf59f51946ddb11a6c0c0b4f01a 288 Gene3D G3DSA:1.10.3720.10 12 282 5.3E-38 T 29-03-2018 CSW12_RS20960 d26c8bf59f51946ddb11a6c0c0b4f01a 288 SUPERFAMILY SSF161098 19 284 6.82E-37 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS20960 d26c8bf59f51946ddb11a6c0c0b4f01a 288 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 21 287 2.7E-79 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CSW12_RS20960 d26c8bf59f51946ddb11a6c0c0b4f01a 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 284 2.4E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS12670 3aaa15f520cd1b9c4c882ca6932f27ce 71 SUPERFAMILY SSF47413 1 68 9.57E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS12670 3aaa15f520cd1b9c4c882ca6932f27ce 71 Gene3D G3DSA:1.10.260.40 3 71 1.4E-10 T 29-03-2018 CSW12_RS12670 3aaa15f520cd1b9c4c882ca6932f27ce 71 SMART SM00530 6 62 2.2E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS12670 3aaa15f520cd1b9c4c882ca6932f27ce 71 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 1.6E-24 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 210 1.0E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 SMART SM00448 1 111 6.5E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 Gene3D G3DSA:1.10.10.10 116 215 2.0E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 SMART SM00862 139 210 1.6E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 Gene3D G3DSA:3.40.50.2300 1 115 2.3E-34 T 29-03-2018 CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 Pfam PF00072 Response regulator receiver domain 3 111 1.7E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS13370 9aa6e23c474cdd27b6b07fdb68a57911 215 SUPERFAMILY SSF52172 1 167 1.66E-37 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS04785 ee519fa841763d6cfd38923c6c23a046 275 Gene3D G3DSA:1.10.3720.10 9 273 7.2E-50 T 29-03-2018 CSW12_RS04785 ee519fa841763d6cfd38923c6c23a046 275 SUPERFAMILY SSF161098 13 263 1.68E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS04785 ee519fa841763d6cfd38923c6c23a046 275 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 6 269 5.0E-128 T 29-03-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CSW12_RS04785 ee519fa841763d6cfd38923c6c23a046 275 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 4 265 3.3E-99 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CSW12_RS04785 ee519fa841763d6cfd38923c6c23a046 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 267 2.5E-27 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 Gene3D G3DSA:3.30.1180.20 183 331 1.1E-53 T 29-03-2018 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 327 7.6E-136 T 29-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 SUPERFAMILY SSF101473 357 580 1.06E-44 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 Pfam PF02733 Dak1 domain 18 326 1.5E-125 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 Gene3D G3DSA:3.40.50.10440 11 182 1.0E-67 T 29-03-2018 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 Pfam PF02734 DAK2 domain 398 579 1.7E-51 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 SMART SM01120 397 580 2.3E-57 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS04160 b430e655435ac2ba1dc57fbf2b4838d2 583 SUPERFAMILY SSF82549 11 328 3.14E-121 T 29-03-2018 CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 Gene3D G3DSA:1.10.1660.10 1 58 2.2E-17 T 29-03-2018 CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 SUPERFAMILY SSF46955 2 106 2.16E-24 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 Pfam PF14526 Integron-associated effector binding protein 121 268 7.7E-16 T 29-03-2018 IPR029441 Integron-associated effector binding protein CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 SUPERFAMILY SSF55136 119 269 3.14E-19 T 29-03-2018 CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 Gene3D G3DSA:1.10.1660.10 59 125 6.8E-7 T 29-03-2018 CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 Gene3D G3DSA:3.20.80.10 126 269 5.4E-29 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 Pfam PF13411 MerR HTH family regulatory protein 2 70 8.7E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 SMART SM00422 2 72 7.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS14880 f0c2cf3abbe3de2c35dbe43b625f0fac 269 SMART SM00871 118 269 1.3E-24 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS25245 96540d506adec48a533718c4c8011193 143 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 8.3E-13 T 29-03-2018 CSW12_RS25245 96540d506adec48a533718c4c8011193 143 Pfam PF01037 Lrp/AsnC ligand binding domain 82 128 6.3E-9 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CSW12_RS25245 96540d506adec48a533718c4c8011193 143 Gene3D G3DSA:1.10.10.10 8 57 2.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25245 96540d506adec48a533718c4c8011193 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 7.4E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS25245 96540d506adec48a533718c4c8011193 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 7.4E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS25245 96540d506adec48a533718c4c8011193 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 7.4E-10 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS25245 96540d506adec48a533718c4c8011193 143 Gene3D G3DSA:3.30.70.920 58 143 1.1E-14 T 29-03-2018 CSW12_RS25245 96540d506adec48a533718c4c8011193 143 SMART SM00344 8 114 4.6E-28 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CSW12_RS25245 96540d506adec48a533718c4c8011193 143 SUPERFAMILY SSF54909 70 141 1.29E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS25245 96540d506adec48a533718c4c8011193 143 SUPERFAMILY SSF46785 6 67 2.28E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 2.1E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 318 352 4.3E-7 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 300 7.8E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.809 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 SUPERFAMILY SSF51161 254 446 1.39E-51 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Pfam PF00483 Nucleotidyl transferase 6 211 1.8E-25 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Gene3D G3DSA:3.90.550.10 2 245 6.9E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 452 4.3E-185 T 29-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Gene3D G3DSA:2.160.10.10 311 440 3.4E-35 T 29-03-2018 CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 SUPERFAMILY SSF53448 5 307 2.7E-66 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 Gene3D G3DSA:2.160.10.10 246 310 1.6E-16 T 29-03-2018 CSW12_RS27590 40b086c1ae9d18a375c5bb1840f7a472 459 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS25480 81109cc4a617f193e766470d3bb06510 268 Pfam PF04018 Domain of unknown function (DUF368) 12 239 1.6E-53 T 29-03-2018 IPR007163 Protein of unknown function DUF368 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 Gene3D G3DSA:3.10.50.40 127 248 1.3E-38 T 29-03-2018 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 SUPERFAMILY SSF54534 123 224 8.5E-32 T 29-03-2018 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 Pfam PF13616 PPIC-type PPIASE domain 133 226 1.5E-24 T 29-03-2018 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 163 184 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 281 21.899 T 29-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 Gene3D G3DSA:1.10.4030.10 24 126 1.5E-9 T 29-03-2018 CSW12_RS05340 41a5381a740efd82f64a0db78a37a88d 285 SUPERFAMILY SSF109998 28 164 4.71E-18 T 29-03-2018 IPR027304 Trigger factor/SurA domain CSW12_RS07335 aed0779579709fc75e75736b1a5bd8ec 152 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 9 147 3.2E-67 T 29-03-2018 IPR014203 Sporulation stage V, protein AC CSW12_RS07335 aed0779579709fc75e75736b1a5bd8ec 152 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 26 143 2.3E-41 T 29-03-2018 IPR005562 SpoVA CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:2.30.24.10 1 57 2.7E-25 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 Pfam PF03123 CAT RNA binding domain 6 60 8.4E-24 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 Pfam PF00874 PRD domain 80 166 2.2E-25 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 Pfam PF00874 PRD domain 185 275 2.1E-21 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 SMART SM01061 5 63 1.0E-27 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:1.10.1790.10 58 169 2.1E-26 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 Gene3D G3DSA:1.10.1790.10 170 279 3.6E-22 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 SUPERFAMILY SSF63520 181 277 1.18E-24 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 SUPERFAMILY SSF63520 60 171 8.63E-32 T 29-03-2018 IPR011608 PRD domain GO:0006355 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 SUPERFAMILY SSF50151 6 57 3.53E-17 T 29-03-2018 IPR004341 CAT RNA-binding domain GO:0003723 CSW12_RS07430 3b24c08d92c765a4a882eaba1eb0d6e1 282 ProSitePatterns PS00654 PRD domain signature. 102 114 - T 29-03-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 CSW12_RS14695 7faee5ec575d69db79acba1fa68028bd 413 Gene3D G3DSA:3.40.50.1820 23 413 5.0E-105 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS14695 7faee5ec575d69db79acba1fa68028bd 413 SUPERFAMILY SSF53474 31 386 2.2E-46 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 SMART SM00418 11 90 7.4E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 SUPERFAMILY SSF46785 1 85 2.95E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 Gene3D G3DSA:1.10.10.10 5 91 5.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 3.4E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 7.9E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 7.9E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29080 ec6ec344d7017d05950bfafa9a08a1cb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 7.9E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 SMART SM00418 11 90 7.4E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 SUPERFAMILY SSF46785 1 85 2.95E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 Gene3D G3DSA:1.10.10.10 5 91 5.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 3.4E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 7.9E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 7.9E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS29610 ec6ec344d7017d05950bfafa9a08a1cb 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 7.9E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 337 40.954 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 337 4.6E-120 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 SUPERFAMILY SSF102114 7 306 5.23E-79 T 29-03-2018 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 316 2.4E-36 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 Pfam PF04055 Radical SAM superfamily 19 183 1.1E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 Gene3D G3DSA:3.20.20.70 1 337 3.0E-84 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 SMART SM00729 14 225 6.9E-16 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS17265 c5ad7cd82485e6c02057c23bdd9867aa 337 Pfam PF13353 4Fe-4S single cluster domain 21 128 1.6E-7 T 29-03-2018 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 Gene3D G3DSA:3.30.70.360 277 374 1.4E-27 T 29-03-2018 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 SUPERFAMILY SSF53187 5 187 1.63E-63 T 29-03-2018 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 SUPERFAMILY SSF53187 385 467 1.63E-63 T 29-03-2018 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 463 6.6E-174 T 29-03-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 Pfam PF01546 Peptidase family M20/M25/M40 87 464 2.3E-34 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 117 156 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 Gene3D G3DSA:3.40.630.10 6 194 5.5E-24 T 29-03-2018 CSW12_RS23205 5addbd1d35dd5821d41a57bc24b8d90b 468 SUPERFAMILY SSF55031 187 376 3.49E-54 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS01975 0bf3cd30f995fa43c523a6e345835295 140 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-18 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS01975 0bf3cd30f995fa43c523a6e345835295 140 PRINTS PR01438 Universal stress protein signature 100 112 1.6E-18 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS01975 0bf3cd30f995fa43c523a6e345835295 140 PRINTS PR01438 Universal stress protein signature 118 140 1.6E-18 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS01975 0bf3cd30f995fa43c523a6e345835295 140 Gene3D G3DSA:3.40.50.620 2 140 2.8E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS01975 0bf3cd30f995fa43c523a6e345835295 140 Pfam PF00582 Universal stress protein family 1 140 1.1E-27 T 29-03-2018 IPR006016 UspA GO:0006950 CSW12_RS01975 0bf3cd30f995fa43c523a6e345835295 140 SUPERFAMILY SSF52402 1 140 2.34E-29 T 29-03-2018 CSW12_RS09715 13b193563c0812e62d835bd1b6dcaced 139 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 9.6E-30 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CSW12_RS09715 13b193563c0812e62d835bd1b6dcaced 139 Pfam PF03061 Thioesterase superfamily 18 102 7.6E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS09715 13b193563c0812e62d835bd1b6dcaced 139 Gene3D G3DSA:3.10.129.10 2 139 7.2E-33 T 29-03-2018 CSW12_RS09715 13b193563c0812e62d835bd1b6dcaced 139 PIRSF PIRSF003230 1 135 6.8E-30 T 29-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CSW12_RS09715 13b193563c0812e62d835bd1b6dcaced 139 SUPERFAMILY SSF54637 2 133 3.09E-36 T 29-03-2018 IPR029069 HotDog domain CSW12_RS20505 76a3ad343f9c051302708639db145614 450 SMART SM00878 337 443 2.6E-72 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.6E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.0E-47 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 7.5E-45 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 Gene3D G3DSA:3.30.470.20 210 446 2.5E-102 T 29-03-2018 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 1.9E-240 T 29-03-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 Gene3D G3DSA:3.40.50.20 1 123 3.9E-54 T 29-03-2018 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 SUPERFAMILY SSF52440 1 113 2.59E-51 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS20505 76a3ad343f9c051302708639db145614 450 Gene3D G3DSA:3.30.1490.20 124 209 6.0E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 SUPERFAMILY SSF56059 83 349 4.24E-67 T 29-03-2018 CSW12_RS20505 76a3ad343f9c051302708639db145614 450 SUPERFAMILY SSF51246 332 445 1.73E-48 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CSW12_RS11655 d007e91f32c5f09dcd10ae9195764f50 223 SUPERFAMILY SSF52540 4 222 2.66E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11655 d007e91f32c5f09dcd10ae9195764f50 223 Pfam PF00005 ABC transporter 24 173 9.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS11655 d007e91f32c5f09dcd10ae9195764f50 223 SMART SM00382 33 220 1.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS11655 d007e91f32c5f09dcd10ae9195764f50 223 Gene3D G3DSA:3.40.50.300 1 223 1.5E-66 T 29-03-2018 CSW12_RS11655 d007e91f32c5f09dcd10ae9195764f50 223 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS30690 2d0668073e928df2869bf2dd2152a39a 155 Gene3D G3DSA:2.60.40.810 27 150 5.7E-7 T 29-03-2018 CSW12_RS10280 759703dd798e08a5a1b164da04239786 375 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 374 3.2E-62 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS10280 759703dd798e08a5a1b164da04239786 375 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 197 371 7.3E-25 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 SMART SM00421 137 194 2.5E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 SUPERFAMILY SSF46894 129 199 6.8E-19 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 Gene3D G3DSA:3.40.50.2300 1 139 2.0E-33 T 29-03-2018 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 4.3E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 Pfam PF00072 Response regulator receiver domain 4 116 5.1E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 3.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 3.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 3.0E-11 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 Gene3D G3DSA:1.10.10.10 140 200 2.2E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 SUPERFAMILY SSF52172 1 128 2.85E-30 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS26555 faafdb7da1bddef4c1774058c803325e 200 SMART SM00448 2 115 3.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 SUPERFAMILY SSF52540 2 218 1.41E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 PIRSF PIRSF003128 1 571 1.8E-184 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 Gene3D G3DSA:3.40.50.300 1 238 2.7E-25 T 29-03-2018 CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 Gene3D G3DSA:3.40.50.300 239 547 4.8E-19 T 29-03-2018 CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 521 6.0E-15 T 29-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 5.1E-189 T 29-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 SUPERFAMILY SSF52540 4 50 2.67E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20455 2070724f9dc69570eb859a2bcaac8d15 579 SUPERFAMILY SSF52540 303 521 2.67E-28 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 Gene3D G3DSA:3.30.1380.10 1 120 2.3E-19 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 Pfam PF08239 Bacterial SH3 domain 155 198 7.8E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 Gene3D G3DSA:2.40.50.110 130 200 3.9E-10 T 29-03-2018 CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 SUPERFAMILY SSF55166 10 120 5.1E-23 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 SMART SM00287 147 201 0.32 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 SMART SM00287 220 280 0.15 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 56 120 5.3E-17 T 29-03-2018 CSW12_RS14340 45bb8735b6e71982143762ce8d208781 282 Gene3D G3DSA:2.30.30.410 207 280 1.6E-10 T 29-03-2018 CSW12_RS09420 8c0a80996e723d67eba0cfe65d661fe6 306 Pfam PF00005 ABC transporter 27 167 1.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09420 8c0a80996e723d67eba0cfe65d661fe6 306 SUPERFAMILY SSF52540 8 224 1.81E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09420 8c0a80996e723d67eba0cfe65d661fe6 306 Gene3D G3DSA:3.30.70.1370 227 299 0.0012 T 29-03-2018 CSW12_RS09420 8c0a80996e723d67eba0cfe65d661fe6 306 SMART SM00382 35 216 1.3E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS09420 8c0a80996e723d67eba0cfe65d661fe6 306 Gene3D G3DSA:3.40.50.300 4 226 3.7E-59 T 29-03-2018 CSW12_RS09420 8c0a80996e723d67eba0cfe65d661fe6 306 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26940 12f8aff3f8345ba7402cdb0095db1844 127 Pfam PF04138 GtrA-like protein 6 119 8.7E-30 T 29-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 152 8.6E-44 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 234 246 - T 29-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 SMART SM01350 166 297 2.9E-6 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 22 9.9E-27 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 155 183 9.9E-27 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 58 87 9.9E-27 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 230 257 9.9E-27 T 29-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 Gene3D G3DSA:3.40.50.720 1 167 6.6E-32 T 29-03-2018 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 Gene3D G3DSA:1.10.1040.10 168 296 7.0E-38 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 SUPERFAMILY SSF51735 1 152 5.87E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 SUPERFAMILY SSF48179 164 296 2.79E-40 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 297 9.7E-149 T 29-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CSW12_RS11020 dc0bb04f63dc65b0db0a27a8b05594c7 297 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 166 275 2.5E-24 T 29-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CSW12_RS05645 2bea06c67c0198ef36ab19eaaaab9333 119 Pfam PF07098 Protein of unknown function (DUF1360) 11 112 1.4E-37 T 29-03-2018 IPR010773 Mycobacterium phage PG1, Gp7 CSW12_RS08415 c8b70843440f16db7bce025926670444 205 Gene3D G3DSA:3.40.50.300 85 188 7.8E-30 T 29-03-2018 CSW12_RS08415 c8b70843440f16db7bce025926670444 205 Hamap MF_00328 Guanylate kinase [gmk]. 4 188 37.038 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CSW12_RS08415 c8b70843440f16db7bce025926670444 205 Pfam PF00625 Guanylate kinase 8 184 6.2E-53 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CSW12_RS08415 c8b70843440f16db7bce025926670444 205 SUPERFAMILY SSF52540 3 192 2.67E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08415 c8b70843440f16db7bce025926670444 205 Gene3D G3DSA:3.40.50.300 1 52 2.1E-9 T 29-03-2018 CSW12_RS08415 c8b70843440f16db7bce025926670444 205 ProSitePatterns PS00856 Guanylate kinase-like signature. 41 58 - T 29-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CSW12_RS08415 c8b70843440f16db7bce025926670444 205 SMART SM00072 5 188 7.2E-78 T 29-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CSW12_RS08415 c8b70843440f16db7bce025926670444 205 Gene3D G3DSA:3.30.63.10 53 84 2.1E-25 T 29-03-2018 CSW12_RS08415 c8b70843440f16db7bce025926670444 205 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 1.2E-73 T 29-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CSW12_RS29915 870c69d5149475baf6a4d3cc8b49b664 584 Pfam PF01740 STAS domain 437 533 1.6E-18 T 29-03-2018 IPR002645 STAS domain CSW12_RS29915 870c69d5149475baf6a4d3cc8b49b664 584 Gene3D G3DSA:3.30.750.24 421 549 3.0E-22 T 29-03-2018 IPR002645 STAS domain CSW12_RS29915 870c69d5149475baf6a4d3cc8b49b664 584 SUPERFAMILY SSF52091 436 538 4.91E-16 T 29-03-2018 IPR002645 STAS domain CSW12_RS29915 870c69d5149475baf6a4d3cc8b49b664 584 TIGRFAM TIGR00815 sulP: sulfate permease 9 533 2.5E-117 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 CSW12_RS29915 870c69d5149475baf6a4d3cc8b49b664 584 Pfam PF00916 Sulfate permease family 15 379 4.1E-94 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 Pfam PF00753 Metallo-beta-lactamase superfamily 508 718 1.9E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 228 398 4.3E-35 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 SMART SM00849 509 719 2.6E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 SUPERFAMILY SSF56281 502 761 4.74E-54 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 Pfam PF03772 Competence protein 207 469 8.1E-64 T 29-03-2018 IPR004477 ComEC/Rec2-related protein CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 78 748 7.5E-130 T 29-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 Gene3D G3DSA:3.60.15.10 499 742 9.5E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS21245 bd483c2bb5765b194a0f777048b9e13d 773 Pfam PF13567 Domain of unknown function (DUF4131) 21 167 2.1E-21 T 29-03-2018 IPR025405 Domain of unknown function DUF4131 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.2E-50 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 Pfam PF00574 Clp protease 14 192 2.1E-83 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 42.771 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 SUPERFAMILY SSF52096 11 191 5.68E-69 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 7.2E-99 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS13725 878cec0ca937dba459a802487faf5da7 193 Gene3D G3DSA:3.90.226.10 2 193 3.3E-43 T 29-03-2018 CSW12_RS15990 af279d8a257fc52e33e1e9b71976c2d9 174 Pfam PF00583 Acetyltransferase (GNAT) family 42 145 1.3E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS15990 af279d8a257fc52e33e1e9b71976c2d9 174 Gene3D G3DSA:3.40.630.30 3 174 2.0E-15 T 29-03-2018 CSW12_RS15990 af279d8a257fc52e33e1e9b71976c2d9 174 SUPERFAMILY SSF55729 15 170 5.15E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS05170 bafe0601a881dacb884bc1dc99d7983b 436 Pfam PF05065 Phage capsid family 152 419 3.1E-58 T 29-03-2018 IPR024455 Phage capsid CSW12_RS05170 bafe0601a881dacb884bc1dc99d7983b 436 SUPERFAMILY SSF56563 148 418 5.23E-37 T 29-03-2018 CSW12_RS05170 bafe0601a881dacb884bc1dc99d7983b 436 Gene3D G3DSA:3.30.2400.10 173 322 1.5E-15 T 29-03-2018 CSW12_RS05170 bafe0601a881dacb884bc1dc99d7983b 436 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 43 418 2.1E-51 T 29-03-2018 IPR024455 Phage capsid CSW12_RS08170 9adf1d6aac21f7247409c8f6d8a68af2 120 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 38 118 2.8E-24 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CSW12_RS08170 9adf1d6aac21f7247409c8f6d8a68af2 120 Hamap MF_00910 Cell division protein FtsL [ftsL]. 38 120 13.276 T 29-03-2018 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CSW12_RS08170 9adf1d6aac21f7247409c8f6d8a68af2 120 Pfam PF04977 Septum formation initiator 45 111 7.8E-14 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CSW12_RS07035 718584c36c1d9ea101d490855a07a5fa 292 SMART SM00422 9 78 9.7E-11 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS07035 718584c36c1d9ea101d490855a07a5fa 292 SUPERFAMILY SSF46955 9 82 1.01E-15 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS07035 718584c36c1d9ea101d490855a07a5fa 292 Pfam PF13411 MerR HTH family regulatory protein 9 77 1.9E-15 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS07035 718584c36c1d9ea101d490855a07a5fa 292 Gene3D G3DSA:1.10.1660.10 7 257 1.7E-19 T 29-03-2018 CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 SUPERFAMILY SSF46894 128 222 1.5E-20 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 SMART SM00862 146 221 1.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 SUPERFAMILY SSF52172 3 162 2.13E-43 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 Gene3D G3DSA:3.40.50.2300 3 125 1.2E-36 T 29-03-2018 CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 SMART SM00448 3 113 5.8E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 Gene3D G3DSA:1.10.10.10 126 225 6.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 4.7E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS18065 522f623d37a1de435758a5cf3f849be6 225 Pfam PF00072 Response regulator receiver domain 5 113 6.5E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS20080 158c41884f069388d1aed4643d697bb2 307 Gene3D G3DSA:3.40.50.1820 28 307 1.9E-38 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS20080 158c41884f069388d1aed4643d697bb2 307 SUPERFAMILY SSF53474 20 305 1.39E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS20080 158c41884f069388d1aed4643d697bb2 307 Pfam PF12146 Serine aminopeptidase, S33 80 189 7.0E-10 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS08675 79fd93391113b21f9d9e8b355b855d82 420 SMART SM00228 185 259 1.1E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS08675 79fd93391113b21f9d9e8b355b855d82 420 SUPERFAMILY SSF50156 174 268 3.42E-20 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS08675 79fd93391113b21f9d9e8b355b855d82 420 Gene3D G3DSA:2.30.42.10 200 288 5.0E-21 T 29-03-2018 CSW12_RS08675 79fd93391113b21f9d9e8b355b855d82 420 Pfam PF02163 Peptidase family M50 8 406 6.5E-82 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CSW12_RS08675 79fd93391113b21f9d9e8b355b855d82 420 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 419 4.4E-113 T 29-03-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CSW12_RS08675 79fd93391113b21f9d9e8b355b855d82 420 Pfam PF13180 PDZ domain 203 267 1.2E-8 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.8E-9 T 29-03-2018 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.8E-9 T 29-03-2018 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.8E-9 T 29-03-2018 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 7.8E-9 T 29-03-2018 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 Gene3D G3DSA:3.50.50.60 1 123 3.4E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 Gene3D G3DSA:3.50.50.60 124 157 8.1E-4 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 289 3.4E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 SUPERFAMILY SSF51905 1 308 5.46E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 Gene3D G3DSA:3.50.50.60 158 311 1.2E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 274 3.8E-7 T 29-03-2018 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 3.8E-7 T 29-03-2018 CSW12_RS24495 8e192b5373139817f8903437b1756a49 356 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.8E-7 T 29-03-2018 CSW12_RS25760 35ba8f73861d07a163c3e5aecc65ed42 234 Gene3D G3DSA:3.20.20.370 1 233 6.3E-78 T 29-03-2018 CSW12_RS25760 35ba8f73861d07a163c3e5aecc65ed42 234 SUPERFAMILY SSF88713 1 229 2.89E-73 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS25760 35ba8f73861d07a163c3e5aecc65ed42 234 Pfam PF04794 YdjC-like protein 3 228 1.6E-61 T 29-03-2018 IPR006879 Carbohydrate deacetylase YdjC-like CSW12_RS25760 35ba8f73861d07a163c3e5aecc65ed42 234 Hamap MF_01246 Chitooligosaccharide deacetylase [chbG]. 2 234 40.925 T 29-03-2018 IPR022948 Chitooligosaccharide deacetylase ChbG-like, bacteria GO:0000272|GO:0016811 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PIRSF PIRSF037149 1 800 0.0 T 29-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 789 6.5E-301 T 29-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 554 616 4.1E-10 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 4.6E-19 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.6E-19 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 4.6E-19 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 4.6E-19 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 4.6E-19 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 1.6E-12 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 1.6E-12 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 1.6E-12 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.6E-12 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 625 758 1.3E-25 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Pfam PF04324 BFD-like [2Fe-2S] binding domain 414 463 4.0E-15 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Pfam PF04324 BFD-like [2Fe-2S] binding domain 480 529 1.4E-10 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Gene3D G3DSA:3.50.50.60 1 100 3.9E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Gene3D G3DSA:3.50.50.60 101 240 6.2E-30 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 SUPERFAMILY SSF56014 625 761 1.3E-45 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00397 Sirohaem Fe-binding site signature 628 646 6.5E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 6.5E-6 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Gene3D G3DSA:3.50.50.60 243 310 8.4E-7 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 SUPERFAMILY SSF55124 492 615 2.13E-23 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Gene3D G3DSA:3.90.480.10 450 619 4.6E-12 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 281 4.1E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 Gene3D G3DSA:3.30.413.10 623 798 1.6E-34 T 29-03-2018 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 671 687 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 SUPERFAMILY SSF51905 2 191 5.08E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17200 274bf30936a7ad259845d36cf8deb001 801 SUPERFAMILY SSF51905 141 305 2.71E-28 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Pfam PF00672 HAMP domain 303 352 4.4E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Gene3D G3DSA:3.30.450.20 36 168 5.3E-21 T 29-03-2018 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 432 611 1.8E-44 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Gene3D G3DSA:1.10.287.950 419 660 5.2E-56 T 29-03-2018 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Pfam PF02743 Cache domain 47 266 3.5E-30 T 29-03-2018 IPR033479 Double Cache domain 1 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Gene3D G3DSA:1.10.287.950 331 418 1.8E-9 T 29-03-2018 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 SMART SM00283 384 659 1.2E-75 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 SUPERFAMILY SSF103190 98 190 6.36E-13 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 SUPERFAMILY SSF58104 390 659 4.05E-72 T 29-03-2018 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 SUPERFAMILY SSF58104 323 357 4.05E-72 T 29-03-2018 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 1.2E-5 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 511 540 1.2E-5 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 SMART SM00304 303 355 5.8E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01590 452c0acc3114537226acf3eef6773496 660 Gene3D G3DSA:3.30.450.20 169 272 4.1E-17 T 29-03-2018 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 338 1.1E-116 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 Pfam PF04055 Radical SAM superfamily 18 183 7.2E-28 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 338 40.228 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 SMART SM00729 14 222 3.7E-9 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 Pfam PF13353 4Fe-4S single cluster domain 21 128 4.9E-9 T 29-03-2018 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 Gene3D G3DSA:3.20.20.70 1 338 2.8E-79 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 316 1.5E-36 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CSW12_RS09910 3a3c211520b15b3f86c7f14d1a8bdd82 338 SUPERFAMILY SSF102114 7 282 3.01E-77 T 29-03-2018 CSW12_RS26215 6e8f097a2454c139ae832dcd4ec12db3 236 Gene3D G3DSA:3.30.360.40 168 236 2.5E-25 T 29-03-2018 CSW12_RS26215 6e8f097a2454c139ae832dcd4ec12db3 236 SUPERFAMILY SSF143842 32 233 1.57E-51 T 29-03-2018 IPR014794 TATA-box binding CSW12_RS26215 6e8f097a2454c139ae832dcd4ec12db3 236 Pfam PF08680 TATA-box binding 48 236 1.2E-46 T 29-03-2018 IPR014794 TATA-box binding CSW12_RS26215 6e8f097a2454c139ae832dcd4ec12db3 236 Gene3D G3DSA:3.30.2030.10 33 161 5.2E-31 T 29-03-2018 CSW12_RS25320 1aa734858d043d1a8df1090b372d8c3f 77 Pfam PF03840 Preprotein translocase SecG subunit 4 75 3.6E-23 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CSW12_RS25320 1aa734858d043d1a8df1090b372d8c3f 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 1.1E-24 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CSW12_RS25320 1aa734858d043d1a8df1090b372d8c3f 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 1.0E-10 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CSW12_RS25320 1aa734858d043d1a8df1090b372d8c3f 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.0E-10 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CSW12_RS25320 1aa734858d043d1a8df1090b372d8c3f 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.0E-10 T 29-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 Gene3D G3DSA:3.90.1150.10 317 432 6.3E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 Pfam PF00202 Aminotransferase class-III 38 404 7.7E-72 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 430 95.505 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 428 4.9E-169 T 29-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 SUPERFAMILY SSF53383 4 428 2.04E-124 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 Gene3D G3DSA:3.90.1150.10 2 171 1.4E-44 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS01255 0b7329ade5a8795394dd8a55669df71e 434 Gene3D G3DSA:3.40.640.10 172 316 2.0E-39 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.3E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 SUPERFAMILY SSF47729 1 90 8.24E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 SMART SM00411 1 90 3.8E-46 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS31075 095fc827f26339a902822b2dd184d0d9 90 Gene3D G3DSA:4.10.520.10 1 90 1.2E-35 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS13775 5da3a34fda913e80ed9843b740735f39 127 Pfam PF13789 Domain of unknown function (DUF4181) 18 119 1.3E-30 T 29-03-2018 IPR025441 Protein of unknown function DUF4181 CSW12_RS10005 fcc5105c9564183a61759d9c8ed54253 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 301 7.2E-65 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS10005 fcc5105c9564183a61759d9c8ed54253 310 Gene3D G3DSA:3.90.245.10 1 310 6.1E-75 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS10005 fcc5105c9564183a61759d9c8ed54253 310 SUPERFAMILY SSF53590 1 309 4.97E-81 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 Gene3D G3DSA:3.40.640.10 5 289 1.2E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 SUPERFAMILY SSF53383 259 422 6.54E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 SUPERFAMILY SSF53383 24 227 6.54E-110 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 PIRSF PIRSF001434 3 424 2.1E-122 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 Gene3D G3DSA:3.90.1150.10 291 432 3.6E-49 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 422 3.0E-181 T 29-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CSW12_RS26815 137badac3c76f447ebc274dace5e3a38 432 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 422 5.0E-126 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 Pfam PF00027 Cyclic nucleotide-binding domain 34 120 3.2E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 SMART SM00100 15 133 8.6E-5 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 Gene3D G3DSA:2.60.120.10 7 148 2.1E-25 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 SUPERFAMILY SSF51206 23 147 4.32E-32 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 Pfam PF13545 Crp-like helix-turn-helix domain 154 226 1.2E-10 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 SUPERFAMILY SSF46785 150 227 2.87E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 SMART SM00419 172 220 5.8E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS00720 b90ad2a17be82793c8bc2ae9121b22a4 229 Gene3D G3DSA:1.10.10.10 149 227 1.4E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09175 fc753119dc78705bad3dc3ed3fe6ab74 464 PIRSF PIRSF006060 2 463 9.3E-80 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS09175 fc753119dc78705bad3dc3ed3fe6ab74 464 ProSitePatterns PS00218 Amino acid permeases signature. 38 68 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS09175 fc753119dc78705bad3dc3ed3fe6ab74 464 Pfam PF00324 Amino acid permease 13 450 8.5E-119 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS09175 fc753119dc78705bad3dc3ed3fe6ab74 464 TIGRFAM TIGR01773 GABAperm: GABA permease 4 447 5.5E-207 T 29-03-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 CSW12_RS13535 8f52b8ad4ace30053c2ecbefdf22c553 127 SUPERFAMILY SSF69118 15 122 1.44E-27 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS13535 8f52b8ad4ace30053c2ecbefdf22c553 127 Pfam PF02627 Carboxymuconolactone decarboxylase family 34 116 4.0E-20 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CSW12_RS13535 8f52b8ad4ace30053c2ecbefdf22c553 127 Gene3D G3DSA:1.20.1290.10 1 127 3.3E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 Pfam PF13481 AAA domain 60 222 1.5E-17 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 45.323 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 SUPERFAMILY SSF54211 303 456 1.33E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 SUPERFAMILY SSF54211 255 269 1.33E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 Gene3D G3DSA:3.30.230.10 281 457 4.2E-32 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 322 345 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 82 110 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 213 241 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 248 274 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 10 34 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 124 141 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 PRINTS PR01874 DNA repair protein radA signature 174 198 6.2E-94 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 Gene3D G3DSA:3.40.50.300 71 279 1.9E-45 T 29-03-2018 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 SUPERFAMILY SSF52540 68 293 3.27E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 SMART SM00382 90 244 1.5E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 1.8E-211 T 29-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CSW12_RS27840 585b61d92ad2bfed0a39aff93ac76882 458 Pfam PF13541 Subunit ChlI of Mg-chelatase 363 430 9.1E-9 T 29-03-2018 CSW12_RS15420 ebd568acb0b8b3378b2c65b98c5b2a72 439 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 36 206 6.1E-51 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS15420 ebd568acb0b8b3378b2c65b98c5b2a72 439 Gene3D G3DSA:1.20.1170.10 30 438 7.8E-17 T 29-03-2018 CSW12_RS15420 ebd568acb0b8b3378b2c65b98c5b2a72 439 SUPERFAMILY SSF58100 20 265 5.23E-44 T 29-03-2018 CSW12_RS28655 6eb9cdae3bef3fd23433bd87feb029c2 423 Gene3D G3DSA:1.20.1250.20 208 421 1.7E-20 T 29-03-2018 CSW12_RS28655 6eb9cdae3bef3fd23433bd87feb029c2 423 Gene3D G3DSA:1.20.1250.20 1 205 1.4E-37 T 29-03-2018 CSW12_RS28655 6eb9cdae3bef3fd23433bd87feb029c2 423 Pfam PF07690 Major Facilitator Superfamily 19 363 2.3E-46 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS28655 6eb9cdae3bef3fd23433bd87feb029c2 423 SUPERFAMILY SSF103473 9 415 3.27E-62 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS28655 6eb9cdae3bef3fd23433bd87feb029c2 423 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 84 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 Gene3D G3DSA:3.20.20.140 85 252 0.1 T 29-03-2018 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 Pfam PF13382 Adenine deaminase C-terminal domain 410 571 1.5E-37 T 29-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 SUPERFAMILY SSF51338 6 82 2.16E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 SUPERFAMILY SSF51338 331 367 2.16E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 SUPERFAMILY SSF51556 82 327 5.45E-11 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 Gene3D G3DSA:2.30.40.10 272 371 4.7E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 Gene3D G3DSA:2.30.40.10 23 84 1.6E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12575 2a112124109e9a8b1491ad9da0d4f5c7 584 Pfam PF01979 Amidohydrolase family 78 362 1.5E-20 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 SUPERFAMILY SSF56712 1 600 9.16E-178 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Pfam PF01131 DNA topoisomerase 158 586 3.4E-127 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Pfam PF01751 Toprim domain 3 138 1.3E-9 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 SMART SM00436 130 225 4.5E-35 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Gene3D G3DSA:3.40.50.140 1 158 1.7E-35 T 29-03-2018 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 SMART SM00437 273 551 1.3E-86 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 SMART SM00493 1 130 4.2E-14 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Gene3D G3DSA:2.70.20.10 360 473 4.6E-26 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Gene3D G3DSA:1.10.460.10 474 609 9.7E-23 T 29-03-2018 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Gene3D G3DSA:1.10.460.10 164 350 2.2E-41 T 29-03-2018 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 1.9E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 1.9E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 514 528 1.9E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 1.9E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 1.9E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Pfam PF13342 C-terminal repeat of topoisomerase 656 713 4.9E-17 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 710 2.1E-191 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CSW12_RS18315 ef72af690e84ba092a696dd0d01093d0 714 Gene3D G3DSA:3.30.65.10 615 675 5.7E-4 T 29-03-2018 CSW12_RS24050 94d51723acdf588ae2add19e36eea4d6 260 Pfam PF01987 Mitochondrial biogenesis AIM24 8 225 9.6E-70 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CSW12_RS24050 94d51723acdf588ae2add19e36eea4d6 260 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 7 232 2.5E-34 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CSW12_RS24050 94d51723acdf588ae2add19e36eea4d6 260 SUPERFAMILY SSF51219 6 241 7.06E-84 T 29-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CSW12_RS24050 94d51723acdf588ae2add19e36eea4d6 260 Gene3D G3DSA:3.60.160.10 1 248 4.8E-78 T 29-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CSW12_RS11860 0829938ffd1a46e89b069d5a9c7d4ed5 498 Pfam PF12229 Putative peptidoglycan binding domain 266 344 7.7E-11 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CSW12_RS11860 0829938ffd1a46e89b069d5a9c7d4ed5 498 Pfam PF03734 L,D-transpeptidase catalytic domain 373 497 7.7E-15 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CSW12_RS11860 0829938ffd1a46e89b069d5a9c7d4ed5 498 SUPERFAMILY SSF141523 370 498 1.57E-28 T 29-03-2018 CSW12_RS11860 0829938ffd1a46e89b069d5a9c7d4ed5 498 SUPERFAMILY SSF143985 238 357 6.41E-30 T 29-03-2018 CSW12_RS11860 0829938ffd1a46e89b069d5a9c7d4ed5 498 Gene3D G3DSA:2.40.440.10 372 498 1.5E-22 T 29-03-2018 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 14 24 1.4E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 41 52 1.4E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 28 36 1.4E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 PRINTS PR00070 Dihydrofolate reductase signature 92 106 1.4E-12 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 29-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 PIRSF PIRSF000194 1 162 1.8E-61 T 29-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 SUPERFAMILY SSF53597 1 161 8.77E-60 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 Pfam PF00186 Dihydrofolate reductase 3 160 1.1E-61 T 29-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CSW12_RS16855 e4c8db113edf67ac0b72ba9ec661bbc8 162 Gene3D G3DSA:3.40.430.10 1 162 2.6E-55 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Pfam PF03454 MoeA C-terminal region (domain IV) 341 411 9.7E-19 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 SMART SM00852 189 327 2.6E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 SUPERFAMILY SSF53218 186 331 6.28E-38 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Pfam PF00994 Probable molybdopterin binding domain 189 325 1.8E-23 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Gene3D G3DSA:2.40.340.10 338 413 6.5E-18 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 323 1.5E-30 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Gene3D G3DSA:2.170.190.11 63 142 8.4E-23 T 29-03-2018 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 176 1.5E-38 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Gene3D G3DSA:3.90.105.10 143 171 2.6E-8 T 29-03-2018 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Gene3D G3DSA:3.90.105.10 26 62 5.0E-7 T 29-03-2018 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 SUPERFAMILY SSF63882 8 184 1.57E-50 T 29-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 Gene3D G3DSA:3.40.980.10 172 334 2.8E-47 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS17255 20d0294a1169ef6ccd6deb6a74e0f390 429 SUPERFAMILY SSF63867 338 412 5.49E-17 T 29-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS19160 0437ef2d98efcd9d3b81140e247e727b 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 4.3E-26 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS19160 0437ef2d98efcd9d3b81140e247e727b 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 17.93 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS19160 0437ef2d98efcd9d3b81140e247e727b 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 1.0E-26 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS19160 0437ef2d98efcd9d3b81140e247e727b 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 7.2E-20 T 29-03-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 CSW12_RS05615 c6c3ac7020143ba8d62f57e95b486a70 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 175 8.5E-69 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CSW12_RS05615 c6c3ac7020143ba8d62f57e95b486a70 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 177 1.3E-66 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CSW12_RS05615 c6c3ac7020143ba8d62f57e95b486a70 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 176 1.0E-100 T 29-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CSW12_RS05615 c6c3ac7020143ba8d62f57e95b486a70 181 Gene3D G3DSA:2.60.120.10 1 181 4.4E-68 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS05615 c6c3ac7020143ba8d62f57e95b486a70 181 SUPERFAMILY SSF51182 1 179 7.51E-71 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS13145 e13e8a556caa01b21a85aa7460e4f9fb 162 SUPERFAMILY SSF109854 9 130 3.48E-14 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS13145 e13e8a556caa01b21a85aa7460e4f9fb 162 Gene3D G3DSA:1.20.120.450 8 131 4.7E-6 T 29-03-2018 CSW12_RS04990 3da22a1a2b55ffa9413c73ee04160441 64 PIRSF PIRSF037666 1 59 5.4E-35 T 29-03-2018 IPR017257 Spore germination protein GerPD, predicted CSW12_RS20925 d21d69056bf710975c9181e3912f9401 327 SUPERFAMILY SSF53067 5 320 1.4E-70 T 29-03-2018 CSW12_RS20925 d21d69056bf710975c9181e3912f9401 327 Gene3D G3DSA:3.30.420.40 1 124 5.0E-34 T 29-03-2018 CSW12_RS20925 d21d69056bf710975c9181e3912f9401 327 Gene3D G3DSA:3.30.420.40 125 326 2.1E-63 T 29-03-2018 CSW12_RS20925 d21d69056bf710975c9181e3912f9401 327 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 323 3.7E-123 T 29-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CSW12_RS20925 d21d69056bf710975c9181e3912f9401 327 ProSitePatterns PS01125 ROK family signature. 139 166 - T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CSW12_RS20925 d21d69056bf710975c9181e3912f9401 327 Pfam PF00480 ROK family 7 319 1.1E-78 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SMART SM00851 949 1036 1.1E-25 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SUPERFAMILY SSF52335 936 1068 5.76E-32 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SMART SM01096 420 540 2.1E-65 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SUPERFAMILY SSF48108 395 546 1.29E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:3.40.50.20 4 117 3.4E-38 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:3.40.50.20 532 647 6.4E-60 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:3.30.1490.20 648 737 7.0E-23 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1064 13.489 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.131 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:3.30.470.20 120 401 1.1E-66 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-62 T 29-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 2.5E-41 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:3.30.470.20 738 927 2.7E-38 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SUPERFAMILY SSF56059 128 399 1.18E-108 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SMART SM01209 674 837 0.0024 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 29-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Pfam PF02142 MGS-like domain 950 1036 8.4E-19 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SUPERFAMILY SSF56059 666 927 3.54E-102 T 29-03-2018 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SUPERFAMILY SSF52440 1 127 4.17E-49 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 SUPERFAMILY SSF52440 549 668 1.11E-48 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:3.40.50.1380 928 1070 2.3E-34 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 7.3E-81 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 4.8E-40 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08325 7e3abcd768840e6ffa8a879ef8291a41 1072 Gene3D G3DSA:1.10.1030.10 402 531 3.8E-49 T 29-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 2.9E-117 T 29-03-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 Gene3D G3DSA:1.10.10.10 138 216 2.3E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 SUPERFAMILY SSF88659 123 210 1.57E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 Pfam PF04542 Sigma-70 region 2 36 105 5.5E-12 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 Pfam PF08281 Sigma-70, region 4 162 205 1.1E-9 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 Gene3D G3DSA:1.10.1740.10 12 116 1.1E-18 T 29-03-2018 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 SUPERFAMILY SSF88946 17 105 9.03E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 209 4.3E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 PIRSF PIRSF002939 5 216 3.4E-111 T 29-03-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 CSW12_RS27895 a6727c7cfbd4d74359595b6d82480aed 219 SMART SM00421 160 209 0.0091 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS23415 9da65e7721300759adb4d99e60cf1f38 619 Pfam PF02687 FtsX-like permease family 84 179 5.3E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS23415 9da65e7721300759adb4d99e60cf1f38 619 PIRSF PIRSF018968 1 617 1.5E-55 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS23100 66bd9a46759a95a90ed09fb46502da03 182 Pfam PF13302 Acetyltransferase (GNAT) domain 11 150 4.5E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS23100 66bd9a46759a95a90ed09fb46502da03 182 SUPERFAMILY SSF55729 6 174 1.65E-40 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS23100 66bd9a46759a95a90ed09fb46502da03 182 Gene3D G3DSA:3.40.630.30 2 182 1.6E-27 T 29-03-2018 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 ProSitePatterns PS01117 MarR-type HTH domain signature. 98 132 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 8.8E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 135 8.8E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 115 8.8E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 PRINTS PR00598 Bacterial regulatory protein MarR family signature 149 169 8.8E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 Pfam PF01047 MarR family 65 123 1.6E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 SUPERFAMILY SSF46785 26 172 2.26E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 SMART SM00347 51 159 1.2E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS17510 baad85ecc5b9dba423ae7201ca6de843 181 Gene3D G3DSA:1.10.10.10 15 179 5.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 Pfam PF00664 ABC transporter transmembrane region 20 288 1.4E-22 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 Pfam PF00005 ABC transporter 345 482 1.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 SUPERFAMILY SSF90123 1 313 4.58E-52 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 SUPERFAMILY SSF52540 325 542 1.11E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 357 370 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 Gene3D G3DSA:3.40.50.300 316 543 3.9E-61 T 29-03-2018 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 Gene3D G3DSA:1.20.1560.10 1 315 3.3E-45 T 29-03-2018 CSW12_RS09680 7adf75369bbda77bbbde024e57df8b45 544 SMART SM00382 353 528 3.1E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 Gene3D G3DSA:3.90.1170.10 2 139 1.5E-53 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 SUPERFAMILY SSF54686 1 136 3.66E-58 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.8E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.8E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.8E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.8E-41 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 6.9E-52 T 29-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.0E-62 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.056 T 29-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28020 e4cf20b16964edc7537e0e4e3f2c0454 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 29-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS10505 6639ec087908cf436800ab25f0b5c9cd 174 Gene3D G3DSA:3.40.630.30 1 140 1.9E-15 T 29-03-2018 CSW12_RS10505 6639ec087908cf436800ab25f0b5c9cd 174 Pfam PF13527 Acetyltransferase (GNAT) domain 4 132 3.7E-10 T 29-03-2018 CSW12_RS10505 6639ec087908cf436800ab25f0b5c9cd 174 SUPERFAMILY SSF55729 1 138 5.05E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS22440 559e694f023dfd574f875d4d78dbcef3 237 Pfam PF02517 CAAX protease self-immunity 144 232 1.5E-20 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS21220 dd9828a6b202f1c45c14e108290cd4cf 121 Pfam PF12438 Protein of unknown function (DUF3679) 16 70 2.9E-22 T 29-03-2018 IPR020534 Uncharacterised protein family YqxA CSW12_RS21220 dd9828a6b202f1c45c14e108290cd4cf 121 ProDom PD072942 YQXA ORF79 9 98 1.0E-44 T 29-03-2018 IPR020534 Uncharacterised protein family YqxA CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 SMART SM00382 41 233 8.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 Pfam PF00005 ABC transporter 33 184 3.8E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 3.6E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 9.7E-29 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 Gene3D G3DSA:3.40.50.300 2 321 5.5E-84 T 29-03-2018 CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS28600 4678e0f4e526ff92ac73ca507b5875b7 321 SUPERFAMILY SSF52540 40 319 1.09E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 Gene3D G3DSA:3.50.50.60 6 265 5.6E-69 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 Pfam PF01134 Glucose inhibited division protein A 9 398 1.8E-172 T 29-03-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 SUPERFAMILY SSF51905 98 261 2.4E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 SUPERFAMILY SSF51905 7 67 2.4E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 SMART SM01228 545 616 6.0E-43 T 29-03-2018 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 4.7E-295 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 Pfam PF13932 GidA associated domain 401 615 3.3E-79 T 29-03-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 29-03-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.588 T 29-03-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.2E-5 T 29-03-2018 CSW12_RS27280 b7222066a32c834877725f6ba24b0de9 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 1.2E-5 T 29-03-2018 CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 SUPERFAMILY SSF56112 6 402 1.15E-83 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 Gene3D G3DSA:3.30.200.20 1 108 4.6E-33 T 29-03-2018 CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 409 175.141 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 Pfam PF01636 Phosphotransferase enzyme family 34 271 2.4E-12 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 35 398 2.4E-98 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 PIRSF PIRSF031134 2 405 1.2E-163 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CSW12_RS00560 d22d59ecafc4162a4982d232d92e3705 409 Gene3D G3DSA:3.90.1200.10 109 384 9.8E-14 T 29-03-2018 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 PIRSF PIRSF006809 1 415 1.4E-151 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 Gene3D G3DSA:3.40.50.300 157 422 1.7E-27 T 29-03-2018 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 7 355 5.5E-145 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 Pfam PF01926 50S ribosome-binding GTPase 200 318 9.6E-19 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 3.3E-33 T 29-03-2018 IPR025121 GTPase HflX, N-terminal CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 SUPERFAMILY SSF52540 197 364 3.61E-36 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 1.6E-30 T 29-03-2018 IPR032305 GTP-binding protein, middle domain CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 8.6E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 8.6E-8 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS09260 6a22bd8c560b0a7fb1381e8ca53beef7 425 Hamap MF_00900 GTPase HflX [hflX]. 27 385 45.095 T 29-03-2018 IPR016496 GTPase HflX GO:0005525 CSW12_RS26530 cf688f0a376bfe048d570ebd2ddde411 317 Pfam PF03851 UV-endonuclease UvdE 5 273 5.6E-122 T 29-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 CSW12_RS26530 cf688f0a376bfe048d570ebd2ddde411 317 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 302 2.3E-100 T 29-03-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 CSW12_RS26530 cf688f0a376bfe048d570ebd2ddde411 317 SUPERFAMILY SSF51658 83 256 7.69E-17 T 29-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CSW12_RS26530 cf688f0a376bfe048d570ebd2ddde411 317 Gene3D G3DSA:3.20.20.150 64 305 2.5E-22 T 29-03-2018 CSW12_RS26530 cf688f0a376bfe048d570ebd2ddde411 317 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 303 41.704 T 29-03-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 CSW12_RS17870 95ffa668c08ae65740bba4ec7d164d49 272 TIGRFAM TIGR00552 nadE: NAD+ synthetase 18 272 2.5E-81 T 29-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CSW12_RS17870 95ffa668c08ae65740bba4ec7d164d49 272 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 266 32.721 T 29-03-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CSW12_RS17870 95ffa668c08ae65740bba4ec7d164d49 272 Pfam PF02540 NAD synthase 23 263 2.2E-76 T 29-03-2018 IPR022310 NAD/GMP synthase CSW12_RS17870 95ffa668c08ae65740bba4ec7d164d49 272 Gene3D G3DSA:3.40.50.620 2 272 1.4E-65 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS17870 95ffa668c08ae65740bba4ec7d164d49 272 SUPERFAMILY SSF52402 3 271 8.87E-83 T 29-03-2018 CSW12_RS10720 545c3b2c85ec8121ba58e72da00d63b8 257 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 113 132 - T 29-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CSW12_RS10720 545c3b2c85ec8121ba58e72da00d63b8 257 Gene3D G3DSA:3.60.15.10 31 257 9.4E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10720 545c3b2c85ec8121ba58e72da00d63b8 257 Pfam PF00753 Metallo-beta-lactamase superfamily 69 223 3.3E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10720 545c3b2c85ec8121ba58e72da00d63b8 257 SUPERFAMILY SSF56281 46 256 3.8E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10720 545c3b2c85ec8121ba58e72da00d63b8 257 ProSitePatterns PS00744 Beta-lactamases class B signature 2. 189 201 - T 29-03-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CSW12_RS10720 545c3b2c85ec8121ba58e72da00d63b8 257 SMART SM00849 70 240 1.3E-22 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 161 182 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 Gene3D G3DSA:3.10.50.40 125 246 7.8E-40 T 29-03-2018 CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 SUPERFAMILY SSF54534 121 222 1.64E-33 T 29-03-2018 CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 Gene3D G3DSA:1.10.4030.10 23 124 1.5E-5 T 29-03-2018 CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 SUPERFAMILY SSF109998 28 162 5.1E-15 T 29-03-2018 IPR027304 Trigger factor/SurA domain CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 Hamap MF_01145 Foldase protein PrsA [prsA]. 4 279 21.737 T 29-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CSW12_RS13380 67a49fdd88427bbb606f852b05905b8a 280 Pfam PF13616 PPIC-type PPIASE domain 134 224 2.7E-28 T 29-03-2018 CSW12_RS08050 82aa572f7268125a3a88fff0cbce4ceb 301 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 3 283 3.3E-143 T 29-03-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG CSW12_RS08050 82aa572f7268125a3a88fff0cbce4ceb 301 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 281 1.5E-61 T 29-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CSW12_RS23130 80892200fb72f0c128e6b5dbdb155da8 304 SUPERFAMILY SSF53187 96 299 8.48E-36 T 29-03-2018 CSW12_RS23130 80892200fb72f0c128e6b5dbdb155da8 304 SMART SM00646 178 297 1.4E-11 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS23130 80892200fb72f0c128e6b5dbdb155da8 304 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 98 297 1.2E-43 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS23130 80892200fb72f0c128e6b5dbdb155da8 304 Gene3D G3DSA:3.40.630.40 77 304 2.4E-42 T 29-03-2018 CSW12_RS01125 4a9efd8eced2f13539fe59669812f855 526 Pfam PF00535 Glycosyl transferase family 2 15 123 2.5E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS01125 4a9efd8eced2f13539fe59669812f855 526 Pfam PF00535 Glycosyl transferase family 2 273 376 1.8E-11 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS01125 4a9efd8eced2f13539fe59669812f855 526 SUPERFAMILY SSF53448 271 430 2.6E-16 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01125 4a9efd8eced2f13539fe59669812f855 526 SUPERFAMILY SSF53448 10 193 4.93E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01125 4a9efd8eced2f13539fe59669812f855 526 Gene3D G3DSA:3.90.550.10 258 449 3.8E-13 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01125 4a9efd8eced2f13539fe59669812f855 526 Gene3D G3DSA:3.90.550.10 9 190 6.1E-28 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05975 0327ec3bd2770aec77c6909706cb1468 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 267 3.9E-15 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05975 0327ec3bd2770aec77c6909706cb1468 282 SUPERFAMILY SSF161098 3 270 9.35E-58 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05975 0327ec3bd2770aec77c6909706cb1468 282 Gene3D G3DSA:1.10.3720.10 5 280 2.3E-45 T 29-03-2018 CSW12_RS01235 a558af6c83f942f5d35b4c222077052f 176 SUPERFAMILY SSF159234 3 171 7.59E-31 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS01235 a558af6c83f942f5d35b4c222077052f 176 Hamap MF_01568 UPF0374 protein . 1 175 51.707 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 CSW12_RS01235 a558af6c83f942f5d35b4c222077052f 176 PIRSF PIRSF028345 1 176 1.9E-80 T 29-03-2018 IPR016882 Uncharacterised protein family UPF0374 CSW12_RS01235 a558af6c83f942f5d35b4c222077052f 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 6.4E-17 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS01235 a558af6c83f942f5d35b4c222077052f 176 Gene3D G3DSA:2.40.380.10 12 171 8.7E-31 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS15580 fb9c1684c5be6482c2c45ad05dbd4031 292 Pfam PF12844 Helix-turn-helix domain 7 67 8.9E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15580 fb9c1684c5be6482c2c45ad05dbd4031 292 SMART SM00530 9 63 8.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15580 fb9c1684c5be6482c2c45ad05dbd4031 292 Gene3D G3DSA:1.10.260.40 2 97 3.6E-19 T 29-03-2018 CSW12_RS15580 fb9c1684c5be6482c2c45ad05dbd4031 292 SUPERFAMILY SSF48452 134 278 6.5E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS15580 fb9c1684c5be6482c2c45ad05dbd4031 292 Gene3D G3DSA:1.25.40.10 98 292 2.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS15580 fb9c1684c5be6482c2c45ad05dbd4031 292 SUPERFAMILY SSF47413 5 65 2.28E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02700 05ffac6ceef35e4188eb5aeb67ed5a68 103 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 22 92 1.1E-12 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CSW12_RS02700 05ffac6ceef35e4188eb5aeb67ed5a68 103 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 13 103 4.1E-38 T 29-03-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 CSW12_RS21390 99407c1808609e6c699aa1980701a21b 200 Gene3D G3DSA:3.40.50.1240 1 197 1.3E-23 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS21390 99407c1808609e6c699aa1980701a21b 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 177 5.2E-12 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS21390 99407c1808609e6c699aa1980701a21b 200 SMART SM00855 2 166 2.9E-6 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS21390 99407c1808609e6c699aa1980701a21b 200 SUPERFAMILY SSF53254 1 193 2.08E-20 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 332 2.4E-123 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 Gene3D G3DSA:3.30.390.10 1 136 1.2E-28 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 SUPERFAMILY SSF54826 2 126 5.79E-33 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 125 5.4E-13 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 Pfam PF13378 Enolase C-terminal domain-like 145 343 3.3E-40 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 43.608 T 29-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 SUPERFAMILY SSF51604 114 360 3.8E-59 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 SMART SM00922 142 234 5.2E-20 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CSW12_RS23995 9c5380c8379db501bbc7dafc71724c06 368 Gene3D G3DSA:3.20.20.120 137 342 2.6E-54 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS22135 249740c938d4915ce8e2bcbdf2e06dca 408 Gene3D G3DSA:3.40.190.10 47 158 3.6E-11 T 29-03-2018 CSW12_RS22135 249740c938d4915ce8e2bcbdf2e06dca 408 Pfam PF12698 ABC-2 family transporter protein 20 380 4.5E-44 T 29-03-2018 CSW12_RS26390 b93254b36f362fecc82627403627513c 165 Gene3D G3DSA:2.70.70.10 8 164 7.7E-61 T 29-03-2018 CSW12_RS26390 b93254b36f362fecc82627403627513c 165 SUPERFAMILY SSF51261 8 153 3.66E-57 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS26390 b93254b36f362fecc82627403627513c 165 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 17 137 2.2E-48 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CSW12_RS26390 b93254b36f362fecc82627403627513c 165 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 79 91 - T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CSW12_RS26390 b93254b36f362fecc82627403627513c 165 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 16 139 7.1E-54 T 29-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 5.5E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 Gene3D G3DSA:3.30.565.10 269 418 1.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 SUPERFAMILY SSF47384 198 267 2.75E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 SUPERFAMILY SSF55874 258 415 3.01E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 265 1.2E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 Gene3D G3DSA:1.10.287.130 191 265 3.0E-16 T 29-03-2018 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 SMART SM00388 203 269 2.8E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 413 8.4E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 SMART SM00387 309 415 2.4E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14515 4e8142688d1b6fe05a80f766ffbc2fd7 422 Pfam PF07694 5TMR of 5TMR-LYT 23 179 1.3E-21 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CSW12_RS14105 aaf573d029e2047cea48c7af9e4b166c 174 Pfam PF08877 MepB protein 36 157 9.8E-49 T 29-03-2018 IPR011235 MepB-like CSW12_RS14105 aaf573d029e2047cea48c7af9e4b166c 174 PIRSF PIRSF032285 9 174 2.6E-66 T 29-03-2018 IPR011235 MepB-like CSW12_RS01580 954ca76c442c91e814be840c868f1b84 273 Gene3D G3DSA:1.20.1270.30 14 82 0.11 T 29-03-2018 CSW12_RS01580 954ca76c442c91e814be840c868f1b84 273 Gene3D G3DSA:1.20.1270.30 162 191 0.025 T 29-03-2018 CSW12_RS01580 954ca76c442c91e814be840c868f1b84 273 Gene3D G3DSA:1.20.1270.30 192 259 0.0075 T 29-03-2018 CSW12_RS01580 954ca76c442c91e814be840c868f1b84 273 Gene3D G3DSA:1.20.1270.30 130 161 0.0057 T 29-03-2018 CSW12_RS00300 d6c5be6aa28268a9c84ce3caa4c89f09 438 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 43 418 1.2E-52 T 29-03-2018 IPR024455 Phage capsid CSW12_RS00300 d6c5be6aa28268a9c84ce3caa4c89f09 438 Pfam PF05065 Phage capsid family 152 419 1.2E-59 T 29-03-2018 IPR024455 Phage capsid CSW12_RS00300 d6c5be6aa28268a9c84ce3caa4c89f09 438 SUPERFAMILY SSF56563 148 418 4.18E-38 T 29-03-2018 CSW12_RS00300 d6c5be6aa28268a9c84ce3caa4c89f09 438 Gene3D G3DSA:3.30.2400.10 173 315 8.2E-16 T 29-03-2018 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 Pfam PF03466 LysR substrate binding domain 120 274 1.7E-26 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 SUPERFAMILY SSF46785 7 93 1.16E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 Gene3D G3DSA:3.40.190.10 98 176 1.7E-4 T 29-03-2018 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.1E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 Gene3D G3DSA:3.40.190.10 177 260 2.1E-23 T 29-03-2018 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.2E-7 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 SUPERFAMILY SSF53850 93 273 1.5E-26 T 29-03-2018 CSW12_RS22895 67eee4603b1b3fc187aa78cd6bc7f1e7 285 Gene3D G3DSA:1.10.10.10 7 97 2.1E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26460 a7609c4f982493499917170b10a4bb92 321 Gene3D G3DSA:3.30.540.10 157 321 6.1E-61 T 29-03-2018 CSW12_RS26460 a7609c4f982493499917170b10a4bb92 321 Gene3D G3DSA:3.30.540.10 1 156 2.2E-57 T 29-03-2018 CSW12_RS26460 a7609c4f982493499917170b10a4bb92 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 321 3.7E-155 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CSW12_RS26460 a7609c4f982493499917170b10a4bb92 321 PIRSF PIRSF004532 1 321 1.0E-151 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CSW12_RS26460 a7609c4f982493499917170b10a4bb92 321 SUPERFAMILY SSF56655 2 313 1.53E-112 T 29-03-2018 CSW12_RS26460 a7609c4f982493499917170b10a4bb92 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 310 1.1E-144 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CSW12_RS16800 1e5c1ef2b4c18b45061f32e8b6ac64bd 195 SUPERFAMILY SSF52833 37 195 1.41E-40 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS16800 1e5c1ef2b4c18b45061f32e8b6ac64bd 195 Gene3D G3DSA:3.40.30.10 27 195 1.1E-32 T 29-03-2018 CSW12_RS16800 1e5c1ef2b4c18b45061f32e8b6ac64bd 195 Pfam PF02630 SCO1/SenC 25 176 5.9E-39 T 29-03-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 SUPERFAMILY SSF161070 4 486 1.83E-143 T 29-03-2018 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 9.7E-25 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 9.7E-25 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 311 330 9.7E-25 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 9.7E-25 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS07315 25796d2a0c4372753e15b5d23fb0cfaf 508 Pfam PF00209 Sodium:neurotransmitter symporter family 124 482 3.4E-78 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS27675 0370dfbde04549ca1cff733651dd8124 180 SUPERFAMILY SSF53271 4 178 1.15E-59 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS27675 0370dfbde04549ca1cff733651dd8124 180 Pfam PF00156 Phosphoribosyl transferase domain 15 160 1.2E-24 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS27675 0370dfbde04549ca1cff733651dd8124 180 Gene3D G3DSA:3.40.50.2020 1 180 7.4E-48 T 29-03-2018 CSW12_RS27675 0370dfbde04549ca1cff733651dd8124 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 3.9E-69 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 Hamap MF_01670 Methylmalonate semialdehyde dehydrogenase [acylating] [iolA]. 3 485 74.009 T 29-03-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 Gene3D G3DSA:3.40.309.10 268 463 5.7E-62 T 29-03-2018 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 Gene3D G3DSA:3.40.605.10 1 267 6.1E-89 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 9 485 4.6E-181 T 29-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 Pfam PF00171 Aldehyde dehydrogenase family 17 481 4.7E-150 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS16265 69bd39b448f2acb11ea0f9f9560fb15f 486 SUPERFAMILY SSF53720 4 485 6.28E-151 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 PIRSF PIRSF001589 72 595 3.0E-51 T 29-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 SUPERFAMILY SSF56235 59 213 7.03E-19 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 Gene3D G3DSA:3.60.20.10 48 212 4.9E-19 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 SUPERFAMILY SSF52402 208 377 1.02E-31 T 29-03-2018 CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 SUPERFAMILY SSF52402 446 535 1.02E-31 T 29-03-2018 CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 Pfam PF13537 Glutamine amidotransferase domain 72 153 3.5E-14 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 Gene3D G3DSA:3.40.50.620 213 593 3.2E-35 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS10835 814e725d90bc494415eb853f4767dc25 596 Pfam PF00733 Asparagine synthase 232 586 1.7E-34 T 29-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 SMART SM00418 9 88 2.7E-15 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 SUPERFAMILY SSF46785 5 86 1.32E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 Pfam PF12840 Helix-turn-helix domain 10 68 4.5E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 5.1E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 5.1E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 5.1E-7 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 Gene3D G3DSA:1.10.10.10 87 224 0.0031 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12275 fc97d88aea417e2a33905da968d4ca92 235 Gene3D G3DSA:1.10.10.10 3 86 5.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 30.212 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Gene3D G3DSA:2.40.50.140 2 64 2.3E-19 T 29-03-2018 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 SUPERFAMILY SSF46929 157 200 3.01E-10 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Gene3D G3DSA:1.10.150.20 65 116 1.9E-12 T 29-03-2018 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Gene3D G3DSA:1.10.150.20 117 163 0.65 T 29-03-2018 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 SMART SM00278 106 125 2.1 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 SMART SM00278 71 90 0.38 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 SUPERFAMILY SSF50249 1 61 6.28E-15 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 4 201 2.4E-58 T 29-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Pfam PF14520 Helix-hairpin-helix domain 70 127 3.6E-15 T 29-03-2018 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 SUPERFAMILY SSF47781 63 135 1.6E-20 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Gene3D G3DSA:1.10.8.10 164 200 4.5E-10 T 29-03-2018 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Pfam PF01330 RuvA N terminal domain 2 60 7.0E-19 T 29-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CSW12_RS21745 c5a9557b87ce8c6aee2908aa73b68b13 205 Pfam PF07499 RuvA, C-terminal domain 158 200 6.6E-12 T 29-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.270.10 751 845 4.6E-11 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF00562 RNA polymerase Rpb2, domain 6 675 1068 2.7E-162 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.270.10 846 1054 4.8E-75 T 29-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF10385 RNA polymerase beta subunit external 1 domain 546 613 2.4E-23 T 29-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 SUPERFAMILY SSF64484 366 1156 0.0 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 SUPERFAMILY SSF64484 13 288 0.0 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04563 RNA polymerase beta subunit 28 453 5.6E-31 T 29-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1100.10 20 240 5.6E-59 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1100.10 329 603 1.1E-82 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1100.10 604 670 6.8E-13 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1146 12.593 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:3.90.1800.10 1071 1115 8.0E-12 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 373 409 4.7E-6 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 6.5E-27 T 29-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 895 0.0 T 29-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 ProSitePatterns PS01166 RNA polymerases beta chain signature. 921 933 - T 29-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04560 RNA polymerase Rpb2, domain 7 1070 1145 1.3E-27 T 29-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Gene3D G3DSA:2.40.50.100 672 750 1.7E-23 T 29-03-2018 CSW12_RS27940 bb95a0509f76cfa76bff0f777fcde802 1177 Pfam PF04565 RNA polymerase Rpb2, domain 3 468 536 1.3E-30 T 29-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 1.4E-11 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 6.0E-117 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 4.2E-23 T 29-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 Hamap MF_00564 Ribonuclease PH [rph]. 1 238 47.284 T 29-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 29-03-2018 IPR018336 Ribonuclease PH, conserved site CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 SUPERFAMILY SSF54211 1 140 1.52E-43 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 Gene3D G3DSA:3.30.230.70 1 240 5.4E-58 T 29-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS22060 be4444789914abbb38b2a2c9e0b4fef8 245 SUPERFAMILY SSF55666 151 238 3.14E-25 T 29-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 PIRSF PIRSF000193 1 265 2.7E-65 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 Gene3D G3DSA:3.40.50.720 1 156 9.3E-18 T 29-03-2018 CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 SUPERFAMILY SSF51735 2 159 3.9E-22 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 260 5.9E-17 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 5.9E-15 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 Gene3D G3DSA:1.10.3730.10 157 267 5.3E-20 T 29-03-2018 CSW12_RS21270 f05828d317d951c58d4cd8bd2ae45b51 275 SUPERFAMILY SSF48179 158 262 1.02E-19 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS27140 d50b68545d4aadb3728c0102bf3a4f4e 159 SUPERFAMILY SSF75217 2 157 4.58E-60 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CSW12_RS27140 d50b68545d4aadb3728c0102bf3a4f4e 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 1.4E-56 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS27140 d50b68545d4aadb3728c0102bf3a4f4e 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.048 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS27140 d50b68545d4aadb3728c0102bf3a4f4e 159 PIRSF PIRSF004505 1 159 6.0E-52 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS27140 d50b68545d4aadb3728c0102bf3a4f4e 159 Gene3D G3DSA:3.40.1280.10 1 159 9.6E-60 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CSW12_RS27140 d50b68545d4aadb3728c0102bf3a4f4e 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 1.9E-67 T 29-03-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS07915 4d829e4648a34cf3b200af2b6ab7aa08 42 Pfam PF13790 SR1 protein 1 37 3.1E-19 T 29-03-2018 IPR025236 SR1 protein CSW12_RS16540 64881a7689d15b7be35f0264862817de 180 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 180 25.135 T 29-03-2018 IPR023522 Chromosome-anchoring protein RacA CSW12_RS16540 64881a7689d15b7be35f0264862817de 180 SUPERFAMILY SSF58064 67 130 2.39E-5 T 29-03-2018 CSW12_RS16540 64881a7689d15b7be35f0264862817de 180 Gene3D G3DSA:1.10.1660.10 2 153 1.2E-11 T 29-03-2018 CSW12_RS25790 8bc245dda3f3715a33ff4dfb1adefed6 123 SUPERFAMILY SSF56276 5 117 1.9E-39 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CSW12_RS25790 8bc245dda3f3715a33ff4dfb1adefed6 123 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 5 115 1.0E-42 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CSW12_RS25790 8bc245dda3f3715a33ff4dfb1adefed6 123 Pfam PF02675 S-adenosylmethionine decarboxylase 9 115 8.6E-35 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CSW12_RS25790 8bc245dda3f3715a33ff4dfb1adefed6 123 Gene3D G3DSA:3.60.90.10 1 123 8.3E-42 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CSW12_RS25790 8bc245dda3f3715a33ff4dfb1adefed6 123 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 3 119 29.578 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 Pfam PF08402 TOBE domain 282 357 6.2E-8 T 29-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 SUPERFAMILY SSF52540 4 243 2.26E-85 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 SMART SM00382 29 212 4.5E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 SUPERFAMILY SSF50331 237 365 2.07E-28 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 Gene3D G3DSA:2.40.50.100 240 294 1.4E-11 T 29-03-2018 CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 Gene3D G3DSA:2.40.50.140 295 350 1.1E-15 T 29-03-2018 CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 Pfam PF00005 ABC transporter 21 162 2.0E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS07650 e24f462619ecb33c40754af0a9dad2d9 366 Gene3D G3DSA:3.40.50.300 1 235 3.1E-72 T 29-03-2018 CSW12_RS16370 a950960b9944240313966ffeaa086531 332 Gene3D G3DSA:3.20.20.80 2 189 4.3E-44 T 29-03-2018 CSW12_RS16370 a950960b9944240313966ffeaa086531 332 Pfam PF01183 Glycosyl hydrolases family 25 5 168 6.4E-22 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CSW12_RS16370 a950960b9944240313966ffeaa086531 332 SUPERFAMILY SSF51445 4 187 1.19E-40 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 SMART SM00267 474 645 5.0E-63 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 483 644 9.2E-39 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 Gene3D G3DSA:3.30.70.270 488 652 2.2E-56 T 29-03-2018 CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 Gene3D G3DSA:3.30.450.20 325 487 1.2E-16 T 29-03-2018 CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 SMART SM00091 361 427 6.0E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 Pfam PF00990 Diguanylate cyclase, GGDEF domain 485 640 2.4E-47 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 SUPERFAMILY SSF55785 354 472 8.38E-13 T 29-03-2018 IPR000014 PAS domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 Gene3D G3DSA:3.20.20.450 653 912 5.9E-97 T 29-03-2018 IPR001633 EAL domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 Pfam PF00563 EAL domain 661 896 9.5E-70 T 29-03-2018 IPR001633 EAL domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 SUPERFAMILY SSF141868 660 908 1.44E-87 T 29-03-2018 IPR001633 EAL domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 359 480 3.0E-13 T 29-03-2018 IPR000014 PAS domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 SMART SM00052 655 901 2.0E-109 T 29-03-2018 IPR001633 EAL domain CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 SUPERFAMILY SSF55073 491 647 8.63E-48 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS10185 47cb7cb291efdc6767c6a6f89c2a4949 912 Pfam PF13426 PAS domain 371 472 7.5E-8 T 29-03-2018 IPR000014 PAS domain CSW12_RS11370 bc38d41159f62e8e4e9878c653b8fd3e 275 Pfam PF04231 Endonuclease I 59 268 8.1E-45 T 29-03-2018 IPR007346 Endonuclease I GO:0004518 CSW12_RS11370 bc38d41159f62e8e4e9878c653b8fd3e 275 SUPERFAMILY SSF54060 57 268 8.0E-60 T 29-03-2018 CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 28.071 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 177 2.4E-50 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 SUPERFAMILY SSF56420 2 178 1.26E-61 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 Pfam PF01327 Polypeptide deformylase 4 171 1.0E-45 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 PIRSF PIRSF004749 2 184 1.2E-47 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 Gene3D G3DSA:3.90.45.10 3 184 4.0E-55 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 PRINTS PR01576 Peptide deformylase signature 121 139 6.6E-33 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 PRINTS PR01576 Peptide deformylase signature 47 76 6.6E-33 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 PRINTS PR01576 Peptide deformylase signature 140 169 6.6E-33 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS07870 928eee0bf8d157c04880d7be548a9c96 184 PRINTS PR01576 Peptide deformylase signature 108 119 6.6E-33 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 SMART SM00829 16 336 6.0E-11 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 SUPERFAMILY SSF51735 117 288 4.66E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 Gene3D G3DSA:3.90.180.10 1 159 9.3E-38 T 29-03-2018 CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 Gene3D G3DSA:3.40.50.720 160 258 2.2E-16 T 29-03-2018 CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 93 2.4E-6 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 Pfam PF13602 Zinc-binding dehydrogenase 195 336 5.8E-22 T 29-03-2018 CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 SUPERFAMILY SSF50129 12 139 3.2E-29 T 29-03-2018 IPR011032 GroES-like CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 339 1.1E-142 T 29-03-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CSW12_RS10650 eb093aa74c358f3ee418232054aa279d 339 Gene3D G3DSA:3.90.180.10 259 338 0.0075 T 29-03-2018 CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 4.4E-192 T 29-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 PIRSF PIRSF005572 20 404 7.4E-56 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 Gene3D G3DSA:3.40.640.10 33 280 1.2E-61 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 SUPERFAMILY SSF53383 2 398 1.43E-133 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 Pfam PF00266 Aminotransferase class-V 23 391 1.6E-164 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS24710 725589aa4c2127a836fd8aace93e0b33 406 Gene3D G3DSA:3.90.1150.10 281 398 3.8E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS16000 8ece0f7001b5e69c1d1b6b942ebf60a4 60 Pfam PF13213 Protein of unknown function (DUF4021) 9 51 1.5E-25 T 29-03-2018 IPR025094 Protein of unknown function DUF4021 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 SMART SM00437 262 549 2.9E-83 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Pfam PF01751 Toprim domain 5 134 1.6E-16 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 3.8E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 512 526 3.8E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 3.8E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 3.8E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 3.8E-25 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Gene3D G3DSA:2.70.20.10 348 476 8.6E-26 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 SMART SM00436 126 216 1.1E-35 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 SMART SM00493 3 126 3.0E-18 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Pfam PF01131 DNA topoisomerase 152 583 7.5E-117 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Gene3D G3DSA:3.40.50.140 3 154 3.8E-43 T 29-03-2018 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 SUPERFAMILY SSF56712 3 598 6.41E-176 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 727 3.0E-260 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 638 72.175 T 29-03-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Gene3D G3DSA:3.30.65.10 646 695 0.39 T 29-03-2018 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Gene3D G3DSA:3.30.65.10 595 645 8.4E-7 T 29-03-2018 CSW12_RS00765 5e7697b2f55a20b5f1cd502f9b89aa7c 729 Gene3D G3DSA:1.10.460.10 159 336 1.5E-37 T 29-03-2018 CSW12_RS12965 278e02e69cda3050d8eaa6e1bc159d3a 275 Pfam PF01522 Polysaccharide deacetylase 68 175 3.4E-27 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS12965 278e02e69cda3050d8eaa6e1bc159d3a 275 Gene3D G3DSA:3.20.20.370 30 262 7.9E-46 T 29-03-2018 CSW12_RS12965 278e02e69cda3050d8eaa6e1bc159d3a 275 SUPERFAMILY SSF88713 65 264 1.68E-52 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Gene3D G3DSA:2.40.110.10 144 237 2.8E-33 T 29-03-2018 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 368 387 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Gene3D G3DSA:1.10.540.10 2 143 5.5E-30 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 237 2.9E-24 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 SUPERFAMILY SSF56645 20 260 1.19E-73 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Gene3D G3DSA:1.20.140.10 424 541 2.5E-4 T 29-03-2018 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Gene3D G3DSA:1.20.140.10 238 423 6.5E-53 T 29-03-2018 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 409 6.7E-39 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 141 9.7E-27 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS16275 bb236675862a6116fb045b70037efad8 569 SUPERFAMILY SSF47203 254 419 8.05E-47 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS28820 68b5a84f058c084d09b1eb7ce94c0f92 145 Pfam PF00583 Acetyltransferase (GNAT) family 14 121 1.1E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS28820 68b5a84f058c084d09b1eb7ce94c0f92 145 SUPERFAMILY SSF55729 1 135 5.15E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS28820 68b5a84f058c084d09b1eb7ce94c0f92 145 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 141 2.5E-45 T 29-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CSW12_RS28820 68b5a84f058c084d09b1eb7ce94c0f92 145 Gene3D G3DSA:3.40.630.30 1 145 1.1E-34 T 29-03-2018 CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 Pfam PF00772 DnaB-like helicase N terminal domain 7 102 1.8E-19 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 Gene3D G3DSA:1.10.860.10 2 144 9.1E-23 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 Pfam PF03796 DnaB-like helicase C terminal domain 171 428 2.1E-93 T 29-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 Gene3D G3DSA:3.40.50.300 153 431 7.8E-62 T 29-03-2018 CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 6 429 1.4E-124 T 29-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 SUPERFAMILY SSF52540 169 423 4.16E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03960 79328829b33dfe9836556399b1f4d41b 431 SUPERFAMILY SSF48024 6 105 1.96E-20 T 29-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 278 358 1.4E-6 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 Gene3D G3DSA:3.40.710.10 27 309 1.1E-50 T 29-03-2018 CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 SUPERFAMILY SSF56601 13 276 2.39E-65 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 39 261 8.2E-67 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 118 135 2.6E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 2.6E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS06935 89a72d5ad1ccba805e898c198c3a844a 386 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 145 158 2.6E-15 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS26910 5a521f7427af8950ab3ee4875fe58c70 170 Pfam PF03061 Thioesterase superfamily 25 97 3.0E-14 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS26910 5a521f7427af8950ab3ee4875fe58c70 170 SUPERFAMILY SSF54637 1 150 9.48E-43 T 29-03-2018 IPR029069 HotDog domain CSW12_RS26910 5a521f7427af8950ab3ee4875fe58c70 170 Gene3D G3DSA:3.10.129.10 2 159 2.4E-44 T 29-03-2018 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.8E-65 T 29-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 SUPERFAMILY SSF46906 67 140 3.79E-27 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 2.5E-31 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 SMART SM00649 9 140 2.3E-87 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 Gene3D G3DSA:1.10.10.250 72 140 2.7E-24 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.612 T 29-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 29-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.9E-25 T 29-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 SUPERFAMILY SSF54747 3 72 1.83E-30 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-16 T 29-03-2018 CSW12_RS27915 3c6bbedfc44a957c95a670e0f61b8a91 141 Gene3D G3DSA:3.30.1550.10 3 71 2.6E-36 T 29-03-2018 IPR020784 Ribosomal protein L11, N-terminal CSW12_RS16490 7a5a7f4f94ce7cb494e0a09cee203cf6 299 Pfam PF13527 Acetyltransferase (GNAT) domain 130 241 4.7E-10 T 29-03-2018 CSW12_RS16490 7a5a7f4f94ce7cb494e0a09cee203cf6 299 Gene3D G3DSA:3.40.630.30 36 102 0.3 T 29-03-2018 CSW12_RS16490 7a5a7f4f94ce7cb494e0a09cee203cf6 299 Gene3D G3DSA:3.40.630.30 126 285 1.5E-19 T 29-03-2018 CSW12_RS16490 7a5a7f4f94ce7cb494e0a09cee203cf6 299 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 18 279 6.7E-103 T 29-03-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 CSW12_RS16490 7a5a7f4f94ce7cb494e0a09cee203cf6 299 SUPERFAMILY SSF55729 129 279 1.45E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 SUPERFAMILY SSF57716 142 192 7.13E-16 T 29-03-2018 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 Gene3D G3DSA:3.30.60.20 142 195 1.0E-18 T 29-03-2018 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.865 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 29-03-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 Gene3D G3DSA:3.40.50.300 7 141 5.9E-48 T 29-03-2018 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 Pfam PF00265 Thymidine kinase 8 187 5.5E-61 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 PIRSF PIRSF035805 5 195 1.7E-68 T 29-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CSW12_RS26440 bc6e614284f823f90c482bb133cf98f4 195 SUPERFAMILY SSF52540 8 142 1.24E-45 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 404 531 1.5E-20 T 29-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 Pfam PF01266 FAD dependent oxidoreductase 21 344 1.7E-51 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 371 381 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 SUPERFAMILY SSF51905 16 97 6.56E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 SUPERFAMILY SSF51905 157 237 6.56E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 SUPERFAMILY SSF54373 249 342 3.92E-11 T 29-03-2018 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 8.5E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 336 342 8.5E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 366 378 8.5E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 8.5E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 8.5E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 8.5E-31 T 29-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CSW12_RS04470 330dc28aaf03a6568e578fe4aee3aafa 560 Gene3D G3DSA:3.50.50.60 1 417 2.2E-61 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Gene3D G3DSA:1.10.10.60 590 649 1.6E-7 T 29-03-2018 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Pfam PF09382 RQC domain 400 509 8.0E-32 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Gene3D G3DSA:1.10.150.80 506 589 2.7E-25 T 29-03-2018 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Pfam PF00570 HRDC domain 517 582 3.7E-22 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 453 4.3E-145 T 29-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 5 583 3.6E-233 T 29-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Pfam PF16124 RecQ zinc-binding 336 396 4.1E-16 T 29-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SMART SM00956 404 507 1.1E-41 T 29-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SUPERFAMILY SSF52540 58 345 1.17E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Gene3D G3DSA:3.40.50.300 202 345 4.7E-34 T 29-03-2018 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Gene3D G3DSA:1.10.10.10 346 505 1.5E-47 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SMART SM00341 512 592 5.0E-20 T 29-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Pfam PF00270 DEAD/DEAH box helicase 21 181 1.0E-20 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SMART SM00490 243 324 5.5E-28 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SUPERFAMILY SSF47819 515 589 4.36E-24 T 29-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Gene3D G3DSA:3.40.50.300 2 201 3.0E-31 T 29-03-2018 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Pfam PF14493 Helix-turn-helix domain 614 701 1.5E-26 T 29-03-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SUPERFAMILY SSF46785 395 537 9.33E-36 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 Pfam PF00271 Helicase conserved C-terminal domain 218 323 3.3E-18 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS13610 70135cf9f07f8e351018fc4c30438c0c 705 SMART SM00487 14 211 1.8E-28 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 Gene3D G3DSA:1.10.10.10 4 73 6.4E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 208 38.744 T 29-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 Gene3D G3DSA:3.40.50.720 77 207 2.9E-17 T 29-03-2018 CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 SUPERFAMILY SSF51735 82 206 6.89E-30 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 SUPERFAMILY SSF46785 7 78 5.9E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 SMART SM00881 79 179 1.5E-19 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 Pfam PF02629 CoA binding domain 82 177 8.0E-31 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CSW12_RS28835 0876f7d72d7fb3ffce51d06e5edf7583 209 Pfam PF06971 Putative DNA-binding protein N-terminus 5 53 3.5E-18 T 29-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CSW12_RS00040 de4ab4c2a7bb3f87eeb3774bb6592c9d 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 4.0E-35 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00040 de4ab4c2a7bb3f87eeb3774bb6592c9d 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 3.1E-32 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00040 de4ab4c2a7bb3f87eeb3774bb6592c9d 84 Gene3D G3DSA:3.30.1280.10 2 79 4.6E-31 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00040 de4ab4c2a7bb3f87eeb3774bb6592c9d 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 21.493 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00040 de4ab4c2a7bb3f87eeb3774bb6592c9d 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 8.9E-32 T 29-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CSW12_RS00040 de4ab4c2a7bb3f87eeb3774bb6592c9d 84 SUPERFAMILY SSF82697 1 80 7.32E-29 T 29-03-2018 CSW12_RS21415 eb1e2344b379355689279c508dcd26f3 584 Gene3D G3DSA:1.10.800.10 2 320 7.5E-81 T 29-03-2018 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 CSW12_RS21415 eb1e2344b379355689279c508dcd26f3 584 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 201 290 2.4E-19 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CSW12_RS21415 eb1e2344b379355689279c508dcd26f3 584 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 22 146 8.2E-11 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CSW12_RS21415 eb1e2344b379355689279c508dcd26f3 584 SUPERFAMILY SSF56534 10 154 7.98E-83 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CSW12_RS21415 eb1e2344b379355689279c508dcd26f3 584 SUPERFAMILY SSF56534 200 332 7.98E-83 T 29-03-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 CSW12_RS05065 74f75ca3a8974c875952bc43912c2b71 116 SUPERFAMILY SSF160713 52 115 1.83E-19 T 29-03-2018 IPR023118 YqaI domain CSW12_RS05065 74f75ca3a8974c875952bc43912c2b71 116 Pfam PF09466 Hypothetical protein Yqai 75 107 5.6E-6 T 29-03-2018 IPR018474 Uncharacterised protein family YqaI CSW12_RS05065 74f75ca3a8974c875952bc43912c2b71 116 Gene3D G3DSA:3.30.40.30 56 116 1.6E-14 T 29-03-2018 CSW12_RS01055 c7bd3e138b9677b075516fd9be953c92 84 Gene3D G3DSA:2.40.50.100 6 76 1.7E-9 T 29-03-2018 CSW12_RS01055 c7bd3e138b9677b075516fd9be953c92 84 Pfam PF00364 Biotin-requiring enzyme 10 73 6.5E-5 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS01055 c7bd3e138b9677b075516fd9be953c92 84 SUPERFAMILY SSF51230 7 74 7.99E-7 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS00585 181e61b15541c42f19cf89723f45fe1d 305 Gene3D G3DSA:3.40.50.1980 149 304 7.0E-26 T 29-03-2018 CSW12_RS00585 181e61b15541c42f19cf89723f45fe1d 305 Gene3D G3DSA:3.40.50.1980 36 148 1.1E-23 T 29-03-2018 CSW12_RS00585 181e61b15541c42f19cf89723f45fe1d 305 Pfam PF01497 Periplasmic binding protein 70 278 1.8E-29 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS00585 181e61b15541c42f19cf89723f45fe1d 305 SUPERFAMILY SSF53807 38 298 3.92E-53 T 29-03-2018 CSW12_RS18270 a874a540205cbfccad60fa4f996c56e1 301 SUPERFAMILY SSF103481 186 289 5.23E-9 T 29-03-2018 CSW12_RS18270 a874a540205cbfccad60fa4f996c56e1 301 Pfam PF00892 EamA-like transporter family 11 140 4.3E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS18270 a874a540205cbfccad60fa4f996c56e1 301 Pfam PF00892 EamA-like transporter family 151 286 7.9E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS18270 a874a540205cbfccad60fa4f996c56e1 301 SUPERFAMILY SSF103481 43 143 1.2E-14 T 29-03-2018 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 Gene3D G3DSA:3.30.870.10 30 219 8.1E-29 T 29-03-2018 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 SUPERFAMILY SSF56024 200 391 2.36E-36 T 29-03-2018 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 Pfam PF13091 PLD-like domain 245 371 1.1E-26 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 Pfam PF13091 PLD-like domain 67 208 3.4E-10 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 49 401 1.0E-87 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 SMART SM00155 148 175 3.3 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 SMART SM00155 318 345 2.7E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 SUPERFAMILY SSF56024 30 216 3.53E-38 T 29-03-2018 CSW12_RS18830 98b78069d39b8b233fb41dcb5f022d85 405 Gene3D G3DSA:3.30.870.10 227 399 1.3E-29 T 29-03-2018 CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 SMART SM00065 26 177 0.0013 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 Pfam PF13185 GAF domain 25 168 5.1E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 SUPERFAMILY SSF55781 27 172 5.67E-19 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 Gene3D G3DSA:3.30.450.40 1 172 3.1E-22 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 Gene3D G3DSA:3.30.565.10 242 372 1.2E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 SUPERFAMILY SSF55874 252 371 1.31E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 Pfam PF07730 Histidine kinase 184 248 2.6E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS16655 f449933d4d90c689541d8bdde8174103 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 286 371 5.7E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01940 dd527e2c540bb1221e2efd49216b9f66 317 Pfam PF13280 WYL domain 139 307 8.1E-26 T 29-03-2018 IPR026881 WYL domain CSW12_RS01940 dd527e2c540bb1221e2efd49216b9f66 317 Pfam PF08279 HTH domain 6 61 6.3E-16 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS01940 dd527e2c540bb1221e2efd49216b9f66 317 PIRSF PIRSF016838 2 317 8.8E-19 T 29-03-2018 IPR028349 Protein PafC CSW12_RS01940 dd527e2c540bb1221e2efd49216b9f66 317 Gene3D G3DSA:1.10.10.10 1 63 7.5E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01940 dd527e2c540bb1221e2efd49216b9f66 317 SUPERFAMILY SSF46785 3 60 9.99E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19655 838e2afd1fc9ba4a28fbee277b809614 188 Gene3D G3DSA:3.40.50.300 33 187 3.2E-13 T 29-03-2018 CSW12_RS19655 838e2afd1fc9ba4a28fbee277b809614 188 SUPERFAMILY SSF52540 34 186 7.97E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26125 143c32273795805c4170207adfdaebca 371 Pfam PF13535 ATP-grasp domain 135 274 3.6E-14 T 29-03-2018 CSW12_RS26125 143c32273795805c4170207adfdaebca 371 Gene3D G3DSA:3.30.470.20 168 298 3.1E-11 T 29-03-2018 CSW12_RS26125 143c32273795805c4170207adfdaebca 371 Gene3D G3DSA:3.40.50.20 1 114 6.3E-15 T 29-03-2018 CSW12_RS26125 143c32273795805c4170207adfdaebca 371 Gene3D G3DSA:3.30.1490.20 118 167 1.6E-10 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS26125 143c32273795805c4170207adfdaebca 371 SUPERFAMILY SSF56059 89 309 3.35E-28 T 29-03-2018 CSW12_RS26125 143c32273795805c4170207adfdaebca 371 SUPERFAMILY SSF52440 3 69 6.91E-6 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS13495 a166053c4195fad86c0b0867a6658392 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 8 59 1.3E-11 T 29-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 SUPERFAMILY SSF55347 184 487 1.28E-103 T 29-03-2018 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 7 189 2.6E-63 T 29-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 PIRSF PIRSF000110 1 490 1.4E-190 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 Gene3D G3DSA:3.30.360.10 191 489 2.6E-116 T 29-03-2018 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 Gene3D G3DSA:3.40.50.720 1 190 1.6E-69 T 29-03-2018 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 486 1.4E-104 T 29-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 SUPERFAMILY SSF51735 2 185 3.94E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 487 5.5E-178 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 3 488 80.367 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 2.1E-44 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 2.1E-44 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 2.1E-44 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 2.1E-44 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS11010 6b5699d31bbb83f83f69fd62de353468 494 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 2.1E-44 T 29-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 Gene3D G3DSA:3.40.50.2300 2 126 9.1E-33 T 29-03-2018 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 Pfam PF00072 Response regulator receiver domain 5 116 2.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 2.4E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 SUPERFAMILY SSF46894 150 207 8.5E-16 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 SMART SM00448 3 115 1.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 SUPERFAMILY SSF52172 1 131 7.4E-33 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 1.9E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 1.9E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 1.9E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 Gene3D G3DSA:1.10.10.10 127 211 2.7E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18855 52f2200b1c4577bc7ec1b4edee9e1f7e 212 SMART SM00421 149 206 1.7E-17 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Pfam PF00989 PAS fold 239 340 1.2E-11 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Pfam PF00989 PAS fold 119 219 4.6E-14 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 121 228 1.6E-15 T 29-03-2018 IPR000014 PAS domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 236 350 5.8E-17 T 29-03-2018 IPR000014 PAS domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Gene3D G3DSA:3.40.50.20 1 92 2.2E-9 T 29-03-2018 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 393 406 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Gene3D G3DSA:3.40.50.300 362 541 2.1E-28 T 29-03-2018 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Gene3D G3DSA:3.30.450.20 100 230 9.0E-20 T 29-03-2018 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Gene3D G3DSA:3.30.450.20 231 360 6.1E-17 T 29-03-2018 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Pfam PF00158 Sigma-54 interaction domain 369 537 6.1E-67 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Gene3D G3DSA:1.10.8.60 542 609 1.6E-20 T 29-03-2018 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SUPERFAMILY SSF46689 583 683 2.82E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 456 471 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SUPERFAMILY SSF52540 368 608 6.63E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SMART SM00091 237 302 1.0E-6 T 29-03-2018 IPR000014 PAS domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SMART SM00091 118 184 6.5E-12 T 29-03-2018 IPR000014 PAS domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SUPERFAMILY SSF55785 112 216 1.05E-16 T 29-03-2018 IPR000014 PAS domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 665 685 6.9E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 665 6.9E-7 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Gene3D G3DSA:1.10.10.60 610 683 1.1E-15 T 29-03-2018 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SUPERFAMILY SSF55785 236 336 3.14E-15 T 29-03-2018 IPR000014 PAS domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SUPERFAMILY SSF51735 1 100 2.23E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 Pfam PF02954 Bacterial regulatory protein, Fis family 643 682 8.4E-13 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 SMART SM00382 389 533 1.9E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS20410 99f4ab4bfe928a143a2bbef3d85b06af 690 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 583 592 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1667 1802 2.7E-20 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 4578 4714 8.7E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 4443 4577 2.6E-16 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1141 1277 9.8E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 2871 3000 6.9E-19 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1406 1539 2.9E-19 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1011 1140 2.7E-14 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1803 1940 1.8E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 2732 2870 2.2E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 3135 3270 1.3E-20 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 483 619 2.2E-18 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1278 1405 2.2E-13 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 2079 2214 4.7E-20 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1941 2078 2.7E-11 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 620 747 3.7E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 2476 2602 3.6E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 3925 4055 6.2E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4582 4634 2.3E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2607 2659 3.1E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2347 2399 2.4E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4714 4765 4.8E-14 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4193 4245 4.3E-15 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4450 4501 4.8E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1542 1594 2.0E-15 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3137 3189 3.1E-20 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 488 540 2.9E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 752 804 2.4E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3665 3717 1.6E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1410 1461 3.4E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3401 3453 2.2E-15 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3929 3981 6.2E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1278 1330 8.9E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3003 3054 7.5E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3533 3584 1.2E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3797 3849 1.9E-14 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4846 4897 1.7E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2215 2267 8.4E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1954 1993 3.1E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2083 2134 1.8E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1146 1197 9.9E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2871 2922 5.6E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1674 1726 1.1E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2479 2531 2.3E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1014 1066 3.0E-14 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2739 2790 1.7E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1806 1857 1.9E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 620 671 2.5E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4061 4112 8.2E-11 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 356 408 1.7E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 4326 4370 8.8E-11 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 883 935 7.4E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3271 3321 6.2E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 3271 3394 1.4E-13 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 1540 1665 1.3E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 3658 3788 5.7E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 4715 4825 9.6E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 748 875 5.2E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 4056 4186 1.4E-12 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.1580 3789 3924 1.6E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.1580 3001 3134 2.8E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.1580 2215 2343 8.3E-18 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3402 3486 2.1E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3797 3890 6.1E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 1672 1761 1.0E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 1144 1233 1.9E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3005 3087 9.4E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2479 2564 2.2E-11 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3533 3620 1.8E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 4712 4804 2.2E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 4450 4567 1.1E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 4060 4148 6.7E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 619 710 3.3E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2738 2823 1.5E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2347 2436 6.5E-12 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 355 450 2.7E-12 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 487 576 1.7E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 1541 1636 1.7E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3663 3754 3.7E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 1013 1102 1.9E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3272 3359 1.1E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2214 2298 8.4E-12 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 1805 1895 1.5E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2083 2167 2.2E-12 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 4193 4286 1.2E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 4844 4942 5.3E-6 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 3136 3232 7.2E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 4582 4670 7.9E-9 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 750 844 8.8E-14 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2870 2950 8.5E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 881 968 1.3E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 1409 1496 2.3E-7 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Pfam PF01345 Domain of unknown function DUF11 2611 2694 6.5E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 SUPERFAMILY SSF49401 3146 3236 8.2E-5 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 SUPERFAMILY SSF49401 3408 3502 2.73E-5 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.10 4187 4309 4.2E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.10 2344 2470 3.6E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 4839 4969 5.9E-15 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 2603 2727 5.7E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 3526 3651 4.7E-16 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 3395 3520 3.3E-16 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 349 477 2.9E-18 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.740 876 1010 7.1E-17 T 29-03-2018 CSW12_RS19620 f7715acc6aceb5b34486553d76bcd154 5010 Gene3D G3DSA:2.60.40.1220 4329 4423 9.9E-13 T 29-03-2018 CSW12_RS14890 5cde5ba3f32c74c046c61f7219e2bfff 159 Gene3D G3DSA:3.30.530.20 3 159 1.2E-20 T 29-03-2018 IPR023393 START-like domain CSW12_RS14890 5cde5ba3f32c74c046c61f7219e2bfff 159 SUPERFAMILY SSF55961 2 153 3.85E-32 T 29-03-2018 CSW12_RS14890 5cde5ba3f32c74c046c61f7219e2bfff 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 127 4.3E-10 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CSW12_RS24540 adab0c9507a40a5a27752096febeef79 292 SUPERFAMILY SSF81301 60 107 5.23E-7 T 29-03-2018 CSW12_RS24540 adab0c9507a40a5a27752096febeef79 292 Gene3D G3DSA:3.30.460.10 30 230 1.7E-12 T 29-03-2018 CSW12_RS24540 adab0c9507a40a5a27752096febeef79 292 Pfam PF13427 Domain of unknown function (DUF4111) 181 268 2.4E-5 T 29-03-2018 IPR025184 Domain of unknown function DUF4111 CSW12_RS24540 adab0c9507a40a5a27752096febeef79 292 Pfam PF01909 Nucleotidyltransferase domain 52 107 6.0E-5 T 29-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 SUPERFAMILY SSF53223 3 101 3.8E-37 T 29-03-2018 CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 116 209 4.8E-12 T 29-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 275 6.7E-94 T 29-03-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 273 36.433 T 29-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 1.3E-32 T 29-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 SUPERFAMILY SSF51735 102 274 1.38E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 Gene3D G3DSA:3.40.50.10860 1 111 4.6E-47 T 29-03-2018 CSW12_RS21300 bca34cf65f6c290b340309032d670b02 277 Gene3D G3DSA:3.40.50.720 112 276 8.8E-31 T 29-03-2018 CSW12_RS11110 c8b3eb1c7a13e99e0574a254b9203763 137 Pfam PF03899 ATP synthase I chain 9 102 2.1E-12 T 29-03-2018 IPR005598 ATP synthase protein I CSW12_RS11110 c8b3eb1c7a13e99e0574a254b9203763 137 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 124 6.0E-46 T 29-03-2018 CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 Gene3D G3DSA:3.40.50.300 219 354 3.7E-45 T 29-03-2018 CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 SUPERFAMILY SSF52540 71 358 3.32E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 SMART SM00487 23 220 2.5E-56 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 Gene3D G3DSA:3.40.50.300 3 218 5.9E-55 T 29-03-2018 CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 Pfam PF03880 DbpA RNA binding domain 407 477 3.7E-20 T 29-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 Pfam PF00270 DEAD/DEAH box helicase 28 194 8.9E-48 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 SMART SM00490 256 337 1.8E-35 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 6 480 76.443 T 29-03-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 CSW12_RS27115 0bc5e0fe2d29019599f25f2c85d00aba 481 Pfam PF00271 Helicase conserved C-terminal domain 230 337 1.1E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 Pfam PF00815 Histidinol dehydrogenase 26 425 4.1E-177 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 168 194 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 198 223 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 359 377 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PRINTS PR00083 Histidinol dehydrogenase signature 318 343 1.6E-89 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 424 1.1E-170 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 425 43.63 T 29-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 PIRSF PIRSF000099 2 428 1.9E-183 T 29-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 Gene3D G3DSA:3.40.50.1980 26 223 2.0E-88 T 29-03-2018 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 Gene3D G3DSA:3.40.50.1980 224 369 4.4E-68 T 29-03-2018 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 SUPERFAMILY SSF53720 27 425 9.81E-84 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS06610 937957d2df04b0ffa88a1e98c28ab123 429 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 29-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CSW12_RS23705 9d59defc0ed22597f034bbe83860d514 187 Gene3D G3DSA:3.40.1050.10 1 182 3.3E-35 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS23705 9d59defc0ed22597f034bbe83860d514 187 SUPERFAMILY SSF53056 1 181 1.96E-43 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS23705 9d59defc0ed22597f034bbe83860d514 187 SMART SM00947 26 182 1.0E-40 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS23705 9d59defc0ed22597f034bbe83860d514 187 Pfam PF00484 Carbonic anhydrase 33 178 2.3E-20 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS25950 74caccea9d37a8e83a3f9bf3c16eaf11 505 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 9 499 7.0E-191 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CSW12_RS25950 74caccea9d37a8e83a3f9bf3c16eaf11 505 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 499 9.6E-161 T 29-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CSW12_RS25950 74caccea9d37a8e83a3f9bf3c16eaf11 505 ProSitePatterns PS01303 BCCT family of transporters signature. 315 324 - T 29-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CSW12_RS18990 ef199c468d14db4b66c2e3b89a372f76 294 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 30 287 1.9E-67 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 CSW12_RS18990 ef199c468d14db4b66c2e3b89a372f76 294 Pfam PF09323 Domain of unknown function (DUF1980) 12 199 1.2E-46 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 CSW12_RS17240 d274d16eeb99c07c53b0d7dd1704e4b0 389 Gene3D G3DSA:1.20.1250.20 5 197 2.1E-21 T 29-03-2018 CSW12_RS17240 d274d16eeb99c07c53b0d7dd1704e4b0 389 SUPERFAMILY SSF103473 9 379 8.11E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS17240 d274d16eeb99c07c53b0d7dd1704e4b0 389 Pfam PF07690 Major Facilitator Superfamily 16 340 2.3E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS17240 d274d16eeb99c07c53b0d7dd1704e4b0 389 Gene3D G3DSA:1.20.1250.20 198 382 9.9E-30 T 29-03-2018 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 14 234 1.6E-48 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 149 164 1.4E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 165 187 1.4E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 218 233 1.4E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 PRINTS PR00123 ATP synthase A subunit signature 77 93 1.4E-18 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 Hamap MF_01393 ATP synthase subunit a [atpB]. 7 238 13.84 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 ProSitePatterns PS00449 ATP synthase a subunit signature. 168 177 - T 29-03-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 Gene3D G3DSA:1.20.120.220 68 239 3.9E-46 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 SUPERFAMILY SSF81336 69 231 8.5E-42 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26335 951194ed8efecf005b120b636888d0d1 239 Pfam PF00119 ATP synthase A chain 20 231 4.8E-58 T 29-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS20325 00390ec8962e62efe582dfb85d7ea6f7 240 PIRSF PIRSF039085 1 240 1.7E-115 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CSW12_RS20325 00390ec8962e62efe582dfb85d7ea6f7 240 Pfam PF00005 ABC transporter 17 165 2.3E-39 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS20325 00390ec8962e62efe582dfb85d7ea6f7 240 Gene3D G3DSA:3.40.50.300 1 239 1.0E-77 T 29-03-2018 CSW12_RS20325 00390ec8962e62efe582dfb85d7ea6f7 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS20325 00390ec8962e62efe582dfb85d7ea6f7 240 SMART SM00382 26 213 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS20325 00390ec8962e62efe582dfb85d7ea6f7 240 SUPERFAMILY SSF52540 1 235 8.05E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 Pfam PF00742 Homoserine dehydrogenase 138 316 9.5E-65 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 SUPERFAMILY SSF55021 349 414 3.88E-8 T 29-03-2018 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 Gene3D G3DSA:3.30.360.10 159 299 7.8E-54 T 29-03-2018 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 SUPERFAMILY SSF55347 138 303 3.27E-53 T 29-03-2018 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 SUPERFAMILY SSF51735 1 159 2.03E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 PIRSF PIRSF000098 2 427 3.8E-174 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 2.0E-21 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 Gene3D G3DSA:3.40.50.720 1 158 1.8E-31 T 29-03-2018 CSW12_RS18020 aca6bfdbda8a08fd99b37f647ec57093 431 Gene3D G3DSA:3.30.70.260 341 430 3.9E-9 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 483 3.3E-45 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Gene3D G3DSA:3.40.30.10 2 93 9.4E-25 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Pfam PF13192 Thioredoxin domain 125 193 2.4E-7 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Gene3D G3DSA:3.50.50.60 437 508 8.0E-12 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 508 3.2E-242 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 SUPERFAMILY SSF52833 2 100 1.83E-30 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 SUPERFAMILY SSF52833 104 194 3.68E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 SUPERFAMILY SSF51905 194 504 3.95E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Gene3D G3DSA:3.50.50.60 331 436 1.1E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 1.2E-39 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 1.2E-39 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 1.2E-39 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 458 480 1.2E-39 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 1.2E-39 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Gene3D G3DSA:3.40.30.10 102 195 2.6E-6 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 Gene3D G3DSA:3.40.50.720 204 330 8.6E-21 T 29-03-2018 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 468 486 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 5.9E-65 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 PIRSF PIRSF000238 2 508 3.5E-258 T 29-03-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 CSW12_RS00550 b3cb7489279180c582e1790d7fa31c63 508 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CSW12_RS15685 0ee29daa2ecee94d20d7871940f5b917 236 Gene3D G3DSA:3.40.50.150 17 231 9.7E-30 T 29-03-2018 CSW12_RS15685 0ee29daa2ecee94d20d7871940f5b917 236 SUPERFAMILY SSF53335 25 212 5.06E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS15685 0ee29daa2ecee94d20d7871940f5b917 236 Pfam PF13649 Methyltransferase domain 63 156 5.1E-18 T 29-03-2018 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 Gene3D G3DSA:1.10.4030.10 22 122 6.9E-10 T 29-03-2018 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 Pfam PF13616 PPIC-type PPIASE domain 132 224 3.9E-28 T 29-03-2018 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 Hamap MF_01145 Foldase protein PrsA [prsA]. 1 280 22.824 T 29-03-2018 IPR023059 Foldase protein PrsA GO:0003755 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 162 183 - T 29-03-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 Gene3D G3DSA:3.10.50.40 124 247 4.6E-38 T 29-03-2018 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 SUPERFAMILY SSF54534 122 223 3.79E-34 T 29-03-2018 CSW12_RS04505 b68ed9e6728cb74662f399ccef51fb86 289 SUPERFAMILY SSF109998 34 163 1.96E-19 T 29-03-2018 IPR027304 Trigger factor/SurA domain CSW12_RS10825 097f7cff417fcf446368c280344d7d23 86 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 17 83 1.8E-9 T 29-03-2018 IPR008792 Coenzyme PQQ synthesis D CSW12_RS20400 792c6cdc63eade3b3bf975c1225d549f 299 Pfam PF01515 Phosphate acetyl/butaryl transferase 77 294 1.0E-50 T 29-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CSW12_RS20400 792c6cdc63eade3b3bf975c1225d549f 299 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 296 5.0E-130 T 29-03-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 CSW12_RS20400 792c6cdc63eade3b3bf975c1225d549f 299 PIRSF PIRSF000428 1 299 1.8E-83 T 29-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CSW12_RS20400 792c6cdc63eade3b3bf975c1225d549f 299 SUPERFAMILY SSF53659 4 297 4.8E-62 T 29-03-2018 CSW12_RS20400 792c6cdc63eade3b3bf975c1225d549f 299 Gene3D G3DSA:3.40.50.10750 114 270 2.9E-41 T 29-03-2018 CSW12_RS12550 b32463c8edfb65e7951a544044f7e3ba 310 Gene3D G3DSA:1.10.8.300 204 302 1.7E-29 T 29-03-2018 CSW12_RS12550 b32463c8edfb65e7951a544044f7e3ba 310 Gene3D G3DSA:3.40.50.300 1 203 1.0E-28 T 29-03-2018 CSW12_RS12550 b32463c8edfb65e7951a544044f7e3ba 310 PIRSF PIRSF002849 1 307 3.6E-127 T 29-03-2018 CSW12_RS12550 b32463c8edfb65e7951a544044f7e3ba 310 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 34 164 1.4E-60 T 29-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CSW12_RS12550 b32463c8edfb65e7951a544044f7e3ba 310 SUPERFAMILY SSF52540 3 290 3.15E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.384 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 Gene3D G3DSA:2.40.50.140 1 114 1.1E-50 T 29-03-2018 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 PIRSF PIRSF002158 3 276 1.7E-99 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 8.0E-58 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 SUPERFAMILY SSF50104 126 273 9.03E-62 T 29-03-2018 IPR008991 Translation protein SH3-like domain CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 SMART SM01382 124 253 9.4E-94 T 29-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 4.2E-34 T 29-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 Gene3D G3DSA:2.30.30.30 119 195 1.5E-33 T 29-03-2018 IPR014722 Ribosomal protein L2 domain 2 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 Gene3D G3DSA:4.10.950.10 197 275 6.6E-37 T 29-03-2018 IPR014726 Ribosomal protein L2, domain 3 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 29-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 SUPERFAMILY SSF50249 3 125 1.3E-50 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 3.0E-141 T 29-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CSW12_RS28000 032cab93f3c4297ac311de857fb197d4 276 SMART SM01383 42 118 2.2E-47 T 29-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS25930 a6aad2f2c166774bf633ab95f3188039 403 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 196 401 1.8E-71 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS25930 a6aad2f2c166774bf633ab95f3188039 403 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 401 2.5E-138 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 CSW12_RS25930 a6aad2f2c166774bf633ab95f3188039 403 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 9 81 4.2E-22 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS12270 39b193033e3d5c40566614fc9d5e9bfe 156 SUPERFAMILY SSF109854 9 156 9.34E-31 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS12270 39b193033e3d5c40566614fc9d5e9bfe 156 Gene3D G3DSA:1.20.120.450 2 149 2.5E-15 T 29-03-2018 CSW12_RS12270 39b193033e3d5c40566614fc9d5e9bfe 156 Pfam PF12867 DinB superfamily 11 139 6.2E-12 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS11315 8ee727f084e25294f69bc5ea8f5f6729 126 SUPERFAMILY SSF46785 15 120 8.13E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11315 8ee727f084e25294f69bc5ea8f5f6729 126 Gene3D G3DSA:1.10.10.10 25 126 2.6E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11315 8ee727f084e25294f69bc5ea8f5f6729 126 Pfam PF01638 HxlR-like helix-turn-helix 27 115 5.4E-39 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS14805 d9bd63ad1c8cabdd6b9ba294a43465ab 308 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 2.7E-5 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS14805 d9bd63ad1c8cabdd6b9ba294a43465ab 308 Gene3D G3DSA:3.40.50.720 139 252 1.3E-9 T 29-03-2018 CSW12_RS14805 d9bd63ad1c8cabdd6b9ba294a43465ab 308 SUPERFAMILY SSF51735 116 254 8.99E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS14805 d9bd63ad1c8cabdd6b9ba294a43465ab 308 Gene3D G3DSA:3.90.180.10 2 138 1.2E-22 T 29-03-2018 CSW12_RS14805 d9bd63ad1c8cabdd6b9ba294a43465ab 308 SUPERFAMILY SSF50129 6 146 7.23E-25 T 29-03-2018 IPR011032 GroES-like CSW12_RS29345 9f4f7647da4376aae6b5b37a58a1e1b4 390 SUPERFAMILY SSF52540 107 311 1.4E-21 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS29345 9f4f7647da4376aae6b5b37a58a1e1b4 390 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 146 159 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS29345 9f4f7647da4376aae6b5b37a58a1e1b4 390 Gene3D G3DSA:3.40.50.300 3 356 5.4E-20 T 29-03-2018 CSW12_RS29345 9f4f7647da4376aae6b5b37a58a1e1b4 390 Pfam PF01580 FtsK/SpoIIIE family 118 289 3.5E-24 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS03130 72fb13f23d1e0463e3d6e96fd2b66a27 186 SUPERFAMILY SSF55469 8 182 1.24E-35 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS03130 72fb13f23d1e0463e3d6e96fd2b66a27 186 Gene3D G3DSA:3.40.109.10 1 186 1.8E-32 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS03130 72fb13f23d1e0463e3d6e96fd2b66a27 186 Pfam PF00881 Nitroreductase family 11 164 7.1E-28 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS15720 9fae5d478b25a5257e825b1aa79be918 333 SUPERFAMILY SSF53686 9 319 7.46E-98 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS15720 9fae5d478b25a5257e825b1aa79be918 333 Gene3D G3DSA:3.40.50.1100 35 141 3.0E-32 T 29-03-2018 CSW12_RS15720 9fae5d478b25a5257e825b1aa79be918 333 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CSW12_RS15720 9fae5d478b25a5257e825b1aa79be918 333 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 27 325 4.6E-122 T 29-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CSW12_RS15720 9fae5d478b25a5257e825b1aa79be918 333 Gene3D G3DSA:3.40.50.1100 142 319 1.2E-42 T 29-03-2018 CSW12_RS15720 9fae5d478b25a5257e825b1aa79be918 333 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 311 3.9E-80 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS26000 b64fb495a2f5339ccc887f2fd7b2b7be 74 Pfam PF07872 Protein of unknown function (DUF1659) 8 51 3.1E-16 T 29-03-2018 IPR012454 Protein of unknown function DUF1659 CSW12_RS14835 5679b2779092a00bca84d644255db8fc 197 Pfam PF13222 Protein of unknown function (DUF4030) 54 195 3.6E-71 T 29-03-2018 IPR025108 Protein of unknown function DUF4030 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 217 5.1E-48 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 Gene3D G3DSA:3.30.2350.10 63 228 1.4E-34 T 29-03-2018 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 Pfam PF00849 RNA pseudouridylate synthase 62 186 1.1E-16 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 97 111 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 SMART SM00363 1 57 3.4E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 SUPERFAMILY SSF55174 1 54 9.25E-12 T 29-03-2018 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 Pfam PF01479 S4 domain 1 46 6.8E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 Gene3D G3DSA:3.10.290.10 1 62 5.1E-15 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS22360 0e4fe6330794b5eac3480b415986d0db 229 SUPERFAMILY SSF55120 61 222 8.64E-41 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS24615 59db1db68c4c6500bf30f92f2971be01 323 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 311 3.3E-142 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CSW12_RS24615 59db1db68c4c6500bf30f92f2971be01 323 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 2 322 1.1E-128 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CSW12_RS24615 59db1db68c4c6500bf30f92f2971be01 323 SUPERFAMILY SSF56655 2 314 6.41E-106 T 29-03-2018 CSW12_RS24615 59db1db68c4c6500bf30f92f2971be01 323 Gene3D G3DSA:3.30.540.10 1 157 9.0E-60 T 29-03-2018 CSW12_RS24615 59db1db68c4c6500bf30f92f2971be01 323 Gene3D G3DSA:3.30.540.10 158 322 1.6E-53 T 29-03-2018 CSW12_RS24615 59db1db68c4c6500bf30f92f2971be01 323 PIRSF PIRSF004532 1 322 2.8E-150 T 29-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CSW12_RS12970 8158b9099b52d48fad774aeeb3628255 215 Gene3D G3DSA:3.40.50.880 1 214 4.9E-43 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS12970 8158b9099b52d48fad774aeeb3628255 215 SUPERFAMILY SSF52317 1 185 4.07E-42 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS12970 8158b9099b52d48fad774aeeb3628255 215 Pfam PF01965 DJ-1/PfpI family 2 165 1.0E-22 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 Gene3D G3DSA:3.40.1160.10 1 234 4.3E-71 T 29-03-2018 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 Pfam PF13840 ACT domain 334 396 1.7E-11 T 29-03-2018 IPR027795 GATS-like ACT domain CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 Gene3D G3DSA:3.30.70.260 235 324 1.8E-18 T 29-03-2018 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 PIRSF PIRSF000726 1 61 5.5E-19 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 PIRSF PIRSF000726 53 405 1.8E-128 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 399 3.2E-143 T 29-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 SUPERFAMILY SSF55021 250 322 4.89E-13 T 29-03-2018 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 61 399 3.5E-118 T 29-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 29-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 Pfam PF01842 ACT domain 272 321 8.1E-7 T 29-03-2018 IPR002912 ACT domain CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 SUPERFAMILY SSF53633 3 243 2.23E-72 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 Pfam PF00696 Amino acid kinase family 3 224 4.9E-51 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 Gene3D G3DSA:3.30.70.260 325 401 1.6E-18 T 29-03-2018 CSW12_RS18765 820918c6d55fe9da45ed3e49cabc9677 409 SUPERFAMILY SSF55021 326 400 3.97E-20 T 29-03-2018 CSW12_RS21750 259ee71cd99f688108efee9c15ea4efb 314 Pfam PF01497 Periplasmic binding protein 61 284 7.4E-31 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS21750 259ee71cd99f688108efee9c15ea4efb 314 Gene3D G3DSA:3.40.50.1980 150 314 9.9E-33 T 29-03-2018 CSW12_RS21750 259ee71cd99f688108efee9c15ea4efb 314 SUPERFAMILY SSF53807 38 307 9.42E-60 T 29-03-2018 CSW12_RS21750 259ee71cd99f688108efee9c15ea4efb 314 Gene3D G3DSA:3.40.50.1980 23 149 9.7E-27 T 29-03-2018 CSW12_RS23140 9ca4eb69e28b71650d9806959c1bc444 204 SUPERFAMILY SSF50249 95 203 2.94E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS23140 9ca4eb69e28b71650d9806959c1bc444 204 Gene3D G3DSA:2.40.50.140 94 203 2.1E-40 T 29-03-2018 CSW12_RS23140 9ca4eb69e28b71650d9806959c1bc444 204 Pfam PF01588 Putative tRNA binding domain 99 200 1.6E-27 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CSW12_RS23140 9ca4eb69e28b71650d9806959c1bc444 204 Pfam PF14794 Domain of unknown function (DUF4479) 27 94 1.2E-24 T 29-03-2018 IPR027855 Domain of unknown function DUF4479 CSW12_RS23140 9ca4eb69e28b71650d9806959c1bc444 204 Gene3D G3DSA:3.30.1940.10 27 93 4.4E-25 T 29-03-2018 IPR027855 Domain of unknown function DUF4479 CSW12_RS06395 029e20e159196cd5892b03c1a732d532 391 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 388 7.5E-131 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CSW12_RS06395 029e20e159196cd5892b03c1a732d532 391 SUPERFAMILY SSF52266 270 389 8.79E-12 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS06395 029e20e159196cd5892b03c1a732d532 391 Gene3D G3DSA:3.40.50.1110 89 391 1.5E-6 T 29-03-2018 CSW12_RS06395 029e20e159196cd5892b03c1a732d532 391 PIRSF PIRSF021438 1 391 1.0E-142 T 29-03-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes CSW12_RS06395 029e20e159196cd5892b03c1a732d532 391 Pfam PF04914 DltD protein 40 389 5.5E-123 T 29-03-2018 IPR006998 DltD CSW12_RS17135 aa936f7bdfcab536cc361386c51e09e1 243 PIRSF PIRSF009160 1 243 5.2E-92 T 29-03-2018 IPR010539 Protein of unknown function UCP009160 CSW12_RS17135 aa936f7bdfcab536cc361386c51e09e1 243 Pfam PF12811 Bax inhibitor 1 like 5 240 3.4E-71 T 29-03-2018 IPR010539 Protein of unknown function UCP009160 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 179 310 2.0E-64 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 Pfam PF01641 SelR domain 183 301 3.8E-48 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 7 166 35.874 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 SUPERFAMILY SSF55068 3 171 6.02E-71 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 SUPERFAMILY SSF51316 178 317 7.85E-60 T 29-03-2018 IPR011057 Mss4-like CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 8 159 1.8E-59 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 Gene3D G3DSA:3.30.1060.10 1 172 1.1E-64 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 Gene3D G3DSA:2.170.150.20 173 317 2.4E-56 T 29-03-2018 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 172 302 37.917 T 29-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS26960 4cece655b465437877d7e2582a78db2a 321 Pfam PF01625 Peptide methionine sulfoxide reductase 10 159 2.2E-59 T 29-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 SMART SM01027 252 363 1.6E-5 T 29-03-2018 IPR022712 Beta-Casp domain CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 372 425 2.5E-6 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 Pfam PF10996 Beta-Casp domain 227 362 8.7E-7 T 29-03-2018 IPR022712 Beta-Casp domain CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 Pfam PF00753 Metallo-beta-lactamase superfamily 27 197 6.3E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 SUPERFAMILY SSF56281 18 422 7.19E-70 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 SMART SM00849 30 239 3.2E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS19120 75bfa443cdbcb67946b2ac14aa8c0db2 436 Gene3D G3DSA:3.60.15.10 8 271 2.5E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 SUPERFAMILY SSF52540 5 254 9.58E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 Pfam PF00005 ABC transporter 26 183 4.7E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 1.9E-28 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 SMART SM00382 34 233 2.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 Gene3D G3DSA:3.40.50.300 2 326 4.1E-80 T 29-03-2018 CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS28595 ca9560e0fd055cd31d84db6730e9e498 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 8.8E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS21470 ee845b93034ad6a98cfabe876b6bc098 345 Gene3D G3DSA:1.10.3470.10 17 344 6.0E-71 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS21470 ee845b93034ad6a98cfabe876b6bc098 345 Pfam PF01032 FecCD transport family 31 337 2.6E-97 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS21470 ee845b93034ad6a98cfabe876b6bc098 345 SUPERFAMILY SSF81345 15 337 4.58E-84 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS18175 17701c2603496209ad12e94373072251 139 SUPERFAMILY SSF55331 2 132 1.62E-34 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CSW12_RS18175 17701c2603496209ad12e94373072251 139 Pfam PF14552 Tautomerase enzyme 39 123 1.3E-21 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CSW12_RS18175 17701c2603496209ad12e94373072251 139 Gene3D G3DSA:3.30.429.10 2 139 9.1E-26 T 29-03-2018 CSW12_RS26855 87c7de6ee90c02599a1ea22e9eec3e58 351 Pfam PF07694 5TMR of 5TMR-LYT 32 167 1.3E-11 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CSW12_RS26855 87c7de6ee90c02599a1ea22e9eec3e58 351 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 188 348 3.0E-43 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26855 87c7de6ee90c02599a1ea22e9eec3e58 351 SMART SM00267 180 350 1.7E-43 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26855 87c7de6ee90c02599a1ea22e9eec3e58 351 Pfam PF00990 Diguanylate cyclase, GGDEF domain 191 346 9.7E-36 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26855 87c7de6ee90c02599a1ea22e9eec3e58 351 Gene3D G3DSA:3.30.70.270 185 351 9.3E-45 T 29-03-2018 CSW12_RS26855 87c7de6ee90c02599a1ea22e9eec3e58 351 SUPERFAMILY SSF55073 196 348 3.06E-39 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 SUPERFAMILY SSF52540 309 754 5.2E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Gene3D G3DSA:3.40.50.300 271 752 4.2E-40 T 29-03-2018 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 1 1171 0.0 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1170 67.208 T 29-03-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Gene3D G3DSA:3.40.50.300 1 127 4.1E-32 T 29-03-2018 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Gene3D G3DSA:3.40.50.300 128 270 8.2E-33 T 29-03-2018 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Gene3D G3DSA:3.90.320.10 753 1020 3.4E-10 T 29-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Pfam PF13361 UvrD-like helicase C-terminal domain 300 670 3.5E-9 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CSW12_RS04965 556a071b0545c40ae49fc333d13cb382 1171 Pfam PF12705 PD-(D/E)XK nuclease superfamily 795 1139 5.4E-54 T 29-03-2018 CSW12_RS13770 17e9d4f498b1710292cc93df34bad492 154 Gene3D G3DSA:3.90.79.10 5 150 4.1E-18 T 29-03-2018 CSW12_RS13770 17e9d4f498b1710292cc93df34bad492 154 SUPERFAMILY SSF55811 10 134 1.27E-21 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS13770 17e9d4f498b1710292cc93df34bad492 154 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS13770 17e9d4f498b1710292cc93df34bad492 154 Pfam PF00293 NUDIX domain 19 130 8.4E-11 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS08770 c914f977d38b5631b7f8a5444a142954 199 Gene3D G3DSA:3.40.50.1950 6 191 4.7E-30 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CSW12_RS08770 c914f977d38b5631b7f8a5444a142954 199 SUPERFAMILY SSF52507 3 180 2.09E-31 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CSW12_RS08770 c914f977d38b5631b7f8a5444a142954 199 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 4.3E-106 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CSW12_RS08770 c914f977d38b5631b7f8a5444a142954 199 Pfam PF02441 Flavoprotein 6 159 1.4E-18 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CSW12_RS08770 c914f977d38b5631b7f8a5444a142954 199 PIRSF PIRSF001390 1 195 2.2E-81 T 29-03-2018 IPR014214 Dipicolinic acid synthetase, subunit B CSW12_RS26550 0447bfa7c4b0749fb1348d16ce880a5b 583 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 246 404 1.5E-31 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CSW12_RS26550 0447bfa7c4b0749fb1348d16ce880a5b 583 SUPERFAMILY SSF55486 241 569 5.94E-55 T 29-03-2018 CSW12_RS26550 0447bfa7c4b0749fb1348d16ce880a5b 583 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 132 9.1E-11 T 29-03-2018 IPR011096 FTP domain CSW12_RS26550 0447bfa7c4b0749fb1348d16ce880a5b 583 Gene3D G3DSA:1.10.390.10 416 575 2.7E-29 T 29-03-2018 CSW12_RS26550 0447bfa7c4b0749fb1348d16ce880a5b 583 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 418 569 3.3E-26 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CSW12_RS26550 0447bfa7c4b0749fb1348d16ce880a5b 583 Gene3D G3DSA:3.10.170.10 245 408 5.8E-34 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF55008 74 145 1.96E-21 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF55008 4 71 5.63E-20 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 229 799 2.5E-204 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 711 4.5E-49 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Gene3D G3DSA:3.40.50.1000 623 763 3.2E-43 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 32 55 3.3E-15 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 212 237 3.3E-15 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 3.3E-15 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Gene3D G3DSA:3.40.1110.10 513 622 9.5E-36 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF81653 300 396 9.02E-31 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 8 70 3.8E-9 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 138 1.5E-14 T 29-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Gene3D G3DSA:3.30.70.100 73 150 7.7E-24 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Gene3D G3DSA:3.30.70.100 3 72 4.0E-21 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 500 506 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 214 233 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 674 691 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 286 304 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 419 433 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 118 138 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 481 496 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00943 Copper-transporting ATPase signature 266 285 8.6E-17 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 269 784 3.2E-95 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 697 716 3.0E-28 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 654 3.0E-28 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 346 360 3.0E-28 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 633 3.0E-28 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 512 3.0E-28 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 732 3.0E-28 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF81665 397 489 2.35E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF81665 260 300 2.35E-11 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 800 2.9E-187 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Gene3D G3DSA:1.20.1110.10 261 512 7.2E-48 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Pfam PF00403 Heavy-metal-associated domain 77 137 7.6E-17 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Pfam PF00403 Heavy-metal-associated domain 9 68 3.5E-16 T 29-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 79 108 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF56784 496 516 3.57E-63 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 SUPERFAMILY SSF56784 555 797 3.57E-63 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 Pfam PF00122 E1-E2 ATPase 297 476 2.2E-59 T 29-03-2018 CSW12_RS09140 d40112a128b273d8a91d6e6b9edf3261 806 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 29-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CSW12_RS25180 813cfadb8a37fe6f4f3f1f425556277a 352 Gene3D G3DSA:3.60.10.10 40 350 2.0E-26 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS25180 813cfadb8a37fe6f4f3f1f425556277a 352 SUPERFAMILY SSF56219 42 352 2.75E-30 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS17500 ea57defbe431a07e7028ae75272f7ded 153 SUPERFAMILY SSF109854 1 140 7.33E-30 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS17500 ea57defbe431a07e7028ae75272f7ded 153 Gene3D G3DSA:1.20.120.450 1 145 3.1E-18 T 29-03-2018 CSW12_RS10550 c49ca88a344af364086ce42b860260e0 151 SUPERFAMILY SSF109854 7 148 1.79E-24 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS10550 c49ca88a344af364086ce42b860260e0 151 Gene3D G3DSA:1.20.120.450 6 146 1.5E-20 T 29-03-2018 CSW12_RS10550 c49ca88a344af364086ce42b860260e0 151 Pfam PF12867 DinB superfamily 9 141 2.4E-20 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS12545 3a9f663f18cb8a71aae89bc8bcf14654 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 75 3.3E-19 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CSW12_RS12545 3a9f663f18cb8a71aae89bc8bcf14654 97 SUPERFAMILY SSF54909 1 92 2.22E-26 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS12545 3a9f663f18cb8a71aae89bc8bcf14654 97 Gene3D G3DSA:3.30.70.100 1 95 1.2E-22 T 29-03-2018 CSW12_RS08510 633bda24528116edc32942f2b24c7126 330 PIRSF PIRSF002465 1 330 5.2E-131 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CSW12_RS08510 633bda24528116edc32942f2b24c7126 330 SUPERFAMILY SSF53659 1 326 3.5E-107 T 29-03-2018 CSW12_RS08510 633bda24528116edc32942f2b24c7126 330 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 326 5.6E-136 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CSW12_RS08510 633bda24528116edc32942f2b24c7126 330 Gene3D G3DSA:3.40.718.10 1 329 1.3E-108 T 29-03-2018 CSW12_RS08510 633bda24528116edc32942f2b24c7126 330 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 330 154.615 T 29-03-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CSW12_RS08510 633bda24528116edc32942f2b24c7126 330 Pfam PF02504 Fatty acid synthesis protein 1 317 2.3E-128 T 29-03-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 1.9E-32 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 SUPERFAMILY SSF46785 2 74 2.99E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 73 4.0E-31 T 29-03-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 Gene3D G3DSA:3.40.50.2020 74 271 9.1E-33 T 29-03-2018 CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 Gene3D G3DSA:1.10.10.10 1 73 1.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 SUPERFAMILY SSF53271 89 267 1.56E-41 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 Pfam PF00156 Phosphoribosyl transferase domain 107 264 4.7E-24 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS27575 c89e1b5b77afd297a7ed60cb74b95d81 282 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 4 269 1.4E-120 T 29-03-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 CSW12_RS08300 92aa2fda15d4070aca9f6b557c8aabc6 180 Pfam PF00156 Phosphoribosyl transferase domain 8 163 1.1E-20 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS08300 92aa2fda15d4070aca9f6b557c8aabc6 180 SUPERFAMILY SSF53271 6 174 3.8E-44 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS08300 92aa2fda15d4070aca9f6b557c8aabc6 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 39.353 T 29-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CSW12_RS08300 92aa2fda15d4070aca9f6b557c8aabc6 180 Gene3D G3DSA:3.40.50.2020 1 180 8.6E-44 T 29-03-2018 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 SMART SM00382 174 317 4.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Pfam PF08448 PAS fold 18 118 7.0E-7 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 SUPERFAMILY SSF55785 9 114 9.77E-13 T 29-03-2018 IPR000014 PAS domain CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:3.40.50.300 162 325 4.7E-26 T 29-03-2018 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:1.10.10.60 416 461 1.1E-17 T 29-03-2018 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Pfam PF00158 Sigma-54 interaction domain 154 319 1.7E-62 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 SUPERFAMILY SSF52540 154 396 2.17E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 178 191 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Pfam PF02954 Bacterial regulatory protein, Fis family 416 456 5.0E-14 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:3.30.450.20 5 161 1.7E-9 T 29-03-2018 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 439 3.0E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 439 459 3.0E-10 T 29-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 29-03-2018 IPR025944 Sigma-54 interaction domain, conserved site CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 SUPERFAMILY SSF46689 366 457 7.53E-19 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 125 8.9E-7 T 29-03-2018 IPR000014 PAS domain CSW12_RS16485 d42ecece32ca9cb22e750bb45354cde1 461 Gene3D G3DSA:1.10.8.60 326 415 5.3E-25 T 29-03-2018 CSW12_RS23480 203a33190559ff9203285d36f4f4bd5c 277 Pfam PF12146 Serine aminopeptidase, S33 18 252 5.3E-58 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS23480 203a33190559ff9203285d36f4f4bd5c 277 Gene3D G3DSA:3.40.50.1820 5 276 2.7E-34 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS23480 203a33190559ff9203285d36f4f4bd5c 277 SUPERFAMILY SSF53474 13 264 2.41E-33 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS13690 b16948c8f178cc1955b452b7d4eeb4b6 226 SUPERFAMILY SSF56436 13 85 1.06E-54 T 29-03-2018 IPR016187 C-type lectin fold CSW12_RS13690 b16948c8f178cc1955b452b7d4eeb4b6 226 SUPERFAMILY SSF56436 112 225 1.06E-54 T 29-03-2018 IPR016187 C-type lectin fold CSW12_RS13690 b16948c8f178cc1955b452b7d4eeb4b6 226 Gene3D G3DSA:3.90.1580.10 61 226 2.5E-46 T 29-03-2018 CSW12_RS13690 b16948c8f178cc1955b452b7d4eeb4b6 226 Gene3D G3DSA:3.90.1580.10 7 60 0.077 T 29-03-2018 CSW12_RS13690 b16948c8f178cc1955b452b7d4eeb4b6 226 Pfam PF03781 Sulfatase-modifying factor enzyme 1 13 224 1.9E-39 T 29-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CSW12_RS03155 c73534275a0d252abc1f8633862dc9de 411 Gene3D G3DSA:3.40.50.1820 5 369 2.7E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS03155 c73534275a0d252abc1f8633862dc9de 411 Pfam PF07819 PGAP1-like protein 14 153 2.8E-10 T 29-03-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 CSW12_RS03155 c73534275a0d252abc1f8633862dc9de 411 SUPERFAMILY SSF53474 8 213 6.46E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS01995 ab1d82d4472c4e4772a2b75acbda4f7d 321 Gene3D G3DSA:1.10.3720.10 2 308 9.4E-37 T 29-03-2018 CSW12_RS01995 ab1d82d4472c4e4772a2b75acbda4f7d 321 SUPERFAMILY SSF161098 92 302 3.01E-14 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01995 ab1d82d4472c4e4772a2b75acbda4f7d 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 319 4.5E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS09850 6a6e209a3398c9de479df86605586364 698 Gene3D G3DSA:3.40.50.410 25 279 7.8E-12 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS09850 6a6e209a3398c9de479df86605586364 698 SUPERFAMILY SSF53300 33 178 2.47E-8 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS15485 efed96de18fc3c9173fa7693c789c239 314 Gene3D G3DSA:3.40.50.2300 1 152 6.7E-23 T 29-03-2018 CSW12_RS15485 efed96de18fc3c9173fa7693c789c239 314 Pfam PF08664 YcbB domain 166 302 1.3E-49 T 29-03-2018 IPR013972 YcbB domain CSW12_RS15485 efed96de18fc3c9173fa7693c789c239 314 SMART SM00448 1 114 3.7E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS15485 efed96de18fc3c9173fa7693c789c239 314 Pfam PF00072 Response regulator receiver domain 4 114 1.1E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS15485 efed96de18fc3c9173fa7693c789c239 314 SUPERFAMILY SSF52172 5 135 1.71E-23 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 SUPERFAMILY SSF46894 140 194 9.18E-10 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 SMART SM00448 4 120 9.0E-13 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 9.3E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 9.3E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 9.3E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 Gene3D G3DSA:3.40.50.2300 1 127 7.6E-18 T 29-03-2018 CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 Gene3D G3DSA:1.10.10.10 128 195 1.5E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 SUPERFAMILY SSF52172 1 125 9.53E-18 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS30825 dd525f192230fb0b36824cd99d01477d 197 Pfam PF00072 Response regulator receiver domain 7 114 5.1E-14 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS02725 9822a91eba98250dd825613b80947d85 236 PIRSF PIRSF032442 21 236 3.7E-75 T 29-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CSW12_RS02725 9822a91eba98250dd825613b80947d85 236 Gene3D G3DSA:3.90.70.10 57 236 5.2E-23 T 29-03-2018 CSW12_RS02725 9822a91eba98250dd825613b80947d85 236 Pfam PF13529 Peptidase_C39 like family 48 207 3.8E-41 T 29-03-2018 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 Pfam PF07687 Peptidase dimerisation domain 182 274 8.9E-16 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 368 7.4E-168 T 29-03-2018 IPR010162 Peptidase M20B, peptidase T-like CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 PIRSF PIRSF001123 261 372 2.6E-5 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 PIRSF PIRSF001123 4 96 0.033 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 PIRSF PIRSF001123 80 210 1.3E-4 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 SUPERFAMILY SSF55031 180 285 2.75E-20 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 Gene3D G3DSA:3.40.630.10 1 372 5.2E-62 T 29-03-2018 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 Pfam PF01546 Peptidase family M20/M25/M40 74 368 3.0E-24 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 SUPERFAMILY SSF53187 288 371 2.02E-64 T 29-03-2018 CSW12_RS20295 63d8551ac897d89577eec72cefae6565 372 SUPERFAMILY SSF53187 5 178 2.02E-64 T 29-03-2018 CSW12_RS27850 45674d19f50215a3e0afe2070ab14b54 367 Gene3D G3DSA:3.40.50.1010 162 298 7.4E-27 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS27850 45674d19f50215a3e0afe2070ab14b54 367 SUPERFAMILY SSF88723 167 295 1.71E-25 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS27850 45674d19f50215a3e0afe2070ab14b54 367 SMART SM00670 167 274 1.0E-13 T 29-03-2018 IPR002716 PIN domain CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 Gene3D G3DSA:3.30.230.30 4 133 1.4E-47 T 29-03-2018 IPR001498 Impact, N-terminal CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 Gene3D G3DSA:3.30.70.240 135 198 5.6E-17 T 29-03-2018 CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 201 8.1E-80 T 29-03-2018 IPR015796 Impact family, bacterial/archaeal CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 29-03-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 SUPERFAMILY SSF54211 3 131 5.31E-45 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.5E-18 T 29-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 Pfam PF01205 Uncharacterized protein family UPF0029 19 122 1.6E-33 T 29-03-2018 IPR001498 Impact, N-terminal CSW12_RS25715 66cadcc14d44944360f2e331483ff411 211 SUPERFAMILY SSF54980 135 200 5.04E-11 T 29-03-2018 IPR035647 EF-G domain III/V-like CSW12_RS24865 e8e54a5261023ca304ea8486c568d26c 252 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 2 70 8.1E-21 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CSW12_RS24865 e8e54a5261023ca304ea8486c568d26c 252 Pfam PF11495 Archaeal transcriptional regulator TrmB 102 222 7.0E-6 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal CSW12_RS24865 e8e54a5261023ca304ea8486c568d26c 252 SUPERFAMILY SSF46785 1 70 3.83E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24865 e8e54a5261023ca304ea8486c568d26c 252 Gene3D G3DSA:1.10.10.10 1 85 1.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24865 e8e54a5261023ca304ea8486c568d26c 252 Gene3D G3DSA:3.30.870.10 86 222 8.6E-4 T 29-03-2018 CSW12_RS05110 af5887f4f94c46128588242ee32bb8fb 179 Gene3D G3DSA:3.40.50.10130 20 176 2.2E-22 T 29-03-2018 CSW12_RS05110 af5887f4f94c46128588242ee32bb8fb 179 SUPERFAMILY SSF52980 20 162 1.23E-14 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS05110 af5887f4f94c46128588242ee32bb8fb 179 SMART SM00891 21 116 5.2E-13 T 29-03-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 CSW12_RS05110 af5887f4f94c46128588242ee32bb8fb 179 Pfam PF02732 ERCC4 domain 24 162 8.8E-14 T 29-03-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 CSW12_RS04810 6f63c6f976af142f6f175f136dde8f87 368 SUPERFAMILY SSF56300 145 366 2.23E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS04810 6f63c6f976af142f6f175f136dde8f87 368 Pfam PF00149 Calcineurin-like phosphoesterase 148 311 2.6E-12 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS04810 6f63c6f976af142f6f175f136dde8f87 368 Gene3D G3DSA:3.60.21.10 146 349 2.9E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 214 8.0E-43 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 Gene3D G3DSA:3.40.50.10090 257 428 1.7E-6 T 29-03-2018 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 PIRSF PIRSF036426 1 255 2.2E-96 T 29-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 Gene3D G3DSA:3.30.950.10 128 256 1.2E-34 T 29-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 238 1.3E-90 T 29-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 83 116 - T 29-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 Gene3D G3DSA:3.40.1010.10 2 127 8.0E-32 T 29-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 SUPERFAMILY SSF69618 252 329 1.96E-6 T 29-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CSW12_RS17210 6eeae6356785b08040543b872da30c09 474 SUPERFAMILY SSF53790 1 252 1.19E-74 T 29-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CSW12_RS08765 7c8fed4532897b40c1c375171b34b9cf 300 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 4.1E-29 T 29-03-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal CSW12_RS08765 7c8fed4532897b40c1c375171b34b9cf 300 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 4 289 2.0E-146 T 29-03-2018 IPR014215 Dipicolinic acid synthetase subunit A CSW12_RS08765 7c8fed4532897b40c1c375171b34b9cf 300 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 151 289 5.0E-10 T 29-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CSW12_RS08765 7c8fed4532897b40c1c375171b34b9cf 300 Gene3D G3DSA:3.40.50.720 137 272 3.3E-21 T 29-03-2018 CSW12_RS08765 7c8fed4532897b40c1c375171b34b9cf 300 SUPERFAMILY SSF51735 131 269 1.4E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS08765 7c8fed4532897b40c1c375171b34b9cf 300 Gene3D G3DSA:3.40.50.720 1 136 9.6E-6 T 29-03-2018 CSW12_RS05935 3011fdce27fa9c2c04b9bce9df3daa94 195 Gene3D G3DSA:2.60.40.10 39 193 1.2E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS05935 3011fdce27fa9c2c04b9bce9df3daa94 195 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 13 44 4.6E-11 T 29-03-2018 IPR023833 Signal peptide, camelysin CSW12_RS05935 3011fdce27fa9c2c04b9bce9df3daa94 195 Pfam PF12389 Camelysin metallo-endopeptidase 2 194 1.5E-87 T 29-03-2018 IPR022121 Peptidase M73, camelysin CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 Pfam PF07508 Recombinase 172 260 4.9E-15 T 29-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 Pfam PF00239 Resolvase, N terminal domain 4 149 9.5E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 Gene3D G3DSA:1.20.5.40 121 149 1.2E-8 T 29-03-2018 CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 SUPERFAMILY SSF53041 1 149 6.41E-38 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 SMART SM00857 3 151 3.7E-60 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 Pfam PF13408 Recombinase zinc beta ribbon domain 274 332 4.5E-11 T 29-03-2018 IPR025827 Recombinase zinc beta ribbon domain CSW12_RS05045 8ef29fb30e48fb222618643cc8b7fd43 467 Gene3D G3DSA:3.40.50.1390 1 120 7.7E-40 T 29-03-2018 CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 8.1E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 8.1E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 8.1E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 Pfam PF01047 MarR family 40 97 5.7E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 Gene3D G3DSA:1.10.10.10 1 148 3.2E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 SMART SM00347 33 133 5.2E-30 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06225 9ec223aec35139e9071ac147ae4801f2 148 SUPERFAMILY SSF46785 8 145 3.77E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19015 7377905204228a7818f06424f2929da5 321 SUPERFAMILY SSF103481 44 150 6.93E-10 T 29-03-2018 CSW12_RS19015 7377905204228a7818f06424f2929da5 321 SUPERFAMILY SSF103481 214 302 1.31E-9 T 29-03-2018 CSW12_RS19015 7377905204228a7818f06424f2929da5 321 Pfam PF00892 EamA-like transporter family 7 148 6.0E-24 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS19015 7377905204228a7818f06424f2929da5 321 Pfam PF00892 EamA-like transporter family 161 300 5.8E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 Gene3D G3DSA:3.40.50.720 1 179 5.9E-42 T 29-03-2018 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 3.2E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 3.2E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 3.2E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 3.2E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 3.2E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 3.2E-47 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 4.8E-57 T 29-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.147 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 SUPERFAMILY SSF51735 3 179 2.02E-59 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07130 1277e154159be6984b2a068b71016358 340 Gene3D G3DSA:1.10.1040.10 181 331 1.6E-56 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 SUPERFAMILY SSF48179 181 332 9.52E-59 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 1.3E-55 T 29-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS07130 1277e154159be6984b2a068b71016358 340 PIRSF PIRSF000114 1 333 9.5E-111 T 29-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CSW12_RS04975 f9322be1698078e63bd08261dfbd765b 92 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 39 86 2.3E-7 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS04975 f9322be1698078e63bd08261dfbd765b 92 SUPERFAMILY SSF47789 39 92 1.83E-12 T 29-03-2018 CSW12_RS04975 f9322be1698078e63bd08261dfbd765b 92 Gene3D G3DSA:1.10.150.20 36 92 6.5E-14 T 29-03-2018 CSW12_RS04975 f9322be1698078e63bd08261dfbd765b 92 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 49 92 0.001 T 29-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 72 85 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 114 128 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 572 588 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 424 438 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 508 525 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 528 540 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 37 52 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 490 506 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR00418 DNA topoisomerase II family signature 268 281 2.2E-69 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Gene3D G3DSA:3.30.230.10 222 394 2.1E-56 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 SUPERFAMILY SSF56719 398 633 4.71E-86 T 29-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 SUPERFAMILY SSF54211 222 392 8.54E-55 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Gene3D G3DSA:3.30.565.10 20 221 4.7E-71 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 632 1.4E-266 T 29-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 176 1.1E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 SUPERFAMILY SSF55874 7 219 4.06E-69 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 6 638 48.571 T 29-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF01751 Toprim domain 423 523 5.5E-16 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 7 642 0.0 T 29-03-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 29-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Gene3D G3DSA:3.40.50.670 404 636 4.0E-94 T 29-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 SMART SM00387 33 177 2.0E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 376 396 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 182 197 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 362 376 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 221 243 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 312 328 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 PRINTS PR01159 DNA gyrase subunit B signature 197 210 1.9E-60 T 29-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 629 7.6E-30 T 29-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 SMART SM00433 37 633 0.0 T 29-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS09760 f0f73b61d2ef69659be88254cce11fc7 654 Pfam PF00204 DNA gyrase B 222 392 1.7E-58 T 29-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CSW12_RS20170 87936c0c6cf3880a8f479bfc68b5dfb5 259 Gene3D G3DSA:3.40.50.1110 51 257 5.3E-26 T 29-03-2018 CSW12_RS20170 87936c0c6cf3880a8f479bfc68b5dfb5 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 57 244 1.2E-19 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS20170 87936c0c6cf3880a8f479bfc68b5dfb5 259 SUPERFAMILY SSF52266 56 254 6.62E-31 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 183 9.9E-45 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 4 183 2.0E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 Gene3D G3DSA:3.40.50.1000 75 220 4.7E-29 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 2.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 2.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 2.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 Gene3D G3DSA:1.10.150.240 15 74 9.3E-10 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS20605 184e97a161e5f9e03337335eb3825f6f 221 SUPERFAMILY SSF56784 2 214 1.18E-51 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS09470 9b6f81593acc733768bf793c60f82a00 195 Gene3D G3DSA:3.40.50.300 5 193 2.5E-13 T 29-03-2018 CSW12_RS09470 9b6f81593acc733768bf793c60f82a00 195 SUPERFAMILY SSF52540 5 190 3.76E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09470 9b6f81593acc733768bf793c60f82a00 195 Pfam PF13521 AAA domain 8 179 1.1E-12 T 29-03-2018 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 TIGRFAM TIGR00861 MIP: MIP family channel proteins 7 230 1.7E-63 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 Pfam PF00230 Major intrinsic protein 3 230 2.1E-47 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 ProSitePatterns PS00221 MIP family signature. 62 70 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 Gene3D G3DSA:1.20.1080.10 1 242 2.0E-85 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 2 21 6.1E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 81 100 6.1E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 44 68 6.1E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 136 154 6.1E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 213 233 6.1E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 PRINTS PR00783 Major intrinsic protein family signature 166 188 6.1E-53 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS04460 7ede0d2ea4b9bd77c23fdec3a9e90145 273 SUPERFAMILY SSF81338 2 234 1.83E-73 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 Gene3D G3DSA:1.10.275.10 1 94 6.0E-25 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 263 279 9.9E-10 T 29-03-2018 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 89 111 9.9E-10 T 29-03-2018 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 218 242 9.9E-10 T 29-03-2018 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00145 Argininosuccinate lyase family signature 130 150 9.9E-10 T 29-03-2018 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 Gene3D G3DSA:1.20.200.10 95 350 6.9E-82 T 29-03-2018 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 430 1.2E-182 T 29-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 2.0E-26 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 263 279 2.0E-26 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 90 108 2.0E-26 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 PRINTS PR00149 Fumarate lyase superfamily signature 218 245 2.0E-26 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 Pfam PF00206 Lyase 6 288 5.7E-76 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 ProSitePatterns PS00163 Fumarate lyases signature. 263 272 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 SMART SM00998 351 431 5.6E-41 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 Pfam PF10397 Adenylosuccinate lyase C-terminus 352 429 3.1E-26 T 29-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 SUPERFAMILY SSF48557 3 429 1.05E-140 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS00030 32a497982f25b13a0ffb875fb7a58f98 435 Gene3D G3DSA:1.10.40.30 351 430 1.9E-27 T 29-03-2018 CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 12 19 - T 29-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 SUPERFAMILY SSF55594 3 82 5.89E-27 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 12 28 6.6E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 37 52 6.6E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 PRINTS PR00107 Phosphocarrier protein signature 52 69 6.6E-24 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 Gene3D G3DSA:3.30.1340.10 1 81 4.4E-32 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 80 6.6E-31 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS07440 48008f36b23ef60c873996270d2019b1 87 Pfam PF00381 PTS HPr component phosphorylation site 2 81 2.2E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 Gene3D G3DSA:1.10.1740.10 1 97 1.7E-21 T 29-03-2018 CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 SUPERFAMILY SSF88946 3 98 4.91E-22 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 Pfam PF08281 Sigma-70, region 4 115 165 1.9E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 169 2.1E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 SUPERFAMILY SSF88659 88 172 3.18E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 Pfam PF04542 Sigma-70 region 2 14 83 1.7E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS01930 7bb78a1249e1ee566827b24df73a52fa 185 Gene3D G3DSA:1.10.10.10 98 184 2.8E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00685 895bc29a0c534ec33a360f086ddd1c08 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS00685 895bc29a0c534ec33a360f086ddd1c08 240 SUPERFAMILY SSF52540 1 235 6.14E-79 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00685 895bc29a0c534ec33a360f086ddd1c08 240 PIRSF PIRSF039085 1 240 3.9E-117 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CSW12_RS00685 895bc29a0c534ec33a360f086ddd1c08 240 Pfam PF00005 ABC transporter 17 165 1.2E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS00685 895bc29a0c534ec33a360f086ddd1c08 240 Gene3D G3DSA:3.40.50.300 1 239 3.6E-75 T 29-03-2018 CSW12_RS00685 895bc29a0c534ec33a360f086ddd1c08 240 SMART SM00382 26 213 7.3E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14380 f0673543413def651b040085b92d786d 407 SMART SM00422 1 68 1.1E-5 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS14380 f0673543413def651b040085b92d786d 407 SUPERFAMILY SSF46955 1 114 5.13E-15 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS14380 f0673543413def651b040085b92d786d 407 Gene3D G3DSA:1.10.1660.10 1 56 7.1E-9 T 29-03-2018 CSW12_RS14380 f0673543413def651b040085b92d786d 407 Pfam PF13411 MerR HTH family regulatory protein 1 65 3.2E-9 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS14380 f0673543413def651b040085b92d786d 407 SUPERFAMILY SSF53335 223 342 7.73E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS14380 f0673543413def651b040085b92d786d 407 Gene3D G3DSA:2.20.25.10 134 176 0.0011 T 29-03-2018 CSW12_RS14380 f0673543413def651b040085b92d786d 407 Gene3D G3DSA:1.10.1660.10 57 123 6.9E-5 T 29-03-2018 CSW12_RS14380 f0673543413def651b040085b92d786d 407 Pfam PF13847 Methyltransferase domain 229 332 1.4E-7 T 29-03-2018 IPR025714 Methyltransferase domain CSW12_RS14380 f0673543413def651b040085b92d786d 407 Gene3D G3DSA:3.40.50.150 214 382 4.2E-13 T 29-03-2018 CSW12_RS13130 7a85995b028c3bf594c824907e5e8167 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 2.3E-20 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13130 7a85995b028c3bf594c824907e5e8167 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 8.9E-25 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS20805 c19d4c1793d0aeef6ba889586095773d 151 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 25 1.5E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CSW12_RS20805 c19d4c1793d0aeef6ba889586095773d 151 PIRSF PIRSF021292 1 144 2.9E-55 T 29-03-2018 IPR016785 ComG operon protein 4 GO:0030420 CSW12_RS20805 c19d4c1793d0aeef6ba889586095773d 151 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 26 4.1E-5 T 29-03-2018 IPR012902 Prokaryotic N-terminal methylation site CSW12_RS20805 c19d4c1793d0aeef6ba889586095773d 151 Gene3D G3DSA:3.30.700.10 6 145 1.5E-4 T 29-03-2018 CSW12_RS20805 c19d4c1793d0aeef6ba889586095773d 151 SUPERFAMILY SSF54523 6 128 5.96E-10 T 29-03-2018 CSW12_RS24910 1c2a6bcf04e7c964168e7e854190a111 173 SUPERFAMILY SSF55729 3 169 6.82E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS24910 1c2a6bcf04e7c964168e7e854190a111 173 Pfam PF13302 Acetyltransferase (GNAT) domain 7 145 1.0E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS24910 1c2a6bcf04e7c964168e7e854190a111 173 Gene3D G3DSA:3.40.630.30 1 172 1.2E-23 T 29-03-2018 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 29-03-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 9.0E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 9.0E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 9.0E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 9.0E-16 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 Gene3D G3DSA:1.20.5.1150 16 52 4.0E-18 T 29-03-2018 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.633 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 1.6E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 Pfam PF01165 Ribosomal protein S21 5 57 5.2E-21 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21160 26ae892bde23897c189a91b0a25be68e 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 1.0E-8 T 29-03-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS02790 8854162bbf39bc964a1cb243bdd5cc21 306 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 285 4.3E-81 T 29-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CSW12_RS02790 8854162bbf39bc964a1cb243bdd5cc21 306 SUPERFAMILY SSF161098 16 275 1.27E-39 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS02790 8854162bbf39bc964a1cb243bdd5cc21 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 291 1.6E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS02790 8854162bbf39bc964a1cb243bdd5cc21 306 Gene3D G3DSA:1.10.3720.10 2 280 9.4E-39 T 29-03-2018 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 Gene3D G3DSA:1.20.1250.20 1 193 1.7E-34 T 29-03-2018 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 SUPERFAMILY SSF103473 6 389 4.19E-57 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 385 1.3E-70 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 71 93 1.1E-8 T 29-03-2018 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 11 35 1.1E-8 T 29-03-2018 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 1.1E-8 T 29-03-2018 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 Pfam PF07690 Major Facilitator Superfamily 21 350 2.2E-41 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 Gene3D G3DSA:1.20.1250.20 194 398 4.1E-11 T 29-03-2018 CSW12_RS10635 da37130028d1878a9e8a0e5f4b771b19 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS17060 4114e561249ae3714e7b26b3c727c5b0 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 4.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS17060 4114e561249ae3714e7b26b3c727c5b0 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 4.6E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS17060 4114e561249ae3714e7b26b3c727c5b0 194 SUPERFAMILY SSF46689 3 65 2.79E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS17060 4114e561249ae3714e7b26b3c727c5b0 194 Gene3D G3DSA:1.10.10.60 45 189 1.8E-9 T 29-03-2018 CSW12_RS17060 4114e561249ae3714e7b26b3c727c5b0 194 Gene3D G3DSA:1.10.10.60 2 44 1.1E-14 T 29-03-2018 CSW12_RS17060 4114e561249ae3714e7b26b3c727c5b0 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 3.9E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 SMART SM00304 185 237 7.8E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 SUPERFAMILY SSF55874 294 458 9.17E-44 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 8.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 SUPERFAMILY SSF47384 221 303 3.34E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 2.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 2.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 2.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 2.8E-18 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 Gene3D G3DSA:1.10.287.130 228 299 2.1E-16 T 29-03-2018 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 Gene3D G3DSA:3.30.565.10 311 458 3.0E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 SMART SM00387 348 458 1.3E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 SUPERFAMILY SSF158472 186 235 2.22E-11 T 29-03-2018 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 Pfam PF00672 HAMP domain 186 233 2.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 457 2.1E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS11630 b8bcd672ac577723e7534370c67e86cb 458 SMART SM00388 238 304 6.0E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS26670 0fa20371b0cadb220649bb6efea18fe0 61 SUPERFAMILY SSF55331 2 60 3.93E-20 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CSW12_RS26670 0fa20371b0cadb220649bb6efea18fe0 61 Pfam PF01361 Tautomerase enzyme 2 60 8.3E-25 T 29-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CSW12_RS26670 0fa20371b0cadb220649bb6efea18fe0 61 Gene3D G3DSA:3.30.429.10 1 61 2.8E-22 T 29-03-2018 CSW12_RS26670 0fa20371b0cadb220649bb6efea18fe0 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 2.3E-27 T 29-03-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CSW12_RS10745 89f00ed47f8b69719baa841d5969eed4 253 Pfam PF00005 ABC transporter 21 162 4.1E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS10745 89f00ed47f8b69719baa841d5969eed4 253 SMART SM00382 30 219 2.7E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS10745 89f00ed47f8b69719baa841d5969eed4 253 SUPERFAMILY SSF52540 5 223 7.5E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS10745 89f00ed47f8b69719baa841d5969eed4 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS10745 89f00ed47f8b69719baa841d5969eed4 253 Gene3D G3DSA:3.40.50.300 2 242 1.3E-64 T 29-03-2018 CSW12_RS00865 4e287a697b7d7fbfd8f8946cc05702bc 427 Gene3D G3DSA:1.20.1250.20 12 209 1.1E-8 T 29-03-2018 CSW12_RS00865 4e287a697b7d7fbfd8f8946cc05702bc 427 Gene3D G3DSA:1.20.1250.20 221 416 7.0E-24 T 29-03-2018 CSW12_RS00865 4e287a697b7d7fbfd8f8946cc05702bc 427 Pfam PF11700 Vacuole effluxer Atg22 like 138 413 2.2E-49 T 29-03-2018 IPR024671 Autophagy-related protein 22-like CSW12_RS00865 4e287a697b7d7fbfd8f8946cc05702bc 427 Pfam PF11700 Vacuole effluxer Atg22 like 48 131 2.2E-9 T 29-03-2018 IPR024671 Autophagy-related protein 22-like CSW12_RS00865 4e287a697b7d7fbfd8f8946cc05702bc 427 SUPERFAMILY SSF103473 16 413 1.7E-37 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 Pfam PF00005 ABC transporter 323 469 2.6E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 Pfam PF00005 ABC transporter 29 179 2.2E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 SUPERFAMILY SSF52540 10 243 1.33E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 SUPERFAMILY SSF52540 300 536 3.73E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 Pfam PF12558 ATP-binding cassette cobalt transporter 243 314 3.2E-15 T 29-03-2018 IPR022216 ABC cobalt transporter GO:0016820 CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 SMART SM00382 38 230 1.3E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 SMART SM00382 332 517 2.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 Gene3D G3DSA:3.40.50.300 302 548 1.2E-61 T 29-03-2018 CSW12_RS14530 1625c42ef26aa18493e3c2bf7ae7851d 573 Gene3D G3DSA:3.40.50.300 7 249 1.6E-58 T 29-03-2018 CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 Pfam PF00005 ABC transporter 26 183 2.5E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 Gene3D G3DSA:3.40.50.300 2 336 6.1E-81 T 29-03-2018 CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 4.6E-23 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 SUPERFAMILY SSF52540 5 255 1.12E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 292 4.2E-16 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS02005 8721b1da58ef433d2da230782bb12fdb 339 SMART SM00382 34 241 2.6E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14715 7ef9a46c83b03f0cbeea0f196b740c97 256 Pfam PF00005 ABC transporter 24 170 1.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14715 7ef9a46c83b03f0cbeea0f196b740c97 256 SUPERFAMILY SSF52540 3 224 9.44E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14715 7ef9a46c83b03f0cbeea0f196b740c97 256 SMART SM00382 31 226 1.9E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14715 7ef9a46c83b03f0cbeea0f196b740c97 256 Gene3D G3DSA:3.40.50.300 1 241 2.8E-62 T 29-03-2018 CSW12_RS12230 b56198d25286a0d467f89cbe75c672b8 144 SUPERFAMILY SSF47240 10 139 1.09E-29 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS12230 b56198d25286a0d467f89cbe75c672b8 144 Pfam PF02915 Rubrerythrin 21 133 7.4E-10 T 29-03-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CSW12_RS12230 b56198d25286a0d467f89cbe75c672b8 144 Gene3D G3DSA:1.20.1260.10 7 82 1.3E-11 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS12230 b56198d25286a0d467f89cbe75c672b8 144 Gene3D G3DSA:1.20.1260.10 83 143 1.2E-12 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS13850 2e0db23b5207a6d484252adc4f7bebab 112 Pfam PF07978 NIPSNAP 8 77 2.6E-8 T 29-03-2018 IPR012577 NIPSNAP CSW12_RS13850 2e0db23b5207a6d484252adc4f7bebab 112 SUPERFAMILY SSF54909 1 107 5.09E-13 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS13850 2e0db23b5207a6d484252adc4f7bebab 112 Gene3D G3DSA:3.30.70.100 1 108 4.2E-15 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 SUPERFAMILY SSF49478 475 536 5.1E-7 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 SUPERFAMILY SSF49478 565 615 5.49E-9 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 92 130 3.4E-9 T 29-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 SUPERFAMILY SSF49478 655 722 4.32E-5 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 Gene3D G3DSA:2.60.40.810 636 732 2.9E-22 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 Gene3D G3DSA:2.60.40.810 369 458 5.4E-24 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 Gene3D G3DSA:2.60.40.810 270 368 5.7E-23 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 Gene3D G3DSA:2.60.40.810 459 553 5.1E-20 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 Gene3D G3DSA:2.60.40.810 733 866 3.5E-24 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 Gene3D G3DSA:2.60.40.10 554 635 1.2E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 868 904 1.8E-5 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 SUPERFAMILY SSF49478 296 360 2.2E-7 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 SUPERFAMILY SSF49478 748 810 1.33E-8 T 29-03-2018 CSW12_RS30885 8ea7b79112adeabde38e00c25db14a64 906 SUPERFAMILY SSF49478 385 445 3.34E-7 T 29-03-2018 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 Gene3D G3DSA:1.20.1640.10 484 724 8.8E-26 T 29-03-2018 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 Gene3D G3DSA:1.20.1640.10 153 360 3.6E-31 T 29-03-2018 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 Pfam PF03176 MMPL family 496 730 1.5E-45 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 Pfam PF03176 MMPL family 51 405 6.0E-60 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 PRINTS PR00702 Acriflavin resistance protein family signature 195 218 8.5E-5 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 8.5E-5 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 SUPERFAMILY SSF82866 176 360 3.66E-28 T 29-03-2018 CSW12_RS16005 078b7ad54aafff8d0cb502ecc7ecd276 743 SUPERFAMILY SSF82866 543 728 3.27E-27 T 29-03-2018 CSW12_RS08915 46c432b56cd59592d215feec3fa5302e 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 274 1.9E-97 T 29-03-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate CSW12_RS08915 46c432b56cd59592d215feec3fa5302e 288 SUPERFAMILY SSF52518 12 286 1.52E-79 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS08915 46c432b56cd59592d215feec3fa5302e 288 Gene3D G3DSA:3.40.50.970 5 72 6.3E-16 T 29-03-2018 CSW12_RS08915 46c432b56cd59592d215feec3fa5302e 288 Gene3D G3DSA:3.40.50.970 73 288 4.1E-50 T 29-03-2018 CSW12_RS08915 46c432b56cd59592d215feec3fa5302e 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 1.5E-32 T 29-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CSW12_RS08915 46c432b56cd59592d215feec3fa5302e 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 7.9E-23 T 29-03-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 Gene3D G3DSA:1.10.260.40 3 55 1.4E-25 T 29-03-2018 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 SMART SM00354 2 72 1.2E-39 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 SUPERFAMILY SSF47413 2 60 8.44E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.8E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.3E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.3E-6 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 29-03-2018 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 SUPERFAMILY SSF53822 62 332 2.55E-90 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 Gene3D G3DSA:3.40.50.2300 176 314 3.0E-45 T 29-03-2018 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 Gene3D G3DSA:3.40.50.2300 56 175 1.2E-35 T 29-03-2018 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 332 9.8E-166 T 29-03-2018 IPR006377 Catabolite control protein A GO:0006355 CSW12_RS23040 3d18046ad35b71aaa00bea67191a6752 332 Pfam PF13377 Periplasmic binding protein-like domain 170 331 4.3E-37 T 29-03-2018 CSW12_RS00985 568e6427bd8773f60b1518b989e42151 142 Pfam PF00892 EamA-like transporter family 3 140 9.7E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS00985 568e6427bd8773f60b1518b989e42151 142 SUPERFAMILY SSF103481 38 141 8.76E-14 T 29-03-2018 CSW12_RS18685 7355d19c405079585299e92ac080e5e1 275 Gene3D G3DSA:3.30.460.10 3 142 1.4E-16 T 29-03-2018 CSW12_RS18685 7355d19c405079585299e92ac080e5e1 275 SUPERFAMILY SSF81301 9 86 4.09E-8 T 29-03-2018 CSW12_RS18685 7355d19c405079585299e92ac080e5e1 275 Pfam PF13228 Domain of unknown function (DUF4037) 117 210 5.4E-12 T 29-03-2018 IPR025117 Domain of unknown function DUF4037 CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 SUPERFAMILY SSF103501 13 238 3.01E-15 T 29-03-2018 IPR023234 NarG-like domain CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 Gene3D G3DSA:1.10.1060.10 244 405 2.9E-33 T 29-03-2018 CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 Pfam PF02754 Cysteine-rich domain 460 543 1.9E-6 T 29-03-2018 IPR004017 Cysteine-rich domain CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 Pfam PF02754 Cysteine-rich domain 582 669 1.2E-17 T 29-03-2018 IPR004017 Cysteine-rich domain CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 SUPERFAMILY SSF46548 252 313 1.46E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 SUPERFAMILY SSF46548 354 400 1.46E-20 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 372 383 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 Gene3D G3DSA:1.20.950.20 4 237 1.9E-45 T 29-03-2018 CSW12_RS26520 33ac39e2d877fbc3246b4ca9fd97d79d 703 Pfam PF13183 4Fe-4S dicluster domain 274 384 2.6E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 Gene3D G3DSA:3.30.43.10 2 95 1.7E-24 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 Gene3D G3DSA:3.30.465.10 96 238 4.5E-40 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 Pfam PF01565 FAD binding domain 43 179 1.8E-39 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 Gene3D G3DSA:1.10.45.10 418 456 4.9E-12 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 456 3.8E-56 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 SUPERFAMILY SSF56176 4 217 3.46E-65 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS10375 6191c1a2e74ecb14108310dd78b1491f 463 SUPERFAMILY SSF55103 220 457 7.52E-62 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CSW12_RS10680 231f6e6433f98f78ff81d3fac9a3cbc4 117 SUPERFAMILY SSF54593 4 115 4.09E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS10680 231f6e6433f98f78ff81d3fac9a3cbc4 117 Gene3D G3DSA:3.10.180.10 1 116 2.3E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 Gene3D G3DSA:3.40.50.1370 2 147 1.3E-56 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 Gene3D G3DSA:3.40.50.1370 148 314 6.0E-59 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 9.1E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 9.1E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 288 299 9.1E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 9.1E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 9.1E-30 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 310 80.991 T 29-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 307 8.4E-56 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 SUPERFAMILY SSF53671 9 311 4.58E-108 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 309 7.7E-130 T 29-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 148 5.3E-51 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 262 271 7.2E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 7.2E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 297 7.2E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS20190 4fa94fcdf14ecfd3cdfe7ca01e16dab9 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.2E-26 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 Gene3D G3DSA:1.10.1740.10 2 68 1.8E-16 T 29-03-2018 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 SUPERFAMILY SSF88659 80 157 3.92E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 Gene3D G3DSA:1.10.10.10 69 154 1.2E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 Gene3D G3DSA:3.10.450.50 155 286 3.0E-7 T 29-03-2018 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 Pfam PF04542 Sigma-70 region 2 6 71 8.3E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 6 285 2.9E-123 T 29-03-2018 IPR014303 RNA polymerase sigma-70, ECF type CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 160 2.3E-22 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 Pfam PF08281 Sigma-70, region 4 106 156 4.4E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 SUPERFAMILY SSF88946 4 91 4.87E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS15790 3a7a24497e86c9f1f5d8658cd04fbe18 289 SUPERFAMILY SSF54427 169 285 7.42E-8 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS08135 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 Pfam PF01783 Ribosomal L32p protein family 2 57 4.9E-27 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08135 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 56 2.8E-28 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08135 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.023 T 29-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08135 d2c8a2d9d3b25b17f80a4dcc54dfe089 57 SUPERFAMILY SSF57829 1 55 5.31E-22 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CSW12_RS29445 94d84ac86f75fec6805062801bacc642 228 Gene3D G3DSA:3.30.420.10 61 214 9.3E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29445 94d84ac86f75fec6805062801bacc642 228 Pfam PF13610 DDE domain 71 206 4.4E-44 T 29-03-2018 IPR032874 DDE domain CSW12_RS29445 94d84ac86f75fec6805062801bacc642 228 SUPERFAMILY SSF53098 70 190 4.93E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS08200 5d0fc4a70d04f8068523e6bcdbb94e05 363 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 6 360 6.6E-131 T 29-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CSW12_RS08200 5d0fc4a70d04f8068523e6bcdbb94e05 363 Pfam PF01098 Cell cycle protein 9 362 1.0E-125 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CSW12_RS08200 5d0fc4a70d04f8068523e6bcdbb94e05 363 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 319 343 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CSW12_RS08200 5d0fc4a70d04f8068523e6bcdbb94e05 363 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 6 359 3.5E-173 T 29-03-2018 IPR013438 Sporulation stage V, protein E CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF13414 TPR repeat 49 82 3.9E-8 T 29-03-2018 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SUPERFAMILY SSF48452 8 212 8.72E-41 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.20.58.280 179 217 1.8E-9 T 29-03-2018 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF13181 Tetratricopeptide repeat 141 170 0.0035 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 1 34 15.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 171 204 2.4E-6 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 103 136 0.62 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 137 170 0.039 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 69 102 0.059 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 SMART SM00028 35 68 0.0021 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.25.40.10 54 90 2.2E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.10.8.10 171 178 0.01 T 29-03-2018 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.25.40.10 5 53 9.1E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF00515 Tetratricopeptide repeat 171 204 5.0E-8 T 29-03-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.25.40.10 91 140 3.3E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Gene3D G3DSA:1.25.40.10 141 170 4.5E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF07719 Tetratricopeptide repeat 8 34 1.4E-5 T 29-03-2018 IPR013105 Tetratricopeptide repeat 2 CSW12_RS21610 f773ab155dd23a0fbab8c546f70a9d67 219 Pfam PF13176 Tetratricopeptide repeat 108 138 0.024 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS26415 db3342eb79259280bd0e8fcc2dbcfa86 346 Gene3D G3DSA:3.90.870.10 8 218 5.4E-81 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CSW12_RS26415 db3342eb79259280bd0e8fcc2dbcfa86 346 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 340 8.9E-29 T 29-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CSW12_RS26415 db3342eb79259280bd0e8fcc2dbcfa86 346 PIRSF PIRSF004930 1 346 2.1E-135 T 29-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CSW12_RS26415 db3342eb79259280bd0e8fcc2dbcfa86 346 Pfam PF01300 Telomere recombination 27 202 5.5E-58 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CSW12_RS26415 db3342eb79259280bd0e8fcc2dbcfa86 346 SUPERFAMILY SSF55821 19 214 5.8E-68 T 29-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CSW12_RS26415 db3342eb79259280bd0e8fcc2dbcfa86 346 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 213 2.8E-65 T 29-03-2018 IPR006070 YrdC-like domain GO:0003725 CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 Pfam PF00271 Helicase conserved C-terminal domain 232 329 6.2E-25 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 Gene3D G3DSA:3.40.50.300 3 212 3.3E-51 T 29-03-2018 CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 SUPERFAMILY SSF52540 66 347 6.17E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 Gene3D G3DSA:3.40.50.300 213 362 3.4E-37 T 29-03-2018 CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 SMART SM00490 248 329 7.7E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 SMART SM00487 17 213 1.5E-51 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS17360 981ac9af97dd8cb4677e8a4f7f126a2a 389 Pfam PF00270 DEAD/DEAH box helicase 22 186 1.0E-42 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS09730 8d0f2b12f495b85e29bf23e5d420a29e 618 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 28 617 1.1E-220 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CSW12_RS09730 8d0f2b12f495b85e29bf23e5d420a29e 618 Gene3D G3DSA:3.20.70.20 34 599 8.9E-204 T 29-03-2018 CSW12_RS09730 8d0f2b12f495b85e29bf23e5d420a29e 618 SUPERFAMILY SSF51998 30 596 3.52E-161 T 29-03-2018 CSW12_RS09730 8d0f2b12f495b85e29bf23e5d420a29e 618 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 29 617 2.3E-208 T 29-03-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 SMART SM00411 1 90 6.3E-44 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 SUPERFAMILY SSF47729 1 90 5.15E-33 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 5.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 5.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 5.3E-19 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 Gene3D G3DSA:4.10.520.10 1 91 5.3E-35 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CSW12_RS30355 66676878f160f693650c090b8d5167fd 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.6E-34 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 SUPERFAMILY SSF52467 198 317 2.12E-48 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 1.5E-35 T 29-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 PIRSF PIRSF000089 1 323 2.8E-113 T 29-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 Gene3D G3DSA:3.40.50.620 1 194 8.0E-47 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 29-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 SUPERFAMILY SSF52402 4 191 2.58E-50 T 29-03-2018 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 SMART SM00893 5 195 7.0E-46 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 Pfam PF01012 Electron transfer flavoprotein domain 5 179 4.2E-43 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CSW12_RS22205 e1a4958bd67b0b19d03738a616c277d9 325 Gene3D G3DSA:3.40.50.1220 195 324 9.2E-59 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 SMART SM00345 19 78 6.7E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 Gene3D G3DSA:3.40.640.10 121 366 4.0E-34 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 6.1E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 Gene3D G3DSA:1.10.10.10 3 80 7.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 SUPERFAMILY SSF53383 84 462 2.14E-79 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 Gene3D G3DSA:3.90.1150.10 367 464 1.9E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 1.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 1.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 Pfam PF00155 Aminotransferase class I and II 115 414 1.2E-15 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS17465 c2bf8750bcd327eb6128b13c250995f6 471 SUPERFAMILY SSF46785 8 84 2.73E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20555 9daa8c01407c8566a745a960d717d6c7 308 Gene3D G3DSA:3.40.50.300 86 257 1.4E-9 T 29-03-2018 CSW12_RS20555 9daa8c01407c8566a745a960d717d6c7 308 SUPERFAMILY SSF52540 23 260 4.96E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20555 9daa8c01407c8566a745a960d717d6c7 308 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 26 292 2.8E-122 T 29-03-2018 IPR014217 Sporulation stage III, protein AA CSW12_RS20555 9daa8c01407c8566a745a960d717d6c7 308 SMART SM00382 133 282 1.8E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05310 3829c0054ea091f3dda93fefd1a3ff88 163 SUPERFAMILY SSF89963 91 163 1.41E-25 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CSW12_RS05310 3829c0054ea091f3dda93fefd1a3ff88 163 Gene3D G3DSA:3.30.70.990 13 98 1.8E-31 T 29-03-2018 IPR035570 UPF0234 N-terminal domain CSW12_RS05310 3829c0054ea091f3dda93fefd1a3ff88 163 Gene3D G3DSA:3.30.70.860 99 163 6.0E-29 T 29-03-2018 IPR035571 UPF0234/UPF0381 domain CSW12_RS05310 3829c0054ea091f3dda93fefd1a3ff88 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.975 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CSW12_RS05310 3829c0054ea091f3dda93fefd1a3ff88 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.8E-62 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CSW12_RS05310 3829c0054ea091f3dda93fefd1a3ff88 163 SUPERFAMILY SSF89963 6 90 1.07E-30 T 29-03-2018 IPR007551 Protein of unknown function DUF520 CSW12_RS09450 4e5d14e0072c531036d7b79a4c9e6b3c 168 PIRSF PIRSF021441 1 161 2.4E-73 T 29-03-2018 IPR031306 CcdC protein CSW12_RS09450 4e5d14e0072c531036d7b79a4c9e6b3c 168 Pfam PF07301 Protein of unknown function (DUF1453) 6 149 3.6E-61 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 PIRSF PIRSF000857 3 234 1.8E-88 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 43 231 3.6E-71 T 29-03-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 Gene3D G3DSA:3.40.50.620 3 234 1.3E-44 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 232 3.5E-88 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 42.403 T 29-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 SUPERFAMILY SSF52402 16 197 1.57E-50 T 29-03-2018 CSW12_RS06685 8aa0faa5819c3fbab8f0e1bb354b93dc 234 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 37 209 2.5E-49 T 29-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CSW12_RS28130 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 Pfam PF00005 ABC transporter 43 190 9.8E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28130 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 27 294 2.9E-119 T 29-03-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 CSW12_RS28130 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 Gene3D G3DSA:3.40.50.300 21 264 6.3E-71 T 29-03-2018 CSW12_RS28130 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 SMART SM00382 52 238 6.4E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28130 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 SUPERFAMILY SSF52540 26 252 3.96E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28130 ae9bf09eceb8b65ef5a1d107ffdf60a8 300 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS13005 95c1578fc95601c10feb7b6c5618df18 166 Gene3D G3DSA:3.40.630.30 1 166 4.0E-27 T 29-03-2018 CSW12_RS13005 95c1578fc95601c10feb7b6c5618df18 166 Pfam PF13420 Acetyltransferase (GNAT) domain 2 158 2.3E-23 T 29-03-2018 CSW12_RS13005 95c1578fc95601c10feb7b6c5618df18 166 SUPERFAMILY SSF55729 1 164 1.66E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS26990 e70e546b5fbd0ef1a3e06912300b6109 432 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS26990 e70e546b5fbd0ef1a3e06912300b6109 432 Pfam PF07690 Major Facilitator Superfamily 27 298 4.9E-42 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS26990 e70e546b5fbd0ef1a3e06912300b6109 432 Gene3D G3DSA:1.20.1250.20 222 432 1.5E-30 T 29-03-2018 CSW12_RS26990 e70e546b5fbd0ef1a3e06912300b6109 432 Gene3D G3DSA:1.20.1250.20 9 210 2.1E-39 T 29-03-2018 CSW12_RS26990 e70e546b5fbd0ef1a3e06912300b6109 432 SUPERFAMILY SSF103473 13 430 5.23E-87 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS00185 1d7da492c27103e550ca45a4c5dab0e1 62 SUPERFAMILY SSF47413 3 61 2.31E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS00185 1d7da492c27103e550ca45a4c5dab0e1 62 SMART SM00530 4 59 2.6E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS00185 1d7da492c27103e550ca45a4c5dab0e1 62 Pfam PF01381 Helix-turn-helix 6 59 3.7E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS00185 1d7da492c27103e550ca45a4c5dab0e1 62 Gene3D G3DSA:1.10.260.40 1 62 2.1E-12 T 29-03-2018 CSW12_RS21405 11792e62d04034c2f1ba3bdaaeb235b8 412 SUPERFAMILY SSF82171 44 389 6.93E-27 T 29-03-2018 CSW12_RS21405 11792e62d04034c2f1ba3bdaaeb235b8 412 Pfam PF08662 Eukaryotic translation initiation factor eIF2A 43 155 6.4E-7 T 29-03-2018 IPR013979 Translation initiation factor, beta propellor-like domain CSW12_RS21405 11792e62d04034c2f1ba3bdaaeb235b8 412 Gene3D G3DSA:2.130.10.150 19 167 2.2E-14 T 29-03-2018 CSW12_RS21405 11792e62d04034c2f1ba3bdaaeb235b8 412 Gene3D G3DSA:2.120.10.60 189 406 2.2E-9 T 29-03-2018 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 SMART SM00926 46 108 2.4E-7 T 29-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 767 784 - T 29-03-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Gene3D G3DSA:3.40.50.740 637 930 1.1E-36 T 29-03-2018 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 51 69 - T 29-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Gene3D G3DSA:3.40.228.10 228 636 2.5E-93 T 29-03-2018 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 6 1226 0.0 T 29-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Pfam PF01568 Molydopterin dinucleotide binding domain 1079 1192 8.8E-23 T 29-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 SUPERFAMILY SSF50692 1070 1225 5.42E-48 T 29-03-2018 IPR009010 Aspartate decarboxylase-like domain CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Gene3D G3DSA:2.40.40.20 1041 1227 3.1E-44 T 29-03-2018 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Gene3D G3DSA:2.20.25.90 58 101 2.0E-25 T 29-03-2018 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 8 43 1.7E-10 T 29-03-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.99.4 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 Pfam PF00384 Molybdopterin oxidoreductase 111 823 8.7E-174 T 29-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS17290 ef4dca5ff410ef5a3c01ad367b4d0834 1227 SUPERFAMILY SSF53706 10 1063 0.0 T 29-03-2018 CSW12_RS30190 25e1e762f269287f7dc45876cad24070 408 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 6 403 5.2E-157 T 29-03-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0042710 CSW12_RS30190 25e1e762f269287f7dc45876cad24070 408 Gene3D G3DSA:3.90.550.10 32 304 3.3E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS30190 25e1e762f269287f7dc45876cad24070 408 SUPERFAMILY SSF53448 40 314 1.53E-63 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS30190 25e1e762f269287f7dc45876cad24070 408 ProDom PD339107 ALGINATE ALG8 BIOSYNTHESIS TRANSFERASE TRANSMEMBRANE MEMBRANE 2.4.1.- GLYCOSYL GLYCOSYLTRANSFERASE PRECURSOR 27 250 4.0E-8 T 29-03-2018 CSW12_RS30190 25e1e762f269287f7dc45876cad24070 408 Pfam PF13641 Glycosyltransferase like family 2 43 268 1.6E-39 T 29-03-2018 CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 365 393 - T 29-03-2018 IPR001587 Ribonuclease J, conserved site CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 SUPERFAMILY SSF56281 10 424 5.66E-98 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 554 4.1E-214 T 29-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 363 409 2.6E-11 T 29-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 Gene3D G3DSA:3.60.15.10 1 449 3.7E-64 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 SMART SM00849 21 216 7.9E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 Hamap MF_01491 Ribonuclease J [rnj]. 4 556 48.406 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.1E-14 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08790 f996df28b480b6f2214d0a5064d97bf6 556 PIRSF PIRSF004803 1 556 5.3E-244 T 29-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CSW12_RS19750 7aa978dfd0b126686c2ff0b655eb2b72 440 TIGRFAM TIGR03173 pbuX: xanthine permease 11 417 1.5E-167 T 29-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CSW12_RS19750 7aa978dfd0b126686c2ff0b655eb2b72 440 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 415 3.7E-138 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CSW12_RS19750 7aa978dfd0b126686c2ff0b655eb2b72 440 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 332 352 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CSW12_RS19750 7aa978dfd0b126686c2ff0b655eb2b72 440 Pfam PF00860 Permease family 7 385 2.7E-114 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS26040 547e26a9054eee87b5b625e4a029c2c1 397 Pfam PF13533 Biotin-lipoyl like 82 119 1.2E-7 T 29-03-2018 CSW12_RS26040 547e26a9054eee87b5b625e4a029c2c1 397 Gene3D G3DSA:2.70.70.10 188 263 0.21 T 29-03-2018 CSW12_RS26040 547e26a9054eee87b5b625e4a029c2c1 397 Pfam PF13437 HlyD family secretion protein 195 309 2.5E-6 T 29-03-2018 CSW12_RS26040 547e26a9054eee87b5b625e4a029c2c1 397 Gene3D G3DSA:2.40.50.100 79 187 1.6E-8 T 29-03-2018 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 1.2E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 1.2E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 127 135 1.2E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 1.2E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 PRINTS PR01703 Manganese superoxide dismutase signature 74 87 1.2E-27 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 91 5.6E-33 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 Gene3D G3DSA:1.10.287.990 21 91 8.9E-32 T 29-03-2018 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 PIRSF PIRSF000349 1 203 5.3E-86 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 198 6.1E-42 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 SUPERFAMILY SSF46609 2 92 4.45E-38 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS20985 22a054e16c44615fbab98b5100c816fe 203 SUPERFAMILY SSF54719 90 201 1.7E-47 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS31045 94d1a71aae7d1044f97d477bbb809ade 332 Gene3D G3DSA:3.90.580.10 1 84 1.3E-8 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CSW12_RS31045 94d1a71aae7d1044f97d477bbb809ade 332 Gene3D G3DSA:3.40.1360.10 191 316 7.9E-21 T 29-03-2018 CSW12_RS31045 94d1a71aae7d1044f97d477bbb809ade 332 SUPERFAMILY SSF57783 7 82 2.55E-6 T 29-03-2018 CSW12_RS31045 94d1a71aae7d1044f97d477bbb809ade 332 Pfam PF13154 Protein of unknown function (DUF3991) 120 189 2.0E-11 T 29-03-2018 IPR025054 Domain of unknown function DUF3991 CSW12_RS31045 94d1a71aae7d1044f97d477bbb809ade 332 Pfam PF13155 Toprim-like 206 298 1.6E-17 T 29-03-2018 CSW12_RS24905 629e6ab6190bf3cc0f3f90e1c829bf02 297 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 238 292 8.4E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS24905 629e6ab6190bf3cc0f3f90e1c829bf02 297 PIRSF PIRSF006483 13 297 1.6E-98 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS24905 629e6ab6190bf3cc0f3f90e1c829bf02 297 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 32 232 1.9E-59 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 PIRSF PIRSF001123 4 361 3.7E-150 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 7.7E-118 T 29-03-2018 IPR008007 Peptidase M42 CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 Gene3D G3DSA:2.40.30.40 72 163 1.6E-35 T 29-03-2018 IPR023367 Peptidase M42, domain 2 CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 SUPERFAMILY SSF101821 73 182 2.9E-34 T 29-03-2018 CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 Gene3D G3DSA:3.40.630.10 168 359 1.0E-45 T 29-03-2018 CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 SUPERFAMILY SSF53187 174 355 2.62E-71 T 29-03-2018 CSW12_RS22470 7e6a8969768d1de0b90aae5c1dfdf620 361 SUPERFAMILY SSF53187 8 83 2.62E-71 T 29-03-2018 CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 Gene3D G3DSA:1.20.1560.10 1 327 6.8E-70 T 29-03-2018 CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 Pfam PF00005 ABC transporter 358 507 1.0E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 SUPERFAMILY SSF90123 5 324 2.22E-78 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 SUPERFAMILY SSF52540 331 578 1.7E-95 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 SMART SM00382 367 553 8.3E-18 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 Pfam PF00664 ABC transporter transmembrane region 20 294 1.1E-39 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS01240 077fd7188ad79894baa54ff22ff9e523 586 Gene3D G3DSA:3.40.50.300 328 583 8.2E-78 T 29-03-2018 CSW12_RS26130 8ef876f3e4c453d6f73b930584eebb94 405 Gene3D G3DSA:3.40.640.10 1 270 7.4E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS26130 8ef876f3e4c453d6f73b930584eebb94 405 Gene3D G3DSA:3.90.1150.10 271 405 1.9E-32 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS26130 8ef876f3e4c453d6f73b930584eebb94 405 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 398 1.4E-88 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CSW12_RS26130 8ef876f3e4c453d6f73b930584eebb94 405 SUPERFAMILY SSF53383 8 404 9.57E-98 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS26130 8ef876f3e4c453d6f73b930584eebb94 405 PIRSF PIRSF000390 5 405 1.9E-83 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CSW12_RS19465 b4ad58bf69a054376eadf1415346427e 155 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 124 2.4E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS19465 b4ad58bf69a054376eadf1415346427e 155 Gene3D G3DSA:3.10.180.10 1 155 5.3E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS19465 b4ad58bf69a054376eadf1415346427e 155 SUPERFAMILY SSF54593 1 129 4.4E-22 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12655 805ad6888be48a67aa02dfa9e65d30e4 192 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 3 158 2.2E-7 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS12655 805ad6888be48a67aa02dfa9e65d30e4 192 SUPERFAMILY SSF56784 3 185 1.76E-27 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS12655 805ad6888be48a67aa02dfa9e65d30e4 192 Gene3D G3DSA:3.40.50.1000 61 191 1.2E-13 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS12655 805ad6888be48a67aa02dfa9e65d30e4 192 Gene3D G3DSA:1.10.150.240 13 60 8.8E-8 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS12655 805ad6888be48a67aa02dfa9e65d30e4 192 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 163 5.3E-18 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16980 0ce3bcb434bf7ef09a61ba795723a454 239 Gene3D G3DSA:2.160.10.20 167 231 2.5E-16 T 29-03-2018 CSW12_RS16980 0ce3bcb434bf7ef09a61ba795723a454 239 Gene3D G3DSA:2.160.20.80 1 166 2.0E-25 T 29-03-2018 CSW12_RS16980 0ce3bcb434bf7ef09a61ba795723a454 239 SUPERFAMILY SSF141571 26 146 8.37E-19 T 29-03-2018 CSW12_RS16980 0ce3bcb434bf7ef09a61ba795723a454 239 Pfam PF00805 Pentapeptide repeats (8 copies) 170 209 8.8E-11 T 29-03-2018 IPR001646 Pentapeptide repeat CSW12_RS16980 0ce3bcb434bf7ef09a61ba795723a454 239 SUPERFAMILY SSF141571 115 230 8.24E-28 T 29-03-2018 CSW12_RS16980 0ce3bcb434bf7ef09a61ba795723a454 239 Pfam PF13599 Pentapeptide repeats (9 copies) 67 144 5.4E-7 T 29-03-2018 IPR001646 Pentapeptide repeat CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 SUPERFAMILY SSF54197 6 140 2.78E-47 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 ProSitePatterns PS00892 HIT domain signature. 90 108 - T 29-03-2018 IPR019808 Histidine triad, conserved site CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 Pfam PF01230 HIT domain 16 110 9.0E-28 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 Gene3D G3DSA:1.20.5.1170 125 143 3.5E-13 T 29-03-2018 CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 PRINTS PR00332 Histidine triad family signature 97 107 1.9E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 PRINTS PR00332 Histidine triad family signature 30 48 1.9E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 PRINTS PR00332 Histidine triad family signature 9 25 1.9E-17 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS04535 b25abbc5738d1d156976426497900c59 144 Gene3D G3DSA:3.30.428.10 6 124 1.2E-36 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS20520 59363e281c5115b916b3a5ee61b7247d 214 Pfam PF12685 SpoIIIAH-like protein 5 201 3.7E-36 T 29-03-2018 IPR024232 Stage III sporulation protein AH-like CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 Pfam PF01938 TRAM domain 391 427 3.4E-6 T 29-03-2018 IPR002792 TRAM domain CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 7.1E-27 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 Gene3D G3DSA:3.80.30.20 140 375 5.9E-48 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 Pfam PF04055 Radical SAM superfamily 149 319 4.8E-27 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 SUPERFAMILY SSF102114 119 365 4.19E-56 T 29-03-2018 CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 2.5E-140 T 29-03-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 429 9.1E-149 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 SMART SM00729 143 361 9.1E-58 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS21170 12d1c07f471ae52299f4e1a210d481f9 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CSW12_RS05680 d6f9a3645b5e9571392c69ca9d0af30f 243 Pfam PF00756 Putative esterase 15 238 6.0E-49 T 29-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CSW12_RS05680 d6f9a3645b5e9571392c69ca9d0af30f 243 Gene3D G3DSA:3.40.50.1820 1 243 1.3E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS05680 d6f9a3645b5e9571392c69ca9d0af30f 243 SUPERFAMILY SSF53474 4 239 9.09E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 233 1.2E-40 T 29-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 SUPERFAMILY SSF54292 2 111 3.13E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 Pfam PF13183 4Fe-4S dicluster domain 150 225 4.2E-9 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 154 165 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 SUPERFAMILY SSF46548 113 238 2.44E-26 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 Gene3D G3DSA:3.10.20.30 1 110 7.4E-24 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 Gene3D G3DSA:1.10.1060.10 111 243 4.4E-17 T 29-03-2018 CSW12_RS22175 f1adeede25b2b3a2ef9baec68f200b34 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 117 8.7E-29 T 29-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 SUPERFAMILY SSF53807 15 314 1.47E-86 T 29-03-2018 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 Gene3D G3DSA:3.40.50.1980 196 315 3.7E-35 T 29-03-2018 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00691 Adhesin B signature 145 164 1.6E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00691 Adhesin B signature 294 312 1.6E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00691 Adhesin B signature 34 55 1.6E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00691 Adhesin B signature 59 77 1.6E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00691 Adhesin B signature 201 218 1.6E-11 T 29-03-2018 IPR006129 Adhesin B GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 Gene3D G3DSA:3.40.50.1980 23 195 9.0E-59 T 29-03-2018 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 314 3.3E-79 T 29-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00690 Adhesin family signature 65 78 4.5E-11 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00690 Adhesin family signature 78 95 4.5E-11 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00690 Adhesin family signature 34 52 4.5E-11 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CSW12_RS17740 ca9e75b47bc7bb4e2af0d28f9c30d3d3 316 PRINTS PR00690 Adhesin family signature 201 222 4.5E-11 T 29-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 2067 2162 1.9E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 743 836 1.3E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1405 1499 1.3E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 478 564 1.5E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1935 2028 1.7E-11 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1671 1766 2.2E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1269 1366 4.2E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 610 704 9.3E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1138 1232 1.5E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 873 963 4.6E-8 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 346 437 1.0E-13 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 2331 2428 8.3E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1006 1096 1.7E-10 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Pfam PF01345 Domain of unknown function DUF11 1803 1898 4.8E-11 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1935 1987 8.1E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2333 2384 3.4E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1271 1322 6.2E-15 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1007 1058 9.3E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2067 2119 2.7E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2199 2250 5.0E-14 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 875 927 2.3E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 743 795 4.2E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1803 1854 3.8E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 611 663 1.3E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 347 399 2.6E-18 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1539 1591 1.2E-16 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1671 1723 8.8E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1139 1191 3.0E-19 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 479 531 9.3E-20 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1406 1458 3.0E-17 T 29-03-2018 IPR001434 Domain of unknown function DUF11 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 344 474 3.5E-21 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 2194 2323 1.5E-10 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.10 1665 1793 2.8E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 2325 2453 1.2E-17 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1927 2060 1.2E-18 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1539 1663 4.4E-13 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1794 1926 1.7E-18 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1132 1264 1.7E-20 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1400 1531 3.6E-19 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 869 999 3.6E-17 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 2061 2193 2.4E-17 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 605 737 1.2E-18 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 738 868 3.8E-19 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 475 604 5.6E-19 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1000 1130 5.8E-20 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 Gene3D G3DSA:2.60.40.740 1265 1395 2.2E-19 T 29-03-2018 CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 SUPERFAMILY SSF49401 355 447 1.54E-5 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS10030 a7f684bfc03f59cafd68130372efc0a1 2490 SUPERFAMILY SSF49401 486 579 1.32E-5 T 29-03-2018 IPR008966 Adhesion domain CSW12_RS24620 29ab6be3fc59b3cb288b70ac04c8baa6 88 Pfam PF11256 Protein of unknown function (DUF3055) 7 85 3.9E-36 T 29-03-2018 IPR021415 Protein of unknown function DUF3055 CSW12_RS08120 7be25a4b5463529b6703b977f2e70809 345 SMART SM00228 120 187 0.0038 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS08120 7be25a4b5463529b6703b977f2e70809 345 SUPERFAMILY SSF54211 229 334 7.21E-23 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS08120 7be25a4b5463529b6703b977f2e70809 345 Gene3D G3DSA:3.30.230.10 39 345 4.9E-42 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS08120 7be25a4b5463529b6703b977f2e70809 345 Pfam PF13180 PDZ domain 127 194 1.9E-13 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS08120 7be25a4b5463529b6703b977f2e70809 345 SUPERFAMILY SSF50156 128 214 1.71E-15 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS08120 7be25a4b5463529b6703b977f2e70809 345 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 233 331 1.8E-11 T 29-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CSW12_RS23800 5765e4488c8f4a84d73dcbb87bdde8b9 206 Gene3D G3DSA:2.40.260.10 23 206 3.5E-32 T 29-03-2018 IPR023365 Sortase domain CSW12_RS23800 5765e4488c8f4a84d73dcbb87bdde8b9 206 TIGRFAM TIGR01076 sortase_fam: sortase 77 197 1.6E-22 T 29-03-2018 IPR005754 Sortase family CSW12_RS23800 5765e4488c8f4a84d73dcbb87bdde8b9 206 Pfam PF04203 Sortase family 78 200 1.4E-26 T 29-03-2018 IPR005754 Sortase family CSW12_RS23800 5765e4488c8f4a84d73dcbb87bdde8b9 206 SUPERFAMILY SSF63817 72 201 9.94E-34 T 29-03-2018 IPR023365 Sortase domain CSW12_RS04205 742bd2bddea735f39d1b2aafba606780 369 SUPERFAMILY SSF48452 94 130 1.01E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04205 742bd2bddea735f39d1b2aafba606780 369 SUPERFAMILY SSF48452 166 270 1.01E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04205 742bd2bddea735f39d1b2aafba606780 369 Gene3D G3DSA:1.25.40.10 156 366 2.9E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04205 742bd2bddea735f39d1b2aafba606780 369 Gene3D G3DSA:1.25.40.10 2 148 4.8E-24 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS26085 accdf231fdc7e84c3e8028a47aac71da 276 PIRSF PIRSF030175 2 276 5.8E-111 T 29-03-2018 IPR016948 Uncharacterised conserved protein UCP030175 CSW12_RS26085 accdf231fdc7e84c3e8028a47aac71da 276 SUPERFAMILY SSF52266 105 273 7.99E-10 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS26085 accdf231fdc7e84c3e8028a47aac71da 276 Gene3D G3DSA:3.40.50.1110 40 273 3.6E-14 T 29-03-2018 CSW12_RS03400 a18656cb0eeb23e5649ee75c454fd1bb 201 Pfam PF09335 SNARE associated Golgi protein 29 154 2.2E-23 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 Gene3D G3DSA:3.40.50.300 25 223 2.4E-27 T 29-03-2018 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 48 309 1.1E-134 T 29-03-2018 IPR014232 Sporulation stage V, protein K CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 194 211 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 91 106 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 143 162 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 271 283 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 211 230 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 129 143 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 173 185 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 PRINTS PR00819 CbxX/CfqX superfamily signature 51 65 1.6E-58 T 29-03-2018 IPR000641 CbxX/CfqX GO:0005524 CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 SUPERFAMILY SSF52540 53 300 8.9E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 SMART SM00382 88 226 3.8E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS09250 923d8c9bcd3e67db950db9e0dafd07bc 318 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 92 222 1.0E-19 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS27995 e4f8ed7e0459f9ad9bdf9874e879add0 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 20.572 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CSW12_RS27995 e4f8ed7e0459f9ad9bdf9874e879add0 96 Gene3D G3DSA:3.30.70.330 2 96 4.6E-31 T 29-03-2018 CSW12_RS27995 e4f8ed7e0459f9ad9bdf9874e879add0 96 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 29-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27995 e4f8ed7e0459f9ad9bdf9874e879add0 96 SUPERFAMILY SSF54189 1 91 1.73E-30 T 29-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27995 e4f8ed7e0459f9ad9bdf9874e879add0 96 Pfam PF00276 Ribosomal protein L23 6 88 3.9E-31 T 29-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 SUPERFAMILY SSF52304 3 144 7.72E-59 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 142 4.0E-65 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 29-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 Pfam PF01220 Dehydroquinase class II 3 139 1.8E-61 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 Gene3D G3DSA:3.40.50.9100 1 146 1.4E-64 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 PIRSF PIRSF001399 1 146 8.0E-63 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 65.985 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS20585 58f996f7f3b834b01d1ddb671160914a 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 141 2.0E-65 T 29-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 SUPERFAMILY SSF56801 5 531 6.02E-139 T 29-03-2018 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 1.0E-13 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 Gene3D G3DSA:3.40.50.980 180 352 1.3E-32 T 29-03-2018 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 Pfam PF00501 AMP-binding enzyme 32 435 5.1E-86 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 4 526 3.0E-249 T 29-03-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 Gene3D G3DSA:3.40.50.980 22 179 2.2E-33 T 29-03-2018 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 Gene3D G3DSA:3.30.300.30 430 537 2.7E-23 T 29-03-2018 CSW12_RS16180 574f76b9b6ce2f503f3d9f3389c6c9ab 538 Gene3D G3DSA:2.30.38.10 354 429 6.1E-21 T 29-03-2018 CSW12_RS24765 8c67a58ca5b30ea564013420b49ae10f 127 SUPERFAMILY SSF51230 3 125 2.36E-46 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS24765 8c67a58ca5b30ea564013420b49ae10f 127 Pfam PF01597 Glycine cleavage H-protein 7 126 2.1E-49 T 29-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CSW12_RS24765 8c67a58ca5b30ea564013420b49ae10f 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.698 T 29-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CSW12_RS24765 8c67a58ca5b30ea564013420b49ae10f 127 Gene3D G3DSA:2.40.50.100 5 127 1.5E-49 T 29-03-2018 CSW12_RS24765 8c67a58ca5b30ea564013420b49ae10f 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CSW12_RS24765 8c67a58ca5b30ea564013420b49ae10f 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 9.7E-58 T 29-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CSW12_RS23145 b31e32c5f6b1a3bf5e5fd428f40af2fb 270 Hamap MF_01548 UPF0354 protein . 3 264 48.366 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CSW12_RS23145 b31e32c5f6b1a3bf5e5fd428f40af2fb 270 PIRSF PIRSF012562 1 264 3.1E-138 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CSW12_RS23145 b31e32c5f6b1a3bf5e5fd428f40af2fb 270 Pfam PF07285 Protein of unknown function (DUF1444) 3 263 9.1E-122 T 29-03-2018 IPR010838 Protein of unknown unction DUF1444 CSW12_RS20620 399481a1788d64a7ce7002f32c630ebb 105 SUPERFAMILY SSF46785 3 91 1.04E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20620 399481a1788d64a7ce7002f32c630ebb 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 2.9E-21 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS20620 399481a1788d64a7ce7002f32c630ebb 105 Gene3D G3DSA:1.10.10.10 1 97 2.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02620 2d6dc75cb9c6eca4f9e032589501b848 426 Pfam PF06725 3D domain 367 426 3.5E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CSW12_RS02620 2d6dc75cb9c6eca4f9e032589501b848 426 SUPERFAMILY SSF50685 366 406 2.16E-7 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS02620 2d6dc75cb9c6eca4f9e032589501b848 426 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 45 242 8.0E-4 T 29-03-2018 CSW12_RS02620 2d6dc75cb9c6eca4f9e032589501b848 426 Gene3D G3DSA:1.20.5.170 25 126 4.4E-5 T 29-03-2018 CSW12_RS02620 2d6dc75cb9c6eca4f9e032589501b848 426 Gene3D G3DSA:2.40.40.10 206 425 3.8E-38 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS18240 f8cbf4048c87948a44a92967c5b5deda 536 Gene3D G3DSA:3.90.1300.10 61 536 6.3E-112 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS18240 f8cbf4048c87948a44a92967c5b5deda 536 SUPERFAMILY SSF75304 67 533 2.49E-95 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS18240 f8cbf4048c87948a44a92967c5b5deda 536 Pfam PF01425 Amidase 89 517 3.7E-76 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS15985 2771ede73d0d9e2b5c85e85b9f3dc87f 306 SUPERFAMILY SSF141571 166 295 2.22E-21 T 29-03-2018 CSW12_RS15985 2771ede73d0d9e2b5c85e85b9f3dc87f 306 SUPERFAMILY SSF55729 1 149 5.4E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS15985 2771ede73d0d9e2b5c85e85b9f3dc87f 306 Gene3D G3DSA:3.40.630.30 1 165 1.8E-31 T 29-03-2018 CSW12_RS15985 2771ede73d0d9e2b5c85e85b9f3dc87f 306 Gene3D G3DSA:2.160.10.20 166 292 1.8E-19 T 29-03-2018 CSW12_RS15985 2771ede73d0d9e2b5c85e85b9f3dc87f 306 Pfam PF13673 Acetyltransferase (GNAT) domain 62 147 3.5E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS15985 2771ede73d0d9e2b5c85e85b9f3dc87f 306 Pfam PF13599 Pentapeptide repeats (9 copies) 169 245 2.3E-17 T 29-03-2018 IPR001646 Pentapeptide repeat CSW12_RS22215 910b7ad39542480a68ea1813bc56f841 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CSW12_RS22215 910b7ad39542480a68ea1813bc56f841 258 SUPERFAMILY SSF52096 2 258 3.58E-83 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS22215 910b7ad39542480a68ea1813bc56f841 258 Gene3D G3DSA:1.10.12.10 216 258 9.1E-17 T 29-03-2018 IPR014748 Crontonase, C-terminal CSW12_RS22215 910b7ad39542480a68ea1813bc56f841 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 5.1E-65 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CSW12_RS22215 910b7ad39542480a68ea1813bc56f841 258 Gene3D G3DSA:3.90.226.10 5 215 2.0E-70 T 29-03-2018 CSW12_RS16690 3527d5cb2db103146300b343bb05b00a 393 Gene3D G3DSA:1.20.1170.10 32 392 7.9E-4 T 29-03-2018 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 ProSitePatterns PS01053 Arginase family signature. 222 243 - T 29-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 Gene3D G3DSA:3.40.800.10 1 293 2.7E-94 T 29-03-2018 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 PRINTS PR00116 Arginase signature 254 268 1.9E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 PRINTS PR00116 Arginase signature 117 144 1.9E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 PRINTS PR00116 Arginase signature 94 109 1.9E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 PRINTS PR00116 Arginase signature 219 248 1.9E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 PRINTS PR00116 Arginase signature 171 189 1.9E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 SUPERFAMILY SSF52768 4 293 8.82E-93 T 29-03-2018 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 PIRSF PIRSF036979 1 294 3.4E-40 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 Pfam PF00491 Arginase family 4 292 4.8E-80 T 29-03-2018 IPR006035 Ureohydrolase GO:0046872 CSW12_RS28265 f841ebe4c96b3cd73d2fa8c203866f25 297 TIGRFAM TIGR01229 rocF_arginase: arginase 6 296 5.6E-106 T 29-03-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 ProSitePatterns PS00217 Sugar transport proteins signature 2. 323 348 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 86 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 Pfam PF07690 Major Facilitator Superfamily 25 282 7.9E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 Pfam PF07690 Major Facilitator Superfamily 291 410 1.0E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 Gene3D G3DSA:1.20.1250.20 212 416 3.5E-25 T 29-03-2018 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 SUPERFAMILY SSF103473 16 404 1.7E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 PRINTS PR01035 Tetracycline resistance protein signature 290 311 1.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 PRINTS PR01035 Tetracycline resistance protein signature 26 42 1.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 PRINTS PR01035 Tetracycline resistance protein signature 147 169 1.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 PRINTS PR01035 Tetracycline resistance protein signature 175 195 1.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 PRINTS PR01035 Tetracycline resistance protein signature 347 370 1.3E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17920 e25e3b966a0d21cf90fd0e0f932cbc44 417 Gene3D G3DSA:1.20.1250.20 8 204 2.2E-37 T 29-03-2018 CSW12_RS21505 3c3c49d3cf8e05ffffa8bd0134921321 231 SUPERFAMILY SSF53167 2 230 3.4E-71 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS21505 3c3c49d3cf8e05ffffa8bd0134921321 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 46.549 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS21505 3c3c49d3cf8e05ffffa8bd0134921321 231 Pfam PF01048 Phosphorylase superfamily 2 227 1.8E-52 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS21505 3c3c49d3cf8e05ffffa8bd0134921321 231 Gene3D G3DSA:3.40.50.1580 1 231 4.4E-56 T 29-03-2018 CSW12_RS21505 3c3c49d3cf8e05ffffa8bd0134921321 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 6.3E-116 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 SUPERFAMILY SSF51161 1 185 1.8E-53 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 Pfam PF12464 Maltose acetyltransferase 7 56 2.3E-14 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 SMART SM01266 5 59 2.3E-18 T 29-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 140 168 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 Gene3D G3DSA:2.160.10.10 2 187 1.1E-52 T 29-03-2018 CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 131 166 1.4E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS11190 2b563e549aaf1d0365e6bec0a6a9d265 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 87 111 0.16 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Gene3D G3DSA:3.40.50.620 14 366 8.9E-107 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Pfam PF09334 tRNA synthetases class I (M) 17 382 3.1E-121 T 29-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Pfam PF01588 Putative tRNA binding domain 575 667 2.9E-27 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Gene3D G3DSA:2.40.50.140 561 669 2.3E-30 T 29-03-2018 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 539 669 5.7E-48 T 29-03-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Gene3D G3DSA:1.10.730.10 367 534 1.7E-41 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Pfam PF08264 Anticodon-binding domain of tRNA 405 508 3.2E-8 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 Hamap MF_01228 Methionine--tRNA ligase [metG]. 10 531 51.153 T 29-03-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 SUPERFAMILY SSF50249 563 668 7.83E-33 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 19 32 9.2E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 51 65 9.2E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 99 110 9.2E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 245 256 9.2E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 370 381 9.2E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 PRINTS PR01041 Methionyl-tRNA synthetase signature 278 293 9.2E-34 T 29-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 17 532 1.3E-179 T 29-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 SUPERFAMILY SSF47323 372 582 3.76E-47 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 26 35 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27535 72242e63dc5ae665cb7e6439b7067258 669 SUPERFAMILY SSF52374 14 373 1.34E-118 T 29-03-2018 CSW12_RS12430 7ac5c8bc2a74592058b22401e7043849 309 SUPERFAMILY SSF56112 16 260 2.65E-41 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS12430 7ac5c8bc2a74592058b22401e7043849 309 Gene3D G3DSA:3.90.1200.10 89 263 1.0E-15 T 29-03-2018 CSW12_RS12430 7ac5c8bc2a74592058b22401e7043849 309 Gene3D G3DSA:3.30.200.20 2 88 5.4E-5 T 29-03-2018 CSW12_RS12430 7ac5c8bc2a74592058b22401e7043849 309 Pfam PF01636 Phosphotransferase enzyme family 20 249 6.5E-31 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS18780 96f91b7a8ee99478e92a1c93d69f1ef1 327 Pfam PF03590 Aspartate-ammonia ligase 12 237 1.6E-106 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CSW12_RS18780 96f91b7a8ee99478e92a1c93d69f1ef1 327 SUPERFAMILY SSF55681 8 320 1.9E-87 T 29-03-2018 CSW12_RS18780 96f91b7a8ee99478e92a1c93d69f1ef1 327 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 4 323 50.397 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CSW12_RS18780 96f91b7a8ee99478e92a1c93d69f1ef1 327 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 12 318 7.4E-103 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CSW12_RS18780 96f91b7a8ee99478e92a1c93d69f1ef1 327 Gene3D G3DSA:3.30.930.10 1 322 8.6E-38 T 29-03-2018 CSW12_RS18780 96f91b7a8ee99478e92a1c93d69f1ef1 327 PIRSF PIRSF001555 1 327 9.4E-162 T 29-03-2018 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1 CSW12_RS18235 45145a3564404453972fe5361a3423d2 337 Pfam PF01594 AI-2E family transporter 16 328 1.4E-44 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 187 345 9.7E-33 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 SUPERFAMILY SSF53756 2 349 1.38E-95 T 29-03-2018 CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 350 29.036 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 349 1.7E-84 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 141 5.4E-39 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 Gene3D G3DSA:3.40.50.2000 1 175 5.7E-37 T 29-03-2018 CSW12_RS20875 9736eef9db7585e687ba28055818d049 352 Gene3D G3DSA:3.40.50.2000 176 337 3.5E-27 T 29-03-2018 CSW12_RS24510 f0ce36312e7b7fc99c39690eb25eb988 265 Pfam PF03649 Uncharacterised protein family (UPF0014) 10 251 4.5E-84 T 29-03-2018 IPR005226 UPF0014 family CSW12_RS24510 f0ce36312e7b7fc99c39690eb25eb988 265 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 9 257 5.3E-56 T 29-03-2018 IPR005226 UPF0014 family CSW12_RS21700 3306941f7275552f65699a70e4bda4c4 94 Pfam PF13797 Post-transcriptional regulator 8 90 2.2E-31 T 29-03-2018 IPR025716 Post-transcriptional regulator CSW12_RS01415 95638c51094f859584313533b866888c 216 Pfam PF13462 Thioredoxin 44 212 8.5E-36 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS01415 95638c51094f859584313533b866888c 216 Gene3D G3DSA:3.40.30.10 43 216 4.6E-36 T 29-03-2018 CSW12_RS01415 95638c51094f859584313533b866888c 216 SUPERFAMILY SSF52833 41 211 8.17E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS06480 944afecf9cbcc637b59507adbadb8e2f 409 Pfam PF01610 Transposase 293 397 2.9E-13 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS06480 944afecf9cbcc637b59507adbadb8e2f 409 Pfam PF01610 Transposase 2 200 1.4E-11 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS06480 944afecf9cbcc637b59507adbadb8e2f 409 Pfam PF08279 HTH domain 161 199 1.5E-4 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS06480 944afecf9cbcc637b59507adbadb8e2f 409 Gene3D G3DSA:1.10.10.60 90 138 1.9E-4 T 29-03-2018 CSW12_RS06480 944afecf9cbcc637b59507adbadb8e2f 409 Gene3D G3DSA:1.10.10.60 149 186 1.5E-9 T 29-03-2018 CSW12_RS06480 944afecf9cbcc637b59507adbadb8e2f 409 Gene3D G3DSA:1.10.1660.10 187 267 0.024 T 29-03-2018 CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 2.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 2.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 2.5E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 SMART SM00347 31 132 1.6E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 Pfam PF01047 MarR family 40 97 6.1E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 SUPERFAMILY SSF46785 11 147 2.66E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15300 6067f6af7722af3354ea722c20d57eba 149 Gene3D G3DSA:1.10.10.10 1 149 9.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 7.6E-127 T 29-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 2.0E-134 T 29-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 Gene3D G3DSA:3.40.50.1100 140 305 1.4E-55 T 29-03-2018 CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 5.6E-68 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 SUPERFAMILY SSF53686 2 303 1.26E-99 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18695 9bc82cb0d9721ed21f3e865faecb3594 305 Gene3D G3DSA:3.40.50.1100 42 139 2.1E-37 T 29-03-2018 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 SUPERFAMILY SSF48498 87 206 4.97E-27 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.7E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 Gene3D G3DSA:1.10.10.60 9 67 4.2E-14 T 29-03-2018 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.4E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 Gene3D G3DSA:1.10.357.10 68 211 3.7E-9 T 29-03-2018 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 SUPERFAMILY SSF46689 11 72 1.13E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS10175 9568fa143df23468a1f5477d8dfe84b1 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS12280 17b904f4c6a840cfe2f655faef86e9c8 225 Gene3D G3DSA:3.20.20.380 1 225 2.1E-71 T 29-03-2018 CSW12_RS12280 17b904f4c6a840cfe2f655faef86e9c8 225 Pfam PF03932 CutC family 2 199 7.4E-56 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CSW12_RS12280 17b904f4c6a840cfe2f655faef86e9c8 225 SUPERFAMILY SSF110395 1 224 2.88E-60 T 29-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 1.5E-51 T 29-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 Gene3D G3DSA:3.30.70.250 138 189 1.1E-19 T 29-03-2018 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 SUPERFAMILY SSF52151 190 307 4.19E-80 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 SUPERFAMILY SSF52151 4 121 4.19E-80 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 Gene3D G3DSA:3.40.366.10 190 313 7.7E-29 T 29-03-2018 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 Gene3D G3DSA:3.40.366.10 3 137 9.4E-44 T 29-03-2018 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 Pfam PF00698 Acyl transferase domain 6 282 1.8E-41 T 29-03-2018 IPR014043 Acyl transferase CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 SUPERFAMILY SSF55048 128 193 4.84E-14 T 29-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 PIRSF PIRSF000446 1 311 3.6E-118 T 29-03-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CSW12_RS08515 b3b0731adc863b3588962fd8e1d52787 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 289 1.2E-113 T 29-03-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CSW12_RS15960 2ceedeaaaab62744822da54f10d94b3a 49 Pfam PF09388 Spo0E like sporulation regulatory protein 6 46 1.7E-13 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CSW12_RS15960 2ceedeaaaab62744822da54f10d94b3a 49 SUPERFAMILY SSF140500 1 48 1.7E-14 T 29-03-2018 CSW12_RS24600 a426e0dd2971205148f2510334270868 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 6 105 2.6E-27 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CSW12_RS24600 a426e0dd2971205148f2510334270868 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 2 250 6.5E-125 T 29-03-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 CSW12_RS24600 a426e0dd2971205148f2510334270868 254 PIRSF PIRSF000915 108 253 6.6E-35 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CSW12_RS24600 a426e0dd2971205148f2510334270868 254 PIRSF PIRSF000915 1 113 1.1E-26 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CSW12_RS24600 a426e0dd2971205148f2510334270868 254 Gene3D G3DSA:3.40.50.1000 70 169 3.0E-33 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS24600 a426e0dd2971205148f2510334270868 254 Gene3D G3DSA:3.40.50.1000 170 233 0.12 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS24600 a426e0dd2971205148f2510334270868 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 6 226 4.1E-42 T 29-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CSW12_RS24600 a426e0dd2971205148f2510334270868 254 Pfam PF13242 HAD-hyrolase-like 177 249 1.1E-21 T 29-03-2018 CSW12_RS24600 a426e0dd2971205148f2510334270868 254 SUPERFAMILY SSF56784 1 251 1.68E-76 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 SMART SM00448 2 112 2.2E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 Gene3D G3DSA:3.40.50.2300 2 122 1.0E-40 T 29-03-2018 CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 6.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 SUPERFAMILY SSF52172 1 172 5.41E-44 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 SMART SM00862 143 220 3.4E-21 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 Pfam PF00072 Response regulator receiver domain 4 113 4.5E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01960 91344cb329f5b758e0f7dc2bec343cfe 225 Gene3D G3DSA:1.10.10.10 123 223 4.0E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 Pfam PF00271 Helicase conserved C-terminal domain 897 1008 3.5E-22 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 SMART SM00490 926 1008 1.9E-24 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 Pfam PF00176 SNF2 family N-terminal domain 568 886 3.1E-49 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 SUPERFAMILY SSF52540 592 814 1.84E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 Gene3D G3DSA:3.40.50.10810 614 881 8.1E-43 T 29-03-2018 CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 SMART SM00487 609 795 8.9E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 SUPERFAMILY SSF52540 816 1063 3.33E-68 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 Pfam PF08455 Bacterial SNF2 helicase associated 235 606 3.4E-84 T 29-03-2018 IPR013663 Helicase, SWF/SNF/SWI type, bacterial CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 Gene3D G3DSA:3.40.50.300 888 1046 1.8E-40 T 29-03-2018 CSW12_RS18795 38bb75583949f67bd499df39ec44883a 1064 Pfam PF04434 SWIM zinc finger 53 91 8.8E-5 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CSW12_RS01650 4edc9042b2aa416806addbead2bb4fca 168 Gene3D G3DSA:3.40.630.30 1 168 7.1E-29 T 29-03-2018 CSW12_RS01650 4edc9042b2aa416806addbead2bb4fca 168 SUPERFAMILY SSF55729 1 167 1.99E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS01650 4edc9042b2aa416806addbead2bb4fca 168 Pfam PF13420 Acetyltransferase (GNAT) domain 3 159 6.3E-20 T 29-03-2018 CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 353 58.013 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 Gene3D G3DSA:3.40.640.10 65 272 7.7E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 SUPERFAMILY SSF53383 21 351 4.03E-74 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 Gene3D G3DSA:3.90.1150.10 273 354 1.9E-13 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 Pfam PF00155 Aminotransferase class I and II 31 347 1.4E-50 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CSW12_RS12915 3367ce1db15aae5da7ec81ef12830abb 366 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 351 1.5E-101 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CSW12_RS10655 45675f8c9187037d1179422a4a2a90c1 250 Pfam PF00753 Metallo-beta-lactamase superfamily 33 235 6.2E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10655 45675f8c9187037d1179422a4a2a90c1 250 SMART SM00849 34 235 9.0E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10655 45675f8c9187037d1179422a4a2a90c1 250 Gene3D G3DSA:3.60.15.10 1 241 5.9E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10655 45675f8c9187037d1179422a4a2a90c1 250 SUPERFAMILY SSF56281 24 236 4.46E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS06545 8246ab5d565b923bf6f043f8653e66a9 82 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 4 50 3.0E-20 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CSW12_RS06545 8246ab5d565b923bf6f043f8653e66a9 82 Gene3D G3DSA:3.40.50.880 3 76 1.3E-4 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS06545 8246ab5d565b923bf6f043f8653e66a9 82 Pfam PF03698 Uncharacterised protein family (UPF0180) 6 81 6.7E-30 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CSW12_RS06545 8246ab5d565b923bf6f043f8653e66a9 82 Hamap MF_00506 UPF0180 protein . 4 82 29.039 T 29-03-2018 IPR005370 Uncharacterised protein family UPF0180 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 97 112 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 442 4.5E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 PRINTS PR00175 Sodium/alanine symporter signature 215 234 5.2E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 PRINTS PR00175 Sodium/alanine symporter signature 351 373 5.2E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 PRINTS PR00175 Sodium/alanine symporter signature 187 205 5.2E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 PRINTS PR00175 Sodium/alanine symporter signature 97 119 5.2E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 PRINTS PR00175 Sodium/alanine symporter signature 411 431 5.2E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 PRINTS PR00175 Sodium/alanine symporter signature 306 324 5.2E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25095 0dd7ebed3b86b8fa2f64e8159d54f828 480 Pfam PF01235 Sodium:alanine symporter family 59 454 1.4E-163 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS02615 af14e466e9bcd3a926256ed79c2a8ad6 313 SUPERFAMILY SSF58104 32 300 6.67E-58 T 29-03-2018 CSW12_RS02615 af14e466e9bcd3a926256ed79c2a8ad6 313 SMART SM00283 53 313 1.9E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS02615 af14e466e9bcd3a926256ed79c2a8ad6 313 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 127 280 1.8E-39 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS02615 af14e466e9bcd3a926256ed79c2a8ad6 313 Gene3D G3DSA:1.20.1170.10 3 76 0.005 T 29-03-2018 CSW12_RS02615 af14e466e9bcd3a926256ed79c2a8ad6 313 Gene3D G3DSA:1.10.287.950 77 281 1.3E-43 T 29-03-2018 CSW12_RS01565 e7805e31249cdecbe4505abdbf62ec6d 234 Gene3D G3DSA:3.60.21.10 1 234 5.9E-47 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS01565 e7805e31249cdecbe4505abdbf62ec6d 234 Pfam PF00149 Calcineurin-like phosphoesterase 3 207 1.1E-16 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS01565 e7805e31249cdecbe4505abdbf62ec6d 234 SUPERFAMILY SSF56300 3 216 7.74E-40 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS20535 740b13f6a9e9ade661ae887f8ead4f32 390 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 68 383 3.4E-109 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CSW12_RS20535 740b13f6a9e9ade661ae887f8ead4f32 390 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 2 383 9.7E-162 T 29-03-2018 IPR014194 Sporulation stage III, protein AE CSW12_RS07415 54d1a02d69cf6b93353488b251c8a413 262 Gene3D G3DSA:3.40.50.1360 1 250 9.0E-72 T 29-03-2018 CSW12_RS07415 54d1a02d69cf6b93353488b251c8a413 262 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 232 2.0E-72 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CSW12_RS07415 54d1a02d69cf6b93353488b251c8a413 262 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 234 40.06 T 29-03-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CSW12_RS07415 54d1a02d69cf6b93353488b251c8a413 262 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 113 131 - T 29-03-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70326 CSW12_RS07415 54d1a02d69cf6b93353488b251c8a413 262 SUPERFAMILY SSF100950 1 232 1.41E-85 T 29-03-2018 CSW12_RS07415 54d1a02d69cf6b93353488b251c8a413 262 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 10 220 3.6E-21 T 29-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 PIRSF PIRSF001413 1 397 4.5E-169 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 394 54.106 T 29-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 381 2.0E-45 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 Gene3D G3DSA:3.40.50.1100 202 397 1.1E-40 T 29-03-2018 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 SUPERFAMILY SSF53686 6 392 1.01E-148 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 Gene3D G3DSA:3.40.50.1100 12 68 1.0E-6 T 29-03-2018 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 Gene3D G3DSA:3.40.50.1100 69 201 2.9E-39 T 29-03-2018 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 29-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS05740 b3acfdf168fbe67087febf3cd4e72616 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 10 393 3.4E-197 T 29-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CSW12_RS22990 54362b31663b9663018cde94ed0e053e 288 Gene3D G3DSA:3.40.50.1820 12 280 4.7E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS22990 54362b31663b9663018cde94ed0e053e 288 SUPERFAMILY SSF53474 9 274 1.85E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS22990 54362b31663b9663018cde94ed0e053e 288 Pfam PF00561 alpha/beta hydrolase fold 48 263 4.2E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 Gene3D G3DSA:3.30.160.20 10 72 3.0E-32 T 29-03-2018 CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 29-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.021 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 SUPERFAMILY SSF54211 80 159 3.79E-26 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 7.8E-73 T 29-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 SUPERFAMILY SSF54768 9 76 1.36E-25 T 29-03-2018 CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 4.2E-33 T 29-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 Gene3D G3DSA:3.30.230.10 76 166 2.8E-33 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS28070 3149f812515dc415e17f9e6c3d36ddcc 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.7E-31 T 29-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CSW12_RS11200 ff4879e82829897caf45dd0edcc08181 350 Gene3D G3DSA:3.30.420.40 84 202 2.9E-15 T 29-03-2018 CSW12_RS11200 ff4879e82829897caf45dd0edcc08181 350 Gene3D G3DSA:3.30.420.40 203 257 5.9E-11 T 29-03-2018 CSW12_RS11200 ff4879e82829897caf45dd0edcc08181 350 Gene3D G3DSA:1.10.10.10 10 83 2.8E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11200 ff4879e82829897caf45dd0edcc08181 350 SUPERFAMILY SSF53067 93 288 2.53E-18 T 29-03-2018 CSW12_RS11200 ff4879e82829897caf45dd0edcc08181 350 SUPERFAMILY SSF46785 22 86 9.09E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11200 ff4879e82829897caf45dd0edcc08181 350 Pfam PF00480 ROK family 120 243 3.5E-17 T 29-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 PIRSF PIRSF000098 1 429 3.7E-168 T 29-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 29-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 SUPERFAMILY SSF51735 1 158 1.23E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 Pfam PF01842 ACT domain 351 403 3.9E-8 T 29-03-2018 IPR002912 ACT domain CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 355 397 0.002 T 29-03-2018 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 Gene3D G3DSA:3.30.360.10 158 298 9.6E-55 T 29-03-2018 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 Pfam PF00742 Homoserine dehydrogenase 137 315 2.8E-65 T 29-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 Gene3D G3DSA:3.30.70.260 349 421 3.2E-10 T 29-03-2018 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 SUPERFAMILY SSF55347 137 302 1.24E-52 T 29-03-2018 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 SUPERFAMILY SSF55021 348 414 4.58E-10 T 29-03-2018 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.8E-23 T 29-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CSW12_RS26805 eb8608d7992e85e0b042ffc5a73ad49c 431 Gene3D G3DSA:3.40.50.720 1 157 5.0E-34 T 29-03-2018 CSW12_RS11115 6f74f57fb7fe6dee8e29d9f9ae01f6f6 182 Hamap MF_01515 UPF0316 protein . 1 169 28.572 T 29-03-2018 IPR022930 Protein of unknown function UPF0316 CSW12_RS11115 6f74f57fb7fe6dee8e29d9f9ae01f6f6 182 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 109 161 6.3E-10 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Pfam PF13193 AMP-binding enzyme C-terminal domain 397 469 3.9E-22 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Gene3D G3DSA:3.30.300.30 382 482 1.6E-29 T 29-03-2018 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Gene3D G3DSA:2.30.38.10 298 380 6.8E-23 T 29-03-2018 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Gene3D G3DSA:3.40.50.980 1 150 3.6E-36 T 29-03-2018 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 5 478 49.432 T 29-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Gene3D G3DSA:3.40.50.980 151 297 1.9E-39 T 29-03-2018 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 Pfam PF00501 AMP-binding enzyme 14 387 2.3E-90 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 30 475 2.4E-146 T 29-03-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 CSW12_RS24000 d22059c88b765528e1c5a53319c14264 482 SUPERFAMILY SSF56801 4 481 2.75E-139 T 29-03-2018 CSW12_RS09815 e170be4cdf71d4b99178f5b88296ac16 570 Gene3D G3DSA:3.40.190.10 225 319 1.3E-20 T 29-03-2018 CSW12_RS09815 e170be4cdf71d4b99178f5b88296ac16 570 Gene3D G3DSA:3.90.76.10 64 224 6.3E-43 T 29-03-2018 CSW12_RS09815 e170be4cdf71d4b99178f5b88296ac16 570 PIRSF PIRSF002741 3 568 3.9E-109 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS09815 e170be4cdf71d4b99178f5b88296ac16 570 Gene3D G3DSA:3.10.105.10 320 536 9.9E-47 T 29-03-2018 CSW12_RS09815 e170be4cdf71d4b99178f5b88296ac16 570 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 480 2.1E-79 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS09815 e170be4cdf71d4b99178f5b88296ac16 570 SUPERFAMILY SSF53850 51 562 2.17E-126 T 29-03-2018 CSW12_RS02985 8e669eed3f2b310bc631be45bd93dcd0 256 Pfam PF05690 Thiazole biosynthesis protein ThiG 5 248 4.4E-107 T 29-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CSW12_RS02985 8e669eed3f2b310bc631be45bd93dcd0 256 Gene3D G3DSA:3.20.20.70 1 256 7.0E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS02985 8e669eed3f2b310bc631be45bd93dcd0 256 SUPERFAMILY SSF110399 1 239 8.37E-80 T 29-03-2018 CSW12_RS02985 8e669eed3f2b310bc631be45bd93dcd0 256 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 41.674 T 29-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 SUPERFAMILY SSF46785 3 61 2.09E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Gene3D G3DSA:2.30.30.100 280 323 6.4E-11 T 29-03-2018 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Gene3D G3DSA:1.10.10.10 2 65 5.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Gene3D G3DSA:3.30.930.10 66 278 2.0E-65 T 29-03-2018 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 326 38.763 T 29-03-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 SUPERFAMILY SSF50037 282 325 1.37E-5 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Pfam PF03099 Biotin/lipoate A/B protein ligase family 92 214 8.7E-20 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Pfam PF08279 HTH domain 6 60 1.1E-15 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 Pfam PF02237 Biotin protein ligase C terminal domain 280 324 3.6E-9 T 29-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 88 324 2.4E-70 T 29-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CSW12_RS19910 7798d657eb7391c50a166dfc2c37e257 326 SUPERFAMILY SSF55681 72 276 2.82E-62 T 29-03-2018 CSW12_RS04735 d858bec65559030e5687bb1a3b7275d0 117 Gene3D G3DSA:2.30.29.30 23 115 4.1E-4 T 29-03-2018 IPR011993 PH domain-like CSW12_RS04735 d858bec65559030e5687bb1a3b7275d0 117 Pfam PF14470 Bacterial PH domain 12 108 5.5E-19 T 29-03-2018 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 SUPERFAMILY SSF52490 12 208 6.8E-74 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 SMART SM00865 207 324 5.7E-52 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-52 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 373 39.692 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 SMART SM00864 13 205 1.9E-119 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 Gene3D G3DSA:3.40.50.1440 8 214 2.7E-48 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 SUPERFAMILY SSF55307 204 319 3.43E-43 T 29-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 Pfam PF12327 FtsZ family, C-terminal domain 222 316 5.2E-32 T 29-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 29-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 5 332 6.9E-139 T 29-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 1.0E-45 T 29-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CSW12_RS08225 e96578891391965b0b7dee1559543d6c 384 Gene3D G3DSA:3.30.1330.20 215 323 5.5E-45 T 29-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CSW12_RS21045 94d0c34aa512f6d514213ec59dc27a03 248 Pfam PF14181 YqfQ-like protein 35 248 4.1E-52 T 29-03-2018 IPR025571 YqfQ-like protein CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Pfam PF00672 HAMP domain 181 228 1.0E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 1.0E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 SMART SM00304 181 233 8.9E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Gene3D G3DSA:3.30.565.10 304 463 8.6E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Gene3D G3DSA:3.30.450.20 29 155 0.0016 T 29-03-2018 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 SUPERFAMILY SSF158472 181 229 1.57E-10 T 29-03-2018 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Gene3D G3DSA:1.10.287.130 239 296 2.8E-15 T 29-03-2018 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 SUPERFAMILY SSF55874 290 455 1.83E-48 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 SMART SM00387 345 457 2.2E-41 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 SMART SM00388 234 300 5.2E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Gene3D G3DSA:3.30.450.20 184 238 0.0021 T 29-03-2018 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 454 2.6E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 1.3E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 1.3E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 1.3E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.3E-20 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01955 099883c1f573f3631c546f79d0edf83f 463 SUPERFAMILY SSF47384 218 301 2.75E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 SUPERFAMILY SSF103473 237 433 5.75E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 SUPERFAMILY SSF103473 9 193 5.75E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 Gene3D G3DSA:1.20.1250.20 242 434 1.1E-22 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 Gene3D G3DSA:1.20.1250.20 2 194 6.9E-29 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 Pfam PF07690 Major Facilitator Superfamily 16 398 4.9E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 136 160 5.4E-27 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 222 240 5.4E-27 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 291 315 5.4E-27 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 5.4E-27 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 106 126 5.4E-27 T 29-03-2018 CSW12_RS22075 a1e6a8cfc7f33904395f59ec204341f4 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 161 185 5.4E-27 T 29-03-2018 CSW12_RS24320 4e66f9b829b60aff9727b474c5404504 383 SUPERFAMILY SSF53383 1 381 1.79E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS24320 4e66f9b829b60aff9727b474c5404504 383 Pfam PF00155 Aminotransferase class I and II 69 378 1.2E-37 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS24320 4e66f9b829b60aff9727b474c5404504 383 Gene3D G3DSA:3.90.1150.10 1 89 4.7E-15 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS24320 4e66f9b829b60aff9727b474c5404504 383 Gene3D G3DSA:3.90.1150.10 272 381 2.4E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS24320 4e66f9b829b60aff9727b474c5404504 383 Gene3D G3DSA:3.40.640.10 90 271 6.4E-28 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS24320 4e66f9b829b60aff9727b474c5404504 383 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 382 5.0E-143 T 29-03-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CSW12_RS15015 c6388df3886406d727f63f2728f1c9f3 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CSW12_RS15015 c6388df3886406d727f63f2728f1c9f3 262 Gene3D G3DSA:1.10.12.10 220 262 3.2E-17 T 29-03-2018 IPR014748 Crontonase, C-terminal CSW12_RS15015 c6388df3886406d727f63f2728f1c9f3 262 Gene3D G3DSA:3.90.226.10 7 219 2.9E-75 T 29-03-2018 CSW12_RS15015 c6388df3886406d727f63f2728f1c9f3 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 6.6E-72 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CSW12_RS15015 c6388df3886406d727f63f2728f1c9f3 262 SUPERFAMILY SSF52096 4 261 9.08E-86 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS27565 8c95854731a409f81e43fd5b363566dd 59 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 3.8E-7 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS27565 8c95854731a409f81e43fd5b363566dd 59 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS21340 f7494e3d6521a36c9d2f9b8d25e7de14 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.619 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21340 f7494e3d6521a36c9d2f9b8d25e7de14 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 5.6E-21 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21340 f7494e3d6521a36c9d2f9b8d25e7de14 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21340 f7494e3d6521a36c9d2f9b8d25e7de14 49 Pfam PF00471 Ribosomal protein L33 3 49 3.6E-23 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21340 f7494e3d6521a36c9d2f9b8d25e7de14 49 SUPERFAMILY SSF57829 1 49 1.83E-19 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 TIGRFAM TIGR01391 dnaG: DNA primase 4 419 1.2E-151 T 29-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Gene3D G3DSA:3.90.580.10 1 102 4.5E-36 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Pfam PF10410 DnaB-helicase binding domain of primase 371 420 2.7E-6 T 29-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 PIRSF PIRSF002811 2 598 1.1E-185 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Gene3D G3DSA:3.90.980.10 111 243 1.9E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 SMART SM00493 262 333 1.2E-18 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Gene3D G3DSA:3.40.1360.10 244 367 1.4E-35 T 29-03-2018 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Pfam PF13155 Toprim-like 265 349 8.1E-20 T 29-03-2018 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Hamap MF_00974 DNA primase [dnaG]. 4 589 29.235 T 29-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Gene3D G3DSA:1.10.860.10 463 562 9.5E-8 T 29-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Pfam PF01807 CHC2 zinc finger 6 98 1.0E-37 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 SUPERFAMILY SSF56731 118 425 6.28E-105 T 29-03-2018 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 255 1.0E-43 T 29-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 SMART SM00766 466 591 1.2E-19 T 29-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 SMART SM00400 36 90 3.7E-34 T 29-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CSW12_RS21075 d9f3cbcba172cbb9ebcb493c876120cf 598 SUPERFAMILY SSF57783 4 97 6.29E-36 T 29-03-2018 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 SUPERFAMILY SSF54680 331 432 3.01E-30 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 PIRSF PIRSF000478 1 432 3.2E-171 T 29-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 SMART SM00941 345 418 3.9E-32 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 418 2.6E-183 T 29-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 SUPERFAMILY SSF52418 69 329 7.06E-94 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 Gene3D G3DSA:3.40.1030.10 68 337 5.2E-95 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 Gene3D G3DSA:1.20.970.10 1 66 2.6E-24 T 29-03-2018 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 7.5E-27 T 29-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 3.2E-20 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 SUPERFAMILY SSF47648 1 69 9.68E-23 T 29-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 Gene3D G3DSA:3.90.1170.30 338 423 8.2E-29 T 29-03-2018 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 29-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS07245 b873c26b7a0d1870a16ffd37b1bf202d 434 Pfam PF00591 Glycosyl transferase family, a/b domain 77 306 6.6E-50 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 SUPERFAMILY SSF54364 20 93 2.35E-30 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 ProSitePatterns PS00938 Initiation factor 3 signature. 73 86 - T 29-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 22 91 7.8E-34 T 29-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 16 185 31.483 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 Gene3D G3DSA:3.10.20.80 17 93 1.6E-33 T 29-03-2018 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 SUPERFAMILY SSF55200 97 186 2.35E-33 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 98 183 1.8E-38 T 29-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 22 184 1.5E-76 T 29-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CSW12_RS22490 db67300f0426f43b9f08eb4627bfe413 186 Gene3D G3DSA:3.30.110.10 94 186 1.7E-36 T 29-03-2018 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 SUPERFAMILY SSF69189 299 388 6.67E-17 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 307 409 1.1E-13 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 4.0E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 141 4.0E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 151 164 4.0E-13 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 SMART SM00936 307 409 6.7E-16 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 35 287 2.5E-85 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 Gene3D G3DSA:2.60.410.10 309 409 2.4E-14 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 Gene3D G3DSA:3.40.710.10 28 307 4.8E-47 T 29-03-2018 CSW12_RS15555 53aa291902e2f5e1b0643b5f9bc6bb53 437 SUPERFAMILY SSF56601 4 307 2.42E-78 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 508 654 1.5E-16 T 29-03-2018 CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 SUPERFAMILY SSF49899 457 659 9.71E-28 T 29-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Gene3D G3DSA:3.60.21.10 38 318 2.9E-31 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 SUPERFAMILY SSF49265 350 444 1.36E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Gene3D G3DSA:1.20.1270.70 759 820 0.024 T 29-03-2018 CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 SUPERFAMILY SSF56300 52 315 5.16E-36 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Pfam PF00149 Calcineurin-like phosphoesterase 57 248 4.8E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Gene3D G3DSA:1.20.1270.90 655 758 0.021 T 29-03-2018 CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Gene3D G3DSA:2.60.120.200 456 654 2.2E-27 T 29-03-2018 CSW12_RS03420 ec30150b41ecbc2b4a5f76cca76cd3d4 824 Gene3D G3DSA:2.60.40.10 319 442 5.3E-8 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS20010 044012053543d4615586a4091d153ed8 370 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 61.965 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CSW12_RS20010 044012053543d4615586a4091d153ed8 370 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 357 5.4E-111 T 29-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CSW12_RS20010 044012053543d4615586a4091d153ed8 370 Pfam PF00155 Aminotransferase class I and II 30 352 1.0E-58 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS20010 044012053543d4615586a4091d153ed8 370 Gene3D G3DSA:3.90.1150.10 252 353 2.5E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20010 044012053543d4615586a4091d153ed8 370 Gene3D G3DSA:3.40.640.10 43 251 2.5E-43 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20010 044012053543d4615586a4091d153ed8 370 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CSW12_RS20010 044012053543d4615586a4091d153ed8 370 SUPERFAMILY SSF53383 14 358 5.42E-82 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.888 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 TIGRFAM TIGR00077 lspA: signal peptidase II 2 151 5.7E-47 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 Pfam PF01252 Signal peptidase (SPase) II 6 144 8.3E-40 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 1.3E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.3E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS08290 88d80abfb7b663c09d9ed745313da72e 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 1.3E-18 T 29-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 SUPERFAMILY SSF102114 26 175 8.89E-14 T 29-03-2018 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 238 2.7E-120 T 29-03-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 PIRSF PIRSF000370 2 238 1.5E-51 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 235 35.936 T 29-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 Pfam PF04055 Radical SAM superfamily 28 122 6.2E-12 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 Pfam PF13353 4Fe-4S single cluster domain 14 117 7.1E-10 T 29-03-2018 CSW12_RS06260 f892881e9b1bbcdac465508d02c6a26a 238 Gene3D G3DSA:3.80.30.20 21 207 3.2E-18 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Gene3D G3DSA:3.30.70.1350 208 291 1.3E-20 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Gene3D G3DSA:1.20.1510.10 12 207 4.1E-44 T 29-03-2018 CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 288 1.5E-19 T 29-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 SUPERFAMILY SSF160240 212 290 9.55E-22 T 29-03-2018 CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 Pfam PF01545 Cation efflux family 17 208 2.3E-49 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 SUPERFAMILY SSF161111 10 210 9.42E-54 T 29-03-2018 CSW12_RS16425 9e6bf609cd5f5eb3096edb5e8e9af2b1 296 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 289 1.1E-68 T 29-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 Gene3D G3DSA:1.20.1250.20 256 508 1.3E-35 T 29-03-2018 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 Pfam PF07690 Major Facilitator Superfamily 15 406 6.5E-58 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 489 3.2E-89 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 SUPERFAMILY SSF103473 245 416 5.58E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 SUPERFAMILY SSF103473 467 500 5.58E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 SUPERFAMILY SSF103473 10 196 5.58E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 5.6E-6 T 29-03-2018 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 5.6E-6 T 29-03-2018 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 5.6E-6 T 29-03-2018 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 355 375 5.6E-6 T 29-03-2018 CSW12_RS13290 bfaa8f2f4467ea60b0f3e842f626c45a 511 Gene3D G3DSA:1.20.1250.20 10 198 2.5E-40 T 29-03-2018 CSW12_RS03330 fbf7e731f0e1489f7d80beed5735ca1d 224 SMART SM00382 30 217 1.7E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS03330 fbf7e731f0e1489f7d80beed5735ca1d 224 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS03330 fbf7e731f0e1489f7d80beed5735ca1d 224 Gene3D G3DSA:3.40.50.300 1 223 6.6E-65 T 29-03-2018 CSW12_RS03330 fbf7e731f0e1489f7d80beed5735ca1d 224 SUPERFAMILY SSF52540 1 221 3.45E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03330 fbf7e731f0e1489f7d80beed5735ca1d 224 Pfam PF00005 ABC transporter 21 169 4.3E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18580 83f2ea343b7d64d8b56aa6e163fe3775 367 SMART SM00854 57 297 1.4E-84 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CSW12_RS18580 83f2ea343b7d64d8b56aa6e163fe3775 367 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 57 296 2.5E-70 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CSW12_RS18580 83f2ea343b7d64d8b56aa6e163fe3775 367 SUPERFAMILY SSF56300 56 338 7.27E-45 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS18580 83f2ea343b7d64d8b56aa6e163fe3775 367 Gene3D G3DSA:3.60.21.10 25 366 2.5E-53 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS27710 3e16335538871946d303093a8db559a5 290 ProSitePatterns PS00770 Aminotransferases class-IV signature. 178 207 - T 29-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS27710 3e16335538871946d303093a8db559a5 290 Gene3D G3DSA:3.20.10.10 108 255 4.6E-40 T 29-03-2018 CSW12_RS27710 3e16335538871946d303093a8db559a5 290 SUPERFAMILY SSF56752 1 272 1.23E-73 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS27710 3e16335538871946d303093a8db559a5 290 Gene3D G3DSA:3.30.470.10 1 107 1.7E-28 T 29-03-2018 CSW12_RS27710 3e16335538871946d303093a8db559a5 290 Pfam PF01063 Amino-transferase class IV 29 250 6.5E-56 T 29-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 Gene3D G3DSA:3.40.50.980 38 183 1.2E-30 T 29-03-2018 CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 Gene3D G3DSA:3.40.50.980 184 346 1.0E-40 T 29-03-2018 CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 520 1.6E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 Pfam PF00501 AMP-binding enzyme 23 436 1.4E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 SUPERFAMILY SSF56801 7 532 7.2E-134 T 29-03-2018 CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 Gene3D G3DSA:2.30.38.10 355 430 5.8E-17 T 29-03-2018 CSW12_RS09605 86f47c48c8234002a257ad3652016d7b 537 Gene3D G3DSA:3.30.300.30 431 535 2.6E-25 T 29-03-2018 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 PIRSF PIRSF006250 1 277 2.7E-97 T 29-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 Gene3D G3DSA:3.20.20.70 135 265 1.6E-45 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 Gene3D G3DSA:3.90.1170.20 1 134 8.0E-37 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 SUPERFAMILY SSF54675 2 108 3.06E-29 T 29-03-2018 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 SUPERFAMILY SSF51690 109 275 5.1E-59 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 275 7.5E-102 T 29-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 273 3.6E-63 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CSW12_RS21780 00bc2788e817a42159839063f8c6368c 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 107 3.9E-25 T 29-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 SMART SM00859 8 123 2.1E-44 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 Gene3D G3DSA:3.40.50.720 3 142 2.2E-36 T 29-03-2018 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 329 3.9E-58 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 343 38.655 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 SUPERFAMILY SSF55347 131 330 6.25E-75 T 29-03-2018 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 344 3.2E-160 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 Gene3D G3DSA:3.30.360.10 143 326 3.2E-72 T 29-03-2018 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 SUPERFAMILY SSF51735 7 158 2.38E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 PIRSF PIRSF000148 6 348 3.4E-130 T 29-03-2018 CSW12_RS08775 148777ecbcb272639b2153dbc80e69ab 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 122 1.5E-34 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 Gene3D G3DSA:3.30.310.20 8 127 2.5E-15 T 29-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 SUPERFAMILY SSF48150 116 302 2.51E-44 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 SMART SM00478 138 303 2.4E-25 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 Pfam PF07934 8-oxoguanine DNA glycosylase, N-terminal domain 35 133 7.8E-8 T 29-03-2018 IPR012904 8-oxoguanine DNA glycosylase, N-terminal GO:0003684|GO:0006289|GO:0008534 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357|Reactome: R-HSA-5649702 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 Gene3D G3DSA:1.10.340.30 128 249 3.7E-25 T 29-03-2018 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 ProSitePatterns PS00516 Alkylbase DNA glycosidases alkA family signature. 234 258 - T 29-03-2018 IPR000035 Alkylbase DNA glycosidase, conserved site GO:0003905|GO:0006281 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 Gene3D G3DSA:1.10.1670.10 253 302 4.7E-12 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CSW12_RS09080 3175fa12e47f42c13bd31a70ee4ad81a 303 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 137 285 1.8E-14 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 Gene3D G3DSA:3.50.50.60 263 354 7.9E-6 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.5E-7 T 29-03-2018 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 181 6.5E-7 T 29-03-2018 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 6.5E-7 T 29-03-2018 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 Gene3D G3DSA:3.50.50.60 93 240 2.5E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 318 2.1E-43 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 SUPERFAMILY SSF51905 2 41 2.36E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 SUPERFAMILY SSF51905 184 336 2.36E-20 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 Gene3D G3DSA:3.50.50.60 1 92 1.6E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 SUPERFAMILY SSF51905 1 207 2.37E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.3E-12 T 29-03-2018 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.3E-12 T 29-03-2018 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.3E-12 T 29-03-2018 CSW12_RS25155 543a815338f1f628e9a1e29fcc5e82a6 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.3E-12 T 29-03-2018 CSW12_RS19060 14e430a901a4380b5c1f1952df4b5875 136 Gene3D G3DSA:1.10.10.10 3 124 1.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19060 14e430a901a4380b5c1f1952df4b5875 136 Pfam PF01047 MarR family 23 81 1.9E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS19060 14e430a901a4380b5c1f1952df4b5875 136 SMART SM00347 16 116 1.2E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS19060 14e430a901a4380b5c1f1952df4b5875 136 SUPERFAMILY SSF46785 6 128 7.75E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 2.3E-97 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 1.1E-92 T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 PIRSF PIRSF001461 1 214 1.4E-101 T 29-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 29-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 Gene3D G3DSA:3.20.20.70 1 214 9.6E-93 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS08470 90713fc8264d2984e3efed21b885733b 214 SUPERFAMILY SSF51366 1 213 2.09E-81 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS10580 242e77ca6f8a4bd0e767a758b0d92a2b 183 Pfam PF13302 Acetyltransferase (GNAT) domain 13 150 4.5E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS10580 242e77ca6f8a4bd0e767a758b0d92a2b 183 Gene3D G3DSA:3.40.630.30 3 183 6.9E-26 T 29-03-2018 CSW12_RS10580 242e77ca6f8a4bd0e767a758b0d92a2b 183 SUPERFAMILY SSF55729 1 175 9.01E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 7 359 8.3E-153 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 SUPERFAMILY SSF53383 4 360 1.9E-84 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 3 362 7.7E-199 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 Gene3D G3DSA:3.40.640.10 22 255 4.9E-25 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 Pfam PF00266 Aminotransferase class-V 34 310 2.9E-27 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 PIRSF PIRSF000524 1 363 1.4E-52 T 29-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 Gene3D G3DSA:3.90.1150.10 256 362 3.6E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS06175 9d70f6963b474f6932933b14294cfed5 365 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 365 201.551 T 29-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 Pfam PF07690 Major Facilitator Superfamily 250 427 4.2E-12 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 Gene3D G3DSA:1.20.1250.20 220 437 4.2E-24 T 29-03-2018 CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 SUPERFAMILY SSF103473 13 420 2.22E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 ProSitePatterns PS00216 Sugar transport proteins signature 1. 291 308 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 Pfam PF00083 Sugar (and other) transporter 17 235 7.9E-28 T 29-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CSW12_RS03890 2007a8e18440b78426792fabcdcbbc24 439 Gene3D G3DSA:1.20.1250.20 12 219 2.0E-25 T 29-03-2018 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Pfam PF02743 Cache domain 47 264 3.1E-29 T 29-03-2018 IPR033479 Double Cache domain 1 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Gene3D G3DSA:1.10.287.950 331 409 2.1E-9 T 29-03-2018 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 SUPERFAMILY SSF103190 94 190 1.33E-8 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 SMART SM00283 363 659 1.2E-79 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Gene3D G3DSA:3.30.450.20 47 165 1.6E-14 T 29-03-2018 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Pfam PF00672 HAMP domain 304 351 7.7E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 430 610 1.2E-51 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 SMART SM00304 579 656 69.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 SMART SM00304 303 355 1.1E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Gene3D G3DSA:1.10.287.950 410 660 3.1E-56 T 29-03-2018 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 Gene3D G3DSA:3.30.450.20 166 272 2.2E-16 T 29-03-2018 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 SUPERFAMILY SSF58104 390 659 2.35E-77 T 29-03-2018 CSW12_RS17815 463d3235bef06e266abc8ca5d1b3c0ba 660 SUPERFAMILY SSF58104 323 357 2.35E-77 T 29-03-2018 CSW12_RS16605 01b0a68d6d2e506e77ffcf0a0a1e8226 254 Pfam PF10924 Protein of unknown function (DUF2711) 38 253 5.8E-114 T 29-03-2018 IPR024250 Protein of unknown function DUF2711 CSW12_RS16605 01b0a68d6d2e506e77ffcf0a0a1e8226 254 ProDom PD114754 YWBB 30 253 8.0E-115 T 29-03-2018 IPR024250 Protein of unknown function DUF2711 CSW12_RS15730 fe39429eeb2ec6c52aaac788df84c831 182 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 176 14.467 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS15730 fe39429eeb2ec6c52aaac788df84c831 182 Pfam PF02660 Glycerol-3-phosphate acyltransferase 13 178 6.6E-38 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS15730 fe39429eeb2ec6c52aaac788df84c831 182 SMART SM01207 11 176 5.4E-47 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS00105 e5f2df39f5f42610c99f239c46c7ebf8 229 SUPERFAMILY SSF51395 6 223 9.16E-56 T 29-03-2018 CSW12_RS00105 e5f2df39f5f42610c99f239c46c7ebf8 229 Gene3D G3DSA:3.20.20.390 2 224 5.9E-31 T 29-03-2018 CSW12_RS00105 e5f2df39f5f42610c99f239c46c7ebf8 229 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.157 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CSW12_RS00105 e5f2df39f5f42610c99f239c46c7ebf8 229 Pfam PF01884 PcrB family 2 226 3.6E-87 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CSW12_RS00105 e5f2df39f5f42610c99f239c46c7ebf8 229 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 1.1E-75 T 29-03-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 SUPERFAMILY SSF53335 81 393 6.44E-65 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 SUPERFAMILY SSF88697 6 74 1.37E-20 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 Gene3D G3DSA:2.30.130.10 6 69 5.0E-20 T 29-03-2018 IPR002478 PUA domain GO:0003723 CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 SMART SM00359 5 90 1.2E-5 T 29-03-2018 IPR002478 PUA domain GO:0003723 CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 Gene3D G3DSA:3.30.750.80 74 181 4.7E-32 T 29-03-2018 CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 Gene3D G3DSA:3.40.50.150 183 398 2.9E-23 T 29-03-2018 CSW12_RS22310 469111bb377231834570e649cfd0eb6b 399 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 112 381 1.2E-30 T 29-03-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CSW12_RS07150 e4c83956deadb32fa4f157554219f059 439 PRINTS PR00173 Glutamate-aspartate symporter signature 372 391 9.5E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS07150 e4c83956deadb32fa4f157554219f059 439 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 9.5E-5 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS07150 e4c83956deadb32fa4f157554219f059 439 Pfam PF03553 Na+/H+ antiporter family 151 433 2.6E-68 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CSW12_RS07150 e4c83956deadb32fa4f157554219f059 439 Pfam PF13726 Na+-H+ antiporter family 2 88 6.6E-33 T 29-03-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SUPERFAMILY SSF48403 86 278 1.13E-49 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 PRINTS PR01415 Ankyrin repeat signature 236 250 2.2E-7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 PRINTS PR01415 Ankyrin repeat signature 182 197 2.2E-7 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SMART SM00248 215 249 0.18 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SMART SM00248 115 144 0.0018 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SMART SM00248 83 111 1700.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SMART SM00248 148 177 0.096 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SMART SM00248 181 211 0.042 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 SMART SM00248 253 283 270.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 Gene3D G3DSA:1.25.40.20 59 158 5.9E-22 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 Gene3D G3DSA:1.20.120.660 159 240 4.6E-23 T 29-03-2018 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 Gene3D G3DSA:1.20.120.660 241 288 2.0E-10 T 29-03-2018 CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 Pfam PF12796 Ankyrin repeats (3 copies) 146 213 5.4E-12 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS01530 c12b22c1c4ac8d51c3f9c19a1b92bb90 289 Pfam PF13637 Ankyrin repeats (many copies) 231 273 9.6E-8 T 29-03-2018 CSW12_RS03990 65ce08b853f6b1cf400205ecb03f6d5d 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 64 8.6E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS03990 65ce08b853f6b1cf400205ecb03f6d5d 191 Gene3D G3DSA:1.10.10.60 13 50 3.2E-9 T 29-03-2018 CSW12_RS03990 65ce08b853f6b1cf400205ecb03f6d5d 191 Gene3D G3DSA:1.10.260.40 51 136 1.6E-6 T 29-03-2018 CSW12_RS03990 65ce08b853f6b1cf400205ecb03f6d5d 191 SUPERFAMILY SSF46689 10 76 2.24E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS16080 33b15f677d387437b2ea48ee7174ace3 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 280 4.8E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16080 33b15f677d387437b2ea48ee7174ace3 286 Gene3D G3DSA:1.10.3720.10 65 285 1.1E-13 T 29-03-2018 CSW12_RS16080 33b15f677d387437b2ea48ee7174ace3 286 SUPERFAMILY SSF161098 70 265 3.71E-6 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 SUPERFAMILY SSF143597 17 143 2.88E-28 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 26 137 1.4E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 6 354 44.958 T 29-03-2018 IPR023763 DNA integrity scanning protein, DisA CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 Pfam PF10635 DisA bacterial checkpoint controller linker region 143 281 8.7E-51 T 29-03-2018 IPR018906 DNA integrity scanning, DisA, linker region CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 Gene3D G3DSA:3.40.1700.10 7 143 5.1E-26 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 SUPERFAMILY SSF47781 241 345 8.53E-13 T 29-03-2018 IPR010994 RuvA domain 2-like CSW12_RS27845 f75f31b3e70d166158d9f97e7fc5657b 357 Gene3D G3DSA:1.10.150.20 294 349 1.2E-8 T 29-03-2018 CSW12_RS29820 f07a1585c8d915e6eb6cf869a9ec38f9 76 SUPERFAMILY SSF47413 15 60 2.66E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS29820 f07a1585c8d915e6eb6cf869a9ec38f9 76 Gene3D G3DSA:1.10.260.40 36 69 9.0E-5 T 29-03-2018 CSW12_RS29820 f07a1585c8d915e6eb6cf869a9ec38f9 76 Gene3D G3DSA:1.10.10.60 14 35 1.4E-5 T 29-03-2018 CSW12_RS29820 f07a1585c8d915e6eb6cf869a9ec38f9 76 Pfam PF01381 Helix-turn-helix 18 59 1.5E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 Gene3D G3DSA:1.10.150.130 1 109 1.9E-22 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 296 5.0E-103 T 29-03-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 88 2.1E-21 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 62.878 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 59.125 T 29-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 SUPERFAMILY SSF56349 2 288 1.8E-63 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 3.2E-126 T 29-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 Gene3D G3DSA:1.10.443.10 110 290 2.7E-54 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS07225 dd60d4664112931fee77889cf7de30da 296 Pfam PF00589 Phage integrase family 110 282 2.3E-56 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 Gene3D G3DSA:3.30.930.10 123 462 1.0E-97 T 29-03-2018 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 457 2.2E-88 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 SUPERFAMILY SSF50249 13 102 7.91E-20 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 463 1.5E-190 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 6 463 46.224 T 29-03-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 Gene3D G3DSA:2.40.50.140 6 108 5.3E-21 T 29-03-2018 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 Pfam PF01336 OB-fold nucleic acid binding domain 21 97 1.4E-10 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 SUPERFAMILY SSF55681 104 460 2.05E-99 T 29-03-2018 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 378 394 2.9E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 418 432 2.9E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 205 217 2.9E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS22410 4b4912bef9c323594bf2a04b65bd3a08 463 PRINTS PR01042 Aspartyl-tRNA synthetase signature 221 234 2.9E-12 T 29-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS01160 db167433747b7371d4023bf2d73e4110 388 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 179 1.3E-40 T 29-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CSW12_RS01160 db167433747b7371d4023bf2d73e4110 388 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 1 388 57.578 T 29-03-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-6778|MetaCyc: PWY-7817 CSW12_RS01160 db167433747b7371d4023bf2d73e4110 388 Gene3D G3DSA:3.40.50.2000 2 178 1.3E-9 T 29-03-2018 CSW12_RS01160 db167433747b7371d4023bf2d73e4110 388 Gene3D G3DSA:3.40.50.2000 179 359 4.1E-23 T 29-03-2018 CSW12_RS01160 db167433747b7371d4023bf2d73e4110 388 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 220 348 1.1E-12 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CSW12_RS01160 db167433747b7371d4023bf2d73e4110 388 SUPERFAMILY SSF53756 6 366 3.14E-34 T 29-03-2018 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 PRINTS PR00154 AMP-binding signature 164 175 6.5E-5 T 29-03-2018 IPR020459 AMP-binding CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 PRINTS PR00154 AMP-binding signature 176 184 6.5E-5 T 29-03-2018 IPR020459 AMP-binding CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 Gene3D G3DSA:3.40.50.980 175 325 3.5E-54 T 29-03-2018 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 Gene3D G3DSA:3.40.50.980 2 174 2.4E-43 T 29-03-2018 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 Gene3D G3DSA:3.30.300.30 408 510 3.3E-29 T 29-03-2018 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 423 497 8.6E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 Pfam PF00501 AMP-binding enzyme 8 414 4.2E-117 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 SUPERFAMILY SSF56801 2 509 3.27E-163 T 29-03-2018 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 Gene3D G3DSA:2.30.38.10 326 407 4.8E-28 T 29-03-2018 CSW12_RS04770 39fdbf94c949e166d3e83aa375f4ee36 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS19805 c8047c08a7761eb23416527814915d6b 140 Pfam PF11122 Inner spore coat protein D 22 115 3.5E-23 T 29-03-2018 IPR020108 Spore coat protein CotD CSW12_RS19805 c8047c08a7761eb23416527814915d6b 140 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 22 72 1.0E-20 T 29-03-2018 IPR020108 Spore coat protein CotD CSW12_RS25330 24e8eab6b9476f8f27de35e7206e73d7 122 Pfam PF03788 LrgA family 18 109 4.5E-23 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 SUPERFAMILY SSF48557 12 468 4.56E-148 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 3.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00149 Fumarate lyase superfamily signature 186 204 3.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00149 Fumarate lyase superfamily signature 277 304 3.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00149 Fumarate lyase superfamily signature 323 339 3.5E-32 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 ProSitePatterns PS00163 Fumarate lyases signature. 323 332 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 Gene3D G3DSA:1.10.40.30 422 471 1.1E-21 T 29-03-2018 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 Pfam PF10415 Fumarase C C-terminus 414 467 1.1E-20 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 Gene3D G3DSA:1.10.275.10 9 144 1.3E-54 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 Gene3D G3DSA:1.20.200.10 145 421 6.9E-80 T 29-03-2018 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 Pfam PF00206 Lyase 19 348 8.1E-110 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 12 473 4.0E-233 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00145 Argininosuccinate lyase family signature 140 162 2.6E-7 T 29-03-2018 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00145 Argininosuccinate lyase family signature 181 201 2.6E-7 T 29-03-2018 CSW12_RS18815 cf2ec9f25ec78cc489c9460428fe878a 479 PRINTS PR00145 Argininosuccinate lyase family signature 323 339 2.6E-7 T 29-03-2018 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 SUPERFAMILY SSF51735 7 259 3.36E-74 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 0.007 T 29-03-2018 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 9.8E-121 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 2.6E-62 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 2.6E-62 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 2.6E-62 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 2.6E-62 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 2.6E-62 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 2.6E-62 T 29-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.3E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 Pfam PF00106 short chain dehydrogenase 9 201 2.3E-59 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS16190 ef693bfd9b326df850d895bbfa5dac62 261 Gene3D G3DSA:3.40.50.720 1 260 1.9E-69 T 29-03-2018 CSW12_RS01620 32822ab1cdcb29df6901ab1e3e2ae547 308 SUPERFAMILY SSF103481 192 297 7.85E-14 T 29-03-2018 CSW12_RS01620 32822ab1cdcb29df6901ab1e3e2ae547 308 SUPERFAMILY SSF103481 43 148 1.57E-8 T 29-03-2018 CSW12_RS01620 32822ab1cdcb29df6901ab1e3e2ae547 308 Pfam PF00892 EamA-like transporter family 7 146 3.1E-16 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS01620 32822ab1cdcb29df6901ab1e3e2ae547 308 Pfam PF00892 EamA-like transporter family 159 293 3.2E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 327 44.645 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 SUPERFAMILY SSF51735 1 181 4.44E-73 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 182 325 9.1E-67 T 29-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 Gene3D G3DSA:1.10.1040.10 63 329 1.3E-118 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 Gene3D G3DSA:3.90.180.10 5 62 1.5E-4 T 29-03-2018 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 SUPERFAMILY SSF48179 182 328 1.87E-70 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 325 1.4E-140 T 29-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 PIRSF PIRSF000116 200 330 6.7E-15 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 PIRSF PIRSF000116 2 203 8.0E-44 T 29-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS18600 f9fe817cdb3964898aab1f73b93a2ae4 335 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 176 8.4E-77 T 29-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 SUPERFAMILY SSF56601 1 287 4.39E-85 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS07295 975e90f1556701191069006c36f6d271 396 SUPERFAMILY SSF69189 279 376 5.1E-20 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 1.3E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 1.3E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.3E-17 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 37 267 4.8E-90 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 Gene3D G3DSA:3.40.710.10 21 288 1.8E-54 T 29-03-2018 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 Gene3D G3DSA:2.60.410.10 289 378 2.7E-20 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 SMART SM00936 287 378 5.4E-21 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS07295 975e90f1556701191069006c36f6d271 396 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 287 377 7.7E-20 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS24705 312d289306dcfc76384e1dfb8a99ff7c 143 SUPERFAMILY SSF82649 2 141 2.72E-52 T 29-03-2018 CSW12_RS24705 312d289306dcfc76384e1dfb8a99ff7c 143 Gene3D G3DSA:3.90.1010.10 3 140 1.1E-50 T 29-03-2018 CSW12_RS24705 312d289306dcfc76384e1dfb8a99ff7c 143 Pfam PF01592 NifU-like N terminal domain 10 127 2.5E-37 T 29-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CSW12_RS24705 312d289306dcfc76384e1dfb8a99ff7c 143 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 139 1.6E-56 T 29-03-2018 CSW12_RS03840 5d1f84806b4fcbd6cf29873be1c1353e 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 276 3.0E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03840 5d1f84806b4fcbd6cf29873be1c1353e 283 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 7 55 4.0E-6 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CSW12_RS03840 5d1f84806b4fcbd6cf29873be1c1353e 283 SUPERFAMILY SSF161098 75 261 9.68E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03840 5d1f84806b4fcbd6cf29873be1c1353e 283 Gene3D G3DSA:1.10.3720.10 4 268 1.1E-43 T 29-03-2018 CSW12_RS05440 7889de263fbdb41b2ca8df948739fe6a 543 PIRSF PIRSF002741 1 543 9.7E-105 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS05440 7889de263fbdb41b2ca8df948739fe6a 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 464 2.4E-73 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS05440 7889de263fbdb41b2ca8df948739fe6a 543 Gene3D G3DSA:3.40.190.10 176 308 9.4E-36 T 29-03-2018 CSW12_RS05440 7889de263fbdb41b2ca8df948739fe6a 543 SUPERFAMILY SSF53850 36 538 7.6E-122 T 29-03-2018 CSW12_RS05440 7889de263fbdb41b2ca8df948739fe6a 543 Gene3D G3DSA:3.90.76.10 55 175 9.6E-35 T 29-03-2018 CSW12_RS05440 7889de263fbdb41b2ca8df948739fe6a 543 Gene3D G3DSA:3.10.105.10 309 512 8.9E-45 T 29-03-2018 CSW12_RS26410 3b592b0dfd06c6e85902a44a3df1f753 182 Pfam PF02659 Putative manganese efflux pump 33 179 2.4E-39 T 29-03-2018 IPR003810 Putative manganese efflux pump CSW12_RS26410 3b592b0dfd06c6e85902a44a3df1f753 182 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 4 182 21.587 T 29-03-2018 IPR022929 Putative manganese efflux pump MntP CSW12_RS20915 6ec4bacc6efc5e3a647296a6c73d0964 209 Pfam PF00753 Metallo-beta-lactamase superfamily 9 192 8.7E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20915 6ec4bacc6efc5e3a647296a6c73d0964 209 SUPERFAMILY SSF56281 1 209 1.14E-53 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20915 6ec4bacc6efc5e3a647296a6c73d0964 209 Gene3D G3DSA:3.60.15.10 1 209 3.3E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS20915 6ec4bacc6efc5e3a647296a6c73d0964 209 SMART SM00849 12 192 3.4E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS09845 9b472fdc8b8f7e1b8a474ae315d4b7a7 112 Gene3D G3DSA:3.10.180.10 2 112 4.9E-16 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09845 9b472fdc8b8f7e1b8a474ae315d4b7a7 112 SUPERFAMILY SSF54593 2 112 1.75E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09845 9b472fdc8b8f7e1b8a474ae315d4b7a7 112 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 110 1.2E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS04355 dd2b9f623ebd1f898c2eb47c2a373ab2 376 Pfam PF07282 Putative transposase DNA-binding domain 300 372 2.7E-18 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CSW12_RS04355 dd2b9f623ebd1f898c2eb47c2a373ab2 376 Pfam PF12323 Helix-turn-helix domain 1 45 1.1E-11 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CSW12_RS04355 dd2b9f623ebd1f898c2eb47c2a373ab2 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 250 323 2.8E-8 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CSW12_RS04355 dd2b9f623ebd1f898c2eb47c2a373ab2 376 Pfam PF01385 Probable transposase 170 283 4.4E-14 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CSW12_RS03680 dd2b9f623ebd1f898c2eb47c2a373ab2 376 Pfam PF07282 Putative transposase DNA-binding domain 300 372 2.7E-18 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CSW12_RS03680 dd2b9f623ebd1f898c2eb47c2a373ab2 376 Pfam PF12323 Helix-turn-helix domain 1 45 1.1E-11 T 29-03-2018 IPR021027 Transposase, putative, helix-turn-helix domain CSW12_RS03680 dd2b9f623ebd1f898c2eb47c2a373ab2 376 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 250 323 2.8E-8 T 29-03-2018 IPR010095 Transposase IS605, OrfB, C-terminal CSW12_RS03680 dd2b9f623ebd1f898c2eb47c2a373ab2 376 Pfam PF01385 Probable transposase 170 283 4.4E-14 T 29-03-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 SMART SM00347 24 124 4.1E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 SUPERFAMILY SSF46785 7 136 1.48E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 Pfam PF01047 MarR family 32 88 4.9E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 8.5E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 8.5E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 8.5E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 8.5E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS11895 966df1429830887a5d0ff75a1de5cfa8 139 Gene3D G3DSA:1.10.10.10 1 138 6.6E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07585 139c9a14b79591422d4e98c8776f59e0 384 Pfam PF00155 Aminotransferase class I and II 57 365 3.6E-12 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS07585 139c9a14b79591422d4e98c8776f59e0 384 Gene3D G3DSA:3.40.640.10 66 251 3.6E-17 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS07585 139c9a14b79591422d4e98c8776f59e0 384 Gene3D G3DSA:3.90.1150.10 252 376 2.2E-8 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS07585 139c9a14b79591422d4e98c8776f59e0 384 SUPERFAMILY SSF53383 72 371 1.06E-32 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS04050 bc4acb243be554d092316af41055a2ec 460 SUPERFAMILY SSF53474 146 457 5.87E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS04050 bc4acb243be554d092316af41055a2ec 460 Gene3D G3DSA:3.40.50.1820 133 460 2.3E-30 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS04050 bc4acb243be554d092316af41055a2ec 460 Pfam PF12697 Alpha/beta hydrolase family 194 422 3.8E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS22020 ea1338bdd0c8375f497e7c770c72c651 204 Gene3D G3DSA:2.30.29.50 21 112 6.8E-32 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CSW12_RS22020 ea1338bdd0c8375f497e7c770c72c651 204 Pfam PF11724 YvbH-like oligomerisation region 144 204 1.1E-26 T 29-03-2018 IPR021722 Uncharacterised domain YvbH-like, oligomerisation domain CSW12_RS22020 ea1338bdd0c8375f497e7c770c72c651 204 Gene3D G3DSA:1.10.287.210 116 204 5.2E-33 T 29-03-2018 CSW12_RS22020 ea1338bdd0c8375f497e7c770c72c651 204 Pfam PF08000 Bacterial PH domain 11 131 2.8E-37 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CSW12_RS22020 ea1338bdd0c8375f497e7c770c72c651 204 SUPERFAMILY SSF50729 14 203 3.01E-68 T 29-03-2018 IPR011993 PH domain-like CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 SUPERFAMILY SSF158745 511 842 4.97E-27 T 29-03-2018 CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 Gene3D G3DSA:1.10.510.10 310 532 3.2E-12 T 29-03-2018 CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 Gene3D G3DSA:1.50.10.20 533 708 1.2E-5 T 29-03-2018 CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 SUPERFAMILY SSF56112 221 422 1.78E-24 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 Pfam PF00069 Protein kinase domain 234 410 6.7E-16 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 SMART SM01260 515 838 9.0E-5 T 29-03-2018 IPR007822 Lanthionine synthetase C-like CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 Gene3D G3DSA:3.30.200.20 214 309 3.8E-6 T 29-03-2018 CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 Gene3D G3DSA:3.30.2430.10 7 175 1.3E-35 T 29-03-2018 CSW12_RS27070 dcbca844c62f5da2d495d857a775e4c2 867 SMART SM00220 223 477 0.0025 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 Gene3D G3DSA:3.40.50.300 158 333 4.7E-35 T 29-03-2018 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.4E-34 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 SUPERFAMILY SSF52540 160 334 1.32E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.3E-22 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 Gene3D G3DSA:2.70.210.12 1 155 4.5E-58 T 29-03-2018 IPR006169 GTP1/OBG domain CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 SUPERFAMILY SSF102741 357 428 1.96E-23 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 6.2E-25 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 2.2E-26 T 29-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 Pfam PF01018 GTP1/OBG 3 157 3.0E-59 T 29-03-2018 IPR006169 GTP1/OBG domain CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 SUPERFAMILY SSF82051 1 157 2.35E-54 T 29-03-2018 IPR006169 GTP1/OBG domain CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 2.9E-142 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 47.935 T 29-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 3.2E-14 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 29-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CSW12_RS21835 e70618b5d6c3a99d6b60cbe6ea8954aa 428 PIRSF PIRSF002401 1 375 1.7E-141 T 29-03-2018 IPR035101 GTP-binding protein, Obg-type CSW12_RS13960 a4db701306b1581f1c83beebe0910c23 165 Gene3D G3DSA:3.40.630.30 3 164 3.5E-13 T 29-03-2018 CSW12_RS13960 a4db701306b1581f1c83beebe0910c23 165 SUPERFAMILY SSF55729 8 151 3.23E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13960 a4db701306b1581f1c83beebe0910c23 165 Pfam PF00583 Acetyltransferase (GNAT) family 36 142 4.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 4.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.4E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.1E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 SUPERFAMILY SSF51735 3 250 1.18E-77 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 249 8.5E-56 T 29-03-2018 CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 Gene3D G3DSA:3.40.50.720 38 252 4.9E-58 T 29-03-2018 CSW12_RS18620 67b6579ac30659e7a638233aa1ccc4cf 252 Gene3D G3DSA:3.40.50.720 1 37 2.9E-10 T 29-03-2018 CSW12_RS28450 e46e844d59ca961f54cdda849f22eda9 224 Gene3D G3DSA:1.10.3720.10 2 223 1.5E-38 T 29-03-2018 CSW12_RS28450 e46e844d59ca961f54cdda849f22eda9 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 222 7.5E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28450 e46e844d59ca961f54cdda849f22eda9 224 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 12 220 1.8E-79 T 29-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CSW12_RS28450 e46e844d59ca961f54cdda849f22eda9 224 SUPERFAMILY SSF161098 6 217 2.75E-48 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 Pfam PF00117 Glutamine amidotransferase class-I 3 187 5.9E-53 T 29-03-2018 IPR017926 Glutamine amidotransferase CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 SUPERFAMILY SSF52317 1 186 1.45E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.8E-14 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.8E-14 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.8E-14 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 9.4E-71 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.3E-8 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 2.3E-8 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 Gene3D G3DSA:3.40.50.880 1 192 4.0E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.1E-35 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.1E-35 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.1E-35 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.1E-35 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00097 Anthranilate synthase component II signature 165 178 4.1E-35 T 29-03-2018 CSW12_RS05720 b578ec47c0d59d7f0ee9093573783ecd 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.1E-35 T 29-03-2018 CSW12_RS20935 9201955b250077f125dca5f64456080b 192 PIRSF PIRSF006806 1 185 2.9E-47 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CSW12_RS20935 9201955b250077f125dca5f64456080b 192 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 182 1.9E-44 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CSW12_RS20935 9201955b250077f125dca5f64456080b 192 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 5 182 9.5E-58 T 29-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CSW12_RS20935 9201955b250077f125dca5f64456080b 192 SUPERFAMILY SSF100950 4 188 1.23E-50 T 29-03-2018 CSW12_RS20935 9201955b250077f125dca5f64456080b 192 Gene3D G3DSA:3.40.50.10420 1 192 1.2E-56 T 29-03-2018 CSW12_RS11640 8afc44b183867d361b8848d23663212a 419 SUPERFAMILY SSF103473 5 393 3.01E-33 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11640 8afc44b183867d361b8848d23663212a 419 Pfam PF05977 Transmembrane secretion effector 4 406 4.7E-26 T 29-03-2018 IPR010290 Transmembrane secretion effector CSW12_RS11640 8afc44b183867d361b8848d23663212a 419 Gene3D G3DSA:1.20.1250.20 206 403 1.8E-10 T 29-03-2018 CSW12_RS11640 8afc44b183867d361b8848d23663212a 419 Gene3D G3DSA:1.20.1250.20 1 202 5.5E-14 T 29-03-2018 CSW12_RS09780 b1cf06b8e0ea8aa08cb061deaeef49ec 322 Pfam PF08279 HTH domain 14 66 5.1E-10 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS09780 b1cf06b8e0ea8aa08cb061deaeef49ec 322 Gene3D G3DSA:1.10.10.10 5 72 8.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09780 b1cf06b8e0ea8aa08cb061deaeef49ec 322 Pfam PF13280 WYL domain 147 310 2.8E-14 T 29-03-2018 IPR026881 WYL domain CSW12_RS09780 b1cf06b8e0ea8aa08cb061deaeef49ec 322 SUPERFAMILY SSF46785 9 61 5.77E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09780 b1cf06b8e0ea8aa08cb061deaeef49ec 322 SMART SM00420 14 67 0.0019 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 Gene3D G3DSA:2.160.20.50 157 227 2.9E-19 T 29-03-2018 CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 Gene3D G3DSA:2.160.20.50 27 92 5.9E-20 T 29-03-2018 CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 Gene3D G3DSA:2.160.20.50 93 156 3.1E-20 T 29-03-2018 CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 Pfam PF13799 Domain of unknown function (DUF4183) 233 302 1.8E-20 T 29-03-2018 IPR025237 Domain of unknown function DUF4183 CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 14 32 1.7E-6 T 29-03-2018 IPR021201 Leader peptide, exosporium CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 Pfam PF01391 Collagen triple helix repeat (20 copies) 33 88 4.0E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS15820 d343c011a048341aad9b7e9707385659 306 Pfam PF01391 Collagen triple helix repeat (20 copies) 164 218 1.8E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS27585 81e573045aac7cf1746daa9af704f03e 97 Pfam PF04026 SpoVG 1 81 9.0E-36 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CSW12_RS27585 81e573045aac7cf1746daa9af704f03e 97 SUPERFAMILY SSF160537 1 86 2.09E-33 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CSW12_RS27585 81e573045aac7cf1746daa9af704f03e 97 Gene3D G3DSA:3.30.1120.40 1 83 5.9E-36 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CSW12_RS27585 81e573045aac7cf1746daa9af704f03e 97 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 95 28.22 T 29-03-2018 IPR007170 Stage V sporulation protein G GO:0030435 CSW12_RS03835 5dec38c5c4975624aeccb5a997e437ce 316 SUPERFAMILY SSF161098 92 296 3.92E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03835 5dec38c5c4975624aeccb5a997e437ce 316 Gene3D G3DSA:1.10.3720.10 2 302 2.5E-41 T 29-03-2018 CSW12_RS03835 5dec38c5c4975624aeccb5a997e437ce 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 7.1E-47 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS10160 6bc927f8c9a03760a3f137f032eadea3 247 Gene3D G3DSA:3.30.1380.10 94 226 1.2E-39 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS10160 6bc927f8c9a03760a3f137f032eadea3 247 SUPERFAMILY SSF55166 84 231 1.18E-37 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS10160 6bc927f8c9a03760a3f137f032eadea3 247 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 100 228 3.6E-48 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CSW12_RS10530 be78bed724eaf83d71dd4c5a6e58e11c 158 Pfam PF10901 Protein of unknown function (DUF2690) 35 139 6.8E-36 T 29-03-2018 IPR021224 Protein of unknown function DUF2690 CSW12_RS01290 102e0cff9243ee754226196427a84d8e 139 Pfam PF13673 Acetyltransferase (GNAT) domain 27 128 2.5E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS01290 102e0cff9243ee754226196427a84d8e 139 Gene3D G3DSA:3.40.630.30 1 131 5.5E-16 T 29-03-2018 CSW12_RS01290 102e0cff9243ee754226196427a84d8e 139 SUPERFAMILY SSF55729 12 129 1.18E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS03520 901109f400835a9bb1250cfc908387af 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 48 2.4E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS03520 901109f400835a9bb1250cfc908387af 192 SUPERFAMILY SSF46689 3 62 1.3E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS03520 901109f400835a9bb1250cfc908387af 192 Gene3D G3DSA:1.10.357.10 3 191 1.6E-33 T 29-03-2018 CSW12_RS03520 901109f400835a9bb1250cfc908387af 192 SUPERFAMILY SSF48498 77 172 2.97E-13 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS03520 901109f400835a9bb1250cfc908387af 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS03520 901109f400835a9bb1250cfc908387af 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.8E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS15095 493d051b5d6c75bfa4e4a21f963a9981 586 SUPERFAMILY SSF56601 169 574 1.34E-58 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS15095 493d051b5d6c75bfa4e4a21f963a9981 586 SUPERFAMILY SSF56519 32 214 2.09E-31 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS15095 493d051b5d6c75bfa4e4a21f963a9981 586 Gene3D G3DSA:3.40.710.10 216 585 4.0E-65 T 29-03-2018 CSW12_RS15095 493d051b5d6c75bfa4e4a21f963a9981 586 Gene3D G3DSA:3.90.1310.10 29 215 1.2E-25 T 29-03-2018 CSW12_RS15095 493d051b5d6c75bfa4e4a21f963a9981 586 Pfam PF03717 Penicillin-binding Protein dimerisation domain 37 203 4.9E-31 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS15095 493d051b5d6c75bfa4e4a21f963a9981 586 Pfam PF00905 Penicillin binding protein transpeptidase domain 241 567 1.7E-43 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS00860 4beff19817580f4ae457b9bb9f75aa3c 83 SUPERFAMILY SSF47413 21 81 1.01E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS00860 4beff19817580f4ae457b9bb9f75aa3c 83 Gene3D G3DSA:1.10.260.40 7 83 1.8E-17 T 29-03-2018 CSW12_RS00860 4beff19817580f4ae457b9bb9f75aa3c 83 SMART SM00530 23 78 2.3E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS00860 4beff19817580f4ae457b9bb9f75aa3c 83 Pfam PF01381 Helix-turn-helix 24 78 3.3E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS24315 41605fde073a71b1472006ae3cec448c 83 Pfam PF08958 Domain of unknown function (DUF1871) 6 82 2.0E-37 T 29-03-2018 IPR015053 Protein of unknown function DUF1871 CSW12_RS24315 41605fde073a71b1472006ae3cec448c 83 SUPERFAMILY SSF116922 3 78 2.09E-27 T 29-03-2018 IPR023162 Apc36109-like domain CSW12_RS24315 41605fde073a71b1472006ae3cec448c 83 Gene3D G3DSA:1.10.340.20 2 76 6.5E-19 T 29-03-2018 CSW12_RS24315 41605fde073a71b1472006ae3cec448c 83 ProDom PD062625 YUGE 1 83 6.0E-43 T 29-03-2018 IPR015053 Protein of unknown function DUF1871 CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 SUPERFAMILY SSF53850 32 521 4.21E-128 T 29-03-2018 CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 Gene3D G3DSA:3.10.105.10 304 506 4.2E-52 T 29-03-2018 CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 PIRSF PIRSF002741 1 528 3.2E-115 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 84 106 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 Gene3D G3DSA:3.90.76.10 51 172 7.2E-33 T 29-03-2018 CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 457 1.2E-83 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS28400 e68c29f58b6ce38d8241ba9147378274 536 Gene3D G3DSA:3.40.190.10 173 303 5.1E-36 T 29-03-2018 CSW12_RS00155 622e79e3ed32d2ac1deccc5c605df1a1 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 9.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS00155 622e79e3ed32d2ac1deccc5c605df1a1 221 Gene3D G3DSA:1.10.3720.10 6 220 1.1E-34 T 29-03-2018 CSW12_RS00155 622e79e3ed32d2ac1deccc5c605df1a1 221 SUPERFAMILY SSF161098 9 205 4.58E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05830 34cc15cfefd60069af62e60531ca3f4f 639 TIGRFAM TIGR03693 ocin_ThiF_like: putative thiazole-containing bacteriocin maturation protein 1 637 0.0 T 29-03-2018 IPR022368 Putative thiazole-containing bacteriocin maturation protein CSW12_RS05830 34cc15cfefd60069af62e60531ca3f4f 639 Gene3D G3DSA:3.40.50.720 95 168 0.17 T 29-03-2018 CSW12_RS05830 34cc15cfefd60069af62e60531ca3f4f 639 Gene3D G3DSA:3.40.50.720 169 333 3.1E-7 T 29-03-2018 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 Pfam PF00857 Isochorismatase family 32 203 8.2E-40 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 SUPERFAMILY SSF52499 1 217 1.11E-62 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 SUPERFAMILY SSF47336 220 293 1.83E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PRINTS PR01398 Isochorismatase signature 112 134 1.3E-45 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PRINTS PR01398 Isochorismatase signature 63 80 1.3E-45 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PRINTS PR01398 Isochorismatase signature 186 203 1.3E-45 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PRINTS PR01398 Isochorismatase signature 80 99 1.3E-45 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PRINTS PR01398 Isochorismatase signature 168 186 1.3E-45 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PRINTS PR01398 Isochorismatase signature 2 14 1.3E-45 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 Gene3D G3DSA:1.10.1200.10 217 296 4.5E-13 T 29-03-2018 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 Gene3D G3DSA:3.40.50.850 1 211 8.4E-47 T 29-03-2018 CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 Pfam PF00550 Phosphopantetheine attachment site 224 287 9.6E-9 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS16175 3085e1a0c68d8a6073235d45ba7a6860 297 PIRSF PIRSF001111 1 297 5.5E-135 T 29-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 SUPERFAMILY SSF53681 112 265 1.96E-40 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 Gene3D G3DSA:3.40.50.1860 117 269 3.0E-43 T 29-03-2018 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 Hamap MF_00258 Glutamate racemase [murI]. 5 257 40.8 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 Gene3D G3DSA:3.40.50.1860 3 116 5.8E-28 T 29-03-2018 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 SUPERFAMILY SSF53681 6 108 9.81E-37 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 216 2.1E-43 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22070 54411a24e32b747eaf5231484a09c438 269 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 255 2.1E-89 T 29-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14870 b3ebe4f02064e15b3156135b22a477d8 112 Pfam PF01638 HxlR-like helix-turn-helix 17 105 1.6E-34 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS14870 b3ebe4f02064e15b3156135b22a477d8 112 Gene3D G3DSA:1.10.10.10 15 110 2.3E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14870 b3ebe4f02064e15b3156135b22a477d8 112 SUPERFAMILY SSF46785 9 107 6.83E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10815 3be192fa10dbfd387d5d5befeac4ef64 178 Gene3D G3DSA:3.40.50.360 1 174 1.6E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS10815 3be192fa10dbfd387d5d5befeac4ef64 178 SUPERFAMILY SSF52218 1 172 2.39E-44 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS10815 3be192fa10dbfd387d5d5befeac4ef64 178 Pfam PF02525 Flavodoxin-like fold 2 168 7.5E-43 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 Gene3D G3DSA:1.20.1250.20 2 189 3.3E-14 T 29-03-2018 CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 Gene3D G3DSA:1.20.1250.20 205 396 1.3E-13 T 29-03-2018 CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 SUPERFAMILY SSF103473 12 394 2.62E-36 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 Pfam PF05977 Transmembrane secretion effector 12 313 4.9E-25 T 29-03-2018 IPR010290 Transmembrane secretion effector CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 PRINTS PR01988 Putative bacilysin exporter bacE signature 169 186 3.3E-12 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 PRINTS PR01988 Putative bacilysin exporter bacE signature 17 39 3.3E-12 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 PRINTS PR01988 Putative bacilysin exporter bacE signature 253 270 3.3E-12 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 PRINTS PR01988 Putative bacilysin exporter bacE signature 142 163 3.3E-12 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS19470 81ece8eb2d214d6682c9002c39fff973 399 PRINTS PR01988 Putative bacilysin exporter bacE signature 80 98 3.3E-12 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS17590 65757b78973c649b0964858e50ad2789 109 Pfam PF01588 Putative tRNA binding domain 12 107 5.8E-16 T 29-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CSW12_RS17590 65757b78973c649b0964858e50ad2789 109 Gene3D G3DSA:2.40.50.140 1 109 6.0E-19 T 29-03-2018 CSW12_RS17590 65757b78973c649b0964858e50ad2789 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 4 108 1.1E-47 T 29-03-2018 IPR008231 Probable chaperone CsaA CSW12_RS17590 65757b78973c649b0964858e50ad2789 109 SUPERFAMILY SSF50249 2 108 3.92E-30 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS17280 e90fd6164d0f942731abb155308e16d5 176 Pfam PF02613 Nitrate reductase delta subunit 41 147 4.9E-7 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CSW12_RS17280 e90fd6164d0f942731abb155308e16d5 176 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 13 163 4.0E-40 T 29-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CSW12_RS17280 e90fd6164d0f942731abb155308e16d5 176 Gene3D G3DSA:1.10.3480.10 1 170 5.0E-22 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CSW12_RS17280 e90fd6164d0f942731abb155308e16d5 176 SUPERFAMILY SSF89155 9 168 2.35E-22 T 29-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Gene3D G3DSA:3.30.1390.30 166 223 1.7E-18 T 29-03-2018 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Pfam PF03717 Penicillin-binding Protein dimerisation domain 144 311 9.5E-34 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Gene3D G3DSA:3.40.710.10 321 655 2.4E-59 T 29-03-2018 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 SUPERFAMILY SSF56601 326 654 2.44E-76 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 25 136 6.4E-28 T 29-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 SUPERFAMILY SSF54427 27 135 1.84E-30 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 SUPERFAMILY SSF56519 139 325 6.15E-40 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Gene3D G3DSA:3.10.450.100 22 132 2.3E-33 T 29-03-2018 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Gene3D G3DSA:3.90.1310.10 224 320 5.2E-25 T 29-03-2018 CSW12_RS15110 3b7e90fd8e98fbd857b52c1806548b84 655 Pfam PF00905 Penicillin binding protein transpeptidase domain 345 652 5.8E-62 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS07275 1e2066b8744aea911acff4dcc706b525 362 Pfam PF13346 ABC-2 family transporter protein 58 194 1.7E-7 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CSW12_RS02035 9ee6ab600d2e9ee55c9a9b9b261b274d 131 Gene3D G3DSA:3.40.1650.10 8 128 8.1E-40 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CSW12_RS02035 9ee6ab600d2e9ee55c9a9b9b261b274d 131 Pfam PF05025 RbsD / FucU transport protein family 1 130 5.0E-48 T 29-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CSW12_RS02035 9ee6ab600d2e9ee55c9a9b9b261b274d 131 SUPERFAMILY SSF102546 1 131 3.66E-45 T 29-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CSW12_RS02035 9ee6ab600d2e9ee55c9a9b9b261b274d 131 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 131 32.699 T 29-03-2018 IPR023064 D-ribose pyranase GO:0016872 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 SUPERFAMILY SSF46609 99 183 1.03E-31 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 106 117 2.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 257 269 2.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 219 227 2.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 166 179 2.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 PRINTS PR01703 Manganese superoxide dismutase signature 127 140 2.0E-21 T 29-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 259 266 - T 29-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 Gene3D G3DSA:1.10.287.990 120 183 5.1E-19 T 29-03-2018 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 SUPERFAMILY SSF54719 182 296 9.95E-42 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 190 292 1.5E-35 T 29-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS06930 e8308456398a62189d46a26bb9ba47d3 304 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 103 183 2.6E-28 T 29-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CSW12_RS24935 044d6afb1dddc36a69fcd840b2c7726e 237 Pfam PF11368 Protein of unknown function (DUF3169) 46 230 2.4E-13 T 29-03-2018 IPR021509 Protein of unknown function DUF3169 CSW12_RS15405 dfbec835e49a24d400266b5c79949a8a 466 SUPERFAMILY SSF58100 32 367 6.54E-96 T 29-03-2018 CSW12_RS15405 dfbec835e49a24d400266b5c79949a8a 466 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 46 223 7.1E-58 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS15405 dfbec835e49a24d400266b5c79949a8a 466 Gene3D G3DSA:1.20.1170.10 37 373 3.4E-39 T 29-03-2018 CSW12_RS06915 d336143bc516f968cd059122ccce46ab 859 Gene3D G3DSA:3.40.630.30 648 829 1.1E-16 T 29-03-2018 CSW12_RS06915 d336143bc516f968cd059122ccce46ab 859 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 200 302 2.6E-16 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CSW12_RS06915 d336143bc516f968cd059122ccce46ab 859 SUPERFAMILY SSF55729 656 833 1.36E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06915 d336143bc516f968cd059122ccce46ab 859 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 545 836 1.6E-93 T 29-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CSW12_RS06915 d336143bc516f968cd059122ccce46ab 859 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 297 1.8E-17 T 29-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:3.10.600.10 466 532 3.0E-19 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 347 454 3.2E-33 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:3.10.600.10 993 1063 7.0E-20 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SUPERFAMILY SSF89000 835 1012 3.77E-60 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 159 173 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:1.10.10.60 946 992 2.7E-20 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 121 327 1.1E-79 T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SMART SM00878 347 454 7.3E-52 T 29-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 PIRSF PIRSF001594 2 1148 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:2.40.50.100 1076 1148 5.6E-21 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SUPERFAMILY SSF52440 4 118 4.82E-44 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SUPERFAMILY SSF56059 89 332 2.47E-68 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 9 1146 0.0 T 29-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:3.40.50.20 6 129 1.2E-50 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:3.30.1490.20 130 214 2.0E-20 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Pfam PF02436 Conserved carboxylase domain 830 1030 1.6E-77 T 29-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:3.30.470.20 215 462 4.0E-92 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 29-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SUPERFAMILY SSF51246 342 460 1.94E-37 T 29-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SUPERFAMILY SSF51569 527 838 4.76E-86 T 29-03-2018 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 SUPERFAMILY SSF51230 1072 1146 8.64E-23 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 7 115 2.3E-42 T 29-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Pfam PF00682 HMGL-like 535 807 1.2E-27 T 29-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Pfam PF00364 Biotin-requiring enzyme 1080 1146 3.0E-19 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS08015 c060d6a13cf492f558efd8a929822346 1148 Gene3D G3DSA:3.20.20.70 533 833 8.6E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS31050 3934a66465d080b6bcdf74af48e67db5 220 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 182 219 3.6E-12 T 29-03-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CSW12_RS31050 3934a66465d080b6bcdf74af48e67db5 220 SUPERFAMILY SSF52980 55 165 7.51E-23 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS31050 3934a66465d080b6bcdf74af48e67db5 220 Pfam PF04471 Restriction endonuclease 51 161 1.3E-28 T 29-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CSW12_RS31050 3934a66465d080b6bcdf74af48e67db5 220 Gene3D G3DSA:3.30.65.10 168 220 7.6E-13 T 29-03-2018 CSW12_RS31050 3934a66465d080b6bcdf74af48e67db5 220 Gene3D G3DSA:3.40.1350.10 41 167 1.2E-23 T 29-03-2018 CSW12_RS31050 3934a66465d080b6bcdf74af48e67db5 220 SUPERFAMILY SSF57783 169 219 4.76E-7 T 29-03-2018 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 SUPERFAMILY SSF52954 354 456 1.36E-33 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Pfam PF03129 Anticodon binding domain 367 454 1.0E-22 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 163 338 2.7E-9 T 29-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 3 241 4.6E-92 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 1 457 53.009 T 29-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 SUPERFAMILY SSF55681 2 370 2.49E-124 T 29-03-2018 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Gene3D G3DSA:3.40.50.800 354 457 1.2E-27 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Gene3D G3DSA:3.30.930.10 1 101 3.1E-20 T 29-03-2018 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Gene3D G3DSA:3.30.930.10 119 232 7.4E-34 T 29-03-2018 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 Gene3D G3DSA:3.30.930.10 233 353 1.1E-42 T 29-03-2018 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 402 421 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 146 158 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 199 216 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 323 335 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 167 184 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 23 37 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS24360 eaa3e0e308ff9c84f88f49a9cf36297c 458 PRINTS PR01043 Glycyl-tRNA synthetase signature 216 226 5.9E-53 T 29-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS25700 b0b3e8561aa2ff2da7cf8fd7e6d9540c 104 Gene3D G3DSA:1.10.10.10 15 104 1.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25700 b0b3e8561aa2ff2da7cf8fd7e6d9540c 104 SUPERFAMILY SSF46785 3 103 6.12E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25700 b0b3e8561aa2ff2da7cf8fd7e6d9540c 104 Pfam PF01638 HxlR-like helix-turn-helix 17 103 1.5E-31 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS11985 150f054504553396d194c2718534c9d7 134 SUPERFAMILY SSF52788 4 129 1.24E-44 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS11985 150f054504553396d194c2718534c9d7 134 Hamap MF_01624 Protein ArsC [arsC]. 2 132 44.07 T 29-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CSW12_RS11985 150f054504553396d194c2718534c9d7 134 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 129 1.3E-24 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS11985 150f054504553396d194c2718534c9d7 134 SMART SM00226 5 132 4.3E-56 T 29-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CSW12_RS11985 150f054504553396d194c2718534c9d7 134 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 129 1.2E-64 T 29-03-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 CSW12_RS11985 150f054504553396d194c2718534c9d7 134 Gene3D G3DSA:3.40.50.2300 1 132 4.9E-41 T 29-03-2018 CSW12_RS27890 e6ab5e741ef3d6bf493f2c1bb1cc4b1f 170 Pfam PF05991 YacP-like NYN domain 5 167 1.4E-53 T 29-03-2018 IPR010298 Protein of unknown function DUF901 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 Pfam PF01632 Ribosomal protein L35 2 62 2.5E-25 T 29-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 SUPERFAMILY SSF143034 2 62 3.53E-22 T 29-03-2018 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 29-03-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 5.1E-26 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.829 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 4.6E-21 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 4.6E-21 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CSW12_RS22485 f2c6294f06ff53f6066df6d707107931 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 4.6E-21 T 29-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 813 877 3.61E-9 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 1177 1241 1.65E-8 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 432 528 1.0E-25 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 885 976 3.9E-27 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 529 614 2.2E-22 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 1255 1378 8.9E-26 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 615 704 3.8E-25 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 1071 1158 1.3E-22 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 795 884 2.8E-24 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 1159 1254 2.3E-23 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 977 1070 6.2E-28 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.810 705 794 6.1E-24 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 1269 1333 5.1E-9 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 53 334 6.8E-22 T 29-03-2018 IPR026588 Choice-of-anchor A domain CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 902 968 8.63E-10 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 998 1069 1.37E-8 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 352 422 1.1E-9 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 1085 1154 1.88E-8 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 721 790 3.65E-8 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 Gene3D G3DSA:2.60.40.10 339 431 2.2E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 448 516 2.35E-9 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 632 696 1.88E-9 T 29-03-2018 CSW12_RS03710 65d416bfa42870aa51c06800c667811a 1463 SUPERFAMILY SSF49478 540 611 1.57E-8 T 29-03-2018 CSW12_RS29960 584bcdb5c83f062c98407f6f4c1eb9f3 293 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 289 7.3E-63 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS29960 584bcdb5c83f062c98407f6f4c1eb9f3 293 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 245 1.4E-60 T 29-03-2018 CSW12_RS29960 584bcdb5c83f062c98407f6f4c1eb9f3 293 Gene3D G3DSA:1.10.10.60 242 293 5.0E-11 T 29-03-2018 CSW12_RS18190 d8b44b7839acddae4e60b8f6a1aac511 333 Gene3D G3DSA:1.10.3470.10 27 306 1.7E-31 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS18190 d8b44b7839acddae4e60b8f6a1aac511 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 300 1.3E-33 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS09315 49b5923d3dd53ce9ef9d1425892e433f 312 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 48 298 4.9E-66 T 29-03-2018 CSW12_RS09315 49b5923d3dd53ce9ef9d1425892e433f 312 Gene3D G3DSA:3.40.190.10 147 295 6.3E-38 T 29-03-2018 CSW12_RS09315 49b5923d3dd53ce9ef9d1425892e433f 312 Gene3D G3DSA:3.40.190.10 31 144 1.3E-9 T 29-03-2018 CSW12_RS09315 49b5923d3dd53ce9ef9d1425892e433f 312 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 6 271 1.3E-71 T 29-03-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CSW12_RS09315 49b5923d3dd53ce9ef9d1425892e433f 312 SMART SM00062 43 289 8.3E-4 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS09315 49b5923d3dd53ce9ef9d1425892e433f 312 SUPERFAMILY SSF53850 41 307 4.13E-51 T 29-03-2018 CSW12_RS24380 ece365489351b970ed097dc4531b659c 295 Gene3D G3DSA:3.90.550.10 1 277 7.9E-64 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24380 ece365489351b970ed097dc4531b659c 295 SUPERFAMILY SSF53448 4 275 3.76E-70 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24380 ece365489351b970ed097dc4531b659c 295 Pfam PF00483 Nucleotidyl transferase 6 258 1.7E-35 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS24380 ece365489351b970ed097dc4531b659c 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 1.7E-122 T 29-03-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 Pfam PF00579 tRNA synthetases class I (W and Y) 5 281 1.4E-55 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 Gene3D G3DSA:3.40.50.620 2 208 4.9E-60 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 SUPERFAMILY SSF52374 5 328 4.1E-81 T 29-03-2018 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 6.4E-12 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 6.4E-12 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 6.4E-12 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 Gene3D G3DSA:1.10.240.10 209 324 1.4E-24 T 29-03-2018 CSW12_RS11185 ebac862b1dbe689144d82da2dbb675c8 332 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 328 1.6E-81 T 29-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CSW12_RS21985 2290dd23db01d014d4093d8f06874adc 198 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.006 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CSW12_RS21985 2290dd23db01d014d4093d8f06874adc 198 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 6.4E-70 T 29-03-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CSW12_RS21985 2290dd23db01d014d4093d8f06874adc 198 Gene3D G3DSA:3.40.50.300 3 198 3.8E-30 T 29-03-2018 CSW12_RS21985 2290dd23db01d014d4093d8f06874adc 198 Pfam PF01926 50S ribosome-binding GTPase 25 143 3.6E-21 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21985 2290dd23db01d014d4093d8f06874adc 198 SUPERFAMILY SSF52540 16 193 4.83E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13705 2bb354f52b4b31e81a41d5f5cec92c01 144 SUPERFAMILY SSF55729 9 143 4.05E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13705 2bb354f52b4b31e81a41d5f5cec92c01 144 Pfam PF13673 Acetyltransferase (GNAT) domain 41 143 6.4E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13705 2bb354f52b4b31e81a41d5f5cec92c01 144 Gene3D G3DSA:3.40.630.30 2 144 1.2E-30 T 29-03-2018 CSW12_RS21580 59e776888745270c236740b00aa3b015 114 Pfam PF14470 Bacterial PH domain 12 110 7.7E-12 T 29-03-2018 CSW12_RS05705 842eecee9d105c0f99fba139c58828e6 492 Pfam PF00474 Sodium:solute symporter family 35 433 5.8E-110 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS05705 842eecee9d105c0f99fba139c58828e6 492 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 487 2.8E-221 T 29-03-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 CSW12_RS05705 842eecee9d105c0f99fba139c58828e6 492 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 433 3.2E-99 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS05705 842eecee9d105c0f99fba139c58828e6 492 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 29-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 243 4.0E-23 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 SUPERFAMILY SSF56219 1 251 8.9E-81 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 250 1.3E-101 T 29-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 211 222 - T 29-03-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 250 3.7E-100 T 29-03-2018 CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 29-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CSW12_RS09095 2e75b9312ad4860c668b4f8763a10909 252 Gene3D G3DSA:3.60.10.10 1 252 2.7E-56 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 398 407 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Pfam PF00067 Cytochrome P450 17 449 2.5E-86 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Pfam PF00175 Oxidoreductase NAD-binding domain 916 1026 8.3E-15 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Pfam PF00258 Flavodoxin 498 630 6.6E-27 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Gene3D G3DSA:3.40.50.360 468 657 1.7E-43 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00369 Flavodoxin signature 575 585 5.1E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00369 Flavodoxin signature 600 619 5.1E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00369 Flavodoxin signature 497 510 5.1E-9 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 878 887 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 944 953 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1011 1019 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 843 850 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 988 1004 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 957 968 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 709 719 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 915 934 1.8E-30 T 29-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 SUPERFAMILY SSF48264 5 457 1.31E-109 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 SUPERFAMILY SSF52218 492 648 2.3E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Gene3D G3DSA:1.10.630.10 4 467 1.8E-115 T 29-03-2018 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Gene3D G3DSA:3.40.50.80 912 1063 9.2E-34 T 29-03-2018 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Gene3D G3DSA:2.40.30.10 669 895 2.2E-47 T 29-03-2018 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 Pfam PF00667 FAD binding domain 677 883 2.0E-40 T 29-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 PIRSF PIRSF000209 2 1065 0.0 T 29-03-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 SUPERFAMILY SSF52343 903 1062 9.95E-46 T 29-03-2018 CSW12_RS11720 e3ad30666103d972fefd45d0e47b15b0 1065 SUPERFAMILY SSF63380 676 899 4.86E-63 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CSW12_RS25600 8d69562f035b51430e4fc4ce28721f0f 400 SUPERFAMILY SSF50156 306 390 4.26E-12 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS25600 8d69562f035b51430e4fc4ce28721f0f 400 Gene3D G3DSA:2.30.42.10 279 377 1.7E-7 T 29-03-2018 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 851 884 6.9E-5 T 29-03-2018 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Gene3D G3DSA:2.60.40.10 580 663 1.3E-16 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Gene3D G3DSA:2.60.40.10 746 829 4.2E-15 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Gene3D G3DSA:1.10.390.10 406 569 1.5E-40 T 29-03-2018 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 248 401 5.8E-31 T 29-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 392 408 1.1E-12 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 483 499 1.1E-12 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 413 424 1.1E-12 T 29-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Gene3D G3DSA:2.60.40.10 666 742 4.6E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF00746 LPXTG cell wall anchor motif 850 884 2.2E-4 T 29-03-2018 IPR019948 Gram-positive LPXTG cell wall anchor CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 404 567 3.6E-49 T 29-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 SUPERFAMILY SSF55486 247 565 7.33E-67 T 29-03-2018 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF16403 Domain of unknown function (DUF5011) 591 656 2.6E-14 T 29-03-2018 IPR032179 Domain of unknown function DUF5011 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF16403 Domain of unknown function (DUF5011) 676 739 7.3E-16 T 29-03-2018 IPR032179 Domain of unknown function DUF5011 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF16403 Domain of unknown function (DUF5011) 756 815 1.8E-12 T 29-03-2018 IPR032179 Domain of unknown function DUF5011 CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 85 133 7.1E-12 T 29-03-2018 IPR011096 FTP domain CSW12_RS14920 1861e1d493e9068306033b3e2cec2727 887 Gene3D G3DSA:3.10.170.10 208 404 1.3E-32 T 29-03-2018 CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 Pfam PF12857 TOBE-like domain 291 345 5.3E-16 T 29-03-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 Gene3D G3DSA:3.40.50.300 1 242 3.7E-79 T 29-03-2018 CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 Pfam PF00005 ABC transporter 18 164 2.5E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 Gene3D G3DSA:2.40.50.100 277 345 1.3E-6 T 29-03-2018 CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 SUPERFAMILY SSF52540 3 247 8.83E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 SUPERFAMILY SSF50331 239 351 3.64E-14 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 SMART SM00382 27 214 6.8E-21 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS04795 eb3e058e07f4c545db540e201e975e4a 357 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 3.4E-120 T 29-03-2018 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CSW12_RS03165 396088135cceb2e79b51317deb91a1a2 156 SUPERFAMILY SSF52540 19 99 8.43E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03165 396088135cceb2e79b51317deb91a1a2 156 Gene3D G3DSA:3.40.50.300 10 154 1.8E-9 T 29-03-2018 CSW12_RS03165 396088135cceb2e79b51317deb91a1a2 156 Pfam PF13476 AAA domain 21 61 4.6E-7 T 29-03-2018 CSW12_RS08925 a6c463914f2d5af78d1c19c5995f86ac 143 SUPERFAMILY SSF158622 4 123 3.4E-37 T 29-03-2018 IPR023378 YheA/YmcA-like domain CSW12_RS08925 a6c463914f2d5af78d1c19c5995f86ac 143 Gene3D G3DSA:1.20.1500.10 8 116 1.4E-32 T 29-03-2018 IPR023378 YheA/YmcA-like domain CSW12_RS08925 a6c463914f2d5af78d1c19c5995f86ac 143 PIRSF PIRSF021287 1 123 5.8E-53 T 29-03-2018 IPR016783 Biofilm formation YmcA CSW12_RS08925 a6c463914f2d5af78d1c19c5995f86ac 143 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 2.4E-25 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 Gene3D G3DSA:3.30.390.30 348 470 1.9E-39 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 Gene3D G3DSA:3.50.50.60 8 164 2.4E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 SUPERFAMILY SSF55424 346 468 9.28E-40 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 4.0E-75 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 457 7.5E-35 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 SUPERFAMILY SSF51905 8 340 2.24E-67 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 9.9E-43 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 9.9E-43 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 9.9E-43 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 9.9E-43 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 9.9E-43 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 6.5E-76 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 2.2E-176 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 PIRSF PIRSF000350 3 459 4.8E-100 T 29-03-2018 CSW12_RS07895 b1ab16fcf5619a2c44df317c747636a1 470 Gene3D G3DSA:3.40.50.720 165 342 5.3E-39 T 29-03-2018 CSW12_RS19300 c8e5bdd129445bbc7db2ae900a871742 161 Gene3D G3DSA:1.10.220.30 14 161 3.3E-7 T 29-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CSW12_RS12990 b9dc4f8c8abda178b2bfbc79c06b3cc4 227 Pfam PF08713 DNA alkylation repair enzyme 6 189 4.9E-25 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CSW12_RS12990 b9dc4f8c8abda178b2bfbc79c06b3cc4 227 Gene3D G3DSA:1.20.1660.10 4 115 2.7E-6 T 29-03-2018 CSW12_RS12990 b9dc4f8c8abda178b2bfbc79c06b3cc4 227 SUPERFAMILY SSF48371 1 223 9.5E-65 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS12990 b9dc4f8c8abda178b2bfbc79c06b3cc4 227 Gene3D G3DSA:1.25.40.290 116 225 1.8E-5 T 29-03-2018 CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 Gene3D G3DSA:1.20.1250.20 377 475 1.7E-4 T 29-03-2018 CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 3 363 3.4E-38 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 Pfam PF01514 Secretory protein of YscJ/FliF family 20 211 1.7E-42 T 29-03-2018 IPR006182 Secretory protein YscJ/FliF CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 Pfam PF08345 Flagellar M-ring protein C-terminal 247 407 2.3E-19 T 29-03-2018 IPR013556 Flagellar M-ring C-terminal CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 PRINTS PR01009 Flagellar M-ring protein signature 187 205 1.4E-7 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 PRINTS PR01009 Flagellar M-ring protein signature 337 361 1.4E-7 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CSW12_RS19345 63bd159d714ac860b51fde09adac8185 524 PRINTS PR01009 Flagellar M-ring protein signature 143 157 1.4E-7 T 29-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 Gene3D G3DSA:1.10.3860.10 1 408 3.5E-133 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 4.0E-126 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 SUPERFAMILY SSF118215 6 402 5.23E-129 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS06745 335fd2f559085caa3a11b58ec2512f48 424 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 3.1E-36 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS11505 bb59e013ff74ee6e725d1d3c8be140a8 243 SUPERFAMILY SSF55166 76 226 9.94E-32 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS11505 bb59e013ff74ee6e725d1d3c8be140a8 243 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 78 219 5.7E-45 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CSW12_RS11505 bb59e013ff74ee6e725d1d3c8be140a8 243 Gene3D G3DSA:3.30.1380.10 55 230 3.2E-37 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 Gene3D G3DSA:1.10.3120.10 213 399 1.8E-57 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 TIGRFAM TIGR00115 tig: trigger factor 14 421 9.0E-145 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 SUPERFAMILY SSF102735 1 128 2.49E-38 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 2.9E-43 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 3.7E-49 T 29-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 Hamap MF_00303 Trigger factor [tig]. 1 425 23.972 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 238 4.5E-14 T 29-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 Gene3D G3DSA:3.30.70.1050 1 119 1.8E-36 T 29-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 SUPERFAMILY SSF109998 250 424 1.57E-45 T 29-03-2018 IPR027304 Trigger factor/SurA domain CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 SUPERFAMILY SSF54534 89 243 8.64E-38 T 29-03-2018 CSW12_RS22005 3a12727b7efe5545f2a78ab54749cece 425 PIRSF PIRSF003095 1 425 9.3E-141 T 29-03-2018 IPR005215 Trigger factor GO:0015031 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF49493 113 171 2.09E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF49493 217 259 2.09E-19 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 41 61 2.8E-31 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 61 80 2.8E-31 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 25 40 2.8E-31 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 PRINTS PR00625 DnaJ domain signature 7 25 2.8E-31 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:2.10.230.10 143 200 6.1E-17 T 29-03-2018 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 1.0E-142 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF57938 133 214 1.31E-18 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF49493 261 347 4.32E-25 T 29-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Pfam PF00226 DnaJ domain 5 66 1.0E-27 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:2.60.260.20 201 257 1.1E-12 T 29-03-2018 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:1.10.287.110 1 113 6.1E-38 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Pfam PF00684 DnaJ central domain 146 210 6.1E-14 T 29-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Gene3D G3DSA:2.60.260.20 258 367 3.3E-31 T 29-03-2018 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 SMART SM00271 4 61 2.7E-31 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 29-03-2018 IPR018253 DnaJ domain, conserved site CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 SUPERFAMILY SSF46565 1 104 8.9E-38 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 367 41.629 T 29-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CSW12_RS21185 9861a44e442a2309c9b3e8b55a4801ce 371 Pfam PF01556 DnaJ C terminal domain 119 336 1.5E-43 T 29-03-2018 IPR002939 Chaperone DnaJ, C-terminal CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.4E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 SUPERFAMILY SSF46785 7 76 1.44E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 4.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 4.9E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 SMART SM00866 93 232 1.1E-26 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 Gene3D G3DSA:1.10.10.10 2 74 8.4E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 Gene3D G3DSA:3.40.1410.10 90 237 9.3E-28 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 SMART SM00345 13 72 2.2E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 SUPERFAMILY SSF64288 60 237 6.57E-40 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS10920 a37fa59c8a867f2956735c1e4dd7dcdc 245 Pfam PF07702 UTRA domain 95 231 1.6E-27 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 4.4E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 4.4E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 4.4E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 4.4E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 4.4E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 4.4E-27 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 2 436 26.667 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 Gene3D G3DSA:3.40.50.10490 1 60 1.1E-9 T 29-03-2018 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 Gene3D G3DSA:3.40.50.10490 61 208 3.6E-45 T 29-03-2018 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 29-03-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 Gene3D G3DSA:3.40.50.10490 209 435 1.1E-76 T 29-03-2018 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 SUPERFAMILY SSF53697 6 448 1.31E-143 T 29-03-2018 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 Pfam PF00342 Phosphoglucose isomerase 77 296 1.1E-17 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24275 6de7db12b4fefdd3de441a05caa41973 450 Pfam PF00342 Phosphoglucose isomerase 331 426 9.7E-5 T 29-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 Gene3D G3DSA:3.40.50.720 89 228 2.5E-36 T 29-03-2018 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 PRINTS PR00086 L-lactate dehydrogenase signature 225 243 4.1E-44 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 PRINTS PR00086 L-lactate dehydrogenase signature 255 268 4.1E-44 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 PRINTS PR00086 L-lactate dehydrogenase signature 114 138 4.1E-44 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 PRINTS PR00086 L-lactate dehydrogenase signature 89 113 4.1E-44 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 PRINTS PR00086 L-lactate dehydrogenase signature 201 221 4.1E-44 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 89 227 5.9E-43 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 230 394 1.3E-25 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 Gene3D G3DSA:3.90.110.10 229 397 3.8E-45 T 29-03-2018 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 92 390 2.8E-119 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 87 397 44.662 T 29-03-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 SUPERFAMILY SSF51735 72 227 1.55E-53 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 257 263 - T 29-03-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 CSW12_RS24790 25aec6054366b92f51d44753c7368bf9 398 SUPERFAMILY SSF56327 228 396 6.14E-55 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 SUPERFAMILY SSF56796 7 356 1.15E-97 T 29-03-2018 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 Pfam PF01761 3-dehydroquinate synthase 68 323 1.2E-95 T 29-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 355 38.02 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 PIRSF PIRSF001455 3 360 3.9E-101 T 29-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 Gene3D G3DSA:1.20.1090.10 173 359 4.8E-55 T 29-03-2018 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 Gene3D G3DSA:3.40.50.1970 2 172 4.5E-45 T 29-03-2018 CSW12_RS20015 ccbc406c1306a9c175fdd3a3841648ca 361 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 349 4.7E-110 T 29-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CSW12_RS08495 244adbc47bddb5a7449f4ee1654af960 558 Pfam PF02734 DAK2 domain 36 200 2.9E-40 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS08495 244adbc47bddb5a7449f4ee1654af960 558 Pfam PF13684 Dihydroxyacetone kinase family 240 558 2.1E-123 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CSW12_RS08495 244adbc47bddb5a7449f4ee1654af960 558 SMART SM01120 36 201 1.8E-68 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS08495 244adbc47bddb5a7449f4ee1654af960 558 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 558 1.9E-210 T 29-03-2018 IPR019986 DAK2 domain-containing protein YloV CSW12_RS08495 244adbc47bddb5a7449f4ee1654af960 558 SMART SM01121 240 558 2.2E-187 T 29-03-2018 IPR033470 Uncharacterised protein, DhaK domain CSW12_RS08495 244adbc47bddb5a7449f4ee1654af960 558 SUPERFAMILY SSF101473 2 200 1.57E-44 T 29-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS07140 2ae58e676e43145064ea89ca81224875 409 Pfam PF01548 Transposase 5 165 1.0E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS07140 2ae58e676e43145064ea89ca81224875 409 Gene3D G3DSA:1.10.150.280 257 370 0.001 T 29-03-2018 CSW12_RS07140 2ae58e676e43145064ea89ca81224875 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 280 365 6.3E-25 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS11545 2ae58e676e43145064ea89ca81224875 409 Pfam PF01548 Transposase 5 165 1.0E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS11545 2ae58e676e43145064ea89ca81224875 409 Gene3D G3DSA:1.10.150.280 257 370 0.001 T 29-03-2018 CSW12_RS11545 2ae58e676e43145064ea89ca81224875 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 280 365 6.3E-25 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS20070 2ae58e676e43145064ea89ca81224875 409 Pfam PF01548 Transposase 5 165 1.0E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS20070 2ae58e676e43145064ea89ca81224875 409 Gene3D G3DSA:1.10.150.280 257 370 0.001 T 29-03-2018 CSW12_RS20070 2ae58e676e43145064ea89ca81224875 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 280 365 6.3E-25 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS13320 2ae58e676e43145064ea89ca81224875 409 Pfam PF01548 Transposase 5 165 1.0E-35 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS13320 2ae58e676e43145064ea89ca81224875 409 Gene3D G3DSA:1.10.150.280 257 370 0.001 T 29-03-2018 CSW12_RS13320 2ae58e676e43145064ea89ca81224875 409 Pfam PF02371 Transposase IS116/IS110/IS902 family 280 365 6.3E-25 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS28590 9df36788364ebf38756dadda5435dfbe 307 SUPERFAMILY SSF161098 91 285 4.84E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28590 9df36788364ebf38756dadda5435dfbe 307 Gene3D G3DSA:1.10.3720.10 25 295 3.4E-46 T 29-03-2018 CSW12_RS28590 9df36788364ebf38756dadda5435dfbe 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 307 2.7E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28590 9df36788364ebf38756dadda5435dfbe 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 73 2.4E-13 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 Gene3D G3DSA:1.10.3100.10 1 138 2.0E-22 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 Gene3D G3DSA:1.25.40.10 269 323 0.0015 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 Gene3D G3DSA:1.25.40.10 139 254 0.055 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 SUPERFAMILY SSF47413 2 68 1.01E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 Gene3D G3DSA:1.25.40.10 324 391 7.1E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 Pfam PF12844 Helix-turn-helix domain 5 63 1.8E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 SUPERFAMILY SSF48452 162 395 1.11E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS19155 32c76bb6e7b1a9bec8c3773d05f6abf6 404 SMART SM00530 7 61 2.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Gene3D G3DSA:3.30.565.10 350 497 2.7E-40 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 SUPERFAMILY SSF55874 346 495 6.16E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 SUPERFAMILY SSF47384 274 345 2.35E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 SMART SM00387 391 497 1.6E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 286 346 1.5E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Pfam PF02743 Cache domain 83 213 1.2E-13 T 29-03-2018 IPR033479 Double Cache domain 1 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Gene3D G3DSA:1.10.287.130 265 345 2.2E-14 T 29-03-2018 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 SMART SM00388 284 349 1.7E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 442 2.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 456 2.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 494 2.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 475 2.9E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Pfam PF11346 Protein of unknown function (DUF3149) 8 38 2.2E-9 T 29-03-2018 IPR021494 Protein of unknown function DUF3149 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Gene3D G3DSA:3.30.450.20 41 117 1.6E-16 T 29-03-2018 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Gene3D G3DSA:3.30.450.20 152 209 1.2E-10 T 29-03-2018 CSW12_RS06220 c296c6c074899ede87bbace972905b91 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 496 8.5E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16165 66b7cfcef33bf2a48318a50a4da3d926 74 SMART SM00923 3 53 5.1E-29 T 29-03-2018 IPR005153 MbtH-like protein CSW12_RS16165 66b7cfcef33bf2a48318a50a4da3d926 74 Gene3D G3DSA:3.90.820.10 2 68 1.8E-29 T 29-03-2018 CSW12_RS16165 66b7cfcef33bf2a48318a50a4da3d926 74 SUPERFAMILY SSF160582 1 64 1.44E-27 T 29-03-2018 CSW12_RS16165 66b7cfcef33bf2a48318a50a4da3d926 74 Pfam PF03621 MbtH-like protein 1 52 1.2E-26 T 29-03-2018 IPR005153 MbtH-like protein CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 Gene3D G3DSA:3.40.50.300 144 421 2.9E-26 T 29-03-2018 CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 SUPERFAMILY SSF52540 282 438 6.51E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 SUPERFAMILY SSF52540 482 624 6.51E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 SUPERFAMILY SSF52540 157 217 6.51E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 Pfam PF13086 AAA domain 163 374 3.3E-27 T 29-03-2018 CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 Gene3D G3DSA:3.40.50.300 422 617 2.2E-20 T 29-03-2018 CSW12_RS11940 3577ffe699046209bf977ea6c77470ce 759 Pfam PF13087 AAA domain 405 590 1.4E-28 T 29-03-2018 CSW12_RS27880 430952e4987f847c757b58f7d5713081 135 Gene3D G3DSA:1.10.1520.10 2 135 4.4E-21 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS27880 430952e4987f847c757b58f7d5713081 135 SMART SM00535 1 128 0.003 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS27880 430952e4987f847c757b58f7d5713081 135 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 1 127 30.398 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CSW12_RS27880 430952e4987f847c757b58f7d5713081 135 SUPERFAMILY SSF69065 3 126 5.76E-44 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS27880 430952e4987f847c757b58f7d5713081 135 Pfam PF00636 Ribonuclease III domain 11 108 5.4E-15 T 29-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CSW12_RS27880 430952e4987f847c757b58f7d5713081 135 PIRSF PIRSF005520 1 132 8.0E-54 T 29-03-2018 IPR008226 Mini-ribonuclease 3 family CSW12_RS11490 8263c6a1061ef3411753a5000c7588dc 398 Gene3D G3DSA:1.20.1250.20 3 195 7.7E-24 T 29-03-2018 CSW12_RS11490 8263c6a1061ef3411753a5000c7588dc 398 SUPERFAMILY SSF103473 5 381 6.8E-53 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11490 8263c6a1061ef3411753a5000c7588dc 398 Pfam PF07690 Major Facilitator Superfamily 13 236 3.3E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS11490 8263c6a1061ef3411753a5000c7588dc 398 Gene3D G3DSA:1.20.1250.20 196 394 2.4E-25 T 29-03-2018 CSW12_RS23310 f9253039ff1ebd6820feea21f41098c7 337 Pfam PF00899 ThiF family 5 240 2.5E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS23310 f9253039ff1ebd6820feea21f41098c7 337 SUPERFAMILY SSF69572 3 329 7.85E-88 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS23310 f9253039ff1ebd6820feea21f41098c7 337 Gene3D G3DSA:3.40.50.720 1 244 1.4E-64 T 29-03-2018 CSW12_RS18500 98c8f0cb9c5010da4f5befc45480f45f 94 Pfam PF13780 Domain of unknown function (DUF4176) 9 82 6.2E-26 T 29-03-2018 IPR025233 Protein of unknown function DUF4176 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Pfam PF01391 Collagen triple helix repeat (20 copies) 191 248 9.2E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Pfam PF01391 Collagen triple helix repeat (20 copies) 296 352 1.5E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Pfam PF01391 Collagen triple helix repeat (20 copies) 254 312 6.9E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Pfam PF01391 Collagen triple helix repeat (20 copies) 158 212 7.9E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Gene3D G3DSA:2.160.20.50 245 306 7.1E-9 T 29-03-2018 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Gene3D G3DSA:2.160.20.50 307 352 1.3E-7 T 29-03-2018 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Gene3D G3DSA:2.160.20.50 184 244 5.0E-11 T 29-03-2018 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 SUPERFAMILY SSF48371 43 147 4.54E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Gene3D G3DSA:2.130.10.10 462 537 9.7E-27 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Gene3D G3DSA:2.130.10.10 538 653 7.2E-29 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Gene3D G3DSA:2.130.10.10 353 461 1.2E-26 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Pfam PF10282 Lactonase, 7-bladed beta-propeller 514 635 3.6E-9 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 Pfam PF10282 Lactonase, 7-bladed beta-propeller 392 504 3.2E-8 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 SUPERFAMILY SSF50974 369 650 9.94E-80 T 29-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 443 484 8.3E-17 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 485 525 5.0E-15 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 401 442 5.7E-17 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 370 400 1.7E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 528 565 8.4E-15 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 611 650 9.0E-16 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS14500 bf5bcdb58b63217ba611a073de4d2c4d 656 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 569 609 8.1E-13 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02690 2afdcf288810af065a529823b5ae3b90 79 Pfam PF13214 Protein of unknown function (DUF4022) 1 77 1.2E-48 T 29-03-2018 IPR025095 Protein of unknown function DUF4022 CSW12_RS24330 e9a87a44349ff2fc6772e8b4352641d9 127 SUPERFAMILY SSF141251 4 126 5.62E-53 T 29-03-2018 CSW12_RS24330 e9a87a44349ff2fc6772e8b4352641d9 127 SMART SM01298 15 127 5.6E-75 T 29-03-2018 IPR014916 Kinase associated protein B CSW12_RS24330 e9a87a44349ff2fc6772e8b4352641d9 127 Pfam PF08810 Kinase associated protein B 15 126 5.9E-50 T 29-03-2018 IPR014916 Kinase associated protein B CSW12_RS24650 44d2f0fcfbbac613bc2616372c5ca9d3 257 Pfam PF10086 Putative membrane peptidase family (DUF2324) 17 233 2.1E-78 T 29-03-2018 IPR011397 Uncharacterised conserved protein UCP033101 CSW12_RS24650 44d2f0fcfbbac613bc2616372c5ca9d3 257 PIRSF PIRSF033101 1 257 7.1E-107 T 29-03-2018 IPR011397 Uncharacterised conserved protein UCP033101 CSW12_RS07135 18484544b9637597c537162430025c26 86 Pfam PF14069 Stage VI sporulation protein F 9 80 7.8E-30 T 29-03-2018 IPR025942 Stage VI sporulation protein F CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 SUPERFAMILY SSF52172 2 129 5.83E-44 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 Pfam PF00072 Response regulator receiver domain 5 114 7.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 SUPERFAMILY SSF46894 134 233 8.22E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 232 3.6E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 SMART SM00448 3 114 4.6E-48 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 Gene3D G3DSA:1.10.10.10 130 239 3.1E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 Gene3D G3DSA:3.40.50.2300 2 129 6.9E-39 T 29-03-2018 CSW12_RS22565 51d1a19cfbe45d77319eb3cf03eb2df2 239 SMART SM00862 156 232 2.8E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS28125 7807bf09e7b6d20c8768ebdf331c7865 120 SUPERFAMILY SSF64263 2 120 1.57E-44 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28125 7807bf09e7b6d20c8768ebdf331c7865 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.431 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28125 7807bf09e7b6d20c8768ebdf331c7865 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 120 2.7E-48 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28125 7807bf09e7b6d20c8768ebdf331c7865 120 Pfam PF01196 Ribosomal protein L17 16 120 1.9E-39 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28125 7807bf09e7b6d20c8768ebdf331c7865 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28125 7807bf09e7b6d20c8768ebdf331c7865 120 Gene3D G3DSA:3.90.1030.10 1 120 3.6E-48 T 29-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS25615 853568710c4d7892d839fb77b3c2a71b 228 SUPERFAMILY SSF52540 1 218 6.36E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25615 853568710c4d7892d839fb77b3c2a71b 228 SMART SM00382 27 221 1.3E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25615 853568710c4d7892d839fb77b3c2a71b 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25615 853568710c4d7892d839fb77b3c2a71b 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 213 1.6E-87 T 29-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CSW12_RS25615 853568710c4d7892d839fb77b3c2a71b 228 Gene3D G3DSA:3.40.50.300 1 221 1.7E-64 T 29-03-2018 CSW12_RS25615 853568710c4d7892d839fb77b3c2a71b 228 Pfam PF00005 ABC transporter 20 165 1.4E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS07390 cbafd4081b727c2a70148a16941fee9b 247 Pfam PF02616 Segregation and condensation protein ScpA 20 241 1.6E-57 T 29-03-2018 IPR003768 Segregation and condensation protein A CSW12_RS07390 cbafd4081b727c2a70148a16941fee9b 247 Hamap MF_01805 Segregation and condensation protein A [scpA]. 3 244 27.219 T 29-03-2018 IPR003768 Segregation and condensation protein A CSW12_RS07390 cbafd4081b727c2a70148a16941fee9b 247 Gene3D G3DSA:1.10.10.580 178 242 2.9E-13 T 29-03-2018 CSW12_RS13515 656fd54694a67f7c1aa9dd79afdd2609 313 Pfam PF05544 Proline racemase 10 310 1.2E-28 T 29-03-2018 IPR008794 Proline racemase family CSW12_RS13515 656fd54694a67f7c1aa9dd79afdd2609 313 PIRSF PIRSF029792 1 313 1.4E-83 T 29-03-2018 IPR008794 Proline racemase family CSW12_RS13515 656fd54694a67f7c1aa9dd79afdd2609 313 Gene3D G3DSA:3.10.310.10 3 313 1.5E-25 T 29-03-2018 CSW12_RS13515 656fd54694a67f7c1aa9dd79afdd2609 313 SUPERFAMILY SSF54506 1 310 2.9E-59 T 29-03-2018 CSW12_RS28980 9e3700e775db4dfafd900218d408a561 643 SUPERFAMILY SSF53448 368 611 5.16E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS28980 9e3700e775db4dfafd900218d408a561 643 Gene3D G3DSA:3.90.550.10 369 607 2.7E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS28980 9e3700e775db4dfafd900218d408a561 643 Gene3D G3DSA:3.40.50.2000 150 361 7.2E-28 T 29-03-2018 CSW12_RS28980 9e3700e775db4dfafd900218d408a561 643 Pfam PF00535 Glycosyl transferase family 2 370 484 2.0E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS28980 9e3700e775db4dfafd900218d408a561 643 SUPERFAMILY SSF53756 7 363 9.94E-43 T 29-03-2018 CSW12_RS28980 9e3700e775db4dfafd900218d408a561 643 Pfam PF00534 Glycosyl transferases group 1 180 335 7.8E-15 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS29055 9e3700e775db4dfafd900218d408a561 643 SUPERFAMILY SSF53448 368 611 5.16E-40 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS29055 9e3700e775db4dfafd900218d408a561 643 Gene3D G3DSA:3.90.550.10 369 607 2.7E-32 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS29055 9e3700e775db4dfafd900218d408a561 643 Gene3D G3DSA:3.40.50.2000 150 361 7.2E-28 T 29-03-2018 CSW12_RS29055 9e3700e775db4dfafd900218d408a561 643 Pfam PF00535 Glycosyl transferase family 2 370 484 2.0E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS29055 9e3700e775db4dfafd900218d408a561 643 SUPERFAMILY SSF53756 7 363 9.94E-43 T 29-03-2018 CSW12_RS29055 9e3700e775db4dfafd900218d408a561 643 Pfam PF00534 Glycosyl transferases group 1 180 335 7.8E-15 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 Gene3D G3DSA:2.40.100.10 3 145 8.9E-49 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 29-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 10 138 9.2E-40 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 PIRSF PIRSF001467 6 145 1.3E-40 T 29-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 4.3E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 4.3E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 4.3E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 4.3E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 4.3E-27 T 29-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CSW12_RS07370 4aa0f188d3a5d328c44eed29d0605342 145 SUPERFAMILY SSF50891 14 138 5.7E-47 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 Pfam PF08279 HTH domain 9 61 5.7E-12 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 PIRSF PIRSF026546 4 210 1.1E-101 T 29-03-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 SUPERFAMILY SSF46785 5 79 3.37E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 SMART SM00116 86 134 0.0038 T 29-03-2018 IPR000644 CBS domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 SMART SM00116 153 204 0.41 T 29-03-2018 IPR000644 CBS domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 Gene3D G3DSA:1.10.10.10 4 64 6.4E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 Gene3D G3DSA:3.10.580.10 65 210 5.0E-26 T 29-03-2018 CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 Pfam PF00571 CBS domain 147 204 2.4E-5 T 29-03-2018 IPR000644 CBS domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 Pfam PF00571 CBS domain 82 134 1.2E-5 T 29-03-2018 IPR000644 CBS domain CSW12_RS21095 fc5b06577451dbbe2ba03569d5ae9dbd 210 SUPERFAMILY SSF54631 74 205 8.46E-23 T 29-03-2018 CSW12_RS05010 fd576e2e54b2c7141f67eb4b7e69f0b0 59 SUPERFAMILY SSF140500 3 49 4.19E-15 T 29-03-2018 CSW12_RS05010 fd576e2e54b2c7141f67eb4b7e69f0b0 59 Pfam PF09388 Spo0E like sporulation regulatory protein 3 39 7.2E-15 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CSW12_RS18675 2b593e5f6b916cd1644b921468eecb5f 445 SUPERFAMILY SSF161070 5 442 9.68E-131 T 29-03-2018 CSW12_RS18675 2b593e5f6b916cd1644b921468eecb5f 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 40 59 8.4E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS18675 2b593e5f6b916cd1644b921468eecb5f 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 86 112 8.4E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS18675 2b593e5f6b916cd1644b921468eecb5f 445 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 11 32 8.4E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS18675 2b593e5f6b916cd1644b921468eecb5f 445 Pfam PF00209 Sodium:neurotransmitter symporter family 148 440 9.7E-28 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS18675 2b593e5f6b916cd1644b921468eecb5f 445 Pfam PF00209 Sodium:neurotransmitter symporter family 4 122 3.2E-23 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS11580 7311a79214d13fd9fb9cfc230b599611 63 Pfam PF04070 Domain of unknown function (DUF378) 2 56 2.7E-16 T 29-03-2018 IPR007211 Protein of unknown function DUF378 CSW12_RS17715 93c8993cb8658e8453095558037d2714 553 Gene3D G3DSA:3.90.76.10 67 176 2.0E-29 T 29-03-2018 CSW12_RS17715 93c8993cb8658e8453095558037d2714 553 Gene3D G3DSA:3.10.105.10 313 522 3.3E-46 T 29-03-2018 CSW12_RS17715 93c8993cb8658e8453095558037d2714 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 470 3.3E-77 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS17715 93c8993cb8658e8453095558037d2714 553 SUPERFAMILY SSF53850 38 549 5.43E-118 T 29-03-2018 CSW12_RS17715 93c8993cb8658e8453095558037d2714 553 Gene3D G3DSA:3.40.190.10 177 312 1.2E-36 T 29-03-2018 CSW12_RS17715 93c8993cb8658e8453095558037d2714 553 PIRSF PIRSF002741 1 553 8.7E-101 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 Pfam PF00206 Lyase 7 301 2.0E-83 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 1.2E-29 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 1.2E-29 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 1.2E-29 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 1.2E-29 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 SUPERFAMILY SSF48557 7 457 3.93E-155 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 2.3E-70 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 2.3E-70 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 2.3E-70 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 2.3E-70 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 2.3E-70 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 2.3E-70 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 453 8.0E-214 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 5.7E-24 T 29-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 Gene3D G3DSA:1.20.200.10 108 375 1.0E-96 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 Gene3D G3DSA:1.10.40.30 376 433 6.5E-24 T 29-03-2018 CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 Gene3D G3DSA:1.10.275.10 3 107 4.0E-40 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS22765 96a5786cd20eaf787e5370535b965bc4 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.222 T 29-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS21175 9757fec591ae63ab6058e8ea17802663 249 PIRSF PIRSF015601 1 248 6.1E-64 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS21175 9757fec591ae63ab6058e8ea17802663 249 Gene3D G3DSA:3.40.1280.10 1 248 1.1E-77 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CSW12_RS21175 9757fec591ae63ab6058e8ea17802663 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 5 248 3.0E-70 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS21175 9757fec591ae63ab6058e8ea17802663 249 Pfam PF04452 RNA methyltransferase 17 243 2.3E-73 T 29-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS21175 9757fec591ae63ab6058e8ea17802663 249 SUPERFAMILY SSF88697 1 67 1.32E-11 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS21175 9757fec591ae63ab6058e8ea17802663 249 SUPERFAMILY SSF75217 72 248 2.09E-56 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 SUPERFAMILY SSF88946 28 81 5.3E-6 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 9.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 9.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 9.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 186 1.9E-17 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 Gene3D G3DSA:1.10.1740.10 1 82 8.0E-11 T 29-03-2018 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 Pfam PF08281 Sigma-70, region 4 138 186 1.9E-8 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 Gene3D G3DSA:1.10.10.10 107 194 1.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 Pfam PF04542 Sigma-70 region 2 29 80 8.7E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 SUPERFAMILY SSF88659 120 187 5.75E-8 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02390 bc14123de2b9b3fc0290b5d8652c9554 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS27505 ce00eae14573951d24ef410d22af984e 278 Pfam PF04468 PSP1 C-terminal conserved region 64 149 9.5E-33 T 29-03-2018 IPR007557 PSP1, C-terminal CSW12_RS12140 075f7b0d16c0e5396386474c39a182c1 214 Gene3D G3DSA:3.40.50.850 1 207 4.5E-35 T 29-03-2018 CSW12_RS12140 075f7b0d16c0e5396386474c39a182c1 214 Pfam PF00857 Isochorismatase family 12 163 1.8E-24 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS12140 075f7b0d16c0e5396386474c39a182c1 214 SUPERFAMILY SSF52499 3 204 3.92E-49 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 SMART SM00642 152 504 1.3E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF00128 Alpha amylase, catalytic domain 175 250 1.3E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF00128 Alpha amylase, catalytic domain 278 472 4.4E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 15 617 7.7E-259 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Gene3D G3DSA:2.60.40.1180 527 628 4.7E-33 T 29-03-2018 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 SUPERFAMILY SSF51445 81 508 2.54E-106 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 SUPERFAMILY SSF51011 515 619 6.48E-32 T 29-03-2018 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 520 618 4.8E-22 T 29-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Gene3D G3DSA:2.60.40.10 21 134 5.0E-31 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 26 108 4.6E-21 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Gene3D G3DSA:3.20.20.80 138 526 5.4E-75 T 29-03-2018 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 1 619 40.71 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CSW12_RS24095 844ce44641570d22f0ab0db1d1c04fac 645 PIRSF PIRSF000463 3 629 3.1E-260 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CSW12_RS02770 4bcd482b048b66163df63da74966a520 240 Pfam PF02421 Ferrous iron transport protein B 5 157 1.2E-60 T 29-03-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CSW12_RS02770 4bcd482b048b66163df63da74966a520 240 SUPERFAMILY SSF52540 5 210 5.82E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02770 4bcd482b048b66163df63da74966a520 240 Gene3D G3DSA:3.40.50.300 2 193 3.9E-31 T 29-03-2018 CSW12_RS02770 4bcd482b048b66163df63da74966a520 240 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 7.9E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS02770 4bcd482b048b66163df63da74966a520 240 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 54 69 7.9E-6 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS14840 e4d01defe201382e3694bb9ca2a9c161 563 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 14 561 1.5E-237 T 29-03-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related CSW12_RS14840 e4d01defe201382e3694bb9ca2a9c161 563 Pfam PF01432 Peptidase family M3 163 549 8.7E-45 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CSW12_RS14840 e4d01defe201382e3694bb9ca2a9c161 563 SUPERFAMILY SSF55486 32 558 2.51E-92 T 29-03-2018 CSW12_RS14840 e4d01defe201382e3694bb9ca2a9c161 563 Gene3D G3DSA:1.10.1370.10 35 320 1.2E-23 T 29-03-2018 CSW12_RS14840 e4d01defe201382e3694bb9ca2a9c161 563 Gene3D G3DSA:1.10.1370.10 343 551 2.4E-22 T 29-03-2018 CSW12_RS24750 9d72b3d75401145b95a455f86ef02bec 102 SUPERFAMILY SSF52833 4 100 1.77E-16 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS24750 9d72b3d75401145b95a455f86ef02bec 102 Pfam PF00085 Thioredoxin 14 90 1.7E-9 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CSW12_RS24750 9d72b3d75401145b95a455f86ef02bec 102 Gene3D G3DSA:3.40.30.10 3 102 3.9E-14 T 29-03-2018 CSW12_RS02625 9466908da09ff067631a7721698c23c7 75 SUPERFAMILY SSF47413 4 70 1.02E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02625 9466908da09ff067631a7721698c23c7 75 SMART SM00530 9 64 7.2E-13 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02625 9466908da09ff067631a7721698c23c7 75 Pfam PF01381 Helix-turn-helix 10 63 1.3E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02625 9466908da09ff067631a7721698c23c7 75 Gene3D G3DSA:1.10.260.40 2 74 3.7E-16 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 36 47 1.4E-36 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 173 186 1.4E-36 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 6 23 1.4E-36 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 137 147 1.4E-36 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 81 96 1.4E-36 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 PRINTS PR00988 Uridine kinase signature 151 162 1.4E-36 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 Gene3D G3DSA:3.40.50.300 2 212 6.8E-63 T 29-03-2018 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 SUPERFAMILY SSF52540 4 198 3.93E-50 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 8 193 2.3E-40 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 TIGRFAM TIGR00235 udk: uridine kinase 2 207 9.7E-91 T 29-03-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 CSW12_RS21535 bca9c1ccea591a946729d86e30851eff 212 Hamap MF_00551 Uridine kinase [udk]. 3 207 40.893 T 29-03-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 CSW12_RS28100 655b431335a7bd76b1d6c7d3440f8898 72 SUPERFAMILY SSF50249 1 71 7.89E-29 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS28100 655b431335a7bd76b1d6c7d3440f8898 72 SMART SM00316 4 72 6.8E-6 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS28100 655b431335a7bd76b1d6c7d3440f8898 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.88 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CSW12_RS28100 655b431335a7bd76b1d6c7d3440f8898 72 Gene3D G3DSA:2.40.50.140 1 72 3.7E-37 T 29-03-2018 CSW12_RS28100 655b431335a7bd76b1d6c7d3440f8898 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 9.9E-29 T 29-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CSW12_RS28100 655b431335a7bd76b1d6c7d3440f8898 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 4.4E-39 T 29-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 Gene3D G3DSA:3.60.120.10 2 475 2.1E-162 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 PRINTS PR00095 Anthranilate synthase component I signature 408 422 8.6E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 PRINTS PR00095 Anthranilate synthase component I signature 314 327 8.6E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 PRINTS PR00095 Anthranilate synthase component I signature 328 341 8.6E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 PRINTS PR00095 Anthranilate synthase component I signature 423 437 8.6E-24 T 29-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 Pfam PF00425 chorismate binding enzyme 213 466 5.0E-99 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 SUPERFAMILY SSF56322 20 474 1.96E-157 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 162 9.2E-36 T 29-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS05715 8a9ec82453d45a8e5950d39b81ce8811 475 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 474 4.0E-178 T 29-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS28165 7b49d40d808fd501ef5e1b0ae4f87292 237 Gene3D G3DSA:3.40.630.40 30 230 2.1E-54 T 29-03-2018 CSW12_RS28165 7b49d40d808fd501ef5e1b0ae4f87292 237 SUPERFAMILY SSF53187 40 231 5.34E-52 T 29-03-2018 CSW12_RS28165 7b49d40d808fd501ef5e1b0ae4f87292 237 SMART SM00646 115 226 7.4E-32 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS28165 7b49d40d808fd501ef5e1b0ae4f87292 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 42 226 5.6E-47 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS28165 7b49d40d808fd501ef5e1b0ae4f87292 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 40 228 1.7E-83 T 29-03-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD CSW12_RS15735 2e77716c0caa969f3bea42f577ed94e3 297 Gene3D G3DSA:3.30.420.40 1 120 6.1E-16 T 29-03-2018 CSW12_RS15735 2e77716c0caa969f3bea42f577ed94e3 297 SUPERFAMILY SSF53067 1 107 1.51E-18 T 29-03-2018 CSW12_RS15735 2e77716c0caa969f3bea42f577ed94e3 297 SUPERFAMILY SSF53067 110 296 1.19E-42 T 29-03-2018 CSW12_RS15735 2e77716c0caa969f3bea42f577ed94e3 297 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 256 3.1E-21 T 29-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CSW12_RS15735 2e77716c0caa969f3bea42f577ed94e3 297 Gene3D G3DSA:3.30.420.40 121 267 3.2E-31 T 29-03-2018 CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 SUPERFAMILY SSF46785 151 226 3.71E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 SMART SM00100 13 133 2.4E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 SUPERFAMILY SSF51206 22 139 1.7E-25 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 Gene3D G3DSA:1.10.10.10 138 233 1.8E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 2.7E-9 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 Pfam PF00027 Cyclic nucleotide-binding domain 35 116 3.6E-16 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS16030 5023ea7eff52b2234524b2db74fc8cc4 233 Gene3D G3DSA:2.60.120.10 16 137 7.6E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 305 95.683 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 25 301 6.1E-78 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 Gene3D G3DSA:3.90.78.10 218 305 1.9E-27 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 300 1.1E-29 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 Gene3D G3DSA:3.30.43.10 14 87 8.3E-22 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 Pfam PF01565 FAD binding domain 38 166 3.5E-27 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 SUPERFAMILY SSF56194 200 302 1.19E-37 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 SUPERFAMILY SSF56176 3 194 2.29E-48 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS25165 32e37046d197ff9bda52c373c67c3ad9 305 Gene3D G3DSA:3.30.465.10 91 217 6.4E-39 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 Gene3D G3DSA:2.60.40.10 102 204 1.2E-23 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 SMART SM00642 238 613 8.2E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 94 690 2.4E-269 T 29-03-2018 IPR011840 Pullulanase, type I CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 SUPERFAMILY SSF51445 207 620 1.04E-120 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 105 181 2.8E-14 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 SUPERFAMILY SSF81296 98 200 7.2E-22 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 Gene3D G3DSA:2.60.40.1180 625 713 1.4E-18 T 29-03-2018 CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 Gene3D G3DSA:3.20.20.80 205 624 1.6E-82 T 29-03-2018 CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 Pfam PF00128 Alpha amylase, catalytic domain 376 575 1.7E-7 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS23195 4b8f7ef26af8fd89f816b6581890984d 713 Pfam PF00128 Alpha amylase, catalytic domain 258 342 4.1E-6 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS00670 ce83dbbfc44dc33d84ca1affea5df5fc 361 Pfam PF00487 Fatty acid desaturase 54 299 1.4E-37 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CSW12_RS29280 65b950d643f4d22d2f8f74d7c997b482 75 SUPERFAMILY SSF47413 6 68 7.32E-10 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS29280 65b950d643f4d22d2f8f74d7c997b482 75 Gene3D G3DSA:1.10.260.40 7 73 7.0E-10 T 29-03-2018 CSW12_RS29280 65b950d643f4d22d2f8f74d7c997b482 75 SMART SM00530 9 64 1.3E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29280 65b950d643f4d22d2f8f74d7c997b482 75 Pfam PF12844 Helix-turn-helix domain 10 65 9.0E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS04075 0fd255581643bd75ec7bb81b22d53e2b 194 Gene3D G3DSA:1.10.3300.10 1 191 5.4E-34 T 29-03-2018 IPR023286 ABATE domain CSW12_RS04075 0fd255581643bd75ec7bb81b22d53e2b 194 SUPERFAMILY SSF160904 5 189 2.22E-33 T 29-03-2018 CSW12_RS04075 0fd255581643bd75ec7bb81b22d53e2b 194 Pfam PF07336 Putative stress-induced transcription regulator 12 143 8.5E-12 T 29-03-2018 IPR010852 Putative stress-induced transcription regulator CSW12_RS04075 0fd255581643bd75ec7bb81b22d53e2b 194 Pfam PF11706 CGNR zinc finger 150 190 1.2E-15 T 29-03-2018 IPR021005 Zinc finger, CGNR CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 459 2.9E-235 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 460 92.258 T 29-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 Pfam PF10415 Fumarase C C-terminus 406 458 7.3E-28 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 Gene3D G3DSA:1.10.40.30 413 460 4.6E-29 T 29-03-2018 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 Gene3D G3DSA:1.10.275.10 1 135 1.5E-63 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 4.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 4.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 4.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 4.8E-34 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 SUPERFAMILY SSF48557 3 458 3.77E-154 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 Gene3D G3DSA:1.20.200.10 136 412 1.4E-84 T 29-03-2018 CSW12_RS18965 d731f565f971eeb07bf615e3178e9527 462 Pfam PF00206 Lyase 11 340 1.3E-115 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CSW12_RS08625 d52626647a5289ae3046bd1c640f6611 180 Gene3D G3DSA:3.60.20.10 7 180 6.3E-27 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS08625 d52626647a5289ae3046bd1c640f6611 180 PIRSF PIRSF039093 1 180 2.7E-85 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CSW12_RS08625 d52626647a5289ae3046bd1c640f6611 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.219 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CSW12_RS08625 d52626647a5289ae3046bd1c640f6611 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 5.4E-85 T 29-03-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CSW12_RS08625 d52626647a5289ae3046bd1c640f6611 180 SUPERFAMILY SSF56235 4 179 9.77E-60 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS08625 d52626647a5289ae3046bd1c640f6611 180 Pfam PF00227 Proteasome subunit 5 178 3.8E-25 T 29-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 Gene3D G3DSA:3.50.30.10 767 867 4.6E-31 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 315 2.7E-94 T 29-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 SUPERFAMILY SSF56059 1 341 2.0E-95 T 29-03-2018 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 SUPERFAMILY SSF52009 762 866 1.57E-27 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 Pfam PF00391 PEP-utilising enzyme, mobile domain 792 863 9.8E-22 T 29-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 Gene3D G3DSA:3.30.1490.20 1 183 5.0E-54 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS12210 770f912d387125ad293840e224ab9c96 868 Gene3D G3DSA:3.30.470.20 184 314 1.1E-44 T 29-03-2018 CSW12_RS27715 68d15c0552b52ef619cda553b3349027 280 SUPERFAMILY SSF51717 12 276 2.22E-103 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS27715 68d15c0552b52ef619cda553b3349027 280 Gene3D G3DSA:3.20.20.20 4 280 3.9E-113 T 29-03-2018 CSW12_RS27715 68d15c0552b52ef619cda553b3349027 280 Pfam PF00809 Pterin binding enzyme 26 259 3.2E-88 T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS27715 68d15c0552b52ef619cda553b3349027 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 59 72 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS27715 68d15c0552b52ef619cda553b3349027 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 25 40 - T 29-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS27715 68d15c0552b52ef619cda553b3349027 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 25 274 2.7E-101 T 29-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CSW12_RS24855 97974a3112806163b93067b865b5697c 100 SUPERFAMILY SSF89957 1 100 1.3E-32 T 29-03-2018 IPR029756 MTH1187/YkoF-like CSW12_RS24855 97974a3112806163b93067b865b5697c 100 Gene3D G3DSA:3.30.70.930 1 97 1.2E-36 T 29-03-2018 IPR029756 MTH1187/YkoF-like CSW12_RS24855 97974a3112806163b93067b865b5697c 100 Pfam PF01910 Thiamine-binding protein 4 97 6.2E-35 T 29-03-2018 IPR002767 Thiamine-binding protein CSW12_RS24855 97974a3112806163b93067b865b5697c 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 100 1.2E-33 T 29-03-2018 IPR002767 Thiamine-binding protein CSW12_RS12350 6cca96ab0f137d57a968ffa88efae358 174 SUPERFAMILY SSF55811 5 145 5.28E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS12350 6cca96ab0f137d57a968ffa88efae358 174 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS12350 6cca96ab0f137d57a968ffa88efae358 174 Gene3D G3DSA:3.90.79.10 3 161 6.7E-22 T 29-03-2018 CSW12_RS12350 6cca96ab0f137d57a968ffa88efae358 174 Pfam PF00293 NUDIX domain 6 99 1.2E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 SUPERFAMILY SSF56420 1 148 3.93E-54 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 Gene3D G3DSA:3.90.45.10 4 155 2.4E-54 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 119 148 3.4E-35 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 100 118 3.4E-35 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 88 99 3.4E-35 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 PRINTS PR01576 Peptide deformylase signature 33 62 3.4E-35 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 153 7.7E-53 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 Hamap MF_00163 Peptide deformylase [def]. 2 155 27.809 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 PIRSF PIRSF004749 1 155 1.5E-47 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS08435 6b5dac54a02dac618033c9b41404c850 156 Pfam PF01327 Polypeptide deformylase 4 148 8.3E-47 T 29-03-2018 IPR023635 Peptide deformylase CSW12_RS09540 99309bfb37a822bb9771a752be6f4cb0 202 Pfam PF02230 Phospholipase/Carboxylesterase 6 197 1.2E-9 T 29-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CSW12_RS09540 99309bfb37a822bb9771a752be6f4cb0 202 Gene3D G3DSA:3.40.50.1820 2 202 2.1E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS09540 99309bfb37a822bb9771a752be6f4cb0 202 SUPERFAMILY SSF53474 2 200 6.22E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS10100 2c33d87be92785f15271d63067b148f5 305 SUPERFAMILY SSF55729 43 244 1.01E-5 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS10100 2c33d87be92785f15271d63067b148f5 305 Gene3D G3DSA:3.40.630.30 4 143 0.041 T 29-03-2018 CSW12_RS10100 2c33d87be92785f15271d63067b148f5 305 Gene3D G3DSA:3.40.630.30 168 305 0.0033 T 29-03-2018 CSW12_RS20725 81cd5cb8ebb0a3f7da1a31088d442ebb 491 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 60.628 T 29-03-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CSW12_RS20725 81cd5cb8ebb0a3f7da1a31088d442ebb 491 Gene3D G3DSA:3.40.640.10 83 344 3.5E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20725 81cd5cb8ebb0a3f7da1a31088d442ebb 491 Gene3D G3DSA:3.90.1150.10 345 470 9.4E-45 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20725 81cd5cb8ebb0a3f7da1a31088d442ebb 491 Pfam PF02347 Glycine cleavage system P-protein 51 300 3.4E-9 T 29-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CSW12_RS20725 81cd5cb8ebb0a3f7da1a31088d442ebb 491 SUPERFAMILY SSF53383 12 483 9.18E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 4.0E-149 T 29-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 SUPERFAMILY SSF51726 5 391 4.97E-98 T 29-03-2018 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 SUPERFAMILY SSF51726 395 754 1.31E-109 T 29-03-2018 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 313 1.3E-120 T 29-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 757 34.408 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 PIRSF PIRSF000382 2 762 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 756 0.0 T 29-03-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 Gene3D G3DSA:3.20.20.210 3 388 2.6E-127 T 29-03-2018 CSW12_RS07720 617fe343ae70e60c03b743334347548e 762 Gene3D G3DSA:3.20.20.210 389 757 9.1E-115 T 29-03-2018 CSW12_RS00350 2e26dc0a58bdb3c40ba370bb51a65eee 227 Pfam PF05709 Phage tail protein 27 226 1.8E-8 T 29-03-2018 IPR008841 Siphovirus-type tail component CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 PIRSF PIRSF000477 1 271 6.5E-123 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 SUPERFAMILY SSF53167 4 271 2.49E-102 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 Pfam PF01048 Phosphorylase superfamily 23 268 3.1E-60 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 269 7.9E-113 T 29-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 Gene3D G3DSA:3.40.50.1580 1 271 1.0E-76 T 29-03-2018 CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 268 7.8E-121 T 29-03-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CSW12_RS07240 50a3d270caf0873da4e4a76572223c45 273 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 29-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 SUPERFAMILY SSF52210 123 287 9.03E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 SMART SM00881 4 100 8.7E-37 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.8E-40 T 29-03-2018 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.8E-40 T 29-03-2018 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.8E-40 T 29-03-2018 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.8E-40 T 29-03-2018 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 43.943 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 PIRSF PIRSF001553 1 291 9.8E-134 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 29-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 1.9E-147 T 29-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 29-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 Gene3D G3DSA:3.40.50.261 120 298 9.7E-57 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 Gene3D G3DSA:3.40.50.720 1 119 3.2E-46 T 29-03-2018 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 Pfam PF00549 CoA-ligase 151 268 5.2E-18 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 SUPERFAMILY SSF51735 1 122 3.94E-44 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS08600 36a9d133f07d823f73627e0431f160cf 300 Pfam PF02629 CoA binding domain 6 99 1.4E-32 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CSW12_RS25010 53b56f90970fa4cb353696215ffe85ca 232 SUPERFAMILY SSF51182 5 229 3.2E-68 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS25010 53b56f90970fa4cb353696215ffe85ca 232 Pfam PF02678 Pirin 12 118 1.5E-33 T 29-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CSW12_RS25010 53b56f90970fa4cb353696215ffe85ca 232 PIRSF PIRSF006232 1 230 2.1E-58 T 29-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CSW12_RS25010 53b56f90970fa4cb353696215ffe85ca 232 Gene3D G3DSA:2.60.120.10 135 231 2.0E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS25010 53b56f90970fa4cb353696215ffe85ca 232 Gene3D G3DSA:2.60.120.10 12 134 3.4E-46 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS05700 61a1a4d5d24319d3b6120983cd10568c 132 SUPERFAMILY SSF49373 39 121 4.32E-9 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CSW12_RS05700 61a1a4d5d24319d3b6120983cd10568c 132 Gene3D G3DSA:2.60.40.1080 37 127 8.5E-13 T 29-03-2018 CSW12_RS21320 0f6aa64d5d977425248d9521a314d6f7 262 Pfam PF02666 Phosphatidylserine decarboxylase 59 256 4.6E-58 T 29-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CSW12_RS21320 0f6aa64d5d977425248d9521a314d6f7 262 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 257 3.3E-52 T 29-03-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CSW12_RS21320 0f6aa64d5d977425248d9521a314d6f7 262 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 259 40.494 T 29-03-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CSW12_RS13310 f38773fc0762899bb3c7328bc9087792 143 Pfam PF00583 Acetyltransferase (GNAT) family 32 109 3.9E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13310 f38773fc0762899bb3c7328bc9087792 143 Gene3D G3DSA:3.40.630.30 2 139 5.6E-15 T 29-03-2018 CSW12_RS13310 f38773fc0762899bb3c7328bc9087792 143 SUPERFAMILY SSF55729 1 117 1.15E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 SUPERFAMILY SSF51905 1 353 9.98E-38 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 Gene3D G3DSA:3.50.50.60 297 383 4.9E-8 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 Gene3D G3DSA:3.40.50.720 144 296 2.1E-5 T 29-03-2018 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 342 1.0E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 Gene3D G3DSA:3.50.50.60 1 143 1.2E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 9.4E-16 T 29-03-2018 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 308 330 9.4E-16 T 29-03-2018 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 9.4E-16 T 29-03-2018 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.4E-16 T 29-03-2018 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 318 336 1.4E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS13485 dc23fa895265e3af16caff7348635666 414 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.4E-9 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS30085 9bee05d061a3104843c542df9a391ce9 114 Gene3D G3DSA:3.90.120.10 2 101 3.4E-18 T 29-03-2018 CSW12_RS30085 9bee05d061a3104843c542df9a391ce9 114 SUPERFAMILY SSF53335 39 114 2.77E-15 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS30085 9bee05d061a3104843c542df9a391ce9 114 Pfam PF00145 C-5 cytosine-specific DNA methylase 39 113 7.0E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS30085 9bee05d061a3104843c542df9a391ce9 114 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 95 113 - T 29-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CSW12_RS14020 e4ba659f538f280802871d7909fb09e6 171 Pfam PF12867 DinB superfamily 9 160 5.1E-19 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS14020 e4ba659f538f280802871d7909fb09e6 171 Gene3D G3DSA:1.20.120.450 5 168 6.8E-25 T 29-03-2018 CSW12_RS14020 e4ba659f538f280802871d7909fb09e6 171 SUPERFAMILY SSF109854 8 165 1.22E-27 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS23865 63d43fae8d0adac5d8d5a3aa1aa91e34 649 Gene3D G3DSA:1.10.287.70 5 551 0.066 T 29-03-2018 CSW12_RS23865 63d43fae8d0adac5d8d5a3aa1aa91e34 649 Pfam PF02687 FtsX-like permease family 85 170 9.3E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS23865 63d43fae8d0adac5d8d5a3aa1aa91e34 649 PIRSF PIRSF018968 1 649 1.5E-126 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 Gene3D G3DSA:1.10.287.100 113 147 7.0E-15 T 29-03-2018 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 Pfam PF01047 MarR family 35 93 2.0E-18 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 SMART SM00347 28 128 6.3E-28 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 Gene3D G3DSA:1.10.10.10 5 112 4.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.8E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.8E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.8E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS02015 d8b898616e90fcfb0ce91b79f3158dbf 152 SUPERFAMILY SSF46785 3 143 1.09E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00420 7b0f9643e64c3c763a143ce1c4f5f789 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 5.1E-33 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CSW12_RS00420 7b0f9643e64c3c763a143ce1c4f5f789 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 25.744 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CSW12_RS00420 7b0f9643e64c3c763a143ce1c4f5f789 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.4E-22 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CSW12_RS00420 7b0f9643e64c3c763a143ce1c4f5f789 96 SUPERFAMILY SSF141000 4 94 5.62E-32 T 29-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CSW12_RS01095 e7eebd9d1b208db0bd8d5b278be4b278 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 5.0E-125 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CSW12_RS01095 e7eebd9d1b208db0bd8d5b278be4b278 309 SUPERFAMILY SSF56601 6 309 5.45E-114 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS01095 e7eebd9d1b208db0bd8d5b278be4b278 309 Gene3D G3DSA:3.40.710.10 4 309 1.0E-116 T 29-03-2018 CSW12_RS01095 e7eebd9d1b208db0bd8d5b278be4b278 309 Pfam PF04960 Glutaminase 23 309 4.9E-112 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CSW12_RS01095 e7eebd9d1b208db0bd8d5b278be4b278 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 47.277 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CSW12_RS26905 ffc3c0f8f47829b2b9542cc0e9433b8a 437 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 129 272 4.3E-11 T 29-03-2018 CSW12_RS14185 9bee15ad5451af3dae412e4ff51d8bc6 439 SUPERFAMILY SSF51905 4 195 1.96E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS14185 9bee15ad5451af3dae412e4ff51d8bc6 439 SUPERFAMILY SSF51905 302 351 1.96E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS14185 9bee15ad5451af3dae412e4ff51d8bc6 439 Gene3D G3DSA:3.50.50.60 4 400 1.1E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS14185 9bee15ad5451af3dae412e4ff51d8bc6 439 Pfam PF01494 FAD binding domain 151 339 3.2E-5 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CSW12_RS11395 3ada27b4c4861934a9abd94a243cf143 292 Pfam PF02361 Cobalt transport protein 18 211 1.3E-9 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CSW12_RS11395 3ada27b4c4861934a9abd94a243cf143 292 Gene3D G3DSA:1.10.287.70 11 280 0.0059 T 29-03-2018 CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 Gene3D G3DSA:1.10.10.10 124 182 1.1E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 SUPERFAMILY SSF88659 106 178 4.86E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 SUPERFAMILY SSF88946 4 112 3.92E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 177 5.7E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 Pfam PF08281 Sigma-70, region 4 121 174 6.6E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 Gene3D G3DSA:1.10.1740.10 1 123 4.1E-15 T 29-03-2018 CSW12_RS19045 0ef0f9cb031a489b104d0297dc5729c8 188 Pfam PF04542 Sigma-70 region 2 24 94 1.8E-10 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 897 925 5.2E-13 T 29-03-2018 IPR017502 Sortase B cell surface sorting signal CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 Pfam PF05031 Iron Transport-associated domain 184 300 3.3E-33 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 Pfam PF05031 Iron Transport-associated domain 722 838 1.7E-36 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 Pfam PF05031 Iron Transport-associated domain 22 137 2.2E-37 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 Pfam PF05031 Iron Transport-associated domain 553 668 4.3E-37 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 Pfam PF05031 Iron Transport-associated domain 393 509 1.5E-38 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 Gene3D G3DSA:2.60.40.60 609 687 0.17 T 29-03-2018 CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SMART SM00725 23 144 2.4E-46 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SMART SM00725 395 516 4.6E-47 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SMART SM00725 554 675 3.0E-43 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SMART SM00725 723 844 6.7E-42 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SMART SM00725 186 307 1.9E-31 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SUPERFAMILY SSF158911 546 681 7.85E-48 T 29-03-2018 CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SUPERFAMILY SSF158911 716 846 1.44E-47 T 29-03-2018 CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SUPERFAMILY SSF158911 391 522 8.11E-49 T 29-03-2018 CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SUPERFAMILY SSF158911 5 150 1.09E-49 T 29-03-2018 CSW12_RS22340 90533c14cef7fdeac9d8942edad050de 929 SUPERFAMILY SSF158911 175 313 1.96E-43 T 29-03-2018 CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 Gene3D G3DSA:2.40.50.140 1 81 2.5E-24 T 29-03-2018 CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 28.869 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 SUPERFAMILY SSF57863 80 231 2.07E-45 T 29-03-2018 CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 5.9E-76 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 Pfam PF11967 Recombination protein O N terminal 1 77 5.4E-26 T 29-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 Pfam PF02565 Recombination protein O C terminal 82 238 3.9E-34 T 29-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CSW12_RS21100 dce0045a35f9b56a8a3796e2f8b65d4e 248 SUPERFAMILY SSF50249 1 77 1.11E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 3.0E-8 T 29-03-2018 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-8 T 29-03-2018 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 Gene3D G3DSA:3.50.50.60 2 151 4.4E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 SUPERFAMILY SSF51905 162 317 2.36E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 Gene3D G3DSA:3.50.50.60 175 344 4.6E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 Gene3D G3DSA:3.50.50.60 152 174 0.038 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 SUPERFAMILY SSF51905 2 191 1.59E-37 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 191 6.1E-42 T 29-03-2018 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.7E-13 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.7E-13 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS10685 f603343e70898c96aec8f5c140d7819c 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 1.7E-13 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.30.190.20 140 249 1.1E-45 T 29-03-2018 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 8 924 0.0 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 SUPERFAMILY SSF52540 619 909 2.6E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:1.10.8.280 286 395 8.5E-40 T 29-03-2018 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.40.50.300 396 600 7.1E-26 T 29-03-2018 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.40.50.300 5 38 0.016 T 29-03-2018 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 SUPERFAMILY SSF52540 15 208 8.78E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 SUPERFAMILY SSF52540 432 571 8.78E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Hamap MF_00205 UvrABC system protein A [uvrA]. 5 940 23.5 T 29-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.40.50.300 610 953 6.8E-58 T 29-03-2018 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Pfam PF00005 ABC transporter 624 860 1.5E-9 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25520 e1d6d281091f35459bdb886428c84725 958 Gene3D G3DSA:3.40.50.300 39 139 1.2E-4 T 29-03-2018 CSW12_RS04625 9d1dc70d427a33a84f9168baef34ed4d 322 Gene3D G3DSA:1.25.40.10 24 178 3.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS11540 f91e2a901cdf8a233c6e17239de811be 1137 SUPERFAMILY SSF48371 779 815 1.84E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS11540 f91e2a901cdf8a233c6e17239de811be 1137 SUPERFAMILY SSF48371 683 742 1.84E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS11540 f91e2a901cdf8a233c6e17239de811be 1137 SUPERFAMILY SSF48371 508 639 1.84E-5 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS11540 f91e2a901cdf8a233c6e17239de811be 1137 Gene3D G3DSA:1.25.10.10 320 796 6.6E-4 T 29-03-2018 IPR011989 Armadillo-like helical CSW12_RS11540 f91e2a901cdf8a233c6e17239de811be 1137 Pfam PF13569 Domain of unknown function (DUF4132) 849 1031 1.8E-43 T 29-03-2018 IPR025406 Domain of unknown function DUF4132 CSW12_RS20485 fd6a653fc775355a278483835b129709 452 Pfam PF13742 OB-fold nucleic acid binding domain 6 101 6.1E-33 T 29-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CSW12_RS20485 fd6a653fc775355a278483835b129709 452 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 3 441 30.289 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20485 fd6a653fc775355a278483835b129709 452 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 7 353 5.3E-141 T 29-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20485 fd6a653fc775355a278483835b129709 452 Gene3D G3DSA:2.40.50.140 11 102 1.8E-10 T 29-03-2018 CSW12_RS20485 fd6a653fc775355a278483835b129709 452 Pfam PF02601 Exonuclease VII, large subunit 124 438 3.9E-99 T 29-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 Pfam PF00582 Universal stress protein family 5 144 9.1E-37 T 29-03-2018 IPR006016 UspA GO:0006950 CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 Gene3D G3DSA:3.40.50.620 1 151 4.3E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 SUPERFAMILY SSF52402 5 144 2.09E-35 T 29-03-2018 CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 PIRSF PIRSF006276 1 147 2.1E-22 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 PRINTS PR01438 Universal stress protein signature 104 116 7.9E-19 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 PRINTS PR01438 Universal stress protein signature 122 144 7.9E-19 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS22750 fba2c85b85571791e52cf057e8bc2d2f 152 PRINTS PR01438 Universal stress protein signature 5 23 7.9E-19 T 29-03-2018 IPR006015 Universal stress protein A CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00668 Condensation domain 862 1282 3.5E-52 T 29-03-2018 IPR001242 Condensation domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00668 Condensation domain 1915 2346 2.7E-89 T 29-03-2018 IPR001242 Condensation domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00668 Condensation domain 20 258 6.5E-11 T 29-03-2018 IPR001242 Condensation domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF56801 239 786 3.14E-141 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.40.50.980 1447 1605 6.3E-38 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.40.50.980 423 579 5.6E-32 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00501 AMP-binding enzyme 1315 1694 3.4E-93 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00501 AMP-binding enzyme 278 667 4.8E-101 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:1.10.1200.10 778 841 2.6E-16 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:1.10.1200.10 1806 1878 1.1E-18 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF52777 857 1054 2.22E-25 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 PRINTS PR00154 AMP-binding signature 1436 1447 9.8E-5 T 29-03-2018 IPR020459 AMP-binding CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 PRINTS PR00154 AMP-binding signature 1448 1456 9.8E-5 T 29-03-2018 IPR020459 AMP-binding CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF47336 766 838 9.68E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:2.30.38.10 1610 1687 2.5E-18 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1825 1840 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1441 1452 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.40.50.980 271 422 7.3E-47 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.40.50.980 1307 1446 2.0E-44 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:2.30.38.10 580 660 2.7E-20 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF52777 1040 1283 2.33E-44 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.30.559.10 842 1046 2.6E-18 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.30.559.10 1890 2110 8.4E-27 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF47336 1794 1865 1.57E-16 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF13193 AMP-binding enzyme C-terminal domain 675 747 4.1E-7 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF13193 AMP-binding enzyme C-terminal domain 1704 1776 2.4E-12 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 ProSitePatterns PS00455 Putative AMP-binding domain signature. 417 428 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 299 691 2.5E-129 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1336 1719 8.5E-116 T 29-03-2018 IPR010071 Amino acid adenylation domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF52777 25 242 1.56E-16 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF56801 1293 1814 7.06E-151 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.30.300.30 1690 1805 1.2E-39 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Gene3D G3DSA:3.30.300.30 662 777 3.7E-31 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF52777 2097 2339 1.56E-39 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 SUPERFAMILY SSF52777 1920 2108 5.78E-36 T 29-03-2018 CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00550 Phosphopantetheine attachment site 775 837 1.3E-8 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS14045 e1f4d11d069042edb318c5f0de9ed87c 2347 Pfam PF00550 Phosphopantetheine attachment site 1804 1865 3.0E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS13490 4bf226e0c8770c10ead0b5df234d278d 110 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 95 3.9E-27 T 29-03-2018 CSW12_RS13490 4bf226e0c8770c10ead0b5df234d278d 110 Gene3D G3DSA:3.10.20.30 16 92 4.8E-10 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS13490 4bf226e0c8770c10ead0b5df234d278d 110 SUPERFAMILY SSF54292 19 109 1.35E-22 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CSW12_RS18420 891de5f90f633d308a901dc8df4f9f9f 591 SMART SM01276 74 370 2.6E-97 T 29-03-2018 IPR031161 Peptidase family M60 domain CSW12_RS18420 891de5f90f633d308a901dc8df4f9f9f 591 Pfam PF00754 F5/8 type C domain 465 586 3.4E-23 T 29-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CSW12_RS18420 891de5f90f633d308a901dc8df4f9f9f 591 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 151 420 3.8E-52 T 29-03-2018 IPR031161 Peptidase family M60 domain CSW12_RS18420 891de5f90f633d308a901dc8df4f9f9f 591 Gene3D G3DSA:2.60.120.260 441 591 2.8E-29 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS18420 891de5f90f633d308a901dc8df4f9f9f 591 SUPERFAMILY SSF49785 453 590 6.45E-35 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS18420 891de5f90f633d308a901dc8df4f9f9f 591 Pfam PF17291 N-terminal domain of M60-like peptidases 66 149 2.7E-13 T 29-03-2018 IPR035423 M60-like domain, N-terminal CSW12_RS09725 adca56b29d97e8128613f7a61514cb69 198 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 192 20.22 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS09725 adca56b29d97e8128613f7a61514cb69 198 SMART SM01207 9 184 3.7E-82 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS09725 adca56b29d97e8128613f7a61514cb69 198 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 183 4.7E-52 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS09725 adca56b29d97e8128613f7a61514cb69 198 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 191 4.6E-63 T 29-03-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CSW12_RS11620 52a70f0b60cb39ead14df0e34c35b815 279 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 4.9E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS11620 52a70f0b60cb39ead14df0e34c35b815 279 PIRSF PIRSF006483 1 278 8.2E-82 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS11620 52a70f0b60cb39ead14df0e34c35b815 279 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 2.9E-60 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS06445 803ae23a6e71b9c8380972459719b21b 300 Pfam PF01636 Phosphotransferase enzyme family 23 247 1.7E-28 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS06445 803ae23a6e71b9c8380972459719b21b 300 SUPERFAMILY SSF56112 7 260 3.95E-33 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS06445 803ae23a6e71b9c8380972459719b21b 300 Gene3D G3DSA:3.90.1200.10 50 287 4.8E-22 T 29-03-2018 CSW12_RS09115 8339fd2536bf0ad3af2444af2c158097 273 Pfam PF00005 ABC transporter 20 167 1.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09115 8339fd2536bf0ad3af2444af2c158097 273 SUPERFAMILY SSF52540 3 231 2.92E-60 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09115 8339fd2536bf0ad3af2444af2c158097 273 SMART SM00382 28 217 1.9E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS09115 8339fd2536bf0ad3af2444af2c158097 273 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS09115 8339fd2536bf0ad3af2444af2c158097 273 Gene3D G3DSA:3.40.50.300 1 242 9.6E-60 T 29-03-2018 CSW12_RS25610 5a76c8a6754147fcc54072d137c5bf66 297 PIRSF PIRSF003097 1 297 6.9E-89 T 29-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CSW12_RS25610 5a76c8a6754147fcc54072d137c5bf66 297 Pfam PF02687 FtsX-like permease family 202 286 1.0E-5 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS22725 90734820b5661e3495ba37104623bc0d 262 Pfam PF12746 GNAT acetyltransferase 19 255 2.2E-61 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like CSW12_RS22725 90734820b5661e3495ba37104623bc0d 262 Gene3D G3DSA:3.40.630.30 113 247 3.8E-19 T 29-03-2018 CSW12_RS22725 90734820b5661e3495ba37104623bc0d 262 SUPERFAMILY SSF55729 128 246 4.36E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06080 623c094bf56e9d715b7af4ec204020aa 283 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 76 85 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CSW12_RS06080 623c094bf56e9d715b7af4ec204020aa 283 Pfam PF01226 Formate/nitrite transporter 9 251 1.2E-67 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CSW12_RS06080 623c094bf56e9d715b7af4ec204020aa 283 Gene3D G3DSA:1.20.1080.10 3 265 8.2E-75 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS06080 623c094bf56e9d715b7af4ec204020aa 283 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 160 170 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 Pfam PF12793 Sugar transport-related sRNA regulator N-term 5 95 6.1E-21 T 29-03-2018 IPR025370 Transcriptional regulator SgrR, N-terminal HTH domain CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 Gene3D G3DSA:3.90.76.10 160 260 1.7E-29 T 29-03-2018 CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 PIRSF PIRSF002741 129 579 3.5E-42 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 Gene3D G3DSA:3.10.105.10 367 550 1.0E-11 T 29-03-2018 CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 SUPERFAMILY SSF53850 147 578 5.07E-70 T 29-03-2018 CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 Gene3D G3DSA:3.40.190.10 261 366 1.4E-4 T 29-03-2018 CSW12_RS13270 421d65123d7e7d18056a1d341fc6dc57 579 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 180 499 1.3E-34 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS05665 b78779b9ee629754ae21b4e9d1ee7af6 688 Gene3D G3DSA:3.40.50.300 49 308 4.0E-50 T 29-03-2018 CSW12_RS05665 b78779b9ee629754ae21b4e9d1ee7af6 688 Pfam PF13361 UvrD-like helicase C-terminal domain 314 659 7.6E-44 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CSW12_RS05665 b78779b9ee629754ae21b4e9d1ee7af6 688 SUPERFAMILY SSF52540 45 682 6.83E-130 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS05665 b78779b9ee629754ae21b4e9d1ee7af6 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 51 154 5.0E-24 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CSW12_RS05665 b78779b9ee629754ae21b4e9d1ee7af6 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 155 309 2.1E-35 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CSW12_RS05665 b78779b9ee629754ae21b4e9d1ee7af6 688 Gene3D G3DSA:3.40.50.300 309 688 4.1E-51 T 29-03-2018 CSW12_RS16585 d9ac45f54ee40721ed63faa978233cd7 409 Pfam PF07690 Major Facilitator Superfamily 16 352 2.7E-23 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS16585 d9ac45f54ee40721ed63faa978233cd7 409 Gene3D G3DSA:1.20.1250.20 204 398 1.2E-13 T 29-03-2018 CSW12_RS16585 d9ac45f54ee40721ed63faa978233cd7 409 SUPERFAMILY SSF103473 13 398 1.44E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS16585 d9ac45f54ee40721ed63faa978233cd7 409 Gene3D G3DSA:1.20.1250.20 1 203 4.3E-18 T 29-03-2018 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 7.5E-6 T 29-03-2018 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 7.5E-6 T 29-03-2018 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 1.2E-31 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 1.2E-31 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 1.2E-31 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 1.2E-31 T 29-03-2018 IPR000362 Fumarate lyase family CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 Gene3D G3DSA:1.10.275.10 5 140 1.8E-52 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 29-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 SUPERFAMILY SSF48557 7 464 5.5E-148 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 Gene3D G3DSA:1.10.40.30 418 467 1.7E-23 T 29-03-2018 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 Pfam PF10415 Fumarase C C-terminus 410 463 7.7E-23 T 29-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 Gene3D G3DSA:1.20.200.10 141 417 2.6E-79 T 29-03-2018 CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 Pfam PF00206 Lyase 15 344 7.7E-111 T 29-03-2018 IPR022761 Fumarate lyase, N-terminal CSW12_RS01760 38ab7b02101bf243afbfea26f7768c22 477 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 8 468 9.7E-238 T 29-03-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 CSW12_RS05130 7b75c280b0ad05177b596b4e9015749f 139 Pfam PF12616 Protein of unknown function (DUF3775) 57 138 6.2E-5 T 29-03-2018 IPR022254 Protein of unknown function DUF3775 CSW12_RS07100 5240104772a1b810a644fb8c85a45f76 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.272 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CSW12_RS07100 5240104772a1b810a644fb8c85a45f76 349 Gene3D G3DSA:3.20.20.70 3 342 1.4E-60 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS07100 5240104772a1b810a644fb8c85a45f76 349 PIRSF PIRSF003314 2 340 2.2E-122 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CSW12_RS07100 5240104772a1b810a644fb8c85a45f76 349 Pfam PF01070 FMN-dependent dehydrogenase 167 323 1.1E-17 T 29-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CSW12_RS07100 5240104772a1b810a644fb8c85a45f76 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 1.2E-119 T 29-03-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CSW12_RS07100 5240104772a1b810a644fb8c85a45f76 349 SUPERFAMILY SSF51395 22 348 4.19E-84 T 29-03-2018 CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.4E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 Gene3D G3DSA:3.40.50.300 2 328 2.4E-76 T 29-03-2018 CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 SUPERFAMILY SSF52540 33 317 3.31E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 SMART SM00382 34 241 8.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 Pfam PF00005 ABC transporter 26 183 2.0E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS03845 274c93fea85a66804bb830e6191c6434 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 1.8E-26 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 SUPERFAMILY SSF53850 99 292 8.33E-27 T 29-03-2018 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 Gene3D G3DSA:1.10.10.10 1 93 3.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 Gene3D G3DSA:3.40.190.10 97 178 9.4E-15 T 29-03-2018 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 1.2E-15 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.8E-6 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 SUPERFAMILY SSF46785 8 120 8.84E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 Pfam PF03466 LysR substrate binding domain 97 289 2.6E-31 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS07825 e92db2d13c815c0f46b560dd292e7f06 294 Gene3D G3DSA:3.40.190.10 179 262 2.3E-7 T 29-03-2018 CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 SUPERFAMILY SSF53686 6 349 8.25E-106 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 Gene3D G3DSA:3.40.50.1100 37 143 2.3E-30 T 29-03-2018 CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 TIGRFAM TIGR00260 thrC: threonine synthase 8 322 1.2E-100 T 29-03-2018 IPR004450 Threonine synthase-like CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 Gene3D G3DSA:3.40.50.1100 144 331 4.1E-52 T 29-03-2018 CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 PIRSF PIRSF038945 1 347 1.1E-155 T 29-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CSW12_RS18015 f3c556e3681661b6070ad84cccef74f8 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 1.1E-79 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 SMART SM00450 6 109 4.2E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 SMART SM00849 130 294 3.0E-23 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 SUPERFAMILY SSF52821 2 110 5.37E-18 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 Gene3D G3DSA:3.40.250.10 1 116 6.0E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 Pfam PF00753 Metallo-beta-lactamase superfamily 130 273 2.5E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 Gene3D G3DSA:3.60.15.10 117 373 5.9E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 Pfam PF00581 Rhodanese-like domain 14 105 2.6E-10 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03225 0b70e658fbc5f4c7dcc05caecd053ed5 378 SUPERFAMILY SSF56281 122 358 4.6E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08605 685b763cfd8dcd13217c989a2cd5b7dc 289 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 71 286 5.6E-71 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CSW12_RS08605 685b763cfd8dcd13217c989a2cd5b7dc 289 SUPERFAMILY SSF102405 80 287 2.04E-32 T 29-03-2018 CSW12_RS08605 685b763cfd8dcd13217c989a2cd5b7dc 289 Gene3D G3DSA:3.40.50.450 111 259 3.3E-34 T 29-03-2018 CSW12_RS08605 685b763cfd8dcd13217c989a2cd5b7dc 289 Pfam PF02481 DNA recombination-mediator protein A 71 278 2.8E-75 T 29-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CSW12_RS10925 36876d10d9dcf7911bbe1d29430a56bd 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 114 9.4E-36 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CSW12_RS10925 36876d10d9dcf7911bbe1d29430a56bd 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.128 T 29-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CSW12_RS10925 36876d10d9dcf7911bbe1d29430a56bd 131 SUPERFAMILY SSF52833 1 125 3.79E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS10925 36876d10d9dcf7911bbe1d29430a56bd 131 Pfam PF03960 ArsC family 31 113 6.1E-22 T 29-03-2018 IPR006660 Arsenate reductase-like CSW12_RS10925 36876d10d9dcf7911bbe1d29430a56bd 131 Gene3D G3DSA:3.40.30.10 1 131 2.7E-34 T 29-03-2018 CSW12_RS23770 922e63ade6f86ab45c7cef23bc4c02cf 56 Pfam PF12669 Virus attachment protein p12 family 4 46 5.6E-11 T 29-03-2018 CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 Pfam PF05239 PRC-barrel domain 97 170 1.1E-14 T 29-03-2018 IPR027275 PRC-barrel domain CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 170 24.865 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 SUPERFAMILY SSF50346 100 170 2.43E-21 T 29-03-2018 IPR011033 PRC-barrel-like CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 170 6.6E-54 T 29-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 Gene3D G3DSA:2.30.30.240 96 165 2.9E-22 T 29-03-2018 CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 Pfam PF01782 RimM N-terminal domain 7 91 3.8E-23 T 29-03-2018 IPR002676 RimM protein GO:0006364 CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 Gene3D G3DSA:2.40.30.60 2 95 6.4E-25 T 29-03-2018 IPR002676 RimM protein GO:0006364 CSW12_RS08565 97b091df03da9b7fec46ac4a5306a916 171 SUPERFAMILY SSF50447 3 92 1.66E-21 T 29-03-2018 IPR009000 Translation protein, beta-barrel domain CSW12_RS21425 d64d16b0d5f7b21f25a06162df4e61ca 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 124 2.8E-11 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS21425 d64d16b0d5f7b21f25a06162df4e61ca 285 SUPERFAMILY SSF54593 2 156 2.55E-36 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS21425 d64d16b0d5f7b21f25a06162df4e61ca 285 SUPERFAMILY SSF54593 167 278 7.7E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS21425 d64d16b0d5f7b21f25a06162df4e61ca 285 Gene3D G3DSA:3.10.180.10 63 225 6.3E-32 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS21425 d64d16b0d5f7b21f25a06162df4e61ca 285 Gene3D G3DSA:3.10.180.10 4 62 1.2E-6 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 SUPERFAMILY SSF56801 3 514 4.32E-147 T 29-03-2018 CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 Pfam PF00501 AMP-binding enzyme 12 418 2.8E-100 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 503 7.8E-20 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 Gene3D G3DSA:3.40.50.980 173 322 6.0E-43 T 29-03-2018 CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 Gene3D G3DSA:3.40.50.980 2 172 1.2E-41 T 29-03-2018 CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 Gene3D G3DSA:2.30.38.10 323 411 6.4E-24 T 29-03-2018 CSW12_RS03725 a66171ed66f3d452828d2367b06d1671 518 Gene3D G3DSA:3.30.300.30 412 518 6.6E-30 T 29-03-2018 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 140 156 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 341 1.8E-124 T 29-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 SUPERFAMILY SSF51726 4 343 1.31E-104 T 29-03-2018 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 8 340 4.7E-126 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 Gene3D G3DSA:3.20.20.210 4 344 1.0E-94 T 29-03-2018 CSW12_RS04665 f507cbc6ada959eab885f73351e14c3c 348 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 342 47.209 T 29-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CSW12_RS23920 5bffb7a7914a13477393f549d1c7e94a 651 PIRSF PIRSF018968 1 649 2.4E-123 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS23920 5bffb7a7914a13477393f549d1c7e94a 651 Pfam PF02687 FtsX-like permease family 84 168 1.4E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 PIRSF PIRSF005485 1 338 4.5E-125 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 Gene3D G3DSA:1.10.10.10 1 84 9.6E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 332 5.6E-114 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 SUPERFAMILY SSF55781 71 336 1.77E-67 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 329 32.878 T 29-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 Gene3D G3DSA:3.30.450.40 184 338 5.7E-38 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 Pfam PF01628 HrcA protein C terminal domain 104 322 3.0E-64 T 29-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CSW12_RS21200 0a82df0cfea57ad9f6e4f025999d4f10 338 SUPERFAMILY SSF46785 1 82 3.4E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00460 754a9e238dec672e953a3f799059f091 107 SUPERFAMILY SSF103481 6 105 2.22E-17 T 29-03-2018 CSW12_RS00460 754a9e238dec672e953a3f799059f091 107 Pfam PF00893 Small Multidrug Resistance protein 3 93 6.5E-25 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CSW12_RS28275 63273920aa84377b6513e4c7bea7cc53 493 Pfam PF07949 YbbR-like protein 335 416 1.1E-6 T 29-03-2018 IPR012505 YbbR-like CSW12_RS28275 63273920aa84377b6513e4c7bea7cc53 493 Pfam PF07949 YbbR-like protein 142 225 1.7E-11 T 29-03-2018 IPR012505 YbbR-like CSW12_RS28275 63273920aa84377b6513e4c7bea7cc53 493 Pfam PF07949 YbbR-like protein 240 319 3.9E-17 T 29-03-2018 IPR012505 YbbR-like CSW12_RS28275 63273920aa84377b6513e4c7bea7cc53 493 Pfam PF07949 YbbR-like protein 54 132 3.0E-10 T 29-03-2018 IPR012505 YbbR-like CSW12_RS28275 63273920aa84377b6513e4c7bea7cc53 493 Gene3D G3DSA:2.130.10.10 79 492 7.3E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS12985 158ac1e6909d9689bcfde11f5a4d2ad4 318 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 36 49 - T 29-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CSW12_RS12985 158ac1e6909d9689bcfde11f5a4d2ad4 318 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 298 5.3E-41 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS12985 158ac1e6909d9689bcfde11f5a4d2ad4 318 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CSW12_RS12985 158ac1e6909d9689bcfde11f5a4d2ad4 318 Gene3D G3DSA:3.40.50.1100 21 134 1.0E-22 T 29-03-2018 CSW12_RS12985 158ac1e6909d9689bcfde11f5a4d2ad4 318 Gene3D G3DSA:3.40.50.1100 135 312 1.4E-25 T 29-03-2018 CSW12_RS12985 158ac1e6909d9689bcfde11f5a4d2ad4 318 SUPERFAMILY SSF53686 6 302 3.54E-58 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS06030 2550f50aa50cca5ee3e8a8c6cb191244 371 SUPERFAMILY SSF46689 259 335 1.47E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS06030 2550f50aa50cca5ee3e8a8c6cb191244 371 Gene3D G3DSA:3.30.70.270 168 263 4.6E-4 T 29-03-2018 CSW12_RS06030 2550f50aa50cca5ee3e8a8c6cb191244 371 Pfam PF13556 PucR C-terminal helix-turn-helix domain 301 358 8.0E-20 T 29-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CSW12_RS06030 2550f50aa50cca5ee3e8a8c6cb191244 371 Pfam PF05651 Putative sugar diacid recognition 5 135 2.2E-48 T 29-03-2018 IPR008599 Putative sugar diacid recognition CSW12_RS06030 2550f50aa50cca5ee3e8a8c6cb191244 371 Gene3D G3DSA:1.10.10.60 281 338 2.0E-9 T 29-03-2018 CSW12_RS04895 ca18d66a59977f50e73bfc33833f19f0 210 Pfam PF00395 S-layer homology domain 30 72 8.7E-8 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04895 ca18d66a59977f50e73bfc33833f19f0 210 Pfam PF00395 S-layer homology domain 150 193 1.2E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04895 ca18d66a59977f50e73bfc33833f19f0 210 Pfam PF00395 S-layer homology domain 90 134 2.3E-13 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS19005 3e1251c07536c8940cc76401a83c6577 395 SUPERFAMILY SSF52540 2 309 6.24E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19005 3e1251c07536c8940cc76401a83c6577 395 Gene3D G3DSA:3.40.50.300 1 228 3.0E-54 T 29-03-2018 CSW12_RS19005 3e1251c07536c8940cc76401a83c6577 395 SMART SM00833 256 371 2.2E-52 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS19005 3e1251c07536c8940cc76401a83c6577 395 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 209 8.7E-58 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CSW12_RS19005 3e1251c07536c8940cc76401a83c6577 395 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 371 8.9E-28 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS19005 3e1251c07536c8940cc76401a83c6577 395 Gene3D G3DSA:3.30.1220.10 239 372 6.7E-33 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS08230 6393c0cf65b2738ddcb179637986235b 308 PIRSF PIRSF018571 4 302 3.4E-94 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CSW12_RS08230 6393c0cf65b2738ddcb179637986235b 308 Pfam PF03419 Sporulation factor SpoIIGA 5 299 1.2E-88 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CSW12_RS08230 6393c0cf65b2738ddcb179637986235b 308 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 5 300 1.8E-118 T 29-03-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 CSW12_RS25710 b8bb7ccdfda04a0ce48722a1af683e32 280 SUPERFAMILY SSF82549 1 280 8.37E-97 T 29-03-2018 CSW12_RS25710 b8bb7ccdfda04a0ce48722a1af683e32 280 Gene3D G3DSA:3.40.50.10170 1 151 3.4E-49 T 29-03-2018 CSW12_RS25710 b8bb7ccdfda04a0ce48722a1af683e32 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 3.8E-106 T 29-03-2018 IPR003797 DegV CSW12_RS25710 b8bb7ccdfda04a0ce48722a1af683e32 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 3.1E-99 T 29-03-2018 IPR003797 DegV CSW12_RS25710 b8bb7ccdfda04a0ce48722a1af683e32 280 Gene3D G3DSA:3.30.1180.10 152 280 6.1E-40 T 29-03-2018 CSW12_RS09750 bd6000724a59040725791cbce9c8da57 137 SUPERFAMILY SSF51735 9 136 6.4E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS09750 bd6000724a59040725791cbce9c8da57 137 Pfam PF13380 CoA binding domain 19 133 4.0E-38 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CSW12_RS09750 bd6000724a59040725791cbce9c8da57 137 SMART SM00881 15 107 1.1E-19 T 29-03-2018 IPR003781 CoA-binding GO:0048037 CSW12_RS09750 bd6000724a59040725791cbce9c8da57 137 Gene3D G3DSA:3.40.50.720 15 137 1.6E-31 T 29-03-2018 CSW12_RS06625 10aae2f24c3cd6a57763c8bf11c3a646 239 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 231 2.1E-86 T 29-03-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CSW12_RS06625 10aae2f24c3cd6a57763c8bf11c3a646 239 SUPERFAMILY SSF51366 1 235 2.49E-73 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS06625 10aae2f24c3cd6a57763c8bf11c3a646 239 Pfam PF00977 Histidine biosynthesis protein 2 227 7.6E-78 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CSW12_RS06625 10aae2f24c3cd6a57763c8bf11c3a646 239 Gene3D G3DSA:3.20.20.70 1 238 7.7E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS06625 10aae2f24c3cd6a57763c8bf11c3a646 239 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 235 35.987 T 29-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 439 1.7E-153 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 Pfam PF01235 Sodium:alanine symporter family 56 451 2.9E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 184 202 6.4E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 348 370 6.4E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 303 321 6.4E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 212 231 6.4E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 94 116 6.4E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25045 45833aca8846d0b387a5ec8b1355f479 477 PRINTS PR00175 Sodium/alanine symporter signature 408 428 6.4E-59 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS04495 ac09fe3d3d757015f7cd789ece87cb7f 778 Pfam PF13538 UvrD-like helicase C-terminal domain 706 753 9.1E-9 T 29-03-2018 IPR027785 UvrD-like helicase C-terminal domain CSW12_RS04495 ac09fe3d3d757015f7cd789ece87cb7f 778 Pfam PF13245 AAA domain 214 579 5.0E-11 T 29-03-2018 CSW12_RS04495 ac09fe3d3d757015f7cd789ece87cb7f 778 Gene3D G3DSA:3.40.50.300 604 775 8.3E-27 T 29-03-2018 CSW12_RS04495 ac09fe3d3d757015f7cd789ece87cb7f 778 SUPERFAMILY SSF52540 201 357 3.45E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04495 ac09fe3d3d757015f7cd789ece87cb7f 778 SUPERFAMILY SSF52540 492 758 3.45E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04495 ac09fe3d3d757015f7cd789ece87cb7f 778 Gene3D G3DSA:3.40.50.300 208 595 8.7E-34 T 29-03-2018 CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 SUPERFAMILY SSF56601 290 688 2.41E-69 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 Gene3D G3DSA:3.90.1310.10 30 316 1.5E-36 T 29-03-2018 CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 Gene3D G3DSA:3.40.710.10 317 697 1.0E-79 T 29-03-2018 CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 Pfam PF00905 Penicillin binding protein transpeptidase domain 347 680 4.4E-69 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 302 2.7E-35 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 SUPERFAMILY SSF56519 58 119 8.11E-34 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS20975 98e8c43caaf54df201c937b1c98d580b 709 SUPERFAMILY SSF56519 185 316 8.11E-34 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS26645 aaa0ad35ddd86589542115e6a78fdc61 135 Gene3D G3DSA:1.10.1660.10 58 134 2.2E-11 T 29-03-2018 CSW12_RS26645 aaa0ad35ddd86589542115e6a78fdc61 135 SUPERFAMILY SSF46955 1 121 2.93E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS26645 aaa0ad35ddd86589542115e6a78fdc61 135 SMART SM00422 2 72 7.7E-31 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS26645 aaa0ad35ddd86589542115e6a78fdc61 135 Pfam PF13411 MerR HTH family regulatory protein 2 70 3.4E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS26645 aaa0ad35ddd86589542115e6a78fdc61 135 Gene3D G3DSA:1.10.1660.10 1 57 2.5E-21 T 29-03-2018 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 SUPERFAMILY SSF53271 75 309 4.88E-68 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 5.6E-132 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 29-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 1.5E-52 T 29-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 51.753 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 Gene3D G3DSA:3.40.50.2020 155 310 1.7E-41 T 29-03-2018 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 Gene3D G3DSA:3.40.50.2020 7 154 9.5E-70 T 29-03-2018 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 SMART SM01400 10 126 1.4E-82 T 29-03-2018 CSW12_RS27595 6387e58d06a3a50db1ea517e5c8a24b1 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 4.6E-25 T 29-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 Gene3D G3DSA:3.20.80.10 117 288 6.5E-42 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 SUPERFAMILY SSF55136 128 290 2.88E-31 T 29-03-2018 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 58 100 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 SUPERFAMILY SSF46689 6 55 9.41E-8 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 SMART SM00871 128 288 6.0E-35 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 SUPERFAMILY SSF46689 57 113 3.23E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 Gene3D G3DSA:1.10.10.60 60 116 8.2E-11 T 29-03-2018 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 Pfam PF12833 Helix-turn-helix domain 28 105 7.3E-17 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 SMART SM00342 21 104 2.4E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 Gene3D G3DSA:1.10.10.60 4 59 5.2E-10 T 29-03-2018 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 Pfam PF06445 GyrI-like small molecule binding domain 128 287 1.9E-30 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 73 88 3.5E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS23875 809e43fd351f74145cb28f2797674165 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 88 104 3.5E-6 T 29-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Pfam PF00137 ATP synthase subunit C 6 68 2.1E-15 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 SUPERFAMILY SSF81333 2 71 6.28E-21 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 ProSitePatterns PS00605 ATP synthase c subunit signature. 35 56 - T 29-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 16 70 8.9E-24 T 29-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 7 26 1.4E-20 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 45 70 1.4E-20 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 PRINTS PR00124 ATP synthase C subunit signature 28 43 1.4E-20 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Hamap MF_01396 ATP synthase subunit c [atpH]. 5 70 16.107 T 29-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26330 cf1e8b5bebfc95161e321eb0aabaf5f3 72 Gene3D G3DSA:1.20.20.10 2 71 1.1E-20 T 29-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CSW12_RS01185 22fc573034ea42d5e0aaef0e70aa95f1 270 Hamap MF_01114 Regulatory protein RecX [recX]. 46 213 15.866 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CSW12_RS01185 22fc573034ea42d5e0aaef0e70aa95f1 270 Pfam PF02631 RecX family 88 210 3.0E-26 T 29-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CSW12_RS01185 22fc573034ea42d5e0aaef0e70aa95f1 270 Gene3D G3DSA:1.10.10.10 113 156 9.5E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01185 22fc573034ea42d5e0aaef0e70aa95f1 270 Gene3D G3DSA:1.10.10.10 47 111 6.5E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01185 22fc573034ea42d5e0aaef0e70aa95f1 270 Gene3D G3DSA:1.10.10.10 219 265 5.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01185 22fc573034ea42d5e0aaef0e70aa95f1 270 Gene3D G3DSA:1.10.10.10 162 211 2.7E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21930 14d6eff7a9b5b116724df1f8cb28c899 341 Gene3D G3DSA:3.30.200.20 4 96 2.2E-11 T 29-03-2018 CSW12_RS21930 14d6eff7a9b5b116724df1f8cb28c899 341 Gene3D G3DSA:3.90.1200.10 97 334 2.4E-16 T 29-03-2018 CSW12_RS21930 14d6eff7a9b5b116724df1f8cb28c899 341 SUPERFAMILY SSF56112 12 307 5.1E-22 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS21930 14d6eff7a9b5b116724df1f8cb28c899 341 Pfam PF01636 Phosphotransferase enzyme family 33 245 5.2E-8 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS21930 14d6eff7a9b5b116724df1f8cb28c899 341 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 9 320 1.8E-135 T 29-03-2018 IPR014253 Spore coat protein YsxE CSW12_RS04070 6709bda78dd1726b5946db0347a01979 179 Pfam PF11611 Domain of unknown function (DUF4352) 73 168 6.8E-16 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 CSW12_RS04070 6709bda78dd1726b5946db0347a01979 179 Gene3D G3DSA:2.60.40.1240 32 175 1.3E-14 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS27925 a8b7f44ad6c48ade403a9e0f8e205173 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 29-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS27925 a8b7f44ad6c48ade403a9e0f8e205173 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 26 143 0.002 T 29-03-2018 CSW12_RS27925 a8b7f44ad6c48ade403a9e0f8e205173 166 SUPERFAMILY SSF160369 5 160 1.22E-54 T 29-03-2018 CSW12_RS27925 a8b7f44ad6c48ade403a9e0f8e205173 166 Pfam PF00466 Ribosomal protein L10 6 100 2.0E-29 T 29-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CSW12_RS27925 a8b7f44ad6c48ade403a9e0f8e205173 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.24 T 29-03-2018 IPR022973 Ribosomal protein L10 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.6E-102 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 4.0E-81 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 SUPERFAMILY SSF53335 3 228 3.19E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.5 T 29-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 2.4E-135 T 29-03-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 29-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CSW12_RS20035 140b18a2ec1be0fe31ee8b91e0304b45 237 Gene3D G3DSA:3.40.50.150 1 232 1.6E-43 T 29-03-2018 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 PIRSF PIRSF000124 5 412 3.3E-65 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 6 187 8.7E-40 T 29-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 PIRSF PIRSF500136 1 414 7.1E-151 T 29-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 SUPERFAMILY SSF51735 6 196 3.23E-39 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Gene3D G3DSA:1.20.5.170 205 225 2.7E-11 T 29-03-2018 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Gene3D G3DSA:3.40.50.720 2 202 7.2E-36 T 29-03-2018 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 296 1.7E-26 T 29-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Gene3D G3DSA:3.40.50.720 312 413 6.5E-19 T 29-03-2018 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Gene3D G3DSA:1.10.1040.10 226 302 3.3E-29 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 SUPERFAMILY SSF52413 314 410 1.96E-18 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 SMART SM00984 317 411 2.1E-28 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 410 1.6E-19 T 29-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 6 406 5.8E-135 T 29-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CSW12_RS01130 fdca51a132e6a8b5aaef2d8c640100e6 414 SUPERFAMILY SSF48179 205 298 1.33E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 Gene3D G3DSA:3.10.150.10 254 376 1.0E-20 T 29-03-2018 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 374 6.7E-24 T 29-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 374 2.0E-91 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 126 2.1E-26 T 29-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 Gene3D G3DSA:3.10.150.10 1 128 2.2E-22 T 29-03-2018 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 Gene3D G3DSA:3.10.150.10 129 253 9.9E-32 T 29-03-2018 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 SUPERFAMILY SSF55979 132 248 2.83E-27 T 29-03-2018 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 PIRSF PIRSF000804 1 376 1.9E-94 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 SMART SM00480 17 371 1.5E-107 T 29-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 SUPERFAMILY SSF55979 251 374 9.11E-23 T 29-03-2018 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 248 2.4E-32 T 29-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS14260 85b03392758d68d1f52f7bc22cc69b2d 376 SUPERFAMILY SSF55979 1 126 1.42E-22 T 29-03-2018 CSW12_RS04830 edca6760a98c797f043848e7d018a687 374 Pfam PF13800 Sigma factor regulator N-terminal 65 153 1.5E-20 T 29-03-2018 IPR029101 Sigma factor regulator, N-terminal CSW12_RS04830 edca6760a98c797f043848e7d018a687 374 Pfam PF13791 Sigma factor regulator C-terminal 207 364 4.5E-40 T 29-03-2018 IPR025672 Sigma factor regulator C-terminal domain CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 Gene3D G3DSA:3.30.420.40 248 496 6.9E-78 T 29-03-2018 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 Hamap MF_00186 Glycerol kinase [glpK]. 2 496 59.906 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 361 381 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 PIRSF PIRSF000538 2 496 1.3E-183 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 493 1.2E-228 T 29-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 SUPERFAMILY SSF53067 254 491 4.66E-86 T 29-03-2018 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 SUPERFAMILY SSF53067 3 254 3.97E-99 T 29-03-2018 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 449 1.5E-63 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 251 1.4E-92 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CSW12_RS04465 7abfa257b77ccbe8f6d1c75ce6159239 496 Gene3D G3DSA:3.30.420.40 1 247 1.8E-90 T 29-03-2018 CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 SMART SM00862 154 231 1.3E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 SUPERFAMILY SSF46894 129 232 1.39E-27 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 231 9.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 SMART SM00448 4 115 1.3E-39 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 SUPERFAMILY SSF52172 3 126 5.41E-37 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 Pfam PF00072 Response regulator receiver domain 6 115 4.3E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 Gene3D G3DSA:1.10.10.10 128 234 2.4E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04860 e3d08b9f02c0956db6c6c293c35b8e55 234 Gene3D G3DSA:3.40.50.2300 2 127 2.9E-33 T 29-03-2018 CSW12_RS14755 d78a8aa8e237fdf2446efd426a98986d 304 Pfam PF03069 Acetamidase/Formamidase family 15 141 1.4E-13 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CSW12_RS14755 d78a8aa8e237fdf2446efd426a98986d 304 Pfam PF03069 Acetamidase/Formamidase family 147 276 2.5E-20 T 29-03-2018 IPR004304 Acetamidase/Formamidase GO:0016811 CSW12_RS14755 d78a8aa8e237fdf2446efd426a98986d 304 Gene3D G3DSA:3.10.28.20 215 292 2.0E-19 T 29-03-2018 CSW12_RS14755 d78a8aa8e237fdf2446efd426a98986d 304 Gene3D G3DSA:2.60.120.580 1 211 1.7E-54 T 29-03-2018 CSW12_RS14755 d78a8aa8e237fdf2446efd426a98986d 304 SUPERFAMILY SSF141130 2 290 3.14E-88 T 29-03-2018 CSW12_RS10265 2533b35914c48f320854eba873f7ce7f 688 SUPERFAMILY SSF53448 56 291 4.22E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10265 2533b35914c48f320854eba873f7ce7f 688 SUPERFAMILY SSF53448 372 653 7.03E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10265 2533b35914c48f320854eba873f7ce7f 688 Gene3D G3DSA:3.90.550.10 55 345 1.2E-13 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10265 2533b35914c48f320854eba873f7ce7f 688 Gene3D G3DSA:3.90.550.10 369 672 5.2E-18 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 Gene3D G3DSA:1.10.8.50 1 66 6.1E-25 T 29-03-2018 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 Gene3D G3DSA:4.10.910.10 67 85 4.7E-19 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 29-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 PIRSF PIRSF002134 1 121 6.3E-42 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 28.344 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 Gene3D G3DSA:4.10.910.10 86 121 1.2E-26 T 29-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 SUPERFAMILY SSF46946 2 120 1.44E-44 T 29-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.3E-52 T 29-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28110 5a5ac4b79e6fbc309aa47345e607ddff 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.4E-32 T 29-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 394 8.0E-174 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 Gene3D G3DSA:1.20.5.470 363 395 3.6E-10 T 29-03-2018 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 Gene3D G3DSA:3.90.1260.10 158 352 3.9E-86 T 29-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 Pfam PF00764 Arginosuccinate synthase 7 391 9.6E-180 T 29-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 Gene3D G3DSA:3.40.50.620 4 157 1.4E-27 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 SUPERFAMILY SSF69864 170 397 1.44E-95 T 29-03-2018 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 29-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 SUPERFAMILY SSF52402 1 170 2.21E-47 T 29-03-2018 CSW12_RS22770 53a386115004d5b56e97d508496befc7 401 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 396 54.487 T 29-03-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CSW12_RS15770 44d4a8fda69692a9d176fb15c19ad207 358 Pfam PF05816 Toxic anion resistance protein (TelA) 46 353 2.2E-54 T 29-03-2018 IPR008863 Toxic anion resistance CSW12_RS15770 44d4a8fda69692a9d176fb15c19ad207 358 PIRSF PIRSF026508 1 358 3.5E-96 T 29-03-2018 IPR008863 Toxic anion resistance CSW12_RS05550 b0ceaa55fef51fc5af3d5eea87ff0ced 292 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 34 290 7.5E-76 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS05550 b0ceaa55fef51fc5af3d5eea87ff0ced 292 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS05550 b0ceaa55fef51fc5af3d5eea87ff0ced 292 Gene3D G3DSA:3.30.2350.10 77 292 8.7E-67 T 29-03-2018 CSW12_RS05550 b0ceaa55fef51fc5af3d5eea87ff0ced 292 Pfam PF00849 RNA pseudouridylate synthase 86 236 1.2E-29 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS05550 b0ceaa55fef51fc5af3d5eea87ff0ced 292 SUPERFAMILY SSF55120 70 290 2.88E-71 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS19875 30c6d8dec4507e18e2c891383c5375bd 56 PIRSF PIRSF036698 1 56 7.2E-38 T 29-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA CSW12_RS19875 30c6d8dec4507e18e2c891383c5375bd 56 Pfam PF14084 Protein of unknown function (DUF4264) 4 56 6.3E-25 T 29-03-2018 IPR012190 Uncharacterised conserved protein UCP036698, YpmA CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 352 360 - T 29-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PIRSF PIRSF038927 1 665 0.0 T 29-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 Pfam PF06628 Catalase-related immune-responsive 438 499 3.1E-17 T 29-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 SUPERFAMILY SSF56634 10 526 4.71E-229 T 29-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 Pfam PF00199 Catalase 22 407 2.3E-187 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 Gene3D G3DSA:2.40.180.10 1 377 1.1E-172 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 SMART SM01060 22 410 8.7E-285 T 29-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PRINTS PR00067 Catalase signature 339 365 3.2E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PRINTS PR00067 Catalase signature 138 156 3.2E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PRINTS PR00067 Catalase signature 98 116 3.2E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PRINTS PR00067 Catalase signature 307 334 3.2E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PRINTS PR00067 Catalase signature 35 58 3.2E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS03555 f3b43d13bbafbd04b247792ce243a317 665 PRINTS PR00067 Catalase signature 119 136 3.2E-71 T 29-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CSW12_RS04685 06656eb55f29a294a3f49202f73e08d4 788 Gene3D G3DSA:2.40.50.200 221 336 6.4E-4 T 29-03-2018 CSW12_RS04685 06656eb55f29a294a3f49202f73e08d4 788 Gene3D G3DSA:2.60.40.10 156 220 1.6E-11 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS04685 06656eb55f29a294a3f49202f73e08d4 788 SUPERFAMILY SSF56219 486 786 2.75E-32 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS04685 06656eb55f29a294a3f49202f73e08d4 788 Gene3D G3DSA:3.60.10.10 491 783 6.4E-33 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS04685 06656eb55f29a294a3f49202f73e08d4 788 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 494 775 7.7E-9 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS04685 06656eb55f29a294a3f49202f73e08d4 788 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 156 222 4.9E-18 T 29-03-2018 CSW12_RS02125 b959b7e2a8425a27df0122c8e74fc820 40 Pfam PF13137 Protein of unknown function (DUF3983) 5 38 5.0E-14 T 29-03-2018 IPR025041 Protein of unknown function DUF3983 CSW12_RS18985 28af251479cea71e813c9c8b951f45ac 219 SUPERFAMILY SSF53335 25 192 4.57E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS18985 28af251479cea71e813c9c8b951f45ac 219 Gene3D G3DSA:3.40.50.150 21 190 5.4E-9 T 29-03-2018 CSW12_RS18985 28af251479cea71e813c9c8b951f45ac 219 Pfam PF13578 Methyltransferase domain 45 161 1.6E-23 T 29-03-2018 CSW12_RS18935 9ca1e02e31c8b78aa876e62bbffe9dcf 135 Pfam PF13078 Protein of unknown function (DUF3942) 8 132 6.6E-63 T 29-03-2018 IPR025074 Protein of unknown function DUF3942 CSW12_RS05520 b9e91c9ba46bd3c1d5b8f41463c44a91 297 Pfam PF13743 Thioredoxin 25 219 2.3E-73 T 29-03-2018 CSW12_RS05520 b9e91c9ba46bd3c1d5b8f41463c44a91 297 SUPERFAMILY SSF52833 22 227 5.03E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS05520 b9e91c9ba46bd3c1d5b8f41463c44a91 297 Gene3D G3DSA:3.40.30.10 18 232 1.7E-17 T 29-03-2018 CSW12_RS21315 7db0b7e691aa4271a066a5c5d4aa61e6 46 Gene3D G3DSA:1.10.287.1100 4 36 3.2E-16 T 29-03-2018 IPR015064 Sporulation inhibitor A CSW12_RS21315 7db0b7e691aa4271a066a5c5d4aa61e6 46 Pfam PF08970 Sporulation inhibitor A 1 42 1.1E-18 T 29-03-2018 IPR015064 Sporulation inhibitor A CSW12_RS21315 7db0b7e691aa4271a066a5c5d4aa61e6 46 SUPERFAMILY SSF100985 1 44 2.88E-16 T 29-03-2018 IPR015064 Sporulation inhibitor A CSW12_RS03775 647771c3533f1d87d256e60212d6a75b 262 Gene3D G3DSA:1.10.12.10 220 262 8.1E-16 T 29-03-2018 IPR014748 Crontonase, C-terminal CSW12_RS03775 647771c3533f1d87d256e60212d6a75b 262 SUPERFAMILY SSF52096 6 261 9.79E-64 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS03775 647771c3533f1d87d256e60212d6a75b 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 6.5E-50 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CSW12_RS03775 647771c3533f1d87d256e60212d6a75b 262 Gene3D G3DSA:3.90.226.10 9 219 1.0E-53 T 29-03-2018 CSW12_RS18520 b8fac4beb5eba63fa14cb60245f2012a 534 PIRSF PIRSF002741 1 534 6.6E-109 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS18520 b8fac4beb5eba63fa14cb60245f2012a 534 Gene3D G3DSA:3.10.105.10 298 502 2.0E-47 T 29-03-2018 CSW12_RS18520 b8fac4beb5eba63fa14cb60245f2012a 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 452 5.3E-77 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS18520 b8fac4beb5eba63fa14cb60245f2012a 534 Gene3D G3DSA:3.90.76.10 52 162 1.1E-31 T 29-03-2018 CSW12_RS18520 b8fac4beb5eba63fa14cb60245f2012a 534 SUPERFAMILY SSF53850 26 528 9.41E-127 T 29-03-2018 CSW12_RS18520 b8fac4beb5eba63fa14cb60245f2012a 534 Gene3D G3DSA:3.40.190.10 163 297 8.4E-36 T 29-03-2018 CSW12_RS16525 09e7a77b06cc20ddf77b6e651571a08e 130 SUPERFAMILY SSF160515 4 127 1.7E-39 T 29-03-2018 CSW12_RS16525 09e7a77b06cc20ddf77b6e651571a08e 130 Pfam PF07997 Protein of unknown function (DUF1694) 4 119 6.5E-39 T 29-03-2018 IPR012543 Protein of unknown function DUF1694 CSW12_RS16525 09e7a77b06cc20ddf77b6e651571a08e 130 Gene3D G3DSA:3.30.1330.30 4 123 1.5E-42 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS16525 09e7a77b06cc20ddf77b6e651571a08e 130 PIRSF PIRSF034303 1 130 2.1E-49 T 29-03-2018 IPR012543 Protein of unknown function DUF1694 CSW12_RS23255 1bdebf3c02b0d96dbf33aeb80f331071 60 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 6.0E-27 T 29-03-2018 IPR020296 Sporulation protein Cse60 CSW12_RS23255 1bdebf3c02b0d96dbf33aeb80f331071 60 Pfam PF10957 Sporulation protein Cse60 1 60 4.8E-35 T 29-03-2018 IPR020296 Sporulation protein Cse60 CSW12_RS23420 d32a5077eb62002472e3cbde259b7908 253 Gene3D G3DSA:3.40.50.300 1 247 4.7E-65 T 29-03-2018 CSW12_RS23420 d32a5077eb62002472e3cbde259b7908 253 SUPERFAMILY SSF52540 6 227 2.3E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS23420 d32a5077eb62002472e3cbde259b7908 253 Pfam PF00005 ABC transporter 26 174 1.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS23420 d32a5077eb62002472e3cbde259b7908 253 SMART SM00382 35 234 1.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.3E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.3E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.3E-25 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 Pfam PF00203 Ribosomal protein S19 3 83 4.0E-36 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 SUPERFAMILY SSF54570 3 83 9.02E-35 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.013 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 29-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 PIRSF PIRSF002144 1 92 3.7E-32 T 29-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 Gene3D G3DSA:3.30.860.10 1 92 2.6E-40 T 29-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28005 1905e41a7c02e04d00ea435ec0fe19c1 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 8.0E-47 T 29-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 SMART SM00116 98 148 2.1E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 SMART SM00116 161 209 7.3E-9 T 29-03-2018 IPR000644 CBS domain CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 PIRSF PIRSF000130 1 487 1.1E-210 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 7.0E-201 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 1.8E-167 T 29-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 Pfam PF00571 CBS domain 153 204 6.1E-8 T 29-03-2018 IPR000644 CBS domain CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 Pfam PF00571 CBS domain 97 144 3.4E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 SMART SM01240 9 474 0.0 T 29-03-2018 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 SUPERFAMILY SSF54631 66 208 8.21E-32 T 29-03-2018 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 SUPERFAMILY SSF51412 5 92 6.02E-126 T 29-03-2018 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 SUPERFAMILY SSF51412 220 478 6.02E-126 T 29-03-2018 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 29-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 87.281 T 29-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CSW12_RS27370 1a6876b4e3b327f1777d5305273963b2 487 Gene3D G3DSA:3.20.20.70 3 484 8.2E-114 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 235 254 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 344 45.775 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 341 5.8E-125 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 SMART SM01329 4 340 3.3E-178 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 Gene3D G3DSA:3.40.718.10 1 348 1.7E-122 T 29-03-2018 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 SUPERFAMILY SSF53659 2 344 3.24E-117 T 29-03-2018 CSW12_RS06585 dc0b9b521344fb8d7044c362c0f760a0 354 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 343 5.8E-139 T 29-03-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 Gene3D G3DSA:1.10.1060.10 2 112 3.1E-17 T 29-03-2018 CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 SUPERFAMILY SSF46548 9 105 1.48E-19 T 29-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 Pfam PF02754 Cysteine-rich domain 328 413 8.3E-14 T 29-03-2018 IPR004017 Cysteine-rich domain CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 Pfam PF02754 Cysteine-rich domain 197 277 1.4E-19 T 29-03-2018 IPR004017 Cysteine-rich domain CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 Pfam PF13183 4Fe-4S dicluster domain 22 91 1.9E-12 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS06020 9406e27f56d43f66be01891e3e4d3d8a 442 PIRSF PIRSF000139 5 441 6.2E-162 T 29-03-2018 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Gene3D G3DSA:3.40.50.140 3 161 1.4E-27 T 29-03-2018 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 SMART SM00436 133 226 1.3E-24 T 29-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Pfam PF13342 C-terminal repeat of topoisomerase 822 882 7.1E-15 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Pfam PF13342 C-terminal repeat of topoisomerase 643 700 4.2E-15 T 29-03-2018 IPR025589 Topoisomerase C-terminal repeat CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Gene3D G3DSA:1.10.460.10 166 347 6.3E-27 T 29-03-2018 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Gene3D G3DSA:1.10.460.10 472 606 7.3E-12 T 29-03-2018 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 5.3E-16 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 311 320 5.3E-16 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 393 409 5.3E-16 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 512 526 5.3E-16 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 107 120 5.3E-16 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 306 320 - T 29-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Pfam PF01751 Toprim domain 4 140 1.8E-13 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 SMART SM00437 269 549 3.2E-68 T 29-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Pfam PF01131 DNA topoisomerase 160 584 1.3E-83 T 29-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Gene3D G3DSA:2.70.20.10 354 471 6.4E-16 T 29-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Gene3D G3DSA:3.30.65.10 607 661 3.8E-5 T 29-03-2018 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 Gene3D G3DSA:3.30.65.10 691 750 9.7E-5 T 29-03-2018 CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 SMART SM00493 3 133 1.9E-17 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS31040 573f67a11b632ca1694a1d9e14a6d3df 884 SUPERFAMILY SSF56712 3 597 1.96E-130 T 29-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CSW12_RS14255 18afa1c45f20318e56a1dec746977c4e 307 Gene3D G3DSA:2.160.20.10 137 292 2.7E-7 T 29-03-2018 IPR012334 Pectin lyase fold CSW12_RS14255 18afa1c45f20318e56a1dec746977c4e 307 SUPERFAMILY SSF51126 42 247 2.9E-11 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CSW12_RS14255 18afa1c45f20318e56a1dec746977c4e 307 Gene3D G3DSA:2.160.20.10 19 136 4.6E-9 T 29-03-2018 IPR012334 Pectin lyase fold CSW12_RS23930 ddf66af6552877b41137274339419e3f 658 Pfam PF02687 FtsX-like permease family 87 173 1.1E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS23930 ddf66af6552877b41137274339419e3f 658 PIRSF PIRSF018968 1 656 8.1E-119 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 PRINTS PR00050 Cold shock protein signature 5 20 1.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 PRINTS PR00050 Cold shock protein signature 25 34 1.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 PRINTS PR00050 Cold shock protein signature 40 58 1.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 SUPERFAMILY SSF50249 3 66 4.98E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 PIRSF PIRSF002599 1 67 1.1E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 SMART SM00357 4 67 2.8E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 Gene3D G3DSA:2.40.50.140 2 67 7.2E-27 T 29-03-2018 CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CSW12_RS15935 f6b8702516c7cd239dec56f4f2081ff6 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 1.3E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS26155 00bb64a7b9d23d66457b0419b0cba394 247 Pfam PF02706 Chain length determinant protein 3 93 2.6E-20 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CSW12_RS26155 00bb64a7b9d23d66457b0419b0cba394 247 Pfam PF13807 G-rich domain on putative tyrosine kinase 143 194 1.6E-8 T 29-03-2018 IPR032807 Tyrosine kinase, G-rich domain CSW12_RS26155 00bb64a7b9d23d66457b0419b0cba394 247 Gene3D G3DSA:3.30.1890.10 37 150 7.7E-15 T 29-03-2018 CSW12_RS01600 e473c940db4887bb7073fd24dd37d36d 235 SMART SM00448 2 115 8.4E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01600 e473c940db4887bb7073fd24dd37d36d 235 PIRSF PIRSF006171 1 229 9.8E-84 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CSW12_RS01600 e473c940db4887bb7073fd24dd37d36d 235 Gene3D G3DSA:3.40.50.2300 1 156 2.7E-34 T 29-03-2018 CSW12_RS01600 e473c940db4887bb7073fd24dd37d36d 235 SUPERFAMILY SSF52172 1 140 4.7E-36 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS01600 e473c940db4887bb7073fd24dd37d36d 235 Gene3D G3DSA:1.10.10.10 157 221 9.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01600 e473c940db4887bb7073fd24dd37d36d 235 Pfam PF00072 Response regulator receiver domain 4 115 9.6E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS09920 21f0456c5a46132e7c63e0589b118cc9 237 Pfam PF01226 Formate/nitrite transporter 29 226 8.1E-59 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CSW12_RS09920 21f0456c5a46132e7c63e0589b118cc9 237 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 139 149 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CSW12_RS09920 21f0456c5a46132e7c63e0589b118cc9 237 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 55 64 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CSW12_RS09920 21f0456c5a46132e7c63e0589b118cc9 237 Gene3D G3DSA:1.20.1080.10 8 42 0.049 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS09920 21f0456c5a46132e7c63e0589b118cc9 237 Gene3D G3DSA:1.20.1080.10 43 237 4.4E-66 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Gene3D G3DSA:3.30.70.20 26 194 1.3E-4 T 29-03-2018 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Pfam PF13484 4Fe-4S double cluster binding domain 187 250 7.7E-16 T 29-03-2018 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 SMART SM00567 E-Z type HEAT repeats 298 327 89.0 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 SMART SM00567 E-Z type HEAT repeats 330 359 0.0037 T 29-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 SUPERFAMILY SSF48371 295 373 1.82E-10 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Gene3D G3DSA:1.25.40.70 267 377 9.7E-9 T 29-03-2018 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.574 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 SUPERFAMILY SSF54862 164 252 3.56E-17 T 29-03-2018 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Gene3D G3DSA:3.30.70.20 195 266 4.6E-9 T 29-03-2018 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 5.0E-18 T 29-03-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 Pfam PF13646 HEAT repeats 300 365 1.8E-9 T 29-03-2018 CSW12_RS01425 e8eb1363fb0b916f1ed24e8305cba1f5 380 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 9.1E-129 T 29-03-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 CSW12_RS24435 85cb6db4a946e17be2f0517ad707f9b9 415 Gene3D G3DSA:1.20.1250.20 16 213 5.5E-25 T 29-03-2018 CSW12_RS24435 85cb6db4a946e17be2f0517ad707f9b9 415 Gene3D G3DSA:1.20.1250.20 224 413 4.0E-13 T 29-03-2018 CSW12_RS24435 85cb6db4a946e17be2f0517ad707f9b9 415 SUPERFAMILY SSF103473 20 409 5.1E-40 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS24435 85cb6db4a946e17be2f0517ad707f9b9 415 Pfam PF07690 Major Facilitator Superfamily 27 364 6.9E-31 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS08080 f12eb022d06d6c0285123df5e9ff96b5 190 SUPERFAMILY SSF53254 1 188 2.08E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS08080 f12eb022d06d6c0285123df5e9ff96b5 190 PIRSF PIRSF000709 2 79 0.0014 T 29-03-2018 CSW12_RS08080 f12eb022d06d6c0285123df5e9ff96b5 190 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 184 3.1E-44 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS08080 f12eb022d06d6c0285123df5e9ff96b5 190 Gene3D G3DSA:3.40.50.1240 1 190 9.6E-43 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS08080 f12eb022d06d6c0285123df5e9ff96b5 190 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CSW12_RS08080 f12eb022d06d6c0285123df5e9ff96b5 190 SMART SM00855 3 147 1.0E-18 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS02930 b0e1cd91cd11b3eb679293339899ea70 383 Pfam PF13142 Domain of unknown function (DUF3960) 1 89 3.0E-61 T 29-03-2018 IPR025046 Domain of unknown function DUF3960 CSW12_RS02930 b0e1cd91cd11b3eb679293339899ea70 383 Pfam PF13112 Protein of unknown function (DUF3965) 91 381 2.6E-205 T 29-03-2018 IPR025087 Domain of unknown function DUF3965 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 29-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.5E-35 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 1.0E-35 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 1.0E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 1.0E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 1.0E-11 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 Gene3D G3DSA:2.40.50.140 7 84 1.2E-31 T 29-03-2018 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 Pfam PF00366 Ribosomal protein S17 12 79 2.0E-32 T 29-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 24.115 T 29-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28030 8495325af0f263651361c510d44e0665 87 SUPERFAMILY SSF50249 7 84 5.57E-32 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS04225 d4460054f0d66261092cbc19c583d17d 108 Pfam PF03551 Transcriptional regulator PadR-like family 22 89 1.3E-15 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS04225 d4460054f0d66261092cbc19c583d17d 108 Gene3D G3DSA:1.10.10.10 3 98 4.3E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04225 d4460054f0d66261092cbc19c583d17d 108 SUPERFAMILY SSF46785 10 103 1.32E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23635 da91dd544aab69c490638f5d7ede0300 254 SUPERFAMILY SSF52540 4 215 2.53E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS23635 da91dd544aab69c490638f5d7ede0300 254 Pfam PF00005 ABC transporter 23 162 2.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS23635 da91dd544aab69c490638f5d7ede0300 254 SMART SM00382 32 211 3.1E-19 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS23635 da91dd544aab69c490638f5d7ede0300 254 Gene3D G3DSA:3.40.50.300 1 219 2.0E-59 T 29-03-2018 CSW12_RS23635 da91dd544aab69c490638f5d7ede0300 254 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 SMART SM00065 197 326 0.0035 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 SMART SM00065 25 176 9.9E-4 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 SUPERFAMILY SSF55781 28 179 3.27E-19 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 Gene3D G3DSA:3.30.565.10 402 523 7.8E-15 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 SUPERFAMILY SSF55874 403 522 9.45E-12 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 Pfam PF13492 GAF domain 203 318 9.5E-7 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 SUPERFAMILY SSF55781 185 344 2.84E-13 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 Gene3D G3DSA:3.30.450.40 2 172 2.1E-18 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 Gene3D G3DSA:3.30.450.40 185 340 4.5E-14 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 Pfam PF07730 Histidine kinase 333 400 7.7E-21 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS26845 9646a2f86e99b08f6f5533eceeb435b2 523 Pfam PF13185 GAF domain 29 166 6.6E-13 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 Gene3D G3DSA:1.20.140.10 285 477 2.0E-70 T 29-03-2018 CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 SUPERFAMILY SSF47203 261 476 1.65E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 270 6.0E-71 T 29-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 SUPERFAMILY SSF56645 7 271 1.44E-58 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 Gene3D G3DSA:2.40.110.10 143 272 1.8E-14 T 29-03-2018 CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 Gene3D G3DSA:1.10.3140.10 3 142 5.1E-31 T 29-03-2018 CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 PIRSF PIRSF000331 3 477 5.6E-125 T 29-03-2018 IPR004925 HpaB/PvcC/4-BUDH CSW12_RS14820 12b73e7e0afd1347042f99ae0daa7cab 477 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 285 476 2.1E-62 T 29-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 Gene3D G3DSA:3.90.228.20 213 291 2.6E-30 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 Gene3D G3DSA:3.90.228.20 292 526 3.5E-96 T 29-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 SUPERFAMILY SSF68923 8 212 3.49E-81 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 Gene3D G3DSA:3.40.449.10 20 211 2.6E-79 T 29-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 17 526 3.8E-249 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 PIRSF PIRSF006294 3 527 1.2E-246 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 20 481 4.2E-229 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 SUPERFAMILY SSF53795 213 524 2.52E-137 T 29-03-2018 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 29-03-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CSW12_RS23530 89748338c240a4373633b16bd2010f7b 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 528 56.333 T 29-03-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 61 - T 29-03-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 SUPERFAMILY SSF52335 1 128 4.97E-52 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 SMART SM00851 14 107 2.5E-23 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 1 120 6.7E-58 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 PIRSF PIRSF006614 1 131 1.9E-61 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 Pfam PF02142 MGS-like domain 15 107 1.7E-17 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 36.571 T 29-03-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CSW12_RS19930 ef3eea7e2672dbf0e21af0cbd1b11982 131 Gene3D G3DSA:3.40.50.1380 1 131 2.4E-37 T 29-03-2018 IPR011607 Methylglyoxal synthase-like domain CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 Gene3D G3DSA:3.40.50.1860 117 206 1.6E-14 T 29-03-2018 CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 87 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 200 2.2E-39 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 SUPERFAMILY SSF53681 1 112 1.31E-27 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 Gene3D G3DSA:3.40.50.1860 1 116 6.2E-30 T 29-03-2018 CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 219 3.5E-41 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CSW12_RS23455 21a528c80a25766c24fd4bd08d517f9c 220 SUPERFAMILY SSF53681 116 217 2.29E-17 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 Gene3D G3DSA:3.30.70.270 80 179 7.2E-15 T 29-03-2018 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 Pfam PF00817 impB/mucB/samB family 15 167 2.4E-21 T 29-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 SUPERFAMILY SSF56672 10 253 6.23E-46 T 29-03-2018 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 SUPERFAMILY SSF100879 264 360 3.92E-8 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 Gene3D G3DSA:1.10.150.20 183 265 5.0E-17 T 29-03-2018 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 Gene3D G3DSA:3.30.1490.100 266 375 4.5E-15 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS31200 00f82f12084065be8b638cec3997f026 425 Pfam PF11799 impB/mucB/samB family C-terminal domain 258 367 1.7E-11 T 29-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CSW12_RS04920 9f9637098e15d83fee775eaef2fec3e0 263 Pfam PF01636 Phosphotransferase enzyme family 121 181 1.8E-11 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS04920 9f9637098e15d83fee775eaef2fec3e0 263 SUPERFAMILY SSF56112 8 258 1.53E-27 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS04920 9f9637098e15d83fee775eaef2fec3e0 263 Gene3D G3DSA:1.10.510.10 32 206 1.0E-19 T 29-03-2018 CSW12_RS16905 2a19f6f8b7a0c5057a716513ac04eb2e 175 SUPERFAMILY SSF56784 2 173 6.8E-38 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16905 2a19f6f8b7a0c5057a716513ac04eb2e 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 138 8.9E-24 T 29-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CSW12_RS16905 2a19f6f8b7a0c5057a716513ac04eb2e 175 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 134 9.8E-28 T 29-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CSW12_RS16905 2a19f6f8b7a0c5057a716513ac04eb2e 175 PIRSF PIRSF004682 1 172 3.3E-39 T 29-03-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CSW12_RS16905 2a19f6f8b7a0c5057a716513ac04eb2e 175 Pfam PF13242 HAD-hyrolase-like 91 167 1.4E-17 T 29-03-2018 CSW12_RS16905 2a19f6f8b7a0c5057a716513ac04eb2e 175 Gene3D G3DSA:3.40.50.1000 4 175 2.6E-31 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS12600 590f043a1af220a2401b317c6a79ccb9 485 Gene3D G3DSA:1.20.1250.20 251 449 2.4E-25 T 29-03-2018 CSW12_RS12600 590f043a1af220a2401b317c6a79ccb9 485 SUPERFAMILY SSF103473 20 443 2.22E-74 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12600 590f043a1af220a2401b317c6a79ccb9 485 Gene3D G3DSA:1.20.1250.20 21 238 2.3E-27 T 29-03-2018 CSW12_RS12600 590f043a1af220a2401b317c6a79ccb9 485 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS12600 590f043a1af220a2401b317c6a79ccb9 485 Pfam PF07690 Major Facilitator Superfamily 57 380 8.8E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS04230 d7057f9ab1c080aa54473a6b401d3f61 203 Pfam PF11193 Protein of unknown function (DUF2812) 10 118 5.5E-30 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 SUPERFAMILY SSF54826 1 125 3.25E-37 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 SMART SM00922 142 239 2.4E-27 T 29-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 Gene3D G3DSA:3.20.20.120 128 369 1.7E-62 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 SUPERFAMILY SSF51604 112 363 7.47E-69 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 Pfam PF13378 Enolase C-terminal domain-like 145 356 2.1E-48 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 Gene3D G3DSA:3.30.390.10 1 127 3.7E-39 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS00525 1b704d8bca138cae11e5a1449b306f00 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 12 124 2.9E-24 T 29-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CSW12_RS09675 e0a281f078e896040f255818504900fb 907 SUPERFAMILY SSF52016 640 898 1.84E-87 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CSW12_RS09675 e0a281f078e896040f255818504900fb 907 Pfam PF00694 Aconitase C-terminal domain 701 828 2.6E-46 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 Gene3D G3DSA:3.40.1060.10 242 374 1.7E-44 T 29-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 219 234 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 440 451 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 147 160 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 502 515 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 375 389 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 281 294 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 171 179 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 295 308 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 PRINTS PR00415 Aconitase family signature 205 218 1.3E-39 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 Pfam PF00330 Aconitase family (aconitate hydratase) 77 571 3.2E-176 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 29-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 Gene3D G3DSA:3.30.499.10 375 585 6.9E-63 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 Gene3D G3DSA:3.20.19.10 663 901 5.0E-91 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CSW12_RS09675 e0a281f078e896040f255818504900fb 907 SUPERFAMILY SSF53732 4 636 1.96E-227 T 29-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 29-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CSW12_RS09675 e0a281f078e896040f255818504900fb 907 Gene3D G3DSA:3.30.499.10 33 241 1.1E-69 T 29-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS01010 3b63903c64abdde98ef16260b36932e5 375 Pfam PF08756 YfkB-like domain 221 370 6.0E-75 T 29-03-2018 IPR014866 YfkB-like domain CSW12_RS01010 3b63903c64abdde98ef16260b36932e5 375 SUPERFAMILY SSF102114 34 328 4.05E-26 T 29-03-2018 CSW12_RS01010 3b63903c64abdde98ef16260b36932e5 375 Gene3D G3DSA:3.20.20.70 23 346 6.5E-30 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS01010 3b63903c64abdde98ef16260b36932e5 375 Pfam PF13353 4Fe-4S single cluster domain 41 119 8.9E-7 T 29-03-2018 CSW12_RS01010 3b63903c64abdde98ef16260b36932e5 375 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 370 3.8E-192 T 29-03-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB CSW12_RS01010 3b63903c64abdde98ef16260b36932e5 375 Pfam PF04055 Radical SAM superfamily 37 175 1.6E-10 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Gene3D G3DSA:3.30.70.270 462 632 1.9E-65 T 29-03-2018 CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Pfam PF00563 EAL domain 642 876 1.8E-73 T 29-03-2018 IPR001633 EAL domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 SUPERFAMILY SSF141868 640 888 8.63E-87 T 29-03-2018 IPR001633 EAL domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 SUPERFAMILY SSF55785 334 451 1.66E-14 T 29-03-2018 IPR000014 PAS domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 SMART SM00267 453 625 2.6E-75 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Pfam PF13321 Domain of unknown function (DUF4084) 1 304 2.3E-178 T 29-03-2018 IPR025152 Domain of unknown function DUF4084 CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 338 458 1.4E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Pfam PF00989 PAS fold 342 450 3.0E-9 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Pfam PF00990 Diguanylate cyclase, GGDEF domain 464 621 2.8E-54 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 SMART SM00052 635 881 1.2E-118 T 29-03-2018 IPR001633 EAL domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Gene3D G3DSA:3.20.20.450 633 892 1.5E-96 T 29-03-2018 IPR001633 EAL domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 461 623 5.3E-49 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 SUPERFAMILY SSF55073 469 627 1.26E-54 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS26535 5a714489eeb7a181d65dd02e8d54b773 892 Gene3D G3DSA:3.30.450.20 323 461 4.8E-19 T 29-03-2018 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 Pfam PF13394 4Fe-4S single cluster domain 124 217 7.9E-5 T 29-03-2018 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 16 358 71.209 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 Pfam PF04055 Radical SAM superfamily 119 289 1.7E-17 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 PIRSF PIRSF006004 8 362 1.1E-134 T 29-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 Gene3D G3DSA:3.20.20.70 25 359 1.2E-35 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 13 362 2.3E-159 T 29-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CSW12_RS08450 135ad44ac1a4340184fffb5e7dc0e541 362 SUPERFAMILY SSF102114 102 320 9.42E-14 T 29-03-2018 CSW12_RS20315 6ceb7e4672b6bb1897c3f867624f9041 186 Pfam PF03734 L,D-transpeptidase catalytic domain 28 151 1.4E-23 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CSW12_RS20315 6ceb7e4672b6bb1897c3f867624f9041 186 Gene3D G3DSA:2.40.440.10 21 153 2.6E-34 T 29-03-2018 CSW12_RS20315 6ceb7e4672b6bb1897c3f867624f9041 186 SUPERFAMILY SSF141523 26 151 1.15E-33 T 29-03-2018 CSW12_RS03690 3296f880ba66ce86b1f20a00a0cb4946 252 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 18 249 2.9E-98 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CSW12_RS03690 3296f880ba66ce86b1f20a00a0cb4946 252 Pfam PF03306 Alpha-acetolactate decarboxylase 20 237 3.0E-89 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CSW12_RS03690 3296f880ba66ce86b1f20a00a0cb4946 252 Gene3D G3DSA:3.30.1330.80 108 214 9.6E-45 T 29-03-2018 CSW12_RS03690 3296f880ba66ce86b1f20a00a0cb4946 252 SUPERFAMILY SSF117856 18 249 2.04E-88 T 29-03-2018 CSW12_RS03690 3296f880ba66ce86b1f20a00a0cb4946 252 Gene3D G3DSA:3.30.1330.80 17 107 1.9E-36 T 29-03-2018 CSW12_RS03690 3296f880ba66ce86b1f20a00a0cb4946 252 PIRSF PIRSF001332 5 250 1.4E-105 T 29-03-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 525 2.4E-48 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 188 5.5E-16 T 29-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Gene3D G3DSA:1.10.287.950 181 321 5.1E-7 T 29-03-2018 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Gene3D G3DSA:1.10.287.950 322 511 5.2E-51 T 29-03-2018 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Gene3D G3DSA:1.10.287.1060 512 572 0.17 T 29-03-2018 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Pfam PF00672 HAMP domain 217 264 9.3E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 SMART SM00283 297 572 5.0E-73 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 Gene3D G3DSA:1.20.120.30 25 180 2.1E-8 T 29-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 59 74 4.2E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 395 422 4.2E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 424 453 4.2E-21 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 SMART SM00304 216 268 1.2E-7 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 SUPERFAMILY SSF58104 236 270 3.01E-71 T 29-03-2018 CSW12_RS04885 06d13bde4c237253e44b89ce6be29fc9 575 SUPERFAMILY SSF58104 303 571 3.01E-71 T 29-03-2018 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 Gene3D G3DSA:1.10.357.10 97 217 4.2E-11 T 29-03-2018 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.3E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 Gene3D G3DSA:1.10.260.40 47 96 8.2E-12 T 29-03-2018 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 SUPERFAMILY SSF46689 15 83 3.03E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 4.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 4.9E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 Gene3D G3DSA:1.10.10.60 11 46 2.2E-14 T 29-03-2018 CSW12_RS15050 e6c0611ed896d5d9dfbce946ddd9323e 217 SUPERFAMILY SSF48498 103 215 8.26E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.4E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.4E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.4E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 SMART SM00347 30 129 1.8E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 SUPERFAMILY SSF46785 9 140 1.99E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 Pfam PF12802 MarR family 54 93 5.7E-11 T 29-03-2018 CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 Gene3D G3DSA:1.10.10.10 5 144 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03190 de50e2e6dd2e1a5c86e2b35bc48f279a 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 102 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CSW12_RS10455 413162285311610a29852c207f6f2495 140 Pfam PF06146 Phosphate-starvation-inducible E 60 124 7.6E-17 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like CSW12_RS10455 413162285311610a29852c207f6f2495 140 Hamap MF_01048 Protein PsiE [psiE]. 5 138 26.008 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 CSW12_RS10455 413162285311610a29852c207f6f2495 140 PIRSF PIRSF029598 4 140 3.5E-52 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 684 4.0E-71 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 Gene3D G3DSA:3.90.1310.10 29 320 2.3E-38 T 29-03-2018 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 SUPERFAMILY SSF56519 190 320 5.1E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 SUPERFAMILY SSF56519 57 117 5.1E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 305 1.3E-35 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 Gene3D G3DSA:3.40.710.10 321 702 1.4E-80 T 29-03-2018 CSW12_RS14560 1abd4e28fec9a9662486e759bf8d5b17 708 SUPERFAMILY SSF56601 321 692 5.63E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 SUPERFAMILY SSF81442 51 576 4.84E-175 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 5 645 0.0 T 29-03-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 502 4.7E-142 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 Gene3D G3DSA:1.10.287.70 570 637 7.5E-15 T 29-03-2018 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 277 331 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 345 366 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 458 479 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 275 296 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 336 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 408 427 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 175 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 380 398 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 121 145 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 195 213 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 94 117 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 PRINTS PR01165 Cytochrome c oxidase subunit I signature 224 243 1.5E-98 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02710 b32865437175fe9b9c3e02a634fc0d2f 647 Gene3D G3DSA:1.20.210.10 43 557 9.4E-191 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS12260 512d872ef0445916099d64231e866515 210 Pfam PF02698 DUF218 domain 48 177 3.3E-27 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CSW12_RS12260 512d872ef0445916099d64231e866515 210 Gene3D G3DSA:3.40.50.620 37 178 1.8E-30 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS05765 10a948e2bcc5943621fe8e968a896f20 369 Pfam PF01548 Transposase 7 157 3.8E-15 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS05765 10a948e2bcc5943621fe8e968a896f20 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 1.9E-19 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS25720 5586160ec6d2f038ffd274097026f29f 374 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 88 239 4.3E-51 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS25720 5586160ec6d2f038ffd274097026f29f 374 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 89 239 4.3E-52 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS13100 08e1cc2a3ab033c080a019e200df504b 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 5.1E-23 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13100 08e1cc2a3ab033c080a019e200df504b 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 9.2E-20 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS26935 2eadbdb05ac4d454c810ae669ffe2048 484 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 138 285 2.6E-11 T 29-03-2018 CSW12_RS15365 e71e506c46070d164094f1470776b555 168 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 1.2E-29 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS15365 e71e506c46070d164094f1470776b555 168 SUPERFAMILY SSF55729 2 165 8.07E-47 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS15365 e71e506c46070d164094f1470776b555 168 Gene3D G3DSA:3.40.630.30 1 168 9.4E-32 T 29-03-2018 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 Gene3D G3DSA:1.20.120.640 306 407 5.1E-20 T 29-03-2018 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 1.8E-137 T 29-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 4.3E-189 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.2E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.2E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.2E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.2E-29 T 29-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.297 T 29-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 SUPERFAMILY SSF52374 4 314 1.42E-104 T 29-03-2018 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 SUPERFAMILY SSF47323 317 464 2.03E-34 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 SMART SM00840 353 416 1.3E-14 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 Pfam PF09190 DALR domain 353 413 1.9E-14 T 29-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CSW12_RS27875 ff96f602b87cc48addbff6412a0abc4e 465 Gene3D G3DSA:3.40.50.620 1 305 4.0E-96 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS27055 a452a8883bdb90488401b4d46651c3fa 191 Pfam PF08006 Protein of unknown function (DUF1700) 5 188 5.2E-46 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 CSW12_RS25335 782d141657a2f11e0e73ea1cc2a2dbeb 316 Gene3D G3DSA:3.90.245.10 1 313 5.8E-63 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS25335 782d141657a2f11e0e73ea1cc2a2dbeb 316 SUPERFAMILY SSF53590 1 311 2.35E-74 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS25335 782d141657a2f11e0e73ea1cc2a2dbeb 316 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 305 8.7E-58 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS03870 f3acba4a1f1c19024705ad28991b1d1b 174 Pfam PF07366 SnoaL-like polyketide cyclase 58 165 1.0E-23 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CSW12_RS03870 f3acba4a1f1c19024705ad28991b1d1b 174 Gene3D G3DSA:3.10.450.50 47 174 4.6E-29 T 29-03-2018 CSW12_RS03870 f3acba4a1f1c19024705ad28991b1d1b 174 SUPERFAMILY SSF54427 53 164 1.03E-29 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS18365 89b83e2cacb77225e3e86d5049e6217e 393 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 4 392 2.3E-139 T 29-03-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 CSW12_RS18365 89b83e2cacb77225e3e86d5049e6217e 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 1.1E-62 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS18365 89b83e2cacb77225e3e86d5049e6217e 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 1.2E-23 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 168 2.3E-57 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 181 35.777 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 Gene3D G3DSA:1.10.10.10 1 84 1.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 SUPERFAMILY SSF46785 1 81 5.58E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 PIRSF PIRSF019345 1 184 1.7E-56 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 Gene3D G3DSA:1.10.10.10 85 176 1.7E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 184 6.1E-53 T 29-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CSW12_RS07400 86520390a8f53f71eb4f024b5c0bd4bf 190 SUPERFAMILY SSF46785 86 159 7.48E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26255 10a170e92a8720ce989066d747ba9caf 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 15 332 25.055 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26255 10a170e92a8720ce989066d747ba9caf 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 29-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26255 10a170e92a8720ce989066d747ba9caf 333 Pfam PF00146 NADH dehydrogenase 23 326 2.0E-124 T 29-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 SUPERFAMILY SSF55486 7 499 1.04E-123 T 29-03-2018 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 Gene3D G3DSA:1.10.1370.10 56 504 3.7E-44 T 29-03-2018 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 337 356 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 406 427 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 451 469 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 152 172 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 383 400 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 3.8E-81 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 2 499 1.9E-216 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS19770 abc873ec124d2d5b616cb3ece519ddbc 505 PIRSF PIRSF006615 4 505 1.9E-200 T 29-03-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 SUPERFAMILY SSF81338 2 219 2.88E-57 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 ProSitePatterns PS00221 MIP family signature. 59 67 - T 29-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 Pfam PF00230 Major intrinsic protein 2 212 1.4E-46 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 PRINTS PR00783 Major intrinsic protein family signature 3 22 8.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 PRINTS PR00783 Major intrinsic protein family signature 78 97 8.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 PRINTS PR00783 Major intrinsic protein family signature 41 65 8.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 PRINTS PR00783 Major intrinsic protein family signature 196 216 8.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 PRINTS PR00783 Major intrinsic protein family signature 127 145 8.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 PRINTS PR00783 Major intrinsic protein family signature 157 179 8.9E-52 T 29-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CSW12_RS22125 f41a671ed27679cbde1407eba7414659 221 Gene3D G3DSA:1.20.1080.10 1 221 2.1E-59 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS20885 ed3bf7f30e7d250bc8a37e24cc3745e0 610 Pfam PF02574 Homocysteine S-methyltransferase 12 281 2.7E-50 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS20885 ed3bf7f30e7d250bc8a37e24cc3745e0 610 SUPERFAMILY SSF82282 3 360 3.14E-93 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS20885 ed3bf7f30e7d250bc8a37e24cc3745e0 610 Gene3D G3DSA:3.20.20.220 291 609 5.7E-66 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CSW12_RS20885 ed3bf7f30e7d250bc8a37e24cc3745e0 610 SUPERFAMILY SSF51730 316 600 3.53E-71 T 29-03-2018 IPR029041 FAD-linked oxidoreductase-like CSW12_RS20885 ed3bf7f30e7d250bc8a37e24cc3745e0 610 Gene3D G3DSA:3.20.20.330 1 290 2.0E-73 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS20885 ed3bf7f30e7d250bc8a37e24cc3745e0 610 Pfam PF02219 Methylenetetrahydrofolate reductase 316 575 8.5E-31 T 29-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 SUPERFAMILY SSF52172 3 129 3.7E-44 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 4.9E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 SMART SM00448 3 113 1.9E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 Gene3D G3DSA:3.40.50.2300 2 125 4.4E-39 T 29-03-2018 CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 Gene3D G3DSA:1.10.10.10 126 228 3.9E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 SUPERFAMILY SSF46894 128 228 1.67E-29 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 Pfam PF00072 Response regulator receiver domain 5 114 3.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11740 a2fa07aee64cbe752a5d3293ea9a6e74 228 SMART SM00862 152 228 1.7E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS15350 7b6c67616a8bbaeab78d24fc7e785def 472 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 249 360 3.2E-17 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CSW12_RS15350 7b6c67616a8bbaeab78d24fc7e785def 472 Gene3D G3DSA:1.10.530.10 233 362 3.8E-26 T 29-03-2018 CSW12_RS15350 7b6c67616a8bbaeab78d24fc7e785def 472 Pfam PF00395 S-layer homology domain 87 129 2.7E-12 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS15350 7b6c67616a8bbaeab78d24fc7e785def 472 Pfam PF00395 S-layer homology domain 33 68 2.8E-6 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS15350 7b6c67616a8bbaeab78d24fc7e785def 472 Pfam PF00395 S-layer homology domain 149 190 2.4E-8 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS15350 7b6c67616a8bbaeab78d24fc7e785def 472 SMART SM00047 240 363 5.7E-6 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CSW12_RS11085 df755373776d77f72dca90075818049e 351 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 6 348 1.7E-149 T 29-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 CSW12_RS11085 df755373776d77f72dca90075818049e 351 SUPERFAMILY SSF51735 9 331 2.65E-67 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11085 df755373776d77f72dca90075818049e 351 Pfam PF16363 GDP-mannose 4,6 dehydratase 13 319 4.7E-38 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11085 df755373776d77f72dca90075818049e 351 Gene3D G3DSA:3.40.50.720 1 196 1.0E-31 T 29-03-2018 CSW12_RS11085 df755373776d77f72dca90075818049e 351 Gene3D G3DSA:3.90.25.10 197 351 4.2E-29 T 29-03-2018 CSW12_RS10775 953373e4d52137959881307fffa9a9f5 494 Gene3D G3DSA:2.120.10.10 159 493 2.3E-16 T 29-03-2018 CSW12_RS10775 953373e4d52137959881307fffa9a9f5 494 SUPERFAMILY SSF110296 100 161 7.32E-21 T 29-03-2018 CSW12_RS10775 953373e4d52137959881307fffa9a9f5 494 SUPERFAMILY SSF110296 254 488 7.32E-21 T 29-03-2018 CSW12_RS06495 d866bb6ba4926ac66f4773950986fb13 195 Gene3D G3DSA:3.40.30.10 11 192 1.2E-12 T 29-03-2018 CSW12_RS06495 d866bb6ba4926ac66f4773950986fb13 195 SUPERFAMILY SSF52833 58 148 1.67E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS06495 d866bb6ba4926ac66f4773950986fb13 195 Pfam PF14595 Thioredoxin 21 149 1.2E-39 T 29-03-2018 CSW12_RS08950 4e0299bfaf1b4edec04eb2647ffab9e0 927 SUPERFAMILY SSF48452 46 168 1.42E-12 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS08950 4e0299bfaf1b4edec04eb2647ffab9e0 927 Pfam PF00350 Dynamin family 380 516 2.1E-10 T 29-03-2018 IPR022812 Dynamin superfamily CSW12_RS08950 4e0299bfaf1b4edec04eb2647ffab9e0 927 Gene3D G3DSA:3.40.50.300 375 754 4.0E-22 T 29-03-2018 CSW12_RS08950 4e0299bfaf1b4edec04eb2647ffab9e0 927 SUPERFAMILY SSF52540 369 610 1.91E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08950 4e0299bfaf1b4edec04eb2647ffab9e0 927 Gene3D G3DSA:1.25.40.10 24 168 5.7E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS09025 5c2a6e1b76618b5de138c2fc121e9379 392 Pfam PF10720 Protein of unknown function (DUF2515) 51 381 5.5E-128 T 29-03-2018 IPR019658 Protein of unknown function DUF2515 CSW12_RS15850 d41dfcbc0f784b6930adc394c879d8e3 94 Pfam PF13799 Domain of unknown function (DUF4183) 21 91 3.9E-19 T 29-03-2018 IPR025237 Domain of unknown function DUF4183 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 Gene3D G3DSA:3.40.50.1370 153 310 1.3E-40 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 Gene3D G3DSA:3.40.50.1370 1 152 2.2E-58 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 9.9E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 9.9E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 9.9E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 9.9E-23 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 SUPERFAMILY SSF53671 1 301 2.23E-90 T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 2.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 257 262 2.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 2.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 2.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 281 295 2.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 2.5E-32 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 302 40.347 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 29-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 139 1.4E-41 T 29-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 296 1.4E-20 T 29-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CSW12_RS08310 18c66284fadf8cadf63c6851d3946d83 313 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 298 4.2E-97 T 29-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS19210 b8462ce7bf6bc80eaf4ef80f0596ec84 257 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 250 4.2E-11 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CSW12_RS19210 b8462ce7bf6bc80eaf4ef80f0596ec84 257 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 134 1.1E-23 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CSW12_RS19210 b8462ce7bf6bc80eaf4ef80f0596ec84 257 Pfam PF00460 Flagella basal body rod protein 4 34 8.1E-7 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CSW12_RS19210 b8462ce7bf6bc80eaf4ef80f0596ec84 257 SUPERFAMILY SSF117143 101 190 1.05E-12 T 29-03-2018 CSW12_RS05675 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 Pfam PF13563 2'-5' RNA ligase superfamily 13 153 1.6E-24 T 29-03-2018 CSW12_RS05675 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 Gene3D G3DSA:3.90.1140.10 1 171 3.9E-30 T 29-03-2018 CSW12_RS05675 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 SUPERFAMILY SSF55144 1 170 2.62E-33 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CSW12_RS05675 2a9d7c4ffcb6c1b6c0ff24923d2b836b 172 Hamap MF_01444 Putative phosphoesterase . 1 168 39.296 T 29-03-2018 IPR022932 Putative phosphoesterase YjcG CSW12_RS12225 8bf93f24014fc57919d04dfbc876252e 168 SUPERFAMILY SSF55729 7 150 6.76E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12225 8bf93f24014fc57919d04dfbc876252e 168 Gene3D G3DSA:3.40.630.30 6 167 1.4E-16 T 29-03-2018 CSW12_RS12225 8bf93f24014fc57919d04dfbc876252e 168 Pfam PF13302 Acetyltransferase (GNAT) domain 46 148 1.5E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS16640 ed6635d55e4bd0b0a43ff2f25537da36 287 Gene3D G3DSA:3.10.310.10 131 272 1.0E-31 T 29-03-2018 CSW12_RS16640 ed6635d55e4bd0b0a43ff2f25537da36 287 PIRSF PIRSF016184 1 283 3.3E-80 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CSW12_RS16640 ed6635d55e4bd0b0a43ff2f25537da36 287 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 283 8.4E-54 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CSW12_RS16640 ed6635d55e4bd0b0a43ff2f25537da36 287 Pfam PF02567 Phenazine biosynthesis-like protein 9 275 1.7E-53 T 29-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CSW12_RS16640 ed6635d55e4bd0b0a43ff2f25537da36 287 SUPERFAMILY SSF54506 1 279 9.62E-69 T 29-03-2018 CSW12_RS16640 ed6635d55e4bd0b0a43ff2f25537da36 287 Gene3D G3DSA:3.10.310.10 1 130 3.2E-26 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 SUPERFAMILY SSF58104 365 608 9.68E-9 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 SUPERFAMILY SSF101967 175 299 4.18E-6 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 Pfam PF12698 ABC-2 family transporter protein 24 169 3.0E-15 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 Pfam PF12698 ABC-2 family transporter protein 716 898 5.1E-13 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 Gene3D G3DSA:1.20.120.570 276 419 2.2E-24 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 Gene3D G3DSA:1.20.120.570 420 567 3.0E-11 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 Gene3D G3DSA:1.20.120.570 568 707 9.0E-21 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 Gene3D G3DSA:3.40.1710.10 46 206 5.3E-27 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 SUPERFAMILY SSF101967 547 678 1.96E-13 T 29-03-2018 CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 231 258 1.8E-6 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 259 286 3.1E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 638 665 3.1E-8 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 203 230 1.0E-6 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 610 637 6.4E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 315 342 4.6E-5 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 287 314 4.6E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 554 581 6.1E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 582 609 3.0E-7 T 29-03-2018 IPR023908 xxxLxxG heptad repeat CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 172 1.1E-61 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CSW12_RS04720 b49fb7c1a5715750411c513ea3c82074 923 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 705 907 1.9E-66 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CSW12_RS23240 85ab03cbe9a3577a5ebeeb8256bf9b95 143 SUPERFAMILY SSF55961 3 143 1.18E-42 T 29-03-2018 CSW12_RS23240 85ab03cbe9a3577a5ebeeb8256bf9b95 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 142 7.2E-12 T 29-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CSW12_RS23240 85ab03cbe9a3577a5ebeeb8256bf9b95 143 Gene3D G3DSA:3.30.530.20 1 143 3.0E-24 T 29-03-2018 IPR023393 START-like domain CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 Gene3D G3DSA:1.10.275.10 1 195 4.4E-73 T 29-03-2018 IPR024083 Fumarase/histidase, N-terminal CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 Pfam PF00221 Aromatic amino acid lyase 9 466 8.3E-195 T 29-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 SUPERFAMILY SSF48557 1 493 6.04E-194 T 29-03-2018 IPR008948 L-Aspartase-like GO:0003824 CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 44.739 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 493 6.9E-215 T 29-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 Gene3D G3DSA:1.20.200.10 197 503 3.6E-125 T 29-03-2018 CSW12_RS09490 00d32e97b37c7f801a966a28d2d28eec 505 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 29-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 SMART SM00421 9 66 4.9E-25 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 2.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 2.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 2.6E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 ProSitePatterns PS00622 LuxR-type HTH domain signature. 26 53 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 64 6.3E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 SUPERFAMILY SSF46894 7 72 4.76E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS22095 cb8957cb8654812e171c05b44751e641 74 Gene3D G3DSA:1.10.10.10 11 72 2.7E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13010 ee4a492b2dafdbdce340599ed26bb276 43 Gene3D G3DSA:1.20.120.450 2 39 2.8E-6 T 29-03-2018 CSW12_RS13010 ee4a492b2dafdbdce340599ed26bb276 43 SUPERFAMILY SSF109854 5 34 4.88E-7 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 1.1E-39 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 SMART SM00861 4 179 6.6E-65 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 5.0E-40 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 Gene3D G3DSA:3.40.50.920 195 324 1.2E-37 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 SUPERFAMILY SSF52922 188 325 4.32E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 Gene3D G3DSA:3.40.50.970 1 194 8.5E-63 T 29-03-2018 CSW12_RS07885 985e5084bd96e5d8db7791cce93851d1 325 SUPERFAMILY SSF52518 3 192 2.65E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 Gene3D G3DSA:3.40.1710.10 48 199 1.6E-28 T 29-03-2018 CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 11 173 4.7E-49 T 29-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 770 971 1.8E-49 T 29-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 Pfam PF01061 ABC-2 type transporter 823 939 7.8E-9 T 29-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 Gene3D G3DSA:1.10.287.500 200 481 0.19 T 29-03-2018 CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 Gene3D G3DSA:1.20.1170.10 585 828 3.3E-15 T 29-03-2018 CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 Gene3D G3DSA:1.20.5.110 487 562 0.0057 T 29-03-2018 CSW12_RS00755 b4cb94e120c92f6eb4b153b6d14a42b2 991 Pfam PF12698 ABC-2 family transporter protein 24 160 1.8E-8 T 29-03-2018 CSW12_RS06355 3902cca654bc9a92ba408227b7342a69 337 Pfam PF02517 CAAX protease self-immunity 130 213 4.7E-21 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS06355 3902cca654bc9a92ba408227b7342a69 337 SUPERFAMILY SSF89447 294 335 6.63E-5 T 29-03-2018 CSW12_RS06355 3902cca654bc9a92ba408227b7342a69 337 Gene3D G3DSA:2.10.260.10 299 333 2.1E-5 T 29-03-2018 CSW12_RS24795 3ee6e4aff204b15c09fa3aaa7300617b 83 Gene3D G3DSA:1.20.1260.10 1 60 2.0E-5 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS24795 3ee6e4aff204b15c09fa3aaa7300617b 83 Pfam PF07875 Coat F domain 2 63 2.3E-18 T 29-03-2018 IPR012851 Spore coat protein CotF-like CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 SUPERFAMILY SSF143856 101 217 7.06E-53 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 Gene3D G3DSA:3.40.720.10 204 394 2.9E-13 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 PIRSF PIRSF001491 3 393 4.7E-170 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 Pfam PF01676 Metalloenzyme superfamily 5 380 3.7E-43 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 SUPERFAMILY SSF53649 218 392 1.31E-79 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 SUPERFAMILY SSF53649 3 101 1.31E-79 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 Gene3D G3DSA:3.30.70.1250 100 203 8.0E-59 T 29-03-2018 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 Hamap MF_00740 Phosphopentomutase [deoB]. 4 389 57.435 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CSW12_RS07235 89ce4f992aa99d0a2a407021cef95603 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 387 7.8E-207 T 29-03-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 CSW12_RS18345 cec21668577b5d1c916e32d77c96fd8f 76 Hamap MF_01103 UPF0291 protein . 1 58 13.72 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CSW12_RS18345 cec21668577b5d1c916e32d77c96fd8f 76 Gene3D G3DSA:1.10.287.540 2 54 5.2E-21 T 29-03-2018 CSW12_RS18345 cec21668577b5d1c916e32d77c96fd8f 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 64 5.1E-24 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CSW12_RS18345 cec21668577b5d1c916e32d77c96fd8f 76 SUPERFAMILY SSF158221 1 40 3.66E-12 T 29-03-2018 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 SMART SM00304 182 234 5.2E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 Gene3D G3DSA:3.30.565.10 297 452 2.6E-42 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 452 1.7E-24 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 Gene3D G3DSA:3.30.450.20 26 156 2.0E-7 T 29-03-2018 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 SUPERFAMILY SSF55874 292 452 7.47E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 Gene3D G3DSA:1.10.287.130 225 296 3.7E-19 T 29-03-2018 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 SMART SM00388 235 302 2.1E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 SMART SM00387 346 452 3.7E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 5.7E-15 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 SUPERFAMILY SSF47384 218 303 2.16E-21 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 301 5.2E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS17980 87f10448c7292b9572448a1245e8b98b 452 SUPERFAMILY SSF158472 184 229 7.72E-7 T 29-03-2018 CSW12_RS26865 61abe39625ff44ce231bfd7931beba71 691 Pfam PF02554 Carbon starvation protein CstA 32 409 1.7E-172 T 29-03-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CSW12_RS26865 61abe39625ff44ce231bfd7931beba71 691 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 7.0E-36 T 29-03-2018 IPR025299 CstA, C-terminal domain CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 Pfam PF00072 Response regulator receiver domain 5 113 2.5E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 Gene3D G3DSA:3.40.50.2300 1 125 1.1E-35 T 29-03-2018 CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 SUPERFAMILY SSF52172 2 128 5.12E-40 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 SMART SM00862 151 227 2.9E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 3.3E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 Gene3D G3DSA:1.10.10.10 126 230 4.6E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 SUPERFAMILY SSF46894 130 228 3.4E-32 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS22295 12adedad2ce65e293fe63cccb9c3af65 230 SMART SM00448 3 113 3.2E-43 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 228 243 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PRINTS PR00069 Aldo-keto reductase signature 195 219 4.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PRINTS PR00069 Aldo-keto reductase signature 123 140 4.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PRINTS PR00069 Aldo-keto reductase signature 157 186 4.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 Pfam PF00248 Aldo/keto reductase family 24 260 5.0E-49 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PIRSF PIRSF000097 2 117 1.1E-44 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 PIRSF PIRSF000097 113 273 4.4E-54 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 Gene3D G3DSA:3.20.20.100 1 274 2.4E-101 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 SUPERFAMILY SSF51430 5 266 4.98E-96 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS07185 04afe6a37ded1decd82f8b6cfe24feec 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS06645 7637d1656982e6f5f0e27dca49a65c62 338 SUPERFAMILY SSF89550 63 84 1.24E-34 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CSW12_RS06645 7637d1656982e6f5f0e27dca49a65c62 338 SUPERFAMILY SSF89550 118 330 1.24E-34 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CSW12_RS06645 7637d1656982e6f5f0e27dca49a65c62 338 Gene3D G3DSA:3.20.20.140 1 316 5.6E-40 T 29-03-2018 CSW12_RS06645 7637d1656982e6f5f0e27dca49a65c62 338 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 60 301 3.5E-28 T 29-03-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 PIRSF PIRSF002191 1 114 3.3E-51 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 29-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 2.5E-51 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 SUPERFAMILY SSF50104 2 113 1.1E-48 T 29-03-2018 IPR008991 Translation protein SH3-like domain CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 Pfam PF01245 Ribosomal protein L19 4 112 3.0E-53 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08575 2c011d0aa596b824045bf8e2be261b34 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 114 32.208 T 29-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 1.2E-129 T 29-03-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 2.0E-113 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 PIRSF PIRSF001359 1 285 2.5E-125 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 Gene3D G3DSA:3.20.20.70 1 285 5.6E-107 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 SUPERFAMILY SSF51569 1 285 2.78E-105 T 29-03-2018 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 1.5E-105 T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CSW12_RS26470 fa54b268b152e0322cdb4db51ea3c5ab 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 29-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 2.2E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 Gene3D G3DSA:3.40.50.2300 1 122 1.3E-43 T 29-03-2018 CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 SUPERFAMILY SSF52172 1 180 1.18E-46 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 Pfam PF00072 Response regulator receiver domain 6 114 1.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 SMART SM00862 148 221 2.5E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 Gene3D G3DSA:1.10.10.10 123 223 6.2E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06040 733cba794ee985bfeb64ce1cddb63a9c 223 SMART SM00448 4 114 1.5E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS27665 3ded9fcfa0da695c2391734e562b599c 808 SMART SM00332 587 788 6.5E-4 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS27665 3ded9fcfa0da695c2391734e562b599c 808 SUPERFAMILY SSF81606 579 791 2.35E-21 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS27665 3ded9fcfa0da695c2391734e562b599c 808 Gene3D G3DSA:3.60.40.10 571 799 1.3E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS27665 3ded9fcfa0da695c2391734e562b599c 808 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 28 790 2.8E-255 T 29-03-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS27665 3ded9fcfa0da695c2391734e562b599c 808 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 605 790 4.1E-36 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS27665 3ded9fcfa0da695c2391734e562b599c 808 SMART SM00331 578 790 4.7E-51 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS09300 b97ed95957dfc40fdd36d416bbeee28a 218 Pfam PF00239 Resolvase, N terminal domain 3 147 2.1E-26 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS09300 b97ed95957dfc40fdd36d416bbeee28a 218 Gene3D G3DSA:3.40.50.1390 1 149 6.2E-30 T 29-03-2018 CSW12_RS09300 b97ed95957dfc40fdd36d416bbeee28a 218 SUPERFAMILY SSF53041 1 149 1.7E-25 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS09300 b97ed95957dfc40fdd36d416bbeee28a 218 Gene3D G3DSA:1.10.10.60 150 217 3.6E-4 T 29-03-2018 CSW12_RS09300 b97ed95957dfc40fdd36d416bbeee28a 218 SMART SM00857 3 149 2.3E-34 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30180 1d81d4be454c29744645567134fbf9ca 290 SUPERFAMILY SSF88713 75 254 9.73E-30 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS30180 1d81d4be454c29744645567134fbf9ca 290 Pfam PF01522 Polysaccharide deacetylase 111 244 1.4E-22 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS30180 1d81d4be454c29744645567134fbf9ca 290 Gene3D G3DSA:3.20.20.370 62 287 1.3E-33 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Gene3D G3DSA:3.30.70.1430 582 671 2.2E-6 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Pfam PF00873 AcrB/AcrD/AcrF family 4 244 2.9E-43 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Pfam PF00873 AcrB/AcrD/AcrF family 278 1029 1.1E-171 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Gene3D G3DSA:1.20.1640.10 292 518 4.6E-46 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Gene3D G3DSA:1.20.1640.10 812 1031 1.2E-39 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 SUPERFAMILY SSF82693 134 180 5.58E-17 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 SUPERFAMILY SSF82693 292 345 5.58E-17 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 489 512 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 353 376 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 380 401 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 566 583 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 408 432 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.5E-48 T 29-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 SUPERFAMILY SSF82693 41 133 2.09E-21 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 SUPERFAMILY SSF82714 726 810 6.54E-9 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Gene3D G3DSA:3.30.2090.10 179 291 5.1E-10 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Gene3D G3DSA:3.30.70.1430 41 140 1.2E-23 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 SUPERFAMILY SSF82866 314 515 1.57E-43 T 29-03-2018 CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 Gene3D G3DSA:3.30.2090.10 724 811 2.3E-12 T 29-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CSW12_RS26955 e0516eb3c1f870150d83220f457cf008 1038 SUPERFAMILY SSF82866 811 1035 4.32E-47 T 29-03-2018 CSW12_RS08150 83eed7071af34c22f254ff52f89df4a4 157 PIRSF PIRSF037732 1 157 1.5E-78 T 29-03-2018 IPR017274 Putative N-acetyltransferase YlbP CSW12_RS08150 83eed7071af34c22f254ff52f89df4a4 157 SUPERFAMILY SSF55729 33 145 1.43E-11 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS08150 83eed7071af34c22f254ff52f89df4a4 157 Hamap MF_00824 Uncharacterized N-acetyltransferase . 3 144 38.063 T 29-03-2018 IPR017274 Putative N-acetyltransferase YlbP CSW12_RS08150 83eed7071af34c22f254ff52f89df4a4 157 Pfam PF00583 Acetyltransferase (GNAT) family 35 107 1.3E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS08150 83eed7071af34c22f254ff52f89df4a4 157 Gene3D G3DSA:3.40.630.30 2 155 1.0E-17 T 29-03-2018 CSW12_RS02480 4d7adbfa5af008a4fed407e72304bc4d 150 Gene3D G3DSA:2.60.40.1080 58 144 5.2E-20 T 29-03-2018 CSW12_RS02480 4d7adbfa5af008a4fed407e72304bc4d 150 Pfam PF02368 Bacterial Ig-like domain (group 2) 61 138 2.3E-10 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CSW12_RS02480 4d7adbfa5af008a4fed407e72304bc4d 150 SMART SM00635 61 138 5.6E-8 T 29-03-2018 IPR003343 Bacterial Ig-like, group 2 CSW12_RS02480 4d7adbfa5af008a4fed407e72304bc4d 150 Gene3D G3DSA:2.60.40.10 2 57 1.6E-12 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS02480 4d7adbfa5af008a4fed407e72304bc4d 150 SUPERFAMILY SSF49265 3 62 9.08E-12 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS02480 4d7adbfa5af008a4fed407e72304bc4d 150 SUPERFAMILY SSF49373 60 141 9.42E-15 T 29-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CSW12_RS07380 48e916a6f7e9f510a41624d46b4cde9c 172 Pfam PF03745 Domain of unknown function (DUF309) 7 66 7.9E-21 T 29-03-2018 IPR005500 Protein of unknown function DUF309 CSW12_RS07380 48e916a6f7e9f510a41624d46b4cde9c 172 Gene3D G3DSA:1.10.3450.10 1 135 1.4E-35 T 29-03-2018 IPR023203 TTHA0068-like domain CSW12_RS07380 48e916a6f7e9f510a41624d46b4cde9c 172 SUPERFAMILY SSF140663 1 129 1.23E-32 T 29-03-2018 IPR023203 TTHA0068-like domain CSW12_RS07200 ba35633d785c939d5b92fd62354fe502 179 SUPERFAMILY SSF55811 8 178 2.44E-51 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS07200 ba35633d785c939d5b92fd62354fe502 179 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS07200 ba35633d785c939d5b92fd62354fe502 179 Pfam PF00293 NUDIX domain 43 164 4.9E-22 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS07200 ba35633d785c939d5b92fd62354fe502 179 Gene3D G3DSA:3.90.79.10 4 179 7.4E-43 T 29-03-2018 CSW12_RS07200 ba35633d785c939d5b92fd62354fe502 179 PRINTS PR00502 NUDIX hydrolase family signature 72 86 3.5E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS07200 ba35633d785c939d5b92fd62354fe502 179 PRINTS PR00502 NUDIX hydrolase family signature 86 101 3.5E-5 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS23360 2d2fa11b7779c5863e87569e20112708 364 Pfam PF03845 Spore germination protein 9 326 1.1E-102 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS23360 2d2fa11b7779c5863e87569e20112708 364 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 360 8.9E-49 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS12170 388a0b317459ccbdbf20d372f964721a 385 Gene3D G3DSA:3.40.710.10 43 381 1.5E-72 T 29-03-2018 CSW12_RS12170 388a0b317459ccbdbf20d372f964721a 385 Pfam PF00144 Beta-lactamase 62 382 1.6E-64 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS12170 388a0b317459ccbdbf20d372f964721a 385 SUPERFAMILY SSF56601 53 372 1.14E-76 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 SMART SM00490 563 660 8.9E-8 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 Pfam PF04851 Type III restriction enzyme, res subunit 264 428 2.0E-16 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 SUPERFAMILY SSF52540 187 445 3.17E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 SMART SM00487 261 460 1.5E-24 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 SUPERFAMILY SSF52540 529 705 9.31E-35 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 Gene3D G3DSA:3.40.50.300 262 430 2.7E-28 T 29-03-2018 CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 TIGRFAM TIGR00595 priA: primosomal protein N' 289 797 2.4E-219 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 Gene3D G3DSA:3.40.50.300 461 686 7.0E-19 T 29-03-2018 CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 800 25.011 T 29-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CSW12_RS08430 83e0aa673add791a409dddcc9fa76220 801 Pfam PF00271 Helicase conserved C-terminal domain 563 659 1.6E-7 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS22350 2050026dd4ab9d0330242d7c5e96a6bd 237 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 206 234 7.5E-15 T 29-03-2018 IPR017502 Sortase B cell surface sorting signal CSW12_RS22350 2050026dd4ab9d0330242d7c5e96a6bd 237 Pfam PF05031 Iron Transport-associated domain 31 146 1.2E-39 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22350 2050026dd4ab9d0330242d7c5e96a6bd 237 SMART SM00725 32 153 9.4E-47 T 29-03-2018 IPR006635 NEAT domain CSW12_RS22350 2050026dd4ab9d0330242d7c5e96a6bd 237 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 1 236 1.2E-98 T 29-03-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 CSW12_RS22350 2050026dd4ab9d0330242d7c5e96a6bd 237 SUPERFAMILY SSF158911 24 155 2.62E-43 T 29-03-2018 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 SUPERFAMILY SSF88659 114 190 1.92E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 Gene3D G3DSA:1.10.601.10 4 110 4.0E-33 T 29-03-2018 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PIRSF PIRSF000770 118 157 0.4 T 29-03-2018 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PIRSF PIRSF000770 159 259 5.9E-15 T 29-03-2018 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PIRSF PIRSF000770 13 131 1.8E-18 T 29-03-2018 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.5E-84 T 29-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 SUPERFAMILY SSF88659 175 258 8.04E-17 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 Gene3D G3DSA:1.10.1270.10 179 259 4.9E-16 T 29-03-2018 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 Pfam PF04542 Sigma-70 region 2 42 110 2.4E-17 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 255 8.9E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 Pfam PF04545 Sigma-70, region 4 207 253 1.7E-13 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 1.1E-157 T 29-03-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 1.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 1.6E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 SUPERFAMILY SSF88946 6 110 2.49E-33 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08240 d32a842733e4149f418e19c7d3361d4e 259 Gene3D G3DSA:1.10.10.10 111 163 3.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS05555 c5ecb45ca42268f0ad4d02c2662f0b45 462 Gene3D G3DSA:2.40.300.10 308 378 1.2E-16 T 29-03-2018 CSW12_RS05555 c5ecb45ca42268f0ad4d02c2662f0b45 462 Gene3D G3DSA:2.40.300.10 379 457 3.7E-19 T 29-03-2018 CSW12_RS05555 c5ecb45ca42268f0ad4d02c2662f0b45 462 Gene3D G3DSA:2.150.10.10 140 307 1.0E-9 T 29-03-2018 CSW12_RS05555 c5ecb45ca42268f0ad4d02c2662f0b45 462 Pfam PF11962 Peptidase_G2, IMC autoproteolytic cleavage domain 264 452 1.0E-43 T 29-03-2018 IPR021865 Peptidase G2, IMC autoproteolytic cleavage domain CSW12_RS05555 c5ecb45ca42268f0ad4d02c2662f0b45 462 SUPERFAMILY SSF101967 148 280 1.06E-12 T 29-03-2018 CSW12_RS24810 7d5efd67323b8a666080b128b4372d0c 182 Gene3D G3DSA:1.10.10.60 1 50 5.1E-10 T 29-03-2018 CSW12_RS24810 7d5efd67323b8a666080b128b4372d0c 182 Pfam PF13305 WHG domain 85 157 1.7E-12 T 29-03-2018 IPR025996 WHG domain CSW12_RS24810 7d5efd67323b8a666080b128b4372d0c 182 SUPERFAMILY SSF48498 79 180 2.74E-25 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS24810 7d5efd67323b8a666080b128b4372d0c 182 SUPERFAMILY SSF46689 6 74 6.67E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS24810 7d5efd67323b8a666080b128b4372d0c 182 Gene3D G3DSA:1.10.357.10 51 182 1.2E-18 T 29-03-2018 CSW12_RS15055 3f1758ba1e3c757b58e684fcfc86d38b 339 Pfam PF12698 ABC-2 family transporter protein 18 327 3.2E-35 T 29-03-2018 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 SUPERFAMILY SSF48168 5 158 4.58E-39 T 29-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 SUPERFAMILY SSF51998 159 683 4.27E-173 T 29-03-2018 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 552 574 - T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 Gene3D G3DSA:3.20.70.20 62 686 4.2E-159 T 29-03-2018 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 Pfam PF08343 Ribonucleotide reductase N-terminal 3 81 2.9E-20 T 29-03-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 3 694 0.0 T 29-03-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 Pfam PF02867 Ribonucleotide reductase, barrel domain 160 678 4.1E-140 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 481 504 3.4E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 370 381 3.4E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 235 254 3.4E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 414 437 3.4E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 563 590 3.4E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 PRINTS PR01183 Ribonucleotide reductase large chain signature 453 475 3.4E-30 T 29-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 86 682 1.1E-170 T 29-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS06310 848d535ab9513a8410c1188bd2cf09ea 694 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 84 155 2.1E-13 T 29-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS10600 89884f79470b3e3bbdf2fd820224c1b1 220 SUPERFAMILY SSF102588 3 218 1.1E-48 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CSW12_RS10600 89884f79470b3e3bbdf2fd820224c1b1 220 Gene3D G3DSA:3.40.50.10320 1 215 8.9E-47 T 29-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CSW12_RS10600 89884f79470b3e3bbdf2fd820224c1b1 220 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 3.1E-29 T 29-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CSW12_RS10600 89884f79470b3e3bbdf2fd820224c1b1 220 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 219 1.1E-100 T 29-03-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 Pfam PF01022 Bacterial regulatory protein, arsR family 23 69 4.8E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 1.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 1.3E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 Gene3D G3DSA:1.10.10.10 20 83 3.9E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 SMART SM00418 16 92 9.9E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS15285 a4c3428ce23f0ae0a65987b535550dab 103 SUPERFAMILY SSF46785 11 95 9.09E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27040 996322509d2cd913ab402f209ded75a8 59 Pfam PF13333 Integrase core domain 2 57 3.2E-14 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CSW12_RS27040 996322509d2cd913ab402f209ded75a8 59 Gene3D G3DSA:3.30.420.10 1 59 1.3E-6 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS27040 996322509d2cd913ab402f209ded75a8 59 SUPERFAMILY SSF53098 1 55 1.5E-5 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS12690 2302a7d331bccb0804af22a0b6512f58 795 Pfam PF05547 Immune inhibitor A peptidase M6 148 791 8.3E-299 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS12690 2302a7d331bccb0804af22a0b6512f58 795 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 183 492 4.7E-88 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS12690 2302a7d331bccb0804af22a0b6512f58 795 SUPERFAMILY SSF55486 354 429 8.1E-17 T 29-03-2018 CSW12_RS12690 2302a7d331bccb0804af22a0b6512f58 795 SUPERFAMILY SSF55486 262 304 8.1E-17 T 29-03-2018 CSW12_RS12690 2302a7d331bccb0804af22a0b6512f58 795 Gene3D G3DSA:2.60.120.260 386 608 2.8E-13 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS12690 2302a7d331bccb0804af22a0b6512f58 795 PIRSF PIRSF007519 1 795 0.0 T 29-03-2018 IPR012300 Peptidase M6, InhA CSW12_RS10080 290bf4223a2bb8429e8696126e42b191 363 Pfam PF13037 Domain of unknown function (DUF3898) 261 350 5.1E-43 T 29-03-2018 IPR025012 Domain of unknown function DUF3898 CSW12_RS10080 290bf4223a2bb8429e8696126e42b191 363 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 2.9E-136 T 29-03-2018 IPR025006 Protein of unknown function DUF3900 CSW12_RS12325 ecf18456548b8eb09fe4b94cc4cb273a 245 Gene3D G3DSA:3.40.50.1220 4 243 1.6E-57 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS12325 ecf18456548b8eb09fe4b94cc4cb273a 245 Pfam PF02146 Sir2 family 25 196 2.1E-51 T 29-03-2018 IPR003000 Sirtuin family GO:0070403 CSW12_RS12325 ecf18456548b8eb09fe4b94cc4cb273a 245 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 9 242 62.593 T 29-03-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 CSW12_RS12325 ecf18456548b8eb09fe4b94cc4cb273a 245 SUPERFAMILY SSF52467 5 241 2.06E-76 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 Pfam PF00990 Diguanylate cyclase, GGDEF domain 481 636 1.9E-41 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 355 477 1.0E-17 T 29-03-2018 IPR000014 PAS domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 SMART SM00052 652 898 6.2E-109 T 29-03-2018 IPR001633 EAL domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 Pfam PF08448 PAS fold 368 471 4.6E-9 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 Gene3D G3DSA:3.30.450.20 321 483 5.0E-21 T 29-03-2018 CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 SUPERFAMILY SSF141868 657 905 1.31E-83 T 29-03-2018 IPR001633 EAL domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 SUPERFAMILY SSF55073 487 643 2.2E-42 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 SMART SM00267 470 642 9.4E-49 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 SMART SM00091 358 424 2.2E-6 T 29-03-2018 IPR000014 PAS domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 Gene3D G3DSA:3.30.70.270 484 649 3.0E-50 T 29-03-2018 CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 Gene3D G3DSA:3.20.20.450 650 909 7.7E-95 T 29-03-2018 IPR001633 EAL domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 479 640 4.9E-36 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 SUPERFAMILY SSF55785 345 468 4.89E-17 T 29-03-2018 IPR000014 PAS domain CSW12_RS09050 0b816d7c781b54e69e2d9eb596f69f76 909 Pfam PF00563 EAL domain 658 893 7.9E-70 T 29-03-2018 IPR001633 EAL domain CSW12_RS08590 f4f70e429d096f7bf24035f20573644e 257 SUPERFAMILY SSF53098 62 256 1.02E-71 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS08590 f4f70e429d096f7bf24035f20573644e 257 Pfam PF01351 Ribonuclease HII 75 249 4.1E-35 T 29-03-2018 IPR024567 Ribonuclease HII/HIII domain CSW12_RS08590 f4f70e429d096f7bf24035f20573644e 257 Hamap MF_00052_B Ribonuclease HII [rnhB]. 73 251 37.059 T 29-03-2018 IPR022898 Ribonuclease HII GO:0004523 CSW12_RS08590 f4f70e429d096f7bf24035f20573644e 257 Gene3D G3DSA:3.30.420.10 48 257 3.0E-75 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 55 79 9.2E-16 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 9.2E-16 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 9.2E-16 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 9.2E-16 T 29-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 5.1E-60 T 29-03-2018 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 117 3.5E-19 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 Pfam PF00361 Proton-conducting membrane transporter 130 419 6.6E-90 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26235 bc6868b0d2de051b75191162db10068b 620 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 5 612 7.1E-204 T 29-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 PIRSF PIRSF000379 8 749 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 Gene3D G3DSA:3.20.70.20 2 749 4.8E-300 T 29-03-2018 CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 SUPERFAMILY SSF51998 8 749 1.05E-287 T 29-03-2018 CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 Pfam PF02901 Pyruvate formate lyase-like 24 608 2.2E-209 T 29-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 ProSitePatterns PS00850 Glycine radical domain signature. 719 727 - T 29-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 Pfam PF01228 Glycine radical 624 730 3.8E-44 T 29-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CSW12_RS01150 dd79e0326f51e7b3b6ecd0a3837416b9 749 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 749 0.0 T 29-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CSW12_RS13155 c8d100b183188b9cbfbc05dfbaa7a0b6 290 Pfam PF00005 ABC transporter 20 156 9.8E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS13155 c8d100b183188b9cbfbc05dfbaa7a0b6 290 Gene3D G3DSA:3.40.50.300 2 247 2.9E-42 T 29-03-2018 CSW12_RS13155 c8d100b183188b9cbfbc05dfbaa7a0b6 290 SUPERFAMILY SSF52540 3 221 3.4E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13155 c8d100b183188b9cbfbc05dfbaa7a0b6 290 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS13155 c8d100b183188b9cbfbc05dfbaa7a0b6 290 SMART SM00382 28 206 8.0E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS11510 9890a6bb08dc6df5e4f7e5d3c4a9b93d 112 Pfam PF13034 Protein of unknown function (DUF3895) 30 104 8.5E-34 T 29-03-2018 IPR024995 Protein of unknown function DUF3895 CSW12_RS15445 cc1174d6528f41e9ba3d49dc83d4db93 76 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 14 69 8.2E-14 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS15445 cc1174d6528f41e9ba3d49dc83d4db93 76 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 29 38 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS09825 8b4c1852a91744df89f93a5c6f42c558 568 Gene3D G3DSA:3.40.190.10 226 320 7.1E-20 T 29-03-2018 CSW12_RS09825 8b4c1852a91744df89f93a5c6f42c558 568 Gene3D G3DSA:3.90.76.10 65 225 7.4E-44 T 29-03-2018 CSW12_RS09825 8b4c1852a91744df89f93a5c6f42c558 568 Gene3D G3DSA:3.10.105.10 321 537 4.5E-45 T 29-03-2018 CSW12_RS09825 8b4c1852a91744df89f93a5c6f42c558 568 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 485 8.0E-79 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS09825 8b4c1852a91744df89f93a5c6f42c558 568 PIRSF PIRSF002741 2 568 5.0E-107 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS09825 8b4c1852a91744df89f93a5c6f42c558 568 SUPERFAMILY SSF53850 54 563 1.48E-124 T 29-03-2018 CSW12_RS26210 f6cc210756b2c0ee387a2bfb7da39fa7 434 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 407 2.6E-117 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS26210 f6cc210756b2c0ee387a2bfb7da39fa7 434 Gene3D G3DSA:3.65.10.10 21 221 1.4E-47 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS26210 f6cc210756b2c0ee387a2bfb7da39fa7 434 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.533 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS26210 f6cc210756b2c0ee387a2bfb7da39fa7 434 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 1.8E-176 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS26210 f6cc210756b2c0ee387a2bfb7da39fa7 434 Gene3D G3DSA:3.65.10.10 222 419 6.6E-50 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS26210 f6cc210756b2c0ee387a2bfb7da39fa7 434 SUPERFAMILY SSF55205 2 418 9.65E-143 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CSW12_RS22510 432c41f854f9fd0fe90754b93c2092a7 312 SMART SM00382 161 285 0.0012 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS22510 432c41f854f9fd0fe90754b93c2092a7 312 Pfam PF01695 IstB-like ATP binding protein 151 275 2.8E-13 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CSW12_RS22510 432c41f854f9fd0fe90754b93c2092a7 312 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 1.2E-30 T 29-03-2018 IPR009928 Primosomal DnaI, N-terminal CSW12_RS22510 432c41f854f9fd0fe90754b93c2092a7 312 SUPERFAMILY SSF52540 144 277 3.42E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22510 432c41f854f9fd0fe90754b93c2092a7 312 Gene3D G3DSA:3.40.50.300 108 303 2.8E-20 T 29-03-2018 CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 SUPERFAMILY SSF46894 126 226 1.05E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 Gene3D G3DSA:3.40.50.2300 1 131 5.2E-28 T 29-03-2018 CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 Gene3D G3DSA:1.10.10.10 132 232 6.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 SMART SM00448 2 112 3.0E-27 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 5.3E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 SUPERFAMILY SSF52172 3 118 1.08E-32 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 SMART SM00862 150 225 2.8E-15 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS14750 5ae1e8967437745818892c003b373cc9 235 Pfam PF00072 Response regulator receiver domain 4 112 5.7E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 SUPERFAMILY SSF53822 61 325 7.26E-60 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 SUPERFAMILY SSF47413 1 59 4.78E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 4.0E-19 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 Gene3D G3DSA:1.10.260.40 3 58 6.3E-21 T 29-03-2018 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 SMART SM00354 1 71 2.7E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 Pfam PF13377 Periplasmic binding protein-like domain 167 325 7.5E-28 T 29-03-2018 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 Gene3D G3DSA:3.40.50.2300 59 169 1.5E-20 T 29-03-2018 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.3E-5 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS20650 34e25c014bdba80ff74c02bed7a22f47 325 Gene3D G3DSA:3.40.50.2300 170 308 5.4E-36 T 29-03-2018 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 Gene3D G3DSA:1.20.1250.20 9 200 4.1E-29 T 29-03-2018 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 Gene3D G3DSA:1.20.1250.20 202 404 3.9E-21 T 29-03-2018 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 Pfam PF07690 Major Facilitator Superfamily 24 331 9.9E-44 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 PRINTS PR01035 Tetracycline resistance protein signature 174 194 4.7E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 PRINTS PR01035 Tetracycline resistance protein signature 114 135 4.7E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 PRINTS PR01035 Tetracycline resistance protein signature 26 42 4.7E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 PRINTS PR01035 Tetracycline resistance protein signature 378 397 4.7E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 PRINTS PR01035 Tetracycline resistance protein signature 56 75 4.7E-6 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS25135 8c751f92c528401e0cb089f1e32424f6 404 SUPERFAMILY SSF103473 11 396 1.44E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS02675 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 SMART SM00530 5 60 3.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02675 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 Gene3D G3DSA:1.10.10.10 2 25 7.4E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02675 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 Gene3D G3DSA:3.30.1190.10 26 66 1.1E-14 T 29-03-2018 CSW12_RS02675 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 SUPERFAMILY SSF47413 5 64 2.36E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02675 148c428a9fb6e9ec1d8af3ac0a7a9a51 66 Pfam PF01381 Helix-turn-helix 6 56 6.7E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15825 99599c05cbb06c72f9295d0a6ee38589 186 Gene3D G3DSA:2.160.20.50 17 58 2.0E-6 T 29-03-2018 CSW12_RS15825 99599c05cbb06c72f9295d0a6ee38589 186 Gene3D G3DSA:2.60.120.40 59 186 6.7E-23 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS15825 99599c05cbb06c72f9295d0a6ee38589 186 SUPERFAMILY SSF49842 89 168 1.4E-5 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS07625 fb0d16c5004535dc07cf69bc7ff03e51 254 Gene3D G3DSA:2.60.40.1240 68 254 2.6E-8 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS09155 d1f30d167c0a03a832fccf7a6dad9ea5 271 Pfam PF01226 Formate/nitrite transporter 9 248 3.0E-75 T 29-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CSW12_RS09155 d1f30d167c0a03a832fccf7a6dad9ea5 271 Gene3D G3DSA:1.20.1080.10 3 263 2.7E-84 T 29-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CSW12_RS09155 d1f30d167c0a03a832fccf7a6dad9ea5 271 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 161 171 - T 29-03-2018 IPR024002 Formate/nitrite transporter, conserved site CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 Gene3D G3DSA:3.20.20.70 1 221 1.5E-70 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 216 2.2E-57 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 SUPERFAMILY SSF51569 1 219 4.19E-74 T 29-03-2018 CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 ProSitePatterns PS00958 Transaldolase active site. 87 104 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 219 1.7E-81 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CSW12_RS11025 af9c103b495e51e37c7704e2e67fa803 222 Hamap MF_00494 Probable transaldolase [tal]. 1 221 45.67 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CSW12_RS03245 2170af436791e64b040c9ba6759f4e6d 159 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 158 1.5E-67 T 29-03-2018 IPR032836 DsrE2-like family CSW12_RS03245 2170af436791e64b040c9ba6759f4e6d 159 Gene3D G3DSA:3.40.1260.10 1 159 2.4E-53 T 29-03-2018 CSW12_RS03245 2170af436791e64b040c9ba6759f4e6d 159 SUPERFAMILY SSF75169 101 157 2.88E-23 T 29-03-2018 IPR027396 DsrEFH-like CSW12_RS03245 2170af436791e64b040c9ba6759f4e6d 159 SUPERFAMILY SSF75169 5 51 2.88E-23 T 29-03-2018 IPR027396 DsrEFH-like CSW12_RS14330 5d89d58e4be10772e4760d6aaf023e0e 176 Pfam PF14091 Domain of unknown function (DUF4269) 21 167 2.1E-60 T 29-03-2018 IPR025365 Protein of unknown function DUF4269 CSW12_RS21025 2299d88ceacdd82651e537df99a14dbd 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 18 224 1.4E-65 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS21025 2299d88ceacdd82651e537df99a14dbd 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 230 284 3.4E-21 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS21025 2299d88ceacdd82651e537df99a14dbd 292 PIRSF PIRSF006483 1 291 5.1E-90 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 SUPERFAMILY SSF46785 9 138 2.66E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 SMART SM00347 27 124 2.5E-21 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 1.1E-6 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 Pfam PF01047 MarR family 34 85 3.2E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS18165 ed2162aed4a27b94935c104a8a13e1e7 147 Gene3D G3DSA:1.10.10.10 2 146 2.3E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:1.10.8.60 321 388 3.0E-19 T 29-03-2018 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:1.10.10.60 389 447 4.5E-9 T 29-03-2018 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 SUPERFAMILY SSF46689 401 447 6.27E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:3.30.450.20 9 144 9.2E-18 T 29-03-2018 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 Pfam PF00158 Sigma-54 interaction domain 149 315 1.3E-66 T 29-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 Pfam PF13426 PAS domain 23 117 2.2E-10 T 29-03-2018 IPR000014 PAS domain CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 Gene3D G3DSA:3.40.50.300 145 320 3.7E-26 T 29-03-2018 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 SUPERFAMILY SSF52540 148 388 1.14E-64 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 124 1.1E-9 T 29-03-2018 IPR000014 PAS domain CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 235 250 - T 29-03-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 SMART SM00382 168 312 3.2E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 SUPERFAMILY SSF55785 11 111 5.23E-14 T 29-03-2018 IPR000014 PAS domain CSW12_RS00450 8f528d6ab799c765937ee1789a8b87bd 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 29-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CSW12_RS30835 ff9626d1507c2d4e33a049258ce53f47 366 Gene3D G3DSA:1.25.40.10 6 145 5.5E-28 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS30835 ff9626d1507c2d4e33a049258ce53f47 366 Gene3D G3DSA:1.25.40.10 148 210 6.8E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS30835 ff9626d1507c2d4e33a049258ce53f47 366 SUPERFAMILY SSF48452 126 265 1.99E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS30835 ff9626d1507c2d4e33a049258ce53f47 366 Gene3D G3DSA:1.25.40.10 211 366 5.9E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 Gene3D G3DSA:3.30.160.70 2 85 1.5E-10 T 29-03-2018 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 92 170 1.2E-30 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 SUPERFAMILY SSF53155 8 86 1.16E-13 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 86 1.7E-8 T 29-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 169 1.1E-34 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 29-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 SUPERFAMILY SSF46767 89 171 8.5E-31 T 29-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CSW12_RS09085 0186d1ba3fa4b3d6c8cc96dd454bdc48 176 Gene3D G3DSA:1.10.10.10 86 172 2.2E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21115 0d00963e60a200c2c9a6c320310d82be 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 98 2.8E-16 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CSW12_RS21115 0d00963e60a200c2c9a6c320310d82be 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CSW12_RS21115 0d00963e60a200c2c9a6c320310d82be 132 SUPERFAMILY SSF53927 3 130 2.06E-48 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS21115 0d00963e60a200c2c9a6c320310d82be 132 Gene3D G3DSA:3.40.140.10 1 132 1.4E-53 T 29-03-2018 CSW12_RS21115 0d00963e60a200c2c9a6c320310d82be 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 129 1.4E-46 T 29-03-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 CSW12_RS27100 ff8b8e7f6a8ebc6a6f46d9d4a01c6906 215 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 7 214 7.8E-61 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CSW12_RS27100 ff8b8e7f6a8ebc6a6f46d9d4a01c6906 215 Pfam PF03006 Haemolysin-III related 4 207 4.7E-47 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CSW12_RS25230 4db4ccc0293819009a6642f92db5a691 185 SUPERFAMILY SSF52499 2 180 2.75E-47 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS25230 4db4ccc0293819009a6642f92db5a691 185 Pfam PF00857 Isochorismatase family 4 148 2.3E-37 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS25230 4db4ccc0293819009a6642f92db5a691 185 Gene3D G3DSA:3.40.50.850 1 185 6.4E-42 T 29-03-2018 CSW12_RS29160 2a430c87fdf703be7174af967dbc069c 473 Pfam PF01609 Transposase DDE domain 120 386 2.3E-43 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CSW12_RS29160 2a430c87fdf703be7174af967dbc069c 473 SUPERFAMILY SSF53098 32 468 2.88E-64 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29160 2a430c87fdf703be7174af967dbc069c 473 Gene3D G3DSA:3.90.350.10 184 367 1.5E-20 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CSW12_RS15040 0d6248e109b0fb99cf14a640c7881ac1 322 PIRSF PIRSF037004 1 316 1.1E-123 T 29-03-2018 IPR017087 Uncharacterised conserved protein UCP037004 CSW12_RS15040 0d6248e109b0fb99cf14a640c7881ac1 322 Pfam PF08349 Protein of unknown function (DUF1722) 191 307 1.7E-40 T 29-03-2018 IPR013560 Domain of unknown function DUF1722 CSW12_RS15040 0d6248e109b0fb99cf14a640c7881ac1 322 Pfam PF04463 Protein of unknown function (DUF523) 9 149 1.1E-35 T 29-03-2018 IPR007553 Domain of unknown function DUF523 CSW12_RS03215 8153c40a009ee6dd60664e77fcd831da 87 Pfam PF02583 Metal-sensitive transcriptional repressor 4 84 1.4E-25 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CSW12_RS16215 f207125619e649b6d85428313c0dfb8f 99 Gene3D G3DSA:1.10.10.10 1 99 1.4E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16215 f207125619e649b6d85428313c0dfb8f 99 SUPERFAMILY SSF46785 13 86 2.03E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16215 f207125619e649b6d85428313c0dfb8f 99 Pfam PF01022 Bacterial regulatory protein, arsR family 26 66 1.4E-11 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS16215 f207125619e649b6d85428313c0dfb8f 99 SMART SM00418 19 97 7.3E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS03385 d98437596c11a4560e4aecc09f1a966d 259 SUPERFAMILY SSF158430 4 123 6.02E-36 T 29-03-2018 CSW12_RS03385 d98437596c11a4560e4aecc09f1a966d 259 SUPERFAMILY SSF158430 125 258 6.15E-42 T 29-03-2018 CSW12_RS03385 d98437596c11a4560e4aecc09f1a966d 259 Pfam PF11155 Domain of unknown function (DUF2935) 127 245 6.3E-27 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CSW12_RS03385 d98437596c11a4560e4aecc09f1a966d 259 Pfam PF11155 Domain of unknown function (DUF2935) 8 114 4.1E-21 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 SUPERFAMILY SSF58104 160 428 4.97E-64 T 29-03-2018 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 SUPERFAMILY SSF58104 101 127 4.97E-64 T 29-03-2018 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 SMART SM00283 147 429 1.8E-52 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 227 382 4.9E-38 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 SMART SM00304 72 125 4.3E-10 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 Pfam PF00672 HAMP domain 74 121 3.2E-11 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 Gene3D G3DSA:1.10.287.950 69 191 5.4E-8 T 29-03-2018 CSW12_RS00690 6e66f54e96520f39bfd38e14061cbb36 430 Gene3D G3DSA:1.10.287.950 192 430 2.6E-44 T 29-03-2018 CSW12_RS22545 501e8242f97856d3b28b41ed776c6531 210 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 5 210 2.4E-74 T 29-03-2018 IPR014205 Sporulation protein YtaF CSW12_RS22545 501e8242f97856d3b28b41ed776c6531 210 Pfam PF02659 Putative manganese efflux pump 127 208 2.1E-10 T 29-03-2018 IPR003810 Putative manganese efflux pump CSW12_RS22545 501e8242f97856d3b28b41ed776c6531 210 Pfam PF02659 Putative manganese efflux pump 6 83 6.4E-10 T 29-03-2018 IPR003810 Putative manganese efflux pump CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 Gene3D G3DSA:3.40.50.300 298 559 7.3E-49 T 29-03-2018 CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 Gene3D G3DSA:3.40.50.300 2 297 4.3E-57 T 29-03-2018 CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 Pfam PF12848 ABC transporter 230 324 4.5E-23 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 SUPERFAMILY SSF52540 6 244 2.3E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 Pfam PF00005 ABC transporter 351 478 3.7E-20 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 Pfam PF00005 ABC transporter 20 191 2.5E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 SUPERFAMILY SSF52540 323 534 2.43E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 SMART SM00382 28 243 8.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28565 d7d2d0b7ef5d0d5fae8ee2844f93af8c 626 SMART SM00382 359 522 3.2E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS12435 57e06fc502c326ba83772c04a905c43f 247 Gene3D G3DSA:3.60.21.10 1 245 3.8E-38 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS12435 57e06fc502c326ba83772c04a905c43f 247 PIRSF PIRSF000883 2 243 1.4E-56 T 29-03-2018 IPR011152 Phosphoesterase MJ0912 CSW12_RS12435 57e06fc502c326ba83772c04a905c43f 247 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 192 4.9E-24 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CSW12_RS12435 57e06fc502c326ba83772c04a905c43f 247 SUPERFAMILY SSF56300 1 232 7.45E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 SUPERFAMILY SSF50800 69 164 1.92E-26 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 10 337 1.4E-132 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 Pfam PF00224 Pyruvate kinase, barrel domain 10 334 5.4E-115 T 29-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 266 290 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 58 74 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 310 326 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 214 240 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 183 197 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 291 309 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 PRINTS PR01050 Pyruvate kinase family signature 241 265 2.3E-56 T 29-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 Gene3D G3DSA:3.20.20.60 6 155 5.2E-28 T 29-03-2018 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 Gene3D G3DSA:3.20.20.60 156 332 1.8E-56 T 29-03-2018 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 SUPERFAMILY SSF51621 153 334 4.54E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS11300 e9c564a35be7bf5d3432d7f23fbf2efd 356 SUPERFAMILY SSF51621 9 73 4.54E-84 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS14795 2267230207c6fb810a6dcf3f3219074f 165 Gene3D G3DSA:3.30.240.20 76 145 2.2E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS14795 2267230207c6fb810a6dcf3f3219074f 165 Pfam PF04239 Protein of unknown function (DUF421) 82 151 2.4E-16 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CSW12_RS15410 30bafecede741fde3de5eb03ef509298 375 Gene3D G3DSA:1.20.1170.10 30 375 1.9E-44 T 29-03-2018 CSW12_RS15410 30bafecede741fde3de5eb03ef509298 375 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 46 223 1.5E-59 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS15410 30bafecede741fde3de5eb03ef509298 375 SUPERFAMILY SSF58100 33 369 1.36E-102 T 29-03-2018 CSW12_RS25890 b6440a0f5c4e51f2225402f3e4567d54 105 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 104 5.0E-45 T 29-03-2018 CSW12_RS25890 b6440a0f5c4e51f2225402f3e4567d54 105 Pfam PF09685 Domain of unknown function (DUF4870) 6 98 3.4E-8 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 CSW12_RS07540 d161d702f55fece894e0de6933f1d262 110 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 1.7E-23 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS07540 d161d702f55fece894e0de6933f1d262 110 SUPERFAMILY SSF46785 11 105 1.22E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07540 d161d702f55fece894e0de6933f1d262 110 Gene3D G3DSA:1.10.10.10 1 98 1.2E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13815 59f2e98f085fbb6a3c83cf352093f40e 198 Gene3D G3DSA:2.60.20.10 106 198 1.9E-8 T 29-03-2018 CSW12_RS30515 b2ca76260b1adf1fc5a7999e4781c012 141 Pfam PF13411 MerR HTH family regulatory protein 9 75 5.0E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS30515 b2ca76260b1adf1fc5a7999e4781c012 141 Gene3D G3DSA:1.10.1660.10 1 141 7.0E-16 T 29-03-2018 CSW12_RS30515 b2ca76260b1adf1fc5a7999e4781c012 141 SUPERFAMILY SSF46955 8 129 1.56E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS01435 9f697d53285a442e52442b7ab13b8e2b 162 Gene3D G3DSA:3.40.1280.10 1 159 2.8E-45 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CSW12_RS01435 9f697d53285a442e52442b7ab13b8e2b 162 Pfam PF00588 SpoU rRNA Methylase family 3 145 3.8E-36 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CSW12_RS01435 9f697d53285a442e52442b7ab13b8e2b 162 PIRSF PIRSF029256 2 157 2.0E-68 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CSW12_RS01435 9f697d53285a442e52442b7ab13b8e2b 162 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.875 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CSW12_RS01435 9f697d53285a442e52442b7ab13b8e2b 162 SUPERFAMILY SSF75217 3 155 5.23E-46 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CSW12_RS01435 9f697d53285a442e52442b7ab13b8e2b 162 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 2.6E-67 T 29-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CSW12_RS19510 dde96b4566adfbce2d20c653fd7500ed 451 Pfam PF01554 MatE 255 404 7.6E-18 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS19510 dde96b4566adfbce2d20c653fd7500ed 451 Pfam PF01554 MatE 22 183 4.4E-27 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS19510 dde96b4566adfbce2d20c653fd7500ed 451 PIRSF PIRSF006603 1 440 1.7E-73 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS19510 dde96b4566adfbce2d20c653fd7500ed 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 416 2.4E-53 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS00645 18b55060bc978a56c5c5ec89d011df02 210 Gene3D G3DSA:3.50.30.50 1 210 6.3E-61 T 29-03-2018 CSW12_RS00645 18b55060bc978a56c5c5ec89d011df02 210 Pfam PF04199 Putative cyclase 4 151 1.2E-26 T 29-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CSW12_RS00645 18b55060bc978a56c5c5ec89d011df02 210 SUPERFAMILY SSF102198 1 208 2.09E-60 T 29-03-2018 CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 SUPERFAMILY SSF90002 221 315 2.09E-25 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 SUPERFAMILY SSF52540 2 211 3.21E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 SMART SM00833 221 315 3.3E-8 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 221 315 2.4E-22 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 Gene3D G3DSA:3.30.1220.10 203 316 5.0E-28 T 29-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 3 183 9.8E-56 T 29-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CSW12_RS17750 61fe1960c00890aa3ac86ce7bcf62a3e 316 Gene3D G3DSA:3.40.50.300 1 202 7.8E-48 T 29-03-2018 CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 Pfam PF04542 Sigma-70 region 2 24 84 8.6E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 Pfam PF08281 Sigma-70, region 4 109 160 5.4E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 SUPERFAMILY SSF88946 22 81 7.85E-9 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 Gene3D G3DSA:1.10.10.10 89 200 2.1E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 SUPERFAMILY SSF88659 101 166 5.61E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 161 4.1E-15 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS13720 ac85307f17a4de178ebf4337b44ea8e2 228 Gene3D G3DSA:1.10.1740.10 19 83 3.8E-9 T 29-03-2018 CSW12_RS01030 ca8cff09904095f5c1cc4b49807d786a 287 Gene3D G3DSA:1.10.340.30 117 234 5.0E-25 T 29-03-2018 CSW12_RS01030 ca8cff09904095f5c1cc4b49807d786a 287 Gene3D G3DSA:1.10.1670.10 237 287 8.7E-9 T 29-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CSW12_RS01030 ca8cff09904095f5c1cc4b49807d786a 287 SMART SM00478 127 286 1.8E-12 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS01030 ca8cff09904095f5c1cc4b49807d786a 287 SUPERFAMILY SSF48150 113 284 2.44E-36 T 29-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CSW12_RS01030 ca8cff09904095f5c1cc4b49807d786a 287 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 266 8.5E-17 T 29-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CSW12_RS13395 a56fb4b56fec2ea57495c21b77b2cb92 254 SUPERFAMILY SSF53335 11 240 4.89E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS13395 a56fb4b56fec2ea57495c21b77b2cb92 254 Pfam PF13649 Methyltransferase domain 41 136 7.9E-13 T 29-03-2018 CSW12_RS13395 a56fb4b56fec2ea57495c21b77b2cb92 254 Gene3D G3DSA:3.40.50.150 22 253 8.5E-21 T 29-03-2018 CSW12_RS08660 99b3090eed953da9d2547be3d81c25e8 258 SUPERFAMILY SSF64005 25 251 2.49E-90 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CSW12_RS08660 99b3090eed953da9d2547be3d81c25e8 258 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 257 40.689 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CSW12_RS08660 99b3090eed953da9d2547be3d81c25e8 258 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 256 1.7E-87 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CSW12_RS08660 99b3090eed953da9d2547be3d81c25e8 258 Gene3D G3DSA:3.40.1180.10 15 258 2.7E-97 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CSW12_RS08660 99b3090eed953da9d2547be3d81c25e8 258 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 29-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CSW12_RS08660 99b3090eed953da9d2547be3d81c25e8 258 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 256 2.0E-86 T 29-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CSW12_RS10305 fd934bfd7c60202f3813617316987dad 347 Gene3D G3DSA:1.10.3290.10 19 295 1.5E-36 T 29-03-2018 IPR003812 Fido domain CSW12_RS10305 fd934bfd7c60202f3813617316987dad 347 Pfam PF02661 Fic/DOC family 109 215 1.8E-12 T 29-03-2018 IPR003812 Fido domain CSW12_RS10305 fd934bfd7c60202f3813617316987dad 347 SUPERFAMILY SSF140931 93 286 4.84E-25 T 29-03-2018 IPR003812 Fido domain CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 Pfam PF01264 Chorismate synthase 1 364 2.8E-126 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 Gene3D G3DSA:3.60.150.10 1 389 1.6E-144 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 37.15 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 SUPERFAMILY SSF103263 1 388 1.96E-151 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 1.6E-132 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 PIRSF PIRSF001456 1 385 8.9E-134 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS20020 ad3dcf544f613c81974de9ee3462d40c 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS24745 1ae6c83523afaa2e544f8c5eb62b85a6 114 Gene3D G3DSA:3.30.1050.10 2 111 1.6E-5 T 29-03-2018 IPR003033 SCP2 sterol-binding domain CSW12_RS15475 fceb566dfc69904581fa62094a64ef68 524 PIRSF PIRSF005690 30 524 4.9E-189 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS15475 fceb566dfc69904581fa62094a64ef68 524 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 44 513 1.2E-187 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS15945 aef0968599dd698f72482cabdab05270 183 Gene3D G3DSA:3.40.630.30 2 182 2.9E-25 T 29-03-2018 CSW12_RS15945 aef0968599dd698f72482cabdab05270 183 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 1.1E-26 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS15945 aef0968599dd698f72482cabdab05270 183 SUPERFAMILY SSF55729 1 174 9.9E-46 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS23715 8ba0e3153aaf315b7dced73caced1e7a 342 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 215 1.2E-52 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS23715 8ba0e3153aaf315b7dced73caced1e7a 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 6 329 9.1E-91 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS23715 8ba0e3153aaf315b7dced73caced1e7a 342 PIRSF PIRSF000267 1 342 9.8E-128 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS17570 8fbfbd945d240860d95d4f8dde79b805 384 SUPERFAMILY SSF53187 232 377 8.79E-11 T 29-03-2018 CSW12_RS17570 8fbfbd945d240860d95d4f8dde79b805 384 Gene3D G3DSA:3.40.630.40 43 381 5.5E-14 T 29-03-2018 CSW12_RS17570 8fbfbd945d240860d95d4f8dde79b805 384 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 97 372 4.1E-69 T 29-03-2018 IPR010897 Sporulation stage II, protein P CSW12_RS17570 8fbfbd945d240860d95d4f8dde79b805 384 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 173 377 2.6E-72 T 29-03-2018 IPR010897 Sporulation stage II, protein P CSW12_RS07300 fed432ba7ac59b7b7ecea113d37f3342 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 106 1.4E-36 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CSW12_RS07300 fed432ba7ac59b7b7ecea113d37f3342 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 8.4E-46 T 29-03-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 CSW12_RS07300 fed432ba7ac59b7b7ecea113d37f3342 116 SUPERFAMILY SSF52091 3 111 3.53E-31 T 29-03-2018 IPR002645 STAS domain CSW12_RS07300 fed432ba7ac59b7b7ecea113d37f3342 116 Pfam PF01740 STAS domain 5 107 8.0E-23 T 29-03-2018 IPR002645 STAS domain CSW12_RS07300 fed432ba7ac59b7b7ecea113d37f3342 116 Gene3D G3DSA:3.30.750.24 3 114 8.8E-24 T 29-03-2018 IPR002645 STAS domain CSW12_RS28395 a36602d687d24e496ca5fba4b552fe5a 257 Pfam PF00005 ABC transporter 25 176 5.7E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28395 a36602d687d24e496ca5fba4b552fe5a 257 Gene3D G3DSA:3.40.50.300 2 256 6.5E-73 T 29-03-2018 CSW12_RS28395 a36602d687d24e496ca5fba4b552fe5a 257 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS28395 a36602d687d24e496ca5fba4b552fe5a 257 SUPERFAMILY SSF52540 5 248 6.77E-72 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28395 a36602d687d24e496ca5fba4b552fe5a 257 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 255 2.8E-6 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS28395 a36602d687d24e496ca5fba4b552fe5a 257 SMART SM00382 34 225 7.8E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS10805 5b251abebe9916316417d88794a73600 91 SMART SM00418 13 91 3.8E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10805 5b251abebe9916316417d88794a73600 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 9.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10805 5b251abebe9916316417d88794a73600 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 9.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10805 5b251abebe9916316417d88794a73600 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 9.0E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10805 5b251abebe9916316417d88794a73600 91 Pfam PF12840 Helix-turn-helix domain 12 71 1.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10805 5b251abebe9916316417d88794a73600 91 SUPERFAMILY SSF46785 4 90 8.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10805 5b251abebe9916316417d88794a73600 91 Gene3D G3DSA:1.10.10.10 1 87 3.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PIRSF PIRSF005419 4 688 1.0E-181 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 Pfam PF00771 FHIPEP family 20 679 3.3E-198 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 173 190 8.2E-44 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 224 238 8.2E-44 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 63 82 8.2E-44 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 124 140 8.2E-44 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 26 39 8.2E-44 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS19220 3a4a25a6fbeb4f8f71654de1bfb09a71 688 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 161 8.2E-44 T 29-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CSW12_RS02950 2d9810f2e48bbbe1874d8f66e47b748d 231 PIRSF PIRSF003170 1 218 2.0E-32 T 29-03-2018 IPR026285 TenA_E protein CSW12_RS02950 2d9810f2e48bbbe1874d8f66e47b748d 231 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 217 1.6E-73 T 29-03-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 CSW12_RS02950 2d9810f2e48bbbe1874d8f66e47b748d 231 Pfam PF03070 TENA/THI-4/PQQC family 10 216 9.4E-61 T 29-03-2018 IPR004305 Thiaminase-2/PQQC CSW12_RS02950 2d9810f2e48bbbe1874d8f66e47b748d 231 Gene3D G3DSA:1.20.910.10 1 224 5.4E-62 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CSW12_RS02950 2d9810f2e48bbbe1874d8f66e47b748d 231 SUPERFAMILY SSF48613 1 215 1.47E-75 T 29-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CSW12_RS08275 dd3c1380208e56c9945d1f3258ae974f 168 Pfam PF05103 DivIVA protein 3 133 6.8E-52 T 29-03-2018 IPR007793 DivIVA family CSW12_RS08275 dd3c1380208e56c9945d1f3258ae974f 168 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.7E-17 T 29-03-2018 IPR019933 DivIVA domain CSW12_RS28270 d36f412a6f6288874c6eb42288a9edd2 273 Gene3D G3DSA:3.40.1700.10 112 239 8.6E-36 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS28270 d36f412a6f6288874c6eb42288a9edd2 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 236 1.5E-43 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS28270 d36f412a6f6288874c6eb42288a9edd2 273 SUPERFAMILY SSF143597 40 240 7.45E-70 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS28270 d36f412a6f6288874c6eb42288a9edd2 273 PIRSF PIRSF004793 3 269 1.2E-98 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CSW12_RS28270 d36f412a6f6288874c6eb42288a9edd2 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 254 33.734 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CSW12_RS28270 d36f412a6f6288874c6eb42288a9edd2 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 3 254 1.4E-96 T 29-03-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 CSW12_RS16795 87bd4788499ee459397be6487ae6ef93 153 SUPERFAMILY SSF49764 30 145 1.33E-27 T 29-03-2018 IPR008978 HSP20-like chaperone CSW12_RS16795 87bd4788499ee459397be6487ae6ef93 153 Pfam PF00011 Hsp20/alpha crystallin family 57 147 1.1E-15 T 29-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CSW12_RS16795 87bd4788499ee459397be6487ae6ef93 153 Gene3D G3DSA:2.60.40.790 1 152 1.8E-27 T 29-03-2018 IPR008978 HSP20-like chaperone CSW12_RS10255 98c17950988abbded3d5369c0d25224d 362 SUPERFAMILY SSF51735 12 340 1.64E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10255 98c17950988abbded3d5369c0d25224d 362 Pfam PF16363 GDP-mannose 4,6 dehydratase 16 332 4.5E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10255 98c17950988abbded3d5369c0d25224d 362 Gene3D G3DSA:3.40.50.720 2 201 3.7E-27 T 29-03-2018 CSW12_RS10255 98c17950988abbded3d5369c0d25224d 362 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 10 360 3.0E-162 T 29-03-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 CSW12_RS10255 98c17950988abbded3d5369c0d25224d 362 Gene3D G3DSA:3.90.25.10 202 361 3.7E-23 T 29-03-2018 CSW12_RS01885 eba70209adf22b307700b700b6f1550e 323 Pfam PF01636 Phosphotransferase enzyme family 31 252 1.9E-24 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS01885 eba70209adf22b307700b700b6f1550e 323 Gene3D G3DSA:3.30.200.20 3 110 2.7E-10 T 29-03-2018 CSW12_RS01885 eba70209adf22b307700b700b6f1550e 323 SUPERFAMILY SSF56112 10 314 8.73E-45 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS01885 eba70209adf22b307700b700b6f1550e 323 Gene3D G3DSA:3.90.1200.10 125 314 1.8E-16 T 29-03-2018 CSW12_RS26705 27f29765cda31cb9dda7e2d8d9905793 230 Gene3D G3DSA:1.20.5.400 142 226 3.6E-4 T 29-03-2018 CSW12_RS26705 27f29765cda31cb9dda7e2d8d9905793 230 Gene3D G3DSA:1.10.10.60 1 99 2.0E-5 T 29-03-2018 CSW12_RS26705 27f29765cda31cb9dda7e2d8d9905793 230 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 79 5.2E-45 T 29-03-2018 IPR014243 Transcription factor, RsfA CSW12_RS26705 27f29765cda31cb9dda7e2d8d9905793 230 Pfam PF13921 Myb-like DNA-binding domain 8 57 3.1E-5 T 29-03-2018 CSW12_RS13360 61992970c500d86fff06cb763b276428 157 SUPERFAMILY SSF55729 8 148 1.22E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13360 61992970c500d86fff06cb763b276428 157 Pfam PF13673 Acetyltransferase (GNAT) domain 27 139 4.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13360 61992970c500d86fff06cb763b276428 157 Gene3D G3DSA:3.40.630.30 1 156 1.1E-17 T 29-03-2018 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 417 2.1E-132 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 Gene3D G3DSA:1.10.240.10 224 324 3.3E-37 T 29-03-2018 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 Gene3D G3DSA:3.10.290.10 325 420 1.4E-22 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 Gene3D G3DSA:3.40.50.620 3 223 3.6E-69 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 SUPERFAMILY SSF52374 1 323 3.94E-113 T 29-03-2018 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 3.6E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 181 203 3.6E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 3.6E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 3.6E-29 T 29-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.458 T 29-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 Pfam PF01479 S4 domain 356 395 1.2E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 SMART SM00363 352 410 0.0074 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 1.6E-83 T 29-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS25160 50e853e5bc5c916063c19a495c661c7a 420 SUPERFAMILY SSF55174 321 417 3.93E-23 T 29-03-2018 CSW12_RS05525 6a642813575bd2471f67bbe6744ac1bc 132 SUPERFAMILY SSF46458 7 124 6.3E-40 T 29-03-2018 IPR009050 Globin-like CSW12_RS05525 6a642813575bd2471f67bbe6744ac1bc 132 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 29-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CSW12_RS05525 6a642813575bd2471f67bbe6744ac1bc 132 Gene3D G3DSA:1.10.490.10 3 130 6.6E-34 T 29-03-2018 CSW12_RS05525 6a642813575bd2471f67bbe6744ac1bc 132 Pfam PF01152 Bacterial-like globin 9 123 8.2E-34 T 29-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 SUPERFAMILY SSF46955 6 112 7.69E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 Gene3D G3DSA:1.10.1660.10 65 131 6.6E-6 T 29-03-2018 CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 Gene3D G3DSA:1.10.1660.10 3 64 6.6E-20 T 29-03-2018 CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 SMART SM00422 7 77 2.2E-14 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 Pfam PF06445 GyrI-like small molecule binding domain 161 273 5.3E-12 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 SUPERFAMILY SSF55136 126 274 3.49E-41 T 29-03-2018 CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 Pfam PF13411 MerR HTH family regulatory protein 7 76 9.3E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 Gene3D G3DSA:3.20.80.10 132 275 1.1E-25 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS19515 acb42af00ebff1f272f98794258be559 276 SMART SM00871 123 274 6.0E-11 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 6.7E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 6.7E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 6.7E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 6.7E-22 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.816 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 Pfam PF01084 Ribosomal protein S18 23 72 1.4E-28 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 SUPERFAMILY SSF46911 5 75 4.58E-31 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 77 9.0E-24 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 Gene3D G3DSA:4.10.640.10 2 77 3.8E-34 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 29-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27225 9661c8c3063cfe890c3436e87bdab330 77 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 75 7.7E-37 T 29-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS24840 a2909e3a17f08133d48ea377461bdf1d 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 142 155 1.6E-8 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS24840 a2909e3a17f08133d48ea377461bdf1d 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 115 132 1.6E-8 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS24840 a2909e3a17f08133d48ea377461bdf1d 279 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 65 76 1.6E-8 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS24840 a2909e3a17f08133d48ea377461bdf1d 279 Gene3D G3DSA:3.40.710.10 22 279 1.2E-38 T 29-03-2018 CSW12_RS24840 a2909e3a17f08133d48ea377461bdf1d 279 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 31 257 5.2E-46 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS24840 a2909e3a17f08133d48ea377461bdf1d 279 SUPERFAMILY SSF56601 7 277 9.51E-53 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 SUPERFAMILY SSF51735 117 266 9.92E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 Gene3D G3DSA:3.40.50.720 140 313 8.2E-37 T 29-03-2018 CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 SMART SM00829 10 327 1.7E-51 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 Gene3D G3DSA:3.90.180.10 1 139 3.2E-39 T 29-03-2018 CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.9E-8 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 SUPERFAMILY SSF50129 1 155 8.37E-37 T 29-03-2018 IPR011032 GroES-like CSW12_RS11000 b0213d92ba1546317fb4fa9aa4336051 331 Pfam PF13602 Zinc-binding dehydrogenase 189 327 5.1E-28 T 29-03-2018 CSW12_RS11755 ef8235be44747e3e7514d93349326ef8 609 PIRSF PIRSF018968 1 414 1.9E-36 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS11755 ef8235be44747e3e7514d93349326ef8 609 PIRSF PIRSF018968 415 607 6.0E-23 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS11755 ef8235be44747e3e7514d93349326ef8 609 Pfam PF02687 FtsX-like permease family 84 179 4.8E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS27990 9449923bc88e8a1500a28c380f65608d 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 6.9E-84 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27990 9449923bc88e8a1500a28c380f65608d 207 SUPERFAMILY SSF52166 1 206 4.71E-86 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CSW12_RS27990 9449923bc88e8a1500a28c380f65608d 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 38.224 T 29-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27990 9449923bc88e8a1500a28c380f65608d 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 7.6E-74 T 29-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CSW12_RS27990 9449923bc88e8a1500a28c380f65608d 207 Gene3D G3DSA:3.40.1370.10 146 205 1.2E-17 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CSW12_RS27990 9449923bc88e8a1500a28c380f65608d 207 Gene3D G3DSA:3.40.1370.10 2 145 8.9E-60 T 29-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CSW12_RS03615 d0780d7ab58596008d79f11df3de35af 265 Gene3D G3DSA:3.40.190.10 141 259 7.0E-30 T 29-03-2018 CSW12_RS03615 d0780d7ab58596008d79f11df3de35af 265 Gene3D G3DSA:3.40.190.10 26 140 2.3E-30 T 29-03-2018 CSW12_RS03615 d0780d7ab58596008d79f11df3de35af 265 SMART SM00079 43 261 0.0016 T 29-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CSW12_RS03615 d0780d7ab58596008d79f11df3de35af 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 4.4E-61 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS03615 d0780d7ab58596008d79f11df3de35af 265 SUPERFAMILY SSF53850 1 262 3.53E-67 T 29-03-2018 CSW12_RS03615 d0780d7ab58596008d79f11df3de35af 265 SMART SM00062 43 262 1.4E-72 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 Pfam PF00303 Thymidylate synthase 7 318 8.7E-122 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 169 188 9.6E-50 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 195 210 9.6E-50 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 46 67 9.6E-50 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 213 239 9.6E-50 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 PRINTS PR00108 Thymidylate synthase family signature 251 268 9.6E-50 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 SUPERFAMILY SSF55831 3 318 3.27E-139 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 7 318 1.0E-170 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 Hamap MF_00008 Thymidylate synthase [thyA]. 5 318 40.786 T 29-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 Gene3D G3DSA:3.30.572.10 1 318 4.4E-137 T 29-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS16860 8efe59999cf48844f7f6e9b298664a0d 318 ProSitePatterns PS00091 Thymidylate synthase active site. 180 208 - T 29-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CSW12_RS07195 1d8cf0e3f2b8bba27f8907d00da27cfe 44 Pfam PF13072 Protein of unknown function (DUF3936) 1 37 2.8E-22 T 29-03-2018 IPR025177 Protein of unknown function DUF3936 CSW12_RS20140 547539ec9bf361a2a880e64c499b163b 242 SUPERFAMILY SSF52540 1 206 2.38E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20140 547539ec9bf361a2a880e64c499b163b 242 PIRSF PIRSF006755 1 230 1.5E-62 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CSW12_RS20140 547539ec9bf361a2a880e64c499b163b 242 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 219 29.642 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CSW12_RS20140 547539ec9bf361a2a880e64c499b163b 242 Pfam PF13500 AAA domain 4 203 1.7E-45 T 29-03-2018 CSW12_RS20140 547539ec9bf361a2a880e64c499b163b 242 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 172 3.1E-51 T 29-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CSW12_RS20140 547539ec9bf361a2a880e64c499b163b 242 Gene3D G3DSA:3.40.50.300 1 215 3.2E-54 T 29-03-2018 CSW12_RS06070 471081f1191077e39cb072d5324f3b9a 240 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 10 90 5.7E-24 T 29-03-2018 IPR010627 Peptidase A24A, N-terminal CSW12_RS06070 471081f1191077e39cb072d5324f3b9a 240 Pfam PF01478 Type IV leader peptidase family 103 204 8.1E-14 T 29-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 TIGRFAM TIGR00492 alr: alanine racemase 7 375 2.9E-122 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 SMART SM01005 248 376 1.1E-70 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 Gene3D G3DSA:3.20.20.10 7 231 1.3E-51 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 Pfam PF00842 Alanine racemase, C-terminal domain 248 375 3.3E-47 T 29-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 SUPERFAMILY SSF50621 243 381 1.12E-52 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 164 175 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 207 234 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 358 371 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 281 296 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 302 319 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 69 87 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 264 279 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 130 142 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 PRINTS PR00992 Alanine racemase signature 33 49 2.8E-62 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 29-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 Gene3D G3DSA:2.40.37.10 232 385 2.9E-63 T 29-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 SUPERFAMILY SSF51419 13 249 1.13E-66 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 Pfam PF01168 Alanine racemase, N-terminal domain 13 234 8.6E-68 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS17495 313766fc8aa383a8adbdd31f0398335f 391 Hamap MF_01201 Alanine racemase. 6 376 34.626 T 29-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS00810 2fea8e4f15bf6dbde5299d52dd5b45a8 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS00810 2fea8e4f15bf6dbde5299d52dd5b45a8 249 SUPERFAMILY SSF52540 4 227 4.64E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00810 2fea8e4f15bf6dbde5299d52dd5b45a8 249 Pfam PF00005 ABC transporter 19 157 9.4E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS00810 2fea8e4f15bf6dbde5299d52dd5b45a8 249 Gene3D G3DSA:3.40.50.300 2 238 7.6E-55 T 29-03-2018 CSW12_RS00810 2fea8e4f15bf6dbde5299d52dd5b45a8 249 SMART SM00382 28 207 1.9E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 SUPERFAMILY SSF52172 1 125 4.27E-40 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 SUPERFAMILY SSF46894 123 221 1.08E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 SMART SM00862 145 220 3.1E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 Gene3D G3DSA:3.40.50.2300 1 120 1.3E-36 T 29-03-2018 CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 Pfam PF00072 Response regulator receiver domain 4 112 1.1E-26 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.8E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 Gene3D G3DSA:1.10.10.10 121 223 3.6E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01570 618a0e313b8b504d83619434aad2be01 223 SMART SM00448 1 111 1.5E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS19375 3df63c2141682e2bcaf8ba4d159924af 458 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 22 115 4.9E-12 T 29-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CSW12_RS19375 3df63c2141682e2bcaf8ba4d159924af 458 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 234 436 4.8E-23 T 29-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 PIRSF PIRSF039101 2 499 1.2E-199 T 29-03-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 494 3.3E-82 T 29-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 1.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 1.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 1.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 379 395 1.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 1.6E-39 T 29-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 8 497 7.9E-223 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 Gene3D G3DSA:2.40.50.140 9 149 1.3E-39 T 29-03-2018 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 Pfam PF01336 OB-fold nucleic acid binding domain 63 140 1.6E-14 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 SUPERFAMILY SSF50249 8 149 2.36E-43 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 497 46.235 T 29-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 SUPERFAMILY SSF55681 156 495 4.58E-123 T 29-03-2018 CSW12_RS27740 43848f36b96eb2f2687359841e3fa711 499 Gene3D G3DSA:3.30.930.10 150 494 5.5E-109 T 29-03-2018 CSW12_RS13330 96240eb4965356a1ac64195d8eb0ce5c 286 Gene3D G3DSA:3.40.50.10170 1 156 1.0E-41 T 29-03-2018 CSW12_RS13330 96240eb4965356a1ac64195d8eb0ce5c 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 282 3.0E-82 T 29-03-2018 IPR003797 DegV CSW12_RS13330 96240eb4965356a1ac64195d8eb0ce5c 286 Gene3D G3DSA:3.30.1180.10 157 283 3.7E-41 T 29-03-2018 CSW12_RS13330 96240eb4965356a1ac64195d8eb0ce5c 286 SUPERFAMILY SSF82549 1 282 2.43E-88 T 29-03-2018 CSW12_RS13330 96240eb4965356a1ac64195d8eb0ce5c 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 281 3.5E-95 T 29-03-2018 IPR003797 DegV CSW12_RS23485 23bece496eb5285e03836c88b1170a27 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 9 44 2.9E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS23485 23bece496eb5285e03836c88b1170a27 170 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 5.2E-8 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS23485 23bece496eb5285e03836c88b1170a27 170 Gene3D G3DSA:2.160.10.10 1 170 5.3E-45 T 29-03-2018 CSW12_RS23485 23bece496eb5285e03836c88b1170a27 170 SUPERFAMILY SSF51161 2 168 6.24E-51 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS18530 a66cf3825bb9ad4a31aaf9461c488dff 406 Pfam PF07690 Major Facilitator Superfamily 22 315 1.2E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS18530 a66cf3825bb9ad4a31aaf9461c488dff 406 Gene3D G3DSA:1.20.1250.20 1 189 1.1E-19 T 29-03-2018 CSW12_RS18530 a66cf3825bb9ad4a31aaf9461c488dff 406 Gene3D G3DSA:1.20.1250.20 217 397 1.9E-13 T 29-03-2018 CSW12_RS18530 a66cf3825bb9ad4a31aaf9461c488dff 406 SUPERFAMILY SSF103473 4 391 8.76E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 SMART SM00357 4 67 3.3E-32 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 6.7E-33 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 Gene3D G3DSA:2.40.50.140 2 67 1.2E-27 T 29-03-2018 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 SUPERFAMILY SSF50249 2 66 2.03E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 PRINTS PR00050 Cold shock protein signature 25 34 1.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 PRINTS PR00050 Cold shock protein signature 5 20 1.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 PRINTS PR00050 Cold shock protein signature 40 58 1.5E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 PIRSF PIRSF002599 1 67 4.9E-25 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS25680 86d8cca0fb089969f79aa71fd6b63346 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CSW12_RS19815 830f891f30bbb2260462c0f5c4a1a589 63 Pfam PF14178 YppF-like protein 1 58 3.6E-29 T 29-03-2018 IPR025553 YppF-like protein CSW12_RS19815 830f891f30bbb2260462c0f5c4a1a589 63 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 57 3.0E-6 T 29-03-2018 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 29-03-2018 IPR014762 DNA mismatch repair, conserved site CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 SMART SM00853 461 603 3.8E-52 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 SMART SM01340 208 326 2.0E-56 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 120 4.3E-12 T 29-03-2018 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 Gene3D G3DSA:3.30.230.10 198 326 1.1E-30 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 SUPERFAMILY SSF54211 189 326 7.97E-38 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 Gene3D G3DSA:3.30.565.10 2 197 1.3E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 SUPERFAMILY SSF118116 457 645 1.7E-54 T 29-03-2018 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 4.1E-37 T 29-03-2018 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 Pfam PF08676 MutL C terminal dimerisation domain 461 603 5.2E-46 T 29-03-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 SUPERFAMILY SSF55874 3 212 6.16E-52 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 643 27.42 T 29-03-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CSW12_RS08940 2cc1d38621e66de58afb1b1d83f94639 647 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 3.1E-99 T 29-03-2018 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 PIRSF PIRSF002599 1 66 6.7E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.2E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 PRINTS PR00050 Cold shock protein signature 39 57 4.3E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 PRINTS PR00050 Cold shock protein signature 4 19 4.3E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 PRINTS PR00050 Cold shock protein signature 24 33 4.3E-19 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 SUPERFAMILY SSF50249 1 64 6.38E-26 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 SMART SM00357 3 66 3.7E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CSW12_RS24045 346f9ddffafaf6fabe18f9aac7cfc312 66 Gene3D G3DSA:2.40.50.140 1 66 4.6E-29 T 29-03-2018 CSW12_RS05625 04caac34ffe233661c4eb1d81f5607a2 284 Pfam PF04321 RmlD substrate binding domain 4 280 4.6E-101 T 29-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CSW12_RS05625 04caac34ffe233661c4eb1d81f5607a2 284 Gene3D G3DSA:3.40.50.720 1 170 3.2E-26 T 29-03-2018 CSW12_RS05625 04caac34ffe233661c4eb1d81f5607a2 284 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 278 7.7E-101 T 29-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CSW12_RS05625 04caac34ffe233661c4eb1d81f5607a2 284 Gene3D G3DSA:3.90.25.10 171 197 3.6E-8 T 29-03-2018 CSW12_RS05625 04caac34ffe233661c4eb1d81f5607a2 284 SUPERFAMILY SSF51735 4 278 1.04E-90 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS05625 04caac34ffe233661c4eb1d81f5607a2 284 Gene3D G3DSA:3.90.25.10 198 267 1.7E-21 T 29-03-2018 CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 3 182 4.0E-42 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 Pfam PF00145 C-5 cytosine-specific DNA methylase 2 179 1.5E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 Gene3D G3DSA:3.40.50.150 1 161 1.7E-36 T 29-03-2018 CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 SUPERFAMILY SSF53335 2 213 6.64E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 144 157 3.9E-8 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 93 107 3.9E-8 T 29-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CSW12_RS30080 b5205c562e0d23c28ceb79545e24428b 218 Gene3D G3DSA:3.90.120.10 162 218 2.1E-6 T 29-03-2018 CSW12_RS18885 c2c09f8815eae257d9f00b4e87e42512 415 Pfam PF04286 Protein of unknown function (DUF445) 40 415 1.1E-85 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CSW12_RS23015 532d82f32ed296bcefb6f99836232fff 308 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 121 8.9E-26 T 29-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CSW12_RS23015 532d82f32ed296bcefb6f99836232fff 308 Gene3D G3DSA:3.40.50.720 1 129 9.3E-31 T 29-03-2018 CSW12_RS23015 532d82f32ed296bcefb6f99836232fff 308 SUPERFAMILY SSF51735 4 138 3.78E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS23015 532d82f32ed296bcefb6f99836232fff 308 SUPERFAMILY SSF55347 126 266 3.76E-42 T 29-03-2018 CSW12_RS23015 532d82f32ed296bcefb6f99836232fff 308 Gene3D G3DSA:3.30.360.10 130 305 1.2E-16 T 29-03-2018 CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 SUPERFAMILY SSF55021 337 415 8.24E-11 T 29-03-2018 CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 314 1.3E-76 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 Gene3D G3DSA:3.40.50.1100 20 179 1.9E-41 T 29-03-2018 CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 327 418 1.7E-26 T 29-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 TIGRFAM TIGR02079 THD1: threonine dehydratase 13 420 1.3E-193 T 29-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 SUPERFAMILY SSF53686 11 362 3.93E-100 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS18590 6c58a63277fe0d949cc5538864208b2c 420 Gene3D G3DSA:3.40.1020.10 218 420 2.4E-37 T 29-03-2018 CSW12_RS02925 e7965cdc9cf5853d5ae4a8df47a11e8d 139 SMART SM00116 75 122 7.2E-12 T 29-03-2018 IPR000644 CBS domain CSW12_RS02925 e7965cdc9cf5853d5ae4a8df47a11e8d 139 SMART SM00116 11 58 0.003 T 29-03-2018 IPR000644 CBS domain CSW12_RS02925 e7965cdc9cf5853d5ae4a8df47a11e8d 139 Pfam PF00571 CBS domain 69 118 7.8E-13 T 29-03-2018 IPR000644 CBS domain CSW12_RS02925 e7965cdc9cf5853d5ae4a8df47a11e8d 139 Pfam PF00571 CBS domain 4 54 7.5E-11 T 29-03-2018 IPR000644 CBS domain CSW12_RS02925 e7965cdc9cf5853d5ae4a8df47a11e8d 139 Gene3D G3DSA:3.10.580.10 1 120 2.0E-28 T 29-03-2018 CSW12_RS02925 e7965cdc9cf5853d5ae4a8df47a11e8d 139 SUPERFAMILY SSF54631 1 117 9.6E-33 T 29-03-2018 CSW12_RS25215 f19a4a521e31cc2027804be872f383e9 171 SUPERFAMILY SSF55729 3 162 1.21E-41 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS25215 f19a4a521e31cc2027804be872f383e9 171 Pfam PF13302 Acetyltransferase (GNAT) domain 5 138 7.8E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS25215 f19a4a521e31cc2027804be872f383e9 171 Gene3D G3DSA:3.40.630.30 3 171 1.8E-33 T 29-03-2018 CSW12_RS14490 0bb0652d8e747214102a6d55cc8cbb14 135 Pfam PF09685 Domain of unknown function (DUF4870) 6 133 2.2E-7 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 CSW12_RS19680 7476a89a7ff77f230365744d415d1197 241 SUPERFAMILY SSF81653 126 231 7.59E-22 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS19680 7476a89a7ff77f230365744d415d1197 241 Pfam PF00122 E1-E2 ATPase 125 232 6.5E-23 T 29-03-2018 CSW12_RS19680 7476a89a7ff77f230365744d415d1197 241 SUPERFAMILY SSF81665 37 76 1.31E-5 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS19680 7476a89a7ff77f230365744d415d1197 241 Gene3D G3DSA:2.70.150.10 32 237 5.5E-29 T 29-03-2018 CSW12_RS19680 7476a89a7ff77f230365744d415d1197 241 Pfam PF00690 Cation transporter/ATPase, N-terminus 39 76 3.0E-6 T 29-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CSW12_RS03095 3ec2827dab0b4523f4bd776d95dfa08e 139 Pfam PF02600 Disulfide bond formation protein DsbB 10 115 1.0E-10 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CSW12_RS03095 3ec2827dab0b4523f4bd776d95dfa08e 139 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 4 139 24.55 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CSW12_RS03095 3ec2827dab0b4523f4bd776d95dfa08e 139 PIRSF PIRSF036659 1 139 9.1E-60 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CSW12_RS03095 3ec2827dab0b4523f4bd776d95dfa08e 139 SUPERFAMILY SSF158442 12 135 1.16E-28 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CSW12_RS03095 3ec2827dab0b4523f4bd776d95dfa08e 139 Gene3D G3DSA:1.20.1550.10 1 137 2.3E-24 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 SUPERFAMILY SSF51735 163 393 3.38E-76 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 Gene3D G3DSA:3.40.50.10380 6 160 1.5E-38 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 SUPERFAMILY SSF53223 10 161 1.94E-55 T 29-03-2018 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 Pfam PF03949 Malic enzyme, NAD binding domain 165 385 8.2E-25 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 Gene3D G3DSA:3.40.50.720 161 398 4.9E-77 T 29-03-2018 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 PRINTS PR00072 Malic enzyme signature 190 206 7.4E-9 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 PRINTS PR00072 Malic enzyme signature 80 102 7.4E-9 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 PRINTS PR00072 Malic enzyme signature 159 175 7.4E-9 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 SMART SM00919 163 386 1.2E-122 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 SMART SM01274 18 151 3.1E-81 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 PIRSF PIRSF000106 25 398 3.3E-80 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS01610 da4e0538f466fe5a4bec2cfe5e79a15e 399 Pfam PF00390 Malic enzyme, N-terminal domain 20 151 1.6E-28 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS30565 1fc2831ef250cb5dade16772487f2573 601 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 41 418 1.6E-106 T 29-03-2018 IPR030931 Group II intron reverse transcriptase/maturase CSW12_RS30565 1fc2831ef250cb5dade16772487f2573 601 Gene3D G3DSA:3.30.70.270 119 334 6.6E-29 T 29-03-2018 CSW12_RS30565 1fc2831ef250cb5dade16772487f2573 601 SMART SM00507 509 560 7.9E-7 T 29-03-2018 IPR003615 HNH nuclease CSW12_RS30565 1fc2831ef250cb5dade16772487f2573 601 Gene3D G3DSA:3.40.1800.10 499 575 1.0E-7 T 29-03-2018 CSW12_RS30565 1fc2831ef250cb5dade16772487f2573 601 SUPERFAMILY SSF56672 16 346 8.26E-44 T 29-03-2018 CSW12_RS30565 1fc2831ef250cb5dade16772487f2573 601 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 99 334 6.6E-39 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS01895 a4b6db09d0ba5d0d1b790330bb394049 300 SUPERFAMILY SSF52540 59 292 6.46E-83 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01895 a4b6db09d0ba5d0d1b790330bb394049 300 Gene3D G3DSA:3.40.50.300 56 298 3.2E-78 T 29-03-2018 CSW12_RS01895 a4b6db09d0ba5d0d1b790330bb394049 300 PIRSF PIRSF039085 56 299 1.3E-116 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CSW12_RS01895 a4b6db09d0ba5d0d1b790330bb394049 300 ProSitePatterns PS00211 ABC transporters family signature. 195 209 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS01895 a4b6db09d0ba5d0d1b790330bb394049 300 SMART SM00382 84 271 2.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS01895 a4b6db09d0ba5d0d1b790330bb394049 300 Pfam PF00005 ABC transporter 75 223 3.5E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25675 26196f2773fe1a57fad7580012654ce0 180 Gene3D G3DSA:3.30.160.100 1 96 7.0E-34 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CSW12_RS25675 26196f2773fe1a57fad7580012654ce0 180 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 3.1E-32 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CSW12_RS25675 26196f2773fe1a57fad7580012654ce0 180 SUPERFAMILY SSF69754 2 103 8.37E-37 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CSW12_RS25675 26196f2773fe1a57fad7580012654ce0 180 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 180 25.332 T 29-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CSW12_RS25675 26196f2773fe1a57fad7580012654ce0 180 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 99 1.4E-34 T 29-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CSW12_RS25675 26196f2773fe1a57fad7580012654ce0 180 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 121 176 8.8E-30 T 29-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CSW12_RS08065 43092dd06387d854d0bd7ec7d745401e 344 Gene3D G3DSA:3.40.33.10 217 342 1.3E-17 T 29-03-2018 IPR014044 CAP domain CSW12_RS08065 43092dd06387d854d0bd7ec7d745401e 344 SUPERFAMILY SSF55797 223 341 6.67E-23 T 29-03-2018 IPR014044 CAP domain CSW12_RS08065 43092dd06387d854d0bd7ec7d745401e 344 Pfam PF14504 CAP-associated N-terminal 60 199 1.8E-47 T 29-03-2018 IPR029410 CAP-associated domain CSW12_RS08065 43092dd06387d854d0bd7ec7d745401e 344 Pfam PF00188 Cysteine-rich secretory protein family 230 334 2.6E-17 T 29-03-2018 IPR014044 CAP domain CSW12_RS08060 3ae93ef20ba5de508cc2c46746f604c6 121 Gene3D G3DSA:3.30.310.100 1 116 4.4E-37 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CSW12_RS08060 3ae93ef20ba5de508cc2c46746f604c6 121 Pfam PF08868 YugN-like family 6 93 3.9E-14 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CSW12_RS08060 3ae93ef20ba5de508cc2c46746f604c6 121 SUPERFAMILY SSF160755 1 114 8.24E-39 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CSW12_RS06180 a712843b8988b3e6bfc46619cd3800f0 394 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 125 378 7.7E-19 T 29-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 CSW12_RS06180 a712843b8988b3e6bfc46619cd3800f0 394 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 101 1.9E-14 T 29-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CSW12_RS06180 a712843b8988b3e6bfc46619cd3800f0 394 Gene3D G3DSA:3.40.50.720 2 133 1.9E-7 T 29-03-2018 CSW12_RS06180 a712843b8988b3e6bfc46619cd3800f0 394 SUPERFAMILY SSF51735 2 157 6.68E-13 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS06180 a712843b8988b3e6bfc46619cd3800f0 394 Gene3D G3DSA:3.30.360.10 134 317 1.5E-24 T 29-03-2018 CSW12_RS09535 01c2faa51d3be41b7659c0e4aa0bc5f3 312 Gene3D G3DSA:3.10.180.10 1 146 1.6E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09535 01c2faa51d3be41b7659c0e4aa0bc5f3 312 Gene3D G3DSA:3.10.180.10 147 311 6.3E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09535 01c2faa51d3be41b7659c0e4aa0bc5f3 312 SUPERFAMILY SSF54593 5 278 1.32E-46 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09535 01c2faa51d3be41b7659c0e4aa0bc5f3 312 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 266 2.7E-34 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 Pfam PF00072 Response regulator receiver domain 3 113 1.2E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 SUPERFAMILY SSF52172 1 178 1.34E-41 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 Gene3D G3DSA:3.40.50.2300 1 119 4.1E-38 T 29-03-2018 CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 SMART SM00448 1 112 1.7E-42 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 Gene3D G3DSA:1.10.10.10 120 224 3.1E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 5.1E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS11875 b8844eb2bea0af107f5e695d1865ab42 224 SMART SM00862 145 220 7.9E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS30695 430bce2536862e4f4a06287d43863cd9 193 Gene3D G3DSA:3.40.1050.10 1 192 1.2E-36 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS30695 430bce2536862e4f4a06287d43863cd9 193 Pfam PF00484 Carbonic anhydrase 34 177 5.3E-18 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS30695 430bce2536862e4f4a06287d43863cd9 193 SMART SM00947 26 182 9.3E-37 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS30695 430bce2536862e4f4a06287d43863cd9 193 SUPERFAMILY SSF53056 2 181 3.66E-42 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS28535 fd24d4a9f52d46d7009d51abaa16331c 549 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 213 474 7.8E-68 T 29-03-2018 IPR018763 Protein of unknown function DUF2334 CSW12_RS28535 fd24d4a9f52d46d7009d51abaa16331c 549 Gene3D G3DSA:3.20.20.370 75 509 1.7E-20 T 29-03-2018 CSW12_RS28535 fd24d4a9f52d46d7009d51abaa16331c 549 SUPERFAMILY SSF88713 339 402 1.06E-8 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS28535 fd24d4a9f52d46d7009d51abaa16331c 549 SUPERFAMILY SSF88713 209 292 1.06E-8 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS09245 4a3edd7f219a1a2958fda373006c4544 321 Gene3D G3DSA:1.10.150.130 1 103 8.0E-14 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS09245 4a3edd7f219a1a2958fda373006c4544 321 SUPERFAMILY SSF47823 15 110 8.24E-7 T 29-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CSW12_RS09245 4a3edd7f219a1a2958fda373006c4544 321 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 11 86 4.2E-7 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CSW12_RS09245 4a3edd7f219a1a2958fda373006c4544 321 SUPERFAMILY SSF56349 117 317 1.77E-19 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS09245 4a3edd7f219a1a2958fda373006c4544 321 Pfam PF00589 Phage integrase family 150 312 3.1E-9 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS09245 4a3edd7f219a1a2958fda373006c4544 321 Gene3D G3DSA:1.10.443.10 117 321 3.2E-14 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 Gene3D G3DSA:3.30.1390.10 49 119 1.4E-31 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 54 119 6.0E-17 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 53 119 8.9E-32 T 29-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 48 1.1E-20 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 SUPERFAMILY SSF54736 49 119 7.15E-26 T 29-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 Gene3D G3DSA:1.20.5.710 1 48 1.5E-18 T 29-03-2018 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 119 5.7E-50 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 SUPERFAMILY SSF48300 1 55 1.07E-16 T 29-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27930 489e26424ca923853bbcdfdc192f6f87 119 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 119 25.897 T 29-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS29520 b0a2985153cbad3f39a3e0db7644541b 392 SUPERFAMILY SSF56973 120 319 1.57E-6 T 29-03-2018 CSW12_RS29520 b0a2985153cbad3f39a3e0db7644541b 392 Gene3D G3DSA:2.170.15.10 151 362 6.0E-7 T 29-03-2018 CSW12_RS22590 663c17f4b70baf6e96afd04d1d0d0392 435 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 27 422 1.3E-123 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CSW12_RS22590 663c17f4b70baf6e96afd04d1d0d0392 435 SUPERFAMILY SSF53659 6 427 6.48E-142 T 29-03-2018 CSW12_RS22590 663c17f4b70baf6e96afd04d1d0d0392 435 Gene3D G3DSA:3.40.718.10 15 429 9.2E-138 T 29-03-2018 CSW12_RS22590 663c17f4b70baf6e96afd04d1d0d0392 435 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 312 331 - T 29-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CSW12_RS22590 663c17f4b70baf6e96afd04d1d0d0392 435 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 6 428 1.7E-220 T 29-03-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CSW12_RS22590 663c17f4b70baf6e96afd04d1d0d0392 435 SMART SM01329 26 423 1.2E-185 T 29-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 70 603 2.2E-182 T 29-03-2018 CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 SUPERFAMILY SSF56601 268 657 1.62E-120 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 SUPERFAMILY SSF56601 216 238 1.62E-120 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 Gene3D G3DSA:3.40.710.10 254 660 2.6E-112 T 29-03-2018 CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 Pfam PF00905 Penicillin binding protein transpeptidase domain 325 600 2.4E-33 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 Pfam PF00912 Transglycosylase 61 234 2.1E-61 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 Gene3D G3DSA:1.10.3810.10 52 253 1.2E-74 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS26655 6bcd496d5cd563f702bd9b7f139b6d1e 683 SUPERFAMILY SSF53955 47 261 2.0E-74 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS23495 f4dd1fa8d001de3524fd84d17cc0ab15 380 Pfam PF13439 Glycosyltransferase Family 4 14 177 1.0E-22 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CSW12_RS23495 f4dd1fa8d001de3524fd84d17cc0ab15 380 SUPERFAMILY SSF53756 2 372 1.06E-80 T 29-03-2018 CSW12_RS23495 f4dd1fa8d001de3524fd84d17cc0ab15 380 Gene3D G3DSA:3.40.50.2000 188 353 1.2E-40 T 29-03-2018 CSW12_RS23495 f4dd1fa8d001de3524fd84d17cc0ab15 380 Pfam PF00534 Glycosyl transferases group 1 189 347 3.6E-32 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS23495 f4dd1fa8d001de3524fd84d17cc0ab15 380 Gene3D G3DSA:3.40.50.2000 11 187 7.2E-13 T 29-03-2018 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 Gene3D G3DSA:1.10.10.10 127 215 3.9E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 SUPERFAMILY SSF52172 2 134 2.99E-37 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 SUPERFAMILY SSF46894 146 215 1.29E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 Pfam PF00072 Response regulator receiver domain 5 117 1.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 SMART SM00421 152 209 7.1E-26 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 209 2.4E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 SMART SM00448 3 116 6.4E-36 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 Gene3D G3DSA:3.40.50.2300 2 126 5.3E-38 T 29-03-2018 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.7E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.7E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.7E-15 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS26840 c0ac5bc6cfbaae329023dfd6ba50b22b 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS30780 a51abe09cbd29e47b772a76377480acb 74 Pfam PF01381 Helix-turn-helix 13 59 4.4E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30780 a51abe09cbd29e47b772a76377480acb 74 SUPERFAMILY SSF47413 10 59 1.85E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS30780 a51abe09cbd29e47b772a76377480acb 74 SMART SM00530 10 66 0.0096 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30780 a51abe09cbd29e47b772a76377480acb 74 Gene3D G3DSA:1.10.260.40 2 74 7.9E-8 T 29-03-2018 CSW12_RS26015 6d819139b00eb2282cc8c04cbb67f2f3 158 PIRSF PIRSF011560 1 158 2.2E-56 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CSW12_RS26015 6d819139b00eb2282cc8c04cbb67f2f3 158 Pfam PF06338 ComK protein 6 155 4.1E-48 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CSW12_RS12800 b4ebef772e87f5ebd8bfb4dc54b53c97 313 SUPERFAMILY SSF100950 65 308 3.81E-62 T 29-03-2018 CSW12_RS12800 b4ebef772e87f5ebd8bfb4dc54b53c97 313 Gene3D G3DSA:3.40.50.1360 63 307 2.8E-32 T 29-03-2018 CSW12_RS12800 b4ebef772e87f5ebd8bfb4dc54b53c97 313 Pfam PF04198 Putative sugar-binding domain 65 307 2.0E-65 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CSW12_RS12800 b4ebef772e87f5ebd8bfb4dc54b53c97 313 Gene3D G3DSA:1.10.10.60 4 57 1.3E-11 T 29-03-2018 CSW12_RS26890 2cd66bff3bee97dd7a2f82ee15385f5e 490 Gene3D G3DSA:2.130.10.10 144 357 1.3E-5 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS26890 2cd66bff3bee97dd7a2f82ee15385f5e 490 Pfam PF13425 O-antigen ligase like membrane protein 9 489 1.6E-120 T 29-03-2018 CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SUPERFAMILY SSF55785 152 260 1.92E-17 T 29-03-2018 IPR000014 PAS domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SUPERFAMILY SSF55073 276 427 2.04E-36 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SMART SM00091 147 213 1.9E-8 T 29-03-2018 IPR000014 PAS domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SMART SM00091 19 88 16.0 T 29-03-2018 IPR000014 PAS domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SUPERFAMILY SSF55785 24 133 3.84E-9 T 29-03-2018 IPR000014 PAS domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 268 424 4.6E-27 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Gene3D G3DSA:3.30.450.20 21 144 6.8E-13 T 29-03-2018 CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Gene3D G3DSA:3.20.20.450 434 686 3.1E-93 T 29-03-2018 IPR001633 EAL domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SMART SM00267 259 427 4.4E-38 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Gene3D G3DSA:3.30.450.20 145 268 2.3E-18 T 29-03-2018 CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SUPERFAMILY SSF141868 442 688 5.49E-85 T 29-03-2018 IPR001633 EAL domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Pfam PF08448 PAS fold 157 260 3.1E-10 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Pfam PF08448 PAS fold 25 135 7.7E-26 T 29-03-2018 IPR013656 PAS fold-4 CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Pfam PF00563 EAL domain 443 677 1.3E-71 T 29-03-2018 IPR001633 EAL domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 422 2.7E-36 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 Gene3D G3DSA:3.30.70.270 269 433 1.2E-43 T 29-03-2018 CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 SMART SM00052 437 682 1.1E-112 T 29-03-2018 IPR001633 EAL domain CSW12_RS01440 146482f7c00638af8441d5e2a9b68717 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 260 5.7E-18 T 29-03-2018 IPR000014 PAS domain CSW12_RS08130 94f2a0cd1d3a7613de875591280fa206 166 Pfam PF02620 Uncharacterized ACR, COG1399 56 163 5.3E-22 T 29-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CSW12_RS15980 efdc1a77a3dcd3ba3949f9e6fcb48ff9 169 SUPERFAMILY SSF55729 3 160 2.53E-34 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS15980 efdc1a77a3dcd3ba3949f9e6fcb48ff9 169 Gene3D G3DSA:3.40.630.30 1 164 5.2E-31 T 29-03-2018 CSW12_RS15980 efdc1a77a3dcd3ba3949f9e6fcb48ff9 169 Pfam PF00583 Acetyltransferase (GNAT) family 43 135 8.6E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS26730 0c178d74686e6626d6adb3ef172375ad 140 Pfam PF07486 Cell Wall Hydrolase 24 129 5.0E-18 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CSW12_RS20085 3205172f2ec841571f316f4609fbc52a 81 Pfam PF10827 Protein of unknown function (DUF2552) 1 79 5.6E-44 T 29-03-2018 IPR020157 Uncharacterised protein family YqkC CSW12_RS20085 3205172f2ec841571f316f4609fbc52a 81 ProDom PD058987 CYTOSOLIC YQKC 21 81 3.0E-29 T 29-03-2018 IPR020157 Uncharacterised protein family YqkC CSW12_RS05060 776543bfda6fd867e15a1fc6c784c508 90 SMART SM00530 7 62 2.5E-4 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05060 776543bfda6fd867e15a1fc6c784c508 90 Pfam PF12844 Helix-turn-helix domain 8 63 4.2E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05060 776543bfda6fd867e15a1fc6c784c508 90 SUPERFAMILY SSF47413 3 70 2.67E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS05060 776543bfda6fd867e15a1fc6c784c508 90 Gene3D G3DSA:1.10.260.40 4 89 3.1E-14 T 29-03-2018 CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 4.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 4.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.9E-18 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 6.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 6.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 6.0E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 SUPERFAMILY SSF51735 3 236 1.02E-49 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 Pfam PF00106 short chain dehydrogenase 3 199 1.5E-40 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18970 43479b2ad8f12cf8d4d7eca918c4a237 236 Gene3D G3DSA:3.40.50.720 1 200 1.1E-46 T 29-03-2018 CSW12_RS00220 b9644b6872fd4ae4621806a5ff49d7d3 55 Pfam PF13128 Protein of unknown function (DUF3954) 2 50 1.4E-11 T 29-03-2018 IPR025017 Protein of unknown function DUF3954 CSW12_RS21280 07116b62720b44eacdcb3867a838df63 118 SUPERFAMILY SSF81301 1 113 8.34E-40 T 29-03-2018 CSW12_RS21280 07116b62720b44eacdcb3867a838df63 118 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 4.6E-26 T 29-03-2018 CSW12_RS21280 07116b62720b44eacdcb3867a838df63 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 1 105 24.564 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CSW12_RS21280 07116b62720b44eacdcb3867a838df63 118 Gene3D G3DSA:3.30.460.10 1 117 6.0E-32 T 29-03-2018 CSW12_RS21280 07116b62720b44eacdcb3867a838df63 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 9 104 3.1E-36 T 29-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 Pfam PF00535 Glycosyl transferase family 2 19 150 7.3E-23 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 Pfam PF00535 Glycosyl transferase family 2 325 460 1.9E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 Gene3D G3DSA:3.90.550.10 309 635 5.3E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 Gene3D G3DSA:3.90.550.10 1 308 2.2E-36 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 Pfam PF08241 Methyltransferase domain 722 770 4.6E-12 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 SUPERFAMILY SSF53448 322 550 8.53E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 Gene3D G3DSA:3.40.50.150 673 846 1.4E-18 T 29-03-2018 CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 SUPERFAMILY SSF53335 697 824 1.34E-19 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS18130 00591651f46e449c6ba8bb3939b05697 853 SUPERFAMILY SSF53448 16 246 3.19E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24700 37e9095b37896162a880fc2e2ae442c7 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 8.2E-76 T 29-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CSW12_RS24700 37e9095b37896162a880fc2e2ae442c7 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 1.3E-231 T 29-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CSW12_RS24700 37e9095b37896162a880fc2e2ae442c7 465 SUPERFAMILY SSF101960 32 462 1.03E-139 T 29-03-2018 CSW12_RS22315 ee477222977f5bcd532035e49dcb5f40 107 Hamap MF_01272 Heme oxygenase (staphylobilin-producing) [isdG]. 1 102 27.195 T 29-03-2018 IPR023953 Heme oxygenase IsdG GO:0004392|GO:0033212|GO:0055114 CSW12_RS22315 ee477222977f5bcd532035e49dcb5f40 107 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 1.3E-15 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CSW12_RS22315 ee477222977f5bcd532035e49dcb5f40 107 Gene3D G3DSA:3.30.70.100 1 106 4.1E-21 T 29-03-2018 CSW12_RS22315 ee477222977f5bcd532035e49dcb5f40 107 SUPERFAMILY SSF54909 1 97 8.05E-25 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS13525 f166105b0e50edca1c547c0a3ba71f6c 494 Pfam PF00171 Aldehyde dehydrogenase family 33 489 5.6E-188 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS13525 f166105b0e50edca1c547c0a3ba71f6c 494 Gene3D G3DSA:3.40.309.10 282 475 2.1E-79 T 29-03-2018 CSW12_RS13525 f166105b0e50edca1c547c0a3ba71f6c 494 SUPERFAMILY SSF53720 14 492 3.67E-182 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS13525 f166105b0e50edca1c547c0a3ba71f6c 494 Gene3D G3DSA:3.40.605.10 8 281 1.1E-111 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS13525 f166105b0e50edca1c547c0a3ba71f6c 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 Gene3D G3DSA:1.10.287.130 387 441 7.2E-16 T 29-03-2018 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 Pfam PF00512 His Kinase A (phospho-acceptor) domain 382 445 1.9E-15 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 SUPERFAMILY SSF158472 308 358 4.32E-8 T 29-03-2018 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 SMART SM00304 307 359 5.4E-8 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 SMART SM00388 381 445 1.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 545 555 2.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 580 2.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 541 2.3E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 SUPERFAMILY SSF55874 435 589 6.16E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 492 584 2.8E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 SMART SM00387 490 601 5.8E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 SUPERFAMILY SSF47384 367 445 3.73E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 Gene3D G3DSA:3.30.565.10 449 604 5.1E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06900 3b732fea643c8a2ffa742ab146090e63 604 Gene3D G3DSA:3.30.450.20 212 386 1.0E-4 T 29-03-2018 CSW12_RS17625 bc9a0228f64bd86e1dfc5498f1079592 160 Pfam PF04306 Protein of unknown function (DUF456) 21 156 5.6E-37 T 29-03-2018 IPR007403 Protein of unknown function DUF456 CSW12_RS25995 48bfc9fce09ac3ec92eb3dd768fe57d6 161 Pfam PF04892 VanZ like family 7 154 2.6E-23 T 29-03-2018 IPR006976 VanZ-like CSW12_RS25995 48bfc9fce09ac3ec92eb3dd768fe57d6 161 PIRSF PIRSF019083 1 161 2.1E-55 T 29-03-2018 IPR016747 Phosphotransbutyrylase CSW12_RS20705 a7dd8de577eb4cb95c1279a5da4960ad 124 Gene3D G3DSA:1.10.287.100 81 118 0.0013 T 29-03-2018 CSW12_RS20705 a7dd8de577eb4cb95c1279a5da4960ad 124 SUPERFAMILY SSF46785 6 80 1.27E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20705 a7dd8de577eb4cb95c1279a5da4960ad 124 SMART SM00345 17 76 4.1E-14 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS20705 a7dd8de577eb4cb95c1279a5da4960ad 124 Gene3D G3DSA:1.10.10.10 1 78 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20705 a7dd8de577eb4cb95c1279a5da4960ad 124 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 4.9E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 46 266 2.9E-48 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 SUPERFAMILY SSF56601 4 286 1.13E-58 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 308 376 6.6E-5 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 Gene3D G3DSA:3.40.710.10 23 310 1.5E-46 T 29-03-2018 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 Gene3D G3DSA:2.60.410.10 311 377 0.0014 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 125 142 3.1E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 152 165 3.1E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS05925 68e845a11c628ef16dadb007862c8399 428 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 75 86 3.1E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 7.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 7.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 7.4E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 Gene3D G3DSA:1.10.260.40 44 152 1.6E-5 T 29-03-2018 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 SUPERFAMILY SSF46689 8 70 1.85E-12 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 Gene3D G3DSA:1.10.10.60 3 43 2.4E-11 T 29-03-2018 CSW12_RS17610 8a5eb0912942647bb3d6382caaca857e 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS01910 4692d0e00fac47c73d0de8b9e407e374 214 SUPERFAMILY SSF161098 15 209 2.09E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01910 4692d0e00fac47c73d0de8b9e407e374 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 212 2.0E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01910 4692d0e00fac47c73d0de8b9e407e374 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 3.4E-28 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CSW12_RS01910 4692d0e00fac47c73d0de8b9e407e374 214 Gene3D G3DSA:1.10.3720.10 3 214 3.9E-41 T 29-03-2018 CSW12_RS23285 8601776e47127f00136bceaef9408c88 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 1.2E-23 T 29-03-2018 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 Reactome: R-HSA-947581 CSW12_RS23285 8601776e47127f00136bceaef9408c88 77 SUPERFAMILY SSF54285 1 77 8.04E-19 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CSW12_RS23285 8601776e47127f00136bceaef9408c88 77 Pfam PF02597 ThiS family 4 77 4.8E-18 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CSW12_RS23285 8601776e47127f00136bceaef9408c88 77 Gene3D G3DSA:3.10.20.30 2 77 2.2E-20 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 164.041 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 176 371 2.7E-70 T 29-03-2018 IPR020536 Thil, AANH domain GO:0004810 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 Gene3D G3DSA:3.40.50.620 176 404 6.9E-39 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 SMART SM00981 75 166 1.8E-19 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 SUPERFAMILY SSF52402 176 382 1.57E-54 T 29-03-2018 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 SUPERFAMILY SSF143437 4 174 3.31E-53 T 29-03-2018 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 Gene3D G3DSA:3.30.2300.10 84 164 7.2E-20 T 29-03-2018 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 Pfam PF02926 THUMP domain 35 162 1.1E-18 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 373 2.4E-129 T 29-03-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 CSW12_RS22880 d2f37a6ef25fade71492599534128736 404 Gene3D G3DSA:3.30.70.1510 6 82 1.3E-25 T 29-03-2018 CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 SUPERFAMILY SSF55681 3 318 7.66E-96 T 29-03-2018 CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 SUPERFAMILY SSF52954 329 421 3.62E-26 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 PIRSF PIRSF001549 1 422 3.8E-122 T 29-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 3.9E-155 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 Gene3D G3DSA:3.30.930.10 1 324 9.2E-72 T 29-03-2018 CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 Gene3D G3DSA:3.40.50.800 327 423 2.1E-22 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 Pfam PF03129 Anticodon binding domain 331 420 5.1E-18 T 29-03-2018 IPR004154 Anticodon-binding CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 33.719 T 29-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CSW12_RS21660 61ee50ce0f0d3362a60e33322527be50 423 Pfam PF13393 Histidyl-tRNA synthetase 8 313 3.8E-45 T 29-03-2018 CSW12_RS05165 18c03efcdea12a8fdd7c99eeaa7d087d 202 Gene3D G3DSA:3.20.16.10 15 202 9.4E-29 T 29-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CSW12_RS05165 18c03efcdea12a8fdd7c99eeaa7d087d 202 Pfam PF04586 Caudovirus prohead serine protease 8 165 1.2E-45 T 29-03-2018 IPR006433 Prohead protease CSW12_RS05165 18c03efcdea12a8fdd7c99eeaa7d087d 202 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 20 161 5.8E-21 T 29-03-2018 IPR006433 Prohead protease CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 SUPERFAMILY SSF51735 112 272 2.59E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 Gene3D G3DSA:3.90.180.10 1 319 2.5E-64 T 29-03-2018 CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 SUPERFAMILY SSF50129 1 144 1.52E-34 T 29-03-2018 IPR011032 GroES-like CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 Pfam PF00107 Zinc-binding dehydrogenase 151 259 5.5E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 SMART SM00829 10 319 2.7E-21 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 5.8E-10 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS10515 bb108b8a27b46d8c003414b2dd36f7b5 321 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CSW12_RS23880 850f9e14121ebf467f5d687cadd58d1e 209 Pfam PF13630 SdpI/YhfL protein family 131 194 2.8E-16 T 29-03-2018 IPR025962 SdpI/YhfL protein family CSW12_RS23880 850f9e14121ebf467f5d687cadd58d1e 209 PIRSF PIRSF038959 1 209 1.1E-31 T 29-03-2018 IPR026272 Immunity protein SdpI CSW12_RS23880 850f9e14121ebf467f5d687cadd58d1e 209 Pfam PF07853 Protein of unknown function (DUF1648) 11 48 8.9E-12 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CSW12_RS10590 a42387045b0d0d2ba7443e5c64637da6 441 Pfam PF03600 Citrate transporter 26 382 6.4E-51 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CSW12_RS10590 a42387045b0d0d2ba7443e5c64637da6 441 PRINTS PR00758 Arsenical pump membrane protein signature 227 252 1.3E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS10590 a42387045b0d0d2ba7443e5c64637da6 441 PRINTS PR00758 Arsenical pump membrane protein signature 378 403 1.3E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS10590 a42387045b0d0d2ba7443e5c64637da6 441 PRINTS PR00758 Arsenical pump membrane protein signature 286 310 1.3E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS10590 a42387045b0d0d2ba7443e5c64637da6 441 PRINTS PR00758 Arsenical pump membrane protein signature 110 134 1.3E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS10590 a42387045b0d0d2ba7443e5c64637da6 441 PRINTS PR00758 Arsenical pump membrane protein signature 411 435 1.3E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS24300 2b750a3d522caeebbb0fd76d46effb0e 168 Pfam PF01037 Lrp/AsnC ligand binding domain 73 146 5.2E-13 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CSW12_RS24300 2b750a3d522caeebbb0fd76d46effb0e 168 SMART SM00344 7 118 0.0071 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CSW12_RS24300 2b750a3d522caeebbb0fd76d46effb0e 168 Gene3D G3DSA:1.10.10.10 2 55 1.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24300 2b750a3d522caeebbb0fd76d46effb0e 168 SUPERFAMILY SSF46785 7 62 2.3E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24300 2b750a3d522caeebbb0fd76d46effb0e 168 SUPERFAMILY SSF54909 68 149 2.01E-16 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS24300 2b750a3d522caeebbb0fd76d46effb0e 168 Gene3D G3DSA:3.30.70.920 57 155 2.9E-23 T 29-03-2018 CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 Gene3D G3DSA:3.30.70.270 109 366 1.4E-39 T 29-03-2018 CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 Gene3D G3DSA:3.40.1800.10 530 605 4.6E-5 T 29-03-2018 CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 Pfam PF01348 Type II intron maturase 410 488 5.0E-11 T 29-03-2018 IPR024937 Domain X GO:0006397 CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 SUPERFAMILY SSF56672 42 232 2.92E-46 T 29-03-2018 CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 SUPERFAMILY SSF56672 303 369 2.92E-46 T 29-03-2018 CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 88 234 1.6E-33 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS29270 e2c554dce465dc3e58061a1af7596111 606 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 301 365 7.1E-7 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS24780 62bfb06676a514eb2a46fe502cfb392c 215 SUPERFAMILY SSF48317 15 212 3.92E-6 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS24780 62bfb06676a514eb2a46fe502cfb392c 215 Pfam PF14378 PAP2 superfamily 51 192 3.2E-10 T 29-03-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CSW12_RS24780 62bfb06676a514eb2a46fe502cfb392c 215 Gene3D G3DSA:1.20.144.10 21 210 8.9E-7 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS06735 8ea5624c5dd50381e6e34eca85d81e8e 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 5.8E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS06735 8ea5624c5dd50381e6e34eca85d81e8e 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 298 317 5.8E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS06735 8ea5624c5dd50381e6e34eca85d81e8e 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 5.8E-11 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS06735 8ea5624c5dd50381e6e34eca85d81e8e 452 Pfam PF00209 Sodium:neurotransmitter symporter family 150 446 9.1E-29 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS06735 8ea5624c5dd50381e6e34eca85d81e8e 452 Pfam PF00209 Sodium:neurotransmitter symporter family 6 123 2.7E-24 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS06735 8ea5624c5dd50381e6e34eca85d81e8e 452 SUPERFAMILY SSF161070 7 445 1.7E-129 T 29-03-2018 CSW12_RS26875 b8e10e57c95e7f4a887d79163be17fc0 399 Gene3D G3DSA:1.20.1250.20 196 399 1.6E-29 T 29-03-2018 CSW12_RS26875 b8e10e57c95e7f4a887d79163be17fc0 399 SUPERFAMILY SSF103473 9 397 1.44E-87 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS26875 b8e10e57c95e7f4a887d79163be17fc0 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 269 284 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS26875 b8e10e57c95e7f4a887d79163be17fc0 399 Pfam PF07690 Major Facilitator Superfamily 21 261 2.9E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS26875 b8e10e57c95e7f4a887d79163be17fc0 399 ProSitePatterns PS00217 Sugar transport proteins signature 2. 108 133 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS26875 b8e10e57c95e7f4a887d79163be17fc0 399 Gene3D G3DSA:1.20.1250.20 1 195 1.2E-41 T 29-03-2018 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Gene3D G3DSA:2.60.40.1180 774 848 1.1E-19 T 29-03-2018 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 SUPERFAMILY SSF51445 335 759 7.89E-127 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Gene3D G3DSA:2.60.40.1110 19 130 8.6E-26 T 29-03-2018 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Pfam PF00128 Alpha amylase, catalytic domain 516 713 2.0E-5 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Pfam PF00128 Alpha amylase, catalytic domain 389 485 2.0E-9 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 SUPERFAMILY SSF51011 778 845 2.01E-5 T 29-03-2018 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Gene3D G3DSA:2.60.40.1130 139 222 6.6E-16 T 29-03-2018 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 238 316 4.3E-14 T 29-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Pfam PF03714 Bacterial pullanase-associated domain 41 131 4.7E-22 T 29-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 PIRSF PIRSF000463 126 549 9.1E-32 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 PIRSF PIRSF000463 642 836 0.89 T 29-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 SUPERFAMILY SSF49452 39 133 1.34E-26 T 29-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 227 825 4.5E-279 T 29-03-2018 IPR011840 Pullulanase, type I CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Gene3D G3DSA:3.20.20.80 336 761 1.5E-94 T 29-03-2018 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 SUPERFAMILY SSF81296 231 336 1.46E-21 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 SMART SM00642 353 752 8.5E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS14035 25b8c7cbcdc52bf198e3c38bb49b3698 852 Gene3D G3DSA:2.60.40.10 235 335 3.3E-27 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS00870 4b0891510da21fe1b5d4ec42f0392fef 437 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 9 380 6.1E-59 T 29-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CSW12_RS00870 4b0891510da21fe1b5d4ec42f0392fef 437 SUPERFAMILY SSF53649 7 420 8.67E-79 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS00870 4b0891510da21fe1b5d4ec42f0392fef 437 Gene3D G3DSA:3.40.720.10 2 436 1.0E-41 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS26620 a0c3aa98b12bf2c59b7b72ab93a06f99 345 Pfam PF13303 Phosphotransferase system, EIIC 28 331 4.4E-59 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 Pfam PF00270 DEAD/DEAH box helicase 26 190 1.1E-50 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 29-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 SUPERFAMILY SSF52540 71 356 2.46E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 SMART SM00490 254 335 1.3E-34 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 Gene3D G3DSA:3.40.50.300 219 518 1.7E-48 T 29-03-2018 CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 Pfam PF00271 Helicase conserved C-terminal domain 227 335 5.6E-29 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 524 47.453 T 29-03-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 Gene3D G3DSA:3.40.50.300 9 218 1.5E-59 T 29-03-2018 CSW12_RS28670 fe5101cd99b74d08adf903a00d48cdd2 529 SMART SM00487 21 218 6.1E-66 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS29940 51eb1bb026487461171f32e7eecc6b64 595 Gene3D G3DSA:3.40.50.1110 398 595 2.9E-24 T 29-03-2018 CSW12_RS29940 51eb1bb026487461171f32e7eecc6b64 595 Pfam PF01757 Acyltransferase family 14 342 1.3E-24 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS29940 51eb1bb026487461171f32e7eecc6b64 595 SUPERFAMILY SSF52266 432 593 4.73E-16 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS16285 64f0e5d806384a4b2b1c0db586d5ec97 478 Gene3D G3DSA:1.10.4100.10 389 478 1.1E-12 T 29-03-2018 CSW12_RS16285 64f0e5d806384a4b2b1c0db586d5ec97 478 Gene3D G3DSA:1.10.4100.10 1 326 1.8E-96 T 29-03-2018 CSW12_RS16285 64f0e5d806384a4b2b1c0db586d5ec97 478 SUPERFAMILY SSF103378 11 476 3.01E-160 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CSW12_RS16285 64f0e5d806384a4b2b1c0db586d5ec97 478 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 11 478 7.4E-284 T 29-03-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 CSW12_RS16285 64f0e5d806384a4b2b1c0db586d5ec97 478 Pfam PF03972 MmgE/PrpD family 15 461 9.3E-153 T 29-03-2018 IPR005656 MmgE/PrpD GO:0016829 CSW12_RS10555 1b2cc6f138564d493111a0012de873b4 328 Pfam PF13170 Protein of unknown function (DUF4003) 15 308 2.1E-102 T 29-03-2018 IPR025062 Protein of unknown function DUF4003 CSW12_RS19130 98d867a52ff329081475236591f3a352 341 Pfam PF13343 Bacterial extracellular solute-binding protein 89 327 2.4E-40 T 29-03-2018 CSW12_RS19130 98d867a52ff329081475236591f3a352 341 PIRSF PIRSF002825 1 340 9.1E-62 T 29-03-2018 IPR026045 Ferric binding protein CSW12_RS19130 98d867a52ff329081475236591f3a352 341 Gene3D G3DSA:3.40.190.10 34 151 3.9E-12 T 29-03-2018 CSW12_RS19130 98d867a52ff329081475236591f3a352 341 Gene3D G3DSA:3.40.190.10 152 292 1.1E-35 T 29-03-2018 CSW12_RS19130 98d867a52ff329081475236591f3a352 341 SUPERFAMILY SSF53850 42 336 4.91E-69 T 29-03-2018 CSW12_RS16085 e00c9747c9fd07cf9826bc6ee5535bf5 428 Gene3D G3DSA:1.20.1250.20 221 420 3.7E-14 T 29-03-2018 CSW12_RS16085 e00c9747c9fd07cf9826bc6ee5535bf5 428 Pfam PF07690 Major Facilitator Superfamily 25 368 2.4E-20 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS16085 e00c9747c9fd07cf9826bc6ee5535bf5 428 Gene3D G3DSA:1.20.1250.20 6 216 4.4E-24 T 29-03-2018 CSW12_RS16085 e00c9747c9fd07cf9826bc6ee5535bf5 428 SUPERFAMILY SSF103473 17 419 4.97E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 Gene3D G3DSA:1.10.10.10 1 52 3.6E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 4.0E-18 T 29-03-2018 CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 Pfam PF01037 Lrp/AsnC ligand binding domain 70 136 4.4E-12 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 SMART SM00344 3 109 7.6E-38 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 SUPERFAMILY SSF54909 67 137 5.36E-15 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 Gene3D G3DSA:3.30.70.920 53 142 3.3E-17 T 29-03-2018 CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 SUPERFAMILY SSF46785 2 62 8.8E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.5E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.5E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS06365 d10baf9bf0ce0f9ff41adcd3344801f6 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.5E-16 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS09345 297a9687c09626043dcd6de851f1269b 73 Hamap MF_00363 UPF0154 protein . 2 72 21.922 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CSW12_RS09345 297a9687c09626043dcd6de851f1269b 73 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 41 1.0E-7 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CSW12_RS09345 297a9687c09626043dcd6de851f1269b 73 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 3.1E-30 T 29-03-2018 IPR005359 Protein with unknown function UPF0154 CSW12_RS11470 2b6b7abe31715db6c9f570173cbe26a1 399 Gene3D G3DSA:1.20.1250.20 2 199 4.8E-37 T 29-03-2018 CSW12_RS11470 2b6b7abe31715db6c9f570173cbe26a1 399 Pfam PF07690 Major Facilitator Superfamily 15 347 5.7E-59 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS11470 2b6b7abe31715db6c9f570173cbe26a1 399 SUPERFAMILY SSF103473 1 390 5.89E-70 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11470 2b6b7abe31715db6c9f570173cbe26a1 399 Gene3D G3DSA:1.20.1250.20 200 387 1.7E-29 T 29-03-2018 CSW12_RS19860 ddcbeb077a3a28dfa5df0aa0b33254ad 235 SUPERFAMILY SSF158499 130 195 1.83E-19 T 29-03-2018 IPR006343 DnaD domain CSW12_RS19860 ddcbeb077a3a28dfa5df0aa0b33254ad 235 Gene3D G3DSA:1.10.10.630 128 201 8.0E-25 T 29-03-2018 IPR034829 DnaD-like domain CSW12_RS19860 ddcbeb077a3a28dfa5df0aa0b33254ad 235 Gene3D G3DSA:1.10.10.10 16 127 1.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19860 ddcbeb077a3a28dfa5df0aa0b33254ad 235 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 200 1.2E-25 T 29-03-2018 IPR006343 DnaD domain CSW12_RS19860 ddcbeb077a3a28dfa5df0aa0b33254ad 235 Pfam PF07261 Replication initiation and membrane attachment 131 201 6.1E-26 T 29-03-2018 IPR006343 DnaD domain CSW12_RS19860 ddcbeb077a3a28dfa5df0aa0b33254ad 235 SUPERFAMILY SSF46785 29 86 6.2E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 Gene3D G3DSA:3.30.230.10 6 162 3.3E-52 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 Pfam PF00288 GHMP kinases N terminal domain 90 147 2.3E-13 T 29-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 SUPERFAMILY SSF55060 164 284 2.16E-32 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 PIRSF PIRSF010376 5 290 1.4E-99 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 SUPERFAMILY SSF54211 6 160 1.52E-48 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 Pfam PF08544 GHMP kinases C terminal 204 272 1.9E-7 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 282 36.28 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 Gene3D G3DSA:3.30.70.890 164 290 8.1E-28 T 29-03-2018 IPR013750 GHMP kinase, C-terminal domain CSW12_RS27570 2c1929e19f8088c666386db3cb7829b3 292 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 288 7.3E-111 T 29-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CSW12_RS28540 cda8c7482e11b088a9697d6c9fef8f18 177 Gene3D G3DSA:1.10.530.10 31 172 1.7E-11 T 29-03-2018 CSW12_RS28540 cda8c7482e11b088a9697d6c9fef8f18 177 SUPERFAMILY SSF53955 43 141 5.89E-12 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS28540 cda8c7482e11b088a9697d6c9fef8f18 177 Pfam PF01464 Transglycosylase SLT domain 46 126 1.3E-8 T 29-03-2018 IPR008258 Transglycosylase SLT domain 1 CSW12_RS18210 d34d66b7a79254896fde8be3f854027d 405 Pfam PF13458 Periplasmic binding protein 39 377 1.7E-70 T 29-03-2018 IPR028081 Leucine-binding protein domain CSW12_RS18210 d34d66b7a79254896fde8be3f854027d 405 Gene3D G3DSA:3.40.50.2300 37 222 3.2E-36 T 29-03-2018 CSW12_RS18210 d34d66b7a79254896fde8be3f854027d 405 SUPERFAMILY SSF53822 39 385 1.74E-80 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS18210 d34d66b7a79254896fde8be3f854027d 405 Gene3D G3DSA:3.40.50.2300 223 369 5.2E-20 T 29-03-2018 CSW12_RS19215 d0a8b9f90f9fc9bdcefe78086cb7ad69 436 Gene3D G3DSA:3.40.50.300 239 435 6.7E-25 T 29-03-2018 CSW12_RS19215 d0a8b9f90f9fc9bdcefe78086cb7ad69 436 SUPERFAMILY SSF52540 239 426 4.02E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19215 d0a8b9f90f9fc9bdcefe78086cb7ad69 436 SMART SM00382 240 378 2.1E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS19215 d0a8b9f90f9fc9bdcefe78086cb7ad69 436 SMART SM00962 241 434 1.4E-39 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS19215 d0a8b9f90f9fc9bdcefe78086cb7ad69 436 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 10 330 8.8E-52 T 29-03-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CSW12_RS19215 d0a8b9f90f9fc9bdcefe78086cb7ad69 436 Pfam PF00448 SRP54-type protein, GTPase domain 243 433 9.8E-40 T 29-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CSW12_RS01915 8c73a121ef28aac3371ceb48a30f03c2 476 ProSitePatterns PS00218 Amino acid permeases signature. 42 73 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS01915 8c73a121ef28aac3371ceb48a30f03c2 476 Pfam PF00324 Amino acid permease 17 456 6.4E-120 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS01915 8c73a121ef28aac3371ceb48a30f03c2 476 PIRSF PIRSF006060 1 475 5.0E-85 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 SUPERFAMILY SSF53697 5 247 2.16E-66 T 29-03-2018 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 Pfam PF13580 SIS domain 36 163 2.6E-8 T 29-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 Gene3D G3DSA:1.10.8.10 242 267 6.6E-8 T 29-03-2018 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 Gene3D G3DSA:1.10.8.10 268 294 0.017 T 29-03-2018 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 184 201 - T 29-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 5 294 5.1E-114 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 Gene3D G3DSA:3.40.50.10490 9 241 3.2E-52 T 29-03-2018 CSW12_RS03455 e15880bc3f0c137c7e76a108eace0d3c 294 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 1 294 41.874 T 29-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Gene3D G3DSA:3.90.400.10 104 167 2.9E-32 T 29-03-2018 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 SMART SM00642 13 415 2.4E-162 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 548 7.4E-9 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Gene3D G3DSA:3.20.20.80 340 476 2.2E-23 T 29-03-2018 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 SUPERFAMILY SSF51445 4 473 3.81E-156 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 SUPERFAMILY SSF51011 476 553 1.39E-17 T 29-03-2018 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Pfam PF00128 Alpha amylase, catalytic domain 28 373 1.8E-116 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Gene3D G3DSA:2.60.40.1180 477 554 5.0E-21 T 29-03-2018 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Gene3D G3DSA:3.20.20.470 1 103 6.5E-36 T 29-03-2018 CSW12_RS00740 5ec4981e24a0239aa3d63f103c01ef24 554 Gene3D G3DSA:3.20.20.470 168 339 2.1E-37 T 29-03-2018 CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 29-03-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 Pfam PF00381 PTS HPr component phosphorylation site 3 81 1.9E-29 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.1E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.1E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.1E-21 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 Gene3D G3DSA:3.30.1340.10 1 82 4.0E-33 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 SUPERFAMILY SSF55594 3 81 7.2E-28 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS25455 4c3f84f6b35679ee84574a79ac5b9e09 82 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 81 6.3E-30 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS08020 13ba88b3852dec8fcd659789f640113a 311 Pfam PF02628 Cytochrome oxidase assembly protein 7 286 2.1E-39 T 29-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CSW12_RS08020 13ba88b3852dec8fcd659789f640113a 311 Hamap MF_01664 Heme A synthase [ctaA]. 1 301 30.891 T 29-03-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 CSW12_RS02990 9ad234f48b6988a652377d1e1136cae0 339 TIGRFAM TIGR02356 adenyl_thiF: thiazole biosynthesis adenylyltransferase ThiF 4 206 7.3E-84 T 29-03-2018 IPR012731 Thiazole biosynthesis adenylyltransferase ThiF KEGG: 00730+2.7.7.73|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CSW12_RS02990 9ad234f48b6988a652377d1e1136cae0 339 SUPERFAMILY SSF69572 2 330 3.4E-87 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS02990 9ad234f48b6988a652377d1e1136cae0 339 Gene3D G3DSA:3.40.50.720 1 245 3.4E-65 T 29-03-2018 CSW12_RS02990 9ad234f48b6988a652377d1e1136cae0 339 Pfam PF00899 ThiF family 5 241 2.3E-60 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 2 83 1.3E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 321 420 2.5E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 84 188 1.5E-17 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF13176 Tetratricopeptide repeat 174 201 1.0E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF13176 Tetratricopeptide repeat 140 163 0.0084 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SUPERFAMILY SSF48452 34 199 1.42E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 248 320 2.0E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Gene3D G3DSA:1.25.40.10 189 247 2.5E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF13429 Tetratricopeptide repeat 219 400 4.9E-8 T 29-03-2018 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 339 372 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 170 203 2.5 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 373 406 47.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 271 304 4.1E-4 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 237 270 14.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SMART SM00028 134 167 41.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 Pfam PF14559 Tetratricopeptide repeat 49 104 4.1E-6 T 29-03-2018 CSW12_RS20005 1f7c5e1dd3e47653f6fb13407dcb85a8 420 SUPERFAMILY SSF48452 176 408 4.55E-28 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 SUPERFAMILY SSF89260 502 611 1.57E-32 T 29-03-2018 CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 SUPERFAMILY SSF52743 179 467 2.09E-36 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 PRINTS PR00723 Subtilisin serine protease family (S8) signature 233 246 1.6E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 PRINTS PR00723 Subtilisin serine protease family (S8) signature 420 436 1.6E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 PRINTS PR00723 Subtilisin serine protease family (S8) signature 199 218 1.6E-8 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 Gene3D G3DSA:3.40.50.200 133 497 6.1E-31 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 421 431 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 Pfam PF00082 Subtilase family 201 467 6.9E-18 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 533 598 5.7E-6 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial CSW12_RS08975 4c7e34325f048040f2a08152c481fb03 612 Gene3D G3DSA:2.60.120.380 498 612 8.1E-21 T 29-03-2018 CSW12_RS29810 6954d8192785f5cd6611b6e9899a4e49 393 SUPERFAMILY SSF52540 136 334 2.03E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS29810 6954d8192785f5cd6611b6e9899a4e49 393 Pfam PF01580 FtsK/SpoIIIE family 127 236 1.9E-18 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS29810 6954d8192785f5cd6611b6e9899a4e49 393 Gene3D G3DSA:3.40.50.300 15 390 7.2E-17 T 29-03-2018 CSW12_RS15130 45175b99148abe85151879f01c682bff 303 SUPERFAMILY SSF50022 13 108 2.88E-29 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS15130 45175b99148abe85151879f01c682bff 303 Gene3D G3DSA:2.102.10.10 5 92 1.8E-22 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS15130 45175b99148abe85151879f01c682bff 303 Pfam PF00355 Rieske [2Fe-2S] domain 12 84 2.1E-19 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS15130 45175b99148abe85151879f01c682bff 303 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 41 63 - T 29-03-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CSW12_RS15130 45175b99148abe85151879f01c682bff 303 Gene3D G3DSA:3.90.380.10 93 298 1.7E-27 T 29-03-2018 CSW12_RS15130 45175b99148abe85151879f01c682bff 303 SUPERFAMILY SSF55961 100 295 9.06E-23 T 29-03-2018 CSW12_RS17505 5f98d494919a3835ef36186b53fd4764 378 Gene3D G3DSA:1.20.1250.20 1 184 1.3E-31 T 29-03-2018 CSW12_RS17505 5f98d494919a3835ef36186b53fd4764 378 Gene3D G3DSA:1.20.1250.20 191 378 6.0E-22 T 29-03-2018 CSW12_RS17505 5f98d494919a3835ef36186b53fd4764 378 Pfam PF07690 Major Facilitator Superfamily 10 314 1.3E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS17505 5f98d494919a3835ef36186b53fd4764 378 SUPERFAMILY SSF103473 3 376 5.23E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 SUPERFAMILY SSF54106 97 140 1.44E-11 T 29-03-2018 IPR018392 LysM domain CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 Gene3D G3DSA:3.10.350.10 95 142 2.3E-14 T 29-03-2018 CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 Gene3D G3DSA:3.10.350.10 24 92 1.4E-14 T 29-03-2018 CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 Pfam PF01476 LysM domain 99 140 1.8E-12 T 29-03-2018 IPR018392 LysM domain CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 Pfam PF01476 LysM domain 32 74 1.3E-12 T 29-03-2018 IPR018392 LysM domain CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 Pfam PF07486 Cell Wall Hydrolase 162 263 8.1E-23 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 SUPERFAMILY SSF54106 30 74 1.06E-10 T 29-03-2018 IPR018392 LysM domain CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 SMART SM00257 31 74 4.6E-12 T 29-03-2018 IPR018392 LysM domain CSW12_RS08970 79fb1854e1f8d6e29d5e3ee145017335 265 SMART SM00257 98 141 7.6E-13 T 29-03-2018 IPR018392 LysM domain CSW12_RS01990 b87a34472ec5e151adc59b216579ef67 301 SUPERFAMILY SSF161098 90 284 2.09E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01990 b87a34472ec5e151adc59b216579ef67 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 292 4.4E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01990 b87a34472ec5e151adc59b216579ef67 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 71 2.0E-7 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CSW12_RS01990 b87a34472ec5e151adc59b216579ef67 301 Gene3D G3DSA:1.10.3720.10 24 288 3.9E-37 T 29-03-2018 CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 261 1.3E-69 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 Gene3D G3DSA:3.40.50.1000 1 147 3.0E-23 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 29-03-2018 CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 SUPERFAMILY SSF56784 1 267 1.27E-76 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 261 2.5E-70 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 Gene3D G3DSA:3.40.50.1000 148 272 1.1E-21 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS26765 58bed1bc1ff0be587891500a0f05997d 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 3.5E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 Pfam PF01312 FlhB HrpN YscU SpaS Family 5 339 2.3E-111 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 Gene3D G3DSA:3.40.1690.10 211 345 4.3E-46 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 295 316 5.9E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 221 238 5.9E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 265 280 5.9E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 7 29 5.9E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 201 219 5.9E-38 T 29-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CSW12_RS19225 5e33c0eb13224327bcbc10e602fd787d 348 SUPERFAMILY SSF160544 237 344 1.1E-33 T 29-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CSW12_RS02670 3f5f75607170e77a841dba71f1c01a6a 430 Pfam PF00860 Permease family 13 393 6.9E-45 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS02670 3f5f75607170e77a841dba71f1c01a6a 430 PIRSF PIRSF005353 1 430 4.1E-146 T 29-03-2018 IPR026033 Purine permease PbuG-like CSW12_RS14070 0d858a8ca60826616b1c70fc82e323f7 225 Pfam PF00005 ABC transporter 24 170 4.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14070 0d858a8ca60826616b1c70fc82e323f7 225 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS14070 0d858a8ca60826616b1c70fc82e323f7 225 Gene3D G3DSA:3.40.50.300 1 224 3.5E-63 T 29-03-2018 CSW12_RS14070 0d858a8ca60826616b1c70fc82e323f7 225 SMART SM00382 33 219 3.6E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14070 0d858a8ca60826616b1c70fc82e323f7 225 SUPERFAMILY SSF52540 3 221 1.46E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18295 bb666de9f222c69b60a9981f98a3926a 458 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 20 427 3.0E-157 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS18295 bb666de9f222c69b60a9981f98a3926a 458 Pfam PF05525 Branched-chain amino acid transport protein 16 439 1.6E-162 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS02685 4d0f55e071716e6e1fc87da9f9811f09 145 SUPERFAMILY SSF55729 14 133 1.8E-17 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS02685 4d0f55e071716e6e1fc87da9f9811f09 145 Gene3D G3DSA:3.40.630.30 1 144 1.3E-15 T 29-03-2018 CSW12_RS02685 4d0f55e071716e6e1fc87da9f9811f09 145 Pfam PF00583 Acetyltransferase (GNAT) family 35 123 1.8E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 ProSitePatterns PS00211 ABC transporters family signature. 438 452 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 Gene3D G3DSA:3.40.50.300 1 269 5.3E-50 T 29-03-2018 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 Gene3D G3DSA:3.40.50.300 284 514 2.0E-42 T 29-03-2018 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 SUPERFAMILY SSF52540 304 512 2.58E-39 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 Pfam PF00005 ABC transporter 338 466 4.6E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 Pfam PF00005 ABC transporter 20 188 8.8E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 SUPERFAMILY SSF52540 4 242 3.04E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 SMART SM00382 28 233 5.1E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 SMART SM00382 345 511 2.8E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25210 12e2a88297d6fb1850dab1c28a482de7 515 Pfam PF12848 ABC transporter 228 311 1.6E-22 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS19625 6dd6108f820233120b926de7b896954d 521 SUPERFAMILY SSF51126 1 287 3.14E-20 T 29-03-2018 IPR011050 Pectin lyase fold/virulence factor CSW12_RS19625 6dd6108f820233120b926de7b896954d 521 Gene3D G3DSA:2.160.20.10 7 480 5.4E-19 T 29-03-2018 IPR012334 Pectin lyase fold CSW12_RS01260 adf3519245bc9c09103204a3fc841559 337 SUPERFAMILY SSF52540 35 252 3.2E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01260 adf3519245bc9c09103204a3fc841559 337 Gene3D G3DSA:3.40.50.300 1 295 5.9E-59 T 29-03-2018 CSW12_RS01260 adf3519245bc9c09103204a3fc841559 337 Pfam PF00005 ABC transporter 42 185 2.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS01260 adf3519245bc9c09103204a3fc841559 337 SMART SM00382 50 234 8.1E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25365 a60def496393220e17bb0c8107adfcb2 342 SUPERFAMILY SSF46785 19 81 7.35E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25365 a60def496393220e17bb0c8107adfcb2 342 Pfam PF04198 Putative sugar-binding domain 90 336 2.9E-69 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CSW12_RS25365 a60def496393220e17bb0c8107adfcb2 342 Gene3D G3DSA:3.40.50.1360 88 340 7.5E-37 T 29-03-2018 CSW12_RS25365 a60def496393220e17bb0c8107adfcb2 342 SUPERFAMILY SSF100950 90 336 7.78E-69 T 29-03-2018 CSW12_RS25365 a60def496393220e17bb0c8107adfcb2 342 Gene3D G3DSA:1.10.10.10 17 87 9.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22305 f01816b0b408d40dbe4cfa0455db5c9a 64 Pfam PF09962 Uncharacterized conserved protein (DUF2196) 2 62 3.2E-34 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 CSW12_RS22305 f01816b0b408d40dbe4cfa0455db5c9a 64 TIGRFAM TIGR03833 TIGR03833: conserved hypothetical protein 2 63 7.5E-37 T 29-03-2018 IPR019240 Protein of unknown function DUF2196 CSW12_RS11500 1cb68b0055d11d11140fc25b695f7fe7 411 SMART SM00854 76 323 8.7E-86 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CSW12_RS11500 1cb68b0055d11d11140fc25b695f7fe7 411 SUPERFAMILY SSF56300 76 341 6.59E-42 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS11500 1cb68b0055d11d11140fc25b695f7fe7 411 Gene3D G3DSA:3.60.21.10 67 370 5.3E-52 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS11500 1cb68b0055d11d11140fc25b695f7fe7 411 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 77 323 3.5E-70 T 29-03-2018 IPR019079 Capsule synthesis protein, CapA CSW12_RS19615 53e06b547c3a571d9ba7274b8554b464 286 Pfam PF13673 Acetyltransferase (GNAT) domain 33 123 4.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS19615 53e06b547c3a571d9ba7274b8554b464 286 Gene3D G3DSA:3.40.630.30 3 164 6.9E-16 T 29-03-2018 CSW12_RS19615 53e06b547c3a571d9ba7274b8554b464 286 SUPERFAMILY SSF55729 6 265 9.94E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06965 1200395ce11a6d43bf6ee972545ae241 385 Pfam PF01578 Cytochrome C assembly protein 255 382 1.7E-26 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CSW12_RS06965 1200395ce11a6d43bf6ee972545ae241 385 Pfam PF01578 Cytochrome C assembly protein 77 173 1.2E-8 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CSW12_RS06965 1200395ce11a6d43bf6ee972545ae241 385 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 42 385 5.2E-77 T 29-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CSW12_RS23445 1c57337ded49910bae1a4620982af119 190 SUPERFAMILY SSF53335 12 163 2.57E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS23445 1c57337ded49910bae1a4620982af119 190 Pfam PF06962 Putative rRNA methylase 48 188 1.1E-49 T 29-03-2018 IPR010719 Putative rRNA methylase CSW12_RS23445 1c57337ded49910bae1a4620982af119 190 Gene3D G3DSA:3.40.50.150 3 190 2.4E-19 T 29-03-2018 CSW12_RS11535 6bc421b1b06fcb5483bd991eaab0f7c6 258 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 174 235 1.7E-16 T 29-03-2018 IPR006343 DnaD domain CSW12_RS11535 6bc421b1b06fcb5483bd991eaab0f7c6 258 Pfam PF07261 Replication initiation and membrane attachment 174 235 2.3E-11 T 29-03-2018 IPR006343 DnaD domain CSW12_RS11535 6bc421b1b06fcb5483bd991eaab0f7c6 258 SUPERFAMILY SSF158499 173 235 4.84E-15 T 29-03-2018 IPR006343 DnaD domain CSW12_RS11535 6bc421b1b06fcb5483bd991eaab0f7c6 258 Gene3D G3DSA:1.10.10.630 168 238 1.6E-16 T 29-03-2018 IPR034829 DnaD-like domain CSW12_RS05390 1b1937d7c715ddf9a60518ff1b6bea70 244 SUPERFAMILY SSF53474 15 240 2.12E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS05390 1b1937d7c715ddf9a60518ff1b6bea70 244 Gene3D G3DSA:3.40.50.1820 12 241 1.0E-13 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS04410 085bced77a01fc4f3f16b6a7ec8160ef 314 Gene3D G3DSA:3.10.180.10 155 314 1.3E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS04410 085bced77a01fc4f3f16b6a7ec8160ef 314 Gene3D G3DSA:3.10.180.10 1 154 4.6E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS04410 085bced77a01fc4f3f16b6a7ec8160ef 314 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 271 1.6E-19 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS04410 085bced77a01fc4f3f16b6a7ec8160ef 314 SUPERFAMILY SSF54593 2 299 1.93E-47 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS14125 420efa12aaec482f1ecd0d3ec613df5f 371 SUPERFAMILY SSF54373 224 311 4.97E-17 T 29-03-2018 CSW12_RS14125 420efa12aaec482f1ecd0d3ec613df5f 371 Pfam PF01266 FAD dependent oxidoreductase 4 351 2.7E-55 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS14125 420efa12aaec482f1ecd0d3ec613df5f 371 Gene3D G3DSA:3.50.50.60 2 367 4.8E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS14125 420efa12aaec482f1ecd0d3ec613df5f 371 SUPERFAMILY SSF51905 312 366 4.79E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS14125 420efa12aaec482f1ecd0d3ec613df5f 371 SUPERFAMILY SSF51905 2 221 4.79E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS06140 8d7b963a1135ecd406449dc1b2015cf1 113 Pfam PF13045 Protein of unknown function (DUF3905) 11 93 1.7E-47 T 29-03-2018 IPR024999 Protein of unknown function DUF3905 CSW12_RS02070 fce8c82099aa7fc0ed0fb61776ab3e66 272 Pfam PF10552 ORF6C domain 147 259 2.3E-31 T 29-03-2018 IPR018878 ORF6C domain CSW12_RS02070 fce8c82099aa7fc0ed0fb61776ab3e66 272 Pfam PF10543 ORF6N domain 33 113 4.6E-9 T 29-03-2018 IPR018873 KilA-N, DNA-binding domain CSW12_RS19370 2c873168417a6d8456acbdf0dc5d7164 122 Gene3D G3DSA:1.20.120.340 1 121 1.2E-16 T 29-03-2018 CSW12_RS19370 2c873168417a6d8456acbdf0dc5d7164 122 Pfam PF02561 Flagellar protein FliS 5 116 9.8E-19 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CSW12_RS19370 2c873168417a6d8456acbdf0dc5d7164 122 SUPERFAMILY SSF101116 2 120 1.24E-22 T 29-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CSW12_RS16735 3acaf23877cbb88c757febdf2140134e 1301 Pfam PF07693 KAP family P-loop domain 25 380 5.1E-38 T 29-03-2018 IPR011646 KAP family P-loop domain CSW12_RS16735 3acaf23877cbb88c757febdf2140134e 1301 Gene3D G3DSA:3.40.50.300 3 298 2.4E-11 T 29-03-2018 CSW12_RS16735 3acaf23877cbb88c757febdf2140134e 1301 SUPERFAMILY SSF52540 15 93 7.87E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16735 3acaf23877cbb88c757febdf2140134e 1301 SUPERFAMILY SSF52540 220 294 7.87E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16735 3acaf23877cbb88c757febdf2140134e 1301 Gene3D G3DSA:1.10.287.110 861 946 0.068 T 29-03-2018 IPR001623 DnaJ domain CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 429 3.4E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 SMART SM00387 321 433 9.1E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 430 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 410 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 1.1E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 SUPERFAMILY SSF55874 283 429 1.01E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15490 d7b4d5e659c19d4d22cc01f001e42639 438 Gene3D G3DSA:3.30.565.10 180 431 7.5E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS00390 e48624507fa69f0a0933bac67fd4fa80 250 SMART SM00287 191 249 0.0017 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS00390 e48624507fa69f0a0933bac67fd4fa80 250 Gene3D G3DSA:2.30.30.410 170 250 2.9E-11 T 29-03-2018 CSW12_RS00390 e48624507fa69f0a0933bac67fd4fa80 250 SUPERFAMILY SSF53187 2 168 2.92E-36 T 29-03-2018 CSW12_RS00390 e48624507fa69f0a0933bac67fd4fa80 250 SMART SM00646 65 167 1.0E-23 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS00390 e48624507fa69f0a0933bac67fd4fa80 250 Gene3D G3DSA:3.40.630.40 2 169 7.7E-33 T 29-03-2018 CSW12_RS00390 e48624507fa69f0a0933bac67fd4fa80 250 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 8 165 1.1E-26 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS25370 afb918025e000282d784868a4f0f8472 81 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 60 2.3E-18 T 29-03-2018 IPR008554 Glutaredoxin-like CSW12_RS25370 afb918025e000282d784868a4f0f8472 81 SUPERFAMILY SSF52833 1 78 4.5E-21 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS25370 afb918025e000282d784868a4f0f8472 81 Gene3D G3DSA:3.40.30.10 1 77 2.7E-13 T 29-03-2018 CSW12_RS10940 04f6e8263e4f0424f755b8ac98de8a3c 111 SMART SM00914 65 100 4.6E-8 T 29-03-2018 IPR014957 IDEAL domain CSW12_RS10940 04f6e8263e4f0424f755b8ac98de8a3c 111 Pfam PF08858 IDEAL domain 74 100 4.3E-7 T 29-03-2018 IPR014957 IDEAL domain CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 SUPERFAMILY SSF46785 29 122 4.89E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 SMART SM00418 41 119 8.8E-31 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 Gene3D G3DSA:1.10.10.10 7 125 8.8E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 64 82 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 Pfam PF01022 Bacterial regulatory protein, arsR family 48 93 1.1E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.4E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 1.4E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 73 1.4E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01690 b88d0e10b9a11fe97b92fbe4f6082af1 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 1.4E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS27825 ebf632a00a29e392c4389a0c2096edff 182 Pfam PF02151 UvrB/uvrC motif 139 173 9.9E-7 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS27825 ebf632a00a29e392c4389a0c2096edff 182 SUPERFAMILY SSF46600 138 174 2.88E-6 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS27825 ebf632a00a29e392c4389a0c2096edff 182 PIRSF PIRSF015034 1 182 1.3E-61 T 29-03-2018 IPR025542 YacH protein CSW12_RS27825 ebf632a00a29e392c4389a0c2096edff 182 Gene3D G3DSA:4.10.860.10 103 178 7.3E-10 T 29-03-2018 IPR001943 UVR domain GO:0005515 CSW12_RS05195 a08d12c64a633e2e98c3c47da00cea64 213 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 13 195 5.2E-12 T 29-03-2018 IPR006490 Phage major tail protein, phi13 family CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 307 8.2E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 Hamap MF_01685 Ferredoxin--NADP reductase. 6 333 37.393 T 29-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.8E-18 T 29-03-2018 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 7.8E-18 T 29-03-2018 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 7.8E-18 T 29-03-2018 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 292 7.8E-18 T 29-03-2018 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 Gene3D G3DSA:3.50.50.60 145 320 8.7E-14 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 SUPERFAMILY SSF51905 1 318 3.11E-39 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 1.8E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 1.8E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 1.8E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.8E-19 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS00595 c610a3258f822bf125536f3c3183db01 349 Gene3D G3DSA:3.50.50.60 1 140 8.6E-18 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS18260 1529c11d6beb6e586996be8c7d26bdb9 143 SUPERFAMILY SSF46785 2 137 4.36E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18260 1529c11d6beb6e586996be8c7d26bdb9 143 Pfam PF02082 Transcriptional regulator 1 81 5.0E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS18260 1529c11d6beb6e586996be8c7d26bdb9 143 Gene3D G3DSA:1.10.10.10 1 143 4.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25900 52263d56d44d4cae462f9df362460345 121 PIRSF PIRSF031804 1 110 5.2E-43 T 29-03-2018 IPR016983 Uncharacterised conserved protein UCP031804 CSW12_RS25900 52263d56d44d4cae462f9df362460345 121 Pfam PF06803 Protein of unknown function (DUF1232) 45 80 1.4E-13 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CSW12_RS16835 c4049d5e866d7fd1e666e00a2f6419b4 218 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 14 214 9.3E-74 T 29-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CSW12_RS16835 c4049d5e866d7fd1e666e00a2f6419b4 218 Pfam PF03006 Haemolysin-III related 13 206 1.9E-42 T 29-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CSW12_RS06115 c620dac030819b04188061aeb74f469c 160 TIGRFAM TIGR02132 phaR_Bmeg: polyhydroxyalkanoic acid synthase, PhaR subunit 2 135 1.4E-76 T 29-03-2018 IPR011729 Polyhydroxyalkanoic acid synthase, PhaR subunit CSW12_RS06115 c620dac030819b04188061aeb74f469c 160 Gene3D G3DSA:1.20.5.50 50 157 1.1E-5 T 29-03-2018 CSW12_RS21250 d089a707abde14f23ab5a40f6ddf7f09 185 Gene3D G3DSA:3.40.140.10 3 147 1.3E-39 T 29-03-2018 CSW12_RS21250 d089a707abde14f23ab5a40f6ddf7f09 185 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 1.5E-28 T 29-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CSW12_RS21250 d089a707abde14f23ab5a40f6ddf7f09 185 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 29-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CSW12_RS21250 d089a707abde14f23ab5a40f6ddf7f09 185 PIRSF PIRSF006019 1 151 4.6E-58 T 29-03-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CSW12_RS21250 d089a707abde14f23ab5a40f6ddf7f09 185 SUPERFAMILY SSF53927 7 145 1.09E-40 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS21250 d089a707abde14f23ab5a40f6ddf7f09 185 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 151 1.1E-90 T 29-03-2018 IPR013404 Competence operon E, ComEB CSW12_RS26605 c339992bea0e2c8a38e09fbd1e5ab93a 145 SUPERFAMILY SSF50814 7 143 1.62E-37 T 29-03-2018 IPR012674 Calycin CSW12_RS26605 c339992bea0e2c8a38e09fbd1e5ab93a 145 Gene3D G3DSA:2.40.128.20 2 145 2.1E-37 T 29-03-2018 IPR012674 Calycin CSW12_RS26605 c339992bea0e2c8a38e09fbd1e5ab93a 145 Pfam PF09148 Domain of unknown function (DUF1934) 13 139 7.1E-29 T 29-03-2018 IPR015231 Protein of unknown function DUF1934 CSW12_RS26615 654bbdcbe261eb943e2b27cf030b6365 120 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 2 116 4.2E-10 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS26615 654bbdcbe261eb943e2b27cf030b6365 120 Pfam PF06486 Protein of unknown function (DUF1093) 43 107 2.4E-10 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS26615 654bbdcbe261eb943e2b27cf030b6365 120 SUPERFAMILY SSF159121 39 118 4.71E-19 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 Gene3D G3DSA:2.30.42.10 118 223 2.5E-15 T 29-03-2018 CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 7 422 7.5E-182 T 29-03-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 SUPERFAMILY SSF50494 354 416 7.63E-7 T 29-03-2018 IPR009003 Peptidase S1, PA clan CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 Pfam PF13180 PDZ domain 141 194 2.7E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 Gene3D G3DSA:2.40.10.10 315 413 7.6E-5 T 29-03-2018 CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 Pfam PF05580 SpoIVB peptidase S55 209 417 4.1E-85 T 29-03-2018 IPR008763 Peptidase S55, SpoIVB CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 SUPERFAMILY SSF50156 143 228 5.39E-11 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS20450 ea871f5e6fa722640f92538f1fc2ebca 432 SMART SM00228 116 192 5.2E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS04580 8e0d5056aba87c3655f8eb91fbac66d8 482 Pfam PF03703 Bacterial PH domain 401 476 2.2E-10 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04580 8e0d5056aba87c3655f8eb91fbac66d8 482 Pfam PF03703 Bacterial PH domain 55 133 4.8E-16 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04580 8e0d5056aba87c3655f8eb91fbac66d8 482 Pfam PF03703 Bacterial PH domain 252 333 5.1E-11 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04580 8e0d5056aba87c3655f8eb91fbac66d8 482 PIRSF PIRSF026631 1 482 4.1E-143 T 29-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CSW12_RS13445 33c4f734920a5e153cc634f9fd96aac1 540 Gene3D G3DSA:3.10.105.10 304 510 6.7E-49 T 29-03-2018 CSW12_RS13445 33c4f734920a5e153cc634f9fd96aac1 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 459 2.8E-76 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS13445 33c4f734920a5e153cc634f9fd96aac1 540 PIRSF PIRSF002741 1 540 8.2E-98 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS13445 33c4f734920a5e153cc634f9fd96aac1 540 Gene3D G3DSA:3.40.190.10 169 303 1.5E-35 T 29-03-2018 CSW12_RS13445 33c4f734920a5e153cc634f9fd96aac1 540 Gene3D G3DSA:3.90.76.10 60 168 4.5E-31 T 29-03-2018 CSW12_RS13445 33c4f734920a5e153cc634f9fd96aac1 540 SUPERFAMILY SSF53850 35 529 7.42E-123 T 29-03-2018 CSW12_RS26760 eac1a0b70f36f7da9b68459e92e61471 433 Pfam PF00860 Permease family 8 392 9.9E-60 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 ProSitePatterns PS01235 PdxS/SNZ family signature. 206 224 - T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 PIRSF PIRSF029271 1 295 6.2E-155 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 Pfam PF01680 SOR/SNZ family 8 213 2.7E-106 T 29-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 Gene3D G3DSA:3.20.20.70 19 272 9.1E-71 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 5 295 54.923 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 10 295 1.0E-156 T 29-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27380 6ac9c80438a2a9cf52e6f6d4573775e9 295 SUPERFAMILY SSF51366 19 267 2.21E-69 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS03135 ae971b82e27c06e729a0a047c1f0e925 472 Pfam PF04293 SpoVR like protein 7 410 2.1E-163 T 29-03-2018 IPR007390 Sporulation stage V, protein R CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 Gene3D G3DSA:3.40.47.10 30 299 3.6E-61 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 SUPERFAMILY SSF53901 38 303 1.96E-84 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 Pfam PF02803 Thiolase, C-terminal domain 305 425 5.1E-45 T 29-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 40 425 5.1E-141 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 Gene3D G3DSA:3.40.47.10 300 424 2.1E-32 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 Pfam PF00108 Thiolase, N-terminal domain 39 297 1.7E-98 T 29-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 ProSitePatterns PS00099 Thiolases active site. 408 421 - T 29-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 PIRSF PIRSF000429 32 427 1.7E-124 T 29-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 118 136 - T 29-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 ProSitePatterns PS00737 Thiolases signature 2. 373 389 - T 29-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CSW12_RS26515 0d72a7faca9574e4be283008d4d267e3 427 SUPERFAMILY SSF53901 305 426 6.55E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 Gene3D G3DSA:3.50.50.60 426 482 0.095 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 SUPERFAMILY SSF51905 22 339 3.67E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 SUPERFAMILY SSF51905 443 481 3.67E-60 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 Pfam PF01593 Flavin containing amine oxidoreductase 33 480 9.5E-79 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 Gene3D G3DSA:3.90.660.10 47 133 3.5E-23 T 29-03-2018 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 Gene3D G3DSA:3.90.660.10 225 425 2.1E-39 T 29-03-2018 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 PRINTS PR00757 Flavin-containing amine oxidase signature 25 44 4.3E-8 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 PRINTS PR00757 Flavin-containing amine oxidase signature 462 479 4.3E-8 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 PRINTS PR00757 Flavin-containing amine oxidase signature 325 344 4.3E-8 T 29-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 SUPERFAMILY SSF54373 321 431 8.5E-31 T 29-03-2018 CSW12_RS17765 c639eee2fd1a95a89eaad99c100f33c6 482 Gene3D G3DSA:1.10.405.10 134 224 3.8E-23 T 29-03-2018 CSW12_RS00165 f49ddc15b8a7afc3d5fa8e65325073f6 353 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 57 113 1.3E-11 T 29-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CSW12_RS00165 f49ddc15b8a7afc3d5fa8e65325073f6 353 Pfam PF00589 Phage integrase family 167 337 1.7E-28 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS00165 f49ddc15b8a7afc3d5fa8e65325073f6 353 Gene3D G3DSA:1.10.443.10 159 339 1.8E-36 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS00165 f49ddc15b8a7afc3d5fa8e65325073f6 353 SUPERFAMILY SSF56349 56 345 4.12E-66 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS00165 f49ddc15b8a7afc3d5fa8e65325073f6 353 Gene3D G3DSA:1.10.150.130 56 139 3.7E-16 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS00165 f49ddc15b8a7afc3d5fa8e65325073f6 353 Pfam PF14657 Arm DNA-binding domain 11 54 8.8E-12 T 29-03-2018 IPR028259 AP2-like integrase, N-terminal domain CSW12_RS04655 576d2213fc6d991eed73d4e85b2e1177 165 Gene3D G3DSA:3.30.70.100 49 165 6.4E-22 T 29-03-2018 CSW12_RS04655 576d2213fc6d991eed73d4e85b2e1177 165 SUPERFAMILY SSF54909 56 139 1.61E-24 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS04655 576d2213fc6d991eed73d4e85b2e1177 165 Pfam PF03992 Antibiotic biosynthesis monooxygenase 56 129 1.2E-14 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 PIRSF PIRSF005814 572 633 0.32 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 PIRSF PIRSF005814 1 584 2.1E-209 T 29-03-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 SMART SM00534 323 508 9.9E-54 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 Gene3D G3DSA:1.10.1420.10 12 286 5.2E-5 T 29-03-2018 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 SUPERFAMILY SSF48334 21 284 2.22E-21 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 Pfam PF00488 MutS domain V 326 507 4.8E-32 T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 405 421 - T 29-03-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 Gene3D G3DSA:3.40.50.300 288 513 6.8E-30 T 29-03-2018 CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 SUPERFAMILY SSF52540 289 511 2.39E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS10500 520ee377254e6c6996824c7cf68222ec 633 SMART SM00533 9 311 1.5E-20 T 29-03-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CSW12_RS24440 3e0584f0d6aee70c8fbbb0c65309ee4b 293 Pfam PF13730 Helix-turn-helix domain 34 92 2.7E-12 T 29-03-2018 CSW12_RS24440 3e0584f0d6aee70c8fbbb0c65309ee4b 293 SUPERFAMILY SSF46785 23 110 1.48E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24440 3e0584f0d6aee70c8fbbb0c65309ee4b 293 Gene3D G3DSA:1.10.10.10 15 172 4.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21420 9256c85dc347f1b870f1fd72fec4408d 104 Gene3D G3DSA:3.30.1360.20 3 101 8.2E-26 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CSW12_RS21420 9256c85dc347f1b870f1fd72fec4408d 104 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 93 5.7E-23 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CSW12_RS21420 9256c85dc347f1b870f1fd72fec4408d 104 SUPERFAMILY SSF55248 4 94 1.96E-25 T 29-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 SUPERFAMILY SSF53067 7 253 9.88E-72 T 29-03-2018 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 SUPERFAMILY SSF53067 252 501 4.98E-70 T 29-03-2018 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 PIRSF PIRSF000538 5 505 1.4E-151 T 29-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 510 3.4E-200 T 29-03-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 250 8.0E-72 T 29-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 454 5.2E-38 T 29-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 Gene3D G3DSA:3.30.420.40 252 512 9.6E-69 T 29-03-2018 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 29-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CSW12_RS16620 b26234f16be408142cbf77dee3535794 512 Gene3D G3DSA:3.30.420.40 1 251 2.0E-71 T 29-03-2018 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 PRINTS PR00113 Alkaline phosphatase signature 252 281 1.5E-46 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 PRINTS PR00113 Alkaline phosphatase signature 99 114 1.5E-46 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 PRINTS PR00113 Alkaline phosphatase signature 44 64 1.5E-46 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 PRINTS PR00113 Alkaline phosphatase signature 186 196 1.5E-46 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 PRINTS PR00113 Alkaline phosphatase signature 136 156 1.5E-46 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 ProSitePatterns PS00123 Alkaline phosphatase active site. 99 107 - T 29-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 SMART SM00098 45 454 1.2E-187 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 Gene3D G3DSA:3.40.720.10 18 461 3.0E-130 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 Pfam PF00245 Alkaline phosphatase 44 450 1.9E-131 T 29-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CSW12_RS30620 83af5fb13369a7b1c50ed44e8b64e59b 461 SUPERFAMILY SSF53649 36 452 4.25E-131 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS01630 e49324439e954041cd8c14dbd35f6abe 170 Gene3D G3DSA:3.40.630.30 1 170 7.8E-29 T 29-03-2018 CSW12_RS01630 e49324439e954041cd8c14dbd35f6abe 170 Pfam PF00583 Acetyltransferase (GNAT) family 37 140 2.1E-19 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS01630 e49324439e954041cd8c14dbd35f6abe 170 SUPERFAMILY SSF55729 6 168 6.08E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.8E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 SUPERFAMILY SSF51735 2 251 1.16E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 Gene3D G3DSA:3.40.50.720 2 167 4.6E-28 T 29-03-2018 CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 252 2.3E-39 T 29-03-2018 CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 Gene3D G3DSA:3.40.50.720 168 251 9.2E-19 T 29-03-2018 CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS11275 d106226af43e373d6d496d4e5a6fe991 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.2E-6 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS20205 286ca1124028eb7759f84bff94ee4b94 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 35 408 0.0 T 29-03-2018 CSW12_RS20205 286ca1124028eb7759f84bff94ee4b94 408 SUPERFAMILY SSF56266 19 404 2.22E-138 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CSW12_RS20205 286ca1124028eb7759f84bff94ee4b94 408 Gene3D G3DSA:3.60.70.12 11 281 6.1E-102 T 29-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CSW12_RS20205 286ca1124028eb7759f84bff94ee4b94 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 14 408 3.7E-153 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CSW12_RS20205 286ca1124028eb7759f84bff94ee4b94 408 Pfam PF01960 ArgJ family 26 408 1.0E-146 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CSW12_RS20205 286ca1124028eb7759f84bff94ee4b94 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 141.201 T 29-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 9.0E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 9.0E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 9.0E-14 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 Pfam PF01022 Bacterial regulatory protein, arsR family 29 77 9.7E-13 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 SMART SM00418 22 101 3.0E-16 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 SUPERFAMILY SSF46785 16 99 3.81E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10410 dd4821c5f7f3bc0cd5eb0dce2730fcc0 114 Gene3D G3DSA:1.10.10.10 1 99 8.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04100 6a24de2f92dcd02e991513640854926a 123 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 123 1.0E-53 T 29-03-2018 CSW12_RS04100 6a24de2f92dcd02e991513640854926a 123 Pfam PF03899 ATP synthase I chain 10 103 3.7E-13 T 29-03-2018 IPR005598 ATP synthase protein I CSW12_RS07515 21a1c50b9c92a681a2f4847eeeffdf4b 259 Gene3D G3DSA:3.60.110.10 1 259 2.3E-80 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CSW12_RS07515 21a1c50b9c92a681a2f4847eeeffdf4b 259 Pfam PF00795 Carbon-nitrogen hydrolase 2 245 1.8E-51 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CSW12_RS07515 21a1c50b9c92a681a2f4847eeeffdf4b 259 SUPERFAMILY SSF56317 1 258 8.63E-77 T 29-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CSW12_RS01700 c9cb5fef0275344b0d819f10c78f5ce6 487 SUPERFAMILY SSF51690 139 478 1.47E-131 T 29-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CSW12_RS01700 c9cb5fef0275344b0d819f10c78f5ce6 487 PIRSF PIRSF000484 2 480 1.4E-157 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CSW12_RS01700 c9cb5fef0275344b0d819f10c78f5ce6 487 SUPERFAMILY SSF54675 5 138 2.69E-48 T 29-03-2018 CSW12_RS01700 c9cb5fef0275344b0d819f10c78f5ce6 487 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 10 465 3.0E-179 T 29-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CSW12_RS01700 c9cb5fef0275344b0d819f10c78f5ce6 487 Gene3D G3DSA:3.20.140.10 6 387 2.3E-128 T 29-03-2018 CSW12_RS01700 c9cb5fef0275344b0d819f10c78f5ce6 487 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 155 336 1.2E-12 T 29-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CSW12_RS14585 4d7a74b663f8fa746c37c208d118f0a5 165 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 1.3E-17 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS14585 4d7a74b663f8fa746c37c208d118f0a5 165 SUPERFAMILY SSF46785 4 164 1.3E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14585 4d7a74b663f8fa746c37c208d118f0a5 165 Gene3D G3DSA:1.10.10.10 1 92 1.5E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 Gene3D G3DSA:2.60.40.1180 428 513 6.1E-33 T 29-03-2018 CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 Pfam PF00128 Alpha amylase, catalytic domain 64 402 3.4E-24 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 PIRSF PIRSF001021 8 513 2.2E-235 T 29-03-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 SMART SM00642 33 421 9.5E-72 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 SUPERFAMILY SSF51445 34 413 1.74E-105 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 Gene3D G3DSA:3.20.20.80 32 426 9.6E-79 T 29-03-2018 CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 SUPERFAMILY SSF51011 424 513 1.58E-35 T 29-03-2018 CSW12_RS10490 ff33a78f3b71da40ab850d3aa6fdd133 513 Pfam PF09154 Domain of unknown function (DUF1939) 465 510 1.9E-7 T 29-03-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 Gene3D G3DSA:3.20.20.70 7 249 3.1E-59 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 29-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 PIRSF PIRSF006621 1 330 1.7E-106 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 SUPERFAMILY SSF51395 11 322 4.76E-90 T 29-03-2018 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 Gene3D G3DSA:1.10.1200.80 253 330 1.6E-20 T 29-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 Pfam PF01207 Dihydrouridine synthase (Dus) 14 319 1.3E-110 T 29-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CSW12_RS27735 adddaa9b39d8ad1415c4ae2fb52c447e 332 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 322 1.5E-134 T 29-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CSW12_RS22210 b98a4b97c71755defeb0ee211e78be0b 257 SMART SM00893 21 211 1.9E-54 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CSW12_RS22210 b98a4b97c71755defeb0ee211e78be0b 257 Gene3D G3DSA:3.40.50.620 1 257 1.2E-71 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS22210 b98a4b97c71755defeb0ee211e78be0b 257 SUPERFAMILY SSF52402 1 246 5.12E-74 T 29-03-2018 CSW12_RS22210 b98a4b97c71755defeb0ee211e78be0b 257 Pfam PF01012 Electron transfer flavoprotein domain 28 206 3.4E-47 T 29-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CSW12_RS22210 b98a4b97c71755defeb0ee211e78be0b 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 29-03-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CSW12_RS22210 b98a4b97c71755defeb0ee211e78be0b 257 PIRSF PIRSF000090 1 257 9.7E-75 T 29-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CSW12_RS29755 90230ffe6f013763ec148d7d09abac31 396 Gene3D G3DSA:3.30.420.40 7 220 1.2E-24 T 29-03-2018 CSW12_RS29755 90230ffe6f013763ec148d7d09abac31 396 Gene3D G3DSA:3.30.420.150 228 389 2.2E-4 T 29-03-2018 CSW12_RS29755 90230ffe6f013763ec148d7d09abac31 396 SUPERFAMILY SSF53067 227 382 1.15E-9 T 29-03-2018 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 400 3.9E-18 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 279 5.1E-69 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 SUPERFAMILY SSF69189 291 380 1.12E-15 T 29-03-2018 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 SUPERFAMILY SSF56601 1 299 4.93E-74 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 Gene3D G3DSA:2.60.410.10 299 400 3.6E-12 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 7.7E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 7.7E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 7.7E-10 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 SMART SM00936 299 400 1.1E-9 T 29-03-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CSW12_RS26725 840593ea3e669d85c578bed912b6c062 423 Gene3D G3DSA:3.40.710.10 20 298 1.7E-44 T 29-03-2018 CSW12_RS05735 b36e66c644ee073f4605a8045d5f8e2a 204 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 202 39.146 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CSW12_RS05735 b36e66c644ee073f4605a8045d5f8e2a 204 SUPERFAMILY SSF51366 1 199 1.11E-56 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS05735 b36e66c644ee073f4605a8045d5f8e2a 204 Gene3D G3DSA:3.20.20.70 1 202 1.8E-74 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS05735 b36e66c644ee073f4605a8045d5f8e2a 204 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 196 1.4E-51 T 29-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CSW12_RS15830 275323020d0736e786cc9893416e9397 185 SUPERFAMILY SSF51182 51 183 1.76E-24 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS15830 275323020d0736e786cc9893416e9397 185 Gene3D G3DSA:1.10.260.40 1 73 2.4E-15 T 29-03-2018 CSW12_RS15830 275323020d0736e786cc9893416e9397 185 SMART SM00530 11 66 7.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15830 275323020d0736e786cc9893416e9397 185 Gene3D G3DSA:2.60.120.10 74 184 1.1E-14 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS15830 275323020d0736e786cc9893416e9397 185 Pfam PF01381 Helix-turn-helix 12 64 1.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15830 275323020d0736e786cc9893416e9397 185 Pfam PF07883 Cupin domain 117 172 8.6E-12 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS15830 275323020d0736e786cc9893416e9397 185 SUPERFAMILY SSF47413 3 72 1.74E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS18775 8d346f41541002f91efc3ea50c9fe9fa 149 Gene3D G3DSA:1.10.260.40 1 146 4.1E-26 T 29-03-2018 CSW12_RS18775 8d346f41541002f91efc3ea50c9fe9fa 149 SUPERFAMILY SSF47413 1 66 7.24E-20 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS18775 8d346f41541002f91efc3ea50c9fe9fa 149 SMART SM00530 6 61 1.3E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS18775 8d346f41541002f91efc3ea50c9fe9fa 149 Pfam PF01381 Helix-turn-helix 7 61 1.0E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS11850 841154291217ab8ebfb1f8380833f6c4 445 PIRSF PIRSF036794 23 445 2.9E-147 T 29-03-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type CSW12_RS11850 841154291217ab8ebfb1f8380833f6c4 445 SUPERFAMILY SSF159501 36 444 2.49E-107 T 29-03-2018 CSW12_RS11850 841154291217ab8ebfb1f8380833f6c4 445 Pfam PF05139 Erythromycin esterase 101 439 8.4E-64 T 29-03-2018 IPR007815 Erythromycin esterase GO:0046677 CSW12_RS11850 841154291217ab8ebfb1f8380833f6c4 445 Gene3D G3DSA:3.40.1660.10 33 169 6.3E-26 T 29-03-2018 CSW12_RS11850 841154291217ab8ebfb1f8380833f6c4 445 Gene3D G3DSA:3.40.1660.10 224 445 6.8E-26 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 PIRSF PIRSF015589 3 702 3.4E-279 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Gene3D G3DSA:3.30.870.10 516 702 4.5E-32 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Hamap MF_00347 Polyphosphate kinase [ppk]. 15 697 29.963 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Gene3D G3DSA:3.30.1840.10 123 314 3.8E-70 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Gene3D G3DSA:1.20.58.310 19 122 4.7E-39 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 16 693 6.9E-285 T 29-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 SUPERFAMILY SSF56024 332 512 5.97E-57 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Pfam PF02503 Polyphosphate kinase middle domain 132 337 1.8E-70 T 29-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 SUPERFAMILY SSF140356 14 117 4.45E-39 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Gene3D G3DSA:3.30.870.10 333 515 9.7E-19 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 SUPERFAMILY SSF56024 516 698 2.92E-71 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Pfam PF13090 Polyphosphate kinase C-terminal domain 346 692 4.9E-155 T 29-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 SUPERFAMILY SSF143724 121 318 4.51E-61 T 29-03-2018 CSW12_RS07765 f67769028570b52d7121bc3bf56e5dcd 702 Pfam PF13089 Polyphosphate kinase N-terminal domain 17 122 4.7E-40 T 29-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CSW12_RS29285 3570b64eddc212563d9b77eccf6259e4 136 SMART SM00530 7 62 2.0E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29285 3570b64eddc212563d9b77eccf6259e4 136 Gene3D G3DSA:1.10.260.40 1 134 7.4E-19 T 29-03-2018 CSW12_RS29285 3570b64eddc212563d9b77eccf6259e4 136 Pfam PF01381 Helix-turn-helix 8 62 4.3E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29285 3570b64eddc212563d9b77eccf6259e4 136 SUPERFAMILY SSF47413 1 66 1.32E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS01405 ec5b8330e388418f5c72e0bd84056af0 153 PRINTS PR00502 NUDIX hydrolase family signature 49 64 1.7E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS01405 ec5b8330e388418f5c72e0bd84056af0 153 PRINTS PR00502 NUDIX hydrolase family signature 35 49 1.7E-8 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS01405 ec5b8330e388418f5c72e0bd84056af0 153 SUPERFAMILY SSF55811 5 140 1.06E-28 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS01405 ec5b8330e388418f5c72e0bd84056af0 153 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS01405 ec5b8330e388418f5c72e0bd84056af0 153 Gene3D G3DSA:3.90.79.10 1 138 1.7E-25 T 29-03-2018 CSW12_RS01405 ec5b8330e388418f5c72e0bd84056af0 153 Pfam PF00293 NUDIX domain 9 112 1.3E-20 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 PIRSF PIRSF000097 3 274 5.3E-91 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 PRINTS PR00069 Aldo-keto reductase signature 127 144 2.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 PRINTS PR00069 Aldo-keto reductase signature 97 115 2.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 PRINTS PR00069 Aldo-keto reductase signature 198 222 2.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 PRINTS PR00069 Aldo-keto reductase signature 41 65 2.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 PRINTS PR00069 Aldo-keto reductase signature 161 190 2.0E-52 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 Pfam PF00248 Aldo/keto reductase family 30 263 4.1E-52 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 127 144 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 231 246 - T 29-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 SUPERFAMILY SSF51430 9 271 3.27E-95 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS28425 78d091b70f817dc46c5238e1b8b1832d 277 Gene3D G3DSA:3.20.20.100 4 277 1.1E-101 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 Gene3D G3DSA:3.90.660.20 200 409 1.7E-45 T 29-03-2018 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 Gene3D G3DSA:3.90.660.20 46 118 7.8E-11 T 29-03-2018 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 Pfam PF01593 Flavin containing amine oxidoreductase 12 459 4.2E-71 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 SUPERFAMILY SSF51905 3 317 5.4E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 SUPERFAMILY SSF51905 427 459 5.4E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 462 2.5E-129 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 Gene3D G3DSA:1.10.3110.10 119 199 2.5E-29 T 29-03-2018 CSW12_RS04675 fdd68192acb374e1fc2fa55aa9dd6308 475 SUPERFAMILY SSF54373 301 409 8.34E-35 T 29-03-2018 CSW12_RS10890 7e34b95a519d8981187dd981e8329a15 275 SMART SM00849 76 246 5.0E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10890 7e34b95a519d8981187dd981e8329a15 275 SUPERFAMILY SSF56281 59 232 5.74E-26 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10890 7e34b95a519d8981187dd981e8329a15 275 Pfam PF00753 Metallo-beta-lactamase superfamily 77 210 2.0E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10890 7e34b95a519d8981187dd981e8329a15 275 Gene3D G3DSA:3.60.15.10 54 265 1.6E-20 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS13565 98cd7134ee530cc4f8c216ea3ddfb9ff 548 Gene3D G3DSA:1.10.1370.10 35 521 3.1E-35 T 29-03-2018 CSW12_RS13565 98cd7134ee530cc4f8c216ea3ddfb9ff 548 SUPERFAMILY SSF55486 20 518 2.05E-64 T 29-03-2018 CSW12_RS13565 98cd7134ee530cc4f8c216ea3ddfb9ff 548 Pfam PF01432 Peptidase family M3 155 510 1.3E-29 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CSW12_RS13565 98cd7134ee530cc4f8c216ea3ddfb9ff 548 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 3 548 1.0E-209 T 29-03-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related CSW12_RS05445 eb769846d14959ac835cf2e5323042cd 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 7.2E-36 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05445 eb769846d14959ac835cf2e5323042cd 309 Gene3D G3DSA:1.10.3720.10 2 292 1.2E-39 T 29-03-2018 CSW12_RS05445 eb769846d14959ac835cf2e5323042cd 309 SUPERFAMILY SSF161098 89 291 9.81E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS11915 e85b0a800087d0da63f22fb3ce727292 695 SUPERFAMILY SSF56601 56 377 6.69E-71 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11915 e85b0a800087d0da63f22fb3ce727292 695 Gene3D G3DSA:3.40.710.10 29 390 2.3E-70 T 29-03-2018 CSW12_RS11915 e85b0a800087d0da63f22fb3ce727292 695 Pfam PF00144 Beta-lactamase 58 376 4.5E-60 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 Gene3D G3DSA:1.10.10.10 122 233 5.3E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 229 6.3E-30 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 Gene3D G3DSA:3.40.50.2300 1 121 3.3E-36 T 29-03-2018 CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 SUPERFAMILY SSF52172 5 188 9.81E-41 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 SMART SM00448 4 114 2.1E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 Pfam PF00072 Response regulator receiver domain 6 115 8.1E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS28870 a6aa99ec225d778e4151be121515ddc7 233 SMART SM00862 153 229 2.7E-29 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 Gene3D G3DSA:1.20.1250.20 6 206 1.0E-34 T 29-03-2018 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 17 398 3.5E-108 T 29-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 Gene3D G3DSA:1.20.1250.20 208 415 2.6E-21 T 29-03-2018 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 Pfam PF07690 Major Facilitator Superfamily 26 365 4.2E-48 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 PRINTS PR01035 Tetracycline resistance protein signature 286 307 8.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 PRINTS PR01035 Tetracycline resistance protein signature 29 45 8.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 PRINTS PR01035 Tetracycline resistance protein signature 173 193 8.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 PRINTS PR01035 Tetracycline resistance protein signature 113 134 8.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 PRINTS PR01035 Tetracycline resistance protein signature 86 110 8.4E-8 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS28360 0269ca26d2d92b13c9f9c79e7e6fda3b 416 SUPERFAMILY SSF103473 9 404 3.01E-71 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 Gene3D G3DSA:4.10.372.10 570 663 0.25 T 29-03-2018 IPR027433 Lipoxygenase, domain 3 CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 Gene3D G3DSA:3.40.50.200 140 495 5.3E-29 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 Pfam PF03272 Putative mucin or carbohydrate-binding module 517 630 5.5E-28 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 Pfam PF03272 Putative mucin or carbohydrate-binding module 785 903 6.9E-27 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 Pfam PF03272 Putative mucin or carbohydrate-binding module 651 764 3.8E-28 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 PRINTS PR00723 Subtilisin serine protease family (S8) signature 241 254 9.8E-7 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 PRINTS PR00723 Subtilisin serine protease family (S8) signature 207 226 9.8E-7 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 PRINTS PR00723 Subtilisin serine protease family (S8) signature 428 444 9.8E-7 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 429 439 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 SUPERFAMILY SSF52743 187 468 6.55E-34 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS10210 ada8c7c740f111f6390532122badb788 907 Pfam PF00082 Subtilase family 209 472 1.4E-14 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS27530 5acdf31ff9e6bcdd39bafe3f6143e986 94 SMART SM00966 8 51 6.6E-10 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS27530 5acdf31ff9e6bcdd39bafe3f6143e986 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 8.8E-12 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS27530 5acdf31ff9e6bcdd39bafe3f6143e986 94 Gene3D G3DSA:2.10.260.10 1 48 9.0E-21 T 29-03-2018 CSW12_RS27530 5acdf31ff9e6bcdd39bafe3f6143e986 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 4.6E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS27530 5acdf31ff9e6bcdd39bafe3f6143e986 94 SUPERFAMILY SSF89447 1 52 1.23E-16 T 29-03-2018 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 41.908 T 29-03-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 PIRSF PIRSF000164 1 303 8.7E-86 T 29-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Gene3D G3DSA:3.20.20.70 1 309 2.2E-64 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 Pfam PF01180 Dihydroorotate dehydrogenase 4 286 2.6E-96 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 SUPERFAMILY SSF51395 1 301 2.43E-88 T 29-03-2018 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 1.7E-127 T 29-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CSW12_RS08335 74f8fa4fb3b06bed8ffea23e0b15afe1 309 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 29-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CSW12_RS05635 d5e03136e7661e797e47b9fb0cfffa97 199 Pfam PF14153 Spore coat protein CotO 13 199 8.0E-56 T 29-03-2018 IPR025439 Spore coat protein CotO CSW12_RS05635 d5e03136e7661e797e47b9fb0cfffa97 199 Gene3D G3DSA:2.130.10.10 42 195 3.4E-7 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS05635 d5e03136e7661e797e47b9fb0cfffa97 199 Pfam PF07133 Merozoite surface protein (SPAM) 45 141 7.5E-7 T 29-03-2018 IPR010784 Merozoite surface protein-type CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SUPERFAMILY SSF158911 49 167 1.44E-29 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SUPERFAMILY SSF52058 222 498 4.76E-50 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF00395 S-layer homology domain 654 695 7.5E-11 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF00395 S-layer homology domain 714 757 1.3E-11 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF00395 S-layer homology domain 594 636 4.2E-10 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF12799 Leucine Rich repeats (2 copies) 423 464 1.2E-6 T 29-03-2018 IPR025875 Leucine rich repeat 4 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF12799 Leucine Rich repeats (2 copies) 337 377 3.0E-7 T 29-03-2018 IPR025875 Leucine rich repeat 4 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF12799 Leucine Rich repeats (2 copies) 293 333 2.4E-10 T 29-03-2018 IPR025875 Leucine rich repeat 4 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00369 291 311 23.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00369 313 334 75.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00369 444 467 9.1 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00369 422 443 390.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00369 335 358 54.0 T 29-03-2018 IPR003591 Leucine-rich repeat, typical subtype CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Pfam PF05031 Iron Transport-associated domain 48 164 3.7E-29 T 29-03-2018 IPR006635 NEAT domain CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 291 312 0.17 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 378 399 410.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 422 443 94.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 357 375 220.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 313 331 39.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 466 487 81.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 335 356 110.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 400 421 3.4 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00365 444 465 24.0 T 29-03-2018 CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Gene3D G3DSA:3.80.10.10 368 501 2.6E-25 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Gene3D G3DSA:3.80.10.10 185 367 6.3E-35 T 29-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SMART SM00725 47 171 1.5E-10 T 29-03-2018 IPR006635 NEAT domain CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 SUPERFAMILY SSF81296 500 575 4.01E-11 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS06195 7166d01cc23883296ac1b2d7b8c07fe7 766 Gene3D G3DSA:2.60.40.1220 502 574 4.7E-14 T 29-03-2018 CSW12_RS11780 a385161d25d7967cf7e5d24e3b692333 571 SUPERFAMILY SSF56519 32 214 7.06E-31 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS11780 a385161d25d7967cf7e5d24e3b692333 571 Pfam PF00905 Penicillin binding protein transpeptidase domain 241 564 1.1E-43 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS11780 a385161d25d7967cf7e5d24e3b692333 571 Pfam PF03717 Penicillin-binding Protein dimerisation domain 37 191 2.0E-31 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS11780 a385161d25d7967cf7e5d24e3b692333 571 Gene3D G3DSA:3.40.710.10 216 571 2.0E-63 T 29-03-2018 CSW12_RS11780 a385161d25d7967cf7e5d24e3b692333 571 SUPERFAMILY SSF56601 169 568 6.24E-58 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11780 a385161d25d7967cf7e5d24e3b692333 571 Gene3D G3DSA:3.90.1310.10 29 215 2.6E-26 T 29-03-2018 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 392 2.5E-151 T 29-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 Gene3D G3DSA:3.40.50.10300 183 401 7.2E-70 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 Pfam PF02441 Flavoprotein 5 177 1.1E-43 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 SUPERFAMILY SSF102645 183 396 3.66E-77 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 SUPERFAMILY SSF52507 1 179 5.49E-59 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 366 1.3E-72 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CSW12_RS08425 153d7383efe188d620b89227229f3b26 401 Gene3D G3DSA:3.40.50.1950 1 182 1.0E-53 T 29-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CSW12_RS20275 b094d3a8947167a018b3733b0efbe433 234 PRINTS PR01837 MgtC/SapB protein signature 86 110 3.3E-45 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS20275 b094d3a8947167a018b3733b0efbe433 234 PRINTS PR01837 MgtC/SapB protein signature 33 51 3.3E-45 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS20275 b094d3a8947167a018b3733b0efbe433 234 PRINTS PR01837 MgtC/SapB protein signature 59 81 3.3E-45 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS20275 b094d3a8947167a018b3733b0efbe433 234 PRINTS PR01837 MgtC/SapB protein signature 14 33 3.3E-45 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS20275 b094d3a8947167a018b3733b0efbe433 234 Pfam PF02308 MgtC family 11 130 5.2E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 SUPERFAMILY SSF51735 43 286 1.03E-79 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 54 284 5.5E-59 T 29-03-2018 CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 180 208 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 183 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 132 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 212 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 46 63 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 248 268 1.3E-32 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 Gene3D G3DSA:3.40.50.720 2 287 1.1E-75 T 29-03-2018 CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 193 212 5.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 173 181 5.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS03070 27d331f2b8cb42c13a65477b17e56685 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 132 5.6E-8 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22065 7ab40e40bb1dfec25d183e4624effabb 349 Pfam PF10646 Sporulation and spore germination 212 324 4.2E-13 T 29-03-2018 IPR019606 GerMN domain CSW12_RS22065 7ab40e40bb1dfec25d183e4624effabb 349 Pfam PF10646 Sporulation and spore germination 64 175 3.2E-21 T 29-03-2018 IPR019606 GerMN domain CSW12_RS22065 7ab40e40bb1dfec25d183e4624effabb 349 SMART SM00909 89 179 1.1E-22 T 29-03-2018 IPR019606 GerMN domain CSW12_RS22065 7ab40e40bb1dfec25d183e4624effabb 349 SMART SM00909 241 329 8.6E-18 T 29-03-2018 IPR019606 GerMN domain CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 PIRSF PIRSF002599 1 67 1.0E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 SUPERFAMILY SSF50249 3 66 4.74E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.9E-29 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 Gene3D G3DSA:2.40.50.140 1 67 4.7E-26 T 29-03-2018 CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 SMART SM00357 4 67 2.6E-27 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 34 - T 29-03-2018 IPR019844 Cold-shock conserved site CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 PRINTS PR00050 Cold shock protein signature 40 58 3.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 PRINTS PR00050 Cold shock protein signature 5 20 3.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS04930 e0db9bdd2532054c81dd565627bf3a8b 67 PRINTS PR00050 Cold shock protein signature 25 34 3.0E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 SUPERFAMILY SSF52518 2 216 7.36E-66 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 Gene3D G3DSA:3.40.50.920 201 344 2.3E-39 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 Pfam PF02780 Transketolase, C-terminal domain 206 328 3.6E-43 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 SMART SM00861 5 192 4.6E-62 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 Pfam PF02779 Transketolase, pyrimidine binding domain 4 192 1.1E-55 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 Gene3D G3DSA:3.40.50.970 1 200 3.2E-66 T 29-03-2018 CSW12_RS13800 6a061a813c49b599192cbce47325e06f 344 SUPERFAMILY SSF52922 201 336 6.54E-42 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 PIRSF PIRSF000103 1 291 2.6E-71 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 163 2.4E-54 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 285 8.8E-36 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 Gene3D G3DSA:1.10.1040.10 177 291 3.0E-35 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 Gene3D G3DSA:3.40.50.720 1 176 3.9E-32 T 29-03-2018 CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 SUPERFAMILY SSF51735 6 167 6.11E-51 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07475 a127e2802c2457bcfda93b34782c36fa 292 SUPERFAMILY SSF48179 167 289 1.47E-39 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS17600 392e4bd2f9abbf11579e82f0ed1ba9da 215 PIRSF PIRSF035040 1 208 7.2E-88 T 29-03-2018 IPR017036 Uncharacterised conserved protein UCP035040, CBS-type CSW12_RS17600 392e4bd2f9abbf11579e82f0ed1ba9da 215 Gene3D G3DSA:3.10.580.10 2 106 4.5E-15 T 29-03-2018 CSW12_RS17600 392e4bd2f9abbf11579e82f0ed1ba9da 215 Pfam PF00571 CBS domain 9 59 2.8E-6 T 29-03-2018 IPR000644 CBS domain CSW12_RS17600 392e4bd2f9abbf11579e82f0ed1ba9da 215 Gene3D G3DSA:3.10.580.10 107 215 0.0093 T 29-03-2018 CSW12_RS17600 392e4bd2f9abbf11579e82f0ed1ba9da 215 SUPERFAMILY SSF54631 1 121 1.12E-20 T 29-03-2018 CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 SUPERFAMILY SSF52540 277 484 7.6E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 Pfam PF00005 ABC transporter 20 134 3.1E-21 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 Pfam PF00005 ABC transporter 310 437 3.5E-25 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 SUPERFAMILY SSF52540 4 214 3.09E-42 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 Gene3D G3DSA:3.40.50.300 1 215 1.7E-48 T 29-03-2018 CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 Gene3D G3DSA:3.40.50.300 253 515 1.8E-44 T 29-03-2018 CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 SMART SM00382 29 186 6.2E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 SMART SM00382 318 516 5.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14730 f3925dc206adaf71fbcf085bc9120209 542 Pfam PF12848 ABC transporter 174 268 3.6E-10 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS18335 df82160b3970b944b4af204f7e6768fb 211 SUPERFAMILY SSF141571 32 210 5.23E-44 T 29-03-2018 CSW12_RS18335 df82160b3970b944b4af204f7e6768fb 211 Pfam PF13599 Pentapeptide repeats (9 copies) 67 143 1.6E-12 T 29-03-2018 IPR001646 Pentapeptide repeat CSW12_RS18335 df82160b3970b944b4af204f7e6768fb 211 Gene3D G3DSA:2.160.10.20 118 209 2.5E-13 T 29-03-2018 CSW12_RS18335 df82160b3970b944b4af204f7e6768fb 211 Gene3D G3DSA:2.160.10.20 23 117 1.4E-19 T 29-03-2018 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 SUPERFAMILY SSF51735 1 161 1.53E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 Gene3D G3DSA:3.40.50.720 1 164 3.9E-31 T 29-03-2018 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 Gene3D G3DSA:1.10.1040.10 167 295 3.0E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 29-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 PIRSF PIRSF000103 1 294 3.3E-69 T 29-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 7.8E-46 T 29-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 285 1.6E-31 T 29-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CSW12_RS16270 75dd4f78e6d9016e04808921bbf4c529 296 SUPERFAMILY SSF48179 167 289 7.25E-33 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 Pfam PF00813 FliP family 55 245 8.7E-57 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 92 111 1.1E-44 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 72 92 1.1E-44 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 180 200 1.1E-44 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 225 250 1.1E-44 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 201 222 1.1E-44 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 53 72 1.1E-44 T 29-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 173 185 1.9E-6 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 123 137 1.9E-6 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 111 123 1.9E-6 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CSW12_RS19240 79186af04c2288da72ce2068b81f699f 252 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 51 60 1.9E-6 T 29-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 Gene3D G3DSA:3.40.50.720 156 268 1.3E-23 T 29-03-2018 CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 Pfam PF00107 Zinc-binding dehydrogenase 169 291 3.6E-27 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 Gene3D G3DSA:3.90.180.10 269 329 5.4E-5 T 29-03-2018 CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 SUPERFAMILY SSF50129 1 162 4.56E-30 T 29-03-2018 IPR011032 GroES-like CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 124 3.6E-13 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 SUPERFAMILY SSF51735 133 303 7.77E-37 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 SMART SM00829 11 326 9.4E-13 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS14435 7bcc53c4d4546ed7aac7f6864641ff2a 329 Gene3D G3DSA:3.90.180.10 1 155 5.4E-33 T 29-03-2018 CSW12_RS06665 31a53134cdec59d13b39ee5cbff726ef 628 SUPERFAMILY SSF53649 242 614 6.87E-72 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS06665 31a53134cdec59d13b39ee5cbff726ef 628 Gene3D G3DSA:3.40.720.10 236 543 3.6E-44 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS06665 31a53134cdec59d13b39ee5cbff726ef 628 PIRSF PIRSF005091 1 616 2.1E-175 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CSW12_RS06665 31a53134cdec59d13b39ee5cbff726ef 628 Pfam PF00884 Sulfatase 244 533 5.5E-38 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CSW12_RS17825 4b077f320361140fd825748bf6f83adf 175 Pfam PF04978 Protein of unknown function (DUF664) 20 166 1.8E-12 T 29-03-2018 IPR007061 Protein of unknown function DUF664 CSW12_RS17825 4b077f320361140fd825748bf6f83adf 175 SUPERFAMILY SSF109854 3 167 2.75E-36 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS17825 4b077f320361140fd825748bf6f83adf 175 Gene3D G3DSA:1.20.120.450 12 167 1.1E-16 T 29-03-2018 CSW12_RS30265 15de0de4b75c5f7e6d7378ca52953315 477 SUPERFAMILY SSF53098 6 474 4.48E-81 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS30265 15de0de4b75c5f7e6d7378ca52953315 477 Gene3D G3DSA:3.90.350.10 183 368 3.5E-24 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CSW12_RS30265 15de0de4b75c5f7e6d7378ca52953315 477 Pfam PF01609 Transposase DDE domain 119 385 6.0E-63 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CSW12_RS13000 6759c066785234b38e9e0c832780b71c 181 SUPERFAMILY SSF55729 5 171 1.53E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13000 6759c066785234b38e9e0c832780b71c 181 Pfam PF13302 Acetyltransferase (GNAT) domain 7 145 8.1E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13000 6759c066785234b38e9e0c832780b71c 181 Gene3D G3DSA:3.40.630.30 41 178 2.3E-25 T 29-03-2018 CSW12_RS05285 d05bb13272a83bbfe0c801b5db2783b5 410 Pfam PF00909 Ammonium Transporter Family 7 403 1.7E-130 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CSW12_RS05285 d05bb13272a83bbfe0c801b5db2783b5 410 Gene3D G3DSA:1.10.3430.10 1 384 2.3E-139 T 29-03-2018 CSW12_RS05285 d05bb13272a83bbfe0c801b5db2783b5 410 TIGRFAM TIGR00836 amt: ammonium transporter 5 403 2.0E-143 T 29-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CSW12_RS05285 d05bb13272a83bbfe0c801b5db2783b5 410 ProSitePatterns PS01219 Ammonium transporters signature. 160 185 - T 29-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CSW12_RS05285 d05bb13272a83bbfe0c801b5db2783b5 410 SUPERFAMILY SSF111352 2 384 2.48E-128 T 29-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CSW12_RS03175 d3e7e4b3fd0e963d4825b072c9d47a09 626 SUPERFAMILY SSF52540 411 498 3.2E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03175 d3e7e4b3fd0e963d4825b072c9d47a09 626 SUPERFAMILY SSF52540 131 196 3.2E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS03175 d3e7e4b3fd0e963d4825b072c9d47a09 626 SMART SM00382 132 495 1.2E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS03175 d3e7e4b3fd0e963d4825b072c9d47a09 626 Gene3D G3DSA:3.40.50.300 96 494 7.3E-25 T 29-03-2018 CSW12_RS03175 d3e7e4b3fd0e963d4825b072c9d47a09 626 Pfam PF02562 PhoH-like protein 130 180 1.6E-4 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CSW12_RS03175 d3e7e4b3fd0e963d4825b072c9d47a09 626 Pfam PF07728 AAA domain (dynein-related subfamily) 406 488 1.9E-10 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CSW12_RS11075 69ae91de1914d6487f797d9a7c3415b1 307 SUPERFAMILY SSF51735 1 301 1.52E-60 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11075 69ae91de1914d6487f797d9a7c3415b1 307 Gene3D G3DSA:3.40.50.720 2 179 7.7E-16 T 29-03-2018 CSW12_RS11075 69ae91de1914d6487f797d9a7c3415b1 307 Gene3D G3DSA:3.90.25.10 180 307 2.7E-30 T 29-03-2018 CSW12_RS11075 69ae91de1914d6487f797d9a7c3415b1 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 226 1.7E-43 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 SMART SM00530 9 64 3.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 Gene3D G3DSA:1.10.260.40 1 78 1.6E-20 T 29-03-2018 CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 SUPERFAMILY SSF47413 3 72 3.1E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 SUPERFAMILY SSF51182 57 181 9.13E-24 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 Pfam PF01381 Helix-turn-helix 10 61 1.7E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 Gene3D G3DSA:2.60.120.10 79 181 9.5E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS18895 4327e049ca3d6db4e85f5fc7e65964f1 181 Pfam PF07883 Cupin domain 106 174 3.8E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 PIRSF PIRSF001338 1 161 1.3E-68 T 29-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 SMART SM01001 3 154 8.0E-106 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 157 2.0E-67 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.4 T 29-03-2018 IPR033747 Class I PurE CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 Gene3D G3DSA:3.40.50.7700 1 161 1.4E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 Pfam PF00731 AIR carboxylase 5 150 1.6E-66 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CSW12_RS00020 9b48c1801a1e0ab6e2c0615c698e6d22 161 SUPERFAMILY SSF52255 4 158 2.49E-68 T 29-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 342 36.258 T 29-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 122 1.2E-32 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 343 3.0E-143 T 29-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 141 328 7.3E-55 T 29-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 SUPERFAMILY SSF55347 131 329 5.79E-72 T 29-03-2018 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 Gene3D G3DSA:3.40.50.720 2 142 2.3E-32 T 29-03-2018 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 239 253 - T 29-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 SUPERFAMILY SSF51735 6 158 2.55E-46 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 SMART SM00859 7 123 1.0E-39 T 29-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 Gene3D G3DSA:3.30.360.10 143 325 1.5E-67 T 29-03-2018 CSW12_RS15910 77d2d7bc1cc7a717bd346f8ec2dc0d4a 347 PIRSF PIRSF000148 5 347 4.4E-122 T 29-03-2018 CSW12_RS05575 2a5d516ece77cbe90a9341f435f15b4b 250 SUPERFAMILY SSF53335 28 234 1.41E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS05575 2a5d516ece77cbe90a9341f435f15b4b 250 Gene3D G3DSA:3.40.50.150 23 248 1.9E-26 T 29-03-2018 CSW12_RS05575 2a5d516ece77cbe90a9341f435f15b4b 250 Pfam PF08241 Methyltransferase domain 48 163 1.3E-19 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS30975 6c3678e75b327b1ad25c24ba3fe000a9 646 SUPERFAMILY SSF52540 212 626 7.59E-30 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30975 6c3678e75b327b1ad25c24ba3fe000a9 646 Gene3D G3DSA:3.40.50.300 7 608 1.0E-19 T 29-03-2018 CSW12_RS27580 7aee6e6677421f0c25cfd7f0d2d4fac4 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 1.1E-55 T 29-03-2018 IPR006056 RidA family CSW12_RS27580 7aee6e6677421f0c25cfd7f0d2d4fac4 124 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 29-03-2018 IPR019897 RidA, conserved site CSW12_RS27580 7aee6e6677421f0c25cfd7f0d2d4fac4 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 1.6E-47 T 29-03-2018 IPR006175 YjgF/YER057c/UK114 family CSW12_RS27580 7aee6e6677421f0c25cfd7f0d2d4fac4 124 SUPERFAMILY SSF55298 2 123 8.95E-48 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CSW12_RS27580 7aee6e6677421f0c25cfd7f0d2d4fac4 124 Gene3D G3DSA:3.30.1330.40 1 124 7.5E-48 T 29-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CSW12_RS02360 afa62e638f0b0b8b5297593a78bdaaa6 406 Gene3D G3DSA:1.10.260.40 23 145 2.2E-5 T 29-03-2018 CSW12_RS11650 2f09f02f62aec9019851d0d260fb4160 354 Pfam PF02687 FtsX-like permease family 261 344 3.4E-6 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS02545 ca215557bffe7951e4d962647b44f564 272 Pfam PF01183 Glycosyl hydrolases family 25 5 168 4.4E-27 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CSW12_RS02545 ca215557bffe7951e4d962647b44f564 272 Pfam PF12123 N-acetylmuramoyl-l-alanine amidase 225 269 4.4E-17 T 29-03-2018 IPR021976 N-acetylmuramoyl-l-alanine amidase CSW12_RS02545 ca215557bffe7951e4d962647b44f564 272 SUPERFAMILY SSF51445 3 188 5.79E-46 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS02545 ca215557bffe7951e4d962647b44f564 272 Gene3D G3DSA:3.20.20.80 1 189 1.2E-49 T 29-03-2018 CSW12_RS09590 bec123caa4354be135da2e24ad4ce68c 67 Gene3D G3DSA:2.20.25.10 4 64 6.1E-6 T 29-03-2018 CSW12_RS11385 9a60549567d4e04405d545debc3eb0bc 633 Pfam PF14478 Domain of unknown function (DUF4430) 60 129 3.7E-16 T 29-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CSW12_RS11385 9a60549567d4e04405d545debc3eb0bc 633 SUPERFAMILY SSF48239 346 521 5.02E-27 T 29-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CSW12_RS11385 9a60549567d4e04405d545debc3eb0bc 633 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 599 631 3.8E-4 T 29-03-2018 CSW12_RS11385 9a60549567d4e04405d545debc3eb0bc 633 Gene3D G3DSA:1.50.10.20 217 539 9.4E-32 T 29-03-2018 CSW12_RS09690 7c7b6fa103dbcaafae997703570a981c 191 SUPERFAMILY SSF52833 47 190 1.66E-46 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS09690 7c7b6fa103dbcaafae997703570a981c 191 Gene3D G3DSA:3.40.30.10 34 191 2.7E-44 T 29-03-2018 CSW12_RS09690 7c7b6fa103dbcaafae997703570a981c 191 ProSitePatterns PS00194 Thioredoxin family active site. 80 98 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CSW12_RS09690 7c7b6fa103dbcaafae997703570a981c 191 Pfam PF00578 AhpC/TSA family 52 172 1.1E-34 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS26465 4c0a6eaf627705fd638995a447a6ab9d 429 Gene3D G3DSA:3.65.10.10 219 419 2.1E-48 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS26465 4c0a6eaf627705fd638995a447a6ab9d 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 3.4E-92 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS26465 4c0a6eaf627705fd638995a447a6ab9d 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.1E-170 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS26465 4c0a6eaf627705fd638995a447a6ab9d 429 SUPERFAMILY SSF55205 1 416 2.29E-134 T 29-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CSW12_RS26465 4c0a6eaf627705fd638995a447a6ab9d 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.428 T 29-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS26465 4c0a6eaf627705fd638995a447a6ab9d 429 Gene3D G3DSA:3.65.10.10 21 218 2.3E-43 T 29-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CSW12_RS27950 65c80c55c3de5ebd444ec0d23952daad 82 Gene3D G3DSA:3.30.1330.30 2 82 4.4E-13 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS27950 65c80c55c3de5ebd444ec0d23952daad 82 SUPERFAMILY SSF55315 4 81 1.38E-16 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS27950 65c80c55c3de5ebd444ec0d23952daad 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 81 5.6E-12 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 48.476 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 SUPERFAMILY SSF56042 168 338 1.94E-58 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 SUPERFAMILY SSF55326 3 167 9.87E-53 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 333 8.0E-144 T 29-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 338 1.7E-38 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 161 2.0E-18 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 Gene3D G3DSA:3.30.1330.10 28 158 6.0E-57 T 29-03-2018 IPR016188 PurM-like, N-terminal domain CSW12_RS00060 a7188534311a2a16d5836f95b425e98b 346 Gene3D G3DSA:3.90.650.10 168 341 1.2E-62 T 29-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 Gene3D G3DSA:1.10.287.130 151 223 1.4E-17 T 29-03-2018 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 SUPERFAMILY SSF47384 145 227 4.12E-19 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 SUPERFAMILY SSF55874 216 380 4.19E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 1.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 363 1.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 338 1.2E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 Gene3D G3DSA:3.30.565.10 232 383 4.8E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 SMART SM00387 273 384 3.5E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 Pfam PF00512 His Kinase A (phospho-acceptor) domain 160 225 6.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 SMART SM00388 160 227 9.5E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS14955 c2e94bfe9b0978283b88a0b517daa895 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 381 3.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 SMART SM00857 2 136 7.3E-48 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 Gene3D G3DSA:3.40.50.1390 2 104 2.3E-29 T 29-03-2018 CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 Gene3D G3DSA:1.20.5.40 105 130 3.3E-16 T 29-03-2018 CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 SUPERFAMILY SSF53041 2 135 4.58E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 Gene3D G3DSA:1.10.10.60 131 181 1.2E-10 T 29-03-2018 CSW12_RS31190 822df1aedcd598dcf6c046e7db70729d 185 Pfam PF00239 Resolvase, N terminal domain 3 136 4.4E-41 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS00355 c37e20a13a6fd24f6009abdee5008eb9 803 Gene3D G3DSA:1.10.10.10 661 794 1.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00355 c37e20a13a6fd24f6009abdee5008eb9 803 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 27 347 4.8E-48 T 29-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CSW12_RS00355 c37e20a13a6fd24f6009abdee5008eb9 803 Pfam PF06605 Prophage endopeptidase tail 80 357 5.7E-16 T 29-03-2018 IPR010572 Prophage tail endopeptidase CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 SMART SM00387 314 426 1.0E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 Gene3D G3DSA:3.30.565.10 208 431 3.9E-25 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 SUPERFAMILY SSF55874 281 423 1.18E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 425 9.6E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 379 5.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 5.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 365 5.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS18805 f14be17c18da371ce2f366f1ac0785e9 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 5.9E-9 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 SUPERFAMILY SSF53955 55 262 1.07E-72 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 Pfam PF00905 Penicillin binding protein transpeptidase domain 336 613 8.7E-38 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 78 617 2.5E-184 T 29-03-2018 CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 Gene3D G3DSA:3.40.710.10 260 670 1.4E-102 T 29-03-2018 CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 SUPERFAMILY SSF56601 274 627 6.61E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 SUPERFAMILY SSF56601 222 244 6.61E-111 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 Gene3D G3DSA:1.10.3810.10 58 257 3.3E-74 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS06865 54695c201891be95198bdcc74c69c6ce 680 Pfam PF00912 Transglycosylase 69 240 9.6E-61 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS05815 362e3a7255619dd98b4f79d0bb4c61fd 196 Gene3D G3DSA:3.40.50.150 24 187 9.2E-25 T 29-03-2018 CSW12_RS05815 362e3a7255619dd98b4f79d0bb4c61fd 196 Pfam PF08241 Methyltransferase domain 50 148 2.2E-18 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS05815 362e3a7255619dd98b4f79d0bb4c61fd 196 SUPERFAMILY SSF53335 26 185 3.0E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS03380 f213840895f98dac8926be2b7abf202e 137 SUPERFAMILY SSF54593 24 135 1.11E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS03380 f213840895f98dac8926be2b7abf202e 137 Gene3D G3DSA:3.10.180.10 20 137 5.1E-12 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS27265 07ca46b881b089c308bb13184c2821e3 253 Gene3D G3DSA:3.40.50.300 1 252 4.5E-65 T 29-03-2018 CSW12_RS27265 07ca46b881b089c308bb13184c2821e3 253 SUPERFAMILY SSF52540 1 250 1.87E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27265 07ca46b881b089c308bb13184c2821e3 253 PIRSF PIRSF009320 54 251 7.2E-9 T 29-03-2018 CSW12_RS27265 07ca46b881b089c308bb13184c2821e3 253 PIRSF PIRSF009320 2 87 1.0E-14 T 29-03-2018 CSW12_RS27265 07ca46b881b089c308bb13184c2821e3 253 Pfam PF13614 AAA domain 2 178 1.0E-74 T 29-03-2018 IPR025669 AAA domain CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 PIRSF PIRSF002808 6 444 6.1E-125 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 Gene3D G3DSA:1.20.1250.20 18 218 5.6E-35 T 29-03-2018 CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 ProSitePatterns PS00942 glpT family of transporters signature. 150 166 - T 29-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 SUPERFAMILY SSF103473 13 433 2.09E-78 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 Gene3D G3DSA:1.20.1250.20 240 442 2.1E-31 T 29-03-2018 CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 36 415 2.2E-127 T 29-03-2018 CSW12_RS26055 1980a1dd883897e53d9089b46fc1e3e2 444 Pfam PF07690 Major Facilitator Superfamily 35 397 5.0E-47 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 SUPERFAMILY SSF51735 281 571 3.74E-98 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 Pfam PF00390 Malic enzyme, N-terminal domain 89 271 2.4E-73 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 Gene3D G3DSA:3.40.50.10380 23 278 1.3E-107 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 193 215 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 277 293 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 417 433 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 157 186 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 95 119 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 308 324 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PRINTS PR00072 Malic enzyme signature 252 270 3.9E-71 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 SMART SM00919 281 539 2.8E-130 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 Gene3D G3DSA:3.40.50.720 279 577 1.2E-113 T 29-03-2018 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 SMART SM01274 89 271 3.8E-99 T 29-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 SUPERFAMILY SSF53223 8 280 3.81E-107 T 29-03-2018 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 ProSitePatterns PS00331 Malic enzymes signature. 277 293 - T 29-03-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 Pfam PF03949 Malic enzyme, NAD binding domain 281 538 2.3E-108 T 29-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CSW12_RS18810 bb1360d97df99bda43c8b7be68abb72d 577 PIRSF PIRSF000106 3 572 1.8E-231 T 29-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CSW12_RS05690 b4306c73f2d5b2b555f7c2f9e2c31a1d 190 Pfam PF00027 Cyclic nucleotide-binding domain 30 105 1.1E-8 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS05690 b4306c73f2d5b2b555f7c2f9e2c31a1d 190 Gene3D G3DSA:2.60.120.10 7 133 4.2E-18 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS05690 b4306c73f2d5b2b555f7c2f9e2c31a1d 190 SMART SM00100 11 130 0.0016 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS05690 b4306c73f2d5b2b555f7c2f9e2c31a1d 190 SUPERFAMILY SSF51206 16 132 5.89E-20 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS05690 b4306c73f2d5b2b555f7c2f9e2c31a1d 190 Gene3D G3DSA:1.10.10.10 134 190 2.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15815 62cdcecac166208c344e9e632016e48a 415 Gene3D G3DSA:1.25.10.10 24 149 5.7E-6 T 29-03-2018 IPR011989 Armadillo-like helical CSW12_RS15815 62cdcecac166208c344e9e632016e48a 415 SUPERFAMILY SSF48371 38 143 1.57E-6 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS15815 62cdcecac166208c344e9e632016e48a 415 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 252 415 4.4E-65 T 29-03-2018 IPR021210 Exosporium BclB, C-terminal CSW12_RS15815 62cdcecac166208c344e9e632016e48a 415 Gene3D G3DSA:2.160.20.50 202 255 1.3E-16 T 29-03-2018 CSW12_RS15815 62cdcecac166208c344e9e632016e48a 415 Gene3D G3DSA:2.160.20.50 150 201 4.1E-12 T 29-03-2018 CSW12_RS15815 62cdcecac166208c344e9e632016e48a 415 Pfam PF01391 Collagen triple helix repeat (20 copies) 195 252 4.4E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 78.148 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 8 149 7.1E-62 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 2.0E-60 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 Gene3D G3DSA:2.40.280.10 9 127 5.9E-54 T 29-03-2018 IPR023620 Small protein B CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 SUPERFAMILY SSF74982 4 132 4.45E-55 T 29-03-2018 IPR023620 Small protein B CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 29-03-2018 IPR020081 SsrA-binding protein, conserved site CSW12_RS25305 0315ade4a361f824ac72c94765610b97 155 Pfam PF01668 SmpB protein 9 150 1.6E-64 T 29-03-2018 IPR000037 SsrA-binding protein GO:0003723 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00412 Epoxide hydrolase signature 49 64 3.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00412 Epoxide hydrolase signature 211 227 3.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00412 Epoxide hydrolase signature 244 266 3.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00412 Epoxide hydrolase signature 29 47 3.7E-9 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 Gene3D G3DSA:3.40.50.1820 4 269 1.5E-48 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 6.8E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 6.8E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 6.8E-10 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 Pfam PF00561 alpha/beta hydrolase fold 24 251 2.6E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS23610 720facb16a26536ce858bac76993654c 269 SUPERFAMILY SSF53474 2 268 4.31E-58 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS23155 8bc51fd864537b114efe4b997691d982 169 Gene3D G3DSA:3.90.950.10 1 166 5.8E-50 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CSW12_RS23155 8bc51fd864537b114efe4b997691d982 169 Pfam PF01931 Protein of unknown function DUF84 6 156 1.0E-44 T 29-03-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 CSW12_RS23155 8bc51fd864537b114efe4b997691d982 169 SUPERFAMILY SSF52972 1 165 4.8E-48 T 29-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CSW12_RS16545 d262c6ca968a71b5ab2fa7e1f33d54fd 198 Gene3D G3DSA:3.40.630.30 4 182 4.8E-11 T 29-03-2018 CSW12_RS16545 d262c6ca968a71b5ab2fa7e1f33d54fd 198 SUPERFAMILY SSF55729 33 150 3.01E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06370 87c78af31ca93d0c4598ff309b9dc8dd 137 SUPERFAMILY SSF69118 15 137 3.04E-21 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS06370 87c78af31ca93d0c4598ff309b9dc8dd 137 Gene3D G3DSA:1.20.1290.10 71 137 3.4E-7 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS06370 87c78af31ca93d0c4598ff309b9dc8dd 137 Gene3D G3DSA:1.20.1290.10 6 66 2.3E-5 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS13070 a5eda0a1a7ad4920320b04cd54fbf627 328 Gene3D G3DSA:3.40.190.10 139 325 8.7E-41 T 29-03-2018 CSW12_RS13070 a5eda0a1a7ad4920320b04cd54fbf627 328 SMART SM00062 34 256 9.4E-26 T 29-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CSW12_RS13070 a5eda0a1a7ad4920320b04cd54fbf627 328 SUPERFAMILY SSF53850 31 258 8.28E-52 T 29-03-2018 CSW12_RS13070 a5eda0a1a7ad4920320b04cd54fbf627 328 Gene3D G3DSA:3.40.190.10 30 138 1.6E-16 T 29-03-2018 CSW12_RS13070 a5eda0a1a7ad4920320b04cd54fbf627 328 Pfam PF09084 NMT1/THI5 like 44 248 1.2E-28 T 29-03-2018 IPR015168 SsuA/THI5-like CSW12_RS13070 a5eda0a1a7ad4920320b04cd54fbf627 328 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 35 321 1.4E-92 T 29-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CSW12_RS27130 9b78159abdf52e7abb8444ef36062568 292 Gene3D G3DSA:3.20.20.70 126 289 2.5E-5 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS27130 9b78159abdf52e7abb8444ef36062568 292 Gene3D G3DSA:3.20.20.70 2 125 4.3E-21 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS27130 9b78159abdf52e7abb8444ef36062568 292 Pfam PF13394 4Fe-4S single cluster domain 12 89 3.5E-5 T 29-03-2018 CSW12_RS27130 9b78159abdf52e7abb8444ef36062568 292 Pfam PF13186 Iron-sulfur cluster-binding domain 219 284 4.4E-12 T 29-03-2018 IPR023885 4Fe4S-binding SPASM domain CSW12_RS27130 9b78159abdf52e7abb8444ef36062568 292 SUPERFAMILY SSF102114 7 287 8.11E-36 T 29-03-2018 CSW12_RS27130 9b78159abdf52e7abb8444ef36062568 292 Pfam PF04055 Radical SAM superfamily 10 113 6.0E-13 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS08760 acb652d328da14c08a9f41e9502a5a17 83 SUPERFAMILY SSF50346 1 77 8.63E-12 T 29-03-2018 IPR011033 PRC-barrel-like CSW12_RS08760 acb652d328da14c08a9f41e9502a5a17 83 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 75 1.6E-28 T 29-03-2018 IPR014238 Sporulation protein YlmC/YmxH CSW12_RS08760 acb652d328da14c08a9f41e9502a5a17 83 Gene3D G3DSA:2.30.30.240 1 79 5.8E-14 T 29-03-2018 CSW12_RS08760 acb652d328da14c08a9f41e9502a5a17 83 Pfam PF05239 PRC-barrel domain 1 77 2.6E-13 T 29-03-2018 IPR027275 PRC-barrel domain CSW12_RS00850 78052a173178679b747ae11377f78294 193 SUPERFAMILY SSF46689 1 72 2.26E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS00850 78052a173178679b747ae11377f78294 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS00850 78052a173178679b747ae11377f78294 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS00850 78052a173178679b747ae11377f78294 193 Gene3D G3DSA:1.10.10.60 1 43 6.0E-14 T 29-03-2018 CSW12_RS00850 78052a173178679b747ae11377f78294 193 Pfam PF08360 QacR-like protein, C-terminal region 62 192 2.9E-60 T 29-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 CSW12_RS00850 78052a173178679b747ae11377f78294 193 SUPERFAMILY SSF48498 78 191 8.01E-39 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS00850 78052a173178679b747ae11377f78294 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 56 1.8E-15 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS00850 78052a173178679b747ae11377f78294 193 Gene3D G3DSA:1.10.357.10 69 193 1.9E-15 T 29-03-2018 CSW12_RS00850 78052a173178679b747ae11377f78294 193 Gene3D G3DSA:1.10.10.60 44 68 2.7E-10 T 29-03-2018 CSW12_RS06230 438c4669b8311d6b0485155a24051659 564 TIGRFAM TIGR02289 M3_not_pepF: oligoendopeptidase, M3 family 13 560 8.7E-253 T 29-03-2018 IPR011976 Peptidase M3B, oligoendopeptidase-related CSW12_RS06230 438c4669b8311d6b0485155a24051659 564 SUPERFAMILY SSF55486 33 558 1.95E-124 T 29-03-2018 CSW12_RS06230 438c4669b8311d6b0485155a24051659 564 Gene3D G3DSA:1.10.1370.10 68 553 6.0E-59 T 29-03-2018 CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 Gene3D G3DSA:3.40.50.2300 1 122 2.6E-27 T 29-03-2018 CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 Gene3D G3DSA:1.10.10.10 123 231 1.7E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 Pfam PF00072 Response regulator receiver domain 5 115 1.0E-22 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 SMART SM00862 149 226 2.6E-16 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 SMART SM00448 3 114 5.8E-34 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 SUPERFAMILY SSF52172 4 120 3.7E-34 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 SUPERFAMILY SSF46894 125 227 7.65E-23 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS12380 a5e54008afad468b9ea4e6da187c8331 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 7.9E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS16150 c46cb8d81a1ca9039b03a635a2505c94 180 SUPERFAMILY SSF64288 19 173 7.06E-27 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS16150 c46cb8d81a1ca9039b03a635a2505c94 180 Gene3D G3DSA:3.40.1410.10 14 180 3.9E-12 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS29195 4fabf38be2f18730146cf6011337a71c 860 PIRSF PIRSF015040 5 860 1.6E-113 T 29-03-2018 IPR016628 ATPase, SAG2001, predicted CSW12_RS29195 4fabf38be2f18730146cf6011337a71c 860 SUPERFAMILY SSF52540 440 830 3.43E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS29195 4fabf38be2f18730146cf6011337a71c 860 Pfam PF12846 AAA-like domain 470 845 5.5E-75 T 29-03-2018 CSW12_RS29195 4fabf38be2f18730146cf6011337a71c 860 Gene3D G3DSA:3.40.50.300 266 822 1.1E-14 T 29-03-2018 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 SUPERFAMILY SSF56645 2 242 1.83E-97 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 SUPERFAMILY SSF47203 227 378 1.56E-60 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.5E-28 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 Gene3D G3DSA:1.10.540.10 1 120 5.3E-46 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 3.8E-53 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 Gene3D G3DSA:2.40.110.10 121 217 2.6E-40 T 29-03-2018 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 PIRSF PIRSF016578 3 377 1.1E-20 T 29-03-2018 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.2E-44 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS26500 df7c9364a2afa32c98e8c5c401cb3c8c 379 Gene3D G3DSA:1.20.140.10 218 379 2.4E-66 T 29-03-2018 CSW12_RS04790 9168178759e46b167f5e66d1cca3361e 285 SUPERFAMILY SSF161098 23 273 2.49E-56 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS04790 9168178759e46b167f5e66d1cca3361e 285 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 19 280 1.3E-97 T 29-03-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CSW12_RS04790 9168178759e46b167f5e66d1cca3361e 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 277 2.0E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS04790 9168178759e46b167f5e66d1cca3361e 285 Gene3D G3DSA:1.10.3720.10 25 285 6.1E-45 T 29-03-2018 CSW12_RS04790 9168178759e46b167f5e66d1cca3361e 285 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 26 282 2.3E-121 T 29-03-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CSW12_RS02585 2f84236af1d9f5079fb300c2f77ff3fa 390 Pfam PF01168 Alanine racemase, N-terminal domain 17 262 1.5E-9 T 29-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CSW12_RS02585 2f84236af1d9f5079fb300c2f77ff3fa 390 Gene3D G3DSA:3.20.20.10 19 269 2.4E-31 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS02585 2f84236af1d9f5079fb300c2f77ff3fa 390 SUPERFAMILY SSF51419 20 262 4.09E-18 T 29-03-2018 IPR029066 PLP-binding barrel CSW12_RS18560 972e6a92f7af1815f94a10b0b6706089 307 Pfam PF12146 Serine aminopeptidase, S33 26 289 6.2E-52 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS18560 972e6a92f7af1815f94a10b0b6706089 307 Gene3D G3DSA:3.40.50.1820 1 307 5.2E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS18560 972e6a92f7af1815f94a10b0b6706089 307 SUPERFAMILY SSF53474 2 305 3.62E-39 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS24660 d4d3259f018cf3e1e03150d31f38350b 184 SUPERFAMILY SSF53254 1 175 7.26E-30 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS24660 d4d3259f018cf3e1e03150d31f38350b 184 SMART SM00855 3 143 2.8E-4 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS24660 d4d3259f018cf3e1e03150d31f38350b 184 Gene3D G3DSA:3.40.50.1240 1 184 4.6E-27 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS24660 d4d3259f018cf3e1e03150d31f38350b 184 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 173 2.6E-21 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 ProSitePatterns PS00818 Dps protein family signature 1. 29 45 - T 29-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 Gene3D G3DSA:1.20.1260.10 1 147 8.6E-52 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 124 142 1.5E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 29 45 1.5E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 53 69 1.5E-13 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 SUPERFAMILY SSF47240 7 146 7.65E-49 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 PIRSF PIRSF005900 1 147 1.1E-51 T 29-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CSW12_RS17790 4be2d6967fab385b7d5f3ba114d44176 147 Pfam PF00210 Ferritin-like domain 9 146 5.1E-36 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CSW12_RS10760 c2a585e7a5d138987e783eae84fd0430 159 SMART SM00871 2 157 5.0E-4 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS10760 c2a585e7a5d138987e783eae84fd0430 159 Gene3D G3DSA:3.20.80.10 1 156 2.6E-16 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS10760 c2a585e7a5d138987e783eae84fd0430 159 Pfam PF14526 Integron-associated effector binding protein 5 156 9.9E-30 T 29-03-2018 IPR029441 Integron-associated effector binding protein CSW12_RS15900 442c68f58a4c32966598aef2dffcfc5a 375 SUPERFAMILY SSF56235 108 231 1.7E-5 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS15900 442c68f58a4c32966598aef2dffcfc5a 375 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 108 332 4.1E-69 T 29-03-2018 IPR005079 Peptidase C45 CSW12_RS15900 442c68f58a4c32966598aef2dffcfc5a 375 Gene3D G3DSA:3.60.60.10 91 342 2.4E-29 T 29-03-2018 CSW12_RS23565 6f88c87d5a7bcb575f30dd157ea7150a 365 Gene3D G3DSA:2.160.20.50 125 164 9.7E-14 T 29-03-2018 CSW12_RS23565 6f88c87d5a7bcb575f30dd157ea7150a 365 Gene3D G3DSA:2.160.20.50 4 81 5.6E-13 T 29-03-2018 CSW12_RS23565 6f88c87d5a7bcb575f30dd157ea7150a 365 Gene3D G3DSA:2.160.20.50 165 211 1.9E-14 T 29-03-2018 CSW12_RS23565 6f88c87d5a7bcb575f30dd157ea7150a 365 Pfam PF01391 Collagen triple helix repeat (20 copies) 151 204 2.2E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23565 6f88c87d5a7bcb575f30dd157ea7150a 365 Pfam PF01391 Collagen triple helix repeat (20 copies) 127 181 3.2E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23565 6f88c87d5a7bcb575f30dd157ea7150a 365 Pfam PF01391 Collagen triple helix repeat (20 copies) 16 74 4.0E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS07025 b18c6b7b9dd909d076efc71a4843240a 159 SUPERFAMILY SSF54106 102 149 2.22E-8 T 29-03-2018 IPR018392 LysM domain CSW12_RS07025 b18c6b7b9dd909d076efc71a4843240a 159 Pfam PF01476 LysM domain 104 149 1.6E-11 T 29-03-2018 IPR018392 LysM domain CSW12_RS07025 b18c6b7b9dd909d076efc71a4843240a 159 Gene3D G3DSA:3.10.350.10 96 159 1.4E-13 T 29-03-2018 CSW12_RS07025 b18c6b7b9dd909d076efc71a4843240a 159 SMART SM00257 103 149 5.0E-12 T 29-03-2018 IPR018392 LysM domain CSW12_RS04485 8fe1b30017c4513c71606f28cdb96bfc 135 Pfam PF03551 Transcriptional regulator PadR-like family 48 116 2.5E-14 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS04485 8fe1b30017c4513c71606f28cdb96bfc 135 SUPERFAMILY SSF46785 44 123 1.84E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04485 8fe1b30017c4513c71606f28cdb96bfc 135 Gene3D G3DSA:1.10.10.10 24 135 2.1E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20530 143e400c96f9b0f6c31cc3cc9465f809 210 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 2 111 1.7E-36 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CSW12_RS20530 143e400c96f9b0f6c31cc3cc9465f809 210 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 199 3.8E-34 T 29-03-2018 IPR014245 Sporulation stage III, protein AF CSW12_RS06185 bda8799286885667db29b76fa996999b 260 Gene3D G3DSA:1.10.10.10 4 78 1.9E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06185 bda8799286885667db29b76fa996999b 260 SMART SM01134 75 241 1.3E-56 T 29-03-2018 CSW12_RS06185 bda8799286885667db29b76fa996999b 260 Pfam PF00455 DeoR C terminal sensor domain 77 240 4.2E-43 T 29-03-2018 IPR014036 DeoR C-terminal sensor domain CSW12_RS06185 bda8799286885667db29b76fa996999b 260 SUPERFAMILY SSF100950 75 241 6.51E-32 T 29-03-2018 CSW12_RS06185 bda8799286885667db29b76fa996999b 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 40 58 1.6E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS06185 bda8799286885667db29b76fa996999b 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 26 40 1.6E-5 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS06185 bda8799286885667db29b76fa996999b 260 SUPERFAMILY SSF46785 6 62 3.24E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06185 bda8799286885667db29b76fa996999b 260 Pfam PF08220 DeoR-like helix-turn-helix domain 8 59 3.9E-12 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS06185 bda8799286885667db29b76fa996999b 260 Gene3D G3DSA:3.40.50.1360 79 243 6.9E-35 T 29-03-2018 CSW12_RS06185 bda8799286885667db29b76fa996999b 260 SMART SM00420 8 60 4.6E-11 T 29-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 SUPERFAMILY SSF53041 11 159 1.22E-34 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 SMART SM00857 11 159 1.1E-37 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 ProSitePatterns PS00397 Site-specific recombinases active site. 14 22 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 Pfam PF00239 Resolvase, N terminal domain 12 159 1.6E-30 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 Gene3D G3DSA:3.40.50.1390 10 127 8.4E-27 T 29-03-2018 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 ProSitePatterns PS00398 Site-specific recombinases signature 2. 66 78 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30160 aba0f9a6e118ca83240c799b4fcd417b 219 Gene3D G3DSA:1.20.5.40 128 157 4.0E-13 T 29-03-2018 CSW12_RS24560 8f0cfd2c1bc216142e518bd1df0b5dd4 333 SUPERFAMILY SSF56112 4 314 4.9E-16 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS24560 8f0cfd2c1bc216142e518bd1df0b5dd4 333 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 3 313 7.5E-112 T 29-03-2018 IPR014254 Spore coat protein YutH CSW12_RS24560 8f0cfd2c1bc216142e518bd1df0b5dd4 333 Gene3D G3DSA:3.90.1200.10 192 314 6.6E-7 T 29-03-2018 CSW12_RS24560 8f0cfd2c1bc216142e518bd1df0b5dd4 333 Gene3D G3DSA:3.90.1200.10 89 191 1.3E-6 T 29-03-2018 CSW12_RS07180 3941acf77a338f2f82278b3f30e3500c 174 SUPERFAMILY SSF81301 5 169 3.01E-52 T 29-03-2018 CSW12_RS07180 3941acf77a338f2f82278b3f30e3500c 174 Pfam PF04229 GrpB protein 4 162 1.0E-53 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CSW12_RS07180 3941acf77a338f2f82278b3f30e3500c 174 Gene3D G3DSA:3.30.460.10 1 170 2.2E-57 T 29-03-2018 CSW12_RS27275 a94fb26d12eb5e254ef49954b3171ff9 239 SUPERFAMILY SSF53335 1 237 2.43E-49 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS27275 a94fb26d12eb5e254ef49954b3171ff9 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.374 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CSW12_RS27275 a94fb26d12eb5e254ef49954b3171ff9 239 Gene3D G3DSA:3.40.50.150 1 238 1.0E-40 T 29-03-2018 CSW12_RS27275 a94fb26d12eb5e254ef49954b3171ff9 239 Pfam PF02527 rRNA small subunit methyltransferase G 21 203 9.7E-58 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CSW12_RS27275 a94fb26d12eb5e254ef49954b3171ff9 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 216 7.3E-52 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CSW12_RS27275 a94fb26d12eb5e254ef49954b3171ff9 239 PIRSF PIRSF003078 1 220 9.3E-60 T 29-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CSW12_RS12300 a5274a7b5bb69ebcc53ae751697525a3 329 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 300 5.3E-87 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CSW12_RS12300 a5274a7b5bb69ebcc53ae751697525a3 329 SMART SM00797 24 317 1.3E-135 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CSW12_RS12300 a5274a7b5bb69ebcc53ae751697525a3 329 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 324 8.3E-93 T 29-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CSW12_RS12300 a5274a7b5bb69ebcc53ae751697525a3 329 SUPERFAMILY SSF50891 193 307 3.22E-12 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 68.219 T 29-03-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 SUPERFAMILY SSF53383 3 395 4.59E-125 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 Gene3D G3DSA:3.90.1150.10 3 164 1.8E-40 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 PIRSF PIRSF000521 2 160 2.0E-8 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 PIRSF PIRSF000521 175 396 2.6E-31 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 395 1.1E-164 T 29-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 Gene3D G3DSA:3.40.640.10 172 293 9.3E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 Gene3D G3DSA:3.90.1150.10 294 396 2.2E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS05025 724e494bb884b495b2a23757432631ee 396 Pfam PF00202 Aminotransferase class-III 15 395 1.5E-133 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS26090 82fd486376b7b5f7641af074b0a116cb 304 Hamap MF_01140 Transcriptional regulator LytR [lytR]. 2 302 51.104 T 29-03-2018 IPR023734 Transcriptional regulator, LytR GO:0010468 CSW12_RS26090 82fd486376b7b5f7641af074b0a116cb 304 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 78 219 1.5E-49 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS26090 82fd486376b7b5f7641af074b0a116cb 304 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 77 220 6.4E-52 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS10400 39fa298daad0620b26c637b49c30db9e 488 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 474 46.661 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CSW12_RS10400 39fa298daad0620b26c637b49c30db9e 488 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 12 458 5.4E-123 T 29-03-2018 IPR003846 Uncharacterised protein family UPF0061 CSW12_RS18100 804bc4f08f85c222f5dcdd706cd20162 333 PIRSF PIRSF028757 1 333 4.7E-86 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS18100 804bc4f08f85c222f5dcdd706cd20162 333 SUPERFAMILY SSF52317 1 160 5.04E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS18100 804bc4f08f85c222f5dcdd706cd20162 333 Gene3D G3DSA:3.40.50.10740 1 163 1.2E-45 T 29-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CSW12_RS18100 804bc4f08f85c222f5dcdd706cd20162 333 SUPERFAMILY SSF141986 176 325 1.1E-41 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS18100 804bc4f08f85c222f5dcdd706cd20162 333 Pfam PF02016 LD-carboxypeptidase 13 317 4.2E-70 T 29-03-2018 IPR003507 Peptidase family S66 CSW12_RS18100 804bc4f08f85c222f5dcdd706cd20162 333 Gene3D G3DSA:3.50.30.60 165 333 1.3E-45 T 29-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 SUPERFAMILY SSF51735 3 148 5.15E-41 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 5 380 46.785 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 379 1.8E-160 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 SUPERFAMILY SSF55347 124 262 5.56E-58 T 29-03-2018 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 130 3.9E-43 T 29-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 Gene3D G3DSA:3.40.50.720 2 148 4.8E-49 T 29-03-2018 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 375 2.5E-41 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 SUPERFAMILY SSF69055 289 381 7.72E-33 T 29-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 8.5E-39 T 29-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 PIRSF PIRSF006205 2 385 1.1E-162 T 29-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CSW12_RS11180 c77ab8513045dc2fa3b3538d5d97dd39 385 Gene3D G3DSA:1.10.1740.10 301 385 2.0E-29 T 29-03-2018 CSW12_RS16900 b32c7c271a121dd470eb72ee696af5c2 144 Pfam PF00583 Acetyltransferase (GNAT) family 44 133 1.6E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS16900 b32c7c271a121dd470eb72ee696af5c2 144 Gene3D G3DSA:3.40.630.30 1 144 1.2E-20 T 29-03-2018 CSW12_RS16900 b32c7c271a121dd470eb72ee696af5c2 144 SUPERFAMILY SSF55729 3 139 4.32E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS25735 5482e288a82f485c86c069a9ba9681f0 357 ProSitePatterns PS01348 MraY family signature 2. 147 158 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS25735 5482e288a82f485c86c069a9ba9681f0 357 Pfam PF00953 Glycosyl transferase family 4 72 231 8.6E-39 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CSW12_RS09655 aad61f3d019d2addd30577d4a8b084eb 44 Pfam PF08179 Small acid-soluble spore protein P family 8 39 6.7E-16 T 29-03-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 CSW12_RS09655 aad61f3d019d2addd30577d4a8b084eb 44 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 44 15.796 T 29-03-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 392 9.9E-15 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 Gene3D G3DSA:3.40.1190.10 95 310 1.4E-53 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 454 32.511 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 SUPERFAMILY SSF63418 8 101 8.5E-20 T 29-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 451 4.2E-129 T 29-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 SUPERFAMILY SSF53623 104 310 1.57E-47 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 Pfam PF08245 Mur ligase middle domain 110 293 2.2E-44 T 29-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 Gene3D G3DSA:3.90.190.20 313 454 2.1E-42 T 29-03-2018 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 Gene3D G3DSA:3.40.1390.10 2 94 1.2E-21 T 29-03-2018 CSW12_RS17045 44afee9e1fa601ff54198e87a0d12890 454 SUPERFAMILY SSF53244 315 452 7.33E-35 T 29-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 Gene3D G3DSA:3.20.130.10 314 487 1.8E-63 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 PIRSF PIRSF001394 1 505 1.2E-199 T 29-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 280 2.4E-60 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 325 486 5.6E-51 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 SUPERFAMILY SSF117457 316 486 1.19E-52 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 Pfam PF05683 Fumarase C-terminus 289 488 7.4E-63 T 29-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CSW12_RS01020 c352409935aea603518ad0b29a018f8e 506 Pfam PF05681 Fumarate hydratase (Fumerase) 6 281 1.3E-70 T 29-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CSW12_RS27405 348d26bab666e1de7802113d68a745d7 222 SUPERFAMILY SSF52540 14 215 1.2E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27405 348d26bab666e1de7802113d68a745d7 222 Pfam PF01712 Deoxynucleoside kinase 15 214 1.8E-63 T 29-03-2018 IPR031314 Deoxynucleoside kinase domain CSW12_RS27405 348d26bab666e1de7802113d68a745d7 222 Gene3D G3DSA:3.40.50.300 10 216 6.0E-42 T 29-03-2018 CSW12_RS27405 348d26bab666e1de7802113d68a745d7 222 PIRSF PIRSF000705 2 220 1.6E-64 T 29-03-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 CSW12_RS07905 b04f7277115bc7ac04865e76460905bd 130 Gene3D G3DSA:3.30.310.120 51 127 7.5E-34 T 29-03-2018 CSW12_RS07905 b04f7277115bc7ac04865e76460905bd 130 SUPERFAMILY SSF111171 4 128 1.7E-64 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 CSW12_RS07905 b04f7277115bc7ac04865e76460905bd 130 Pfam PF08968 Domain of unknown function (DUF1885) 2 129 4.3E-57 T 29-03-2018 IPR015062 Protein of unknown function DUF1885 CSW12_RS07905 b04f7277115bc7ac04865e76460905bd 130 Gene3D G3DSA:1.20.5.850 3 49 3.2E-22 T 29-03-2018 CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 122 1.1E-34 T 29-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 SUPERFAMILY SSF54862 24 125 2.18E-24 T 29-03-2018 CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 Pfam PF12838 4Fe-4S dicluster domain 45 102 2.4E-10 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 Gene3D G3DSA:3.30.70.20 92 139 5.3E-6 T 29-03-2018 CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 Gene3D G3DSA:3.30.70.20 12 56 1.5E-6 T 29-03-2018 CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 Gene3D G3DSA:3.30.70.20 57 91 1.7E-10 T 29-03-2018 CSW12_RS26250 e2fd3e92a2b45763e92b539796052a99 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 29-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CSW12_RS25560 7fdb6591a6ae9cc46a281ceaf8e0e979 70 Pfam PF01381 Helix-turn-helix 12 66 1.3E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS25560 7fdb6591a6ae9cc46a281ceaf8e0e979 70 SMART SM00530 11 66 1.0E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS25560 7fdb6591a6ae9cc46a281ceaf8e0e979 70 Gene3D G3DSA:1.10.3100.10 6 70 1.4E-17 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS25560 7fdb6591a6ae9cc46a281ceaf8e0e979 70 SUPERFAMILY SSF47413 8 68 2.39E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS04130 bdab768c70c7291f3381b482982071d6 332 Pfam PF02733 Dak1 domain 18 328 4.1E-95 T 29-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CSW12_RS04130 bdab768c70c7291f3381b482982071d6 332 SUPERFAMILY SSF82549 1 332 1.05E-101 T 29-03-2018 CSW12_RS04130 bdab768c70c7291f3381b482982071d6 332 Gene3D G3DSA:3.30.1180.20 187 332 2.2E-36 T 29-03-2018 CSW12_RS04130 bdab768c70c7291f3381b482982071d6 332 Gene3D G3DSA:3.40.50.10440 11 186 1.4E-57 T 29-03-2018 CSW12_RS04130 bdab768c70c7291f3381b482982071d6 332 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 3 332 1.1E-131 T 29-03-2018 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b CSW12_RS05930 76c7e34cd3631cf265673c6e4a02dfd2 189 Pfam PF00717 Peptidase S24-like 47 104 3.1E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS05930 76c7e34cd3631cf265673c6e4a02dfd2 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 105 116 6.2E-7 T 29-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CSW12_RS05930 76c7e34cd3631cf265673c6e4a02dfd2 189 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 6.2E-7 T 29-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CSW12_RS05930 76c7e34cd3631cf265673c6e4a02dfd2 189 Gene3D G3DSA:2.10.109.10 41 137 6.1E-13 T 29-03-2018 CSW12_RS05930 76c7e34cd3631cf265673c6e4a02dfd2 189 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 6 167 2.7E-58 T 29-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CSW12_RS05930 76c7e34cd3631cf265673c6e4a02dfd2 189 SUPERFAMILY SSF51306 41 118 9.42E-11 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS04275 b40f9991360ea973f536dc23f2b81b0d 403 Gene3D G3DSA:1.10.1660.10 187 267 0.024 T 29-03-2018 CSW12_RS04275 b40f9991360ea973f536dc23f2b81b0d 403 Pfam PF08279 HTH domain 161 199 1.4E-4 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS04275 b40f9991360ea973f536dc23f2b81b0d 403 Pfam PF01610 Transposase 2 200 1.4E-11 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS04275 b40f9991360ea973f536dc23f2b81b0d 403 Pfam PF01610 Transposase 293 397 2.8E-13 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS04275 b40f9991360ea973f536dc23f2b81b0d 403 Gene3D G3DSA:1.10.10.60 90 138 1.9E-4 T 29-03-2018 CSW12_RS04275 b40f9991360ea973f536dc23f2b81b0d 403 Gene3D G3DSA:1.10.10.60 149 186 1.5E-9 T 29-03-2018 CSW12_RS23910 b40f9991360ea973f536dc23f2b81b0d 403 Gene3D G3DSA:1.10.1660.10 187 267 0.024 T 29-03-2018 CSW12_RS23910 b40f9991360ea973f536dc23f2b81b0d 403 Pfam PF08279 HTH domain 161 199 1.4E-4 T 29-03-2018 IPR013196 Helix-turn-helix, type 11 CSW12_RS23910 b40f9991360ea973f536dc23f2b81b0d 403 Pfam PF01610 Transposase 2 200 1.4E-11 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS23910 b40f9991360ea973f536dc23f2b81b0d 403 Pfam PF01610 Transposase 293 397 2.8E-13 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS23910 b40f9991360ea973f536dc23f2b81b0d 403 Gene3D G3DSA:1.10.10.60 90 138 1.9E-4 T 29-03-2018 CSW12_RS23910 b40f9991360ea973f536dc23f2b81b0d 403 Gene3D G3DSA:1.10.10.60 149 186 1.5E-9 T 29-03-2018 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 SMART SM00421 146 203 2.1E-29 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 SUPERFAMILY SSF52172 1 134 4.41E-32 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 Gene3D G3DSA:3.40.50.2300 1 133 2.2E-36 T 29-03-2018 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 5.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 5.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 5.1E-16 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 9.5E-23 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 Gene3D G3DSA:1.10.10.10 134 208 7.1E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 SMART SM00448 2 115 2.1E-24 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 Pfam PF00072 Response regulator receiver domain 4 115 1.0E-23 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS06780 f2d97f038977ca15864abecff923d17b 210 SUPERFAMILY SSF46894 138 208 9.52E-25 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 Gene3D G3DSA:2.40.50.140 17 87 2.4E-11 T 29-03-2018 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 Pfam PF03193 RsgA GTPase 86 261 1.1E-49 T 29-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 66 316 1.0E-49 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 SUPERFAMILY SSF50249 26 90 3.22E-8 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 Gene3D G3DSA:1.10.40.50 263 329 8.9E-20 T 29-03-2018 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 Gene3D G3DSA:3.40.50.300 100 260 2.0E-24 T 29-03-2018 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 24 324 33.059 T 29-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CSW12_RS17820 f28b5af010a5903c16baf7a50e901251 349 SUPERFAMILY SSF52540 103 322 8.08E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 Gene3D G3DSA:1.10.357.10 79 205 6.6E-13 T 29-03-2018 CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 SUPERFAMILY SSF46689 18 88 4.14E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 Gene3D G3DSA:1.10.260.40 45 78 3.0E-11 T 29-03-2018 CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 SUPERFAMILY SSF48498 92 203 6.52E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 Gene3D G3DSA:1.10.10.60 9 44 1.4E-11 T 29-03-2018 CSW12_RS26495 8873af75f31c1f23931f200a4e844634 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 6.4E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS14905 5293934f1615cca0a3516fdb504c4178 282 SUPERFAMILY SSF63817 71 79 1.24E-45 T 29-03-2018 IPR023365 Sortase domain CSW12_RS14905 5293934f1615cca0a3516fdb504c4178 282 SUPERFAMILY SSF63817 108 240 1.24E-45 T 29-03-2018 IPR023365 Sortase domain CSW12_RS14905 5293934f1615cca0a3516fdb504c4178 282 TIGRFAM TIGR01076 sortase_fam: sortase 112 244 1.1E-50 T 29-03-2018 IPR005754 Sortase family CSW12_RS14905 5293934f1615cca0a3516fdb504c4178 282 Gene3D G3DSA:2.40.260.10 46 255 2.7E-55 T 29-03-2018 IPR023365 Sortase domain CSW12_RS14905 5293934f1615cca0a3516fdb504c4178 282 Pfam PF04203 Sortase family 114 238 2.2E-24 T 29-03-2018 IPR005754 Sortase family CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 Gene3D G3DSA:1.10.10.60 40 121 3.4E-11 T 29-03-2018 CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 Gene3D G3DSA:1.10.10.60 2 39 9.8E-17 T 29-03-2018 CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.5E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 SUPERFAMILY SSF46689 5 69 1.08E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS26950 c51cbf82188958ecee043a287540a0fa 289 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 2.9E-18 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS10695 7ad03fcf0087af4770d445af33b1ca59 345 Gene3D G3DSA:3.40.710.10 5 341 1.1E-59 T 29-03-2018 CSW12_RS10695 7ad03fcf0087af4770d445af33b1ca59 345 Pfam PF00144 Beta-lactamase 8 327 5.9E-40 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS10695 7ad03fcf0087af4770d445af33b1ca59 345 SUPERFAMILY SSF56601 7 326 1.86E-61 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 Pfam PF13353 4Fe-4S single cluster domain 21 106 8.0E-7 T 29-03-2018 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 20 31 - T 29-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 337 3.1E-120 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 Pfam PF04055 Radical SAM superfamily 19 180 2.7E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 189 316 9.5E-39 T 29-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 Gene3D G3DSA:3.20.20.70 1 337 7.6E-88 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 5 337 40.93 T 29-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 SMART SM00729 14 222 2.7E-15 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS23315 1ea15a47bae2280508c03c6e13504769 337 SUPERFAMILY SSF102114 7 305 1.27E-83 T 29-03-2018 CSW12_RS25390 94fb936386bc19b8427a03896f91b6ea 294 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25390 94fb936386bc19b8427a03896f91b6ea 294 SMART SM00382 27 206 3.3E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25390 94fb936386bc19b8427a03896f91b6ea 294 SUPERFAMILY SSF52540 3 224 2.96E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25390 94fb936386bc19b8427a03896f91b6ea 294 Gene3D G3DSA:3.40.50.300 1 277 7.3E-59 T 29-03-2018 CSW12_RS25390 94fb936386bc19b8427a03896f91b6ea 294 Pfam PF00005 ABC transporter 19 157 2.4E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25390 94fb936386bc19b8427a03896f91b6ea 294 Pfam PF13732 Domain of unknown function (DUF4162) 211 291 1.6E-10 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 Pfam PF08274 PhnA Zinc-Ribbon 3 31 3.0E-17 T 29-03-2018 IPR013987 PhnA protein, N-terminal CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 Gene3D G3DSA:2.30.30.40 45 112 6.4E-37 T 29-03-2018 CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 Pfam PF03831 PhnA domain 46 113 6.5E-34 T 29-03-2018 IPR013988 PhnA protein, C-terminal CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 Gene3D G3DSA:2.20.25.10 2 40 7.1E-17 T 29-03-2018 CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 SUPERFAMILY SSF82057 41 113 6.87E-29 T 29-03-2018 CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 SUPERFAMILY SSF57783 3 37 6.29E-15 T 29-03-2018 CSW12_RS24520 19ab15fd924e433e927f9d7e5fcf8f7a 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 113 1.9E-51 T 29-03-2018 IPR004624 PhnA protein CSW12_RS12820 7cc8a213655bfec9f7d51af1f0fc7a49 347 SUPERFAMILY SSF53822 34 347 2.03E-80 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS12820 7cc8a213655bfec9f7d51af1f0fc7a49 347 Pfam PF13407 Periplasmic binding protein domain 36 294 6.2E-55 T 29-03-2018 IPR025997 Periplasmic binding protein CSW12_RS12820 7cc8a213655bfec9f7d51af1f0fc7a49 347 Gene3D G3DSA:3.40.50.2300 144 347 1.8E-24 T 29-03-2018 CSW12_RS12820 7cc8a213655bfec9f7d51af1f0fc7a49 347 Gene3D G3DSA:3.40.50.2300 14 143 1.5E-14 T 29-03-2018 CSW12_RS03440 1a32b69b5ab41451edc7ff96b038431f 395 Gene3D G3DSA:1.20.91.10 244 329 1.7E-18 T 29-03-2018 CSW12_RS03440 1a32b69b5ab41451edc7ff96b038431f 395 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 32 299 9.6E-78 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CSW12_RS03440 1a32b69b5ab41451edc7ff96b038431f 395 Pfam PF00999 Sodium/hydrogen exchanger family 28 390 1.6E-78 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CSW12_RS22860 c59d4a14a29656684721d1c17645638a 143 Gene3D G3DSA:3.10.180.10 1 143 2.6E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS22860 c59d4a14a29656684721d1c17645638a 143 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 136 2.3E-7 T 29-03-2018 IPR028973 PhnB-like CSW12_RS22860 c59d4a14a29656684721d1c17645638a 143 SUPERFAMILY SSF54593 2 137 6.22E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 SUPERFAMILY SSF56399 167 371 1.41E-50 T 29-03-2018 CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 SUPERFAMILY SSF56399 7 166 9.71E-23 T 29-03-2018 CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 Gene3D G3DSA:3.90.176.10 168 372 8.2E-47 T 29-03-2018 CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 Gene3D G3DSA:3.90.176.10 4 167 1.4E-13 T 29-03-2018 CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 155 171 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 11 29 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 281 299 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 109 127 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 40 61 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 181 204 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 PRINTS PR01390 Clostridial binary toxin A signature 325 344 2.1E-35 T 29-03-2018 IPR016013 Binary exotoxin A, clostridial type CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 Pfam PF03496 ADP-ribosyltransferase exoenzyme 179 371 4.0E-54 T 29-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 CSW12_RS30280 0bbba166eb71590534870f79438964d4 373 Pfam PF03496 ADP-ribosyltransferase exoenzyme 19 166 2.2E-10 T 29-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 CSW12_RS30365 836007140b31d37f754ffca48c135d77 93 Gene3D G3DSA:2.10.260.10 1 48 1.8E-16 T 29-03-2018 CSW12_RS30365 836007140b31d37f754ffca48c135d77 93 SUPERFAMILY SSF89447 1 50 1.96E-14 T 29-03-2018 CSW12_RS30365 836007140b31d37f754ffca48c135d77 93 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 51 1.4E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS30365 836007140b31d37f754ffca48c135d77 93 SMART SM00966 8 51 1.2E-6 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS30365 836007140b31d37f754ffca48c135d77 93 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 48 2.7E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS23660 a82ec09555d34209bb5c84ab4577253d 178 Pfam PF11667 Putative zincin peptidase 58 163 1.1E-21 T 29-03-2018 IPR021683 Putative zincin peptidase CSW12_RS28445 b145713cb545fc29d34693d9d0b59a4a 283 SUPERFAMILY SSF103481 36 138 2.09E-7 T 29-03-2018 CSW12_RS28445 b145713cb545fc29d34693d9d0b59a4a 283 SUPERFAMILY SSF103481 187 278 2.62E-6 T 29-03-2018 CSW12_RS28445 b145713cb545fc29d34693d9d0b59a4a 283 Pfam PF06800 Sugar transport protein 4 280 1.2E-99 T 29-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 17 373 50.293 T 29-03-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 SUPERFAMILY SSF88697 9 156 5.47E-46 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 Gene3D G3DSA:3.40.50.620 168 369 2.4E-91 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 SUPERFAMILY SSF52374 159 370 3.44E-88 T 29-03-2018 CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 Pfam PF01747 ATP-sulfurylase 159 369 2.7E-95 T 29-03-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 Pfam PF14306 PUA-like domain 21 149 3.7E-47 T 29-03-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 Gene3D G3DSA:3.10.400.10 3 167 1.4E-56 T 29-03-2018 CSW12_RS06690 8b0e28420f30ef7cd333c5870905e23b 378 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 12 369 6.0E-134 T 29-03-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 SUPERFAMILY SSF53335 55 246 4.32E-20 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 Pfam PF01479 S4 domain 6 49 1.6E-6 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 SMART SM00363 6 71 4.2E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 PIRSF PIRSF005578 1 269 2.8E-104 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 Pfam PF01728 FtsJ-like methyltransferase 62 244 2.5E-18 T 29-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 SUPERFAMILY SSF55174 5 71 1.22E-12 T 29-03-2018 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 5.5E-94 T 29-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 Gene3D G3DSA:3.10.290.10 2 64 1.2E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS20465 356c323c96fea18743143adbbc71d42f 279 Gene3D G3DSA:3.40.50.150 65 279 1.6E-59 T 29-03-2018 CSW12_RS19610 1fdb34c31febf9f2b9cf7f2f73eea817 186 Gene3D G3DSA:3.40.50.850 1 164 3.4E-27 T 29-03-2018 CSW12_RS19610 1fdb34c31febf9f2b9cf7f2f73eea817 186 SUPERFAMILY SSF52499 2 175 1.27E-32 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS19610 1fdb34c31febf9f2b9cf7f2f73eea817 186 Pfam PF00857 Isochorismatase family 4 140 1.9E-22 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 358 1.0E-28 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:3.30.1360.120 4 130 1.1E-33 T 29-03-2018 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 SUPERFAMILY SSF101790 275 364 3.92E-27 T 29-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:3.30.1360.120 131 237 2.3E-32 T 29-03-2018 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 3 364 48.658 T 29-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 PIRSF PIRSF006487 1 366 3.9E-109 T 29-03-2018 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 SUPERFAMILY SSF103025 4 283 1.57E-101 T 29-03-2018 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:4.10.1250.10 238 280 7.8E-15 T 29-03-2018 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Gene3D G3DSA:2.40.30.110 283 366 6.4E-28 T 29-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 364 8.7E-146 T 29-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CSW12_RS20735 399a30e8c7fabf25eb039f893dcba44f 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 260 7.0E-98 T 29-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CSW12_RS03535 618d5c9d38653e0a7c7dd69daeb5fc11 183 Pfam PF07366 SnoaL-like polyketide cyclase 63 177 6.5E-33 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CSW12_RS03535 618d5c9d38653e0a7c7dd69daeb5fc11 183 SUPERFAMILY SSF54427 60 180 7.53E-31 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS03535 618d5c9d38653e0a7c7dd69daeb5fc11 183 Gene3D G3DSA:3.10.450.50 25 183 2.8E-24 T 29-03-2018 CSW12_RS24270 fa56795626562546af0fe6ad863cbe33 139 Gene3D G3DSA:3.30.310.100 3 119 4.4E-42 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CSW12_RS24270 fa56795626562546af0fe6ad863cbe33 139 SUPERFAMILY SSF160755 4 135 1.57E-37 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CSW12_RS24270 fa56795626562546af0fe6ad863cbe33 139 Pfam PF08868 YugN-like family 5 134 7.4E-54 T 29-03-2018 IPR014967 Uncharacterised protein family, YugN-like CSW12_RS30585 f9c74d021c6674342b20a0e017c07887 73 Gene3D G3DSA:1.10.10.60 6 73 4.4E-13 T 29-03-2018 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 SUPERFAMILY SSF51306 25 172 8.22E-49 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 ProSitePatterns PS00760 Signal peptidases I lysine active site. 77 89 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 166 1.2E-50 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 ProSitePatterns PS00761 Signal peptidases I signature 3. 130 143 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 Gene3D G3DSA:2.10.109.10 20 173 1.0E-44 T 29-03-2018 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 Pfam PF00717 Peptidase S24-like 30 99 9.9E-20 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 125 144 1.6E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 1.6E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12335 11d20d6cefad169622bb0405cb718026 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 75 87 1.6E-17 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 Gene3D G3DSA:3.10.580.10 195 344 3.6E-30 T 29-03-2018 CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 Gene3D G3DSA:3.30.465.10 345 431 3.1E-18 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 Pfam PF01595 Domain of unknown function DUF21 8 201 3.2E-48 T 29-03-2018 IPR002550 Domain of unknown function DUF21 CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 Pfam PF03471 Transporter associated domain 355 429 5.3E-14 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 SUPERFAMILY SSF56176 351 429 2.51E-14 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 SMART SM01091 354 431 1.2E-18 T 29-03-2018 IPR005170 Transporter-associated domain CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 Pfam PF00571 CBS domain 284 338 3.3E-4 T 29-03-2018 IPR000644 CBS domain CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 Pfam PF00571 CBS domain 222 271 1.2E-7 T 29-03-2018 IPR000644 CBS domain CSW12_RS16535 bdcb8f6d4916affb723e5c1deab920dc 451 SUPERFAMILY SSF54631 204 341 5.94E-33 T 29-03-2018 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 SUPERFAMILY SSF161070 5 443 4.71E-132 T 29-03-2018 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 2.3E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 2.3E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 2.3E-12 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 Pfam PF00209 Sodium:neurotransmitter symporter family 136 441 3.5E-30 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS16965 f7ef334dea85797181814059e57524e7 446 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 3.9E-25 T 29-03-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 Gene3D G3DSA:1.10.520.20 3 106 2.9E-26 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 74 85 2.7E-28 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 151 169 2.7E-28 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 136 151 2.7E-28 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 85 99 2.7E-28 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 PRINTS PR00125 ATP synthase delta subunit signature 6 25 2.7E-28 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 2.8E-52 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 21.658 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 SUPERFAMILY SSF47928 3 105 1.15E-27 T 29-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 29-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26320 72a52279f24ffd1d302ac09dff7a5914 180 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 4.1E-53 T 29-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS00160 6cdd3f09bc63fe1170491f67d3858d75 284 Gene3D G3DSA:3.40.190.10 30 125 9.7E-21 T 29-03-2018 CSW12_RS00160 6cdd3f09bc63fe1170491f67d3858d75 284 Gene3D G3DSA:3.40.190.10 126 272 1.9E-44 T 29-03-2018 CSW12_RS00160 6cdd3f09bc63fe1170491f67d3858d75 284 Pfam PF03180 NLPA lipoprotein 35 270 6.1E-84 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS00160 6cdd3f09bc63fe1170491f67d3858d75 284 PIRSF PIRSF002854 1 274 6.8E-105 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS00160 6cdd3f09bc63fe1170491f67d3858d75 284 SUPERFAMILY SSF53850 35 273 2.77E-82 T 29-03-2018 CSW12_RS29605 0677b718e4096da0fe535442c3f1d67e 355 Pfam PF04235 Protein of unknown function (DUF418) 193 350 1.0E-25 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CSW12_RS29075 0677b718e4096da0fe535442c3f1d67e 355 Pfam PF04235 Protein of unknown function (DUF418) 193 350 1.0E-25 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 PIRSF PIRSF002181 1 143 2.5E-49 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 4.4E-64 T 29-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 27.838 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 SUPERFAMILY SSF52161 5 143 2.22E-59 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 Pfam PF00572 Ribosomal protein L13 15 139 5.7E-56 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 Gene3D G3DSA:3.90.1180.10 1 145 9.7E-60 T 29-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28150 56b311e7d4b788e32c0dff650207b207 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 29-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 Gene3D G3DSA:2.60.40.10 580 690 5.3E-19 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 SMART SM00495 697 743 3.7E-4 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 Gene3D G3DSA:2.10.10.20 700 744 1.7E-10 T 29-03-2018 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 SMART SM00060 606 679 1.1E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 Pfam PF13402 Peptidase M60, enhancin and enhancin-like 165 425 1.4E-55 T 29-03-2018 IPR031161 Peptidase family M60 domain CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 SUPERFAMILY SSF51055 699 741 1.7E-5 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 SUPERFAMILY SSF49265 600 691 2.92E-14 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 SMART SM01276 82 375 7.8E-105 T 29-03-2018 IPR031161 Peptidase family M60 domain CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 Pfam PF03272 Putative mucin or carbohydrate-binding module 477 590 7.5E-28 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS10200 077e09ec5e8cf4d64642a2e61966cf1f 746 Pfam PF17291 N-terminal domain of M60-like peptidases 82 153 2.9E-15 T 29-03-2018 IPR035423 M60-like domain, N-terminal CSW12_RS10970 09502191620909bda4039743be710756 113 Pfam PF08274 PhnA Zinc-Ribbon 4 32 4.2E-17 T 29-03-2018 IPR013987 PhnA protein, N-terminal CSW12_RS10970 09502191620909bda4039743be710756 113 Gene3D G3DSA:2.20.25.10 2 40 2.3E-17 T 29-03-2018 CSW12_RS10970 09502191620909bda4039743be710756 113 SUPERFAMILY SSF57783 3 36 1.05E-14 T 29-03-2018 CSW12_RS10970 09502191620909bda4039743be710756 113 SUPERFAMILY SSF82057 41 113 2.11E-29 T 29-03-2018 CSW12_RS10970 09502191620909bda4039743be710756 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 112 1.8E-50 T 29-03-2018 IPR004624 PhnA protein CSW12_RS10970 09502191620909bda4039743be710756 113 Gene3D G3DSA:2.30.30.40 45 112 2.6E-37 T 29-03-2018 CSW12_RS10970 09502191620909bda4039743be710756 113 Pfam PF03831 PhnA domain 46 113 9.0E-34 T 29-03-2018 IPR013988 PhnA protein, C-terminal CSW12_RS07280 ac4e63ef5379de556e05ac9b0af7e5c5 293 SUPERFAMILY SSF52540 2 219 1.92E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07280 ac4e63ef5379de556e05ac9b0af7e5c5 293 Gene3D G3DSA:3.40.50.300 1 246 9.2E-54 T 29-03-2018 CSW12_RS07280 ac4e63ef5379de556e05ac9b0af7e5c5 293 Pfam PF00005 ABC transporter 17 154 2.4E-28 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS07280 ac4e63ef5379de556e05ac9b0af7e5c5 293 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS07280 ac4e63ef5379de556e05ac9b0af7e5c5 293 SMART SM00382 26 202 5.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 Gene3D G3DSA:3.40.50.300 645 791 1.2E-13 T 29-03-2018 CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 SMART SM00487 438 629 8.6E-21 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 SUPERFAMILY SSF52540 355 614 4.71E-33 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 Gene3D G3DSA:3.40.50.300 430 622 8.7E-28 T 29-03-2018 CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 Pfam PF00271 Helicase conserved C-terminal domain 666 774 1.7E-6 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 SUPERFAMILY SSF52540 559 595 6.18E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 SUPERFAMILY SSF52540 653 803 6.18E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30260 84c3690ada3ef40c4b6f03575ef053d2 951 Pfam PF04851 Type III restriction enzyme, res subunit 442 599 4.4E-19 T 29-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CSW12_RS03460 07fcf45b6c3fff3f40ac70f338e2f0a5 454 SUPERFAMILY SSF55604 7 82 1.44E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS03460 07fcf45b6c3fff3f40ac70f338e2f0a5 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS03460 07fcf45b6c3fff3f40ac70f338e2f0a5 454 Pfam PF00367 phosphotransferase system, EIIB 9 42 2.9E-15 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS03460 07fcf45b6c3fff3f40ac70f338e2f0a5 454 Pfam PF02378 Phosphotransferase system, EIIC 121 389 1.2E-33 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS03460 07fcf45b6c3fff3f40ac70f338e2f0a5 454 Gene3D G3DSA:3.30.1360.60 5 81 1.6E-25 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS06995 04b4f86d419b3a57ffea99caf65d9d86 192 Pfam PF12822 ECF transporter, substrate-specific component 9 177 1.6E-22 T 29-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CSW12_RS06995 04b4f86d419b3a57ffea99caf65d9d86 192 PIRSF PIRSF037778 3 190 1.5E-41 T 29-03-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 Gene3D G3DSA:1.10.287.950 330 580 1.5E-49 T 29-03-2018 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 Gene3D G3DSA:1.10.287.950 74 329 1.5E-9 T 29-03-2018 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 356 531 8.0E-43 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 SUPERFAMILY SSF58104 309 578 2.62E-66 T 29-03-2018 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 SUPERFAMILY SSF58104 250 276 2.62E-66 T 29-03-2018 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 13 38 9.6E-20 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 430 459 9.6E-20 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 428 9.6E-20 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 SMART SM00283 303 578 2.0E-67 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 SMART SM00304 519 575 28.0 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS00785 1d29aa1b96624e3acb23ac7ec3b37b40 580 SMART SM00304 223 274 3.1E-4 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS05090 f1edb208abe1bee98a0286b07f88b95d 309 Gene3D G3DSA:3.40.50.300 11 297 1.2E-5 T 29-03-2018 CSW12_RS05090 f1edb208abe1bee98a0286b07f88b95d 309 Pfam PF13479 AAA domain 13 214 2.1E-12 T 29-03-2018 CSW12_RS05090 f1edb208abe1bee98a0286b07f88b95d 309 SUPERFAMILY SSF52540 15 165 3.28E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09820 76ce37b9ace022085a1ede8d56f25c5b 568 Gene3D G3DSA:3.90.76.10 64 224 2.9E-44 T 29-03-2018 CSW12_RS09820 76ce37b9ace022085a1ede8d56f25c5b 568 Gene3D G3DSA:3.10.105.10 320 536 2.7E-47 T 29-03-2018 CSW12_RS09820 76ce37b9ace022085a1ede8d56f25c5b 568 PIRSF PIRSF002741 2 568 5.3E-108 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS09820 76ce37b9ace022085a1ede8d56f25c5b 568 SUPERFAMILY SSF53850 52 561 4.34E-124 T 29-03-2018 CSW12_RS09820 76ce37b9ace022085a1ede8d56f25c5b 568 Gene3D G3DSA:3.40.190.10 225 319 1.6E-17 T 29-03-2018 CSW12_RS09820 76ce37b9ace022085a1ede8d56f25c5b 568 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 97 484 1.6E-78 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 SMART SM00857 2 141 1.0E-52 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 Gene3D G3DSA:1.20.5.40 107 122 1.9E-17 T 29-03-2018 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 SUPERFAMILY SSF46689 139 178 2.87E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 SUPERFAMILY SSF53041 1 132 3.53E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 ProSitePatterns PS00397 Site-specific recombinases active site. 5 13 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 Gene3D G3DSA:1.10.10.60 123 183 8.3E-7 T 29-03-2018 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 Pfam PF00239 Resolvase, N terminal domain 3 132 2.9E-40 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30575 99802c80670dd0fcd221fedfbe32f397 194 Gene3D G3DSA:3.40.50.1390 2 106 8.9E-33 T 29-03-2018 CSW12_RS18120 dd198d632491e97a32e05fc4b8b15c21 188 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS18120 dd198d632491e97a32e05fc4b8b15c21 188 Gene3D G3DSA:2.160.10.10 1 171 1.2E-32 T 29-03-2018 CSW12_RS18120 dd198d632491e97a32e05fc4b8b15c21 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 37 66 2.6E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS18120 dd198d632491e97a32e05fc4b8b15c21 188 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 150 6.9E-4 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS18120 dd198d632491e97a32e05fc4b8b15c21 188 SUPERFAMILY SSF51161 18 178 4.71E-30 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 Pfam PF01479 S4 domain 2 48 3.1E-17 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 SUPERFAMILY SSF55174 2 67 2.35E-17 T 29-03-2018 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 1.5E-50 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 Pfam PF00849 RNA pseudouridylate synthase 62 196 6.0E-24 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 SUPERFAMILY SSF55120 61 230 1.15E-44 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 SMART SM00363 2 59 1.5E-16 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 Gene3D G3DSA:3.30.2350.10 71 242 1.2E-41 T 29-03-2018 CSW12_RS06950 c0f9e4d5628186bcf41217cb10f65a94 242 Gene3D G3DSA:3.10.290.10 1 70 6.8E-21 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS17100 1e1a4f1e2198379d5aa4a1e53a924f10 127 Pfam PF04134 Protein of unknown function, DUF393 3 109 4.4E-15 T 29-03-2018 IPR007263 Protein of unknown function DUF393 CSW12_RS17100 1e1a4f1e2198379d5aa4a1e53a924f10 127 Gene3D G3DSA:3.40.30.10 1 82 1.3E-8 T 29-03-2018 CSW12_RS17100 1e1a4f1e2198379d5aa4a1e53a924f10 127 SUPERFAMILY SSF52833 2 78 5.56E-8 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS01140 cb15fe596b22ab5b39172736c27dc3ed 518 SUPERFAMILY SSF53448 276 434 1.81E-21 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01140 cb15fe596b22ab5b39172736c27dc3ed 518 SUPERFAMILY SSF53448 5 167 8.59E-23 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01140 cb15fe596b22ab5b39172736c27dc3ed 518 Gene3D G3DSA:3.90.550.10 4 226 1.5E-18 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01140 cb15fe596b22ab5b39172736c27dc3ed 518 Gene3D G3DSA:3.90.550.10 272 474 7.9E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS01140 cb15fe596b22ab5b39172736c27dc3ed 518 Pfam PF00535 Glycosyl transferase family 2 278 390 1.3E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS01140 cb15fe596b22ab5b39172736c27dc3ed 518 Pfam PF00535 Glycosyl transferase family 2 10 124 6.3E-16 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 Pfam PF00717 Peptidase S24-like 35 102 1.2E-20 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 2.1E-57 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 SUPERFAMILY SSF51306 26 181 3.92E-52 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 Gene3D G3DSA:2.10.109.10 24 182 1.3E-47 T 29-03-2018 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 8.2E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 8.2E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 8.2E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS08580 a5ae6b0a0c3846fb1932d80b8d52c273 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CSW12_RS26425 53f437942e8576e2b69d91092ad39890 290 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 40 165 2.9E-47 T 29-03-2018 IPR014202 Sporulation stage II, protein R CSW12_RS26425 53f437942e8576e2b69d91092ad39890 290 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 6 171 2.9E-60 T 29-03-2018 IPR014202 Sporulation stage II, protein R CSW12_RS10495 e5b3c2c2f47d72f86e6c55213c1355ee 223 Gene3D G3DSA:2.60.120.40 98 218 1.8E-7 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS10495 e5b3c2c2f47d72f86e6c55213c1355ee 223 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 13 31 6.2E-7 T 29-03-2018 IPR021201 Leader peptide, exosporium CSW12_RS10495 e5b3c2c2f47d72f86e6c55213c1355ee 223 SUPERFAMILY SSF49842 105 208 7.67E-5 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS10495 e5b3c2c2f47d72f86e6c55213c1355ee 223 Gene3D G3DSA:2.160.20.50 19 89 9.2E-10 T 29-03-2018 CSW12_RS23975 c22abd4f2d96c30ff7624d0403e32faf 286 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 98 213 4.9E-29 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CSW12_RS23975 c22abd4f2d96c30ff7624d0403e32faf 286 Gene3D G3DSA:3.30.1380.10 79 211 6.7E-27 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS23975 c22abd4f2d96c30ff7624d0403e32faf 286 SUPERFAMILY SSF55166 92 222 1.39E-28 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS09625 80f256308d8b937abba73cee9c192e32 193 Gene3D G3DSA:1.10.720.30 18 69 2.1E-8 T 29-03-2018 IPR003034 SAP domain CSW12_RS25835 f8b4ab38832ecb062971c5ff799e423a 364 Gene3D G3DSA:1.50.10.10 28 361 9.9E-50 T 29-03-2018 CSW12_RS25835 f8b4ab38832ecb062971c5ff799e423a 364 SUPERFAMILY SSF48208 11 351 1.19E-45 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CSW12_RS13790 df4078b30d2f37b142f185a4f2f5e8b1 159 Gene3D G3DSA:1.20.120.450 5 154 6.4E-20 T 29-03-2018 CSW12_RS13790 df4078b30d2f37b142f185a4f2f5e8b1 159 SUPERFAMILY SSF109854 27 152 2.01E-22 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS13790 df4078b30d2f37b142f185a4f2f5e8b1 159 Pfam PF12867 DinB superfamily 26 146 2.8E-10 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 547 2.1E-41 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 29-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 SUPERFAMILY SSF81665 87 139 4.58E-17 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 SUPERFAMILY SSF81665 236 330 4.58E-17 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 SUPERFAMILY SSF81665 583 617 4.58E-17 T 29-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00941 Cadmium-transporting ATPase signature 65 77 5.8E-13 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00941 Cadmium-transporting ATPase signature 140 156 5.8E-13 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00941 Cadmium-transporting ATPase signature 220 234 5.8E-13 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00941 Cadmium-transporting ATPase signature 201 217 5.8E-13 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00941 Cadmium-transporting ATPase signature 120 140 5.8E-13 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 Gene3D G3DSA:1.20.1110.10 85 357 7.5E-34 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 85 636 2.7E-187 T 29-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 97 636 2.6E-121 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 SUPERFAMILY SSF56784 409 633 9.16E-58 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 SUPERFAMILY SSF56784 335 354 9.16E-58 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 ProSitePatterns PS01229 Hypothetical cof family signature 2. 534 556 - T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 Pfam PF00122 E1-E2 ATPase 136 316 1.0E-50 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 108 610 6.9E-85 T 29-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 Gene3D G3DSA:3.40.1110.10 358 461 3.4E-27 T 29-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 85 388 2.5E-96 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 SUPERFAMILY SSF81653 138 235 1.96E-24 T 29-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 Gene3D G3DSA:3.40.50.1000 462 600 1.3E-41 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 4.4E-29 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 459 470 4.4E-29 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 557 569 4.4E-29 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 4.4E-29 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 491 4.4E-29 T 29-03-2018 CSW12_RS00955 31520ce845dc6cdeae073bfeac63a58e 641 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 553 4.4E-29 T 29-03-2018 CSW12_RS03970 08c5d6faca00f3e213f72e108780975a 261 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 76 2.2E-23 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CSW12_RS03970 08c5d6faca00f3e213f72e108780975a 261 Gene3D G3DSA:1.10.10.10 2 157 4.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03970 08c5d6faca00f3e213f72e108780975a 261 Pfam PF11495 Archaeal transcriptional regulator TrmB 111 228 1.2E-5 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal CSW12_RS03970 08c5d6faca00f3e213f72e108780975a 261 SUPERFAMILY SSF46785 2 97 3.31E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 2.2E-65 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 SUPERFAMILY SSF51735 1 335 3.25E-99 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 4.0E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 4.0E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 4.0E-5 T 29-03-2018 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-70370 CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 Gene3D G3DSA:3.90.25.10 207 250 1.8E-10 T 29-03-2018 CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 Gene3D G3DSA:3.90.25.10 251 336 1.6E-26 T 29-03-2018 CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 2.2E-149 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CSW12_RS27030 1d47bc8621c388c36f8d6eee459a2159 338 Gene3D G3DSA:3.40.50.720 1 206 1.3E-39 T 29-03-2018 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 SUPERFAMILY SSF53681 116 225 1.83E-32 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 190 200 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 Gene3D G3DSA:3.40.50.1860 1 121 2.2E-25 T 29-03-2018 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 221 1.5E-49 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 225 9.3E-64 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 SUPERFAMILY SSF53681 1 112 1.7E-27 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS14540 4ffecfb090aea40d7bb183fda899d944 226 Gene3D G3DSA:3.40.50.1860 122 226 2.3E-23 T 29-03-2018 CSW12_RS29780 bfdbbec04d318b21127abbeffc99c0b0 398 Gene3D G3DSA:3.40.50.300 249 328 0.022 T 29-03-2018 CSW12_RS29780 bfdbbec04d318b21127abbeffc99c0b0 398 Gene3D G3DSA:3.40.50.300 76 173 0.23 T 29-03-2018 CSW12_RS18410 5d62b1b07ed60cc35e92874a954ffdc2 456 Gene3D G3DSA:3.40.50.1820 115 453 1.5E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS18410 5d62b1b07ed60cc35e92874a954ffdc2 456 SUPERFAMILY SSF53474 203 436 7.58E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS18410 5d62b1b07ed60cc35e92874a954ffdc2 456 SUPERFAMILY SSF53474 104 153 7.58E-29 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS18410 5d62b1b07ed60cc35e92874a954ffdc2 456 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 295 434 1.3E-8 T 29-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 CSW12_RS18410 5d62b1b07ed60cc35e92874a954ffdc2 456 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 112 251 2.4E-11 T 29-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 SUPERFAMILY SSF88946 24 130 4.97E-35 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 PIRSF PIRSF000770 2 239 3.9E-79 T 29-03-2018 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 Pfam PF04545 Sigma-70, region 4 180 233 1.8E-17 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 7.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 7.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 7.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 7.1E-12 T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 3.9E-35 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 7 239 6.5E-138 T 29-03-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 Pfam PF04542 Sigma-70 region 2 62 131 2.1E-18 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 29-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 Gene3D G3DSA:1.10.601.10 32 130 7.0E-32 T 29-03-2018 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 SUPERFAMILY SSF88659 143 237 3.36E-22 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08235 09cdbafcc4851eefd0e17c8916c77fc5 239 Gene3D G3DSA:1.10.1270.10 154 239 1.9E-20 T 29-03-2018 CSW12_RS26545 3dd26ae784f6741cfd881ffe5fb7ec05 285 Gene3D G3DSA:1.25.40.10 147 279 1.0E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS26545 3dd26ae784f6741cfd881ffe5fb7ec05 285 Gene3D G3DSA:1.10.3100.10 1 146 1.6E-15 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS26545 3dd26ae784f6741cfd881ffe5fb7ec05 285 SMART SM00530 9 63 4.5E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS26545 3dd26ae784f6741cfd881ffe5fb7ec05 285 SUPERFAMILY SSF48452 154 252 1.33E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS26545 3dd26ae784f6741cfd881ffe5fb7ec05 285 Pfam PF01381 Helix-turn-helix 10 60 3.5E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS26545 3dd26ae784f6741cfd881ffe5fb7ec05 285 SUPERFAMILY SSF47413 5 64 4.79E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 Gene3D G3DSA:1.25.40.20 121 226 1.3E-27 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 PRINTS PR01415 Ankyrin repeat signature 130 145 3.8E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 PRINTS PR01415 Ankyrin repeat signature 184 198 3.8E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 SUPERFAMILY SSF48403 29 223 8.34E-52 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 Gene3D G3DSA:1.20.120.660 10 86 9.8E-17 T 29-03-2018 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 SMART SM00248 63 92 5.0E-6 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 SMART SM00248 96 125 84.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 SMART SM00248 129 159 100.0 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 SMART SM00248 30 59 7.3 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 SMART SM00248 163 197 0.29 T 29-03-2018 IPR002110 Ankyrin repeat GO:0005515 CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 Gene3D G3DSA:1.25.40.20 87 120 2.0E-13 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 Pfam PF12796 Ankyrin repeats (3 copies) 103 199 3.2E-12 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS23010 db8aad7cf3750e510e9df583d553eccd 226 Pfam PF12796 Ankyrin repeats (3 copies) 15 94 1.0E-12 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS00455 6008170a3095c7a06b4254733f1c6b54 483 Gene3D G3DSA:3.40.309.10 273 465 3.3E-74 T 29-03-2018 CSW12_RS00455 6008170a3095c7a06b4254733f1c6b54 483 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 477 2.3E-203 T 29-03-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CSW12_RS00455 6008170a3095c7a06b4254733f1c6b54 483 Gene3D G3DSA:3.40.605.10 9 272 6.5E-103 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS00455 6008170a3095c7a06b4254733f1c6b54 483 SUPERFAMILY SSF53720 13 482 3.93E-173 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS00455 6008170a3095c7a06b4254733f1c6b54 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS00455 6008170a3095c7a06b4254733f1c6b54 483 Pfam PF00171 Aldehyde dehydrogenase family 25 478 3.4E-173 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS29235 65292d3a1f6ed622273bf45a9720709c 286 Gene3D G3DSA:1.10.10.10 3 98 1.7E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29235 65292d3a1f6ed622273bf45a9720709c 286 Pfam PF13814 Replication-relaxation 17 211 1.1E-14 T 29-03-2018 IPR025855 Plasmid replication-relaxation CSW12_RS29235 65292d3a1f6ed622273bf45a9720709c 286 SUPERFAMILY SSF46785 25 101 3.53E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03660 c60969d740c65320c95251310a59d325 767 SMART SM00387 671 766 1.4E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03660 c60969d740c65320c95251310a59d325 767 Gene3D G3DSA:3.30.565.10 637 767 3.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03660 c60969d740c65320c95251310a59d325 767 Pfam PF07730 Histidine kinase 568 631 1.3E-4 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS03660 c60969d740c65320c95251310a59d325 767 SUPERFAMILY SSF55874 641 762 5.63E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03660 c60969d740c65320c95251310a59d325 767 Gene3D G3DSA:2.30.42.10 27 110 6.6E-5 T 29-03-2018 CSW12_RS03660 c60969d740c65320c95251310a59d325 767 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 673 764 8.3E-8 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS03660 c60969d740c65320c95251310a59d325 767 SUPERFAMILY SSF50156 43 119 2.5E-6 T 29-03-2018 IPR001478 PDZ domain GO:0005515 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 1 518 29.417 T 29-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 SUPERFAMILY SSF48163 323 517 7.98E-18 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 1 514 2.2E-125 T 29-03-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 Gene3D G3DSA:3.40.50.620 1 270 5.9E-54 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 29 38 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 SUPERFAMILY SSF52374 2 314 5.9E-62 T 29-03-2018 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 Gene3D G3DSA:1.10.730.10 271 489 2.1E-9 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS14765 4fad91e46d02b4b7e510949480ccd140 518 Pfam PF01921 tRNA synthetases class I (K) 1 351 7.3E-123 T 29-03-2018 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Pfam PF00175 Oxidoreductase NAD-binding domain 113 202 2.7E-4 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Gene3D G3DSA:2.40.30.10 1 98 2.7E-15 T 29-03-2018 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 257 7.9E-17 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 259 38.4 T 29-03-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 SUPERFAMILY SSF52343 95 258 8.91E-31 T 29-03-2018 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Gene3D G3DSA:2.10.240.10 216 258 3.0E-17 T 29-03-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 PIRSF PIRSF006816 1 259 8.2E-70 T 29-03-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 SUPERFAMILY SSF63380 1 100 6.09E-22 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Gene3D G3DSA:3.40.50.80 102 212 1.9E-10 T 29-03-2018 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 Pfam PF00970 Oxidoreductase FAD-binding domain 8 98 1.5E-4 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 5.3E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 112 131 5.3E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CSW12_RS08330 0a09135143c3d5dd8cc2ff95f77cab70 259 PRINTS PR00409 Phthalate dioxygenase reductase family signature 189 197 5.3E-8 T 29-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CSW12_RS13955 5a65aedcad8544085ef155a7159a56a9 118 Gene3D G3DSA:3.30.1450.10 38 118 2.3E-15 T 29-03-2018 CSW12_RS09880 9e241294bbe4578ca81f6f9fe5067da0 511 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 38 491 3.5E-172 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS09880 9e241294bbe4578ca81f6f9fe5067da0 511 PIRSF PIRSF005690 24 507 2.0E-187 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Pfam PF02743 Cache domain 30 249 8.0E-26 T 29-03-2018 IPR033479 Double Cache domain 1 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 SMART SM00283 368 643 2.5E-82 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Pfam PF00672 HAMP domain 287 335 1.6E-16 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 417 594 3.4E-45 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 SMART SM00319 17 135 6.6E-4 T 29-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Gene3D G3DSA:1.10.287.950 285 383 4.6E-7 T 29-03-2018 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Gene3D G3DSA:1.10.287.950 556 636 2.5E-8 T 29-03-2018 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Gene3D G3DSA:1.10.287.950 384 555 1.3E-47 T 29-03-2018 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 Gene3D G3DSA:3.30.450.20 127 263 5.2E-18 T 29-03-2018 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 SUPERFAMILY SSF103190 79 174 2.47E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 SUPERFAMILY SSF58104 374 643 4.19E-75 T 29-03-2018 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 SUPERFAMILY SSF58104 307 341 4.19E-75 T 29-03-2018 CSW12_RS10240 df27d43e2d5d14e32205eaab89894ae2 644 SMART SM00304 287 339 3.5E-17 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS06025 6d895522851d184761010f054a761891 470 Gene3D G3DSA:1.10.45.10 418 457 2.2E-17 T 29-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CSW12_RS06025 6d895522851d184761010f054a761891 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 456 5.2E-74 T 29-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CSW12_RS06025 6d895522851d184761010f054a761891 470 Gene3D G3DSA:3.30.465.10 94 239 3.3E-44 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS06025 6d895522851d184761010f054a761891 470 SUPERFAMILY SSF56176 5 217 5.14E-76 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS06025 6d895522851d184761010f054a761891 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 7.0E-181 T 29-03-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 CSW12_RS06025 6d895522851d184761010f054a761891 470 SUPERFAMILY SSF55103 220 460 9.97E-71 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CSW12_RS06025 6d895522851d184761010f054a761891 470 Gene3D G3DSA:3.30.43.10 3 93 7.2E-23 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS06025 6d895522851d184761010f054a761891 470 Pfam PF01565 FAD binding domain 41 180 1.0E-42 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS07685 bcc9f392cb6dcc594ea51c15af394d17 387 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CSW12_RS07685 bcc9f392cb6dcc594ea51c15af394d17 387 Gene3D G3DSA:3.40.640.10 43 294 3.4E-63 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS07685 bcc9f392cb6dcc594ea51c15af394d17 387 SUPERFAMILY SSF53383 4 383 1.75E-114 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS07685 bcc9f392cb6dcc594ea51c15af394d17 387 Gene3D G3DSA:3.90.1150.10 295 385 8.4E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS07685 bcc9f392cb6dcc594ea51c15af394d17 387 Pfam PF00155 Aminotransferase class I and II 29 377 2.4E-70 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS00530 71c695c145bf3f8c50e9fed35648ac12 423 Gene3D G3DSA:1.10.10.10 333 418 3.6E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00530 71c695c145bf3f8c50e9fed35648ac12 423 Gene3D G3DSA:3.40.50.2300 1 99 0.002 T 29-03-2018 CSW12_RS07490 173fa85e8b003cbb7a70a42734a79d7b 170 Gene3D G3DSA:2.60.120.10 1 160 2.7E-36 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS07490 173fa85e8b003cbb7a70a42734a79d7b 170 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 170 26.368 T 29-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 CSW12_RS07490 173fa85e8b003cbb7a70a42734a79d7b 170 Pfam PF03079 ARD/ARD' family 3 168 8.0E-44 T 29-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 CSW12_RS07490 173fa85e8b003cbb7a70a42734a79d7b 170 SUPERFAMILY SSF51182 8 170 1.35E-31 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS06740 86c554dc6c9c8e1d2f508c6b58170423 424 SUPERFAMILY SSF51261 250 422 9.94E-44 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS06740 86c554dc6c9c8e1d2f508c6b58170423 424 Gene3D G3DSA:1.20.5.50 158 247 0.09 T 29-03-2018 CSW12_RS06740 86c554dc6c9c8e1d2f508c6b58170423 424 Pfam PF01551 Peptidase family M23 315 412 7.8E-30 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS06740 86c554dc6c9c8e1d2f508c6b58170423 424 Gene3D G3DSA:2.70.70.10 248 423 7.0E-45 T 29-03-2018 CSW12_RS06740 86c554dc6c9c8e1d2f508c6b58170423 424 Gene3D G3DSA:1.20.120.330 24 151 1.4E-8 T 29-03-2018 CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 Pfam PF17384 RimP C-terminal SH3 domain 87 156 1.7E-22 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 Pfam PF02576 RimP N-terminal domain 13 84 6.5E-28 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 Gene3D G3DSA:2.30.30.180 88 154 2.2E-22 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 SUPERFAMILY SSF74942 85 156 9.15E-22 T 29-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 Gene3D G3DSA:3.30.300.70 1 81 1.1E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 24.677 T 29-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CSW12_RS08695 3aa78d13f5b5db907a649f7df0162c01 156 SUPERFAMILY SSF75420 4 84 3.79E-26 T 29-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 252 281 3.0E-5 T 29-03-2018 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 214 243 6.2E-8 T 29-03-2018 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 18 43 1.3E-5 T 29-03-2018 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 100 128 2.9E-5 T 29-03-2018 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 138 167 1.7E-5 T 29-03-2018 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 217 227 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 ProSitePatterns PS00626 Regulator of chromosome condensation (RCC1) signature 2. 18 28 - T 29-03-2018 IPR000408 Regulator of chromosome condensation, RCC1 CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 SUPERFAMILY SSF50985 67 293 2.75E-44 T 29-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 208 246 8.4E-11 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 94 131 2.7E-6 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 9 45 1.7E-5 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 46 93 0.033 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 247 291 3.5E-10 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 171 207 3.1E-5 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS18640 2cd7e9617d8cf87c8227790ede072038 295 Gene3D G3DSA:3.10.100.10 132 170 2.6E-7 T 29-03-2018 IPR016186 C-type lectin-like/link domain CSW12_RS07360 40828cb7d27b44b50bd25cf522613cc8 261 SUPERFAMILY SSF56784 1 252 2.56E-52 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07360 40828cb7d27b44b50bd25cf522613cc8 261 Gene3D G3DSA:3.40.50.1000 1 250 5.8E-27 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07360 40828cb7d27b44b50bd25cf522613cc8 261 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 3.0E-45 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS07360 40828cb7d27b44b50bd25cf522613cc8 261 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 252 4.8E-46 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07360 40828cb7d27b44b50bd25cf522613cc8 261 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 231 6.0E-25 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS24400 1002a61b10f31273d5f2e10a35dc5063 219 SUPERFAMILY SSF50685 126 168 4.53E-7 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS24400 1002a61b10f31273d5f2e10a35dc5063 219 Gene3D G3DSA:2.40.40.10 43 200 8.1E-34 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS24400 1002a61b10f31273d5f2e10a35dc5063 219 Pfam PF06725 3D domain 126 187 6.8E-19 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CSW12_RS26480 9f6738bd0437b4efb931d8d72408dcec 174 Gene3D G3DSA:3.40.50.10490 16 170 5.0E-7 T 29-03-2018 CSW12_RS26480 9f6738bd0437b4efb931d8d72408dcec 174 SUPERFAMILY SSF53697 22 169 2.26E-5 T 29-03-2018 CSW12_RS26480 9f6738bd0437b4efb931d8d72408dcec 174 Pfam PF10740 Domain of unknown function (DUF2529) 1 171 1.3E-66 T 29-03-2018 IPR019676 Domain of unknown function (DUF2529) CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 Gene3D G3DSA:1.10.10.10 4 80 3.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 Pfam PF00155 Aminotransferase class I and II 135 456 1.5E-12 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 SUPERFAMILY SSF53383 74 462 1.3E-73 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 Gene3D G3DSA:3.40.640.10 122 365 4.4E-27 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 SUPERFAMILY SSF46785 9 83 9.98E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 9.6E-13 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 SMART SM00345 20 79 5.4E-10 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 9.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 9.1E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01625 f1a72267c3a79de7e084467e9bc9ae18 466 Gene3D G3DSA:3.90.1150.10 366 465 8.7E-20 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS00120 4165400dca6d714d25683ca18c67e5a9 398 PIRSF PIRSF012509 1 398 1.1E-148 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CSW12_RS00120 4165400dca6d714d25683ca18c67e5a9 398 Gene3D G3DSA:3.10.570.10 36 398 5.0E-121 T 29-03-2018 CSW12_RS00120 4165400dca6d714d25683ca18c67e5a9 398 Pfam PF07537 CamS sex pheromone cAM373 precursor 57 390 1.3E-112 T 29-03-2018 IPR011426 CamS sex pheromone cAM373 CSW12_RS25170 6716a9b4350208c6d1943e6105babf52 134 SMART SM00317 3 120 1.0E-9 T 29-03-2018 IPR001214 SET domain GO:0005515 CSW12_RS25170 6716a9b4350208c6d1943e6105babf52 134 Pfam PF00856 SET domain 19 114 3.9E-15 T 29-03-2018 IPR001214 SET domain GO:0005515 CSW12_RS25170 6716a9b4350208c6d1943e6105babf52 134 SUPERFAMILY SSF82199 5 116 4.84E-23 T 29-03-2018 CSW12_RS25170 6716a9b4350208c6d1943e6105babf52 134 Gene3D G3DSA:2.170.270.10 3 122 1.9E-21 T 29-03-2018 CSW12_RS25170 6716a9b4350208c6d1943e6105babf52 134 PIRSF PIRSF022536 1 134 6.2E-32 T 29-03-2018 IPR009207 Histone methyltransferase, PBCV type putative KEGG: 00310+2.1.1.43 CSW12_RS11705 67402870a24c40333e64ffa763a351c4 596 Pfam PF00326 Prolyl oligopeptidase family 390 595 2.7E-43 T 29-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CSW12_RS11705 67402870a24c40333e64ffa763a351c4 596 Gene3D G3DSA:2.120.10.30 148 305 1.4E-5 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CSW12_RS11705 67402870a24c40333e64ffa763a351c4 596 Gene3D G3DSA:3.40.50.1820 306 596 3.6E-49 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11705 67402870a24c40333e64ffa763a351c4 596 SUPERFAMILY SSF69322 12 308 5.75E-16 T 29-03-2018 CSW12_RS11705 67402870a24c40333e64ffa763a351c4 596 SUPERFAMILY SSF53474 345 595 1.56E-62 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11705 67402870a24c40333e64ffa763a351c4 596 Gene3D G3DSA:2.140.10.30 8 147 1.1E-10 T 29-03-2018 CSW12_RS10845 de9d0cb56d812b5c6f56af0ff07a84d9 156 Gene3D G3DSA:3.40.30.10 28 154 3.6E-4 T 29-03-2018 CSW12_RS21980 d9c6f262b83493c96f53cf07a982e6ca 138 Gene3D G3DSA:2.20.25.10 1 44 2.9E-19 T 29-03-2018 CSW12_RS21980 d9c6f262b83493c96f53cf07a982e6ca 138 Gene3D G3DSA:3.30.300.20 45 138 5.8E-27 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS21980 d9c6f262b83493c96f53cf07a982e6ca 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 3.2E-56 T 29-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CSW12_RS21980 d9c6f262b83493c96f53cf07a982e6ca 138 SUPERFAMILY SSF82784 1 137 1.44E-42 T 29-03-2018 IPR003718 OsmC/Ohr family CSW12_RS21980 d9c6f262b83493c96f53cf07a982e6ca 138 Pfam PF02566 OsmC-like protein 40 135 4.8E-18 T 29-03-2018 IPR003718 OsmC/Ohr family CSW12_RS04240 2a9014e2fac280c825b27eeb42c6cddb 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 32 3.5E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS04240 2a9014e2fac280c825b27eeb42c6cddb 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 34 1.2E-10 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS27455 8e95aa4b73d1a784f4f776083ff607c9 89 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 2.5E-28 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CSW12_RS27455 8e95aa4b73d1a784f4f776083ff607c9 89 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 84 9.3E-21 T 29-03-2018 IPR010001 SigmaK-factor processing regulatory BofA CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 Pfam PF02872 5'-nucleotidase, C-terminal domain 357 508 2.4E-23 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 Gene3D G3DSA:3.60.21.10 28 354 9.2E-69 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 SUPERFAMILY SSF56300 32 343 9.19E-75 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 SUPERFAMILY SSF55816 357 569 5.76E-27 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 Pfam PF00149 Calcineurin-like phosphoesterase 40 258 1.2E-10 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 Gene3D G3DSA:3.90.780.10 355 579 1.8E-31 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 PRINTS PR01607 Apyrase family signature 241 264 3.8E-9 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 PRINTS PR01607 Apyrase family signature 268 288 3.8E-9 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 PRINTS PR01607 Apyrase family signature 214 231 3.8E-9 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS14025 d0afb8285877277ba70304da22ca0619 650 PRINTS PR01607 Apyrase family signature 37 55 3.8E-9 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS16155 1d56e88689d58ed0625e6fddb3cc8949 249 Gene3D G3DSA:3.90.470.20 133 229 7.5E-14 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS16155 1d56e88689d58ed0625e6fddb3cc8949 249 SUPERFAMILY SSF56214 121 235 4.19E-21 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS16155 1d56e88689d58ed0625e6fddb3cc8949 249 Gene3D G3DSA:3.90.470.20 18 132 2.3E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS16155 1d56e88689d58ed0625e6fddb3cc8949 249 SUPERFAMILY SSF56214 18 113 2.79E-16 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS16155 1d56e88689d58ed0625e6fddb3cc8949 249 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 121 207 1.4E-12 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 Gene3D G3DSA:3.90.78.10 222 301 3.8E-26 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 SUPERFAMILY SSF56176 14 193 2.7E-39 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 Gene3D G3DSA:3.30.43.10 11 84 5.1E-22 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 2.3E-28 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 SUPERFAMILY SSF56194 197 300 5.62E-37 T 29-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 Pfam PF01565 FAD binding domain 35 161 1.2E-22 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 Gene3D G3DSA:3.30.465.10 88 221 1.0E-33 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 1.4E-96 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS08210 9287af4dbe1ad98c704dad3f60b77ec3 301 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 301 89.125 T 29-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS22830 295c669840b080dc2887301e49c92805 131 PIRSF PIRSF021377 1 130 7.2E-55 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS22830 295c669840b080dc2887301e49c92805 131 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 2 122 2.2E-50 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS22830 295c669840b080dc2887301e49c92805 131 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 30 113 1.7E-29 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 Pfam PF13247 4Fe-4S dicluster domain 173 270 3.2E-37 T 29-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 Gene3D G3DSA:3.30.70.20 235 366 1.4E-31 T 29-03-2018 CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 Gene3D G3DSA:1.10.3650.10 367 435 1.1E-27 T 29-03-2018 CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 357 436 4.6E-28 T 29-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 486 2.1E-276 T 29-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 Gene3D G3DSA:3.30.70.20 197 234 5.7E-17 T 29-03-2018 CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 SUPERFAMILY SSF54862 2 489 1.47E-164 T 29-03-2018 CSW12_RS17285 ca8bd00d65780a2279c0f16f0b8a87b4 491 Gene3D G3DSA:3.30.70.20 5 196 2.1E-29 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 Gene3D G3DSA:1.20.1250.20 70 283 1.6E-32 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 Pfam PF07690 Major Facilitator Superfamily 103 494 2.6E-53 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 Gene3D G3DSA:1.20.1250.20 344 599 5.0E-26 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 SUPERFAMILY SSF103473 90 278 6.41E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 SUPERFAMILY SSF103473 564 593 6.41E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 SUPERFAMILY SSF103473 333 504 6.41E-68 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 387 411 9.6E-12 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 126 9.6E-12 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 193 213 9.6E-12 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 PRINTS PR01036 Tetracycline resistance protein TetB signature 223 247 9.6E-12 T 29-03-2018 CSW12_RS22455 9eed158de98b831710743a3da9f1e361 599 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 100 587 4.4E-138 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS23165 dc71cbc47f34a9e855a21698ed33c198 103 Gene3D G3DSA:3.10.450.40 30 103 0.0047 T 29-03-2018 CSW12_RS23165 dc71cbc47f34a9e855a21698ed33c198 103 Pfam PF03413 Peptidase propeptide and YPEB domain 30 100 3.5E-9 T 29-03-2018 IPR025711 PepSY domain CSW12_RS17535 bd347db5d25a6fbb01e521192789e0db 142 SUPERFAMILY SSF141322 79 139 1.44E-15 T 29-03-2018 CSW12_RS17535 bd347db5d25a6fbb01e521192789e0db 142 Gene3D G3DSA:2.40.50.140 77 142 2.7E-15 T 29-03-2018 CSW12_RS17535 bd347db5d25a6fbb01e521192789e0db 142 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 140 3.0E-21 T 29-03-2018 IPR002810 NfeD-like, C-terminal domain CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 290 40.47 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 SUPERFAMILY SSF64397 2 241 4.71E-79 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 Gene3D G3DSA:3.55.30.10 2 234 1.6E-75 T 29-03-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 SUPERFAMILY SSF118352 232 289 2.35E-18 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 PIRSF PIRSF005261 1 290 9.0E-76 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 Pfam PF01430 Hsp33 protein 3 279 1.1E-89 T 29-03-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CSW12_RS27690 0da240ea6046813f5dd05eaaaf0dad8d 290 Gene3D G3DSA:3.90.1280.10 235 287 1.8E-22 T 29-03-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CSW12_RS21935 419def4e64f15b266e9e94af93b5b0ce 326 Gene3D G3DSA:3.10.350.10 272 326 4.6E-9 T 29-03-2018 CSW12_RS21935 419def4e64f15b266e9e94af93b5b0ce 326 SMART SM00257 276 319 6.7E-5 T 29-03-2018 IPR018392 LysM domain CSW12_RS21935 419def4e64f15b266e9e94af93b5b0ce 326 Pfam PF01476 LysM domain 277 319 1.1E-6 T 29-03-2018 IPR018392 LysM domain CSW12_RS21935 419def4e64f15b266e9e94af93b5b0ce 326 SUPERFAMILY SSF54106 275 320 3.14E-9 T 29-03-2018 IPR018392 LysM domain CSW12_RS21935 419def4e64f15b266e9e94af93b5b0ce 326 TIGRFAM TIGR02907 spore_VI_D: stage VI sporulation protein D 7 319 3.2E-131 T 29-03-2018 IPR014256 Sporulation stage VI, protein D CSW12_RS03515 4752e3a3ebc212c69b613c513ec5310b 104 SUPERFAMILY SSF103481 4 100 3.53E-14 T 29-03-2018 CSW12_RS03515 4752e3a3ebc212c69b613c513ec5310b 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.4E-23 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 299 19.169 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 216 7.0E-83 T 29-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 1.7E-57 T 29-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 Gene3D G3DSA:3.30.2350.10 1 227 1.4E-83 T 29-03-2018 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 4.9E-10 T 29-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 SUPERFAMILY SSF55120 1 221 1.41E-79 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS08730 a156d2f895afce44e2d404df6287a92d 307 Gene3D G3DSA:2.30.130.10 234 299 5.9E-5 T 29-03-2018 IPR002478 PUA domain GO:0003723 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 SUPERFAMILY SSF50022 423 505 1.83E-24 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 490 502 5.1E-8 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 457 468 5.1E-8 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 PRINTS PR00162 Rieske 2Fe-2S subunit signature 478 490 5.1E-8 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 Pfam PF00355 Rieske [2Fe-2S] domain 423 504 8.2E-14 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 Gene3D G3DSA:2.102.10.10 411 508 5.8E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 Gene3D G3DSA:3.50.50.60 20 410 2.3E-33 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 SUPERFAMILY SSF51905 30 284 1.23E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 SUPERFAMILY SSF51905 329 385 1.23E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00665 41952c7990f8d08e4f345b58277c7509 508 Pfam PF01266 FAD dependent oxidoreductase 33 376 1.6E-42 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS29180 150fad0338f3997e5dbc1c2a388870f3 376 SUPERFAMILY SSF51261 242 374 5.75E-37 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS29180 150fad0338f3997e5dbc1c2a388870f3 376 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 106 182 1.5E-11 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CSW12_RS29180 150fad0338f3997e5dbc1c2a388870f3 376 Gene3D G3DSA:2.70.70.10 247 376 7.9E-33 T 29-03-2018 CSW12_RS29180 150fad0338f3997e5dbc1c2a388870f3 376 Gene3D G3DSA:1.10.530.10 98 246 4.4E-11 T 29-03-2018 CSW12_RS29180 150fad0338f3997e5dbc1c2a388870f3 376 Pfam PF01551 Peptidase family M23 267 361 1.2E-25 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 246 269 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 38 57 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 91 110 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 477 502 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 213 230 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 397 420 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 557 582 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 457 475 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 132 150 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 512 529 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 PRINTS PR01391 Binary toxin B family signature 272 298 2.4E-80 T 29-03-2018 IPR003896 Bacterial exotoxin B GO:0005576|GO:0009405 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Pfam PF17475 Clostridial binary toxin B/anthrax toxin PA domain 2 292 508 1.8E-39 T 29-03-2018 IPR027439 Protective antigen, heptamerisation domain GO:0051260 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Gene3D G3DSA:3.10.20.110 526 629 1.3E-23 T 29-03-2018 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Pfam PF03495 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain 213 288 5.5E-14 T 29-03-2018 IPR035088 Protective antigen, Ca-binding domain CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 SUPERFAMILY SSF56988 45 627 3.53E-137 T 29-03-2018 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Gene3D G3DSA:3.90.182.10 29 289 4.1E-40 T 29-03-2018 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Pfam PF07691 PA14 domain 44 179 1.7E-15 T 29-03-2018 IPR011658 PA14 domain CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Gene3D G3DSA:2.60.120.240 290 522 1.1E-74 T 29-03-2018 IPR027439 Protective antigen, heptamerisation domain GO:0051260 CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 SMART SM00758 43 180 1.2E-14 T 29-03-2018 IPR011658 PA14 domain CSW12_RS30285 18d1015a2a201d012ce23c777b876f38 699 Pfam PF17476 Clostridial binary toxin B/anthrax toxin PA domain 3 518 614 1.1E-5 T 29-03-2018 IPR035331 Clostridial binary toxin B/anthrax toxin PA, domain 3 CSW12_RS23150 e80de77aafbf27fedd356fcfb6d2d555 104 Gene3D G3DSA:3.40.30.10 1 104 4.4E-22 T 29-03-2018 CSW12_RS23150 e80de77aafbf27fedd356fcfb6d2d555 104 SUPERFAMILY SSF52833 4 102 1.37E-26 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS23150 e80de77aafbf27fedd356fcfb6d2d555 104 Pfam PF00085 Thioredoxin 11 101 6.0E-17 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CSW12_RS07375 e10547976b7c2c0613998345767337e1 122 SUPERFAMILY SSF55729 6 97 6.81E-12 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS07375 e10547976b7c2c0613998345767337e1 122 Pfam PF00583 Acetyltransferase (GNAT) family 35 98 4.1E-8 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS07375 e10547976b7c2c0613998345767337e1 122 Gene3D G3DSA:3.40.630.30 4 116 5.3E-9 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 Pfam PF00117 Glutamine amidotransferase class-I 4 186 3.5E-55 T 29-03-2018 IPR017926 Glutamine amidotransferase CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 99 107 8.0E-36 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 119 131 8.0E-36 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 74 85 8.0E-36 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 2 16 8.0E-36 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 47 56 8.0E-36 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00097 Anthranilate synthase component II signature 164 177 8.0E-36 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.2E-88 T 29-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.3E-13 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.2E-7 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.2E-7 T 29-03-2018 CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 Gene3D G3DSA:3.40.50.880 1 190 5.3E-59 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS27705 2b7f59e91df012bd9ee960d7cd3fb331 195 SUPERFAMILY SSF52317 1 187 1.53E-57 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 SMART SM01193 4 134 4.3E-101 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 29-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PIRSF PIRSF001400 1 428 5.4E-198 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 SUPERFAMILY SSF51604 138 428 2.4E-133 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 SMART SM01192 139 428 8.5E-227 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 Hamap MF_00318 Enolase [eno]. 2 414 46.27 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 3.4E-142 T 29-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 366 383 1.5E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 107 123 1.5E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 314 325 1.5E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 337 351 1.5E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 37 51 1.5E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 PRINTS PR00148 Enolase signature 161 174 1.5E-46 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 Gene3D G3DSA:3.30.390.10 3 125 3.5E-56 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 1.4E-218 T 29-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 Gene3D G3DSA:3.20.20.120 128 431 2.6E-108 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 SUPERFAMILY SSF54826 3 138 3.98E-61 T 29-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25340 39ac911f45dcc424720dd7e6f84f9b0d 431 Pfam PF03952 Enolase, N-terminal domain 4 134 2.0E-62 T 29-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Gene3D G3DSA:2.160.10.10 87 239 1.7E-46 T 29-03-2018 CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 46.565 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 SUPERFAMILY SSF51161 88 226 1.26E-51 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 200 3.0E-9 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 119 2.5E-5 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 5.5E-10 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 3.6E-36 T 29-03-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 9.5E-118 T 29-03-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 CSW12_RS07830 b6b0d2cad7c399d6e96c555cd47d4ed1 240 Gene3D G3DSA:3.30.70.250 3 86 2.8E-38 T 29-03-2018 CSW12_RS01155 8638a8f917a94e08cc047c7cb8234559 243 Pfam PF04055 Radical SAM superfamily 23 184 2.4E-30 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS01155 8638a8f917a94e08cc047c7cb8234559 243 Pfam PF13353 4Fe-4S single cluster domain 15 146 7.2E-23 T 29-03-2018 CSW12_RS01155 8638a8f917a94e08cc047c7cb8234559 243 SUPERFAMILY SSF102114 21 221 1.44E-27 T 29-03-2018 CSW12_RS01155 8638a8f917a94e08cc047c7cb8234559 243 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 241 3.3E-103 T 29-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CSW12_RS01155 8638a8f917a94e08cc047c7cb8234559 243 ProSitePatterns PS01087 Radical activating enzymes signature. 17 38 - T 29-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CSW12_RS01155 8638a8f917a94e08cc047c7cb8234559 243 Gene3D G3DSA:3.80.30.10 67 243 4.5E-41 T 29-03-2018 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 Gene3D G3DSA:1.10.10.10 121 215 1.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 5.4E-12 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.1E-5 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 SMART SM00448 2 114 1.9E-16 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 SMART SM00421 150 207 3.0E-10 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 SUPERFAMILY SSF52172 1 129 2.56E-23 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 Gene3D G3DSA:3.40.50.2300 1 120 5.4E-23 T 29-03-2018 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 SUPERFAMILY SSF46894 148 212 1.19E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS03665 6f3a27e6a28d43393f122acac8e5281f 218 Pfam PF00072 Response regulator receiver domain 4 115 9.3E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 8.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 8.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 8.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 SUPERFAMILY SSF46955 8 110 6.96E-25 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 SMART SM00422 7 76 3.1E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 Pfam PF13411 MerR HTH family regulatory protein 8 74 1.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 Pfam PF07739 TipAS antibiotic-recognition domain 155 245 3.3E-8 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CSW12_RS24060 2eacd6b4ba52c9e73be9166316959720 256 Gene3D G3DSA:1.10.1660.10 5 145 3.9E-30 T 29-03-2018 CSW12_RS19315 3f98e436b137a0a275b4483f37cdb2d0 190 Pfam PF03963 Flagellar hook capping protein - N-terminal region 33 99 8.2E-17 T 29-03-2018 IPR005648 Flagellar hook capping protein CSW12_RS11910 68f90164769081f21d0a0772326a39ae 388 Pfam PF00144 Beta-lactamase 63 371 4.5E-65 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS11910 68f90164769081f21d0a0772326a39ae 388 Gene3D G3DSA:3.40.710.10 43 383 4.0E-75 T 29-03-2018 CSW12_RS11910 68f90164769081f21d0a0772326a39ae 388 SUPERFAMILY SSF56601 51 372 1.1E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS24365 f0e0e3bc403eb4f303e6bf704194619d 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 5 120 1.0E-35 T 29-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CSW12_RS24365 f0e0e3bc403eb4f303e6bf704194619d 127 SUPERFAMILY SSF54637 5 125 8.87E-29 T 29-03-2018 IPR029069 HotDog domain CSW12_RS24365 f0e0e3bc403eb4f303e6bf704194619d 127 Pfam PF03061 Thioesterase superfamily 35 113 6.8E-13 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS24365 f0e0e3bc403eb4f303e6bf704194619d 127 Gene3D G3DSA:3.10.129.10 1 127 1.2E-22 T 29-03-2018 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 Pfam PF13354 Beta-lactamase enzyme family 78 284 2.3E-37 T 29-03-2018 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 Gene3D G3DSA:3.40.710.10 56 308 1.5E-33 T 29-03-2018 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 SUPERFAMILY SSF56601 57 312 3.59E-77 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 244 259 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 89 106 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 191 216 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 227 242 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 58 82 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 129 154 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS11735 a1b2e3636a11c505e68b175b6a36443d 316 PRINTS PR00118 Beta-lactamase class A signature 165 189 2.7E-62 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 157 3.0E-39 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 SUPERFAMILY SSF53218 8 165 3.14E-45 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 PIRSF PIRSF006443 1 169 1.1E-69 T 29-03-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 Gene3D G3DSA:3.40.980.10 1 168 4.5E-35 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 Pfam PF00994 Probable molybdopterin binding domain 18 161 1.3E-38 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 SMART SM00852 17 162 1.9E-34 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS23505 22e7a8f5c31ae79e162f96a01653d4d0 169 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 29-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CSW12_RS27860 02a67f3d594fbb4efe827cb299e60370 158 Gene3D G3DSA:3.30.1330.50 1 158 2.7E-74 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CSW12_RS27860 02a67f3d594fbb4efe827cb299e60370 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 29-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CSW12_RS27860 02a67f3d594fbb4efe827cb299e60370 158 Pfam PF02542 YgbB family 2 156 8.6E-67 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CSW12_RS27860 02a67f3d594fbb4efe827cb299e60370 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.019 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CSW12_RS27860 02a67f3d594fbb4efe827cb299e60370 158 SUPERFAMILY SSF69765 1 157 3.79E-67 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CSW12_RS27860 02a67f3d594fbb4efe827cb299e60370 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 2.9E-73 T 29-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CSW12_RS25465 93bcbf956b112933ab8c32ec4b577a3f 317 Gene3D G3DSA:3.40.50.10680 86 317 2.6E-59 T 29-03-2018 CSW12_RS25465 93bcbf956b112933ab8c32ec4b577a3f 317 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 9 316 5.5E-124 T 29-03-2018 IPR010119 Gluconeogenesis factor CSW12_RS25465 93bcbf956b112933ab8c32ec4b577a3f 317 SUPERFAMILY SSF142338 6 314 1.7E-106 T 29-03-2018 CSW12_RS25465 93bcbf956b112933ab8c32ec4b577a3f 317 Hamap MF_00973 Gluconeogenesis factor. 5 312 33.992 T 29-03-2018 IPR010119 Gluconeogenesis factor CSW12_RS25465 93bcbf956b112933ab8c32ec4b577a3f 317 Pfam PF01933 Uncharacterised protein family UPF0052 9 292 4.9E-104 T 29-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CSW12_RS11725 9da5a9e2e8b2857a291b6d0846c729d8 703 Gene3D G3DSA:2.60.60.30 467 588 1.2E-13 T 29-03-2018 CSW12_RS00135 72b4aeb3e5a576fa2a18870e1de7d3fa 382 Pfam PF01757 Acyltransferase family 8 338 8.0E-38 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS17125 ad752e4b86aafc002da270a497dc5f3d 111 Gene3D G3DSA:2.40.50.140 1 110 5.2E-38 T 29-03-2018 CSW12_RS17125 ad752e4b86aafc002da270a497dc5f3d 111 Pfam PF00436 Single-strand binding protein family 2 103 7.6E-35 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CSW12_RS17125 ad752e4b86aafc002da270a497dc5f3d 111 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 106 4.2E-33 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS17125 ad752e4b86aafc002da270a497dc5f3d 111 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 32.174 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS17125 ad752e4b86aafc002da270a497dc5f3d 111 PIRSF PIRSF002070 1 111 4.9E-36 T 29-03-2018 CSW12_RS17125 ad752e4b86aafc002da270a497dc5f3d 111 SUPERFAMILY SSF50249 1 109 7.54E-41 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS12195 af74e23b20766fcb77bd226aaa3cd914 171 Pfam PF11553 Protein of unknown function (DUF3231) 2 167 5.2E-44 T 29-03-2018 IPR021617 Protein of unknown function DUF3231 CSW12_RS12195 af74e23b20766fcb77bd226aaa3cd914 171 Gene3D G3DSA:1.20.1260.10 1 157 1.4E-24 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS03510 c43abea61c68bd4760da65ded1267d39 114 Pfam PF00893 Small Multidrug Resistance protein 5 93 4.1E-15 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CSW12_RS03510 c43abea61c68bd4760da65ded1267d39 114 SUPERFAMILY SSF103481 8 105 2.09E-12 T 29-03-2018 CSW12_RS09305 264d32b85ec4c3ba8218eb7f70faca7d 79 Gene3D G3DSA:1.10.287.540 4 56 1.8E-22 T 29-03-2018 CSW12_RS09305 264d32b85ec4c3ba8218eb7f70faca7d 79 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 1.0E-27 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CSW12_RS09305 264d32b85ec4c3ba8218eb7f70faca7d 79 Hamap MF_01103 UPF0291 protein . 2 60 16.358 T 29-03-2018 IPR009242 Protein of unknown function DUF896 CSW12_RS09305 264d32b85ec4c3ba8218eb7f70faca7d 79 SUPERFAMILY SSF158221 1 42 2.35E-13 T 29-03-2018 CSW12_RS23870 64de4bbebdc4104128ab260ecadfce43 256 SMART SM00382 33 221 7.2E-9 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS23870 64de4bbebdc4104128ab260ecadfce43 256 Gene3D G3DSA:3.40.50.300 1 238 1.1E-63 T 29-03-2018 CSW12_RS23870 64de4bbebdc4104128ab260ecadfce43 256 Pfam PF00005 ABC transporter 24 172 1.2E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS23870 64de4bbebdc4104128ab260ecadfce43 256 SUPERFAMILY SSF52540 4 228 4.54E-69 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13940 71d1ae38cd66d1c6afef965b126deeeb 259 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 32 259 7.7E-102 T 29-03-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 CSW12_RS13940 71d1ae38cd66d1c6afef965b126deeeb 259 Gene3D G3DSA:1.10.101.10 28 105 2.1E-21 T 29-03-2018 IPR002477 Peptidoglycan binding-like CSW12_RS13940 71d1ae38cd66d1c6afef965b126deeeb 259 Pfam PF07486 Cell Wall Hydrolase 160 258 1.6E-28 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CSW12_RS13940 71d1ae38cd66d1c6afef965b126deeeb 259 Pfam PF01471 Putative peptidoglycan binding domain 43 99 2.0E-17 T 29-03-2018 IPR002477 Peptidoglycan binding-like CSW12_RS13940 71d1ae38cd66d1c6afef965b126deeeb 259 SUPERFAMILY SSF47090 34 100 2.62E-20 T 29-03-2018 IPR002477 Peptidoglycan binding-like CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 TIGRFAM TIGR00761 argB: acetylglutamate kinase 5 229 8.2E-73 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 SUPERFAMILY SSF53633 2 251 7.59E-64 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 Gene3D G3DSA:3.40.1160.10 2 255 1.1E-50 T 29-03-2018 CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 Pfam PF00696 Amino acid kinase family 5 231 3.4E-44 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 Hamap MF_00082_B Acetylglutamate kinase [argB]. 1 250 29.629 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 PRINTS PR01469 Bacterial carbamate kinase signature 31 50 5.0E-6 T 29-03-2018 CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 PRINTS PR01469 Bacterial carbamate kinase signature 155 170 5.0E-6 T 29-03-2018 CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 PRINTS PR01469 Bacterial carbamate kinase signature 204 219 5.0E-6 T 29-03-2018 CSW12_RS20200 9943ad7a39f8f135c0fffc82cfd6b133 255 PIRSF PIRSF000728 1 250 1.4E-86 T 29-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CSW12_RS17435 05d85716df4005857d1f84f2df379e9e 161 Gene3D G3DSA:3.40.630.30 1 161 2.9E-33 T 29-03-2018 CSW12_RS17435 05d85716df4005857d1f84f2df379e9e 161 SUPERFAMILY SSF55729 1 149 1.59E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17435 05d85716df4005857d1f84f2df379e9e 161 Pfam PF00583 Acetyltransferase (GNAT) family 42 137 1.0E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 SUPERFAMILY SSF81296 41 210 5.04E-57 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 SMART SM00495 409 455 2.1E-4 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 SUPERFAMILY SSF49265 219 403 2.64E-25 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 SUPERFAMILY SSF51055 407 441 4.97E-6 T 29-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 41 207 7.9E-39 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Gene3D G3DSA:2.10.10.20 412 455 9.3E-11 T 29-03-2018 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Gene3D G3DSA:2.60.40.10 302 401 6.9E-17 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Gene3D G3DSA:2.60.40.10 203 301 7.7E-18 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 SMART SM00060 220 293 2.0E-8 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 SMART SM00060 314 391 8.3E-7 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Pfam PF00041 Fibronectin type III domain 316 391 7.0E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Pfam PF00041 Fibronectin type III domain 221 297 5.7E-6 T 29-03-2018 IPR003961 Fibronectin type III GO:0005515 CSW12_RS10310 a57e7636a4eb5cbfce46fb403083303a 458 Gene3D G3DSA:2.70.50.50 41 202 1.4E-52 T 29-03-2018 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 Pfam PF00085 Thioredoxin 4 103 3.8E-30 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 29-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 Gene3D G3DSA:3.40.30.10 1 103 6.1E-35 T 29-03-2018 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 PIRSF PIRSF000077 1 104 2.9E-40 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 PRINTS PR00421 Thioredoxin family signature 28 37 7.7E-7 T 29-03-2018 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 PRINTS PR00421 Thioredoxin family signature 20 28 7.7E-7 T 29-03-2018 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 PRINTS PR00421 Thioredoxin family signature 68 79 7.7E-7 T 29-03-2018 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 103 3.6E-37 T 29-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CSW12_RS22200 c49277f17c7fb3b66ac2967b6765f737 104 SUPERFAMILY SSF52833 3 103 1.44E-35 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 Pfam PF07690 Major Facilitator Superfamily 13 341 7.6E-43 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 Gene3D G3DSA:1.20.1250.20 193 377 1.4E-24 T 29-03-2018 CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 PRINTS PR01035 Tetracycline resistance protein signature 18 34 3.6E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 PRINTS PR01035 Tetracycline resistance protein signature 159 179 3.6E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 PRINTS PR01035 Tetracycline resistance protein signature 131 153 3.6E-15 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 SUPERFAMILY SSF103473 1 379 2.75E-65 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS26640 2a919a266331959434e0ee3045bed559 387 Gene3D G3DSA:1.20.1250.20 6 192 3.3E-32 T 29-03-2018 CSW12_RS21725 064cb929d8987b8358931c556db63793 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.369 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CSW12_RS21725 064cb929d8987b8358931c556db63793 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 373 1.2E-184 T 29-03-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CSW12_RS21725 064cb929d8987b8358931c556db63793 379 Gene3D G3DSA:3.20.20.105 1 374 2.8E-160 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CSW12_RS21725 064cb929d8987b8358931c556db63793 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 373 1.3E-173 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CSW12_RS21725 064cb929d8987b8358931c556db63793 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 2.2E-92 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CSW12_RS21725 064cb929d8987b8358931c556db63793 379 SUPERFAMILY SSF51713 2 369 3.4E-161 T 29-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 SUPERFAMILY SSF52821 351 456 1.57E-30 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 SUPERFAMILY SSF52821 222 337 2.88E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 SUPERFAMILY SSF56281 3 244 4.48E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 SMART SM00849 4 182 2.0E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 Pfam PF00753 Metallo-beta-lactamase superfamily 7 162 8.3E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 Gene3D G3DSA:3.60.15.10 3 249 2.0E-36 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 Gene3D G3DSA:3.40.250.10 260 337 1.6E-8 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 Pfam PF00581 Rhodanese-like domain 368 449 6.2E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 SMART SM00450 358 453 2.4E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 SMART SM00450 255 350 12.0 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS29420 5ebb1b0d0660e92bf8af0234ff999660 456 Gene3D G3DSA:3.40.250.10 345 456 1.8E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10020 b1c68fb0a894868aa8147ec988e7e761 279 Pfam PF08445 FR47-like protein 212 272 4.1E-8 T 29-03-2018 IPR013653 FR47-like GO:0016747 CSW12_RS10020 b1c68fb0a894868aa8147ec988e7e761 279 Gene3D G3DSA:3.40.630.30 140 274 4.7E-13 T 29-03-2018 CSW12_RS10020 b1c68fb0a894868aa8147ec988e7e761 279 SUPERFAMILY SSF55729 143 271 2.34E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS00175 cb8e938177ba74ce3f1186c82fc21a62 109 SMART SM00530 8 63 2.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS00175 cb8e938177ba74ce3f1186c82fc21a62 109 Gene3D G3DSA:1.10.260.40 4 109 4.6E-22 T 29-03-2018 CSW12_RS00175 cb8e938177ba74ce3f1186c82fc21a62 109 SUPERFAMILY SSF47413 3 68 5.36E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS00175 cb8e938177ba74ce3f1186c82fc21a62 109 Pfam PF01381 Helix-turn-helix 9 63 1.2E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS12355 f8ea26fe0813ee29696e203141783a66 253 Gene3D G3DSA:3.40.50.150 41 198 6.1E-11 T 29-03-2018 CSW12_RS12355 f8ea26fe0813ee29696e203141783a66 253 Pfam PF08241 Methyltransferase domain 56 142 1.2E-6 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS12355 f8ea26fe0813ee29696e203141783a66 253 SUPERFAMILY SSF53335 26 190 2.7E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:3.30.450.20 33 167 3.4E-27 T 29-03-2018 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:3.30.565.10 379 534 3.1E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 511 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 477 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 517 530 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 491 4.7E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF55890 325 407 2.09E-9 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 324 368 1.2E-8 T 29-03-2018 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 428 532 1.2E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF17203 Single cache domain 3 40 170 8.3E-29 T 29-03-2018 IPR033463 Single cache domain 3 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:1.10.287.130 315 378 6.9E-15 T 29-03-2018 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 SMART SM00387 422 533 6.2E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Pfam PF00989 PAS fold 219 290 5.6E-7 T 29-03-2018 IPR013767 PAS fold GO:0006355 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 Gene3D G3DSA:3.30.450.20 219 314 3.3E-9 T 29-03-2018 CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF55785 210 311 1.43E-8 T 29-03-2018 IPR000014 PAS domain CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 SMART SM00091 216 283 0.0018 T 29-03-2018 IPR000014 PAS domain CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF55874 388 530 1.44E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS01505 2596b45788ac6bdd2b9c35fde7f50929 535 SUPERFAMILY SSF103190 39 169 2.51E-40 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 SUPERFAMILY SSF90123 11 325 4.71E-79 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 Pfam PF00664 ABC transporter transmembrane region 24 297 2.2E-45 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 Pfam PF00005 ABC transporter 359 508 3.6E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 SUPERFAMILY SSF52540 335 578 7.42E-88 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 SMART SM00382 368 560 1.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 Gene3D G3DSA:1.20.1560.10 2 327 2.4E-72 T 29-03-2018 CSW12_RS09355 7ecf31e624823d63249c141b5c6de8a2 587 Gene3D G3DSA:3.40.50.300 328 584 2.9E-78 T 29-03-2018 CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 Pfam PF07883 Cupin domain 109 174 2.8E-10 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 Gene3D G3DSA:2.60.120.10 77 184 8.9E-17 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 SUPERFAMILY SSF51182 57 184 8.69E-24 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 SMART SM00530 9 64 1.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 Pfam PF01381 Helix-turn-helix 10 61 7.5E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 SUPERFAMILY SSF47413 2 71 5.09E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS15345 3090225ebdd439cd5e843f2f7f652f15 184 Gene3D G3DSA:1.10.260.40 1 76 1.5E-17 T 29-03-2018 CSW12_RS30670 85b2a29e16f2ca891242f8b1ec398d50 603 Gene3D G3DSA:3.40.50.1110 397 603 2.6E-22 T 29-03-2018 CSW12_RS30670 85b2a29e16f2ca891242f8b1ec398d50 603 Pfam PF01757 Acyltransferase family 14 345 5.6E-25 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS30670 85b2a29e16f2ca891242f8b1ec398d50 603 SUPERFAMILY SSF52266 438 602 4.83E-16 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 SUPERFAMILY SSF103473 446 479 4.97E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 SUPERFAMILY SSF103473 247 418 4.97E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 SUPERFAMILY SSF103473 7 196 4.97E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 3.8E-6 T 29-03-2018 CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 3.8E-6 T 29-03-2018 CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 3.8E-6 T 29-03-2018 CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 Pfam PF07690 Major Facilitator Superfamily 18 408 3.5E-50 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 Gene3D G3DSA:1.20.1250.20 258 484 1.0E-27 T 29-03-2018 CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 Gene3D G3DSA:1.20.1250.20 3 199 1.7E-29 T 29-03-2018 CSW12_RS12020 b836d2915b8fc755bf67cb06b36a70ba 484 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 446 8.5E-116 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS08750 dddaad9234d1f2c253ed3e958c504785 299 Gene3D G3DSA:3.20.20.370 68 299 1.0E-53 T 29-03-2018 CSW12_RS08750 dddaad9234d1f2c253ed3e958c504785 299 Pfam PF01522 Polysaccharide deacetylase 106 224 9.5E-30 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS08750 dddaad9234d1f2c253ed3e958c504785 299 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 27 294 5.0E-151 T 29-03-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY CSW12_RS08750 dddaad9234d1f2c253ed3e958c504785 299 SUPERFAMILY SSF88713 78 294 1.96E-61 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS12205 a687b2c089ccac6fe6fbe9c32399f6cd 285 SMART SM00849 38 248 1.4E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12205 a687b2c089ccac6fe6fbe9c32399f6cd 285 Gene3D G3DSA:3.60.15.10 34 265 5.3E-30 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12205 a687b2c089ccac6fe6fbe9c32399f6cd 285 Pfam PF00753 Metallo-beta-lactamase superfamily 38 248 1.5E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12205 a687b2c089ccac6fe6fbe9c32399f6cd 285 SUPERFAMILY SSF56281 25 254 3.93E-42 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 353 362 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 203 225 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 302 329 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 100 111 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 351 360 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 360 371 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 284 295 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 146 162 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 330 345 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00359 B-class P450 signature 163 178 8.3E-56 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 Gene3D G3DSA:1.10.630.10 4 411 2.8E-81 T 29-03-2018 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 SUPERFAMILY SSF48264 21 411 3.8E-98 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 Pfam PF00067 Cytochrome P450 280 380 1.3E-22 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 Pfam PF00067 Cytochrome P450 195 271 5.3E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00385 P450 superfamily signature 249 266 2.5E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00385 P450 superfamily signature 284 295 2.5E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00385 P450 superfamily signature 351 360 2.5E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14610 3989185cd90d0c97316d72ba2a16e2a3 411 PRINTS PR00385 P450 superfamily signature 360 371 2.5E-6 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS30655 053deaf67ac21e717fad10aabe7f6795 267 PIRSF PIRSF019271 1 267 6.6E-102 T 29-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 CSW12_RS30655 053deaf67ac21e717fad10aabe7f6795 267 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 8 267 9.1E-95 T 29-03-2018 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 CSW12_RS30655 053deaf67ac21e717fad10aabe7f6795 267 Gene3D G3DSA:3.40.50.1000 41 208 1.4E-28 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS30655 053deaf67ac21e717fad10aabe7f6795 267 SUPERFAMILY SSF56784 53 246 4.93E-47 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS30655 053deaf67ac21e717fad10aabe7f6795 267 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 30 240 4.3E-51 T 29-03-2018 IPR005519 Acid phosphatase, class B-like CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 Gene3D G3DSA:3.60.150.10 1 390 3.4E-143 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 Pfam PF01264 Chorismate synthase 1 364 6.6E-125 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.992 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 PIRSF PIRSF001456 1 385 1.8E-131 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 370 3.0E-131 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 SUPERFAMILY SSF103263 1 389 7.06E-152 T 29-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS12910 fcd0e2ab6d1ab332c870773571602c4f 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 29-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 SUPERFAMILY SSF53850 143 302 2.23E-18 T 29-03-2018 CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 Pfam PF12727 PBP superfamily domain 98 282 2.0E-53 T 29-03-2018 IPR024370 PBP domain CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 SUPERFAMILY SSF46955 15 62 5.13E-6 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 Pfam PF12728 Helix-turn-helix domain 15 62 8.3E-16 T 29-03-2018 CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 Gene3D G3DSA:1.10.10.10 16 69 1.3E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 15 62 5.0E-20 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CSW12_RS28460 4a45386a330f715498e44edf8a5b5152 315 Gene3D G3DSA:3.40.190.10 166 258 1.9E-9 T 29-03-2018 CSW12_RS21350 f831c275688aa344cd4aa359b50acd40 216 Gene3D G3DSA:3.30.460.10 4 154 8.8E-39 T 29-03-2018 CSW12_RS21350 f831c275688aa344cd4aa359b50acd40 216 SUPERFAMILY SSF81301 11 202 1.05E-56 T 29-03-2018 CSW12_RS21350 f831c275688aa344cd4aa359b50acd40 216 SMART SM00954 50 173 7.8E-47 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CSW12_RS21350 f831c275688aa344cd4aa359b50acd40 216 Pfam PF04607 Region found in RelA / SpoT proteins 50 171 7.1E-39 T 29-03-2018 IPR007685 RelA/SpoT GO:0015969 CSW12_RS21350 f831c275688aa344cd4aa359b50acd40 216 Gene3D G3DSA:1.10.287.860 156 204 4.8E-18 T 29-03-2018 CSW12_RS02995 86ae2f5fbef8bff4780f685117c99394 270 Pfam PF08543 Phosphomethylpyrimidine kinase 13 259 1.7E-102 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CSW12_RS02995 86ae2f5fbef8bff4780f685117c99394 270 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 1.4E-109 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS02995 86ae2f5fbef8bff4780f685117c99394 270 SUPERFAMILY SSF53613 1 263 8.11E-86 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS02995 86ae2f5fbef8bff4780f685117c99394 270 Gene3D G3DSA:3.40.1190.20 1 269 6.5E-68 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS26965 b441203347c4cf31c2731c470a693db9 344 Pfam PF01594 AI-2E family transporter 16 333 1.2E-44 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 Gene3D G3DSA:1.10.287.130 237 317 6.7E-17 T 29-03-2018 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 SUPERFAMILY SSF158472 194 245 2.48E-11 T 29-03-2018 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 SMART SM00304 194 246 5.7E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 SMART SM00387 367 480 9.8E-35 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 SUPERFAMILY SSF47384 241 321 3.73E-18 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 SMART SM00388 254 321 5.3E-17 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 Pfam PF00672 HAMP domain 194 242 3.6E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 Gene3D G3DSA:3.30.565.10 328 480 6.2E-43 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 319 8.6E-16 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 433 3.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 458 3.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 3.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 477 3.0E-17 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 SUPERFAMILY SSF55874 310 476 4.32E-45 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23005 c59c2a2ee25cdb624c1051ef5b01f926 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 477 6.7E-27 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26740 90089b0f8d948b25848376fa4ba40ffd 122 Pfam PF04241 Protein of unknown function (DUF423) 18 104 1.6E-32 T 29-03-2018 IPR006696 Protein of unknown function DUF423 CSW12_RS26340 fd91fe82b749c9e0e0ec8011a675d45b 130 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 130 1.0E-47 T 29-03-2018 CSW12_RS26340 fd91fe82b749c9e0e0ec8011a675d45b 130 Pfam PF03899 ATP synthase I chain 11 109 5.6E-15 T 29-03-2018 IPR005598 ATP synthase protein I CSW12_RS14365 7f3a20e5d71c7e7fb1e7c31095fc1470 214 Pfam PF06966 Protein of unknown function (DUF1295) 80 206 4.3E-16 T 29-03-2018 IPR010721 Protein of unknown function DUF1295 CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 5.2E-132 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 267 1.2E-87 T 29-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 29-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.684 T 29-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 SUPERFAMILY SSF52096 5 267 6.4E-79 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 Gene3D G3DSA:3.90.226.10 2 211 2.7E-62 T 29-03-2018 CSW12_RS24015 1b6b8bd66b27c6baf1329e9484b04a71 272 Gene3D G3DSA:1.10.12.10 212 260 3.6E-15 T 29-03-2018 IPR014748 Crontonase, C-terminal CSW12_RS10270 d1f0cdf0526bdb46f3b419f06d5e0952 249 Pfam PF00483 Nucleotidyl transferase 2 241 6.0E-16 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS10270 d1f0cdf0526bdb46f3b419f06d5e0952 249 SUPERFAMILY SSF53448 1 245 6.53E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10270 d1f0cdf0526bdb46f3b419f06d5e0952 249 Gene3D G3DSA:3.90.550.10 1 248 2.0E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS22435 05c96a36d05c6e89d5290f8b0994519f 185 Gene3D G3DSA:1.10.3210.10 2 185 1.9E-13 T 29-03-2018 CSW12_RS22435 05c96a36d05c6e89d5290f8b0994519f 185 SUPERFAMILY SSF109604 19 137 4.85E-17 T 29-03-2018 CSW12_RS22435 05c96a36d05c6e89d5290f8b0994519f 185 Pfam PF01966 HD domain 26 135 6.2E-11 T 29-03-2018 IPR006674 HD domain CSW12_RS18800 e67100a9e15030928da3026faf9334fd 310 Pfam PF00072 Response regulator receiver domain 5 114 3.2E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS18800 e67100a9e15030928da3026faf9334fd 310 SMART SM00448 4 114 1.7E-15 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS18800 e67100a9e15030928da3026faf9334fd 310 SUPERFAMILY SSF52172 5 136 2.42E-22 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS18800 e67100a9e15030928da3026faf9334fd 310 Pfam PF08664 YcbB domain 161 299 9.8E-49 T 29-03-2018 IPR013972 YcbB domain CSW12_RS18800 e67100a9e15030928da3026faf9334fd 310 Gene3D G3DSA:3.40.50.2300 4 254 1.8E-21 T 29-03-2018 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 271 289 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 44 59 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 258 2.0E-70 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 Gene3D G3DSA:3.50.50.60 244 321 1.1E-9 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 Gene3D G3DSA:3.50.50.60 131 243 4.5E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 138 158 - T 29-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 SUPERFAMILY SSF51905 6 305 2.11E-57 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 Gene3D G3DSA:3.50.50.60 3 130 1.6E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 297 6.2E-50 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 10 308 8.1E-121 T 29-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.8E-37 T 29-03-2018 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.8E-37 T 29-03-2018 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.8E-37 T 29-03-2018 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 1.8E-37 T 29-03-2018 CSW12_RS25485 b0dbddcb2349b50fed39a60fef8f1ffe 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.8E-37 T 29-03-2018 CSW12_RS02130 7e6aa5df0ea9ebf747347cd64ca37140 131 SUPERFAMILY SSF88659 62 123 9.53E-9 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02130 7e6aa5df0ea9ebf747347cd64ca37140 131 Gene3D G3DSA:1.10.10.10 41 129 5.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16505 3d67d93a3e0efe43eea0981ff01629ea 232 SMART SM00882 11 222 5.0E-67 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CSW12_RS16505 3d67d93a3e0efe43eea0981ff01629ea 232 SUPERFAMILY SSF100950 10 224 1.56E-73 T 29-03-2018 CSW12_RS16505 3d67d93a3e0efe43eea0981ff01629ea 232 Gene3D G3DSA:3.40.1080.10 5 229 1.3E-74 T 29-03-2018 CSW12_RS16505 3d67d93a3e0efe43eea0981ff01629ea 232 Pfam PF01144 Coenzyme A transferase 13 220 3.1E-64 T 29-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CSW12_RS16505 3d67d93a3e0efe43eea0981ff01629ea 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 12 222 1.4E-60 T 29-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CSW12_RS12145 bcf6443dfd46250fa15c991f5931ec0b 214 Pfam PF00857 Isochorismatase family 14 165 1.4E-20 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS12145 bcf6443dfd46250fa15c991f5931ec0b 214 Gene3D G3DSA:3.40.50.850 1 209 7.9E-38 T 29-03-2018 CSW12_RS12145 bcf6443dfd46250fa15c991f5931ec0b 214 SUPERFAMILY SSF52499 4 203 7.06E-51 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS15835 c0389fda8fe57860f9ed34cc9544aee4 194 Pfam PF01810 LysE type translocator 13 193 4.1E-16 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS07115 0e931733fb90083e9e108410cc8b3ee4 297 Pfam PF14045 YIEGIA protein 8 288 1.3E-123 T 29-03-2018 IPR025918 YIEGIA protein CSW12_RS07115 0e931733fb90083e9e108410cc8b3ee4 297 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 281 4.0E-139 T 29-03-2018 CSW12_RS26885 15799c812c25bef5abc05ace22c608ab 369 Gene3D G3DSA:3.40.50.2000 179 348 1.0E-35 T 29-03-2018 CSW12_RS26885 15799c812c25bef5abc05ace22c608ab 369 Pfam PF13439 Glycosyltransferase Family 4 13 169 8.0E-20 T 29-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CSW12_RS26885 15799c812c25bef5abc05ace22c608ab 369 SUPERFAMILY SSF53756 40 366 4.4E-71 T 29-03-2018 CSW12_RS26885 15799c812c25bef5abc05ace22c608ab 369 Gene3D G3DSA:3.40.50.2000 1 178 1.4E-14 T 29-03-2018 CSW12_RS26885 15799c812c25bef5abc05ace22c608ab 369 Pfam PF00534 Glycosyl transferases group 1 180 328 8.2E-30 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS27640 76f5db152ace5102a3f86804bd045ab4 217 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 2.6E-23 T 29-03-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like CSW12_RS27640 76f5db152ace5102a3f86804bd045ab4 217 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 130 2.9E-47 T 29-03-2018 IPR014242 Spore cortex biosynthesis protein, YabQ CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 354 2.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 368 2.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 387 2.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 406 2.1E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 Pfam PF00512 His Kinase A (phospho-acceptor) domain 200 256 3.7E-8 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 Gene3D G3DSA:3.30.565.10 260 408 2.9E-39 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 406 2.5E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 SMART SM00387 302 408 7.2E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 SUPERFAMILY SSF55874 258 406 3.27E-38 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 Gene3D G3DSA:1.10.287.130 181 256 2.4E-9 T 29-03-2018 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 SUPERFAMILY SSF47384 191 257 4.71E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS00635 7e044821724f6f9cf9db6caedf6817f1 408 SMART SM00388 197 260 3.1E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS16945 b18c9806bdae519707109e2ccf82c171 220 Gene3D G3DSA:3.40.50.1000 74 218 1.8E-29 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16945 b18c9806bdae519707109e2ccf82c171 220 Gene3D G3DSA:3.40.50.1000 1 29 0.14 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16945 b18c9806bdae519707109e2ccf82c171 220 Gene3D G3DSA:1.10.150.240 30 73 1.2E-15 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS16945 b18c9806bdae519707109e2ccf82c171 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 4.1E-31 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16945 b18c9806bdae519707109e2ccf82c171 220 SUPERFAMILY SSF56784 1 212 3.1E-55 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16945 b18c9806bdae519707109e2ccf82c171 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 176 2.9E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 Pfam PF00700 Bacterial flagellin C-terminal helical region 181 264 3.4E-19 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 140 9.4E-35 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 SUPERFAMILY SSF64518 1 265 4.97E-73 T 29-03-2018 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 PRINTS PR00207 Flagellin signature 109 132 9.3E-15 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 PRINTS PR00207 Flagellin signature 35 52 9.3E-15 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 PRINTS PR00207 Flagellin signature 74 93 9.3E-15 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19285 f7117d29079c1ac5074ca3a7892437c7 266 Gene3D G3DSA:1.20.1330.10 38 237 2.7E-55 T 29-03-2018 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.4E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 Gene3D G3DSA:1.10.10.10 1 74 1.3E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 Gene3D G3DSA:3.40.640.10 149 355 1.3E-41 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 SUPERFAMILY SSF46785 3 80 3.86E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 Pfam PF00155 Aminotransferase class I and II 130 465 3.2E-35 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 SUPERFAMILY SSF53383 103 475 1.75E-95 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 SMART SM00345 13 72 3.8E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 1.0E-15 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS14325 726a9b529c24155923dcc7a0e4c4055e 477 Gene3D G3DSA:3.90.1150.10 356 477 3.9E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS08125 e6a7019f05aefed057314c7a852c3175 408 Pfam PF05636 HIGH Nucleotidyl Transferase 1 382 1.4E-136 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CSW12_RS08125 e6a7019f05aefed057314c7a852c3175 408 SUPERFAMILY SSF52374 175 233 6.44E-18 T 29-03-2018 CSW12_RS08125 e6a7019f05aefed057314c7a852c3175 408 SUPERFAMILY SSF52374 5 100 6.44E-18 T 29-03-2018 CSW12_RS08125 e6a7019f05aefed057314c7a852c3175 408 Hamap MF_01539 UPF0348 protein . 1 399 39.904 T 29-03-2018 IPR008513 Uncharacterised protein family UPF0348 CSW12_RS08125 e6a7019f05aefed057314c7a852c3175 408 Gene3D G3DSA:3.40.50.620 1 240 1.2E-57 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS01515 f682772cf44c3b601b474fdc5ac10b6e 434 Pfam PF03600 Citrate transporter 13 380 2.9E-52 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CSW12_RS01515 f682772cf44c3b601b474fdc5ac10b6e 434 TIGRFAM TIGR00784 citMHS: citrate transporter 1 434 2.3E-204 T 29-03-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 CSW12_RS30360 9ef8bbc4bef92cc2591afa58e40ca487 77 Pfam PF17209 Hfq protein 19 75 7.7E-18 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS30360 9ef8bbc4bef92cc2591afa58e40ca487 77 Gene3D G3DSA:2.30.30.100 17 77 6.5E-21 T 29-03-2018 CSW12_RS30360 9ef8bbc4bef92cc2591afa58e40ca487 77 SUPERFAMILY SSF50182 19 76 6.21E-15 T 29-03-2018 IPR010920 LSM domain CSW12_RS30360 9ef8bbc4bef92cc2591afa58e40ca487 77 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 18 75 7.6E-21 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS19040 45cc115f02ed4eaeccb2cfed95e498cf 368 Pfam PF13786 Domain of unknown function (DUF4179) 44 136 1.6E-18 T 29-03-2018 IPR025436 Domain of unknown function DUF4179 CSW12_RS19040 45cc115f02ed4eaeccb2cfed95e498cf 368 Gene3D G3DSA:2.60.40.1630 75 221 8.4E-28 T 29-03-2018 CSW12_RS19040 45cc115f02ed4eaeccb2cfed95e498cf 368 Gene3D G3DSA:2.60.40.1640 222 368 2.3E-31 T 29-03-2018 CSW12_RS29985 acd4fec6a584e4b18958613ec739ab60 111 SUPERFAMILY SSF141066 8 110 4.84E-25 T 29-03-2018 IPR018990 Proteinase inhibitor I42, chagasin CSW12_RS29985 acd4fec6a584e4b18958613ec739ab60 111 Pfam PF09394 Chagasin family peptidase inhibitor I42 23 107 3.4E-16 T 29-03-2018 IPR018990 Proteinase inhibitor I42, chagasin CSW12_RS18835 bd621ad6e4b96e9c8acafa8cd181da2f 381 Pfam PF12698 ABC-2 family transporter protein 19 369 2.6E-43 T 29-03-2018 CSW12_RS18835 bd621ad6e4b96e9c8acafa8cd181da2f 381 Gene3D G3DSA:3.40.1710.10 43 198 9.6E-16 T 29-03-2018 CSW12_RS02530 6ea6899fddd4ec3ecaef20a03b1a147c 801 Pfam PF13884 Chaperone of endosialidase 675 757 9.2E-10 T 29-03-2018 IPR030392 Intramolecular chaperone auto-processing domain CSW12_RS02530 6ea6899fddd4ec3ecaef20a03b1a147c 801 Gene3D G3DSA:1.10.10.10 661 793 6.2E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS02530 6ea6899fddd4ec3ecaef20a03b1a147c 801 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 27 346 2.7E-45 T 29-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CSW12_RS02530 6ea6899fddd4ec3ecaef20a03b1a147c 801 Pfam PF06605 Prophage endopeptidase tail 265 358 5.8E-10 T 29-03-2018 IPR010572 Prophage tail endopeptidase CSW12_RS02530 6ea6899fddd4ec3ecaef20a03b1a147c 801 Pfam PF06605 Prophage endopeptidase tail 41 212 3.0E-8 T 29-03-2018 IPR010572 Prophage tail endopeptidase CSW12_RS25080 3502bc59ef85beefad0500fb468784a2 389 Pfam PF04235 Protein of unknown function (DUF418) 224 376 1.1E-39 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:2.40.40.20 335 477 2.3E-40 T 29-03-2018 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 SUPERFAMILY SSF64484 5 1180 0.0 T 29-03-2018 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 760 5.4E-15 T 29-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 1.0E-88 T 29-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1180 0.0 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 5.9E-37 T 29-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 989 1.8E-52 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF04998 RNA polymerase Rpb1, domain 5 994 1128 4.6E-14 T 29-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 385 2.7E-9 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Pfam PF00623 RNA polymerase Rpb1, domain 2 381 474 2.8E-29 T 29-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Gene3D G3DSA:2.40.50.100 910 1028 3.0E-41 T 29-03-2018 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1191 18.721 T 29-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27945 052d573398daf0384d76189004d8becf 1203 SMART SM00663 224 503 1.8E-185 T 29-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CSW12_RS27320 ee1a1505489da0455f9724ef85dbd2e2 70 Gene3D G3DSA:3.10.290.10 1 70 8.2E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS27320 ee1a1505489da0455f9724ef85dbd2e2 70 SUPERFAMILY SSF55174 1 66 8.58E-19 T 29-03-2018 CSW12_RS27320 ee1a1505489da0455f9724ef85dbd2e2 70 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 4 62 6.6E-32 T 29-03-2018 IPR014330 RNA-binding S4-related,YaaA CSW12_RS27320 ee1a1505489da0455f9724ef85dbd2e2 70 Pfam PF13275 S4 domain 4 68 4.3E-28 T 29-03-2018 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 PIRSF PIRSF001619 4 332 3.7E-125 T 29-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 SMART SM00876 237 327 3.6E-35 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 TIGRFAM TIGR00433 bioB: biotin synthase 33 326 2.9E-121 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 Hamap MF_01694 Biotin synthase [bioB]. 21 328 40.537 T 29-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 SUPERFAMILY SSF102114 23 328 2.62E-74 T 29-03-2018 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 SMART SM00729 61 269 1.8E-35 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 Pfam PF04055 Radical SAM superfamily 70 226 1.9E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 237 326 3.2E-14 T 29-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CSW12_RS20120 dbb25c3899aace53aaafac7afe84c5df 332 Gene3D G3DSA:3.20.20.70 20 330 4.3E-49 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS05805 c3322efef3d28eed2157551e9761e6a5 162 Gene3D G3DSA:3.40.630.30 2 154 4.5E-12 T 29-03-2018 CSW12_RS05805 c3322efef3d28eed2157551e9761e6a5 162 SUPERFAMILY SSF55729 5 134 2.34E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS05805 c3322efef3d28eed2157551e9761e6a5 162 Pfam PF00583 Acetyltransferase (GNAT) family 45 134 4.8E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS20655 777c01642e2164bc49d16af4402c68d7 191 Gene3D G3DSA:1.10.10.60 1 38 9.7E-14 T 29-03-2018 CSW12_RS20655 777c01642e2164bc49d16af4402c68d7 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 49 4.0E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS20655 777c01642e2164bc49d16af4402c68d7 191 SUPERFAMILY SSF46689 2 63 2.28E-15 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS20655 777c01642e2164bc49d16af4402c68d7 191 Gene3D G3DSA:1.10.10.60 39 183 5.0E-8 T 29-03-2018 CSW12_RS20655 777c01642e2164bc49d16af4402c68d7 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 1.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS20655 777c01642e2164bc49d16af4402c68d7 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 1.2E-6 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 SMART SM00862 148 224 6.3E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 SUPERFAMILY SSF52172 2 169 3.08E-40 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 Gene3D G3DSA:3.40.50.2300 2 122 3.6E-35 T 29-03-2018 CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 Pfam PF00072 Response regulator receiver domain 4 114 8.1E-28 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.2E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 Gene3D G3DSA:1.10.10.10 123 228 5.3E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17985 dd446b631f30465a5286af2a8dd1416a 229 SMART SM00448 2 113 1.3E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 SUPERFAMILY SSF56601 57 311 1.58E-72 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 Pfam PF13354 Beta-lactamase enzyme family 79 284 1.5E-35 T 29-03-2018 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 Gene3D G3DSA:3.40.710.10 56 311 2.6E-32 T 29-03-2018 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 58 82 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 89 106 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 244 259 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 129 154 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 165 189 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 191 216 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS03880 ada65fb635e4a126976cf2ad733dd672 315 PRINTS PR00118 Beta-lactamase class A signature 227 242 1.6E-64 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS17230 f78c5c636894c1ae7f1bf16efc3e1eed 305 Pfam PF03547 Membrane transport protein 161 297 2.7E-12 T 29-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CSW12_RS00095 c9354deb3270cd025dc9738f13585945 281 SUPERFAMILY SSF117892 87 217 1.96E-12 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS00095 c9354deb3270cd025dc9738f13585945 281 SMART SM00244 49 214 3.1E-11 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS00095 c9354deb3270cd025dc9738f13585945 281 Pfam PF01145 SPFH domain / Band 7 family 53 228 1.3E-22 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Gene3D G3DSA:1.10.287.950 332 428 9.9E-13 T 29-03-2018 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Pfam PF00672 HAMP domain 307 354 8.8E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Gene3D G3DSA:3.30.450.20 175 286 3.1E-17 T 29-03-2018 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 SUPERFAMILY SSF103190 99 198 4.71E-7 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Pfam PF02743 Cache domain 40 269 2.1E-28 T 29-03-2018 IPR033479 Double Cache domain 1 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 SMART SM00283 388 663 1.3E-67 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 462 606 7.6E-37 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 SMART SM00304 307 359 2.1E-15 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 SUPERFAMILY SSF58104 394 663 1.01E-70 T 29-03-2018 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 SUPERFAMILY SSF58104 327 361 1.01E-70 T 29-03-2018 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 486 513 8.1E-22 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 409 438 8.1E-22 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 515 544 8.1E-22 T 29-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Gene3D G3DSA:3.30.450.20 29 174 3.8E-18 T 29-03-2018 CSW12_RS24860 bbe3ad83a50a8659e5f873f1347ae18d 666 Gene3D G3DSA:1.10.287.950 429 666 1.3E-49 T 29-03-2018 CSW12_RS14520 27f0aa439f96f2fcdeb6fcae0e8b2d86 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 29 9.8E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS14520 27f0aa439f96f2fcdeb6fcae0e8b2d86 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 8 31 2.9E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 Pfam PF00072 Response regulator receiver domain 4 113 6.6E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 SMART SM00448 2 112 1.6E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 Gene3D G3DSA:3.40.50.2300 1 116 4.0E-37 T 29-03-2018 CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 SUPERFAMILY SSF46894 120 221 5.67E-26 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 SUPERFAMILY SSF52172 1 120 4.98E-42 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 Gene3D G3DSA:1.10.10.10 117 223 2.5E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 4.1E-22 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS01640 9e559c2136f946ce2e2c24417b575460 223 SMART SM00862 143 220 1.0E-20 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS07190 69a0a66ef8908b29a258f52726cfe2ac 304 Gene3D G3DSA:3.20.20.100 1 302 2.6E-79 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS07190 69a0a66ef8908b29a258f52726cfe2ac 304 Pfam PF00248 Aldo/keto reductase family 15 295 1.3E-64 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS07190 69a0a66ef8908b29a258f52726cfe2ac 304 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.7E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07190 69a0a66ef8908b29a258f52726cfe2ac 304 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.7E-5 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS07190 69a0a66ef8908b29a258f52726cfe2ac 304 SUPERFAMILY SSF51430 1 298 4.19E-79 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS12240 16e16ee67036859e1f26744432197eba 171 SUPERFAMILY SSF55729 8 159 1.18E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12240 16e16ee67036859e1f26744432197eba 171 Gene3D G3DSA:3.40.630.30 1 168 2.3E-22 T 29-03-2018 CSW12_RS12240 16e16ee67036859e1f26744432197eba 171 Pfam PF00583 Acetyltransferase (GNAT) family 52 153 3.4E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS09510 5c852ebcb8427f2cde2525bf6a0d2676 158 Pfam PF02559 CarD-like/TRCF domain 7 115 1.8E-17 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS09510 5c852ebcb8427f2cde2525bf6a0d2676 158 SUPERFAMILY SSF141259 7 63 2.75E-12 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS09510 5c852ebcb8427f2cde2525bf6a0d2676 158 SMART SM01058 6 116 1.7E-30 T 29-03-2018 IPR003711 CarD-like/TRCF domain CSW12_RS19840 3555b30e96660bb2b451cd88f23cbc85 200 TIGRFAM TIGR00648 recU: recombination protein U 29 196 1.8E-77 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CSW12_RS19840 3555b30e96660bb2b451cd88f23cbc85 200 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 200 102.001 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CSW12_RS19840 3555b30e96660bb2b451cd88f23cbc85 200 Gene3D G3DSA:3.40.1350.10 31 197 9.1E-63 T 29-03-2018 CSW12_RS19840 3555b30e96660bb2b451cd88f23cbc85 200 PIRSF PIRSF037785 22 200 1.0E-76 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CSW12_RS19840 3555b30e96660bb2b451cd88f23cbc85 200 Pfam PF03838 Recombination protein U 30 195 8.8E-68 T 29-03-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 CSW12_RS19840 3555b30e96660bb2b451cd88f23cbc85 200 SUPERFAMILY SSF52980 32 198 2.01E-67 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS03640 3f08291cc14a71f8a314ee3f10758fa3 485 Gene3D G3DSA:3.30.470.20 292 424 4.4E-12 T 29-03-2018 CSW12_RS03640 3f08291cc14a71f8a314ee3f10758fa3 485 Pfam PF14398 YheC/D like ATP-grasp 188 442 1.2E-82 T 29-03-2018 IPR026838 Endospore coat-associated protein YheC/D CSW12_RS03640 3f08291cc14a71f8a314ee3f10758fa3 485 SUPERFAMILY SSF56059 212 420 2.52E-12 T 29-03-2018 CSW12_RS03640 3f08291cc14a71f8a314ee3f10758fa3 485 Gene3D G3DSA:3.30.1490.20 218 291 1.3E-8 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 Gene3D G3DSA:1.10.10.10 2 107 5.4E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 Pfam PF12840 Helix-turn-helix domain 9 67 5.4E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 SMART SM00418 9 87 2.0E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 2.8E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.8E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 2.8E-10 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS23235 fa5a26b8313c25be9c95db8e1df9cf93 107 SUPERFAMILY SSF46785 8 93 4.96E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 Gene3D G3DSA:1.10.10.60 275 327 0.058 T 29-03-2018 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 Gene3D G3DSA:1.10.10.60 5 50 4.1E-5 T 29-03-2018 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 SUPERFAMILY SSF55608 161 253 5.44E-16 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 Gene3D G3DSA:3.10.28.10 68 167 7.9E-20 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 Pfam PF14528 LAGLIDADG-like domain 169 237 2.9E-6 T 29-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 Pfam PF14528 LAGLIDADG-like domain 78 144 8.8E-7 T 29-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 SUPERFAMILY SSF55608 76 145 2.13E-10 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS14245 d7b41cc72f9687efe072aa5a63ad20ca 331 Gene3D G3DSA:3.10.28.10 168 264 1.7E-12 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS00065 bfe3bbb97a46ac4584a5d01f0c4677d8 195 Pfam PF00551 Formyl transferase 3 182 5.0E-61 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS00065 bfe3bbb97a46ac4584a5d01f0c4677d8 195 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS00065 bfe3bbb97a46ac4584a5d01f0c4677d8 195 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 32.327 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CSW12_RS00065 bfe3bbb97a46ac4584a5d01f0c4677d8 195 SUPERFAMILY SSF53328 3 187 4.58E-62 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS00065 bfe3bbb97a46ac4584a5d01f0c4677d8 195 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 189 2.3E-72 T 29-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CSW12_RS00065 bfe3bbb97a46ac4584a5d01f0c4677d8 195 Gene3D G3DSA:3.40.50.170 2 194 5.0E-67 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS00580 a416d0d0389bc0dbff54a1dbcddd7c78 338 Pfam PF01032 FecCD transport family 25 332 2.2E-84 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS00580 a416d0d0389bc0dbff54a1dbcddd7c78 338 SUPERFAMILY SSF81345 8 332 8.89E-79 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS00580 a416d0d0389bc0dbff54a1dbcddd7c78 338 Gene3D G3DSA:1.10.3470.10 9 337 4.3E-59 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 SMART SM00382 344 513 3.1 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 SMART SM00382 26 228 1.9E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 Gene3D G3DSA:3.40.50.300 1 286 8.4E-57 T 29-03-2018 CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 SUPERFAMILY SSF52540 2 92 1.33E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 SUPERFAMILY SSF52540 125 255 1.33E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 Pfam PF12848 ABC transporter 224 300 1.8E-19 T 29-03-2018 IPR032781 ABC-transporter extension domain CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 Gene3D G3DSA:3.40.50.300 287 540 7.6E-39 T 29-03-2018 CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 SUPERFAMILY SSF52540 296 529 3.63E-37 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 Pfam PF00005 ABC transporter 335 468 1.2E-14 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS12945 887025aaa7847f5fb82fe9fcab4d1040 541 Pfam PF00005 ABC transporter 18 184 1.3E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS12250 54e7d1039e40ff00016a1ca2de0922d3 442 Pfam PF07670 Nucleoside recognition 136 229 5.0E-8 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS14790 605e45520a20b5df1aff06f6e9914258 209 Gene3D G3DSA:3.40.50.150 20 206 3.4E-25 T 29-03-2018 CSW12_RS14790 605e45520a20b5df1aff06f6e9914258 209 Pfam PF08241 Methyltransferase domain 40 133 1.3E-16 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS14790 605e45520a20b5df1aff06f6e9914258 209 SUPERFAMILY SSF53335 2 196 8.52E-35 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS04880 b5f7fe2936bbff34b2dbcfca0d49ded1 439 Gene3D G3DSA:3.30.2010.10 220 302 4.1E-18 T 29-03-2018 CSW12_RS04880 b5f7fe2936bbff34b2dbcfca0d49ded1 439 Pfam PF01435 Peptidase family M48 225 431 4.4E-36 T 29-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CSW12_RS04880 b5f7fe2936bbff34b2dbcfca0d49ded1 439 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 61 220 6.9E-22 T 29-03-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 SMART SM00448 2 115 1.5E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 Gene3D G3DSA:3.40.50.2300 1 126 1.7E-36 T 29-03-2018 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 Pfam PF00072 Response regulator receiver domain 4 116 1.8E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 SMART SM00421 147 204 1.0E-24 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.3E-14 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 Gene3D G3DSA:1.10.10.10 127 213 2.3E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 SUPERFAMILY SSF52172 1 133 1.42E-35 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.9E-21 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS15255 01629ff9b45a4c6055a9299d53bc3c87 213 SUPERFAMILY SSF46894 138 210 1.02E-22 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS17895 7443adaa76f044381f33af28e31e3661 46 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 18 40 5.3E-8 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS17895 7443adaa76f044381f33af28e31e3661 46 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 16 38 8.8E-10 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 ProSitePatterns PS00812 Glycosyl hydrolases family 8 signature. 181 199 - T 29-03-2018 IPR019834 Glycoside hydrolase, family 8, conserved site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 SUPERFAMILY SSF48208 51 433 1.36E-105 T 29-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 Gene3D G3DSA:1.50.10.10 53 436 8.6E-95 T 29-03-2018 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 244 261 8.6E-31 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 412 426 8.6E-31 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 287 298 8.6E-31 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 316 325 8.6E-31 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 181 199 8.6E-31 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 PRINTS PR00735 Glycosyl hydrolase family 8 signature 119 132 8.6E-31 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS14315 17809da4ea99e8df67d3cc0f21cc234c 453 Pfam PF01270 Glycosyl hydrolases family 8 82 424 1.2E-28 T 29-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CSW12_RS21840 83aa2c3d3931b294369ee17b909cd430 182 SMART SM01317 59 171 2.2E-61 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal CSW12_RS21840 83aa2c3d3931b294369ee17b909cd430 182 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 5 56 2.8E-17 T 29-03-2018 CSW12_RS21840 83aa2c3d3931b294369ee17b909cd430 182 Gene3D G3DSA:1.10.287.130 1 55 1.6E-13 T 29-03-2018 CSW12_RS21840 83aa2c3d3931b294369ee17b909cd430 182 Gene3D G3DSA:3.30.565.30 59 171 1.7E-36 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal CSW12_RS21840 83aa2c3d3931b294369ee17b909cd430 182 SUPERFAMILY SSF55890 2 173 2.09E-62 T 29-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CSW12_RS21840 83aa2c3d3931b294369ee17b909cd430 182 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 60 169 5.3E-37 T 29-03-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 SUPERFAMILY SSF50341 7 150 1.44E-34 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 Pfam PF01584 CheW-like domain 18 149 4.1E-36 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 Pfam PF00072 Response regulator receiver domain 176 296 4.7E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 Gene3D G3DSA:2.40.50.180 34 97 1.2E-17 T 29-03-2018 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 Gene3D G3DSA:2.30.30.40 98 143 7.2E-12 T 29-03-2018 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 Gene3D G3DSA:3.40.50.2300 165 301 1.6E-21 T 29-03-2018 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 PIRSF PIRSF002867 1 302 1.8E-94 T 29-03-2018 IPR024181 Chemotaxis response regulator CheV CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 SMART SM00448 174 297 9.0E-20 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 SUPERFAMILY SSF52172 173 300 2.28E-23 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS19295 c59f30705ac12442f96c595aa03c63bb 302 SMART SM00260 13 149 1.5E-29 T 29-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CSW12_RS14120 be3d64bd3d0507dbbf013d9c02a52042 217 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 151 205 3.2E-16 T 29-03-2018 CSW12_RS07880 e0e3385e4bfbe220de26761c939ec53f 371 Gene3D G3DSA:3.40.50.970 4 339 5.3E-84 T 29-03-2018 CSW12_RS07880 e0e3385e4bfbe220de26761c939ec53f 371 SUPERFAMILY SSF52518 18 366 3.34E-101 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS07880 e0e3385e4bfbe220de26761c939ec53f 371 Pfam PF00676 Dehydrogenase E1 component 53 343 1.1E-102 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CSW12_RS07880 e0e3385e4bfbe220de26761c939ec53f 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 25 364 1.6E-141 T 29-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CSW12_RS00830 dee32c99cfe7ce5fc795395319730de7 123 Pfam PF09350 Domain of unknown function (DUF1992) 7 73 1.7E-24 T 29-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain CSW12_RS27020 deea55d731febe6b3126cef37b74277c 196 Pfam PF02293 AmiS/UreI family transporter 1 164 2.1E-49 T 29-03-2018 IPR003211 AmiS/UreI transporter GO:0006810|GO:0016020 CSW12_RS19205 ee78f186f5dd9d0128fbd3c89e30ce1e 432 Gene3D G3DSA:3.20.20.30 15 430 2.0E-79 T 29-03-2018 CSW12_RS19205 ee78f186f5dd9d0128fbd3c89e30ce1e 432 PIRSF PIRSF000337 13 430 4.0E-116 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CSW12_RS19205 ee78f186f5dd9d0128fbd3c89e30ce1e 432 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 23 420 8.4E-104 T 29-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CSW12_RS19205 ee78f186f5dd9d0128fbd3c89e30ce1e 432 Pfam PF00296 Luciferase-like monooxygenase 26 376 7.9E-55 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CSW12_RS19205 ee78f186f5dd9d0128fbd3c89e30ce1e 432 SUPERFAMILY SSF51679 27 424 9.55E-94 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CSW12_RS13925 675cd323ab8774c9b3d4969af37bf92b 286 Pfam PF00144 Beta-lactamase 18 263 2.9E-23 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS13925 675cd323ab8774c9b3d4969af37bf92b 286 Gene3D G3DSA:3.40.710.10 5 281 8.8E-45 T 29-03-2018 CSW12_RS13925 675cd323ab8774c9b3d4969af37bf92b 286 SUPERFAMILY SSF56601 4 276 5.0E-64 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 1.1E-115 T 29-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 5.4E-24 T 29-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 5.2E-112 T 29-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 Gene3D G3DSA:3.30.930.10 8 344 1.4E-94 T 29-03-2018 CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.957 T 29-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 SUPERFAMILY SSF55681 93 342 1.49E-83 T 29-03-2018 CSW12_RS22420 7414121f63dbf68542820c5e1a72d4f3 344 SUPERFAMILY SSF46589 16 100 1.15E-21 T 29-03-2018 IPR010978 tRNA-binding arm GO:0000166 CSW12_RS05450 d3d2bfc0912599badb6314bd699a9e76 338 SUPERFAMILY SSF161098 129 318 2.22E-31 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS05450 d3d2bfc0912599badb6314bd699a9e76 338 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 32 83 2.6E-14 T 29-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CSW12_RS05450 d3d2bfc0912599badb6314bd699a9e76 338 Gene3D G3DSA:1.10.3720.10 32 326 5.0E-50 T 29-03-2018 CSW12_RS05450 d3d2bfc0912599badb6314bd699a9e76 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 154 338 2.5E-32 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS04705 c9fac33a9c17fe55e08eda784501c8f4 133 Gene3D G3DSA:1.10.10.10 9 72 6.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04705 c9fac33a9c17fe55e08eda784501c8f4 133 Pfam PF03965 Penicillinase repressor 8 123 3.1E-39 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CSW12_RS04705 c9fac33a9c17fe55e08eda784501c8f4 133 PIRSF PIRSF019455 1 133 4.5E-40 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CSW12_RS04705 c9fac33a9c17fe55e08eda784501c8f4 133 Gene3D G3DSA:1.10.4040.10 74 123 1.3E-15 T 29-03-2018 CSW12_RS04705 c9fac33a9c17fe55e08eda784501c8f4 133 SUPERFAMILY SSF46785 6 126 4.89E-35 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 175 4.6E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 SUPERFAMILY SSF88946 3 104 5.49E-15 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 Gene3D G3DSA:1.10.10.10 106 180 6.7E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 Gene3D G3DSA:1.10.1740.10 1 105 7.5E-14 T 29-03-2018 CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 Pfam PF04542 Sigma-70 region 2 22 91 7.3E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 SUPERFAMILY SSF88659 116 176 6.54E-15 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS22250 a1b33dbe49ea3e99bfad0dc56926a978 181 Pfam PF08281 Sigma-70, region 4 123 171 3.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS14195 4a23f5805fad612cb7d75f24a5696681 173 Gene3D G3DSA:1.20.120.450 1 173 2.8E-38 T 29-03-2018 CSW12_RS14195 4a23f5805fad612cb7d75f24a5696681 173 Pfam PF12867 DinB superfamily 32 164 3.8E-13 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS14195 4a23f5805fad612cb7d75f24a5696681 173 Hamap MF_01256 Putative metal-dependent hydrolase . 2 173 40.834 T 29-03-2018 IPR023774 Putative metal-dependent hydrolase YfiT CSW12_RS14195 4a23f5805fad612cb7d75f24a5696681 173 SUPERFAMILY SSF109854 3 173 3.05E-49 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS08090 d89a3646407c2398f79168e5a1ca6d89 88 PIRSF PIRSF031653 1 88 1.8E-34 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CSW12_RS08090 d89a3646407c2398f79168e5a1ca6d89 88 Hamap MF_01126 UPF0298 protein . 1 78 23.278 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CSW12_RS08090 d89a3646407c2398f79168e5a1ca6d89 88 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 8.0E-30 T 29-03-2018 IPR016979 Protein of unknown function DUF2129 CSW12_RS01060 dd55f590da302589997fe14bccb25204 473 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS01060 dd55f590da302589997fe14bccb25204 473 Pfam PF00324 Amino acid permease 16 450 1.2E-127 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS01060 dd55f590da302589997fe14bccb25204 473 PIRSF PIRSF006060 1 469 8.5E-85 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS23465 5c7768566535e2cd53cf4c9fa5c00334 433 Pfam PF03929 PepSY-associated TM region 12 376 1.9E-57 T 29-03-2018 IPR005625 PepSY-associated TM protein CSW12_RS23465 5c7768566535e2cd53cf4c9fa5c00334 433 Gene3D G3DSA:1.20.950.20 148 254 0.0072 T 29-03-2018 CSW12_RS23465 5c7768566535e2cd53cf4c9fa5c00334 433 Gene3D G3DSA:1.20.1300.10 321 425 0.0067 T 29-03-2018 CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 PIRSF PIRSF039004 1 366 1.0E-136 T 29-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 Gene3D G3DSA:2.30.40.10 2 65 3.7E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 Gene3D G3DSA:3.20.20.140 66 314 4.9E-42 T 29-03-2018 CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 SUPERFAMILY SSF51338 5 52 1.09E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 SUPERFAMILY SSF51338 317 363 1.09E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 SUPERFAMILY SSF51556 52 316 1.03E-65 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS23965 54c8aebf59298c771f03559af88f22c1 366 TIGRFAM TIGR03583 EF_0837: putative amidohydrolase, EF_0837/AHA_3915 family 4 364 7.2E-174 T 29-03-2018 IPR020043 Amidohydrolase EF0837/AHA3915, putative CSW12_RS18200 437958eecae393e73d105937625f7ca1 233 Gene3D G3DSA:3.40.50.300 1 233 9.1E-54 T 29-03-2018 CSW12_RS18200 437958eecae393e73d105937625f7ca1 233 SMART SM00382 28 217 7.0E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS18200 437958eecae393e73d105937625f7ca1 233 Pfam PF00005 ABC transporter 19 161 6.5E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18200 437958eecae393e73d105937625f7ca1 233 SUPERFAMILY SSF52540 3 229 3.22E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18200 437958eecae393e73d105937625f7ca1 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS07255 ce14c503ec36cc81bedb1bb89c3b864d 429 Pfam PF00860 Permease family 20 387 2.2E-32 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 2.2E-5 T 29-03-2018 CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 2.3E-70 T 29-03-2018 CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.4E-46 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 3.7E-106 T 29-03-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 SUPERFAMILY SSF51735 3 246 9.23E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 6.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 6.6E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 Gene3D G3DSA:3.40.50.720 44 246 2.5E-71 T 29-03-2018 CSW12_RS08520 efdbbc674d67ad91ba70d0376a7472ae 246 Gene3D G3DSA:3.40.50.10090 1 43 1.1E-10 T 29-03-2018 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 Gene3D G3DSA:2.60.15.10 1 88 6.9E-29 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 Gene3D G3DSA:1.20.5.440 89 131 5.3E-18 T 29-03-2018 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 23.023 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 2.0E-38 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 SUPERFAMILY SSF51344 2 83 3.01E-24 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 SUPERFAMILY SSF46604 87 131 5.75E-10 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 129 9.9E-38 T 29-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 7.5E-30 T 29-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26295 0f28386e791370a749c3bfe6449aa904 133 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 130 1.2E-14 T 29-03-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS28520 7a21afb117a48d32e68fbb031627fd99 118 Pfam PF06486 Protein of unknown function (DUF1093) 33 102 2.0E-12 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS28520 7a21afb117a48d32e68fbb031627fd99 118 SUPERFAMILY SSF159121 31 114 1.57E-19 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS28520 7a21afb117a48d32e68fbb031627fd99 118 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 3 114 1.3E-15 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS12570 e25e02186840010abd804dbbd8b16243 388 Pfam PF00144 Beta-lactamase 60 371 3.9E-65 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS12570 e25e02186840010abd804dbbd8b16243 388 Gene3D G3DSA:3.40.710.10 42 385 3.7E-78 T 29-03-2018 CSW12_RS12570 e25e02186840010abd804dbbd8b16243 388 SUPERFAMILY SSF56601 53 377 5.78E-80 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS10105 8ada05cba5c84487b5262b4ea23b081f 172 Pfam PF13302 Acetyltransferase (GNAT) domain 21 150 2.7E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS10105 8ada05cba5c84487b5262b4ea23b081f 172 SUPERFAMILY SSF55729 3 153 3.19E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS10105 8ada05cba5c84487b5262b4ea23b081f 172 Gene3D G3DSA:3.40.630.30 1 159 1.4E-14 T 29-03-2018 CSW12_RS20300 7b945f28e221a96dc8b11e2e42216753 181 Gene3D G3DSA:3.40.630.30 1 181 5.6E-17 T 29-03-2018 CSW12_RS20300 7b945f28e221a96dc8b11e2e42216753 181 SUPERFAMILY SSF55729 1 179 1.78E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS20300 7b945f28e221a96dc8b11e2e42216753 181 Pfam PF13302 Acetyltransferase (GNAT) domain 9 155 1.8E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS25105 1d007135a05228158c2ddd49919ce782 212 Pfam PF13460 NAD(P)H-binding 7 198 1.1E-23 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS25105 1d007135a05228158c2ddd49919ce782 212 SUPERFAMILY SSF51735 1 209 1.22E-31 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS25105 1d007135a05228158c2ddd49919ce782 212 Gene3D G3DSA:3.40.50.720 1 209 2.1E-19 T 29-03-2018 CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 SUPERFAMILY SSF101801 27 103 3.79E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 30 99 9.9E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 Gene3D G3DSA:2.30.330.10 17 111 1.7E-17 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 27 102 3.8E-25 T 29-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 76 91 1.1E-10 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 63 76 1.1E-10 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 47 63 1.1E-10 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19250 0bd5c29327b8e56ae90f9879a2a5c5ca 119 PRINTS PR00956 Flagellar motor switch protein FliN signature 30 46 1.1E-10 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS03285 156564295267b1b3465690eb6b360305 362 Gene3D G3DSA:2.40.100.10 244 359 4.0E-44 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS03285 156564295267b1b3465690eb6b360305 362 SUPERFAMILY SSF50891 246 358 1.02E-40 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS03285 156564295267b1b3465690eb6b360305 362 Pfam PF05913 Bacterial protein of unknown function (DUF871) 3 358 2.0E-147 T 29-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CSW12_RS03285 156564295267b1b3465690eb6b360305 362 Gene3D G3DSA:3.20.20.70 3 238 6.3E-98 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS03285 156564295267b1b3465690eb6b360305 362 SUPERFAMILY SSF51445 1 242 9.69E-96 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS24065 30edfdb8cb76c8ac16072a300a9cc196 240 Gene3D G3DSA:3.40.50.1820 2 239 6.4E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS24065 30edfdb8cb76c8ac16072a300a9cc196 240 Pfam PF01764 Lipase (class 3) 66 196 1.7E-29 T 29-03-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 CSW12_RS24065 30edfdb8cb76c8ac16072a300a9cc196 240 SUPERFAMILY SSF53474 6 218 5.2E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS25785 272d2179ced5a2f866866aa9033c3036 378 Gene3D G3DSA:3.40.50.150 135 376 3.9E-40 T 29-03-2018 CSW12_RS25785 272d2179ced5a2f866866aa9033c3036 378 Pfam PF01564 Spermine/spermidine synthase domain 137 311 2.8E-34 T 29-03-2018 CSW12_RS25785 272d2179ced5a2f866866aa9033c3036 378 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 158 171 - T 29-03-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS25785 272d2179ced5a2f866866aa9033c3036 378 SUPERFAMILY SSF53335 102 320 5.52E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS25785 272d2179ced5a2f866866aa9033c3036 378 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 87 346 26.232 T 29-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CSW12_RS05860 72aede96f46238788bcf998ca491c58e 60 Pfam PF13121 Domain of unknown function (DUF3976) 17 56 9.7E-30 T 29-03-2018 IPR025008 Domain of unknown function DUF3976 CSW12_RS24985 fcb3673e5de75800ba6bf7ac40778a70 272 Gene3D G3DSA:3.40.50.150 2 253 4.0E-24 T 29-03-2018 CSW12_RS24985 fcb3673e5de75800ba6bf7ac40778a70 272 Pfam PF08241 Methyltransferase domain 66 155 5.9E-13 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS24985 fcb3673e5de75800ba6bf7ac40778a70 272 SUPERFAMILY SSF53335 27 241 2.92E-28 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS06940 5ec723e67dc336eddaec62283b41fa1b 198 Pfam PF07670 Nucleoside recognition 43 150 8.2E-10 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS18605 033e3cc13dce7825812772701d9dab51 79 Pfam PF13710 ACT domain 15 76 2.1E-14 T 29-03-2018 CSW12_RS18605 033e3cc13dce7825812772701d9dab51 79 SUPERFAMILY SSF55021 6 77 1.91E-14 T 29-03-2018 CSW12_RS18605 033e3cc13dce7825812772701d9dab51 79 Gene3D G3DSA:3.30.70.260 3 79 1.8E-11 T 29-03-2018 CSW12_RS18605 033e3cc13dce7825812772701d9dab51 79 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 79 2.0E-38 T 29-03-2018 CSW12_RS21230 5c489e4d264c01bd08c7a9b61280b174 85 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 2.1E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21230 5c489e4d264c01bd08c7a9b61280b174 85 SUPERFAMILY SSF46992 3 85 3.01E-28 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21230 5c489e4d264c01bd08c7a9b61280b174 85 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.83 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21230 5c489e4d264c01bd08c7a9b61280b174 85 Gene3D G3DSA:1.20.58.110 1 85 1.5E-27 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21230 5c489e4d264c01bd08c7a9b61280b174 85 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 84 6.0E-33 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS21230 5c489e4d264c01bd08c7a9b61280b174 85 Pfam PF01649 Ribosomal protein S20 2 84 8.0E-26 T 29-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS01790 4a5fa3217d2fec199523dc18e3ada0bf 334 SUPERFAMILY SSF81345 5 329 2.22E-81 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS01790 4a5fa3217d2fec199523dc18e3ada0bf 334 Gene3D G3DSA:1.10.3470.10 4 334 3.8E-63 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS01790 4a5fa3217d2fec199523dc18e3ada0bf 334 Pfam PF01032 FecCD transport family 20 329 5.3E-93 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS27440 973b83198b3d4cb3635a1ac8b87858d4 109 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 7 101 23.631 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CSW12_RS27440 973b83198b3d4cb3635a1ac8b87858d4 109 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 108 3.0E-33 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CSW12_RS27440 973b83198b3d4cb3635a1ac8b87858d4 109 SUPERFAMILY SSF82607 13 106 3.27E-34 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CSW12_RS27440 973b83198b3d4cb3635a1ac8b87858d4 109 PIRSF PIRSF004555 5 109 1.2E-39 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CSW12_RS27440 973b83198b3d4cb3635a1ac8b87858d4 109 Pfam PF02575 YbaB/EbfC DNA-binding family 13 103 4.0E-35 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CSW12_RS27440 973b83198b3d4cb3635a1ac8b87858d4 109 Gene3D G3DSA:3.30.1310.10 1 109 2.7E-39 T 29-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CSW12_RS26690 432554064e1120368c82987504362b24 338 SUPERFAMILY SSF81345 7 336 1.06E-86 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS26690 432554064e1120368c82987504362b24 338 Pfam PF01032 FecCD transport family 21 336 7.8E-96 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS26690 432554064e1120368c82987504362b24 338 Gene3D G3DSA:1.10.3470.10 5 338 5.0E-68 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 Gene3D G3DSA:3.60.40.10 145 380 7.7E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 SMART SM00448 1 122 4.4E-35 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 Pfam PF00072 Response regulator receiver domain 3 122 8.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 190 377 2.4E-38 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 SMART SM00331 163 377 4.4E-24 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 SUPERFAMILY SSF81606 179 376 1.41E-7 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 SUPERFAMILY SSF52172 2 156 2.56E-36 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS04305 17ceb6d51499211e478460ed60346d2b 380 Gene3D G3DSA:3.40.50.2300 1 144 5.3E-37 T 29-03-2018 CSW12_RS22460 eb51b37efb2b3d33a14f18f0df4c6ecb 217 Gene3D G3DSA:2.40.50.100 41 118 9.2E-8 T 29-03-2018 CSW12_RS22460 eb51b37efb2b3d33a14f18f0df4c6ecb 217 Pfam PF13437 HlyD family secretion protein 94 207 1.2E-13 T 29-03-2018 CSW12_RS22460 eb51b37efb2b3d33a14f18f0df4c6ecb 217 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 205 217 6.6E-5 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CSW12_RS22460 eb51b37efb2b3d33a14f18f0df4c6ecb 217 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 134 158 6.6E-5 T 29-03-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CSW12_RS02170 72a83312e96190a613a124f32d4049d9 260 Pfam PF00574 Clp protease 39 174 1.9E-30 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CSW12_RS02170 72a83312e96190a613a124f32d4049d9 260 Gene3D G3DSA:3.90.226.10 13 175 2.1E-28 T 29-03-2018 CSW12_RS02170 72a83312e96190a613a124f32d4049d9 260 SUPERFAMILY SSF52096 15 178 2.95E-44 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS02170 72a83312e96190a613a124f32d4049d9 260 PRINTS PR00127 Clp protease catalytic subunit P signature 151 170 5.2E-8 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS02170 72a83312e96190a613a124f32d4049d9 260 PRINTS PR00127 Clp protease catalytic subunit P signature 44 64 5.2E-8 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS02170 72a83312e96190a613a124f32d4049d9 260 PRINTS PR00127 Clp protease catalytic subunit P signature 75 92 5.2E-8 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS29405 b192770e9ad807a63484bc841abfc5d0 190 Pfam PF00589 Phage integrase family 29 176 5.3E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS29405 b192770e9ad807a63484bc841abfc5d0 190 SUPERFAMILY SSF56349 13 187 2.47E-35 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS29405 b192770e9ad807a63484bc841abfc5d0 190 Gene3D G3DSA:1.10.443.10 10 190 4.3E-32 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 SUPERFAMILY SSF53850 88 281 1.01E-35 T 29-03-2018 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 Gene3D G3DSA:3.40.190.10 85 164 2.0E-14 T 29-03-2018 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 Gene3D G3DSA:1.10.10.10 1 83 1.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 Gene3D G3DSA:3.40.190.10 165 256 1.5E-14 T 29-03-2018 CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 SUPERFAMILY SSF46785 2 110 5.44E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 Pfam PF03466 LysR substrate binding domain 88 280 1.5E-40 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS10430 2b22e18cc730e7d072e1e0c92b186039 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 SMART SM00861 4 179 1.7E-69 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 SUPERFAMILY SSF52922 188 325 1.19E-40 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Gene3D G3DSA:3.40.50.970 2 194 4.8E-74 T 29-03-2018 CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 6.5E-52 T 29-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 SUPERFAMILY SSF52518 2 204 7.5E-74 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Gene3D G3DSA:3.40.50.920 195 326 9.7E-36 T 29-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CSW12_RS20375 8fb8cc959fbe0c6fb85202b8dbb74f83 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.7E-41 T 29-03-2018 IPR033248 Transketolase, C-terminal domain CSW12_RS02605 3fef7117605c82d6cc4be41def86f01d 95 Gene3D G3DSA:3.30.70.100 1 92 1.9E-6 T 29-03-2018 CSW12_RS02605 3fef7117605c82d6cc4be41def86f01d 95 SUPERFAMILY SSF54909 1 79 2.24E-12 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS28375 8fe3613897c42467a22f9f3c168c2eed 71 Pfam PF13131 Protein of unknown function (DUF3951) 4 52 2.1E-23 T 29-03-2018 IPR025028 Protein of unknown function DUF3951 CSW12_RS20350 5b1b633befa6c0da9c39f022c47397f6 154 Gene3D G3DSA:3.90.79.10 1 152 1.2E-29 T 29-03-2018 CSW12_RS20350 5b1b633befa6c0da9c39f022c47397f6 154 SUPERFAMILY SSF55811 7 147 2.03E-31 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS20350 5b1b633befa6c0da9c39f022c47397f6 154 PRINTS PR00502 NUDIX hydrolase family signature 44 58 2.2E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS20350 5b1b633befa6c0da9c39f022c47397f6 154 PRINTS PR00502 NUDIX hydrolase family signature 58 73 2.2E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS20350 5b1b633befa6c0da9c39f022c47397f6 154 Pfam PF00293 NUDIX domain 20 143 8.5E-23 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS20350 5b1b633befa6c0da9c39f022c47397f6 154 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS01540 0bdef0c81052e332135a92c45eac6c50 188 Gene3D G3DSA:3.20.20.400 1 179 2.5E-58 T 29-03-2018 CSW12_RS01540 0bdef0c81052e332135a92c45eac6c50 188 SUPERFAMILY SSF110391 5 178 3.53E-50 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CSW12_RS01540 0bdef0c81052e332135a92c45eac6c50 188 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 7 178 3.0E-56 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CSW12_RS01540 0bdef0c81052e332135a92c45eac6c50 188 PIRSF PIRSF016897 1 184 7.0E-70 T 29-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CSW12_RS00475 01d991b1bf29ff6f6b4cd57c51cbba00 360 Gene3D G3DSA:3.20.20.370 19 354 3.6E-27 T 29-03-2018 CSW12_RS00475 01d991b1bf29ff6f6b4cd57c51cbba00 360 SUPERFAMILY SSF88713 162 332 6.39E-27 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS00475 01d991b1bf29ff6f6b4cd57c51cbba00 360 Pfam PF01522 Polysaccharide deacetylase 195 316 9.7E-17 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS22405 535e836f8a9419583c69995969e33793 44 Pfam PF14115 YuzL-like protein 4 43 1.1E-13 T 29-03-2018 IPR025625 YuzL-like protein CSW12_RS30370 50f04d055fa12b96999e9970400d70a6 54 SUPERFAMILY SSF140500 7 52 2.22E-9 T 29-03-2018 CSW12_RS30370 50f04d055fa12b96999e9970400d70a6 54 Pfam PF09388 Spo0E like sporulation regulatory protein 9 50 1.4E-5 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CSW12_RS09030 735a1ee762ac7fda0db2d38dc662622c 328 SUPERFAMILY SSF51735 1 258 1.04E-56 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS09030 735a1ee762ac7fda0db2d38dc662622c 328 Gene3D G3DSA:3.40.50.720 2 326 1.7E-58 T 29-03-2018 CSW12_RS09030 735a1ee762ac7fda0db2d38dc662622c 328 Pfam PF02719 Polysaccharide biosynthesis protein 6 279 8.0E-105 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CSW12_RS11440 a6aa6f81239fd184865530d8fcae3e83 448 Pfam PF02667 Short chain fatty acid transporter 4 447 1.3E-164 T 29-03-2018 IPR006160 Short chain fatty acid transporter AtoE CSW12_RS30060 9b59d52c4e8350e934df703a5e177512 993 Pfam PF01526 Tn3 transposase DDE domain 583 968 8.9E-142 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 CSW12_RS30060 9b59d52c4e8350e934df703a5e177512 993 Pfam PF13700 Domain of unknown function (DUF4158) 7 172 2.4E-52 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 406 463 7.0E-10 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 224 238 - T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 Gene3D G3DSA:3.90.100.10 375 493 6.4E-35 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 9 372 6.2E-114 T 29-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 Gene3D G3DSA:3.40.640.10 9 287 5.3E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 SUPERFAMILY SSF53383 9 388 2.15E-97 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS07935 c117e85fb51ee360cbbcb193fb2caf8f 493 SUPERFAMILY SSF55904 345 488 1.96E-39 T 29-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CSW12_RS18195 b4610e07ca402150dc49d5e04424e59f 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 1.4E-36 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS18195 b4610e07ca402150dc49d5e04424e59f 286 Gene3D G3DSA:1.10.3470.10 1 277 4.2E-42 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS09320 7c1e2dc1a6449b8688a7f35a9e92ed32 257 Pfam PF00005 ABC transporter 18 174 1.5E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09320 7c1e2dc1a6449b8688a7f35a9e92ed32 257 SUPERFAMILY SSF52540 1 237 2.24E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09320 7c1e2dc1a6449b8688a7f35a9e92ed32 257 Gene3D G3DSA:3.40.50.300 1 253 5.0E-60 T 29-03-2018 CSW12_RS09320 7c1e2dc1a6449b8688a7f35a9e92ed32 257 SMART SM00382 27 223 1.0E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS09320 7c1e2dc1a6449b8688a7f35a9e92ed32 257 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 243 1.8E-107 T 29-03-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CSW12_RS09320 7c1e2dc1a6449b8688a7f35a9e92ed32 257 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25250 1053b89cb9310cbc8f0f96bf4fa0db9e 193 Gene3D G3DSA:3.40.1050.10 1 192 4.3E-33 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS25250 1053b89cb9310cbc8f0f96bf4fa0db9e 193 Pfam PF00484 Carbonic anhydrase 32 177 2.0E-12 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS25250 1053b89cb9310cbc8f0f96bf4fa0db9e 193 SMART SM00947 25 182 5.4E-26 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS25250 1053b89cb9310cbc8f0f96bf4fa0db9e 193 SUPERFAMILY SSF53056 3 181 2.09E-35 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS14645 af2508b977779ad3bc23065041814ea8 803 Pfam PF13111 Protein of unknown function (DUF3962) 13 224 7.6E-108 T 29-03-2018 IPR025085 Domain of unknown function DUF3962 CSW12_RS14645 af2508b977779ad3bc23065041814ea8 803 Pfam PF13032 Domain of unknown function (DUF3893) 666 773 2.8E-18 T 29-03-2018 IPR024996 Domain of unknown function DUF3893 CSW12_RS04945 c6bc3ee18c9eb699efb0e6186139fb07 193 Pfam PF06338 ComK protein 10 159 7.8E-57 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CSW12_RS04945 c6bc3ee18c9eb699efb0e6186139fb07 193 PIRSF PIRSF011560 4 192 1.6E-70 T 29-03-2018 IPR010461 Competence protein ComK GO:0030420 CSW12_RS13355 7e13b808133f263c58c87fc537c48d6d 224 Gene3D G3DSA:3.40.50.1000 2 219 5.0E-23 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS13355 7e13b808133f263c58c87fc537c48d6d 224 SUPERFAMILY SSF56784 1 216 1.6E-39 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS13355 7e13b808133f263c58c87fc537c48d6d 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 179 8.4E-15 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07945 e238803fb19c017596aa5d48bd058e10 208 PIRSF PIRSF021332 1 208 7.9E-95 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CSW12_RS07945 e238803fb19c017596aa5d48bd058e10 208 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 1.0E-85 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CSW12_RS07945 e238803fb19c017596aa5d48bd058e10 208 SUPERFAMILY SSF142913 3 206 5.23E-83 T 29-03-2018 CSW12_RS07945 e238803fb19c017596aa5d48bd058e10 208 Hamap MF_01851 UPF0637 protein . 5 205 39.443 T 29-03-2018 IPR009403 Protein of unknown function UPF0637 CSW12_RS25030 88d533b09755ca798e6afb5192501a1b 399 Gene3D G3DSA:1.20.91.10 234 311 3.5E-7 T 29-03-2018 CSW12_RS25030 88d533b09755ca798e6afb5192501a1b 399 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 2.9E-63 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CSW12_RS20420 45799689541330f97c623f3d3fb4de33 242 SUPERFAMILY SSF51695 1 237 1.15E-72 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS20420 45799689541330f97c623f3d3fb4de33 242 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 233 1.1E-42 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CSW12_RS20420 45799689541330f97c623f3d3fb4de33 242 Gene3D G3DSA:3.20.20.190 1 242 1.1E-68 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS09270 8aa5855df8f7d507612735144aa915bf 129 Gene3D G3DSA:1.10.1660.10 1 121 1.6E-22 T 29-03-2018 CSW12_RS09270 8aa5855df8f7d507612735144aa915bf 129 Pfam PF13411 MerR HTH family regulatory protein 13 76 3.7E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS09270 8aa5855df8f7d507612735144aa915bf 129 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS09270 8aa5855df8f7d507612735144aa915bf 129 SMART SM00422 11 79 6.8E-24 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS09270 8aa5855df8f7d507612735144aa915bf 129 SUPERFAMILY SSF46955 11 90 3.85E-18 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS05485 59038877d1194df950fb301fd0153a94 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 8.9E-35 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CSW12_RS05485 59038877d1194df950fb301fd0153a94 131 SUPERFAMILY SSF52833 1 129 3.3E-38 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS05485 59038877d1194df950fb301fd0153a94 131 Gene3D G3DSA:3.40.30.10 1 131 2.2E-36 T 29-03-2018 CSW12_RS05485 59038877d1194df950fb301fd0153a94 131 Pfam PF03960 ArsC family 5 113 9.4E-21 T 29-03-2018 IPR006660 Arsenate reductase-like CSW12_RS05485 59038877d1194df950fb301fd0153a94 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 37.166 T 29-03-2018 IPR023731 Regulatory protein Spx GO:0045892 CSW12_RS12755 175178f165e4a27873be7e84903f1291 397 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 79 2.0E-19 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS12755 175178f165e4a27873be7e84903f1291 397 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 395 1.8E-48 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS04825 53b5cab0a048871242d615649555cf40 325 SUPERFAMILY SSF109604 3 259 5.61E-46 T 29-03-2018 CSW12_RS04825 53b5cab0a048871242d615649555cf40 325 SMART SM00471 45 159 7.3E-8 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS04825 53b5cab0a048871242d615649555cf40 325 Gene3D G3DSA:1.10.3210.10 1 252 1.0E-37 T 29-03-2018 CSW12_RS04825 53b5cab0a048871242d615649555cf40 325 Pfam PF01966 HD domain 49 120 1.1E-8 T 29-03-2018 IPR006674 HD domain CSW12_RS06265 b3081e5dfa8576ac9b6e738d75225a55 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 27 138 9.9E-57 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CSW12_RS06265 b3081e5dfa8576ac9b6e738d75225a55 165 PIRSF PIRSF027377 8 147 6.8E-63 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CSW12_RS06265 b3081e5dfa8576ac9b6e738d75225a55 165 SUPERFAMILY SSF55620 27 134 2.89E-28 T 29-03-2018 CSW12_RS06265 b3081e5dfa8576ac9b6e738d75225a55 165 Gene3D G3DSA:3.30.1130.10 21 165 4.3E-41 T 29-03-2018 CSW12_RS06265 b3081e5dfa8576ac9b6e738d75225a55 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 72.226 T 29-03-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CSW12_RS06265 b3081e5dfa8576ac9b6e738d75225a55 165 Pfam PF14489 QueF-like protein 62 140 8.9E-36 T 29-03-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CSW12_RS05220 827b38d4813fb680e718caee74227a87 865 SUPERFAMILY SSF75005 206 401 1.73E-11 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CSW12_RS05220 827b38d4813fb680e718caee74227a87 865 Gene3D G3DSA:2.115.10.20 104 203 1.1E-4 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CSW12_RS05220 827b38d4813fb680e718caee74227a87 865 Gene3D G3DSA:2.115.10.20 204 341 3.6E-6 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CSW12_RS05220 827b38d4813fb680e718caee74227a87 865 Gene3D G3DSA:2.115.10.20 342 429 0.001 T 29-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CSW12_RS08555 e8b4fd42a7bab738b66bda14ed8e2e08 90 Pfam PF00886 Ribosomal protein S16 9 67 1.2E-26 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08555 e8b4fd42a7bab738b66bda14ed8e2e08 90 SUPERFAMILY SSF54565 2 86 2.62E-35 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08555 e8b4fd42a7bab738b66bda14ed8e2e08 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 29-03-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08555 e8b4fd42a7bab738b66bda14ed8e2e08 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.495 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08555 e8b4fd42a7bab738b66bda14ed8e2e08 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.0E-35 T 29-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08555 e8b4fd42a7bab738b66bda14ed8e2e08 90 Gene3D G3DSA:3.30.1320.10 2 85 2.1E-35 T 29-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 SUPERFAMILY SSF53649 310 508 8.73E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 SUPERFAMILY SSF53649 2 76 8.73E-76 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 3 508 2.2E-211 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 81 298 9.1E-85 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 3 509 49.851 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 PIRSF PIRSF001492 1 509 3.0E-205 T 29-03-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 Gene3D G3DSA:3.40.720.10 298 509 1.8E-35 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 SUPERFAMILY SSF64158 76 309 1.83E-92 T 29-03-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 Gene3D G3DSA:3.40.1450.10 76 297 1.4E-98 T 29-03-2018 CSW12_RS25345 9a2e220805fde27577e83fa32eb55341 509 Pfam PF01676 Metalloenzyme superfamily 3 497 6.2E-77 T 29-03-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CSW12_RS24755 0588c09980c3f893c2951ed36ae8637b 114 SMART SM00493 5 79 1.8E-5 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS24755 0588c09980c3f893c2951ed36ae8637b 114 Gene3D G3DSA:3.40.1360.20 1 113 2.2E-15 T 29-03-2018 CSW12_RS24755 0588c09980c3f893c2951ed36ae8637b 114 SUPERFAMILY SSF110455 1 111 5.75E-33 T 29-03-2018 CSW12_RS17195 b1ea3d3d16f59bf93001b87e4c7ac479 235 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 231 9.7E-86 T 29-03-2018 IPR019903 Repair of iron centres family CSW12_RS17195 b1ea3d3d16f59bf93001b87e4c7ac479 235 Gene3D G3DSA:1.20.120.520 67 234 2.5E-30 T 29-03-2018 CSW12_RS17195 b1ea3d3d16f59bf93001b87e4c7ac479 235 Pfam PF04405 Domain of Unknown function (DUF542) 9 61 2.7E-21 T 29-03-2018 IPR019903 Repair of iron centres family CSW12_RS17195 b1ea3d3d16f59bf93001b87e4c7ac479 235 Gene3D G3DSA:1.10.3910.10 1 65 3.7E-15 T 29-03-2018 CSW12_RS17195 b1ea3d3d16f59bf93001b87e4c7ac479 235 Pfam PF01814 Hemerythrin HHE cation binding domain 84 231 6.1E-26 T 29-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CSW12_RS23825 f4aaf9a980f3ce834109d4ff0028fb9b 300 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 7 293 2.6E-79 T 29-03-2018 IPR005218 Diacylglycerol/lipid kinase CSW12_RS23825 f4aaf9a980f3ce834109d4ff0028fb9b 300 Pfam PF00781 Diacylglycerol kinase catalytic domain 8 130 8.6E-35 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CSW12_RS23825 f4aaf9a980f3ce834109d4ff0028fb9b 300 SUPERFAMILY SSF111331 6 297 4.71E-74 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CSW12_RS23825 f4aaf9a980f3ce834109d4ff0028fb9b 300 SMART SM00046 8 134 4.7E-15 T 29-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CSW12_RS23825 f4aaf9a980f3ce834109d4ff0028fb9b 300 Gene3D G3DSA:3.40.50.10330 1 135 5.3E-33 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CSW12_RS25565 0d4ccfdb5d058247e0d17804f09f4c61 352 Pfam PF03601 Conserved hypothetical protein 698 29 330 3.2E-84 T 29-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 2.3E-56 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 Gene3D G3DSA:1.10.540.10 1 120 6.8E-41 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 1.7E-25 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 SUPERFAMILY SSF56645 2 243 1.1E-87 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 Gene3D G3DSA:1.20.140.10 219 379 4.7E-64 T 29-03-2018 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 SUPERFAMILY SSF47203 229 378 4.49E-61 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 5.2E-39 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 PIRSF PIRSF016578 2 378 1.7E-23 T 29-03-2018 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS15035 b32a536e603869c8bb18d86166ef6e7c 381 Gene3D G3DSA:2.40.110.10 121 218 2.5E-38 T 29-03-2018 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 SUPERFAMILY SSF46689 141 184 3.59E-5 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 Gene3D G3DSA:1.10.10.60 134 171 6.1E-12 T 29-03-2018 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 Pfam PF02796 Helix-turn-helix domain of resolvase 142 183 2.0E-6 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 SUPERFAMILY SSF53041 5 138 2.22E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 Gene3D G3DSA:3.40.50.1390 1 109 4.6E-36 T 29-03-2018 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 Gene3D G3DSA:1.20.5.40 110 133 1.0E-17 T 29-03-2018 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 Pfam PF00239 Resolvase, N terminal domain 5 139 2.6E-43 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 Gene3D G3DSA:1.10.1660.10 172 234 0.0011 T 29-03-2018 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 ProSitePatterns PS00397 Site-specific recombinases active site. 8 16 - T 29-03-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CSW12_RS30320 5cbaa842be02144891465893e57076ab 290 SMART SM00857 5 139 1.1E-54 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS18660 ee0697044c15101603fd7bbbb769c043 87 SUPERFAMILY SSF46689 1 85 1.16E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS18660 ee0697044c15101603fd7bbbb769c043 87 Gene3D G3DSA:1.10.10.60 44 87 1.1E-11 T 29-03-2018 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 183 195 1.2E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 268 287 1.2E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 PRINTS PR00410 Phenol hydroxylase reductase family signature 363 371 1.2E-8 T 29-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Gene3D G3DSA:3.40.50.80 259 401 1.3E-26 T 29-03-2018 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Gene3D G3DSA:2.40.30.10 158 258 3.8E-26 T 29-03-2018 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Pfam PF00042 Globin 7 103 2.4E-10 T 29-03-2018 IPR000971 Globin GO:0020037 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Pfam PF00970 Oxidoreductase FAD-binding domain 156 257 8.2E-10 T 29-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Hamap MF_01252 Flavohemoprotein [hmp]. 1 401 58.554 T 29-03-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 SUPERFAMILY SSF46458 2 141 1.83E-41 T 29-03-2018 IPR009050 Globin-like CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Pfam PF00175 Oxidoreductase NAD-binding domain 269 376 7.2E-18 T 29-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 SUPERFAMILY SSF52343 262 398 3.01E-36 T 29-03-2018 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 SUPERFAMILY SSF63380 149 259 2.89E-31 T 29-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CSW12_RS06830 7f5c4d94f90da339fcce7070c974b9d5 402 Gene3D G3DSA:1.10.490.10 1 157 3.2E-43 T 29-03-2018 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 Pfam PF01025 GrpE 25 188 3.0E-55 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 Gene3D G3DSA:2.30.22.10 132 188 1.0E-21 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 ProSitePatterns PS01071 grpE protein signature. 143 186 - T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 SUPERFAMILY SSF51064 133 188 4.58E-19 T 29-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 SUPERFAMILY SSF58014 38 132 7.32E-26 T 29-03-2018 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 Hamap MF_01151 Protein GrpE [grpE]. 2 188 21.368 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 Gene3D G3DSA:3.90.20.20 1 130 1.3E-25 T 29-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 58 74 1.3E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 86 101 1.3E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 140 155 1.3E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS21195 6007ac0640b5e40a826e697faeed7680 188 PRINTS PR00773 GrpE protein signature 167 186 1.3E-30 T 29-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 1.0E-8 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 SUPERFAMILY SSF46785 21 140 7.26E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 Pfam PF01047 MarR family 33 89 1.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 SMART SM00347 25 125 1.2E-25 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12535 9653a126e8fdebcaebbad60586780ddb 142 Gene3D G3DSA:1.10.10.10 3 142 2.3E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27500 09923b7b50e1a960367e36c4e93eb9c2 327 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 17 198 5.1E-62 T 29-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS27500 09923b7b50e1a960367e36c4e93eb9c2 327 Gene3D G3DSA:3.40.50.300 11 157 6.7E-30 T 29-03-2018 CSW12_RS27500 09923b7b50e1a960367e36c4e93eb9c2 327 SUPERFAMILY SSF52540 11 205 1.68E-43 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27500 09923b7b50e1a960367e36c4e93eb9c2 327 Gene3D G3DSA:1.20.272.10 209 327 6.5E-23 T 29-03-2018 CSW12_RS27500 09923b7b50e1a960367e36c4e93eb9c2 327 Pfam PF13177 DNA polymerase III, delta subunit 13 170 3.0E-56 T 29-03-2018 CSW12_RS27500 09923b7b50e1a960367e36c4e93eb9c2 327 Gene3D G3DSA:1.10.8.60 158 208 4.0E-7 T 29-03-2018 CSW12_RS12980 350ca36cdaad36a466e49736c52ca4a9 129 Gene3D G3DSA:3.10.180.10 6 129 3.3E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12980 350ca36cdaad36a466e49736c52ca4a9 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 122 5.8E-10 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS12980 350ca36cdaad36a466e49736c52ca4a9 129 SUPERFAMILY SSF54593 6 125 1.09E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS00975 b2c3f668921ae088cb34d5e2741dd74e 920 Gene3D G3DSA:1.25.40.10 10 91 0.0038 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS00975 b2c3f668921ae088cb34d5e2741dd74e 920 SUPERFAMILY SSF48452 40 168 3.67E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS00975 b2c3f668921ae088cb34d5e2741dd74e 920 Gene3D G3DSA:1.25.40.10 92 172 1.2E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS00975 b2c3f668921ae088cb34d5e2741dd74e 920 Gene3D G3DSA:3.40.50.300 379 751 2.2E-7 T 29-03-2018 CSW12_RS00975 b2c3f668921ae088cb34d5e2741dd74e 920 SUPERFAMILY SSF52540 377 578 2.26E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 437 529 1.4E-16 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 482 499 - T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 Pfam PF02378 Phosphotransferase system, EIIC 13 377 8.6E-57 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 Pfam PF00367 phosphotransferase system, EIIB 472 499 4.0E-14 T 29-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 2 545 0.0 T 29-03-2018 IPR011300 Phosphotransferase system, IIBC component KEGG: 00010+2.7.1.199|KEGG: 00520+2.7.1.199|KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 Gene3D G3DSA:3.30.1360.60 468 543 9.1E-23 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS00745 506de531c568a896ba232e89a9136f17 545 SUPERFAMILY SSF55604 469 544 2.09E-19 T 29-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 PRINTS PR01693 Cyanase signature 134 144 2.9E-23 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 PRINTS PR01693 Cyanase signature 101 117 2.9E-23 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 PRINTS PR01693 Cyanase signature 14 29 2.9E-23 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 PRINTS PR01693 Cyanase signature 34 51 2.9E-23 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 PRINTS PR01693 Cyanase signature 83 97 2.9E-23 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 TIGRFAM TIGR00673 cynS: cyanase 6 149 1.0E-44 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 PIRSF PIRSF001263 1 149 1.6E-44 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 SMART SM01116 75 149 5.4E-31 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 Gene3D G3DSA:1.10.260.40 1 79 6.3E-7 T 29-03-2018 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 Gene3D G3DSA:3.30.1160.10 81 148 4.6E-28 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 Pfam PF02560 Cyanate lyase C-terminal domain 79 147 4.9E-27 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 Hamap MF_00535 Cyanate hydratase [cynS]. 1 149 65.379 T 29-03-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 SUPERFAMILY SSF55234 79 149 3.27E-22 T 29-03-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00400+4.2.1.10|KEGG: 00910+4.2.1.104|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CSW12_RS25255 37b8fbd8c509dc16ad90cc77d9cdda6e 149 SUPERFAMILY SSF47413 1 75 5.63E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS18300 b905f7900943a2d7ed49b7b19fe91892 230 Pfam PF02525 Flavodoxin-like fold 25 225 7.4E-41 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS18300 b905f7900943a2d7ed49b7b19fe91892 230 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 24 230 27.948 T 29-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CSW12_RS18300 b905f7900943a2d7ed49b7b19fe91892 230 Gene3D G3DSA:3.40.50.360 24 230 9.3E-34 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS18300 b905f7900943a2d7ed49b7b19fe91892 230 SUPERFAMILY SSF52218 23 230 5.03E-47 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 Gene3D G3DSA:1.10.287.890 203 283 3.1E-29 T 29-03-2018 CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 SUPERFAMILY SSF52540 10 163 2.92E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 303 30.305 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 SUPERFAMILY SSF52540 11 41 6.91E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 SUPERFAMILY SSF52540 142 232 6.91E-5 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 294 8.8E-114 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 Gene3D G3DSA:3.40.50.300 5 198 1.9E-70 T 29-03-2018 CSW12_RS09230 8c9ab606e6121e08e18ffdc945418987 317 Pfam PF01715 IPP transferase 42 286 5.2E-83 T 29-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CSW12_RS22700 4104ae30367c046766f3eeb12f8f944b 121 Gene3D G3DSA:2.40.50.140 37 118 8.8E-21 T 29-03-2018 CSW12_RS22700 4104ae30367c046766f3eeb12f8f944b 121 Pfam PF11518 Protein of unknown function (DUF3221) 14 119 1.6E-41 T 29-03-2018 IPR021598 Protein of unknown function DUF3221 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.2E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.2E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.2E-11 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 Pfam PF03466 LysR substrate binding domain 91 292 2.4E-50 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 SUPERFAMILY SSF53850 93 292 2.24E-46 T 29-03-2018 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 Gene3D G3DSA:3.40.190.10 90 179 2.1E-21 T 29-03-2018 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.5E-23 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 SUPERFAMILY SSF46785 5 89 2.12E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 Gene3D G3DSA:1.10.10.10 3 86 9.7E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15890 2cd800a207c884c96d7d0cdcd45213a9 300 Gene3D G3DSA:3.40.190.10 180 266 2.6E-23 T 29-03-2018 CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 Gene3D G3DSA:3.40.50.300 4 345 3.4E-37 T 29-03-2018 CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 SUPERFAMILY SSF52540 734 899 1.06E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 SUPERFAMILY SSF52540 607 674 1.06E-32 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 Gene3D G3DSA:3.40.50.300 623 1139 1.9E-41 T 29-03-2018 CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 SUPERFAMILY SSF52540 32 242 5.23E-31 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 Pfam PF00350 Dynamin family 624 850 9.5E-47 T 29-03-2018 IPR022812 Dynamin superfamily CSW12_RS19735 5ab669e69f51f99f4b4bd1798afdc2c4 1219 Pfam PF00350 Dynamin family 46 200 2.3E-30 T 29-03-2018 IPR022812 Dynamin superfamily CSW12_RS15520 094298de666b292d3ab22765810114be 234 Gene3D G3DSA:3.90.470.20 1 107 1.1E-19 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS15520 094298de666b292d3ab22765810114be 234 SUPERFAMILY SSF56214 7 91 1.52E-23 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS15520 094298de666b292d3ab22765810114be 234 Gene3D G3DSA:3.90.470.20 108 216 1.4E-16 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS15520 094298de666b292d3ab22765810114be 234 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 97 159 6.9E-14 T 29-03-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CSW12_RS15520 094298de666b292d3ab22765810114be 234 SUPERFAMILY SSF56214 98 213 9.03E-26 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS15520 094298de666b292d3ab22765810114be 234 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 99 195 4.1E-17 T 29-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CSW12_RS15325 1280593bc021a8b4ddd66c477a6d3a9a 273 Pfam PF01522 Polysaccharide deacetylase 65 170 2.5E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS15325 1280593bc021a8b4ddd66c477a6d3a9a 273 SUPERFAMILY SSF88713 64 265 5.93E-55 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS15325 1280593bc021a8b4ddd66c477a6d3a9a 273 Gene3D G3DSA:3.20.20.370 1 273 3.8E-47 T 29-03-2018 CSW12_RS21960 0fbfed74bf913cb93688c2adde7889a2 277 Pfam PF01578 Cytochrome C assembly protein 71 270 4.5E-27 T 29-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CSW12_RS25275 1edbd70c3f0df080c12cf73a04357841 250 SMART SM00382 26 213 1.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25275 1edbd70c3f0df080c12cf73a04357841 250 Gene3D G3DSA:3.40.50.300 1 230 1.5E-52 T 29-03-2018 CSW12_RS25275 1edbd70c3f0df080c12cf73a04357841 250 Pfam PF00005 ABC transporter 21 164 3.1E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25275 1edbd70c3f0df080c12cf73a04357841 250 SUPERFAMILY SSF52540 2 226 1.52E-54 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11595 52707aa66c4470a05a7ebbbc87e1e3e2 415 PIRSF PIRSF033563 1 415 1.1E-164 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 CSW12_RS11595 52707aa66c4470a05a7ebbbc87e1e3e2 415 Pfam PF06245 Protein of unknown function (DUF1015) 4 412 1.1E-142 T 29-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 CSW12_RS11595 52707aa66c4470a05a7ebbbc87e1e3e2 415 Gene3D G3DSA:3.90.1530.10 112 300 0.0016 T 29-03-2018 CSW12_RS15495 6756a975cd4e0bf344c0a100ef651ec9 326 TIGRFAM TIGR03814 Gln_ase: glutaminase A 17 326 1.0E-121 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CSW12_RS15495 6756a975cd4e0bf344c0a100ef651ec9 326 Gene3D G3DSA:3.40.710.10 10 326 1.8E-116 T 29-03-2018 CSW12_RS15495 6756a975cd4e0bf344c0a100ef651ec9 326 SUPERFAMILY SSF56601 15 326 5.81E-119 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS15495 6756a975cd4e0bf344c0a100ef651ec9 326 Hamap MF_00313 Glutaminase [glsA]. 13 326 45.059 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CSW12_RS15495 6756a975cd4e0bf344c0a100ef651ec9 326 Pfam PF04960 Glutaminase 31 326 1.1E-107 T 29-03-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 CSW12_RS26685 5641df0c918a48e63170dcb895e3fee9 270 Gene3D G3DSA:3.40.50.300 1 243 1.0E-60 T 29-03-2018 CSW12_RS26685 5641df0c918a48e63170dcb895e3fee9 270 Pfam PF00005 ABC transporter 20 167 1.7E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26685 5641df0c918a48e63170dcb895e3fee9 270 SMART SM00382 28 217 1.2E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26685 5641df0c918a48e63170dcb895e3fee9 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26685 5641df0c918a48e63170dcb895e3fee9 270 SUPERFAMILY SSF52540 4 232 9.61E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 Gene3D G3DSA:1.20.1640.10 798 1029 3.9E-22 T 29-03-2018 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 Gene3D G3DSA:1.20.1640.10 115 341 7.3E-30 T 29-03-2018 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 SUPERFAMILY SSF82866 143 340 5.89E-31 T 29-03-2018 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 SUPERFAMILY SSF82866 848 1029 3.66E-23 T 29-03-2018 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 Gene3D G3DSA:1.20.120.570 602 781 3.6E-21 T 29-03-2018 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 Gene3D G3DSA:1.20.120.570 436 601 1.4E-12 T 29-03-2018 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 Pfam PF03176 MMPL family 45 369 9.7E-59 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CSW12_RS12940 70a4f6d311ed8774645371ab6cc35ece 1041 Pfam PF03176 MMPL family 735 1030 3.1E-39 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CSW12_RS17540 2b74b496279f173f0dbd6d154b458750 405 SUPERFAMILY SSF103473 15 398 3.79E-31 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS17540 2b74b496279f173f0dbd6d154b458750 405 Gene3D G3DSA:1.20.1250.20 3 193 1.8E-10 T 29-03-2018 CSW12_RS17540 2b74b496279f173f0dbd6d154b458750 405 Pfam PF07690 Major Facilitator Superfamily 37 353 3.9E-14 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS17540 2b74b496279f173f0dbd6d154b458750 405 Gene3D G3DSA:1.20.1250.20 200 398 3.8E-18 T 29-03-2018 CSW12_RS09565 e9d26e4cd5cac0de66d3f27bc947422e 267 Pfam PF13672 Protein phosphatase 2C 14 221 2.0E-15 T 29-03-2018 CSW12_RS09565 e9d26e4cd5cac0de66d3f27bc947422e 267 SMART SM00332 1 265 0.0013 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS09565 e9d26e4cd5cac0de66d3f27bc947422e 267 Gene3D G3DSA:3.60.40.10 1 267 1.7E-18 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS09565 e9d26e4cd5cac0de66d3f27bc947422e 267 SUPERFAMILY SSF81606 4 267 4.58E-20 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS26145 be9b1b4d7c7c2761bc0dbcba1f2928f6 255 Gene3D G3DSA:3.20.20.140 1 229 4.4E-27 T 29-03-2018 CSW12_RS26145 be9b1b4d7c7c2761bc0dbcba1f2928f6 255 SUPERFAMILY SSF89550 1 204 2.55E-15 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CSW12_RS26145 be9b1b4d7c7c2761bc0dbcba1f2928f6 255 PIRSF PIRSF016557 1 255 7.3E-114 T 29-03-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 CSW12_RS24800 750532f4afc043fadbb5f8412f636e53 61 Gene3D G3DSA:1.20.1260.10 1 61 2.2E-9 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS02635 55e9212cd51c281bcf4c283c9511fe4a 210 TIGRFAM TIGR01076 sortase_fam: sortase 81 205 4.0E-25 T 29-03-2018 IPR005754 Sortase family CSW12_RS02635 55e9212cd51c281bcf4c283c9511fe4a 210 Pfam PF04203 Sortase family 83 204 5.1E-29 T 29-03-2018 IPR005754 Sortase family CSW12_RS02635 55e9212cd51c281bcf4c283c9511fe4a 210 Gene3D G3DSA:2.40.260.10 50 210 2.1E-42 T 29-03-2018 IPR023365 Sortase domain CSW12_RS02635 55e9212cd51c281bcf4c283c9511fe4a 210 SUPERFAMILY SSF63817 12 206 1.57E-45 T 29-03-2018 IPR023365 Sortase domain CSW12_RS15575 fc03656bddfee9a1c319ca6ae10ad444 92 SMART SM00966 8 51 2.0E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS15575 fc03656bddfee9a1c319ca6ae10ad444 92 SUPERFAMILY SSF89447 1 50 5.62E-14 T 29-03-2018 CSW12_RS15575 fc03656bddfee9a1c319ca6ae10ad444 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 52 1.6E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS15575 fc03656bddfee9a1c319ca6ae10ad444 92 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 48 1.9E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS15575 fc03656bddfee9a1c319ca6ae10ad444 92 Gene3D G3DSA:2.10.260.10 1 48 6.0E-17 T 29-03-2018 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 308 1.8E-36 T 29-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 Gene3D G3DSA:3.40.47.10 161 308 1.0E-43 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 SUPERFAMILY SSF53901 3 308 1.56E-72 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 73.001 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 9.5E-32 T 29-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 Gene3D G3DSA:3.40.47.10 1 160 1.3E-39 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS05405 31f3f0ac382d0836df9c6b11ec61411e 310 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 308 4.8E-134 T 29-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 SMART SM00411 1 90 5.2E-49 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 SUPERFAMILY SSF47729 1 90 8.83E-35 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.0E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.0E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.0E-21 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 29-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.8E-36 T 29-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CSW12_RS16145 61f049d253aa7d8e2ade5a9a76d7ba10 90 Gene3D G3DSA:4.10.520.10 1 90 1.1E-37 T 29-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CSW12_RS31195 960679831c082eee62323734fcae6c3c 116 Pfam PF08863 YolD-like protein 21 111 7.2E-25 T 29-03-2018 IPR014962 YolD-like protein CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 SUPERFAMILY SSF52821 367 473 4.85E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 Gene3D G3DSA:3.60.15.10 1 263 3.1E-33 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 SUPERFAMILY SSF52821 250 354 3.93E-11 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 SMART SM00849 12 199 5.6E-19 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 SMART SM00450 375 470 7.0E-23 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 Pfam PF00581 Rhodanese-like domain 379 466 2.7E-15 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 Pfam PF00581 Rhodanese-like domain 275 337 4.6E-5 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 SUPERFAMILY SSF56281 5 262 1.4E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 Gene3D G3DSA:3.40.250.10 367 477 1.9E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 Gene3D G3DSA:3.40.250.10 264 358 3.6E-9 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS10335 c0a588295589bf15aaf77d8f4b4ce31a 478 Pfam PF00753 Metallo-beta-lactamase superfamily 13 196 6.1E-8 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16465 329479c47f388d57daa08fd616b790b0 71 Pfam PF06855 YozE SAM-like fold 4 69 4.3E-24 T 29-03-2018 IPR023089 YozE SAM-like domain CSW12_RS16465 329479c47f388d57daa08fd616b790b0 71 Hamap MF_01538 UPF0346 protein . 1 70 23.177 T 29-03-2018 IPR010673 Protein of unknown function UPF0346 CSW12_RS16465 329479c47f388d57daa08fd616b790b0 71 PIRSF PIRSF037262 1 71 2.7E-30 T 29-03-2018 IPR010673 Protein of unknown function UPF0346 CSW12_RS16465 329479c47f388d57daa08fd616b790b0 71 Gene3D G3DSA:1.10.150.260 3 70 3.8E-24 T 29-03-2018 IPR023089 YozE SAM-like domain CSW12_RS16465 329479c47f388d57daa08fd616b790b0 71 SUPERFAMILY SSF140652 2 70 2.62E-25 T 29-03-2018 IPR023089 YozE SAM-like domain CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 500 518 5.1E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 446 460 5.1E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 526 541 5.1E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 160 178 5.1E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 463 479 5.1E-32 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 Pfam PF01752 Collagenase 300 633 2.2E-80 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 SUPERFAMILY SSF89260 769 877 1.57E-29 T 29-03-2018 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 Gene3D G3DSA:2.60.120.380 760 878 3.8E-19 T 29-03-2018 CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 Pfam PF08453 Peptidase family M9 N-terminal 94 273 3.5E-55 T 29-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain CSW12_RS12585 92576fb076dfb392c86f7c86bc9f79fe 878 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 799 864 5.8E-6 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial CSW12_RS13065 e7acf27c6dc9347f47a80445651163b0 251 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS13065 e7acf27c6dc9347f47a80445651163b0 251 Pfam PF00005 ABC transporter 22 158 1.2E-33 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS13065 e7acf27c6dc9347f47a80445651163b0 251 SUPERFAMILY SSF52540 3 234 1.77E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13065 e7acf27c6dc9347f47a80445651163b0 251 Gene3D G3DSA:3.40.50.300 1 240 1.1E-60 T 29-03-2018 CSW12_RS13065 e7acf27c6dc9347f47a80445651163b0 251 SMART SM00382 31 208 3.6E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS24895 ff1c5bc0bd7c4d5214383bcc1f8e0c7a 260 PRINTS PR00701 60kDa inner membrane protein signature 214 237 1.2E-13 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS24895 ff1c5bc0bd7c4d5214383bcc1f8e0c7a 260 PRINTS PR00701 60kDa inner membrane protein signature 128 151 1.2E-13 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS24895 ff1c5bc0bd7c4d5214383bcc1f8e0c7a 260 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 251 30.225 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CSW12_RS24895 ff1c5bc0bd7c4d5214383bcc1f8e0c7a 260 Pfam PF02096 60Kd inner membrane protein 61 248 8.5E-55 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS24895 ff1c5bc0bd7c4d5214383bcc1f8e0c7a 260 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 247 1.8E-61 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CSW12_RS16255 71be7cc5214653b589120fa67876f6f1 351 Gene3D G3DSA:3.90.226.10 1 340 1.8E-78 T 29-03-2018 CSW12_RS16255 71be7cc5214653b589120fa67876f6f1 351 Pfam PF16113 Enoyl-CoA hydratase/isomerase 15 346 1.7E-119 T 29-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CSW12_RS16255 71be7cc5214653b589120fa67876f6f1 351 SUPERFAMILY SSF52096 256 332 3.22E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS16255 71be7cc5214653b589120fa67876f6f1 351 SUPERFAMILY SSF52096 3 189 3.22E-59 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS07875 a1a826a08741bcaaaa1f8849db5130ef 48 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 26 47 2.3E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS07875 a1a826a08741bcaaaa1f8849db5130ef 48 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 22 45 2.4E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS25280 a60d97dd4210a45dd228d3d717799578 354 SUPERFAMILY SSF81345 31 350 6.15E-54 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS25280 a60d97dd4210a45dd228d3d717799578 354 Pfam PF01032 FecCD transport family 68 350 4.6E-42 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS25280 a60d97dd4210a45dd228d3d717799578 354 Gene3D G3DSA:1.10.3470.10 30 354 1.1E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 Pfam PF00571 CBS domain 3 56 2.8E-16 T 29-03-2018 IPR000644 CBS domain CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 Pfam PF00571 CBS domain 77 128 4.2E-9 T 29-03-2018 IPR000644 CBS domain CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 Gene3D G3DSA:3.30.70.260 144 203 1.9E-10 T 29-03-2018 CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 SMART SM00116 10 58 2.2E-12 T 29-03-2018 IPR000644 CBS domain CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 SMART SM00116 81 128 3.2E-9 T 29-03-2018 IPR000644 CBS domain CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 Gene3D G3DSA:3.10.580.10 1 143 6.9E-31 T 29-03-2018 CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 Pfam PF01842 ACT domain 139 199 2.5E-10 T 29-03-2018 IPR002912 ACT domain CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 SUPERFAMILY SSF54631 1 130 4.42E-31 T 29-03-2018 CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 140 205 0.007 T 29-03-2018 CSW12_RS22980 9a6b70b1b0462b56dd149202762184d3 214 SUPERFAMILY SSF55021 137 205 1.12E-10 T 29-03-2018 CSW12_RS13715 296ad21f7a8c19cb8297b76536772e4c 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 2.2E-12 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CSW12_RS13715 296ad21f7a8c19cb8297b76536772e4c 106 SUPERFAMILY SSF54292 11 90 3.82E-19 T 29-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CSW12_RS13715 296ad21f7a8c19cb8297b76536772e4c 106 Gene3D G3DSA:3.10.20.30 3 99 1.1E-18 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS15650 dff2be6c579121141d1e34d7f0517890 245 ProDom PD120066 SPORULATION STAGE SA II SPOIISA TRANSMEMBRANE MEMBRANE KILLER 24 156 0.001 T 29-03-2018 CSW12_RS15650 dff2be6c579121141d1e34d7f0517890 245 Pfam PF14171 Toxin SpoIISA, type II toxin-antitoxin system 10 243 2.2E-69 T 29-03-2018 IPR025940 Toxin SpoIISA, type II toxin-antitoxin system GO:0009405|GO:0016021 CSW12_RS26675 3e55a89641dd41087feb33e5a7ab2dbb 434 SUPERFAMILY SSF109604 3 413 1.91E-120 T 29-03-2018 CSW12_RS26675 3e55a89641dd41087feb33e5a7ab2dbb 434 SMART SM00471 57 187 3.7E-12 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS26675 3e55a89641dd41087feb33e5a7ab2dbb 434 Pfam PF01966 HD domain 61 180 4.4E-17 T 29-03-2018 IPR006674 HD domain CSW12_RS26675 3e55a89641dd41087feb33e5a7ab2dbb 434 Gene3D G3DSA:1.10.3210.10 10 312 6.5E-79 T 29-03-2018 CSW12_RS00900 812e9e5833ce28e859f3c0aa7d62a19d 196 Pfam PF02342 TerD domain 5 191 1.3E-82 T 29-03-2018 IPR003325 TerD domain GO:0006950 CSW12_RS00900 812e9e5833ce28e859f3c0aa7d62a19d 196 Gene3D G3DSA:2.60.60.30 22 190 2.0E-63 T 29-03-2018 CSW12_RS03200 c4492f94e55fa8820d87dfead09f0ad6 194 Pfam PF11579 Protein of unknown function (DUF3238) 1 193 1.0E-117 T 29-03-2018 IPR021631 Protein of unknown function DUF3238 CSW12_RS28865 9e1fa8a02ed3da00912b99139509ffc0 441 PIRSF PIRSF005353 1 441 1.4E-171 T 29-03-2018 IPR026033 Purine permease PbuG-like CSW12_RS28865 9e1fa8a02ed3da00912b99139509ffc0 441 Pfam PF00860 Permease family 17 402 2.7E-41 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS04365 a3657f3a848338d68c097ecafd4cc923 328 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 2 316 1.1E-113 T 29-03-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal CSW12_RS04365 a3657f3a848338d68c097ecafd4cc923 328 Gene3D G3DSA:3.60.60.10 2 327 1.1E-88 T 29-03-2018 CSW12_RS04365 a3657f3a848338d68c097ecafd4cc923 328 SUPERFAMILY SSF56235 2 328 1.0E-117 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 SUPERFAMILY SSF51735 3 167 8.95E-61 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 9.0E-69 T 29-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 29-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 8.9E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 8.9E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 8.9E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 8.9E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 8.9E-42 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 SMART SM00846 2 151 8.6E-86 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 7.8E-135 T 29-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 PIRSF PIRSF000149 1 334 1.3E-137 T 29-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 SUPERFAMILY SSF55347 151 313 5.95E-73 T 29-03-2018 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 101 4.7E-38 T 29-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 Gene3D G3DSA:3.40.50.720 1 160 6.5E-74 T 29-03-2018 CSW12_RS22535 868077dd60fd27a975acbdb3904887ff 342 Gene3D G3DSA:3.30.360.10 161 314 3.5E-68 T 29-03-2018 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 355 375 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 PRINTS PR00173 Glutamate-aspartate symporter signature 219 238 1.5E-37 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 SUPERFAMILY SSF118215 6 402 1.31E-125 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 29-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 Gene3D G3DSA:1.10.3860.10 1 408 8.4E-129 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS18820 49999b1209e7095713ac4781917d61d3 423 Pfam PF00375 Sodium:dicarboxylate symporter family 6 401 9.8E-126 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 Gene3D G3DSA:3.40.50.2300 58 163 1.8E-22 T 29-03-2018 CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.2E-18 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 60 310 2.1E-26 T 29-03-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 Gene3D G3DSA:1.10.260.40 2 57 9.8E-20 T 29-03-2018 CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 SMART SM00354 1 71 3.2E-28 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 Gene3D G3DSA:3.40.50.2300 164 325 8.9E-35 T 29-03-2018 CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 SUPERFAMILY SSF53822 61 325 1.16E-54 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS26795 4d7d72d21c8fec0f48e9c824410e670e 325 SUPERFAMILY SSF47413 1 60 3.02E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 ProSitePatterns PS00455 Putative AMP-binding domain signature. 176 187 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 512 1.7E-23 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 SUPERFAMILY SSF56801 24 524 1.03E-137 T 29-03-2018 CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 Gene3D G3DSA:3.30.300.30 418 528 5.2E-30 T 29-03-2018 CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 Gene3D G3DSA:3.40.50.980 182 331 1.3E-36 T 29-03-2018 CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 Gene3D G3DSA:2.30.38.10 332 417 9.8E-21 T 29-03-2018 CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 Pfam PF00501 AMP-binding enzyme 25 424 2.9E-79 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS22870 b0fca98763f06a6da16acc10f900eb15 528 Gene3D G3DSA:3.40.50.980 16 181 2.2E-32 T 29-03-2018 CSW12_RS07105 6b4113f1a8a244624b255953ed534a4e 70 Pfam PF14140 YpzI-like protein 27 68 2.1E-25 T 29-03-2018 IPR025414 YpzI-like protein CSW12_RS26045 7708db518463b9f462569d27ec40ae6b 63 SMART SM00530 3 58 1.6E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS26045 7708db518463b9f462569d27ec40ae6b 63 SUPERFAMILY SSF47413 2 61 4.02E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS26045 7708db518463b9f462569d27ec40ae6b 63 Pfam PF01381 Helix-turn-helix 4 56 8.9E-17 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS26045 7708db518463b9f462569d27ec40ae6b 63 Gene3D G3DSA:1.10.260.40 1 62 9.3E-17 T 29-03-2018 CSW12_RS12520 aeadb8f0bc11165f0466350a496a5143 214 SUPERFAMILY SSF53474 10 192 6.23E-6 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12520 aeadb8f0bc11165f0466350a496a5143 214 PIRSF PIRSF033634 1 214 5.0E-74 T 29-03-2018 IPR017018 Uncharacterised conserved protein UCP033634 CSW12_RS07725 a708433744435543de33687223597245 185 SUPERFAMILY SSF46785 3 171 1.43E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07725 a708433744435543de33687223597245 185 Gene3D G3DSA:1.10.10.10 1 94 2.5E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07725 a708433744435543de33687223597245 185 Pfam PF03551 Transcriptional regulator PadR-like family 7 81 2.8E-9 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS00625 cdb880f6a5a170e4d4571c8e3d802f56 222 ProDom PD210561 YWRJ 1 222 5.0E-125 T 29-03-2018 IPR020173 Uncharacterised protein family YwrJ CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 Gene3D G3DSA:3.90.1150.10 1 159 9.1E-46 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 Gene3D G3DSA:3.40.640.10 160 274 1.9E-40 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 PIRSF PIRSF000521 154 381 3.4E-42 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 PIRSF PIRSF000521 108 150 0.023 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 PIRSF PIRSF000521 4 115 5.4E-7 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 Pfam PF00202 Aminotransferase class-III 14 378 8.3E-124 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 378 1.5E-153 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 SUPERFAMILY SSF53383 4 378 8.34E-126 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 2 379 46.311 T 29-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 205 242 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS20195 47ea0585b8190155d8ca871dafa62151 386 Gene3D G3DSA:3.90.1150.10 275 382 5.1E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS23405 8adcfa95ee7102d8318b97d6cbe28604 188 SUPERFAMILY SSF56349 9 178 6.18E-28 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS23405 8adcfa95ee7102d8318b97d6cbe28604 188 Gene3D G3DSA:1.10.443.10 5 178 6.2E-26 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS23405 8adcfa95ee7102d8318b97d6cbe28604 188 Pfam PF00589 Phage integrase family 11 172 1.1E-15 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS20125 febae4d1e936dbed789069535de4cd73 269 Gene3D G3DSA:3.40.50.150 2 240 2.5E-36 T 29-03-2018 CSW12_RS20125 febae4d1e936dbed789069535de4cd73 269 SUPERFAMILY SSF53335 10 188 3.19E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS20125 febae4d1e936dbed789069535de4cd73 269 Pfam PF13847 Methyltransferase domain 44 170 5.3E-24 T 29-03-2018 IPR025714 Methyltransferase domain CSW12_RS20125 febae4d1e936dbed789069535de4cd73 269 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 2 265 30.14 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 CSW12_RS20125 febae4d1e936dbed789069535de4cd73 269 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 10 265 1.1E-81 T 29-03-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 Pfam PF13354 Beta-lactamase enzyme family 79 284 2.1E-32 T 29-03-2018 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 Gene3D G3DSA:3.40.710.10 55 312 2.7E-29 T 29-03-2018 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 ProSitePatterns PS00146 Beta-lactamase class-A active site. 91 106 - T 29-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 58 82 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 191 216 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 227 242 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 129 154 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 165 189 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 89 106 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 PRINTS PR00118 Beta-lactamase class A signature 244 259 3.3E-68 T 29-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CSW12_RS15085 6ce3ebff92e190acae183959b08f4315 312 SUPERFAMILY SSF56601 57 308 2.64E-73 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS16055 690a828aba6c3fd1d9804e31b73af39c 290 Pfam PF00753 Metallo-beta-lactamase superfamily 30 225 1.3E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16055 690a828aba6c3fd1d9804e31b73af39c 290 SUPERFAMILY SSF56281 25 244 4.19E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16055 690a828aba6c3fd1d9804e31b73af39c 290 SMART SM00849 25 225 2.2E-16 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16055 690a828aba6c3fd1d9804e31b73af39c 290 Gene3D G3DSA:3.60.15.10 4 249 1.0E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07340 4070a856fb2ecd5c32e2600eaaf12dbf 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 333 1.3E-161 T 29-03-2018 IPR010894 Stage V sporulation AD CSW12_RS07340 4070a856fb2ecd5c32e2600eaaf12dbf 338 SUPERFAMILY SSF53901 57 310 3.46E-15 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS07340 4070a856fb2ecd5c32e2600eaaf12dbf 338 Gene3D G3DSA:3.40.50.2000 168 249 0.15 T 29-03-2018 CSW12_RS07340 4070a856fb2ecd5c32e2600eaaf12dbf 338 Gene3D G3DSA:3.40.47.10 12 167 4.6E-6 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS07340 4070a856fb2ecd5c32e2600eaaf12dbf 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 333 1.1E-155 T 29-03-2018 IPR010894 Stage V sporulation AD CSW12_RS07340 4070a856fb2ecd5c32e2600eaaf12dbf 338 PIRSF PIRSF011570 1 336 2.3E-164 T 29-03-2018 IPR010894 Stage V sporulation AD CSW12_RS21670 d8dd99ce9a35b51170c2b173429b66db 146 SUPERFAMILY SSF69500 1 144 6.02E-60 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CSW12_RS21670 d8dd99ce9a35b51170c2b173429b66db 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.325 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CSW12_RS21670 d8dd99ce9a35b51170c2b173429b66db 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 2.0E-58 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CSW12_RS21670 d8dd99ce9a35b51170c2b173429b66db 146 Gene3D G3DSA:3.50.80.10 1 145 3.6E-60 T 29-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CSW12_RS21670 d8dd99ce9a35b51170c2b173429b66db 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.5E-60 T 29-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CSW12_RS30745 12b0de0440c3c1cf056e99b34d2f8e16 74 SUPERFAMILY SSF47413 10 60 9.85E-6 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS30745 12b0de0440c3c1cf056e99b34d2f8e16 74 Gene3D G3DSA:1.10.260.40 4 72 4.2E-6 T 29-03-2018 CSW12_RS19180 df1aaa257300da46ff9afc8533394dfa 56 Pfam PF13131 Protein of unknown function (DUF3951) 1 52 5.5E-28 T 29-03-2018 IPR025028 Protein of unknown function DUF3951 CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 122 1.4E-30 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 Gene3D G3DSA:3.90.230.10 171 418 3.4E-70 T 29-03-2018 CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 Pfam PF00557 Metallopeptidase family M24 179 391 5.2E-54 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 SUPERFAMILY SSF53092 2 172 3.14E-37 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 SMART SM01011 1 137 7.7E-37 T 29-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 Gene3D G3DSA:3.40.350.10 1 170 3.9E-41 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CSW12_RS18340 0b7ade0fbbf47f0f058de776715bbcc8 427 SUPERFAMILY SSF55920 173 417 1.7E-65 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 Gene3D G3DSA:3.40.50.2300 1 123 1.7E-34 T 29-03-2018 CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 SUPERFAMILY SSF52172 1 179 9.08E-39 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 SMART SM00862 148 219 7.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-25 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 219 2.4E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 Gene3D G3DSA:1.10.10.10 124 221 2.0E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24960 9e0d1724d0673209f82c35df42d3a342 221 SMART SM00448 2 112 5.6E-38 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23105 0ec58054dd375ef699596dbb064ee4d0 301 SUPERFAMILY SSF103481 38 141 9.15E-17 T 29-03-2018 CSW12_RS23105 0ec58054dd375ef699596dbb064ee4d0 301 Pfam PF00892 EamA-like transporter family 153 287 2.0E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS23105 0ec58054dd375ef699596dbb064ee4d0 301 Pfam PF00892 EamA-like transporter family 9 139 2.0E-25 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS23105 0ec58054dd375ef699596dbb064ee4d0 301 SUPERFAMILY SSF103481 189 286 1.24E-7 T 29-03-2018 CSW12_RS17640 ca212debe518daf83d06746460811fc8 152 Gene3D G3DSA:1.20.1260.10 1 140 7.3E-12 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS17640 ca212debe518daf83d06746460811fc8 152 Pfam PF07875 Coat F domain 83 140 3.2E-8 T 29-03-2018 IPR012851 Spore coat protein CotF-like CSW12_RS04390 61325f78513a1179416af585c6ce0127 974 Gene3D G3DSA:1.20.5.50 256 358 1.8E-4 T 29-03-2018 CSW12_RS04390 61325f78513a1179416af585c6ce0127 974 Gene3D G3DSA:3.40.50.300 1 255 1.1E-12 T 29-03-2018 CSW12_RS04390 61325f78513a1179416af585c6ce0127 974 Gene3D G3DSA:3.40.50.300 606 971 3.9E-10 T 29-03-2018 CSW12_RS04390 61325f78513a1179416af585c6ce0127 974 Pfam PF13514 AAA domain 1 198 3.4E-27 T 29-03-2018 CSW12_RS04390 61325f78513a1179416af585c6ce0127 974 SUPERFAMILY SSF52540 863 963 2.95E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04390 61325f78513a1179416af585c6ce0127 974 SUPERFAMILY SSF52540 1 216 2.95E-17 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Gene3D G3DSA:3.20.20.80 1 117 9.1E-46 T 29-03-2018 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Gene3D G3DSA:2.60.40.1180 466 553 2.0E-22 T 29-03-2018 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 SUPERFAMILY SSF51011 472 550 1.39E-18 T 29-03-2018 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Pfam PF16657 Maltogenic Amylase, C-terminal domain 472 545 6.1E-8 T 29-03-2018 IPR032091 Maltogenic Amylase, C-terminal CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Pfam PF00128 Alpha amylase, catalytic domain 26 369 3.2E-124 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Gene3D G3DSA:3.90.400.10 118 162 3.5E-24 T 29-03-2018 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 4 550 5.4E-276 T 29-03-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 SMART SM00642 11 411 1.6E-150 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Gene3D G3DSA:3.20.20.80 339 465 4.0E-23 T 29-03-2018 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 Gene3D G3DSA:3.20.20.470 163 338 3.2E-38 T 29-03-2018 CSW12_RS01865 2334dbee9ef5f15b0ab486f73e976aae 553 SUPERFAMILY SSF51445 3 469 6.18E-152 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS21525 8db5d02ba1fafdf31753e3e195e44531 584 Pfam PF00905 Penicillin binding protein transpeptidase domain 263 573 2.4E-48 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS21525 8db5d02ba1fafdf31753e3e195e44531 584 SUPERFAMILY SSF56601 188 396 1.49E-57 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS21525 8db5d02ba1fafdf31753e3e195e44531 584 SUPERFAMILY SSF56601 430 581 1.49E-57 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS21525 8db5d02ba1fafdf31753e3e195e44531 584 Gene3D G3DSA:3.90.1310.10 19 235 2.8E-12 T 29-03-2018 CSW12_RS21525 8db5d02ba1fafdf31753e3e195e44531 584 SUPERFAMILY SSF56519 50 234 1.83E-17 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS21525 8db5d02ba1fafdf31753e3e195e44531 584 Gene3D G3DSA:3.40.710.10 238 584 1.7E-63 T 29-03-2018 CSW12_RS14660 ae3ddfdef9613e37135940cd8db59824 97 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 3 82 6.7E-36 T 29-03-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family CSW12_RS12480 7a014c1fc5f6afcca0cc6aaabce1a8d5 156 PIRSF PIRSF037663 1 156 2.7E-75 T 29-03-2018 IPR017255 Acetyltransferase, GNAT, predicted CSW12_RS12480 7a014c1fc5f6afcca0cc6aaabce1a8d5 156 Pfam PF00583 Acetyltransferase (GNAT) family 24 124 5.2E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS12480 7a014c1fc5f6afcca0cc6aaabce1a8d5 156 SUPERFAMILY SSF55729 1 154 2.98E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12480 7a014c1fc5f6afcca0cc6aaabce1a8d5 156 Gene3D G3DSA:3.40.630.30 1 156 1.1E-24 T 29-03-2018 CSW12_RS02165 e80354e11265bed9ed936181cd51d1e6 395 Pfam PF04860 Phage portal protein 46 356 1.1E-38 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CSW12_RS02165 e80354e11265bed9ed936181cd51d1e6 395 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 40 362 3.7E-53 T 29-03-2018 IPR006427 Phage portal protein, HK97 CSW12_RS14705 e01eef5fee3009531b09c8e6f2f2e191 228 Pfam PF17294 Uncharacterised lipoprotein family 35 203 2.1E-45 T 29-03-2018 IPR035253 Putative lipoprotein, bacteria CSW12_RS28050 0a8b9c4db87204f6ab3c67991aa791df 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 29-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28050 0a8b9c4db87204f6ab3c67991aa791df 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.4E-25 T 29-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28050 0a8b9c4db87204f6ab3c67991aa791df 61 Gene3D G3DSA:4.10.830.10 1 61 2.1E-21 T 29-03-2018 CSW12_RS28050 0a8b9c4db87204f6ab3c67991aa791df 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.091 T 29-03-2018 IPR023053 Ribosomal protein S14, type Z CSW12_RS28050 0a8b9c4db87204f6ab3c67991aa791df 61 SUPERFAMILY SSF57716 3 61 5.42E-22 T 29-03-2018 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 Pfam PF00005 ABC transporter 355 500 1.0E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 SUPERFAMILY SSF52540 330 570 4.49E-71 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 SUPERFAMILY SSF90123 5 315 2.09E-43 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 Gene3D G3DSA:3.40.50.300 322 573 1.7E-70 T 29-03-2018 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 3 531 4.6E-202 T 29-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 Pfam PF00664 ABC transporter transmembrane region 26 280 9.4E-12 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 SMART SM00382 364 547 2.2E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS18140 f4ccb722b2d0e511e771580d2eda0842 574 Gene3D G3DSA:1.20.1560.10 3 312 1.9E-28 T 29-03-2018 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 SUPERFAMILY SSF54966 2 121 4.0E-30 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 127 403 1.3E-34 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 Gene3D G3DSA:3.20.20.110 122 414 2.5E-80 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 3 101 3.8E-5 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 Gene3D G3DSA:3.30.70.150 2 121 1.6E-28 T 29-03-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 SUPERFAMILY SSF51649 121 411 2.22E-79 T 29-03-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 406 1.9E-237 T 29-03-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 CSW12_RS07505 341654fd4072dfdfef3c54b9d39e5718 414 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 406 62.479 T 29-03-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 CSW12_RS03075 a66eadc2b024cfb034739c5aa582fecf 253 Pfam PF03734 L,D-transpeptidase catalytic domain 24 142 9.4E-24 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CSW12_RS03075 a66eadc2b024cfb034739c5aa582fecf 253 Gene3D G3DSA:2.40.440.10 17 144 8.7E-35 T 29-03-2018 CSW12_RS03075 a66eadc2b024cfb034739c5aa582fecf 253 SUPERFAMILY SSF141523 23 142 2.35E-34 T 29-03-2018 CSW12_RS22110 92f1ee66f249fe2d2c410e15018448ec 61 Pfam PF04024 PspC domain 3 59 1.5E-19 T 29-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 PIRSF PIRSF004793 1 201 1.7E-64 T 29-03-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 Gene3D G3DSA:3.40.1700.10 71 199 2.0E-35 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 Gene3D G3DSA:1.10.287.770 8 69 5.7E-24 T 29-03-2018 CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 78 194 7.0E-41 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 SUPERFAMILY SSF143597 32 198 4.05E-53 T 29-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 Hamap MF_00838 Diadenylate cyclase [dacB]. 14 201 36.797 T 29-03-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 CSW12_RS24390 6644b97dad66b000d5ede56b53ef50fe 201 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 1 69 2.4E-26 T 29-03-2018 IPR019457 Uncharacterised domain YojJ, N-terminal CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 Pfam PF02609 Exonuclease VII small subunit 7 57 3.2E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 47 9.0E-20 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 SUPERFAMILY SSF116842 3 66 3.4E-21 T 29-03-2018 CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 Gene3D G3DSA:1.10.287.1040 4 69 3.8E-24 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 15.072 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 PIRSF PIRSF006488 1 76 1.1E-19 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS20480 ef2c8d90885b437630c6543b6af4ceef 76 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 4.6E-22 T 29-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CSW12_RS02665 f2612e73431816c87ee1fc8e2e32f2db 463 PIRSF PIRSF006060 1 461 1.9E-74 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS02665 f2612e73431816c87ee1fc8e2e32f2db 463 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS02665 f2612e73431816c87ee1fc8e2e32f2db 463 Pfam PF00324 Amino acid permease 18 448 1.3E-119 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS23425 43df7e6f3e96a2727ae5173d1214e3b8 340 Pfam PF07786 Protein of unknown function (DUF1624) 9 159 3.4E-6 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 CSW12_RS23425 43df7e6f3e96a2727ae5173d1214e3b8 340 Pfam PF04235 Protein of unknown function (DUF418) 165 333 1.5E-29 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CSW12_RS09990 aac52fadc56dac8f7531ed96e437c748 494 Gene3D G3DSA:3.40.309.10 282 475 3.1E-74 T 29-03-2018 CSW12_RS09990 aac52fadc56dac8f7531ed96e437c748 494 Pfam PF00171 Aldehyde dehydrogenase family 29 489 9.9E-192 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS09990 aac52fadc56dac8f7531ed96e437c748 494 Gene3D G3DSA:3.40.605.10 6 281 3.2E-114 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS09990 aac52fadc56dac8f7531ed96e437c748 494 SUPERFAMILY SSF53720 15 492 6.68E-183 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS09990 aac52fadc56dac8f7531ed96e437c748 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS13550 d380ba18ebc85968c8b465a1bfb34985 221 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 35 198 3.2E-39 T 29-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CSW12_RS13550 d380ba18ebc85968c8b465a1bfb34985 221 SUPERFAMILY SSF81296 35 200 7.0E-63 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS13550 d380ba18ebc85968c8b465a1bfb34985 221 Gene3D G3DSA:2.70.50.50 35 200 1.0E-53 T 29-03-2018 CSW12_RS05880 ab302f9ee5e36ef30c98d060913df836 200 Pfam PF12870 Domain of unknown function (DUF4878) 28 109 5.5E-6 T 29-03-2018 IPR024267 Domain of unknown function (DUF4878) CSW12_RS05880 ab302f9ee5e36ef30c98d060913df836 200 Gene3D G3DSA:3.40.190.10 1 193 6.8E-5 T 29-03-2018 CSW12_RS18555 ea6b0e8069ed61a4115f1e80f526bad2 214 Pfam PF04397 LytTr DNA-binding domain 117 212 9.7E-28 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS18555 ea6b0e8069ed61a4115f1e80f526bad2 214 PIRSF PIRSF036613 1 214 2.0E-142 T 29-03-2018 IPR012072 LytTR signal transduction protein, putative CSW12_RS18555 ea6b0e8069ed61a4115f1e80f526bad2 214 Gene3D G3DSA:2.40.50.40 106 176 4.8E-18 T 29-03-2018 CSW12_RS18555 ea6b0e8069ed61a4115f1e80f526bad2 214 Gene3D G3DSA:2.20.25.10 177 213 1.5E-14 T 29-03-2018 CSW12_RS18555 ea6b0e8069ed61a4115f1e80f526bad2 214 SMART SM00850 116 213 5.8E-30 T 29-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CSW12_RS26080 2cbf89796283d14f7b552bbb8804b24a 330 SUPERFAMILY SSF51735 1 328 7.23E-97 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26080 2cbf89796283d14f7b552bbb8804b24a 330 Gene3D G3DSA:3.90.25.10 166 330 1.3E-40 T 29-03-2018 CSW12_RS26080 2cbf89796283d14f7b552bbb8804b24a 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 327 3.7E-131 T 29-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CSW12_RS26080 2cbf89796283d14f7b552bbb8804b24a 330 Gene3D G3DSA:3.40.50.720 2 165 5.0E-34 T 29-03-2018 CSW12_RS26080 2cbf89796283d14f7b552bbb8804b24a 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 253 2.1E-57 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS21180 9063c4ff76b60592fd029781a7da716f 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 310 2.6E-106 T 29-03-2018 CSW12_RS21180 9063c4ff76b60592fd029781a7da716f 312 PIRSF PIRSF000401 1 312 2.9E-120 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CSW12_RS21180 9063c4ff76b60592fd029781a7da716f 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 37.259 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CSW12_RS21180 9063c4ff76b60592fd029781a7da716f 312 SUPERFAMILY SSF53335 66 309 8.81E-47 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS21180 9063c4ff76b60592fd029781a7da716f 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 3.0E-96 T 29-03-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CSW12_RS21180 9063c4ff76b60592fd029781a7da716f 312 Gene3D G3DSA:3.40.50.150 116 312 8.2E-45 T 29-03-2018 CSW12_RS17080 8dbe91761b3e63d2da2be46d21cbab97 292 SUPERFAMILY SSF53335 4 163 7.54E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS17080 8dbe91761b3e63d2da2be46d21cbab97 292 Pfam PF13847 Methyltransferase domain 38 157 3.6E-22 T 29-03-2018 IPR025714 Methyltransferase domain CSW12_RS17080 8dbe91761b3e63d2da2be46d21cbab97 292 Gene3D G3DSA:3.40.50.150 17 225 5.8E-25 T 29-03-2018 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 SUPERFAMILY SSF51905 4 208 8.37E-27 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 SUPERFAMILY SSF51905 152 333 1.14E-21 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 323 1.7E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 Gene3D G3DSA:3.50.50.60 130 332 3.3E-29 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 Gene3D G3DSA:3.50.50.60 3 129 1.3E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 5.8E-6 T 29-03-2018 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 5.8E-6 T 29-03-2018 CSW12_RS24415 01a0506ec31e811ea77eac3e19830112 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 5.8E-6 T 29-03-2018 CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 PIRSF PIRSF006728 1 412 8.9E-166 T 29-03-2018 IPR008135 Competence-induced protein CinA CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 412 166.644 T 29-03-2018 IPR008135 Competence-induced protein CinA CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 SUPERFAMILY SSF53218 1 205 3.01E-40 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 Gene3D G3DSA:3.40.980.10 1 171 8.3E-43 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 264 409 1.2E-43 T 29-03-2018 IPR008136 CinA, C-terminal CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 SMART SM00852 4 170 3.5E-41 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 Gene3D G3DSA:3.90.950.20 247 412 4.7E-51 T 29-03-2018 CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 Pfam PF02464 Competence-damaged protein 258 408 4.9E-50 T 29-03-2018 IPR008136 CinA, C-terminal CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 410 3.8E-155 T 29-03-2018 IPR008135 Competence-induced protein CinA CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 Pfam PF00994 Probable molybdopterin binding domain 4 169 5.8E-37 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 165 5.5E-33 T 29-03-2018 IPR001453 MoaB/Mog domain CSW12_RS08875 47565a20e29df34a6683b2c0986dfd3e 412 SUPERFAMILY SSF142433 249 410 1.03E-45 T 29-03-2018 IPR008136 CinA, C-terminal CSW12_RS05890 7927c20750b127858ec73e6fa15b69bc 299 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 1.1E-17 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CSW12_RS05890 7927c20750b127858ec73e6fa15b69bc 299 SMART SM00382 27 241 2.4E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05890 7927c20750b127858ec73e6fa15b69bc 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS05890 7927c20750b127858ec73e6fa15b69bc 299 SUPERFAMILY SSF52540 3 223 1.94E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS05890 7927c20750b127858ec73e6fa15b69bc 299 Gene3D G3DSA:3.40.50.300 2 264 2.8E-63 T 29-03-2018 CSW12_RS05890 7927c20750b127858ec73e6fa15b69bc 299 Pfam PF00005 ABC transporter 19 158 6.2E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25725 ba0e4e2323e1ec4f4176ff38f56be2b3 371 Gene3D G3DSA:3.40.50.2000 207 352 1.7E-37 T 29-03-2018 CSW12_RS25725 ba0e4e2323e1ec4f4176ff38f56be2b3 371 Gene3D G3DSA:3.40.50.2000 5 206 1.7E-77 T 29-03-2018 CSW12_RS25725 ba0e4e2323e1ec4f4176ff38f56be2b3 371 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 368 1.2E-165 T 29-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CSW12_RS25725 ba0e4e2323e1ec4f4176ff38f56be2b3 371 SUPERFAMILY SSF53756 4 369 2.28E-139 T 29-03-2018 CSW12_RS25725 ba0e4e2323e1ec4f4176ff38f56be2b3 371 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 365 3.5E-121 T 29-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CSW12_RS02660 7040a6457fbb90ce9d11ad0f6f27ba31 515 SUPERFAMILY SSF52317 203 240 3.66E-10 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS02660 7040a6457fbb90ce9d11ad0f6f27ba31 515 SUPERFAMILY SSF52317 40 166 3.66E-10 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS02660 7040a6457fbb90ce9d11ad0f6f27ba31 515 SUPERFAMILY SSF52317 274 294 3.66E-10 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS02660 7040a6457fbb90ce9d11ad0f6f27ba31 515 Gene3D G3DSA:3.40.50.880 41 346 2.1E-37 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS03025 0dd8e3be30ae0a2b65b946028f5d45fa 555 Pfam PF03814 Potassium-transporting ATPase A subunit 8 552 5.2E-228 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CSW12_RS03025 0dd8e3be30ae0a2b65b946028f5d45fa 555 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 1 554 32.47 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CSW12_RS03025 0dd8e3be30ae0a2b65b946028f5d45fa 555 PIRSF PIRSF001294 1 555 1.0E-233 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CSW12_RS03025 0dd8e3be30ae0a2b65b946028f5d45fa 555 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 3 554 5.0E-202 T 29-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CSW12_RS28610 7ea451ee04d817a674589a20ae43c09e 35 Pfam PF13134 Protein of unknown function (DUF3948) 1 34 8.5E-23 T 29-03-2018 IPR025034 Protein of unknown function DUF3948 CSW12_RS21365 68d6ada1c15878ac28773c70d168c653 277 Gene3D G3DSA:3.40.630.30 1 135 2.8E-15 T 29-03-2018 CSW12_RS21365 68d6ada1c15878ac28773c70d168c653 277 SUPERFAMILY SSF55729 1 256 3.42E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS21365 68d6ada1c15878ac28773c70d168c653 277 Pfam PF13673 Acetyltransferase (GNAT) domain 42 122 4.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS15765 c6f5dd7ee413f3a9013739b0f0f006d9 277 Pfam PF13120 Domain of unknown function (DUF3974) 1 126 2.4E-86 T 29-03-2018 IPR025005 Domain of unknown function DUF3974 CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 SUPERFAMILY SSF51735 8 228 1.68E-72 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 Gene3D G3DSA:3.40.50.720 169 235 1.7E-9 T 29-03-2018 CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 Gene3D G3DSA:3.40.50.720 7 168 1.1E-53 T 29-03-2018 CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.4E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.4E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.4E-15 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.3E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.3E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.3E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.3E-33 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 PIRSF PIRSF000126 4 241 8.4E-64 T 29-03-2018 CSW12_RS18055 1bbce933c1ee9393685515675152b089 242 Pfam PF00106 short chain dehydrogenase 11 199 2.0E-66 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS01265 3297753ab2583c4b9b945e95a7bda128 263 Pfam PF06182 ABC-2 family transporter protein 31 258 2.0E-22 T 29-03-2018 IPR010390 Protein of unknown function DUF990 CSW12_RS13235 a75e351cbd17b204c03d239a4ec43375 321 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 6 308 5.3E-60 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS13235 a75e351cbd17b204c03d239a4ec43375 321 Gene3D G3DSA:3.90.245.10 2 318 6.2E-67 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS13235 a75e351cbd17b204c03d239a4ec43375 321 SUPERFAMILY SSF53590 6 315 8.11E-77 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 212 395 1.4E-48 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 SMART SM00646 277 395 4.5E-41 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 Gene3D G3DSA:3.40.630.40 191 405 2.0E-58 T 29-03-2018 CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 Pfam PF00395 S-layer homology domain 87 129 1.4E-12 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 Pfam PF00395 S-layer homology domain 149 190 5.7E-8 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 Pfam PF00395 S-layer homology domain 32 68 1.1E-6 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS10165 2294dc78260cbd7cd4eb7b93b8efca1b 410 SUPERFAMILY SSF53187 210 401 7.85E-52 T 29-03-2018 CSW12_RS04530 9a0f1b50df53eabe94a48efbe8c5f35f 120 Pfam PF12732 YtxH-like protein 9 83 1.8E-10 T 29-03-2018 IPR024623 Uncharacterised protein family YtxH CSW12_RS04530 9a0f1b50df53eabe94a48efbe8c5f35f 120 Gene3D G3DSA:1.20.120.20 1 120 2.6E-6 T 29-03-2018 CSW12_RS26435 34452d23655a00813c65988d30454050 358 SUPERFAMILY SSF75620 11 354 2.62E-133 T 29-03-2018 CSW12_RS26435 34452d23655a00813c65988d30454050 358 Pfam PF03462 PCRF domain 12 205 1.1E-73 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CSW12_RS26435 34452d23655a00813c65988d30454050 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 4 358 40.835 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CSW12_RS26435 34452d23655a00813c65988d30454050 358 SMART SM00937 66 180 3.8E-65 T 29-03-2018 IPR005139 Peptide chain release factor GO:0006415 CSW12_RS26435 34452d23655a00813c65988d30454050 358 Pfam PF00472 RF-1 domain 213 322 2.9E-40 T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CSW12_RS26435 34452d23655a00813c65988d30454050 358 Gene3D G3DSA:3.30.160.20 210 297 3.4E-30 T 29-03-2018 CSW12_RS26435 34452d23655a00813c65988d30454050 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 29-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CSW12_RS26435 34452d23655a00813c65988d30454050 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 356 3.6E-171 T 29-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CSW12_RS26435 34452d23655a00813c65988d30454050 358 Gene3D G3DSA:1.20.58.410 1 103 6.0E-18 T 29-03-2018 CSW12_RS03705 640b295cd0c1e1532e4a5e7af672b4c2 290 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 268 1.3E-47 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS03705 640b295cd0c1e1532e4a5e7af672b4c2 290 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 241 2.2E-17 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS03705 640b295cd0c1e1532e4a5e7af672b4c2 290 Gene3D G3DSA:3.30.1240.10 83 195 8.3E-45 T 29-03-2018 CSW12_RS03705 640b295cd0c1e1532e4a5e7af672b4c2 290 SUPERFAMILY SSF56784 2 273 9.83E-53 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS13540 0fa0d6b87436bcf9fae94d329ce63c34 213 SUPERFAMILY SSF109604 10 107 1.64E-14 T 29-03-2018 CSW12_RS13540 0fa0d6b87436bcf9fae94d329ce63c34 213 SUPERFAMILY SSF109604 135 149 1.64E-14 T 29-03-2018 CSW12_RS13540 0fa0d6b87436bcf9fae94d329ce63c34 213 Pfam PF01966 HD domain 26 90 4.3E-6 T 29-03-2018 IPR006674 HD domain CSW12_RS13540 0fa0d6b87436bcf9fae94d329ce63c34 213 Gene3D G3DSA:1.10.3210.10 8 207 1.2E-13 T 29-03-2018 CSW12_RS13540 0fa0d6b87436bcf9fae94d329ce63c34 213 SMART SM00471 21 160 1.2E-5 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS17220 4169a7282bc08247796ea70309bcd30c 157 Pfam PF13241 Putative NAD(P)-binding 7 111 4.8E-24 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS17220 4169a7282bc08247796ea70309bcd30c 157 SUPERFAMILY SSF51735 3 102 3.94E-20 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS17220 4169a7282bc08247796ea70309bcd30c 157 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 5 152 1.5E-29 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS17220 4169a7282bc08247796ea70309bcd30c 157 Gene3D G3DSA:3.40.50.720 4 117 5.9E-20 T 29-03-2018 CSW12_RS17220 4169a7282bc08247796ea70309bcd30c 157 Gene3D G3DSA:3.30.160.110 118 145 1.5E-8 T 29-03-2018 CSW12_RS17220 4169a7282bc08247796ea70309bcd30c 157 SUPERFAMILY SSF75615 107 148 7.98E-6 T 29-03-2018 CSW12_RS22825 ec9993845f480b40a8a53cd6afe7a8fe 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 29-03-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 CSW12_RS22825 ec9993845f480b40a8a53cd6afe7a8fe 166 SUPERFAMILY SSF52833 3 160 2.09E-43 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS22825 ec9993845f480b40a8a53cd6afe7a8fe 166 Pfam PF08534 Redoxin 19 159 5.3E-24 T 29-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CSW12_RS22825 ec9993845f480b40a8a53cd6afe7a8fe 166 Gene3D G3DSA:3.40.30.10 8 164 3.5E-24 T 29-03-2018 CSW12_RS22825 ec9993845f480b40a8a53cd6afe7a8fe 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 163 38.266 T 29-03-2018 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 SUPERFAMILY SSF110849 36 173 8.89E-35 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 35 288 3.9E-115 T 29-03-2018 IPR023705 Nucleoid occlusion protein CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 Gene3D G3DSA:1.10.10.730 128 175 3.7E-18 T 29-03-2018 CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 Gene3D G3DSA:1.10.10.10 211 286 0.0093 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 SMART SM00470 37 127 6.7E-34 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 34 212 1.4E-59 T 29-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 288 39.198 T 29-03-2018 IPR023705 Nucleoid occlusion protein CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 Pfam PF02195 ParB-like nuclease domain 38 126 1.1E-26 T 29-03-2018 IPR003115 ParB/Sulfiredoxin CSW12_RS27270 a668902e04efb0d375dd78555605d3a5 290 Gene3D G3DSA:3.90.1530.10 24 127 1.0E-35 T 29-03-2018 CSW12_RS27905 46040fe68869878276491486e8873e3c 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 56 12.419 T 29-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS27905 46040fe68869878276491486e8873e3c 59 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 57 5.1E-21 T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS27905 46040fe68869878276491486e8873e3c 59 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 6 34 - T 29-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CSW12_RS27905 46040fe68869878276491486e8873e3c 59 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 4 59 2.4E-22 T 29-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CSW12_RS27905 46040fe68869878276491486e8873e3c 59 Gene3D G3DSA:1.20.5.1030 3 54 3.7E-20 T 29-03-2018 CSW12_RS10350 15505df808116b04a73726e3f573889e 163 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 14 160 2.0E-37 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CSW12_RS10350 15505df808116b04a73726e3f573889e 163 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS10350 15505df808116b04a73726e3f573889e 163 Pfam PF01066 CDP-alcohol phosphatidyltransferase 8 72 1.1E-15 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PIRSF PIRSF000513 4 268 1.2E-95 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 SUPERFAMILY SSF53613 11 267 3.9E-61 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 12 256 2.6E-94 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 Pfam PF02110 Hydroxyethylthiazole kinase family 12 254 5.6E-91 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 260 33.18 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 Gene3D G3DSA:3.40.1190.20 1 269 1.4E-56 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 3.1E-41 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 3.1E-41 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 3.1E-41 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 3.1E-41 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 3.1E-41 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS00770 f9a50de81a366e1c155c0868945523a4 269 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 163 180 3.1E-41 T 29-03-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Pfam PF02225 PA domain 460 540 5.9E-17 T 29-03-2018 IPR003137 PA domain CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 618 628 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 SUPERFAMILY SSF52743 204 425 7.59E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 SUPERFAMILY SSF52743 567 678 7.59E-85 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 SUPERFAMILY SSF49384 1078 1186 2.97E-6 T 29-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Gene3D G3DSA:2.60.40.680 1066 1229 5.7E-13 T 29-03-2018 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Pfam PF00082 Subtilase family 219 668 3.3E-66 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 SUPERFAMILY SSF52025 458 516 9.55E-19 T 29-03-2018 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 300 310 - T 29-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Gene3D G3DSA:3.40.50.200 188 686 1.8E-95 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 296 309 4.1E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 617 633 4.1E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 PRINTS PR00723 Subtilisin serine protease family (S8) signature 219 238 4.1E-21 T 29-03-2018 IPR015500 Peptidase S8, subtilisin-related CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 PIRSF PIRSF037844 1 1413 0.0 T 29-03-2018 IPR017292 Peptidase S8A, Vpr CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Pfam PF05922 Peptidase inhibitor I9 84 185 1.6E-9 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 224 235 - T 29-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Gene3D G3DSA:3.30.70.80 74 187 7.3E-8 T 29-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 SUPERFAMILY SSF63446 1326 1381 1.15E-6 T 29-03-2018 IPR016134 Dockerin domain GO:0000272 CSW12_RS15250 0ec953b4cc6382c5da61fa10a22377f8 1413 Gene3D G3DSA:2.60.40.1710 697 815 1.3E-8 T 29-03-2018 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 436 1.3E-149 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 Pfam PF01235 Sodium:alanine symporter family 52 448 7.4E-156 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 PRINTS PR00175 Sodium/alanine symporter signature 181 199 4.1E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 PRINTS PR00175 Sodium/alanine symporter signature 345 367 4.1E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 PRINTS PR00175 Sodium/alanine symporter signature 405 425 4.1E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 PRINTS PR00175 Sodium/alanine symporter signature 91 113 4.1E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 PRINTS PR00175 Sodium/alanine symporter signature 300 318 4.1E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS15500 6072850915c905ea62dfb712bf10ec6b 474 PRINTS PR00175 Sodium/alanine symporter signature 209 228 4.1E-51 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13990 0f8098e93a04f0401e63644d54b7b966 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 7.5E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS13990 0f8098e93a04f0401e63644d54b7b966 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 227 241 7.5E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS13990 0f8098e93a04f0401e63644d54b7b966 284 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 7.5E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS13990 0f8098e93a04f0401e63644d54b7b966 284 Pfam PF00561 alpha/beta hydrolase fold 25 266 5.9E-18 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS13990 0f8098e93a04f0401e63644d54b7b966 284 Gene3D G3DSA:3.40.50.1820 1 284 3.0E-41 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS13990 0f8098e93a04f0401e63644d54b7b966 284 SUPERFAMILY SSF53474 3 279 1.53E-55 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS02185 fd523a686b7aed508891154a6657cc39 118 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 16 115 5.6E-14 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CSW12_RS02185 fd523a686b7aed508891154a6657cc39 118 Pfam PF05521 Phage head-tail joining protein 16 112 9.6E-21 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CSW12_RS11675 e9c1a8ebc1244343609abafba77d8403 72 SUPERFAMILY SSF103365 5 71 1.18E-13 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CSW12_RS11675 e9c1a8ebc1244343609abafba77d8403 72 Pfam PF01139 tRNA-splicing ligase RtcB 38 71 4.7E-7 T 29-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 SUPERFAMILY SSF48264 22 391 6.94E-85 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 Gene3D G3DSA:1.10.630.10 6 395 1.3E-64 T 29-03-2018 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 29-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 88 99 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 194 216 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 320 335 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 292 319 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 134 150 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 342 351 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 351 362 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 PRINTS PR00359 B-class P450 signature 151 166 9.7E-40 T 29-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CSW12_RS14580 800edc67f9a083e87231fa285a9c229b 404 Pfam PF00067 Cytochrome P450 3 373 4.7E-38 T 29-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 SUPERFAMILY SSF88946 5 87 1.18E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 Pfam PF08281 Sigma-70, region 4 112 154 1.7E-11 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 Gene3D G3DSA:1.10.10.10 96 156 9.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 153 2.2E-27 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 SUPERFAMILY SSF88659 101 155 4.3E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 Gene3D G3DSA:1.10.1740.10 2 79 5.6E-17 T 29-03-2018 CSW12_RS26595 225ac7aeae497a9b6785418e55e85d48 167 Pfam PF04542 Sigma-70 region 2 9 76 9.3E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS05940 0e0998f2d182d26407bee3c97ddce2be 273 Pfam PF13256 Domain of unknown function (DUF4047) 33 157 7.3E-60 T 29-03-2018 IPR025120 Domain of unknown function DUF4047 CSW12_RS21560 fe0831f529ab518afbb80cb24f845182 92 Pfam PF06949 Protein of unknown function (DUF1292) 11 87 1.9E-16 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CSW12_RS21560 fe0831f529ab518afbb80cb24f845182 92 Hamap MF_01448 UPF0473 protein . 2 88 19.409 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CSW12_RS20135 65baab9803165b9caf94d9a77d723290 395 SUPERFAMILY SSF53383 5 390 1.25E-112 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS20135 65baab9803165b9caf94d9a77d723290 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 239 248 - T 29-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CSW12_RS20135 65baab9803165b9caf94d9a77d723290 395 Gene3D G3DSA:3.90.1150.10 288 393 9.4E-25 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20135 65baab9803165b9caf94d9a77d723290 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 384 1.1E-137 T 29-03-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CSW12_RS20135 65baab9803165b9caf94d9a77d723290 395 Gene3D G3DSA:3.40.640.10 119 287 2.0E-52 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS20135 65baab9803165b9caf94d9a77d723290 395 Pfam PF00155 Aminotransferase class I and II 42 384 6.9E-67 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS22525 252d43aca23c47c20b2300a2898b168d 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 3.0E-42 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CSW12_RS22525 252d43aca23c47c20b2300a2898b168d 130 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 7.7E-37 T 29-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CSW12_RS22525 252d43aca23c47c20b2300a2898b168d 130 Gene3D G3DSA:3.60.90.10 1 129 3.9E-43 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CSW12_RS22525 252d43aca23c47c20b2300a2898b168d 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 32.254 T 29-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CSW12_RS22525 252d43aca23c47c20b2300a2898b168d 130 SUPERFAMILY SSF56276 6 117 8.83E-42 T 29-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 62 125 2.7E-19 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 313 375 1.4E-16 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 135 289 1.4E-33 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 393 529 4.4E-11 T 29-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 SUPERFAMILY SSF55124 14 134 6.21E-30 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 SUPERFAMILY SSF56014 388 526 3.53E-32 T 29-03-2018 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 SUPERFAMILY SSF56014 135 290 3.14E-40 T 29-03-2018 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Gene3D G3DSA:3.30.413.10 387 533 3.6E-27 T 29-03-2018 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Gene3D G3DSA:3.90.480.10 256 376 7.0E-18 T 29-03-2018 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 SUPERFAMILY SSF55124 270 401 1.18E-21 T 29-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 PRINTS PR00397 Sirohaem Fe-binding site signature 434 452 2.7E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 PRINTS PR00397 Sirohaem Fe-binding site signature 390 408 2.7E-8 T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 434 450 - T 29-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CSW12_RS06700 b3100b462f25afe20f5eddebd5b893bc 540 Gene3D G3DSA:3.30.413.10 135 255 6.6E-26 T 29-03-2018 CSW12_RS16625 e57b383858d2260b16636fc5c634783e 300 SUPERFAMILY SSF161098 79 276 2.94E-9 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16625 e57b383858d2260b16636fc5c634783e 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 291 1.7E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16625 e57b383858d2260b16636fc5c634783e 300 Gene3D G3DSA:1.10.3720.10 8 297 3.6E-17 T 29-03-2018 CSW12_RS19505 1e28ce23353c2d7aacac82aa70459260 221 Pfam PF04239 Protein of unknown function (DUF421) 82 198 1.4E-32 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CSW12_RS19505 1e28ce23353c2d7aacac82aa70459260 221 Gene3D G3DSA:3.30.240.20 77 145 1.6E-19 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS19505 1e28ce23353c2d7aacac82aa70459260 221 Gene3D G3DSA:3.30.240.20 156 221 2.7E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS12465 06d51ee0c25fa9c9cb4368ac91c7d53c 303 SUPERFAMILY SSF103481 191 291 6.54E-15 T 29-03-2018 CSW12_RS12465 06d51ee0c25fa9c9cb4368ac91c7d53c 303 SUPERFAMILY SSF103481 39 142 9.94E-18 T 29-03-2018 CSW12_RS12465 06d51ee0c25fa9c9cb4368ac91c7d53c 303 Pfam PF00892 EamA-like transporter family 7 138 1.2E-28 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS12465 06d51ee0c25fa9c9cb4368ac91c7d53c 303 Pfam PF00892 EamA-like transporter family 153 287 1.4E-22 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 191 201 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 SUPERFAMILY SSF53448 325 342 1.64E-85 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 SUPERFAMILY SSF53448 5 264 1.64E-85 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 371 48.726 T 29-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 Pfam PF00483 Nucleotidyl transferase 9 261 2.1E-71 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 SUPERFAMILY SSF51161 234 375 4.4E-15 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 Gene3D G3DSA:3.90.550.10 1 267 1.5E-65 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 360 6.0E-147 T 29-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 100 108 - T 29-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CSW12_RS24090 a824ef92cb26b1a250e23a7441b1ae07 376 Gene3D G3DSA:2.160.10.10 268 375 3.0E-15 T 29-03-2018 CSW12_RS17485 8a7b2e26338e7dc6765327602724633e 295 Pfam PF00583 Acetyltransferase (GNAT) family 192 275 1.9E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17485 8a7b2e26338e7dc6765327602724633e 295 Pfam PF00583 Acetyltransferase (GNAT) family 30 109 9.2E-5 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17485 8a7b2e26338e7dc6765327602724633e 295 Gene3D G3DSA:3.40.630.30 143 295 3.1E-23 T 29-03-2018 CSW12_RS17485 8a7b2e26338e7dc6765327602724633e 295 SUPERFAMILY SSF55729 3 284 1.33E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17485 8a7b2e26338e7dc6765327602724633e 295 Gene3D G3DSA:3.40.630.30 6 130 8.9E-8 T 29-03-2018 CSW12_RS00855 430eef799d1e727965a1f41a5c9b3177 410 Pfam PF05977 Transmembrane secretion effector 5 403 3.1E-26 T 29-03-2018 IPR010290 Transmembrane secretion effector CSW12_RS00855 430eef799d1e727965a1f41a5c9b3177 410 Gene3D G3DSA:1.20.1250.20 203 396 2.6E-23 T 29-03-2018 CSW12_RS00855 430eef799d1e727965a1f41a5c9b3177 410 Gene3D G3DSA:1.20.1250.20 3 202 2.2E-26 T 29-03-2018 CSW12_RS00855 430eef799d1e727965a1f41a5c9b3177 410 SUPERFAMILY SSF103473 6 394 8.76E-51 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 Gene3D G3DSA:1.10.10.60 44 129 3.6E-10 T 29-03-2018 CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 54 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.5E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 SUPERFAMILY SSF48498 94 191 1.6E-5 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 Gene3D G3DSA:1.10.10.60 5 43 1.2E-16 T 29-03-2018 CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 1.3E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 Pfam PF08360 QacR-like protein, C-terminal region 67 168 2.5E-4 T 29-03-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 CSW12_RS04565 445dbaac139dfa3347420cffe642de6e 193 SUPERFAMILY SSF46689 5 65 1.64E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 SMART SM00977 388 464 4.2E-22 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 SUPERFAMILY SSF82829 219 328 1.1E-10 T 29-03-2018 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 SUPERFAMILY SSF52402 12 242 1.47E-60 T 29-03-2018 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 25 212 7.0E-60 T 29-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 Pfam PF11734 TilS substrate C-terminal domain 388 455 1.2E-14 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 Pfam PF09179 TilS substrate binding domain 261 329 3.6E-7 T 29-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 9 324 25.608 T 29-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 388 433 4.3E-20 T 29-03-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 SUPERFAMILY SSF56037 339 449 6.8E-18 T 29-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 Gene3D G3DSA:3.40.50.620 17 236 3.8E-48 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS27670 fe383dc16f36a8b1b7bef44722f6c2bc 476 Pfam PF01171 PP-loop family 25 208 8.7E-59 T 29-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CSW12_RS03625 d74b8cecc448e466a3acd2e47ff9994a 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS03625 d74b8cecc448e466a3acd2e47ff9994a 244 Pfam PF00005 ABC transporter 17 169 6.5E-35 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS03625 d74b8cecc448e466a3acd2e47ff9994a 244 Gene3D G3DSA:3.40.50.300 1 244 5.2E-80 T 29-03-2018 CSW12_RS03625 d74b8cecc448e466a3acd2e47ff9994a 244 SMART SM00382 26 217 3.5E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS03625 d74b8cecc448e466a3acd2e47ff9994a 244 PIRSF PIRSF039085 1 244 2.1E-117 T 29-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CSW12_RS03625 d74b8cecc448e466a3acd2e47ff9994a 244 SUPERFAMILY SSF52540 1 239 3.69E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27235 0691c9408547b4a0ba64425c6c68b231 96 Gene3D G3DSA:3.30.70.60 1 96 6.7E-33 T 29-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CSW12_RS27235 0691c9408547b4a0ba64425c6c68b231 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 24.045 T 29-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS27235 0691c9408547b4a0ba64425c6c68b231 96 SUPERFAMILY SSF54995 1 95 1.57E-35 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27235 0691c9408547b4a0ba64425c6c68b231 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 5.4E-33 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27235 0691c9408547b4a0ba64425c6c68b231 96 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 29-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CSW12_RS27235 0691c9408547b4a0ba64425c6c68b231 96 Pfam PF01250 Ribosomal protein S6 3 92 1.7E-30 T 29-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS16315 b15e4bb60cff384ccdd5662c45269abc 68 Pfam PF13619 KTSC domain 8 63 5.2E-16 T 29-03-2018 IPR025309 KTSC domain CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 176 2.7E-19 T 29-03-2018 CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 4 217 3.7E-120 T 29-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 Gene3D G3DSA:3.40.50.1000 58 219 2.4E-14 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 4 185 2.6E-52 T 29-03-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 1 215 50.938 T 29-03-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 SUPERFAMILY SSF56784 3 217 4.65E-56 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07500 4bdf1c7bf2069bad43430769f6a69c4f 219 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 177 7.9E-32 T 29-03-2018 CSW12_RS08870 f5d0fcf9d2945cdc9894d575dca9a118 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 2.3E-17 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS08870 f5d0fcf9d2945cdc9894d575dca9a118 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 187 2.7E-62 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CSW12_RS08870 f5d0fcf9d2945cdc9894d575dca9a118 192 PIRSF PIRSF000847 1 192 7.1E-51 T 29-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CSW12_RS08870 f5d0fcf9d2945cdc9894d575dca9a118 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS21880 9ff0f5e802ddb9a7cddf56f3924617e2 228 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 9 210 7.1E-35 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CSW12_RS21880 9ff0f5e802ddb9a7cddf56f3924617e2 228 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 211 21.34 T 29-03-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CSW12_RS21880 9ff0f5e802ddb9a7cddf56f3924617e2 228 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 108 207 8.7E-31 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CSW12_RS21880 9ff0f5e802ddb9a7cddf56f3924617e2 228 Gene3D G3DSA:2.160.20.70 97 214 1.6E-35 T 29-03-2018 CSW12_RS21880 9ff0f5e802ddb9a7cddf56f3924617e2 228 Gene3D G3DSA:3.30.750.50 9 96 2.3E-29 T 29-03-2018 CSW12_RS21880 9ff0f5e802ddb9a7cddf56f3924617e2 228 SUPERFAMILY SSF63848 106 207 3.27E-30 T 29-03-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CSW12_RS30455 88c510eaa5357289fab6d5aad059f0f3 1180 Gene3D G3DSA:3.90.1720.10 1057 1180 9.9E-32 T 29-03-2018 CSW12_RS30455 88c510eaa5357289fab6d5aad059f0f3 1180 Pfam PF13702 Lysozyme-like 877 1046 7.8E-40 T 29-03-2018 CSW12_RS30455 88c510eaa5357289fab6d5aad059f0f3 1180 Pfam PF00877 NlpC/P60 family 1070 1175 2.3E-25 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CSW12_RS30455 88c510eaa5357289fab6d5aad059f0f3 1180 SUPERFAMILY SSF54001 1055 1179 1.93E-34 T 29-03-2018 CSW12_RS30455 88c510eaa5357289fab6d5aad059f0f3 1180 Gene3D G3DSA:1.10.530.10 871 1033 1.9E-6 T 29-03-2018 CSW12_RS08840 c265f3d6dce5d85fbc17373319198e8f 424 Gene3D G3DSA:3.30.830.10 240 413 7.0E-31 T 29-03-2018 CSW12_RS08840 c265f3d6dce5d85fbc17373319198e8f 424 SUPERFAMILY SSF63411 12 232 1.26E-25 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS08840 c265f3d6dce5d85fbc17373319198e8f 424 Gene3D G3DSA:3.30.830.10 6 227 2.0E-25 T 29-03-2018 CSW12_RS08840 c265f3d6dce5d85fbc17373319198e8f 424 SUPERFAMILY SSF63411 243 411 1.25E-32 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS08840 c265f3d6dce5d85fbc17373319198e8f 424 Pfam PF05193 Peptidase M16 inactive domain 184 356 5.4E-27 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 Pfam PF00285 Citrate synthase, C-terminal domain 10 360 5.6E-114 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PIRSF PIRSF001369 1 371 2.8E-139 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 ProSitePatterns PS00480 Citrate synthase signature. 259 272 - T 29-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 Gene3D G3DSA:1.10.580.10 17 239 2.0E-66 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 Gene3D G3DSA:1.10.580.10 314 357 5.1E-7 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 SUPERFAMILY SSF48256 6 367 1.31E-121 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 330 344 3.2E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 177 192 3.2E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 252 272 3.2E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 128 141 3.2E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 199 227 3.2E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 PRINTS PR00143 Citrate synthase signature 310 326 3.2E-34 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS16290 c73ee89eb1632a96832c7e5d0ae76ef4 372 Gene3D G3DSA:1.10.230.10 240 313 5.7E-27 T 29-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CSW12_RS07620 c8a501289d4ccd2926191f51f6715404 242 Pfam PF13803 Domain of unknown function (DUF4184) 1 236 1.5E-74 T 29-03-2018 IPR025238 Protein of unknown function DUF4184 CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 SMART SM00382 33 241 1.3E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 Pfam PF00005 ABC transporter 25 183 5.7E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 2.6E-19 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 SUPERFAMILY SSF52540 4 254 3.55E-74 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 297 6.9E-15 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS05455 096db44fb4bfa3456e2706ff82a81a32 347 Gene3D G3DSA:3.40.50.300 1 334 2.1E-84 T 29-03-2018 CSW12_RS01935 823a9e173fa57d869058610d325ac1c8 478 Pfam PF14285 Domain of unknown function (DUF4367) 114 223 1.7E-10 T 29-03-2018 IPR025377 Domain of unknown function DUF4367 CSW12_RS01935 823a9e173fa57d869058610d325ac1c8 478 Gene3D G3DSA:2.60.40.1240 317 460 0.072 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS06635 3d70b5025e0577047f72039d19d9f1a1 101 SUPERFAMILY SSF141734 7 99 5.23E-45 T 29-03-2018 CSW12_RS06635 3d70b5025e0577047f72039d19d9f1a1 101 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 24 97 9.1E-36 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CSW12_RS06635 3d70b5025e0577047f72039d19d9f1a1 101 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 101 28.555 T 29-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CSW12_RS06635 3d70b5025e0577047f72039d19d9f1a1 101 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 47 101 2.0E-27 T 29-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CSW12_RS25815 cb31c8927f8ede9cfafae6662e354d42 385 Pfam PF01757 Acyltransferase family 10 343 1.7E-29 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS00995 435080583d00f4f1802a949b7de4f5de 138 Gene3D G3DSA:2.30.110.10 1 138 1.1E-23 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS00995 435080583d00f4f1802a949b7de4f5de 138 SUPERFAMILY SSF50475 3 128 5.05E-29 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS00995 435080583d00f4f1802a949b7de4f5de 138 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 5 128 1.0E-18 T 29-03-2018 CSW12_RS12975 3a6b0d255c2c6bc33f0cbd78dbf31b0c 273 Pfam PF00753 Metallo-beta-lactamase superfamily 76 228 2.8E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12975 3a6b0d255c2c6bc33f0cbd78dbf31b0c 273 Gene3D G3DSA:3.60.15.10 25 269 4.7E-18 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12975 3a6b0d255c2c6bc33f0cbd78dbf31b0c 273 SMART SM00849 75 245 2.3E-7 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS12975 3a6b0d255c2c6bc33f0cbd78dbf31b0c 273 SUPERFAMILY SSF56281 58 226 2.17E-25 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS17025 6a0995f78404caaf0303a63dd0d6ff66 255 SUPERFAMILY SSF81606 30 228 2.35E-8 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS17025 6a0995f78404caaf0303a63dd0d6ff66 255 Gene3D G3DSA:3.60.40.10 11 249 2.2E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS02370 cf9d9a4c78d1bb70233c9e87bae492ed 68 SUPERFAMILY SSF47413 3 66 5.91E-16 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02370 cf9d9a4c78d1bb70233c9e87bae492ed 68 SMART SM00530 8 63 4.9E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02370 cf9d9a4c78d1bb70233c9e87bae492ed 68 Gene3D G3DSA:1.10.3100.10 1 66 2.7E-17 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS02370 cf9d9a4c78d1bb70233c9e87bae492ed 68 Pfam PF01381 Helix-turn-helix 11 63 1.9E-12 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS18655 cf51656e85dfcaaf3b3aea83a185af07 228 Pfam PF04239 Protein of unknown function (DUF421) 88 205 1.3E-31 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CSW12_RS18655 cf51656e85dfcaaf3b3aea83a185af07 228 Gene3D G3DSA:3.30.240.20 82 152 2.5E-23 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS18655 cf51656e85dfcaaf3b3aea83a185af07 228 Gene3D G3DSA:3.30.240.20 171 226 8.3E-17 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SMART SM00316 187 257 1.0E-28 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SMART SM00316 272 343 3.2E-26 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SMART SM00316 16 85 5.5E-14 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SMART SM00316 101 168 1.0E-9 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SUPERFAMILY SSF50249 257 347 1.12E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SUPERFAMILY SSF50249 88 170 4.49E-16 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 82 101 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 18 36 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 209 230 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 36 50 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 152 172 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 326 344 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 106 122 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 123 140 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 PRINTS PR00681 Ribosomal protein S1 signature 287 306 4.7E-56 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Pfam PF00575 S1 RNA binding domain 15 82 3.7E-14 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Pfam PF00575 S1 RNA binding domain 100 168 8.5E-15 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Pfam PF00575 S1 RNA binding domain 271 343 4.5E-24 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Pfam PF00575 S1 RNA binding domain 186 257 9.2E-26 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SUPERFAMILY SSF50249 186 271 6.08E-28 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 SUPERFAMILY SSF50249 5 110 1.49E-19 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Gene3D G3DSA:2.40.50.140 178 262 6.9E-29 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Gene3D G3DSA:2.40.50.140 268 349 2.6E-24 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Gene3D G3DSA:2.40.50.140 96 174 4.4E-12 T 29-03-2018 CSW12_RS07095 d250d87534737707d7244f16b068e57c 382 Gene3D G3DSA:2.40.50.140 8 91 4.0E-16 T 29-03-2018 CSW12_RS16015 39015009b49908318b5e5fcbfa91bb7c 217 Pfam PF00753 Metallo-beta-lactamase superfamily 22 202 2.3E-24 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16015 39015009b49908318b5e5fcbfa91bb7c 217 SUPERFAMILY SSF56281 1 209 4.19E-44 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16015 39015009b49908318b5e5fcbfa91bb7c 217 Gene3D G3DSA:3.60.15.10 1 215 1.2E-34 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS16015 39015009b49908318b5e5fcbfa91bb7c 217 SMART SM00849 18 202 3.4E-28 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS21240 4484840451979ce20427cfca9f863e42 44 Pfam PF14141 YqzM-like protein 2 43 1.7E-25 T 29-03-2018 IPR025416 YqzM-like protein CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 Gene3D G3DSA:1.20.1250.20 257 528 1.6E-35 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 Gene3D G3DSA:1.20.1250.20 7 193 2.1E-35 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 4.3E-11 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 300 324 4.3E-11 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 4.3E-11 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 4.3E-11 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 4.3E-11 T 29-03-2018 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 SUPERFAMILY SSF103473 487 528 4.97E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 SUPERFAMILY SSF103473 6 200 4.97E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 SUPERFAMILY SSF103473 247 417 4.97E-79 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 510 3.7E-90 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS02020 707d8e4d6d1f371efd07fb7b1fd9cd64 537 Pfam PF07690 Major Facilitator Superfamily 16 407 2.9E-54 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS20360 724d9dab2cace0cfc6a45f0b0d6ca52f 392 Pfam PF01098 Cell cycle protein 14 383 2.7E-86 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CSW12_RS20360 724d9dab2cace0cfc6a45f0b0d6ca52f 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 342 366 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CSW12_RS20660 db1beabd68667c02443858742e7ca966 110 Pfam PF00893 Small Multidrug Resistance protein 1 90 1.2E-20 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CSW12_RS20660 db1beabd68667c02443858742e7ca966 110 SUPERFAMILY SSF103481 5 99 1.03E-15 T 29-03-2018 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 154 166 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 Gene3D G3DSA:1.20.1250.20 8 224 1.6E-28 T 29-03-2018 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 SUPERFAMILY SSF103473 10 458 2.22E-45 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 Gene3D G3DSA:1.20.1250.20 244 460 2.3E-20 T 29-03-2018 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 Pfam PF00854 POT family 245 428 1.2E-36 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 Pfam PF00854 POT family 92 214 1.3E-28 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 243 460 1.5E-44 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CSW12_RS02645 7ab40b0e8c3ea84222061badd7ad39e1 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 226 4.1E-57 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CSW12_RS04925 444415c5bf6ac77ae5f5628e255e5788 164 Gene3D G3DSA:1.25.40.10 8 144 4.9E-4 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS01735 eeca391871c92e58ceed2b825ca24900 420 Pfam PF12229 Putative peptidoglycan binding domain 87 200 1.1E-11 T 29-03-2018 IPR022029 Putative peptidoglycan binding domain CSW12_RS01735 eeca391871c92e58ceed2b825ca24900 420 Pfam PF04294 VanW like protein 238 366 1.9E-45 T 29-03-2018 IPR007391 Vancomycin resistance VanW CSW12_RS15585 7341016ac7a1a5f34f61d45703a91db2 83 Gene3D G3DSA:1.10.10.10 2 69 7.0E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15585 7341016ac7a1a5f34f61d45703a91db2 83 SMART SM00421 2 59 1.9E-6 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS15585 7341016ac7a1a5f34f61d45703a91db2 83 SUPERFAMILY SSF46894 4 66 1.9E-13 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS15585 7341016ac7a1a5f34f61d45703a91db2 83 Pfam PF00196 Bacterial regulatory proteins, luxR family 4 55 3.6E-8 T 29-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CSW12_RS12455 813caa899eb4af1a6ec82e4fd0e00bee 146 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 144 1.6E-41 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CSW12_RS12455 813caa899eb4af1a6ec82e4fd0e00bee 146 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 146 28.348 T 29-03-2018 IPR003791 Protein of unknown function UPF0178 CSW12_RS25435 2fceab70dcaa2dc7046903637f81415f 68 Gene3D G3DSA:1.20.140.40 2 65 2.4E-4 T 29-03-2018 CSW12_RS25435 2fceab70dcaa2dc7046903637f81415f 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 3.0E-18 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 Gene3D G3DSA:1.10.1660.10 56 122 3.3E-7 T 29-03-2018 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 SUPERFAMILY SSF46955 1 115 1.06E-22 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 SMART SM00422 1 69 4.4E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.4E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.4E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.4E-8 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 Gene3D G3DSA:1.10.1660.10 1 55 2.7E-19 T 29-03-2018 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 Pfam PF13411 MerR HTH family regulatory protein 2 68 5.2E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25575 a4eb9ad43e8a2f3ef322e3abb022eedf 122 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 Gene3D G3DSA:3.40.1160.10 2 313 4.9E-61 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 267 282 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PRINTS PR01469 Bacterial carbamate kinase signature 212 227 2.6E-65 T 29-03-2018 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 SUPERFAMILY SSF53633 4 311 6.28E-89 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 Pfam PF00696 Amino acid kinase family 5 293 1.2E-33 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 PIRSF PIRSF000723 2 313 5.1E-127 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CSW12_RS00715 5bf3cb460e1f0367c0a51f8f16435b6a 320 TIGRFAM TIGR00746 arcC: carbamate kinase 4 313 1.2E-135 T 29-03-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 Gene3D G3DSA:1.10.10.10 1 83 1.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 SUPERFAMILY SSF53850 91 245 2.35E-7 T 29-03-2018 CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 SUPERFAMILY SSF46785 1 106 2.48E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.4E-17 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS18185 5e6871fdeab52646336f2889141f1399 262 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.3E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 191 4.6E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 198 4.9E-27 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 Gene3D G3DSA:3.40.50.1000 90 234 2.1E-30 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 225 2.7E-66 T 29-03-2018 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 199 8.3E-9 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 Gene3D G3DSA:1.10.150.240 16 89 3.6E-21 T 29-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 1.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 1.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 1.1E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS11240 4953362c05bb70c1fa26e144353cc2c8 236 SUPERFAMILY SSF56784 2 226 3.81E-46 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS13670 9b743eaca2aa007f9f7a35810c1d4b21 121 Pfam PF04237 YjbR 13 106 4.5E-23 T 29-03-2018 IPR007351 Uncharacterised protein YjbR CSW12_RS13670 9b743eaca2aa007f9f7a35810c1d4b21 121 SUPERFAMILY SSF142906 5 119 2.09E-37 T 29-03-2018 CSW12_RS27635 8875d8cb2d1fadbf6db08196d8c2d09c 102 PIRSF PIRSF011576 1 102 1.6E-58 T 29-03-2018 IPR012504 Sporulation protein YabP CSW12_RS27635 8875d8cb2d1fadbf6db08196d8c2d09c 102 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 18 102 5.0E-34 T 29-03-2018 IPR012504 Sporulation protein YabP CSW12_RS27635 8875d8cb2d1fadbf6db08196d8c2d09c 102 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 19 102 2.6E-35 T 29-03-2018 IPR012504 Sporulation protein YabP CSW12_RS27635 8875d8cb2d1fadbf6db08196d8c2d09c 102 Pfam PF07873 YabP family 19 84 3.6E-20 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CSW12_RS12340 d61ce51879055cab5f79db7d384ddbbc 191 SUPERFAMILY SSF53335 2 188 5.03E-33 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS12340 d61ce51879055cab5f79db7d384ddbbc 191 Gene3D G3DSA:3.40.50.150 18 180 1.7E-6 T 29-03-2018 CSW12_RS12340 d61ce51879055cab5f79db7d384ddbbc 191 Pfam PF04989 Cephalosporin hydroxylase 3 190 3.3E-69 T 29-03-2018 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 CSW12_RS17520 db0c64870a1caa7173d4ab4669628d4f 196 Gene3D G3DSA:3.40.50.1240 1 196 1.1E-44 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS17520 db0c64870a1caa7173d4ab4669628d4f 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 190 1.1E-44 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS17520 db0c64870a1caa7173d4ab4669628d4f 196 PIRSF PIRSF000709 1 184 1.4E-14 T 29-03-2018 CSW12_RS17520 db0c64870a1caa7173d4ab4669628d4f 196 SUPERFAMILY SSF53254 1 194 4.32E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS17520 db0c64870a1caa7173d4ab4669628d4f 196 SMART SM00855 2 150 9.0E-20 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS13635 8839e14ee7f430c0570d455113aec6bb 111 Pfam PF06108 Protein of unknown function (DUF952) 6 93 1.2E-22 T 29-03-2018 IPR009297 Protein of unknown function DUF952 CSW12_RS13635 8839e14ee7f430c0570d455113aec6bb 111 SUPERFAMILY SSF56399 2 105 6.91E-28 T 29-03-2018 CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 Pfam PF00005 ABC transporter 376 525 4.7E-36 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 SUPERFAMILY SSF52540 349 596 2.72E-91 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 SMART SM00382 385 571 4.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 SUPERFAMILY SSF90123 31 343 5.23E-82 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 Gene3D G3DSA:1.20.1560.10 8 344 3.6E-80 T 29-03-2018 CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 Pfam PF00664 ABC transporter transmembrane region 43 314 3.0E-56 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS15865 72fd8e52b5409d0e1c4bf0443c02ece1 598 Gene3D G3DSA:3.40.50.300 345 597 2.2E-72 T 29-03-2018 CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 Gene3D G3DSA:3.40.50.1000 1 113 2.8E-16 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 Gene3D G3DSA:3.40.50.1000 164 283 6.9E-21 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 251 7.1E-26 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 278 1.9E-76 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 3 278 9.9E-57 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 SUPERFAMILY SSF56784 2 282 2.03E-67 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 29-03-2018 CSW12_RS14570 2f04630f35c4dde8fbba2d7d2e8072bc 283 ProSitePatterns PS01229 Hypothetical cof family signature 2. 232 254 - T 29-03-2018 CSW12_RS12375 f381d1a8b1313bd121808d4319227287 661 Pfam PF02687 FtsX-like permease family 562 649 3.8E-12 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS12375 f381d1a8b1313bd121808d4319227287 661 Pfam PF02687 FtsX-like permease family 266 362 4.4E-11 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS12375 f381d1a8b1313bd121808d4319227287 661 Pfam PF12704 MacB-like periplasmic core domain 20 166 4.6E-6 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CSW12_RS12375 f381d1a8b1313bd121808d4319227287 661 Gene3D G3DSA:1.20.1250.20 285 653 2.7E-4 T 29-03-2018 CSW12_RS08410 c3cca543446ff4e5da6aa879e24955d4 87 Pfam PF04025 Domain of unknown function (DUF370) 5 77 5.3E-36 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CSW12_RS08410 c3cca543446ff4e5da6aa879e24955d4 87 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 6 78 2.0E-36 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CSW12_RS08410 c3cca543446ff4e5da6aa879e24955d4 87 Hamap MF_01503 UPF0296 protein . 3 86 28.228 T 29-03-2018 IPR007169 Uncharacterised protein family UPF0296 CSW12_RS02735 c031d07415ca51dc122d3cff3f3ea4c8 65 Pfam PF11755 Protein of unknown function (DUF3311) 6 62 7.5E-17 T 29-03-2018 IPR021741 Protein of unknown function DUF3311 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 SUPERFAMILY SSF81464 19 120 8.67E-23 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 16 241 1.1E-91 T 29-03-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 Gene3D G3DSA:1.10.287.90 30 116 7.4E-25 T 29-03-2018 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 Gene3D G3DSA:2.60.40.420 117 280 2.5E-39 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 111 6.1E-10 T 29-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 PIRSF PIRSF000292 2 291 8.4E-104 T 29-03-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 SUPERFAMILY SSF49503 128 274 2.74E-42 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 192 209 2.9E-6 T 29-03-2018 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 87 99 2.9E-6 T 29-03-2018 CSW12_RS02715 b387bf67fb5c911a798339952a338ee9 291 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 2.9E-6 T 29-03-2018 CSW12_RS28010 c4d4b3e291d33e5ac0c9919282ebc665 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 5.2E-38 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28010 c4d4b3e291d33e5ac0c9919282ebc665 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 29-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28010 c4d4b3e291d33e5ac0c9919282ebc665 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.666 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28010 c4d4b3e291d33e5ac0c9919282ebc665 113 SUPERFAMILY SSF54843 1 112 5.76E-45 T 29-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28010 c4d4b3e291d33e5ac0c9919282ebc665 113 Gene3D G3DSA:3.90.470.10 1 113 9.9E-45 T 29-03-2018 CSW12_RS28010 c4d4b3e291d33e5ac0c9919282ebc665 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.3E-53 T 29-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 Gene3D G3DSA:3.10.290.10 2 61 1.5E-14 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 Gene3D G3DSA:3.30.2350.10 62 237 3.7E-34 T 29-03-2018 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 221 2.1E-47 T 29-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 SMART SM00363 4 64 3.4E-10 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 29-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 Pfam PF01479 S4 domain 5 49 1.5E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 SUPERFAMILY SSF55174 4 57 1.68E-12 T 29-03-2018 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 Pfam PF00849 RNA pseudouridylate synthase 64 190 3.3E-14 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS16105 d4083a3be605f2d80ccd7c86dc4022bb 238 SUPERFAMILY SSF55120 61 225 1.53E-39 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS24500 5cf41f6d242543a24b5ba7f3ca0d011d 109 SUPERFAMILY SSF140500 53 104 6.54E-15 T 29-03-2018 CSW12_RS24500 5cf41f6d242543a24b5ba7f3ca0d011d 109 Pfam PF09388 Spo0E like sporulation regulatory protein 58 96 5.8E-14 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CSW12_RS11210 dd91983ed5b9886796e25f7816e0b6e9 84 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 1 84 7.0E-36 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CSW12_RS11210 dd91983ed5b9886796e25f7816e0b6e9 84 Pfam PF10852 Protein of unknown function (DUF2651) 6 78 4.8E-29 T 29-03-2018 IPR020258 Uncharacterised protein family YbeF CSW12_RS15675 c6148586a75ee85fba5989424b3964cc 260 Gene3D G3DSA:3.40.50.150 3 240 4.1E-18 T 29-03-2018 CSW12_RS15675 c6148586a75ee85fba5989424b3964cc 260 Pfam PF08241 Methyltransferase domain 63 158 1.6E-16 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS15675 c6148586a75ee85fba5989424b3964cc 260 SUPERFAMILY SSF53335 50 252 3.45E-26 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS28310 e797b424b83f31bf3c61c0c6f9f35269 433 Pfam PF16781 Domain of unknown function (DUF5068) 71 236 3.3E-14 T 29-03-2018 IPR031888 Protein of unknown function DUF5068 CSW12_RS28310 e797b424b83f31bf3c61c0c6f9f35269 433 Gene3D G3DSA:2.60.40.1240 289 432 1.3E-12 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS28310 e797b424b83f31bf3c61c0c6f9f35269 433 Gene3D G3DSA:2.60.40.1240 102 262 4.8E-10 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 SUPERFAMILY SSF55120 74 301 1.67E-80 T 29-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 SUPERFAMILY SSF55174 16 102 6.73E-15 T 29-03-2018 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 Pfam PF01479 S4 domain 16 62 8.4E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 12 301 6.7E-107 T 29-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 SMART SM00363 16 75 8.0E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 29-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 Gene3D G3DSA:3.30.2350.10 80 302 4.8E-74 T 29-03-2018 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 Gene3D G3DSA:3.10.290.10 2 73 5.3E-20 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS08295 da433cfcbdb4442a6073e9b653cfa07b 302 Pfam PF00849 RNA pseudouridylate synthase 89 242 2.5E-36 T 29-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CSW12_RS03745 3f469d20ecae7d17a1ee17ef298ffa6c 506 PIRSF PIRSF038958 1 506 8.3E-81 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CSW12_RS03745 3f469d20ecae7d17a1ee17ef298ffa6c 506 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 353 494 4.5E-19 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CSW12_RS03745 3f469d20ecae7d17a1ee17ef298ffa6c 506 Pfam PF01943 Polysaccharide biosynthesis protein 6 300 2.2E-34 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS11975 1bb4085242b338f5c5503ec4cf949f25 145 Gene3D G3DSA:3.10.180.10 1 129 8.2E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS11975 1bb4085242b338f5c5503ec4cf949f25 145 SUPERFAMILY SSF54593 1 120 5.37E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS11975 1bb4085242b338f5c5503ec4cf949f25 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 7.1E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS02065 7421ddb5417cd694ea70ce77f771ed56 90 Pfam PF05595 Domain of unknown function (DUF771) 31 89 2.0E-9 T 29-03-2018 IPR008489 Protein of unknown function DUF771 CSW12_RS23135 d2ac92a32eb5ed2894a9de5a7e30aa2e 114 Gene3D G3DSA:3.40.1580.10 8 112 3.9E-4 T 29-03-2018 CSW12_RS02595 59877aa285620097916caad965bc0b4e 383 Pfam PF06271 RDD family 215 367 3.9E-13 T 29-03-2018 IPR010432 RDD CSW12_RS02595 59877aa285620097916caad965bc0b4e 383 Pfam PF04892 VanZ like family 49 194 1.4E-22 T 29-03-2018 IPR006976 VanZ-like CSW12_RS02595 59877aa285620097916caad965bc0b4e 383 PIRSF PIRSF031578 1 383 2.1E-151 T 29-03-2018 IPR021192 Uncharacterised conserved protein UCP031578, VanZ/RDD-type CSW12_RS02755 80aa71f6faa108427d4990fab77858c0 390 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 383 7.9E-106 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS02755 80aa71f6faa108427d4990fab77858c0 390 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 214 382 2.9E-34 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 3 314 49.755 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 SUPERFAMILY SSF52096 5 313 1.57E-103 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 316 2.7E-158 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 4 146 6.1E-66 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 Gene3D G3DSA:3.90.226.10 7 313 6.3E-68 T 29-03-2018 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 132 148 7.3E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 167 180 7.3E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 86 97 7.3E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 195 204 7.3E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 151 164 7.3E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22630 5410630b2e0e7fb58f46661829380d68 324 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 111 129 7.3E-47 T 29-03-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS03820 5f07097f25e24fc8df94b0d90eb54b44 325 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 317 3.0E-83 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CSW12_RS03820 5f07097f25e24fc8df94b0d90eb54b44 325 Gene3D G3DSA:3.30.1780.10 1 137 2.7E-39 T 29-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CSW12_RS03820 5f07097f25e24fc8df94b0d90eb54b44 325 PIRSF PIRSF001439 1 325 6.1E-93 T 29-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CSW12_RS03820 5f07097f25e24fc8df94b0d90eb54b44 325 Gene3D G3DSA:3.40.50.720 138 298 3.9E-36 T 29-03-2018 CSW12_RS03820 5f07097f25e24fc8df94b0d90eb54b44 325 SUPERFAMILY SSF51735 1 325 4.22E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 Pfam PF02073 Thermophilic metalloprotease (M29) 4 407 9.3E-177 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 3.8E-74 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 SUPERFAMILY SSF144052 3 408 1.03E-152 T 29-03-2018 CSW12_RS00470 d4a972d547d1f78bc722c29d0ca24a1f 409 Gene3D G3DSA:3.40.1830.10 3 179 2.2E-62 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CSW12_RS03815 65fc02730218a9d87dc4a0ce7498f1eb 334 Gene3D G3DSA:3.10.310.10 154 309 1.6E-54 T 29-03-2018 CSW12_RS03815 65fc02730218a9d87dc4a0ce7498f1eb 334 SUPERFAMILY SSF54506 1 331 4.04E-106 T 29-03-2018 CSW12_RS03815 65fc02730218a9d87dc4a0ce7498f1eb 334 PIRSF PIRSF029792 1 334 1.2E-134 T 29-03-2018 IPR008794 Proline racemase family CSW12_RS03815 65fc02730218a9d87dc4a0ce7498f1eb 334 Pfam PF05544 Proline racemase 10 331 4.8E-103 T 29-03-2018 IPR008794 Proline racemase family CSW12_RS03815 65fc02730218a9d87dc4a0ce7498f1eb 334 Gene3D G3DSA:3.10.310.10 1 153 1.3E-33 T 29-03-2018 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 Pfam PF00919 Uncharacterized protein family UPF0004 67 168 1.8E-30 T 29-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 SUPERFAMILY SSF102114 198 431 1.57E-64 T 29-03-2018 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 Gene3D G3DSA:3.80.30.20 209 443 2.2E-56 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 67 502 4.3E-201 T 29-03-2018 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 Pfam PF04055 Radical SAM superfamily 215 386 5.4E-33 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 Pfam PF01938 TRAM domain 441 502 4.0E-13 T 29-03-2018 IPR002792 TRAM domain CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 66 503 74.32 T 29-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 SMART SM00729 211 429 5.4E-66 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 67 499 4.7E-162 T 29-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CSW12_RS08920 2e3efea32557ec582c3344d6cbbaeab1 509 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 215 235 - T 29-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CSW12_RS06980 95036ececba48396a26fd6e30c2506c9 193 Pfam PF01923 Cobalamin adenosyltransferase 4 166 1.7E-57 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CSW12_RS06980 95036ececba48396a26fd6e30c2506c9 193 Gene3D G3DSA:1.20.1200.10 12 185 6.6E-59 T 29-03-2018 CSW12_RS06980 95036ececba48396a26fd6e30c2506c9 193 SUPERFAMILY SSF89028 1 178 1.63E-64 T 29-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CSW12_RS06980 95036ececba48396a26fd6e30c2506c9 193 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 179 6.0E-94 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CSW12_RS06980 95036ececba48396a26fd6e30c2506c9 193 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 177 2.3E-63 T 29-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 Gene3D G3DSA:2.40.50.100 120 161 2.8E-15 T 29-03-2018 CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 SUPERFAMILY SSF51230 84 160 3.53E-23 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 90 103 1.2E-15 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 107 121 1.2E-15 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 122 135 1.2E-15 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 Pfam PF00364 Biotin-requiring enzyme 87 158 8.0E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 3 161 6.7E-55 T 29-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CSW12_RS20510 b9264b36127ad44f5b7083ccee255493 162 Gene3D G3DSA:2.40.50.100 87 119 0.0035 T 29-03-2018 CSW12_RS21680 2af948393385837709dae5b269c1eebf 170 Pfam PF00156 Phosphoribosyl transferase domain 31 148 7.8E-15 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS21680 2af948393385837709dae5b269c1eebf 170 Gene3D G3DSA:3.40.50.2020 1 168 3.5E-37 T 29-03-2018 CSW12_RS21680 2af948393385837709dae5b269c1eebf 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.436 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CSW12_RS21680 2af948393385837709dae5b269c1eebf 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 4 167 1.0E-67 T 29-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CSW12_RS21680 2af948393385837709dae5b269c1eebf 170 SUPERFAMILY SSF53271 3 163 3.12E-48 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS04250 dd44d3889712f2cc284835120d4f1fd6 154 Gene3D G3DSA:3.40.190.10 1 152 3.7E-4 T 29-03-2018 CSW12_RS22730 93706a4f59434babac5dda34f15d288d 110 SUPERFAMILY SSF51182 15 97 1.11E-17 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS22730 93706a4f59434babac5dda34f15d288d 110 Gene3D G3DSA:2.60.120.10 1 105 1.0E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS22730 93706a4f59434babac5dda34f15d288d 110 Pfam PF07883 Cupin domain 40 88 5.7E-14 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS12950 f806fb174987802a8c579321ddcccaa1 657 PIRSF PIRSF005091 1 626 7.3E-195 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CSW12_RS12950 f806fb174987802a8c579321ddcccaa1 657 Gene3D G3DSA:3.40.720.10 244 552 1.1E-40 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS12950 f806fb174987802a8c579321ddcccaa1 657 Pfam PF00884 Sulfatase 253 541 2.6E-39 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CSW12_RS12950 f806fb174987802a8c579321ddcccaa1 657 SUPERFAMILY SSF53649 250 644 2.99E-83 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS19670 0ddb2035c407cb1731aaa23aa31e1b8b 46 Pfam PF13040 Fur-regulated basic protein B 2 39 1.1E-14 T 29-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS CSW12_RS19670 0ddb2035c407cb1731aaa23aa31e1b8b 46 Gene3D G3DSA:1.10.10.440 1 41 0.0011 T 29-03-2018 CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 Gene3D G3DSA:3.40.50.2300 1 124 1.5E-38 T 29-03-2018 CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 219 1.7E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 SMART SM00862 148 219 4.7E-24 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 SUPERFAMILY SSF52172 1 180 2.99E-44 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 SMART SM00448 4 114 7.9E-44 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 Pfam PF00072 Response regulator receiver domain 6 114 7.7E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS14090 cf0b90cd2becc1b43783416e65d71151 221 Gene3D G3DSA:1.10.10.10 125 221 1.4E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30785 9027346c66dc1374c51e7d9012e7d70d 205 Pfam PF13814 Replication-relaxation 16 170 1.2E-12 T 29-03-2018 IPR025855 Plasmid replication-relaxation CSW12_RS15080 afc2dd74a0b21755df311f4f7edb46c1 186 Pfam PF13302 Acetyltransferase (GNAT) domain 14 153 2.0E-28 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS15080 afc2dd74a0b21755df311f4f7edb46c1 186 Gene3D G3DSA:3.40.630.30 1 186 4.8E-26 T 29-03-2018 CSW12_RS15080 afc2dd74a0b21755df311f4f7edb46c1 186 SUPERFAMILY SSF55729 8 179 4.94E-43 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Gene3D G3DSA:3.30.460.10 154 246 8.7E-27 T 29-03-2018 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SMART SM00483 2 316 9.9E-87 T 29-03-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 PIRSF PIRSF005047 3 572 1.8E-242 T 29-03-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SUPERFAMILY SSF47802 2 79 7.19E-20 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Gene3D G3DSA:1.10.150.20 88 148 7.8E-12 T 29-03-2018 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Pfam PF14716 Helix-hairpin-helix domain 6 71 8.7E-20 T 29-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Gene3D G3DSA:3.30.210.10 261 326 5.0E-20 T 29-03-2018 IPR029398 DNA polymerase beta, thumb domain CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SUPERFAMILY SSF81301 154 316 9.81E-46 T 29-03-2018 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Pfam PF02811 PHP domain 339 466 3.9E-10 T 29-03-2018 IPR004013 PHP domain GO:0003824 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SUPERFAMILY SSF89550 338 567 9.29E-57 T 29-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Gene3D G3DSA:3.20.20.140 330 572 3.7E-50 T 29-03-2018 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Pfam PF14791 DNA polymerase beta thumb 255 316 1.8E-19 T 29-03-2018 IPR029398 DNA polymerase beta, thumb domain CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SMART SM00278 50 69 5.8 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SMART SM00278 90 109 56.0 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SMART SM00278 125 144 6.8 T 29-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SMART SM00481 338 417 1.5E-21 T 29-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Pfam PF14520 Helix-hairpin-helix domain 92 145 2.5E-6 T 29-03-2018 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 SUPERFAMILY SSF158702 48 145 1.78E-8 T 29-03-2018 CSW12_RS22375 670e3b877ddd4a4ebe506fed1589cd80 572 Gene3D G3DSA:1.10.150.110 1 84 1.6E-19 T 29-03-2018 CSW12_RS04750 eb9c9d791d814e0634829c74add23ed4 42 Pfam PF14149 YhfH-like protein 3 38 1.2E-20 T 29-03-2018 IPR025432 YhfH-like protein CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 Gene3D G3DSA:3.30.470.20 96 239 4.0E-56 T 29-03-2018 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 Gene3D G3DSA:3.40.50.261 240 385 2.0E-42 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 PIRSF PIRSF001554 1 386 8.1E-157 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 SUPERFAMILY SSF56059 1 238 4.52E-86 T 29-03-2018 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 Pfam PF00549 CoA-ligase 262 381 1.3E-26 T 29-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 SUPERFAMILY SSF52210 241 385 8.11E-55 T 29-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 Pfam PF08442 ATP-grasp domain 2 202 1.3E-83 T 29-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 44.944 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 384 2.9E-166 T 29-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CSW12_RS08595 42ce4abcb3c19b268db684ae0b01422f 386 Gene3D G3DSA:3.30.1490.20 21 95 8.6E-28 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 SMART SM00967 5 79 5.1E-22 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 242 8.8E-83 T 29-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 SUPERFAMILY SSF75217 67 243 1.05E-48 T 29-03-2018 IPR029028 Alpha/beta knot methyltransferases CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 SUPERFAMILY SSF55315 3 76 4.0E-18 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 Gene3D G3DSA:3.30.1330.30 1 74 5.6E-17 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 79 3.6E-22 T 29-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 Pfam PF00588 SpoU rRNA Methylase family 96 236 1.8E-38 T 29-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CSW12_RS27885 2f296062777f7ebc122bbc900b3fadd9 247 Gene3D G3DSA:3.40.1280.10 77 247 2.3E-46 T 29-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CSW12_RS28135 130d703805aef3ddf286cbee1bcbd8ea 293 Gene3D G3DSA:3.40.50.300 2 260 7.9E-65 T 29-03-2018 CSW12_RS28135 130d703805aef3ddf286cbee1bcbd8ea 293 Pfam PF00005 ABC transporter 24 174 1.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28135 130d703805aef3ddf286cbee1bcbd8ea 293 SUPERFAMILY SSF52540 19 237 1.7E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28135 130d703805aef3ddf286cbee1bcbd8ea 293 SMART SM00382 32 223 6.7E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28135 130d703805aef3ddf286cbee1bcbd8ea 293 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 1.4E-122 T 29-03-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 CSW12_RS28135 130d703805aef3ddf286cbee1bcbd8ea 293 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS08845 d00b24af5f69c2a25bcbf6fd3d263aa0 428 Gene3D G3DSA:3.30.830.10 224 428 4.7E-26 T 29-03-2018 CSW12_RS08845 d00b24af5f69c2a25bcbf6fd3d263aa0 428 Pfam PF00675 Insulinase (Peptidase family M16) 64 150 5.8E-16 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CSW12_RS08845 d00b24af5f69c2a25bcbf6fd3d263aa0 428 SUPERFAMILY SSF63411 242 426 3.32E-20 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS08845 d00b24af5f69c2a25bcbf6fd3d263aa0 428 Pfam PF05193 Peptidase M16 inactive domain 181 361 6.3E-20 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CSW12_RS08845 d00b24af5f69c2a25bcbf6fd3d263aa0 428 SUPERFAMILY SSF63411 13 219 5.41E-42 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS08845 d00b24af5f69c2a25bcbf6fd3d263aa0 428 Gene3D G3DSA:3.30.830.10 2 223 1.9E-50 T 29-03-2018 CSW12_RS07630 039b0e4f1d0e767cccb5cb1e9af04c65 143 Pfam PF13162 Protein of unknown function (DUF3997) 28 132 3.2E-39 T 29-03-2018 IPR025059 Protein of unknown function DUF3997 CSW12_RS15975 a6ef26d5cebf175108a7c797f423224b 295 SUPERFAMILY SSF103481 197 289 8.63E-12 T 29-03-2018 CSW12_RS15975 a6ef26d5cebf175108a7c797f423224b 295 Pfam PF00892 EamA-like transporter family 8 139 7.1E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS15975 a6ef26d5cebf175108a7c797f423224b 295 Pfam PF00892 EamA-like transporter family 152 286 1.5E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS15975 a6ef26d5cebf175108a7c797f423224b 295 SUPERFAMILY SSF103481 38 143 6.02E-19 T 29-03-2018 CSW12_RS01805 7aae2cc9414173e1824e878beb8b9aca 243 Gene3D G3DSA:3.40.50.150 35 243 9.9E-31 T 29-03-2018 CSW12_RS01805 7aae2cc9414173e1824e878beb8b9aca 243 Pfam PF13489 Methyltransferase domain 45 210 1.4E-13 T 29-03-2018 CSW12_RS01805 7aae2cc9414173e1824e878beb8b9aca 243 SUPERFAMILY SSF53335 22 243 5.38E-34 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS10735 408e74d68d2a2baebe8c7772a3e8f177 106 Gene3D G3DSA:1.10.10.10 1 97 3.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10735 408e74d68d2a2baebe8c7772a3e8f177 106 Pfam PF03551 Transcriptional regulator PadR-like family 16 87 1.7E-23 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS10735 408e74d68d2a2baebe8c7772a3e8f177 106 SUPERFAMILY SSF46785 5 99 2.39E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29790 19bf8f98380173a2292bb9347a0ae98c 439 Pfam PF03432 Relaxase/Mobilisation nuclease domain 13 248 3.6E-36 T 29-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CSW12_RS13865 1ce5cc5be4a3b2b21364e039ffdcd0b6 85 Pfam PF13122 Protein of unknown function (DUF3977) 1 77 6.2E-51 T 29-03-2018 IPR025009 Protein of unknown function DUF3977 CSW12_RS30115 0608d6a4be4b688e759c3e0132f2eed8 93 Gene3D G3DSA:2.10.260.10 1 48 1.1E-16 T 29-03-2018 CSW12_RS30115 0608d6a4be4b688e759c3e0132f2eed8 93 SUPERFAMILY SSF89447 1 50 1.31E-14 T 29-03-2018 CSW12_RS30115 0608d6a4be4b688e759c3e0132f2eed8 93 SMART SM00966 8 51 6.0E-7 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS30115 0608d6a4be4b688e759c3e0132f2eed8 93 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 7.7E-8 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS30115 0608d6a4be4b688e759c3e0132f2eed8 93 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 48 7.7E-9 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS07985 a677d1b9bfb85063bc3213ff03d878e9 151 Gene3D G3DSA:2.30.110.10 1 150 4.1E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS07985 a677d1b9bfb85063bc3213ff03d878e9 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 10 94 1.0E-8 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CSW12_RS07985 a677d1b9bfb85063bc3213ff03d878e9 151 SUPERFAMILY SSF50475 6 96 3.49E-10 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS23925 bf78aa885660641d7af3332acb94637b 250 Pfam PF00005 ABC transporter 23 171 3.8E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS23925 bf78aa885660641d7af3332acb94637b 250 Gene3D G3DSA:3.40.50.300 1 237 2.2E-64 T 29-03-2018 CSW12_RS23925 bf78aa885660641d7af3332acb94637b 250 SMART SM00382 32 220 1.6E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS23925 bf78aa885660641d7af3332acb94637b 250 SUPERFAMILY SSF52540 4 224 5.97E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 123 1.5E-39 T 29-03-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 SUPERFAMILY SSF52540 77 166 1.33E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 SUPERFAMILY SSF52540 201 375 1.33E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Gene3D G3DSA:1.20.120.430 286 458 9.8E-31 T 29-03-2018 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Gene3D G3DSA:1.20.120.430 125 285 5.1E-31 T 29-03-2018 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 458 1.4E-130 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Pfam PF12631 MnmE helical domain 126 455 7.0E-61 T 29-03-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 SUPERFAMILY SSF116878 383 458 1.44E-51 T 29-03-2018 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 SUPERFAMILY SSF116878 124 224 1.44E-51 T 29-03-2018 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Gene3D G3DSA:3.30.1360.120 1 124 3.1E-44 T 29-03-2018 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Pfam PF01926 50S ribosome-binding GTPase 224 335 9.1E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 372 5.5E-28 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS27285 b71ff78990fb2392c7e124cd19750b2e 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 458 34.174 T 29-03-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CSW12_RS06835 0fc48c503a222d121cf009777f7f797f 170 Gene3D G3DSA:1.10.10.10 110 169 7.5E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06835 0fc48c503a222d121cf009777f7f797f 170 Gene3D G3DSA:2.60.120.10 2 109 5.6E-16 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS06835 0fc48c503a222d121cf009777f7f797f 170 SUPERFAMILY SSF46785 120 163 7.26E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06835 0fc48c503a222d121cf009777f7f797f 170 SUPERFAMILY SSF51206 3 113 1.96E-19 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS06835 0fc48c503a222d121cf009777f7f797f 170 Pfam PF00027 Cyclic nucleotide-binding domain 3 81 2.0E-10 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS21800 4daa6f8a6c54bbce2f9ba3126a5233ea 215 Gene3D G3DSA:2.40.33.20 3 215 5.5E-47 T 29-03-2018 CSW12_RS21800 4daa6f8a6c54bbce2f9ba3126a5233ea 215 SUPERFAMILY SSF50800 5 213 7.85E-67 T 29-03-2018 IPR011037 Pyruvate kinase-like, insert domain CSW12_RS21800 4daa6f8a6c54bbce2f9ba3126a5233ea 215 Pfam PF03475 3-alpha domain 171 213 2.6E-12 T 29-03-2018 IPR005163 3-alpha domain CSW12_RS21800 4daa6f8a6c54bbce2f9ba3126a5233ea 215 Pfam PF03473 MOSC domain 50 161 7.6E-21 T 29-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CSW12_RS02305 7a198c7563a3673b580d02fdaa2e62c3 308 Gene3D G3DSA:3.40.50.2300 39 143 9.8E-27 T 29-03-2018 CSW12_RS02305 7a198c7563a3673b580d02fdaa2e62c3 308 Gene3D G3DSA:3.40.50.2300 144 308 1.9E-43 T 29-03-2018 CSW12_RS02305 7a198c7563a3673b580d02fdaa2e62c3 308 Pfam PF13407 Periplasmic binding protein domain 41 292 2.5E-66 T 29-03-2018 IPR025997 Periplasmic binding protein CSW12_RS02305 7a198c7563a3673b580d02fdaa2e62c3 308 SUPERFAMILY SSF53822 33 307 3.6E-91 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS29920 33ce989db94b39d12f4a7791168466e7 193 SUPERFAMILY SSF53056 3 181 1.83E-42 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS29920 33ce989db94b39d12f4a7791168466e7 193 SMART SM00947 26 182 1.4E-36 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS29920 33ce989db94b39d12f4a7791168466e7 193 Gene3D G3DSA:3.40.1050.10 2 191 5.3E-37 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS29920 33ce989db94b39d12f4a7791168466e7 193 Pfam PF00484 Carbonic anhydrase 34 177 3.4E-18 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Pfam PF01645 Conserved region in glutamate synthase 791 1151 4.7E-100 T 29-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Pfam PF01493 GXGXG motif 1230 1399 4.4E-20 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 SUPERFAMILY SSF51395 448 1170 1.16E-161 T 29-03-2018 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Gene3D G3DSA:2.160.20.60 1201 1478 1.4E-54 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Gene3D G3DSA:3.20.20.70 767 1200 1.3E-103 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Gene3D G3DSA:3.20.20.70 432 766 1.4E-57 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 SUPERFAMILY SSF56235 24 398 3.38E-76 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Pfam PF00310 Glutamine amidotransferases class-II 24 392 5.3E-48 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Gene3D G3DSA:3.60.20.10 24 428 1.1E-66 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 Pfam PF04898 Glutamate synthase central domain 449 729 2.8E-70 T 29-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CSW12_RS01250 831010db37a6016c626f2e5b4970a0c7 1478 SUPERFAMILY SSF69336 1213 1474 6.28E-44 T 29-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CSW12_RS24040 6360b25d48e6c04a17451a9ea7e9ea66 243 SUPERFAMILY SSF109635 2 88 2.88E-15 T 29-03-2018 CSW12_RS24040 6360b25d48e6c04a17451a9ea7e9ea66 243 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 87 114 2.3E-10 T 29-03-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CSW12_RS24040 6360b25d48e6c04a17451a9ea7e9ea66 243 SUPERFAMILY SSF57716 89 118 3.85E-6 T 29-03-2018 CSW12_RS24040 6360b25d48e6c04a17451a9ea7e9ea66 243 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 5 160 5.4E-66 T 29-03-2018 IPR014240 Regulatory protein, YteA family CSW12_RS26735 13283da4a30eba26d368cb49fd0a85da 142 Pfam PF09671 Spore coat protein (Spore_GerQ) 56 130 6.9E-36 T 29-03-2018 IPR014099 Spore coat protein GerQ CSW12_RS26735 13283da4a30eba26d368cb49fd0a85da 142 PIRSF PIRSF038931 1 141 1.2E-43 T 29-03-2018 IPR014099 Spore coat protein GerQ CSW12_RS26735 13283da4a30eba26d368cb49fd0a85da 142 Gene3D G3DSA:3.40.640.10 23 139 2.1E-5 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS26735 13283da4a30eba26d368cb49fd0a85da 142 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 53 130 2.9E-35 T 29-03-2018 IPR014099 Spore coat protein GerQ CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 Gene3D G3DSA:3.20.20.70 1 215 6.3E-73 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 SUPERFAMILY SSF51569 1 212 1.15E-78 T 29-03-2018 CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 211 1.1E-55 T 29-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 29-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 Hamap MF_00494 Probable transaldolase [tal]. 1 214 48.355 T 29-03-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CSW12_RS02310 b97a2678aca606179a01c5fce862ea34 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 3.7E-102 T 29-03-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CSW12_RS05895 051ec7a03659f474389f09f08b7ff0d0 413 Gene3D G3DSA:3.40.190.10 46 157 1.3E-9 T 29-03-2018 CSW12_RS05895 051ec7a03659f474389f09f08b7ff0d0 413 Pfam PF12698 ABC-2 family transporter protein 19 383 1.6E-51 T 29-03-2018 CSW12_RS02475 926b2390a408ca079f502c369787aad7 385 SUPERFAMILY SSF56563 95 377 3.4E-21 T 29-03-2018 CSW12_RS02475 926b2390a408ca079f502c369787aad7 385 Gene3D G3DSA:3.30.2400.10 122 255 1.2E-9 T 29-03-2018 CSW12_RS02475 926b2390a408ca079f502c369787aad7 385 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 12 228 8.1E-11 T 29-03-2018 IPR024455 Phage capsid CSW12_RS02475 926b2390a408ca079f502c369787aad7 385 Pfam PF05065 Phage capsid family 103 371 4.7E-7 T 29-03-2018 IPR024455 Phage capsid CSW12_RS11255 36b0a5d731df0dad94f58f6e98eccb0f 119 Pfam PF12676 Protein of unknown function (DUF3796) 4 114 2.0E-33 T 29-03-2018 IPR024257 Protein of unknown function DUF3796 CSW12_RS05685 599035f3e273444f0ad4ce98842871c4 303 SUPERFAMILY SSF103481 38 140 9.16E-15 T 29-03-2018 CSW12_RS05685 599035f3e273444f0ad4ce98842871c4 303 SUPERFAMILY SSF103481 185 286 8.11E-13 T 29-03-2018 CSW12_RS05685 599035f3e273444f0ad4ce98842871c4 303 Pfam PF00892 EamA-like transporter family 13 136 3.1E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS05685 599035f3e273444f0ad4ce98842871c4 303 Pfam PF00892 EamA-like transporter family 149 282 3.4E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS04845 e3d0e777437fdfac310bf26c77b0eadd 121 SUPERFAMILY SSF54593 1 119 7.19E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS04845 e3d0e777437fdfac310bf26c77b0eadd 121 Gene3D G3DSA:3.10.180.10 1 121 1.0E-13 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS03110 0ab412abdf562f21c3ce4ef8a5ffa847 369 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 10 354 1.1E-44 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS03110 0ab412abdf562f21c3ce4ef8a5ffa847 369 Pfam PF03845 Spore germination protein 9 323 3.0E-80 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS07565 d178b4cbbeca8029063752f94e91075c 97 Pfam PF13065 Protein of unknown function (DUF3928) 1 95 1.3E-63 T 29-03-2018 IPR025170 Protein of unknown function DUF3928 CSW12_RS24735 e884be915d2f8368c9a80d2f45efdfa3 223 Gene3D G3DSA:1.10.3720.10 9 223 5.1E-36 T 29-03-2018 CSW12_RS24735 e884be915d2f8368c9a80d2f45efdfa3 223 SUPERFAMILY SSF161098 12 212 2.22E-44 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS24735 e884be915d2f8368c9a80d2f45efdfa3 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 221 1.6E-22 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS08480 88b9a2b59d0bfaf1854e4c847f637a04 26 Pfam PF08183 Stage V sporulation protein family 1 25 2.1E-17 T 29-03-2018 IPR012609 Sporulation stage V, protein M CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Pfam PF01391 Collagen triple helix repeat (20 copies) 635 693 5.2E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Pfam PF01391 Collagen triple helix repeat (20 copies) 593 648 5.8E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Pfam PF01391 Collagen triple helix repeat (20 copies) 66 116 1.2E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Pfam PF01391 Collagen triple helix repeat (20 copies) 20 77 9.9E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.60.120.40 695 837 7.3E-24 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 633 694 2.1E-16 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 574 632 4.4E-14 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 464 514 3.9E-13 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 515 573 6.7E-16 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 8 83 2.1E-13 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 180 248 7.1E-13 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 397 463 2.6E-11 T 29-03-2018 CSW12_RS11155 4e8544163c076721ebe7edf33a4bafdb 837 Gene3D G3DSA:2.160.20.50 84 162 1.1E-11 T 29-03-2018 CSW12_RS01560 466c28d1f2e8971d67086a4a5af4d9ca 458 Gene3D G3DSA:3.40.190.10 264 404 2.3E-19 T 29-03-2018 CSW12_RS01560 466c28d1f2e8971d67086a4a5af4d9ca 458 Gene3D G3DSA:3.40.190.10 49 240 5.7E-35 T 29-03-2018 CSW12_RS01560 466c28d1f2e8971d67086a4a5af4d9ca 458 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 159 176 - T 29-03-2018 IPR006061 Solute-binding family 1, conserved site GO:0006810 CSW12_RS01560 466c28d1f2e8971d67086a4a5af4d9ca 458 SUPERFAMILY SSF53850 50 445 1.59E-83 T 29-03-2018 CSW12_RS01560 466c28d1f2e8971d67086a4a5af4d9ca 458 Pfam PF13416 Bacterial extracellular solute-binding protein 67 383 9.1E-53 T 29-03-2018 CSW12_RS26325 aeb2b6948799cd30e4f3e28454757906 168 SUPERFAMILY SSF81573 71 129 2.09E-7 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CSW12_RS26325 aeb2b6948799cd30e4f3e28454757906 168 Gene3D G3DSA:1.20.5.620 70 130 2.5E-6 T 29-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CSW12_RS26325 aeb2b6948799cd30e4f3e28454757906 168 Hamap MF_01398 ATP synthase subunit b [atpF]. 9 146 13.273 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CSW12_RS26325 aeb2b6948799cd30e4f3e28454757906 168 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 21 164 3.8E-39 T 29-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CSW12_RS26325 aeb2b6948799cd30e4f3e28454757906 168 Pfam PF00430 ATP synthase B/B' CF(0) 14 145 1.4E-37 T 29-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CSW12_RS12640 0672d7b116ae67da7971b20116cf0bc9 127 Gene3D G3DSA:3.10.180.10 1 127 2.5E-20 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12640 0672d7b116ae67da7971b20116cf0bc9 127 Pfam PF12681 Glyoxalase-like domain 5 127 1.1E-44 T 29-03-2018 IPR025870 Glyoxalase-like domain CSW12_RS12640 0672d7b116ae67da7971b20116cf0bc9 127 SUPERFAMILY SSF54593 4 124 7.65E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12890 db25910cd58c330a5327b465eb4f8ab3 145 Pfam PF10710 Protein of unknown function (DUF2512) 3 135 8.0E-43 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 Gene3D G3DSA:3.40.50.720 1 175 1.2E-28 T 29-03-2018 CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 302 1.8E-71 T 29-03-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 177 300 1.7E-24 T 29-03-2018 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 SUPERFAMILY SSF51735 1 130 2.02E-15 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 Gene3D G3DSA:1.10.1040.10 177 309 2.1E-27 T 29-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 SUPERFAMILY SSF48179 177 301 2.24E-28 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS18455 cd9a7f5e1c30b6713a956d2d8b713d29 314 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 2.5E-37 T 29-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CSW12_RS22690 3727bd0645a48c3d54bf843cd4b59661 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 38.425 T 29-03-2018 IPR022877 Protein of unknown funcion UPF0173 CSW12_RS22690 3727bd0645a48c3d54bf843cd4b59661 227 SMART SM00849 7 193 5.1E-13 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS22690 3727bd0645a48c3d54bf843cd4b59661 227 Pfam PF13483 Beta-lactamase superfamily domain 2 193 9.4E-28 T 29-03-2018 CSW12_RS22690 3727bd0645a48c3d54bf843cd4b59661 227 SUPERFAMILY SSF56281 1 220 2.1E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS22690 3727bd0645a48c3d54bf843cd4b59661 227 Gene3D G3DSA:3.60.15.10 1 226 3.1E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS09645 6a3a253ecf171eca42ede0922eeee210 412 Pfam PF07690 Major Facilitator Superfamily 15 349 7.4E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS09645 6a3a253ecf171eca42ede0922eeee210 412 Gene3D G3DSA:1.20.1250.20 201 406 9.4E-20 T 29-03-2018 CSW12_RS09645 6a3a253ecf171eca42ede0922eeee210 412 SUPERFAMILY SSF103473 14 391 1.22E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS09645 6a3a253ecf171eca42ede0922eeee210 412 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS09645 6a3a253ecf171eca42ede0922eeee210 412 Gene3D G3DSA:1.20.1250.20 9 200 7.6E-29 T 29-03-2018 CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 Pfam PF13558 Putative exonuclease SbcCD, C subunit 924 985 2.0E-13 T 29-03-2018 CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 SUPERFAMILY SSF52540 920 1012 3.48E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 SUPERFAMILY SSF52540 26 191 3.48E-25 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 Gene3D G3DSA:3.40.50.300 688 1027 1.4E-16 T 29-03-2018 CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 Pfam PF13476 AAA domain 6 208 6.3E-31 T 29-03-2018 CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 Gene3D G3DSA:1.20.1330.10 330 665 2.3E-4 T 29-03-2018 CSW12_RS16235 0079e9375a5d4a46a451f8411defd98b 1029 Gene3D G3DSA:3.40.50.300 1 233 7.4E-28 T 29-03-2018 CSW12_RS26490 f6bc82bab31ad042bd840071e3823218 178 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 92 2.5E-34 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CSW12_RS26490 f6bc82bab31ad042bd840071e3823218 178 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 166 14.712 T 29-03-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 CSW12_RS26490 f6bc82bab31ad042bd840071e3823218 178 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 81 1.2E-10 T 29-03-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 CSW12_RS10910 3ec085e0b44ba9005afbad1b398c6728 138 Gene3D G3DSA:3.30.530.20 3 137 1.4E-26 T 29-03-2018 IPR023393 START-like domain CSW12_RS10910 3ec085e0b44ba9005afbad1b398c6728 138 SUPERFAMILY SSF55961 1 135 3.61E-35 T 29-03-2018 CSW12_RS10910 3ec085e0b44ba9005afbad1b398c6728 138 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 135 2.2E-22 T 29-03-2018 IPR019587 Polyketide cyclase/dehydrase CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 SMART SM00448 3 113 2.2E-45 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 223 4.2E-26 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 Pfam PF00072 Response regulator receiver domain 5 113 2.3E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 Gene3D G3DSA:3.40.50.2300 1 125 7.5E-38 T 29-03-2018 CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 SUPERFAMILY SSF52172 3 182 8.64E-42 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 Gene3D G3DSA:1.10.10.10 126 225 2.6E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09740 8e32ffa432677e0a3fa358af40e97e31 225 SMART SM00862 150 223 3.0E-27 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS14270 01cd54b948ec330e78441d47d2302e33 141 SUPERFAMILY SSF55729 6 138 1.93E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS14270 01cd54b948ec330e78441d47d2302e33 141 Gene3D G3DSA:3.40.630.30 1 141 3.9E-21 T 29-03-2018 CSW12_RS14270 01cd54b948ec330e78441d47d2302e33 141 Pfam PF00583 Acetyltransferase (GNAT) family 21 116 9.7E-15 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS21650 939422cc6232ada2da4d496b7e91cf45 255 Gene3D G3DSA:3.40.50.720 2 245 5.8E-45 T 29-03-2018 CSW12_RS21650 939422cc6232ada2da4d496b7e91cf45 255 SUPERFAMILY SSF69572 4 241 9.29E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS21650 939422cc6232ada2da4d496b7e91cf45 255 Pfam PF00899 ThiF family 6 158 1.5E-37 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 SUPERFAMILY SSF51735 2 250 6.96E-86 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.3E-37 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 Gene3D G3DSA:3.40.50.720 1 49 7.0E-13 T 29-03-2018 CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 Gene3D G3DSA:3.40.50.720 50 253 2.0E-55 T 29-03-2018 CSW12_RS07780 b266182c7dee07cfae6178251cb73b63 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 5.6E-62 T 29-03-2018 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 Gene3D G3DSA:3.30.200.20 1 93 8.6E-28 T 29-03-2018 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 Gene3D G3DSA:3.30.470.20 94 221 8.4E-49 T 29-03-2018 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 34.199 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 29-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 Pfam PF01259 SAICAR synthetase 7 232 4.0E-68 T 29-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 SUPERFAMILY SSF56104 1 236 1.31E-85 T 29-03-2018 CSW12_RS00035 8f204d8cd2feb42f94eb8982ba151bc9 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 236 3.5E-78 T 29-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CSW12_RS02705 342fa0f86711b7cf55eed8dde9265718 200 Gene3D G3DSA:1.20.120.80 14 199 7.9E-50 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02705 342fa0f86711b7cf55eed8dde9265718 200 Pfam PF00510 Cytochrome c oxidase subunit III 22 197 1.5E-14 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS02705 342fa0f86711b7cf55eed8dde9265718 200 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 11 199 1.4E-104 T 29-03-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 CSW12_RS02705 342fa0f86711b7cf55eed8dde9265718 200 SUPERFAMILY SSF81452 18 197 1.83E-53 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 230 3.5E-73 T 29-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 223 2.1E-60 T 29-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 SUPERFAMILY SSF53681 1 114 7.52E-38 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 SUPERFAMILY SSF53681 118 228 2.78E-33 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 Gene3D G3DSA:3.40.50.1860 1 118 1.5E-31 T 29-03-2018 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 192 202 - T 29-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 Gene3D G3DSA:3.40.50.1860 119 215 6.5E-26 T 29-03-2018 CSW12_RS16930 9060783ad28cbb24d79e3983642073f7 230 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 79 88 - T 29-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS05730 6825100c6ca51f2ce0cc842b9d5eb9b2 253 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 245 3.2E-81 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CSW12_RS05730 6825100c6ca51f2ce0cc842b9d5eb9b2 253 SUPERFAMILY SSF51366 3 248 8.36E-74 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS05730 6825100c6ca51f2ce0cc842b9d5eb9b2 253 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 251 32.645 T 29-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CSW12_RS05730 6825100c6ca51f2ce0cc842b9d5eb9b2 253 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 44 62 - T 29-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CSW12_RS05730 6825100c6ca51f2ce0cc842b9d5eb9b2 253 Gene3D G3DSA:3.20.20.70 4 252 7.2E-67 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS17260 010240d4ec015fcee6e82e40d3831987 337 SUPERFAMILY SSF69572 3 328 5.23E-87 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS17260 010240d4ec015fcee6e82e40d3831987 337 Gene3D G3DSA:3.40.50.720 21 269 1.2E-63 T 29-03-2018 CSW12_RS17260 010240d4ec015fcee6e82e40d3831987 337 Pfam PF00899 ThiF family 5 240 1.4E-62 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS16885 3f6ddbf21549b21238c3aadd5b679516 195 Pfam PF14005 YpjP-like protein 62 193 5.2E-61 T 29-03-2018 IPR025616 YpjP-like protein CSW12_RS08395 86eca9846bed9c2f6e7c8581611f17d7 569 Gene3D G3DSA:2.30.310.10 1 167 1.8E-53 T 29-03-2018 CSW12_RS08395 86eca9846bed9c2f6e7c8581611f17d7 569 Gene3D G3DSA:1.10.8.50 168 237 1.2E-16 T 29-03-2018 CSW12_RS08395 86eca9846bed9c2f6e7c8581611f17d7 569 Pfam PF05670 Domain of unknown function (DUF814) 456 538 5.0E-28 T 29-03-2018 IPR008532 Domain of unknown function DUF814 CSW12_RS08395 86eca9846bed9c2f6e7c8581611f17d7 569 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 1.8E-162 T 29-03-2018 CSW12_RS08395 86eca9846bed9c2f6e7c8581611f17d7 569 Gene3D G3DSA:3.40.970.40 242 290 1.5E-13 T 29-03-2018 CSW12_RS09515 a4abb7fc0c809db281bed8915484ad95 375 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 30 359 2.9E-89 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CSW12_RS09515 a4abb7fc0c809db281bed8915484ad95 375 SUPERFAMILY SSF51395 25 367 4.23E-111 T 29-03-2018 CSW12_RS09515 a4abb7fc0c809db281bed8915484ad95 375 Gene3D G3DSA:3.20.20.70 16 373 8.2E-116 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 Gene3D G3DSA:3.40.190.10 184 264 1.8E-13 T 29-03-2018 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 SUPERFAMILY SSF46785 1 109 5.29E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.2E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 Gene3D G3DSA:3.40.190.10 89 183 1.3E-14 T 29-03-2018 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 Pfam PF03466 LysR substrate binding domain 88 286 1.4E-36 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 Gene3D G3DSA:1.10.10.10 1 81 1.5E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.3E-18 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS15915 ff34c7e35956ce675ab345d30f247a19 288 SUPERFAMILY SSF53850 85 286 2.81E-34 T 29-03-2018 CSW12_RS08455 9716f3668eb615a2d6fe1030558f199f 250 Pfam PF13672 Protein phosphatase 2C 12 203 1.3E-22 T 29-03-2018 CSW12_RS08455 9716f3668eb615a2d6fe1030558f199f 250 SMART SM00331 7 242 7.7E-45 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS08455 9716f3668eb615a2d6fe1030558f199f 250 SUPERFAMILY SSF81606 2 241 5.49E-65 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS08455 9716f3668eb615a2d6fe1030558f199f 250 SMART SM00332 1 240 2.3E-23 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS08455 9716f3668eb615a2d6fe1030558f199f 250 Gene3D G3DSA:3.60.40.10 1 242 2.2E-43 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS21540 af4ce909284269f40d6629b9de522f23 426 Gene3D G3DSA:3.20.20.70 14 201 2.3E-7 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS21540 af4ce909284269f40d6629b9de522f23 426 ProSitePatterns PS01276 Peptidase family U32 signature. 177 195 - T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CSW12_RS21540 af4ce909284269f40d6629b9de522f23 426 Pfam PF16325 Peptidase family U32 C-terminal domain 340 421 1.5E-26 T 29-03-2018 IPR032525 Peptidase family U32, C-terminal CSW12_RS21540 af4ce909284269f40d6629b9de522f23 426 Pfam PF01136 Peptidase family U32 91 325 3.8E-84 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CSW12_RS30600 eb2648270c2f47d538cf3d6192d7f4d6 364 Gene3D G3DSA:2.60.200.20 117 257 2.9E-4 T 29-03-2018 CSW12_RS14415 a25a934a6dc571ef7c44d7b8e0364e5a 341 SUPERFAMILY SSF56601 5 330 1.88E-73 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS14415 a25a934a6dc571ef7c44d7b8e0364e5a 341 Pfam PF00144 Beta-lactamase 11 331 3.3E-41 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS14415 a25a934a6dc571ef7c44d7b8e0364e5a 341 Gene3D G3DSA:3.40.710.10 2 341 5.0E-67 T 29-03-2018 CSW12_RS28415 5c916eeeaa733d4abc6397f57e5ba505 530 Gene3D G3DSA:3.10.105.10 294 500 9.9E-47 T 29-03-2018 CSW12_RS28415 5c916eeeaa733d4abc6397f57e5ba505 530 Gene3D G3DSA:3.90.76.10 66 159 5.5E-25 T 29-03-2018 CSW12_RS28415 5c916eeeaa733d4abc6397f57e5ba505 530 Gene3D G3DSA:3.40.190.10 160 293 7.5E-37 T 29-03-2018 CSW12_RS28415 5c916eeeaa733d4abc6397f57e5ba505 530 PIRSF PIRSF002741 1 530 4.2E-99 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS28415 5c916eeeaa733d4abc6397f57e5ba505 530 SUPERFAMILY SSF53850 35 525 7.78E-112 T 29-03-2018 CSW12_RS28415 5c916eeeaa733d4abc6397f57e5ba505 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 449 2.7E-68 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 SUPERFAMILY SSF48498 89 187 2.17E-10 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 Gene3D G3DSA:1.10.357.10 61 187 1.8E-10 T 29-03-2018 CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 SUPERFAMILY SSF46689 5 80 8.98E-16 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 2.3E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 Gene3D G3DSA:1.10.10.60 4 60 2.1E-13 T 29-03-2018 CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS15320 47361208565db8c3899a321bd3b7085a 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.3E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS24490 93f20a6fb71147708aad71186bbc7211 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 2 78 4.0E-38 T 29-03-2018 CSW12_RS24490 93f20a6fb71147708aad71186bbc7211 79 Hamap MF_01542 UPF0349 protein . 2 78 29.928 T 29-03-2018 IPR022916 Protein of unknown function UPF0349 CSW12_RS24490 93f20a6fb71147708aad71186bbc7211 79 Pfam PF07293 Protein of unknown function (DUF1450) 2 76 9.0E-35 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 CSW12_RS18030 f5ec032561e337f68445e33ca61160dc 202 SUPERFAMILY SSF55811 3 154 4.74E-22 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS18030 f5ec032561e337f68445e33ca61160dc 202 Pfam PF00293 NUDIX domain 30 144 1.5E-7 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS18030 f5ec032561e337f68445e33ca61160dc 202 Gene3D G3DSA:3.90.79.10 16 171 3.4E-14 T 29-03-2018 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 29-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 SUPERFAMILY SSF47005 113 158 8.11E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 Gene3D G3DSA:4.10.320.10 110 192 2.1E-16 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 209 432 7.8E-79 T 29-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 Pfam PF02817 e3 binding domain 120 154 2.1E-12 T 29-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 Pfam PF00364 Biotin-requiring enzyme 5 77 1.7E-22 T 29-03-2018 IPR000089 Biotin/lipoyl attachment CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 Gene3D G3DSA:2.40.50.100 6 79 4.0E-18 T 29-03-2018 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 SUPERFAMILY SSF51230 3 96 1.16E-26 T 29-03-2018 IPR011053 Single hybrid motif CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 Gene3D G3DSA:3.30.559.10 193 438 1.6E-83 T 29-03-2018 CSW12_RS20370 5fa23fdf03441165111e36fdb33f629f 439 SUPERFAMILY SSF52777 210 431 1.78E-80 T 29-03-2018 CSW12_RS00735 3d1afa35d2b20194d3aaf07a47b866eb 456 Pfam PF01565 FAD binding domain 35 163 1.2E-26 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS00735 3d1afa35d2b20194d3aaf07a47b866eb 456 Pfam PF08031 Berberine and berberine like 397 440 6.7E-21 T 29-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CSW12_RS00735 3d1afa35d2b20194d3aaf07a47b866eb 456 Gene3D G3DSA:3.30.43.10 8 86 3.0E-15 T 29-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CSW12_RS00735 3d1afa35d2b20194d3aaf07a47b866eb 456 SUPERFAMILY SSF56176 6 204 1.31E-49 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS00735 3d1afa35d2b20194d3aaf07a47b866eb 456 Gene3D G3DSA:3.30.465.10 87 230 4.5E-35 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS06895 2199db3ca00f623493a9d4f1a49f1758 176 Pfam PF00589 Phage integrase family 11 173 1.7E-22 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS06895 2199db3ca00f623493a9d4f1a49f1758 176 Gene3D G3DSA:1.10.443.10 7 176 1.4E-28 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS06895 2199db3ca00f623493a9d4f1a49f1758 176 SUPERFAMILY SSF56349 8 175 7.95E-34 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS17055 716bf5e903d7bf9ff2f18c3f7ff9e47a 503 Pfam PF03413 Peptidase propeptide and YPEB domain 122 192 1.5E-8 T 29-03-2018 IPR025711 PepSY domain CSW12_RS17055 716bf5e903d7bf9ff2f18c3f7ff9e47a 503 Pfam PF02128 Fungalysin metallopeptidase (M36) 334 500 4.7E-13 T 29-03-2018 IPR001842 Peptidase M36, fungalysin GO:0004222|GO:0005615|GO:0008270 CSW12_RS17055 716bf5e903d7bf9ff2f18c3f7ff9e47a 503 Gene3D G3DSA:1.10.390.10 362 503 1.7E-23 T 29-03-2018 CSW12_RS17055 716bf5e903d7bf9ff2f18c3f7ff9e47a 503 SUPERFAMILY SSF55486 243 500 3.48E-40 T 29-03-2018 CSW12_RS17055 716bf5e903d7bf9ff2f18c3f7ff9e47a 503 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 75 104 1.3E-6 T 29-03-2018 IPR011096 FTP domain CSW12_RS17055 716bf5e903d7bf9ff2f18c3f7ff9e47a 503 Gene3D G3DSA:3.10.170.10 195 357 1.1E-10 T 29-03-2018 CSW12_RS13825 131be2b86bb4ba06340902e4041aa0e8 133 Gene3D G3DSA:1.10.10.10 1 132 4.8E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13825 131be2b86bb4ba06340902e4041aa0e8 133 SUPERFAMILY SSF46785 2 129 2.84E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13825 131be2b86bb4ba06340902e4041aa0e8 133 Pfam PF02082 Transcriptional regulator 1 83 7.2E-29 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS13825 131be2b86bb4ba06340902e4041aa0e8 133 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 127 2.1E-38 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS17170 c733b2da04e94e333a76b6acfcba16aa 533 SUPERFAMILY SSF53474 57 265 1.55E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS17170 c733b2da04e94e333a76b6acfcba16aa 533 Gene3D G3DSA:3.40.50.1820 188 438 1.7E-10 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS17170 c733b2da04e94e333a76b6acfcba16aa 533 Gene3D G3DSA:3.40.50.1820 52 187 2.1E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 29-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 228 3.3E-48 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 SMART SM00934 4 229 2.5E-92 T 29-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 39.839 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 229 2.9E-64 T 29-03-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 Gene3D G3DSA:3.20.20.70 1 233 7.2E-65 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS08340 60e919374ee73c587704eadc7a98cebf 238 SUPERFAMILY SSF51366 4 233 4.19E-73 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 Pfam PF00574 Clp protease 13 192 4.6E-87 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 191 5.8E-107 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.238 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 29-03-2018 IPR018215 ClpP, Ser active site CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 29-03-2018 IPR033135 ClpP, histidine active site CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 Gene3D G3DSA:3.90.226.10 2 193 6.1E-47 T 29-03-2018 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.6E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 3.6E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 3.6E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 3.6E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 3.6E-54 T 29-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CSW12_RS25445 b81d37ad1baf6afe8a68d4582d88540c 193 SUPERFAMILY SSF52096 10 192 7.02E-74 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS00310 abb67395f3f07e26cf1f5a026317fb03 86 Pfam PF05135 Phage gp6-like head-tail connector protein 5 61 2.3E-6 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein CSW12_RS11670 5de8f6ae8288b37c805bbc3d1bb793c1 306 Pfam PF04072 Leucine carboxyl methyltransferase 13 207 3.3E-49 T 29-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CSW12_RS11670 5de8f6ae8288b37c805bbc3d1bb793c1 306 SUPERFAMILY SSF53335 9 305 2.75E-64 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS11670 5de8f6ae8288b37c805bbc3d1bb793c1 306 Gene3D G3DSA:3.40.50.150 5 296 3.6E-36 T 29-03-2018 CSW12_RS11670 5de8f6ae8288b37c805bbc3d1bb793c1 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 286 6.4E-45 T 29-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 Pfam PF02080 TrkA-C domain 261 330 1.7E-14 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 SUPERFAMILY SSF116726 255 330 7.85E-20 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 Pfam PF07885 Ion channel 16 90 3.0E-15 T 29-03-2018 IPR013099 Potassium channel domain CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 Gene3D G3DSA:3.30.70.1450 248 331 1.6E-16 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 Gene3D G3DSA:1.10.287.70 5 97 1.2E-16 T 29-03-2018 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 SUPERFAMILY SSF51735 110 248 3.2E-36 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 Pfam PF02254 TrkA-N domain 114 226 9.8E-33 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 Gene3D G3DSA:3.40.50.720 103 225 2.1E-28 T 29-03-2018 CSW12_RS26755 dd54e323a962c5eb914543061a69e90f 334 SUPERFAMILY SSF81324 7 132 1.57E-27 T 29-03-2018 CSW12_RS30830 cf6c84a339e95544c8939106eef8a2bd 64 Gene3D G3DSA:1.10.260.40 2 63 4.0E-18 T 29-03-2018 CSW12_RS30830 cf6c84a339e95544c8939106eef8a2bd 64 Pfam PF01381 Helix-turn-helix 4 59 2.1E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30830 cf6c84a339e95544c8939106eef8a2bd 64 SUPERFAMILY SSF47413 2 60 7.78E-17 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS30830 cf6c84a339e95544c8939106eef8a2bd 64 SMART SM00530 3 59 1.5E-16 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 416 1.8E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 SMART SM00387 313 417 2.6E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 SUPERFAMILY SSF47384 192 270 5.49E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 Gene3D G3DSA:3.30.565.10 268 417 5.1E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.9E-13 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 Pfam PF07694 5TMR of 5TMR-LYT 26 186 3.4E-6 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 270 1.4E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 Gene3D G3DSA:1.10.287.130 193 267 1.4E-12 T 29-03-2018 CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 SUPERFAMILY SSF55874 263 417 6.94E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS10120 1c72d17589b518ae64ec3b3715492fbd 417 SMART SM00388 206 272 1.3E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS21445 eb25d2615fd49a686252ee12f6f2b6d2 152 SUPERFAMILY SSF55729 19 130 4.88E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS21445 eb25d2615fd49a686252ee12f6f2b6d2 152 Gene3D G3DSA:3.40.630.30 10 145 1.1E-15 T 29-03-2018 CSW12_RS21445 eb25d2615fd49a686252ee12f6f2b6d2 152 Pfam PF13508 Acetyltransferase (GNAT) domain 57 128 6.3E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS04370 0a718e731bbb1f5b266fc402aecfbfb1 46 Pfam PF11121 Protein of unknown function (DUF2639) 2 39 1.1E-20 T 29-03-2018 IPR022580 Protein of unknown function DUF2639 CSW12_RS04370 0a718e731bbb1f5b266fc402aecfbfb1 46 ProDom PD049467 YFLJ 1 43 3.0E-17 T 29-03-2018 IPR022580 Protein of unknown function DUF2639 CSW12_RS08930 5cd7a6916a4102875504d60db753944c 180 Pfam PF10628 Outer spore coat protein E (CotE) 4 175 1.5E-65 T 29-03-2018 IPR018901 Spore coat protein CotE CSW12_RS11785 310f0d1d2fb1c1debe8945982879c3c2 331 Pfam PF04892 VanZ like family 47 174 1.5E-11 T 29-03-2018 IPR006976 VanZ-like CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SMART SM00345 14 73 4.3E-21 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SUPERFAMILY SSF46785 5 84 6.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 9.2E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SMART SM00866 95 233 1.2E-24 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Gene3D G3DSA:3.40.1410.10 74 241 6.8E-30 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Gene3D G3DSA:1.10.10.10 2 73 1.4E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 SUPERFAMILY SSF64288 63 239 2.04E-38 T 29-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 Pfam PF07702 UTRA domain 96 232 1.4E-31 T 29-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS08815 a0eaa0c1c9d2db09d3c8b9d5fe0878bb 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.2E-9 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS13045 1a721871b5fe08f0c2cc0d046fb522d7 229 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 1 182 2.9E-30 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CSW12_RS13045 1a721871b5fe08f0c2cc0d046fb522d7 229 SUPERFAMILY SSF102645 2 222 2.22E-43 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CSW12_RS13045 1a721871b5fe08f0c2cc0d046fb522d7 229 Gene3D G3DSA:3.40.50.10300 1 227 3.2E-45 T 29-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 71.632 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 Gene3D G3DSA:1.10.10.10 3 66 1.5E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 SUPERFAMILY SSF55252 80 149 4.32E-22 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 SUPERFAMILY SSF46785 5 78 6.81E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 Gene3D G3DSA:3.30.1360.40 74 146 5.1E-28 T 29-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 1.0E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 1.0E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 1.0E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 1.0E-28 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 Pfam PF02863 Arginine repressor, C-terminal domain 82 145 2.8E-25 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 7.2E-31 T 29-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 1.8E-52 T 29-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CSW12_RS20460 23ece76d112e7fb5e0ff539bfedfad21 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 5.0E-31 T 29-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CSW12_RS25195 a8996f9cbc8ef474e4194147f71dd237 79 Pfam PF13135 Protein of unknown function (DUF3947) 2 79 3.6E-30 T 29-03-2018 IPR025039 Protein of unknown function DUF3947 CSW12_RS18035 0499c3a78b67e92595eeb6f4444f336c 113 Pfam PF13630 SdpI/YhfL protein family 32 98 1.7E-15 T 29-03-2018 IPR025962 SdpI/YhfL protein family CSW12_RS21120 b3284ed905f1ca8e66b4939f3b240e06 117 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 65 76 - T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CSW12_RS21120 b3284ed905f1ca8e66b4939f3b240e06 117 Gene3D G3DSA:1.10.3830.10 2 114 1.2E-42 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CSW12_RS21120 b3284ed905f1ca8e66b4939f3b240e06 117 Pfam PF01219 Prokaryotic diacylglycerol kinase 11 112 2.2E-37 T 29-03-2018 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 CSW12_RS28075 30e961bb7e73ce9e21cae044775b83fa 60 Gene3D G3DSA:3.30.1390.20 5 59 7.8E-25 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CSW12_RS28075 30e961bb7e73ce9e21cae044775b83fa 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.91 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28075 30e961bb7e73ce9e21cae044775b83fa 60 SUPERFAMILY SSF55129 3 59 9.16E-21 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CSW12_RS28075 30e961bb7e73ce9e21cae044775b83fa 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 4.0E-20 T 29-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CSW12_RS28075 30e961bb7e73ce9e21cae044775b83fa 60 PIRSF PIRSF002211 1 60 5.0E-29 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28075 30e961bb7e73ce9e21cae044775b83fa 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 1.3E-26 T 29-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS14250 9e3756706fa4a2fcc1ddb6541489edcd 320 Gene3D G3DSA:3.60.15.10 31 317 1.0E-49 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS14250 9e3756706fa4a2fcc1ddb6541489edcd 320 Pfam PF12706 Beta-lactamase superfamily domain 72 267 1.5E-41 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS14250 9e3756706fa4a2fcc1ddb6541489edcd 320 PIRSF PIRSF038896 2 309 7.0E-93 T 29-03-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 CSW12_RS14250 9e3756706fa4a2fcc1ddb6541489edcd 320 SUPERFAMILY SSF56281 55 131 1.6E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS14250 9e3756706fa4a2fcc1ddb6541489edcd 320 SUPERFAMILY SSF56281 158 306 1.6E-37 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS17925 d194a4f40bd143645804fab724b2a7a3 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 64 1.7E-21 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS17925 d194a4f40bd143645804fab724b2a7a3 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS17925 d194a4f40bd143645804fab724b2a7a3 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS20775 58d6570d119ff0ea2827d05bb512a3e8 232 Gene3D G3DSA:2.60.120.620 45 231 2.2E-41 T 29-03-2018 CSW12_RS20775 58d6570d119ff0ea2827d05bb512a3e8 232 SMART SM00702 55 227 3.6E-45 T 29-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CSW12_RS20775 58d6570d119ff0ea2827d05bb512a3e8 232 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 130 227 1.7E-17 T 29-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CSW12_RS17145 f86938bf7dd013bd935d0c5c0b319e98 215 SUPERFAMILY SSF109604 4 213 1.28E-75 T 29-03-2018 CSW12_RS17145 f86938bf7dd013bd935d0c5c0b319e98 215 SMART SM00471 22 136 1.5E-8 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS17145 f86938bf7dd013bd935d0c5c0b319e98 215 Gene3D G3DSA:1.10.3210.10 1 214 9.0E-27 T 29-03-2018 CSW12_RS17145 f86938bf7dd013bd935d0c5c0b319e98 215 Pfam PF01966 HD domain 28 126 2.9E-9 T 29-03-2018 IPR006674 HD domain CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 Gene3D G3DSA:1.10.1660.10 61 141 1.1E-7 T 29-03-2018 CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 1.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 1.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 1.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 SMART SM00422 5 74 1.6E-27 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 SUPERFAMILY SSF46955 6 117 1.83E-27 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 Gene3D G3DSA:1.10.1660.10 4 60 9.7E-23 T 29-03-2018 CSW12_RS25540 06b1f4af48ee15e642b23896010fc16e 254 Pfam PF13411 MerR HTH family regulatory protein 6 71 8.8E-18 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS13970 1d6bba336d2b5e28d4dc1571e9310ceb 178 Gene3D G3DSA:3.30.70.1260 98 175 1.8E-14 T 29-03-2018 CSW12_RS13970 1d6bba336d2b5e28d4dc1571e9310ceb 178 PIRSF PIRSF008502 1 178 1.1E-62 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 CSW12_RS13970 1d6bba336d2b5e28d4dc1571e9310ceb 178 Gene3D G3DSA:3.30.70.1280 2 86 1.8E-32 T 29-03-2018 CSW12_RS13970 1d6bba336d2b5e28d4dc1571e9310ceb 178 SUPERFAMILY SSF160379 1 175 1.7E-50 T 29-03-2018 CSW12_RS13970 1d6bba336d2b5e28d4dc1571e9310ceb 178 Pfam PF08002 Protein of unknown function (DUF1697) 1 137 2.5E-42 T 29-03-2018 IPR012545 Protein of unknown function DUF1697 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 SUPERFAMILY SSF89260 855 964 3.27E-30 T 29-03-2018 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 Pfam PF00801 PKD domain 793 840 2.8E-11 T 29-03-2018 IPR000601 PKD domain CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 SUPERFAMILY SSF49299 733 850 2.22E-18 T 29-03-2018 IPR000601 PKD domain CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 463 479 5.0E-30 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 526 541 5.0E-30 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 446 460 5.0E-30 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 500 518 5.0E-30 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 PRINTS PR00931 Microbial collagenase metalloprotease (M9) signature 160 178 5.0E-30 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 886 951 1.4E-5 T 29-03-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 Gene3D G3DSA:2.60.40.10 761 850 1.8E-20 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 Gene3D G3DSA:2.60.120.380 851 965 6.8E-20 T 29-03-2018 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 Pfam PF01752 Collagenase 310 632 7.1E-82 T 29-03-2018 IPR002169 Peptidase M9A/M9B, collagenase, bacterial GO:0004252|GO:0005576|GO:0006508|GO:0008270 CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 Pfam PF08453 Peptidase family M9 N-terminal 94 275 3.2E-52 T 29-03-2018 IPR013661 Peptidase M9, collagenase, N-terminal domain CSW12_RS01485 19d11a24a5e7206a3e2e8608f5af4efc 965 SMART SM00089 771 853 1.4E-17 T 29-03-2018 IPR022409 PKD/Chitinase domain CSW12_RS10790 f0ab5f882947aa830e59efdbba9ed753 240 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 18 233 5.8E-97 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CSW12_RS10790 f0ab5f882947aa830e59efdbba9ed753 240 SUPERFAMILY SSF88946 20 100 5.49E-17 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS10790 f0ab5f882947aa830e59efdbba9ed753 240 Pfam PF04542 Sigma-70 region 2 32 101 1.3E-8 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS10790 f0ab5f882947aa830e59efdbba9ed753 240 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 13 235 28.278 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CSW12_RS10790 f0ab5f882947aa830e59efdbba9ed753 240 Gene3D G3DSA:1.10.1740.10 16 99 2.6E-12 T 29-03-2018 CSW12_RS10790 f0ab5f882947aa830e59efdbba9ed753 240 PIRSF PIRSF038953 6 240 2.3E-59 T 29-03-2018 IPR014244 RNA polymerase sigma-I type CSW12_RS11080 0856970d74797b75ae2465d3193d3d0f 407 Pfam PF08421 Putative zinc binding domain 6 67 2.5E-22 T 29-03-2018 IPR013630 Methyltransferase putative zinc binding domain CSW12_RS11080 0856970d74797b75ae2465d3193d3d0f 407 Pfam PF13489 Methyltransferase domain 96 236 1.7E-14 T 29-03-2018 CSW12_RS11080 0856970d74797b75ae2465d3193d3d0f 407 SUPERFAMILY SSF53335 69 250 2.19E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS11080 0856970d74797b75ae2465d3193d3d0f 407 Pfam PF08484 C-methyltransferase C-terminal domain 243 400 2.4E-61 T 29-03-2018 IPR013691 C-methyltransferase CSW12_RS11080 0856970d74797b75ae2465d3193d3d0f 407 Gene3D G3DSA:3.40.50.150 57 254 3.2E-25 T 29-03-2018 CSW12_RS11805 57d75e19e51b39e2fb030324956f266c 469 Pfam PF00324 Amino acid permease 17 457 1.3E-117 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS11805 57d75e19e51b39e2fb030324956f266c 469 PIRSF PIRSF006060 1 468 1.7E-77 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS11805 57d75e19e51b39e2fb030324956f266c 469 ProSitePatterns PS00218 Amino acid permeases signature. 42 73 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS06805 28ab320245c79a7857c9476f22d8f441 258 SUPERFAMILY SSF53335 4 195 8.44E-38 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS06805 28ab320245c79a7857c9476f22d8f441 258 Gene3D G3DSA:3.40.50.150 3 241 9.3E-36 T 29-03-2018 CSW12_RS06805 28ab320245c79a7857c9476f22d8f441 258 Pfam PF08241 Methyltransferase domain 40 134 1.1E-26 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 SUPERFAMILY SSF56024 203 362 5.61E-38 T 29-03-2018 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 Gene3D G3DSA:3.30.870.10 9 192 1.5E-30 T 29-03-2018 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 Gene3D G3DSA:3.30.870.10 193 354 1.9E-28 T 29-03-2018 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 21 374 5.4E-95 T 29-03-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 SMART SM00155 290 317 1.4E-4 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 SMART SM00155 121 148 0.042 T 29-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 PIRSF PIRSF000850 206 268 5.9E-5 T 29-03-2018 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 PIRSF PIRSF000850 280 347 13.0 T 29-03-2018 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 PIRSF PIRSF000850 14 109 0.2 T 29-03-2018 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 Pfam PF13091 PLD-like domain 220 339 9.6E-29 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 Pfam PF13091 PLD-like domain 39 181 1.5E-12 T 29-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CSW12_RS17645 36ce3907c890e60cddd6b9fddb111c15 377 SUPERFAMILY SSF56024 24 196 1.07E-40 T 29-03-2018 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 SUPERFAMILY SSF46689 4 78 2.96E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 3.2E-16 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 6.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 6.5E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 Gene3D G3DSA:1.10.10.60 4 58 6.9E-15 T 29-03-2018 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 Gene3D G3DSA:1.10.357.10 59 185 4.2E-17 T 29-03-2018 CSW12_RS04715 9992f00c18639964d988682c962100ad 190 SUPERFAMILY SSF48498 76 189 4.14E-14 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS04715 9992f00c18639964d988682c962100ad 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS25470 f073d31fbfc428d62a95c65a41084b58 293 Gene3D G3DSA:3.40.50.300 1 38 0.27 T 29-03-2018 CSW12_RS25470 f073d31fbfc428d62a95c65a41084b58 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 7 289 42.61 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CSW12_RS25470 f073d31fbfc428d62a95c65a41084b58 293 Pfam PF03668 P-loop ATPase protein family 7 290 1.1E-124 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CSW12_RS25470 f073d31fbfc428d62a95c65a41084b58 293 PIRSF PIRSF005052 7 292 1.1E-109 T 29-03-2018 IPR005337 RapZ-like family GO:0005524 CSW12_RS25470 f073d31fbfc428d62a95c65a41084b58 293 Gene3D G3DSA:3.40.50.300 39 175 8.0E-5 T 29-03-2018 CSW12_RS25470 f073d31fbfc428d62a95c65a41084b58 293 SUPERFAMILY SSF52540 4 162 1.56E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS15245 3da7bd45acad3b24f082abdfb9557252 199 Gene3D G3DSA:2.60.40.10 28 188 4.1E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS15245 3da7bd45acad3b24f082abdfb9557252 199 Pfam PF12389 Camelysin metallo-endopeptidase 3 198 9.5E-88 T 29-03-2018 IPR022121 Peptidase M73, camelysin CSW12_RS15245 3da7bd45acad3b24f082abdfb9557252 199 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 13 44 6.9E-13 T 29-03-2018 IPR023833 Signal peptide, camelysin CSW12_RS17400 6a583412abe5a7928f261189a83a2762 141 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 2 125 1.0E-48 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS17400 6a583412abe5a7928f261189a83a2762 141 PIRSF PIRSF021377 1 140 1.5E-53 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS17400 6a583412abe5a7928f261189a83a2762 141 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 30 116 1.4E-26 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS00545 99bb353fb0eea495157c152a1714a9de 201 SUPERFAMILY SSF53335 4 142 1.48E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS00545 99bb353fb0eea495157c152a1714a9de 201 Gene3D G3DSA:3.40.50.150 19 175 3.4E-12 T 29-03-2018 CSW12_RS00545 99bb353fb0eea495157c152a1714a9de 201 Pfam PF13679 Methyltransferase domain 46 103 1.2E-7 T 29-03-2018 IPR025714 Methyltransferase domain CSW12_RS18700 4f7c7d48bf2d98ef4ef13b3b9763c996 403 Pfam PF07690 Major Facilitator Superfamily 23 361 1.8E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS18700 4f7c7d48bf2d98ef4ef13b3b9763c996 403 Gene3D G3DSA:1.20.1250.20 1 205 9.7E-23 T 29-03-2018 CSW12_RS18700 4f7c7d48bf2d98ef4ef13b3b9763c996 403 SUPERFAMILY SSF103473 11 395 1.96E-56 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS18700 4f7c7d48bf2d98ef4ef13b3b9763c996 403 Gene3D G3DSA:1.20.1250.20 206 401 1.7E-23 T 29-03-2018 CSW12_RS20320 411b75095020f5c0892c1a6ff559860e 322 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 8.8E-54 T 29-03-2018 IPR021062 Putative aromatic acid exporter, C-terminal CSW12_RS20320 411b75095020f5c0892c1a6ff559860e 322 Pfam PF06081 Aromatic acid exporter family member 1 2 142 1.5E-51 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CSW12_RS14135 66a8318b00098807ecdd28befab7dcbc 220 Gene3D G3DSA:1.10.510.10 33 184 1.4E-8 T 29-03-2018 CSW12_RS14135 66a8318b00098807ecdd28befab7dcbc 220 SUPERFAMILY SSF56112 38 188 1.4E-12 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS19360 9c407948cb19ff47a8ab3c384efa0dca 135 PIRSF PIRSF002889 8 134 3.8E-19 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CSW12_RS19360 9c407948cb19ff47a8ab3c384efa0dca 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 9 127 6.4E-21 T 29-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CSW12_RS19360 9c407948cb19ff47a8ab3c384efa0dca 135 Pfam PF00460 Flagella basal body rod protein 20 35 5.6E-7 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CSW12_RS19360 9c407948cb19ff47a8ab3c384efa0dca 135 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 29-03-2018 IPR019776 Flagellar basal body rod protein, conserved site CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.7E-12 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 6.8E-20 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 56 187 1.2E-55 T 29-03-2018 IPR032551 HTH-type transcriptional repressor, C-terminal CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 SUPERFAMILY SSF46689 4 67 1.6E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 29-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 Gene3D G3DSA:1.10.10.60 1 57 3.1E-20 T 29-03-2018 CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 SUPERFAMILY SSF48498 78 185 8.34E-9 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS12935 d03aa7f0997be48c836d364b480f43b7 188 Gene3D G3DSA:1.10.357.10 58 188 3.3E-12 T 29-03-2018 CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Pfam PF00156 Phosphoribosyl transferase domain 268 381 5.5E-8 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 SUPERFAMILY SSF56235 12 238 2.14E-71 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 456 1.3E-168 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Gene3D G3DSA:3.40.50.2020 239 437 1.2E-34 T 29-03-2018 CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 SUPERFAMILY SSF53271 246 463 4.06E-77 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Gene3D G3DSA:3.60.20.10 12 238 6.1E-59 T 29-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 455 47.602 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 Pfam PF13537 Glutamine amidotransferase domain 93 208 8.0E-22 T 29-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CSW12_RS00055 42c07f71ae1cab15dc7c4fe1b8216b8b 471 PIRSF PIRSF000485 8 471 1.9E-185 T 29-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CSW12_RS13305 1f3feac6d445678a30268496cb5d5851 256 SUPERFAMILY SSF55729 90 254 1.48E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13305 1f3feac6d445678a30268496cb5d5851 256 Pfam PF12746 GNAT acetyltransferase 15 251 8.3E-84 T 29-03-2018 IPR027365 GNAT acetyltransferase YdfB-like CSW12_RS13305 1f3feac6d445678a30268496cb5d5851 256 Gene3D G3DSA:3.40.630.30 111 243 4.2E-18 T 29-03-2018 CSW12_RS28330 6ea08ce6df5809639e2af450e07c7674 270 Gene3D G3DSA:3.40.190.10 131 270 1.2E-50 T 29-03-2018 CSW12_RS28330 6ea08ce6df5809639e2af450e07c7674 270 PIRSF PIRSF002854 1 270 1.0E-91 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS28330 6ea08ce6df5809639e2af450e07c7674 270 Pfam PF03180 NLPA lipoprotein 35 270 2.3E-87 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS28330 6ea08ce6df5809639e2af450e07c7674 270 Gene3D G3DSA:3.40.190.10 34 130 8.3E-17 T 29-03-2018 CSW12_RS28330 6ea08ce6df5809639e2af450e07c7674 270 SUPERFAMILY SSF53850 34 270 3.44E-78 T 29-03-2018 CSW12_RS28615 ce306a9c0bd49404735b2968b130384d 38 Pfam PF13134 Protein of unknown function (DUF3948) 4 37 1.2E-22 T 29-03-2018 IPR025034 Protein of unknown function DUF3948 CSW12_RS28620 ce306a9c0bd49404735b2968b130384d 38 Pfam PF13134 Protein of unknown function (DUF3948) 4 37 1.2E-22 T 29-03-2018 IPR025034 Protein of unknown function DUF3948 CSW12_RS28625 ce306a9c0bd49404735b2968b130384d 38 Pfam PF13134 Protein of unknown function (DUF3948) 4 37 1.2E-22 T 29-03-2018 IPR025034 Protein of unknown function DUF3948 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 SUPERFAMILY SSF53187 324 406 1.91E-82 T 29-03-2018 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 SUPERFAMILY SSF53187 3 212 1.91E-82 T 29-03-2018 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 Pfam PF07687 Peptidase dimerisation domain 209 308 1.2E-10 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 58.261 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 PIRSF PIRSF037215 1 410 1.6E-193 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 2.9E-200 T 29-03-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 Gene3D G3DSA:3.40.630.10 1 410 8.3E-52 T 29-03-2018 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 Pfam PF01546 Peptidase family M20/M25/M40 141 404 3.7E-12 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 SUPERFAMILY SSF55031 211 322 2.62E-38 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS09075 28120dc849a3cb99284509767ad4629e 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 29-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CSW12_RS30865 054f115a7d154e1c57f519ed44637364 203 Pfam PF13411 MerR HTH family regulatory protein 6 72 3.2E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS30865 054f115a7d154e1c57f519ed44637364 203 Gene3D G3DSA:1.10.1660.10 1 186 7.5E-11 T 29-03-2018 CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 Pfam PF06445 GyrI-like small molecule binding domain 194 265 8.0E-9 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 SUPERFAMILY SSF55136 150 265 3.49E-14 T 29-03-2018 CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 SMART SM00871 123 265 1.1E-10 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 Gene3D G3DSA:3.20.80.10 126 265 3.3E-23 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 Gene3D G3DSA:1.10.1660.10 1 59 4.2E-18 T 29-03-2018 CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 SMART SM00422 2 72 1.4E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 Pfam PF13411 MerR HTH family regulatory protein 3 71 2.0E-13 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 SUPERFAMILY SSF46955 2 105 4.76E-23 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS14370 c6f1246c443aea7d8f12d29ed47129c4 265 Gene3D G3DSA:1.10.1660.10 60 125 2.2E-5 T 29-03-2018 CSW12_RS19330 4f244d6ee44fdeea82abb221f51d5153 434 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 25 433 2.0E-190 T 29-03-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS19330 4f244d6ee44fdeea82abb221f51d5153 434 SMART SM00382 157 337 2.8E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS19330 4f244d6ee44fdeea82abb221f51d5153 434 Gene3D G3DSA:3.40.50.300 44 353 6.6E-74 T 29-03-2018 CSW12_RS19330 4f244d6ee44fdeea82abb221f51d5153 434 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 3 433 2.4E-144 T 29-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS19330 4f244d6ee44fdeea82abb221f51d5153 434 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 353 7.2E-62 T 29-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CSW12_RS19330 4f244d6ee44fdeea82abb221f51d5153 434 SUPERFAMILY SSF52540 93 358 7.36E-81 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25090 79804138d70e862188e337421761752e 393 Pfam PF07670 Nucleoside recognition 91 189 1.2E-5 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS25090 79804138d70e862188e337421761752e 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 5.9E-20 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS25090 79804138d70e862188e337421761752e 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 7.2E-57 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 SUPERFAMILY SSF46955 2 114 2.38E-31 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 Gene3D G3DSA:1.10.1660.10 56 119 3.4E-14 T 29-03-2018 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 Gene3D G3DSA:1.10.1660.10 1 55 7.3E-23 T 29-03-2018 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 Pfam PF13411 MerR HTH family regulatory protein 2 67 1.5E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 SMART SM00422 2 70 9.9E-20 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.0E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 5.0E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03505 3d5709f51b6e1ea99401c55c2dfc9f0e 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 5.0E-7 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS13265 2058cad27ea082dcb9b112fae1b36d4f 404 Pfam PF07690 Major Facilitator Superfamily 17 236 2.2E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS13265 2058cad27ea082dcb9b112fae1b36d4f 404 Pfam PF07690 Major Facilitator Superfamily 250 388 9.3E-15 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS13265 2058cad27ea082dcb9b112fae1b36d4f 404 Gene3D G3DSA:1.20.1250.20 2 199 5.4E-29 T 29-03-2018 CSW12_RS13265 2058cad27ea082dcb9b112fae1b36d4f 404 SUPERFAMILY SSF103473 9 394 3.01E-55 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS13265 2058cad27ea082dcb9b112fae1b36d4f 404 Gene3D G3DSA:1.20.1250.20 200 403 1.5E-19 T 29-03-2018 CSW12_RS14275 c8e34db81cdf364f1733af643bd33578 402 Gene3D G3DSA:1.20.1250.20 197 400 3.9E-27 T 29-03-2018 CSW12_RS14275 c8e34db81cdf364f1733af643bd33578 402 SUPERFAMILY SSF103473 6 392 2.09E-50 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS14275 c8e34db81cdf364f1733af643bd33578 402 Pfam PF07690 Major Facilitator Superfamily 20 329 6.8E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS14275 c8e34db81cdf364f1733af643bd33578 402 Gene3D G3DSA:1.20.1250.20 1 188 1.4E-18 T 29-03-2018 CSW12_RS13050 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 SUPERFAMILY SSF48452 7 132 4.17E-13 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS13050 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 Gene3D G3DSA:1.25.40.10 52 145 9.8E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS13050 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 Gene3D G3DSA:3.30.70.100 2 51 0.0062 T 29-03-2018 CSW12_RS13050 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 SMART SM00028 37 72 85.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS13050 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 SMART SM00028 74 107 0.12 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS13050 eff5d3a7c9cd11fe43a6d1c4b71dcae8 160 Pfam PF12688 Tetratrico peptide repeat 40 155 1.2E-13 T 29-03-2018 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 SUPERFAMILY SSF103473 2 380 1.96E-67 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 PRINTS PR01035 Tetracycline resistance protein signature 129 151 1.7E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 PRINTS PR01035 Tetracycline resistance protein signature 14 30 1.7E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 PRINTS PR01035 Tetracycline resistance protein signature 324 347 1.7E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 PRINTS PR01035 Tetracycline resistance protein signature 157 177 1.7E-5 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 Pfam PF07690 Major Facilitator Superfamily 9 318 1.3E-38 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 Gene3D G3DSA:1.20.1250.20 1 188 2.3E-36 T 29-03-2018 CSW12_RS17840 229c5be9ba21c9b56801aeef691687ef 391 Gene3D G3DSA:1.20.1250.20 189 380 3.5E-22 T 29-03-2018 CSW12_RS03540 c8e622354e6b394d493fa56b827290a4 182 SUPERFAMILY SSF52218 1 180 1.16E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS03540 c8e622354e6b394d493fa56b827290a4 182 Gene3D G3DSA:3.40.50.360 1 182 1.9E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS03540 c8e622354e6b394d493fa56b827290a4 182 Pfam PF02525 Flavodoxin-like fold 2 176 2.2E-36 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS09045 1647b1ed3775cb6f310e42323103551d 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 353 26.666 T 29-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS09045 1647b1ed3775cb6f310e42323103551d 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 139 9.7E-34 T 29-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS09045 1647b1ed3775cb6f310e42323103551d 354 Gene3D G3DSA:3.40.50.2000 186 338 6.8E-23 T 29-03-2018 CSW12_RS09045 1647b1ed3775cb6f310e42323103551d 354 SUPERFAMILY SSF53756 3 336 4.19E-88 T 29-03-2018 CSW12_RS09045 1647b1ed3775cb6f310e42323103551d 354 Gene3D G3DSA:3.40.50.2000 1 185 3.5E-28 T 29-03-2018 CSW12_RS09045 1647b1ed3775cb6f310e42323103551d 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 334 2.9E-28 T 29-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CSW12_RS19570 4f20749429b454677bea514191f952a1 82 Pfam PF10819 Protein of unknown function (DUF2564) 5 82 2.0E-33 T 29-03-2018 IPR020314 Uncharacterised protein family YpzA CSW12_RS19570 4f20749429b454677bea514191f952a1 82 ProDom PD062992 CYTOSOLIC YPZA BH2151 1 82 2.0E-41 T 29-03-2018 IPR020314 Uncharacterised protein family YpzA CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 Gene3D G3DSA:1.20.5.40 106 124 4.6E-18 T 29-03-2018 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 Pfam PF02796 Helix-turn-helix domain of resolvase 139 179 9.3E-9 T 29-03-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 Gene3D G3DSA:1.10.10.60 125 181 2.7E-10 T 29-03-2018 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 Gene3D G3DSA:3.40.50.1390 1 105 5.6E-33 T 29-03-2018 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 SUPERFAMILY SSF53041 1 137 1.23E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 SUPERFAMILY SSF46689 140 178 8.33E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 SMART SM00857 2 137 1.4E-57 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS30305 8ab8ace5b9db0a407405f5a8e7eb04bc 181 Pfam PF00239 Resolvase, N terminal domain 3 137 2.4E-44 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 SUPERFAMILY SSF52821 147 273 7.99E-33 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 Gene3D G3DSA:3.40.250.10 1 145 4.1E-31 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 SUPERFAMILY SSF52821 2 150 3.67E-41 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 Pfam PF00581 Rhodanese-like domain 155 265 1.6E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 Pfam PF00581 Rhodanese-like domain 4 125 8.6E-22 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 SMART SM00450 3 129 4.0E-21 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 SMART SM00450 153 270 8.1E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS19715 4d168135b9dac7a6b083adb10404cdf3 277 Gene3D G3DSA:3.40.250.10 146 277 1.7E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 Gene3D G3DSA:3.40.190.10 201 344 1.2E-36 T 29-03-2018 CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 Gene3D G3DSA:3.90.76.10 93 200 3.7E-28 T 29-03-2018 CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 Gene3D G3DSA:3.10.105.10 345 553 4.3E-48 T 29-03-2018 CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 501 2.9E-88 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 PIRSF PIRSF002741 4 585 3.2E-94 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 SUPERFAMILY SSF53850 56 580 1.19E-117 T 29-03-2018 CSW12_RS01985 8d53790735ec45146953b7b92a585d3e 591 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 109 131 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CSW12_RS15280 b5ea441964ae64b6664b8a6ebbe9c8d6 362 SUPERFAMILY SSF51735 1 78 3.15E-10 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS15280 b5ea441964ae64b6664b8a6ebbe9c8d6 362 Gene3D G3DSA:3.40.50.720 1 314 2.9E-9 T 29-03-2018 CSW12_RS17425 132abdf5785d486d3d8ccea303b20437 142 Gene3D G3DSA:3.40.630.30 1 140 2.0E-18 T 29-03-2018 CSW12_RS17425 132abdf5785d486d3d8ccea303b20437 142 SUPERFAMILY SSF55729 1 138 1.52E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17425 132abdf5785d486d3d8ccea303b20437 142 Pfam PF00583 Acetyltransferase (GNAT) family 45 132 2.1E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 SMART SM00904 185 311 8.5E-62 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 Pfam PF01687 Riboflavin kinase 186 310 2.3E-38 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 Gene3D G3DSA:2.40.30.30 182 322 8.0E-42 T 29-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 310 1.9E-95 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 Gene3D G3DSA:3.40.50.620 4 181 8.5E-37 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 Pfam PF06574 FAD synthetase 18 169 1.3E-47 T 29-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 PIRSF PIRSF004491 2 317 9.0E-106 T 29-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 SUPERFAMILY SSF52374 19 178 8.16E-29 T 29-03-2018 CSW12_RS08735 221a4a9c58a3b0258985dcf2019c685c 323 SUPERFAMILY SSF82114 176 314 4.58E-47 T 29-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CSW12_RS17960 af9b4d39d2d9e27a04549a4851e9b89e 180 Gene3D G3DSA:3.40.630.30 4 168 1.3E-22 T 29-03-2018 CSW12_RS17960 af9b4d39d2d9e27a04549a4851e9b89e 180 Pfam PF00583 Acetyltransferase (GNAT) family 44 144 1.1E-10 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17960 af9b4d39d2d9e27a04549a4851e9b89e 180 SUPERFAMILY SSF55729 1 145 4.46E-25 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS25220 6b2b1322ca9dbbe155bf258d53430849 134 Hamap MF_01048 Protein PsiE [psiE]. 1 134 26.344 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 CSW12_RS25220 6b2b1322ca9dbbe155bf258d53430849 134 Pfam PF06146 Phosphate-starvation-inducible E 57 121 7.8E-17 T 29-03-2018 IPR020948 Phosphate-starvation-induced PsiE-like CSW12_RS25220 6b2b1322ca9dbbe155bf258d53430849 134 PIRSF PIRSF029598 1 134 6.1E-51 T 29-03-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Gene3D G3DSA:3.10.28.10 112 212 2.6E-19 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 1.2E-35 T 29-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 SUPERFAMILY SSF55608 120 221 2.89E-20 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.693 T 29-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 3.0E-37 T 29-03-2018 CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 18 103 4.0E-37 T 29-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 2.6E-137 T 29-03-2018 IPR033981 Sporulation regulator WhiA-like CSW12_RS25460 fc7bcac20d2cd0a0c85fc7cce1985948 316 Gene3D G3DSA:3.10.28.10 2 105 5.0E-14 T 29-03-2018 IPR027434 Homing endonuclease GO:0004519 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 SUPERFAMILY SSF56327 151 309 6.77E-52 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 47.449 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 3.8E-42 T 29-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 8.8E-28 T 29-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 SUPERFAMILY SSF51735 2 147 5.65E-48 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 Gene3D G3DSA:3.90.110.10 150 312 5.4E-48 T 29-03-2018 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 PIRSF PIRSF000102 2 311 9.5E-106 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 5.8E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 5.8E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 5.8E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 5.8E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 5.8E-31 T 29-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 Gene3D G3DSA:3.40.50.720 7 149 1.4E-40 T 29-03-2018 CSW12_RS22585 193c4602f60c756b2c666286c2f57e29 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 4.4E-163 T 29-03-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CSW12_RS19290 f97cf22701b9d973c4dee923b14e9fbf 319 Gene3D G3DSA:3.30.70.260 80 179 0.028 T 29-03-2018 CSW12_RS19290 f97cf22701b9d973c4dee923b14e9fbf 319 Pfam PF12181 DNA binding domain of the motility gene repressor (MogR) 16 163 4.1E-77 T 29-03-2018 IPR021009 Motility repressor, MogR CSW12_RS12105 bc0610a6b1b8535dbc6cc1a97f812eb7 316 Gene3D G3DSA:1.20.58.340 121 232 0.0015 T 29-03-2018 CSW12_RS12105 bc0610a6b1b8535dbc6cc1a97f812eb7 316 Pfam PF01544 CorA-like Mg2+ transporter protein 57 295 2.6E-36 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CSW12_RS12105 bc0610a6b1b8535dbc6cc1a97f812eb7 316 Gene3D G3DSA:1.20.58.340 233 300 5.0E-17 T 29-03-2018 CSW12_RS12105 bc0610a6b1b8535dbc6cc1a97f812eb7 316 SUPERFAMILY SSF143865 73 225 1.96E-9 T 29-03-2018 CSW12_RS12105 bc0610a6b1b8535dbc6cc1a97f812eb7 316 SUPERFAMILY SSF144083 236 297 3.53E-17 T 29-03-2018 CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 Gene3D G3DSA:3.40.50.720 1 237 1.8E-58 T 29-03-2018 CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 9.0E-46 T 29-03-2018 CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 1.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.0E-36 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS08850 f62dac1be23f1833d3d682440ce3004b 237 SUPERFAMILY SSF51735 2 236 2.4E-63 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS23090 b38eeced932751b8be91560c1c4e1349 134 Pfam PF06713 Bacterial PH domain 62 123 1.9E-9 T 29-03-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 CSW12_RS24370 65edea61f93d8fd9e51261b1a668c9ff 247 Gene3D G3DSA:3.30.565.40 20 151 4.0E-26 T 29-03-2018 CSW12_RS24370 65edea61f93d8fd9e51261b1a668c9ff 247 Pfam PF11738 Protein of unknown function (DUF3298) 154 228 4.4E-18 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CSW12_RS24370 65edea61f93d8fd9e51261b1a668c9ff 247 Gene3D G3DSA:3.90.640.20 152 247 6.4E-23 T 29-03-2018 IPR021729 Domain of unknown function DUF3298 CSW12_RS24370 65edea61f93d8fd9e51261b1a668c9ff 247 Pfam PF13739 Domain of unknown function (DUF4163) 40 135 1.7E-23 T 29-03-2018 IPR025303 Deacetylase PdaC CSW12_RS07715 5cbfc69fc0f979b6438c307263ff3394 129 Pfam PF11033 Competence protein J (ComJ) 2 126 8.7E-52 T 29-03-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ CSW12_RS07715 5cbfc69fc0f979b6438c307263ff3394 129 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 3 106 2.0E-54 T 29-03-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 193 9.7E-32 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 SUPERFAMILY SSF100939 2 260 2.94E-39 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 TIGRFAM TIGR02772 Ku_bact: Ku protein 2 258 3.2E-74 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 SMART SM00559 53 182 8.0E-23 T 29-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 PIRSF PIRSF006493 1 270 3.5E-77 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 255 29.133 T 29-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CSW12_RS03390 54e3c35d4b6e3b57be8e587ce3db4dda 270 Gene3D G3DSA:2.40.290.10 1 184 1.5E-24 T 29-03-2018 IPR016194 SPOC-like, C-terminal domain CSW12_RS17710 72c6d0c60b15122fad9de3720cebda08 138 SUPERFAMILY SSF54593 3 129 3.09E-25 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS17710 72c6d0c60b15122fad9de3720cebda08 138 Gene3D G3DSA:3.10.180.10 1 135 9.7E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS17710 72c6d0c60b15122fad9de3720cebda08 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 116 5.2E-12 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS17710 72c6d0c60b15122fad9de3720cebda08 138 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 1 138 42.825 T 29-03-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 CSW12_RS12080 ed3720b61e4434345482e2deca7cefae 121 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 113 6.1E-8 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS12080 ed3720b61e4434345482e2deca7cefae 121 SUPERFAMILY SSF159121 27 117 1.1E-17 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS12080 ed3720b61e4434345482e2deca7cefae 121 Pfam PF06486 Protein of unknown function (DUF1093) 34 106 1.2E-8 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS12425 f37128cb3e074bf18728f10fddb2f289 265 Pfam PF13468 Glyoxalase-like domain 4 193 1.3E-45 T 29-03-2018 IPR025870 Glyoxalase-like domain CSW12_RS12425 f37128cb3e074bf18728f10fddb2f289 265 Gene3D G3DSA:3.10.180.10 166 250 4.5E-4 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12425 f37128cb3e074bf18728f10fddb2f289 265 SUPERFAMILY SSF54593 2 148 3.48E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12425 f37128cb3e074bf18728f10fddb2f289 265 Gene3D G3DSA:3.10.180.10 1 137 3.4E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 254 2.3E-50 T 29-03-2018 CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 Gene3D G3DSA:3.40.50.720 12 257 6.4E-57 T 29-03-2018 CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 6.0E-30 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.4E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.4E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 2.4E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS22745 abe887ddaf0436fc4807fbe60edaf3f6 263 SUPERFAMILY SSF51735 13 254 8.76E-64 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 Pfam PF00905 Penicillin binding protein transpeptidase domain 257 564 1.5E-83 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 Gene3D G3DSA:3.40.710.10 230 597 1.6E-83 T 29-03-2018 CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 SMART SM00740 586 645 1.4E-4 T 29-03-2018 IPR005543 PASTA domain CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 SMART SM00740 646 701 0.18 T 29-03-2018 IPR005543 PASTA domain CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 SUPERFAMILY SSF54184 647 699 1.03E-11 T 29-03-2018 CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 Gene3D G3DSA:3.90.1310.10 22 229 9.3E-35 T 29-03-2018 CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 SUPERFAMILY SSF56601 180 580 6.54E-90 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 Pfam PF03793 PASTA domain 591 641 1.2E-8 T 29-03-2018 IPR005543 PASTA domain CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 Pfam PF03793 PASTA domain 647 699 1.9E-8 T 29-03-2018 IPR005543 PASTA domain CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 Pfam PF03717 Penicillin-binding Protein dimerisation domain 57 207 2.5E-18 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 SUPERFAMILY SSF56519 55 228 4.32E-38 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS14425 69fd26e328f3f0e1f78ee2d60f6a3be6 712 SUPERFAMILY SSF54184 586 644 1.1E-11 T 29-03-2018 CSW12_RS24290 ea8aa25ec7d391f9b5d13fbeecd124fc 114 SUPERFAMILY SSF50249 4 89 6.99E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS24290 ea8aa25ec7d391f9b5d13fbeecd124fc 114 SMART SM00316 6 77 3.4E-25 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS24290 ea8aa25ec7d391f9b5d13fbeecd124fc 114 PRINTS PR00681 Ribosomal protein S1 signature 60 78 6.8E-12 T 29-03-2018 CSW12_RS24290 ea8aa25ec7d391f9b5d13fbeecd124fc 114 PRINTS PR00681 Ribosomal protein S1 signature 21 40 6.8E-12 T 29-03-2018 CSW12_RS24290 ea8aa25ec7d391f9b5d13fbeecd124fc 114 Gene3D G3DSA:2.40.50.140 9 109 6.7E-27 T 29-03-2018 CSW12_RS24290 ea8aa25ec7d391f9b5d13fbeecd124fc 114 Pfam PF00575 S1 RNA binding domain 7 77 2.9E-20 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS17320 b619421e10ed8a4b83a96427cbd710cb 323 SMART SM00849 24 228 1.5E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS17320 b619421e10ed8a4b83a96427cbd710cb 323 Pfam PF00753 Metallo-beta-lactamase superfamily 32 228 1.1E-17 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS17320 b619421e10ed8a4b83a96427cbd710cb 323 SUPERFAMILY SSF56281 4 270 3.14E-46 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS17320 b619421e10ed8a4b83a96427cbd710cb 323 Gene3D G3DSA:3.60.15.10 1 287 1.9E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS04875 6e210f6b8055132fd0b3cd5f7fb9f6dd 99 Pfam PF09874 Predicted membrane protein (DUF2101) 9 77 7.4E-5 T 29-03-2018 IPR018663 Protein of unknown function DUF2101, membrane CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 SMART SM00448 5 115 5.1E-46 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 SMART SM00862 156 233 2.1E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 SUPERFAMILY SSF52172 3 124 3.13E-42 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 Gene3D G3DSA:3.40.50.2300 1 132 1.0E-38 T 29-03-2018 CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 9.1E-28 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 SUPERFAMILY SSF46894 133 234 1.91E-31 T 29-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 Pfam PF00072 Response regulator receiver domain 7 115 2.3E-31 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS06970 0379bdb4fd4a30de5632b76c053c0874 238 Gene3D G3DSA:1.10.10.10 133 238 1.1E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14780 f8077f31127ad4c73b87e4cd3d8a2ada 233 Pfam PF13649 Methyltransferase domain 53 154 1.6E-13 T 29-03-2018 CSW12_RS14780 f8077f31127ad4c73b87e4cd3d8a2ada 233 Gene3D G3DSA:3.40.50.150 1 226 5.3E-20 T 29-03-2018 CSW12_RS14780 f8077f31127ad4c73b87e4cd3d8a2ada 233 SUPERFAMILY SSF53335 24 194 2.56E-23 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS19635 c0f60eb8a93f9a2e591f036728fd3bad 269 Gene3D G3DSA:3.90.550.10 3 268 1.1E-46 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS19635 c0f60eb8a93f9a2e591f036728fd3bad 269 SUPERFAMILY SSF53448 15 233 6.0E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS19635 c0f60eb8a93f9a2e591f036728fd3bad 269 Pfam PF00535 Glycosyl transferase family 2 18 143 2.3E-34 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 SUPERFAMILY SSF56801 9 481 9.55E-108 T 29-03-2018 CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 Pfam PF13193 AMP-binding enzyme C-terminal domain 398 469 5.2E-17 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 Gene3D G3DSA:3.40.50.980 3 153 1.9E-25 T 29-03-2018 CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 Pfam PF00501 AMP-binding enzyme 9 387 4.1E-64 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 Gene3D G3DSA:2.30.38.10 300 382 1.2E-18 T 29-03-2018 CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 Gene3D G3DSA:3.30.300.30 383 483 1.8E-24 T 29-03-2018 CSW12_RS09615 099f69a682ba840880af3353b29ad555 487 Gene3D G3DSA:3.40.50.980 154 299 4.9E-25 T 29-03-2018 CSW12_RS30295 493834d6ba9ff1138576a0ee2ad89542 241 Pfam PF05547 Immune inhibitor A peptidase M6 63 235 1.7E-33 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS29450 01c92c34e5455aedc62fd0208e7f0ccd 617 PIRSF PIRSF018968 1 394 3.1E-40 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS29450 01c92c34e5455aedc62fd0208e7f0ccd 617 PIRSF PIRSF018968 420 615 1.3E-22 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS29450 01c92c34e5455aedc62fd0208e7f0ccd 617 Pfam PF02687 FtsX-like permease family 84 179 3.7E-10 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS02400 635f46c2720bfa34fe5e13c5dd2a8b0c 270 Gene3D G3DSA:3.40.50.300 37 267 2.9E-11 T 29-03-2018 CSW12_RS02400 635f46c2720bfa34fe5e13c5dd2a8b0c 270 SUPERFAMILY SSF52540 115 240 7.73E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02400 635f46c2720bfa34fe5e13c5dd2a8b0c 270 Pfam PF00308 Bacterial dnaA protein 114 236 1.0E-8 T 29-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CSW12_RS18845 ddd8b6ece7223c0b5caaf90a217a83fa 312 SUPERFAMILY SSF52540 3 222 4.19E-67 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18845 ddd8b6ece7223c0b5caaf90a217a83fa 312 Pfam PF13732 Domain of unknown function (DUF4162) 217 304 9.2E-7 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CSW12_RS18845 ddd8b6ece7223c0b5caaf90a217a83fa 312 SMART SM00382 28 210 1.0E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS18845 ddd8b6ece7223c0b5caaf90a217a83fa 312 Gene3D G3DSA:3.40.50.300 1 279 7.0E-71 T 29-03-2018 CSW12_RS18845 ddd8b6ece7223c0b5caaf90a217a83fa 312 Pfam PF00005 ABC transporter 19 162 2.9E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18845 ddd8b6ece7223c0b5caaf90a217a83fa 312 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS29340 2db57d6564fd113d1c169f73642d4bb1 218 SUPERFAMILY SSF46785 3 69 2.38E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29340 2db57d6564fd113d1c169f73642d4bb1 218 Gene3D G3DSA:1.10.10.10 4 65 1.6E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29340 2db57d6564fd113d1c169f73642d4bb1 218 Pfam PF13814 Replication-relaxation 72 156 2.2E-7 T 29-03-2018 IPR025855 Plasmid replication-relaxation CSW12_RS27900 71fa525d791937b1ebe61bdc877cda7e 48 Pfam PF00471 Ribosomal protein L33 3 48 9.2E-18 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27900 71fa525d791937b1ebe61bdc877cda7e 48 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 48 7.3E-16 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27900 71fa525d791937b1ebe61bdc877cda7e 48 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 48 17.515 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS27900 71fa525d791937b1ebe61bdc877cda7e 48 SUPERFAMILY SSF57829 1 48 4.09E-15 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CSW12_RS03375 526e8e9d256209772b3b290363da10f9 71 Pfam PF11007 Spore coat associated protein JA (CotJA) 28 63 3.1E-9 T 29-03-2018 IPR020256 Spore coat protein CotJA CSW12_RS03375 526e8e9d256209772b3b290363da10f9 71 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 5 71 9.0E-33 T 29-03-2018 IPR020256 Spore coat protein CotJA CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 SUPERFAMILY SSF51338 5 64 2.38E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 SUPERFAMILY SSF51338 495 540 2.38E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 Pfam PF07969 Amidohydrolase family 54 536 5.8E-107 T 29-03-2018 IPR013108 Amidohydrolase 3 CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 Gene3D G3DSA:2.30.40.10 3 82 2.3E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 Gene3D G3DSA:3.20.20.140 195 477 2.0E-30 T 29-03-2018 CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 SUPERFAMILY SSF51556 63 125 1.13E-42 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 SUPERFAMILY SSF51556 205 496 1.13E-42 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS12130 50a3d0710cab3be932468a65b67f56d9 613 Gene3D G3DSA:2.30.40.10 478 540 7.9E-6 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS27245 b00f75b4f3deb0375f9ed387088dd6fc 65 PIRSF PIRSF037263 1 65 1.0E-34 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CSW12_RS27245 b00f75b4f3deb0375f9ed387088dd6fc 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 60 1.8E-29 T 29-03-2018 IPR009296 Protein of unknown function DUF951 CSW12_RS00485 257e1c26affba48adcffcaa8e77ca2fe 398 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 190 397 3.7E-53 T 29-03-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 CSW12_RS00485 257e1c26affba48adcffcaa8e77ca2fe 398 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 4.5E-17 T 29-03-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 CSW12_RS31070 84b392f9277b4da2a6de3866c7d5e1ad 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 6.1E-13 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS31070 84b392f9277b4da2a6de3866c7d5e1ad 92 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 48 7.7E-13 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS31070 84b392f9277b4da2a6de3866c7d5e1ad 92 Gene3D G3DSA:2.10.260.10 1 48 2.2E-21 T 29-03-2018 CSW12_RS31070 84b392f9277b4da2a6de3866c7d5e1ad 92 SMART SM00966 8 51 5.5E-11 T 29-03-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CSW12_RS31070 84b392f9277b4da2a6de3866c7d5e1ad 92 SUPERFAMILY SSF89447 1 49 3.53E-16 T 29-03-2018 CSW12_RS10140 1caac3572eacefbbfd7fb3c2f0c10ba6 606 Gene3D G3DSA:3.30.70.270 109 366 1.0E-38 T 29-03-2018 CSW12_RS10140 1caac3572eacefbbfd7fb3c2f0c10ba6 606 Pfam PF01348 Type II intron maturase 410 488 7.5E-11 T 29-03-2018 IPR024937 Domain X GO:0006397 CSW12_RS10140 1caac3572eacefbbfd7fb3c2f0c10ba6 606 Gene3D G3DSA:3.40.1800.10 530 605 4.6E-5 T 29-03-2018 CSW12_RS10140 1caac3572eacefbbfd7fb3c2f0c10ba6 606 SUPERFAMILY SSF56672 21 235 5.86E-46 T 29-03-2018 CSW12_RS10140 1caac3572eacefbbfd7fb3c2f0c10ba6 606 SUPERFAMILY SSF56672 303 370 5.86E-46 T 29-03-2018 CSW12_RS10140 1caac3572eacefbbfd7fb3c2f0c10ba6 606 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 88 234 4.7E-34 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS18920 eba6d2167e5fc7d9a1c96064e177cd15 237 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 13 216 2.9E-54 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CSW12_RS13765 528fb43cb3befddcd1c9531fc8d65dfa 112 Pfam PF13789 Domain of unknown function (DUF4181) 3 103 9.0E-18 T 29-03-2018 IPR025441 Protein of unknown function DUF4181 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 Gene3D G3DSA:1.20.810.10 17 174 5.3E-28 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 Gene3D G3DSA:1.10.760.10 177 255 2.3E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 SUPERFAMILY SSF46626 141 252 9.03E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 1.6E-12 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 81 160 1.8E-9 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 PIRSF PIRSF036636 1 255 5.2E-154 T 29-03-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CSW12_RS19980 4a52efc71da1ed7933fb4fd602aff2ce 255 SUPERFAMILY SSF81648 21 156 7.46E-30 T 29-03-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CSW12_RS19310 158a1ce87b97d513b8c4b2655616ff42 437 Gene3D G3DSA:2.60.98.20 7 316 4.5E-4 T 29-03-2018 IPR011491 Flagellar hook protein FlgE CSW12_RS19310 158a1ce87b97d513b8c4b2655616ff42 437 Pfam PF07559 Flagellar basal body protein FlaE 186 312 2.1E-6 T 29-03-2018 IPR011491 Flagellar hook protein FlgE CSW12_RS19310 158a1ce87b97d513b8c4b2655616ff42 437 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 418 5.8E-69 T 29-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CSW12_RS19310 158a1ce87b97d513b8c4b2655616ff42 437 SUPERFAMILY SSF117143 94 397 1.83E-50 T 29-03-2018 CSW12_RS19310 158a1ce87b97d513b8c4b2655616ff42 437 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 358 435 3.8E-14 T 29-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CSW12_RS19310 158a1ce87b97d513b8c4b2655616ff42 437 Pfam PF00460 Flagella basal body rod protein 5 35 3.8E-10 T 29-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CSW12_RS14390 5e0a1bf71e169d1260bf7111af489325 141 SUPERFAMILY SSF54427 3 134 9.19E-27 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS14390 5e0a1bf71e169d1260bf7111af489325 141 Pfam PF07366 SnoaL-like polyketide cyclase 7 134 1.3E-26 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CSW12_RS14390 5e0a1bf71e169d1260bf7111af489325 141 Gene3D G3DSA:3.10.450.50 2 137 3.3E-16 T 29-03-2018 CSW12_RS05595 e2dfc22a4665249e113958e8513bd507 229 SUPERFAMILY SSF53335 14 194 6.57E-37 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS05595 e2dfc22a4665249e113958e8513bd507 229 Gene3D G3DSA:3.40.50.150 21 229 6.7E-33 T 29-03-2018 CSW12_RS05595 e2dfc22a4665249e113958e8513bd507 229 Pfam PF13489 Methyltransferase domain 29 178 2.9E-17 T 29-03-2018 CSW12_RS23190 524669251e1a8c8f530bc1b737dabbcb 265 Gene3D G3DSA:3.90.1200.10 33 263 7.6E-23 T 29-03-2018 CSW12_RS23190 524669251e1a8c8f530bc1b737dabbcb 265 Pfam PF01636 Phosphotransferase enzyme family 45 230 2.7E-20 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS23190 524669251e1a8c8f530bc1b737dabbcb 265 SUPERFAMILY SSF56112 3 231 1.22E-30 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS06250 3d94ac13810f1a1e0df020e3053def7d 220 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 1.7E-84 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CSW12_RS06250 3d94ac13810f1a1e0df020e3053def7d 220 PIRSF PIRSF006293 2 218 4.6E-78 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CSW12_RS06250 3d94ac13810f1a1e0df020e3053def7d 220 SUPERFAMILY SSF52402 3 211 6.4E-70 T 29-03-2018 CSW12_RS06250 3d94ac13810f1a1e0df020e3053def7d 220 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 217 52.531 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CSW12_RS06250 3d94ac13810f1a1e0df020e3053def7d 220 Gene3D G3DSA:3.40.50.620 3 219 1.7E-54 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS06250 3d94ac13810f1a1e0df020e3053def7d 220 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 4.0E-86 T 29-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CSW12_RS05570 7a356b67d1c30ce79bdfdd0bee9aa1b3 308 SUPERFAMILY SSF53448 8 252 2.42E-47 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05570 7a356b67d1c30ce79bdfdd0bee9aa1b3 308 Pfam PF00535 Glycosyl transferase family 2 11 132 9.2E-22 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS05570 7a356b67d1c30ce79bdfdd0bee9aa1b3 308 Gene3D G3DSA:3.90.550.10 2 308 2.5E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS27060 1dea5dd8df5c8de720671531327b4f39 117 Gene3D G3DSA:1.10.10.10 1 107 2.1E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27060 1dea5dd8df5c8de720671531327b4f39 117 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 9.6E-19 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS27060 1dea5dd8df5c8de720671531327b4f39 117 SUPERFAMILY SSF46785 10 102 4.0E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08100 c5fc60b3ff52f1292c7ba6df47978e13 188 Pfam PF03602 Conserved hypothetical protein 95 1 181 5.7E-58 T 29-03-2018 CSW12_RS08100 c5fc60b3ff52f1292c7ba6df47978e13 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CSW12_RS08100 c5fc60b3ff52f1292c7ba6df47978e13 188 PIRSF PIRSF004553 1 184 2.3E-50 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CSW12_RS08100 c5fc60b3ff52f1292c7ba6df47978e13 188 SUPERFAMILY SSF53335 1 181 1.32E-50 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS08100 c5fc60b3ff52f1292c7ba6df47978e13 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 3.8E-53 T 29-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CSW12_RS08100 c5fc60b3ff52f1292c7ba6df47978e13 188 Gene3D G3DSA:3.40.50.150 1 184 6.4E-32 T 29-03-2018 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 SUPERFAMILY SSF46785 4 130 1.37E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 SMART SM00347 21 120 7.6E-17 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 Gene3D G3DSA:1.10.10.10 1 98 7.0E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 Pfam PF01047 MarR family 28 85 7.3E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 6.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 6.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 44 60 6.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 6.6E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS06505 5ded4cd33cf3eac38e0f8b5897abe116 131 Gene3D G3DSA:1.10.287.100 99 131 6.5E-7 T 29-03-2018 CSW12_RS14345 b1430605f789e4f6f8ddb12975e0c406 291 SUPERFAMILY SSF51695 38 285 6.8E-75 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS14345 b1430605f789e4f6f8ddb12975e0c406 291 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 44 279 2.1E-49 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CSW12_RS14345 b1430605f789e4f6f8ddb12975e0c406 291 Gene3D G3DSA:3.20.20.190 17 291 4.7E-78 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS28380 ec2d57defed5c752f061f8f8e918d1df 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 302 1.6E-41 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28380 ec2d57defed5c752f061f8f8e918d1df 305 SUPERFAMILY SSF161098 88 290 3.27E-16 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28380 ec2d57defed5c752f061f8f8e918d1df 305 Gene3D G3DSA:1.10.3720.10 2 291 8.3E-38 T 29-03-2018 CSW12_RS04450 70c34bf239a3f7b091a53a209757ff73 149 SMART SM00530 6 61 8.5E-19 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS04450 70c34bf239a3f7b091a53a209757ff73 149 Gene3D G3DSA:1.10.260.40 1 120 5.8E-25 T 29-03-2018 CSW12_RS04450 70c34bf239a3f7b091a53a209757ff73 149 SUPERFAMILY SSF47413 1 67 9.98E-21 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS04450 70c34bf239a3f7b091a53a209757ff73 149 Pfam PF01381 Helix-turn-helix 7 61 6.5E-18 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 Gene3D G3DSA:3.90.230.10 127 354 5.1E-79 T 29-03-2018 CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 SUPERFAMILY SSF53092 1 127 8.63E-27 T 29-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 Gene3D G3DSA:3.40.350.10 1 126 4.1E-26 T 29-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 284 296 - T 29-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 128 6.8E-25 T 29-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 306 318 6.9E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 208 224 6.9E-7 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 SUPERFAMILY SSF55920 86 348 1.7E-83 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS08375 12d4b3258b075514f68ef7e14b4db44a 356 Pfam PF00557 Metallopeptidase family M24 136 338 4.4E-69 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS25620 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 103 6.5E-10 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS25620 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 Gene3D G3DSA:1.10.760.10 20 107 3.6E-13 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS25620 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 SUPERFAMILY SSF46626 8 105 1.86E-15 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS25620 f9ec63a193ac0222e9f80ec6f5e3a4e7 107 PIRSF PIRSF000025 1 107 1.2E-34 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 CSW12_RS04490 95129da2adb023d569f3d13f133597e3 417 Pfam PF01098 Cell cycle protein 80 407 2.3E-30 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CSW12_RS15880 6e228e42cb334e97042a888b64c8f443 295 SUPERFAMILY SSF55729 13 277 4.05E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS15880 6e228e42cb334e97042a888b64c8f443 295 Pfam PF13527 Acetyltransferase (GNAT) domain 16 132 9.5E-19 T 29-03-2018 CSW12_RS15880 6e228e42cb334e97042a888b64c8f443 295 Gene3D G3DSA:3.40.630.30 7 184 4.6E-12 T 29-03-2018 CSW12_RS16075 a5e895721bf388fa0068e397934c901c 334 Gene3D G3DSA:1.10.3720.10 3 293 4.7E-24 T 29-03-2018 CSW12_RS16075 a5e895721bf388fa0068e397934c901c 334 SUPERFAMILY SSF161098 75 280 2.49E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16075 a5e895721bf388fa0068e397934c901c 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 298 1.7E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS06390 f05779636df69947b1c741770c7e467f 363 Gene3D G3DSA:3.20.20.70 2 358 1.1E-58 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS06390 f05779636df69947b1c741770c7e467f 363 Pfam PF03060 Nitronate monooxygenase 5 346 2.2E-94 T 29-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CSW12_RS06390 f05779636df69947b1c741770c7e467f 363 SUPERFAMILY SSF51412 5 361 1.47E-68 T 29-03-2018 CSW12_RS12785 bfb7aa9bedf9c95fd1442e2d6fad1626 260 SMART SM01133 18 228 3.2E-30 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS12785 bfb7aa9bedf9c95fd1442e2d6fad1626 260 PIRSF PIRSF038992 1 258 3.7E-67 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS12785 bfb7aa9bedf9c95fd1442e2d6fad1626 260 Gene3D G3DSA:3.20.20.70 3 258 4.0E-51 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS12785 bfb7aa9bedf9c95fd1442e2d6fad1626 260 SUPERFAMILY SSF51569 4 243 1.43E-61 T 29-03-2018 CSW12_RS12785 bfb7aa9bedf9c95fd1442e2d6fad1626 260 Pfam PF01791 DeoC/LacD family aldolase 19 227 7.7E-26 T 29-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CSW12_RS19415 6159e219d83392e71e90cec4abdeb650 458 Gene3D G3DSA:2.60.40.650 203 410 3.3E-4 T 29-03-2018 CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Pfam PF01551 Peptidase family M23 275 372 1.9E-29 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 SUPERFAMILY SSF51261 242 382 7.85E-42 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Gene3D G3DSA:2.40.50.110 172 233 1.1E-15 T 29-03-2018 CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Gene3D G3DSA:2.40.50.110 21 97 1.6E-12 T 29-03-2018 CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Gene3D G3DSA:2.40.50.110 99 166 7.4E-18 T 29-03-2018 CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Gene3D G3DSA:2.70.70.10 234 384 3.6E-39 T 29-03-2018 CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 SMART SM00287 179 241 6.1E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 SMART SM00287 105 167 1.2E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 SMART SM00287 38 99 0.078 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Pfam PF08239 Bacterial SH3 domain 188 237 1.1E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Pfam PF08239 Bacterial SH3 domain 114 163 1.5E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS02945 86d02dac9025daf86bce3abad9aa1268 384 Pfam PF08239 Bacterial SH3 domain 48 94 3.8E-8 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS19630 3855420e4851986e5e3e3b2309fe57d3 350 Gene3D G3DSA:3.40.50.2000 177 341 1.5E-37 T 29-03-2018 CSW12_RS19630 3855420e4851986e5e3e3b2309fe57d3 350 SUPERFAMILY SSF53756 5 347 8.37E-71 T 29-03-2018 CSW12_RS19630 3855420e4851986e5e3e3b2309fe57d3 350 Gene3D G3DSA:3.40.50.2000 1 176 4.1E-10 T 29-03-2018 CSW12_RS19630 3855420e4851986e5e3e3b2309fe57d3 350 Pfam PF00534 Glycosyl transferases group 1 161 327 3.0E-35 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 SUPERFAMILY SSF55874 226 374 4.98E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 SUPERFAMILY SSF47384 156 227 1.67E-11 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 325 6.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 339 6.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 358 6.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 227 2.8E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 SMART SM00388 167 229 3.3E-10 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 SMART SM00387 271 377 6.7E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 Pfam PF09385 Histidine kinase N terminal 17 144 1.7E-49 T 29-03-2018 IPR018984 Histidine kinase, N-terminal CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 Gene3D G3DSA:3.30.565.10 230 377 4.4E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 Gene3D G3DSA:1.10.287.130 146 225 4.1E-9 T 29-03-2018 CSW12_RS16520 e875cf01ba6bf14092a719fc40fa7944 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 373 1.0E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS12190 d71454c22c44dcf117407a5643649add 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 25 34 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS12190 d71454c22c44dcf117407a5643649add 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 64 5.7E-23 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS12190 d71454c22c44dcf117407a5643649add 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 43 57 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS09100 1ba225791c48dc533c9af4e03d63d66e 321 Pfam PF01497 Periplasmic binding protein 64 292 1.2E-34 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS09100 1ba225791c48dc533c9af4e03d63d66e 321 Gene3D G3DSA:3.40.50.1980 159 321 3.6E-30 T 29-03-2018 CSW12_RS09100 1ba225791c48dc533c9af4e03d63d66e 321 Gene3D G3DSA:3.40.50.1980 43 158 1.0E-23 T 29-03-2018 CSW12_RS09100 1ba225791c48dc533c9af4e03d63d66e 321 SUPERFAMILY SSF53807 50 314 3.02E-58 T 29-03-2018 CSW12_RS26115 51eebef1c2d09dec351fdaac223eb44a 204 Pfam PF02397 Bacterial sugar transferase 7 187 4.7E-63 T 29-03-2018 IPR003362 Bacterial sugar transferase CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF51905 5 246 1.2E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF51905 356 430 1.2E-64 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF56425 230 352 3.14E-31 T 29-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 Gene3D G3DSA:4.10.80.40 532 581 1.9E-7 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 Pfam PF00890 FAD binding domain 5 391 1.8E-87 T 29-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 38 47 - T 29-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 Gene3D G3DSA:3.50.50.60 4 437 8.3E-55 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 395 410 1.1E-6 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.1E-6 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 5 578 3.1E-282 T 29-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 Pfam PF02910 Fumarate reductase flavoprotein C-term 451 578 4.7E-41 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.7E-9 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.7E-9 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 Gene3D G3DSA:1.20.58.100 438 531 6.4E-26 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 PIRSF PIRSF000171 342 575 2.8E-13 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 PIRSF PIRSF000171 1 239 4.2E-18 T 29-03-2018 CSW12_RS22180 d9df694d3e617d8ac8f78d42776d656e 597 SUPERFAMILY SSF46977 442 584 8.76E-46 T 29-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CSW12_RS10810 d6280c3c12bb6e0ab806499bbb87aef6 107 Gene3D G3DSA:1.10.10.10 13 107 9.0E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10810 d6280c3c12bb6e0ab806499bbb87aef6 107 Pfam PF01638 HxlR-like helix-turn-helix 15 100 8.6E-35 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS10810 d6280c3c12bb6e0ab806499bbb87aef6 107 SUPERFAMILY SSF46785 4 102 3.1E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25645 eab4bad99da4d4ff0bc90c58a79f4a5d 212 SUPERFAMILY SSF52540 3 211 1.96E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25645 eab4bad99da4d4ff0bc90c58a79f4a5d 212 Gene3D G3DSA:3.40.50.300 1 212 3.6E-50 T 29-03-2018 CSW12_RS25645 eab4bad99da4d4ff0bc90c58a79f4a5d 212 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25645 eab4bad99da4d4ff0bc90c58a79f4a5d 212 SMART SM00382 29 209 6.7E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25645 eab4bad99da4d4ff0bc90c58a79f4a5d 212 Pfam PF00005 ABC transporter 20 160 1.2E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS21205 3a98e445a39b07b5e42634ed5b5ffce0 379 SUPERFAMILY SSF102114 5 377 1.22E-120 T 29-03-2018 CSW12_RS21205 3a98e445a39b07b5e42634ed5b5ffce0 379 Gene3D G3DSA:3.20.20.70 5 329 2.6E-52 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS21205 3a98e445a39b07b5e42634ed5b5ffce0 379 Pfam PF06969 HemN C-terminal domain 303 365 9.4E-18 T 29-03-2018 IPR010723 HemN, C-terminal CSW12_RS21205 3a98e445a39b07b5e42634ed5b5ffce0 379 SMART SM00729 2 223 7.4E-65 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS21205 3a98e445a39b07b5e42634ed5b5ffce0 379 Pfam PF04055 Radical SAM superfamily 7 177 1.4E-26 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS21205 3a98e445a39b07b5e42634ed5b5ffce0 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 365 4.5E-128 T 29-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CSW12_RS12610 a348336f8dc3bad25319d36f50203e55 387 Pfam PF01882 Protein of unknown function DUF58 213 292 7.6E-12 T 29-03-2018 IPR002881 Domain of unknown function DUF58 CSW12_RS06320 bc71f4631f4cdd406ce519ebd5b7d5fa 257 SMART SM00465 1 94 5.6E-4 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS06320 bc71f4631f4cdd406ce519ebd5b7d5fa 257 Gene3D G3DSA:1.10.10.60 170 234 2.7E-4 T 29-03-2018 CSW12_RS06320 bc71f4631f4cdd406ce519ebd5b7d5fa 257 Gene3D G3DSA:1.10.10.60 99 168 4.8E-8 T 29-03-2018 CSW12_RS06320 bc71f4631f4cdd406ce519ebd5b7d5fa 257 SUPERFAMILY SSF82771 1 93 1.01E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS06320 bc71f4631f4cdd406ce519ebd5b7d5fa 257 Gene3D G3DSA:3.40.1440.10 1 93 5.5E-10 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 282 319 - T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 Gene3D G3DSA:3.90.1150.10 42 227 3.7E-43 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 Pfam PF00202 Aminotransferase class-III 62 465 2.9E-134 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 SUPERFAMILY SSF53383 59 468 8.37E-138 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 Gene3D G3DSA:3.40.640.10 228 352 5.3E-44 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 49 468 2.8E-198 T 29-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 PIRSF PIRSF000521 8 169 7.4E-11 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 PIRSF PIRSF000521 162 470 1.4E-40 T 29-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CSW12_RS00445 b29f6e84beda482d6c024571209f9ccf 479 Gene3D G3DSA:3.90.1150.10 353 470 6.6E-22 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 29-03-2018 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.1E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.1E-7 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 SUPERFAMILY SSF47413 2 59 8.04E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 Gene3D G3DSA:3.40.50.2300 58 162 1.1E-29 T 29-03-2018 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 Gene3D G3DSA:1.10.260.40 2 57 5.0E-21 T 29-03-2018 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 Gene3D G3DSA:3.40.50.2300 163 323 2.0E-50 T 29-03-2018 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 SUPERFAMILY SSF53822 60 323 2.9E-81 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 Pfam PF13377 Periplasmic binding protein-like domain 166 322 2.2E-35 T 29-03-2018 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.7E-21 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS02025 cc75060497b15a75f6c720e0fe267ac6 323 SMART SM00354 1 71 9.9E-36 T 29-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 5 370 5.3E-102 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 Gene3D G3DSA:3.20.20.140 68 347 2.3E-99 T 29-03-2018 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 Gene3D G3DSA:2.30.40.10 1 67 6.2E-12 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 SUPERFAMILY SSF51556 57 346 2.57E-93 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 PIRSF PIRSF038994 1 378 9.5E-117 T 29-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 Pfam PF01979 Amidohydrolase family 53 361 3.1E-23 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 SUPERFAMILY SSF51338 4 56 3.67E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS07410 e3d85e7c57f24dc38aaaa03ab159cb1a 380 SUPERFAMILY SSF51338 347 376 3.67E-13 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS26405 782de983eac5cd0715d14225810a9813 92 Pfam PF13071 Protein of unknown function (DUF3935) 2 71 6.1E-48 T 29-03-2018 IPR025176 Protein of unknown function DUF3935 CSW12_RS14095 5cff0d49a722f6f9f471ce7412ac9299 231 SUPERFAMILY SSF56784 4 223 2.36E-41 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14095 5cff0d49a722f6f9f471ce7412ac9299 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 100 195 6.3E-10 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS14095 5cff0d49a722f6f9f471ce7412ac9299 231 Gene3D G3DSA:3.40.50.1000 2 221 2.9E-31 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14095 5cff0d49a722f6f9f471ce7412ac9299 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 195 8.8E-31 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14095 5cff0d49a722f6f9f471ce7412ac9299 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 111 190 4.8E-17 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 Pfam PF00355 Rieske [2Fe-2S] domain 51 149 4.2E-14 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 121 133 1.5E-5 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 97 108 1.5E-5 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 145 1.5E-5 T 29-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 SUPERFAMILY SSF50022 6 160 1.57E-30 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 Gene3D G3DSA:2.102.10.10 40 167 1.3E-21 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS19990 9192694ec1755a6cf8d247a5e815efba 170 Gene3D G3DSA:1.20.5.700 2 39 2.7E-16 T 29-03-2018 CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 27 53 - T 29-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 SUPERFAMILY SSF54909 69 156 4.29E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 Pfam PF01037 Lrp/AsnC ligand binding domain 79 147 2.6E-19 T 29-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 Gene3D G3DSA:1.10.10.10 3 58 1.0E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 SUPERFAMILY SSF46785 8 69 1.07E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 Gene3D G3DSA:3.30.70.920 61 157 2.5E-23 T 29-03-2018 CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 1.8E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 1.8E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 1.8E-13 T 29-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 SMART SM00344 9 118 6.0E-38 T 29-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CSW12_RS03490 fb3670f5afccc8fdf54311d8a4f5dfa1 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 1.2E-13 T 29-03-2018 CSW12_RS25475 3e162f3621902e7f561b36351ae7a61c 152 PRINTS PR00502 NUDIX hydrolase family signature 26 40 9.1E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS25475 3e162f3621902e7f561b36351ae7a61c 152 PRINTS PR00502 NUDIX hydrolase family signature 40 55 9.1E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS25475 3e162f3621902e7f561b36351ae7a61c 152 Gene3D G3DSA:3.90.79.10 1 152 1.7E-27 T 29-03-2018 CSW12_RS25475 3e162f3621902e7f561b36351ae7a61c 152 Pfam PF00293 NUDIX domain 4 124 1.5E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS25475 3e162f3621902e7f561b36351ae7a61c 152 SUPERFAMILY SSF55811 3 128 3.01E-29 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS26970 4268141fdb36305bc309317d8a3b4d1e 230 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 230 35.072 T 29-03-2018 IPR024891 Antiholin-like protein LrgB CSW12_RS26970 4268141fdb36305bc309317d8a3b4d1e 230 Pfam PF04172 LrgB-like family 14 227 5.1E-69 T 29-03-2018 IPR007300 CidB/LrgB family CSW12_RS09935 f38e574f19f4913d3b88d8b388ce903d 154 Pfam PF02391 MoaE protein 9 119 6.3E-38 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09935 f38e574f19f4913d3b88d8b388ce903d 154 Gene3D G3DSA:3.90.1170.40 2 145 1.5E-48 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS09935 f38e574f19f4913d3b88d8b388ce903d 154 SUPERFAMILY SSF54690 5 138 1.83E-46 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS03940 a9cde600ef90d6e09b4285f058b6ec20 245 SMART SM00422 3 72 6.3E-22 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03940 a9cde600ef90d6e09b4285f058b6ec20 245 SUPERFAMILY SSF46955 5 123 8.06E-26 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS03940 a9cde600ef90d6e09b4285f058b6ec20 245 Pfam PF13411 MerR HTH family regulatory protein 5 69 5.9E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS03940 a9cde600ef90d6e09b4285f058b6ec20 245 Gene3D G3DSA:1.10.1660.10 58 123 2.1E-5 T 29-03-2018 CSW12_RS03940 a9cde600ef90d6e09b4285f058b6ec20 245 Gene3D G3DSA:1.10.1660.10 1 57 8.1E-19 T 29-03-2018 CSW12_RS07005 922a921c0ab99fa50c504c5d19b060f7 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.9E-8 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CSW12_RS07005 922a921c0ab99fa50c504c5d19b060f7 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 2.9E-8 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CSW12_RS07005 922a921c0ab99fa50c504c5d19b060f7 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.9E-8 T 29-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CSW12_RS07005 922a921c0ab99fa50c504c5d19b060f7 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 3.8E-21 T 29-03-2018 CSW12_RS07005 922a921c0ab99fa50c504c5d19b060f7 82 Gene3D G3DSA:3.30.70.20 2 82 1.6E-9 T 29-03-2018 CSW12_RS07005 922a921c0ab99fa50c504c5d19b060f7 82 SUPERFAMILY SSF54862 4 72 1.82E-13 T 29-03-2018 CSW12_RS15600 6e0c2710e4f82f64dc905b325353dae7 269 Gene3D G3DSA:2.30.30.410 24 110 6.0E-8 T 29-03-2018 CSW12_RS15600 6e0c2710e4f82f64dc905b325353dae7 269 Pfam PF12385 Papain-like cysteine protease AvrRpt2 116 255 5.1E-38 T 29-03-2018 IPR022118 Peptidase C70, AvrRpt2 CSW12_RS15600 6e0c2710e4f82f64dc905b325353dae7 269 Gene3D G3DSA:3.90.70.10 111 266 7.5E-25 T 29-03-2018 CSW12_RS13510 9cbc96c5cd1267d4a323c6979be19252 345 Gene3D G3DSA:3.10.310.10 153 309 3.8E-53 T 29-03-2018 CSW12_RS13510 9cbc96c5cd1267d4a323c6979be19252 345 Gene3D G3DSA:3.10.310.10 1 152 2.5E-34 T 29-03-2018 CSW12_RS13510 9cbc96c5cd1267d4a323c6979be19252 345 PIRSF PIRSF029792 1 334 1.4E-143 T 29-03-2018 IPR008794 Proline racemase family CSW12_RS13510 9cbc96c5cd1267d4a323c6979be19252 345 SUPERFAMILY SSF54506 1 331 2.57E-113 T 29-03-2018 CSW12_RS13510 9cbc96c5cd1267d4a323c6979be19252 345 Pfam PF05544 Proline racemase 10 331 1.1E-118 T 29-03-2018 IPR008794 Proline racemase family CSW12_RS01170 2c762076b6ae48845e557cee103e0a78 185 Pfam PF13302 Acetyltransferase (GNAT) domain 7 132 9.0E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS01170 2c762076b6ae48845e557cee103e0a78 185 SUPERFAMILY SSF55729 3 156 5.31E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS01170 2c762076b6ae48845e557cee103e0a78 185 Gene3D G3DSA:3.40.630.30 30 170 2.0E-9 T 29-03-2018 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 SUPERFAMILY SSF143865 15 249 4.18E-57 T 29-03-2018 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 11 315 4.2E-87 T 29-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 Gene3D G3DSA:3.30.460.20 1 124 5.9E-25 T 29-03-2018 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 Pfam PF01544 CorA-like Mg2+ transporter protein 29 311 9.1E-74 T 29-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 Gene3D G3DSA:1.20.58.340 132 247 1.2E-23 T 29-03-2018 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 SUPERFAMILY SSF144083 251 312 5.23E-21 T 29-03-2018 CSW12_RS07250 2a589e60259cb1d181c440de3d3aeefd 316 Gene3D G3DSA:1.20.58.340 248 315 4.1E-21 T 29-03-2018 CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Gene3D G3DSA:2.130.10.10 368 500 2.0E-22 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Gene3D G3DSA:2.130.10.10 240 367 2.7E-19 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Gene3D G3DSA:2.130.10.10 501 542 0.0021 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 291 329 9.2E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 251 288 1.5E-9 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 374 413 1.8E-11 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 332 371 2.6E-10 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Pfam PF01391 Collagen triple helix repeat (20 copies) 191 243 2.1E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Pfam PF01391 Collagen triple helix repeat (20 copies) 151 206 1.1E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 SUPERFAMILY SSF51004 249 536 6.67E-53 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Gene3D G3DSA:2.160.20.50 196 239 2.4E-9 T 29-03-2018 CSW12_RS00405 6beb71c048be2ccece7ac13c387df753 543 Gene3D G3DSA:2.160.20.50 142 195 1.0E-7 T 29-03-2018 CSW12_RS18690 1be7c4e37a11f69c1dc192978f26420b 170 Gene3D G3DSA:3.40.630.30 10 159 3.3E-15 T 29-03-2018 CSW12_RS18690 1be7c4e37a11f69c1dc192978f26420b 170 Pfam PF13302 Acetyltransferase (GNAT) domain 34 147 1.1E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS18690 1be7c4e37a11f69c1dc192978f26420b 170 SUPERFAMILY SSF55729 8 154 3.3E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS26475 d958e9af61891ee10d51269cc76fef99 122 SMART SM00448 3 114 1.7E-32 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS26475 d958e9af61891ee10d51269cc76fef99 122 SUPERFAMILY SSF52172 4 118 1.99E-36 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS26475 d958e9af61891ee10d51269cc76fef99 122 Gene3D G3DSA:3.40.50.2300 2 121 2.0E-34 T 29-03-2018 CSW12_RS26475 d958e9af61891ee10d51269cc76fef99 122 Pfam PF00072 Response regulator receiver domain 5 115 3.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS24955 f7a35aea71892703362376aebfc80a1d 153 Gene3D G3DSA:2.40.440.10 21 153 1.3E-33 T 29-03-2018 CSW12_RS24955 f7a35aea71892703362376aebfc80a1d 153 Pfam PF03734 L,D-transpeptidase catalytic domain 31 152 2.5E-21 T 29-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CSW12_RS24955 f7a35aea71892703362376aebfc80a1d 153 SUPERFAMILY SSF141523 27 152 2.62E-30 T 29-03-2018 CSW12_RS14060 b8fe561bc03e0a9ac352c15a7e4dcca7 333 Gene3D G3DSA:3.40.50.1820 53 320 3.8E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS14060 b8fe561bc03e0a9ac352c15a7e4dcca7 333 SUPERFAMILY SSF53474 80 324 1.76E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS14060 b8fe561bc03e0a9ac352c15a7e4dcca7 333 Pfam PF09752 Abhydrolase domain containing 18 130 201 8.9E-5 T 29-03-2018 IPR019149 Abhydrolase domain containing 18 CSW12_RS19660 27f05ed3153eba0f4a4ae304aae18365 247 Pfam PF02706 Chain length determinant protein 4 92 2.3E-10 T 29-03-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 CSW12_RS19660 27f05ed3153eba0f4a4ae304aae18365 247 Gene3D G3DSA:3.30.1890.10 37 175 3.5E-4 T 29-03-2018 CSW12_RS17415 65a2563cb5863413805e18b379d95811 82 Pfam PF13780 Domain of unknown function (DUF4176) 3 73 6.9E-24 T 29-03-2018 IPR025233 Protein of unknown function DUF4176 CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 24 349 1.7E-71 T 29-03-2018 IPR017439 Amidohydrolase GO:0016787 CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 Gene3D G3DSA:3.40.630.10 7 401 9.0E-66 T 29-03-2018 CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 SUPERFAMILY SSF55031 178 283 3.84E-24 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 PIRSF PIRSF037226 3 401 1.6E-177 T 29-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 Pfam PF07687 Peptidase dimerisation domain 182 271 4.0E-9 T 29-03-2018 IPR011650 Peptidase M20, dimerisation domain CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 SUPERFAMILY SSF53187 290 384 3.97E-60 T 29-03-2018 CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 SUPERFAMILY SSF53187 11 190 3.97E-60 T 29-03-2018 CSW12_RS11945 9c59d424437e628ae233a669c5ee63d1 401 Pfam PF01546 Peptidase family M20/M25/M40 89 354 3.2E-9 T 29-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CSW12_RS03085 d5f0a47e907cb38525f5861c0e029029 71 Pfam PF07561 Domain of Unknown Function (DUF1540) 4 67 1.8E-13 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CSW12_RS23650 b257503c914f07c8fde3b8d5ee282709 373 Gene3D G3DSA:3.40.390.10 42 358 1.7E-12 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CSW12_RS07365 39e2c202765e8f1e997010d96532136b 288 Gene3D G3DSA:1.10.238.10 144 254 0.0016 T 29-03-2018 CSW12_RS07365 39e2c202765e8f1e997010d96532136b 288 Pfam PF06207 Protein of unknown function (DUF1002) 34 251 5.3E-79 T 29-03-2018 IPR009343 Protein of unknown function DUF1002 CSW12_RS15760 12668f88fe2cd6c7325c7ac894bfb1c5 519 Gene3D G3DSA:3.20.20.80 23 323 8.4E-43 T 29-03-2018 CSW12_RS15760 12668f88fe2cd6c7325c7ac894bfb1c5 519 SUPERFAMILY SSF51445 66 327 4.45E-24 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS15760 12668f88fe2cd6c7325c7ac894bfb1c5 519 Pfam PF02638 Glycosyl hydrolase-like 10 39 359 5.2E-107 T 29-03-2018 IPR003790 Glycosyl hydrolase-like 10 CSW12_RS15760 12668f88fe2cd6c7325c7ac894bfb1c5 519 Gene3D G3DSA:2.60.40.10 324 517 0.001 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS13170 3c325da3c82870f5811e4850cf7f5cd5 169 SUPERFAMILY SSF55144 4 151 1.73E-14 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CSW12_RS13170 3c325da3c82870f5811e4850cf7f5cd5 169 Gene3D G3DSA:3.90.1140.10 2 169 5.1E-15 T 29-03-2018 CSW12_RS13170 3c325da3c82870f5811e4850cf7f5cd5 169 Pfam PF13563 2'-5' RNA ligase superfamily 15 151 2.5E-16 T 29-03-2018 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 1.5E-18 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 SMART SM00418 10 89 3.5E-31 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 Gene3D G3DSA:1.10.10.10 2 88 1.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 34 52 - T 29-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 SUPERFAMILY SSF46785 6 85 5.12E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.3E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 32 43 2.3E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 2.3E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS11970 db8b3a70ba6f2940f54c351f0e01bc83 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.3E-19 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 SUPERFAMILY SSF52540 4 254 8.79E-65 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 Gene3D G3DSA:3.40.50.300 1 335 2.8E-77 T 29-03-2018 CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 Pfam PF00005 ABC transporter 25 182 1.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 SMART SM00382 33 232 3.5E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 2.5E-17 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.2E-23 T 29-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CSW12_RS28390 a425520a8ab47710d3fa38ae0a9d719c 336 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 SUPERFAMILY SSF110455 1 114 3.4E-36 T 29-03-2018 CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 Hamap MF_01469 Ribonuclease M5 [rnmV]. 2 178 31.899 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 Gene3D G3DSA:3.40.1360.20 1 124 6.0E-24 T 29-03-2018 CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 Pfam PF13331 Domain of unknown function (DUF4093) 93 175 5.0E-27 T 29-03-2018 IPR025156 Ribonuclease M5, C-terminal domain CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 Pfam PF13662 Toprim domain 4 70 2.4E-7 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 SMART SM00493 4 77 2.6E-7 T 29-03-2018 IPR006171 TOPRIM domain CSW12_RS27545 814d7fb757e276d12d30b44b4a249667 185 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 173 1.4E-64 T 29-03-2018 IPR004466 Ribonuclease M5 GO:0043822 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 5.8E-156 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 93 108 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 PRINTS PR00175 Sodium/alanine symporter signature 183 201 9.5E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 PRINTS PR00175 Sodium/alanine symporter signature 211 230 9.5E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 PRINTS PR00175 Sodium/alanine symporter signature 93 115 9.5E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 PRINTS PR00175 Sodium/alanine symporter signature 302 320 9.5E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 PRINTS PR00175 Sodium/alanine symporter signature 407 427 9.5E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 PRINTS PR00175 Sodium/alanine symporter signature 347 369 9.5E-61 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS25100 040f4c4c02fceec15c5088464e06a31e 476 Pfam PF01235 Sodium:alanine symporter family 56 450 1.1E-158 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS11140 59e3f965f97a6dcd4bed69d522c7aec6 180 SUPERFAMILY SSF160904 3 171 1.83E-30 T 29-03-2018 CSW12_RS11140 59e3f965f97a6dcd4bed69d522c7aec6 180 Pfam PF11706 CGNR zinc finger 124 172 1.1E-18 T 29-03-2018 IPR021005 Zinc finger, CGNR CSW12_RS11140 59e3f965f97a6dcd4bed69d522c7aec6 180 Gene3D G3DSA:1.10.3300.10 1 174 2.8E-26 T 29-03-2018 IPR023286 ABATE domain CSW12_RS12100 cec8df7158f44a9e11770a839285768d 341 SUPERFAMILY SSF53067 5 166 1.88E-7 T 29-03-2018 CSW12_RS12100 cec8df7158f44a9e11770a839285768d 341 Gene3D G3DSA:3.30.420.40 4 179 4.1E-16 T 29-03-2018 CSW12_RS18645 f52b7d4697a2cb2f9999d5e2da98a6cf 213 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 99 204 9.4E-10 T 29-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CSW12_RS18645 f52b7d4697a2cb2f9999d5e2da98a6cf 213 Pfam PF07299 Elongation factor G-binding protein, N-terminal 4 86 1.7E-27 T 29-03-2018 IPR010841 Elongation factor G-binding protein, N-terminal CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 SMART SM00347 43 139 5.3E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 Gene3D G3DSA:1.10.10.10 2 150 5.3E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 SUPERFAMILY SSF46785 19 149 7.68E-29 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 Pfam PF01047 MarR family 48 104 2.6E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 1.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 1.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 149 1.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS07265 78461ffe948e692da3b56cf570b88565 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 1.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS10110 83cd3602f8038feb33e6b589820cafa9 225 Pfam PF02308 MgtC family 12 138 1.6E-37 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS10110 83cd3602f8038feb33e6b589820cafa9 225 PRINTS PR01837 MgtC/SapB protein signature 94 118 5.2E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS10110 83cd3602f8038feb33e6b589820cafa9 225 PRINTS PR01837 MgtC/SapB protein signature 14 33 5.2E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS10110 83cd3602f8038feb33e6b589820cafa9 225 PRINTS PR01837 MgtC/SapB protein signature 67 89 5.2E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS10110 83cd3602f8038feb33e6b589820cafa9 225 PRINTS PR01837 MgtC/SapB protein signature 33 51 5.2E-48 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS01980 f77a21f9a4aa3c3f923bb26871ae9b75 38 Pfam PF13219 Protein of unknown function (DUF4027) 1 36 1.1E-22 T 29-03-2018 IPR025104 Protein of unknown function DUF4027 CSW12_RS27645 1d838c4d1ba32cd97a7dcdc6e28df551 119 Gene3D G3DSA:1.20.5.320 2 105 1.6E-4 T 29-03-2018 CSW12_RS27645 1d838c4d1ba32cd97a7dcdc6e28df551 119 Pfam PF04977 Septum formation initiator 44 118 2.3E-18 T 29-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CSW12_RS19450 0486ff294018bd2d856ade0c7c4be2c8 62 SUPERFAMILY SSF50182 3 61 5.11E-19 T 29-03-2018 IPR010920 LSM domain CSW12_RS19450 0486ff294018bd2d856ade0c7c4be2c8 62 Pfam PF17209 Hfq protein 4 61 1.7E-19 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS19450 0486ff294018bd2d856ade0c7c4be2c8 62 Gene3D G3DSA:2.30.30.100 2 62 3.2E-22 T 29-03-2018 CSW12_RS19450 0486ff294018bd2d856ade0c7c4be2c8 62 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 62 25.134 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS19450 0486ff294018bd2d856ade0c7c4be2c8 62 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 3 61 9.3E-22 T 29-03-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CSW12_RS08490 12735c161ce06f6a7e5033384d4a5747 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 8.7E-37 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CSW12_RS24125 088b0a55264b705e054683c187c8e0e6 407 Gene3D G3DSA:1.20.1250.20 204 392 1.6E-17 T 29-03-2018 CSW12_RS24125 088b0a55264b705e054683c187c8e0e6 407 SUPERFAMILY SSF103473 17 387 1.03E-32 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS24125 088b0a55264b705e054683c187c8e0e6 407 Gene3D G3DSA:1.20.1250.20 1 194 3.2E-12 T 29-03-2018 CSW12_RS24125 088b0a55264b705e054683c187c8e0e6 407 Pfam PF07690 Major Facilitator Superfamily 220 384 9.6E-13 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS28705 d95592253238e9a153de8361b9d6b4da 116 Gene3D G3DSA:2.30.30.110 1 116 2.3E-38 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CSW12_RS28705 d95592253238e9a153de8361b9d6b4da 116 SUPERFAMILY SSF50118 2 113 7.68E-41 T 29-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CSW12_RS28705 d95592253238e9a153de8361b9d6b4da 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 1.8E-32 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CSW12_RS28705 d95592253238e9a153de8361b9d6b4da 116 PIRSF PIRSF033490 1 113 5.9E-39 T 29-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CSW12_RS30870 f5752452ee0bf0498ee008f977fb2e34 334 SUPERFAMILY SSF46785 68 121 8.53E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30870 f5752452ee0bf0498ee008f977fb2e34 334 Gene3D G3DSA:1.10.10.10 34 312 2.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01945 49339a10201d63a5b772ff3786928c39 173 Pfam PF01872 RibD C-terminal domain 4 164 1.6E-20 T 29-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CSW12_RS01945 49339a10201d63a5b772ff3786928c39 173 Gene3D G3DSA:3.40.430.10 3 170 4.2E-37 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CSW12_RS01945 49339a10201d63a5b772ff3786928c39 173 SUPERFAMILY SSF53597 2 172 1.31E-37 T 29-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CSW12_RS02435 c31334e1b501b1e70182dd1e70397b3b 180 Gene3D G3DSA:1.10.443.10 4 170 7.3E-32 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS02435 c31334e1b501b1e70182dd1e70397b3b 180 Pfam PF00589 Phage integrase family 13 164 4.2E-24 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS02435 c31334e1b501b1e70182dd1e70397b3b 180 SUPERFAMILY SSF56349 8 178 4.41E-37 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS11235 86641a28f86dc97e264b5ed795a0719f 340 Pfam PF13350 Tyrosine phosphatase family 88 338 6.3E-66 T 29-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CSW12_RS11235 86641a28f86dc97e264b5ed795a0719f 340 Gene3D G3DSA:3.90.190.10 102 278 4.9E-21 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CSW12_RS11235 86641a28f86dc97e264b5ed795a0719f 340 SUPERFAMILY SSF52799 88 337 8.91E-55 T 29-03-2018 IPR029021 Protein-tyrosine phosphatase-like CSW12_RS05945 b08328ce8429abdc32aede1d713c8357 197 Pfam PF12389 Camelysin metallo-endopeptidase 2 196 1.2E-92 T 29-03-2018 IPR022121 Peptidase M73, camelysin CSW12_RS05945 b08328ce8429abdc32aede1d713c8357 197 Gene3D G3DSA:2.60.40.10 39 196 7.8E-4 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS05945 b08328ce8429abdc32aede1d713c8357 197 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 1.3E-12 T 29-03-2018 IPR023833 Signal peptide, camelysin CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 Pfam PF03466 LysR substrate binding domain 86 282 1.1E-38 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.9E-5 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 SUPERFAMILY SSF53850 88 282 1.01E-32 T 29-03-2018 CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 SUPERFAMILY SSF46785 1 101 2.13E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-20 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 Gene3D G3DSA:1.10.10.10 1 82 1.2E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 Gene3D G3DSA:3.40.190.10 159 253 2.4E-17 T 29-03-2018 CSW12_RS28470 1b99c40d8dddb35804ea0864173685b3 288 Gene3D G3DSA:3.40.190.10 88 158 2.4E-10 T 29-03-2018 CSW12_RS30750 cb2930a44ef257582a804a3a2128924b 185 Pfam PF13814 Replication-relaxation 21 147 1.2E-10 T 29-03-2018 IPR025855 Plasmid replication-relaxation CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 Pfam PF04389 Peptidase family M28 246 445 1.4E-38 T 29-03-2018 IPR007484 Peptidase M28 CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 Gene3D G3DSA:3.40.630.10 33 118 8.5E-5 T 29-03-2018 CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 Gene3D G3DSA:3.40.630.10 225 452 1.7E-36 T 29-03-2018 CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 Pfam PF02225 PA domain 130 219 3.7E-10 T 29-03-2018 IPR003137 PA domain CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 Gene3D G3DSA:3.50.30.30 119 224 1.7E-15 T 29-03-2018 CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 SUPERFAMILY SSF53187 39 98 6.99E-54 T 29-03-2018 CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 SUPERFAMILY SSF53187 238 452 6.99E-54 T 29-03-2018 CSW12_RS26585 0850eb52a1913b2304677e5397a26374 466 SUPERFAMILY SSF52025 127 227 8.5E-10 T 29-03-2018 CSW12_RS12715 3e936b2d51820f6ba8c30a05e66ac903 474 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS12715 3e936b2d51820f6ba8c30a05e66ac903 474 Pfam PF00324 Amino acid permease 19 461 2.2E-129 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS12715 3e936b2d51820f6ba8c30a05e66ac903 474 PIRSF PIRSF006060 1 474 5.5E-74 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 1.2E-51 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 Gene3D G3DSA:2.10.109.10 25 183 4.4E-43 T 29-03-2018 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 4.9E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 4.9E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 4.9E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 SUPERFAMILY SSF51306 27 182 1.09E-51 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 Pfam PF00717 Peptidase S24-like 36 103 2.0E-18 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS12285 d2ae478bed8f88dfb41632e2d5691ec4 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CSW12_RS00750 26683aadfc908bf03b80cab7058de2d1 263 Gene3D G3DSA:3.60.10.10 1 262 1.1E-35 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS00750 26683aadfc908bf03b80cab7058de2d1 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 254 5.1E-9 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS00750 26683aadfc908bf03b80cab7058de2d1 263 SUPERFAMILY SSF56219 1 261 1.83E-34 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS14850 f03c9754def94062dce97619adf5387d 315 SUPERFAMILY SSF56112 6 314 1.17E-52 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS14850 f03c9754def94062dce97619adf5387d 315 Pfam PF01636 Phosphotransferase enzyme family 28 224 6.4E-14 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS14850 f03c9754def94062dce97619adf5387d 315 Gene3D G3DSA:3.30.200.20 3 97 4.3E-12 T 29-03-2018 CSW12_RS14850 f03c9754def94062dce97619adf5387d 315 Gene3D G3DSA:3.90.1200.10 102 315 8.4E-21 T 29-03-2018 CSW12_RS09330 061ecefdc790b1bb9407e59a348ccb0b 267 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 15 267 1.0E-89 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CSW12_RS09330 061ecefdc790b1bb9407e59a348ccb0b 267 Gene3D G3DSA:1.10.3720.10 15 267 1.7E-32 T 29-03-2018 CSW12_RS09330 061ecefdc790b1bb9407e59a348ccb0b 267 SUPERFAMILY SSF161098 71 258 2.49E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS09330 061ecefdc790b1bb9407e59a348ccb0b 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 265 2.8E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS19725 f7c361e30094db03a11be43c9397f1c3 152 Gene3D G3DSA:3.40.630.30 1 152 1.8E-29 T 29-03-2018 CSW12_RS19725 f7c361e30094db03a11be43c9397f1c3 152 Pfam PF00583 Acetyltransferase (GNAT) family 33 116 3.0E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS19725 f7c361e30094db03a11be43c9397f1c3 152 SUPERFAMILY SSF55729 17 151 4.9E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13555 5ee87998b9fb41ee6837a4e52896e4b7 309 Pfam PF02833 DHHA2 domain 183 306 5.8E-22 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS13555 5ee87998b9fb41ee6837a4e52896e4b7 309 SUPERFAMILY SSF64182 1 307 9.03E-88 T 29-03-2018 CSW12_RS13555 5ee87998b9fb41ee6837a4e52896e4b7 309 Pfam PF01368 DHH family 3 146 1.1E-31 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS13555 5ee87998b9fb41ee6837a4e52896e4b7 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 46.708 T 29-03-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS13555 5ee87998b9fb41ee6837a4e52896e4b7 309 Gene3D G3DSA:3.90.1640.10 1 188 5.2E-72 T 29-03-2018 CSW12_RS13555 5ee87998b9fb41ee6837a4e52896e4b7 309 SMART SM01131 181 307 3.7E-54 T 29-03-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 SMART SM00287 46 107 6.9E-9 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 SMART SM00287 285 346 2.4E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 SMART SM00287 117 178 5.7E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 SMART SM00287 367 429 4.9E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 SMART SM00287 200 262 1.1E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 SUPERFAMILY SSF54001 458 576 4.66E-33 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Gene3D G3DSA:2.40.50.110 107 178 1.6E-16 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Gene3D G3DSA:2.40.50.110 26 106 2.4E-18 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Gene3D G3DSA:2.40.50.110 269 346 2.5E-17 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Gene3D G3DSA:2.40.50.110 348 428 1.7E-20 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Pfam PF00877 NlpC/P60 family 473 574 6.0E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Gene3D G3DSA:3.90.1720.10 449 577 4.2E-31 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Gene3D G3DSA:2.30.30.410 180 268 6.1E-19 T 29-03-2018 CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Pfam PF08239 Bacterial SH3 domain 208 258 1.4E-13 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Pfam PF08239 Bacterial SH3 domain 126 176 2.0E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Pfam PF08239 Bacterial SH3 domain 54 105 5.9E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Pfam PF08239 Bacterial SH3 domain 294 343 9.2E-12 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS25925 6e76c73e6702fbe3a6ab1206f50e2be1 578 Pfam PF08239 Bacterial SH3 domain 375 426 3.7E-14 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS29455 2372cce175feee6fc494d4ce68a872a7 253 SMART SM00382 35 234 2.0E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS29455 2372cce175feee6fc494d4ce68a872a7 253 SUPERFAMILY SSF52540 6 227 4.62E-66 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS29455 2372cce175feee6fc494d4ce68a872a7 253 Pfam PF00005 ABC transporter 26 174 4.6E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS29455 2372cce175feee6fc494d4ce68a872a7 253 Gene3D G3DSA:3.40.50.300 1 247 4.0E-64 T 29-03-2018 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 35.042 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 2.3E-132 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 SUPERFAMILY SSF56014 263 352 2.78E-14 T 29-03-2018 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 PIRSF PIRSF004640 1 365 2.0E-154 T 29-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 SUPERFAMILY SSF51717 15 214 2.28E-15 T 29-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 Pfam PF04551 GcpE protein 10 351 9.2E-141 T 29-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CSW12_RS21005 ec789b25312b7e191fa0834df0f679fa 370 Gene3D G3DSA:3.20.20.120 17 229 5.9E-23 T 29-03-2018 IPR029065 Enolase C-terminal domain-like CSW12_RS04640 a465b7f566aec7409c175cd8f2f88075 313 SUPERFAMILY SSF103481 45 145 1.57E-14 T 29-03-2018 CSW12_RS04640 a465b7f566aec7409c175cd8f2f88075 313 Pfam PF00892 EamA-like transporter family 158 289 3.4E-21 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS04640 a465b7f566aec7409c175cd8f2f88075 313 Pfam PF00892 EamA-like transporter family 14 143 3.1E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS04640 a465b7f566aec7409c175cd8f2f88075 313 SUPERFAMILY SSF103481 192 292 2.48E-12 T 29-03-2018 CSW12_RS26035 205dc4c2a7c7f87f9978bc890dc9d9e5 226 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS26035 205dc4c2a7c7f87f9978bc890dc9d9e5 226 Pfam PF00005 ABC transporter 21 169 1.5E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26035 205dc4c2a7c7f87f9978bc890dc9d9e5 226 SUPERFAMILY SSF52540 1 222 1.01E-75 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26035 205dc4c2a7c7f87f9978bc890dc9d9e5 226 Gene3D G3DSA:3.40.50.300 1 224 4.0E-64 T 29-03-2018 CSW12_RS26035 205dc4c2a7c7f87f9978bc890dc9d9e5 226 SMART SM00382 30 217 6.4E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS10010 e76427a2e9a207e9b62d0411dd93cb86 369 Pfam PF13354 Beta-lactamase enzyme family 60 303 8.3E-15 T 29-03-2018 CSW12_RS10010 e76427a2e9a207e9b62d0411dd93cb86 369 Gene3D G3DSA:3.40.710.10 33 357 1.1E-17 T 29-03-2018 CSW12_RS10010 e76427a2e9a207e9b62d0411dd93cb86 369 SUPERFAMILY SSF56601 42 184 2.51E-25 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS10010 e76427a2e9a207e9b62d0411dd93cb86 369 SUPERFAMILY SSF56601 244 350 2.51E-25 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 SMART SM00450 93 186 3.6E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 9 33 - T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 Pfam PF00581 Rhodanese-like domain 95 181 2.8E-13 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 Gene3D G3DSA:3.30.110.40 6 79 2.4E-25 T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 Gene3D G3DSA:3.40.250.10 80 186 1.5E-24 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 Pfam PF01206 Sulfurtransferase TusA 8 76 6.0E-21 T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 SUPERFAMILY SSF64307 2 76 5.89E-24 T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03220 cb08088d7983d4a4acb6340671faf6b6 186 SUPERFAMILY SSF52821 82 182 3.01E-28 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Gene3D G3DSA:2.130.10.10 257 336 5.4E-4 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Gene3D G3DSA:2.160.20.50 198 256 7.7E-10 T 29-03-2018 CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Gene3D G3DSA:2.160.20.50 144 197 3.4E-7 T 29-03-2018 CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 SUPERFAMILY SSF51004 251 531 8.37E-41 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 337 376 1.8E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 379 418 1.0E-7 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 467 506 1.2E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Gene3D G3DSA:2.130.10.10 433 552 5.9E-15 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Gene3D G3DSA:2.130.10.10 337 432 4.4E-17 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Pfam PF01391 Collagen triple helix repeat (20 copies) 198 245 2.2E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS02570 862ce015c54bfe07faf997b4a72ab3af 554 Pfam PF01391 Collagen triple helix repeat (20 copies) 153 208 3.0E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS27855 803b544bbf8a0fa39d7a328d3dba0ed0 226 SUPERFAMILY SSF53448 2 221 1.1E-61 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS27855 803b544bbf8a0fa39d7a328d3dba0ed0 226 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 220 5.5E-77 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CSW12_RS27855 803b544bbf8a0fa39d7a328d3dba0ed0 226 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 99 106 - T 29-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CSW12_RS27855 803b544bbf8a0fa39d7a328d3dba0ed0 226 Gene3D G3DSA:3.90.550.10 1 223 8.0E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS27855 803b544bbf8a0fa39d7a328d3dba0ed0 226 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 221 44.657 T 29-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CSW12_RS27855 803b544bbf8a0fa39d7a328d3dba0ed0 226 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 221 5.0E-78 T 29-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CSW12_RS03580 9826a6eb64713e1676871e743d034c03 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 29-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS03580 9826a6eb64713e1676871e743d034c03 479 Pfam PF00171 Aldehyde dehydrogenase family 15 472 1.5E-156 T 29-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS03580 9826a6eb64713e1676871e743d034c03 479 Gene3D G3DSA:3.40.605.10 1 272 2.3E-90 T 29-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CSW12_RS03580 9826a6eb64713e1676871e743d034c03 479 Gene3D G3DSA:3.40.309.10 273 459 2.8E-63 T 29-03-2018 CSW12_RS03580 9826a6eb64713e1676871e743d034c03 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 29-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CSW12_RS03580 9826a6eb64713e1676871e743d034c03 479 SUPERFAMILY SSF53720 5 476 1.31E-150 T 29-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CSW12_RS03550 88eea3b50f61c8ce4b9aa5ac11a23d28 171 Pfam PF01965 DJ-1/PfpI family 3 167 2.0E-51 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS03550 88eea3b50f61c8ce4b9aa5ac11a23d28 171 Gene3D G3DSA:3.40.50.880 1 171 4.0E-41 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS03550 88eea3b50f61c8ce4b9aa5ac11a23d28 171 SUPERFAMILY SSF52317 1 170 2.66E-45 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS03550 88eea3b50f61c8ce4b9aa5ac11a23d28 171 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 170 3.4E-56 T 29-03-2018 IPR006286 Peptidase C56, PfpI CSW12_RS14440 37c319540597d3354a014c403b4b2615 168 SUPERFAMILY SSF81301 7 166 3.6E-47 T 29-03-2018 CSW12_RS14440 37c319540597d3354a014c403b4b2615 168 Gene3D G3DSA:3.30.460.10 1 168 1.2E-50 T 29-03-2018 CSW12_RS14440 37c319540597d3354a014c403b4b2615 168 Pfam PF04229 GrpB protein 5 163 5.5E-45 T 29-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CSW12_RS17735 22921a31a6094491a4f0cfd5bd711664 219 Pfam PF13460 NAD(P)H-binding 10 125 8.4E-11 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS17735 22921a31a6094491a4f0cfd5bd711664 219 Gene3D G3DSA:3.40.50.720 1 219 1.5E-21 T 29-03-2018 CSW12_RS17735 22921a31a6094491a4f0cfd5bd711664 219 SUPERFAMILY SSF51735 1 206 1.03E-40 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS24675 c9b8b5246cd6367dc809a3dfcb678780 327 SUPERFAMILY SSF51261 112 314 2.04E-37 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS24675 c9b8b5246cd6367dc809a3dfcb678780 327 Gene3D G3DSA:1.10.530.10 26 180 0.0011 T 29-03-2018 CSW12_RS24675 c9b8b5246cd6367dc809a3dfcb678780 327 Pfam PF01551 Peptidase family M23 203 301 1.8E-19 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS24675 c9b8b5246cd6367dc809a3dfcb678780 327 Gene3D G3DSA:2.70.70.10 181 327 5.6E-25 T 29-03-2018 CSW12_RS02375 6cd53fbb4390757e9acb131b71389e23 62 SUPERFAMILY SSF47413 3 60 3.75E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02375 6cd53fbb4390757e9acb131b71389e23 62 SMART SM00530 4 59 1.9E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02375 6cd53fbb4390757e9acb131b71389e23 62 Pfam PF01381 Helix-turn-helix 8 59 2.3E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02375 6cd53fbb4390757e9acb131b71389e23 62 Gene3D G3DSA:1.10.260.40 1 62 3.2E-13 T 29-03-2018 CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 SUPERFAMILY SSF51004 252 539 5.49E-59 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Gene3D G3DSA:2.160.20.50 198 256 2.3E-9 T 29-03-2018 CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Gene3D G3DSA:2.160.20.50 144 197 3.5E-7 T 29-03-2018 CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 419 458 9.3E-10 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 253 290 3.0E-9 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 377 416 1.9E-11 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 503 542 8.0E-10 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 461 500 5.7E-12 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 293 332 3.4E-10 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 335 374 3.0E-8 T 29-03-2018 IPR011964 YVTN beta-propeller repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Gene3D G3DSA:2.130.10.10 257 336 2.8E-11 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Gene3D G3DSA:2.130.10.10 454 545 1.1E-15 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Gene3D G3DSA:2.130.10.10 337 453 1.9E-21 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Pfam PF01391 Collagen triple helix repeat (20 copies) 153 206 2.6E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS02285 3cc2a5885b7efd4e8d82d4abfc62cb8e 546 Pfam PF01391 Collagen triple helix repeat (20 copies) 196 245 4.9E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS14785 f9bbc80594b9acad2125a4934962581e 210 Gene3D G3DSA:3.40.50.880 1 210 4.2E-23 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS14785 f9bbc80594b9acad2125a4934962581e 210 Pfam PF01965 DJ-1/PfpI family 4 176 2.8E-31 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS14785 f9bbc80594b9acad2125a4934962581e 210 SUPERFAMILY SSF52317 4 178 4.97E-30 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS09190 4cdd674cdac3659253569e6ea93c7ea5 180 Gene3D G3DSA:1.20.120.80 7 178 1.3E-7 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS09190 4cdd674cdac3659253569e6ea93c7ea5 180 Pfam PF04238 Protein of unknown function (DUF420) 47 175 3.4E-43 T 29-03-2018 IPR007352 Protein of unknown function DUF420 CSW12_RS06100 22ddc5c858b7c359f5dd81618d03384c 147 SUPERFAMILY SSF54637 15 144 7.9E-40 T 29-03-2018 IPR029069 HotDog domain CSW12_RS06100 22ddc5c858b7c359f5dd81618d03384c 147 Pfam PF01575 MaoC like domain 25 127 1.8E-25 T 29-03-2018 IPR002539 MaoC-like domain CSW12_RS06100 22ddc5c858b7c359f5dd81618d03384c 147 Gene3D G3DSA:3.10.129.10 13 145 1.6E-37 T 29-03-2018 CSW12_RS05095 e9b8b8d455ee18a6ff75f8ffab2c0de2 144 Pfam PF05037 Protein of unknown function (DUF669) 2 131 6.5E-43 T 29-03-2018 IPR007731 Protein of unknown function DUF669 CSW12_RS10905 042e65de69fd22c3291dad9699022c81 338 Pfam PF00082 Subtilase family 7 248 1.5E-21 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS10905 042e65de69fd22c3291dad9699022c81 338 SUPERFAMILY SSF52743 6 244 7.86E-34 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS10905 042e65de69fd22c3291dad9699022c81 338 Gene3D G3DSA:3.40.50.200 2 278 4.0E-29 T 29-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CSW12_RS10905 042e65de69fd22c3291dad9699022c81 338 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 205 215 - T 29-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CSW12_RS28955 844560bffd72b4075d12521d4f7b634d 290 Gene3D G3DSA:3.40.50.150 46 241 2.9E-23 T 29-03-2018 CSW12_RS28955 844560bffd72b4075d12521d4f7b634d 290 SUPERFAMILY SSF53335 70 232 5.58E-25 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS28955 844560bffd72b4075d12521d4f7b634d 290 Pfam PF08241 Methyltransferase domain 89 185 1.7E-14 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS10665 81752b78a81e9806fdc2d11db9d827d8 154 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 135 5.8E-26 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CSW12_RS23950 d40c510ace50b9c573eb18f9cd87a0e0 338 SUPERFAMILY SSF53613 1 328 3.43E-62 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS23950 d40c510ace50b9c573eb18f9cd87a0e0 338 Gene3D G3DSA:3.40.1190.20 2 336 3.3E-42 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS23950 d40c510ace50b9c573eb18f9cd87a0e0 338 Pfam PF00294 pfkB family carbohydrate kinase 3 317 4.2E-32 T 29-03-2018 IPR011611 Carbohydrate kinase PfkB CSW12_RS10585 94517ada10e57444b690d00ccefff5e3 75 Pfam PF01166 TSC-22/dip/bun family 9 42 1.6E-6 T 29-03-2018 IPR000580 TSC-22 / Dip / Bun GO:0003700|GO:0006355 CSW12_RS10585 94517ada10e57444b690d00ccefff5e3 75 Gene3D G3DSA:1.20.5.490 9 39 4.3E-7 T 29-03-2018 CSW12_RS10585 94517ada10e57444b690d00ccefff5e3 75 SUPERFAMILY SSF58026 9 40 3.4E-5 T 29-03-2018 CSW12_RS08305 1f50a0cb782761d04494ee0468db4632 441 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 27 423 1.7E-135 T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CSW12_RS08305 1f50a0cb782761d04494ee0468db4632 441 Pfam PF00860 Permease family 27 400 1.9E-111 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS08305 1f50a0cb782761d04494ee0468db4632 441 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 346 366 - T 29-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 435 7.9E-19 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 SUPERFAMILY SSF55874 283 435 1.31E-32 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 Gene3D G3DSA:3.30.565.10 276 437 1.4E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 3.6E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS30820 2672f559ff66e0e680d29bc472d4ca85 458 SMART SM00387 328 437 7.6E-26 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS28370 2edc9970ef008b6924fc647adee52fad 167 Gene3D G3DSA:3.40.190.10 1 167 0.0012 T 29-03-2018 CSW12_RS06095 0f763ae0de64b66598b7ff44570b517f 61 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 1.8E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS06095 0f763ae0de64b66598b7ff44570b517f 61 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS06095 0f763ae0de64b66598b7ff44570b517f 61 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS26195 cf059f1e39ad5a2d9008db44a13cfe7a 280 SMART SM00382 29 216 2.4E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26195 cf059f1e39ad5a2d9008db44a13cfe7a 280 SUPERFAMILY SSF52540 4 219 2.46E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26195 cf059f1e39ad5a2d9008db44a13cfe7a 280 Pfam PF00005 ABC transporter 20 160 3.4E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26195 cf059f1e39ad5a2d9008db44a13cfe7a 280 Gene3D G3DSA:3.40.50.300 1 265 4.1E-67 T 29-03-2018 CSW12_RS26195 cf059f1e39ad5a2d9008db44a13cfe7a 280 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS22605 e0d67d68c94b0799358ade0ad6cd7c47 153 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 6.0E-44 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CSW12_RS22605 e0d67d68c94b0799358ade0ad6cd7c47 153 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 19.171 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CSW12_RS22605 e0d67d68c94b0799358ade0ad6cd7c47 153 Pfam PF04284 Protein of unknown function (DUF441) 7 146 2.1E-48 T 29-03-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame CSW12_RS23295 c7d4409ae6c85921cacbbe2145f1ef0b 171 Gene3D G3DSA:3.40.50.300 2 171 6.3E-24 T 29-03-2018 CSW12_RS23295 c7d4409ae6c85921cacbbe2145f1ef0b 171 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 7 137 2.2E-34 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CSW12_RS23295 c7d4409ae6c85921cacbbe2145f1ef0b 171 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 7 138 4.2E-31 T 29-03-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CSW12_RS23295 c7d4409ae6c85921cacbbe2145f1ef0b 171 SUPERFAMILY SSF52540 6 137 4.96E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS04520 870a0666e83a1f88f6d26e3864d9fae9 111 ProDom PD073069 YHAI 3D-STRUCTURE 11 100 1.0E-44 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CSW12_RS04520 870a0666e83a1f88f6d26e3864d9fae9 111 SUPERFAMILY SSF109915 1 110 1.7E-48 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CSW12_RS04520 870a0666e83a1f88f6d26e3864d9fae9 111 Gene3D G3DSA:1.10.3750.10 2 107 5.4E-33 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CSW12_RS04520 870a0666e83a1f88f6d26e3864d9fae9 111 Pfam PF08963 Protein of unknown function (DUF1878) 2 108 3.2E-43 T 29-03-2018 IPR015058 Protein of unknown function DUF1878 CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 SUPERFAMILY SSF53383 17 362 2.66E-102 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 Gene3D G3DSA:3.90.1150.10 248 277 1.1E-5 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 Gene3D G3DSA:3.90.1150.10 278 369 1.7E-26 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 PIRSF PIRSF001434 1 365 8.2E-123 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 362 7.3E-133 T 29-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CSW12_RS20890 d16b03e4e888100758e62f3cb819484f 370 Gene3D G3DSA:3.40.640.10 2 246 3.8E-58 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS07040 b1fc14be8b1ce43d1bb24bbcf3e978df 202 PIRSF PIRSF029008 1 197 1.5E-63 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS07040 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 101 191 7.7E-14 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS07040 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 89 6.0E-27 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS07040 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Hamap MF_01124 Adapter protein MecA [mecA]. 1 195 24.584 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS07040 b1fc14be8b1ce43d1bb24bbcf3e978df 202 Gene3D G3DSA:3.40.47.10 20 187 0.0015 T 29-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CSW12_RS28965 b50ef1848fd65b472497e25fb1d220b7 264 Pfam PF03567 Sulfotransferase family 94 259 3.7E-8 T 29-03-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 CSW12_RS23365 e5a62107652d02284f315336219966ca 359 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 197 356 7.6E-28 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS23365 e5a62107652d02284f315336219966ca 359 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 358 1.3E-93 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 290 308 3.2E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 132 3.2E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 3.2E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 3.2E-16 T 29-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 SUPERFAMILY SSF51905 3 268 4.96E-42 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 Gene3D G3DSA:3.50.50.60 2 154 5.8E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 Gene3D G3DSA:3.40.50.720 161 326 3.5E-25 T 29-03-2018 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 294 1.3E-101 T 29-03-2018 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.3E-14 T 29-03-2018 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 9.3E-14 T 29-03-2018 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 9.3E-14 T 29-03-2018 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 9.3E-14 T 29-03-2018 CSW12_RS07065 6003cfe04f93a7ad2d90a1e785bc339c 326 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 323 9.3E-140 T 29-03-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA CSW12_RS07030 b4d1cf9e4d912e085d4ef47670c56c77 258 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 49 207 6.8E-10 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CSW12_RS07030 b4d1cf9e4d912e085d4ef47670c56c77 258 SUPERFAMILY SSF56300 45 257 1.97E-28 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS07030 b4d1cf9e4d912e085d4ef47670c56c77 258 Gene3D G3DSA:3.60.21.10 23 253 1.7E-21 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS11645 1b9e6be605c35c3cf2ba6fc1b9fd69cd 207 SMART SM00418 11 126 0.0016 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS11645 1b9e6be605c35c3cf2ba6fc1b9fd69cd 207 SUPERFAMILY SSF46785 3 160 1.32E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11645 1b9e6be605c35c3cf2ba6fc1b9fd69cd 207 Pfam PF12840 Helix-turn-helix domain 12 65 3.4E-8 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11645 1b9e6be605c35c3cf2ba6fc1b9fd69cd 207 Gene3D G3DSA:1.10.10.10 9 201 3.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16020 07003aabc75970079b951bb401621e84 135 SUPERFAMILY SSF55729 9 129 3.43E-20 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS16020 07003aabc75970079b951bb401621e84 135 Gene3D G3DSA:3.40.630.30 4 132 4.9E-16 T 29-03-2018 CSW12_RS16020 07003aabc75970079b951bb401621e84 135 Pfam PF13673 Acetyltransferase (GNAT) domain 35 125 6.7E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS03720 3640d57f00018093b4bc02765699e43d 495 Gene3D G3DSA:3.20.20.70 43 478 1.0E-41 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS03720 3640d57f00018093b4bc02765699e43d 495 SUPERFAMILY SSF102114 163 477 6.15E-70 T 29-03-2018 CSW12_RS03720 3640d57f00018093b4bc02765699e43d 495 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 89 489 3.5E-148 T 29-03-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ CSW12_RS03720 3640d57f00018093b4bc02765699e43d 495 Pfam PF04055 Radical SAM superfamily 178 350 1.4E-16 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS03720 3640d57f00018093b4bc02765699e43d 495 SMART SM00729 170 394 1.9E-46 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS10965 8bc2a219777244094a6047b1002b48b2 587 Pfam PF00916 Sulfate permease family 17 381 1.8E-92 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS10965 8bc2a219777244094a6047b1002b48b2 587 SUPERFAMILY SSF52091 438 544 1.53E-18 T 29-03-2018 IPR002645 STAS domain CSW12_RS10965 8bc2a219777244094a6047b1002b48b2 587 Gene3D G3DSA:3.30.750.24 431 553 2.3E-23 T 29-03-2018 IPR002645 STAS domain CSW12_RS10965 8bc2a219777244094a6047b1002b48b2 587 TIGRFAM TIGR00815 sulP: sulfate permease 9 540 2.6E-119 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 CSW12_RS10965 8bc2a219777244094a6047b1002b48b2 587 Pfam PF01740 STAS domain 441 541 5.3E-20 T 29-03-2018 IPR002645 STAS domain CSW12_RS10070 1050ea23b26854a342f4fd89f8aff6d3 281 Gene3D G3DSA:3.30.420.10 2 154 1.4E-20 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS10070 1050ea23b26854a342f4fd89f8aff6d3 281 SUPERFAMILY SSF53098 5 179 5.48E-29 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS10070 1050ea23b26854a342f4fd89f8aff6d3 281 SMART SM00479 6 183 3.2E-19 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS10070 1050ea23b26854a342f4fd89f8aff6d3 281 Pfam PF00929 Exonuclease 23 174 2.2E-22 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS10070 1050ea23b26854a342f4fd89f8aff6d3 281 Gene3D G3DSA:1.20.5.140 159 179 2.1E-5 T 29-03-2018 CSW12_RS30275 fc685304fed18657080723e42b7f918f 264 SUPERFAMILY SSF56399 5 261 4.8E-45 T 29-03-2018 CSW12_RS30275 fc685304fed18657080723e42b7f918f 264 Pfam PF03496 ADP-ribosyltransferase exoenzyme 50 258 1.1E-44 T 29-03-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 CSW12_RS30275 fc685304fed18657080723e42b7f918f 264 Gene3D G3DSA:3.90.176.10 33 263 6.9E-46 T 29-03-2018 CSW12_RS19445 21961e6b8c8a31dc9822fb96a7a0ce79 200 Gene3D G3DSA:1.10.3210.10 1 189 1.6E-38 T 29-03-2018 CSW12_RS19445 21961e6b8c8a31dc9822fb96a7a0ce79 200 Pfam PF13023 HD domain 12 169 4.9E-48 T 29-03-2018 IPR006674 HD domain CSW12_RS19445 21961e6b8c8a31dc9822fb96a7a0ce79 200 SUPERFAMILY SSF109604 3 175 4.4E-36 T 29-03-2018 CSW12_RS00980 5be5f0eda91687c8a586ccc37f5ddc4f 197 Pfam PF09335 SNARE associated Golgi protein 30 156 3.9E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS10990 6f6f4fb7abff64e45b99640ce9d67999 171 PIRSF PIRSF008757 13 171 1.8E-61 T 29-03-2018 IPR010371 Uncharacterised protein family UPF0303 CSW12_RS10990 6f6f4fb7abff64e45b99640ce9d67999 171 SUPERFAMILY SSF143744 30 169 5.36E-26 T 29-03-2018 CSW12_RS10990 6f6f4fb7abff64e45b99640ce9d67999 171 Pfam PF03928 Haem-degrading 38 165 2.1E-29 T 29-03-2018 IPR005624 Haem-degrading CSW12_RS10990 6f6f4fb7abff64e45b99640ce9d67999 171 Hamap MF_00761 UPF0303 protein . 16 171 33.976 T 29-03-2018 IPR010371 Uncharacterised protein family UPF0303 CSW12_RS24480 fcc2607e2d75ba2bea220700eb1e423c 117 Gene3D G3DSA:2.60.300.12 1 110 3.2E-36 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS24480 fcc2607e2d75ba2bea220700eb1e423c 117 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 102 5.6E-19 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS24480 fcc2607e2d75ba2bea220700eb1e423c 117 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 106 1.4E-34 T 29-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CSW12_RS24480 fcc2607e2d75ba2bea220700eb1e423c 117 SUPERFAMILY SSF89360 1 95 8.04E-26 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS24480 fcc2607e2d75ba2bea220700eb1e423c 117 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 29-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CSW12_RS12700 85ced1f4b1d8eb26c7a1c1562e211b4c 155 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 128 4.2E-7 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS12700 85ced1f4b1d8eb26c7a1c1562e211b4c 155 Gene3D G3DSA:3.10.180.10 4 155 9.6E-19 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12700 85ced1f4b1d8eb26c7a1c1562e211b4c 155 SUPERFAMILY SSF54593 6 138 2.28E-17 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS07210 146f1c37c60ff1d9e3c44e518c2a7673 215 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 206 2.0E-81 T 29-03-2018 IPR014196 Stage II sporulation protein M CSW12_RS07210 146f1c37c60ff1d9e3c44e518c2a7673 215 PIRSF PIRSF038973 2 213 1.3E-70 T 29-03-2018 IPR014196 Stage II sporulation protein M CSW12_RS07210 146f1c37c60ff1d9e3c44e518c2a7673 215 Pfam PF01944 Stage II sporulation protein M 26 202 2.1E-21 T 29-03-2018 IPR002798 Stage II sporulation protein M-like CSW12_RS13895 11af0a08d920fd302e86133a33455205 203 Gene3D G3DSA:1.10.357.10 68 203 9.4E-13 T 29-03-2018 CSW12_RS13895 11af0a08d920fd302e86133a33455205 203 SUPERFAMILY SSF46689 8 77 1.54E-14 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS13895 11af0a08d920fd302e86133a33455205 203 Gene3D G3DSA:1.10.10.60 10 67 2.9E-11 T 29-03-2018 CSW12_RS13895 11af0a08d920fd302e86133a33455205 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 63 1.4E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS13895 11af0a08d920fd302e86133a33455205 203 Pfam PF08359 YsiA-like protein, C-terminal region 70 196 2.7E-4 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CSW12_RS13895 11af0a08d920fd302e86133a33455205 203 SUPERFAMILY SSF48498 88 202 1.5E-28 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Gene3D G3DSA:2.30.30.410 541 620 2.0E-5 T 29-03-2018 CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Pfam PF00395 S-layer homology domain 147 187 3.4E-7 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Pfam PF00395 S-layer homology domain 84 126 2.9E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Pfam PF00395 S-layer homology domain 30 69 1.0E-7 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Gene3D G3DSA:2.40.50.110 272 321 0.027 T 29-03-2018 CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Gene3D G3DSA:1.10.530.10 407 540 7.6E-25 T 29-03-2018 CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 425 539 7.4E-16 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CSW12_RS03755 a52b0fc1b44d01b6c869d2e47e858889 620 SMART SM00047 411 549 1.4E-4 T 29-03-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 SUPERFAMILY SSF103473 10 413 6.15E-38 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 Pfam PF05977 Transmembrane secretion effector 28 428 6.1E-24 T 29-03-2018 IPR010290 Transmembrane secretion effector CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 PRINTS PR01988 Putative bacilysin exporter bacE signature 59 77 3.6E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 PRINTS PR01988 Putative bacilysin exporter bacE signature 178 195 3.6E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 PRINTS PR01988 Putative bacilysin exporter bacE signature 370 393 3.6E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 PRINTS PR01988 Putative bacilysin exporter bacE signature 151 172 3.6E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 Gene3D G3DSA:1.20.1250.20 7 204 5.6E-17 T 29-03-2018 CSW12_RS14375 ed6328c809ed7c40f1f67eabb4496690 431 Gene3D G3DSA:1.20.1250.20 220 416 2.9E-14 T 29-03-2018 CSW12_RS17830 2bc2c1d5a1be526dc782ca990e660954 115 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 3 105 4.0E-53 T 29-03-2018 CSW12_RS17830 2bc2c1d5a1be526dc782ca990e660954 115 Pfam PF14074 Protein of unknown function (DUF4257) 6 86 3.4E-32 T 29-03-2018 IPR025353 Protein of unknown function DUF4257) CSW12_RS14405 4cfadc576c7c7e9ba282b829e712ea62 151 ProDom PD093362 MEMBRANE UNCHARACTERIZED YXJN HOMOLOG B.SUBTILIS PROTEIN TRANSMEMBRANE 1 151 7.0E-47 T 29-03-2018 IPR020223 Uncharacterised protein YxjN CSW12_RS14405 4cfadc576c7c7e9ba282b829e712ea62 151 Pfam PF07301 Protein of unknown function (DUF1453) 5 146 3.2E-7 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 SUPERFAMILY SSF51338 3 55 5.81E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 SUPERFAMILY SSF51338 335 371 5.81E-21 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 Gene3D G3DSA:2.30.40.10 315 375 2.1E-11 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 Gene3D G3DSA:2.30.40.10 2 69 2.8E-14 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 Pfam PF01979 Amidohydrolase family 52 368 3.0E-19 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 SUPERFAMILY SSF51556 54 336 9.08E-43 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS01175 f64987fcc5aee8ef397e53dd4fb75f10 376 Gene3D G3DSA:3.20.20.140 70 314 3.0E-22 T 29-03-2018 CSW12_RS23350 585999a62bd0a33e984776dbf29aad19 374 Pfam PF00561 alpha/beta hydrolase fold 40 326 7.3E-12 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS23350 585999a62bd0a33e984776dbf29aad19 374 PIRSF PIRSF000443 1 374 2.5E-122 T 29-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CSW12_RS23350 585999a62bd0a33e984776dbf29aad19 374 SUPERFAMILY SSF53474 4 368 2.92E-69 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS23350 585999a62bd0a33e984776dbf29aad19 374 Gene3D G3DSA:3.40.50.1820 23 370 5.3E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS09395 eee0849dfb2aee3dca622a1a86842763 225 Pfam PF04172 LrgB-like family 10 222 1.5E-69 T 29-03-2018 IPR007300 CidB/LrgB family CSW12_RS11665 91fc212b384b5ca392803e5f23d4da70 193 Gene3D G3DSA:3.40.50.300 1 191 2.1E-10 T 29-03-2018 CSW12_RS11665 91fc212b384b5ca392803e5f23d4da70 193 SUPERFAMILY SSF52540 2 185 8.58E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11665 91fc212b384b5ca392803e5f23d4da70 193 Pfam PF13671 AAA domain 5 121 3.2E-9 T 29-03-2018 CSW12_RS22900 eb5f3687a430c144d64420bba9aee950 314 SUPERFAMILY SSF103481 196 301 6.93E-6 T 29-03-2018 CSW12_RS22900 eb5f3687a430c144d64420bba9aee950 314 Pfam PF00892 EamA-like transporter family 162 297 2.8E-12 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS22900 eb5f3687a430c144d64420bba9aee950 314 Pfam PF00892 EamA-like transporter family 8 145 9.5E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS22900 eb5f3687a430c144d64420bba9aee950 314 SUPERFAMILY SSF103481 48 148 7.45E-8 T 29-03-2018 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 Pfam PF04542 Sigma-70 region 2 18 81 3.6E-13 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 Pfam PF08281 Sigma-70, region 4 114 164 2.2E-14 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 Gene3D G3DSA:1.10.10.10 98 173 2.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 SUPERFAMILY SSF88659 106 169 4.14E-14 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 167 8.4E-31 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 SUPERFAMILY SSF88946 10 91 3.92E-19 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 Gene3D G3DSA:1.10.1740.10 4 86 3.5E-18 T 29-03-2018 CSW12_RS11770 af1d278498bcafefd7965ab0faa7f28e 177 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 39 70 - T 29-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS25515 b23c21a51b83d85174c59763bab403df 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 111 3.8E-25 T 29-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CSW12_RS02965 9ba320e94322fe439683ebaf54e19ea8 333 Gene3D G3DSA:3.40.190.10 32 134 4.1E-16 T 29-03-2018 CSW12_RS02965 9ba320e94322fe439683ebaf54e19ea8 333 Pfam PF09084 NMT1/THI5 like 44 259 2.5E-78 T 29-03-2018 IPR015168 SsuA/THI5-like CSW12_RS02965 9ba320e94322fe439683ebaf54e19ea8 333 Gene3D G3DSA:3.40.190.10 135 333 5.5E-25 T 29-03-2018 CSW12_RS02965 9ba320e94322fe439683ebaf54e19ea8 333 SUPERFAMILY SSF53850 34 260 3.42E-39 T 29-03-2018 CSW12_RS10465 b1641d4f5fa8f5dbfa9562da28939487 325 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 45 298 1.5E-27 T 29-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CSW12_RS10465 b1641d4f5fa8f5dbfa9562da28939487 325 Gene3D G3DSA:3.75.10.10 25 308 1.0E-43 T 29-03-2018 CSW12_RS10465 b1641d4f5fa8f5dbfa9562da28939487 325 SUPERFAMILY SSF55909 38 298 3.93E-48 T 29-03-2018 CSW12_RS03560 a97fda3cf3bfbeb3761d5246ad4e96de 399 PIRSF PIRSF037259 1 397 7.3E-121 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CSW12_RS03560 a97fda3cf3bfbeb3761d5246ad4e96de 399 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 380 2.2E-104 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CSW12_RS17065 5923e4edae4aaf5bf33f42ddd4a94009 367 Pfam PF07786 Protein of unknown function (DUF1624) 12 215 3.7E-18 T 29-03-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-6798695 CSW12_RS27125 1fc7e270ee0cb97ef9d0c66fbf1fc853 604 Pfam PF01432 Peptidase family M3 212 589 1.2E-38 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CSW12_RS27125 1fc7e270ee0cb97ef9d0c66fbf1fc853 604 Pfam PF08439 Oligopeptidase F 118 187 1.0E-20 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CSW12_RS27125 1fc7e270ee0cb97ef9d0c66fbf1fc853 604 SUPERFAMILY SSF55486 11 584 1.21E-108 T 29-03-2018 CSW12_RS27125 1fc7e270ee0cb97ef9d0c66fbf1fc853 604 Gene3D G3DSA:1.10.1370.10 82 588 5.0E-27 T 29-03-2018 CSW12_RS27125 1fc7e270ee0cb97ef9d0c66fbf1fc853 604 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 11 601 1.2E-225 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CSW12_RS20215 61b1cb4bb4554a5a27e08f7ddb837247 62 Pfam PF14164 YqzH-like protein 1 60 4.7E-23 T 29-03-2018 IPR025546 YqzH-like protein CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.3E-17 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 SUPERFAMILY SSF48498 78 189 7.51E-26 T 29-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 Gene3D G3DSA:1.10.357.10 68 192 5.2E-15 T 29-03-2018 CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.0E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 Gene3D G3DSA:1.10.10.60 46 67 8.9E-11 T 29-03-2018 CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 Gene3D G3DSA:1.10.10.60 2 45 7.7E-15 T 29-03-2018 CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 Pfam PF08359 YsiA-like protein, C-terminal region 58 189 1.9E-61 T 29-03-2018 IPR013570 Transcription regulator YsiA, C-terminal CSW12_RS22220 8efe031aa2ef0ee16c97fea5fa81060e 195 SUPERFAMILY SSF46689 5 80 1.64E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS22520 acff3b8507ee703139e8946486aac255 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 86.645 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CSW12_RS22520 acff3b8507ee703139e8946486aac255 153 Pfam PF03477 ATP cone domain 50 136 1.8E-20 T 29-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CSW12_RS22520 acff3b8507ee703139e8946486aac255 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 1.0E-67 T 29-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CSW12_RS25795 26549611278b12ddd95e513b049e0ac4 105 SUPERFAMILY SSF46973 2 100 2.22E-38 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS25795 26549611278b12ddd95e513b049e0ac4 105 Gene3D G3DSA:1.20.58.80 2 100 3.9E-40 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS25795 26549611278b12ddd95e513b049e0ac4 105 PIRSF PIRSF000699 1 105 3.3E-40 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS25795 26549611278b12ddd95e513b049e0ac4 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 99 1.3E-39 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS00805 5a8f401ed604da78b0a01c0fd1aecf10 332 Gene3D G3DSA:3.40.190.10 32 175 1.1E-21 T 29-03-2018 CSW12_RS00805 5a8f401ed604da78b0a01c0fd1aecf10 332 Gene3D G3DSA:3.40.190.10 179 331 3.0E-21 T 29-03-2018 CSW12_RS00805 5a8f401ed604da78b0a01c0fd1aecf10 332 Pfam PF09084 NMT1/THI5 like 44 258 6.9E-78 T 29-03-2018 IPR015168 SsuA/THI5-like CSW12_RS00805 5a8f401ed604da78b0a01c0fd1aecf10 332 SUPERFAMILY SSF53850 37 320 1.18E-44 T 29-03-2018 CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 Gene3D G3DSA:1.10.10.10 129 228 6.4E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 SMART SM00448 3 113 1.0E-41 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 Pfam PF00072 Response regulator receiver domain 5 112 3.5E-29 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 225 2.8E-25 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 Gene3D G3DSA:3.40.50.2300 2 128 8.7E-38 T 29-03-2018 CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 SUPERFAMILY SSF52172 3 179 5.73E-41 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS23795 d4e33af70ecbdb91d82f64b9b80c69d0 229 SMART SM00862 152 225 1.7E-23 T 29-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CSW12_RS05545 e84e1b90b6f607b85934c4f2b6b727a2 265 Gene3D G3DSA:2.60.200.30 123 239 4.2E-23 T 29-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CSW12_RS05545 e84e1b90b6f607b85934c4f2b6b727a2 265 Hamap MF_00361 NAD kinase [nadK]. 1 263 24.717 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CSW12_RS05545 e84e1b90b6f607b85934c4f2b6b727a2 265 Pfam PF01513 ATP-NAD kinase 31 188 1.8E-25 T 29-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CSW12_RS05545 e84e1b90b6f607b85934c4f2b6b727a2 265 Gene3D G3DSA:3.40.50.10330 1 122 7.9E-26 T 29-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CSW12_RS05545 e84e1b90b6f607b85934c4f2b6b727a2 265 SUPERFAMILY SSF111331 7 261 2.62E-64 T 29-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CSW12_RS19560 4dc42f7f1654f630f7b0ebdd466c6fd1 242 Pfam PF08892 YqcI/YcgG family 29 236 3.9E-71 T 29-03-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG CSW12_RS21000 fe463f8421604e8b613cf072955509e9 121 Gene3D G3DSA:3.10.350.10 59 121 7.1E-6 T 29-03-2018 CSW12_RS21000 fe463f8421604e8b613cf072955509e9 121 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 120 8.0E-62 T 29-03-2018 IPR020506 Uncharacterised protein family YqfZ CSW12_RS25820 ffdcf5b898a1bbcf84b9a4f609cd46e9 126 SUPERFAMILY SSF54593 1 125 3.66E-18 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS25820 ffdcf5b898a1bbcf84b9a4f609cd46e9 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 1.9E-6 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS25820 ffdcf5b898a1bbcf84b9a4f609cd46e9 126 Gene3D G3DSA:3.10.180.10 1 126 4.7E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS21625 27c348532a44db408f21cd489c3ffbc7 138 Gene3D G3DSA:1.10.10.10 1 138 5.8E-31 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21625 27c348532a44db408f21cd489c3ffbc7 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 125 1.1E-34 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS21625 27c348532a44db408f21cd489c3ffbc7 138 Pfam PF02082 Transcriptional regulator 1 82 2.2E-26 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS21625 27c348532a44db408f21cd489c3ffbc7 138 SUPERFAMILY SSF46785 2 125 9.43E-32 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21625 27c348532a44db408f21cd489c3ffbc7 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 29-03-2018 IPR030489 Transcription regulator Rrf2-type, conserved site CSW12_RS21620 18afb343b43df24ff5ded10f0cd433fa 381 Gene3D G3DSA:3.90.1150.10 264 381 7.9E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS21620 18afb343b43df24ff5ded10f0cd433fa 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 29-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CSW12_RS21620 18afb343b43df24ff5ded10f0cd433fa 381 Gene3D G3DSA:3.40.640.10 12 256 1.9E-57 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS21620 18afb343b43df24ff5ded10f0cd433fa 381 Pfam PF00266 Aminotransferase class-V 4 366 5.7E-84 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS21620 18afb343b43df24ff5ded10f0cd433fa 381 SUPERFAMILY SSF53383 3 374 8.47E-105 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS21620 18afb343b43df24ff5ded10f0cd433fa 381 PIRSF PIRSF005572 1 381 2.3E-124 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CSW12_RS25200 b3726c6db01e55b28e021d2ae70eb899 77 Pfam PF13127 Protein of unknown function (DUF3955) 11 69 1.6E-17 T 29-03-2018 IPR025016 Protein of unknown function DUF3955 CSW12_RS01080 c843def56736ace07b3fe9e4d1e99ebc 203 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 8 201 1.7E-45 T 29-03-2018 IPR014205 Sporulation protein YtaF CSW12_RS01080 c843def56736ace07b3fe9e4d1e99ebc 203 Pfam PF02659 Putative manganese efflux pump 41 200 6.7E-13 T 29-03-2018 IPR003810 Putative manganese efflux pump CSW12_RS12315 6621839d7f3f14d3ff28709e1c602b25 320 Pfam PF06166 Protein of unknown function (DUF979) 8 318 6.1E-124 T 29-03-2018 IPR009323 Protein of unknown function DUF979 CSW12_RS17300 dd219f205f317b0b83127daac83defe8 404 Gene3D G3DSA:3.40.50.410 213 399 4.3E-11 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS17300 dd219f205f317b0b83127daac83defe8 404 Pfam PF01882 Protein of unknown function DUF58 206 277 8.4E-20 T 29-03-2018 IPR002881 Domain of unknown function DUF58 CSW12_RS06335 7df744c6974e21b0137c4aaa1bad7b16 232 SUPERFAMILY SSF52540 4 215 5.53E-49 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS06335 7df744c6974e21b0137c4aaa1bad7b16 232 SMART SM00382 29 204 1.8E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS06335 7df744c6974e21b0137c4aaa1bad7b16 232 Gene3D G3DSA:3.40.50.300 1 231 4.7E-54 T 29-03-2018 CSW12_RS06335 7df744c6974e21b0137c4aaa1bad7b16 232 Pfam PF00005 ABC transporter 21 155 4.9E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 29-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 321 2.9E-65 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 6.4E-32 T 29-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.5E-36 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 9.5E-36 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 9.5E-36 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 9.5E-36 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 9.5E-36 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 Gene3D G3DSA:3.30.390.30 328 456 2.5E-36 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 Gene3D G3DSA:3.50.50.60 2 164 3.0E-26 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 9.4E-66 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 SUPERFAMILY SSF55424 336 458 2.75E-37 T 29-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 458 1.8E-166 T 29-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 Gene3D G3DSA:3.40.50.720 165 327 1.2E-31 T 29-03-2018 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 SUPERFAMILY SSF51905 4 366 1.38E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS13810 0e856045717e188bb0fcddb31f7b2336 459 PIRSF PIRSF000350 1 455 2.4E-85 T 29-03-2018 CSW12_RS02315 9d571607eae42c877b71597af128eb52 799 PIRSF PIRSF007519 1 799 0.0 T 29-03-2018 IPR012300 Peptidase M6, InhA CSW12_RS02315 9d571607eae42c877b71597af128eb52 799 Pfam PF05547 Immune inhibitor A peptidase M6 153 795 0.0 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS02315 9d571607eae42c877b71597af128eb52 799 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 188 497 1.6E-85 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS02315 9d571607eae42c877b71597af128eb52 799 SUPERFAMILY SSF55486 359 435 3.04E-17 T 29-03-2018 CSW12_RS02315 9d571607eae42c877b71597af128eb52 799 SUPERFAMILY SSF55486 266 309 3.04E-17 T 29-03-2018 CSW12_RS02315 9d571607eae42c877b71597af128eb52 799 Gene3D G3DSA:2.60.120.260 393 615 9.9E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS00125 5f548c07596b4f15962e592ff58d3e60 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 245 7.9E-43 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS30925 cccae7b5e21587f9f5d85369ffd98f34 142 SUPERFAMILY SSF52540 15 118 6.72E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30925 cccae7b5e21587f9f5d85369ffd98f34 142 Gene3D G3DSA:3.40.50.300 2 137 2.5E-7 T 29-03-2018 CSW12_RS16065 5445a785e5e7ed260fa7053be45653c8 245 Pfam PF02535 ZIP Zinc transporter 93 237 2.0E-15 T 29-03-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 SUPERFAMILY SSF51735 111 271 1.56E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 SMART SM00829 10 322 2.5E-59 T 29-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 SUPERFAMILY SSF50129 1 148 1.83E-37 T 29-03-2018 IPR011032 GroES-like CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 29-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.3E-10 T 29-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 Gene3D G3DSA:3.40.50.720 134 291 8.3E-33 T 29-03-2018 CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 Pfam PF00107 Zinc-binding dehydrogenase 150 278 6.9E-31 T 29-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CSW12_RS17340 63582c5309415b03db0901ca132c05bc 328 Gene3D G3DSA:3.90.180.10 1 133 2.7E-40 T 29-03-2018 CSW12_RS26205 15a99bcf3a6b8015529951a61c7c7738 339 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 70 326 3.1E-75 T 29-03-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 CSW12_RS26205 15a99bcf3a6b8015529951a61c7c7738 339 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 7 327 2.0E-126 T 29-03-2018 IPR014225 Sporulation stage II, protein D firmicutes CSW12_RS26205 15a99bcf3a6b8015529951a61c7c7738 339 Pfam PF08486 Stage II sporulation protein 65 167 2.3E-27 T 29-03-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal CSW12_RS00465 ba8e434a721e28cdb56e82fc12bf194e 163 Gene3D G3DSA:2.60.40.1240 39 163 2.0E-19 T 29-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CSW12_RS00465 ba8e434a721e28cdb56e82fc12bf194e 163 Pfam PF11611 Domain of unknown function (DUF4352) 40 148 1.7E-14 T 29-03-2018 IPR029051 Domain of unknown function DUF4352 CSW12_RS09255 428544c4e8a6ea29e7c2131f9fadc3e0 207 Pfam PF03458 UPF0126 domain 92 160 3.9E-17 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CSW12_RS09255 428544c4e8a6ea29e7c2131f9fadc3e0 207 Pfam PF03458 UPF0126 domain 5 78 1.4E-19 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CSW12_RS22130 e494fd27d13a539d99a85c375b5fd519 143 SUPERFAMILY SSF46785 3 137 4.85E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22130 e494fd27d13a539d99a85c375b5fd519 143 Pfam PF02082 Transcriptional regulator 1 81 6.7E-24 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS22130 e494fd27d13a539d99a85c375b5fd519 143 Gene3D G3DSA:1.10.10.10 1 143 7.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16470 a51e6cb4330aecfcea21d3be68019483 90 Pfam PF14122 YokU-like protein, putative antitoxin 2 88 4.1E-44 T 29-03-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU CSW12_RS16470 a51e6cb4330aecfcea21d3be68019483 90 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 49 4.4E-12 T 29-03-2018 IPR022453 Zinc finger, MqsA-type CSW12_RS16470 a51e6cb4330aecfcea21d3be68019483 90 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 2 90 3.8E-49 T 29-03-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU CSW12_RS07855 637672e6af750ac8d353337c0f22448b 70 Hamap MF_01553 UPF0356 protein . 1 69 22.889 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 CSW12_RS07855 637672e6af750ac8d353337c0f22448b 70 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 1.2E-27 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 CSW12_RS07855 637672e6af750ac8d353337c0f22448b 70 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 8.0E-33 T 29-03-2018 IPR009907 Protein of unknown function DUF1447 CSW12_RS16995 445aa8a2b746603ccf3695372be46442 145 Pfam PF07179 SseB protein N-terminal domain 9 130 7.7E-15 T 29-03-2018 IPR009839 SseB protein N-terminal domain CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 SMART SM00670 3 135 4.8E-18 T 29-03-2018 IPR002716 PIN domain CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 Gene3D G3DSA:3.40.50.300 232 439 5.7E-17 T 29-03-2018 CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 Gene3D G3DSA:3.40.50.1010 1 181 1.5E-36 T 29-03-2018 IPR029060 PIN domain-like CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 Pfam PF02562 PhoH-like protein 233 437 5.3E-53 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 SUPERFAMILY SSF52540 232 420 3.5E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 SUPERFAMILY SSF52540 26 122 3.5E-26 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07990 9ff3018b3a912ff431f8c3fde1d73b54 442 Pfam PF13638 PIN domain 5 147 3.6E-32 T 29-03-2018 IPR002716 PIN domain CSW12_RS04650 076e89a0d22d0ad2976200d6a684e064 472 Pfam PF03703 Bacterial PH domain 238 321 5.8E-12 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04650 076e89a0d22d0ad2976200d6a684e064 472 Pfam PF03703 Bacterial PH domain 391 464 8.4E-9 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04650 076e89a0d22d0ad2976200d6a684e064 472 Pfam PF03703 Bacterial PH domain 59 129 1.6E-15 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04650 076e89a0d22d0ad2976200d6a684e064 472 PIRSF PIRSF026631 1 472 3.6E-138 T 29-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CSW12_RS06215 6a986f22109171e9c12d36b7a3cb25f2 93 Pfam PF09388 Spo0E like sporulation regulatory protein 13 54 1.6E-14 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CSW12_RS06215 6a986f22109171e9c12d36b7a3cb25f2 93 SUPERFAMILY SSF140500 9 62 3.66E-15 T 29-03-2018 CSW12_RS10060 1fa4e8c278aabddd1df9fae37589711b 299 SUPERFAMILY SSF110296 6 120 7.72E-16 T 29-03-2018 CSW12_RS10060 1fa4e8c278aabddd1df9fae37589711b 299 Gene3D G3DSA:2.130.10.10 6 146 1.1E-13 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS10060 1fa4e8c278aabddd1df9fae37589711b 299 Gene3D G3DSA:2.130.10.10 147 294 0.0017 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS10060 1fa4e8c278aabddd1df9fae37589711b 299 SUPERFAMILY SSF82171 51 266 5.1E-5 T 29-03-2018 CSW12_RS21135 a754cf391dbee4724081db8ff6d68f68 319 SUPERFAMILY SSF52540 98 279 6.4E-40 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21135 a754cf391dbee4724081db8ff6d68f68 319 Pfam PF02562 PhoH-like protein 113 316 3.0E-95 T 29-03-2018 IPR003714 PhoH-like protein GO:0005524 CSW12_RS21135 a754cf391dbee4724081db8ff6d68f68 319 Gene3D G3DSA:3.40.50.300 110 316 1.8E-31 T 29-03-2018 CSW12_RS21140 cd8cd3a7b33401d3816e1b362c213b14 399 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 385 1.5E-120 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CSW12_RS21140 cd8cd3a7b33401d3816e1b362c213b14 399 PIRSF PIRSF029895 1 398 1.6E-171 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CSW12_RS21140 cd8cd3a7b33401d3816e1b362c213b14 399 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 387 3.8E-148 T 29-03-2018 IPR010690 Putative stage IV sporulation YqfD CSW12_RS25580 a4f3ac16ca38d9a135cd9fdbec8ba8c1 181 SUPERFAMILY SSF52218 3 169 1.21E-35 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS25580 a4f3ac16ca38d9a135cd9fdbec8ba8c1 181 Gene3D G3DSA:3.40.50.360 1 177 7.8E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS25580 a4f3ac16ca38d9a135cd9fdbec8ba8c1 181 Pfam PF03358 NADPH-dependent FMN reductase 3 120 1.5E-20 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 Gene3D G3DSA:3.40.50.2000 262 470 3.2E-39 T 29-03-2018 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 46.72 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 474 3.5E-179 T 29-03-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 Pfam PF08323 Starch synthase catalytic domain 2 237 2.1E-83 T 29-03-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 SUPERFAMILY SSF53756 3 476 4.54E-134 T 29-03-2018 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 Gene3D G3DSA:3.40.50.2000 10 261 2.9E-8 T 29-03-2018 CSW12_RS24080 e9d9c3831687a01f34f9a695c1f3f7bb 476 Pfam PF00534 Glycosyl transferases group 1 287 437 4.3E-19 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS30765 176f0a46e775b89f8db47403f7f3f0ed 316 Pfam PF13034 Protein of unknown function (DUF3895) 246 316 2.4E-14 T 29-03-2018 IPR024995 Protein of unknown function DUF3895 CSW12_RS20235 1e5806bea3fedf621c857d8fbd642188 292 Gene3D G3DSA:1.10.4100.10 77 269 3.1E-29 T 29-03-2018 CSW12_RS20235 1e5806bea3fedf621c857d8fbd642188 292 Pfam PF03313 Serine dehydratase alpha chain 14 274 9.5E-72 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CSW12_RS20235 1e5806bea3fedf621c857d8fbd642188 292 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 288 3.6E-132 T 29-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS08665 f511d7cfcd8064d924c5643222a4466c 263 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 221 247 - T 29-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CSW12_RS08665 f511d7cfcd8064d924c5643222a4466c 263 Pfam PF01148 Cytidylyltransferase family 2 262 7.2E-71 T 29-03-2018 CSW12_RS30700 5469726462f52fc815659e450782c48d 584 TIGRFAM TIGR00815 sulP: sulfate permease 9 533 2.5E-116 T 29-03-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 CSW12_RS30700 5469726462f52fc815659e450782c48d 584 Pfam PF00916 Sulfate permease family 15 379 1.3E-94 T 29-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CSW12_RS30700 5469726462f52fc815659e450782c48d 584 Gene3D G3DSA:3.30.750.24 420 549 1.4E-22 T 29-03-2018 IPR002645 STAS domain CSW12_RS30700 5469726462f52fc815659e450782c48d 584 Pfam PF01740 STAS domain 437 533 1.8E-18 T 29-03-2018 IPR002645 STAS domain CSW12_RS30700 5469726462f52fc815659e450782c48d 584 SUPERFAMILY SSF52091 436 539 2.94E-17 T 29-03-2018 IPR002645 STAS domain CSW12_RS06850 9bf53f89ad5dc147b0f33ba1ce059902 266 Pfam PF01925 Sulfite exporter TauE/SafE 7 259 9.3E-57 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS00090 e15b1e899b72d91b042440538dc04f28 54 Gene3D G3DSA:1.10.1220.10 4 44 1.3E-16 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CSW12_RS00090 e15b1e899b72d91b042440538dc04f28 54 Pfam PF05534 HicB family 4 38 3.9E-5 T 29-03-2018 IPR008651 Uncharacterised protein family HicB CSW12_RS00090 e15b1e899b72d91b042440538dc04f28 54 SUPERFAMILY SSF47598 2 47 2.06E-11 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CSW12_RS25115 e2b31ba99a82f284e9172f6dd791bb93 467 Pfam PF03050 Transposase IS66 family 159 428 8.1E-63 T 29-03-2018 IPR004291 Transposase, IS66 CSW12_RS25115 e2b31ba99a82f284e9172f6dd791bb93 467 Pfam PF13005 zinc-finger binding domain of transposase IS66 97 143 1.4E-9 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CSW12_RS29510 e2b31ba99a82f284e9172f6dd791bb93 467 Pfam PF03050 Transposase IS66 family 159 428 8.1E-63 T 29-03-2018 IPR004291 Transposase, IS66 CSW12_RS29510 e2b31ba99a82f284e9172f6dd791bb93 467 Pfam PF13005 zinc-finger binding domain of transposase IS66 97 143 1.4E-9 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CSW12_RS00760 e2b31ba99a82f284e9172f6dd791bb93 467 Pfam PF03050 Transposase IS66 family 159 428 8.1E-63 T 29-03-2018 IPR004291 Transposase, IS66 CSW12_RS00760 e2b31ba99a82f284e9172f6dd791bb93 467 Pfam PF13005 zinc-finger binding domain of transposase IS66 97 143 1.4E-9 T 29-03-2018 IPR024474 Zinc-finger binding domain of transposase IS66 CSW12_RS18280 5a5e893bdcf033f9fd31f8eeddd156fb 549 Pfam PF13115 YtkA-like 448 529 2.1E-12 T 29-03-2018 IPR032693 YtkA-like domain CSW12_RS18280 5a5e893bdcf033f9fd31f8eeddd156fb 549 Pfam PF04234 CopC domain 30 127 3.3E-19 T 29-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CSW12_RS18280 5a5e893bdcf033f9fd31f8eeddd156fb 549 Pfam PF05425 Copper resistance protein D 336 426 1.0E-16 T 29-03-2018 IPR008457 Copper resistance protein D GO:0016021 CSW12_RS18280 5a5e893bdcf033f9fd31f8eeddd156fb 549 Gene3D G3DSA:2.60.40.1220 29 128 2.1E-21 T 29-03-2018 CSW12_RS18280 5a5e893bdcf033f9fd31f8eeddd156fb 549 SUPERFAMILY SSF81296 29 127 1.82E-19 T 29-03-2018 IPR014756 Immunoglobulin E-set CSW12_RS11350 b3440a6e19152f0ba1ee5cdfa0af6d02 336 SUPERFAMILY SSF53474 187 314 1.62E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11350 b3440a6e19152f0ba1ee5cdfa0af6d02 336 SUPERFAMILY SSF53474 7 154 1.62E-36 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11350 b3440a6e19152f0ba1ee5cdfa0af6d02 336 Gene3D G3DSA:3.40.50.1820 3 285 9.0E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11350 b3440a6e19152f0ba1ee5cdfa0af6d02 336 Pfam PF12146 Serine aminopeptidase, S33 54 274 3.0E-18 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS23055 72b95c70ac4c6dd7f904fc1d5c294a64 59 SUPERFAMILY SSF48600 3 47 2.75E-5 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS23055 72b95c70ac4c6dd7f904fc1d5c294a64 59 Pfam PF01817 Chorismate mutase type II 4 45 1.7E-4 T 29-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS23055 72b95c70ac4c6dd7f904fc1d5c294a64 59 Gene3D G3DSA:1.20.59.10 1 48 9.6E-7 T 29-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 Gene3D G3DSA:3.90.1200.10 100 355 7.3E-14 T 29-03-2018 CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 SUPERFAMILY SSF56112 3 369 1.24E-85 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 Gene3D G3DSA:3.30.200.20 1 99 2.5E-34 T 29-03-2018 CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 393 183.955 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 Pfam PF01636 Phosphotransferase enzyme family 29 261 3.6E-11 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 PIRSF PIRSF031134 1 388 7.8E-157 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CSW12_RS07520 5f71a1caaeae2def0c16378d3e2cc98e 393 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 31 384 1.0E-135 T 29-03-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|KEGG: 00500+2.7.1.10|MetaCyc: PWY-6754 CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 Gene3D G3DSA:2.30.30.280 214 277 1.1E-23 T 29-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 Pfam PF03054 tRNA methyl transferase 9 357 1.9E-145 T 29-03-2018 CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 357 2.6E-138 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 Gene3D G3DSA:2.40.30.10 279 370 6.9E-29 T 29-03-2018 CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 358 40.474 T 29-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 Gene3D G3DSA:3.40.50.620 1 213 3.5E-70 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS21615 33465c0856648347d2cf1422f7199977 371 SUPERFAMILY SSF52402 7 244 6.4E-59 T 29-03-2018 CSW12_RS06640 2cf6cff01602403f6b34c90d85851f0d 107 SUPERFAMILY SSF101386 8 93 4.94E-25 T 29-03-2018 CSW12_RS06640 2cf6cff01602403f6b34c90d85851f0d 107 Gene3D G3DSA:1.10.287.1080 1 95 9.6E-25 T 29-03-2018 CSW12_RS06640 2cf6cff01602403f6b34c90d85851f0d 107 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 8 92 6.7E-20 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CSW12_RS06640 2cf6cff01602403f6b34c90d85851f0d 107 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 6 87 4.3E-33 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CSW12_RS06640 2cf6cff01602403f6b34c90d85851f0d 107 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 20.795 T 29-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CSW12_RS03650 b944552f9ee1ba5aa3741f3ca06827ed 381 Pfam PF04286 Protein of unknown function (DUF445) 17 379 4.9E-83 T 29-03-2018 IPR007383 Protein of unknown function DUF445 CSW12_RS03650 b944552f9ee1ba5aa3741f3ca06827ed 381 PIRSF PIRSF032178 4 381 9.5E-138 T 29-03-2018 IPR016991 Protein of unknown function UCP032178 CSW12_RS13185 00fc012a342b6426671283e671bed9b5 400 Gene3D G3DSA:3.40.640.10 48 299 8.0E-48 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS13185 00fc012a342b6426671283e671bed9b5 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CSW12_RS13185 00fc012a342b6426671283e671bed9b5 400 Gene3D G3DSA:3.90.1150.10 300 386 1.6E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS13185 00fc012a342b6426671283e671bed9b5 400 SUPERFAMILY SSF53383 6 385 3.71E-104 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS13185 00fc012a342b6426671283e671bed9b5 400 Pfam PF00155 Aminotransferase class I and II 34 383 1.7E-61 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS03300 b980a399a93b48a109569989147a4524 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 1.6E-19 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS03300 b980a399a93b48a109569989147a4524 101 Gene3D G3DSA:3.40.50.2300 1 101 5.1E-36 T 29-03-2018 CSW12_RS03300 b980a399a93b48a109569989147a4524 101 SUPERFAMILY SSF52794 1 98 6.41E-33 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS27560 e4108df975925ba716565dd6586ba65f 86 Pfam PF06257 Biofilm formation stimulator VEG 4 74 1.1E-29 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CSW12_RS27560 e4108df975925ba716565dd6586ba65f 86 Gene3D G3DSA:2.30.30.100 2 76 1.9E-31 T 29-03-2018 CSW12_RS27560 e4108df975925ba716565dd6586ba65f 86 PIRSF PIRSF037257 1 85 1.7E-35 T 29-03-2018 IPR009366 Protein Veg GO:0042710 CSW12_RS02050 4a9cad36ee14c42ebc0ef54afbedda4d 141 Pfam PF06114 IrrE N-terminal-like domain 27 139 1.1E-16 T 29-03-2018 IPR010359 IrrE N-terminal-like domain CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 151 4.9E-48 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 32.877 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 4.1E-39 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 4.1E-39 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 4.1E-39 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 4.1E-39 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 4.1E-39 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 PIRSF PIRSF006160 1 157 7.8E-59 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 Gene3D G3DSA:3.30.1360.80 1 147 1.2E-52 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 8.0E-81 T 29-03-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS23695 fe6d3d15bc78938f5e83751d3104569f 157 SUPERFAMILY SSF63411 4 152 1.74E-58 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS13325 b7a4f0facde21990d150ff72b51a9fcd 150 Pfam PF07552 Spore Coat Protein X and V domain 92 149 1.4E-21 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CSW12_RS13325 b7a4f0facde21990d150ff72b51a9fcd 150 Pfam PF07552 Spore Coat Protein X and V domain 29 85 2.0E-19 T 29-03-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 CSW12_RS08820 dd9088bf3bbedcd7199afd94e886bf62 358 Gene3D G3DSA:3.40.50.2300 156 348 2.0E-45 T 29-03-2018 CSW12_RS08820 dd9088bf3bbedcd7199afd94e886bf62 358 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 39 345 3.5E-88 T 29-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CSW12_RS08820 dd9088bf3bbedcd7199afd94e886bf62 358 Gene3D G3DSA:3.40.50.2300 36 155 3.1E-43 T 29-03-2018 CSW12_RS08820 dd9088bf3bbedcd7199afd94e886bf62 358 SUPERFAMILY SSF53822 51 278 9.16E-15 T 29-03-2018 IPR028082 Periplasmic binding protein-like I CSW12_RS07425 d3c1488ba3537b6729b68ae4728bdfd2 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 232 2.0E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS07425 d3c1488ba3537b6729b68ae4728bdfd2 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 257 3.9E-51 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07425 d3c1488ba3537b6729b68ae4728bdfd2 268 Gene3D G3DSA:3.40.50.1000 1 251 2.0E-30 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07425 d3c1488ba3537b6729b68ae4728bdfd2 268 SUPERFAMILY SSF56784 1 258 2.22E-55 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS07425 d3c1488ba3537b6729b68ae4728bdfd2 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 253 1.0E-49 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS23560 361e867444a09a10d03c71426081527f 306 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 54 293 6.5E-33 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CSW12_RS23560 361e867444a09a10d03c71426081527f 306 Gene3D G3DSA:3.40.1390.30 42 147 6.6E-12 T 29-03-2018 CSW12_RS23560 361e867444a09a10d03c71426081527f 306 Gene3D G3DSA:3.40.1390.30 148 275 6.6E-23 T 29-03-2018 CSW12_RS23560 361e867444a09a10d03c71426081527f 306 SUPERFAMILY SSF102705 53 303 7.72E-42 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CSW12_RS10640 33c93445b094d7ae166868876f1ec57f 472 PIRSF PIRSF006060 7 471 2.6E-67 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS10640 33c93445b094d7ae166868876f1ec57f 472 ProSitePatterns PS00218 Amino acid permeases signature. 48 78 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS10640 33c93445b094d7ae166868876f1ec57f 472 Pfam PF00324 Amino acid permease 23 433 1.4E-102 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 448 6.8E-148 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 Pfam PF01235 Sodium:alanine symporter family 50 460 4.4E-160 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 PRINTS PR00175 Sodium/alanine symporter signature 417 437 3.7E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 PRINTS PR00175 Sodium/alanine symporter signature 204 223 3.7E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 PRINTS PR00175 Sodium/alanine symporter signature 176 194 3.7E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 PRINTS PR00175 Sodium/alanine symporter signature 86 108 3.7E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 PRINTS PR00175 Sodium/alanine symporter signature 354 376 3.7E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS01890 835559bdce286e32cc6bfed6f3fae4ed 486 PRINTS PR00175 Sodium/alanine symporter signature 295 313 3.7E-57 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS03090 6bfc88bb305d5e3a2d8c52a12fc34b22 152 SUPERFAMILY SSF52833 50 148 8.22E-24 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS03090 6bfc88bb305d5e3a2d8c52a12fc34b22 152 Pfam PF00085 Thioredoxin 60 149 1.4E-16 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CSW12_RS03090 6bfc88bb305d5e3a2d8c52a12fc34b22 152 Gene3D G3DSA:3.40.30.10 21 152 5.1E-22 T 29-03-2018 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 Pfam PF13416 Bacterial extracellular solute-binding protein 56 357 3.9E-57 T 29-03-2018 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 Gene3D G3DSA:3.40.190.10 158 414 2.0E-44 T 29-03-2018 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 138 157 1.7E-7 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 245 264 1.7E-7 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 159 178 1.7E-7 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 78 96 1.7E-7 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 PRINTS PR00181 Maltose binding protein signature 370 389 1.7E-7 T 29-03-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0006810 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 Gene3D G3DSA:3.40.190.10 37 157 2.5E-8 T 29-03-2018 CSW12_RS07665 c8ae539bfa57bc9e56988739d7795b82 419 SUPERFAMILY SSF53850 42 407 3.78E-93 T 29-03-2018 CSW12_RS17095 330c50e5eeb4125a7dcf46609b17ec41 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 4.2E-64 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CSW12_RS17095 330c50e5eeb4125a7dcf46609b17ec41 144 Pfam PF06491 Disulphide isomerase 8 144 6.7E-61 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CSW12_RS24120 8156cb212164ffa55e57d694f9d9cefe 199 Gene3D G3DSA:1.10.357.10 2 197 2.2E-32 T 29-03-2018 CSW12_RS24120 8156cb212164ffa55e57d694f9d9cefe 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS24120 8156cb212164ffa55e57d694f9d9cefe 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.3E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS24120 8156cb212164ffa55e57d694f9d9cefe 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.5E-13 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS24120 8156cb212164ffa55e57d694f9d9cefe 199 SUPERFAMILY SSF46689 4 81 2.82E-17 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS20000 e717697bdb1d4fac9bb3a3c5421af501 178 Hamap MF_00760 UPF0302 protein . 2 178 33.36 T 29-03-2018 IPR011188 Uncharacterised protein family UPF0302 CSW12_RS20000 e717697bdb1d4fac9bb3a3c5421af501 178 Pfam PF08864 UPF0302 domain 9 113 5.7E-47 T 29-03-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal CSW12_RS20000 e717697bdb1d4fac9bb3a3c5421af501 178 SMART SM00914 139 175 1.7E-14 T 29-03-2018 IPR014957 IDEAL domain CSW12_RS20000 e717697bdb1d4fac9bb3a3c5421af501 178 PIRSF PIRSF007165 1 178 5.0E-83 T 29-03-2018 IPR011188 Uncharacterised protein family UPF0302 CSW12_RS20000 e717697bdb1d4fac9bb3a3c5421af501 178 Pfam PF08858 IDEAL domain 139 175 2.9E-16 T 29-03-2018 IPR014957 IDEAL domain CSW12_RS07285 14718a223145795447f5e80e972e44bc 139 Gene3D G3DSA:1.10.287.100 83 119 0.0011 T 29-03-2018 CSW12_RS07285 14718a223145795447f5e80e972e44bc 139 SMART SM00345 17 76 9.1E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS07285 14718a223145795447f5e80e972e44bc 139 Gene3D G3DSA:1.10.10.10 1 78 5.7E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07285 14718a223145795447f5e80e972e44bc 139 SUPERFAMILY SSF46785 6 78 1.31E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07285 14718a223145795447f5e80e972e44bc 139 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 4.6E-16 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS01195 50882a2f4ce95bf39a0c12bc38efe308 50 Pfam PF14139 YpzG-like protein 1 49 5.7E-26 T 29-03-2018 IPR025413 YpzG-like protein CSW12_RS01190 b72444a4a58f06b2746d933725ca96ec 105 Pfam PF08838 Protein of unknown function (DUF1811) 5 103 2.7E-40 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 CSW12_RS01190 b72444a4a58f06b2746d933725ca96ec 105 Gene3D G3DSA:1.10.287.880 3 52 3.9E-26 T 29-03-2018 CSW12_RS01190 b72444a4a58f06b2746d933725ca96ec 105 Gene3D G3DSA:2.30.30.340 53 104 3.5E-21 T 29-03-2018 CSW12_RS01190 b72444a4a58f06b2746d933725ca96ec 105 SUPERFAMILY SSF101697 3 105 3.01E-45 T 29-03-2018 IPR014938 Protein of unknown function DUF1811 CSW12_RS03050 1a09f518b023f1f6ef19440df1bd3cf9 153 Pfam PF01047 MarR family 42 98 1.4E-9 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS03050 1a09f518b023f1f6ef19440df1bd3cf9 153 SUPERFAMILY SSF46785 23 152 8.44E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03050 1a09f518b023f1f6ef19440df1bd3cf9 153 SMART SM00347 34 137 1.9E-12 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS03050 1a09f518b023f1f6ef19440df1bd3cf9 153 Gene3D G3DSA:1.10.10.10 2 141 1.9E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 SUPERFAMILY SSF90123 3 315 2.22E-77 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 Pfam PF00664 ABC transporter transmembrane region 17 285 6.0E-54 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 Gene3D G3DSA:1.20.1560.10 1 318 3.7E-66 T 29-03-2018 CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 Pfam PF00005 ABC transporter 348 497 4.1E-37 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 SUPERFAMILY SSF52540 321 568 4.35E-93 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 SMART SM00382 357 543 7.0E-17 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS25595 af8d92036539687339d9f7b9f3d870d3 570 Gene3D G3DSA:3.40.50.300 319 570 1.3E-78 T 29-03-2018 CSW12_RS04210 5fe6ca12ff257097158e14daed4804a3 45 TIGRFAM TIGR04429 Phr_nterm: Phr family secreted Rap phosphatase inhibitor 1 27 8.1E-8 T 29-03-2018 IPR030968 Phr family, secreted RapG/RapK phosphatase inhibitor CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 Gene3D G3DSA:1.20.1250.20 202 402 6.8E-34 T 29-03-2018 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 340 363 2.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 106 127 2.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 279 300 2.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 17 33 2.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 136 158 2.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 PRINTS PR01035 Tetracycline resistance protein signature 79 103 2.2E-7 T 29-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 Pfam PF07690 Major Facilitator Superfamily 12 228 1.8E-32 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 SUPERFAMILY SSF103473 5 392 1.66E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS18570 c11d3eaf0294fac422e93544c0205a5e 404 Gene3D G3DSA:1.20.1250.20 2 201 1.1E-35 T 29-03-2018 CSW12_RS03570 f36a257c50725222370f0ac5c55df1dc 69 SUPERFAMILY SSF53681 1 58 6.21E-6 T 29-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CSW12_RS03570 f36a257c50725222370f0ac5c55df1dc 69 Gene3D G3DSA:3.40.50.1860 1 66 2.3E-10 T 29-03-2018 CSW12_RS19350 a44486cf304de50f8c37b004fe356a6e 99 Pfam PF02049 Flagellar hook-basal body complex protein FliE 31 99 2.4E-13 T 29-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CSW12_RS23955 ec4f80f79992b4b4dcc22c180ce09f95 251 Gene3D G3DSA:3.20.20.70 5 247 7.8E-116 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS23955 ec4f80f79992b4b4dcc22c180ce09f95 251 TIGRFAM TIGR03581 EF_0839: conserved hypothetical protein EF_0839/AHA_3917 9 245 1.7E-118 T 29-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CSW12_RS23955 ec4f80f79992b4b4dcc22c180ce09f95 251 Pfam PF07071 KDGP aldolase 9 227 5.0E-106 T 29-03-2018 IPR010763 2-dehydro-3-deoxy-phosphogluconate aldolase KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 Gene3D G3DSA:3.30.190.20 145 224 5.2E-20 T 29-03-2018 CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 PIRSF PIRSF002155 1 227 1.8E-82 T 29-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 6.0E-107 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 8.6E-57 T 29-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 29-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.962 T 29-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 SUPERFAMILY SSF56808 6 226 1.28E-85 T 29-03-2018 IPR023674 Ribosomal protein L1-like CSW12_RS27920 549f817711fc77745411a28abcd3cfda 230 Gene3D G3DSA:3.40.50.790 68 144 6.7E-38 T 29-03-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CSW12_RS02340 0c62e44fb94339a3d65ef52e898b06fd 114 Pfam PF07885 Ion channel 30 99 6.1E-20 T 29-03-2018 IPR013099 Potassium channel domain CSW12_RS02340 0c62e44fb94339a3d65ef52e898b06fd 114 Gene3D G3DSA:1.10.287.70 18 112 2.1E-21 T 29-03-2018 CSW12_RS02340 0c62e44fb94339a3d65ef52e898b06fd 114 SUPERFAMILY SSF81324 7 106 4.06E-22 T 29-03-2018 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 SUPERFAMILY SSF55021 77 157 5.04E-24 T 29-03-2018 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 Gene3D G3DSA:3.30.70.260 2 88 1.6E-23 T 29-03-2018 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 Gene3D G3DSA:3.30.70.1150 89 160 1.1E-27 T 29-03-2018 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 157 2.9E-59 T 29-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 1.0E-28 T 29-03-2018 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 Pfam PF13710 ACT domain 12 74 8.4E-14 T 29-03-2018 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 Pfam PF10369 Small subunit of acetolactate synthase 85 156 4.3E-26 T 29-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CSW12_RS06570 4729862d13ef11870e05f8bd7e61bae0 169 SUPERFAMILY SSF55021 2 77 6.2E-19 T 29-03-2018 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Gene3D G3DSA:1.25.40.10 202 418 2.2E-16 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Gene3D G3DSA:1.25.40.10 61 134 7.0E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Gene3D G3DSA:1.25.40.10 135 201 1.5E-9 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 SUPERFAMILY SSF48452 15 228 2.02E-20 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 SUPERFAMILY SSF48452 215 320 1.18E-7 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 SMART SM00028 88 121 88.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 SMART SM00028 21 54 34.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 SMART SM00028 287 320 270.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 SMART SM00028 184 217 0.0048 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Gene3D G3DSA:1.25.40.10 39 60 0.0089 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Gene3D G3DSA:1.10.10.60 419 501 0.0042 T 29-03-2018 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Pfam PF13432 Tetratricopeptide repeat 156 217 3.8E-7 T 29-03-2018 CSW12_RS25490 e34c77e732a0712c4b4a5dddca0746ea 503 Gene3D G3DSA:1.20.58.280 3 38 0.02 T 29-03-2018 CSW12_RS02060 c994c9fb7be13f0e9dd329b155f6f5ef 61 SUPERFAMILY SSF47413 3 42 1.16E-7 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02060 c994c9fb7be13f0e9dd329b155f6f5ef 61 Gene3D G3DSA:1.10.260.40 1 61 4.7E-9 T 29-03-2018 CSW12_RS18925 7adbdaf95f5d97dedd5382e0ce23f497 270 Pfam PF05569 BlaR1 peptidase M56 51 232 3.3E-13 T 29-03-2018 IPR008756 Peptidase M56 CSW12_RS18925 7adbdaf95f5d97dedd5382e0ce23f497 270 Gene3D G3DSA:3.30.2010.10 78 159 2.5E-8 T 29-03-2018 CSW12_RS03410 8c70427637a23cf402dcb08b50b6a3ef 114 Pfam PF13157 Protein of unknown function (DUF3992) 21 109 1.9E-34 T 29-03-2018 IPR025055 Protein of unknown function DUF3992 CSW12_RS20640 e1ab3bb6a5116180a03eb4f56b22b498 127 Pfam PF00581 Rhodanese-like domain 43 121 7.8E-19 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS20640 e1ab3bb6a5116180a03eb4f56b22b498 127 SMART SM00450 31 126 2.6E-26 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS20640 e1ab3bb6a5116180a03eb4f56b22b498 127 Gene3D G3DSA:3.40.250.10 22 126 1.0E-27 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS20640 e1ab3bb6a5116180a03eb4f56b22b498 127 SUPERFAMILY SSF52821 11 121 1.83E-33 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS25800 aa9bbf9a467d7185851a933ff2ebb761 433 PIRSF PIRSF006351 1 433 5.8E-151 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS25800 aa9bbf9a467d7185851a933ff2ebb761 433 Pfam PF02378 Phosphotransferase system, EIIC 26 356 4.8E-71 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS25800 aa9bbf9a467d7185851a933ff2ebb761 433 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 431 1.5E-176 T 29-03-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 CSW12_RS25800 aa9bbf9a467d7185851a933ff2ebb761 433 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 9 431 1.5E-176 T 29-03-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 CSW12_RS10785 06a74041b1b2a0de7ea94c32cc466d8c 253 Gene3D G3DSA:3.90.550.10 2 243 2.8E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10785 06a74041b1b2a0de7ea94c32cc466d8c 253 Pfam PF00535 Glycosyl transferase family 2 19 116 4.0E-21 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS10785 06a74041b1b2a0de7ea94c32cc466d8c 253 SUPERFAMILY SSF53448 16 226 3.99E-35 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS10785 06a74041b1b2a0de7ea94c32cc466d8c 253 Pfam PF02709 N-terminal domain of galactosyltransferase 154 195 2.1E-5 T 29-03-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 2.6E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 2.6E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 2.6E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 256 263 2.6E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 2.6E-11 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 Gene3D G3DSA:3.30.2140.10 176 263 1.6E-7 T 29-03-2018 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 Gene3D G3DSA:3.30.2140.10 3 175 4.1E-26 T 29-03-2018 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 SUPERFAMILY SSF54001 2 263 8.83E-67 T 29-03-2018 CSW12_RS10485 1143ed2162ba63572f5cab2b57db5b05 263 Pfam PF00797 N-acetyltransferase 23 263 2.2E-45 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS19430 f026b4a2f8d6849e711eb5a0133ed0e2 122 Pfam PF00072 Response regulator receiver domain 5 116 8.8E-30 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS19430 f026b4a2f8d6849e711eb5a0133ed0e2 122 SUPERFAMILY SSF52172 4 120 7.68E-36 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS19430 f026b4a2f8d6849e711eb5a0133ed0e2 122 Gene3D G3DSA:3.40.50.2300 2 122 1.4E-35 T 29-03-2018 CSW12_RS19430 f026b4a2f8d6849e711eb5a0133ed0e2 122 SMART SM00448 3 116 5.9E-33 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS17445 d5e18922483d78b1dece31655fd909c2 188 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 4.4E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17445 d5e18922483d78b1dece31655fd909c2 188 SUPERFAMILY SSF55729 3 177 1.5E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17445 d5e18922483d78b1dece31655fd909c2 188 Gene3D G3DSA:3.40.630.30 1 184 7.8E-30 T 29-03-2018 CSW12_RS07670 3d73d0d1a8db144e6c6da6def1212399 433 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 215 419 1.1E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS07670 3d73d0d1a8db144e6c6da6def1212399 433 SUPERFAMILY SSF160964 86 100 5.49E-10 T 29-03-2018 CSW12_RS07670 3d73d0d1a8db144e6c6da6def1212399 433 SUPERFAMILY SSF160964 128 185 5.49E-10 T 29-03-2018 CSW12_RS07670 3d73d0d1a8db144e6c6da6def1212399 433 Gene3D G3DSA:1.20.58.370 30 165 1.6E-11 T 29-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CSW12_RS07670 3d73d0d1a8db144e6c6da6def1212399 433 Gene3D G3DSA:1.10.3720.10 190 426 1.9E-44 T 29-03-2018 CSW12_RS07670 3d73d0d1a8db144e6c6da6def1212399 433 SUPERFAMILY SSF161098 180 417 7.46E-57 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28975 b715bede0d85aded09047a077f682a0b 258 Gene3D G3DSA:3.40.50.150 6 227 4.4E-19 T 29-03-2018 CSW12_RS28975 b715bede0d85aded09047a077f682a0b 258 Pfam PF08242 Methyltransferase domain 80 174 1.6E-12 T 29-03-2018 IPR013217 Methyltransferase type 12 CSW12_RS28975 b715bede0d85aded09047a077f682a0b 258 SUPERFAMILY SSF53335 49 221 2.66E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS29050 b715bede0d85aded09047a077f682a0b 258 Gene3D G3DSA:3.40.50.150 6 227 4.4E-19 T 29-03-2018 CSW12_RS29050 b715bede0d85aded09047a077f682a0b 258 Pfam PF08242 Methyltransferase domain 80 174 1.6E-12 T 29-03-2018 IPR013217 Methyltransferase type 12 CSW12_RS29050 b715bede0d85aded09047a077f682a0b 258 SUPERFAMILY SSF53335 49 221 2.66E-21 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS23440 bc81764b06ab5bf9ea37b62f1129391d 319 Pfam PF04055 Radical SAM superfamily 52 214 1.5E-14 T 29-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CSW12_RS23440 bc81764b06ab5bf9ea37b62f1129391d 319 Pfam PF16199 Radical_SAM C-terminal domain 220 302 4.7E-25 T 29-03-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CSW12_RS23440 bc81764b06ab5bf9ea37b62f1129391d 319 SUPERFAMILY SSF102114 5 308 1.26E-52 T 29-03-2018 CSW12_RS23440 bc81764b06ab5bf9ea37b62f1129391d 319 SMART SM00729 32 259 2.8E-42 T 29-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CSW12_RS23440 bc81764b06ab5bf9ea37b62f1129391d 319 Gene3D G3DSA:3.20.20.70 9 272 2.0E-33 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS23440 bc81764b06ab5bf9ea37b62f1129391d 319 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 312 1.1E-127 T 29-03-2018 IPR005911 Protein YhcC-like GO:0051536 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 SUPERFAMILY SSF47384 182 248 1.57E-9 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 Gene3D G3DSA:3.30.565.10 255 404 6.0E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 193 248 1.3E-6 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 SUPERFAMILY SSF55874 254 400 2.23E-28 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 296 400 3.1E-13 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 SMART SM00387 295 402 8.0E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 SMART SM00388 191 253 0.0019 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 Gene3D G3DSA:1.10.287.130 177 248 6.2E-9 T 29-03-2018 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 380 3.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 399 3.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 361 3.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS23605 7856fd2b52c9dc9c299b07388b02e37d 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 347 3.7E-10 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS01495 393dbcf8662dfdeaa28a13bb4181197d 522 Pfam PF15975 Flotillin 378 471 1.5E-14 T 29-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CSW12_RS01495 393dbcf8662dfdeaa28a13bb4181197d 522 SUPERFAMILY SSF117892 68 210 1.24E-33 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS01495 393dbcf8662dfdeaa28a13bb4181197d 522 SMART SM00244 34 203 0.0021 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS01495 393dbcf8662dfdeaa28a13bb4181197d 522 Pfam PF01145 SPFH domain / Band 7 family 28 220 4.8E-23 T 29-03-2018 IPR001107 Band 7 domain CSW12_RS14300 1e5a1435c31b58cafee7556d21009f6c 115 SUPERFAMILY SSF102705 6 108 1.61E-17 T 29-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CSW12_RS14300 1e5a1435c31b58cafee7556d21009f6c 115 Gene3D G3DSA:3.30.70.120 2 107 7.2E-28 T 29-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CSW12_RS14300 1e5a1435c31b58cafee7556d21009f6c 115 Pfam PF03091 CutA1 divalent ion tolerance protein 62 105 9.6E-8 T 29-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CSW12_RS14860 8c9e9af6769f981a06c25f0b8efebc10 264 Gene3D G3DSA:3.10.180.10 1 125 1.9E-8 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS14860 8c9e9af6769f981a06c25f0b8efebc10 264 Gene3D G3DSA:3.10.180.10 140 247 0.57 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS14860 8c9e9af6769f981a06c25f0b8efebc10 264 SUPERFAMILY SSF54593 2 118 3.13E-10 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS12510 af9eb729d12349a041656df5e3afa761 263 SMART SM00773 1 72 4.1E-20 T 29-03-2018 IPR008893 WGR domain CSW12_RS12510 af9eb729d12349a041656df5e3afa761 263 Pfam PF14024 Protein of unknown function (DUF4240) 81 205 1.2E-39 T 29-03-2018 IPR025334 Domain of unknown function (DUF4240 CSW12_RS12510 af9eb729d12349a041656df5e3afa761 263 SUPERFAMILY SSF142921 10 67 3.27E-9 T 29-03-2018 IPR008893 WGR domain CSW12_RS12510 af9eb729d12349a041656df5e3afa761 263 Pfam PF05406 WGR domain 7 67 1.7E-16 T 29-03-2018 IPR008893 WGR domain CSW12_RS12510 af9eb729d12349a041656df5e3afa761 263 Gene3D G3DSA:2.20.140.10 2 68 1.6E-12 T 29-03-2018 IPR008893 WGR domain CSW12_RS12305 94acbc2ec93d82065c928a8a8afd93e7 253 Pfam PF03746 LamB/YcsF family 4 241 1.4E-104 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CSW12_RS12305 94acbc2ec93d82065c928a8a8afd93e7 253 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 247 47.477 T 29-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CSW12_RS12305 94acbc2ec93d82065c928a8a8afd93e7 253 SUPERFAMILY SSF88713 3 250 6.74E-101 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS12305 94acbc2ec93d82065c928a8a8afd93e7 253 Gene3D G3DSA:3.20.20.370 3 251 1.1E-107 T 29-03-2018 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 8.9E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 SUPERFAMILY SSF50249 1 64 1.14E-25 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 PIRSF PIRSF002599 1 66 2.1E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 29-03-2018 IPR019844 Cold-shock conserved site CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 PRINTS PR00050 Cold shock protein signature 24 33 1.8E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 PRINTS PR00050 Cold shock protein signature 39 57 1.8E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 SMART SM00357 3 66 7.2E-31 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS10065 ecf94cf431c6c2a45007e600117fa77d 66 Gene3D G3DSA:2.40.50.140 1 66 3.0E-29 T 29-03-2018 CSW12_RS24430 f59c594ad1da2ee453ef4489c9c63573 159 Pfam PF14526 Integron-associated effector binding protein 7 157 7.2E-30 T 29-03-2018 IPR029441 Integron-associated effector binding protein CSW12_RS24430 f59c594ad1da2ee453ef4489c9c63573 159 Gene3D G3DSA:3.20.80.10 1 158 8.2E-42 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS24430 f59c594ad1da2ee453ef4489c9c63573 159 SUPERFAMILY SSF55136 6 158 3.66E-24 T 29-03-2018 CSW12_RS24430 f59c594ad1da2ee453ef4489c9c63573 159 SMART SM00871 3 159 6.0E-36 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS03900 2fff993bac2c5fe2161895e50cd2394e 225 PIRSF PIRSF006171 1 224 2.1E-78 T 29-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CSW12_RS03900 2fff993bac2c5fe2161895e50cd2394e 225 Pfam PF00072 Response regulator receiver domain 4 115 1.0E-19 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS03900 2fff993bac2c5fe2161895e50cd2394e 225 Gene3D G3DSA:1.10.10.10 159 224 1.3E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03900 2fff993bac2c5fe2161895e50cd2394e 225 SUPERFAMILY SSF52172 1 140 2.99E-27 T 29-03-2018 IPR011006 CheY-like superfamily CSW12_RS03900 2fff993bac2c5fe2161895e50cd2394e 225 SMART SM00448 2 115 5.1E-17 T 29-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CSW12_RS03900 2fff993bac2c5fe2161895e50cd2394e 225 Gene3D G3DSA:3.40.50.2300 1 143 1.7E-26 T 29-03-2018 CSW12_RS05250 abed0bcb485e77e91bcb44f9d5c29fe9 279 Gene3D G3DSA:2.30.30.410 201 277 4.6E-4 T 29-03-2018 CSW12_RS05250 abed0bcb485e77e91bcb44f9d5c29fe9 279 SUPERFAMILY SSF51445 5 199 2.91E-35 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS05250 abed0bcb485e77e91bcb44f9d5c29fe9 279 Gene3D G3DSA:3.20.20.80 1 200 1.5E-41 T 29-03-2018 CSW12_RS05250 abed0bcb485e77e91bcb44f9d5c29fe9 279 Pfam PF01183 Glycosyl hydrolases family 25 6 180 1.3E-21 T 29-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CSW12_RS21810 0485489e37d77d89d6e9481e0d1df4cb 637 Pfam PF02687 FtsX-like permease family 84 178 4.8E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS21810 0485489e37d77d89d6e9481e0d1df4cb 637 PIRSF PIRSF018968 1 636 7.4E-100 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS08085 92e028b0ffc4494abc4780e380dc878b 150 Gene3D G3DSA:1.20.1500.10 10 119 9.6E-30 T 29-03-2018 IPR023378 YheA/YmcA-like domain CSW12_RS08085 92e028b0ffc4494abc4780e380dc878b 150 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 116 8.1E-23 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CSW12_RS08085 92e028b0ffc4494abc4780e380dc878b 150 SUPERFAMILY SSF158622 6 127 3.27E-34 T 29-03-2018 IPR023378 YheA/YmcA-like domain CSW12_RS01585 07c5f08494b5656c180089ffbd43a296 251 Pfam PF13529 Peptidase_C39 like family 59 218 7.8E-45 T 29-03-2018 CSW12_RS01585 07c5f08494b5656c180089ffbd43a296 251 Gene3D G3DSA:3.90.70.10 68 251 6.8E-25 T 29-03-2018 CSW12_RS01585 07c5f08494b5656c180089ffbd43a296 251 PIRSF PIRSF032442 2 248 2.2E-85 T 29-03-2018 IPR016997 Uncharacterised conserved protein UCP032442 CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 SUPERFAMILY SSF52540 1023 1315 1.1E-48 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 Pfam PF09397 Ftsk gamma domain 1339 1399 7.1E-28 T 29-03-2018 IPR018541 FtsK gamma domain CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 Pfam PF01580 FtsK/SpoIIIE family 1189 1242 1.0E-15 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 Pfam PF01580 FtsK/SpoIIIE family 1050 1185 2.5E-47 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 Gene3D G3DSA:3.40.50.300 662 1412 4.8E-55 T 29-03-2018 CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 SMART SM00382 1085 1263 0.0068 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 SMART SM00843 1337 1402 6.1E-38 T 29-03-2018 IPR018541 FtsK gamma domain CSW12_RS23125 f6f07121d437d658e8bef74d43b9038b 1412 SUPERFAMILY SSF46785 1338 1403 3.06E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12505 1a93adc78f70900f5b09056be69791da 345 Gene3D G3DSA:3.40.50.720 1 323 4.4E-28 T 29-03-2018 CSW12_RS12505 1a93adc78f70900f5b09056be69791da 345 SUPERFAMILY SSF51735 1 318 5.04E-35 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS12505 1a93adc78f70900f5b09056be69791da 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 82 221 2.5E-5 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS21885 b7089feae95ccb7acc5e656b604b310d 181 Pfam PF04093 rod shape-determining protein MreD 7 166 2.0E-24 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CSW12_RS21885 b7089feae95ccb7acc5e656b604b310d 181 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 11 163 1.0E-28 T 29-03-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CSW12_RS24875 0bb0be1e8ea2943ca4c39f82ef342170 412 Gene3D G3DSA:1.20.1250.20 14 216 1.1E-24 T 29-03-2018 CSW12_RS24875 0bb0be1e8ea2943ca4c39f82ef342170 412 Gene3D G3DSA:1.20.1250.20 217 410 2.8E-26 T 29-03-2018 CSW12_RS24875 0bb0be1e8ea2943ca4c39f82ef342170 412 SUPERFAMILY SSF103473 25 399 1.57E-63 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS24875 0bb0be1e8ea2943ca4c39f82ef342170 412 Pfam PF07690 Major Facilitator Superfamily 30 362 4.2E-45 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS12515 ad96f7679651ce061e451249663db963 155 Gene3D G3DSA:3.90.79.10 2 155 2.4E-20 T 29-03-2018 CSW12_RS12515 ad96f7679651ce061e451249663db963 155 SUPERFAMILY SSF55811 13 149 8.39E-24 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS12515 ad96f7679651ce061e451249663db963 155 Pfam PF00293 NUDIX domain 19 129 6.7E-15 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS12515 ad96f7679651ce061e451249663db963 155 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS04300 95c2c4a1fbe4524ba978a3b4ad271127 146 Gene3D G3DSA:1.20.1260.10 1 139 8.3E-25 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS04300 95c2c4a1fbe4524ba978a3b4ad271127 146 SUPERFAMILY SSF47240 6 140 4.26E-29 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS04300 95c2c4a1fbe4524ba978a3b4ad271127 146 Pfam PF00210 Ferritin-like domain 9 140 1.8E-25 T 29-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CSW12_RS27160 c1f9cc4ab62480baa420b7160d965dd4 280 Pfam PF09648 YycH protein 33 252 1.5E-59 T 29-03-2018 IPR018604 Regulatory protein YycH-like GO:0016021 CSW12_RS16880 039688078c69422105c133be408ef7b1 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 179 4.3E-35 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16880 039688078c69422105c133be408ef7b1 215 SUPERFAMILY SSF56784 1 209 1.15E-44 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16880 039688078c69422105c133be408ef7b1 215 Gene3D G3DSA:3.40.50.1000 2 205 1.4E-30 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS16880 039688078c69422105c133be408ef7b1 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 173 4.5E-6 T 29-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CSW12_RS03370 17d984674515ff8b450f4d122cbabc10 91 PIRSF PIRSF010606 3 91 1.9E-43 T 29-03-2018 IPR016571 Spore coat assembly protein CotJB CSW12_RS03370 17d984674515ff8b450f4d122cbabc10 91 Pfam PF12652 CotJB protein 15 90 6.5E-29 T 29-03-2018 IPR024207 Spore coat assembly protein CotJB, domain CSW12_RS06430 b1b564622ca6cddf9b3f3ed1ca65eb41 148 TIGRFAM TIGR01753 flav_short: flavodoxin 6 144 8.4E-45 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CSW12_RS06430 b1b564622ca6cddf9b3f3ed1ca65eb41 148 Pfam PF00258 Flavodoxin 7 138 2.8E-26 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CSW12_RS06430 b1b564622ca6cddf9b3f3ed1ca65eb41 148 SUPERFAMILY SSF52218 3 147 3.63E-39 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS06430 b1b564622ca6cddf9b3f3ed1ca65eb41 148 Gene3D G3DSA:3.40.50.360 2 148 7.1E-32 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS13465 25a9408677f16336a6bb45bfa8b7aab3 254 Pfam PF08876 Domain of unknown function (DUF1836) 70 166 3.4E-16 T 29-03-2018 IPR014975 Protein of unknown function DUF1836 CSW12_RS00510 97ca4a7cea1f966d212675a7092cc372 172 Pfam PF07308 Protein of unknown function (DUF1456) 5 86 3.3E-27 T 29-03-2018 IPR009921 Domain of unknown function DUF1456 CSW12_RS00510 97ca4a7cea1f966d212675a7092cc372 172 Pfam PF07308 Protein of unknown function (DUF1456) 105 172 2.0E-21 T 29-03-2018 IPR009921 Domain of unknown function DUF1456 CSW12_RS00510 97ca4a7cea1f966d212675a7092cc372 172 Gene3D G3DSA:3.30.56.10 13 75 0.29 T 29-03-2018 CSW12_RS12605 5f18ae996f51bc5bfb5785ae00c8e59b 370 Pfam PF13210 Domain of unknown function (DUF4018) 49 240 2.5E-102 T 29-03-2018 IPR025089 Protein of unknown function DUF4018 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 Hamap MF_01974 Methionine aminopeptidase [map]. 17 264 35.774 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 Pfam PF00557 Metallopeptidase family M24 27 254 3.0E-47 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 SUPERFAMILY SSF55920 14 262 3.27E-70 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 173 185 6.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 205 217 6.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 82 95 6.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 120 6.5E-21 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 17 263 8.6E-90 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS26575 ba77aac4833d5956a84edf70aaaec052 264 Gene3D G3DSA:3.90.230.10 17 264 5.3E-66 T 29-03-2018 CSW12_RS06885 87eba1be070b57c3ec8dbdd9a9afc6b2 281 Gene3D G3DSA:3.20.20.410 1 280 5.2E-79 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CSW12_RS06885 87eba1be070b57c3ec8dbdd9a9afc6b2 281 Pfam PF01904 Protein of unknown function DUF72 17 264 1.2E-58 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CSW12_RS06885 87eba1be070b57c3ec8dbdd9a9afc6b2 281 SUPERFAMILY SSF117396 2 267 4.58E-84 T 29-03-2018 IPR002763 Protein of unknown function DUF72 CSW12_RS29495 b26d4c2f294e4343c17f9dd7f6846d54 291 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 11 287 1.8E-65 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS29495 b26d4c2f294e4343c17f9dd7f6846d54 291 Gene3D G3DSA:1.10.10.60 227 291 1.3E-4 T 29-03-2018 CSW12_RS29495 b26d4c2f294e4343c17f9dd7f6846d54 291 Pfam PF12784 PD-(D/E)XK nuclease family transposase 10 246 3.4E-64 T 29-03-2018 CSW12_RS16035 aa948efde23051bb6c5b1435fb2f1cae 141 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 3.4E-28 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CSW12_RS00835 06e174ae27584398b2b21f09e7999871 104 SUPERFAMILY SSF52833 3 100 1.86E-14 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS00835 06e174ae27584398b2b21f09e7999871 104 Gene3D G3DSA:3.40.30.10 1 104 1.2E-10 T 29-03-2018 CSW12_RS23075 b1ad6db0965cfa9d54f38cdbffa65f09 170 Gene3D G3DSA:1.20.1480.30 23 121 1.8E-8 T 29-03-2018 CSW12_RS23075 b1ad6db0965cfa9d54f38cdbffa65f09 170 Pfam PF06103 Bacterial protein of unknown function (DUF948) 7 94 1.6E-27 T 29-03-2018 IPR009293 Uncharacterised protein family UPF0478 CSW12_RS15705 aa763ece9516f214dd0070a6255929e8 109 PIRSF PIRSF031804 1 108 1.4E-35 T 29-03-2018 IPR016983 Uncharacterised conserved protein UCP031804 CSW12_RS15705 aa763ece9516f214dd0070a6255929e8 109 Pfam PF06803 Protein of unknown function (DUF1232) 41 78 2.8E-6 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CSW12_RS03485 f950c4cc7ff6cd7a418221db1933f706 303 SUPERFAMILY SSF103481 38 140 2.35E-18 T 29-03-2018 CSW12_RS03485 f950c4cc7ff6cd7a418221db1933f706 303 SUPERFAMILY SSF103481 189 286 5.75E-16 T 29-03-2018 CSW12_RS03485 f950c4cc7ff6cd7a418221db1933f706 303 Pfam PF00892 EamA-like transporter family 5 137 3.3E-29 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS03485 f950c4cc7ff6cd7a418221db1933f706 303 Pfam PF00892 EamA-like transporter family 152 284 1.5E-29 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 PIRSF PIRSF002808 7 449 1.0E-164 T 29-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 ProSitePatterns PS00942 glpT family of transporters signature. 155 171 - T 29-03-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site GO:0005215|GO:0006810|GO:0016021 Reactome: R-HSA-70153 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 5 442 2.1E-227 T 29-03-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 Gene3D G3DSA:1.20.1250.20 20 228 2.0E-33 T 29-03-2018 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 Pfam PF07690 Major Facilitator Superfamily 36 403 8.9E-51 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 37 421 3.1E-155 T 29-03-2018 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 Gene3D G3DSA:1.20.1250.20 244 449 2.9E-28 T 29-03-2018 CSW12_RS02010 7892a190a111b6772c4bab969aac2940 449 SUPERFAMILY SSF103473 13 439 7.06E-80 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 89 111 - T 29-03-2018 IPR023765 Solute-binding protein family 5, conserved site CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 SUPERFAMILY SSF53850 38 518 1.71E-123 T 29-03-2018 CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 Gene3D G3DSA:3.90.76.10 51 196 2.0E-31 T 29-03-2018 CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 Gene3D G3DSA:3.40.190.10 197 290 2.3E-25 T 29-03-2018 CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 PIRSF PIRSF002741 1 524 2.6E-118 T 29-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 Gene3D G3DSA:3.10.105.10 291 497 9.0E-50 T 29-03-2018 CSW12_RS03830 99c6929a9f1095fff12781c6802e7a67 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 87 445 4.8E-83 T 29-03-2018 IPR000914 Solute-binding protein family 5 domain CSW12_RS02460 4f4554ad21364ef5785e7787e91843d7 539 Pfam PF03354 Phage Terminase 54 510 6.7E-43 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CSW12_RS24570 71e1e1f91cdfddadc5d819a1230124bc 159 SUPERFAMILY SSF55729 3 138 7.78E-16 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS24570 71e1e1f91cdfddadc5d819a1230124bc 159 Gene3D G3DSA:3.40.630.30 1 139 9.4E-14 T 29-03-2018 CSW12_RS24570 71e1e1f91cdfddadc5d819a1230124bc 159 Pfam PF13302 Acetyltransferase (GNAT) domain 40 137 4.8E-7 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS10950 e79d5ab22f733db7a407f4cad0f61010 439 Pfam PF03222 Tryptophan/tyrosine permease family 40 417 1.3E-17 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 SUPERFAMILY SSF53383 1 390 8.38E-120 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 Gene3D G3DSA:3.40.640.10 45 296 6.5E-62 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 Gene3D G3DSA:3.90.1150.10 297 390 9.4E-21 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 Pfam PF00155 Aminotransferase class I and II 31 385 2.3E-82 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 29-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 2.2E-17 T 29-03-2018 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 2.2E-17 T 29-03-2018 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 2.2E-17 T 29-03-2018 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 2.2E-17 T 29-03-2018 CSW12_RS19865 01d307ee276cac0dc0765cdfc72800ca 395 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 2.2E-17 T 29-03-2018 CSW12_RS19600 aa81d81a7d73836646aa209b322cfd68 303 SUPERFAMILY SSF103481 42 145 3.66E-12 T 29-03-2018 CSW12_RS19600 aa81d81a7d73836646aa209b322cfd68 303 SUPERFAMILY SSF103481 197 296 3.4E-16 T 29-03-2018 CSW12_RS19600 aa81d81a7d73836646aa209b322cfd68 303 Pfam PF00892 EamA-like transporter family 10 142 1.0E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS19600 aa81d81a7d73836646aa209b322cfd68 303 Pfam PF00892 EamA-like transporter family 151 290 2.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS04110 318b2998095180c84434e0ee69c8f9fa 391 SUPERFAMILY SSF103473 4 377 2.75E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS04110 318b2998095180c84434e0ee69c8f9fa 391 Gene3D G3DSA:1.20.1250.20 193 379 2.9E-14 T 29-03-2018 CSW12_RS04110 318b2998095180c84434e0ee69c8f9fa 391 Pfam PF07690 Major Facilitator Superfamily 12 283 5.0E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS04110 318b2998095180c84434e0ee69c8f9fa 391 Gene3D G3DSA:1.20.1250.20 1 192 1.4E-26 T 29-03-2018 CSW12_RS03785 f1c6c4606d73eccfdd818ca2866717ff 108 Gene3D G3DSA:1.10.287.1080 21 97 6.8E-4 T 29-03-2018 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 157 6.3E-75 T 29-03-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 SUPERFAMILY SSF55811 27 109 5.15E-22 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 Pfam PF00293 NUDIX domain 28 95 7.1E-14 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.5E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS23665 ed37267ae5ef37e12f8f6e8a6875e7fc 159 Gene3D G3DSA:3.90.79.10 1 157 5.9E-25 T 29-03-2018 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 SUPERFAMILY SSF50193 1 122 3.01E-50 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 29-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 7.9E-54 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 SMART SM01374 1 122 1.9E-86 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.794 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.8E-57 T 29-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CSW12_RS28035 1eb48b86857d2cdaf3958ecbace7a682 122 Gene3D G3DSA:2.40.150.20 1 122 4.4E-52 T 29-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CSW12_RS26120 82b9449644b7fbfdd6c2bbbac945ed2f 301 Gene3D G3DSA:3.40.50.720 1 292 5.7E-46 T 29-03-2018 CSW12_RS26120 82b9449644b7fbfdd6c2bbbac945ed2f 301 SUPERFAMILY SSF51735 1 287 3.54E-57 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26120 82b9449644b7fbfdd6c2bbbac945ed2f 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 223 3.2E-36 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS24730 2555ccdf2b4d3532afd6bd386f8e260f 270 Gene3D G3DSA:3.40.190.10 122 268 1.1E-48 T 29-03-2018 CSW12_RS24730 2555ccdf2b4d3532afd6bd386f8e260f 270 PIRSF PIRSF002854 1 270 7.2E-101 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS24730 2555ccdf2b4d3532afd6bd386f8e260f 270 Pfam PF03180 NLPA lipoprotein 30 268 1.2E-86 T 29-03-2018 IPR004872 Lipoprotein NlpA family CSW12_RS24730 2555ccdf2b4d3532afd6bd386f8e260f 270 Gene3D G3DSA:3.40.190.10 29 121 6.4E-26 T 29-03-2018 CSW12_RS24730 2555ccdf2b4d3532afd6bd386f8e260f 270 SUPERFAMILY SSF53850 29 269 9.51E-79 T 29-03-2018 CSW12_RS26030 e968938db03e67387b4ab66a96475d4d 399 Pfam PF12704 MacB-like periplasmic core domain 21 238 5.9E-32 T 29-03-2018 IPR025857 MacB-like periplasmic core domain CSW12_RS26030 e968938db03e67387b4ab66a96475d4d 399 Pfam PF02687 FtsX-like permease family 305 392 1.3E-14 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 Pfam PF07729 FCD domain 100 225 1.5E-23 T 29-03-2018 IPR011711 GntR, C-terminal CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 SMART SM00345 15 74 2.5E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 Gene3D G3DSA:1.20.120.530 85 234 1.6E-28 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 Gene3D G3DSA:1.10.10.10 1 84 5.5E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 SMART SM00895 99 226 1.3E-22 T 29-03-2018 IPR011711 GntR, C-terminal CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 SUPERFAMILY SSF46785 6 78 3.39E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.3E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.3E-5 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 SUPERFAMILY SSF48008 95 231 1.52E-29 T 29-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CSW12_RS06050 e95925f7b2132fa825e18ccd62aa23f0 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-18 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS27515 bcea51051ebe7310423c31ad22fa8a26 246 Pfam PF05175 Methyltransferase small domain 33 143 8.9E-8 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CSW12_RS27515 bcea51051ebe7310423c31ad22fa8a26 246 Gene3D G3DSA:3.40.50.150 7 246 6.5E-38 T 29-03-2018 CSW12_RS27515 bcea51051ebe7310423c31ad22fa8a26 246 SUPERFAMILY SSF53335 13 198 6.08E-31 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS24890 52be4360cc7d36fe3756481ac58f67cc 271 Gene3D G3DSA:1.10.720.40 59 96 1.9E-6 T 29-03-2018 IPR011015 LEM/LEM-like domain CSW12_RS24890 52be4360cc7d36fe3756481ac58f67cc 271 Gene3D G3DSA:1.10.720.40 211 243 3.5E-8 T 29-03-2018 IPR011015 LEM/LEM-like domain CSW12_RS24890 52be4360cc7d36fe3756481ac58f67cc 271 Gene3D G3DSA:1.10.720.40 163 183 2.0E-9 T 29-03-2018 IPR011015 LEM/LEM-like domain CSW12_RS24890 52be4360cc7d36fe3756481ac58f67cc 271 Gene3D G3DSA:1.10.720.40 99 137 6.7E-9 T 29-03-2018 IPR011015 LEM/LEM-like domain CSW12_RS24890 52be4360cc7d36fe3756481ac58f67cc 271 Gene3D G3DSA:3.30.2210.10 184 210 1.3E-5 T 29-03-2018 CSW12_RS24890 52be4360cc7d36fe3756481ac58f67cc 271 Gene3D G3DSA:3.30.2210.10 138 162 3.2E-5 T 29-03-2018 CSW12_RS15795 079dc1382bef9db9df1fa6e79ff9a802 436 SUPERFAMILY SSF51905 384 423 7.12E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS15795 079dc1382bef9db9df1fa6e79ff9a802 436 SUPERFAMILY SSF51905 1 305 7.12E-44 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS15795 079dc1382bef9db9df1fa6e79ff9a802 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 376 398 7.3E-5 T 29-03-2018 CSW12_RS15795 079dc1382bef9db9df1fa6e79ff9a802 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.3E-5 T 29-03-2018 CSW12_RS15795 079dc1382bef9db9df1fa6e79ff9a802 436 Gene3D G3DSA:3.50.50.60 2 434 2.8E-34 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS15795 079dc1382bef9db9df1fa6e79ff9a802 436 Pfam PF01593 Flavin containing amine oxidoreductase 13 251 6.3E-23 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CSW12_RS01410 114bf5d002d319c527b0cc9de9f1cb1f 258 SUPERFAMILY SSF53955 61 239 2.22E-69 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS01410 114bf5d002d319c527b0cc9de9f1cb1f 258 Gene3D G3DSA:1.10.3810.10 55 250 2.3E-70 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS01410 114bf5d002d319c527b0cc9de9f1cb1f 258 Pfam PF00912 Transglycosylase 60 217 2.2E-60 T 29-03-2018 IPR001264 Glycosyl transferase, family 51 CSW12_RS21550 0cbf42930d26b0a0bae055a278751dd0 213 Pfam PF01596 O-methyltransferase 40 211 6.7E-35 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CSW12_RS21550 0cbf42930d26b0a0bae055a278751dd0 213 Gene3D G3DSA:3.40.50.150 2 213 1.2E-40 T 29-03-2018 CSW12_RS21550 0cbf42930d26b0a0bae055a278751dd0 213 SUPERFAMILY SSF53335 3 212 2.59E-46 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 Gene3D G3DSA:3.40.50.1360 1 136 3.0E-46 T 29-03-2018 CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 SUPERFAMILY SSF75445 125 203 6.67E-24 T 29-03-2018 CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 216 9.8E-70 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 SUPERFAMILY SSF100950 2 143 1.94E-45 T 29-03-2018 CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 220 32.46 T 29-03-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 Gene3D G3DSA:3.30.70.260 137 200 6.0E-27 T 29-03-2018 CSW12_RS13710 a4daf7078c37320f42aa4d0a425d9620 220 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 3 217 2.5E-91 T 29-03-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CSW12_RS06255 6598dcbb746d500992b5ed75c0da0855 163 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 34 158 3.2E-35 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CSW12_RS06255 6598dcbb746d500992b5ed75c0da0855 163 Gene3D G3DSA:3.30.479.10 11 159 3.5E-41 T 29-03-2018 CSW12_RS06255 6598dcbb746d500992b5ed75c0da0855 163 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 34 123 2.0E-30 T 29-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CSW12_RS06255 6598dcbb746d500992b5ed75c0da0855 163 SUPERFAMILY SSF55620 29 158 2.33E-37 T 29-03-2018 CSW12_RS03865 35c9a8d823949913fdad8b12f66bee25 130 Gene3D G3DSA:3.10.450.50 2 130 8.3E-15 T 29-03-2018 CSW12_RS03865 35c9a8d823949913fdad8b12f66bee25 130 Pfam PF12680 SnoaL-like domain 17 114 3.8E-10 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CSW12_RS03865 35c9a8d823949913fdad8b12f66bee25 130 SUPERFAMILY SSF54427 1 129 6.5E-29 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 SUPERFAMILY SSF81442 14 521 1.7E-181 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 29-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 Gene3D G3DSA:1.10.287.70 535 609 2.3E-14 T 29-03-2018 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 468 5.9E-148 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 519 7.8E-207 T 29-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 191 210 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 425 446 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 7.3E-106 T 29-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08035 cf6792c3f87901fdbc1991ee33535219 620 Gene3D G3DSA:1.20.210.10 12 523 3.5E-198 T 29-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS23180 0a00dee1c0fa33a7afc15119cee18a40 217 SUPERFAMILY SSF53335 25 209 2.67E-30 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS23180 0a00dee1c0fa33a7afc15119cee18a40 217 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 27 210 1.0E-62 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CSW12_RS23180 0a00dee1c0fa33a7afc15119cee18a40 217 Pfam PF02390 Putative methyltransferase 39 206 2.0E-50 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CSW12_RS23180 0a00dee1c0fa33a7afc15119cee18a40 217 Gene3D G3DSA:3.40.50.150 1 211 7.8E-32 T 29-03-2018 CSW12_RS23180 0a00dee1c0fa33a7afc15119cee18a40 217 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.136 T 29-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CSW12_RS07215 f629674358ce6e10eea253c289d46ae6 151 SUPERFAMILY SSF46785 6 142 5.14E-38 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07215 f629674358ce6e10eea253c289d46ae6 151 Gene3D G3DSA:1.10.10.10 1 87 5.0E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07215 f629674358ce6e10eea253c289d46ae6 151 Pfam PF01475 Ferric uptake regulator family 16 136 1.2E-38 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 9.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 9.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 9.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 9.0E-11 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 SMART SM00347 29 129 3.2E-19 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 SUPERFAMILY SSF46785 28 143 5.17E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 Gene3D G3DSA:1.10.10.10 2 133 4.6E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20175 2c6ff6da182c9d6c153f51f1bd76cf25 148 Pfam PF01047 MarR family 39 93 3.7E-13 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS01465 b3dc44e17fddd4431e0bf0c6f26357ca 391 Gene3D G3DSA:3.40.50.410 212 387 8.2E-4 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS01465 b3dc44e17fddd4431e0bf0c6f26357ca 391 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 10 382 9.2E-182 T 29-03-2018 IPR014230 Sporulation protein YhbH CSW12_RS01465 b3dc44e17fddd4431e0bf0c6f26357ca 391 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 387 31.536 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CSW12_RS01465 b3dc44e17fddd4431e0bf0c6f26357ca 391 Pfam PF04285 Protein of unknown function (DUF444) 11 186 6.2E-35 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CSW12_RS01465 b3dc44e17fddd4431e0bf0c6f26357ca 391 Pfam PF04285 Protein of unknown function (DUF444) 192 385 2.2E-68 T 29-03-2018 IPR006698 Uncharacterised protein family UPF0229 CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 Gene3D G3DSA:1.10.10.10 2 95 4.2E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 SMART SM00418 16 95 6.5E-23 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 SUPERFAMILY SSF46785 7 93 8.56E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 Pfam PF12840 Helix-turn-helix domain 17 72 2.6E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 7.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 7.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS01770 605869b686d8a7c6be84f1414f1da6cf 95 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 7.5E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS06775 e40f06d79c2bee7f81f818f998421749 351 SUPERFAMILY SSF55874 220 342 2.23E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06775 e40f06d79c2bee7f81f818f998421749 351 SMART SM00387 252 345 2.6E-10 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06775 e40f06d79c2bee7f81f818f998421749 351 Pfam PF07730 Histidine kinase 149 216 5.0E-20 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS06775 e40f06d79c2bee7f81f818f998421749 351 Gene3D G3DSA:3.30.565.10 213 348 8.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06775 e40f06d79c2bee7f81f818f998421749 351 PIRSF PIRSF037431 5 350 7.5E-136 T 29-03-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 CSW12_RS06775 e40f06d79c2bee7f81f818f998421749 351 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 342 4.6E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS20075 2bf0ca3c83aeb08fe1634b2b18b6d6d9 160 SUPERFAMILY SSF55729 1 126 2.79E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS20075 2bf0ca3c83aeb08fe1634b2b18b6d6d9 160 Gene3D G3DSA:3.40.630.30 1 138 3.4E-16 T 29-03-2018 CSW12_RS20075 2bf0ca3c83aeb08fe1634b2b18b6d6d9 160 Pfam PF00583 Acetyltransferase (GNAT) family 28 118 1.2E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17215 3a09ccdc7ebaf365cd53d78882b6a2b8 236 SUPERFAMILY SSF53800 1 234 1.42E-47 T 29-03-2018 CSW12_RS17215 3a09ccdc7ebaf365cd53d78882b6a2b8 236 Gene3D G3DSA:3.40.50.1400 1 115 3.9E-26 T 29-03-2018 CSW12_RS17215 3a09ccdc7ebaf365cd53d78882b6a2b8 236 Pfam PF01903 CbiX 132 208 6.5E-10 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CSW12_RS17215 3a09ccdc7ebaf365cd53d78882b6a2b8 236 Pfam PF01903 CbiX 9 113 6.9E-29 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CSW12_RS17215 3a09ccdc7ebaf365cd53d78882b6a2b8 236 Gene3D G3DSA:3.40.50.1400 116 216 6.3E-13 T 29-03-2018 CSW12_RS28480 1a2440a5a53794ba856ec29c8a40d3b0 46 Pfam PF14142 YrzO-like protein 1 44 3.0E-31 T 29-03-2018 IPR025417 YrzO-like protein CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 SUPERFAMILY SSF53474 3 267 9.25E-59 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 Pfam PF00561 alpha/beta hydrolase fold 20 254 3.0E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 PRINTS PR00412 Epoxide hydrolase signature 25 43 8.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 PRINTS PR00412 Epoxide hydrolase signature 243 265 8.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 PRINTS PR00412 Epoxide hydrolase signature 104 117 8.9E-6 T 29-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 Gene3D G3DSA:3.40.50.1820 8 268 3.9E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 19 267 2.4E-92 T 29-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 267 37.594 T 29-03-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 6.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS24020 476a7080425333c535a1a47bf25dd98f 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.2E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS29525 8bf892187fc66393d8e12aeb2c1a2522 139 Gene3D G3DSA:1.20.1550.10 1 120 4.8E-19 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CSW12_RS29525 8bf892187fc66393d8e12aeb2c1a2522 139 Pfam PF02600 Disulfide bond formation protein DsbB 4 100 3.4E-10 T 29-03-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CSW12_RS29525 8bf892187fc66393d8e12aeb2c1a2522 139 SUPERFAMILY SSF158442 2 123 2.22E-25 T 29-03-2018 IPR023380 Disulphide bond formation protein DsbB-like domain CSW12_RS29525 8bf892187fc66393d8e12aeb2c1a2522 139 PIRSF PIRSF036659 1 132 1.8E-48 T 29-03-2018 IPR012187 Disulphide bond formation protein BdbC CSW12_RS21060 9cc67b29847180137d774fa010f936cb 235 Gene3D G3DSA:3.40.50.150 1 165 3.6E-16 T 29-03-2018 CSW12_RS21060 9cc67b29847180137d774fa010f936cb 235 PIRSF PIRSF018637 4 235 1.8E-82 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CSW12_RS21060 9cc67b29847180137d774fa010f936cb 235 SUPERFAMILY SSF53335 10 106 1.57E-7 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS21060 9cc67b29847180137d774fa010f936cb 235 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 231 3.3E-72 T 29-03-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 3 18 1.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 23 32 1.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 PRINTS PR00050 Cold shock protein signature 38 56 1.5E-18 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 Pfam PF00313 'Cold-shock' DNA-binding domain 1 64 1.0E-30 T 29-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 SMART SM00357 2 65 1.7E-30 T 29-03-2018 IPR011129 Cold shock domain GO:0003676 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 Gene3D G3DSA:2.40.50.140 1 65 1.2E-27 T 29-03-2018 CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 32 - T 29-03-2018 IPR019844 Cold-shock conserved site CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 SUPERFAMILY SSF50249 1 64 4.63E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS19565 ed6a91e3e4f24ef594cc16cead55dd1e 65 PIRSF PIRSF002599 1 65 3.1E-24 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS26110 a549d451a99dcd5630a379feacdf813b 423 SUPERFAMILY SSF53756 5 83 1.78E-41 T 29-03-2018 CSW12_RS26110 a549d451a99dcd5630a379feacdf813b 423 SUPERFAMILY SSF53756 129 402 1.78E-41 T 29-03-2018 CSW12_RS26110 a549d451a99dcd5630a379feacdf813b 423 Pfam PF00534 Glycosyl transferases group 1 235 393 4.5E-32 T 29-03-2018 IPR001296 Glycosyl transferase, family 1 CSW12_RS26110 a549d451a99dcd5630a379feacdf813b 423 Gene3D G3DSA:3.40.50.2000 13 412 9.7E-36 T 29-03-2018 CSW12_RS21710 6852c90e48e53be220f1fafc0dccd432 215 Pfam PF04239 Protein of unknown function (DUF421) 88 193 2.8E-37 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CSW12_RS21710 6852c90e48e53be220f1fafc0dccd432 215 Gene3D G3DSA:3.30.240.20 160 214 3.1E-10 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS21710 6852c90e48e53be220f1fafc0dccd432 215 Gene3D G3DSA:3.30.240.20 81 150 2.0E-25 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS16740 693f9690192dfdb2e51ed0dbb495be9e 301 Gene3D G3DSA:3.40.50.850 22 301 6.9E-31 T 29-03-2018 CSW12_RS16740 693f9690192dfdb2e51ed0dbb495be9e 301 SUPERFAMILY SSF52499 155 287 3.53E-10 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS16740 693f9690192dfdb2e51ed0dbb495be9e 301 SUPERFAMILY SSF52499 43 106 3.53E-10 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS18930 8ba7107a6d77515b9504844d4023bc46 137 PIRSF PIRSF019455 13 137 1.7E-21 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CSW12_RS18930 8ba7107a6d77515b9504844d4023bc46 137 Pfam PF03965 Penicillinase repressor 18 132 5.9E-28 T 29-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CSW12_RS18930 8ba7107a6d77515b9504844d4023bc46 137 Gene3D G3DSA:1.10.10.10 19 81 3.2E-17 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18930 8ba7107a6d77515b9504844d4023bc46 137 SUPERFAMILY SSF46785 17 134 1.59E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13910 32fccd19b625d92cf177586885c359f5 279 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 17 279 42.115 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CSW12_RS13910 32fccd19b625d92cf177586885c359f5 279 SUPERFAMILY SSF140959 22 279 1.19E-103 T 29-03-2018 CSW12_RS13910 32fccd19b625d92cf177586885c359f5 279 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 16 279 3.4E-134 T 29-03-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 CSW12_RS13910 32fccd19b625d92cf177586885c359f5 279 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 278 2.4E-69 T 29-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CSW12_RS27555 732305feb26a92a10d4ab29f491ea2f1 287 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 3 276 4.0E-152 T 29-03-2018 IPR008764 Peptidase U57, YabG CSW12_RS27555 732305feb26a92a10d4ab29f491ea2f1 287 PIRSF PIRSF011575 2 286 9.9E-110 T 29-03-2018 IPR008764 Peptidase U57, YabG CSW12_RS27555 732305feb26a92a10d4ab29f491ea2f1 287 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 282 1.1E-138 T 29-03-2018 IPR008764 Peptidase U57, YabG CSW12_RS27555 732305feb26a92a10d4ab29f491ea2f1 287 Pfam PF05582 YabG peptidase U57 5 281 6.7E-112 T 29-03-2018 IPR008764 Peptidase U57, YabG CSW12_RS04645 0259c73f6ebaabe280573cbdee7cf7f2 158 Pfam PF03703 Bacterial PH domain 72 147 6.3E-17 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS16895 bcf7f9964558d7916a3ab35397ddb092 236 SMART SM00382 27 214 1.6E-4 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS16895 bcf7f9964558d7916a3ab35397ddb092 236 SUPERFAMILY SSF52540 17 211 2.27E-46 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS16895 bcf7f9964558d7916a3ab35397ddb092 236 Gene3D G3DSA:3.40.50.300 2 220 3.1E-47 T 29-03-2018 CSW12_RS16895 bcf7f9964558d7916a3ab35397ddb092 236 Pfam PF00005 ABC transporter 19 152 2.2E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS05960 0992e6898ead6d1f8518ef00d9df4f27 795 SUPERFAMILY SSF55486 263 304 6.33E-17 T 29-03-2018 CSW12_RS05960 0992e6898ead6d1f8518ef00d9df4f27 795 SUPERFAMILY SSF55486 354 429 6.33E-17 T 29-03-2018 CSW12_RS05960 0992e6898ead6d1f8518ef00d9df4f27 795 Pfam PF05547 Immune inhibitor A peptidase M6 150 791 0.0 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS05960 0992e6898ead6d1f8518ef00d9df4f27 795 Gene3D G3DSA:2.60.120.260 385 608 9.4E-15 T 29-03-2018 IPR008979 Galactose-binding domain-like CSW12_RS05960 0992e6898ead6d1f8518ef00d9df4f27 795 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 183 492 5.0E-87 T 29-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CSW12_RS05960 0992e6898ead6d1f8518ef00d9df4f27 795 PIRSF PIRSF007519 1 795 0.0 T 29-03-2018 IPR012300 Peptidase M6, InhA CSW12_RS24940 3ecf9b81a673a787b843eda842b925b9 73 Pfam PF01381 Helix-turn-helix 7 61 3.7E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS24940 3ecf9b81a673a787b843eda842b925b9 73 SUPERFAMILY SSF47413 1 69 4.02E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS24940 3ecf9b81a673a787b843eda842b925b9 73 Gene3D G3DSA:1.10.3100.10 2 73 1.3E-17 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS24940 3ecf9b81a673a787b843eda842b925b9 73 SMART SM00530 6 61 3.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS19765 a62df4e48e8693824c5d54544716dfb1 157 SUPERFAMILY SSF55729 1 150 9.53E-21 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS19765 a62df4e48e8693824c5d54544716dfb1 157 Pfam PF00583 Acetyltransferase (GNAT) family 33 130 5.3E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS19765 a62df4e48e8693824c5d54544716dfb1 157 Gene3D G3DSA:3.40.630.30 4 145 6.9E-17 T 29-03-2018 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 Gene3D G3DSA:1.10.1740.10 1 78 8.7E-20 T 29-03-2018 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 SUPERFAMILY SSF88659 103 158 2.06E-12 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 Pfam PF04542 Sigma-70 region 2 10 76 6.2E-16 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 SUPERFAMILY SSF88946 4 92 2.75E-21 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 157 1.8E-24 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 Gene3D G3DSA:1.10.10.10 90 161 8.1E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 Pfam PF08281 Sigma-70, region 4 108 156 2.0E-15 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04835 cb39390e53299948699b59e5c4d02d01 161 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 6 160 3.6E-70 T 29-03-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS04865 4dfaa8312f73e7e80c50f34042494de1 284 Pfam PF02517 CAAX protease self-immunity 129 211 7.9E-17 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS25410 c2f6306a249d40571cbabd6104d7b76f 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 9.2E-22 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 CSW12_RS13475 5752b2316204a3afcd6b371fb26ad17b 102 Pfam PF10850 Protein of unknown function (DUF2653) 1 88 1.5E-38 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD CSW12_RS13475 5752b2316204a3afcd6b371fb26ad17b 102 ProDom PD068665 YXCD 1 102 2.0E-51 T 29-03-2018 IPR020516 Uncharacterised protein family YxcD CSW12_RS11515 796b21be9c0a10db7e5d58cc27ee4398 235 SUPERFAMILY SSF48371 1 235 9.78E-69 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS11515 796b21be9c0a10db7e5d58cc27ee4398 235 Gene3D G3DSA:1.20.1660.10 4 98 1.4E-4 T 29-03-2018 CSW12_RS11515 796b21be9c0a10db7e5d58cc27ee4398 235 Pfam PF08713 DNA alkylation repair enzyme 6 215 6.3E-23 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CSW12_RS14395 84d3c4816525ac9f6158c394324f381c 268 Gene3D G3DSA:3.30.1180.10 151 268 2.9E-23 T 29-03-2018 CSW12_RS14395 84d3c4816525ac9f6158c394324f381c 268 SUPERFAMILY SSF82549 1 268 1.12E-61 T 29-03-2018 CSW12_RS14395 84d3c4816525ac9f6158c394324f381c 268 Gene3D G3DSA:3.40.50.10170 1 149 3.7E-33 T 29-03-2018 CSW12_RS14395 84d3c4816525ac9f6158c394324f381c 268 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 7 268 9.3E-58 T 29-03-2018 IPR003797 DegV CSW12_RS14395 84d3c4816525ac9f6158c394324f381c 268 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 268 8.6E-53 T 29-03-2018 IPR003797 DegV CSW12_RS06210 c8864fad3672189760820277e6ec76d7 256 SUPERFAMILY SSF88713 30 247 2.0E-65 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS06210 c8864fad3672189760820277e6ec76d7 256 Gene3D G3DSA:3.20.20.370 21 251 1.1E-76 T 29-03-2018 CSW12_RS06210 c8864fad3672189760820277e6ec76d7 256 Pfam PF04748 Divergent polysaccharide deacetylase 33 247 4.4E-71 T 29-03-2018 IPR006837 Divergent polysaccharide deacetylase CSW12_RS03180 848877391f434a1f58e2b251bcff4ebb 431 Pfam PF10117 McrBC 5-methylcytosine restriction system component 54 372 1.0E-72 T 29-03-2018 IPR019292 5-methylcytosine restriction system component CSW12_RS11340 a0a28d6aa8c970bd06314e9b958effa5 359 SUPERFAMILY SSF56112 17 291 2.98E-8 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS11340 a0a28d6aa8c970bd06314e9b958effa5 359 Gene3D G3DSA:3.90.1200.10 105 255 0.0022 T 29-03-2018 CSW12_RS20430 0904fe8d5fab0e62770d3859b8ec0806 508 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 152 297 3.5E-6 T 29-03-2018 CSW12_RS15010 5f14b0f861d861e0e8bf9d5744471900 513 SUPERFAMILY SSF52096 8 253 1.15E-67 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS15010 5f14b0f861d861e0e8bf9d5744471900 513 SUPERFAMILY SSF52096 215 490 4.84E-81 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS15010 5f14b0f861d861e0e8bf9d5744471900 513 Gene3D G3DSA:3.90.226.10 252 512 2.6E-68 T 29-03-2018 CSW12_RS15010 5f14b0f861d861e0e8bf9d5744471900 513 Gene3D G3DSA:3.90.226.10 1 251 8.8E-63 T 29-03-2018 CSW12_RS15010 5f14b0f861d861e0e8bf9d5744471900 513 Pfam PF01039 Carboxyl transferase domain 30 510 3.2E-158 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 Gene3D G3DSA:1.10.10.10 1 129 3.9E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 Pfam PF01047 MarR family 36 91 5.2E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 SMART SM00347 26 129 2.1E-15 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 SUPERFAMILY SSF46785 6 147 2.36E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 6.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 6.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 6.5E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15715 a380671acbf7f1ada13b7c946fbee1a5 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CSW12_RS00330 ed1c99837a55539354ca6e9e939c49f6 211 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 12 193 6.4E-11 T 29-03-2018 IPR006490 Phage major tail protein, phi13 family CSW12_RS02055 0e439d09d6f924ec0c2a600195a3e9e1 140 Gene3D G3DSA:1.10.260.40 1 133 3.6E-16 T 29-03-2018 CSW12_RS02055 0e439d09d6f924ec0c2a600195a3e9e1 140 SUPERFAMILY SSF47413 1 63 4.22E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02055 0e439d09d6f924ec0c2a600195a3e9e1 140 SMART SM00530 6 59 7.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS02055 0e439d09d6f924ec0c2a600195a3e9e1 140 Pfam PF01381 Helix-turn-helix 7 59 3.9E-10 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS11845 74f44de0981214a11cdb07afdbf0333a 192 Pfam PF13796 Putative sensor 11 186 1.3E-22 T 29-03-2018 IPR025828 Putative sensor domain CSW12_RS12395 e205e2a81cc74da944d6ab0cc9fb039b 256 Pfam PF08713 DNA alkylation repair enzyme 125 241 5.5E-10 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CSW12_RS12395 e205e2a81cc74da944d6ab0cc9fb039b 256 Gene3D G3DSA:1.25.40.290 138 249 5.1E-19 T 29-03-2018 CSW12_RS12395 e205e2a81cc74da944d6ab0cc9fb039b 256 SUPERFAMILY SSF48371 10 246 3.99E-44 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS00885 381570eca0760936bd543df78f37ad46 340 PRINTS PR01228 Eggshell protein signature 142 152 1.9E-6 T 29-03-2018 CSW12_RS00885 381570eca0760936bd543df78f37ad46 340 PRINTS PR01228 Eggshell protein signature 8 24 1.9E-6 T 29-03-2018 CSW12_RS00885 381570eca0760936bd543df78f37ad46 340 PRINTS PR01228 Eggshell protein signature 115 130 1.9E-6 T 29-03-2018 CSW12_RS00885 381570eca0760936bd543df78f37ad46 340 PRINTS PR01228 Eggshell protein signature 168 186 1.9E-6 T 29-03-2018 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 Pfam PF00501 AMP-binding enzyme 55 462 4.1E-92 T 29-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 Gene3D G3DSA:2.30.38.10 371 455 4.7E-22 T 29-03-2018 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 Gene3D G3DSA:3.40.50.980 218 370 8.0E-44 T 29-03-2018 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 Gene3D G3DSA:3.30.300.30 458 570 9.4E-27 T 29-03-2018 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 29-03-2018 IPR020845 AMP-binding, conserved site CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 Gene3D G3DSA:3.40.50.980 40 217 9.6E-37 T 29-03-2018 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 SUPERFAMILY SSF56801 21 562 1.83E-162 T 29-03-2018 CSW12_RS22970 aa0af714160cfdbd8891ecd5be198e3e 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 4.7E-24 T 29-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CSW12_RS27035 2c132e4976dd12da7032fe710910ce1f 94 SUPERFAMILY SSF53098 3 61 1.23E-7 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS27035 2c132e4976dd12da7032fe710910ce1f 94 Pfam PF00665 Integrase core domain 4 64 4.6E-8 T 29-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CSW12_RS27035 2c132e4976dd12da7032fe710910ce1f 94 Gene3D G3DSA:3.30.420.10 1 80 4.4E-8 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 SMART SM00345 18 77 2.1E-22 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 SUPERFAMILY SSF46785 11 84 7.45E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 Gene3D G3DSA:1.10.10.10 3 79 2.0E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 SUPERFAMILY SSF53383 97 465 7.17E-88 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 9.1E-20 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.8E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.8E-7 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 Gene3D G3DSA:3.90.1150.10 369 467 6.7E-17 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 Pfam PF00155 Aminotransferase class I and II 107 459 8.1E-24 T 29-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CSW12_RS28925 8e86f1a57de9d44d65d47aa1d3fb3bb1 470 Gene3D G3DSA:3.40.640.10 126 368 1.3E-42 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS18945 e4f64e3f3cd2cbcd648f532b18465f94 469 TIGRFAM TIGR00797 matE: MATE efflux family protein 34 437 8.9E-97 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS18945 e4f64e3f3cd2cbcd648f532b18465f94 469 Pfam PF01554 MatE 34 194 6.1E-37 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS18945 e4f64e3f3cd2cbcd648f532b18465f94 469 Pfam PF01554 MatE 263 423 1.7E-32 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS18945 e4f64e3f3cd2cbcd648f532b18465f94 469 PIRSF PIRSF006603 7 468 1.0E-133 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS17490 b6fdd422316d3263c8a1a7be8399d162 237 Pfam PF13649 Methyltransferase domain 46 137 1.8E-16 T 29-03-2018 CSW12_RS17490 b6fdd422316d3263c8a1a7be8399d162 237 SUPERFAMILY SSF53335 10 228 2.81E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS17490 b6fdd422316d3263c8a1a7be8399d162 237 Gene3D G3DSA:3.40.50.150 2 236 2.0E-29 T 29-03-2018 CSW12_RS00650 aaa637e22890f4256521f7bed56ea680 369 Gene3D G3DSA:3.40.50.300 12 47 0.28 T 29-03-2018 CSW12_RS00650 aaa637e22890f4256521f7bed56ea680 369 Gene3D G3DSA:3.40.50.300 48 192 5.1E-4 T 29-03-2018 CSW12_RS00650 aaa637e22890f4256521f7bed56ea680 369 Gene3D G3DSA:3.40.50.300 216 367 3.7E-7 T 29-03-2018 CSW12_RS00650 aaa637e22890f4256521f7bed56ea680 369 SUPERFAMILY SSF52540 210 292 7.6E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00650 aaa637e22890f4256521f7bed56ea680 369 SUPERFAMILY SSF52540 28 66 9.42E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00650 aaa637e22890f4256521f7bed56ea680 369 SUPERFAMILY SSF52540 125 172 9.42E-10 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS28180 32f4c145540e805b9f06c0709292325f 203 SMART SM01251 17 196 2.0E-119 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CSW12_RS28180 32f4c145540e805b9f06c0709292325f 203 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 195 2.4E-79 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CSW12_RS28180 32f4c145540e805b9f06c0709292325f 203 PIRSF PIRSF029886 1 199 1.2E-78 T 29-03-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 CSW12_RS31065 645f357ed557ee4a5980ff0d471baf62 164 PIRSF PIRSF002070 1 153 9.5E-40 T 29-03-2018 CSW12_RS31065 645f357ed557ee4a5980ff0d471baf62 164 SUPERFAMILY SSF50249 1 164 7.2E-54 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS31065 645f357ed557ee4a5980ff0d471baf62 164 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 164 1.1E-46 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS31065 645f357ed557ee4a5980ff0d471baf62 164 Hamap MF_00984 Single-stranded DNA-binding protein. 3 107 35.925 T 29-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CSW12_RS31065 645f357ed557ee4a5980ff0d471baf62 164 Pfam PF00436 Single-strand binding protein family 3 103 1.1E-37 T 29-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CSW12_RS31065 645f357ed557ee4a5980ff0d471baf62 164 Gene3D G3DSA:2.40.50.140 1 121 4.4E-41 T 29-03-2018 CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 SMART SM00418 21 100 1.1E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 8.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 8.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 8.9E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 SUPERFAMILY SSF46785 7 98 5.55E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 Gene3D G3DSA:1.10.10.10 7 99 1.4E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30130 171dc1f34a4731780cebdb25658dcf32 100 Pfam PF12840 Helix-turn-helix domain 20 79 4.2E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 SUPERFAMILY SSF88946 8 73 4.58E-11 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 Gene3D G3DSA:1.10.1740.10 2 74 7.1E-12 T 29-03-2018 CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 Gene3D G3DSA:1.10.10.10 98 156 2.4E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 Pfam PF04545 Sigma-70, region 4 104 152 1.5E-5 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 152 2.4E-19 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 SUPERFAMILY SSF88659 92 155 1.74E-11 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS26020 bb37e01a5c0793c865c82266db6bd51b 156 Pfam PF04542 Sigma-70 region 2 24 75 1.5E-9 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS02160 4eb032b41f82695d5196b935e1bfb1cb 542 Pfam PF03354 Phage Terminase 55 525 1.1E-38 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CSW12_RS29970 700fd1dcf370275692b204116c0441ab 235 Pfam PF13610 DDE domain 74 212 4.6E-50 T 29-03-2018 IPR032874 DDE domain CSW12_RS29970 700fd1dcf370275692b204116c0441ab 235 SUPERFAMILY SSF53098 70 191 3.03E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29970 700fd1dcf370275692b204116c0441ab 235 Gene3D G3DSA:3.30.420.10 64 217 7.5E-18 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS18825 f714cde6a969f49b9a20a17983414a0a 247 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 237 2.5E-94 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CSW12_RS18825 f714cde6a969f49b9a20a17983414a0a 247 SUPERFAMILY SSF53633 3 237 4.58E-59 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS18825 f714cde6a969f49b9a20a17983414a0a 247 Pfam PF00696 Amino acid kinase family 5 216 2.9E-24 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS18825 f714cde6a969f49b9a20a17983414a0a 247 Gene3D G3DSA:3.40.1160.10 1 238 8.6E-34 T 29-03-2018 CSW12_RS18825 f714cde6a969f49b9a20a17983414a0a 247 PIRSF PIRSF005650 1 247 4.3E-82 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CSW12_RS18825 f714cde6a969f49b9a20a17983414a0a 247 Hamap MF_01220_B Uridylate kinase [pyrH]. 2 237 36.773 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CSW12_RS14150 ab1e7b9c40ca53df9a5bcbe2e62c2201 476 Gene3D G3DSA:2.120.10.30 5 476 7.9E-34 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CSW12_RS14150 ab1e7b9c40ca53df9a5bcbe2e62c2201 476 Pfam PF07995 Glucose / Sorbosone dehydrogenase 77 277 4.3E-11 T 29-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CSW12_RS14150 ab1e7b9c40ca53df9a5bcbe2e62c2201 476 SUPERFAMILY SSF50952 61 101 9.02E-12 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CSW12_RS14150 ab1e7b9c40ca53df9a5bcbe2e62c2201 476 SUPERFAMILY SSF50952 136 316 9.02E-12 T 29-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CSW12_RS06345 53128b024c1e5fa027083a9dc7fda814 300 SUPERFAMILY SSF52540 2 233 1.78E-62 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS06345 53128b024c1e5fa027083a9dc7fda814 300 SMART SM00382 30 212 9.7E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS06345 53128b024c1e5fa027083a9dc7fda814 300 Pfam PF00005 ABC transporter 22 163 3.2E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS06345 53128b024c1e5fa027083a9dc7fda814 300 Gene3D G3DSA:3.40.50.300 2 269 2.3E-62 T 29-03-2018 CSW12_RS06345 53128b024c1e5fa027083a9dc7fda814 300 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS10205 593a262cf06c8990001e22592d91323e 788 Gene3D G3DSA:2.60.20.10 313 493 0.02 T 29-03-2018 CSW12_RS10205 593a262cf06c8990001e22592d91323e 788 Pfam PF11958 Domain of unknown function (DUF3472) 105 263 1.2E-27 T 29-03-2018 IPR021862 Protein of unknown function DUF3472 CSW12_RS10205 593a262cf06c8990001e22592d91323e 788 Pfam PF03272 Putative mucin or carbohydrate-binding module 527 645 9.3E-26 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS10205 593a262cf06c8990001e22592d91323e 788 Pfam PF03272 Putative mucin or carbohydrate-binding module 666 784 2.7E-24 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS10205 593a262cf06c8990001e22592d91323e 788 Pfam PF03272 Putative mucin or carbohydrate-binding module 393 506 1.5E-28 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS09055 c110573d4808a01857686f16364f3000 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS09055 c110573d4808a01857686f16364f3000 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS09055 c110573d4808a01857686f16364f3000 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 1.8E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS09055 c110573d4808a01857686f16364f3000 271 Gene3D G3DSA:3.40.50.1820 2 270 9.2E-32 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS09055 c110573d4808a01857686f16364f3000 271 SUPERFAMILY SSF53474 5 264 2.32E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS09055 c110573d4808a01857686f16364f3000 271 Pfam PF12146 Serine aminopeptidase, S33 21 132 2.9E-8 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS06905 7a12acca1493d548e7fe4599846ebb5e 235 SUPERFAMILY SSF53167 2 233 1.83E-94 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS06905 7a12acca1493d548e7fe4599846ebb5e 235 Pfam PF01048 Phosphorylase superfamily 16 222 1.8E-43 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS06905 7a12acca1493d548e7fe4599846ebb5e 235 Gene3D G3DSA:3.40.50.1580 8 235 4.6E-58 T 29-03-2018 CSW12_RS06905 7a12acca1493d548e7fe4599846ebb5e 235 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 234 49.249 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CSW12_RS06905 7a12acca1493d548e7fe4599846ebb5e 235 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 233 4.8E-109 T 29-03-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CSW12_RS06905 7a12acca1493d548e7fe4599846ebb5e 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 29-03-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS08365 3b537d574269c331a9c89e660bfd950b 122 Pfam PF14037 YoqO-like protein 4 118 3.1E-47 T 29-03-2018 IPR025621 YoqO-like protein CSW12_RS18510 4b680b5965e8102733ca0ce5ed27ba30 290 SUPERFAMILY SSF140453 3 93 1.03E-12 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS18510 4b680b5965e8102733ca0ce5ed27ba30 290 Gene3D G3DSA:1.10.287.850 1 90 2.0E-7 T 29-03-2018 CSW12_RS18510 4b680b5965e8102733ca0ce5ed27ba30 290 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 91 6.2E-15 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS18510 4b680b5965e8102733ca0ce5ed27ba30 290 Pfam PF06013 Proteins of 100 residues with WXG 4 87 9.2E-11 T 29-03-2018 IPR010310 Type VII secretion system ESAT-6-like CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 SUPERFAMILY SSF47336 2 77 1.09E-21 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 Gene3D G3DSA:1.10.1200.10 2 77 9.2E-25 T 29-03-2018 CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 29-03-2018 IPR006162 Phosphopantetheine attachment site CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 77 2.0E-13 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 Pfam PF00550 Phosphopantetheine attachment site 6 73 7.9E-15 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.155 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CSW12_RS08525 1ae876407cd1c445ecb71bd2b1272e28 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.2E-33 T 29-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CSW12_RS04265 d2643e1d7b2ff4f4c0f08b75ea8efd0e 83 Pfam PF04226 Transglycosylase associated protein 33 78 4.9E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CSW12_RS31215 8944cd5a396033bab60df3ba6b9a3d8e 342 Pfam PF03318 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 96 305 1.9E-10 T 29-03-2018 IPR004991 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 CSW12_RS31215 8944cd5a396033bab60df3ba6b9a3d8e 342 Gene3D G3DSA:2.170.15.10 87 306 3.5E-13 T 29-03-2018 CSW12_RS31215 8944cd5a396033bab60df3ba6b9a3d8e 342 SUPERFAMILY SSF56973 87 308 1.44E-10 T 29-03-2018 CSW12_RS30540 8944cd5a396033bab60df3ba6b9a3d8e 342 Pfam PF03318 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 96 305 1.9E-10 T 29-03-2018 IPR004991 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 CSW12_RS30540 8944cd5a396033bab60df3ba6b9a3d8e 342 Gene3D G3DSA:2.170.15.10 87 306 3.5E-13 T 29-03-2018 CSW12_RS30540 8944cd5a396033bab60df3ba6b9a3d8e 342 SUPERFAMILY SSF56973 87 308 1.44E-10 T 29-03-2018 CSW12_RS02300 4cb65683a1211e1aebcd7346dc4df19d 311 Gene3D G3DSA:1.10.3470.10 30 309 1.0E-40 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS02300 4cb65683a1211e1aebcd7346dc4df19d 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 303 8.0E-53 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS30000 7856220d5a6f8c4c949233f985cb7486 105 Gene3D G3DSA:1.10.10.10 43 102 2.1E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24340 397d4de0b2129f6eaa6d92ff3bfbab8c 444 Pfam PF03600 Citrate transporter 27 385 5.4E-50 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CSW12_RS24340 397d4de0b2129f6eaa6d92ff3bfbab8c 444 PRINTS PR00758 Arsenical pump membrane protein signature 113 137 1.5E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS24340 397d4de0b2129f6eaa6d92ff3bfbab8c 444 PRINTS PR00758 Arsenical pump membrane protein signature 289 313 1.5E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS24340 397d4de0b2129f6eaa6d92ff3bfbab8c 444 PRINTS PR00758 Arsenical pump membrane protein signature 230 255 1.5E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS24340 397d4de0b2129f6eaa6d92ff3bfbab8c 444 PRINTS PR00758 Arsenical pump membrane protein signature 381 406 1.5E-10 T 29-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CSW12_RS08270 857012e78a844f62ed8a2667a006cb83 255 SMART SM00363 179 241 1.5E-11 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS08270 857012e78a844f62ed8a2667a006cb83 255 Pfam PF01479 S4 domain 180 224 6.8E-8 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS08270 857012e78a844f62ed8a2667a006cb83 255 Gene3D G3DSA:3.10.290.10 178 231 9.0E-13 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS08270 857012e78a844f62ed8a2667a006cb83 255 SUPERFAMILY SSF55174 176 252 1.7E-38 T 29-03-2018 CSW12_RS08270 857012e78a844f62ed8a2667a006cb83 255 SUPERFAMILY SSF55174 34 124 1.7E-38 T 29-03-2018 CSW12_RS28815 edb194459c5ca8463aaf2250d5b013b1 230 SUPERFAMILY SSF53067 1 101 1.12E-28 T 29-03-2018 CSW12_RS28815 edb194459c5ca8463aaf2250d5b013b1 230 Pfam PF00814 Glycoprotease family 32 224 5.6E-37 T 29-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CSW12_RS28815 edb194459c5ca8463aaf2250d5b013b1 230 SUPERFAMILY SSF53067 108 214 3.75E-15 T 29-03-2018 CSW12_RS28815 edb194459c5ca8463aaf2250d5b013b1 230 Gene3D G3DSA:3.30.420.40 1 138 1.2E-34 T 29-03-2018 CSW12_RS28815 edb194459c5ca8463aaf2250d5b013b1 230 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 3.2E-56 T 29-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CSW12_RS13335 a1ba3f158e0e7e41bca06a93611e06e1 527 SUPERFAMILY SSF55486 70 526 7.64E-72 T 29-03-2018 CSW12_RS13335 a1ba3f158e0e7e41bca06a93611e06e1 527 Gene3D G3DSA:1.10.1370.10 56 504 5.5E-4 T 29-03-2018 CSW12_RS13335 a1ba3f158e0e7e41bca06a93611e06e1 527 Pfam PF01432 Peptidase family M3 264 498 1.9E-12 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CSW12_RS13870 d13364de20350c8e79bce9a75fe97860 365 Pfam PF03022 Major royal jelly protein 80 340 8.3E-34 T 29-03-2018 IPR017996 Major royal jelly protein/protein yellow CSW12_RS13870 d13364de20350c8e79bce9a75fe97860 365 SUPERFAMILY SSF63829 208 333 8.5E-22 T 29-03-2018 CSW12_RS13870 d13364de20350c8e79bce9a75fe97860 365 SUPERFAMILY SSF63829 23 182 8.5E-22 T 29-03-2018 CSW12_RS13870 d13364de20350c8e79bce9a75fe97860 365 Gene3D G3DSA:2.120.10.30 8 364 3.2E-46 T 29-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CSW12_RS07470 1fd1d086de919c71fdb37698732d84ac 371 SUPERFAMILY SSF56601 54 358 3.87E-76 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS07470 1fd1d086de919c71fdb37698732d84ac 371 Pfam PF00144 Beta-lactamase 72 354 1.4E-56 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS07470 1fd1d086de919c71fdb37698732d84ac 371 Gene3D G3DSA:3.40.710.10 36 371 2.4E-73 T 29-03-2018 CSW12_RS11465 b3d63f7c05fab62e31b86d5f14d88ba9 419 Pfam PF00144 Beta-lactamase 109 395 1.8E-37 T 29-03-2018 IPR001466 Beta-lactamase-related CSW12_RS11465 b3d63f7c05fab62e31b86d5f14d88ba9 419 Gene3D G3DSA:3.40.710.10 56 417 2.1E-52 T 29-03-2018 CSW12_RS11465 b3d63f7c05fab62e31b86d5f14d88ba9 419 SUPERFAMILY SSF56601 9 410 7.13E-82 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS12650 f065b1d999c230489b665e3539732e72 193 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 19 155 2.4E-6 T 29-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CSW12_RS12650 f065b1d999c230489b665e3539732e72 193 SUPERFAMILY SSF52540 15 192 2.68E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12650 f065b1d999c230489b665e3539732e72 193 Gene3D G3DSA:3.40.50.300 13 193 7.1E-19 T 29-03-2018 CSW12_RS06015 6644e1616a3843b066aab45ab7042845 275 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 152 273 3.7E-62 T 29-03-2018 IPR014258 CAP domain, YkwD-like CSW12_RS06015 6644e1616a3843b066aab45ab7042845 275 SUPERFAMILY SSF55797 151 272 2.88E-28 T 29-03-2018 IPR014044 CAP domain CSW12_RS06015 6644e1616a3843b066aab45ab7042845 275 Gene3D G3DSA:3.40.33.10 146 274 2.1E-22 T 29-03-2018 IPR014044 CAP domain CSW12_RS06015 6644e1616a3843b066aab45ab7042845 275 Pfam PF00188 Cysteine-rich secretory protein family 160 272 1.4E-24 T 29-03-2018 IPR014044 CAP domain CSW12_RS00345 b34f300637a0540646f3f8da710cec90 1174 Gene3D G3DSA:1.10.287.700 837 916 7.0E-6 T 29-03-2018 CSW12_RS00345 b34f300637a0540646f3f8da710cec90 1174 Gene3D G3DSA:1.20.5.1230 529 808 2.0E-30 T 29-03-2018 CSW12_RS00345 b34f300637a0540646f3f8da710cec90 1174 Gene3D G3DSA:1.20.5.1230 926 1044 1.1E-11 T 29-03-2018 CSW12_RS00345 b34f300637a0540646f3f8da710cec90 1174 Pfam PF10145 Phage-related minor tail protein 321 517 5.1E-25 T 29-03-2018 IPR010090 Phage tail tape measure protein CSW12_RS00345 b34f300637a0540646f3f8da710cec90 1174 Gene3D G3DSA:1.20.1170.10 13 300 2.7E-4 T 29-03-2018 CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 Pfam PF03466 LysR substrate binding domain 86 282 3.6E-37 T 29-03-2018 IPR005119 LysR, substrate-binding CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 SUPERFAMILY SSF53850 85 282 2.95E-33 T 29-03-2018 CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.8E-16 T 29-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 Gene3D G3DSA:3.40.190.10 84 167 4.0E-14 T 29-03-2018 CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 Gene3D G3DSA:3.40.190.10 168 256 9.2E-15 T 29-03-2018 CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 Gene3D G3DSA:1.10.10.10 1 83 1.6E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00085 d1963136ee00c06e71a50e4078701555 289 SUPERFAMILY SSF46785 1 110 6.54E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 Pfam PF00563 EAL domain 12 233 2.0E-29 T 29-03-2018 IPR001633 EAL domain CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 SUPERFAMILY SSF141868 4 256 9.68E-42 T 29-03-2018 IPR001633 EAL domain CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 Gene3D G3DSA:3.30.450.20 290 405 7.1E-18 T 29-03-2018 CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 Pfam PF10388 EAL-domain associated signalling protein domain 240 404 1.2E-79 T 29-03-2018 IPR018842 YkuI, C-terminal CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 SMART SM00052 3 241 1.4E-12 T 29-03-2018 IPR001633 EAL domain CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 Gene3D G3DSA:1.20.5.170 250 288 4.3E-18 T 29-03-2018 CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 SUPERFAMILY SSF103190 263 400 3.92E-43 T 29-03-2018 IPR029151 Periplasmic sensor domain-like CSW12_RS07785 3d3c588cacdf7218ca903401744af0c4 405 Gene3D G3DSA:3.20.20.450 3 249 3.0E-35 T 29-03-2018 IPR001633 EAL domain CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 238 361 5.1E-7 T 29-03-2018 CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 575 6.1E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 Pfam PF07694 5TMR of 5TMR-LYT 26 204 2.0E-49 T 29-03-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 Pfam PF06580 Histidine kinase 375 453 1.2E-24 T 29-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 Gene3D G3DSA:3.30.565.10 381 583 1.5E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 SMART SM00387 468 577 1.4E-7 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 SUPERFAMILY SSF55781 237 361 5.89E-9 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 SMART SM00065 235 370 1.8E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 Gene3D G3DSA:3.30.450.40 231 380 2.6E-8 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS26985 dd9c1389cb728463eb77cae484c4e6bc 589 SUPERFAMILY SSF55874 430 574 9.3E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 496 2.5E-135 T 29-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 Pfam PF00361 Proton-conducting membrane transporter 140 437 1.4E-66 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 8.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 8.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 8.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 8.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26230 6e4606a6d1f64468d7f1c23a5bdd386b 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 8.3E-34 T 29-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09925 13c542a46b15278119138ecd25254c73 338 Gene3D G3DSA:3.40.50.720 1 245 1.6E-65 T 29-03-2018 CSW12_RS09925 13c542a46b15278119138ecd25254c73 338 SUPERFAMILY SSF69572 3 328 1.31E-88 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS09925 13c542a46b15278119138ecd25254c73 338 Pfam PF00899 ThiF family 5 241 2.2E-63 T 29-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CSW12_RS02415 05f6ffbb21f0db16bf9992d224fe0c35 82 Gene3D G3DSA:1.10.3100.10 1 78 3.3E-11 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS02415 05f6ffbb21f0db16bf9992d224fe0c35 82 SUPERFAMILY SSF47413 4 66 1.49E-11 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS02415 05f6ffbb21f0db16bf9992d224fe0c35 82 SMART SM00530 8 63 0.0019 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS24605 8196e1bdf251da9b591b6b958e6ace2a 210 SUPERFAMILY SSF46785 7 188 1.17E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24605 8196e1bdf251da9b591b6b958e6ace2a 210 Gene3D G3DSA:1.10.10.10 1 79 4.2E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS24605 8196e1bdf251da9b591b6b958e6ace2a 210 Pfam PF01022 Bacterial regulatory protein, arsR family 10 52 2.3E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS17450 c1de3fc65ca00a47ab64c8ff385fbd7f 208 PIRSF PIRSF038959 1 203 2.7E-64 T 29-03-2018 IPR026272 Immunity protein SdpI CSW12_RS17450 c1de3fc65ca00a47ab64c8ff385fbd7f 208 Gene3D G3DSA:1.20.1250.20 4 207 1.5E-4 T 29-03-2018 CSW12_RS17450 c1de3fc65ca00a47ab64c8ff385fbd7f 208 Pfam PF07853 Protein of unknown function (DUF1648) 9 53 2.9E-9 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CSW12_RS06820 6a697856959ffaa41fea53364087ef78 365 Gene3D G3DSA:3.40.50.300 140 334 5.6E-4 T 29-03-2018 CSW12_RS14445 167e46fcb7792195d8c6ddf4d0ad2dad 293 Pfam PF00069 Protein kinase domain 76 244 1.4E-8 T 29-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CSW12_RS14445 167e46fcb7792195d8c6ddf4d0ad2dad 293 SUPERFAMILY SSF56112 71 286 2.82E-19 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS14445 167e46fcb7792195d8c6ddf4d0ad2dad 293 Gene3D G3DSA:1.10.510.10 74 292 6.7E-15 T 29-03-2018 CSW12_RS09665 93cdb92fa1af0dc1c6b0876ee090ae72 241 Gene3D G3DSA:3.20.20.370 20 241 3.3E-64 T 29-03-2018 CSW12_RS09665 93cdb92fa1af0dc1c6b0876ee090ae72 241 Pfam PF01522 Polysaccharide deacetylase 46 166 2.0E-34 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS09665 93cdb92fa1af0dc1c6b0876ee090ae72 241 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 46 237 1.8E-73 T 29-03-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB CSW12_RS09665 93cdb92fa1af0dc1c6b0876ee090ae72 241 SUPERFAMILY SSF88713 37 238 1.31E-66 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS26190 353840d50d803df214e73e41286d5016 234 Pfam PF12698 ABC-2 family transporter protein 48 222 6.3E-10 T 29-03-2018 CSW12_RS25065 f76dd0af25db8ecc29b51e66e486444b 192 Pfam PF03641 Possible lysine decarboxylase 46 175 5.0E-41 T 29-03-2018 IPR031100 LOG family CSW12_RS25065 f76dd0af25db8ecc29b51e66e486444b 192 Gene3D G3DSA:3.40.50.450 1 192 2.8E-57 T 29-03-2018 CSW12_RS25065 f76dd0af25db8ecc29b51e66e486444b 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 3 179 1.5E-62 T 29-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CSW12_RS25065 f76dd0af25db8ecc29b51e66e486444b 192 SUPERFAMILY SSF102405 1 179 1.98E-58 T 29-03-2018 CSW12_RS22975 0cfc8998bd3134f2edaebacfa95740f9 210 PIRSF PIRSF021278 2 210 8.0E-86 T 29-03-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 CSW12_RS22975 0cfc8998bd3134f2edaebacfa95740f9 210 Gene3D G3DSA:3.40.630.30 1 210 2.8E-51 T 29-03-2018 CSW12_RS22975 0cfc8998bd3134f2edaebacfa95740f9 210 Pfam PF00583 Acetyltransferase (GNAT) family 49 118 1.1E-4 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS22975 0cfc8998bd3134f2edaebacfa95740f9 210 SUPERFAMILY SSF55729 43 119 1.45E-7 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS24815 5fc233ccb88988b99dee0c10a12f9def 240 Gene3D G3DSA:3.60.15.10 2 229 7.8E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS24815 5fc233ccb88988b99dee0c10a12f9def 240 SUPERFAMILY SSF56281 6 227 3.54E-43 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS24815 5fc233ccb88988b99dee0c10a12f9def 240 Pfam PF00753 Metallo-beta-lactamase superfamily 18 212 1.1E-29 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS24815 5fc233ccb88988b99dee0c10a12f9def 240 SMART SM00849 20 212 1.8E-32 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 SUPERFAMILY SSF53328 2 206 9.03E-68 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 29-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 Gene3D G3DSA:3.10.25.10 207 314 5.9E-32 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 SUPERFAMILY SSF50486 205 310 3.77E-31 T 29-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 Pfam PF00551 Formyl transferase 3 180 2.4E-39 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 Gene3D G3DSA:3.40.50.170 1 206 7.7E-70 T 29-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 35.68 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 2.1E-27 T 29-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CSW12_RS08440 4054d860ec4040c824c2de9e5a905395 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 309 1.1E-112 T 29-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CSW12_RS23535 3844839a08fd7b1dd564ecdbaacea80f 127 Pfam PF03899 ATP synthase I chain 13 103 6.8E-14 T 29-03-2018 IPR005598 ATP synthase protein I CSW12_RS23535 3844839a08fd7b1dd564ecdbaacea80f 127 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 21 123 1.0E-54 T 29-03-2018 CSW12_RS15370 75efc6540c292799c3e35121b35e7cbd 215 Gene3D G3DSA:1.10.530.10 32 203 6.0E-14 T 29-03-2018 CSW12_RS15370 75efc6540c292799c3e35121b35e7cbd 215 SUPERFAMILY SSF53955 49 142 8.44E-8 T 29-03-2018 IPR023346 Lysozyme-like domain CSW12_RS15370 75efc6540c292799c3e35121b35e7cbd 215 Pfam PF13702 Lysozyme-like 45 199 9.8E-50 T 29-03-2018 CSW12_RS06405 0020a6b5eb01eea81ddc512fd6c59521 388 PIRSF PIRSF500216 1 388 2.0E-159 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB CSW12_RS06405 0020a6b5eb01eea81ddc512fd6c59521 388 PIRSF PIRSF016636 2 385 2.6E-79 T 29-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CSW12_RS06405 0020a6b5eb01eea81ddc512fd6c59521 388 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 121 345 1.9E-14 T 29-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CSW12_RS06405 0020a6b5eb01eea81ddc512fd6c59521 388 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 384 3.6E-155 T 29-03-2018 IPR024024 D-alanyl transfer protein DltB CSW12_RS24475 cfc9dcca9d068efc45243589ab452baf 187 SUPERFAMILY SSF55729 10 186 1.36E-38 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS24475 cfc9dcca9d068efc45243589ab452baf 187 Gene3D G3DSA:3.40.630.30 54 187 4.1E-19 T 29-03-2018 CSW12_RS24475 cfc9dcca9d068efc45243589ab452baf 187 Pfam PF13302 Acetyltransferase (GNAT) domain 16 160 5.4E-23 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS23305 12b305e927c7c4757ef244e0da7fe1af 161 SUPERFAMILY SSF55040 11 157 1.15E-57 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CSW12_RS23305 12b305e927c7c4757ef244e0da7fe1af 161 Gene3D G3DSA:3.30.70.640 2 160 8.2E-69 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CSW12_RS23305 12b305e927c7c4757ef244e0da7fe1af 161 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 160 35.764 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CSW12_RS23305 12b305e927c7c4757ef244e0da7fe1af 161 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 9.9E-65 T 29-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CSW12_RS23305 12b305e927c7c4757ef244e0da7fe1af 161 Pfam PF01967 MoaC family 15 152 5.5E-53 T 29-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CSW12_RS25395 2e0dd10256f3f6d0594d9c873b3c0004 772 Pfam PF07730 Histidine kinase 573 639 6.4E-7 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS25395 2e0dd10256f3f6d0594d9c873b3c0004 772 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 682 770 2.4E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS25395 2e0dd10256f3f6d0594d9c873b3c0004 772 SMART SM00387 678 771 5.0E-4 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS25395 2e0dd10256f3f6d0594d9c873b3c0004 772 SUPERFAMILY SSF55874 645 770 5.63E-17 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS25395 2e0dd10256f3f6d0594d9c873b3c0004 772 Gene3D G3DSA:3.30.565.10 528 771 1.2E-16 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS15170 e3d018e7d130dd4d66b22e2c74686376 296 Gene3D G3DSA:1.10.4100.10 97 273 2.1E-25 T 29-03-2018 CSW12_RS15170 e3d018e7d130dd4d66b22e2c74686376 296 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 290 4.1E-110 T 29-03-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS15170 e3d018e7d130dd4d66b22e2c74686376 296 Pfam PF03313 Serine dehydratase alpha chain 15 276 2.4E-71 T 29-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CSW12_RS09865 129a988124ded44dd6f6341acdfd7f9c 460 Pfam PF13520 Amino acid permease 22 443 4.6E-62 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS09865 129a988124ded44dd6f6341acdfd7f9c 460 PIRSF PIRSF006060 5 459 4.3E-96 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 1 459 6.0E-83 T 29-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 SUPERFAMILY SSF51905 425 458 5.67E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 SUPERFAMILY SSF51905 2 314 5.67E-41 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 Gene3D G3DSA:1.10.3110.10 120 199 3.0E-22 T 29-03-2018 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 SUPERFAMILY SSF54373 300 407 1.24E-20 T 29-03-2018 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 Pfam PF01593 Flavin containing amine oxidoreductase 31 458 3.7E-42 T 29-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 Gene3D G3DSA:3.90.660.20 45 119 1.2E-7 T 29-03-2018 CSW12_RS15955 637b8b6186587b42dad2140805ca55f3 463 Gene3D G3DSA:3.90.660.20 209 408 3.0E-33 T 29-03-2018 CSW12_RS17970 9641360ac1f484829ae6c4dee98a05ef 218 Gene3D G3DSA:1.20.120.570 10 206 4.3E-42 T 29-03-2018 CSW12_RS17970 9641360ac1f484829ae6c4dee98a05ef 218 Pfam PF10368 Putative cell-wall binding lipoprotein 12 212 3.1E-60 T 29-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CSW12_RS17970 9641360ac1f484829ae6c4dee98a05ef 218 SUPERFAMILY SSF140423 20 209 2.09E-57 T 29-03-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like CSW12_RS09720 af4e7990c4407380304ada284a75829f 96 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 81 7.3E-7 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS09720 af4e7990c4407380304ada284a75829f 96 Gene3D G3DSA:2.60.300.12 1 95 4.7E-12 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS09720 af4e7990c4407380304ada284a75829f 96 SUPERFAMILY SSF89360 1 79 2.35E-11 T 29-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CSW12_RS09720 af4e7990c4407380304ada284a75829f 96 PIRSF PIRSF034852 1 96 2.4E-40 T 29-03-2018 IPR008326 Uncharacterised conserved protein UCP034852 CSW12_RS07760 4420c5bae88c59b4e2f309c80d9ded92 512 Gene3D G3DSA:3.30.420.40 2 129 6.2E-29 T 29-03-2018 CSW12_RS07760 4420c5bae88c59b4e2f309c80d9ded92 512 Gene3D G3DSA:3.30.420.150 130 311 1.4E-38 T 29-03-2018 CSW12_RS07760 4420c5bae88c59b4e2f309c80d9ded92 512 Pfam PF02541 Ppx/GppA phosphatase family 22 307 1.6E-48 T 29-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CSW12_RS07760 4420c5bae88c59b4e2f309c80d9ded92 512 SUPERFAMILY SSF109604 316 508 6.59E-24 T 29-03-2018 CSW12_RS07760 4420c5bae88c59b4e2f309c80d9ded92 512 SUPERFAMILY SSF53067 9 129 3.89E-28 T 29-03-2018 CSW12_RS07760 4420c5bae88c59b4e2f309c80d9ded92 512 SUPERFAMILY SSF53067 132 307 2.39E-39 T 29-03-2018 CSW12_RS16025 30f3754013cb16697cf4b0452181cc40 156 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 137 9.3E-24 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CSW12_RS10765 ed24899bfb47d9ac5d9e6799c5451b06 85 Pfam PF13124 Protein of unknown function (DUF3963) 44 83 5.2E-30 T 29-03-2018 IPR025011 Protein of unknown function DUF3963 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 SUPERFAMILY SSF52943 2 285 1.57E-90 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 285 35.93 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 285 3.4E-108 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Gene3D G3DSA:3.40.1380.10 42 238 9.8E-75 T 29-03-2018 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Pfam PF00231 ATP synthase 3 285 1.8E-99 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 29-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 7.9E-40 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 7.9E-40 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 7.9E-40 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 7.9E-40 T 29-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Gene3D G3DSA:1.10.287.80 2 41 4.2E-17 T 29-03-2018 CSW12_RS26310 a8a49ebcae5cd6fc39db5e21f00b5dc6 286 Gene3D G3DSA:1.10.287.80 239 280 4.9E-14 T 29-03-2018 CSW12_RS26880 bb0ec3acbac5093452ec28c42f24ac2e 246 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 62 236 1.2E-55 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CSW12_RS26880 bb0ec3acbac5093452ec28c42f24ac2e 246 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 64 231 1.3E-61 T 29-03-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CSW12_RS26880 bb0ec3acbac5093452ec28c42f24ac2e 246 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 4 246 61.855 T 29-03-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 CSW12_RS18565 539231116207487bf1c8a1b9cc338ffd 253 SUPERFAMILY SSF53213 1 253 1.02E-80 T 29-03-2018 CSW12_RS18565 539231116207487bf1c8a1b9cc338ffd 253 PIRSF PIRSF006157 1 253 3.2E-95 T 29-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CSW12_RS18565 539231116207487bf1c8a1b9cc338ffd 253 Gene3D G3DSA:3.40.830.10 1 253 1.1E-79 T 29-03-2018 CSW12_RS18565 539231116207487bf1c8a1b9cc338ffd 253 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 244 1.2E-41 T 29-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CSW12_RS19195 29ae1a7c266576a638f51099227163c7 278 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 227 5.4E-8 T 29-03-2018 IPR021586 Transcription regulator TrmB, C-terminal CSW12_RS19195 29ae1a7c266576a638f51099227163c7 278 SUPERFAMILY SSF46785 2 97 3.19E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19195 29ae1a7c266576a638f51099227163c7 278 Gene3D G3DSA:1.10.10.10 1 101 1.2E-11 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19195 29ae1a7c266576a638f51099227163c7 278 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 5.5E-24 T 29-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CSW12_RS11390 3c147766bee64bfce64720e5b5ce4c83 279 Pfam PF14478 Domain of unknown function (DUF4430) 206 276 2.8E-15 T 29-03-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 CSW12_RS28720 e84f9e8720c4e6d5a5c35630a73b3293 152 Pfam PF10263 SprT-like family 7 97 1.5E-12 T 29-03-2018 IPR006640 SprT-like CSW12_RS28720 e84f9e8720c4e6d5a5c35630a73b3293 152 SMART SM00731 4 148 4.3E-49 T 29-03-2018 IPR006640 SprT-like CSW12_RS28720 e84f9e8720c4e6d5a5c35630a73b3293 152 Hamap MF_00745 Protein SprT-like. 4 148 40.613 T 29-03-2018 IPR023524 Uncharacterised protein family SprT-like CSW12_RS28720 e84f9e8720c4e6d5a5c35630a73b3293 152 Pfam PF17283 SprT-like zinc ribbon domain 114 147 9.7E-7 T 29-03-2018 IPR035240 SprT-like, zinc ribbon domain CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 SUPERFAMILY SSF47973 1 149 9.42E-61 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.574 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 29-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 PIRSF PIRSF002122 5 156 1.8E-59 T 29-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 Gene3D G3DSA:1.10.455.10 7 156 1.4E-59 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 6.4E-70 T 29-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CSW12_RS27960 0e338df27b45808f9deabb4d3aa57024 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 7.1E-66 T 29-03-2018 IPR023798 Ribosomal protein S7 domain CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 SUPERFAMILY SSF46689 357 406 2.91E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 SUPERFAMILY SSF46689 306 354 4.48E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 Gene3D G3DSA:1.10.10.60 360 408 9.1E-14 T 29-03-2018 CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 SMART SM00342 320 403 1.8E-31 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 Pfam PF12833 Helix-turn-helix domain 326 404 3.0E-21 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 Gene3D G3DSA:2.60.120.10 70 359 1.7E-15 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS15425 655cb0c5a6c62b7aca7bf98a2ef45d99 409 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 357 399 - T 29-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 2.4E-10 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 SUPERFAMILY SSF46689 9 76 9.98E-18 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.3E-5 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 Gene3D G3DSA:1.10.10.60 1 39 9.9E-14 T 29-03-2018 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 Pfam PF14278 Transcriptional regulator C-terminal region 95 173 1.2E-14 T 29-03-2018 CSW12_RS22465 56f90fb460b0e29563fb81eb8f0e978c 205 Gene3D G3DSA:1.10.260.40 40 76 2.4E-10 T 29-03-2018 CSW12_RS15310 dc964b7d470271b61084c96d172a1659 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS15310 dc964b7d470271b61084c96d172a1659 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS14550 dc964b7d470271b61084c96d172a1659 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS14550 dc964b7d470271b61084c96d172a1659 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS12885 dc964b7d470271b61084c96d172a1659 417 Pfam PF14319 Transposase zinc-binding domain 14 118 9.4E-29 T 29-03-2018 IPR026889 Transposase zinc-binding domain CSW12_RS12885 dc964b7d470271b61084c96d172a1659 417 Pfam PF04986 Putative transposase 142 312 1.7E-43 T 29-03-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 CSW12_RS11225 85ee390f6580a9132f4d86d43c3a2bbc 240 SUPERFAMILY SSF55729 31 236 3.31E-14 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS11225 85ee390f6580a9132f4d86d43c3a2bbc 240 Gene3D G3DSA:3.40.630.30 92 239 5.9E-15 T 29-03-2018 CSW12_RS07530 3217600de36bb959d595ecb12f63e56a 53 Pfam PF12841 YvrJ protein family 7 41 1.1E-17 T 29-03-2018 IPR024419 Protein of unknown function YvrJ CSW12_RS21440 4aa399d6441eeb36f0eb81aef966c982 125 Pfam PF01575 MaoC like domain 9 101 3.8E-6 T 29-03-2018 IPR002539 MaoC-like domain CSW12_RS21440 4aa399d6441eeb36f0eb81aef966c982 125 Gene3D G3DSA:3.10.129.10 1 123 7.7E-18 T 29-03-2018 CSW12_RS21440 4aa399d6441eeb36f0eb81aef966c982 125 SUPERFAMILY SSF54637 5 123 2.59E-21 T 29-03-2018 IPR029069 HotDog domain CSW12_RS14980 535b643a67eebfd88ce766d4c636e62b 246 Pfam PF12146 Serine aminopeptidase, S33 26 125 2.3E-12 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS14980 535b643a67eebfd88ce766d4c636e62b 246 SUPERFAMILY SSF53474 2 239 6.8E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS14980 535b643a67eebfd88ce766d4c636e62b 246 Gene3D G3DSA:3.40.50.1820 22 242 1.8E-20 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS26850 0821989ef9ddd3e4f0cdd3c944d7a2ac 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 4.4E-88 T 29-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS26850 0821989ef9ddd3e4f0cdd3c944d7a2ac 274 Gene3D G3DSA:3.40.1190.20 2 271 3.5E-59 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS26850 0821989ef9ddd3e4f0cdd3c944d7a2ac 274 SUPERFAMILY SSF53613 4 265 5.61E-79 T 29-03-2018 IPR029056 Ribokinase-like CSW12_RS26850 0821989ef9ddd3e4f0cdd3c944d7a2ac 274 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 1.7E-92 T 29-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 SMART SM00507 535 594 0.0011 T 29-03-2018 IPR003615 HNH nuclease CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 Gene3D G3DSA:3.30.70.270 117 363 2.2E-43 T 29-03-2018 CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 Pfam PF01348 Type II intron maturase 386 496 6.3E-15 T 29-03-2018 IPR024937 Domain X GO:0006397 CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 Gene3D G3DSA:3.40.1800.10 530 601 2.0E-5 T 29-03-2018 CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 88 362 7.7E-39 T 29-03-2018 IPR000477 Reverse transcriptase domain CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 SUPERFAMILY SSF56672 300 368 5.72E-47 T 29-03-2018 CSW12_RS30405 45cd79c7397ea564c912857d9814758f 602 SUPERFAMILY SSF56672 41 236 5.72E-47 T 29-03-2018 CSW12_RS15610 5b8ae350871894f324f98859e9cbfdfe 129 Pfam PF06486 Protein of unknown function (DUF1093) 27 115 1.0E-20 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS15610 5b8ae350871894f324f98859e9cbfdfe 129 SUPERFAMILY SSF159121 26 127 6.8E-32 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS15610 5b8ae350871894f324f98859e9cbfdfe 129 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 1 125 4.0E-9 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS13175 f99067cd9b068353eae267846c985f4b 273 Hamap MF_01273 Type II pantothenate kinase [coaW]. 3 270 46.963 T 29-03-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CSW12_RS13175 f99067cd9b068353eae267846c985f4b 273 SUPERFAMILY SSF53067 5 271 1.12E-55 T 29-03-2018 CSW12_RS13175 f99067cd9b068353eae267846c985f4b 273 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 4 269 2.9E-86 T 29-03-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 CSW12_RS13175 f99067cd9b068353eae267846c985f4b 273 PIRSF PIRSF036940 1 272 5.3E-134 T 29-03-2018 IPR011602 Type II pantothenate kinase, bacterial GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CSW12_RS13175 f99067cd9b068353eae267846c985f4b 273 Gene3D G3DSA:3.30.420.40 3 129 5.5E-8 T 29-03-2018 CSW12_RS13175 f99067cd9b068353eae267846c985f4b 273 Pfam PF03630 Fumble 5 269 1.5E-34 T 29-03-2018 IPR004567 Type II pantothenate kinase GO:0004594|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|Reactome: R-HSA-196783 CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 SMART SM00387 233 348 2.0E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 234 345 1.6E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 SUPERFAMILY SSF55874 179 344 2.51E-31 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 Gene3D G3DSA:3.30.565.10 148 345 2.0E-34 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 302 2.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 288 2.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 2.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS21825 004a7f47256f4eb8f6f44ec0a379addc 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 2.7E-11 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS30730 36f0531d9283ca8722732a18bf73354c 78 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 12 66 5.9E-7 T 29-03-2018 IPR018690 Protein of unknown function DUF2187 CSW12_RS15070 c3c0039d941e9d892b61dbf93df48441 280 SUPERFAMILY SSF56300 42 278 7.34E-35 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS15070 c3c0039d941e9d892b61dbf93df48441 280 Gene3D G3DSA:3.60.21.10 25 280 1.9E-24 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS15070 c3c0039d941e9d892b61dbf93df48441 280 Pfam PF00149 Calcineurin-like phosphoesterase 49 218 1.3E-15 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS26650 2194406cd0188e08cb28187505982b8a 241 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 233 1.1E-45 T 29-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CSW12_RS26650 2194406cd0188e08cb28187505982b8a 241 Gene3D G3DSA:3.20.20.190 1 241 3.4E-72 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS26650 2194406cd0188e08cb28187505982b8a 241 SUPERFAMILY SSF51695 3 240 1.44E-75 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS21450 eab66cb77379bc6c759e50c50046da3f 168 Pfam PF13302 Acetyltransferase (GNAT) domain 6 146 5.6E-29 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS21450 eab66cb77379bc6c759e50c50046da3f 168 SUPERFAMILY SSF55729 2 151 4.1E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS21450 eab66cb77379bc6c759e50c50046da3f 168 Gene3D G3DSA:3.40.630.30 1 167 2.7E-19 T 29-03-2018 CSW12_RS08800 b4dd2389dc8ef793647d0d9ecec5bd37 67 Pfam PF14035 YlzJ-like protein 3 65 9.0E-22 T 29-03-2018 IPR025619 YlzJ-like protein CSW12_RS11060 3f62818d1acd58bf959bed0e50a926ed 273 Gene3D G3DSA:2.160.20.80 38 260 2.7E-27 T 29-03-2018 CSW12_RS11060 3f62818d1acd58bf959bed0e50a926ed 273 SUPERFAMILY SSF141571 162 267 3.53E-25 T 29-03-2018 CSW12_RS11060 3f62818d1acd58bf959bed0e50a926ed 273 SUPERFAMILY SSF141571 53 88 3.53E-25 T 29-03-2018 CSW12_RS11060 3f62818d1acd58bf959bed0e50a926ed 273 Pfam PF00805 Pentapeptide repeats (8 copies) 202 241 2.6E-14 T 29-03-2018 IPR001646 Pentapeptide repeat CSW12_RS11600 87186935ce278add110b7672a507b39e 125 Gene3D G3DSA:3.10.129.10 1 125 3.5E-19 T 29-03-2018 CSW12_RS11600 87186935ce278add110b7672a507b39e 125 SUPERFAMILY SSF54637 3 122 1.06E-16 T 29-03-2018 IPR029069 HotDog domain CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR00701 60kDa inner membrane protein signature 124 147 2.9E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR00701 60kDa inner membrane protein signature 208 231 2.9E-15 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 Pfam PF02096 60Kd inner membrane protein 59 241 2.6E-61 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR01900 YidC translocation/secretion protein signature 197 221 6.4E-6 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 PRINTS PR01900 YidC translocation/secretion protein signature 175 190 6.4E-6 T 29-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 246 33.28 T 29-03-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes CSW12_RS27295 74d546a8d77cb3ff02c529e2d236a3ea 255 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 58 241 1.2E-67 T 29-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 105 2.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 2.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 2.6E-8 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 Pfam PF00561 alpha/beta hydrolase fold 65 176 9.4E-25 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 Pfam PF00561 alpha/beta hydrolase fold 190 273 1.9E-7 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 SUPERFAMILY SSF53474 43 287 2.13E-54 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS21375 616f592fcea444a1627ea07b06093109 294 Gene3D G3DSA:3.40.50.1820 35 294 5.1E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS15395 e3afcf6e4fc5f7c5472719e4ae4c36b4 499 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 17 470 2.5E-156 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS15395 e3afcf6e4fc5f7c5472719e4ae4c36b4 499 PIRSF PIRSF005690 5 485 2.0E-142 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS26400 d99e85d492f9d47b340d88e915cc2261 203 Pfam PF01613 Flavin reductase like domain 23 175 7.7E-23 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CSW12_RS26400 d99e85d492f9d47b340d88e915cc2261 203 Gene3D G3DSA:2.30.110.10 3 200 6.7E-48 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS26400 d99e85d492f9d47b340d88e915cc2261 203 SUPERFAMILY SSF50475 4 199 3.29E-44 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS26400 d99e85d492f9d47b340d88e915cc2261 203 SMART SM00903 20 176 3.7E-25 T 29-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CSW12_RS03315 c8c778f4be22721988e624b3ccb7c259 361 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 358 6.1E-141 T 29-03-2018 IPR008589 Protein of unknown function DUF871, prokaryotic CSW12_RS03315 c8c778f4be22721988e624b3ccb7c259 361 Gene3D G3DSA:2.40.100.10 245 360 6.9E-38 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS03315 c8c778f4be22721988e624b3ccb7c259 361 SUPERFAMILY SSF51445 2 243 1.1E-92 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS03315 c8c778f4be22721988e624b3ccb7c259 361 SUPERFAMILY SSF50891 246 360 4.93E-36 T 29-03-2018 IPR029000 Cyclophilin-like domain CSW12_RS03315 c8c778f4be22721988e624b3ccb7c259 361 Gene3D G3DSA:3.20.20.70 4 239 1.3E-96 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS18050 1eb9e6408438ae933ade537d142fb931 223 Pfam PF01596 O-methyltransferase 32 205 7.5E-42 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CSW12_RS18050 1eb9e6408438ae933ade537d142fb931 223 Gene3D G3DSA:3.40.50.150 1 223 1.4E-40 T 29-03-2018 CSW12_RS18050 1eb9e6408438ae933ade537d142fb931 223 SUPERFAMILY SSF53335 6 219 7.43E-41 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS13440 8f888f86fdec6200756f87dbb8c0d4f1 333 Gene3D G3DSA:2.30.30.40 49 139 8.6E-13 T 29-03-2018 CSW12_RS13440 8f888f86fdec6200756f87dbb8c0d4f1 333 Pfam PF00877 NlpC/P60 family 223 330 5.6E-26 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CSW12_RS13440 8f888f86fdec6200756f87dbb8c0d4f1 333 Gene3D G3DSA:2.30.260.10 256 330 7.3E-19 T 29-03-2018 CSW12_RS13440 8f888f86fdec6200756f87dbb8c0d4f1 333 SUPERFAMILY SSF54001 206 332 3.29E-40 T 29-03-2018 CSW12_RS13440 8f888f86fdec6200756f87dbb8c0d4f1 333 Gene3D G3DSA:3.90.1720.10 147 255 7.8E-16 T 29-03-2018 CSW12_RS14760 9bc314f062add3375e751848206e67bd 142 Pfam PF07486 Cell Wall Hydrolase 24 129 5.2E-15 T 29-03-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 CSW12_RS09575 b184fd7a3a61f930866b5a69f8a52612 82 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 77 1.1E-23 T 29-03-2018 IPR018680 Protein of unknown function DUF2164 CSW12_RS11685 cf0566d971969660a2a7fdca0026faf8 410 Gene3D G3DSA:3.60.21.10 19 332 4.7E-29 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS11685 cf0566d971969660a2a7fdca0026faf8 410 Pfam PF00149 Calcineurin-like phosphoesterase 35 250 3.9E-13 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS11685 cf0566d971969660a2a7fdca0026faf8 410 Pfam PF13285 Domain of unknown function (DUF4073) 251 407 3.0E-93 T 29-03-2018 IPR025142 Domain of unknown function DUF4073 CSW12_RS11685 cf0566d971969660a2a7fdca0026faf8 410 SUPERFAMILY SSF56300 34 321 5.11E-33 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 Gene3D G3DSA:1.25.40.10 2 144 6.8E-25 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 Gene3D G3DSA:1.25.40.10 145 365 7.1E-19 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 SMART SM00028 173 206 39.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 SMART SM00028 213 246 50.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 SMART SM00028 247 280 2.7 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 SMART SM00028 325 358 110.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 SMART SM00028 92 125 150.0 T 29-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CSW12_RS10390 3e3cb9744d9854cc7306424dc7e37cae 365 SUPERFAMILY SSF48452 92 308 1.48E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS30030 7fd6341a1c1a9934418cf45f3efcb7c2 397 Gene3D G3DSA:3.50.50.60 121 259 3.4E-40 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS30030 7fd6341a1c1a9934418cf45f3efcb7c2 397 Gene3D G3DSA:3.50.50.60 3 108 6.7E-11 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS30030 7fd6341a1c1a9934418cf45f3efcb7c2 397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 127 1.5E-10 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS30030 7fd6341a1c1a9934418cf45f3efcb7c2 397 SUPERFAMILY SSF51905 119 259 1.1E-23 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS30030 7fd6341a1c1a9934418cf45f3efcb7c2 397 SUPERFAMILY SSF51905 5 153 9.27E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS00200 5194659a8e3f25ef79a55e3137159ef0 268 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 161 237 1.7E-30 T 29-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CSW12_RS00200 5194659a8e3f25ef79a55e3137159ef0 268 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 164 236 3.6E-29 T 29-03-2018 IPR011741 Phage conserved hypothetical protein, C-terminal CSW12_RS22085 ad7026362d978c4fc1e4e1e893d22f5f 212 Gene3D G3DSA:1.10.10.60 15 43 8.3E-9 T 29-03-2018 CSW12_RS22085 ad7026362d978c4fc1e4e1e893d22f5f 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 56 1.7E-8 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS22085 ad7026362d978c4fc1e4e1e893d22f5f 212 Gene3D G3DSA:1.10.10.60 44 157 1.1E-8 T 29-03-2018 CSW12_RS22085 ad7026362d978c4fc1e4e1e893d22f5f 212 SUPERFAMILY SSF46689 12 66 2.89E-10 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS18545 c040a9059d4c46466f313d349346eec6 147 Gene3D G3DSA:3.40.630.30 1 139 1.3E-18 T 29-03-2018 CSW12_RS18545 c040a9059d4c46466f313d349346eec6 147 Pfam PF13673 Acetyltransferase (GNAT) domain 41 129 1.3E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS18545 c040a9059d4c46466f313d349346eec6 147 SUPERFAMILY SSF55729 1 141 3.81E-24 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS19690 571e3368898883df162b9ad7777d5166 412 SUPERFAMILY SSF52440 165 277 3.16E-6 T 29-03-2018 IPR016185 Pre-ATP-grasp domain CSW12_RS19690 571e3368898883df162b9ad7777d5166 412 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 19 405 3.2E-69 T 29-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain CSW12_RS19690 571e3368898883df162b9ad7777d5166 412 SUPERFAMILY SSF56059 3 160 2.83E-43 T 29-03-2018 CSW12_RS19690 571e3368898883df162b9ad7777d5166 412 SUPERFAMILY SSF56059 266 403 2.83E-43 T 29-03-2018 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 Gene3D G3DSA:1.20.1250.20 202 394 3.4E-28 T 29-03-2018 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 SUPERFAMILY SSF103473 3 387 8.37E-60 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 Pfam PF07690 Major Facilitator Superfamily 10 267 3.3E-27 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 Gene3D G3DSA:1.20.1250.20 2 193 1.7E-28 T 29-03-2018 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 131 152 3.1E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 92 110 3.1E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 44 62 3.1E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS23390 6d16d4cf3a7caceaaa80721dffd956c6 397 PRINTS PR01988 Putative bacilysin exporter bacE signature 279 302 3.1E-5 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS18075 792033456731de8bca35e4c8993667d2 254 Pfam PF00561 alpha/beta hydrolase fold 11 238 2.6E-14 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS18075 792033456731de8bca35e4c8993667d2 254 SUPERFAMILY SSF53474 7 250 4.82E-37 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS18075 792033456731de8bca35e4c8993667d2 254 Gene3D G3DSA:3.40.50.1820 4 254 2.3E-27 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS21485 98cffb421f0e657cd4f9ead72a8bab48 75 Pfam PF14143 YrhC-like protein 2 73 1.9E-27 T 29-03-2018 IPR025418 YrhC-like protein CSW12_RS19585 7844855f49070cc517da74d23851b867 161 PIRSF PIRSF031501 1 161 4.9E-55 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CSW12_RS19585 7844855f49070cc517da74d23851b867 161 Pfam PF06177 QueT transporter 7 153 3.8E-31 T 29-03-2018 IPR010387 Queuosine precursor transporter QueT GO:0005886 CSW12_RS17865 83ba9dab374d25cf48b78b98d1048b2f 626 PIRSF PIRSF018968 1 623 5.6E-137 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS17865 83ba9dab374d25cf48b78b98d1048b2f 626 Pfam PF02687 FtsX-like permease family 84 177 8.5E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 29-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 SUPERFAMILY SSF53178 1 185 6.54E-73 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 1 186 5.6E-73 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 Gene3D G3DSA:3.40.50.1470 1 186 2.3E-76 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 Pfam PF01195 Peptidyl-tRNA hydrolase 3 185 1.1E-61 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CSW12_RS27600 a8f8b656e69ef094e62b52eaae557321 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 38.653 T 29-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CSW12_RS08865 3187c39bcd6b5dfe32da153b57469711 303 Gene3D G3DSA:1.10.260.40 1 83 4.0E-11 T 29-03-2018 CSW12_RS08865 3187c39bcd6b5dfe32da153b57469711 303 SUPERFAMILY SSF47413 3 72 6.22E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS08865 3187c39bcd6b5dfe32da153b57469711 303 Pfam PF13413 Helix-turn-helix domain 8 68 1.2E-22 T 29-03-2018 CSW12_RS08865 3187c39bcd6b5dfe32da153b57469711 303 Pfam PF13464 Domain of unknown function (DUF4115) 217 279 6.5E-10 T 29-03-2018 IPR025194 Domain of unknown function DUF4115 CSW12_RS13350 2add05b4b9c10fce126ba88356fd5150 233 Gene3D G3DSA:3.40.50.1580 1 227 2.0E-52 T 29-03-2018 CSW12_RS13350 2add05b4b9c10fce126ba88356fd5150 233 Pfam PF01048 Phosphorylase superfamily 3 224 1.3E-49 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS13350 2add05b4b9c10fce126ba88356fd5150 233 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 3 227 1.3E-51 T 29-03-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CSW12_RS13350 2add05b4b9c10fce126ba88356fd5150 233 SUPERFAMILY SSF53167 3 229 6.28E-62 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS02540 05c7b66bf7a9c753e895bf0ede9b1160 140 Pfam PF05105 Bacteriophage holin family 18 127 1.6E-39 T 29-03-2018 IPR006480 Bacteriophage holin family CSW12_RS02540 05c7b66bf7a9c753e895bf0ede9b1160 140 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 13 137 1.7E-29 T 29-03-2018 IPR006480 Bacteriophage holin family CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 7.4E-159 T 29-03-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 1.2E-126 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 Gene3D G3DSA:1.10.580.10 11 260 2.4E-83 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 Gene3D G3DSA:1.10.580.10 292 351 7.0E-11 T 29-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 123 136 6.5E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 324 338 6.5E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 172 187 6.5E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 194 222 6.5E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 247 267 6.5E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PRINTS PR00143 Citrate synthase signature 304 320 6.5E-41 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 SUPERFAMILY SSF48256 2 371 2.22E-134 T 29-03-2018 IPR002020 Citrate synthase GO:0046912 CSW12_RS22595 56cc0531edd086ea7ae2c00c090635b6 371 PIRSF PIRSF001369 1 371 2.1E-150 T 29-03-2018 IPR024176 Citrate synthase, bacterial-type CSW12_RS12005 4302d20d84673818b23ba29918a0e076 194 SUPERFAMILY SSF46689 6 63 2.41E-13 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS12005 4302d20d84673818b23ba29918a0e076 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 7.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12005 4302d20d84673818b23ba29918a0e076 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 7.7E-7 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12005 4302d20d84673818b23ba29918a0e076 194 Gene3D G3DSA:1.10.357.10 60 194 2.4E-9 T 29-03-2018 CSW12_RS12005 4302d20d84673818b23ba29918a0e076 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 7.2E-11 T 29-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CSW12_RS12005 4302d20d84673818b23ba29918a0e076 194 Gene3D G3DSA:1.10.10.60 4 59 4.8E-15 T 29-03-2018 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 1.1E-31 T 29-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 SUPERFAMILY SSF54814 181 297 2.12E-43 T 29-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 1.4E-109 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 8.0E-26 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 Hamap MF_00367 GTPase Era [era]. 6 296 39.463 T 29-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 3.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 3.0E-5 T 29-03-2018 IPR006073 GTP binding domain GO:0005525 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 Gene3D G3DSA:3.40.50.300 10 185 2.4E-38 T 29-03-2018 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 Gene3D G3DSA:3.30.300.20 186 299 3.7E-46 T 29-03-2018 IPR015946 K homology domain-like, alpha/beta CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 Pfam PF07650 KH domain 208 285 1.5E-21 T 29-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CSW12_RS21110 218f4936ab5f4d07a108a61a8f1d0e93 301 SUPERFAMILY SSF52540 11 206 1.96E-53 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 424 46.997 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 422 7.3E-155 T 29-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 SUPERFAMILY SSF51556 54 367 8.6E-114 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 Gene3D G3DSA:2.30.40.10 1 67 1.8E-22 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 29-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 Pfam PF01979 Amidohydrolase family 51 419 5.0E-53 T 29-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 SUPERFAMILY SSF51338 1 53 4.96E-31 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 SUPERFAMILY SSF51338 366 424 4.96E-31 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS08315 282095e723e59a9558cee0d151a53ad5 428 Gene3D G3DSA:3.20.20.140 68 406 2.0E-110 T 29-03-2018 CSW12_RS30450 96e6108c19ccc321cc68d56892332a67 100 Gene3D G3DSA:1.20.5.50 46 79 0.1 T 29-03-2018 CSW12_RS30450 96e6108c19ccc321cc68d56892332a67 100 Gene3D G3DSA:1.20.5.50 1 44 0.027 T 29-03-2018 CSW12_RS09810 f3e18bb3555b38454b02e2f532b9d4f4 345 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 98 253 1.4E-32 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS09810 f3e18bb3555b38454b02e2f532b9d4f4 345 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 97 253 1.0E-38 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS20425 ce58049b75b9ec76580d529046aa32d7 48 Gene3D G3DSA:1.10.260.40 3 48 2.7E-4 T 29-03-2018 CSW12_RS20425 ce58049b75b9ec76580d529046aa32d7 48 Pfam PF14174 YycC-like protein 1 47 1.2E-28 T 29-03-2018 IPR025550 YycC-like protein CSW12_RS17890 36c4d2785ff84e8c4ce2a92feb6ff1b9 250 SUPERFAMILY SSF103032 14 250 5.75E-59 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 CSW12_RS17890 36c4d2785ff84e8c4ce2a92feb6ff1b9 250 Gene3D G3DSA:2.30.320.10 7 250 5.8E-46 T 29-03-2018 CSW12_RS17890 36c4d2785ff84e8c4ce2a92feb6ff1b9 250 Pfam PF09234 Domain of unknown function (DUF1963) 44 248 7.6E-38 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 CSW12_RS19645 14aeaf3f53773f7b8f2664e20b9957a6 484 Pfam PF01943 Polysaccharide biosynthesis protein 12 277 4.7E-21 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 21 372 1.5E-146 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 SUPERFAMILY SSF54593 12 359 3.74E-91 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 PIRSF PIRSF009283 7 372 4.0E-141 T 29-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 Gene3D G3DSA:3.10.180.10 11 174 6.8E-30 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 Gene3D G3DSA:3.10.180.10 175 372 2.8E-73 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 25 153 3.5E-6 T 29-03-2018 CSW12_RS28635 30979c8e6a65c31e3616eab728c60a3d 372 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 179 326 9.4E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 11 750 0.0 T 29-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 Gene3D G3DSA:3.40.50.300 290 393 4.5E-30 T 29-03-2018 CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 Pfam PF13361 UvrD-like helicase C-terminal domain 285 623 3.6E-75 T 29-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 Gene3D G3DSA:3.40.50.300 431 695 4.1E-51 T 29-03-2018 CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 Pfam PF00580 UvrD/REP helicase N-terminal domain 15 279 1.7E-87 T 29-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 SUPERFAMILY SSF52540 9 650 3.26E-188 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 Gene3D G3DSA:3.40.50.300 159 289 1.4E-34 T 29-03-2018 CSW12_RS00110 fb903652109d376c1aa40c683595065f 753 Gene3D G3DSA:3.40.50.300 5 158 2.2E-31 T 29-03-2018 CSW12_RS17755 edb2c6756a722ad2a6199abb2966e5b2 300 SUPERFAMILY SSF51430 8 295 3.93E-74 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17755 edb2c6756a722ad2a6199abb2966e5b2 300 Pfam PF00248 Aldo/keto reductase family 15 290 1.8E-60 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17755 edb2c6756a722ad2a6199abb2966e5b2 300 Gene3D G3DSA:3.20.20.100 1 300 1.1E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS17755 edb2c6756a722ad2a6199abb2966e5b2 300 PRINTS PR00069 Aldo-keto reductase signature 143 160 6.9E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS17755 edb2c6756a722ad2a6199abb2966e5b2 300 PRINTS PR00069 Aldo-keto reductase signature 112 130 6.9E-7 T 29-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CSW12_RS09390 d5f7a1cf5dce7c122ad62d437dc20ab9 137 PRINTS PR00502 NUDIX hydrolase family signature 46 61 1.2E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS09390 d5f7a1cf5dce7c122ad62d437dc20ab9 137 PRINTS PR00502 NUDIX hydrolase family signature 32 46 1.2E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS09390 d5f7a1cf5dce7c122ad62d437dc20ab9 137 Gene3D G3DSA:3.90.79.10 2 137 1.2E-22 T 29-03-2018 CSW12_RS09390 d5f7a1cf5dce7c122ad62d437dc20ab9 137 SUPERFAMILY SSF55811 5 132 3.11E-27 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS09390 d5f7a1cf5dce7c122ad62d437dc20ab9 137 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS09390 d5f7a1cf5dce7c122ad62d437dc20ab9 137 Pfam PF00293 NUDIX domain 8 116 1.3E-17 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS30415 57d3e5f0b524bf5924fb9096b3de9dbc 71 Pfam PF12750 Maff2 family 1 70 3.1E-37 T 29-03-2018 IPR024272 MAFF2-related CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 SUPERFAMILY SSF50249 31 92 3.03E-5 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 SMART SM00471 156 288 2.4E-6 T 29-03-2018 IPR003607 HD/PDEase domain CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 Gene3D G3DSA:1.10.3210.10 109 300 1.4E-13 T 29-03-2018 CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 Pfam PF01966 HD domain 161 278 1.8E-10 T 29-03-2018 IPR006674 HD domain CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 SUPERFAMILY SSF109604 137 280 2.07E-15 T 29-03-2018 CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 62.044 T 29-03-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 Gene3D G3DSA:2.40.50.140 2 108 1.0E-10 T 29-03-2018 CSW12_RS04395 b2815037da324fef6106f0a433f10d96 314 Pfam PF01336 OB-fold nucleic acid binding domain 28 89 2.4E-6 T 29-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CSW12_RS11195 7a041aa561abe753b86f4549b78551cd 397 Pfam PF07690 Major Facilitator Superfamily 231 387 1.8E-10 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS11195 7a041aa561abe753b86f4549b78551cd 397 SUPERFAMILY SSF103473 20 392 1.24E-34 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS11195 7a041aa561abe753b86f4549b78551cd 397 Gene3D G3DSA:1.20.1250.20 209 397 1.2E-20 T 29-03-2018 CSW12_RS11195 7a041aa561abe753b86f4549b78551cd 397 Gene3D G3DSA:1.20.1250.20 12 208 1.4E-13 T 29-03-2018 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 Gene3D G3DSA:3.40.50.150 74 265 1.1E-44 T 29-03-2018 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 SUPERFAMILY SSF47757 9 74 9.94E-10 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 SUPERFAMILY SSF53335 75 248 1.05E-44 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 SMART SM00138 9 263 1.8E-77 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 Pfam PF01739 CheR methyltransferase, SAM binding domain 75 250 7.4E-56 T 29-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 Gene3D G3DSA:1.10.155.10 6 73 4.7E-9 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 Pfam PF03705 CheR methyltransferase, all-alpha domain 12 62 1.7E-8 T 29-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 PRINTS PR00996 Glutamate methyltransferase family signature 68 80 2.7E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 2.7E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 2.7E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 2.7E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 PRINTS PR00996 Glutamate methyltransferase family signature 31 44 2.7E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS19405 cc7b01c13b9f8aa3ae79f599fbd01083 265 PRINTS PR00996 Glutamate methyltransferase family signature 138 154 2.7E-37 T 29-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CSW12_RS10880 64d94edd5cfc9adc92858bfc9da5cede 279 Gene3D G3DSA:3.90.1200.10 49 276 3.6E-11 T 29-03-2018 CSW12_RS10880 64d94edd5cfc9adc92858bfc9da5cede 279 SUPERFAMILY SSF56112 1 272 5.54E-24 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS10880 64d94edd5cfc9adc92858bfc9da5cede 279 Pfam PF01636 Phosphotransferase enzyme family 23 212 1.3E-7 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS06110 d5fddffdb3fa513223e4e084e3803848 150 TIGRFAM TIGR02719 repress_PhaQ: poly-beta-hydroxybutyrate-responsive repressor 4 141 1.8E-88 T 29-03-2018 IPR014091 Transcriptional repressor poly-beta-hydroxybutyrate-responsive CSW12_RS06110 d5fddffdb3fa513223e4e084e3803848 150 SUPERFAMILY SSF46785 15 121 6.49E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06110 d5fddffdb3fa513223e4e084e3803848 150 Pfam PF03551 Transcriptional regulator PadR-like family 32 103 3.5E-18 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS06110 d5fddffdb3fa513223e4e084e3803848 150 Gene3D G3DSA:1.10.10.10 15 115 1.2E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12030 657f2c9817cebdac0bb3a1e835daca85 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 71 96 6.1E-13 T 29-03-2018 CSW12_RS12030 657f2c9817cebdac0bb3a1e835daca85 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 235 261 6.1E-13 T 29-03-2018 CSW12_RS12030 657f2c9817cebdac0bb3a1e835daca85 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 213 234 6.1E-13 T 29-03-2018 CSW12_RS12030 657f2c9817cebdac0bb3a1e835daca85 510 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 301 313 6.1E-13 T 29-03-2018 CSW12_RS12030 657f2c9817cebdac0bb3a1e835daca85 510 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 69 109 7.7E-8 T 29-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS12030 657f2c9817cebdac0bb3a1e835daca85 510 Pfam PF00361 Proton-conducting membrane transporter 122 402 4.7E-60 T 29-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS16770 16c5e5c8527a801f63b5db14576e12fb 320 Gene3D G3DSA:3.40.50.1980 37 153 1.9E-28 T 29-03-2018 CSW12_RS16770 16c5e5c8527a801f63b5db14576e12fb 320 Pfam PF01497 Periplasmic binding protein 58 294 7.4E-31 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS16770 16c5e5c8527a801f63b5db14576e12fb 320 SUPERFAMILY SSF53807 41 314 2.7E-66 T 29-03-2018 CSW12_RS16770 16c5e5c8527a801f63b5db14576e12fb 320 Gene3D G3DSA:3.40.50.1980 154 320 2.4E-33 T 29-03-2018 CSW12_RS08795 b91d65a6fe61b94ceebc9360113518cd 249 SUPERFAMILY SSF52096 44 230 2.57E-36 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS08795 b91d65a6fe61b94ceebc9360113518cd 249 Pfam PF00574 Clp protease 46 222 5.2E-34 T 29-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CSW12_RS08795 b91d65a6fe61b94ceebc9360113518cd 249 Gene3D G3DSA:3.90.226.10 29 247 3.5E-25 T 29-03-2018 CSW12_RS24375 3700aeb41465ce41199a9718d699ebad 197 Pfam PF02632 BioY family 36 180 1.8E-29 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CSW12_RS24375 3700aeb41465ce41199a9718d699ebad 197 PIRSF PIRSF016661 1 190 3.7E-41 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Pfam PF00395 S-layer homology domain 37 79 4.7E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Pfam PF00395 S-layer homology domain 95 137 1.1E-9 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Pfam PF00395 S-layer homology domain 154 194 1.3E-13 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 SUPERFAMILY SSF69360 149 322 3.14E-26 T 29-03-2018 CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Gene3D G3DSA:2.20.120.10 247 281 8.3E-11 T 29-03-2018 CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Gene3D G3DSA:2.20.120.10 214 246 3.3E-7 T 29-03-2018 CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Gene3D G3DSA:2.10.270.10 282 375 6.4E-10 T 29-03-2018 CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Pfam PF14449 Pre-toxin TG 738 798 1.0E-5 T 29-03-2018 IPR027797 Pre-toxin TG domain CSW12_RS04015 bf1448210f97ea97a714eb9bef3cf9ad 922 Gene3D G3DSA:1.20.120.20 613 859 0.016 T 29-03-2018 CSW12_RS20695 31acca240a3ad12c76c27b9053543af5 221 Pfam PF13346 ABC-2 family transporter protein 3 217 1.4E-27 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CSW12_RS05490 f37a556c9a1d08c5c64c9f949599d81a 224 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 182 1.0E-69 T 29-03-2018 IPR022301 Integral membrane protein YjbE CSW12_RS05490 f37a556c9a1d08c5c64c9f949599d81a 224 Pfam PF03741 Integral membrane protein TerC family 11 181 8.9E-44 T 29-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CSW12_RS25025 cac39623e17e770325715122c73bc05f 198 Pfam PF09335 SNARE associated Golgi protein 31 156 8.6E-25 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS21570 a2aaa6728f2e0871e8cec4e722fd837b 88 Hamap MF_01507 UPF0297 protein . 1 85 28.156 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CSW12_RS21570 a2aaa6728f2e0871e8cec4e722fd837b 88 PIRSF PIRSF037258 1 88 6.4E-45 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CSW12_RS21570 a2aaa6728f2e0871e8cec4e722fd837b 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 2.1E-37 T 29-03-2018 IPR009309 Uncharacterised protein family UPF0297 CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 SUPERFAMILY SSF46955 3 114 1.68E-30 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 Pfam PF07739 TipAS antibiotic-recognition domain 130 238 1.3E-31 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 SMART SM00422 3 72 9.5E-27 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 Gene3D G3DSA:1.10.490.50 155 242 6.8E-28 T 29-03-2018 CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 SUPERFAMILY SSF89082 156 242 1.57E-29 T 29-03-2018 IPR012925 TipAS antibiotic-recognition domain CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 Pfam PF13411 MerR HTH family regulatory protein 3 69 1.1E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS24645 164b76408f5a05a2781a3a81c6bbc6c3 244 Gene3D G3DSA:1.10.1660.10 1 139 1.6E-41 T 29-03-2018 CSW12_RS10365 9456e34626a3c25c19f8b28cacb42db8 167 Gene3D G3DSA:3.40.630.30 2 161 1.1E-16 T 29-03-2018 CSW12_RS10365 9456e34626a3c25c19f8b28cacb42db8 167 SUPERFAMILY SSF55729 2 153 4.09E-33 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS10365 9456e34626a3c25c19f8b28cacb42db8 167 Pfam PF13302 Acetyltransferase (GNAT) domain 8 147 8.9E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS12815 0a53094e94c786a77fdc8ec0a9663744 338 Gene3D G3DSA:1.10.3470.10 39 320 5.0E-30 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS12815 0a53094e94c786a77fdc8ec0a9663744 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 313 5.4E-45 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS01670 a548c43539ef69f2cf219df4293061b2 160 Pfam PF07849 Protein of unknown function (DUF1641) 121 155 2.4E-11 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 Gene3D G3DSA:2.30.30.410 87 162 8.2E-12 T 29-03-2018 CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 SMART SM00287 89 149 9.9E-5 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 SMART SM00287 27 88 2.9E-11 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 Gene3D G3DSA:2.40.50.110 20 86 2.5E-17 T 29-03-2018 CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 SUPERFAMILY SSF50685 452 504 1.15E-10 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 Pfam PF06725 3D domain 454 514 3.1E-21 T 29-03-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 Gene3D G3DSA:2.40.40.10 276 513 1.5E-39 T 29-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CSW12_RS12860 e3c3246d7fa39541ae76fedc54731761 514 Pfam PF08239 Bacterial SH3 domain 36 84 1.2E-10 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS23735 f4d182fb9f755d1bc44c7159bb33d521 290 PIRSF PIRSF006483 1 289 2.7E-75 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS23735 f4d182fb9f755d1bc44c7159bb33d521 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 221 1.1E-48 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS23735 f4d182fb9f755d1bc44c7159bb33d521 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 227 281 2.7E-19 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS10570 186a463e40609bb46452100e083fd05a 338 Pfam PF01032 FecCD transport family 24 336 1.4E-89 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS10570 186a463e40609bb46452100e083fd05a 338 Gene3D G3DSA:1.10.3470.10 7 338 1.4E-64 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS10570 186a463e40609bb46452100e083fd05a 338 SUPERFAMILY SSF81345 9 336 2.35E-80 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS10040 41eed5d92950be6c5dd63949163a9dbc 113 PIRSF PIRSF016134 1 113 1.2E-43 T 29-03-2018 IPR016645 Uncharacterised conserved protein UCP016134 CSW12_RS10040 41eed5d92950be6c5dd63949163a9dbc 113 Pfam PF04266 ASCH domain 6 112 3.0E-16 T 29-03-2018 IPR007374 ASCH domain CSW12_RS10040 41eed5d92950be6c5dd63949163a9dbc 113 Gene3D G3DSA:2.30.130.30 1 112 3.0E-32 T 29-03-2018 CSW12_RS10040 41eed5d92950be6c5dd63949163a9dbc 113 SMART SM01022 5 113 1.6E-16 T 29-03-2018 IPR007374 ASCH domain CSW12_RS10040 41eed5d92950be6c5dd63949163a9dbc 113 SUPERFAMILY SSF88697 1 112 3.64E-35 T 29-03-2018 IPR015947 PUA-like domain CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 99 3.8E-18 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 SUPERFAMILY SSF51735 3 160 7.24E-34 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 PIRSF PIRSF000193 2 268 8.2E-83 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 Gene3D G3DSA:1.10.3730.10 160 271 2.3E-44 T 29-03-2018 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 266 3.1E-85 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 Gene3D G3DSA:3.40.50.720 1 159 2.4E-26 T 29-03-2018 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 266 26.862 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 SUPERFAMILY SSF48179 161 268 3.74E-39 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS15460 da4a84c143165ed5307c9ee025a155f2 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 4.7E-40 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CSW12_RS19950 7a5b84a7e08d59c164099a26465e49ac 293 PIRSF PIRSF006483 1 287 4.5E-91 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS19950 7a5b84a7e08d59c164099a26465e49ac 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 219 2.1E-63 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS19950 7a5b84a7e08d59c164099a26465e49ac 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 225 279 2.1E-22 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS31025 61bed12fde535e3c34c28f1c32e10e72 612 Pfam PF06114 IrrE N-terminal-like domain 181 256 2.8E-8 T 29-03-2018 IPR010359 IrrE N-terminal-like domain CSW12_RS18150 7b9d90acd192aa6bb7bd59c4f543a36b 338 PIRSF PIRSF000267 1 338 1.2E-112 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS18150 7b9d90acd192aa6bb7bd59c4f543a36b 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 1.8E-104 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS18150 7b9d90acd192aa6bb7bd59c4f543a36b 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 226 2.5E-85 T 29-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CSW12_RS28140 9afb5d25518cc761f7ad38b0d8249bb9 264 Pfam PF02361 Cobalt transport protein 13 235 6.1E-58 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CSW12_RS28140 9afb5d25518cc761f7ad38b0d8249bb9 264 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 36.66 T 29-03-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 CSW12_RS25855 1f586535fd2aa5190e792e4ddfbfdbbb 586 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 128 555 56.802 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CSW12_RS25855 1f586535fd2aa5190e792e4ddfbfdbbb 586 Pfam PF01964 Radical SAM ThiC family 129 549 7.4E-205 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CSW12_RS25855 1f586535fd2aa5190e792e4ddfbfdbbb 586 Pfam PF13667 ThiC-associated domain 16 88 1.6E-27 T 29-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CSW12_RS25855 1f586535fd2aa5190e792e4ddfbfdbbb 586 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 128 552 2.7E-222 T 29-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CSW12_RS17330 4ef9a2e737665ff60d50899886a4cac5 226 Pfam PF12207 Domain of unknown function (DUF3600) 65 224 1.9E-77 T 29-03-2018 IPR022019 Domain of unknown function DUF3600 CSW12_RS17330 4ef9a2e737665ff60d50899886a4cac5 226 Gene3D G3DSA:1.10.3950.10 69 202 7.9E-51 T 29-03-2018 CSW12_RS10675 ae9ca020debb8f5544b9d73916172371 230 Pfam PF00027 Cyclic nucleotide-binding domain 35 117 8.3E-13 T 29-03-2018 IPR000595 Cyclic nucleotide-binding domain CSW12_RS10675 ae9ca020debb8f5544b9d73916172371 230 SUPERFAMILY SSF51206 21 140 1.57E-26 T 29-03-2018 IPR018490 Cyclic nucleotide-binding-like CSW12_RS10675 ae9ca020debb8f5544b9d73916172371 230 Gene3D G3DSA:1.10.10.10 148 230 3.1E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10675 ae9ca020debb8f5544b9d73916172371 230 Gene3D G3DSA:2.60.120.10 2 147 5.9E-19 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS10675 ae9ca020debb8f5544b9d73916172371 230 SUPERFAMILY SSF46785 151 226 1.25E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10675 ae9ca020debb8f5544b9d73916172371 230 Pfam PF13545 Crp-like helix-turn-helix domain 154 224 2.3E-7 T 29-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 Gene3D G3DSA:1.10.287.950 320 564 4.6E-52 T 29-03-2018 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 Gene3D G3DSA:1.10.287.950 142 319 4.7E-6 T 29-03-2018 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 514 6.4E-46 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 SUPERFAMILY SSF58104 292 561 1.7E-75 T 29-03-2018 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 SUPERFAMILY SSF58104 225 259 1.7E-75 T 29-03-2018 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 SMART SM00283 286 561 9.1E-79 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 SMART SM00304 203 257 3.8E-14 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS24990 9de80baf1fb24d7a34d25ed95ff1dd65 564 Pfam PF00672 HAMP domain 205 254 1.1E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS26100 1d5717eeacb42c187538772f90c2398e 319 Gene3D G3DSA:3.90.550.10 1 313 4.0E-56 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS26100 1d5717eeacb42c187538772f90c2398e 319 SUPERFAMILY SSF53448 2 225 1.08E-57 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS26100 1d5717eeacb42c187538772f90c2398e 319 Pfam PF00535 Glycosyl transferase family 2 4 161 2.7E-34 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS29965 dbc6aadeb5c507533b88ddc932de9cd0 127 Gene3D G3DSA:1.20.5.40 41 68 4.9E-12 T 29-03-2018 CSW12_RS29965 dbc6aadeb5c507533b88ddc932de9cd0 127 Gene3D G3DSA:3.40.50.1390 3 40 2.1E-8 T 29-03-2018 CSW12_RS29965 dbc6aadeb5c507533b88ddc932de9cd0 127 Pfam PF00239 Resolvase, N terminal domain 6 70 4.4E-14 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS29965 dbc6aadeb5c507533b88ddc932de9cd0 127 SUPERFAMILY SSF53041 6 70 3.66E-14 T 29-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CSW12_RS03655 0b40cdafe68ea2173a5fd5b41b59a4d0 118 SUPERFAMILY SSF158622 4 113 4.19E-35 T 29-03-2018 IPR023378 YheA/YmcA-like domain CSW12_RS03655 0b40cdafe68ea2173a5fd5b41b59a4d0 118 Hamap MF_01526 UPF0342 protein . 2 113 19.038 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CSW12_RS03655 0b40cdafe68ea2173a5fd5b41b59a4d0 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 1.7E-23 T 29-03-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA CSW12_RS03655 0b40cdafe68ea2173a5fd5b41b59a4d0 118 Gene3D G3DSA:1.20.1500.10 4 109 9.7E-27 T 29-03-2018 IPR023378 YheA/YmcA-like domain CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 SUPERFAMILY SSF48179 175 283 7.25E-32 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 SUPERFAMILY SSF55021 289 347 2.14E-7 T 29-03-2018 CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 SUPERFAMILY SSF51735 4 170 4.27E-45 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 Pfam PF02153 Prephenate dehydrogenase 17 273 1.9E-77 T 29-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 Gene3D G3DSA:3.40.50.720 1 173 1.4E-24 T 29-03-2018 CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 Gene3D G3DSA:3.30.70.260 294 359 2.6E-6 T 29-03-2018 CSW12_RS12920 4fa41b4bd0649696f6c63f928d104c92 366 Gene3D G3DSA:1.10.3660.10 183 287 1.0E-24 T 29-03-2018 CSW12_RS15150 62947ef325f16677b2279a5d8eb29dea 87 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 10 74 2.0E-23 T 29-03-2018 CSW12_RS15150 62947ef325f16677b2279a5d8eb29dea 87 Pfam PF11132 Transcriptional regulator protein (SplA) 7 78 5.7E-30 T 29-03-2018 IPR022608 Transcription regulator SplA CSW12_RS18205 27427353c8ac9da85c33f7e187e3ad7d 257 Gene3D G3DSA:3.40.50.300 1 250 9.5E-57 T 29-03-2018 CSW12_RS18205 27427353c8ac9da85c33f7e187e3ad7d 257 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS18205 27427353c8ac9da85c33f7e187e3ad7d 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 6.4E-9 T 29-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CSW12_RS18205 27427353c8ac9da85c33f7e187e3ad7d 257 SUPERFAMILY SSF52540 3 246 2.11E-59 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18205 27427353c8ac9da85c33f7e187e3ad7d 257 Pfam PF00005 ABC transporter 21 176 5.5E-31 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS18205 27427353c8ac9da85c33f7e187e3ad7d 257 SMART SM00382 29 225 2.5E-11 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 Pfam PF00258 Flavodoxin 6 133 4.0E-28 T 29-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 SUPERFAMILY SSF52218 3 146 9.51E-40 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 PRINTS PR00369 Flavodoxin signature 5 18 4.6E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 PRINTS PR00369 Flavodoxin signature 82 92 4.6E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 PRINTS PR00369 Flavodoxin signature 53 64 4.6E-5 T 29-03-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 TIGRFAM TIGR01753 flav_short: flavodoxin 4 143 1.1E-46 T 29-03-2018 IPR010087 Flavodoxin, short chain GO:0010181 CSW12_RS10055 f1cc64aef01563fae4821ac12103d7a3 147 Gene3D G3DSA:3.40.50.360 1 147 2.4E-36 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS29995 b209c1bf90c603126f9c6c0d1cbb24b5 62 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 56 1.4E-14 T 29-03-2018 IPR018690 Protein of unknown function DUF2187 CSW12_RS07170 794a4eb030f31fa97e0e88153c0413b2 79 Pfam PF13025 Protein of unknown function (DUF3886) 11 77 6.5E-22 T 29-03-2018 IPR024980 Protein of unknown function DUF3886 CSW12_RS18730 1b9ab8582a244df2e82a120c0b00f275 267 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 17 236 1.2E-86 T 29-03-2018 IPR022488 Polyphosphate kinase-2-related CSW12_RS18730 1b9ab8582a244df2e82a120c0b00f275 267 PIRSF PIRSF028756 2 264 9.8E-78 T 29-03-2018 IPR016898 Polyphosphate kinase 2 CSW12_RS18730 1b9ab8582a244df2e82a120c0b00f275 267 SUPERFAMILY SSF52540 48 241 2.93E-29 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS18730 1b9ab8582a244df2e82a120c0b00f275 267 Gene3D G3DSA:3.40.50.300 1 245 5.7E-88 T 29-03-2018 CSW12_RS11070 11c77b4fb7faf22814d97dee273819d3 270 Pfam PF13704 Glycosyl transferase family 2 27 113 2.7E-11 T 29-03-2018 CSW12_RS14205 bf2433c77abf43eda633fec9983a9d15 125 Gene3D G3DSA:2.30.29.50 13 102 5.2E-39 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CSW12_RS14205 bf2433c77abf43eda633fec9983a9d15 125 SUPERFAMILY SSF50729 6 124 1.68E-44 T 29-03-2018 IPR011993 PH domain-like CSW12_RS14205 bf2433c77abf43eda633fec9983a9d15 125 Pfam PF08000 Bacterial PH domain 3 121 6.1E-49 T 29-03-2018 IPR012544 Bacterial Pleckstrin homology domain CSW12_RS26945 b0dfcc5c16b574fad18dac87a1131b81 323 Gene3D G3DSA:3.90.550.10 1 205 2.8E-33 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS26945 b0dfcc5c16b574fad18dac87a1131b81 323 Pfam PF00535 Glycosyl transferase family 2 6 166 1.6E-33 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS26945 b0dfcc5c16b574fad18dac87a1131b81 323 SUPERFAMILY SSF53448 2 223 2.81E-37 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS13035 15e78d8f4b69521996253b9af35e7357 133 Pfam PF13673 Acetyltransferase (GNAT) domain 42 124 3.5E-11 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13035 15e78d8f4b69521996253b9af35e7357 133 SUPERFAMILY SSF55729 49 124 4.63E-13 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13035 15e78d8f4b69521996253b9af35e7357 133 Gene3D G3DSA:3.40.630.30 10 133 1.5E-10 T 29-03-2018 CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 Gene3D G3DSA:3.40.50.720 1 116 5.1E-21 T 29-03-2018 CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 SUPERFAMILY SSF75615 106 194 2.09E-20 T 29-03-2018 CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 Gene3D G3DSA:3.30.160.110 117 142 2.7E-12 T 29-03-2018 CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 SUPERFAMILY SSF51735 1 107 8.59E-19 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 186 6.2E-39 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 Pfam PF13241 Putative NAD(P)-binding 4 112 1.4E-26 T 29-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS06720 4c3a43500e56750b5c8728bef46f4b38 204 Pfam PF14824 Sirohaem biosynthesis protein central 116 142 6.9E-11 T 29-03-2018 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CSW12_RS12895 482c9773ed3f299224902fd9a48cc121 1170 Gene3D G3DSA:3.40.50.1220 18 180 1.3E-6 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS12895 482c9773ed3f299224902fd9a48cc121 1170 Pfam PF13289 SIR2-like domain 120 246 3.5E-16 T 29-03-2018 CSW12_RS12895 482c9773ed3f299224902fd9a48cc121 1170 SUPERFAMILY SSF52467 22 216 5.61E-14 T 29-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CSW12_RS12895 482c9773ed3f299224902fd9a48cc121 1170 Pfam PF13212 Domain of unknown function (DUF4020) 981 1156 8.7E-73 T 29-03-2018 IPR025093 Domain of unknown function DUF4020 CSW12_RS13845 2ced1ea61f08ba86768cbbfb4a4b48f9 198 Pfam PF00583 Acetyltransferase (GNAT) family 63 153 2.8E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13845 2ced1ea61f08ba86768cbbfb4a4b48f9 198 SUPERFAMILY SSF55729 14 182 8.51E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13845 2ced1ea61f08ba86768cbbfb4a4b48f9 198 Gene3D G3DSA:3.40.630.30 8 188 7.2E-27 T 29-03-2018 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 Gene3D G3DSA:1.20.1250.20 1 198 3.7E-22 T 29-03-2018 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 164 181 3.3E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 13 35 3.3E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 76 94 3.3E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 299 322 3.3E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 PRINTS PR01988 Putative bacilysin exporter bacE signature 361 384 3.3E-6 T 29-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 SUPERFAMILY SSF103473 1 395 3.92E-43 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 Gene3D G3DSA:1.20.1250.20 206 408 4.5E-17 T 29-03-2018 CSW12_RS14420 20404294a68a0316f21d3f9d5948a88a 410 Pfam PF07690 Major Facilitator Superfamily 16 359 7.6E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS19135 868598745835cb3ba3446db3816c650a 330 Gene3D G3DSA:3.40.50.300 1 267 7.0E-68 T 29-03-2018 CSW12_RS19135 868598745835cb3ba3446db3816c650a 330 SUPERFAMILY SSF50331 250 318 6.8E-7 T 29-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CSW12_RS19135 868598745835cb3ba3446db3816c650a 330 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS19135 868598745835cb3ba3446db3816c650a 330 SMART SM00382 27 215 1.1E-16 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS19135 868598745835cb3ba3446db3816c650a 330 SUPERFAMILY SSF52540 3 244 3.49E-82 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19135 868598745835cb3ba3446db3816c650a 330 Pfam PF00005 ABC transporter 18 165 2.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS21790 6964f428768359fb37e0187ccaed0084 380 PIRSF PIRSF005572 1 376 1.0E-116 T 29-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CSW12_RS21790 6964f428768359fb37e0187ccaed0084 380 SUPERFAMILY SSF53383 2 370 2.6E-91 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS21790 6964f428768359fb37e0187ccaed0084 380 Pfam PF00266 Aminotransferase class-V 3 361 3.5E-72 T 29-03-2018 IPR000192 Aminotransferase class V domain CSW12_RS21790 6964f428768359fb37e0187ccaed0084 380 Gene3D G3DSA:3.40.640.10 11 253 3.5E-49 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS21790 6964f428768359fb37e0187ccaed0084 380 Gene3D G3DSA:3.90.1150.10 260 376 3.9E-29 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS00630 583bde40a1bee0a2a987877ba5c3f46a 421 Gene3D G3DSA:3.30.360.30 182 416 5.8E-44 T 29-03-2018 IPR023181 Homospermidine synthase-like, domain KEGG: 00960+2.5.1.44 CSW12_RS00630 583bde40a1bee0a2a987877ba5c3f46a 421 Gene3D G3DSA:3.40.50.720 5 181 1.4E-10 T 29-03-2018 CSW12_RS25685 1fea34309aa1e59eb168b1a45135ecf7 234 Gene3D G3DSA:3.40.50.2020 27 234 5.3E-23 T 29-03-2018 CSW12_RS25685 1fea34309aa1e59eb168b1a45135ecf7 234 Pfam PF00156 Phosphoribosyl transferase domain 142 232 2.5E-9 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS25685 1fea34309aa1e59eb168b1a45135ecf7 234 SUPERFAMILY SSF53271 71 232 2.27E-25 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS20110 f4a86fa6ac725ce795c37c4dca5e1ccd 153 Gene3D G3DSA:3.40.50.960 2 66 6.2E-24 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20110 f4a86fa6ac725ce795c37c4dca5e1ccd 153 Gene3D G3DSA:3.40.50.960 67 153 1.1E-41 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20110 f4a86fa6ac725ce795c37c4dca5e1ccd 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 11 149 4.9E-60 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20110 f4a86fa6ac725ce795c37c4dca5e1ccd 153 SUPERFAMILY SSF52121 2 152 1.18E-63 T 29-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20110 f4a86fa6ac725ce795c37c4dca5e1ccd 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 12 147 4.0E-60 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS20110 f4a86fa6ac725ce795c37c4dca5e1ccd 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 7 152 31.399 T 29-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 SMART SM00382 275 468 2.6E-5 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 SMART SM00382 31 219 1.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 Gene3D G3DSA:3.40.50.300 252 487 7.4E-44 T 29-03-2018 CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 Gene3D G3DSA:3.40.50.300 1 226 6.6E-53 T 29-03-2018 CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 Pfam PF00005 ABC transporter 267 419 1.1E-23 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 Pfam PF00005 ABC transporter 22 165 2.8E-30 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 SUPERFAMILY SSF52540 264 478 1.31E-47 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS12805 56d9eacd76a917d7203ffade3a6672ec 493 SUPERFAMILY SSF52540 5 223 2.49E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 SUPERFAMILY SSF64518 1 278 6.8E-81 T 29-03-2018 CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 Pfam PF00700 Bacterial flagellin C-terminal helical region 193 277 4.9E-24 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 137 2.2E-35 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 Gene3D G3DSA:1.20.1330.10 38 250 1.4E-56 T 29-03-2018 CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 PRINTS PR00207 Flagellin signature 74 93 1.4E-18 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 PRINTS PR00207 Flagellin signature 35 52 1.4E-18 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19275 23368caf271ad91fae51c151a9d278bd 278 PRINTS PR00207 Flagellin signature 109 132 1.4E-18 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19260 2527e72287c1ece1d4a88aba8b3e392c 74 Gene3D G3DSA:2.30.330.10 1 74 2.3E-11 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19260 2527e72287c1ece1d4a88aba8b3e392c 74 SUPERFAMILY SSF101801 3 72 1.31E-13 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS19260 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 49 64 1.7E-5 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19260 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 3 19 1.7E-5 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19260 2527e72287c1ece1d4a88aba8b3e392c 74 PRINTS PR00956 Flagellar motor switch protein FliN signature 20 36 1.7E-5 T 29-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CSW12_RS19260 2527e72287c1ece1d4a88aba8b3e392c 74 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 5 72 3.3E-10 T 29-03-2018 IPR001543 Surface presentation of antigen (SpoA) CSW12_RS13420 2b93a811a65c4b2784d2f51e448654d7 308 Gene3D G3DSA:3.20.20.100 1 308 3.0E-80 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS13420 2b93a811a65c4b2784d2f51e448654d7 308 Pfam PF00248 Aldo/keto reductase family 15 308 7.6E-67 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS13420 2b93a811a65c4b2784d2f51e448654d7 308 SUPERFAMILY SSF51430 1 308 1.44E-81 T 29-03-2018 IPR023210 NADP-dependent oxidoreductase domain CSW12_RS25755 5029dd3936dfb1b2ff8ef3e7cf718d9f 393 TIGRFAM TIGR00937 2A51: chromate efflux transporter 19 387 3.2E-141 T 29-03-2018 IPR014047 Chromate transporter, long chain CSW12_RS25755 5029dd3936dfb1b2ff8ef3e7cf718d9f 393 Pfam PF02417 Chromate transporter 225 386 6.7E-41 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CSW12_RS25755 5029dd3936dfb1b2ff8ef3e7cf718d9f 393 Pfam PF02417 Chromate transporter 12 177 1.8E-35 T 29-03-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 CSW12_RS25755 5029dd3936dfb1b2ff8ef3e7cf718d9f 393 PIRSF PIRSF004810 2 393 3.5E-128 T 29-03-2018 IPR014047 Chromate transporter, long chain CSW12_RS06890 f772e6c727808a211175002c3667d7f4 64 Pfam PF13062 Protein of unknown function (DUF3924) 1 62 4.2E-46 T 29-03-2018 IPR025038 Protein of unknown function DUF3924 CSW12_RS30025 6dda89ac5945359d6736276cf82bd5c3 360 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 59 342 5.5E-7 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS30025 6dda89ac5945359d6736276cf82bd5c3 360 SUPERFAMILY SSF56219 37 352 6.15E-31 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS30025 6dda89ac5945359d6736276cf82bd5c3 360 Gene3D G3DSA:3.60.10.10 42 351 9.2E-28 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS13615 5d95e9d246c1c785e6c17f2e3939e534 126 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 121 1.6E-25 T 29-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CSW12_RS13615 5d95e9d246c1c785e6c17f2e3939e534 126 Gene3D G3DSA:3.10.490.10 1 126 1.2E-29 T 29-03-2018 CSW12_RS13615 5d95e9d246c1c785e6c17f2e3939e534 126 SUPERFAMILY SSF110857 1 124 3.92E-32 T 29-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CSW12_RS20700 e33402414e4b62d59380a4a6f2550db1 290 SMART SM00382 25 204 6.6E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS20700 e33402414e4b62d59380a4a6f2550db1 290 Gene3D G3DSA:3.40.50.300 1 238 2.7E-51 T 29-03-2018 CSW12_RS20700 e33402414e4b62d59380a4a6f2550db1 290 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS20700 e33402414e4b62d59380a4a6f2550db1 290 Pfam PF00005 ABC transporter 16 155 8.7E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS20700 e33402414e4b62d59380a4a6f2550db1 290 SUPERFAMILY SSF52540 2 218 9.5E-51 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS13795 3cf2a655f6435914a00dbfec42ce27c6 332 Gene3D G3DSA:3.40.50.970 3 332 3.0E-90 T 29-03-2018 CSW12_RS13795 3cf2a655f6435914a00dbfec42ce27c6 332 SUPERFAMILY SSF52518 10 330 1.97E-105 T 29-03-2018 IPR029061 Thiamin diphosphate-binding fold CSW12_RS13795 3cf2a655f6435914a00dbfec42ce27c6 332 Pfam PF00676 Dehydrogenase E1 component 23 318 6.1E-95 T 29-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CSW12_RS28345 73c9d2afda034694a59c44f3de24f230 471 Gene3D G3DSA:3.30.465.10 81 204 1.4E-29 T 29-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CSW12_RS28345 73c9d2afda034694a59c44f3de24f230 471 SUPERFAMILY SSF55103 274 456 1.63E-20 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CSW12_RS28345 73c9d2afda034694a59c44f3de24f230 471 SUPERFAMILY SSF55103 180 218 1.63E-20 T 29-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CSW12_RS28345 73c9d2afda034694a59c44f3de24f230 471 SUPERFAMILY SSF56176 23 202 2.43E-38 T 29-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CSW12_RS28345 73c9d2afda034694a59c44f3de24f230 471 Pfam PF04030 D-arabinono-1,4-lactone oxidase 197 467 2.0E-6 T 29-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CSW12_RS28345 73c9d2afda034694a59c44f3de24f230 471 Pfam PF01565 FAD binding domain 42 173 2.1E-27 T 29-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 Pfam PF01047 MarR family 37 94 5.0E-16 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 Gene3D G3DSA:1.10.10.10 3 142 5.1E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 SUPERFAMILY SSF46785 6 141 1.19E-30 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 3.7E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 3.7E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 3.7E-7 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS12110 a695b8c808c53ee191d0bb1420d218e7 147 SMART SM00347 30 130 2.8E-23 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS05240 4f010daad7856fdcc3aa18ce56e31512 365 Pfam PF01757 Acyltransferase family 10 321 7.2E-14 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS01820 73d33c05e738641378a1f2b80229cccd 140 PRINTS PR00502 NUDIX hydrolase family signature 30 44 3.4E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS01820 73d33c05e738641378a1f2b80229cccd 140 PRINTS PR00502 NUDIX hydrolase family signature 44 59 3.4E-9 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS01820 73d33c05e738641378a1f2b80229cccd 140 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS01820 73d33c05e738641378a1f2b80229cccd 140 Gene3D G3DSA:3.90.79.10 1 124 4.4E-24 T 29-03-2018 CSW12_RS01820 73d33c05e738641378a1f2b80229cccd 140 SUPERFAMILY SSF55811 2 109 2.3E-26 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS01820 73d33c05e738641378a1f2b80229cccd 140 Pfam PF00293 NUDIX domain 5 112 1.3E-19 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS30815 99c1ed28261e81769968204ebd610188 329 Gene3D G3DSA:3.40.50.1820 41 324 6.9E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS30815 99c1ed28261e81769968204ebd610188 329 Pfam PF09752 Abhydrolase domain containing 18 119 209 4.0E-5 T 29-03-2018 IPR019149 Abhydrolase domain containing 18 CSW12_RS30815 99c1ed28261e81769968204ebd610188 329 SUPERFAMILY SSF53474 83 328 3.13E-25 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS24805 cd69495a42da3c3014bbefd83735d0ad 237 Pfam PF02517 CAAX protease self-immunity 143 228 6.1E-19 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS29200 0775ab902de6982949a0e41d811fb985 182 Pfam PF12648 TcpE family 25 115 1.3E-10 T 29-03-2018 IPR025608 TcpE family CSW12_RS10475 f5a9149ec72723f3026e095eb6350c13 348 SUPERFAMILY SSF55909 9 346 6.6E-103 T 29-03-2018 CSW12_RS10475 f5a9149ec72723f3026e095eb6350c13 348 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 11 345 4.6E-99 T 29-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CSW12_RS10475 f5a9149ec72723f3026e095eb6350c13 348 Gene3D G3DSA:3.75.10.10 2 348 4.9E-106 T 29-03-2018 CSW12_RS22165 aa0951711e149e443a49dad800049ff6 259 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 110 237 9.3E-48 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CSW12_RS22165 aa0951711e149e443a49dad800049ff6 259 Gene3D G3DSA:3.30.1380.10 88 250 5.1E-40 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS22165 aa0951711e149e443a49dad800049ff6 259 SUPERFAMILY SSF55166 93 246 5.23E-40 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS10525 c433cf7a287115c37a8e71e31f72d3e2 170 Pfam PF10901 Protein of unknown function (DUF2690) 36 147 8.5E-30 T 29-03-2018 IPR021224 Protein of unknown function DUF2690 CSW12_RS11355 1b4b41051205b19a7f4b9fa65b8bfa5f 292 Gene3D G3DSA:3.40.50.1580 26 292 2.9E-39 T 29-03-2018 CSW12_RS11355 1b4b41051205b19a7f4b9fa65b8bfa5f 292 Pfam PF01048 Phosphorylase superfamily 42 283 2.1E-36 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS11355 1b4b41051205b19a7f4b9fa65b8bfa5f 292 SUPERFAMILY SSF53167 42 270 2.49E-45 T 29-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CSW12_RS16455 6d2bf1dc8ff65fca7c771ab07c40552e 51 Pfam PF13067 Protein of unknown function (DUF3930) 1 51 5.7E-36 T 29-03-2018 IPR025172 Protein of unknown function DUF3930 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 8.4E-55 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 Gene3D G3DSA:1.20.140.10 218 376 3.2E-65 T 29-03-2018 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 7.0E-26 T 29-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 SUPERFAMILY SSF56645 1 239 2.23E-86 T 29-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 Gene3D G3DSA:1.10.540.10 1 119 3.2E-36 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 29-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 Gene3D G3DSA:2.40.110.10 120 217 3.3E-39 T 29-03-2018 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 PIRSF PIRSF016578 6 366 6.5E-22 T 29-03-2018 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.5E-37 T 29-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CSW12_RS26505 844b896a8c3600561a600c6746bea107 376 SUPERFAMILY SSF47203 226 376 4.99E-62 T 29-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CSW12_RS11050 0fbb8802c4e80d927cdd5959155a3676 355 Gene3D G3DSA:2.130.10.10 7 355 1.3E-45 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS11050 0fbb8802c4e80d927cdd5959155a3676 355 Pfam PF10282 Lactonase, 7-bladed beta-propeller 12 352 2.5E-134 T 29-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CSW12_RS11050 0fbb8802c4e80d927cdd5959155a3676 355 SUPERFAMILY SSF51004 19 354 3.14E-51 T 29-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CSW12_RS04060 bb4f624574309b42993fbc973bcaa985 41 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 4.4E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS04060 bb4f624574309b42993fbc973bcaa985 41 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 10 33 7.6E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS24550 a296a2678ae8be9483d1020634f1db05 78 Gene3D G3DSA:3.30.300.130 1 78 4.4E-29 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS24550 a296a2678ae8be9483d1020634f1db05 78 SUPERFAMILY SSF117916 2 77 2.45E-26 T 29-03-2018 IPR034904 Fe-S cluster assembly domain CSW12_RS24550 a296a2678ae8be9483d1020634f1db05 78 Pfam PF01106 NifU-like domain 11 75 5.0E-28 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CSW12_RS24550 a296a2678ae8be9483d1020634f1db05 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 77 4.0E-29 T 29-03-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 CSW12_RS14295 ed04563875d47917c90313bc3b8a8c6d 148 SUPERFAMILY SSF55811 4 114 9.48E-23 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS14295 ed04563875d47917c90313bc3b8a8c6d 148 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS14295 ed04563875d47917c90313bc3b8a8c6d 148 Pfam PF00293 NUDIX domain 7 115 5.1E-16 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS14295 ed04563875d47917c90313bc3b8a8c6d 148 Gene3D G3DSA:3.90.79.10 5 142 1.1E-19 T 29-03-2018 CSW12_RS14295 ed04563875d47917c90313bc3b8a8c6d 148 PRINTS PR00502 NUDIX hydrolase family signature 29 43 2.3E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS14295 ed04563875d47917c90313bc3b8a8c6d 148 PRINTS PR00502 NUDIX hydrolase family signature 43 58 2.3E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS15505 c7a71c417856bae23c9e4ac7a99981e7 380 Pfam PF03600 Citrate transporter 30 308 5.1E-17 T 29-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CSW12_RS01905 a1be01a76ca83cad2d72f2ba661421b5 218 Gene3D G3DSA:1.10.3720.10 3 218 1.7E-47 T 29-03-2018 CSW12_RS01905 a1be01a76ca83cad2d72f2ba661421b5 218 SUPERFAMILY SSF161098 13 199 4.06E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01905 a1be01a76ca83cad2d72f2ba661421b5 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 7.9E-21 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01905 a1be01a76ca83cad2d72f2ba661421b5 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 8.8E-27 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 SUPERFAMILY SSF52096 29 281 9.95E-84 T 29-03-2018 IPR029045 ClpP/crotonase-like domain CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 Pfam PF01039 Carboxyl transferase domain 62 241 6.0E-21 T 29-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 16 280 3.3E-129 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 Gene3D G3DSA:3.90.226.10 15 284 3.9E-70 T 29-03-2018 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 38.9 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 2.4E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 2.4E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 2.4E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 2.4E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS22635 5cd5c8d9719fd3ddc7912329a5db9b57 289 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 2.4E-38 T 29-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CSW12_RS26975 abaf21d34be81f5d52ea6dee4804fac9 143 Pfam PF03788 LrgA family 21 112 1.8E-23 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CSW12_RS26975 abaf21d34be81f5d52ea6dee4804fac9 143 Hamap MF_01141 Antiholin-like protein LrgA [lrgA]. 1 135 29.255 T 29-03-2018 IPR023736 Antiholin-like protein LrgA CSW12_RS02955 c3a961f1d58caee2e2a7b50d7109a952 249 SUPERFAMILY SSF52540 6 222 2.96E-56 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS02955 c3a961f1d58caee2e2a7b50d7109a952 249 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS02955 c3a961f1d58caee2e2a7b50d7109a952 249 SMART SM00382 31 207 1.8E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS02955 c3a961f1d58caee2e2a7b50d7109a952 249 Gene3D G3DSA:3.40.50.300 2 230 1.4E-54 T 29-03-2018 CSW12_RS02955 c3a961f1d58caee2e2a7b50d7109a952 249 Pfam PF00005 ABC transporter 23 157 1.3E-26 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS27400 37107fa7c9f8d0c5f8ac924210d631ad 183 Gene3D G3DSA:1.10.10.10 156 181 1.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27400 37107fa7c9f8d0c5f8ac924210d631ad 183 Pfam PF04545 Sigma-70, region 4 136 168 1.3E-6 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS27400 37107fa7c9f8d0c5f8ac924210d631ad 183 Gene3D G3DSA:1.10.10.10 123 155 1.1E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS27400 37107fa7c9f8d0c5f8ac924210d631ad 183 Pfam PF12677 Domain of unknown function (DUF3797) 54 107 5.5E-25 T 29-03-2018 IPR024256 Domain of unknown function DUF3797 CSW12_RS24785 18405b0f4c8693538091f1e9a84a1793 337 Pfam PF13303 Phosphotransferase system, EIIC 11 333 3.5E-101 T 29-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CSW12_RS05780 625acada3778454cea80c44d5ddb6eeb 261 Gene3D G3DSA:2.20.28.20 2 29 7.9E-6 T 29-03-2018 CSW12_RS05780 625acada3778454cea80c44d5ddb6eeb 261 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 1 129 5.0E-4 T 29-03-2018 CSW12_RS05780 625acada3778454cea80c44d5ddb6eeb 261 Pfam PF13240 zinc-ribbon domain 2 24 5.5E-6 T 29-03-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 CSW12_RS08265 fdb4e4e7cb446b6af2b7f84d043f88b8 87 Pfam PF02325 YGGT family 11 77 1.9E-24 T 29-03-2018 IPR003425 CCB3/YggT GO:0016020 CSW12_RS04405 eecc9c048fec9c9b10b7f22ab8eb2ace 208 PIRSF PIRSF006324 1 208 1.4E-59 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS04405 eecc9c048fec9c9b10b7f22ab8eb2ace 208 Pfam PF01810 LysE type translocator 14 206 2.6E-40 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS07710 3717f5cec6c69b52c4e8567a1c27ab1c 144 Pfam PF14040 Deoxyribonuclease NucA/NucB 46 130 1.5E-10 T 29-03-2018 IPR029476 Deoxyribonuclease NucA/NucB CSW12_RS08650 58870723be3cda9ec506486c182d3d0f 240 Gene3D G3DSA:3.40.1160.10 1 240 4.1E-44 T 29-03-2018 CSW12_RS08650 58870723be3cda9ec506486c182d3d0f 240 Pfam PF00696 Amino acid kinase family 7 217 4.4E-29 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS08650 58870723be3cda9ec506486c182d3d0f 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 4.1E-102 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CSW12_RS08650 58870723be3cda9ec506486c182d3d0f 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 44.816 T 29-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CSW12_RS08650 58870723be3cda9ec506486c182d3d0f 240 PIRSF PIRSF005650 1 240 4.4E-98 T 29-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CSW12_RS08650 58870723be3cda9ec506486c182d3d0f 240 SUPERFAMILY SSF53633 4 238 3.14E-74 T 29-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CSW12_RS25315 9ed5ecb7a2e81f4a0a647e88041f2d59 247 PIRSF PIRSF017388 2 247 2.7E-94 T 29-03-2018 IPR012354 Esterase/lipase GO:0052689 CSW12_RS25315 9ed5ecb7a2e81f4a0a647e88041f2d59 247 Pfam PF12146 Serine aminopeptidase, S33 17 229 5.7E-17 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS25315 9ed5ecb7a2e81f4a0a647e88041f2d59 247 Gene3D G3DSA:3.40.50.1820 1 247 1.1E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS25315 9ed5ecb7a2e81f4a0a647e88041f2d59 247 SUPERFAMILY SSF53474 12 246 4.3E-35 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS30860 5c0d54bf6566c6846d310a3ceb8502f5 412 SUPERFAMILY SSF53067 245 372 1.42E-5 T 29-03-2018 CSW12_RS30860 5c0d54bf6566c6846d310a3ceb8502f5 412 Gene3D G3DSA:3.30.420.40 6 223 5.0E-15 T 29-03-2018 CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 Gene3D G3DSA:1.20.1560.10 1 228 1.6E-11 T 29-03-2018 CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 SUPERFAMILY SSF90123 14 212 6.54E-15 T 29-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 SUPERFAMILY SSF52540 240 483 1.86E-70 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 ProSitePatterns PS00211 ABC transporters family signature. 385 399 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 Gene3D G3DSA:3.40.50.300 229 487 1.5E-65 T 29-03-2018 CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 SMART SM00382 268 459 6.5E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS10865 b1c90a4ba45338961270a8c58bf7bcd2 488 Pfam PF00005 ABC transporter 259 413 1.3E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS29750 5c4d497589a67c5657612a9d0db0d6c1 184 SUPERFAMILY SSF46955 8 129 2.93E-5 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS29750 5c4d497589a67c5657612a9d0db0d6c1 184 Pfam PF13411 MerR HTH family regulatory protein 9 75 9.3E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS29750 5c4d497589a67c5657612a9d0db0d6c1 184 Pfam PF13152 Protein of unknown function (DUF3967) 145 183 1.1E-8 T 29-03-2018 IPR025052 Domain of unknown function DUF3967 CSW12_RS29750 5c4d497589a67c5657612a9d0db0d6c1 184 Gene3D G3DSA:1.10.1660.10 3 179 1.5E-16 T 29-03-2018 CSW12_RS04995 9927e6bd72dea7b4137ea32d30e7219a 204 Gene3D G3DSA:1.10.287.620 6 93 1.2E-4 T 29-03-2018 CSW12_RS04995 9927e6bd72dea7b4137ea32d30e7219a 204 Pfam PF10737 Spore germination protein GerPC 23 198 8.3E-61 T 29-03-2018 IPR019673 Spore germination protein GerPC CSW12_RS12415 c5c194c3dd2c9907dcbad90f680c38fd 149 Pfam PF13302 Acetyltransferase (GNAT) domain 48 134 1.9E-22 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS12415 c5c194c3dd2c9907dcbad90f680c38fd 149 Gene3D G3DSA:3.40.630.30 35 146 8.5E-19 T 29-03-2018 CSW12_RS12415 c5c194c3dd2c9907dcbad90f680c38fd 149 SUPERFAMILY SSF55729 2 136 6.07E-30 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS21720 03012ac1048f448769603602fd030141 86 Pfam PF02699 Preprotein translocase subunit 7 81 9.1E-30 T 29-03-2018 IPR003849 Preprotein translocase YajC CSW12_RS21720 03012ac1048f448769603602fd030141 86 SMART SM01323 3 84 7.0E-41 T 29-03-2018 IPR003849 Preprotein translocase YajC CSW12_RS21720 03012ac1048f448769603602fd030141 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 5 25 7.0E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC CSW12_RS21720 03012ac1048f448769603602fd030141 86 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 7.0E-15 T 29-03-2018 IPR003849 Preprotein translocase YajC CSW12_RS21720 03012ac1048f448769603602fd030141 86 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 84 7.1E-30 T 29-03-2018 IPR003849 Preprotein translocase YajC CSW12_RS16430 6ce4214dad17fba2adac38addc84f75b 213 Pfam PF01569 PAP2 superfamily 97 205 8.5E-22 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS16430 6ce4214dad17fba2adac38addc84f75b 213 SMART SM00014 87 200 6.5E-25 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS16430 6ce4214dad17fba2adac38addc84f75b 213 Gene3D G3DSA:1.20.144.10 33 210 5.8E-28 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS16430 6ce4214dad17fba2adac38addc84f75b 213 SUPERFAMILY SSF48317 5 205 1.7E-39 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS00535 7d9e9bfd233e0701c36762a50bb675b7 473 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 9 455 1.7E-144 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CSW12_RS00535 7d9e9bfd233e0701c36762a50bb675b7 473 Pfam PF03553 Na+/H+ antiporter family 158 450 3.9E-62 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CSW12_RS18400 1e03e945e4071db7da63cd6bc26cbd50 207 Pfam PF00583 Acetyltransferase (GNAT) family 49 181 8.0E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS18400 1e03e945e4071db7da63cd6bc26cbd50 207 Gene3D G3DSA:3.40.630.30 17 206 1.4E-20 T 29-03-2018 CSW12_RS18400 1e03e945e4071db7da63cd6bc26cbd50 207 SUPERFAMILY SSF55729 30 200 8.97E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS14720 3b4c8e120bd8b93b39dc40816cf655ed 164 Pfam PF11667 Putative zincin peptidase 55 154 2.5E-16 T 29-03-2018 IPR021683 Putative zincin peptidase CSW12_RS05190 fc6c81b73a410976a63a11237de9c31b 127 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 7 120 3.5E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CSW12_RS05190 fc6c81b73a410976a63a11237de9c31b 127 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 20 86 3.2E-6 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CSW12_RS02190 c411a63beac0c4f4eb2be04973ca2786 114 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 7 78 1.1E-6 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CSW12_RS13115 3cba675b7fc903f20393ed904e38ce49 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 2.0E-21 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13115 3cba675b7fc903f20393ed904e38ce49 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 2.4E-24 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS22665 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Gene3D G3DSA:3.90.1640.10 1 197 3.6E-42 T 29-03-2018 CSW12_RS22665 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Pfam PF01368 DHH family 15 153 9.3E-14 T 29-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CSW12_RS22665 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 Pfam PF02272 DHHA1 domain 179 308 9.6E-14 T 29-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CSW12_RS22665 e6b51bd03f8a6e694f877bb2c7c5f5bb 310 SUPERFAMILY SSF64182 13 300 3.14E-74 T 29-03-2018 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SMART SM00065 24 173 2.6E-14 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SUPERFAMILY SSF47384 454 516 3.34E-13 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Pfam PF13185 GAF domain 23 164 1.3E-10 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SUPERFAMILY SSF55874 519 665 3.27E-29 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SMART SM00387 563 669 3.0E-23 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 601 615 6.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 648 6.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 619 629 6.9E-7 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Gene3D G3DSA:3.30.450.20 333 447 5.7E-16 T 29-03-2018 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Gene3D G3DSA:3.30.565.10 522 672 2.1E-30 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 344 449 1.3E-5 T 29-03-2018 IPR000014 PAS domain CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SUPERFAMILY SSF55781 6 189 2.18E-21 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Gene3D G3DSA:1.10.287.130 448 517 8.3E-14 T 29-03-2018 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SMART SM00388 457 522 1.6E-12 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Pfam PF00512 His Kinase A (phospho-acceptor) domain 459 516 5.1E-14 T 29-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Gene3D G3DSA:3.30.450.40 4 191 6.0E-25 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Gene3D G3DSA:3.30.450.40 254 332 8.4E-5 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 SUPERFAMILY SSF55785 348 451 1.41E-11 T 29-03-2018 IPR000014 PAS domain CSW12_RS27135 fa1483b860ede7907a1feecd2fe2d132 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 566 666 1.2E-14 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS10385 90086c6aab6743143a980dab2691c1be 115 Pfam PF14079 Domain of unknown function (DUF4260) 3 114 2.6E-43 T 29-03-2018 IPR025356 Protein of unknown function DUF4260 CSW12_RS06650 038fad7d53f545d398603fc6a2600ef7 55 Pfam PF13217 Protein of unknown function (DUF4025) 4 48 4.1E-16 T 29-03-2018 IPR025100 Protein of unknown function DUF4025 CSW12_RS08190 282eab52c50e154a8632df13439c68e2 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 320 2.9E-120 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS08190 282eab52c50e154a8632df13439c68e2 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS08190 282eab52c50e154a8632df13439c68e2 324 Pfam PF00953 Glycosyl transferase family 4 83 248 1.0E-37 T 29-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CSW12_RS08190 282eab52c50e154a8632df13439c68e2 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 59 4.3E-5 T 29-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS08190 282eab52c50e154a8632df13439c68e2 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.104 T 29-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CSW12_RS27650 ab46386bdbc2eca4073eb994aa2be081 161 Gene3D G3DSA:2.40.50.140 1 80 3.0E-28 T 29-03-2018 CSW12_RS27650 ab46386bdbc2eca4073eb994aa2be081 161 Pfam PF00575 S1 RNA binding domain 4 74 3.4E-22 T 29-03-2018 IPR003029 S1 domain GO:0003676 CSW12_RS27650 ab46386bdbc2eca4073eb994aa2be081 161 SMART SM00316 4 74 6.8E-27 T 29-03-2018 IPR022967 RNA-binding domain, S1 CSW12_RS27650 ab46386bdbc2eca4073eb994aa2be081 161 SUPERFAMILY SSF50249 4 81 1.39E-24 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS08370 ab68c8aae2cd04b5368b5db02d8fc61e 174 SUPERFAMILY SSF109854 7 167 4.58E-37 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS08370 ab68c8aae2cd04b5368b5db02d8fc61e 174 Pfam PF04978 Protein of unknown function (DUF664) 18 164 1.0E-8 T 29-03-2018 IPR007061 Protein of unknown function DUF664 CSW12_RS08370 ab68c8aae2cd04b5368b5db02d8fc61e 174 Gene3D G3DSA:1.20.120.450 11 166 1.2E-18 T 29-03-2018 CSW12_RS07460 315d4d83596e81cf042d60b4230567c3 205 Pfam PF00881 Nitroreductase family 12 183 1.3E-29 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS07460 315d4d83596e81cf042d60b4230567c3 205 Gene3D G3DSA:3.40.109.10 1 205 1.1E-43 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS07460 315d4d83596e81cf042d60b4230567c3 205 SUPERFAMILY SSF55469 5 203 9.55E-52 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS07645 1b006371f66796c1aa496ee681f25b9a 169 Pfam PF00106 short chain dehydrogenase 17 116 2.1E-21 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07645 1b006371f66796c1aa496ee681f25b9a 169 Gene3D G3DSA:3.40.50.720 9 126 2.8E-24 T 29-03-2018 CSW12_RS07645 1b006371f66796c1aa496ee681f25b9a 169 SUPERFAMILY SSF51735 10 120 3.95E-27 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07645 1b006371f66796c1aa496ee681f25b9a 169 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 9.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07645 1b006371f66796c1aa496ee681f25b9a 169 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 9.7E-7 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS23185 17da42d7c3db96c34784723ad704ddcf 92 Pfam PF14165 YtzH-like protein 3 88 1.4E-38 T 29-03-2018 IPR025547 YtzH-like protein CSW12_RS12075 9a284891afe9a0554aac5188fbbacf54 236 Gene3D G3DSA:3.40.50.1820 163 236 3.7E-5 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12075 9a284891afe9a0554aac5188fbbacf54 236 Gene3D G3DSA:3.40.50.1820 57 162 1.5E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12075 9a284891afe9a0554aac5188fbbacf54 236 SUPERFAMILY SSF53474 55 203 3.48E-21 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12075 9a284891afe9a0554aac5188fbbacf54 236 Pfam PF12695 Alpha/beta hydrolase family 60 222 7.9E-69 T 29-03-2018 IPR029059 Alpha/beta hydrolase fold-5 CSW12_RS06135 07f87bd18027171dda08c0af2ab3f000 449 Pfam PF02386 Cation transport protein 42 429 1.1E-59 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CSW12_RS07160 e99f562682219459d82cbd0d29b4a3bf 158 SUPERFAMILY SSF47598 106 146 8.34E-5 T 29-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CSW12_RS07160 e99f562682219459d82cbd0d29b4a3bf 158 Gene3D G3DSA:1.10.1220.10 101 153 4.2E-11 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CSW12_RS07160 e99f562682219459d82cbd0d29b4a3bf 158 Pfam PF12651 Ribbon-helix-helix domain 106 149 1.2E-11 T 29-03-2018 CSW12_RS24630 7481d4bc67e0617fb0c405d4cb333a23 165 SUPERFAMILY SSF55174 115 163 1.0E-7 T 29-03-2018 CSW12_RS24630 7481d4bc67e0617fb0c405d4cb333a23 165 Gene3D G3DSA:3.10.290.10 90 165 3.8E-9 T 29-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CSW12_RS01815 5a4830971cf53a671d40fde87068c9a8 321 SUPERFAMILY SSF51735 1 313 1.7E-55 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01815 5a4830971cf53a671d40fde87068c9a8 321 Gene3D G3DSA:3.40.50.720 1 312 2.6E-35 T 29-03-2018 CSW12_RS01815 5a4830971cf53a671d40fde87068c9a8 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 240 2.1E-27 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS07600 f06a5dee70c51bc09daebeb96f64110e 292 SUPERFAMILY SSF56059 88 281 1.56E-20 T 29-03-2018 CSW12_RS07600 f06a5dee70c51bc09daebeb96f64110e 292 Gene3D G3DSA:3.30.1490.20 102 169 0.002 T 29-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CSW12_RS07600 f06a5dee70c51bc09daebeb96f64110e 292 Gene3D G3DSA:3.30.470.20 170 276 9.6E-18 T 29-03-2018 CSW12_RS07600 f06a5dee70c51bc09daebeb96f64110e 292 Gene3D G3DSA:3.40.50.20 3 101 5.7E-12 T 29-03-2018 CSW12_RS07600 f06a5dee70c51bc09daebeb96f64110e 292 Pfam PF08443 RimK-like ATP-grasp domain 96 273 3.4E-16 T 29-03-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 CSW12_RS23780 158d411d0358f72795ae38649bc0c138 75 SUPERFAMILY SSF50037 3 73 5.8E-15 T 29-03-2018 IPR008988 Transcriptional repressor, C-terminal CSW12_RS23780 158d411d0358f72795ae38649bc0c138 75 Pfam PF04023 FeoA domain 1 73 3.2E-15 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CSW12_RS23780 158d411d0358f72795ae38649bc0c138 75 Gene3D G3DSA:2.30.30.90 1 75 2.9E-15 T 29-03-2018 CSW12_RS23780 158d411d0358f72795ae38649bc0c138 75 SMART SM00899 1 74 7.3E-18 T 29-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CSW12_RS16720 0470b2b748a12156d97c607b90679dd2 704 SUPERFAMILY SSF56349 485 528 1.0E-7 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS16720 0470b2b748a12156d97c607b90679dd2 704 Gene3D G3DSA:1.10.150.130 200 311 0.001 T 29-03-2018 IPR023109 Integrase/recombinase, N-terminal CSW12_RS16720 0470b2b748a12156d97c607b90679dd2 704 Gene3D G3DSA:1.10.443.10 312 536 1.1E-8 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS26135 3e2d9db3c2ceffb3026ae4110c8436af 593 SUPERFAMILY SSF51735 268 531 5.14E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS26135 3e2d9db3c2ceffb3026ae4110c8436af 593 SUPERFAMILY SSF53335 93 293 2.33E-16 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS26135 3e2d9db3c2ceffb3026ae4110c8436af 593 Gene3D G3DSA:3.40.50.720 124 251 4.0E-31 T 29-03-2018 CSW12_RS26135 3e2d9db3c2ceffb3026ae4110c8436af 593 Gene3D G3DSA:3.40.50.720 263 590 1.5E-64 T 29-03-2018 CSW12_RS26135 3e2d9db3c2ceffb3026ae4110c8436af 593 Pfam PF13727 CoA-binding domain 62 225 4.5E-19 T 29-03-2018 CSW12_RS26135 3e2d9db3c2ceffb3026ae4110c8436af 593 Pfam PF02719 Polysaccharide biosynthesis protein 270 551 8.2E-124 T 29-03-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain CSW12_RS22105 803ce30f3b0fe74df5f39b7411befdd9 413 SUPERFAMILY SSF51556 66 370 1.36E-74 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS22105 803ce30f3b0fe74df5f39b7411befdd9 413 Pfam PF07969 Amidohydrolase family 55 401 5.0E-37 T 29-03-2018 IPR013108 Amidohydrolase 3 CSW12_RS22105 803ce30f3b0fe74df5f39b7411befdd9 413 Gene3D G3DSA:3.20.20.140 81 352 4.9E-32 T 29-03-2018 CSW12_RS22105 803ce30f3b0fe74df5f39b7411befdd9 413 Gene3D G3DSA:2.30.40.10 2 80 5.1E-8 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 SUPERFAMILY SSF46785 8 143 4.97E-27 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 Gene3D G3DSA:1.10.10.10 1 148 3.7E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 SMART SM00347 29 129 1.2E-14 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 29-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 Pfam PF12802 MarR family 35 92 5.1E-12 T 29-03-2018 CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 9.2E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS15665 456ea348d78a23466520dabcd3370c69 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 9.2E-5 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS16435 8d06ed162c6260f68aca97fac3f6d143 251 Pfam PF07070 SpoOM protein 2 211 1.1E-75 T 29-03-2018 IPR009776 Sporulation stage 0, protein M CSW12_RS12880 d54fe1c26609cd19f353f04ea422aeec 176 Pfam PF00857 Isochorismatase family 4 144 2.2E-40 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS12880 d54fe1c26609cd19f353f04ea422aeec 176 SUPERFAMILY SSF52499 2 158 1.02E-48 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS12880 d54fe1c26609cd19f353f04ea422aeec 176 Gene3D G3DSA:3.40.50.850 1 174 7.2E-47 T 29-03-2018 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 PIRSF PIRSF000193 3 271 1.8E-80 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 Gene3D G3DSA:3.40.50.720 1 166 5.8E-24 T 29-03-2018 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 268 7.9E-84 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 1.2E-17 T 29-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 164 268 1.6E-36 T 29-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 Gene3D G3DSA:1.10.3730.10 167 273 3.9E-40 T 29-03-2018 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 SUPERFAMILY SSF48179 163 271 1.87E-35 T 29-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 SUPERFAMILY SSF51735 5 162 5.34E-29 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 224 246 - T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS20230 7bae73aba3eb5ed448dbb0a2fbe65299 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 268 26.276 T 29-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 SUPERFAMILY SSF51306 27 180 3.14E-53 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 ProSitePatterns PS00761 Signal peptidases I signature 3. 142 155 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 12 177 1.7E-53 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 Gene3D G3DSA:2.10.109.10 25 187 3.1E-46 T 29-03-2018 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 2.1E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 91 2.1E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 137 156 2.1E-20 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 ProSitePatterns PS00760 Signal peptidases I lysine active site. 81 93 - T 29-03-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CSW12_RS04960 ba2434222c685d99ef05b0fc024c4761 187 Pfam PF00717 Peptidase S24-like 36 103 4.3E-22 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS00780 5331328b086c800847ce724fc642b0eb 437 TIGRFAM TIGR00770 Dcu: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family 5 436 3.7E-173 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 CSW12_RS00780 5331328b086c800847ce724fc642b0eb 437 PIRSF PIRSF004539 1 437 1.5E-192 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 CSW12_RS00780 5331328b086c800847ce724fc642b0eb 437 Pfam PF03605 Anaerobic c4-dicarboxylate membrane transporter 5 369 2.5E-158 T 29-03-2018 IPR004668 Anaerobic c4-dicarboxylate membrane transporter GO:0015556|GO:0015740|GO:0016021 CSW12_RS15145 2f7dc2ce71de62eda2d5d088ca5e21a3 342 SUPERFAMILY SSF102114 84 234 1.23E-5 T 29-03-2018 CSW12_RS15145 2f7dc2ce71de62eda2d5d088ca5e21a3 342 Gene3D G3DSA:3.20.20.70 22 340 5.1E-10 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS15145 2f7dc2ce71de62eda2d5d088ca5e21a3 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 5.4E-153 T 29-03-2018 IPR023897 Spore photoproduct lyase GO:0003913 CSW12_RS22285 3d57e626ebc75b69391a33325108b38a 307 Pfam PF00005 ABC transporter 21 161 4.3E-32 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS22285 3d57e626ebc75b69391a33325108b38a 307 SUPERFAMILY SSF52540 3 222 2.09E-57 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22285 3d57e626ebc75b69391a33325108b38a 307 Gene3D G3DSA:3.40.50.300 1 291 2.7E-55 T 29-03-2018 CSW12_RS22285 3d57e626ebc75b69391a33325108b38a 307 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS22285 3d57e626ebc75b69391a33325108b38a 307 SMART SM00382 29 210 3.5E-12 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS14915 784fae881b71d2d4d51616486a5d666d 408 SMART SM00342 319 402 8.9E-27 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS14915 784fae881b71d2d4d51616486a5d666d 408 Pfam PF12833 Helix-turn-helix domain 325 403 1.4E-18 T 29-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CSW12_RS14915 784fae881b71d2d4d51616486a5d666d 408 Gene3D G3DSA:1.10.10.60 353 406 1.0E-10 T 29-03-2018 CSW12_RS14915 784fae881b71d2d4d51616486a5d666d 408 Gene3D G3DSA:1.10.10.60 293 352 1.4E-13 T 29-03-2018 CSW12_RS14915 784fae881b71d2d4d51616486a5d666d 408 SUPERFAMILY SSF46689 302 353 5.38E-7 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS14915 784fae881b71d2d4d51616486a5d666d 408 SUPERFAMILY SSF46689 356 406 3.94E-11 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 SUPERFAMILY SSF103473 13 455 6.8E-39 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 18 214 5.7E-53 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 239 460 4.6E-45 T 29-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 Pfam PF00854 POT family 94 214 4.6E-27 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 Pfam PF00854 POT family 243 428 6.7E-33 T 29-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 Gene3D G3DSA:1.20.1250.20 15 220 7.9E-24 T 29-03-2018 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 Gene3D G3DSA:1.20.1250.20 230 457 7.2E-18 T 29-03-2018 CSW12_RS01780 8b1c5ff37376c80e7c1b21351892884b 461 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 156 168 - T 29-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CSW12_RS00270 a417adaf7670226c40b764206c1617fe 128 Pfam PF01844 HNH endonuclease 65 111 3.9E-13 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CSW12_RS00270 a417adaf7670226c40b764206c1617fe 128 Gene3D G3DSA:3.40.1800.10 44 120 3.6E-15 T 29-03-2018 CSW12_RS00270 a417adaf7670226c40b764206c1617fe 128 SMART SM00507 52 107 2.0E-8 T 29-03-2018 IPR003615 HNH nuclease CSW12_RS25190 fe28978080f9ea09daba1a4eadd978ae 118 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 112 1.1E-23 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CSW12_RS25190 fe28978080f9ea09daba1a4eadd978ae 118 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 18.851 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CSW12_RS25070 beb7f57bf66c30a904fbccac4b274f8f 107 PIRSF PIRSF036521 1 107 4.7E-54 T 29-03-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related CSW12_RS25070 beb7f57bf66c30a904fbccac4b274f8f 107 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 29 102 1.8E-11 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CSW12_RS25070 beb7f57bf66c30a904fbccac4b274f8f 107 Gene3D G3DSA:1.10.287.1080 1 107 4.8E-16 T 29-03-2018 CSW12_RS25070 beb7f57bf66c30a904fbccac4b274f8f 107 SUPERFAMILY SSF101386 1 104 1.54E-24 T 29-03-2018 CSW12_RS11480 f5dbb9c6695fe54662742f698b1ed4d9 299 SUPERFAMILY SSF53474 6 299 4.69E-61 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11480 f5dbb9c6695fe54662742f698b1ed4d9 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 9.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS11480 f5dbb9c6695fe54662742f698b1ed4d9 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 9.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS11480 f5dbb9c6695fe54662742f698b1ed4d9 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 9.0E-9 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS11480 f5dbb9c6695fe54662742f698b1ed4d9 299 Pfam PF00561 alpha/beta hydrolase fold 31 285 1.5E-28 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS11480 f5dbb9c6695fe54662742f698b1ed4d9 299 Gene3D G3DSA:3.40.50.1820 2 299 1.0E-47 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.5E-39 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 256 1.8E-64 T 29-03-2018 CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.8E-12 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 258 7.8E-111 T 29-03-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 SUPERFAMILY SSF51735 4 257 6.58E-82 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 Gene3D G3DSA:3.40.50.720 1 41 1.4E-9 T 29-03-2018 CSW12_RS07535 cd35505d1577fde7682772b8f34937b4 258 Gene3D G3DSA:3.40.50.720 42 258 1.2E-60 T 29-03-2018 CSW12_RS31175 8c1209380b5d45cdad3d3af13aa5572f 91 SUPERFAMILY SSF143011 3 90 1.22E-5 T 29-03-2018 IPR035095 Toxin RelE-like domain CSW12_RS31175 8c1209380b5d45cdad3d3af13aa5572f 91 Gene3D G3DSA:3.30.2310.20 1 91 1.8E-8 T 29-03-2018 CSW12_RS31175 8c1209380b5d45cdad3d3af13aa5572f 91 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 8 91 2.5E-16 T 29-03-2018 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin CSW12_RS14200 6640acc61ed5064bd13b011d89951bb7 157 Pfam PF13508 Acetyltransferase (GNAT) domain 59 137 2.8E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS14200 6640acc61ed5064bd13b011d89951bb7 157 Gene3D G3DSA:3.40.630.30 2 157 7.2E-21 T 29-03-2018 CSW12_RS14200 6640acc61ed5064bd13b011d89951bb7 157 SUPERFAMILY SSF55729 1 142 2.27E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13345 c4f28264eca922702d1585c39a053a29 332 SUPERFAMILY SSF56112 15 307 1.09E-43 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS13345 c4f28264eca922702d1585c39a053a29 332 Gene3D G3DSA:3.90.1200.10 120 325 3.1E-15 T 29-03-2018 CSW12_RS13345 c4f28264eca922702d1585c39a053a29 332 Pfam PF01636 Phosphotransferase enzyme family 34 267 3.6E-21 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS13345 c4f28264eca922702d1585c39a053a29 332 Gene3D G3DSA:3.30.200.20 2 113 5.1E-12 T 29-03-2018 CSW12_RS21210 5c032b183809b61a6efa59f0264ef2af 124 Gene3D G3DSA:1.10.10.10 26 124 3.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21210 5c032b183809b61a6efa59f0264ef2af 124 Pfam PF01638 HxlR-like helix-turn-helix 28 117 2.0E-33 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS21210 5c032b183809b61a6efa59f0264ef2af 124 SUPERFAMILY SSF46785 16 119 1.52E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS15545 c210289974fb56eb599d762140f95d63 210 Gene3D G3DSA:3.40.50.1110 14 205 4.9E-34 T 29-03-2018 CSW12_RS15545 c210289974fb56eb599d762140f95d63 210 SUPERFAMILY SSF52266 16 204 2.29E-35 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS15545 c210289974fb56eb599d762140f95d63 210 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 21 193 4.8E-24 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS13650 8eb29dbcd95d22c66a31c5a3222bafc2 170 Pfam PF13420 Acetyltransferase (GNAT) domain 2 153 5.8E-24 T 29-03-2018 CSW12_RS13650 8eb29dbcd95d22c66a31c5a3222bafc2 170 Gene3D G3DSA:3.40.630.30 1 167 7.8E-33 T 29-03-2018 CSW12_RS13650 8eb29dbcd95d22c66a31c5a3222bafc2 170 SUPERFAMILY SSF55729 1 163 9.35E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS11495 ce4a773ed195e5d1ad6cb5e5f5bbca70 66 Pfam PF14044 NETI protein 9 64 2.3E-30 T 29-03-2018 IPR025930 NETI protein CSW12_RS22540 ab2965f66a95293e1d6905a1f330d222 200 Gene3D G3DSA:3.40.50.300 2 198 4.1E-47 T 29-03-2018 CSW12_RS22540 ab2965f66a95293e1d6905a1f330d222 200 SUPERFAMILY SSF52540 1 194 5.77E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22540 ab2965f66a95293e1d6905a1f330d222 200 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 29.859 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CSW12_RS22540 ab2965f66a95293e1d6905a1f330d222 200 Pfam PF01121 Dephospho-CoA kinase 4 182 4.7E-69 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CSW12_RS22540 ab2965f66a95293e1d6905a1f330d222 200 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 1.1E-69 T 29-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CSW12_RS06155 aa695b1b70c44fc979326607121cffd7 358 Gene3D G3DSA:3.40.190.10 155 312 6.0E-36 T 29-03-2018 CSW12_RS06155 aa695b1b70c44fc979326607121cffd7 358 SUPERFAMILY SSF53850 40 348 1.01E-70 T 29-03-2018 CSW12_RS06155 aa695b1b70c44fc979326607121cffd7 358 PIRSF PIRSF002825 1 351 9.9E-94 T 29-03-2018 IPR026045 Ferric binding protein CSW12_RS06155 aa695b1b70c44fc979326607121cffd7 358 Pfam PF13343 Bacterial extracellular solute-binding protein 90 334 1.6E-31 T 29-03-2018 CSW12_RS06155 aa695b1b70c44fc979326607121cffd7 358 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 8 355 6.9E-163 T 29-03-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative CSW12_RS06155 aa695b1b70c44fc979326607121cffd7 358 Gene3D G3DSA:3.40.190.10 39 154 6.2E-10 T 29-03-2018 CSW12_RS07795 6ba8149bd70e673248c901d5fd62a254 78 Gene3D G3DSA:3.40.30.10 1 78 8.1E-23 T 29-03-2018 CSW12_RS07795 6ba8149bd70e673248c901d5fd62a254 78 SUPERFAMILY SSF52833 2 76 9.95E-18 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS07795 6ba8149bd70e673248c901d5fd62a254 78 Pfam PF00462 Glutaredoxin 4 63 4.3E-15 T 29-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CSW12_RS07795 6ba8149bd70e673248c901d5fd62a254 78 TIGRFAM TIGR02196 GlrX_YruB: glutaredoxin-like protein, YruB-family 3 76 4.4E-31 T 29-03-2018 IPR011911 Glutaredoxin-like protein, YruB CSW12_RS23595 6d3ec561a955b49ebc86ba0d25445ae9 861 Pfam PF13731 WxL domain surface cell wall-binding 721 804 1.3E-6 T 29-03-2018 IPR027994 WxL domain CSW12_RS15925 1d9e7a0500933294d9a3be05f14e5b62 213 Gene3D G3DSA:3.40.50.300 2 211 1.8E-15 T 29-03-2018 CSW12_RS15925 1d9e7a0500933294d9a3be05f14e5b62 213 SUPERFAMILY SSF52540 3 158 8.34E-13 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS27620 33e19e23ebb903b1fae1ae40560c73fa 533 PIRSF PIRSF038958 4 527 3.0E-85 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CSW12_RS27620 33e19e23ebb903b1fae1ae40560c73fa 533 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 510 9.3E-29 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CSW12_RS27620 33e19e23ebb903b1fae1ae40560c73fa 533 Pfam PF01943 Polysaccharide biosynthesis protein 9 307 1.1E-38 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS13095 265a0d466b0a5dbe916e45954cedde11 361 Pfam PF01594 AI-2E family transporter 18 348 6.7E-84 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CSW12_RS21275 99d6fdff333de01242cf2d1c7e1b51e8 249 Pfam PF13649 Methyltransferase domain 40 135 3.6E-19 T 29-03-2018 CSW12_RS21275 99d6fdff333de01242cf2d1c7e1b51e8 249 Gene3D G3DSA:2.20.25.110 143 206 4.4E-23 T 29-03-2018 CSW12_RS21275 99d6fdff333de01242cf2d1c7e1b51e8 249 SUPERFAMILY SSF53335 3 247 2.07E-52 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS21275 99d6fdff333de01242cf2d1c7e1b51e8 249 Gene3D G3DSA:3.40.50.150 2 138 4.8E-23 T 29-03-2018 CSW12_RS02250 fc9fbf67e79d4aa18c25066a49ceb6fb 141 Pfam PF05105 Bacteriophage holin family 18 127 3.1E-39 T 29-03-2018 IPR006480 Bacteriophage holin family CSW12_RS02250 fc9fbf67e79d4aa18c25066a49ceb6fb 141 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 13 137 5.5E-31 T 29-03-2018 IPR006480 Bacteriophage holin family CSW12_RS17885 58484dd27fc030f36c1d5421ea9b0df3 386 Pfam PF01841 Transglutaminase-like superfamily 139 232 4.6E-14 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS17885 58484dd27fc030f36c1d5421ea9b0df3 386 SMART SM00460 179 235 1.1E-7 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS17885 58484dd27fc030f36c1d5421ea9b0df3 386 SUPERFAMILY SSF54001 135 270 6.11E-24 T 29-03-2018 CSW12_RS21400 0a37d2c3e4d8e6b786181c4581109fc6 40 Pfam PF13215 Protein of unknown function (DUF4023) 1 38 4.9E-21 T 29-03-2018 IPR025097 Protein of unknown function DUF4023 CSW12_RS17875 93534f0a1dd27e8e9aca17aa51c49a02 153 Pfam PF00293 NUDIX domain 22 142 3.1E-22 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS17875 93534f0a1dd27e8e9aca17aa51c49a02 153 Gene3D G3DSA:3.90.79.10 1 150 8.4E-32 T 29-03-2018 CSW12_RS17875 93534f0a1dd27e8e9aca17aa51c49a02 153 SUPERFAMILY SSF55811 4 147 1.3E-34 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS17875 93534f0a1dd27e8e9aca17aa51c49a02 153 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS17875 93534f0a1dd27e8e9aca17aa51c49a02 153 PRINTS PR00502 NUDIX hydrolase family signature 58 73 6.1E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS17875 93534f0a1dd27e8e9aca17aa51c49a02 153 PRINTS PR00502 NUDIX hydrolase family signature 44 58 6.1E-7 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS23290 eed8725df6eb2c9cda93753fc69ee941 154 Pfam PF02391 MoaE protein 10 119 1.6E-35 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23290 eed8725df6eb2c9cda93753fc69ee941 154 Gene3D G3DSA:3.90.1170.40 2 145 5.2E-47 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS23290 eed8725df6eb2c9cda93753fc69ee941 154 SUPERFAMILY SSF54690 4 138 9.29E-47 T 29-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CSW12_RS02445 681ef851c2e64cf044fb680a8a6f217f 64 Pfam PF01844 HNH endonuclease 1 47 1.8E-8 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CSW12_RS02445 681ef851c2e64cf044fb680a8a6f217f 64 Gene3D G3DSA:3.40.1800.10 1 58 1.4E-6 T 29-03-2018 CSW12_RS04755 92d15eacc2b212bc68676357be43e220 244 SUPERFAMILY SSF56281 1 242 6.55E-57 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS04755 92d15eacc2b212bc68676357be43e220 244 Pfam PF12706 Beta-lactamase superfamily domain 30 211 2.0E-21 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS04755 92d15eacc2b212bc68676357be43e220 244 Gene3D G3DSA:3.60.15.10 1 244 7.2E-51 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS04755 92d15eacc2b212bc68676357be43e220 244 SMART SM00849 18 211 1.4E-11 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Gene3D G3DSA:3.30.830.10 11 219 1.3E-64 T 29-03-2018 CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 SUPERFAMILY SSF63411 228 400 3.36E-45 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 5.9E-51 T 29-03-2018 IPR011765 Peptidase M16, N-terminal CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Gene3D G3DSA:3.30.830.10 220 407 1.2E-41 T 29-03-2018 CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 29-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 SUPERFAMILY SSF63411 3 204 3.51E-64 T 29-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CSW12_RS08755 5b59c6b39b1801c421a51ceb3bc2cfbb 413 Pfam PF05193 Peptidase M16 inactive domain 166 338 1.3E-41 T 29-03-2018 IPR007863 Peptidase M16, C-terminal CSW12_RS11265 144257e844ec7a9bc68dd7e66538dbea 241 SUPERFAMILY SSF52540 1 225 3.29E-58 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11265 144257e844ec7a9bc68dd7e66538dbea 241 Gene3D G3DSA:3.40.50.300 1 236 2.9E-60 T 29-03-2018 CSW12_RS11265 144257e844ec7a9bc68dd7e66538dbea 241 Pfam PF00005 ABC transporter 19 161 3.3E-27 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS11265 144257e844ec7a9bc68dd7e66538dbea 241 SMART SM00382 27 211 2.9E-8 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS11265 144257e844ec7a9bc68dd7e66538dbea 241 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS18350 03b3f8ec26ca1fdbdb241990e5acfce7 159 PIRSF PIRSF021441 1 158 1.2E-67 T 29-03-2018 IPR031306 CcdC protein CSW12_RS18350 03b3f8ec26ca1fdbdb241990e5acfce7 159 Pfam PF07301 Protein of unknown function (DUF1453) 5 148 6.6E-58 T 29-03-2018 IPR009916 Protein of unknown function DUF1453 CSW12_RS03105 15df9ddf7fd89a9204680b759e1e70c7 170 Gene3D G3DSA:3.40.190.10 1 161 6.1E-5 T 29-03-2018 CSW12_RS03105 15df9ddf7fd89a9204680b759e1e70c7 170 Pfam PF13798 Protein of unknown function with PCYCGC motif 9 168 7.2E-73 T 29-03-2018 IPR025673 Protein of unknown function with PCYCGC motif CSW12_RS21510 20a3856a80a5f8d9a345a4eabca28601 212 SUPERFAMILY SSF53335 8 199 7.63E-32 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS21510 20a3856a80a5f8d9a345a4eabca28601 212 Pfam PF08241 Methyltransferase domain 50 143 2.2E-14 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS21510 20a3856a80a5f8d9a345a4eabca28601 212 Hamap MF_02100 Uncharacterized methyltransferase . 2 212 45.639 T 29-03-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 CSW12_RS21510 20a3856a80a5f8d9a345a4eabca28601 212 Gene3D G3DSA:3.40.50.150 24 212 1.1E-37 T 29-03-2018 CSW12_RS19055 e6a484f45366241da51aa6693dd7f03a 275 SUPERFAMILY SSF81606 101 237 2.49E-6 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS19055 e6a484f45366241da51aa6693dd7f03a 275 Pfam PF13672 Protein phosphatase 2C 126 238 6.2E-8 T 29-03-2018 CSW12_RS19055 e6a484f45366241da51aa6693dd7f03a 275 Gene3D G3DSA:3.60.40.10 40 262 5.0E-9 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS13200 0959970574a497b48d220196f61d0e83 400 Gene3D G3DSA:1.20.1250.20 1 197 4.0E-21 T 29-03-2018 CSW12_RS13200 0959970574a497b48d220196f61d0e83 400 Gene3D G3DSA:1.20.1250.20 202 398 6.5E-20 T 29-03-2018 CSW12_RS13200 0959970574a497b48d220196f61d0e83 400 Pfam PF05977 Transmembrane secretion effector 9 311 1.0E-14 T 29-03-2018 IPR010290 Transmembrane secretion effector CSW12_RS13200 0959970574a497b48d220196f61d0e83 400 SUPERFAMILY SSF103473 3 391 6.93E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS23885 378b7ce04cc42d7089b72bdec32658a1 212 Pfam PF13630 SdpI/YhfL protein family 134 202 2.0E-21 T 29-03-2018 IPR025962 SdpI/YhfL protein family CSW12_RS23885 378b7ce04cc42d7089b72bdec32658a1 212 PIRSF PIRSF038959 1 211 5.2E-53 T 29-03-2018 IPR026272 Immunity protein SdpI CSW12_RS23885 378b7ce04cc42d7089b72bdec32658a1 212 Pfam PF07853 Protein of unknown function (DUF1648) 9 51 4.0E-14 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CSW12_RS11305 b81beced6bce8c05c41a1967a962d8ca 93 Pfam PF06949 Protein of unknown function (DUF1292) 17 88 5.2E-12 T 29-03-2018 IPR009711 Uncharacterised protein family UPF0473 CSW12_RS03930 297ec4cd3190dabca68a59cac6bdfeb4 112 Pfam PF09685 Domain of unknown function (DUF4870) 14 101 4.6E-9 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 CSW12_RS17545 58d9b58f3b9ebd9bea46589485807e43 491 Pfam PF01425 Amidase 31 471 4.1E-78 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS17545 58d9b58f3b9ebd9bea46589485807e43 491 SUPERFAMILY SSF75304 12 488 4.45E-103 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS17545 58d9b58f3b9ebd9bea46589485807e43 491 Gene3D G3DSA:3.90.1300.10 9 491 1.4E-116 T 29-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CSW12_RS17955 7bde513b4a2b07fd55f07310bac2e944 602 Pfam PF06276 Ferric iron reductase FhuF-like transporter 419 578 4.2E-39 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain CSW12_RS17955 7bde513b4a2b07fd55f07310bac2e944 602 Pfam PF04183 IucA / IucC family 153 387 4.2E-54 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CSW12_RS11270 e4cd1b3e1798bcf1571350fc52e8c8d8 552 Pfam PF16949 Putative ATP-binding cassette 68 448 7.0E-14 T 29-03-2018 IPR031599 Putative ATP-binding cassette CSW12_RS23435 130577c6b78a5282866150166dbd4147 87 Gene3D G3DSA:1.10.287.620 1 84 2.7E-4 T 29-03-2018 CSW12_RS23435 130577c6b78a5282866150166dbd4147 87 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 6.3E-35 T 29-03-2018 IPR019668 Uncharacterised protein family YtzC CSW12_RS19395 fb0cfa1b39cf2e3767c10ee7d6a39004 154 SUPERFAMILY SSF158397 36 153 8.5E-26 T 29-03-2018 CSW12_RS19395 fb0cfa1b39cf2e3767c10ee7d6a39004 154 Gene3D G3DSA:1.20.120.490 32 153 4.0E-25 T 29-03-2018 IPR024042 Hypothetical protein TM1646-like domain CSW12_RS19395 fb0cfa1b39cf2e3767c10ee7d6a39004 154 Pfam PF03885 Protein of unknown function (DUF327) 26 153 1.3E-24 T 29-03-2018 IPR005585 Protein of unknown function DUF327 CSW12_RS29855 4ff91a543cfce29bf2c1c619bfa2bda5 75 ProDom PD275078 PLASMID PXO2-72/BXB0098/GBAA_PXO2_0098 6 60 2.0E-5 T 29-03-2018 IPR020250 Uncharacterised protein family, plasmid pXO2-72 CSW12_RS29855 4ff91a543cfce29bf2c1c619bfa2bda5 75 Pfam PF17443 Uncharacterized protein pXO2-72 5 58 3.2E-11 T 29-03-2018 IPR020250 Uncharacterised protein family, plasmid pXO2-72 CSW12_RS13120 95c0e04e773812349c3aa9361730c03e 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 2.4E-25 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13120 95c0e04e773812349c3aa9361730c03e 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 2.0E-21 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS04915 70c9f4a7583e135c586a8fb2df0a906a 425 Gene3D G3DSA:3.20.20.60 1 406 1.4E-150 T 29-03-2018 CSW12_RS04915 70c9f4a7583e135c586a8fb2df0a906a 425 ProSitePatterns PS00161 Isocitrate lyase signature. 184 189 - T 29-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CSW12_RS04915 70c9f4a7583e135c586a8fb2df0a906a 425 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 6 248 2.3E-108 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CSW12_RS04915 70c9f4a7583e135c586a8fb2df0a906a 425 PIRSF PIRSF001362 1 425 7.1E-241 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CSW12_RS04915 70c9f4a7583e135c586a8fb2df0a906a 425 Pfam PF00463 Isocitrate lyase family 11 250 7.5E-57 T 29-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CSW12_RS04915 70c9f4a7583e135c586a8fb2df0a906a 425 SUPERFAMILY SSF51621 5 423 1.93E-156 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS20815 9abf939412e27921e18a792372c093b9 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 310 324 2.3E-6 T 29-03-2018 IPR003004 GspF/PilC family CSW12_RS20815 9abf939412e27921e18a792372c093b9 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 108 136 2.3E-6 T 29-03-2018 IPR003004 GspF/PilC family CSW12_RS20815 9abf939412e27921e18a792372c093b9 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 326 345 2.3E-6 T 29-03-2018 IPR003004 GspF/PilC family CSW12_RS20815 9abf939412e27921e18a792372c093b9 345 PRINTS PR00812 Bacterial general secretion pathway protein F signature 12 24 2.3E-6 T 29-03-2018 IPR003004 GspF/PilC family CSW12_RS20815 9abf939412e27921e18a792372c093b9 345 Pfam PF00482 Type II secretion system (T2SS), protein F 215 337 7.8E-19 T 29-03-2018 IPR018076 Type II secretion system F domain CSW12_RS20815 9abf939412e27921e18a792372c093b9 345 Pfam PF00482 Type II secretion system (T2SS), protein F 17 136 1.3E-14 T 29-03-2018 IPR018076 Type II secretion system F domain CSW12_RS08965 e1e4481694ab2abdcfd68475e34be4fe 445 Gene3D G3DSA:3.50.50.60 1 444 4.5E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS08965 e1e4481694ab2abdcfd68475e34be4fe 445 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 34 1.1E-4 T 29-03-2018 CSW12_RS08965 e1e4481694ab2abdcfd68475e34be4fe 445 PIRSF PIRSF038984 122 443 2.7E-12 T 29-03-2018 IPR028348 FAD dependent protein CSW12_RS08965 e1e4481694ab2abdcfd68475e34be4fe 445 PIRSF PIRSF038984 2 100 0.0055 T 29-03-2018 IPR028348 FAD dependent protein CSW12_RS08965 e1e4481694ab2abdcfd68475e34be4fe 445 SUPERFAMILY SSF51905 1 222 1.05E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS08965 e1e4481694ab2abdcfd68475e34be4fe 445 SUPERFAMILY SSF51905 386 442 1.05E-24 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS08160 eb7e7d1be14ea03a1d272d0cd7cf660a 538 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 10 536 4.5E-199 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CSW12_RS08160 eb7e7d1be14ea03a1d272d0cd7cf660a 538 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 538 31.786 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CSW12_RS08160 eb7e7d1be14ea03a1d272d0cd7cf660a 538 PIRSF PIRSF012535 1 538 6.6E-232 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CSW12_RS08160 eb7e7d1be14ea03a1d272d0cd7cf660a 538 Pfam PF10079 Bacillithiol biosynthesis BshC 1 535 1.6E-177 T 29-03-2018 IPR011199 Bacillithiol biosynthesis BshC CSW12_RS29460 abf0e75f3d7f0481768890ab824176f9 228 SUPERFAMILY SSF53098 70 190 7.78E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS29460 abf0e75f3d7f0481768890ab824176f9 228 Pfam PF13610 DDE domain 71 206 3.8E-43 T 29-03-2018 IPR032874 DDE domain CSW12_RS29460 abf0e75f3d7f0481768890ab824176f9 228 Gene3D G3DSA:3.30.420.10 61 214 1.7E-15 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS14320 f70db7a3309ef0a4ff77cdfa602916e9 304 Pfam PF00892 EamA-like transporter family 16 142 6.4E-28 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS14320 f70db7a3309ef0a4ff77cdfa602916e9 304 Pfam PF00892 EamA-like transporter family 152 284 5.8E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS14320 f70db7a3309ef0a4ff77cdfa602916e9 304 SUPERFAMILY SSF103481 188 287 5.89E-12 T 29-03-2018 CSW12_RS14320 f70db7a3309ef0a4ff77cdfa602916e9 304 SUPERFAMILY SSF103481 43 144 1.44E-17 T 29-03-2018 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 SUPERFAMILY SSF47323 645 878 3.55E-49 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 Gene3D G3DSA:1.10.730.10 566 912 6.9E-62 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 29-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 SUPERFAMILY SSF52374 384 637 3.38E-136 T 29-03-2018 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 SUPERFAMILY SSF52374 12 197 3.38E-136 T 29-03-2018 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 Pfam PF08264 Anticodon-binding domain of tRNA 675 817 4.4E-30 T 29-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 SUPERFAMILY SSF50677 200 384 5.34E-52 T 29-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 623 2.6E-191 T 29-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 Gene3D G3DSA:3.90.740.10 215 481 2.9E-92 T 29-03-2018 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 382 397 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 558 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 220 243 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 509 522 3.0E-30 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 830 2.3E-291 T 29-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1026 13.921 T 29-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 SUPERFAMILY SSF47323 946 1014 8.5E-6 T 29-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CSW12_RS17070 13912c3d62be8b5238a69364ee65c50c 1033 Gene3D G3DSA:3.40.50.620 26 214 3.1E-40 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS04105 c29da4cf87af0e4ce7646d91f63f18da 36 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 12 35 4.1E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS04105 c29da4cf87af0e4ce7646d91f63f18da 36 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 11 33 1.6E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS14595 54b55ac2965d67d586e1fdd854c8f663 210 SUPERFAMILY SSF51161 15 204 4.99E-48 T 29-03-2018 IPR011004 Trimeric LpxA-like CSW12_RS14595 54b55ac2965d67d586e1fdd854c8f663 210 Gene3D G3DSA:2.160.10.10 6 206 2.3E-44 T 29-03-2018 CSW12_RS14595 54b55ac2965d67d586e1fdd854c8f663 210 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 122 150 - T 29-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CSW12_RS14595 54b55ac2965d67d586e1fdd854c8f663 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 148 3.7E-11 T 29-03-2018 IPR001451 Hexapeptide repeat CSW12_RS01800 cb564676f8260a78e776bf094a03baca 273 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS01800 cb564676f8260a78e776bf094a03baca 273 Gene3D G3DSA:3.40.50.300 2 246 1.7E-62 T 29-03-2018 CSW12_RS01800 cb564676f8260a78e776bf094a03baca 273 SMART SM00382 29 249 5.8E-15 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS01800 cb564676f8260a78e776bf094a03baca 273 SUPERFAMILY SSF52540 4 232 2.88E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS01800 cb564676f8260a78e776bf094a03baca 273 Pfam PF00005 ABC transporter 21 168 9.6E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 29-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 Pfam PF01026 TatD related DNase 3 252 2.0E-87 T 29-03-2018 IPR001130 TatD family GO:0016788 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 Gene3D G3DSA:3.20.20.140 1 255 5.2E-96 T 29-03-2018 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 PIRSF PIRSF005902 1 255 2.9E-90 T 29-03-2018 IPR001130 TatD family GO:0016788 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 1.2E-100 T 29-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CSW12_RS27540 671fe8ae2730b0e5a79783c56f649148 255 SUPERFAMILY SSF51556 1 254 1.25E-97 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS19150 9619daac79f6f0600e9fa52f287f67e0 422 SUPERFAMILY SSF103473 18 409 2.62E-44 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS19150 9619daac79f6f0600e9fa52f287f67e0 422 Gene3D G3DSA:1.20.1250.20 9 213 3.3E-21 T 29-03-2018 CSW12_RS19150 9619daac79f6f0600e9fa52f287f67e0 422 Gene3D G3DSA:1.20.1250.20 219 410 3.7E-12 T 29-03-2018 CSW12_RS19150 9619daac79f6f0600e9fa52f287f67e0 422 Pfam PF07690 Major Facilitator Superfamily 24 377 4.8E-25 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS15995 e94cb547ad9e8789447e99ac404bb74b 216 Pfam PF00302 Chloramphenicol acetyltransferase 3 205 7.4E-85 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CSW12_RS15995 e94cb547ad9e8789447e99ac404bb74b 216 Gene3D G3DSA:3.30.559.10 1 210 9.1E-37 T 29-03-2018 CSW12_RS15995 e94cb547ad9e8789447e99ac404bb74b 216 PIRSF PIRSF000440 1 214 3.5E-85 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CSW12_RS15995 e94cb547ad9e8789447e99ac404bb74b 216 SMART SM01059 1 205 4.7E-109 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CSW12_RS15995 e94cb547ad9e8789447e99ac404bb74b 216 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 9 199 4.0E-104 T 29-03-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 CSW12_RS15995 e94cb547ad9e8789447e99ac404bb74b 216 SUPERFAMILY SSF52777 1 211 3.08E-73 T 29-03-2018 CSW12_RS18040 b22e1fd08a17a0fd169586514ca25cd2 275 Gene3D G3DSA:3.20.20.370 50 275 3.1E-57 T 29-03-2018 CSW12_RS18040 b22e1fd08a17a0fd169586514ca25cd2 275 SUPERFAMILY SSF88713 41 268 9.34E-68 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS18040 b22e1fd08a17a0fd169586514ca25cd2 275 Pfam PF01522 Polysaccharide deacetylase 79 196 3.1E-34 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS13680 07d72b2e5f9b304253524493adcffc04 128 Pfam PF10990 Protein of unknown function (DUF2809) 32 115 5.9E-30 T 29-03-2018 IPR021257 Protein of unknown function DUF2809 CSW12_RS01275 730800585cd9d93f76bbe0796ec02a04 134 Gene3D G3DSA:1.10.287.70 10 132 1.8E-12 T 29-03-2018 CSW12_RS01275 730800585cd9d93f76bbe0796ec02a04 134 Pfam PF07885 Ion channel 44 126 3.8E-11 T 29-03-2018 IPR013099 Potassium channel domain CSW12_RS01275 730800585cd9d93f76bbe0796ec02a04 134 SUPERFAMILY SSF81324 25 123 7.2E-12 T 29-03-2018 CSW12_RS18745 89bc98f4f1ca52b4db48e82f7204cd4c 541 Pfam PF14158 YndJ-like protein 28 279 8.7E-86 T 29-03-2018 IPR025450 YndJ-like protein CSW12_RS17745 5015480fadbad5a1a33c4dfdc279d8e5 156 Pfam PF00583 Acetyltransferase (GNAT) family 38 129 2.9E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17745 5015480fadbad5a1a33c4dfdc279d8e5 156 Gene3D G3DSA:3.40.630.30 32 152 1.8E-18 T 29-03-2018 CSW12_RS17745 5015480fadbad5a1a33c4dfdc279d8e5 156 SUPERFAMILY SSF55729 1 142 1.26E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17745 5015480fadbad5a1a33c4dfdc279d8e5 156 Gene3D G3DSA:1.10.287.900 2 31 7.0E-16 T 29-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CSW12_RS12500 93de43b2efa8e2c7719883786c79d63e 251 Pfam PF02517 CAAX protease self-immunity 110 211 1.4E-13 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS21735 bb6c2619323fa150f81c73c1fc24683c 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 1.4E-23 T 29-03-2018 IPR021320 Protein of unknown function DUF2905 CSW12_RS03395 55640d884117038e87866cb1b8d0c0fa 93 Pfam PF06803 Protein of unknown function (DUF1232) 37 71 1.9E-11 T 29-03-2018 IPR010652 Protein of unknown function DUF1232 CSW12_RS03395 55640d884117038e87866cb1b8d0c0fa 93 PIRSF PIRSF029962 1 93 1.3E-47 T 29-03-2018 IPR016941 Uncharacterised conserved protein UCP029962 CSW12_RS25185 fe029756a2b342607f53d7b78437c848 144 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 13 131 19.401 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CSW12_RS25185 fe029756a2b342607f53d7b78437c848 144 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 15 125 6.3E-24 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CSW12_RS25185 fe029756a2b342607f53d7b78437c848 144 TIGRFAM TIGR00494 crcB: protein CrcB 15 129 3.6E-27 T 29-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 Pfam PF02254 TrkA-N domain 118 238 3.3E-13 T 29-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 SUPERFAMILY SSF116726 296 329 6.8E-5 T 29-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 SUPERFAMILY SSF81324 14 135 2.35E-24 T 29-03-2018 CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 Gene3D G3DSA:3.40.50.720 106 239 2.6E-21 T 29-03-2018 CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 Gene3D G3DSA:1.20.5.110 63 99 1.3E-5 T 29-03-2018 CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 Pfam PF07885 Ion channel 23 97 9.2E-14 T 29-03-2018 IPR013099 Potassium channel domain CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 SUPERFAMILY SSF51735 115 251 7.19E-17 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS24265 8a991600f2745e413d55060d6c86c065 331 Gene3D G3DSA:1.10.287.70 10 61 2.6E-8 T 29-03-2018 CSW12_RS20690 edadcbf7d843fa25ef41af1f432ca01a 210 Pfam PF13346 ABC-2 family transporter protein 3 206 8.5E-38 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CSW12_RS29980 022abe2f87cff89eb7334a0ac6de45a9 482 ProSitePatterns PS00640 Eukaryotic thiol (cysteine) proteases asparagine active site. 260 279 - T 29-03-2018 IPR025661 Cysteine peptidase, asparagine active site CSW12_RS29980 022abe2f87cff89eb7334a0ac6de45a9 482 SUPERFAMILY SSF54001 67 290 1.44E-66 T 29-03-2018 CSW12_RS29980 022abe2f87cff89eb7334a0ac6de45a9 482 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 245 255 - T 29-03-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 CSW12_RS29980 022abe2f87cff89eb7334a0ac6de45a9 482 Gene3D G3DSA:3.90.70.10 3 305 1.8E-68 T 29-03-2018 CSW12_RS29980 022abe2f87cff89eb7334a0ac6de45a9 482 Pfam PF00112 Papain family cysteine protease 77 288 2.4E-52 T 29-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CSW12_RS29980 022abe2f87cff89eb7334a0ac6de45a9 482 SMART SM00645 76 294 8.5E-56 T 29-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CSW12_RS22330 3f87494278be1b90a41f33c2cdd76858 327 Pfam PF01032 FecCD transport family 14 320 9.4E-87 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS22330 3f87494278be1b90a41f33c2cdd76858 327 SUPERFAMILY SSF81345 3 320 1.83E-75 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS22330 3f87494278be1b90a41f33c2cdd76858 327 Gene3D G3DSA:1.10.3470.10 1 326 7.1E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS16615 f7bd6b50b25b1e2671812c81c6141d16 452 PIRSF PIRSF002746 2 452 7.4E-158 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS16615 f7bd6b50b25b1e2671812c81c6141d16 452 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 8 451 7.5E-156 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS16615 f7bd6b50b25b1e2671812c81c6141d16 452 Pfam PF02447 GntP family permease 5 449 7.3E-167 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 29-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 37.406 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 SUPERFAMILY SSF52317 2 189 3.7E-53 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 PIRSF PIRSF005639 1 191 2.6E-74 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 185 5.7E-91 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 Gene3D G3DSA:3.40.50.880 1 196 1.5E-48 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS27385 431fe387f5d1e8ccb560040929f16653 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 2.7E-72 T 29-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 SMART SM00855 3 189 1.0E-26 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 4.6E-29 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 233 1.9E-108 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 PIRSF PIRSF000709 3 116 6.8E-7 T 29-03-2018 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 PIRSF PIRSF000709 172 232 0.52 T 29-03-2018 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.081 T 29-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 SUPERFAMILY SSF53254 1 230 6.06E-74 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 Gene3D G3DSA:3.40.50.1240 1 239 5.7E-60 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS15660 a4800eafeb9ab2c1697e64327c14adeb 245 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 29-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CSW12_RS06330 fad63867efd7e55f767081fbbef78961 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 7.5E-17 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS06330 fad63867efd7e55f767081fbbef78961 126 Gene3D G3DSA:1.10.287.100 78 116 3.3E-4 T 29-03-2018 CSW12_RS06330 fad63867efd7e55f767081fbbef78961 126 SUPERFAMILY SSF46785 4 87 1.42E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06330 fad63867efd7e55f767081fbbef78961 126 Gene3D G3DSA:1.10.10.10 1 76 3.4E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS06330 fad63867efd7e55f767081fbbef78961 126 SMART SM00345 15 74 7.6E-19 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS17275 21e73ee91888c5878bc7c88518f0c61e 229 Pfam PF02665 Nitrate reductase gamma subunit 3 222 1.6E-87 T 29-03-2018 IPR023234 NarG-like domain CSW12_RS17275 21e73ee91888c5878bc7c88518f0c61e 229 Gene3D G3DSA:1.20.950.20 1 214 3.2E-47 T 29-03-2018 CSW12_RS17275 21e73ee91888c5878bc7c88518f0c61e 229 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 222 5.0E-85 T 29-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CSW12_RS17275 21e73ee91888c5878bc7c88518f0c61e 229 SUPERFAMILY SSF103501 1 222 1.83E-69 T 29-03-2018 IPR023234 NarG-like domain CSW12_RS23500 ddbaf6fb09c8b31fe1a1684d70be91df 200 Gene3D G3DSA:3.90.550.10 1 200 3.4E-29 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS23500 ddbaf6fb09c8b31fe1a1684d70be91df 200 SUPERFAMILY SSF53448 1 193 4.43E-30 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS23500 ddbaf6fb09c8b31fe1a1684d70be91df 200 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 2 193 23.165 T 29-03-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CSW12_RS23500 ddbaf6fb09c8b31fe1a1684d70be91df 200 Pfam PF12804 MobA-like NTP transferase domain 6 154 3.2E-30 T 29-03-2018 IPR025877 MobA-like NTP transferase CSW12_RS13730 150a8513949e4f8af961b0bda6e415da 285 SUPERFAMILY SSF53850 26 284 4.98E-82 T 29-03-2018 CSW12_RS13730 150a8513949e4f8af961b0bda6e415da 285 Gene3D G3DSA:3.40.190.10 23 127 2.3E-17 T 29-03-2018 CSW12_RS13730 150a8513949e4f8af961b0bda6e415da 285 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 274 3.1E-69 T 29-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CSW12_RS13730 150a8513949e4f8af961b0bda6e415da 285 Gene3D G3DSA:3.40.190.100 128 235 4.6E-39 T 29-03-2018 CSW12_RS15550 a5c65256c1ddb218148eac02f4f188cd 382 Pfam PF01757 Acyltransferase family 19 359 8.4E-36 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 PRINTS PR01607 Apyrase family signature 36 54 9.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 PRINTS PR01607 Apyrase family signature 394 417 9.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 PRINTS PR01607 Apyrase family signature 251 274 9.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 PRINTS PR01607 Apyrase family signature 222 239 9.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 PRINTS PR01607 Apyrase family signature 465 484 9.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 PRINTS PR01607 Apyrase family signature 277 297 9.3E-25 T 29-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 Gene3D G3DSA:3.60.21.10 32 341 7.9E-75 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 Pfam PF02872 5'-nucleotidase, C-terminal domain 342 490 2.9E-46 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 SUPERFAMILY SSF55816 339 528 7.85E-55 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 Pfam PF00149 Calcineurin-like phosphoesterase 41 269 9.9E-11 T 29-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 SUPERFAMILY SSF56300 33 341 2.59E-77 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 Gene3D G3DSA:3.90.780.10 342 528 5.8E-59 T 29-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS12160 ab22acc1981fd4776adb6e3511d7c177 529 ProSitePatterns PS00786 5'-nucleotidase signature 2. 114 125 - T 29-03-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CSW12_RS05350 31cbacc925d71388e93a15d723d6aa2e 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 234 288 3.4E-19 T 29-03-2018 IPR019264 Domain of unknown function DUF2179 CSW12_RS05350 31cbacc925d71388e93a15d723d6aa2e 293 PIRSF PIRSF006483 5 293 3.6E-94 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS05350 31cbacc925d71388e93a15d723d6aa2e 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 22 228 6.5E-58 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS02525 112dab32520518cd90166c92e0cc8231 227 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 11 123 3.6E-6 T 29-03-2018 IPR006520 Streptococcus phage 7201, Orf34, N-terminal CSW12_RS02525 112dab32520518cd90166c92e0cc8231 227 Pfam PF05709 Phage tail protein 27 226 3.2E-9 T 29-03-2018 IPR008841 Siphovirus-type tail component CSW12_RS07815 09b20e15f87958a275aae98b5636314b 63 Pfam PF14156 Antirepressor AbbA 1 61 1.8E-29 T 29-03-2018 IPR025446 Antirepressor AbbA CSW12_RS07815 09b20e15f87958a275aae98b5636314b 63 ProDom PD054279 YKZF 7 58 3.0E-8 T 29-03-2018 CSW12_RS22475 4de5c6eacd94e12aa681e97e79e56a1f 163 Pfam PF08761 dUTPase 2 163 9.7E-53 T 29-03-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 CSW12_RS22475 4de5c6eacd94e12aa681e97e79e56a1f 163 SUPERFAMILY SSF101386 1 163 8.94E-49 T 29-03-2018 CSW12_RS22475 4de5c6eacd94e12aa681e97e79e56a1f 163 Gene3D G3DSA:1.10.4010.10 1 163 4.4E-48 T 29-03-2018 CSW12_RS22475 4de5c6eacd94e12aa681e97e79e56a1f 163 PIRSF PIRSF030140 1 163 1.5E-59 T 29-03-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 CSW12_RS12870 a5ff8f14445a464794a9522fb1128c90 101 Pfam PF14118 YfzA-like protein 8 97 1.7E-41 T 29-03-2018 IPR025627 YfzA-like protein CSW12_RS10480 c034070aec0fad9fdf1e48135dee1ecb 595 SUPERFAMILY SSF55486 6 579 5.59E-116 T 29-03-2018 CSW12_RS10480 c034070aec0fad9fdf1e48135dee1ecb 595 Pfam PF08439 Oligopeptidase F 114 182 5.5E-18 T 29-03-2018 IPR013647 Oligopeptidase F, N-terminal domain CSW12_RS10480 c034070aec0fad9fdf1e48135dee1ecb 595 Pfam PF01432 Peptidase family M3 203 582 7.6E-68 T 29-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CSW12_RS10480 c034070aec0fad9fdf1e48135dee1ecb 595 Gene3D G3DSA:1.10.1370.10 39 585 1.1E-50 T 29-03-2018 CSW12_RS10480 c034070aec0fad9fdf1e48135dee1ecb 595 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 10 593 5.6E-182 T 29-03-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 CSW12_RS20500 5f8bc65e61b5067f695fa56a99366525 130 Pfam PF03780 Asp23 family, cell envelope-related function 14 118 6.1E-36 T 29-03-2018 IPR005531 Alkaline shock protein Asp23 CSW12_RS18670 dd3a5ebc338078c3c074338b67aa64a4 234 Pfam PF01522 Polysaccharide deacetylase 42 147 4.0E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS18670 dd3a5ebc338078c3c074338b67aa64a4 234 Gene3D G3DSA:3.20.20.370 25 234 2.5E-45 T 29-03-2018 CSW12_RS18670 dd3a5ebc338078c3c074338b67aa64a4 234 SUPERFAMILY SSF88713 7 229 2.15E-50 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS13125 c3bd8594832589649e971a5c3aa87c45 47 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 44 7.8E-17 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13125 c3bd8594832589649e971a5c3aa87c45 47 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 3.8E-20 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS05670 dee7105e08618e5d1df02959b648b8d5 140 SUPERFAMILY SSF55729 4 140 3.09E-37 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS05670 dee7105e08618e5d1df02959b648b8d5 140 Pfam PF13673 Acetyltransferase (GNAT) domain 21 140 1.2E-21 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS05670 dee7105e08618e5d1df02959b648b8d5 140 Gene3D G3DSA:3.40.630.30 2 140 3.0E-35 T 29-03-2018 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 Gene3D G3DSA:3.10.20.10 28 84 1.1E-18 T 29-03-2018 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 262 31.133 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 PIRSF PIRSF015626 2 265 2.5E-75 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 261 4.7E-71 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 Pfam PF02634 FdhD/NarQ family 26 261 4.6E-78 T 29-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 Gene3D G3DSA:3.40.140.10 128 266 4.7E-48 T 29-03-2018 CSW12_RS01655 433626dd2a501b5a47037fc74670c47a 268 SUPERFAMILY SSF53927 6 261 1.83E-75 T 29-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CSW12_RS05465 56c9ffcabb45f763f513f98a94d231e4 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 421 1.4E-65 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS05465 56c9ffcabb45f763f513f98a94d231e4 464 Pfam PF01554 MatE 247 407 7.2E-29 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS05465 56c9ffcabb45f763f513f98a94d231e4 464 Pfam PF01554 MatE 22 182 3.4E-26 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS05465 56c9ffcabb45f763f513f98a94d231e4 464 PIRSF PIRSF006603 1 457 5.2E-86 T 29-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CSW12_RS17460 68c26cbcd94bd3a67b653eccb3ae0798 140 Gene3D G3DSA:3.40.630.30 5 140 6.6E-16 T 29-03-2018 CSW12_RS17460 68c26cbcd94bd3a67b653eccb3ae0798 140 SUPERFAMILY SSF55729 7 134 1.33E-18 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17460 68c26cbcd94bd3a67b653eccb3ae0798 140 Pfam PF00583 Acetyltransferase (GNAT) family 35 129 2.4E-13 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS30020 c4b8fbeb567345613bd716bf0d8e4f8c 532 SUPERFAMILY SSF53474 59 266 2.99E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS30020 c4b8fbeb567345613bd716bf0d8e4f8c 532 Gene3D G3DSA:3.40.50.1820 190 507 2.7E-9 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS30020 c4b8fbeb567345613bd716bf0d8e4f8c 532 Gene3D G3DSA:3.40.50.1820 53 189 8.1E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS23935 dcaa328e9bd68941dba3afff02b74c1b 63 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 19 40 1.1E-9 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS23935 dcaa328e9bd68941dba3afff02b74c1b 63 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 19 38 6.3E-10 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS21755 879a9648cc6afc9e73fd53ce1bd2f22a 176 Pfam PF08955 BofC C-terminal domain 91 163 2.3E-24 T 29-03-2018 IPR015050 Bypass of forespore C, C-terminal CSW12_RS21755 879a9648cc6afc9e73fd53ce1bd2f22a 176 Pfam PF08977 Bypass of Forespore C, N terminal 39 89 2.9E-21 T 29-03-2018 IPR015071 Bypass-of-forespore C, N-terminal CSW12_RS06795 f7c7d7d3682e10a1da66fc3b769cd187 451 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 419 1.0E-142 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS06795 f7c7d7d3682e10a1da66fc3b769cd187 451 Pfam PF05525 Branched-chain amino acid transport protein 6 432 8.8E-158 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS00295 4f459ced2a3c0f63b037168cd521be3b 193 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 11 152 1.8E-21 T 29-03-2018 IPR006433 Prohead protease CSW12_RS00295 4f459ced2a3c0f63b037168cd521be3b 193 Pfam PF04586 Caudovirus prohead serine protease 8 156 1.1E-45 T 29-03-2018 IPR006433 Prohead protease CSW12_RS00295 4f459ced2a3c0f63b037168cd521be3b 193 Gene3D G3DSA:3.20.16.10 6 192 3.7E-29 T 29-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CSW12_RS24450 c44cb533210f9bc54203c9c01673b842 117 Pfam PF06486 Protein of unknown function (DUF1093) 24 104 2.6E-27 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS24450 c44cb533210f9bc54203c9c01673b842 117 SUPERFAMILY SSF159121 24 115 1.57E-31 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS24450 c44cb533210f9bc54203c9c01673b842 117 TIGRFAM TIGR01655 yxeA_fam: conserved hypothetical protein 4 114 5.4E-24 T 29-03-2018 IPR006542 Protein of unknown function DUF1093 CSW12_RS04400 d0740a8bab8d143cd9a3a24406c9473b 110 Pfam PF08921 Domain of unknown function (DUF1904) 1 107 1.6E-31 T 29-03-2018 IPR015017 Protein of unknown function DUF1904 CSW12_RS04400 d0740a8bab8d143cd9a3a24406c9473b 110 SUPERFAMILY SSF55331 1 108 8.55E-36 T 29-03-2018 IPR014347 Tautomerase/MIF superfamily CSW12_RS04400 d0740a8bab8d143cd9a3a24406c9473b 110 Gene3D G3DSA:3.30.429.10 2 107 5.9E-38 T 29-03-2018 CSW12_RS23275 0f2b080337958ad92f442c78b7563a73 285 Pfam PF06800 Sugar transport protein 5 282 9.5E-110 T 29-03-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 CSW12_RS23275 0f2b080337958ad92f442c78b7563a73 285 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 1 284 7.2E-115 T 29-03-2018 CSW12_RS23275 0f2b080337958ad92f442c78b7563a73 285 SUPERFAMILY SSF103481 36 137 1.2E-10 T 29-03-2018 CSW12_RS23275 0f2b080337958ad92f442c78b7563a73 285 SUPERFAMILY SSF103481 189 271 6.8E-7 T 29-03-2018 CSW12_RS15235 19f33d51fbee92ddfc7e8e7a2a01e207 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 40 54 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS15235 19f33d51fbee92ddfc7e8e7a2a01e207 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 22 31 - T 29-03-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 CSW12_RS15235 19f33d51fbee92ddfc7e8e7a2a01e207 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 7 61 2.8E-22 T 29-03-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 CSW12_RS12645 e1da3f09d1b598f864583bebaedaa4f1 180 Pfam PF13302 Acetyltransferase (GNAT) domain 10 150 8.3E-34 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS12645 e1da3f09d1b598f864583bebaedaa4f1 180 SUPERFAMILY SSF55729 3 175 5.59E-55 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS12645 e1da3f09d1b598f864583bebaedaa4f1 180 Gene3D G3DSA:3.40.630.30 3 180 7.3E-33 T 29-03-2018 CSW12_RS10085 28823b10836bfae738dde6b6a83a4252 133 Gene3D G3DSA:1.20.5.1070 47 131 1.5E-8 T 29-03-2018 CSW12_RS30140 bd4d955e14d1c6255e2887c2f1efa227 305 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 10 301 6.9E-66 T 29-03-2018 IPR010106 Recombination-promoting nuclease RpnA CSW12_RS30140 bd4d955e14d1c6255e2887c2f1efa227 305 Pfam PF12784 PD-(D/E)XK nuclease family transposase 9 245 8.3E-62 T 29-03-2018 CSW12_RS30140 bd4d955e14d1c6255e2887c2f1efa227 305 Gene3D G3DSA:1.10.10.60 244 305 8.0E-12 T 29-03-2018 CSW12_RS21050 1ede4bee8478694aa3f920017465beb7 316 Pfam PF02401 LytB protein 4 284 3.7E-81 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CSW12_RS21050 1ede4bee8478694aa3f920017465beb7 316 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 31.968 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CSW12_RS21050 1ede4bee8478694aa3f920017465beb7 316 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 286 9.8E-92 T 29-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 Gene3D G3DSA:3.40.1830.10 3 179 8.8E-56 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 362 384 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 155 177 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 244 263 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 300 320 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 388 407 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 14 31 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 79 98 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 323 344 2.3E-63 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 SUPERFAMILY SSF144052 3 408 1.96E-135 T 29-03-2018 CSW12_RS18415 1a92cdc69dea7e57645a9b4863e48027 409 Pfam PF02073 Thermophilic metalloprotease (M29) 4 407 1.5E-159 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS08140 8431b572312c978c55455569a8c344b7 168 Gene3D G3DSA:1.10.10.60 7 124 3.0E-8 T 29-03-2018 CSW12_RS08140 8431b572312c978c55455569a8c344b7 168 Pfam PF13921 Myb-like DNA-binding domain 9 62 2.3E-6 T 29-03-2018 CSW12_RS08140 8431b572312c978c55455569a8c344b7 168 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 155 1.2E-56 T 29-03-2018 IPR014243 Transcription factor, RsfA CSW12_RS08140 8431b572312c978c55455569a8c344b7 168 SUPERFAMILY SSF46689 6 62 5.62E-6 T 29-03-2018 IPR009057 Homeobox domain-like GO:0003677 CSW12_RS08140 8431b572312c978c55455569a8c344b7 168 SMART SM00717 5 59 0.0037 T 29-03-2018 IPR001005 SANT/Myb domain CSW12_RS20310 769cafdaf722b04da6d7dc5a7d0ce613 79 Pfam PF13033 Protein of unknown function (DUF3894) 24 77 3.5E-37 T 29-03-2018 IPR024993 Protein of unknown function DUF3894 CSW12_RS01825 41445ed1f46642c314497524780ed77d 627 Pfam PF00092 von Willebrand factor type A domain 436 601 9.5E-6 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS01825 41445ed1f46642c314497524780ed77d 627 Gene3D G3DSA:3.40.50.410 427 626 1.1E-13 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS01825 41445ed1f46642c314497524780ed77d 627 SMART SM00327 431 622 1.0E-9 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS01825 41445ed1f46642c314497524780ed77d 627 SUPERFAMILY SSF53300 435 621 3.27E-15 T 29-03-2018 IPR002035 von Willebrand factor, type A CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 Gene3D G3DSA:3.40.50.1000 183 298 6.1E-25 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 ProSitePatterns PS01228 Hypothetical cof family signature 1. 13 24 - T 29-03-2018 CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 Pfam PF08282 haloacid dehalogenase-like hydrolase 14 288 1.5E-66 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 13 261 1.8E-27 T 29-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 13 288 3.7E-58 T 29-03-2018 IPR000150 Cof family GO:0016787 CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 ProSitePatterns PS01229 Hypothetical cof family signature 2. 242 264 - T 29-03-2018 CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 Gene3D G3DSA:3.40.50.1000 11 129 5.5E-15 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS28605 ebd7de2223e66f98e29b13543d2724f8 300 SUPERFAMILY SSF56784 12 294 2.04E-69 T 29-03-2018 IPR023214 HAD-like domain CSW12_RS14800 95a00b36d16ce0505cbb0faa56f8a5b8 285 SUPERFAMILY SSF51735 1 283 1.19E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS14800 95a00b36d16ce0505cbb0faa56f8a5b8 285 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 1.2E-19 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS14800 95a00b36d16ce0505cbb0faa56f8a5b8 285 Gene3D G3DSA:3.40.50.720 1 285 8.8E-34 T 29-03-2018 CSW12_RS23830 4a85d202138b6f2a01970780f53ee4c3 169 Pfam PF09965 Uncharacterized protein conserved in bacteria (DUF2199) 18 153 8.4E-47 T 29-03-2018 IPR018697 Protein of unknown function DUF2199 CSW12_RS01925 1744426083c84b241700f301105fb6eb 144 PRINTS PR00332 Histidine triad family signature 90 100 3.3E-7 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS01925 1744426083c84b241700f301105fb6eb 144 PRINTS PR00332 Histidine triad family signature 25 43 3.3E-7 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS01925 1744426083c84b241700f301105fb6eb 144 PRINTS PR00332 Histidine triad family signature 4 20 3.3E-7 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS01925 1744426083c84b241700f301105fb6eb 144 Pfam PF01230 HIT domain 12 104 6.0E-19 T 29-03-2018 IPR001310 Histidine triad (HIT) protein CSW12_RS01925 1744426083c84b241700f301105fb6eb 144 SUPERFAMILY SSF54197 2 126 1.41E-33 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS01925 1744426083c84b241700f301105fb6eb 144 Gene3D G3DSA:3.30.428.10 1 142 1.5E-29 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS20635 fbfea2129e6f5009aad2552b577638a3 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.46 T 29-03-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CSW12_RS20635 fbfea2129e6f5009aad2552b577638a3 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 6.1E-28 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CSW12_RS20635 fbfea2129e6f5009aad2552b577638a3 278 Gene3D G3DSA:3.30.930.10 3 278 5.2E-60 T 29-03-2018 CSW12_RS20635 fbfea2129e6f5009aad2552b577638a3 278 SUPERFAMILY SSF55681 5 278 1.49E-68 T 29-03-2018 CSW12_RS12310 141c15245b5c2d0aaca0fae4f048c97e 231 Pfam PF06149 Protein of unknown function (DUF969) 1 216 1.5E-86 T 29-03-2018 IPR010374 Protein of unknown function DUF969 CSW12_RS19540 fbcc8478e723cb9c2c778f98612f5244 113 Pfam PF04341 Protein of unknown function, DUF485 22 105 3.7E-23 T 29-03-2018 IPR007436 Protein of unknown function DUF485 CSW12_RS20615 ce999c41577de4bbc83024cb759a1296 341 SUPERFAMILY SSF102114 84 233 1.44E-5 T 29-03-2018 CSW12_RS20615 ce999c41577de4bbc83024cb759a1296 341 Gene3D G3DSA:3.80.30.20 78 302 9.4E-12 T 29-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CSW12_RS20615 ce999c41577de4bbc83024cb759a1296 341 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 4 341 2.9E-162 T 29-03-2018 IPR023897 Spore photoproduct lyase GO:0003913 CSW12_RS22810 9773e20400e8b53593c242731e4d1694 144 Gene3D G3DSA:3.90.79.10 1 143 7.0E-11 T 29-03-2018 CSW12_RS22810 9773e20400e8b53593c242731e4d1694 144 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 29-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CSW12_RS22810 9773e20400e8b53593c242731e4d1694 144 Pfam PF00293 NUDIX domain 5 123 3.5E-9 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS22810 9773e20400e8b53593c242731e4d1694 144 SUPERFAMILY SSF55811 3 122 6.77E-16 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS07055 83d253e7e9404b88e798502cd55e3ef6 78 Pfam PF13106 Domain of unknown function (DUF3961) 35 73 1.3E-31 T 29-03-2018 IPR025081 Domain of unknown function DUF3961 CSW12_RS04005 8112017c575bd8524d75b020af151c8f 35 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 9 32 3.1E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS04005 8112017c575bd8524d75b020af151c8f 35 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 11 34 1.7E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS13965 c7bb095ce6359984b9c390ad9cf1f180 348 Pfam PF06081 Aromatic acid exporter family member 1 10 148 5.6E-36 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CSW12_RS13675 aa77c87ae691586e06b2b37bb11e3ed7 235 Pfam PF08241 Methyltransferase domain 49 141 2.5E-25 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS13675 aa77c87ae691586e06b2b37bb11e3ed7 235 SUPERFAMILY SSF53335 1 200 1.53E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS13675 aa77c87ae691586e06b2b37bb11e3ed7 235 Gene3D G3DSA:3.40.50.150 1 232 2.3E-38 T 29-03-2018 CSW12_RS12165 e96dd725167bc26c88d966543fb82692 443 Gene3D G3DSA:3.30.1870.10 104 175 2.7E-20 T 29-03-2018 CSW12_RS12165 e96dd725167bc26c88d966543fb82692 443 Gene3D G3DSA:3.40.1660.10 293 442 1.3E-21 T 29-03-2018 CSW12_RS12165 e96dd725167bc26c88d966543fb82692 443 SUPERFAMILY SSF159501 41 441 2.41E-117 T 29-03-2018 CSW12_RS12165 e96dd725167bc26c88d966543fb82692 443 PIRSF PIRSF036794 23 443 5.6E-160 T 29-03-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type CSW12_RS12165 e96dd725167bc26c88d966543fb82692 443 Gene3D G3DSA:1.20.1440.30 178 292 1.6E-21 T 29-03-2018 CSW12_RS12165 e96dd725167bc26c88d966543fb82692 443 Pfam PF05139 Erythromycin esterase 102 435 1.6E-67 T 29-03-2018 IPR007815 Erythromycin esterase GO:0046677 CSW12_RS20330 67d9ea2fe30077ec5a979c11c1abebec 219 Gene3D G3DSA:1.10.3720.10 2 219 1.7E-42 T 29-03-2018 CSW12_RS20330 67d9ea2fe30077ec5a979c11c1abebec 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 2.4E-29 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CSW12_RS20330 67d9ea2fe30077ec5a979c11c1abebec 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 2.2E-20 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS20330 67d9ea2fe30077ec5a979c11c1abebec 219 SUPERFAMILY SSF161098 13 201 9.68E-45 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28700 4b682577e07d0a759bac6defa2d4c5e6 95 Gene3D G3DSA:1.10.1220.10 8 59 4.7E-7 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CSW12_RS08345 d83ced94cb804683c5224b5241a7e83e 210 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 210 30.289 T 29-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08345 d83ced94cb804683c5224b5241a7e83e 210 SUPERFAMILY SSF53271 2 203 6.95E-52 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS08345 d83ced94cb804683c5224b5241a7e83e 210 Gene3D G3DSA:3.40.50.2020 1 210 2.7E-41 T 29-03-2018 CSW12_RS08345 d83ced94cb804683c5224b5241a7e83e 210 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 8 175 1.3E-49 T 29-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CSW12_RS08345 d83ced94cb804683c5224b5241a7e83e 210 Pfam PF00156 Phosphoribosyl transferase domain 44 155 3.6E-19 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS10050 472674de4ce16e6811f0a017626b0698 206 Pfam PF01184 GPR1/FUN34/yaaH family 8 197 3.2E-23 T 29-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 CSW12_RS17675 b8e464094ba91242636e2367833b8d91 459 Pfam PF01943 Polysaccharide biosynthesis protein 7 319 9.4E-40 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS17675 b8e464094ba91242636e2367833b8d91 459 PIRSF PIRSF038958 1 458 5.0E-107 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CSW12_RS17675 b8e464094ba91242636e2367833b8d91 459 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 375 455 5.5E-19 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CSW12_RS12200 510a024b2e4fc46e247b8ad3c452a206 159 Pfam PF10710 Protein of unknown function (DUF2512) 2 141 7.0E-47 T 29-03-2018 IPR019649 Protein of unknown function DUF2512 CSW12_RS10510 acc16fa9cc61f78de783e1bf6cc0fdb5 236 PIRSF PIRSF000709 7 114 2.7E-6 T 29-03-2018 CSW12_RS10510 acc16fa9cc61f78de783e1bf6cc0fdb5 236 Gene3D G3DSA:3.40.50.1240 1 236 7.0E-47 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS10510 acc16fa9cc61f78de783e1bf6cc0fdb5 236 SUPERFAMILY SSF53254 14 232 5.76E-45 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS10510 acc16fa9cc61f78de783e1bf6cc0fdb5 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 15 223 2.0E-32 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS10510 acc16fa9cc61f78de783e1bf6cc0fdb5 236 SMART SM00855 14 188 4.4E-16 T 29-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 SMART SM00487 56 235 8.5E-30 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 Pfam PF00176 SNF2 family N-terminal domain 79 333 2.3E-36 T 29-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 Gene3D G3DSA:3.40.50.10810 37 265 2.5E-40 T 29-03-2018 CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 SMART SM00490 386 466 1.0E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 SUPERFAMILY SSF52540 16 241 2.47E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 Pfam PF00271 Helicase conserved C-terminal domain 363 466 2.8E-20 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 Gene3D G3DSA:3.40.50.300 344 504 2.1E-36 T 29-03-2018 CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 SUPERFAMILY SSF52540 168 222 5.65E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS20740 f02b25df6168532b20e74221ff6fbec1 560 SUPERFAMILY SSF52540 350 518 5.65E-55 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22385 e76b9bfebf936ec5b995493e4edcf390 94 SUPERFAMILY SSF102829 15 90 6.02E-21 T 29-03-2018 IPR007838 Cell division protein ZapA-like CSW12_RS22385 e76b9bfebf936ec5b995493e4edcf390 94 Pfam PF05164 Cell division protein ZapA 16 88 2.2E-18 T 29-03-2018 IPR007838 Cell division protein ZapA-like CSW12_RS22385 e76b9bfebf936ec5b995493e4edcf390 94 Hamap MF_02013 Cell division protein ZapA [zapA]. 8 92 28.685 T 29-03-2018 IPR023688 Cell division protein ZapA, firmicutes GO:0007049|GO:0051301 CSW12_RS03360 98f08284cfb958a869d5587fcb7c1850 438 Pfam PF05525 Branched-chain amino acid transport protein 8 428 2.8E-141 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS03360 98f08284cfb958a869d5587fcb7c1850 438 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 15 415 1.3E-127 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS30880 60c8a9dd578624b5d7bc0bf3f04ff6e0 67 SUPERFAMILY SSF47413 3 61 4.79E-13 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS30880 60c8a9dd578624b5d7bc0bf3f04ff6e0 67 Gene3D G3DSA:1.10.260.40 1 67 3.6E-12 T 29-03-2018 CSW12_RS30880 60c8a9dd578624b5d7bc0bf3f04ff6e0 67 SMART SM00530 2 57 4.6E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30880 60c8a9dd578624b5d7bc0bf3f04ff6e0 67 Pfam PF01381 Helix-turn-helix 5 57 1.0E-11 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS12035 e6c2f4fe08375d55e6be96f777dc10ac 868 Pfam PF10070 Uncharacterized protein conserved in bacteria (DUF2309) 24 854 2.6E-268 T 29-03-2018 IPR018752 Uncharacterised protein family UPF0753 CSW12_RS12035 e6c2f4fe08375d55e6be96f777dc10ac 868 Hamap MF_01871 UPF0753 protein . 19 868 24.26 T 29-03-2018 IPR018752 Uncharacterised protein family UPF0753 CSW12_RS14990 75bbe1e71bdbf9f8a2c7b378945887b2 169 Gene3D G3DSA:3.40.630.30 1 169 1.1E-25 T 29-03-2018 CSW12_RS14990 75bbe1e71bdbf9f8a2c7b378945887b2 169 Pfam PF13302 Acetyltransferase (GNAT) domain 4 138 3.7E-14 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS14990 75bbe1e71bdbf9f8a2c7b378945887b2 169 SUPERFAMILY SSF55729 2 163 1.17E-31 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS11990 880ec0d6d6b87621babbd95e2737de63 303 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 294 9.9E-35 T 29-03-2018 CSW12_RS11990 880ec0d6d6b87621babbd95e2737de63 303 PIRSF PIRSF005355 1 302 7.7E-84 T 29-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CSW12_RS11990 880ec0d6d6b87621babbd95e2737de63 303 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 297 18.544 T 29-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CSW12_RS11990 880ec0d6d6b87621babbd95e2737de63 303 Pfam PF01040 UbiA prenyltransferase family 27 254 3.0E-35 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 SUPERFAMILY SSF54593 189 301 3.49E-23 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 Gene3D G3DSA:3.10.180.10 68 244 1.2E-24 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 SUPERFAMILY SSF54593 5 163 3.03E-27 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 191 301 2.1E-4 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 150 1.9E-8 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 Gene3D G3DSA:3.10.180.10 245 303 0.071 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS10095 ff4ea1f5693b903d2240e734a8e9884b 306 Gene3D G3DSA:3.10.180.10 7 67 1.1E-7 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS26275 66d81141deeb12609a39f5ec0064317c 122 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 24 121 7.9E-38 T 29-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26275 66d81141deeb12609a39f5ec0064317c 122 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 5 122 19.659 T 29-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CSW12_RS18170 c2f5f9e8777436a2700a321f4446cb64 107 SUPERFAMILY SSF69118 8 103 1.12E-24 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS18170 c2f5f9e8777436a2700a321f4446cb64 107 Pfam PF02627 Carboxymuconolactone decarboxylase family 19 100 9.3E-20 T 29-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CSW12_RS18170 c2f5f9e8777436a2700a321f4446cb64 107 Gene3D G3DSA:1.20.1290.10 2 107 1.2E-25 T 29-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 SMART SM00387 216 327 1.4E-21 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 323 7.3E-20 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 Gene3D G3DSA:3.30.565.10 134 324 1.7E-36 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 3.6E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 272 282 3.6E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 254 268 3.6E-8 T 29-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CSW12_RS14745 675da5530e0a8c406d631ea0d10acb07 327 SUPERFAMILY SSF55874 163 324 4.32E-33 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS04440 d293c64228aefeaa7eab58c78af1fd34 283 SUPERFAMILY SSF158430 15 142 2.35E-39 T 29-03-2018 CSW12_RS04440 d293c64228aefeaa7eab58c78af1fd34 283 SUPERFAMILY SSF158430 148 271 1.29E-38 T 29-03-2018 CSW12_RS04440 d293c64228aefeaa7eab58c78af1fd34 283 Pfam PF11155 Domain of unknown function (DUF2935) 22 136 4.8E-32 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CSW12_RS04440 d293c64228aefeaa7eab58c78af1fd34 283 Pfam PF11155 Domain of unknown function (DUF2935) 151 267 1.8E-31 T 29-03-2018 IPR021328 Protein of unknown function DUF2935 CSW12_RS20255 d449af70ed4b54170972ef811d74ea0c 83 Pfam PF13068 Protein of unknown function (DUF3932) 1 81 7.5E-53 T 29-03-2018 IPR025173 Protein of unknown function DUF3932 CSW12_RS17950 ebb9551100cd0e65fcc83aecefdc5b22 610 Pfam PF06276 Ferric iron reductase FhuF-like transporter 409 579 1.3E-32 T 29-03-2018 IPR022770 Ferric iron reductase FhuF domain CSW12_RS17950 ebb9551100cd0e65fcc83aecefdc5b22 610 Pfam PF04183 IucA / IucC family 147 388 2.4E-70 T 29-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CSW12_RS23220 13fc9040860cd2b6fbff894efe852cd5 550 PIRSF PIRSF038958 1 537 5.9E-122 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CSW12_RS23220 13fc9040860cd2b6fbff894efe852cd5 550 Pfam PF01943 Polysaccharide biosynthesis protein 6 320 1.9E-44 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS23220 13fc9040860cd2b6fbff894efe852cd5 550 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 372 519 1.4E-29 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CSW12_RS06855 eb8fd4c179b26344424773fa2ae51ce6 332 Pfam PF01384 Phosphate transporter family 22 320 2.7E-90 T 29-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CSW12_RS06960 5b350673136611726439904078be7769 541 Pfam PF05140 ResB-like family 65 430 8.5E-74 T 29-03-2018 IPR007816 ResB-like domain CSW12_RS06960 5b350673136611726439904078be7769 541 Pfam PF05140 ResB-like family 439 519 4.2E-16 T 29-03-2018 IPR007816 ResB-like domain CSW12_RS12810 cf25e78b4707aec7a4b77838443a0109 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 299 8.6E-50 T 29-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CSW12_RS12810 cf25e78b4707aec7a4b77838443a0109 317 Gene3D G3DSA:1.10.3470.10 10 305 2.3E-34 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS28840 f330076d31d0c747149315dd31869777 63 Pfam PF14146 Domain of unknown function (DUF4305) 18 54 2.6E-14 T 29-03-2018 IPR025426 Protein of unknown function DUF4305 CSW12_RS28840 f330076d31d0c747149315dd31869777 63 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 63 0.003 T 29-03-2018 CSW12_RS13820 cf580e96d99e4e25f34ce6e31e38df33 178 Pfam PF13315 Protein of unknown function (DUF4085) 1 169 5.2E-74 T 29-03-2018 IPR025144 Protein of unknown function DUF4085 CSW12_RS01430 3ddd6e2c8aea399c0902635601d0a3fe 295 Gene3D G3DSA:3.90.1720.10 129 293 3.2E-12 T 29-03-2018 CSW12_RS01430 3ddd6e2c8aea399c0902635601d0a3fe 295 Pfam PF12671 Putative amidase domain 136 289 8.9E-37 T 29-03-2018 IPR024301 Putative amidase domain CSW12_RS03055 90b0c34955a5354e8033006dcb05a7b3 284 Gene3D G3DSA:3.40.1090.10 3 279 7.1E-33 T 29-03-2018 CSW12_RS03055 90b0c34955a5354e8033006dcb05a7b3 284 Pfam PF01734 Patatin-like phospholipase 7 171 2.4E-19 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CSW12_RS03055 90b0c34955a5354e8033006dcb05a7b3 284 SUPERFAMILY SSF52151 5 275 2.62E-46 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS19795 56397bbd4d54c82f3a6f66ca35126062 111 Pfam PF05103 DivIVA protein 8 66 3.2E-19 T 29-03-2018 IPR007793 DivIVA family CSW12_RS19795 56397bbd4d54c82f3a6f66ca35126062 111 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 4.0E-16 T 29-03-2018 IPR019933 DivIVA domain CSW12_RS19795 56397bbd4d54c82f3a6f66ca35126062 111 Gene3D G3DSA:1.20.5.1180 27 74 3.7E-4 T 29-03-2018 CSW12_RS19795 56397bbd4d54c82f3a6f66ca35126062 111 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 107 23.874 T 29-03-2018 IPR011229 Cell cycle protein GpsB CSW12_RS19795 56397bbd4d54c82f3a6f66ca35126062 111 PIRSF PIRSF029938 1 111 9.0E-49 T 29-03-2018 IPR011229 Cell cycle protein GpsB CSW12_RS15295 8a8398c6c2d8e96ec9c325ce84b94efa 424 Gene3D G3DSA:1.20.1440.110 27 121 1.7E-13 T 29-03-2018 CSW12_RS15295 8a8398c6c2d8e96ec9c325ce84b94efa 424 SUPERFAMILY SSF53474 34 369 4.37E-50 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS15295 8a8398c6c2d8e96ec9c325ce84b94efa 424 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 48 306 3.0E-17 T 29-03-2018 IPR010520 UPF0255 family CSW12_RS15295 8a8398c6c2d8e96ec9c325ce84b94efa 424 Gene3D G3DSA:3.40.50.1820 122 369 1.0E-24 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS11605 3fdc0f7bbc811ae82664590b219dbddf 136 Pfam PF11528 Protein of unknown function (DUF3224) 4 123 4.4E-21 T 29-03-2018 IPR021607 Protein of unknown function DUF3224 CSW12_RS11605 3fdc0f7bbc811ae82664590b219dbddf 136 Gene3D G3DSA:2.40.350.10 1 136 8.2E-28 T 29-03-2018 IPR023159 SO1590-like domain CSW12_RS11605 3fdc0f7bbc811ae82664590b219dbddf 136 SUPERFAMILY SSF159238 2 131 7.98E-32 T 29-03-2018 IPR023159 SO1590-like domain CSW12_RS03470 7980bdb333971dfdb35ae7e2d7c26954 134 Pfam PF07681 DoxX 7 85 9.6E-20 T 29-03-2018 IPR032808 DoxX family CSW12_RS04115 b82fecab805c3e43389c98511033a366 103 SUPERFAMILY SSF46785 4 101 1.43E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04115 b82fecab805c3e43389c98511033a366 103 SMART SM00418 5 100 5.3E-4 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS04115 b82fecab805c3e43389c98511033a366 103 Gene3D G3DSA:1.10.10.10 6 90 1.3E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11455 48e2e6ca3672a1dc2bdeadf47b126f86 301 SUPERFAMILY SSF52540 3 219 2.28E-63 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS11455 48e2e6ca3672a1dc2bdeadf47b126f86 301 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS11455 48e2e6ca3672a1dc2bdeadf47b126f86 301 Gene3D G3DSA:3.40.50.300 2 261 8.6E-66 T 29-03-2018 CSW12_RS11455 48e2e6ca3672a1dc2bdeadf47b126f86 301 SMART SM00382 27 204 2.1E-13 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS11455 48e2e6ca3672a1dc2bdeadf47b126f86 301 Pfam PF00005 ABC transporter 19 157 2.8E-34 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS11455 48e2e6ca3672a1dc2bdeadf47b126f86 301 Pfam PF13732 Domain of unknown function (DUF4162) 212 298 8.6E-8 T 29-03-2018 IPR025302 Domain of unknown function DUF4162 CSW12_RS02175 6ae7beb4a6238b490ff65d0c8cb357b7 383 Pfam PF05065 Phage capsid family 90 258 1.7E-9 T 29-03-2018 IPR024455 Phage capsid CSW12_RS02175 6ae7beb4a6238b490ff65d0c8cb357b7 383 Gene3D G3DSA:3.30.2400.10 78 262 6.6E-13 T 29-03-2018 CSW12_RS02175 6ae7beb4a6238b490ff65d0c8cb357b7 383 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 62 235 7.5E-13 T 29-03-2018 IPR024455 Phage capsid CSW12_RS02175 6ae7beb4a6238b490ff65d0c8cb357b7 383 SUPERFAMILY SSF56563 90 364 4.32E-14 T 29-03-2018 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 8.8E-82 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 Gene3D G3DSA:3.40.470.10 1 223 3.4E-100 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 SMART SM00987 50 210 2.5E-36 T 29-03-2018 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 Pfam PF03167 Uracil DNA glycosylase superfamily 54 209 1.5E-26 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 29-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 SMART SM00986 50 210 2.5E-36 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 SUPERFAMILY SSF52141 3 221 5.61E-93 T 29-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS26775 6401732e387e76316a6d665f67381ff4 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 41.018 T 29-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CSW12_RS17480 c30c5b6bb59c1ead514643249d42e66f 292 SUPERFAMILY SSF56112 4 274 5.87E-15 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS17480 c30c5b6bb59c1ead514643249d42e66f 292 Gene3D G3DSA:3.90.1200.10 115 280 9.2E-9 T 29-03-2018 CSW12_RS17900 45bb69898b9e6096fd0874761f8a40f9 321 Gene3D G3DSA:3.40.1090.10 4 319 6.0E-45 T 29-03-2018 CSW12_RS17900 45bb69898b9e6096fd0874761f8a40f9 321 SUPERFAMILY SSF52151 6 303 2.49E-45 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS17900 45bb69898b9e6096fd0874761f8a40f9 321 Pfam PF01734 Patatin-like phospholipase 6 198 1.7E-31 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CSW12_RS18575 0e52c9e86f01cc03ae003f32f0dab889 238 Pfam PF04474 Protein of unknown function (DUF554) 4 226 9.8E-74 T 29-03-2018 IPR007563 Protein of unknown function DUF554 CSW12_RS00505 68313ea6876cb92bc2424b7668f18ea8 184 Gene3D G3DSA:3.10.450.100 84 181 0.0066 T 29-03-2018 CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 SUPERFAMILY SSF88946 5 107 1.1E-12 T 29-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 Gene3D G3DSA:1.10.10.10 118 177 1.5E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 SUPERFAMILY SSF88659 119 176 5.05E-13 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 173 1.4E-16 T 29-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 Gene3D G3DSA:1.10.1740.10 3 117 2.7E-13 T 29-03-2018 CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 Pfam PF08281 Sigma-70, region 4 119 171 6.5E-12 T 29-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS19485 908afeca83d62d4117fac56b6b0a93f3 179 Pfam PF04542 Sigma-70 region 2 25 92 6.5E-6 T 29-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS16725 68c86c30c705def2f062f0b8cac0ebd3 505 SUPERFAMILY SSF56349 260 314 4.12E-22 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS16725 68c86c30c705def2f062f0b8cac0ebd3 505 SUPERFAMILY SSF56349 353 481 4.12E-22 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS16725 68c86c30c705def2f062f0b8cac0ebd3 505 Gene3D G3DSA:1.10.443.10 259 485 1.6E-25 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS16725 68c86c30c705def2f062f0b8cac0ebd3 505 Pfam PF00589 Phage integrase family 260 479 2.5E-16 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS23395 fa18074ac8ea55db0a094d7e1b22998e 407 Pfam PF00999 Sodium/hydrogen exchanger family 12 374 1.8E-59 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CSW12_RS23395 fa18074ac8ea55db0a094d7e1b22998e 407 Gene3D G3DSA:1.20.91.10 234 314 2.6E-7 T 29-03-2018 CSW12_RS10275 95807792fb3c93cf290825a5034e6d3a 224 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 13 179 1.6E-42 T 29-03-2018 IPR014903 Protein of unknown function DUF1796 CSW12_RS04260 897cbc40152ca4dcf092d79efa0f4790 66 Gene3D G3DSA:1.10.1470.10 6 66 7.6E-12 T 29-03-2018 IPR008462 CsbD-like domain CSW12_RS04260 897cbc40152ca4dcf092d79efa0f4790 66 SUPERFAMILY SSF69047 7 63 3.4E-11 T 29-03-2018 IPR008462 CsbD-like domain CSW12_RS04260 897cbc40152ca4dcf092d79efa0f4790 66 Pfam PF05532 CsbD-like 8 60 3.8E-14 T 29-03-2018 IPR008462 CsbD-like domain CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 SUPERFAMILY SSF53807 37 314 1.57E-54 T 29-03-2018 CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 Gene3D G3DSA:3.40.50.1980 35 158 5.8E-31 T 29-03-2018 CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 Pfam PF01497 Periplasmic binding protein 55 298 7.0E-30 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 301 314 3.1E-6 T 29-03-2018 IPR008091 Ferrichrome-binding periplasmic protein CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 104 119 3.1E-6 T 29-03-2018 IPR008091 Ferrichrome-binding periplasmic protein CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 72 90 3.1E-6 T 29-03-2018 IPR008091 Ferrichrome-binding periplasmic protein CSW12_RS22235 9017a040c46e5f8962d2a8df138e09d3 324 Gene3D G3DSA:3.40.50.1980 159 324 2.0E-22 T 29-03-2018 CSW12_RS25420 5963bdb04496cb6d5285c2dbda128b32 158 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 13 152 4.0E-64 T 29-03-2018 IPR014203 Sporulation stage V, protein AC CSW12_RS25420 5963bdb04496cb6d5285c2dbda128b32 158 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 31 148 3.3E-38 T 29-03-2018 IPR005562 SpoVA CSW12_RS22080 ac9fae0fbb341ca25181bc195d149891 227 SUPERFAMILY SSF52317 1 225 3.15E-71 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS22080 ac9fae0fbb341ca25181bc195d149891 227 Gene3D G3DSA:3.40.50.880 1 227 3.6E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS22080 ac9fae0fbb341ca25181bc195d149891 227 Pfam PF01965 DJ-1/PfpI family 28 213 3.1E-10 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS13140 efbfd42e38286016a37533ad233487be 197 Pfam PF16107 Domain of unknown function (DUF4825) 39 130 6.0E-14 T 29-03-2018 IPR032250 Domain of unknown function DUF4825 CSW12_RS19595 7cf207e099a06e1724879534b1659a93 128 Pfam PF13456 Reverse transcriptase-like 7 124 3.3E-20 T 29-03-2018 CSW12_RS19595 7cf207e099a06e1724879534b1659a93 128 SUPERFAMILY SSF53098 2 122 6.07E-32 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS19595 7cf207e099a06e1724879534b1659a93 128 Gene3D G3DSA:3.30.420.10 1 128 2.9E-27 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS26220 ca9b462f3cb72fa19bd20eb65019b8d5 78 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 10 76 4.3E-31 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 CSW12_RS26220 ca9b462f3cb72fa19bd20eb65019b8d5 78 Pfam PF06612 Protein of unknown function (DUF1146) 17 64 2.8E-20 T 29-03-2018 IPR009526 Protein of unknown function DUF1146 CSW12_RS24030 93ac7a976aea81bbd05f17e58b57d639 464 SUPERFAMILY SSF56322 29 460 2.49E-104 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS24030 93ac7a976aea81bbd05f17e58b57d639 464 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 110 458 4.5E-105 T 29-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CSW12_RS24030 93ac7a976aea81bbd05f17e58b57d639 464 Pfam PF00425 chorismate binding enzyme 201 451 9.2E-73 T 29-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CSW12_RS24030 93ac7a976aea81bbd05f17e58b57d639 464 Gene3D G3DSA:3.60.120.10 2 462 1.8E-96 T 29-03-2018 IPR005801 ADC synthase GO:0009058 CSW12_RS07580 e300fe61543ab7d843c13282aef8a0df 250 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 160 205 3.3E-7 T 29-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CSW12_RS07580 e300fe61543ab7d843c13282aef8a0df 250 Gene3D G3DSA:3.40.50.300 12 123 2.1E-9 T 29-03-2018 CSW12_RS07580 e300fe61543ab7d843c13282aef8a0df 250 Gene3D G3DSA:3.40.50.300 132 234 2.2E-9 T 29-03-2018 CSW12_RS07580 e300fe61543ab7d843c13282aef8a0df 250 SUPERFAMILY SSF52540 34 214 4.25E-22 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS07580 e300fe61543ab7d843c13282aef8a0df 250 Pfam PF13476 AAA domain 34 84 3.9E-10 T 29-03-2018 CSW12_RS07580 e300fe61543ab7d843c13282aef8a0df 250 SMART SM00382 39 217 1.0E-6 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS13405 7f2a597c695f7ac4641a86b9da74564b 76 Gene3D G3DSA:1.10.10.10 8 76 1.3E-6 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13405 7f2a597c695f7ac4641a86b9da74564b 76 SUPERFAMILY SSF46785 14 75 9.28E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03475 336e605b20cbff0129acb3d62e41b47e 133 Gene3D G3DSA:3.10.450.50 1 133 1.5E-17 T 29-03-2018 CSW12_RS03475 336e605b20cbff0129acb3d62e41b47e 133 Pfam PF12680 SnoaL-like domain 13 117 1.1E-9 T 29-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CSW12_RS03475 336e605b20cbff0129acb3d62e41b47e 133 SUPERFAMILY SSF54427 3 131 1.55E-32 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS13180 1f28ab6fe367aa02388e6c10cd2ef541 132 Gene3D G3DSA:3.10.129.10 1 130 7.2E-32 T 29-03-2018 CSW12_RS13180 1f28ab6fe367aa02388e6c10cd2ef541 132 SUPERFAMILY SSF54637 3 126 2.36E-29 T 29-03-2018 IPR029069 HotDog domain CSW12_RS13180 1f28ab6fe367aa02388e6c10cd2ef541 132 Pfam PF07977 FabA-like domain 7 123 9.3E-16 T 29-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CSW12_RS00240 5d8ac88cb3b21fcf3f509384b9be5e9d 161 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 7 151 3.0E-21 T 29-03-2018 IPR006524 Transcription activator, ArpU family CSW12_RS09425 f6da790707136665cf4a78d97c02b827 314 Pfam PF12679 ABC-2 family transporter protein 3 313 1.6E-16 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CSW12_RS17780 2a6beec5e230d5822b011fa46e0e076e 314 SUPERFAMILY SSF53474 122 305 2.36E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS17780 2a6beec5e230d5822b011fa46e0e076e 314 Pfam PF02230 Phospholipase/Carboxylesterase 195 296 1.9E-6 T 29-03-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CSW12_RS17780 2a6beec5e230d5822b011fa46e0e076e 314 Gene3D G3DSA:3.40.50.1820 118 311 9.2E-16 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12245 630bb0b430cefda72e7253472210d018 292 Pfam PF01636 Phosphotransferase enzyme family 31 254 1.0E-33 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS12245 630bb0b430cefda72e7253472210d018 292 Gene3D G3DSA:3.90.1200.10 93 288 2.4E-19 T 29-03-2018 CSW12_RS12245 630bb0b430cefda72e7253472210d018 292 SUPERFAMILY SSF56112 12 262 2.19E-46 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS11375 cc1343c0b4b56e2ca16e30cb83ad2dd4 476 Pfam PF03606 C4-dicarboxylate anaerobic carrier 18 469 1.0E-87 T 29-03-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 CSW12_RS19940 f389e79249984082cc93aa592b96c5a1 113 SUPERFAMILY SSF101386 4 104 1.96E-28 T 29-03-2018 CSW12_RS19940 f389e79249984082cc93aa592b96c5a1 113 PIRSF PIRSF029904 1 111 1.4E-56 T 29-03-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CSW12_RS19940 f389e79249984082cc93aa592b96c5a1 113 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 104 4.8E-20 T 29-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CSW12_RS19940 f389e79249984082cc93aa592b96c5a1 113 Gene3D G3DSA:1.10.3420.10 1 110 3.5E-30 T 29-03-2018 CSW12_RS01555 cf1e3e9e90435da586f3fb111b5c60da 273 SUPERFAMILY SSF161098 5 273 1.12E-63 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01555 cf1e3e9e90435da586f3fb111b5c60da 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 264 7.2E-13 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS01555 cf1e3e9e90435da586f3fb111b5c60da 273 Gene3D G3DSA:1.10.3720.10 3 261 2.2E-35 T 29-03-2018 CSW12_RS12010 8d2412710395f9eda4a902aeaa7c94ee 397 Pfam PF12698 ABC-2 family transporter protein 21 377 3.5E-26 T 29-03-2018 CSW12_RS12010 8d2412710395f9eda4a902aeaa7c94ee 397 Gene3D G3DSA:3.40.1710.10 35 217 4.0E-24 T 29-03-2018 CSW12_RS24770 30f793cfb003005292a487c18c0754a8 121 Gene3D G3DSA:3.40.30.10 1 117 1.8E-37 T 29-03-2018 CSW12_RS24770 30f793cfb003005292a487c18c0754a8 121 SUPERFAMILY SSF52833 2 117 7.0E-37 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS24770 30f793cfb003005292a487c18c0754a8 121 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 2.6E-34 T 29-03-2018 IPR006504 Transcriptional regulator Spx/MgsR CSW12_RS24770 30f793cfb003005292a487c18c0754a8 121 Pfam PF03960 ArsC family 10 114 1.7E-16 T 29-03-2018 IPR006660 Arsenate reductase-like CSW12_RS19235 3d0897df4e8f447fb2e043dc0bdb06a9 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.9E-13 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CSW12_RS19235 3d0897df4e8f447fb2e043dc0bdb06a9 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.9E-13 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CSW12_RS19235 3d0897df4e8f447fb2e043dc0bdb06a9 91 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.9E-13 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CSW12_RS19235 3d0897df4e8f447fb2e043dc0bdb06a9 91 Pfam PF01313 Bacterial export proteins, family 3 6 75 7.1E-19 T 29-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CSW12_RS19400 13bfdaca0a96308ea2d3379602772d96 165 Gene3D G3DSA:3.20.20.150 49 160 0.06 T 29-03-2018 CSW12_RS05335 326968c9a96e08b1e04bf0290d29a620 89 Gene3D G3DSA:1.20.900.10 1 88 2.4E-4 T 29-03-2018 CSW12_RS06550 d8af5a33e92ad9e3c502265aca5da487 79 Pfam PF13050 Protein of unknown function (DUF3911) 1 77 1.1E-53 T 29-03-2018 IPR025022 Protein of unknown function DUF3911 CSW12_RS14855 ed261e765a645c4c24fb971db7223a22 250 SUPERFAMILY SSF56112 6 224 6.03E-27 T 29-03-2018 IPR011009 Protein kinase-like domain CSW12_RS14855 ed261e765a645c4c24fb971db7223a22 250 Gene3D G3DSA:1.10.510.10 31 250 4.4E-13 T 29-03-2018 CSW12_RS14855 ed261e765a645c4c24fb971db7223a22 250 Pfam PF01636 Phosphotransferase enzyme family 31 209 7.2E-12 T 29-03-2018 IPR002575 Aminoglycoside phosphotransferase CSW12_RS20995 e603d807a473adf70bbef72397a368b4 252 Pfam PF06691 Protein of unknown function (DUF1189) 4 243 1.8E-65 T 29-03-2018 IPR009574 Protein of unknown function DUF1189 CSW12_RS17560 c83430a3f7282545f71408a3017dbe01 165 Gene3D G3DSA:3.40.630.30 1 165 6.4E-33 T 29-03-2018 CSW12_RS17560 c83430a3f7282545f71408a3017dbe01 165 Pfam PF00583 Acetyltransferase (GNAT) family 36 138 2.5E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17560 c83430a3f7282545f71408a3017dbe01 165 SUPERFAMILY SSF55729 2 164 3.99E-35 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS09830 3d9390de2e1e91b91fb077020150566e 239 Gene3D G3DSA:3.40.50.150 18 228 1.7E-26 T 29-03-2018 CSW12_RS09830 3d9390de2e1e91b91fb077020150566e 239 SUPERFAMILY SSF53335 12 218 8.13E-36 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS09830 3d9390de2e1e91b91fb077020150566e 239 Pfam PF13649 Methyltransferase domain 41 133 5.6E-17 T 29-03-2018 CSW12_RS25895 1110257b21303e46449269f0c05a1692 163 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 2 154 2.5E-44 T 29-03-2018 IPR019250 Protein of unknown function DUF2227, metal-binding CSW12_RS27080 075471faf0e2101e88cbe88db33aee94 221 Pfam PF00089 Trypsin 22 111 1.7E-4 T 29-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CSW12_RS27080 075471faf0e2101e88cbe88db33aee94 221 Gene3D G3DSA:2.40.10.10 113 210 7.4E-9 T 29-03-2018 CSW12_RS27080 075471faf0e2101e88cbe88db33aee94 221 SUPERFAMILY SSF50494 23 171 6.85E-12 T 29-03-2018 IPR009003 Peptidase S1, PA clan CSW12_RS27080 075471faf0e2101e88cbe88db33aee94 221 Gene3D G3DSA:2.40.10.10 13 112 4.2E-9 T 29-03-2018 CSW12_RS11460 c596ec7e9e9ffae895725c6914d12dfb 262 Pfam PF13346 ABC-2 family transporter protein 82 253 1.3E-5 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CSW12_RS16565 e168965579d00cef08bbd1d7cc40c54f 475 PIRSF PIRSF006060 4 469 3.6E-59 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS16565 e168965579d00cef08bbd1d7cc40c54f 475 Pfam PF13520 Amino acid permease 12 414 2.7E-68 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS16565 e168965579d00cef08bbd1d7cc40c54f 475 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 9 474 3.6E-171 T 29-03-2018 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 CSW12_RS09585 eeeba09c07348b585c21908fa6de34db 268 Gene3D G3DSA:3.40.630.30 115 252 3.0E-12 T 29-03-2018 CSW12_RS09585 eeeba09c07348b585c21908fa6de34db 268 SUPERFAMILY SSF55729 94 240 9.78E-15 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 SUPERFAMILY SSF53850 3 206 3.12E-66 T 29-03-2018 CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 29-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 Gene3D G3DSA:3.40.190.10 1 116 6.6E-39 T 29-03-2018 CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 Pfam PF01634 ATP phosphoribosyltransferase 53 204 9.6E-51 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 3 208 59.446 T 29-03-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 184 8.3E-63 T 29-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CSW12_RS06605 e5921f05887565d9b507dc4c8add87c2 211 Gene3D G3DSA:3.40.190.10 117 209 4.2E-24 T 29-03-2018 CSW12_RS26285 3fd46e66126a54a7fe2131cf3ce26ac6 214 Pfam PF06161 Protein of unknown function (DUF975) 119 207 5.5E-29 T 29-03-2018 IPR010380 Protein of unknown function DUF975 CSW12_RS26285 3fd46e66126a54a7fe2131cf3ce26ac6 214 Pfam PF06161 Protein of unknown function (DUF975) 2 127 1.9E-14 T 29-03-2018 IPR010380 Protein of unknown function DUF975 CSW12_RS19390 c503eb52eb61d7c28cd8c97b7d6336cb 150 Gene3D G3DSA:1.20.58.300 4 131 2.1E-5 T 29-03-2018 CSW12_RS06765 00ad077ce5a7eb15446d75ae3de92819 220 Pfam PF04012 PspA/IM30 family 5 208 1.7E-28 T 29-03-2018 IPR007157 PspA/IM30 CSW12_RS06765 00ad077ce5a7eb15446d75ae3de92819 220 Gene3D G3DSA:1.20.5.50 67 217 4.7E-7 T 29-03-2018 CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 2.3E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 Gene3D G3DSA:1.10.10.10 2 93 6.1E-15 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 SMART SM00418 17 96 6.4E-20 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 Pfam PF12840 Helix-turn-helix domain 16 75 9.0E-10 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS20905 45e6087d52e0c1c78b4dc85d5766924c 96 SUPERFAMILY SSF46785 5 95 1.37E-22 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16715 d14f201085acbf2eceef60372bc408b7 805 Gene3D G3DSA:1.10.443.10 371 575 7.0E-21 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS16715 d14f201085acbf2eceef60372bc408b7 805 Pfam PF00589 Phage integrase family 376 571 1.9E-12 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS16715 d14f201085acbf2eceef60372bc408b7 805 SUPERFAMILY SSF56349 277 573 2.8E-21 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS07700 2f94ee11d584c54a34a2adac4b3d2ae4 249 Gene3D G3DSA:1.10.1660.10 1 77 4.6E-4 T 29-03-2018 CSW12_RS07700 2f94ee11d584c54a34a2adac4b3d2ae4 249 Pfam PF13152 Protein of unknown function (DUF3967) 201 232 1.7E-14 T 29-03-2018 IPR025052 Domain of unknown function DUF3967 CSW12_RS26265 9ff5ffa9de3db4b00615dc8d312ee9d0 449 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 328 443 2.1E-40 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26265 9ff5ffa9de3db4b00615dc8d312ee9d0 449 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 380 435 2.0E-26 T 29-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26265 9ff5ffa9de3db4b00615dc8d312ee9d0 449 SUPERFAMILY SSF143243 300 446 7.32E-42 T 29-03-2018 CSW12_RS26265 9ff5ffa9de3db4b00615dc8d312ee9d0 449 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 330 443 4.1E-37 T 29-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS09380 41ae673960c3a13329ffac665254af7a 251 Pfam PF01925 Sulfite exporter TauE/SafE 4 245 4.5E-39 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS02150 6bec9fb46ada35a6e43bc857d3f80514 111 Pfam PF01844 HNH endonuclease 34 95 4.7E-9 T 29-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CSW12_RS02150 6bec9fb46ada35a6e43bc857d3f80514 111 SMART SM00507 21 91 2.7E-6 T 29-03-2018 IPR003615 HNH nuclease CSW12_RS02150 6bec9fb46ada35a6e43bc857d3f80514 111 Gene3D G3DSA:3.40.1800.10 6 110 1.3E-10 T 29-03-2018 CSW12_RS19555 66bd81a2cd08baaf1299363e614cd375 210 Pfam PF01810 LysE type translocator 13 204 2.1E-30 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS24720 21ae25bd201e55049ae3cfc929cbf3d9 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS24720 21ae25bd201e55049ae3cfc929cbf3d9 261 Gene3D G3DSA:3.40.50.300 3 251 3.7E-43 T 29-03-2018 CSW12_RS24720 21ae25bd201e55049ae3cfc929cbf3d9 261 Pfam PF00005 ABC transporter 21 173 8.9E-22 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS24720 21ae25bd201e55049ae3cfc929cbf3d9 261 SMART SM00382 30 225 2.1E-7 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS24720 21ae25bd201e55049ae3cfc929cbf3d9 261 SUPERFAMILY SSF52540 6 233 5.45E-44 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS24720 21ae25bd201e55049ae3cfc929cbf3d9 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 2.2E-113 T 29-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CSW12_RS05820 bb0f90b126b43be747d969bcc0861d3f 513 SUPERFAMILY SSF55469 417 501 2.62E-9 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS05820 bb0f90b126b43be747d969bcc0861d3f 513 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 59 227 3.8E-53 T 29-03-2018 IPR020051 SagB-type dehydrogenase domain CSW12_RS05820 bb0f90b126b43be747d969bcc0861d3f 513 Pfam PF00881 Nitroreductase family 410 499 4.7E-8 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS05820 bb0f90b126b43be747d969bcc0861d3f 513 Gene3D G3DSA:3.40.109.10 2 227 2.2E-20 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS05820 bb0f90b126b43be747d969bcc0861d3f 513 Gene3D G3DSA:3.40.109.10 260 502 5.0E-21 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS11430 d114b32dbe3fb3eb2ef1f671b9cfdecb 191 SUPERFAMILY SSF52218 2 191 2.64E-53 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS11430 d114b32dbe3fb3eb2ef1f671b9cfdecb 191 Pfam PF02525 Flavodoxin-like fold 2 174 8.7E-42 T 29-03-2018 IPR003680 Flavodoxin-like fold CSW12_RS11430 d114b32dbe3fb3eb2ef1f671b9cfdecb 191 Gene3D G3DSA:3.40.50.360 2 191 3.9E-42 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS24335 fd50007dfe603e94bf21b10e05258ad4 207 Pfam PF00929 Exonuclease 8 173 5.4E-22 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS24335 fd50007dfe603e94bf21b10e05258ad4 207 Gene3D G3DSA:3.30.420.10 1 184 3.2E-33 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS24335 fd50007dfe603e94bf21b10e05258ad4 207 SUPERFAMILY SSF53098 4 178 1.68E-31 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS24335 fd50007dfe603e94bf21b10e05258ad4 207 SMART SM00479 5 182 3.1E-32 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS28155 543b84560c6143b1e3eae894ee510d07 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 2.1E-46 T 29-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CSW12_RS28155 543b84560c6143b1e3eae894ee510d07 130 SUPERFAMILY SSF54211 5 130 7.59E-50 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS28155 543b84560c6143b1e3eae894ee510d07 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 29-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CSW12_RS28155 543b84560c6143b1e3eae894ee510d07 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 34.859 T 29-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CSW12_RS28155 543b84560c6143b1e3eae894ee510d07 130 Gene3D G3DSA:3.30.230.10 3 130 9.4E-53 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Gene3D G3DSA:2.60.120.40 190 321 1.5E-24 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Pfam PF01391 Collagen triple helix repeat (20 copies) 82 135 7.6E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Pfam PF01391 Collagen triple helix repeat (20 copies) 37 92 6.2E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Pfam PF01391 Collagen triple helix repeat (20 copies) 127 185 1.6E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Gene3D G3DSA:2.160.20.50 83 129 1.4E-16 T 29-03-2018 CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Gene3D G3DSA:2.160.20.50 130 189 1.3E-18 T 29-03-2018 CSW12_RS22230 923ced5df2e39a3f76cf8c82da1c27af 321 Gene3D G3DSA:2.160.20.50 5 82 2.3E-16 T 29-03-2018 CSW12_RS17430 a2445746d1a6dc9085cba0bd476e425f 121 Gene3D G3DSA:2.60.120.10 5 107 1.4E-7 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS17430 a2445746d1a6dc9085cba0bd476e425f 121 SUPERFAMILY SSF51182 16 100 3.73E-9 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS07800 9687d8553fbc30dbfd63b8d2167d1482 78 SUPERFAMILY SSF143567 2 77 1.16E-27 T 29-03-2018 CSW12_RS07800 9687d8553fbc30dbfd63b8d2167d1482 78 PIRSF PIRSF037356 1 78 5.7E-36 T 29-03-2018 IPR014904 Protein of unknown function DUF1797 CSW12_RS07800 9687d8553fbc30dbfd63b8d2167d1482 78 Pfam PF08796 Protein of unknown function (DUF1797) 7 77 2.0E-27 T 29-03-2018 IPR014904 Protein of unknown function DUF1797 CSW12_RS10220 27ccbb996b02c795fe2f7b98caab6304 182 Pfam PF06268 Fascin domain 56 135 3.2E-6 T 29-03-2018 IPR022768 Fascin domain GO:0030674|GO:0051015 CSW12_RS10220 27ccbb996b02c795fe2f7b98caab6304 182 SUPERFAMILY SSF50405 58 180 4.9E-26 T 29-03-2018 IPR008999 Actin cross-linking CSW12_RS10220 27ccbb996b02c795fe2f7b98caab6304 182 Gene3D G3DSA:2.80.10.50 136 181 4.3E-5 T 29-03-2018 CSW12_RS10220 27ccbb996b02c795fe2f7b98caab6304 182 Gene3D G3DSA:2.80.10.50 33 135 5.7E-20 T 29-03-2018 CSW12_RS14190 970c7630c9e9d1bb3fe974f1495789dd 175 Gene3D G3DSA:3.40.630.30 45 173 1.2E-15 T 29-03-2018 CSW12_RS14190 970c7630c9e9d1bb3fe974f1495789dd 175 Pfam PF13302 Acetyltransferase (GNAT) domain 3 143 4.9E-18 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS14190 970c7630c9e9d1bb3fe974f1495789dd 175 SUPERFAMILY SSF55729 3 145 1.71E-26 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS05610 b9bb37e679e3aca6f67f455501918d21 245 Gene3D G3DSA:3.90.550.10 1 243 6.5E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05610 b9bb37e679e3aca6f67f455501918d21 245 SUPERFAMILY SSF53448 2 235 5.42E-68 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05610 b9bb37e679e3aca6f67f455501918d21 245 Pfam PF00483 Nucleotidyl transferase 2 231 8.8E-53 T 29-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CSW12_RS06490 0d53d4297db6f426914cfda224b39909 263 Pfam PF02673 Bacitracin resistance protein BacA 8 257 8.2E-83 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS06490 0d53d4297db6f426914cfda224b39909 263 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 262 17.614 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS06490 0d53d4297db6f426914cfda224b39909 263 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 8 255 1.2E-86 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS13080 1877434ed3713446a8dc09a5b8f713d9 370 Gene3D G3DSA:3.20.20.30 1 358 2.9E-94 T 29-03-2018 CSW12_RS13080 1877434ed3713446a8dc09a5b8f713d9 370 Pfam PF00296 Luciferase-like monooxygenase 1 323 4.3E-92 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CSW12_RS13080 1877434ed3713446a8dc09a5b8f713d9 370 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 2 370 69.332 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 CSW12_RS13080 1877434ed3713446a8dc09a5b8f713d9 370 SUPERFAMILY SSF51679 1 349 1.18E-100 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CSW12_RS13080 1877434ed3713446a8dc09a5b8f713d9 370 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 347 1.6E-190 T 29-03-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 CSW12_RS10935 496e05d14ea4b5e30bb2742516e84783 137 SUPERFAMILY SSF46785 2 131 5.79E-28 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10935 496e05d14ea4b5e30bb2742516e84783 137 Pfam PF02082 Transcriptional regulator 2 79 1.0E-20 T 29-03-2018 IPR000944 Transcription regulator Rrf2-type CSW12_RS10935 496e05d14ea4b5e30bb2742516e84783 137 Gene3D G3DSA:1.10.10.10 1 137 6.3E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 Pfam PF00717 Peptidase S24-like 34 102 2.8E-18 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 ProSitePatterns PS00501 Signal peptidases I serine active site. 36 43 - T 29-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 13 170 3.5E-49 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 SUPERFAMILY SSF51306 30 175 8.24E-44 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 27 43 1.1E-13 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 128 147 1.1E-13 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 1.1E-13 T 29-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 ProSitePatterns PS00761 Signal peptidases I signature 3. 133 146 - T 29-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CSW12_RS14555 39dbc0378b6cd258f61c7d208d61911b 176 Gene3D G3DSA:2.10.109.10 24 176 5.2E-39 T 29-03-2018 CSW12_RS30580 8469246e12ca527fb035685ae7a66bef 998 Pfam PF01526 Tn3 transposase DDE domain 593 983 1.1E-130 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 CSW12_RS30580 8469246e12ca527fb035685ae7a66bef 998 Pfam PF13700 Domain of unknown function (DUF4158) 2 157 1.6E-29 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS02490 f6a36cf24ef1a7442a569ae419fe95f2 118 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 21 106 1.7E-5 T 29-03-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor CSW12_RS12365 93da95744dc3ff67843508cd0ef23cd0 240 Pfam PF17294 Uncharacterised lipoprotein family 32 239 5.2E-38 T 29-03-2018 IPR035253 Putative lipoprotein, bacteria CSW12_RS15455 f38b2bf82e4b8f153ee29f5e34e91bef 471 Pfam PF13520 Amino acid permease 26 441 6.4E-61 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS15455 f38b2bf82e4b8f153ee29f5e34e91bef 471 PIRSF PIRSF006060 5 469 1.4E-90 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS10830 3d0b566747bfd5ce7d78627ba9e8af39 118 Pfam PF13471 Transglutaminase-like superfamily 29 107 4.7E-13 T 29-03-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal CSW12_RS23720 f038af56da3f84c54f8b4802482fa47c 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 1.2E-21 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CSW12_RS09695 8b7dcad02eee0cab098694a476039ff2 315 Gene3D G3DSA:3.30.420.10 8 186 1.5E-44 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS09695 8b7dcad02eee0cab098694a476039ff2 315 Pfam PF00929 Exonuclease 11 165 1.8E-35 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS09695 8b7dcad02eee0cab098694a476039ff2 315 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 10 178 3.0E-30 T 29-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CSW12_RS09695 8b7dcad02eee0cab098694a476039ff2 315 SMART SM00479 9 174 2.7E-50 T 29-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CSW12_RS09695 8b7dcad02eee0cab098694a476039ff2 315 SUPERFAMILY SSF53098 7 197 9.72E-56 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS25590 0219686f092bd7fa0531a0f495f96026 103 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.046 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS25590 0219686f092bd7fa0531a0f495f96026 103 SUPERFAMILY SSF117782 1 103 7.19E-36 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS25590 0219686f092bd7fa0531a0f495f96026 103 Pfam PF01906 Putative heavy-metal-binding 1 103 6.5E-37 T 29-03-2018 IPR002765 Uncharacterised protein family UPF0145 CSW12_RS25590 0219686f092bd7fa0531a0f495f96026 103 Gene3D G3DSA:3.30.110.70 1 103 6.8E-34 T 29-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CSW12_RS16685 11c23f8a331d039da780bb0ce4186996 650 Gene3D G3DSA:3.40.50.300 284 487 2.4E-15 T 29-03-2018 CSW12_RS16685 11c23f8a331d039da780bb0ce4186996 650 Pfam PF07728 AAA domain (dynein-related subfamily) 320 465 1.2E-4 T 29-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CSW12_RS16685 11c23f8a331d039da780bb0ce4186996 650 SUPERFAMILY SSF52540 314 495 1.32E-11 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS21335 1c2a96e455e40b0eda5caa68888cb792 497 Pfam PF16244 Domain of unknown function (DUF4901) 11 239 1.3E-106 T 29-03-2018 IPR032599 Protein of unknown function DUF4901 CSW12_RS10545 1048cf350e0d0e7e154b961e4f828133 162 Gene3D G3DSA:1.20.120.450 3 162 3.3E-19 T 29-03-2018 CSW12_RS10545 1048cf350e0d0e7e154b961e4f828133 162 Pfam PF05163 DinB family 7 161 2.2E-22 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CSW12_RS10545 1048cf350e0d0e7e154b961e4f828133 162 SUPERFAMILY SSF109854 1 160 4.03E-30 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS02970 2d5361d849fa7b4f4fff6f0a9832ca6a 206 Pfam PF02581 Thiamine monophosphate synthase 10 181 1.5E-39 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS02970 2d5361d849fa7b4f4fff6f0a9832ca6a 206 SUPERFAMILY SSF51391 8 199 1.83E-43 T 29-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CSW12_RS02970 2d5361d849fa7b4f4fff6f0a9832ca6a 206 Gene3D G3DSA:3.20.20.70 3 206 6.4E-32 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS00275 c1dbd3b5d34bab3b92ec00a4624ae7a8 143 Pfam PF05119 Phage terminase, small subunit 22 120 1.2E-12 T 29-03-2018 IPR006448 Putative phage terminase, small subunit, P27 family CSW12_RS05290 3940031eb0fae7298486113255983009 413 SUPERFAMILY SSF51011 301 382 3.14E-11 T 29-03-2018 CSW12_RS05290 3940031eb0fae7298486113255983009 413 Gene3D G3DSA:3.20.20.80 5 121 1.8E-34 T 29-03-2018 CSW12_RS05290 3940031eb0fae7298486113255983009 413 Gene3D G3DSA:3.20.20.80 123 296 3.9E-17 T 29-03-2018 CSW12_RS05290 3940031eb0fae7298486113255983009 413 SUPERFAMILY SSF51445 12 301 7.87E-50 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS05290 3940031eb0fae7298486113255983009 413 Pfam PF00128 Alpha amylase, catalytic domain 50 118 2.9E-24 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS05290 3940031eb0fae7298486113255983009 413 Pfam PF00128 Alpha amylase, catalytic domain 163 265 6.5E-8 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS05290 3940031eb0fae7298486113255983009 413 Gene3D G3DSA:2.60.40.1180 297 384 5.7E-19 T 29-03-2018 CSW12_RS05290 3940031eb0fae7298486113255983009 413 SMART SM00642 22 292 7.0E-11 T 29-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CSW12_RS25780 2edd3021393d48856eb3b04ddaf5d5d8 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 8.5E-23 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS25780 2edd3021393d48856eb3b04ddaf5d5d8 100 SUPERFAMILY SSF52794 1 99 4.45E-35 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS25780 2edd3021393d48856eb3b04ddaf5d5d8 100 Gene3D G3DSA:3.40.50.2300 1 100 3.3E-37 T 29-03-2018 CSW12_RS12070 a2d04e40c1f10703d9827dba85bc668d 153 Pfam PF03073 TspO/MBR family 11 150 5.8E-31 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CSW12_RS12070 a2d04e40c1f10703d9827dba85bc668d 153 PIRSF PIRSF005859 1 153 2.5E-41 T 29-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CSW12_RS13760 0b28ca01d4d7f80785226f17abf8e383 276 Gene3D G3DSA:3.60.40.10 36 261 2.8E-15 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS13760 0b28ca01d4d7f80785226f17abf8e383 276 SUPERFAMILY SSF81606 45 256 3.53E-13 T 29-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CSW12_RS13760 0b28ca01d4d7f80785226f17abf8e383 276 Pfam PF13672 Protein phosphatase 2C 43 240 1.2E-19 T 29-03-2018 CSW12_RS14080 e91c4849c4f748ebb11057ddabb8ee39 101 Pfam PF12867 DinB superfamily 28 86 2.1E-7 T 29-03-2018 IPR024775 DinB-like domain CSW12_RS14080 e91c4849c4f748ebb11057ddabb8ee39 101 SUPERFAMILY SSF109854 17 90 6.41E-14 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS14080 e91c4849c4f748ebb11057ddabb8ee39 101 Gene3D G3DSA:1.20.120.450 5 94 1.2E-7 T 29-03-2018 CSW12_RS22320 fd27c6807d593e326528e1b3d68f9dee 254 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 11 246 1.0E-99 T 29-03-2018 IPR009835 Sortase B family CSW12_RS22320 fd27c6807d593e326528e1b3d68f9dee 254 Gene3D G3DSA:2.40.260.10 66 251 2.6E-65 T 29-03-2018 IPR023365 Sortase domain CSW12_RS22320 fd27c6807d593e326528e1b3d68f9dee 254 Pfam PF04203 Sortase family 85 251 3.1E-23 T 29-03-2018 IPR005754 Sortase family CSW12_RS22320 fd27c6807d593e326528e1b3d68f9dee 254 SUPERFAMILY SSF63817 21 253 4.71E-89 T 29-03-2018 IPR023365 Sortase domain CSW12_RS22320 fd27c6807d593e326528e1b3d68f9dee 254 PIRSF PIRSF030150 7 252 2.3E-104 T 29-03-2018 IPR015986 Sortase B, Firmicutes CSW12_RS10575 85ac8fa464128171703030e8a365243c 302 Gene3D G3DSA:3.40.50.1980 37 145 1.2E-16 T 29-03-2018 CSW12_RS10575 85ac8fa464128171703030e8a365243c 302 Gene3D G3DSA:3.40.50.1980 146 302 1.8E-28 T 29-03-2018 CSW12_RS10575 85ac8fa464128171703030e8a365243c 302 SUPERFAMILY SSF53807 40 300 6.28E-48 T 29-03-2018 CSW12_RS10575 85ac8fa464128171703030e8a365243c 302 Pfam PF01497 Periplasmic binding protein 51 279 2.4E-30 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 Gene3D G3DSA:1.10.3100.10 2 151 9.8E-18 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 SMART SM00530 12 67 8.9E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 SUPERFAMILY SSF47413 7 72 1.26E-14 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 SUPERFAMILY SSF51306 132 254 3.31E-20 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 Gene3D G3DSA:2.10.109.10 152 259 1.5E-14 T 29-03-2018 CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 Pfam PF01381 Helix-turn-helix 13 65 5.1E-14 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS05055 545fb082aac90fec9415615c6b13566e 261 Pfam PF00717 Peptidase S24-like 172 224 2.3E-6 T 29-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CSW12_RS11760 8cb388efc8ba52e0d45ca693108982a4 197 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 44 1.7E-12 T 29-03-2018 IPR023833 Signal peptide, camelysin CSW12_RS11760 8cb388efc8ba52e0d45ca693108982a4 197 Pfam PF12389 Camelysin metallo-endopeptidase 2 196 9.9E-89 T 29-03-2018 IPR022121 Peptidase M73, camelysin CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.0E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.0E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.0E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.0E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.0E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.0E-40 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 43.783 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 Pfam PF00318 Ribosomal protein S2 9 224 3.9E-102 T 29-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 29-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 SUPERFAMILY SSF52313 6 227 3.66E-100 T 29-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 Gene3D G3DSA:3.40.50.10490 5 233 3.6E-103 T 29-03-2018 CSW12_RS08640 3da42f77a941a2e1b2ff08736aec3b60 233 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.8E-113 T 29-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS07305 8db145a7de6970741cc54bf3a0e68c2f 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 136 1.3E-70 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CSW12_RS07305 8db145a7de6970741cc54bf3a0e68c2f 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 34.938 T 29-03-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0030435|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CSW12_RS07305 8db145a7de6970741cc54bf3a0e68c2f 146 SUPERFAMILY SSF55874 28 135 1.7E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07305 8db145a7de6970741cc54bf3a0e68c2f 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 1.9E-22 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07305 8db145a7de6970741cc54bf3a0e68c2f 146 Gene3D G3DSA:3.30.565.10 1 144 1.5E-18 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS07305 8db145a7de6970741cc54bf3a0e68c2f 146 SMART SM00387 35 140 2.1E-6 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS20910 0b9bfc5a04ca0bd8c6be99e998c7df00 370 SUPERFAMILY SSF53335 17 361 1.74E-80 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS20910 0b9bfc5a04ca0bd8c6be99e998c7df00 370 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 79 294 3.6E-43 T 29-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CSW12_RS22050 2b6f19ad8a0d6e394c4610d0832880ff 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 7.2E-32 T 29-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CSW12_RS22050 2b6f19ad8a0d6e394c4610d0832880ff 167 SUPERFAMILY SSF56300 1 162 3.21E-44 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS22050 2b6f19ad8a0d6e394c4610d0832880ff 167 Gene3D G3DSA:3.60.21.10 1 154 7.1E-22 T 29-03-2018 IPR029052 Metallo-dependent phosphatase-like CSW12_RS22050 2b6f19ad8a0d6e394c4610d0832880ff 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 148 3.2E-31 T 29-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CSW12_RS25585 d8826b34e5311be4c5730094ec9efb7f 119 SUPERFAMILY SSF52540 2 61 3.52E-8 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS25585 d8826b34e5311be4c5730094ec9efb7f 119 Gene3D G3DSA:3.40.50.300 1 118 2.7E-12 T 29-03-2018 CSW12_RS21915 880808e6e665d546042aa73b0e254abc 316 Gene3D G3DSA:3.40.30.10 146 304 7.6E-4 T 29-03-2018 CSW12_RS17635 1f3f700393564ad0d550500d1d360308 72 Gene3D G3DSA:3.40.190.10 10 71 1.4E-4 T 29-03-2018 CSW12_RS23545 d82d71b0eeac18b1f4dd744bffec2b45 301 Pfam PF00892 EamA-like transporter family 153 284 1.3E-18 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS23545 d82d71b0eeac18b1f4dd744bffec2b45 301 Pfam PF00892 EamA-like transporter family 7 138 3.8E-28 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS23545 d82d71b0eeac18b1f4dd744bffec2b45 301 SUPERFAMILY SSF103481 39 142 4.45E-17 T 29-03-2018 CSW12_RS23545 d82d71b0eeac18b1f4dd744bffec2b45 301 SUPERFAMILY SSF103481 201 286 9.15E-13 T 29-03-2018 CSW12_RS19520 fc349c3daacc56b79f838546fb616d62 387 Gene3D G3DSA:1.20.91.10 227 308 5.4E-18 T 29-03-2018 CSW12_RS19520 fc349c3daacc56b79f838546fb616d62 387 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 281 2.6E-78 T 29-03-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CSW12_RS19520 fc349c3daacc56b79f838546fb616d62 387 Pfam PF00999 Sodium/hydrogen exchanger family 10 373 5.8E-76 T 29-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CSW12_RS06105 da856972a6fd5e9856d63a90a1ce4259 174 Pfam PF09602 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 1 164 1.5E-66 T 29-03-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP CSW12_RS06105 da856972a6fd5e9856d63a90a1ce4259 174 TIGRFAM TIGR02131 phaP_Bmeg: polyhydroxyalkanoic acid inclusion protein PhaP 1 164 1.1E-84 T 29-03-2018 IPR011728 Polyhydroxyalkanoic acid inclusion protein PhaP CSW12_RS06105 da856972a6fd5e9856d63a90a1ce4259 174 Gene3D G3DSA:1.20.1170.10 14 106 1.2E-4 T 29-03-2018 CSW12_RS26680 57773ce97b8ed5af75a5916c645268c2 312 Pfam PF01497 Periplasmic binding protein 95 286 4.1E-33 T 29-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CSW12_RS26680 57773ce97b8ed5af75a5916c645268c2 312 SUPERFAMILY SSF53807 36 288 3.18E-56 T 29-03-2018 CSW12_RS26680 57773ce97b8ed5af75a5916c645268c2 312 Gene3D G3DSA:3.40.50.1980 151 310 3.1E-29 T 29-03-2018 CSW12_RS26680 57773ce97b8ed5af75a5916c645268c2 312 Gene3D G3DSA:3.40.50.1980 25 150 7.7E-28 T 29-03-2018 CSW12_RS17655 7cc679203030c9d8b97085d4b1c52308 171 Pfam PF03061 Thioesterase superfamily 31 103 1.5E-12 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS17655 7cc679203030c9d8b97085d4b1c52308 171 SUPERFAMILY SSF54637 11 159 3.38E-43 T 29-03-2018 IPR029069 HotDog domain CSW12_RS17655 7cc679203030c9d8b97085d4b1c52308 171 Gene3D G3DSA:3.10.129.10 3 162 3.9E-44 T 29-03-2018 CSW12_RS10625 e2d443e5678efb61991e0f7ef64d1ff7 74 Gene3D G3DSA:1.20.5.50 1 59 5.3E-4 T 29-03-2018 CSW12_RS10625 e2d443e5678efb61991e0f7ef64d1ff7 74 Pfam PF10779 Haemolysin XhlA 6 69 9.4E-11 T 29-03-2018 IPR019715 Haemolysin XhlA CSW12_RS26060 61167514a9d28e96124fe091edc7e4ab 344 Pfam PF13343 Bacterial extracellular solute-binding protein 88 329 4.5E-50 T 29-03-2018 CSW12_RS26060 61167514a9d28e96124fe091edc7e4ab 344 SUPERFAMILY SSF53850 42 307 5.55E-49 T 29-03-2018 CSW12_RS26060 61167514a9d28e96124fe091edc7e4ab 344 Gene3D G3DSA:3.40.190.10 138 307 4.5E-22 T 29-03-2018 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 380 36.456 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 Gene3D G3DSA:3.30.420.40 1 194 9.6E-57 T 29-03-2018 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 Gene3D G3DSA:3.30.420.40 227 383 3.4E-20 T 29-03-2018 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 378 3.3E-97 T 29-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 SUPERFAMILY SSF53067 1 40 9.06E-18 T 29-03-2018 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 SUPERFAMILY SSF53067 67 112 9.06E-18 T 29-03-2018 CSW12_RS15740 54c45e57a38eadce870a37de2051c67d 384 SUPERFAMILY SSF53067 147 340 9.06E-18 T 29-03-2018 CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 Pfam PF07690 Major Facilitator Superfamily 20 411 1.3E-52 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 Gene3D G3DSA:1.20.1250.20 254 512 6.7E-31 T 29-03-2018 CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 17 490 7.1E-79 T 29-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 Gene3D G3DSA:1.20.1250.20 13 203 2.3E-35 T 29-03-2018 CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 SUPERFAMILY SSF103473 471 498 7.46E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 SUPERFAMILY SSF103473 251 421 7.46E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS07730 c6673a8e1306a8a64396571d935242e1 513 SUPERFAMILY SSF103473 11 204 7.46E-75 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS14170 d2405979f32b4450e9563a4423c0280c 126 PIRSF PIRSF026568 1 126 1.5E-82 T 29-03-2018 IPR014527 Excinuclease GIY-YIG catalytic domain-containing uncharacterised conserved protein CSW12_RS14170 d2405979f32b4450e9563a4423c0280c 126 Pfam PF01541 GIY-YIG catalytic domain 45 119 3.0E-12 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS14170 d2405979f32b4450e9563a4423c0280c 126 SUPERFAMILY SSF82771 44 122 1.57E-13 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS14170 d2405979f32b4450e9563a4423c0280c 126 Gene3D G3DSA:3.40.1440.10 39 126 8.2E-16 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS14170 d2405979f32b4450e9563a4423c0280c 126 SMART SM00465 45 124 7.0E-15 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 Gene3D G3DSA:2.30.40.10 457 522 3.7E-10 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 SUPERFAMILY SSF51338 477 519 2.99E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 SUPERFAMILY SSF51338 4 59 2.99E-16 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 Pfam PF07969 Amidohydrolase family 50 518 5.4E-134 T 29-03-2018 IPR013108 Amidohydrolase 3 CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 Gene3D G3DSA:2.30.40.10 2 70 2.9E-17 T 29-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 Gene3D G3DSA:3.20.20.140 71 456 5.1E-38 T 29-03-2018 CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 SUPERFAMILY SSF51556 58 119 3.14E-35 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS22850 86b263691e3fc743350be2a04d3ed459 522 SUPERFAMILY SSF51556 195 477 3.14E-35 T 29-03-2018 IPR032466 Metal-dependent hydrolase CSW12_RS20560 4daa8dba4209a9aeac1237736ae5398c 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 89 2.0E-36 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV CSW12_RS20560 4daa8dba4209a9aeac1237736ae5398c 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 9.0E-28 T 29-03-2018 IPR020390 Uncharacterised protein family YqhV CSW12_RS00875 d6e1ac69959b0b3044d808f82fb735b8 103 Pfam PF14150 YesK-like protein 16 96 4.3E-32 T 29-03-2018 IPR025434 YesK-like protein CSW12_RS06630 e45e55dfcf49b9ed968581e1f707567e 252 SUPERFAMILY SSF51366 1 251 2.83E-81 T 29-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CSW12_RS06630 e45e55dfcf49b9ed968581e1f707567e 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.996 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CSW12_RS06630 e45e55dfcf49b9ed968581e1f707567e 252 Pfam PF00977 Histidine biosynthesis protein 5 234 7.5E-91 T 29-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CSW12_RS06630 e45e55dfcf49b9ed968581e1f707567e 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 1.8E-114 T 29-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CSW12_RS06630 e45e55dfcf49b9ed968581e1f707567e 252 Gene3D G3DSA:3.20.20.70 4 247 5.4E-69 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS17705 38fd4728925f75135fc6beaca415a40a 181 SUPERFAMILY SSF51735 3 158 2.13E-8 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS17705 38fd4728925f75135fc6beaca415a40a 181 Gene3D G3DSA:3.40.50.720 2 124 1.8E-7 T 29-03-2018 CSW12_RS10435 167371d4c46fa5658e22b027441151e3 395 Gene3D G3DSA:1.20.1250.20 200 395 1.5E-19 T 29-03-2018 CSW12_RS10435 167371d4c46fa5658e22b027441151e3 395 SUPERFAMILY SSF103473 4 394 1.22E-59 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS10435 167371d4c46fa5658e22b027441151e3 395 Gene3D G3DSA:1.20.1250.20 2 199 1.6E-29 T 29-03-2018 CSW12_RS10435 167371d4c46fa5658e22b027441151e3 395 Pfam PF07690 Major Facilitator Superfamily 20 359 4.9E-36 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS05750 b7b634b8e5ab3961f0b86cb9bba39b7b 119 Pfam PF13221 Protein of unknown function (DUF4029) 22 117 4.4E-57 T 29-03-2018 IPR025107 Protein of unknown function DUF4029 CSW12_RS28065 fa26a9fcf000bb97cd454396de6e4d85 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.6E-49 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28065 fa26a9fcf000bb97cd454396de6e4d85 120 SUPERFAMILY SSF53137 7 118 3.49E-56 T 29-03-2018 CSW12_RS28065 fa26a9fcf000bb97cd454396de6e4d85 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 6.8E-53 T 29-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS28065 fa26a9fcf000bb97cd454396de6e4d85 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.937 T 29-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS28065 fa26a9fcf000bb97cd454396de6e4d85 120 Gene3D G3DSA:3.30.420.100 1 120 5.2E-46 T 29-03-2018 CSW12_RS19970 f9e66cb6f58b446c33c0518380fd42e9 228 Pfam PF07314 Protein of unknown function (DUF1461) 18 190 4.4E-45 T 29-03-2018 IPR010178 Integral membrane protein 1906 CSW12_RS19970 f9e66cb6f58b446c33c0518380fd42e9 228 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 16 213 6.8E-41 T 29-03-2018 IPR010178 Integral membrane protein 1906 CSW12_RS06270 5457be7c0d3c472dadb37591557995b5 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 3 57 3.2E-25 T 29-03-2018 IPR018690 Protein of unknown function DUF2187 CSW12_RS04080 4c5f5ab7c759381388e96d09c9057ca6 184 Pfam PF04982 HPP family 64 180 5.0E-43 T 29-03-2018 IPR007065 HPP CSW12_RS06750 d261703c075edaa09fcf29107a0ace1f 172 Pfam PF04167 Protein of unknown function (DUF402) 57 125 1.3E-16 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS06750 d261703c075edaa09fcf29107a0ace1f 172 Gene3D G3DSA:2.40.380.10 51 166 5.9E-27 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS06750 d261703c075edaa09fcf29107a0ace1f 172 SUPERFAMILY SSF159234 1 166 4.58E-40 T 29-03-2018 IPR007295 Domain of unknown function DUF402 CSW12_RS19145 ccb6d78ae029f60620f077fa2451262a 174 SUPERFAMILY SSF48452 20 95 6.42E-5 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS19145 ccb6d78ae029f60620f077fa2451262a 174 Gene3D G3DSA:3.40.1030.10 11 172 8.7E-5 T 29-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CSW12_RS19145 ccb6d78ae029f60620f077fa2451262a 174 Pfam PF14346 Domain of unknown function (DUF4398) 12 119 2.2E-16 T 29-03-2018 IPR025511 Domain of unknown function DUF4398 CSW12_RS03565 9892246c746f398f98155b2dd2cf5b6b 474 Pfam PF13520 Amino acid permease 7 430 4.8E-54 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS03565 9892246c746f398f98155b2dd2cf5b6b 474 PIRSF PIRSF006060 1 473 3.9E-56 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS09005 3f99068e2838a322cc4913b7b3759e1e 118 Pfam PF03788 LrgA family 18 109 5.0E-23 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CSW12_RS09005 3f99068e2838a322cc4913b7b3759e1e 118 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 118 22.746 T 29-03-2018 IPR023760 Holin-like protein CidA GO:0016021 CSW12_RS21705 38681ae87e8bf35c1045999744d003ec 519 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 359 500 3.8E-17 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CSW12_RS21705 38681ae87e8bf35c1045999744d003ec 519 PIRSF PIRSF038958 1 517 4.7E-175 T 29-03-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type CSW12_RS21705 38681ae87e8bf35c1045999744d003ec 519 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 1.1E-53 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS21705 38681ae87e8bf35c1045999744d003ec 519 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 494 2.8E-197 T 29-03-2018 IPR014249 Sporulation stage V protein B CSW12_RS17915 290d91d7bde8512a796fc7004e11711b 204 Pfam PF01810 LysE type translocator 15 198 5.1E-29 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS05125 c157348949aa1a199bc857bf19116beb 131 Gene3D G3DSA:1.10.10.10 81 129 6.3E-9 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS05125 c157348949aa1a199bc857bf19116beb 131 Pfam PF04545 Sigma-70, region 4 83 123 4.9E-6 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS05125 c157348949aa1a199bc857bf19116beb 131 SUPERFAMILY SSF88659 62 123 2.62E-10 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS05125 c157348949aa1a199bc857bf19116beb 131 Gene3D G3DSA:1.20.5.110 10 80 0.004 T 29-03-2018 CSW12_RS14545 7751aabba5545f786d179c43a446a54f 395 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 391 8.1E-93 T 29-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CSW12_RS14545 7751aabba5545f786d179c43a446a54f 395 Gene3D G3DSA:3.40.50.2000 227 375 7.2E-32 T 29-03-2018 CSW12_RS14545 7751aabba5545f786d179c43a446a54f 395 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 272 369 1.2E-14 T 29-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CSW12_RS14545 7751aabba5545f786d179c43a446a54f 395 Gene3D G3DSA:3.40.50.2000 2 226 3.4E-27 T 29-03-2018 CSW12_RS14545 7751aabba5545f786d179c43a446a54f 395 SUPERFAMILY SSF53756 3 390 1.07E-75 T 29-03-2018 CSW12_RS04165 317b9f1f31541cfbd57b11da9b2f5cc4 116 Gene3D G3DSA:2.30.30.410 21 115 2.7E-10 T 29-03-2018 CSW12_RS04165 317b9f1f31541cfbd57b11da9b2f5cc4 116 Pfam PF08239 Bacterial SH3 domain 51 111 2.7E-7 T 29-03-2018 IPR003646 SH3-like domain, bacterial-type CSW12_RS17975 a099796005f6d72ca92d2cdb6c468196 273 Pfam PF01522 Polysaccharide deacetylase 64 173 9.7E-29 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS17975 a099796005f6d72ca92d2cdb6c468196 273 Gene3D G3DSA:3.20.20.370 28 259 3.0E-48 T 29-03-2018 CSW12_RS17975 a099796005f6d72ca92d2cdb6c468196 273 SUPERFAMILY SSF88713 63 260 2.72E-55 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS07740 23e6b69a446e92575eaf283ef0184a1a 77 Pfam PF04688 SPP1 phage holin 2 74 4.5E-18 T 29-03-2018 IPR006479 Holin CSW12_RS09475 0d78c089d69b4f06d65952e654fcf7fd 190 SUPERFAMILY SSF52317 1 163 3.55E-33 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS09475 0d78c089d69b4f06d65952e654fcf7fd 190 Pfam PF01965 DJ-1/PfpI family 2 155 8.0E-29 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS09475 0d78c089d69b4f06d65952e654fcf7fd 190 Gene3D G3DSA:3.40.50.880 1 161 4.3E-27 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS12830 d6b916e981a5b5d52a53403f8f3015f6 348 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 9 340 3.2E-113 T 29-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CSW12_RS12830 d6b916e981a5b5d52a53403f8f3015f6 348 PIRSF PIRSF012608 1 348 1.8E-143 T 29-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 209 7.0E-58 T 29-03-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 20 127 5.3E-20 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 142 206 2.7E-19 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 SMART SM00983 141 207 1.3E-25 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 SUPERFAMILY SSF63862 133 211 3.27E-16 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 Gene3D G3DSA:3.40.50.10240 1 118 7.0E-23 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 SUPERFAMILY SSF63999 3 130 1.24E-32 T 29-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS08475 5443b9fc0b0bc506502f19bc784b17ab 213 Gene3D G3DSA:2.60.120.320 119 213 5.3E-22 T 29-03-2018 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CSW12_RS18375 9b3fbefa5389c132e4a03bb894e0a167 315 Gene3D G3DSA:1.10.10.60 1 52 3.1E-18 T 29-03-2018 CSW12_RS18375 9b3fbefa5389c132e4a03bb894e0a167 315 SUPERFAMILY SSF88659 11 47 1.9E-7 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18375 9b3fbefa5389c132e4a03bb894e0a167 315 Pfam PF04545 Sigma-70, region 4 14 47 1.4E-6 T 29-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS18375 9b3fbefa5389c132e4a03bb894e0a167 315 SUPERFAMILY SSF100950 56 312 8.84E-75 T 29-03-2018 CSW12_RS18375 9b3fbefa5389c132e4a03bb894e0a167 315 Gene3D G3DSA:3.40.50.1360 53 315 8.5E-45 T 29-03-2018 CSW12_RS18375 9b3fbefa5389c132e4a03bb894e0a167 315 Pfam PF04198 Putative sugar-binding domain 57 310 2.9E-77 T 29-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CSW12_RS07545 fa2293e53453ec95d3403cb583372aa3 255 Gene3D G3DSA:1.10.1900.10 1 67 2.1E-15 T 29-03-2018 CSW12_RS07545 fa2293e53453ec95d3403cb583372aa3 255 SUPERFAMILY SSF158560 1 86 2.75E-18 T 29-03-2018 CSW12_RS07610 44fa044b860b8d5256b48f672e1f04cb 403 Gene3D G3DSA:1.20.1250.20 201 392 1.7E-15 T 29-03-2018 CSW12_RS07610 44fa044b860b8d5256b48f672e1f04cb 403 Gene3D G3DSA:1.20.1250.20 8 200 5.9E-25 T 29-03-2018 CSW12_RS07610 44fa044b860b8d5256b48f672e1f04cb 403 Pfam PF07690 Major Facilitator Superfamily 16 266 2.7E-19 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS07610 44fa044b860b8d5256b48f672e1f04cb 403 SUPERFAMILY SSF103473 5 393 3.01E-49 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS04500 80beb3c9b5dc6169719f4a1f908fa989 81 Gene3D G3DSA:3.30.40.10 4 78 3.9E-4 T 29-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type CSW12_RS04090 329f8572e762c0847c132bfbb0f4e82e 152 Gene3D G3DSA:1.10.10.10 1 148 7.6E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04090 329f8572e762c0847c132bfbb0f4e82e 152 SUPERFAMILY SSF46785 4 139 7.65E-24 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS04090 329f8572e762c0847c132bfbb0f4e82e 152 Pfam PF12802 MarR family 32 90 1.4E-10 T 29-03-2018 CSW12_RS04090 329f8572e762c0847c132bfbb0f4e82e 152 SMART SM00347 26 126 1.5E-10 T 29-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CSW12_RS16420 e3f53c3d482f3e039b53ca29c5ef5e76 104 Pfam PF00085 Thioredoxin 5 102 4.4E-18 T 29-03-2018 IPR013766 Thioredoxin domain GO:0045454 CSW12_RS16420 e3f53c3d482f3e039b53ca29c5ef5e76 104 Gene3D G3DSA:3.40.30.10 1 104 1.6E-25 T 29-03-2018 CSW12_RS16420 e3f53c3d482f3e039b53ca29c5ef5e76 104 SUPERFAMILY SSF52833 2 103 2.76E-27 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS09285 c55011e2782cd3b0b7fc937961986906 180 Pfam PF08006 Protein of unknown function (DUF1700) 1 179 4.1E-72 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 CSW12_RS16300 77287df98cdaa914c5bb909db8e30d10 381 Pfam PF07690 Major Facilitator Superfamily 13 281 1.0E-39 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS16300 77287df98cdaa914c5bb909db8e30d10 381 SUPERFAMILY SSF103473 7 377 2.22E-64 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS16300 77287df98cdaa914c5bb909db8e30d10 381 Gene3D G3DSA:1.20.1250.20 196 379 1.3E-26 T 29-03-2018 CSW12_RS16300 77287df98cdaa914c5bb909db8e30d10 381 Gene3D G3DSA:1.20.1250.20 1 195 2.4E-32 T 29-03-2018 CSW12_RS16300 77287df98cdaa914c5bb909db8e30d10 381 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 29-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CSW12_RS02610 ecc452a75ec45ea9d192a417e3921e8e 270 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 5 270 17.237 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS02610 ecc452a75ec45ea9d192a417e3921e8e 270 Pfam PF02673 Bacitracin resistance protein BacA 11 265 1.0E-75 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS06350 f7886b1434c0b26c5b8ec87d35537f90 258 Pfam PF12730 ABC-2 family transporter protein 4 182 1.9E-36 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CSW12_RS25285 e9bac3e3b988bc8ac22d2a404ae0aa2d 338 SUPERFAMILY SSF81345 17 330 8.63E-66 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS25285 e9bac3e3b988bc8ac22d2a404ae0aa2d 338 Pfam PF01032 FecCD transport family 36 330 1.5E-66 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS25285 e9bac3e3b988bc8ac22d2a404ae0aa2d 338 Gene3D G3DSA:1.10.3470.10 14 333 1.7E-44 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS04125 192cd54930e2a79ea9cecb04408a51ac 211 Pfam PF04892 VanZ like family 43 161 2.2E-22 T 29-03-2018 IPR006976 VanZ-like CSW12_RS15805 6adc63d9777702c7b8e12558bf6fca6c 210 Pfam PF00190 Cupin 32 132 2.3E-10 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CSW12_RS15805 6adc63d9777702c7b8e12558bf6fca6c 210 SUPERFAMILY SSF51182 30 173 6.58E-27 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS15805 6adc63d9777702c7b8e12558bf6fca6c 210 SMART SM00835 21 158 2.0E-14 T 29-03-2018 IPR006045 Cupin 1 GO:0045735 CSW12_RS15805 6adc63d9777702c7b8e12558bf6fca6c 210 Gene3D G3DSA:2.60.120.10 10 184 3.7E-20 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS02960 7e7de748f67782ba370656ccf7e20fe7 250 SUPERFAMILY SSF161098 54 231 4.97E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS02960 7e7de748f67782ba370656ccf7e20fe7 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 243 1.8E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS02960 7e7de748f67782ba370656ccf7e20fe7 250 Gene3D G3DSA:1.10.3720.10 10 249 8.0E-26 T 29-03-2018 CSW12_RS03945 7d8ef09e0a85205a49acc496fd24fc8c 248 Gene3D G3DSA:1.10.601.10 27 213 1.5E-5 T 29-03-2018 CSW12_RS18250 6559dfbbe4c343887d3b5e0449aa09fb 200 SUPERFAMILY SSF55469 7 200 2.75E-65 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS18250 6559dfbbe4c343887d3b5e0449aa09fb 200 Pfam PF00881 Nitroreductase family 12 179 3.9E-22 T 29-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CSW12_RS18250 6559dfbbe4c343887d3b5e0449aa09fb 200 Gene3D G3DSA:3.40.109.10 6 200 5.0E-34 T 29-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CSW12_RS23820 fff8a1a7b61dc2ed1ada62130e0dbd0e 175 Pfam PF00156 Phosphoribosyl transferase domain 13 158 1.9E-24 T 29-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CSW12_RS23820 fff8a1a7b61dc2ed1ada62130e0dbd0e 175 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 172 4.9E-64 T 29-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CSW12_RS23820 fff8a1a7b61dc2ed1ada62130e0dbd0e 175 Gene3D G3DSA:3.40.50.2020 1 175 1.8E-42 T 29-03-2018 CSW12_RS23820 fff8a1a7b61dc2ed1ada62130e0dbd0e 175 SUPERFAMILY SSF53271 4 174 2.15E-53 T 29-03-2018 IPR029057 Phosphoribosyltransferase-like CSW12_RS25940 e18b6d186159dd93bb766e39e4d40948 433 SUPERFAMILY SSF53448 64 340 8.44E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS25940 e18b6d186159dd93bb766e39e4d40948 433 Gene3D G3DSA:3.90.550.10 54 324 1.3E-53 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS25940 e18b6d186159dd93bb766e39e4d40948 433 Pfam PF13641 Glycosyltransferase like family 2 69 294 1.3E-33 T 29-03-2018 CSW12_RS25880 5c460ca89868e6c7425fc8103e2e81aa 553 Pfam PF02652 L-lactate permease 17 543 3.3E-214 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CSW12_RS25880 5c460ca89868e6c7425fc8103e2e81aa 553 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 546 5.2E-224 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CSW12_RS30210 8de4dffac3eb65cf94ea4fe8e6ecf44f 473 SUPERFAMILY SSF53098 31 467 1.44E-65 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS30210 8de4dffac3eb65cf94ea4fe8e6ecf44f 473 Gene3D G3DSA:3.90.350.10 184 367 1.2E-20 T 29-03-2018 IPR014736 Transposase, Tn5-like, core CSW12_RS30210 8de4dffac3eb65cf94ea4fe8e6ecf44f 473 Pfam PF01609 Transposase DDE domain 120 386 1.4E-42 T 29-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CSW12_RS09970 3b5f51f3018c00f9a3247df34d7e8ca4 141 Pfam PF02681 Divergent PAP2 family 6 135 5.6E-50 T 29-03-2018 IPR003832 Acid phosphatase/vanadium-dependent haloperoxidase-related CSW12_RS09970 3b5f51f3018c00f9a3247df34d7e8ca4 141 Gene3D G3DSA:1.20.144.10 9 141 4.6E-9 T 29-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CSW12_RS02535 c8144d692d89c9e1994760c6117ee6aa 391 Pfam PF10651 Domain of unknown function (DUF2479) 14 137 6.5E-17 T 29-03-2018 IPR018913 Domain of unknown function DUF2479 CSW12_RS17995 eec8837b4a740c2d9cfcd6620c7148de 335 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 99 247 1.8E-37 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS17995 eec8837b4a740c2d9cfcd6620c7148de 335 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 99 246 1.2E-42 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 196 207 - T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 Pfam PF02926 THUMP domain 20 154 1.7E-16 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 SMART SM00981 57 155 2.5E-8 T 29-03-2018 IPR004114 THUMP domain GO:0003723 CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 Pfam PF01170 Putative RNA methylase family UPF0020 163 367 4.6E-65 T 29-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 SUPERFAMILY SSF53335 255 361 4.22E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 SUPERFAMILY SSF53335 144 218 4.22E-39 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 29-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CSW12_RS19785 cb76c82b4dfe59bc7810feca34c2fa19 379 Gene3D G3DSA:3.40.50.150 161 378 6.4E-36 T 29-03-2018 CSW12_RS30665 7beec994def5b42b791e1dcb8c75f5b6 61 SUPERFAMILY SSF160059 1 47 6.15E-19 T 29-03-2018 CSW12_RS30665 7beec994def5b42b791e1dcb8c75f5b6 61 Gene3D G3DSA:3.40.5.20 1 45 5.8E-21 T 29-03-2018 IPR027926 Uncharacterised protein YqbF domain CSW12_RS30665 7beec994def5b42b791e1dcb8c75f5b6 61 Pfam PF14553 YqbF, hypothetical protein domain 7 48 2.6E-21 T 29-03-2018 IPR027926 Uncharacterised protein YqbF domain CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 Pfam PF00557 Metallopeptidase family M24 12 239 2.2E-49 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 Gene3D G3DSA:3.90.230.10 1 248 3.2E-74 T 29-03-2018 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 36.776 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.4E-17 T 29-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 2.2E-85 T 29-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CSW12_RS19760 a93d65df29635b8772c6621437604fbf 248 SUPERFAMILY SSF55920 1 247 1.44E-78 T 29-03-2018 IPR000994 Peptidase M24 CSW12_RS23260 1fc47569a349249130162a17766db6e9 78 Pfam PF10830 Protein of unknown function (DUF2553) 6 78 9.8E-16 T 29-03-2018 IPR020140 Uncharacterised protein family YusG CSW12_RS23260 1fc47569a349249130162a17766db6e9 78 ProDom PD058325 YUSG BH3483 1 78 2.0E-39 T 29-03-2018 IPR020140 Uncharacterised protein family YusG CSW12_RS16595 bf2380e7559dda7710624e7e558ed911 384 Gene3D G3DSA:3.40.50.2000 205 371 6.1E-4 T 29-03-2018 CSW12_RS01720 dad87d1972bcbdd56e2049f5b8bc8693 182 Pfam PF09335 SNARE associated Golgi protein 33 150 1.8E-17 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS02515 cd2e7964331bfe926dd50b46c30a519b 610 Gene3D G3DSA:1.20.58.60 168 600 6.9E-8 T 29-03-2018 CSW12_RS30875 28d3d2c30fa367c471274a1d7cb8266a 167 SUPERFAMILY SSF48163 29 150 7.06E-6 T 29-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CSW12_RS30875 28d3d2c30fa367c471274a1d7cb8266a 167 SMART SM00530 7 68 1.8E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30875 28d3d2c30fa367c471274a1d7cb8266a 167 Pfam PF01381 Helix-turn-helix 9 68 1.6E-8 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS30875 28d3d2c30fa367c471274a1d7cb8266a 167 Gene3D G3DSA:1.10.3100.10 1 167 6.5E-21 T 29-03-2018 IPR027910 YdiL-like domain CSW12_RS30875 28d3d2c30fa367c471274a1d7cb8266a 167 SUPERFAMILY SSF47413 2 75 1.82E-12 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS04710 0c770c2f4d344a90bb96166793b1c7f2 649 Gene3D G3DSA:1.10.3950.10 384 522 3.2E-36 T 29-03-2018 CSW12_RS04710 0c770c2f4d344a90bb96166793b1c7f2 649 Pfam PF05569 BlaR1 peptidase M56 17 327 2.8E-60 T 29-03-2018 IPR008756 Peptidase M56 CSW12_RS04710 0c770c2f4d344a90bb96166793b1c7f2 649 Gene3D G3DSA:3.30.2010.10 160 250 2.3E-6 T 29-03-2018 CSW12_RS09965 a6c4681009422004cb25ea3327ec5ae5 313 SUPERFAMILY SSF103481 214 291 7.85E-7 T 29-03-2018 CSW12_RS09965 a6c4681009422004cb25ea3327ec5ae5 313 Pfam PF00892 EamA-like transporter family 10 150 2.9E-15 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS09965 a6c4681009422004cb25ea3327ec5ae5 313 TIGRFAM TIGR00688 rarD: protein RarD 9 266 2.7E-80 T 29-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CSW12_RS09965 a6c4681009422004cb25ea3327ec5ae5 313 SUPERFAMILY SSF103481 46 151 9.81E-11 T 29-03-2018 CSW12_RS23570 85eea10da394c8d837bd0dfc23e7dafa 338 Gene3D G3DSA:1.20.5.100 308 334 2.0E-5 T 29-03-2018 CSW12_RS23570 85eea10da394c8d837bd0dfc23e7dafa 338 Pfam PF11797 Protein of unknown function C-terminal (DUF3324) 159 294 1.9E-53 T 29-03-2018 IPR021759 Domain of unknown function DUF3324, C-terminal CSW12_RS23570 85eea10da394c8d837bd0dfc23e7dafa 338 Gene3D G3DSA:2.60.40.1710 37 158 3.4E-8 T 29-03-2018 CSW12_RS23570 85eea10da394c8d837bd0dfc23e7dafa 338 Pfam PF06030 Bacterial protein of unknown function (DUF916) 29 148 1.2E-42 T 29-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CSW12_RS23905 7449dcd1766a93aaa65a01541726ab60 182 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 74 114 8.5E-8 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CSW12_RS11800 bd88857d9b0e4e6dcd88982561e35788 325 Pfam PF02574 Homocysteine S-methyltransferase 19 310 6.6E-80 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS11800 bd88857d9b0e4e6dcd88982561e35788 325 PIRSF PIRSF037505 264 324 8.1E-4 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CSW12_RS11800 bd88857d9b0e4e6dcd88982561e35788 325 PIRSF PIRSF037505 7 105 3.9E-4 T 29-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CSW12_RS11800 bd88857d9b0e4e6dcd88982561e35788 325 SUPERFAMILY SSF82282 14 315 1.12E-84 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS11800 bd88857d9b0e4e6dcd88982561e35788 325 Gene3D G3DSA:3.20.20.330 1 324 4.9E-102 T 29-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CSW12_RS10315 f6818de279906e6d776a9f6b27bb49ac 466 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 62 199 1.9E-9 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain CSW12_RS10315 f6818de279906e6d776a9f6b27bb49ac 466 Gene3D G3DSA:3.20.20.190 36 354 8.8E-44 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS10315 f6818de279906e6d776a9f6b27bb49ac 466 SMART SM00148 55 201 3.7E-8 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain CSW12_RS10315 f6818de279906e6d776a9f6b27bb49ac 466 SUPERFAMILY SSF51695 41 277 1.26E-53 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS10315 f6818de279906e6d776a9f6b27bb49ac 466 SUPERFAMILY SSF51695 314 353 1.26E-53 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS14770 bd5ee5a3fb90a1161d7aa5f9ba263516 56 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 8 48 1.9E-5 T 29-03-2018 IPR019241 Protein of unknown function DUF2197 CSW12_RS18790 e0c68f0d019d8c1463068ee9df61ff4f 44 Pfam PF13070 Protein of unknown function (DUF3934) 1 42 2.6E-21 T 29-03-2018 IPR025175 Protein of unknown function DUF3934 CSW12_RS05620 dd8fa99d759378cc9a42585af91bb782 323 Gene3D G3DSA:3.40.50.720 1 189 4.8E-33 T 29-03-2018 CSW12_RS05620 dd8fa99d759378cc9a42585af91bb782 323 Gene3D G3DSA:3.90.25.10 190 323 1.4E-48 T 29-03-2018 CSW12_RS05620 dd8fa99d759378cc9a42585af91bb782 323 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 306 5.5E-95 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS05620 dd8fa99d759378cc9a42585af91bb782 323 SUPERFAMILY SSF51735 1 317 2.48E-93 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS05620 dd8fa99d759378cc9a42585af91bb782 323 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 320 2.6E-152 T 29-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CSW12_RS17525 fa95b3f478a54bd9b4a71b6e2e0f0f0a 384 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 176 376 1.4E-64 T 29-03-2018 IPR010897 Sporulation stage II, protein P CSW12_RS17525 fa95b3f478a54bd9b4a71b6e2e0f0f0a 384 SUPERFAMILY SSF53187 209 376 1.38E-6 T 29-03-2018 CSW12_RS17525 fa95b3f478a54bd9b4a71b6e2e0f0f0a 384 Gene3D G3DSA:3.40.630.40 175 377 2.0E-13 T 29-03-2018 CSW12_RS17525 fa95b3f478a54bd9b4a71b6e2e0f0f0a 384 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 101 371 4.9E-69 T 29-03-2018 IPR010897 Sporulation stage II, protein P CSW12_RS19010 17b02b719c9ae7a430d16c379444ea7b 103 Pfam PF12650 Domain of unknown function (DUF3784) 10 95 1.1E-7 T 29-03-2018 IPR017259 Uncharacterised conserved protein UCP037672 CSW12_RS17130 5c4f013b29af3e4d37d63e18bde36005 84 Pfam PF14201 Domain of unknown function (DUF4318) 14 84 6.2E-24 T 29-03-2018 IPR025467 Protein of unknown function DUF4318 CSW12_RS01210 aa2ac81b981838f1c31d1bf2c092d912 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 180 3.2E-29 T 29-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CSW12_RS30790 23879d6fcb092a5d1039ca3131b537e4 393 Pfam PF01580 FtsK/SpoIIIE family 127 234 7.6E-20 T 29-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CSW12_RS30790 23879d6fcb092a5d1039ca3131b537e4 393 SUPERFAMILY SSF52540 133 339 3.1E-18 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30790 23879d6fcb092a5d1039ca3131b537e4 393 Gene3D G3DSA:3.40.50.300 15 372 4.6E-16 T 29-03-2018 CSW12_RS04095 433e32450037a4c5d7c97cbed29dc722 197 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 65 87 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS04095 433e32450037a4c5d7c97cbed29dc722 197 Pfam PF01066 CDP-alcohol phosphatidyltransferase 24 87 7.9E-16 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS04095 433e32450037a4c5d7c97cbed29dc722 197 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 29 181 1.1E-54 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CSW12_RS19895 7775ee716505df849375f890a7b75a4a 278 PIRSF PIRSF000388 1 266 2.7E-110 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CSW12_RS19895 7775ee716505df849375f890a7b75a4a 278 Gene3D G3DSA:3.20.20.60 2 263 3.8E-84 T 29-03-2018 CSW12_RS19895 7775ee716505df849375f890a7b75a4a 278 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 263 2.1E-119 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CSW12_RS19895 7775ee716505df849375f890a7b75a4a 278 SUPERFAMILY SSF51621 3 263 5.1E-109 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS19895 7775ee716505df849375f890a7b75a4a 278 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 259 8.6E-114 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CSW12_RS19895 7775ee716505df849375f890a7b75a4a 278 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 43.469 T 29-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CSW12_RS05995 eedbf9ccc9948ac7429d7dcd7f80cb48 730 SUPERFAMILY SSF82866 184 341 4.71E-31 T 29-03-2018 CSW12_RS05995 eedbf9ccc9948ac7429d7dcd7f80cb48 730 Pfam PF03176 MMPL family 396 727 1.1E-38 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CSW12_RS05995 eedbf9ccc9948ac7429d7dcd7f80cb48 730 Pfam PF03176 MMPL family 59 366 3.7E-47 T 29-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CSW12_RS05995 eedbf9ccc9948ac7429d7dcd7f80cb48 730 SUPERFAMILY SSF82866 499 719 1.83E-32 T 29-03-2018 CSW12_RS05995 eedbf9ccc9948ac7429d7dcd7f80cb48 730 Gene3D G3DSA:1.20.1640.10 481 716 1.6E-35 T 29-03-2018 CSW12_RS05995 eedbf9ccc9948ac7429d7dcd7f80cb48 730 Gene3D G3DSA:1.20.1640.10 117 339 5.7E-38 T 29-03-2018 CSW12_RS17880 8f6539c9932996dd8050dca76d19b31b 65 Pfam PF13314 Domain of unknown function (DUF4083) 7 63 4.1E-29 T 29-03-2018 IPR025143 Protein of unknown function DUF4083 CSW12_RS05505 5170f2b02328b069e99b9ff80d135815 414 PIRSF PIRSF007487 4 387 6.9E-105 T 29-03-2018 IPR021176 Competence-induced protein CoiA CSW12_RS05505 5170f2b02328b069e99b9ff80d135815 414 Pfam PF06054 Competence protein CoiA-like family 5 388 5.6E-65 T 29-03-2018 IPR010330 Competence-induced protein CoiA-like CSW12_RS29785 2194030e1ecd1ade5580188861b73583 236 Gene3D G3DSA:1.20.5.780 6 143 0.012 T 29-03-2018 CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 SUPERFAMILY SSF48371 329 659 1.97E-15 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 SUPERFAMILY SSF48371 267 300 1.97E-15 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 SUPERFAMILY SSF48371 713 730 1.97E-15 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 SUPERFAMILY SSF48371 765 864 1.97E-15 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 Gene3D G3DSA:1.25.10.10 343 442 1.9E-16 T 29-03-2018 IPR011989 Armadillo-like helical CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 Gene3D G3DSA:1.25.10.10 443 538 7.2E-15 T 29-03-2018 IPR011989 Armadillo-like helical CSW12_RS02520 32e758cf0c2a914a52700d238904857a 944 Gene3D G3DSA:1.25.10.10 539 741 4.7E-9 T 29-03-2018 IPR011989 Armadillo-like helical CSW12_RS31180 6b44b68c6585a06a3a254f60fbcb9b64 134 SUPERFAMILY SSF89447 18 68 3.84E-5 T 29-03-2018 CSW12_RS31180 6b44b68c6585a06a3a254f60fbcb9b64 134 Gene3D G3DSA:2.10.260.10 10 121 1.3E-6 T 29-03-2018 CSW12_RS17205 5b10b15640aa17cdafd57418fa00cf75 105 Pfam PF13806 Rieske-like [2Fe-2S] domain 9 103 2.0E-14 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CSW12_RS17205 5b10b15640aa17cdafd57418fa00cf75 105 Gene3D G3DSA:2.102.10.10 4 105 6.2E-25 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS17205 5b10b15640aa17cdafd57418fa00cf75 105 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 7 103 2.6E-25 T 29-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CSW12_RS17205 5b10b15640aa17cdafd57418fa00cf75 105 SUPERFAMILY SSF50022 7 105 5.5E-31 T 29-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CSW12_RS07550 9128b1cf6dab109f29635cc54bd69793 261 SUPERFAMILY SSF158560 2 83 3.01E-19 T 29-03-2018 CSW12_RS07550 9128b1cf6dab109f29635cc54bd69793 261 SUPERFAMILY SSF103473 83 238 5.49E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS07550 9128b1cf6dab109f29635cc54bd69793 261 Gene3D G3DSA:1.10.1900.10 1 68 4.5E-14 T 29-03-2018 CSW12_RS03035 66e048b3122824ece1ed3ab4a0013776 193 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 8 191 2.0E-59 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CSW12_RS03035 66e048b3122824ece1ed3ab4a0013776 193 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 191 33.071 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CSW12_RS03035 66e048b3122824ece1ed3ab4a0013776 193 Pfam PF02669 K+-transporting ATPase, c chain 10 189 2.9E-72 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CSW12_RS03035 66e048b3122824ece1ed3ab4a0013776 193 PIRSF PIRSF001296 4 193 2.7E-78 T 29-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 29-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 123 2.7E-46 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 SUPERFAMILY SSF81330 10 119 6.8E-35 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 126 28.672 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.3E-11 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.3E-11 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.3E-11 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS23020 e30c779558344bb338ebdfa9472a2e90 132 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 125 1.3E-49 T 29-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CSW12_RS06715 261ff2635d648ff22b603090f81ddc95 251 Gene3D G3DSA:3.40.50.1400 1 107 1.4E-18 T 29-03-2018 CSW12_RS06715 261ff2635d648ff22b603090f81ddc95 251 Pfam PF01903 CbiX 9 110 1.2E-25 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CSW12_RS06715 261ff2635d648ff22b603090f81ddc95 251 Pfam PF01903 CbiX 133 232 1.9E-20 T 29-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CSW12_RS06715 261ff2635d648ff22b603090f81ddc95 251 Gene3D G3DSA:3.40.50.1400 117 241 2.1E-19 T 29-03-2018 CSW12_RS06715 261ff2635d648ff22b603090f81ddc95 251 SUPERFAMILY SSF53800 1 239 6.76E-42 T 29-03-2018 CSW12_RS20540 61bf10ae63daf3cb1fff844fed65582f 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 1 53 1.2E-8 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CSW12_RS20540 61bf10ae63daf3cb1fff844fed65582f 127 Pfam PF06686 Stage III sporulation protein AC/AD protein family 68 121 8.0E-20 T 29-03-2018 IPR025664 Stage III sporulation protein AC/AD family CSW12_RS20540 61bf10ae63daf3cb1fff844fed65582f 127 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 27 124 2.8E-36 T 29-03-2018 IPR014211 Stage III sporulation protein AD CSW12_RS20160 223f2b799f8407ece6fdb2fb1fee94a5 457 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 7 448 5.4E-131 T 29-03-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 CSW12_RS20160 223f2b799f8407ece6fdb2fb1fee94a5 457 Pfam PF03553 Na+/H+ antiporter family 154 444 4.6E-57 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CSW12_RS22270 e93368fa75e6d4579e4caf68642223eb 289 Pfam PF13349 Putative adhesin 40 287 3.5E-34 T 29-03-2018 IPR025164 Putative adhesin CSW12_RS05530 32263c9ac3eab46f01fb2d4aa3c319fc 192 PIRSF PIRSF012526 1 191 4.7E-77 T 29-03-2018 IPR009195 Uncharacterised protein family YjbK CSW12_RS05530 32263c9ac3eab46f01fb2d4aa3c319fc 192 SUPERFAMILY SSF55154 5 186 1.8E-30 T 29-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CSW12_RS05530 32263c9ac3eab46f01fb2d4aa3c319fc 192 Pfam PF01928 CYTH domain 4 184 5.9E-31 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CSW12_RS05530 32263c9ac3eab46f01fb2d4aa3c319fc 192 SMART SM01118 4 190 1.4E-23 T 29-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CSW12_RS05530 32263c9ac3eab46f01fb2d4aa3c319fc 192 Gene3D G3DSA:2.40.320.10 1 176 9.0E-34 T 29-03-2018 CSW12_RS03340 ee0edb12a8e3e57fa954761a53e9d7e5 244 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 12 233 5.5E-83 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CSW12_RS03340 ee0edb12a8e3e57fa954761a53e9d7e5 244 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 226 8.7E-55 T 29-03-2018 IPR011737 Conserved hypothetical protein CHP02206, TP0381 CSW12_RS20715 6de3f63cc16dbf3adadba58deda3be02 74 Pfam PF13066 Protein of unknown function (DUF3929) 8 71 2.7E-46 T 29-03-2018 IPR025171 Protein of unknown function DUF3929 CSW12_RS04740 91a5716062a125cc13c3a290a501594b 169 SUPERFAMILY SSF55729 1 165 2.06E-28 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS04740 91a5716062a125cc13c3a290a501594b 169 Pfam PF00583 Acetyltransferase (GNAT) family 41 141 4.7E-16 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS04740 91a5716062a125cc13c3a290a501594b 169 Gene3D G3DSA:3.40.630.30 1 166 9.2E-27 T 29-03-2018 CSW12_RS00610 1652e8843d26bf5234482632a440fcae 79 Pfam PF12728 Helix-turn-helix domain 5 53 1.1E-9 T 29-03-2018 CSW12_RS00610 1652e8843d26bf5234482632a440fcae 79 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 53 1.6E-17 T 29-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CSW12_RS29830 6ea3d8fe791dfab0be352a528134e32f 184 SUPERFAMILY SSF46955 8 123 5.95E-11 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS29830 6ea3d8fe791dfab0be352a528134e32f 184 Pfam PF13411 MerR HTH family regulatory protein 8 72 3.7E-12 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS29830 6ea3d8fe791dfab0be352a528134e32f 184 Gene3D G3DSA:1.10.1660.10 7 178 4.2E-14 T 29-03-2018 CSW12_RS07205 279d9ff9b555cbb6e027d399d14e78ba 183 Gene3D G3DSA:3.40.630.30 6 183 1.2E-24 T 29-03-2018 CSW12_RS07205 279d9ff9b555cbb6e027d399d14e78ba 183 Pfam PF13302 Acetyltransferase (GNAT) domain 16 156 9.2E-17 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS07205 279d9ff9b555cbb6e027d399d14e78ba 183 SUPERFAMILY SSF55729 9 182 2.61E-36 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17375 8cec99d4569cd8ff8d07dc5b54ac1162 226 Gene3D G3DSA:3.40.50.150 26 219 3.1E-37 T 29-03-2018 CSW12_RS17375 8cec99d4569cd8ff8d07dc5b54ac1162 226 Pfam PF08241 Methyltransferase domain 52 144 2.1E-23 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS17375 8cec99d4569cd8ff8d07dc5b54ac1162 226 SUPERFAMILY SSF53335 10 195 1.37E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS18975 5c68e4eaca83349acecf9644f6e21a28 126 Pfam PF13411 MerR HTH family regulatory protein 3 69 4.6E-16 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS18975 5c68e4eaca83349acecf9644f6e21a28 126 SMART SM00422 3 72 2.4E-17 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS18975 5c68e4eaca83349acecf9644f6e21a28 126 Gene3D G3DSA:1.10.1660.10 1 59 1.7E-19 T 29-03-2018 CSW12_RS18975 5c68e4eaca83349acecf9644f6e21a28 126 Gene3D G3DSA:1.10.1660.10 60 125 5.5E-12 T 29-03-2018 CSW12_RS18975 5c68e4eaca83349acecf9644f6e21a28 126 SUPERFAMILY SSF46955 3 120 1.61E-29 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS26920 050deed8d7316a9cfad65ff037836086 326 Gene3D G3DSA:3.90.550.10 2 316 5.2E-54 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS26920 050deed8d7316a9cfad65ff037836086 326 Pfam PF00535 Glycosyl transferase family 2 9 140 2.0E-38 T 29-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CSW12_RS26920 050deed8d7316a9cfad65ff037836086 326 SUPERFAMILY SSF53448 7 226 6.57E-65 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS18450 d6b5b7396f80cf45c47a12cbb485cf74 608 Pfam PF13520 Amino acid permease 29 444 9.3E-33 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS28440 dfbce0261d0ee0c17f4ea42b1faf8095 216 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 24 207 3.6E-46 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CSW12_RS28440 dfbce0261d0ee0c17f4ea42b1faf8095 216 Pfam PF04973 Nicotinamide mononucleotide transporter 25 203 3.9E-42 T 29-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CSW12_RS21460 b35f57c8a3e3acace36225a144368264 131 Gene3D G3DSA:1.25.40.20 75 121 0.01 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS21460 b35f57c8a3e3acace36225a144368264 131 Gene3D G3DSA:1.25.40.20 10 74 1.5E-5 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS21460 b35f57c8a3e3acace36225a144368264 131 SUPERFAMILY SSF48403 17 113 2.33E-8 T 29-03-2018 IPR020683 Ankyrin repeat-containing domain CSW12_RS26710 f8fef9944068ba690ce1d25e80975e9d 281 Gene3D G3DSA:3.30.930.10 2 270 6.3E-41 T 29-03-2018 CSW12_RS26710 f8fef9944068ba690ce1d25e80975e9d 281 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 278 51.459 T 29-03-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987 CSW12_RS26710 f8fef9944068ba690ce1d25e80975e9d 281 Pfam PF03099 Biotin/lipoate A/B protein ligase family 75 182 5.9E-13 T 29-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CSW12_RS26710 f8fef9944068ba690ce1d25e80975e9d 281 SUPERFAMILY SSF55681 7 266 1.82E-69 T 29-03-2018 CSW12_RS29365 e470cf66a2a6c47dc8377eef15b43df1 118 Gene3D G3DSA:1.10.1220.10 13 66 0.018 T 29-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CSW12_RS30465 8ac42bd26ee37940b1bbe543c66e7b5b 133 Pfam PF12666 PrgI family protein 9 97 8.1E-22 T 29-03-2018 IPR024414 Uncharacterised protein family PrgI CSW12_RS29700 8ac42bd26ee37940b1bbe543c66e7b5b 133 Pfam PF12666 PrgI family protein 9 97 8.1E-22 T 29-03-2018 IPR024414 Uncharacterised protein family PrgI CSW12_RS06530 1d58820db18e3ff6f5611483022257d8 155 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 50 147 6.7E-25 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS06530 1d58820db18e3ff6f5611483022257d8 155 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 22 151 6.0E-46 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS06530 1d58820db18e3ff6f5611483022257d8 155 PIRSF PIRSF021377 20 154 2.5E-47 T 29-03-2018 IPR014229 Sporulation protein YtfJ CSW12_RS17905 20cd123ff79f78f6041257c5762336f4 55 Pfam PF13069 Protein of unknown function (DUF3933) 1 52 1.9E-35 T 29-03-2018 IPR025174 Protein of unknown function DUF3933 CSW12_RS20865 7ff2a9c1a9d5b2d6b749140957cceaf5 86 Pfam PF13110 Protein of unknown function (DUF3966) 35 84 2.3E-38 T 29-03-2018 IPR025084 Protein of unknown function DUF3966 CSW12_RS05955 90025efe95b5ff0da4798d35fabd33cd 44 Pfam PF08671 Anti-repressor SinI 9 36 4.2E-12 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CSW12_RS05955 90025efe95b5ff0da4798d35fabd33cd 44 SUPERFAMILY SSF47406 8 35 2.62E-7 T 29-03-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 CSW12_RS15385 b74c2c9ce9adb872df85a9c4733ed8e6 359 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 194 356 3.3E-31 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS15385 b74c2c9ce9adb872df85a9c4733ed8e6 359 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 3 358 3.4E-100 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS00100 6c2ed63385681d2844ce7b840ae1ec8e 125 Pfam PF11127 Protein of unknown function (DUF2892) 1 60 2.8E-11 T 29-03-2018 IPR021309 Protein of unknown function DUF2892 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 Pfam PF00375 Sodium:dicarboxylate symporter family 32 443 3.9E-99 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 SUPERFAMILY SSF118215 31 443 1.44E-93 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 PRINTS PR00173 Glutamate-aspartate symporter signature 106 131 3.1E-17 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 PRINTS PR00173 Glutamate-aspartate symporter signature 397 417 3.1E-17 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 PRINTS PR00173 Glutamate-aspartate symporter signature 370 389 3.1E-17 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 PRINTS PR00173 Glutamate-aspartate symporter signature 233 252 3.1E-17 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 PRINTS PR00173 Glutamate-aspartate symporter signature 76 96 3.1E-17 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS20835 d84ba3d77197a8ad04ee4ed28fbb753f 464 Gene3D G3DSA:1.10.3860.10 19 450 2.1E-90 T 29-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 Gene3D G3DSA:1.10.287.1060 229 321 0.001 T 29-03-2018 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 SMART SM00283 286 561 4.4E-81 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 514 4.2E-47 T 29-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 SUPERFAMILY SSF58104 292 561 1.27E-75 T 29-03-2018 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 SUPERFAMILY SSF58104 225 259 1.27E-75 T 29-03-2018 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 Gene3D G3DSA:1.10.287.950 322 563 8.9E-53 T 29-03-2018 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 Pfam PF00672 HAMP domain 205 254 7.4E-9 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS24995 c8059544ca3100ad032ac2ad245b0401 563 SMART SM00304 203 257 1.3E-12 T 29-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CSW12_RS16090 ddec4c785bcd9e175fba825b43391ce2 626 PIRSF PIRSF018968 1 375 1.1E-40 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS16090 ddec4c785bcd9e175fba825b43391ce2 626 PIRSF PIRSF018968 417 621 1.3E-22 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS16090 ddec4c785bcd9e175fba825b43391ce2 626 Pfam PF02687 FtsX-like permease family 84 179 3.7E-9 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS21385 0214df135451a6c800450dd519089f65 178 Gene3D G3DSA:3.40.50.1460 5 167 3.6E-6 T 29-03-2018 CSW12_RS12050 1fdeee750148e8f3f8507f21485f6871 405 Pfam PF01266 FAD dependent oxidoreductase 30 383 2.0E-44 T 29-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CSW12_RS12050 1fdeee750148e8f3f8507f21485f6871 405 SUPERFAMILY SSF51905 28 253 7.56E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS12050 1fdeee750148e8f3f8507f21485f6871 405 SUPERFAMILY SSF51905 345 392 7.56E-32 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS12050 1fdeee750148e8f3f8507f21485f6871 405 Gene3D G3DSA:3.50.50.60 17 401 3.1E-25 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS22120 4610dce66b1a6fcb26f49247b00907da 321 Pfam PF13536 Putative multidrug resistance efflux transporter 38 304 4.9E-90 T 29-03-2018 IPR032713 Putative multidrug resistance efflux transporter CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 411 3.5E-52 T 29-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 Pfam PF02056 Family 4 glycosyl hydrolase 5 186 7.8E-72 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 Gene3D G3DSA:3.90.110.10 159 435 5.8E-94 T 29-03-2018 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 SUPERFAMILY SSF51735 3 167 4.47E-58 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 140 171 - T 29-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 SUPERFAMILY SSF56327 172 438 6.48E-101 T 29-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 97 110 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 76 92 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 8.0E-50 T 29-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CSW12_RS25765 e2b02851318955e708e71dc95a57e914 441 Gene3D G3DSA:3.40.50.720 2 158 4.4E-30 T 29-03-2018 CSW12_RS07355 2e133c6278e3e33d2b49fb86c65d3aa7 490 PIRSF PIRSF005690 8 490 4.6E-137 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS07355 2e133c6278e3e33d2b49fb86c65d3aa7 490 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 22 479 1.3E-152 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS12040 d4b16b180a2844e6ee6bd34e7967f0d7 173 SUPERFAMILY SSF53056 3 158 4.71E-18 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS12040 d4b16b180a2844e6ee6bd34e7967f0d7 173 Gene3D G3DSA:3.40.1050.10 2 159 6.1E-15 T 29-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CSW12_RS04585 7badef769c8d92a7483f945ce23d3e89 217 Pfam PF06161 Protein of unknown function (DUF975) 119 207 3.8E-29 T 29-03-2018 IPR010380 Protein of unknown function DUF975 CSW12_RS04585 7badef769c8d92a7483f945ce23d3e89 217 Pfam PF06161 Protein of unknown function (DUF975) 3 126 2.0E-11 T 29-03-2018 IPR010380 Protein of unknown function DUF975 CSW12_RS02650 45fd890b754fd2f19396819742d2e8e8 433 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 414 1.4E-124 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS02650 45fd890b754fd2f19396819742d2e8e8 433 Pfam PF05525 Branched-chain amino acid transport protein 6 426 3.6E-141 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS08025 8f24cc77390aa8189a0807bc68122186 307 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 26 303 7.1E-91 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CSW12_RS08025 8f24cc77390aa8189a0807bc68122186 307 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 82 104 - T 29-03-2018 IPR030470 UbiA prenyltransferase conserved site CSW12_RS08025 8f24cc77390aa8189a0807bc68122186 307 Pfam PF01040 UbiA prenyltransferase family 41 290 6.5E-55 T 29-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CSW12_RS08025 8f24cc77390aa8189a0807bc68122186 307 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 22 306 17.971 T 29-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CSW12_RS11065 68f052f7d339522c2fb8180742b8f5b3 294 SUPERFAMILY SSF103481 40 145 2.55E-15 T 29-03-2018 CSW12_RS11065 68f052f7d339522c2fb8180742b8f5b3 294 Pfam PF00892 EamA-like transporter family 154 290 3.3E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS11065 68f052f7d339522c2fb8180742b8f5b3 294 Pfam PF00892 EamA-like transporter family 6 143 2.3E-26 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS11065 68f052f7d339522c2fb8180742b8f5b3 294 SUPERFAMILY SSF103481 190 291 1.57E-15 T 29-03-2018 CSW12_RS29320 e3816d2ad19210eb3fc13253e736be47 180 SUPERFAMILY SSF46955 13 133 2.11E-8 T 29-03-2018 IPR009061 Putative DNA-binding domain CSW12_RS29320 e3816d2ad19210eb3fc13253e736be47 180 Pfam PF13411 MerR HTH family regulatory protein 13 80 1.0E-6 T 29-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CSW12_RS29320 e3816d2ad19210eb3fc13253e736be47 180 Gene3D G3DSA:1.10.1660.10 3 176 6.6E-18 T 29-03-2018 CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 395 572 6.0E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 283 3.7E-11 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 SUPERFAMILY SSF161098 313 568 1.59E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 23 583 1.1E-250 T 29-03-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 SUPERFAMILY SSF161098 21 287 2.8E-50 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 Gene3D G3DSA:1.10.3720.10 308 579 5.5E-27 T 29-03-2018 CSW12_RS06165 b97fbeb7148b87294bd438b1bf91d7cc 583 Gene3D G3DSA:1.10.3720.10 25 290 6.9E-39 T 29-03-2018 CSW12_RS24350 a8e8a2bf635935079566d5c8d26fcd30 237 Pfam PF08713 DNA alkylation repair enzyme 8 221 6.9E-72 T 29-03-2018 IPR014825 DNA alkylation repair enzyme CSW12_RS24350 a8e8a2bf635935079566d5c8d26fcd30 237 Gene3D G3DSA:1.25.40.290 128 226 1.4E-23 T 29-03-2018 CSW12_RS24350 a8e8a2bf635935079566d5c8d26fcd30 237 SUPERFAMILY SSF48371 12 223 2.26E-59 T 29-03-2018 IPR016024 Armadillo-type fold GO:0005488 CSW12_RS24350 a8e8a2bf635935079566d5c8d26fcd30 237 Gene3D G3DSA:1.20.1660.10 6 127 1.5E-32 T 29-03-2018 CSW12_RS02350 7939b6d8d2abf8f78cab0bb618cac584 348 SUPERFAMILY SSF56219 34 324 5.04E-76 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS02350 7939b6d8d2abf8f78cab0bb618cac584 348 Gene3D G3DSA:3.60.10.10 22 324 4.5E-33 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS02350 7939b6d8d2abf8f78cab0bb618cac584 348 TIGRFAM TIGR03395 sphingomy: sphingomyelin phosphodiesterase 37 325 1.7E-141 T 29-03-2018 IPR017766 Sphingomyelinase C/phospholipase C GO:0005576|GO:0008081 CSW12_RS02350 7939b6d8d2abf8f78cab0bb618cac584 348 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 40 289 1.7E-15 T 29-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CSW12_RS18385 a55c1b659d518231334b7c04d1c9bb96 217 Pfam PF02517 CAAX protease self-immunity 124 212 9.8E-13 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS10290 74902c7f1a42638cbb4211aec6398157 497 PIRSF PIRSF005690 11 496 1.7E-167 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS10290 74902c7f1a42638cbb4211aec6398157 497 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 30 484 3.2E-166 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS14510 20981beaf558c14b306142a73664d809 64 Pfam PF00589 Phage integrase family 3 47 1.5E-12 T 29-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS14510 20981beaf558c14b306142a73664d809 64 SUPERFAMILY SSF56349 2 55 5.3E-17 T 29-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CSW12_RS14510 20981beaf558c14b306142a73664d809 64 Gene3D G3DSA:1.10.443.10 1 62 9.2E-15 T 29-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CSW12_RS20550 dc5db200f430c62462556a688e881497 171 PIRSF PIRSF021435 1 171 4.5E-74 T 29-03-2018 IPR014198 Stage III sporulation protein AB CSW12_RS20550 dc5db200f430c62462556a688e881497 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 4.2E-71 T 29-03-2018 IPR014198 Stage III sporulation protein AB CSW12_RS20550 dc5db200f430c62462556a688e881497 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 5.3E-56 T 29-03-2018 IPR014198 Stage III sporulation protein AB CSW12_RS26570 35ea302ee238644b8654a41ace4cf801 300 SMART SM00382 29 205 2.0E-14 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS26570 35ea302ee238644b8654a41ace4cf801 300 Gene3D G3DSA:3.40.50.300 1 269 1.2E-65 T 29-03-2018 CSW12_RS26570 35ea302ee238644b8654a41ace4cf801 300 Pfam PF00005 ABC transporter 20 156 2.3E-29 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS26570 35ea302ee238644b8654a41ace4cf801 300 SUPERFAMILY SSF52540 3 220 1.47E-61 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS26570 35ea302ee238644b8654a41ace4cf801 300 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS08710 ac6addde6dd7b8c10f658c0e1465e312 103 Gene3D G3DSA:3.30.1330.30 1 99 4.3E-19 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS08710 ac6addde6dd7b8c10f658c0e1465e312 103 SUPERFAMILY SSF55315 3 98 2.17E-26 T 29-03-2018 IPR029064 50S ribosomal protein L30e-like CSW12_RS08710 ac6addde6dd7b8c10f658c0e1465e312 103 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4 93 1.4E-17 T 29-03-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CSW12_RS08075 6736bd4bef2749ebd1b11f655525e532 81 Pfam PF14003 YlbE-like protein 14 73 4.4E-27 T 29-03-2018 IPR025613 YlbE-like protein CSW12_RS03905 77ceebb81befbcf0e1f9f048730efa32 345 Gene3D G3DSA:3.40.190.10 153 323 4.2E-11 T 29-03-2018 CSW12_RS03905 77ceebb81befbcf0e1f9f048730efa32 345 PIRSF PIRSF017082 19 345 8.2E-86 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CSW12_RS03905 77ceebb81befbcf0e1f9f048730efa32 345 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 73 332 2.1E-22 T 29-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CSW12_RS03905 77ceebb81befbcf0e1f9f048730efa32 345 SUPERFAMILY SSF53850 136 312 2.39E-8 T 29-03-2018 CSW12_RS24530 9949936be2fb1cc475eb9213511869e7 264 Pfam PF10947 Protein of unknown function (DUF2628) 25 118 3.6E-22 T 29-03-2018 IPR024399 Protein of unknown function DUF2628 CSW12_RS24405 dfc7e8fc6625fa54ff99669836756e8d 105 Pfam PF14068 Putative membrane protein 6 105 8.3E-42 T 29-03-2018 IPR025917 Putative membrane protein YuiB CSW12_RS22150 4cb4d08b16eaadea217dd144d01b99ad 262 SUPERFAMILY SSF103088 135 257 6.8E-29 T 29-03-2018 IPR006665 OmpA-like domain CSW12_RS22150 4cb4d08b16eaadea217dd144d01b99ad 262 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 8 61 2.5E-21 T 29-03-2018 IPR025713 Motility protein B, N-terminal domain CSW12_RS22150 4cb4d08b16eaadea217dd144d01b99ad 262 Pfam PF00691 OmpA family 148 248 3.4E-16 T 29-03-2018 IPR006665 OmpA-like domain CSW12_RS22150 4cb4d08b16eaadea217dd144d01b99ad 262 Gene3D G3DSA:3.30.1330.60 75 262 8.1E-38 T 29-03-2018 IPR006665 OmpA-like domain CSW12_RS07995 45ab32e23538b2005b09c3699d06bc2a 165 Gene3D G3DSA:3.90.420.10 81 161 1.1E-4 T 29-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CSW12_RS07995 45ab32e23538b2005b09c3699d06bc2a 165 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 164 9.0E-91 T 29-03-2018 IPR020229 Uncharacterised protein YlaL CSW12_RS19800 715b365f36cd1c94dd456f7490ff35b9 184 Pfam PF06908 Protein of unknown function (DUF1273) 4 171 1.7E-70 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 CSW12_RS19800 715b365f36cd1c94dd456f7490ff35b9 184 SUPERFAMILY SSF102405 1 177 1.74E-63 T 29-03-2018 CSW12_RS19800 715b365f36cd1c94dd456f7490ff35b9 184 Hamap MF_01575 UPF0398 protein . 1 177 36.207 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 CSW12_RS19800 715b365f36cd1c94dd456f7490ff35b9 184 Gene3D G3DSA:3.40.50.450 1 180 1.6E-41 T 29-03-2018 CSW12_RS19800 715b365f36cd1c94dd456f7490ff35b9 184 PIRSF PIRSF021290 1 179 4.6E-75 T 29-03-2018 IPR010697 Protein of unknown function DUF1273 CSW12_RS19575 bb9897e95430af562a425cd23d81b20c 58 Pfam PF10782 Zinc-finger 2 58 2.6E-28 T 29-03-2018 IPR019718 Protein of unknown function DUF2602 CSW12_RS13150 503a86a50ed03b6f18b5a19de406e4ad 126 SUPERFAMILY SSF46785 8 81 2.61E-14 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13150 503a86a50ed03b6f18b5a19de406e4ad 126 Gene3D G3DSA:1.10.287.100 83 118 1.4E-15 T 29-03-2018 CSW12_RS13150 503a86a50ed03b6f18b5a19de406e4ad 126 SMART SM00345 15 74 0.0046 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS13150 503a86a50ed03b6f18b5a19de406e4ad 126 Gene3D G3DSA:1.10.10.10 11 82 1.6E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13150 503a86a50ed03b6f18b5a19de406e4ad 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-6 T 29-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CSW12_RS20860 4591bfd48be3f878223d439074684b31 124 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 6 90 9.6E-8 T 29-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 CSW12_RS20860 4591bfd48be3f878223d439074684b31 124 Gene3D G3DSA:3.40.50.450 1 116 1.4E-12 T 29-03-2018 CSW12_RS20860 4591bfd48be3f878223d439074684b31 124 SUPERFAMILY SSF52309 1 92 7.63E-8 T 29-03-2018 CSW12_RS09130 5b790d8c3dec859373acaeb9b3904e9d 100 Pfam PF02583 Metal-sensitive transcriptional repressor 16 95 2.3E-32 T 29-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CSW12_RS14535 762776f806e7ab0747b749438725bf88 182 Pfam PF07155 ECF-type riboflavin transporter, S component 3 170 4.5E-36 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CSW12_RS14535 762776f806e7ab0747b749438725bf88 182 Hamap MF_01572 UPF0397 protein . 2 181 21.225 T 29-03-2018 IPR022914 Protein of unknown function UPF0397 CSW12_RS20940 913a3a66222b921a0141cea94d9abfd9 49 Pfam PF00471 Ribosomal protein L33 3 49 1.9E-20 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS20940 913a3a66222b921a0141cea94d9abfd9 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 29-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CSW12_RS20940 913a3a66222b921a0141cea94d9abfd9 49 SUPERFAMILY SSF57829 1 49 9.16E-18 T 29-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CSW12_RS20940 913a3a66222b921a0141cea94d9abfd9 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.663 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS20940 913a3a66222b921a0141cea94d9abfd9 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.3E-18 T 29-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CSW12_RS03530 6012709ffe21ba9dcf3b4999aa7a74c1 112 Pfam PF01638 HxlR-like helix-turn-helix 26 109 3.1E-28 T 29-03-2018 IPR002577 Helix-turn-helix, HxlR type CSW12_RS03530 6012709ffe21ba9dcf3b4999aa7a74c1 112 SUPERFAMILY SSF46785 13 109 1.96E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS03530 6012709ffe21ba9dcf3b4999aa7a74c1 112 Gene3D G3DSA:1.10.10.10 24 107 2.7E-20 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.60.120.40 679 824 6.0E-23 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 579 652 3.7E-11 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 40 102 3.6E-10 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 103 171 3.5E-10 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 517 578 3.8E-13 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 172 247 1.4E-12 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 346 404 2.9E-13 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Gene3D G3DSA:2.160.20.50 405 483 6.4E-10 T 29-03-2018 CSW12_RS11150 8009d796d223401f50ff493687783f93 824 Pfam PF01391 Collagen triple helix repeat (20 copies) 625 682 1.7E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS30230 d9b3b3814b8bc0866ed8b607721e7004 228 Gene3D G3DSA:3.30.420.10 61 216 7.9E-16 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS30230 d9b3b3814b8bc0866ed8b607721e7004 228 Pfam PF13610 DDE domain 71 206 4.4E-44 T 29-03-2018 IPR032874 DDE domain CSW12_RS30230 d9b3b3814b8bc0866ed8b607721e7004 228 SUPERFAMILY SSF53098 70 191 4.55E-10 T 29-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CSW12_RS01270 49603620f962d08e3cda1aa39e8d7eef 261 Pfam PF06182 ABC-2 family transporter protein 34 260 6.7E-54 T 29-03-2018 IPR010390 Protein of unknown function DUF990 CSW12_RS04255 c485abc3072698724f6ca24e38f4de36 129 Pfam PF11181 Heat induced stress protein YflT 12 109 4.5E-31 T 29-03-2018 IPR025889 General stress protein 17M-like domain CSW12_RS07405 92bffebc60d83926fcb8727deebd1887 300 SMART SM00849 56 249 3.4E-5 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07405 92bffebc60d83926fcb8727deebd1887 300 Gene3D G3DSA:3.60.15.10 36 292 2.7E-27 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07405 92bffebc60d83926fcb8727deebd1887 300 Pfam PF00753 Metallo-beta-lactamase superfamily 54 247 1.2E-10 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS07405 92bffebc60d83926fcb8727deebd1887 300 SUPERFAMILY SSF56281 46 289 1.06E-47 T 29-03-2018 IPR001279 Metallo-beta-lactamase CSW12_RS03620 03628fd2b41e96bdda3418ce2dea8731 232 SUPERFAMILY SSF161098 25 227 7.19E-46 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03620 03628fd2b41e96bdda3418ce2dea8731 232 Gene3D G3DSA:1.10.3720.10 5 231 1.2E-38 T 29-03-2018 CSW12_RS03620 03628fd2b41e96bdda3418ce2dea8731 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 226 2.2E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03620 03628fd2b41e96bdda3418ce2dea8731 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 121 1.1E-32 T 29-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CSW12_RS26025 89a4969ca7fc294b79c509deaf9c780b 222 Pfam PF06930 Protein of unknown function (DUF1282) 20 210 4.2E-21 T 29-03-2018 IPR009698 Protein of unknown function DUF1282 CSW12_RS21860 12628c09f0c6e06278b17f3ba8c7be22 462 Gene3D G3DSA:2.40.50.140 31 108 2.5E-19 T 29-03-2018 CSW12_RS21860 12628c09f0c6e06278b17f3ba8c7be22 462 SUPERFAMILY SSF50249 38 106 9.14E-12 T 29-03-2018 IPR012340 Nucleic acid-binding, OB-fold CSW12_RS21860 12628c09f0c6e06278b17f3ba8c7be22 462 Pfam PF10150 Ribonuclease E/G family 106 364 4.6E-83 T 29-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CSW12_RS21860 12628c09f0c6e06278b17f3ba8c7be22 462 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 398 4.9E-106 T 29-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CSW12_RS15590 0bfb768f25639eeb8a2ec2b2687dc192 393 SUPERFAMILY SSF55909 48 389 8.39E-100 T 29-03-2018 CSW12_RS15590 0bfb768f25639eeb8a2ec2b2687dc192 393 Gene3D G3DSA:3.75.10.10 43 393 2.9E-105 T 29-03-2018 CSW12_RS15590 0bfb768f25639eeb8a2ec2b2687dc192 393 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 57 389 1.9E-91 T 29-03-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 CSW12_RS04285 0bea8455caf09795bbc89295b71aef74 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 8.1E-29 T 29-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CSW12_RS04285 0bea8455caf09795bbc89295b71aef74 111 Gene3D G3DSA:3.30.750.24 3 109 4.3E-18 T 29-03-2018 IPR002645 STAS domain CSW12_RS04285 0bea8455caf09795bbc89295b71aef74 111 SUPERFAMILY SSF52091 3 106 5.89E-25 T 29-03-2018 IPR002645 STAS domain CSW12_RS04285 0bea8455caf09795bbc89295b71aef74 111 Pfam PF01740 STAS domain 14 101 9.3E-17 T 29-03-2018 IPR002645 STAS domain CSW12_RS25910 afa3e532f55fe67cbb3985e11571145c 642 SUPERFAMILY SSF53649 246 619 1.23E-71 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS25910 afa3e532f55fe67cbb3985e11571145c 642 PIRSF PIRSF005091 1 623 3.5E-175 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CSW12_RS25910 afa3e532f55fe67cbb3985e11571145c 642 Gene3D G3DSA:3.40.720.10 240 548 5.4E-44 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS25910 afa3e532f55fe67cbb3985e11571145c 642 Pfam PF00884 Sulfatase 248 538 1.3E-37 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CSW12_RS20525 3b43d5a161adb70ba43147fc1bbb995f 220 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 33 220 3.2E-72 T 29-03-2018 IPR014195 Sporulation stage III, protein AG CSW12_RS28895 8035be011b738e14d63bf9ffabf40a10 319 Pfam PF12146 Serine aminopeptidase, S33 102 186 1.1E-14 T 29-03-2018 IPR022742 Serine aminopeptidase, S33 CSW12_RS28895 8035be011b738e14d63bf9ffabf40a10 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 140 2.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS28895 8035be011b738e14d63bf9ffabf40a10 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 172 185 2.7E-5 T 29-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CSW12_RS28895 8035be011b738e14d63bf9ffabf40a10 319 SUPERFAMILY SSF53474 69 316 6.49E-44 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS28895 8035be011b738e14d63bf9ffabf40a10 319 Gene3D G3DSA:3.40.50.1820 47 318 2.2E-40 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS12220 1a3a0ae48bf829606edf1aed9e2a92b6 393 Pfam PF12051 Protein of unknown function (DUF3533) 14 366 5.3E-25 T 29-03-2018 IPR022703 Domain of unknown function DUF3533 CSW12_RS12220 1a3a0ae48bf829606edf1aed9e2a92b6 393 Gene3D G3DSA:3.40.1710.10 27 211 6.1E-29 T 29-03-2018 CSW12_RS30310 4d0402d553ab2c25a848f7c008a81e4f 982 Pfam PF01526 Tn3 transposase DDE domain 578 965 4.6E-148 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 CSW12_RS30310 4d0402d553ab2c25a848f7c008a81e4f 982 Pfam PF13700 Domain of unknown function (DUF4158) 1 163 7.6E-32 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS09790 ea0d28e7bb37baf2317827df6d5e9ce4 297 SUPERFAMILY SSF52540 2 215 3.86E-52 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS09790 ea0d28e7bb37baf2317827df6d5e9ce4 297 Pfam PF00005 ABC transporter 19 156 3.7E-24 T 29-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CSW12_RS09790 ea0d28e7bb37baf2317827df6d5e9ce4 297 Gene3D G3DSA:3.40.50.300 1 275 6.7E-51 T 29-03-2018 CSW12_RS09790 ea0d28e7bb37baf2317827df6d5e9ce4 297 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 29-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CSW12_RS09790 ea0d28e7bb37baf2317827df6d5e9ce4 297 SMART SM00382 26 204 2.1E-10 T 29-03-2018 IPR003593 AAA+ ATPase domain CSW12_RS07345 11ad1072104a97955cf4fbb1aeaf7ebc 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 111 2.2E-41 T 29-03-2018 IPR005562 SpoVA CSW12_RS07345 11ad1072104a97955cf4fbb1aeaf7ebc 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 1.4E-54 T 29-03-2018 IPR014204 Sporulation stage V, protein AE CSW12_RS02720 82a0771d754a1ede70fad011784c74e5 471 ProSitePatterns PS00218 Amino acid permeases signature. 43 74 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS02720 82a0771d754a1ede70fad011784c74e5 471 Pfam PF00324 Amino acid permease 18 456 3.3E-128 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS02720 82a0771d754a1ede70fad011784c74e5 471 PIRSF PIRSF006060 1 471 1.1E-84 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS07325 eba8ba9efefcc50d41b056b0694652ac 206 Pfam PF12164 Stage V sporulation protein AA 2 88 1.9E-20 T 29-03-2018 IPR021997 Stage V sporulation protein AA CSW12_RS07325 eba8ba9efefcc50d41b056b0694652ac 206 Gene3D G3DSA:2.60.480.10 2 92 1.6E-24 T 29-03-2018 CSW12_RS19960 afa0449136f975de688f99dc0c51ea59 227 Pfam PF04298 Putative neutral zinc metallopeptidase 4 219 9.7E-94 T 29-03-2018 IPR007395 Putative neutral zinc metallopeptidase CSW12_RS28510 895e3525d4e5bed8f5fa3756c096ee5c 109 Pfam PF14470 Bacterial PH domain 13 104 6.7E-16 T 29-03-2018 CSW12_RS03020 9575c7e9dbc2f0d00d4f8cf4efdf88f1 26 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 3 26 7.0E-9 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CSW12_RS03020 9575c7e9dbc2f0d00d4f8cf4efdf88f1 26 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 26 4.8E-8 T 29-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CSW12_RS04380 eea89cac08eeb05b418c6589b7e9ad3d 61 Pfam PF14120 YhzD-like protein 1 61 6.9E-26 T 29-03-2018 IPR025544 YhzD-like protein CSW12_RS26800 dd901c90239ea3f45616b389ebb8e1ee 208 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 8 193 3.9E-9 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS30235 b0c6c6b08a62447aa393e2fb958753d2 316 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 27 316 2.9E-87 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS15100 6964021083695703e0f8041b8cd63f02 275 Gene3D G3DSA:2.40.50.110 165 251 2.7E-4 T 29-03-2018 CSW12_RS18850 58ad00f5d9105af9a38551d07b89711a 366 Pfam PF07730 Histidine kinase 177 243 2.6E-15 T 29-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CSW12_RS18850 58ad00f5d9105af9a38551d07b89711a 366 SUPERFAMILY SSF55874 262 366 1.78E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS18850 58ad00f5d9105af9a38551d07b89711a 366 Gene3D G3DSA:3.30.565.10 249 366 1.4E-11 T 29-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CSW12_RS06595 5559527e8134bb1fedbdc2e7beee64cc 194 Pfam PF00694 Aconitase C-terminal domain 2 123 7.7E-36 T 29-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CSW12_RS06595 5559527e8134bb1fedbdc2e7beee64cc 194 SUPERFAMILY SSF52016 2 189 3.53E-60 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CSW12_RS06595 5559527e8134bb1fedbdc2e7beee64cc 194 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 194 40.043 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CSW12_RS06595 5559527e8134bb1fedbdc2e7beee64cc 194 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 2 184 2.0E-73 T 29-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CSW12_RS06595 5559527e8134bb1fedbdc2e7beee64cc 194 Gene3D G3DSA:3.20.19.10 1 172 5.0E-48 T 29-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CSW12_RS03345 5dab450b5c7822602f93f8be76935e6e 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 275 6.1E-12 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03345 5dab450b5c7822602f93f8be76935e6e 279 SUPERFAMILY SSF161098 61 263 3.66E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03345 5dab450b5c7822602f93f8be76935e6e 279 Gene3D G3DSA:1.10.3720.10 3 268 3.7E-16 T 29-03-2018 CSW12_RS02745 f863572251b41d1996f61d4318690be2 492 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 17 477 6.8E-169 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS02745 f863572251b41d1996f61d4318690be2 492 PIRSF PIRSF005690 6 492 7.9E-165 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS09600 64f7b3e77f18faa3af5fe91272791a4c 262 Pfam PF01381 Helix-turn-helix 9 61 8.6E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS09600 64f7b3e77f18faa3af5fe91272791a4c 262 SMART SM00530 6 61 2.4E-15 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS09600 64f7b3e77f18faa3af5fe91272791a4c 262 Gene3D G3DSA:1.10.260.40 1 179 1.1E-22 T 29-03-2018 CSW12_RS09600 64f7b3e77f18faa3af5fe91272791a4c 262 SUPERFAMILY SSF47413 2 66 3.84E-18 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS20965 208b6b6f3997dd20449194a13529a2a7 316 SUPERFAMILY SSF161098 36 308 1.4E-33 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS20965 208b6b6f3997dd20449194a13529a2a7 316 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 33 312 4.1E-79 T 29-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CSW12_RS20965 208b6b6f3997dd20449194a13529a2a7 316 Gene3D G3DSA:1.10.3720.10 20 307 1.5E-37 T 29-03-2018 CSW12_RS20965 208b6b6f3997dd20449194a13529a2a7 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 1.6E-18 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS14015 cdbbcae9d3b7c7bf10c768c213b12745 162 SMART SM00871 1 156 4.6E-31 T 29-03-2018 IPR010499 Bacterial transcription activator, effector binding CSW12_RS14015 cdbbcae9d3b7c7bf10c768c213b12745 162 SUPERFAMILY SSF55136 1 156 1.71E-28 T 29-03-2018 CSW12_RS14015 cdbbcae9d3b7c7bf10c768c213b12745 162 Gene3D G3DSA:3.20.80.10 1 160 6.5E-26 T 29-03-2018 IPR011256 Regulatory factor, effector binding domain CSW12_RS14015 cdbbcae9d3b7c7bf10c768c213b12745 162 Pfam PF06445 GyrI-like small molecule binding domain 1 156 4.0E-32 T 29-03-2018 IPR029442 GyrI-like small molecule binding domain CSW12_RS25965 0ec4a0642673fe2d017e1f1cd341874c 100 Pfam PF13049 Protein of unknown function (DUF3910) 1 93 4.2E-66 T 29-03-2018 IPR025021 Protein of unknown function DUF3910 CSW12_RS05005 eb4b870ddb31d88a653ba935ac179235 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 8.3E-29 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CSW12_RS09960 1f2714805c7b6a0935d10b654d832435 82 Pfam PF06961 Protein of unknown function (DUF1294) 10 64 8.6E-27 T 29-03-2018 IPR010718 Protein of unknown function DUF1294 CSW12_RS09960 1f2714805c7b6a0935d10b654d832435 82 PIRSF PIRSF002599 2 82 2.2E-11 T 29-03-2018 IPR012156 Cold shock, CspA GO:0003676 CSW12_RS03365 5d9ade5b0e68644cce3f7f67e67ae5fd 189 SUPERFAMILY SSF47240 1 186 8.75E-69 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS03365 5d9ade5b0e68644cce3f7f67e67ae5fd 189 Pfam PF05067 Manganese containing catalase 1 185 2.9E-76 T 29-03-2018 IPR007760 Manganese catalase CSW12_RS03365 5d9ade5b0e68644cce3f7f67e67ae5fd 189 Gene3D G3DSA:1.20.1260.10 1 184 5.0E-54 T 29-03-2018 IPR012347 Ferritin-related CSW12_RS26050 ab33b5b8be10201fe8bcafb9991bdf14 170 Pfam PF11683 Protein of unknown function (DUF3278) 16 124 1.8E-10 T 29-03-2018 IPR021697 Protein of unknown function DUF3278 CSW12_RS16775 b9669e4bbfd19fb8930e4c7b12674c3d 328 SUPERFAMILY SSF53187 1 180 9.42E-49 T 29-03-2018 CSW12_RS16775 b9669e4bbfd19fb8930e4c7b12674c3d 328 SMART SM00646 62 175 4.7E-32 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS16775 b9669e4bbfd19fb8930e4c7b12674c3d 328 Gene3D G3DSA:2.30.30.410 182 262 6.6E-10 T 29-03-2018 CSW12_RS16775 b9669e4bbfd19fb8930e4c7b12674c3d 328 Gene3D G3DSA:2.30.30.410 263 327 2.3E-7 T 29-03-2018 CSW12_RS16775 b9669e4bbfd19fb8930e4c7b12674c3d 328 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 175 5.9E-44 T 29-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CSW12_RS16775 b9669e4bbfd19fb8930e4c7b12674c3d 328 Gene3D G3DSA:3.40.630.40 1 181 1.1E-52 T 29-03-2018 CSW12_RS01200 d86aec1ac7eedd8b6bd45289cb61032d 52 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 50 16.381 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 CSW12_RS01200 d86aec1ac7eedd8b6bd45289cb61032d 52 Pfam PF08176 Small acid-soluble spore protein K family 1 48 6.4E-25 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 CSW12_RS01200 d86aec1ac7eedd8b6bd45289cb61032d 52 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 17 48 1.9E-22 T 29-03-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 CSW12_RS16135 3d5091d179704f75ea96587c28c725a7 174 Gene3D G3DSA:1.20.120.450 7 168 2.0E-18 T 29-03-2018 CSW12_RS16135 3d5091d179704f75ea96587c28c725a7 174 Pfam PF05163 DinB family 4 170 9.2E-33 T 29-03-2018 IPR007837 DNA damage-inducible protein DinB CSW12_RS16135 3d5091d179704f75ea96587c28c725a7 174 SUPERFAMILY SSF109854 7 165 1.58E-29 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS28960 bcd5655f1d0cdef4a07e1f35251e997d 240 Pfam PF08241 Methyltransferase domain 98 149 2.4E-13 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS28960 bcd5655f1d0cdef4a07e1f35251e997d 240 Gene3D G3DSA:3.40.50.150 85 211 8.8E-12 T 29-03-2018 CSW12_RS28960 bcd5655f1d0cdef4a07e1f35251e997d 240 SUPERFAMILY SSF53335 100 176 2.05E-14 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS01180 7550e0ac5eb3d609d194c5e79c9f2cfd 301 Gene3D G3DSA:3.40.50.720 2 301 1.6E-33 T 29-03-2018 CSW12_RS01180 7550e0ac5eb3d609d194c5e79c9f2cfd 301 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 7.3E-18 T 29-03-2018 IPR013549 Domain of unknown function DUF1731 CSW12_RS01180 7550e0ac5eb3d609d194c5e79c9f2cfd 301 SUPERFAMILY SSF51735 2 288 5.79E-42 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS01180 7550e0ac5eb3d609d194c5e79c9f2cfd 301 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 8.1E-109 T 29-03-2018 IPR010099 Epimerase family protein SDR39U1 CSW12_RS01180 7550e0ac5eb3d609d194c5e79c9f2cfd 301 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 1.5E-18 T 29-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CSW12_RS17990 af2911aa7e19c296032c61a399a5f9bd 415 Gene3D G3DSA:2.130.10.130 57 289 7.4E-5 T 29-03-2018 CSW12_RS09650 3f8e3a1f313a92e86c4cf5375ccbc223 129 SUPERFAMILY SSF49764 32 123 1.07E-11 T 29-03-2018 IPR008978 HSP20-like chaperone CSW12_RS09650 3f8e3a1f313a92e86c4cf5375ccbc223 129 Gene3D G3DSA:2.60.40.790 30 126 7.0E-10 T 29-03-2018 IPR008978 HSP20-like chaperone CSW12_RS11410 52882d40fb18255fa621e5e2621fa243 240 Pfam PF14256 YwiC-like protein 5 130 2.5E-42 T 29-03-2018 IPR025576 YwiC-like protein CSW12_RS16580 630371f941636ff35e6b150316fa75cf 185 Gene3D G3DSA:3.40.50.620 27 164 1.4E-31 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS16580 630371f941636ff35e6b150316fa75cf 185 Pfam PF02698 DUF218 domain 38 175 9.3E-29 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CSW12_RS21500 0a28978d06f2a907c1f85b5eeeaf5c30 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 3.6E-63 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS21500 0a28978d06f2a907c1f85b5eeeaf5c30 307 Gene3D G3DSA:3.40.50.1100 139 306 1.1E-49 T 29-03-2018 CSW12_RS21500 0a28978d06f2a907c1f85b5eeeaf5c30 307 Gene3D G3DSA:3.40.50.1100 41 138 1.2E-32 T 29-03-2018 CSW12_RS21500 0a28978d06f2a907c1f85b5eeeaf5c30 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 29-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CSW12_RS21500 0a28978d06f2a907c1f85b5eeeaf5c30 307 SUPERFAMILY SSF53686 2 305 1.57E-90 T 29-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CSW12_RS19035 d915ea7e2e832bb73ff52192bc71f2d6 357 Gene3D G3DSA:2.130.10.10 3 351 4.9E-46 T 29-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CSW12_RS19035 d915ea7e2e832bb73ff52192bc71f2d6 357 SUPERFAMILY SSF110296 27 334 8.37E-45 T 29-03-2018 CSW12_RS27605 c10f557ebcfd7c6bce65f6b78162d51d 74 Pfam PF10955 Protein of unknown function (DUF2757) 1 74 1.0E-28 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CSW12_RS27605 c10f557ebcfd7c6bce65f6b78162d51d 74 ProDom PD057826 YABK 1 74 2.0E-37 T 29-03-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 CSW12_RS05160 514d18ed7724900311b69ef292299a05 394 Pfam PF04860 Phage portal protein 68 355 2.7E-31 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CSW12_RS27935 b4b3108cbd342744f8bc43bed3d7ae06 199 Gene3D G3DSA:3.40.50.150 19 199 5.1E-32 T 29-03-2018 CSW12_RS27935 b4b3108cbd342744f8bc43bed3d7ae06 199 Pfam PF05175 Methyltransferase small domain 28 195 7.9E-53 T 29-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CSW12_RS27935 b4b3108cbd342744f8bc43bed3d7ae06 199 SUPERFAMILY SSF53335 12 197 1.82E-40 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS30760 0aece7adbe6a173ab7b4c1725aa4683d 75 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 4 56 2.7E-7 T 29-03-2018 IPR018690 Protein of unknown function DUF2187 CSW12_RS12865 86ba65b020bcb2cb0972ab9ba2ce2294 174 Gene3D G3DSA:3.40.50.300 7 173 2.3E-14 T 29-03-2018 CSW12_RS12865 86ba65b020bcb2cb0972ab9ba2ce2294 174 SUPERFAMILY SSF52540 9 162 7.44E-19 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12865 86ba65b020bcb2cb0972ab9ba2ce2294 174 Pfam PF13671 AAA domain 10 124 1.7E-6 T 29-03-2018 CSW12_RS05015 86a5cdd8c666fc87bdc4e0387f1c8e2d 302 Gene3D G3DSA:3.90.850.10 54 302 1.1E-80 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CSW12_RS05015 86a5cdd8c666fc87bdc4e0387f1c8e2d 302 SUPERFAMILY SSF56529 82 301 5.63E-75 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CSW12_RS05015 86a5cdd8c666fc87bdc4e0387f1c8e2d 302 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 94 301 1.9E-70 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CSW12_RS05150 f25ef7da377a82f9ce46fdd8a099b775 574 Pfam PF03354 Phage Terminase 78 547 3.5E-64 T 29-03-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type CSW12_RS13660 653138e52b1af00ccc8c251f245e4d0d 138 Pfam PF00583 Acetyltransferase (GNAT) family 36 116 1.3E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS13660 653138e52b1af00ccc8c251f245e4d0d 138 SUPERFAMILY SSF55729 13 138 1.61E-29 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS13660 653138e52b1af00ccc8c251f245e4d0d 138 Gene3D G3DSA:3.40.630.30 35 138 7.0E-19 T 29-03-2018 CSW12_RS04985 d826a9518ce577e8b5b03dccc0b9bad6 128 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 128 4.0E-66 T 29-03-2018 IPR024496 Spore germination protein GerPE CSW12_RS04985 d826a9518ce577e8b5b03dccc0b9bad6 128 Pfam PF10970 Spore germination protein GerPE 5 128 4.1E-49 T 29-03-2018 IPR024496 Spore germination protein GerPE CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 Gene3D G3DSA:3.40.50.720 12 278 1.5E-59 T 29-03-2018 CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 6.2E-24 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 3.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 3.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.1E-10 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 29-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 SUPERFAMILY SSF51735 13 283 3.82E-62 T 29-03-2018 IPR016040 NAD(P)-binding domain CSW12_RS13785 985b287928e70dcd3bacb16ba8732b2e 291 Pfam PF00106 short chain dehydrogenase 14 201 1.3E-48 T 29-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CSW12_RS28630 0a6c81f6ef08b452c968d91266d5501f 39 Pfam PF13134 Protein of unknown function (DUF3948) 4 38 7.5E-22 T 29-03-2018 IPR025034 Protein of unknown function DUF3948 CSW12_RS26005 5512524bb9d31347c9e4a6a0ce675854 71 Pfam PF11148 Protein of unknown function (DUF2922) 3 66 1.5E-16 T 29-03-2018 IPR021321 Protein of unknown function DUF2922 CSW12_RS30460 8971b44454eb4fdc42b27c8d9046c0f7 804 SUPERFAMILY SSF52540 425 779 1.03E-24 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS30460 8971b44454eb4fdc42b27c8d9046c0f7 804 Gene3D G3DSA:3.40.50.300 132 802 7.4E-16 T 29-03-2018 CSW12_RS11405 85a2ababfcd0d7dbe0def81b37a21c62 233 Pfam PF07155 ECF-type riboflavin transporter, S component 58 204 1.0E-10 T 29-03-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CSW12_RS11405 85a2ababfcd0d7dbe0def81b37a21c62 233 PIRSF PIRSF037395 1 233 2.4E-81 T 29-03-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 CSW12_RS04425 a80aa1f4ad6cb01f1c4ac2e9d405379a 96 TIGRFAM TIGR04429 Phr_nterm: Phr family secreted Rap phosphatase inhibitor 1 28 1.9E-9 T 29-03-2018 IPR030968 Phr family, secreted RapG/RapK phosphatase inhibitor CSW12_RS28900 4c2f6f1c278b6935c70e46be45ed1733 369 Pfam PF02371 Transposase IS116/IS110/IS902 family 226 299 8.1E-21 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS28900 4c2f6f1c278b6935c70e46be45ed1733 369 Pfam PF01548 Transposase 7 157 4.5E-13 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS00285 d70e5c8c0ec2c7dbdca14f224258a1dd 392 Pfam PF04860 Phage portal protein 51 355 2.0E-30 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 Gene3D G3DSA:3.30.230.10 1 115 4.3E-35 T 29-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 SUPERFAMILY SSF54211 1 109 1.67E-34 T 29-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 20.589 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 108 1.9E-33 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 Pfam PF00825 Ribonuclease P 1 107 2.4E-36 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 29-03-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 CSW12_RS27300 4c309b374e98980b0a309ddddf39478e 115 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 114 3.0E-57 T 29-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CSW12_RS09290 23d328cb405cb036e1bc571c44553761 267 Pfam PF13349 Putative adhesin 46 265 9.9E-28 T 29-03-2018 IPR025164 Putative adhesin CSW12_RS28490 9ee7fdfce2016b3eb129a7e4598bc36f 201 Gene3D G3DSA:3.40.1130.10 2 201 3.0E-39 T 29-03-2018 CSW12_RS28490 9ee7fdfce2016b3eb129a7e4598bc36f 201 SUPERFAMILY SSF69593 16 196 2.75E-39 T 29-03-2018 CSW12_RS28490 9ee7fdfce2016b3eb129a7e4598bc36f 201 SMART SM00563 33 144 1.1E-27 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CSW12_RS28490 9ee7fdfce2016b3eb129a7e4598bc36f 201 Pfam PF01553 Acyltransferase 18 141 3.8E-26 T 29-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CSW12_RS02290 53ac1a061ffeed345e26e4fd1452bd86 276 Gene3D G3DSA:1.10.10.10 15 103 1.4E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS25260 14a5f2fe1004f93b3e5ad1e3f100128b 426 Pfam PF00860 Permease family 13 392 3.3E-65 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS08855 d6b5271170a540820bd843027197a0fd 82 PIRSF PIRSF004764 1 82 1.3E-24 T 29-03-2018 IPR024702 Uncharacterised conserved protein YmfJ CSW12_RS08855 d6b5271170a540820bd843027197a0fd 82 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 8.9E-33 T 29-03-2018 IPR021637 Protein of unknown function DUF3243 CSW12_RS11575 6a2b1601c29c925bbb3e5ead09b448aa 390 Gene3D G3DSA:3.20.20.80 30 379 6.6E-13 T 29-03-2018 CSW12_RS11575 6a2b1601c29c925bbb3e5ead09b448aa 390 SUPERFAMILY SSF51445 86 364 1.58E-14 T 29-03-2018 IPR017853 Glycoside hydrolase superfamily CSW12_RS28320 dc53dcb1b46dfc2ca107c18ee7df8696 222 Gene3D G3DSA:1.10.3720.10 8 222 5.3E-36 T 29-03-2018 CSW12_RS28320 dc53dcb1b46dfc2ca107c18ee7df8696 222 SUPERFAMILY SSF161098 13 206 4.19E-43 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28320 dc53dcb1b46dfc2ca107c18ee7df8696 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 205 9.3E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS18290 1ff371db2c1ba3c9a1eece0862f2ffce 139 Gene3D G3DSA:3.10.180.10 3 134 3.1E-26 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS18290 1ff371db2c1ba3c9a1eece0862f2ffce 139 SUPERFAMILY SSF54593 3 135 9.76E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS18290 1ff371db2c1ba3c9a1eece0862f2ffce 139 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 119 4.4E-20 T 29-03-2018 CSW12_RS25695 315d58875602da1727c7768f92efe333 475 SUPERFAMILY SSF54001 359 475 4.41E-30 T 29-03-2018 CSW12_RS25695 315d58875602da1727c7768f92efe333 475 Pfam PF00877 NlpC/P60 family 374 472 1.8E-21 T 29-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CSW12_RS25695 315d58875602da1727c7768f92efe333 475 Gene3D G3DSA:3.90.1720.10 360 475 1.8E-26 T 29-03-2018 CSW12_RS25695 315d58875602da1727c7768f92efe333 475 Gene3D G3DSA:1.20.120.330 52 159 1.1E-7 T 29-03-2018 CSW12_RS25695 315d58875602da1727c7768f92efe333 475 Gene3D G3DSA:1.20.5.730 216 301 0.058 T 29-03-2018 CSW12_RS04220 d3e24d847809746e5a267ef54a61e4da 227 Gene3D G3DSA:1.20.5.170 16 97 0.0015 T 29-03-2018 CSW12_RS23025 120ee44bd60c0c0202adab1d60d2460a 90 Pfam PF13055 Protein of unknown function (DUF3917) 18 88 5.0E-48 T 29-03-2018 IPR025027 Protein of unknown function DUF3917 CSW12_RS28185 f7b21159537eb672460d1cc7bc1ed686 254 Pfam PF01522 Polysaccharide deacetylase 52 175 9.6E-26 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS28185 f7b21159537eb672460d1cc7bc1ed686 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 1.1E-84 T 29-03-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB CSW12_RS28185 f7b21159537eb672460d1cc7bc1ed686 254 Gene3D G3DSA:3.20.20.370 47 254 6.4E-49 T 29-03-2018 CSW12_RS28185 f7b21159537eb672460d1cc7bc1ed686 254 SUPERFAMILY SSF88713 14 243 6.67E-54 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS23685 1bd5e3d9539d9a4ac60f3415291f055e 76 Pfam PF13129 Protein of unknown function (DUF3953) 32 72 6.4E-12 T 29-03-2018 IPR025018 Protein of unknown function DUF3953 CSW12_RS20920 dc29b4476d7336b172bb355e35253a6f 57 Pfam PF10958 Protein of unknown function (DUF2759) 6 55 3.0E-24 T 29-03-2018 IPR024490 Protein of unknown function DUF2759 CSW12_RS20920 dc29b4476d7336b172bb355e35253a6f 57 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 1 54 7.0E-13 T 29-03-2018 IPR024490 Protein of unknown function DUF2759 CSW12_RS09900 3ed86d4fc3ac29f51104ef6a87dc7e52 114 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 4 111 7.9E-35 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 CSW12_RS09795 4b0c5a28ecd5efffe87e5b3c21af3710 268 Pfam PF12679 ABC-2 family transporter protein 28 266 4.1E-13 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CSW12_RS03675 0641ae7f5f9cf647e93aa10f2d228663 186 Pfam PF08006 Protein of unknown function (DUF1700) 1 184 6.0E-64 T 29-03-2018 IPR012963 Protein of unknown function DUF1700 CSW12_RS26105 9a7d9363ab9b1ce98d13eba85d55b5be 480 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 51 456 1.1E-25 T 29-03-2018 CSW12_RS26105 9a7d9363ab9b1ce98d13eba85d55b5be 480 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 6 471 2.6E-136 T 29-03-2018 IPR029468 O-antigen polysaccharide polymerase Wzy CSW12_RS08980 430d630037434b2b18dc9ae6559f7447 329 Pfam PF00388 Phosphatidylinositol-specific phospholipase C, X domain 59 194 1.9E-14 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain CSW12_RS08980 430d630037434b2b18dc9ae6559f7447 329 Gene3D G3DSA:3.20.20.190 34 325 1.5E-52 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS08980 430d630037434b2b18dc9ae6559f7447 329 SMART SM00148 50 194 2.1E-59 T 29-03-2018 IPR000909 Phosphatidylinositol-specific phospholipase C, X domain CSW12_RS08980 430d630037434b2b18dc9ae6559f7447 329 SUPERFAMILY SSF51695 33 324 8.89E-63 T 29-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CSW12_RS22835 a1f4cfea172744929ca088dd030418fc 212 Pfam PF11167 Protein of unknown function (DUF2953) 121 173 1.5E-19 T 29-03-2018 IPR021338 Protein of unknown function DUF2953 CSW12_RS18960 1d3795cb7ea2c72e8aea3f689f2acb6b 140 Pfam PF06713 Bacterial PH domain 54 128 5.7E-20 T 29-03-2018 IPR009589 Sublancin immunity protein SunI GO:0030153 CSW12_RS16320 53b0109b85da7cd3ddebfc9d0335748c 70 ProSitePatterns PS01309 Uncharacterized protein family UPF0057 signature. 4 19 - T 29-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 CSW12_RS16320 53b0109b85da7cd3ddebfc9d0335748c 70 Pfam PF01679 Proteolipid membrane potential modulator 2 45 9.9E-12 T 29-03-2018 IPR000612 Proteolipid membrane potential modulator GO:0016021 CSW12_RS24850 5c2139784f01a36a7f5da5e334e23e8f 81 ProDom PD065427 YUSU IG COIL COILED BH3491 1 80 9.0E-41 T 29-03-2018 IPR020393 Uncharacterised protein family YusU CSW12_RS24850 5c2139784f01a36a7f5da5e334e23e8f 81 Gene3D G3DSA:1.25.10.10 1 80 6.6E-4 T 29-03-2018 IPR011989 Armadillo-like helical CSW12_RS24850 5c2139784f01a36a7f5da5e334e23e8f 81 Pfam PF10835 Protein of unknown function (DUF2573) 3 80 7.3E-41 T 29-03-2018 IPR020393 Uncharacterised protein family YusU CSW12_RS29065 d7b0cd6d732d4068a838ae22c1bf3b78 269 Pfam PF13700 Domain of unknown function (DUF4158) 4 165 1.0E-31 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS05810 5c3b1904f9736faca5d929b33459e225 136 Pfam PF13048 Protein of unknown function (DUF3908) 4 126 4.1E-50 T 29-03-2018 IPR025020 Protein of unknown function DUF3908 CSW12_RS16590 f0013ed7b79b81de89373fbc2932108f 178 Pfam PF03358 NADPH-dependent FMN reductase 1 136 7.8E-32 T 29-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CSW12_RS16590 f0013ed7b79b81de89373fbc2932108f 178 SUPERFAMILY SSF52218 1 160 1.27E-37 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS16590 f0013ed7b79b81de89373fbc2932108f 178 Gene3D G3DSA:3.40.50.360 1 174 2.9E-33 T 29-03-2018 IPR029039 Flavoprotein-like domain CSW12_RS22910 ef0f5e4add4c2a9d687cddb218c4ad34 159 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 29-03-2018 IPR000614 Free Met sulfoxide reductase conserved site CSW12_RS22910 ef0f5e4add4c2a9d687cddb218c4ad34 159 Pfam PF13185 GAF domain 50 154 6.2E-12 T 29-03-2018 IPR003018 GAF domain GO:0005515 CSW12_RS22910 ef0f5e4add4c2a9d687cddb218c4ad34 159 Gene3D G3DSA:3.30.450.40 3 158 9.3E-26 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS22910 ef0f5e4add4c2a9d687cddb218c4ad34 159 SUPERFAMILY SSF55781 11 155 5.23E-46 T 29-03-2018 IPR029016 GAF domain-like CSW12_RS29325 575ca2c1fe9c52b9d85ac5230a755f52 156 SUPERFAMILY SSF52980 33 138 5.36E-12 T 29-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CSW12_RS29325 575ca2c1fe9c52b9d85ac5230a755f52 156 Gene3D G3DSA:3.40.960.10 40 150 1.3E-19 T 29-03-2018 CSW12_RS29325 575ca2c1fe9c52b9d85ac5230a755f52 156 Pfam PF04480 Protein of unknown function (DUF559) 65 130 3.9E-7 T 29-03-2018 IPR007569 Domain of unknown function DUF559 CSW12_RS12790 ce4ec10b8166aa02223fab81a5a2e09a 120 Gene3D G3DSA:2.60.120.10 4 117 1.4E-21 T 29-03-2018 IPR014710 RmlC-like jelly roll fold CSW12_RS12790 ce4ec10b8166aa02223fab81a5a2e09a 120 SUPERFAMILY SSF51182 23 103 2.67E-24 T 29-03-2018 IPR011051 RmlC-like cupin domain CSW12_RS12790 ce4ec10b8166aa02223fab81a5a2e09a 120 Pfam PF07883 Cupin domain 30 99 1.7E-19 T 29-03-2018 IPR013096 Cupin 2, conserved barrel CSW12_RS16260 9b97bc09488e487ce9ad9382862308b1 210 Pfam PF01810 LysE type translocator 14 206 1.2E-38 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS16260 9b97bc09488e487ce9ad9382862308b1 210 PIRSF PIRSF006324 1 209 1.5E-62 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS07970 22ffb478814c01dc918bef84b3d20ff2 100 Pfam PF14036 YlaH-like protein 16 91 1.3E-32 T 29-03-2018 IPR025620 YlaH-like protein CSW12_RS14165 5d4e190618770c6b4f43dd9e79c08153 187 SUPERFAMILY SSF55729 5 175 2.89E-22 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS14165 5d4e190618770c6b4f43dd9e79c08153 187 Gene3D G3DSA:3.40.630.30 1 182 2.4E-16 T 29-03-2018 CSW12_RS14165 5d4e190618770c6b4f43dd9e79c08153 187 Pfam PF00583 Acetyltransferase (GNAT) family 44 152 1.5E-9 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS19440 f61f61ff2c7ccfe3c8c2a407e51f32ce 277 Pfam PF01618 MotA/TolQ/ExbB proton channel family 121 237 8.0E-23 T 29-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CSW12_RS19440 f61f61ff2c7ccfe3c8c2a407e51f32ce 277 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 29-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CSW12_RS21890 91db80e8afb7017b7b00109a45f771f7 283 PIRSF PIRSF038471 2 283 2.2E-64 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CSW12_RS21890 91db80e8afb7017b7b00109a45f771f7 283 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 7 277 1.3E-59 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CSW12_RS21890 91db80e8afb7017b7b00109a45f771f7 283 Pfam PF04085 rod shape-determining protein MreC 123 273 5.5E-43 T 29-03-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 CSW12_RS27165 01e9682a989c557caf9ad52cb0dfad57 438 Pfam PF07435 YycH protein 4 414 1.5E-70 T 29-03-2018 IPR009996 Regulatory protein YycH CSW12_RS13740 f22afbd4c74e28ada78a218f8da93abd 278 SUPERFAMILY SSF161098 87 270 3.66E-38 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS13740 f22afbd4c74e28ada78a218f8da93abd 278 Gene3D G3DSA:1.10.3720.10 39 278 7.5E-34 T 29-03-2018 CSW12_RS13740 f22afbd4c74e28ada78a218f8da93abd 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 266 1.1E-23 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS08955 81104ad0d3ba207f10b02d0b35be32fd 639 Gene3D G3DSA:3.40.720.10 240 548 9.6E-45 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS08955 81104ad0d3ba207f10b02d0b35be32fd 639 Pfam PF00884 Sulfatase 248 538 5.4E-38 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CSW12_RS08955 81104ad0d3ba207f10b02d0b35be32fd 639 PIRSF PIRSF005091 1 623 3.5E-172 T 29-03-2018 IPR012160 Lipoteichoic acid synthase-like CSW12_RS08955 81104ad0d3ba207f10b02d0b35be32fd 639 SUPERFAMILY SSF53649 246 619 1.55E-72 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS19170 d0bcec98f405a2962e891f25134888aa 194 Pfam PF01738 Dienelactone hydrolase family 3 192 1.7E-17 T 29-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CSW12_RS19170 d0bcec98f405a2962e891f25134888aa 194 Gene3D G3DSA:3.40.50.1820 2 194 8.3E-11 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS19170 d0bcec98f405a2962e891f25134888aa 194 SUPERFAMILY SSF53474 4 192 8.86E-22 T 29-03-2018 IPR029058 Alpha/Beta hydrolase fold CSW12_RS01875 15978c407caa7789a7c1e49a8feca66d 368 Pfam PF03845 Spore germination protein 7 319 1.0E-56 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS01875 15978c407caa7789a7c1e49a8feca66d 368 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 360 3.9E-54 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS06380 20b439f65fb68a53070b0ff1ffe4f7d6 132 Pfam PF07179 SseB protein N-terminal domain 9 120 1.0E-14 T 29-03-2018 IPR009839 SseB protein N-terminal domain CSW12_RS09105 ae04158eed89ad62d734a97c02981689 335 Pfam PF01032 FecCD transport family 18 327 1.1E-83 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS09105 ae04158eed89ad62d734a97c02981689 335 SUPERFAMILY SSF81345 7 327 7.59E-78 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS09105 ae04158eed89ad62d734a97c02981689 335 Gene3D G3DSA:1.10.3470.10 2 335 2.6E-62 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS17305 7cb9199e12ded81a2ea9f9cebc4f258e 742 SMART SM00460 472 549 1.4E-19 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS17305 7cb9199e12ded81a2ea9f9cebc4f258e 742 Gene3D G3DSA:3.90.260.10 410 611 2.5E-27 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS17305 7cb9199e12ded81a2ea9f9cebc4f258e 742 SUPERFAMILY SSF54001 351 664 3.71E-54 T 29-03-2018 CSW12_RS17305 7cb9199e12ded81a2ea9f9cebc4f258e 742 Pfam PF01841 Transglutaminase-like superfamily 423 547 7.2E-27 T 29-03-2018 IPR002931 Transglutaminase-like CSW12_RS17305 7cb9199e12ded81a2ea9f9cebc4f258e 742 Pfam PF13559 Domain of unknown function (DUF4129) 657 712 4.3E-6 T 29-03-2018 IPR025403 Domain of unknown function DUF4129 CSW12_RS09110 f5acb74a54d84c22f009f7b1f2b84080 340 SUPERFAMILY SSF81345 7 337 1.83E-76 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS09110 f5acb74a54d84c22f009f7b1f2b84080 340 Pfam PF01032 FecCD transport family 19 337 2.3E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS09110 f5acb74a54d84c22f009f7b1f2b84080 340 Gene3D G3DSA:1.10.3470.10 4 340 3.1E-64 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS25975 2a908e1c9921a45660bc51a47d377314 516 Gene3D G3DSA:1.20.1070.10 100 499 0.0046 T 29-03-2018 CSW12_RS25770 803ca60934f3730af729a0d210e15e6f 107 PIRSF PIRSF000699 1 107 2.1E-41 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS25770 803ca60934f3730af729a0d210e15e6f 107 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 100 3.5E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS25770 803ca60934f3730af729a0d210e15e6f 107 SUPERFAMILY SSF46973 1 101 1.07E-37 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS25770 803ca60934f3730af729a0d210e15e6f 107 Gene3D G3DSA:1.20.58.80 3 101 1.8E-38 T 29-03-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 CSW12_RS29330 4a9e4b0e6ffa08753b5b437932785a32 73 Gene3D G3DSA:1.10.260.40 7 73 1.5E-9 T 29-03-2018 CSW12_RS29330 4a9e4b0e6ffa08753b5b437932785a32 73 Pfam PF01381 Helix-turn-helix 10 59 5.8E-9 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS29330 4a9e4b0e6ffa08753b5b437932785a32 73 SUPERFAMILY SSF47413 5 57 4.28E-8 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS29000 31695def7beeb109789e981c109a208e 306 Pfam PF00892 EamA-like transporter family 149 284 4.5E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS29000 31695def7beeb109789e981c109a208e 306 Pfam PF00892 EamA-like transporter family 2 136 3.2E-23 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS29000 31695def7beeb109789e981c109a208e 306 SUPERFAMILY SSF103481 186 286 6.93E-14 T 29-03-2018 CSW12_RS29000 31695def7beeb109789e981c109a208e 306 SUPERFAMILY SSF103481 37 140 1.9E-14 T 29-03-2018 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 Pfam PF01235 Sodium:alanine symporter family 55 449 2.4E-149 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 PRINTS PR00175 Sodium/alanine symporter signature 211 230 1.8E-54 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 PRINTS PR00175 Sodium/alanine symporter signature 92 114 1.8E-54 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 PRINTS PR00175 Sodium/alanine symporter signature 306 324 1.8E-54 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 PRINTS PR00175 Sodium/alanine symporter signature 409 429 1.8E-54 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 PRINTS PR00175 Sodium/alanine symporter signature 183 201 1.8E-54 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 PRINTS PR00175 Sodium/alanine symporter signature 350 372 1.8E-54 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS16125 b8475c164ec996d75c0fc41be0d24073 455 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 6.6E-159 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS23630 d797f93a9c997626e196253b5dc34fa5 325 Gene3D G3DSA:3.40.190.10 20 126 2.6E-15 T 29-03-2018 CSW12_RS23630 d797f93a9c997626e196253b5dc34fa5 325 Gene3D G3DSA:3.40.190.10 127 323 1.1E-32 T 29-03-2018 CSW12_RS23630 d797f93a9c997626e196253b5dc34fa5 325 Pfam PF13379 NMT1-like family 24 255 8.5E-28 T 29-03-2018 CSW12_RS23630 d797f93a9c997626e196253b5dc34fa5 325 SUPERFAMILY SSF53850 22 249 2.91E-34 T 29-03-2018 CSW12_RS14940 4e4391d929fb8ea7582807631e22f491 224 Pfam PF13021 Domain of unknown function (DUF3885) 182 219 3.0E-15 T 29-03-2018 IPR024976 Domain of unknown function DUF3885 CSW12_RS23855 7cf2a939017eaf5557ed1fc066befbf6 199 Pfam PF09335 SNARE associated Golgi protein 31 155 9.0E-24 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS01535 53d6133aa1e403d722d62d340f064dde 87 Gene3D G3DSA:3.40.630.30 1 75 6.2E-4 T 29-03-2018 CSW12_RS22380 d079cb9e5de1cd43e8c177abbcc88efb 179 Pfam PF02674 Colicin V production protein 2 159 5.4E-34 T 29-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CSW12_RS09015 373075e26b46d0ac9cf50595244c2180 141 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 132 5.3E-62 T 29-03-2018 IPR019723 Uncharacterised protein, YfmQ CSW12_RS30805 9288708331632f6fdb36ce090f7054b8 347 Gene3D G3DSA:1.10.287.500 23 338 2.9E-4 T 29-03-2018 CSW12_RS30805 9288708331632f6fdb36ce090f7054b8 347 Pfam PF08378 Nuclease-related domain 117 250 3.3E-12 T 29-03-2018 IPR011528 Nuclease-related domain, NERD CSW12_RS24585 6bef6e170f3e7546403d8f4331f960e4 370 Pfam PF11202 Phosphoribosyl transferase (PRTase) 9 257 5.2E-110 T 29-03-2018 IPR011215 Phosphoribosyl transferase CSW12_RS24585 6bef6e170f3e7546403d8f4331f960e4 370 Pfam PF15608 PELOTA RNA binding domain 284 364 6.0E-36 T 29-03-2018 IPR028157 PELOTA RNA-binding domain CSW12_RS24585 6bef6e170f3e7546403d8f4331f960e4 370 PIRSF PIRSF020979 1 363 8.3E-92 T 29-03-2018 IPR011215 Phosphoribosyl transferase CSW12_RS26260 39957167f6e36376c09fcb76f545fa23 366 SUPERFAMILY SSF56762 16 365 1.44E-118 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26260 39957167f6e36376c09fcb76f545fa23 366 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 3 366 47.008 T 29-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26260 39957167f6e36376c09fcb76f545fa23 366 Gene3D G3DSA:1.10.645.10 2 200 1.3E-50 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26260 39957167f6e36376c09fcb76f545fa23 366 Gene3D G3DSA:1.10.645.10 201 358 3.6E-35 T 29-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26260 39957167f6e36376c09fcb76f545fa23 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 291 365 2.9E-25 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26260 39957167f6e36376c09fcb76f545fa23 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 291 1.5E-68 T 29-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS14960 e95691b282e1a58ad276006443f7fe48 338 SUPERFAMILY SSF56601 4 284 8.54E-52 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS14960 e95691b282e1a58ad276006443f7fe48 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 114 131 2.7E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS14960 e95691b282e1a58ad276006443f7fe48 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 2.7E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS14960 e95691b282e1a58ad276006443f7fe48 338 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 154 2.7E-11 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS14960 e95691b282e1a58ad276006443f7fe48 338 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 33 266 4.8E-55 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS14960 e95691b282e1a58ad276006443f7fe48 338 Gene3D G3DSA:3.40.710.10 26 300 9.2E-29 T 29-03-2018 CSW12_RS04550 57c2fcbbaa2e00a4448fa32121e7c5ca 403 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 382 8.8E-126 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CSW12_RS04550 57c2fcbbaa2e00a4448fa32121e7c5ca 403 PIRSF PIRSF037259 1 403 1.4E-138 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CSW12_RS26860 93abcc90112206cc1eebad7a9e516685 67 Pfam PF04328 Selenoprotein, putative 4 67 1.2E-22 T 29-03-2018 IPR007423 Selenoprotein, putative CSW12_RS18025 7b9ac110543c51fa29e511b2bd79d7fb 212 Gene3D G3DSA:2.30.110.10 28 189 2.7E-27 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS18025 7b9ac110543c51fa29e511b2bd79d7fb 212 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 16 212 3.7E-80 T 29-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CSW12_RS18025 7b9ac110543c51fa29e511b2bd79d7fb 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 37 131 4.7E-13 T 29-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CSW12_RS18025 7b9ac110543c51fa29e511b2bd79d7fb 212 SUPERFAMILY SSF50475 26 180 5.43E-20 T 29-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CSW12_RS05605 039341433b7fcde88e87259a13a84796 226 SUPERFAMILY SSF53448 19 221 7.16E-10 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS05605 039341433b7fcde88e87259a13a84796 226 Pfam PF13712 Glycosyltransferase like family 8 219 1.2E-82 T 29-03-2018 CSW12_RS05605 039341433b7fcde88e87259a13a84796 226 Gene3D G3DSA:3.90.550.10 13 212 9.9E-4 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS16050 b498b9f84336e4d3730ee90407efed1a 309 Gene3D G3DSA:3.90.245.10 1 309 4.9E-61 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS16050 b498b9f84336e4d3730ee90407efed1a 309 SUPERFAMILY SSF53590 1 305 4.84E-78 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS16050 b498b9f84336e4d3730ee90407efed1a 309 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 1 298 4.2E-43 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS09455 693d7fbfae82b5f4b3468799d56b08f9 143 ProDom PD086666 YNEK BH2332 11 143 2.0E-63 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK CSW12_RS09455 693d7fbfae82b5f4b3468799d56b08f9 143 Pfam PF11084 Protein of unknown function (DUF2621) 3 141 7.4E-76 T 29-03-2018 IPR020203 Uncharacterised protein family, YneK CSW12_RS26925 2b92c64a6740cad9ec21d5bec76bb2fd 470 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 324 448 3.4E-9 T 29-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CSW12_RS26925 2b92c64a6740cad9ec21d5bec76bb2fd 470 Pfam PF01943 Polysaccharide biosynthesis protein 6 267 6.2E-14 T 29-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CSW12_RS07320 06c35db6b700373004e6b58b59bdc630 32 Pfam PF16951 Putative methionine and alanine importer, small subunit 1 29 5.2E-9 T 29-03-2018 IPR031596 Putative methionine and alanine importer, small subunit CSW12_RS17785 0ebfbd23eddc4deaa07164354085b85c 151 Pfam PF13075 Protein of unknown function (DUF3939) 10 140 4.3E-45 T 29-03-2018 IPR025071 Protein of unknown function DUF3939 CSW12_RS04335 51f8452f058ced14753ffe6a4a1f79d4 176 Pfam PF11181 Heat induced stress protein YflT 8 60 2.1E-7 T 29-03-2018 IPR025889 General stress protein 17M-like domain CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 686 5.5E-67 T 29-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 Gene3D G3DSA:3.90.1310.10 29 321 2.4E-36 T 29-03-2018 CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 Pfam PF03717 Penicillin-binding Protein dimerisation domain 60 306 1.1E-38 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 Gene3D G3DSA:3.40.710.10 322 703 7.2E-78 T 29-03-2018 CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 SUPERFAMILY SSF56601 322 692 5.83E-67 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 SUPERFAMILY SSF56519 57 118 1.06E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS15090 52e53c0935a9ede7902da5c179bdd3be 710 SUPERFAMILY SSF56519 191 321 1.06E-37 T 29-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CSW12_RS13225 f3a1c257b31ce608588fa33e6d2935bc 261 SUPERFAMILY SSF53335 29 256 3.01E-42 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS13225 f3a1c257b31ce608588fa33e6d2935bc 261 Pfam PF08241 Methyltransferase domain 46 142 2.2E-21 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS13225 f3a1c257b31ce608588fa33e6d2935bc 261 Gene3D G3DSA:3.40.50.150 27 260 3.7E-38 T 29-03-2018 CSW12_RS17650 ad67c005b1d6c8db253a8fb363995705 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 25 2.9E-14 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS17650 ad67c005b1d6c8db253a8fb363995705 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 27 2.3E-13 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS20345 b891610bb4a6638948ab1f0288ea05f7 135 Gene3D G3DSA:1.20.1050.10 20 131 0.0013 T 29-03-2018 CSW12_RS20345 b891610bb4a6638948ab1f0288ea05f7 135 PIRSF PIRSF021328 1 135 2.7E-45 T 29-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CSW12_RS20345 b891610bb4a6638948ab1f0288ea05f7 135 Pfam PF11208 Protein of unknown function (DUF2992) 3 135 1.0E-38 T 29-03-2018 IPR016787 Uncharacterised conserved protein UCP021328 CSW12_RS06925 a976363c2a814447523a0a109bc1f3a2 163 Pfam PF13047 Protein of unknown function (DUF3907) 10 157 7.7E-63 T 29-03-2018 IPR025013 Protein of unknown function DUF3907 CSW12_RS08285 ab981058959d4a613e653f0e439b4535 109 PIRSF PIRSF026544 1 109 1.0E-49 T 29-03-2018 IPR016841 Transcription regulator DksA-related, predicted CSW12_RS01615 dc2fed1266002b157cad87be5b6160f1 174 Pfam PF16167 Domain of unknown function (DUF4871) 44 171 1.5E-84 T 29-03-2018 IPR032366 Protein of unknown function DUF4871 CSW12_RS05085 ee39160712e0195884a01c67068cfcbf 182 Pfam PF07352 Bacteriophage Mu Gam like protein 30 181 8.4E-27 T 29-03-2018 IPR009951 Host-nuclease inhibitor protein Gam GO:0003690|GO:0042262 CSW12_RS05085 ee39160712e0195884a01c67068cfcbf 182 SUPERFAMILY SSF161266 22 139 3.66E-15 T 29-03-2018 CSW12_RS27220 b5aa7129f183592e4f4a8329a2100c81 311 Pfam PF09991 Predicted membrane protein (DUF2232) 15 301 2.2E-80 T 29-03-2018 IPR018710 Protein of unknown function DUF2232 CSW12_RS00080 e595c920747b320863d074241920c888 392 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 20 377 1.5E-84 T 29-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CSW12_RS00080 e595c920747b320863d074241920c888 392 SUPERFAMILY SSF103473 4 380 1.44E-47 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS00080 e595c920747b320863d074241920c888 392 Gene3D G3DSA:1.20.1250.20 3 196 2.1E-23 T 29-03-2018 CSW12_RS00080 e595c920747b320863d074241920c888 392 Gene3D G3DSA:1.20.1250.20 197 381 6.8E-20 T 29-03-2018 CSW12_RS09835 44dd02a7078bea7e8acf9f7bafb3fa63 131 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 7 48 4.0E-17 T 29-03-2018 CSW12_RS10090 3130bb92a614f07fbb4e7f4ae325ad62 303 Pfam PF04294 VanW like protein 172 299 3.7E-45 T 29-03-2018 IPR007391 Vancomycin resistance VanW CSW12_RS09365 bdcda54769c02415c9cf233dd5bcd50e 336 Pfam PF08378 Nuclease-related domain 149 276 8.6E-7 T 29-03-2018 IPR011528 Nuclease-related domain, NERD CSW12_RS21065 5ddb0893946422373955f7d046eb6d1f 118 Gene3D G3DSA:1.10.760.10 49 118 7.5E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS21065 5ddb0893946422373955f7d046eb6d1f 118 SUPERFAMILY SSF46626 5 116 5.47E-16 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS21065 5ddb0893946422373955f7d046eb6d1f 118 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 47 114 3.4E-11 T 29-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CSW12_RS21065 5ddb0893946422373955f7d046eb6d1f 118 PIRSF PIRSF000025 1 118 5.5E-42 T 29-03-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 CSW12_RS26780 c6520585a90fac2d5c38e6dac6f8bb38 330 Pfam PF12679 ABC-2 family transporter protein 6 328 5.3E-24 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CSW12_RS19905 9eb4713311de54710db02ecc68c7ac32 129 Pfam PF13473 Cupredoxin-like domain 14 128 7.1E-23 T 29-03-2018 IPR028096 EfeO-type cupredoxin-like domain CSW12_RS19905 9eb4713311de54710db02ecc68c7ac32 129 SUPERFAMILY SSF49503 34 128 3.23E-15 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS19905 9eb4713311de54710db02ecc68c7ac32 129 Gene3D G3DSA:2.60.40.420 30 129 1.4E-13 T 29-03-2018 IPR008972 Cupredoxin CSW12_RS14065 4346ca7c36dd412951c5668f4c15f7ec 476 Pfam PF02687 FtsX-like permease family 342 468 9.7E-13 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS18715 e7e7e926c2b28f3886d7dff8d8ea80ac 424 Pfam PF07690 Major Facilitator Superfamily 44 285 1.7E-16 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS18715 e7e7e926c2b28f3886d7dff8d8ea80ac 424 Gene3D G3DSA:1.20.1250.20 238 423 3.2E-20 T 29-03-2018 CSW12_RS18715 e7e7e926c2b28f3886d7dff8d8ea80ac 424 Gene3D G3DSA:1.20.1250.20 15 214 1.9E-24 T 29-03-2018 CSW12_RS18715 e7e7e926c2b28f3886d7dff8d8ea80ac 424 SUPERFAMILY SSF103473 19 421 2.35E-48 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS18995 41cb8e1b00adb01b6b4985ef85babcf6 325 Pfam PF03773 Predicted permease 42 317 1.4E-68 T 29-03-2018 IPR005524 Predicted permease DUF318 CSW12_RS00410 2b6536d8562a9884ee2abfa892918bb8 275 Gene3D G3DSA:1.10.10.10 32 163 2.6E-7 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS00410 2b6536d8562a9884ee2abfa892918bb8 275 Pfam PF13730 Helix-turn-helix domain 42 96 3.2E-8 T 29-03-2018 CSW12_RS14210 0690ad29fb343313047f9e857f64ba41 282 SUPERFAMILY SSF52151 2 273 2.17E-46 T 29-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CSW12_RS14210 0690ad29fb343313047f9e857f64ba41 282 Gene3D G3DSA:3.40.1090.10 1 262 1.1E-34 T 29-03-2018 CSW12_RS14210 0690ad29fb343313047f9e857f64ba41 282 Pfam PF01734 Patatin-like phospholipase 5 169 3.1E-19 T 29-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CSW12_RS15330 99d42ed7914ee650709c3ffd1868c8d0 167 Pfam PF13042 Protein of unknown function (DUF3902) 2 161 1.3E-38 T 29-03-2018 IPR025001 Protein of unknown function DUF3902 CSW12_RS07560 4198ff40efdd1e8b9435c4d01aa5d300 205 Gene3D G3DSA:3.40.390.10 20 192 2.0E-5 T 29-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CSW12_RS15340 c3ffeb25d68280e105255650c53042ea 66 Gene3D G3DSA:3.40.50.1100 5 59 3.8E-6 T 29-03-2018 CSW12_RS14410 205884f52987e878b02880bf81b77474 208 Pfam PF04892 VanZ like family 42 183 1.2E-27 T 29-03-2018 IPR006976 VanZ-like CSW12_RS11775 83a9353b66b71ecb12216995dafbaf4c 275 Gene3D G3DSA:2.40.50.110 167 251 7.7E-4 T 29-03-2018 CSW12_RS22170 7d5a53c063bc56e8a40600b55eff6909 148 SUPERFAMILY SSF54637 15 147 2.59E-34 T 29-03-2018 IPR029069 HotDog domain CSW12_RS22170 7d5a53c063bc56e8a40600b55eff6909 148 Gene3D G3DSA:3.10.129.10 17 147 4.3E-30 T 29-03-2018 CSW12_RS22170 7d5a53c063bc56e8a40600b55eff6909 148 Pfam PF03061 Thioesterase superfamily 33 118 5.1E-15 T 29-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CSW12_RS06955 c156ba009d8170022be8d41a127fec3d 173 Hamap MF_01319 Thiol-disulfide oxidoreductase ResA [resA]. 1 173 46.307 T 29-03-2018 IPR023555 Thiol-disulphide oxidoreductase ResA GO:0005886|GO:0015036|GO:0017004 CSW12_RS06955 c156ba009d8170022be8d41a127fec3d 173 Pfam PF00578 AhpC/TSA family 37 153 7.8E-37 T 29-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CSW12_RS06955 c156ba009d8170022be8d41a127fec3d 173 Gene3D G3DSA:3.40.30.10 29 170 1.3E-44 T 29-03-2018 CSW12_RS06955 c156ba009d8170022be8d41a127fec3d 173 SUPERFAMILY SSF52833 9 170 6.84E-46 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS08040 c92d344d815567a364a5a78e7d73aecc 207 Gene3D G3DSA:1.20.120.80 21 206 3.9E-51 T 29-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08040 c92d344d815567a364a5a78e7d73aecc 207 SUPERFAMILY SSF81452 21 204 3.01E-56 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS08040 c92d344d815567a364a5a78e7d73aecc 207 Pfam PF00510 Cytochrome c oxidase subunit III 28 204 8.0E-20 T 29-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CSW12_RS03920 a6d4a2008b2a890f99bbe9b7933ebfb9 108 SUPERFAMILY SSF101386 12 89 4.49E-9 T 29-03-2018 CSW12_RS03920 a6d4a2008b2a890f99bbe9b7933ebfb9 108 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 29 83 9.6E-6 T 29-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CSW12_RS03920 a6d4a2008b2a890f99bbe9b7933ebfb9 108 Gene3D G3DSA:1.10.287.1080 9 99 3.1E-7 T 29-03-2018 CSW12_RS20745 8bfeb760066b2020e532762aa38b03fa 264 ProDom PD123329 YQHG BH2818 1 257 5.0E-152 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG CSW12_RS20745 8bfeb760066b2020e532762aa38b03fa 264 Pfam PF11079 Bacterial protein YqhG of unknown function 1 257 6.6E-127 T 29-03-2018 IPR024562 Uncharacterised protein family YqhG CSW12_RS30300 9580325f7559b019146745506625f9e6 355 Pfam PF04235 Protein of unknown function (DUF418) 193 350 1.2E-25 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CSW12_RS05000 19b16c1dc56e712699e9d9065427cecb 68 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 68 3.0E-21 T 29-03-2018 IPR024255 Spore germination GerPB CSW12_RS05000 19b16c1dc56e712699e9d9065427cecb 68 Pfam PF10803 Spore germination GerPB 1 48 5.4E-24 T 29-03-2018 IPR024255 Spore germination GerPB CSW12_RS00965 e0fcc411b49af4a62df0b5748991ea7c 226 Pfam PF07947 YhhN family 51 222 2.4E-28 T 29-03-2018 IPR012506 YhhN-like GO:0016021 CSW12_RS15940 f53c5d555c0f716cc6d3d1ab93768617 61 Pfam PF14169 Cold-inducible protein YdjO 4 60 2.2E-28 T 29-03-2018 IPR025916 Cold-inducible protein YdjO CSW12_RS29155 abc172ed4ac435e32f100993866f0ea5 86 SUPERFAMILY SSF103642 63 81 1.52E-5 T 29-03-2018 CSW12_RS19650 cc13fc226a0858ce0f409e7a8db909ac 212 Pfam PF02397 Bacterial sugar transferase 27 206 3.1E-64 T 29-03-2018 IPR003362 Bacterial sugar transferase CSW12_RS27415 7d129e77e5dda0d699b3ec158e4888d9 179 Pfam PF00857 Isochorismatase family 4 165 6.9E-29 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS27415 7d129e77e5dda0d699b3ec158e4888d9 179 Gene3D G3DSA:3.40.50.850 1 178 2.7E-34 T 29-03-2018 CSW12_RS27415 7d129e77e5dda0d699b3ec158e4888d9 179 SUPERFAMILY SSF52499 2 176 1.83E-44 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS14235 8997c771e398d9aac18736fa6734b170 271 Pfam PF09234 Domain of unknown function (DUF1963) 42 270 8.9E-67 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 CSW12_RS14235 8997c771e398d9aac18736fa6734b170 271 SUPERFAMILY SSF103032 7 270 1.01E-85 T 29-03-2018 IPR015315 Protein of unknown function DUF1963 CSW12_RS14235 8997c771e398d9aac18736fa6734b170 271 Gene3D G3DSA:2.30.320.10 3 271 1.0E-70 T 29-03-2018 CSW12_RS08005 3d11e53ea68de64e985292881eef79c0 392 Pfam PF01098 Cell cycle protein 13 368 1.1E-106 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CSW12_RS08005 3d11e53ea68de64e985292881eef79c0 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 325 349 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CSW12_RS09485 a755d8c6811c0c2c5c0930d6e7414f81 146 SUPERFAMILY SSF111064 7 146 1.31E-62 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CSW12_RS09485 a755d8c6811c0c2c5c0930d6e7414f81 146 Pfam PF09021 HutP 9 144 3.0E-38 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CSW12_RS09485 a755d8c6811c0c2c5c0930d6e7414f81 146 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 146 45.628 T 29-03-2018 IPR023552 Hut operon regulatory protein HutP, bacillales CSW12_RS09485 a755d8c6811c0c2c5c0930d6e7414f81 146 Gene3D G3DSA:3.40.1510.10 6 146 1.2E-47 T 29-03-2018 IPR015111 Hut operon regulatory protein HutP CSW12_RS14725 549464ccd71a385ec27f4647ab7758f0 197 SUPERFAMILY SSF55729 11 185 1.19E-27 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS14725 549464ccd71a385ec27f4647ab7758f0 197 Gene3D G3DSA:3.40.630.30 9 192 2.9E-15 T 29-03-2018 CSW12_RS14725 549464ccd71a385ec27f4647ab7758f0 197 Pfam PF13302 Acetyltransferase (GNAT) domain 17 169 1.0E-20 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS12060 dc399a501a2febdefb991a84e1b843aa 193 Gene3D G3DSA:1.10.10.10 1 94 6.9E-19 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12060 dc399a501a2febdefb991a84e1b843aa 193 SUPERFAMILY SSF46785 3 173 5.17E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12060 dc399a501a2febdefb991a84e1b843aa 193 Pfam PF03551 Transcriptional regulator PadR-like family 7 82 3.3E-10 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS02465 088fe06dd0ce1c74e6133e468643e4c0 381 Pfam PF04860 Phage portal protein 36 354 5.9E-37 T 29-03-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein CSW12_RS02465 088fe06dd0ce1c74e6133e468643e4c0 381 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 32 360 2.9E-50 T 29-03-2018 IPR006427 Phage portal protein, HK97 CSW12_RS04630 85e3ef5c2549376c395b1b81e7639bda 250 Pfam PF10014 2OG-Fe dioxygenase 55 243 2.3E-38 T 29-03-2018 IPR018724 2OG-Fe dioxygenase CSW12_RS25150 1128c0c0b33366e80bb586ae7d12d0d4 146 Pfam PF07849 Protein of unknown function (DUF1641) 107 128 7.0E-5 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CSW12_RS28905 6506124bdfd6df634da4cd065ebd6d1c 243 SUPERFAMILY SSF52833 1 212 2.76E-45 T 29-03-2018 IPR012336 Thioredoxin-like fold CSW12_RS28905 6506124bdfd6df634da4cd065ebd6d1c 243 Pfam PF01323 DSBA-like thioredoxin domain 2 206 7.5E-43 T 29-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CSW12_RS28905 6506124bdfd6df634da4cd065ebd6d1c 243 Gene3D G3DSA:3.40.30.10 1 217 9.3E-51 T 29-03-2018 CSW12_RS21010 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 Gene3D G3DSA:1.10.10.10 6 92 9.3E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS21010 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 Pfam PF01475 Ferric uptake regulator family 12 129 3.4E-28 T 29-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CSW12_RS21010 3b2d156b81c6462e3cd7ac4e8c12dcdd 137 SUPERFAMILY SSF46785 5 133 8.71E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS17940 fca8a7ceca03994c2acae3448da48334 91 Gene3D G3DSA:1.10.1200.10 4 91 2.7E-9 T 29-03-2018 CSW12_RS17940 fca8a7ceca03994c2acae3448da48334 91 SUPERFAMILY SSF47336 1 81 3.45E-11 T 29-03-2018 IPR009081 Phosphopantetheine binding ACP domain CSW12_RS02655 7a878769f0882030726b51d076575819 573 Pfam PF10101 Predicted membrane protein (DUF2339) 384 564 1.9E-10 T 29-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CSW12_RS02655 7a878769f0882030726b51d076575819 573 Pfam PF10101 Predicted membrane protein (DUF2339) 96 408 6.3E-29 T 29-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CSW12_RS20185 855bffc9be3bf65f4ed8fc2ec891eec1 183 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 16 168 1.5E-21 T 29-03-2018 IPR018639 Domain of unknown function DUF2062 CSW12_RS13240 9e23eac9ee2764ca3006ab24ff4ef54b 80 Pfam PF04226 Transglycosylase associated protein 31 75 2.2E-11 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CSW12_RS05400 f60c9d1d64e2dcc999db50a9460ba11d 58 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 1 58 4.0E-26 T 29-03-2018 IPR024558 ComZ CSW12_RS05400 f60c9d1d64e2dcc999db50a9460ba11d 58 Pfam PF10815 ComZ 3 57 1.7E-32 T 29-03-2018 IPR024558 ComZ CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 SUPERFAMILY SSF52540 73 360 6.82E-73 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 Pfam PF00270 DEAD/DEAH box helicase 29 196 1.7E-50 T 29-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 SMART SM00487 24 222 7.0E-62 T 29-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 Gene3D G3DSA:3.40.50.300 3 224 4.6E-58 T 29-03-2018 CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 SMART SM00490 258 339 2.7E-34 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 Pfam PF00271 Helicase conserved C-terminal domain 241 339 8.8E-30 T 29-03-2018 IPR001650 Helicase, C-terminal CSW12_RS15690 c2317e8047854861df0b94dc527f930c 458 Gene3D G3DSA:3.40.50.300 225 456 5.1E-46 T 29-03-2018 CSW12_RS16515 79b1e6a5b370dadc3293c8b66238d080 249 Pfam PF14344 Domain of unknown function (DUF4397) 61 173 7.4E-28 T 29-03-2018 IPR025510 Domain of unknown function DUF4397 CSW12_RS16515 79b1e6a5b370dadc3293c8b66238d080 249 Pfam PF14344 Domain of unknown function (DUF4397) 172 248 7.9E-8 T 29-03-2018 IPR025510 Domain of unknown function DUF4397 CSW12_RS24835 353bd60928725b129a02978035873347 48 Pfam PF14115 YuzL-like protein 3 42 1.7E-17 T 29-03-2018 IPR025625 YuzL-like protein CSW12_RS27105 25ab5e22e7c78047a4979ccd77e06422 186 Pfam PF08876 Domain of unknown function (DUF1836) 19 123 4.6E-31 T 29-03-2018 IPR014975 Protein of unknown function DUF1836 CSW12_RS10595 d30b5a02cb4367397a23c075f26bc080 116 SUPERFAMILY SSF89442 8 116 2.22E-52 T 29-03-2018 IPR014934 Protein of unknown function DUF1806 CSW12_RS10595 d30b5a02cb4367397a23c075f26bc080 116 Gene3D G3DSA:2.70.180.10 1 115 1.0E-51 T 29-03-2018 IPR014934 Protein of unknown function DUF1806 CSW12_RS10595 d30b5a02cb4367397a23c075f26bc080 116 Pfam PF08830 Protein of unknown function (DUF1806) 8 115 5.8E-53 T 29-03-2018 IPR014934 Protein of unknown function DUF1806 CSW12_RS24100 4009fe16976c9ed7ce47d94c71b7f244 201 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 44 1.9E-10 T 29-03-2018 IPR023833 Signal peptide, camelysin CSW12_RS24100 4009fe16976c9ed7ce47d94c71b7f244 201 Pfam PF12389 Camelysin metallo-endopeptidase 2 199 3.5E-83 T 29-03-2018 IPR022121 Peptidase M73, camelysin CSW12_RS11120 232a4cd955fde251ceb24f6725f5bf09 79 Pfam PF13061 Protein of unknown function (DUF3923) 5 68 4.0E-25 T 29-03-2018 IPR025037 Protein of unknown function DUF3923 CSW12_RS09670 963c2e5a02fd20396339bfd6830a0782 49 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 49 21.674 T 29-03-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 CSW12_RS09670 963c2e5a02fd20396339bfd6830a0782 49 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 49 2.1E-29 T 29-03-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 CSW12_RS09670 963c2e5a02fd20396339bfd6830a0782 49 Pfam PF08175 Small acid-soluble spore protein O family 3 49 1.9E-24 T 29-03-2018 CSW12_RS09670 963c2e5a02fd20396339bfd6830a0782 49 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 38 6.0E-14 T 29-03-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 CSW12_RS12675 afc6c0eb02c6a8c92e3362f948a67dd0 160 Pfam PF11188 Protein of unknown function (DUF2975) 32 160 3.6E-40 T 29-03-2018 IPR021354 Protein of unknown function DUF2975 CSW12_RS18125 2f51219dfb6782a170376708eb258bc7 376 Gene3D G3DSA:3.40.640.10 12 241 4.3E-29 T 29-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CSW12_RS18125 2f51219dfb6782a170376708eb258bc7 376 Gene3D G3DSA:3.90.1150.10 242 376 3.0E-23 T 29-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CSW12_RS18125 2f51219dfb6782a170376708eb258bc7 376 PIRSF PIRSF000390 1 375 3.8E-70 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CSW12_RS18125 2f51219dfb6782a170376708eb258bc7 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 366 1.0E-67 T 29-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CSW12_RS18125 2f51219dfb6782a170376708eb258bc7 376 SUPERFAMILY SSF53383 17 364 1.09E-61 T 29-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CSW12_RS11030 859fb9dd9dafb6698df8889ab811d3e9 441 PIRSF PIRSF002746 1 441 7.0E-145 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS11030 859fb9dd9dafb6698df8889ab811d3e9 441 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 5 441 4.3E-137 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS11030 859fb9dd9dafb6698df8889ab811d3e9 441 Pfam PF02447 GntP family permease 5 439 7.0E-145 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS09700 a6f7aae9bdc3c238bd4c719f254a2901 47 Pfam PF13040 Fur-regulated basic protein B 2 40 2.7E-17 T 29-03-2018 IPR025004 Transcriptional regulatory protein SenN/SenS CSW12_RS09280 aadcce5697ffdb1e54f20004a3b5bfed 107 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 1.4E-21 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS09280 aadcce5697ffdb1e54f20004a3b5bfed 107 Gene3D G3DSA:1.10.10.10 2 107 1.6E-26 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS09280 aadcce5697ffdb1e54f20004a3b5bfed 107 SUPERFAMILY SSF46785 10 103 6.3E-25 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS10370 640be058cb77148f9437420a9282acd9 132 Pfam PF11070 Protein of unknown function (DUF2871) 1 128 5.4E-37 T 29-03-2018 IPR021299 Protein of unknown function DUF2871 CSW12_RS27145 e477346b3aad0170e55aeb67f6f5b225 61 Pfam PF14116 YyzF-like protein 5 52 9.8E-21 T 29-03-2018 IPR025626 YyzF-like protein CSW12_RS27145 e477346b3aad0170e55aeb67f6f5b225 61 TIGRFAM TIGR04129 CxxH_BA5709: CxxH/CxxC protein, BA_5709 family 4 51 3.2E-20 T 29-03-2018 IPR025626 YyzF-like protein CSW12_RS08405 f454d53125566c0918199934725c94d3 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 2.9E-42 T 29-03-2018 IPR013527 YicC-like, N-terminal CSW12_RS08405 f454d53125566c0918199934725c94d3 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 5.5E-89 T 29-03-2018 IPR005229 Conserved hypothetical protein CHP00255 CSW12_RS08405 f454d53125566c0918199934725c94d3 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 6.4E-38 T 29-03-2018 IPR013551 Domain of unknown function DUF1732 CSW12_RS24640 90834d1f61f1fc0bb39935a2befb18f7 192 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 12 164 2.6E-21 T 29-03-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like CSW12_RS21545 3ccdf2ef776378070a902321a62a5676 309 Pfam PF01136 Peptidase family U32 75 306 1.8E-70 T 29-03-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 CSW12_RS21545 3ccdf2ef776378070a902321a62a5676 309 Gene3D G3DSA:3.20.20.70 4 284 2.9E-6 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS06660 cc277edc432cfe68aed77ea423fc89bf 233 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 11 168 5.6E-40 T 29-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CSW12_RS06660 cc277edc432cfe68aed77ea423fc89bf 233 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 3.5E-13 T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS06660 cc277edc432cfe68aed77ea423fc89bf 233 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 29-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CSW12_RS28810 0465b824fedf0bd8ba81357c700c849c 157 Gene3D G3DSA:3.40.50.300 1 151 2.3E-47 T 29-03-2018 CSW12_RS28810 0465b824fedf0bd8ba81357c700c849c 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 135 1.0E-40 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CSW12_RS28810 0465b824fedf0bd8ba81357c700c849c 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 132 4.8E-38 T 29-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CSW12_RS28810 0465b824fedf0bd8ba81357c700c849c 157 SUPERFAMILY SSF52540 25 120 1.06E-20 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS22010 65de769a0863353a8a141867a8ffa8a9 332 Gene3D G3DSA:1.25.40.10 1 321 6.6E-10 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS22010 65de769a0863353a8a141867a8ffa8a9 332 SUPERFAMILY SSF48452 15 212 1.03E-6 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS25440 c18b8ef40a6561511c75bbd81b9b3fc0 289 Pfam PF07870 Protein of unknown function (DUF1657) 240 283 1.8E-15 T 29-03-2018 IPR012452 Protein of unknown function DUF1657 CSW12_RS25440 c18b8ef40a6561511c75bbd81b9b3fc0 289 Pfam PF04239 Protein of unknown function (DUF421) 92 206 5.4E-32 T 29-03-2018 IPR007353 Protein of unknown function DUF421 CSW12_RS25440 c18b8ef40a6561511c75bbd81b9b3fc0 289 Gene3D G3DSA:3.30.240.20 85 154 6.4E-24 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS25440 c18b8ef40a6561511c75bbd81b9b3fc0 289 Gene3D G3DSA:3.30.240.20 168 229 9.3E-12 T 29-03-2018 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CSW12_RS19495 948db221b80a4dcc55d3b707a8a0caf5 105 Pfam PF09685 Domain of unknown function (DUF4870) 6 101 1.4E-7 T 29-03-2018 IPR019109 Protein of unknown function DUF4870 CSW12_RS19495 948db221b80a4dcc55d3b707a8a0caf5 105 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 105 7.0E-53 T 29-03-2018 CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 18 137 7.3E-25 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 Gene3D G3DSA:3.40.80.10 1 157 7.8E-35 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF00395 S-layer homology domain 168 207 7.5E-8 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF00395 S-layer homology domain 222 265 3.7E-11 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 Pfam PF00395 S-layer homology domain 286 328 5.5E-4 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 SUPERFAMILY SSF55846 3 154 7.46E-44 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS03715 505730e2d67b331b07d0f02f2c6b9c4b 340 SMART SM00644 8 153 4.4E-24 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS05695 cddf483c92df5103f99541d30fc788e4 222 Pfam PF14329 Domain of unknown function (DUF4386) 12 217 1.3E-41 T 29-03-2018 IPR025495 Protein of unknown function DUF4386 CSW12_RS02220 70c7a94a47ee8a01756960a4f5f67a01 404 Gene3D G3DSA:1.20.1170.10 127 346 0.0022 T 29-03-2018 CSW12_RS02220 70c7a94a47ee8a01756960a4f5f67a01 404 Gene3D G3DSA:1.20.5.50 3 108 3.7E-4 T 29-03-2018 CSW12_RS06280 6fbfcd5b05fb0b5e3e9ba06daf5b3273 200 Gene3D G3DSA:3.40.50.1240 1 198 1.2E-8 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS06280 6fbfcd5b05fb0b5e3e9ba06daf5b3273 200 SUPERFAMILY SSF53254 51 192 1.03E-14 T 29-03-2018 IPR029033 Histidine phosphatase superfamily CSW12_RS25530 abd4274b2d032b2476e01d5ce35572bb 143 Pfam PF14275 Domain of unknown function (DUF4362) 30 122 8.9E-38 T 29-03-2018 IPR025372 Protein of unknown function DUF4362 CSW12_RS20065 9cb8d892f38ce2f0a8b5502a5365ed1d 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 1.0E-30 T 29-03-2018 IPR020076 Protein of unknown function DUF2768 CSW12_RS20065 9cb8d892f38ce2f0a8b5502a5365ed1d 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 1.7E-24 T 29-03-2018 IPR020076 Protein of unknown function DUF2768 CSW12_RS16910 ae19c773c4d5e9cfb2f6c731d91254d6 75 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 9 71 6.7E-24 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS16910 ae19c773c4d5e9cfb2f6c731d91254d6 75 SUPERFAMILY SSF47413 3 72 1.91E-19 T 29-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CSW12_RS16910 ae19c773c4d5e9cfb2f6c731d91254d6 75 SMART SM00530 9 65 2.2E-6 T 29-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CSW12_RS16910 ae19c773c4d5e9cfb2f6c731d91254d6 75 Gene3D G3DSA:1.10.260.40 2 75 2.9E-11 T 29-03-2018 CSW12_RS09610 7d03f90e899b7de6159adba92c1c2a28 191 Pfam PF02632 BioY family 29 171 8.4E-36 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CSW12_RS09610 7d03f90e899b7de6159adba92c1c2a28 191 PIRSF PIRSF016661 1 179 4.7E-48 T 29-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CSW12_RS03250 5350c7ca06747e1ae7e70e9e7786357a 254 Pfam PF01925 Sulfite exporter TauE/SafE 7 247 2.7E-41 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS22610 0db01db8bd7deb0ae850d245b4bd34b0 372 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 5.1E-125 T 29-03-2018 IPR014227 Sporulation integral membrane protein YtvI CSW12_RS22610 0db01db8bd7deb0ae850d245b4bd34b0 372 Pfam PF01594 AI-2E family transporter 12 354 4.1E-69 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CSW12_RS30245 4e75f1d087a940ea782b5d2f88ca3a8d 993 Pfam PF13700 Domain of unknown function (DUF4158) 7 172 3.3E-53 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS30245 4e75f1d087a940ea782b5d2f88ca3a8d 993 Pfam PF01526 Tn3 transposase DDE domain 583 968 1.8E-141 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 CSW12_RS29540 4e75f1d087a940ea782b5d2f88ca3a8d 993 Pfam PF13700 Domain of unknown function (DUF4158) 7 172 3.3E-53 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS29540 4e75f1d087a940ea782b5d2f88ca3a8d 993 Pfam PF01526 Tn3 transposase DDE domain 583 968 1.8E-141 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 CSW12_RS26700 e6ef86cb16650934c1509375b32803a9 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 5.9E-11 T 29-03-2018 IPR009910 Protein of unknown function DUF1450 CSW12_RS26700 e6ef86cb16650934c1509375b32803a9 74 Hamap MF_01863 UPF0741 protein . 1 74 28.737 T 29-03-2018 IPR020880 Protein of unknown function UPF0741 CSW12_RS23680 dce3c8ac0d4d506c21dc5c4e149588c7 76 Pfam PF13129 Protein of unknown function (DUF3953) 33 69 3.1E-9 T 29-03-2018 IPR025018 Protein of unknown function DUF3953 CSW12_RS16940 3e6057e80607ca392a733db2e725ba3f 479 Pfam PF02447 GntP family permease 65 270 2.8E-8 T 29-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CSW12_RS23710 46e5c45a136bd76b850353ae0d2c01ab 449 PIRSF PIRSF006446 1 448 3.8E-173 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CSW12_RS23710 46e5c45a136bd76b850353ae0d2c01ab 449 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 433 9.0E-175 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CSW12_RS15680 da86067c5b6a28c409ae91881ff6ea53 135 PIRSF PIRSF500687 1 135 8.7E-70 T 29-03-2018 IPR027259 Predicted 3-demethylubiquinone-9 3-methyltransferase, bacterial CSW12_RS15680 da86067c5b6a28c409ae91881ff6ea53 135 Gene3D G3DSA:3.10.180.10 3 135 3.4E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS15680 da86067c5b6a28c409ae91881ff6ea53 135 PIRSF PIRSF021700 3 135 2.2E-44 T 29-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CSW12_RS15680 da86067c5b6a28c409ae91881ff6ea53 135 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 132 2.7E-44 T 29-03-2018 IPR028973 PhnB-like CSW12_RS15680 da86067c5b6a28c409ae91881ff6ea53 135 SUPERFAMILY SSF54593 6 132 8.62E-40 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS00800 9568de36de55906f21ff4c53f4911c19 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 257 4.9E-26 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS00800 9568de36de55906f21ff4c53f4911c19 265 Gene3D G3DSA:1.10.3720.10 14 258 2.8E-23 T 29-03-2018 CSW12_RS00800 9568de36de55906f21ff4c53f4911c19 265 SUPERFAMILY SSF161098 61 246 1.14E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS03910 8e4d0b099ec092d39bacc6c29bd3f738 133 Pfam PF00293 NUDIX domain 7 124 8.5E-18 T 29-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CSW12_RS03910 8e4d0b099ec092d39bacc6c29bd3f738 133 SUPERFAMILY SSF55811 2 126 1.62E-31 T 29-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CSW12_RS03910 8e4d0b099ec092d39bacc6c29bd3f738 133 Gene3D G3DSA:3.90.79.10 1 131 4.2E-28 T 29-03-2018 CSW12_RS03910 8e4d0b099ec092d39bacc6c29bd3f738 133 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.0E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS03910 8e4d0b099ec092d39bacc6c29bd3f738 133 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.0E-6 T 29-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CSW12_RS05495 c749eca42eac5e0cddb5d8d5916b3d70 227 PIRSF PIRSF029008 1 225 6.0E-78 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS05495 c749eca42eac5e0cddb5d8d5916b3d70 227 Hamap MF_01124 Adapter protein MecA [mecA]. 1 223 27.465 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS05495 c749eca42eac5e0cddb5d8d5916b3d70 227 Pfam PF05389 Negative regulator of genetic competence (MecA) 2 219 2.3E-48 T 29-03-2018 IPR008681 Negative regulator of genetic competence, MecA CSW12_RS07930 fdf66a54bf61ed3cd982c8975125c8f4 276 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 247 55.485 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CSW12_RS07930 fdf66a54bf61ed3cd982c8975125c8f4 276 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 24 238 1.0E-124 T 29-03-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 CSW12_RS07060 218483749acb9412fac48e9624f26b4c 176 Gene3D G3DSA:3.40.80.10 3 174 1.6E-32 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS07060 218483749acb9412fac48e9624f26b4c 176 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 151 5.1E-19 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS07060 218483749acb9412fac48e9624f26b4c 176 SMART SM00644 15 151 4.1E-15 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS07060 218483749acb9412fac48e9624f26b4c 176 SUPERFAMILY SSF55846 15 168 7.59E-34 T 29-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CSW12_RS06055 e7e37a3eb0c068da62db14e49c89b655 239 Pfam PF02754 Cysteine-rich domain 3 83 3.7E-18 T 29-03-2018 IPR004017 Cysteine-rich domain CSW12_RS06055 e7e37a3eb0c068da62db14e49c89b655 239 Pfam PF02754 Cysteine-rich domain 132 215 2.6E-15 T 29-03-2018 IPR004017 Cysteine-rich domain CSW12_RS06055 e7e37a3eb0c068da62db14e49c89b655 239 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 62.853 T 29-03-2018 IPR022822 Lactate utilization protein A GO:0006089 CSW12_RS19545 4fd112f2c24f0d549e977a01b54bfd0b 209 Pfam PF04116 Fatty acid hydroxylase superfamily 42 183 5.4E-18 T 29-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CSW12_RS13415 59cf651d1abe0e1934b6c0a35b4018ea 198 Gene3D G3DSA:3.40.50.880 5 196 2.7E-52 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS13415 59cf651d1abe0e1934b6c0a35b4018ea 198 SUPERFAMILY SSF52317 6 193 8.1E-51 T 29-03-2018 IPR029062 Class I glutamine amidotransferase-like CSW12_RS13415 59cf651d1abe0e1934b6c0a35b4018ea 198 Pfam PF01965 DJ-1/PfpI family 7 175 3.4E-30 T 29-03-2018 IPR002818 DJ-1/PfpI CSW12_RS16630 4da3bb9a7163e09fc2a2fb76ebe3b515 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 303 1.5E-7 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16630 4da3bb9a7163e09fc2a2fb76ebe3b515 349 SUPERFAMILY SSF161098 86 282 9.81E-10 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS16630 4da3bb9a7163e09fc2a2fb76ebe3b515 349 Gene3D G3DSA:1.10.3720.10 11 308 1.4E-19 T 29-03-2018 CSW12_RS13830 cf677119e840f0dd21ac9e91b2fc4e73 200 Pfam PF13649 Methyltransferase domain 40 129 1.9E-13 T 29-03-2018 CSW12_RS13830 cf677119e840f0dd21ac9e91b2fc4e73 200 Gene3D G3DSA:3.40.50.150 1 181 8.5E-20 T 29-03-2018 CSW12_RS13830 cf677119e840f0dd21ac9e91b2fc4e73 200 SUPERFAMILY SSF53335 3 170 4.26E-27 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS19105 86524686f421ad9a5d5684e3b85cefc9 148 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 131 5.7E-62 T 29-03-2018 IPR019723 Uncharacterised protein, YfmQ CSW12_RS01870 14b0e943ab22eca34fbe26b72bf8cb06 374 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 201 371 7.3E-31 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS01870 14b0e943ab22eca34fbe26b72bf8cb06 374 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 373 3.0E-92 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS04435 158c9249fe9b034ed5568aefd6ef8c25 66 Pfam PF14147 Sporulation protein YhaL 4 55 5.6E-29 T 29-03-2018 IPR025428 Sporulation protein YhaL CSW12_RS12665 b02743e36648b93deb726d57db28deac 282 SUPERFAMILY SSF52540 3 129 5.13E-7 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12665 b02743e36648b93deb726d57db28deac 282 SUPERFAMILY SSF52540 1 46 9.82E-6 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS12665 b02743e36648b93deb726d57db28deac 282 Gene3D G3DSA:3.40.50.300 5 178 1.8E-10 T 29-03-2018 CSW12_RS00930 b17dc852a81e40f240a746e3a3c4f3fa 74 Hamap MF_00829 UPF0435 protein . 6 73 20.475 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 CSW12_RS00930 b17dc852a81e40f240a746e3a3c4f3fa 74 Pfam PF06569 Protein of unknown function (DUF1128) 3 71 8.9E-32 T 29-03-2018 IPR009507 Protein of unknown function UPF0435 CSW12_RS09340 704b8f6e864c8d843c39cc795a62f939 146 Pfam PF10747 Sporulation inhibitor of replication protein SirA 2 140 5.6E-42 T 29-03-2018 IPR019683 Sporulation inhibitor of replication protein SirA CSW12_RS28545 db370c9ba0d616883a8fa9a4d5eae808 253 Pfam PF16285 Domain of unknown function (DUF4931) 8 251 2.3E-123 T 29-03-2018 CSW12_RS28545 db370c9ba0d616883a8fa9a4d5eae808 253 SUPERFAMILY SSF54197 13 129 6.99E-23 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS28545 db370c9ba0d616883a8fa9a4d5eae808 253 PIRSF PIRSF031505 1 253 1.5E-129 T 29-03-2018 IPR012361 Galactose-1-phosphate uridylyltransferase, short form, putative CSW12_RS28545 db370c9ba0d616883a8fa9a4d5eae808 253 Gene3D G3DSA:3.30.428.10 56 131 1.2E-12 T 29-03-2018 IPR011146 HIT-like domain GO:0003824 CSW12_RS27510 6e7b83337fbff2fae3e20142ddd8229b 121 Pfam PF06156 Initiation control protein YabA 7 116 2.3E-37 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CSW12_RS27510 6e7b83337fbff2fae3e20142ddd8229b 121 Hamap MF_01159 Initiation-control protein YabA. 6 120 25.571 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CSW12_RS27510 6e7b83337fbff2fae3e20142ddd8229b 121 PIRSF PIRSF021439 6 121 1.9E-42 T 29-03-2018 IPR010377 Initiation control protein YabA GO:0006260 CSW12_RS27510 6e7b83337fbff2fae3e20142ddd8229b 121 Gene3D G3DSA:1.10.287.510 12 120 6.2E-5 T 29-03-2018 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 SUPERFAMILY SSF54001 2 254 2.94E-64 T 29-03-2018 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 Pfam PF00797 N-acetyltransferase 22 255 2.7E-43 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 45 68 3.0E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 102 127 3.0E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 21 44 3.0E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 PRINTS PR01543 Arylamine N-acetyltransferase signature 69 91 3.0E-7 T 29-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 Gene3D G3DSA:3.30.2140.10 132 255 1.9E-7 T 29-03-2018 CSW12_RS14110 30cefedde4ba9def57daf4c2b011eb04 255 Gene3D G3DSA:3.30.2140.10 3 131 2.7E-26 T 29-03-2018 CSW12_RS12760 c3f57c8e6e8d536770b66083085de219 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 303 318 2.0E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12760 c3f57c8e6e8d536770b66083085de219 347 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 271 286 2.0E-5 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12760 c3f57c8e6e8d536770b66083085de219 347 SUPERFAMILY SSF46785 268 345 3.76E-16 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12760 c3f57c8e6e8d536770b66083085de219 347 Gene3D G3DSA:1.10.10.10 258 341 1.2E-13 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS12760 c3f57c8e6e8d536770b66083085de219 347 SMART SM00418 269 342 5.4E-9 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12760 c3f57c8e6e8d536770b66083085de219 347 Pfam PF01022 Bacterial regulatory protein, arsR family 276 320 5.3E-12 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS12235 f3116d7fd908e5d238b197854eaa0f5e 155 Pfam PF10903 Protein of unknown function (DUF2691) 2 153 2.4E-58 T 29-03-2018 IPR020216 Uncharacterised protein family, YncE CSW12_RS12235 f3116d7fd908e5d238b197854eaa0f5e 155 ProDom PD091678 YNCE 1 154 1.0E-74 T 29-03-2018 IPR020216 Uncharacterised protein family, YncE CSW12_RS17760 12e6e981477a90f08749c87d5e1b7efc 194 Gene3D G3DSA:3.40.630.30 9 191 2.2E-21 T 29-03-2018 CSW12_RS17760 12e6e981477a90f08749c87d5e1b7efc 194 SUPERFAMILY SSF55729 10 185 2.56E-40 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS17760 12e6e981477a90f08749c87d5e1b7efc 194 Pfam PF13302 Acetyltransferase (GNAT) domain 16 159 3.1E-25 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS17090 209b21ec1157f67364d7256a0224e359 258 Pfam PF04445 Putative SAM-dependent methyltransferase 42 250 1.4E-16 T 29-03-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 CSW12_RS17090 209b21ec1157f67364d7256a0224e359 258 Gene3D G3DSA:3.40.50.150 68 256 8.9E-20 T 29-03-2018 CSW12_RS17090 209b21ec1157f67364d7256a0224e359 258 SUPERFAMILY SSF53335 2 256 1.86E-54 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS27365 c2b36c6394bbd28a65683d35cfda8345 333 Pfam PF14175 YaaC-like Protein 11 321 6.7E-112 T 29-03-2018 IPR026988 YaaC-like protein CSW12_RS03120 5a8225ebe274eeda9dfd9963145fc5cf 505 PIRSF PIRSF005690 6 496 8.2E-134 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS03120 5a8225ebe274eeda9dfd9963145fc5cf 505 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 25 481 6.3E-148 T 29-03-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 CSW12_RS28585 a4fb9df7af83ea47e8cd43aea672d025 307 Gene3D G3DSA:1.10.3720.10 1 294 1.0E-43 T 29-03-2018 CSW12_RS28585 a4fb9df7af83ea47e8cd43aea672d025 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 305 1.5E-40 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS28585 a4fb9df7af83ea47e8cd43aea672d025 307 SUPERFAMILY SSF161098 78 288 2.88E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS21870 973d302fd92bbc925f9f79a9c9ada924 248 Pfam PF01551 Peptidase family M23 148 241 1.7E-21 T 29-03-2018 IPR016047 Peptidase M23 CSW12_RS21870 973d302fd92bbc925f9f79a9c9ada924 248 SUPERFAMILY SSF51261 92 244 2.3E-20 T 29-03-2018 IPR011055 Duplicated hybrid motif CSW12_RS21870 973d302fd92bbc925f9f79a9c9ada924 248 Gene3D G3DSA:2.70.70.10 1 247 5.6E-25 T 29-03-2018 CSW12_RS00205 15ed82685f20a4b2bb363149d955e79e 287 SUPERFAMILY SSF52540 101 266 2.28E-15 T 29-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CSW12_RS00205 15ed82685f20a4b2bb363149d955e79e 287 Gene3D G3DSA:3.40.50.300 81 276 3.8E-11 T 29-03-2018 CSW12_RS00205 15ed82685f20a4b2bb363149d955e79e 287 Pfam PF01695 IstB-like ATP binding protein 139 258 1.5E-14 T 29-03-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 CSW12_RS01725 ae663300b7cb6016849812633676bb5f 173 Gene3D G3DSA:3.40.190.10 1 151 6.7E-4 T 29-03-2018 CSW12_RS03230 3384c652496ba4d612cc4a6b1753d8c1 76 Gene3D G3DSA:3.30.110.40 1 76 6.3E-29 T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03230 3384c652496ba4d612cc4a6b1753d8c1 76 SUPERFAMILY SSF64307 5 75 7.98E-26 T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03230 3384c652496ba4d612cc4a6b1753d8c1 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 29-03-2018 IPR001455 TusA-like domain CSW12_RS03230 3384c652496ba4d612cc4a6b1753d8c1 76 Pfam PF01206 Sulfurtransferase TusA 7 75 9.2E-25 T 29-03-2018 IPR001455 TusA-like domain CSW12_RS09895 078bc6ebfb26fa64dd7a494b0f5e3883 160 Pfam PF07849 Protein of unknown function (DUF1641) 118 155 5.1E-18 T 29-03-2018 IPR012440 Protein of unknown function DUF1641 CSW12_RS19870 aac7f1fe30bf49f625cdea83be1c47ca 167 Gene3D G3DSA:3.10.450.40 94 165 1.5E-17 T 29-03-2018 CSW12_RS19870 aac7f1fe30bf49f625cdea83be1c47ca 167 SUPERFAMILY SSF54403 94 164 4.76E-17 T 29-03-2018 CSW12_RS19870 aac7f1fe30bf49f625cdea83be1c47ca 167 SUPERFAMILY SSF54403 33 94 1.53E-17 T 29-03-2018 CSW12_RS19870 aac7f1fe30bf49f625cdea83be1c47ca 167 Pfam PF03413 Peptidase propeptide and YPEB domain 95 162 1.7E-5 T 29-03-2018 IPR025711 PepSY domain CSW12_RS19870 aac7f1fe30bf49f625cdea83be1c47ca 167 Gene3D G3DSA:3.10.450.40 26 89 3.0E-22 T 29-03-2018 CSW12_RS11885 ca7db63a7f7bcd8023273f69ff7adeea 109 Gene3D G3DSA:3.10.450.40 42 104 2.4E-7 T 29-03-2018 CSW12_RS16815 a0f4deaa0cce0da39eb0e7e6786d03ba 90 Pfam PF10751 Protein of unknown function (DUF2535) 9 90 3.0E-26 T 29-03-2018 IPR019687 Protein of unknown function DUF2535 CSW12_RS29595 ebc1028b00bf4a6b8a9fd3f755f856cd 1005 Pfam PF01526 Tn3 transposase DDE domain 597 983 2.0E-149 T 29-03-2018 IPR002513 Tn3 transposase DDE domain GO:0004803|GO:0006313 CSW12_RS29595 ebc1028b00bf4a6b8a9fd3f755f856cd 1005 Pfam PF13700 Domain of unknown function (DUF4158) 4 165 1.5E-30 T 29-03-2018 IPR025296 Domain of unknown function DUF4158 CSW12_RS30005 a4006ca3bd4cd6398723d227e4b54442 139 Gene3D G3DSA:3.10.450.50 3 123 1.9E-6 T 29-03-2018 CSW12_RS30005 a4006ca3bd4cd6398723d227e4b54442 139 SUPERFAMILY SSF54427 10 114 2.8E-7 T 29-03-2018 IPR032710 NTF2-like domain CSW12_RS06325 1a51b1b419d3c8f0f33a2bc35276ba74 133 Gene3D G3DSA:1.10.620.20 3 104 6.4E-21 T 29-03-2018 CSW12_RS06325 1a51b1b419d3c8f0f33a2bc35276ba74 133 SUPERFAMILY SSF47240 4 129 4.46E-31 T 29-03-2018 IPR009078 Ferritin-like superfamily CSW12_RS06325 1a51b1b419d3c8f0f33a2bc35276ba74 133 Pfam PF00268 Ribonucleotide reductase, small chain 3 92 3.9E-20 T 29-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CSW12_RS18000 af5cb49797ad1ae773a596a31f68a633 755 Pfam PF11308 Glycosyl hydrolases related to GH101 family, GH129 385 709 4.5E-139 T 29-03-2018 IPR021459 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 CSW12_RS19720 d8c7b6a56c0bd718cb6905565b22c64a 90 Pfam PF10752 Protein of unknown function (DUF2533) 1 83 5.0E-38 T 29-03-2018 IPR019688 Protein of unknown function DUF2533 CSW12_RS05385 8eb6da844757d209f1142c1570f504e9 60 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 1.7E-21 T 29-03-2018 IPR021324 Protein of unknown function DUF2929 CSW12_RS20980 7565fef79d3e11c84f7d5707046c8b34 425 Gene3D G3DSA:1.20.1250.20 205 396 0.0016 T 29-03-2018 CSW12_RS20980 7565fef79d3e11c84f7d5707046c8b34 425 Pfam PF07690 Major Facilitator Superfamily 20 337 7.6E-21 T 29-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CSW12_RS20980 7565fef79d3e11c84f7d5707046c8b34 425 Gene3D G3DSA:1.20.1250.20 2 200 1.3E-22 T 29-03-2018 CSW12_RS20980 7565fef79d3e11c84f7d5707046c8b34 425 SUPERFAMILY SSF103473 13 342 5.1E-29 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS06770 47fe6b67ce8729b6ad771627633677c4 246 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 131 243 2.0E-34 T 29-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CSW12_RS06770 47fe6b67ce8729b6ad771627633677c4 246 PIRSF PIRSF031509 5 246 6.3E-74 T 29-03-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 CSW12_RS03100 8ea7d1c2e0d6acdf3d20e6773e7a64c7 82 Pfam PF14148 YhdB-like protein 3 71 7.6E-38 T 29-03-2018 IPR025431 YhdB-like protein CSW12_RS04555 e4b2eb6f1df6b41f74df10f19456f7de 235 Pfam PF12787 EcsC protein family 7 232 3.9E-77 T 29-03-2018 IPR024787 EcsC protein CSW12_RS04555 e4b2eb6f1df6b41f74df10f19456f7de 235 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 1 234 3.0E-117 T 29-03-2018 CSW12_RS18950 6584464ad91c1d7e9e5c31f7bdedd40e 254 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 185 252 1.9E-28 T 29-03-2018 IPR018656 Domain of unknown function DUF2087 CSW12_RS18950 6584464ad91c1d7e9e5c31f7bdedd40e 254 Gene3D G3DSA:1.10.10.10 74 181 0.0014 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS29890 6cd36d068397ca21e48b1077b763bb7c 379 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 376 1.3E-88 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS29890 6cd36d068397ca21e48b1077b763bb7c 379 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 207 374 2.2E-29 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS15175 9a61cab1b3f4b272b78143756d63ef18 232 SUPERFAMILY SSF143548 32 149 1.44E-26 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CSW12_RS15175 9a61cab1b3f4b272b78143756d63ef18 232 Pfam PF03315 Serine dehydratase beta chain 18 92 8.4E-11 T 29-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS15175 9a61cab1b3f4b272b78143756d63ef18 232 Gene3D G3DSA:3.30.1330.90 34 161 3.0E-20 T 29-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CSW12_RS15175 9a61cab1b3f4b272b78143756d63ef18 232 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 15 169 1.2E-48 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS15175 9a61cab1b3f4b272b78143756d63ef18 232 PIRSF PIRSF036692 14 232 5.5E-57 T 29-03-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CSW12_RS01475 40fffefb29687bf316ffe80ecc479986 287 Gene3D G3DSA:3.40.630.30 6 142 0.014 T 29-03-2018 CSW12_RS01475 40fffefb29687bf316ffe80ecc479986 287 Pfam PF00583 Acetyltransferase (GNAT) family 183 275 5.3E-12 T 29-03-2018 IPR000182 GNAT domain GO:0008080 CSW12_RS01475 40fffefb29687bf316ffe80ecc479986 287 SUPERFAMILY SSF55729 153 283 1.95E-19 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS01475 40fffefb29687bf316ffe80ecc479986 287 Gene3D G3DSA:3.40.630.30 151 287 1.4E-19 T 29-03-2018 CSW12_RS20780 02973ece16d32bccd5d63f147090e7bf 123 Pfam PF14173 ComG operon protein 7 31 122 8.4E-26 T 29-03-2018 IPR020372 Competence operon G protein 7, ComGG CSW12_RS06065 ba2150a99655039d92893cbbf09147f5 236 Pfam PF02589 LUD domain 51 236 8.0E-34 T 29-03-2018 IPR003741 LUD domain CSW12_RS06065 ba2150a99655039d92893cbbf09147f5 236 Hamap MF_02104 Lactate utilization protein C [lutC]. 4 236 48.269 T 29-03-2018 IPR022823 Lactate utilization protein C CSW12_RS06065 ba2150a99655039d92893cbbf09147f5 236 SUPERFAMILY SSF100950 46 236 7.11E-39 T 29-03-2018 CSW12_RS06065 ba2150a99655039d92893cbbf09147f5 236 Gene3D G3DSA:3.40.50.10420 44 236 8.0E-41 T 29-03-2018 CSW12_RS07080 283b2bf6067f307315c61f7e60c8f5b7 57 Pfam PF17313 Family of unknown function (DUF5359) 1 56 2.3E-23 T 29-03-2018 IPR035281 Protein of unknown function DUF5359 CSW12_RS05915 320fc66edaaef6f7bfa5576b0abd3b1b 251 Pfam PF08241 Methyltransferase domain 43 130 1.1E-14 T 29-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CSW12_RS05915 320fc66edaaef6f7bfa5576b0abd3b1b 251 SUPERFAMILY SSF53335 5 243 1.14E-29 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS05915 320fc66edaaef6f7bfa5576b0abd3b1b 251 Gene3D G3DSA:3.40.50.150 2 248 1.8E-22 T 29-03-2018 CSW12_RS14310 02d68e4faba72bf5424a6c74b351f6b4 307 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 299 1.8E-64 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS14310 02d68e4faba72bf5424a6c74b351f6b4 307 Gene3D G3DSA:3.90.245.10 2 306 1.9E-74 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS14310 02d68e4faba72bf5424a6c74b351f6b4 307 SUPERFAMILY SSF53590 2 306 4.58E-80 T 29-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CSW12_RS06090 a91b83d3dd3682189ec9caf67b4f8001 439 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 28 410 1.9E-110 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CSW12_RS06090 a91b83d3dd3682189ec9caf67b4f8001 439 Pfam PF02386 Cation transport protein 17 423 1.4E-59 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CSW12_RS26820 5915dc13d4be5b3abb0acb0bc5ae672b 409 Pfam PF00654 Voltage gated chloride channel 62 398 8.3E-40 T 29-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CSW12_RS26820 5915dc13d4be5b3abb0acb0bc5ae672b 409 SUPERFAMILY SSF81340 8 399 8.11E-50 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CSW12_RS26820 5915dc13d4be5b3abb0acb0bc5ae672b 409 Gene3D G3DSA:1.10.3080.10 6 400 4.5E-44 T 29-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CSW12_RS14005 a5c66b23bab1ccdad0cc51fbd55eff92 305 Pfam PF00892 EamA-like transporter family 4 134 2.1E-17 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS14005 a5c66b23bab1ccdad0cc51fbd55eff92 305 Pfam PF00892 EamA-like transporter family 149 287 1.1E-19 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS14005 a5c66b23bab1ccdad0cc51fbd55eff92 305 SUPERFAMILY SSF103481 37 139 2.09E-14 T 29-03-2018 CSW12_RS14005 a5c66b23bab1ccdad0cc51fbd55eff92 305 SUPERFAMILY SSF103481 186 290 2.75E-16 T 29-03-2018 CSW12_RS11170 c99b741905de29299ec4ed6457605cc6 82 Pfam PF04226 Transglycosylase associated protein 33 77 1.3E-9 T 29-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CSW12_RS04340 04898b9726383cdfa2daa768c740e422 93 Pfam PF13220 Protein of unknown function (DUF4028) 27 91 3.5E-47 T 29-03-2018 IPR025106 Protein of unknown function DUF4028 CSW12_RS04900 27fa60c24e1fc55917afa0226a853d71 220 Pfam PF00395 S-layer homology domain 42 84 1.1E-10 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04900 27fa60c24e1fc55917afa0226a853d71 220 Pfam PF00395 S-layer homology domain 102 146 1.2E-10 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS04900 27fa60c24e1fc55917afa0226a853d71 220 Pfam PF00395 S-layer homology domain 162 205 6.6E-10 T 29-03-2018 IPR001119 S-layer homology domain CSW12_RS08545 69721bb0bb4826485a0b08c8da145bde 110 SUPERFAMILY SSF88659 1 102 1.23E-34 T 29-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CSW12_RS08545 69721bb0bb4826485a0b08c8da145bde 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 101 5.0E-41 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CSW12_RS08545 69721bb0bb4826485a0b08c8da145bde 110 Gene3D G3DSA:1.10.10.10 1 110 2.5E-33 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS08545 69721bb0bb4826485a0b08c8da145bde 110 Hamap MF_00245 UPF0122 protein . 2 103 22.481 T 29-03-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like CSW12_RS14290 0c0dda179bb86596de788dbb72f32447 93 TIGRFAM TIGR03601 B_an_ocin: bacteriocin, heterocycloanthracin/sonorensin family 6 91 1.0E-35 T 29-03-2018 IPR019890 Bacteriocin, heterocycloanthracin/sonorensin family CSW12_RS09870 717b35dfd0e8ff9010b76cb886b82ce4 378 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 378 1.2E-58 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS09870 717b35dfd0e8ff9010b76cb886b82ce4 378 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 199 375 2.8E-26 T 29-03-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 CSW12_RS00575 995f56cb41a83735a1242a805974c30f 335 Pfam PF01032 FecCD transport family 20 333 3.2E-86 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS00575 995f56cb41a83735a1242a805974c30f 335 Gene3D G3DSA:1.10.3470.10 5 335 7.2E-66 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS00575 995f56cb41a83735a1242a805974c30f 335 SUPERFAMILY SSF81345 5 333 2.48E-77 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS19475 d92edd144a5b792b7d546acb9c436d14 241 Pfam PF01925 Sulfite exporter TauE/SafE 8 233 3.3E-31 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS17585 2cbe0097f6429afb4225bc5e415ee98f 175 Gene3D G3DSA:1.20.120.450 2 167 4.4E-18 T 29-03-2018 CSW12_RS17585 2cbe0097f6429afb4225bc5e415ee98f 175 Pfam PF07609 Protein of unknown function (DUF1572) 3 164 2.5E-76 T 29-03-2018 IPR011466 Protein of unknown function DUF1572 CSW12_RS17585 2cbe0097f6429afb4225bc5e415ee98f 175 SUPERFAMILY SSF109854 7 150 1.23E-20 T 29-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CSW12_RS19500 c87cbd6ed3cd8075c8a232be18844cf6 194 Gene3D G3DSA:3.40.50.620 33 173 3.2E-36 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS19500 c87cbd6ed3cd8075c8a232be18844cf6 194 Pfam PF02698 DUF218 domain 44 169 6.5E-30 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CSW12_RS17720 6a17f95f518ccbc2c08852049080f072 334 Pfam PF10947 Protein of unknown function (DUF2628) 52 150 1.3E-23 T 29-03-2018 IPR024399 Protein of unknown function DUF2628 CSW12_RS07595 a4e7707a25b90bc6ecc6c6c763555290 456 SUPERFAMILY SSF56801 94 310 3.53E-6 T 29-03-2018 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 Pfam PF01494 FAD binding domain 5 367 6.9E-100 T 29-03-2018 IPR002938 FAD-binding domain GO:0071949 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 Gene3D G3DSA:3.50.50.60 1 398 5.3E-56 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 SUPERFAMILY SSF51905 91 195 3.6E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 SUPERFAMILY SSF51905 7 63 3.6E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 SUPERFAMILY SSF51905 300 373 3.6E-53 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.1E-41 T 29-03-2018 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 319 5.1E-41 T 29-03-2018 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 355 5.1E-41 T 29-03-2018 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 5.1E-41 T 29-03-2018 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 355 371 5.1E-41 T 29-03-2018 CSW12_RS10415 48120fccb1c71d5ab3a2702ec7d99c32 539 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 5.1E-41 T 29-03-2018 CSW12_RS28340 d592c0c9ef66fa0f61ab947d133d9795 254 Gene3D G3DSA:3.40.190.10 1 251 4.7E-4 T 29-03-2018 CSW12_RS14895 9b7db56047ba5d667a62a68f19490592 186 Gene3D G3DSA:3.40.50.150 25 170 1.4E-8 T 29-03-2018 CSW12_RS14895 9b7db56047ba5d667a62a68f19490592 186 SUPERFAMILY SSF53335 43 153 5.35E-10 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS16600 603a9c72331fa9223ba81319be4080a2 406 SUPERFAMILY SSF53448 15 114 4.03E-15 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS16600 603a9c72331fa9223ba81319be4080a2 406 SUPERFAMILY SSF48452 215 340 1.39E-8 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS16600 603a9c72331fa9223ba81319be4080a2 406 Gene3D G3DSA:3.90.550.10 4 179 9.4E-19 T 29-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CSW12_RS16600 603a9c72331fa9223ba81319be4080a2 406 Gene3D G3DSA:1.25.40.10 180 388 5.6E-11 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS16600 603a9c72331fa9223ba81319be4080a2 406 Pfam PF13704 Glycosyl transferase family 2 22 112 1.7E-8 T 29-03-2018 CSW12_RS14970 023d67fec4c2705c14add7fda0b1943e 45 Pfam PF13104 Protein of unknown function (DUF3956) 1 45 2.0E-33 T 29-03-2018 IPR025225 Protein of unknown function DUF3956 CSW12_RS23580 285519614375f7accf04815bd9faa484 242 Pfam PF13731 WxL domain surface cell wall-binding 28 241 2.0E-59 T 29-03-2018 IPR027994 WxL domain CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 Gene3D G3DSA:1.20.1330.10 38 264 9.2E-59 T 29-03-2018 CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 PRINTS PR00207 Flagellin signature 35 52 7.2E-21 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 PRINTS PR00207 Flagellin signature 109 132 7.2E-21 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 PRINTS PR00207 Flagellin signature 74 93 7.2E-21 T 29-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 Pfam PF00700 Bacterial flagellin C-terminal helical region 208 291 3.4E-24 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 1.1E-37 T 29-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CSW12_RS19280 2ed402a841ca33fbdc2da6a0c9ed4a92 292 SUPERFAMILY SSF64518 1 292 1.57E-86 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Pfam PF01391 Collagen triple helix repeat (20 copies) 983 1037 1.8E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Pfam PF01391 Collagen triple helix repeat (20 copies) 1031 1086 5.7E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Pfam PF01391 Collagen triple helix repeat (20 copies) 158 216 1.5E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 455 516 1.6E-15 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 804 856 1.0E-16 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 1033 1085 2.6E-14 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 580 645 2.1E-12 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 646 694 2.1E-17 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 214 269 1.3E-13 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 914 972 7.9E-17 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 973 1032 7.0E-11 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 1139 1199 7.3E-11 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 270 326 8.2E-14 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 327 388 9.4E-12 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 389 454 2.5E-16 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 517 579 1.9E-12 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 695 803 0.012 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 1086 1138 1.7E-13 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 857 913 1.4E-15 T 29-03-2018 CSW12_RS09240 b78874f298144f6175edadceb01e58b5 1318 Gene3D G3DSA:2.160.20.50 144 213 1.2E-17 T 29-03-2018 CSW12_RS03760 eb3039969ee19c60fb1e335bb8cdd155 464 Pfam PF13425 O-antigen ligase like membrane protein 10 462 3.3E-130 T 29-03-2018 CSW12_RS25805 8e35fe64cc9f647aa76913ec865a20d2 100 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 3.4E-23 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS25805 8e35fe64cc9f647aa76913ec865a20d2 100 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 93 3.3E-34 T 29-03-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CSW12_RS25805 8e35fe64cc9f647aa76913ec865a20d2 100 SUPERFAMILY SSF52794 1 98 9.68E-36 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS25805 8e35fe64cc9f647aa76913ec865a20d2 100 Gene3D G3DSA:3.40.50.2300 1 100 3.4E-38 T 29-03-2018 CSW12_RS13210 55a3063706f21e00104741aa54b2a35e 50 Pfam PF14553 YqbF, hypothetical protein domain 7 47 7.5E-17 T 29-03-2018 IPR027926 Uncharacterised protein YqbF domain CSW12_RS13210 55a3063706f21e00104741aa54b2a35e 50 Gene3D G3DSA:3.40.5.20 1 45 1.8E-25 T 29-03-2018 IPR027926 Uncharacterised protein YqbF domain CSW12_RS13210 55a3063706f21e00104741aa54b2a35e 50 SUPERFAMILY SSF160059 1 48 9.81E-20 T 29-03-2018 CSW12_RS04270 818d7ed4d6f9984cac55010876f20563 193 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 85 125 9.4E-8 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CSW12_RS04575 283ef043ac5774e1014d719ef6603fd1 158 SUPERFAMILY SSF103473 26 88 5.62E-5 T 29-03-2018 IPR020846 Major facilitator superfamily domain CSW12_RS04575 283ef043ac5774e1014d719ef6603fd1 158 Pfam PF03703 Bacterial PH domain 72 146 9.0E-15 T 29-03-2018 IPR005182 Domain of unknown function DUF304 CSW12_RS04575 283ef043ac5774e1014d719ef6603fd1 158 Gene3D G3DSA:1.20.1250.20 24 89 6.5E-4 T 29-03-2018 CSW12_RS26290 8f142abc371e327704716832696c52e9 261 Pfam PF06161 Protein of unknown function (DUF975) 4 257 5.1E-31 T 29-03-2018 IPR010380 Protein of unknown function DUF975 CSW12_RS21150 9d4532315875fad17c509950af22f7b9 210 Pfam PF14062 Domain of unknown function (DUF4253) 105 210 4.5E-33 T 29-03-2018 IPR025349 Domain of unknown function DUF4253 CSW12_RS25750 42fc61788cbc6c7102e436fc7a50974a 137 SMART SM00754 3 134 1.2E-39 T 29-03-2018 IPR010895 CHRD CSW12_RS25750 42fc61788cbc6c7102e436fc7a50974a 137 Pfam PF07452 CHRD domain 5 132 3.9E-22 T 29-03-2018 IPR010895 CHRD CSW12_RS24455 6a1907c48278f60436021791499eb40a 61 Gene3D G3DSA:3.40.50.150 4 60 2.1E-5 T 29-03-2018 CSW12_RS24455 6a1907c48278f60436021791499eb40a 61 Pfam PF01596 O-methyltransferase 18 58 1.4E-6 T 29-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CSW12_RS10780 eaa00cd26cbd458b4e70801f56a8286f 207 Pfam PF01810 LysE type translocator 12 203 2.2E-35 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS10780 eaa00cd26cbd458b4e70801f56a8286f 207 PIRSF PIRSF006324 1 206 2.8E-48 T 29-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CSW12_RS01005 2a3446a68a3f9f7fb06f8bc05b7e7810 265 Pfam PF14167 YfkD-like protein 34 263 3.2E-105 T 29-03-2018 IPR025548 YfkD-like protein CSW12_RS04595 4af2556820b07869cabd95db51eb6367 88 Pfam PF14206 Cysteine-rich CPCC 3 77 7.9E-35 T 29-03-2018 IPR025983 Cysteine-rich CPCC domain CSW12_RS19590 5a3870fb956c2b0d09ab711b1c32d761 290 Gene3D G3DSA:2.70.98.10 1 290 9.9E-64 T 29-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CSW12_RS19590 5a3870fb956c2b0d09ab711b1c32d761 290 Pfam PF01263 Aldose 1-epimerase 2 258 1.5E-33 T 29-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CSW12_RS19590 5a3870fb956c2b0d09ab711b1c32d761 290 SUPERFAMILY SSF74650 4 289 1.76E-57 T 29-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CSW12_RS01165 2f0c3d03209b1a3eb4fb3d6a66f4151d 39 Pfam PF14152 YfhE-like protein 2 37 2.5E-19 T 29-03-2018 IPR025437 YfhE-like protein CSW12_RS05355 cf0ead98d55d53633309d4e612a73bc8 65 Pfam PF12758 Protein of unknown function (DUF3813) 1 61 2.2E-28 T 29-03-2018 IPR024217 Protein of unknown function DUF3813 CSW12_RS03435 6d73bdb003954c1036d777309aa54ae5 467 PIRSF PIRSF006060 6 467 1.9E-101 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS03435 6d73bdb003954c1036d777309aa54ae5 467 Pfam PF13520 Amino acid permease 24 437 2.5E-63 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS01605 93ebf2a40e6673a5909b1088ba461d2b 448 Pfam PF03390 2-hydroxycarboxylate transporter family 32 442 2.1E-161 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 CSW12_RS01605 93ebf2a40e6673a5909b1088ba461d2b 448 PIRSF PIRSF005348 13 448 3.3E-171 T 29-03-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 CSW12_RS00520 00577c9da60f5716443a7e4a4b72b350 231 SUPERFAMILY SSF55729 18 165 9.17E-10 T 29-03-2018 IPR016181 Acyl-CoA N-acyltransferase CSW12_RS00520 00577c9da60f5716443a7e4a4b72b350 231 Gene3D G3DSA:3.40.630.30 6 202 2.1E-8 T 29-03-2018 CSW12_RS23675 2d2099f2818d2259ab5f815350c54dc8 66 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 18 61 2.9E-16 T 29-03-2018 IPR022248 TNF receptor family, RELT CSW12_RS27820 102a1d61c6e09308f2075b549ebb19cc 153 PIRSF PIRSF010607 1 153 1.1E-66 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CSW12_RS27820 102a1d61c6e09308f2075b549ebb19cc 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 5.7E-58 T 29-03-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 CSW12_RS01025 063f8cb2517a716b8ee5fad80944c903 260 Pfam PF01522 Polysaccharide deacetylase 64 185 9.2E-35 T 29-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CSW12_RS01025 063f8cb2517a716b8ee5fad80944c903 260 SUPERFAMILY SSF88713 45 255 8.9E-67 T 29-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CSW12_RS01025 063f8cb2517a716b8ee5fad80944c903 260 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 32 254 1.2E-115 T 29-03-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA CSW12_RS01025 063f8cb2517a716b8ee5fad80944c903 260 Gene3D G3DSA:3.20.20.370 27 260 3.1E-58 T 29-03-2018 CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Gene3D G3DSA:2.160.20.50 135 177 4.5E-14 T 29-03-2018 CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Gene3D G3DSA:2.160.20.50 91 134 6.1E-15 T 29-03-2018 CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Gene3D G3DSA:2.160.20.50 32 90 7.1E-16 T 29-03-2018 CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Gene3D G3DSA:2.60.120.40 178 307 2.6E-21 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Pfam PF01391 Collagen triple helix repeat (20 copies) 116 173 8.6E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Pfam PF01391 Collagen triple helix repeat (20 copies) 41 95 3.5E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS05585 ec1b1b800048b17a62d48b4227523ce5 307 Pfam PF01391 Collagen triple helix repeat (20 copies) 80 137 4.9E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS17730 9b396f4b7e67c0933f1355d4ec13c9d1 345 Gene3D G3DSA:3.20.20.70 1 343 7.8E-116 T 29-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CSW12_RS17730 9b396f4b7e67c0933f1355d4ec13c9d1 345 Hamap MF_01614 NADPH dehydrogenase [namA]. 2 338 66.824 T 29-03-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 CSW12_RS17730 9b396f4b7e67c0933f1355d4ec13c9d1 345 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 320 2.7E-90 T 29-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CSW12_RS17730 9b396f4b7e67c0933f1355d4ec13c9d1 345 SUPERFAMILY SSF51395 3 333 4.79E-113 T 29-03-2018 CSW12_RS15450 b155465b5acc4128429239154e96ea19 213 Gene3D G3DSA:3.40.1440.10 8 101 2.1E-11 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS15450 b155465b5acc4128429239154e96ea19 213 SUPERFAMILY SSF82771 21 82 1.83E-8 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS15450 b155465b5acc4128429239154e96ea19 213 SMART SM00465 20 121 0.0016 T 29-03-2018 IPR000305 GIY-YIG nuclease superfamily CSW12_RS20040 d45533abcd80d63e156fc75a3963eb37 244 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 230 6.6E-75 T 29-03-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 CSW12_RS04235 c9633413152796e8139d9be8c0d2a512 79 Pfam PF11391 Protein of unknown function (DUF2798) 15 71 5.5E-12 T 29-03-2018 IPR021529 Protein of unknown function DUF2798 CSW12_RS10895 09a6434d9c28adbd09a61a0f88a7a3e2 188 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 174 3.9E-28 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS10895 09a6434d9c28adbd09a61a0f88a7a3e2 188 Gene3D G3DSA:3.40.50.1110 1 188 1.8E-38 T 29-03-2018 CSW12_RS10895 09a6434d9c28adbd09a61a0f88a7a3e2 188 SUPERFAMILY SSF52266 1 186 2.29E-43 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS09995 b83add4d4275c7d1a4c59ffd5eb3d756 92 ProDom PD745092 MEMBRANE YHDT SODIUM/PANTOTHENATE TRANSMEMBRANE INNER SYMPORTER Y0210 INTEGRAL PROTEIN-LIKE PM1090 7 88 1.0E-40 T 29-03-2018 IPR010398 Protein of unknown function DUF997 CSW12_RS09995 b83add4d4275c7d1a4c59ffd5eb3d756 92 Pfam PF06196 Protein of unknown function (DUF997) 12 88 3.2E-32 T 29-03-2018 IPR010398 Protein of unknown function DUF997 CSW12_RS22500 46ba21f020c08a2123d027d5e2d5b563 293 PIRSF PIRSF012563 11 285 5.4E-112 T 29-03-2018 IPR014199 Sporulation protein YtxC CSW12_RS22500 46ba21f020c08a2123d027d5e2d5b563 293 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 2 267 9.4E-87 T 29-03-2018 IPR014199 Sporulation protein YtxC CSW12_RS22500 46ba21f020c08a2123d027d5e2d5b563 293 Pfam PF08812 YtxC-like family 55 267 2.8E-56 T 29-03-2018 IPR014199 Sporulation protein YtxC CSW12_RS10710 318fdb2d4990036d5ad68abf07dbe225 96 Pfam PF12650 Domain of unknown function (DUF3784) 10 93 7.4E-12 T 29-03-2018 IPR017259 Uncharacterised conserved protein UCP037672 CSW12_RS26790 2c2aeffa00a15da72b51ae34df96a042 269 Gene3D G3DSA:3.40.50.1110 49 265 2.5E-36 T 29-03-2018 CSW12_RS26790 2c2aeffa00a15da72b51ae34df96a042 269 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 61 246 2.3E-23 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS26790 2c2aeffa00a15da72b51ae34df96a042 269 SUPERFAMILY SSF52266 55 258 3.66E-38 T 29-03-2018 IPR013830 SGNH hydrolase-type esterase domain CSW12_RS00940 280489a5b525637296ab20237cc2e00f 171 Pfam PF13294 Domain of unknown function (DUF4075) 91 169 8.9E-48 T 29-03-2018 IPR025276 Protein of unknown function DUF4075 CSW12_RS12825 160f323224f789abece408aebb82454a 500 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 4 492 54.137 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CSW12_RS12825 160f323224f789abece408aebb82454a 500 SUPERFAMILY SSF51905 4 274 1.22E-22 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS12825 160f323224f789abece408aebb82454a 500 Gene3D G3DSA:3.50.50.60 1 455 4.2E-16 T 29-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CSW12_RS12825 160f323224f789abece408aebb82454a 500 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 8 490 1.2E-216 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CSW12_RS12825 160f323224f789abece408aebb82454a 500 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 7 492 2.4E-240 T 29-03-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 CSW12_RS24635 92e9c9651e88b606b1ce5c5335ba00e5 103 PIRSF PIRSF012565 1 103 7.7E-51 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 CSW12_RS24635 92e9c9651e88b606b1ce5c5335ba00e5 103 Pfam PF06265 Protein of unknown function (DUF1027) 16 99 2.1E-38 T 29-03-2018 IPR009370 Protein of unknown function DUF1027 CSW12_RS28475 c1794e914a1b7839e519709e830f8f42 317 Pfam PF00892 EamA-like transporter family 3 141 1.3E-20 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS28475 c1794e914a1b7839e519709e830f8f42 317 Pfam PF00892 EamA-like transporter family 157 291 2.4E-7 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS19460 6061c0990d415a5a6aee67fdc173d1ad 39 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 7 30 8.7E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS19460 6061c0990d415a5a6aee67fdc173d1ad 39 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 9 32 2.0E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS24325 9702889ba510c552ca2191605e4c337a 179 SUPERFAMILY SSF49329 30 169 4.45E-39 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CSW12_RS24325 9702889ba510c552ca2191605e4c337a 179 Gene3D G3DSA:2.60.40.200 17 179 6.3E-39 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CSW12_RS24325 9702889ba510c552ca2191605e4c337a 179 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 34 169 2.6E-36 T 29-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CSW12_RS12695 195ded27a786b3e74c98a48905df7b03 343 Pfam PF00487 Fatty acid desaturase 51 290 2.4E-34 T 29-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CSW12_RS15470 44a1de5d95c43a4807f609814d90b012 363 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 360 8.9E-85 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS15470 44a1de5d95c43a4807f609814d90b012 363 Pfam PF03845 Spore germination protein 8 329 1.2E-114 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS12180 e656dbc676bf187f5af2f7bf8fd9cd65 113 Pfam PF08863 YolD-like protein 21 112 1.1E-22 T 29-03-2018 IPR014962 YolD-like protein CSW12_RS21865 d8c202fbb4c76981fd265c11f0d902e9 286 Pfam PF02163 Peptidase family M50 113 167 1.4E-7 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CSW12_RS14635 8d493fb514933fe4283b16f93b4a0759 138 Pfam PF13160 Protein of unknown function (DUF3995) 12 132 6.3E-36 T 29-03-2018 IPR025058 Protein of unknown function DUF3995 CSW12_RS07810 4154d0541cad881f08f3fc545718c34d 172 Pfam PF04308 Ribonuclease H-like 20 172 3.2E-48 T 29-03-2018 IPR007405 Bacteriophage KVP40, Orf299 CSW12_RS00265 49ce6abb4803350ea2179ef03205e034 106 Gene3D G3DSA:1.10.720.10 71 105 1.4E-9 T 29-03-2018 CSW12_RS00265 49ce6abb4803350ea2179ef03205e034 106 Pfam PF07498 Rho termination factor, N-terminal domain 72 99 7.5E-8 T 29-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CSW12_RS22755 539cfafcb487c47014e266e7f1b4cd11 231 Gene3D G3DSA:1.20.1250.20 1 229 0.0012 T 29-03-2018 CSW12_RS20115 5bf90b3dd581c5d3f6d1d0cecb65998e 106 Gene3D G3DSA:1.20.1270.30 19 67 5.1E-5 T 29-03-2018 CSW12_RS20115 5bf90b3dd581c5d3f6d1d0cecb65998e 106 Gene3D G3DSA:1.20.1270.30 68 106 2.4E-4 T 29-03-2018 CSW12_RS16390 b0abbbbacf36a98c18100ee0da02f28a 178 Gene3D G3DSA:2.60.120.40 35 173 3.7E-20 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS16390 b0abbbbacf36a98c18100ee0da02f28a 178 SUPERFAMILY SSF49842 38 170 9.94E-20 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS16390 b0abbbbacf36a98c18100ee0da02f28a 178 Pfam PF00386 C1q domain 39 152 6.8E-6 T 29-03-2018 IPR001073 C1q domain CSW12_RS14505 efc3f6b4a2800b636fc96704748248d7 49 Pfam PF13128 Protein of unknown function (DUF3954) 3 47 1.5E-19 T 29-03-2018 IPR025017 Protein of unknown function DUF3954 CSW12_RS02740 13dc5afc2d293fb36e693531cd64717b 490 Pfam PF00474 Sodium:solute symporter family 34 427 1.3E-23 T 29-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS04325 87553d40d6358344654104f6fa5fa810 89 Gene3D G3DSA:3.30.1340.10 7 87 1.5E-4 T 29-03-2018 IPR000032 Phosphocarrier protein HPr-like CSW12_RS20765 2adaa0f9c7c997890fec41867998f559 66 Pfam PF14038 YqzE-like protein 2 55 1.4E-28 T 29-03-2018 IPR025622 YqzE-like protein CSW12_RS11055 f00cf7bc80f222f9d4be4de76e340e7c 57 Pfam PF06906 Protein of unknown function (DUF1272) 2 56 2.5E-26 T 29-03-2018 IPR010696 Protein of unknown function DUF1272 CSW12_RS25020 9c682df550d4879adbeb30ed09b50ae6 144 Pfam PF13058 Protein of unknown function (DUF3920) 17 142 1.2E-68 T 29-03-2018 IPR025033 Protein of unknown function DUF3920 CSW12_RS24925 05a2c58c048a456b072445c52ed67d38 46 Pfam PF13153 Protein of unknown function (DUF3985) 1 44 6.6E-27 T 29-03-2018 IPR025053 Protein of unknown function DUF3985 CSW12_RS01245 9b15c3253c05d27e695f2e80cf0ac9c8 362 Pfam PF06081 Aromatic acid exporter family member 1 1 142 4.2E-45 T 29-03-2018 IPR010343 Aromatic acid exporter family member 1 CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 SMART SM00418 21 100 1.5E-22 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 Pfam PF12840 Helix-turn-helix domain 20 79 7.4E-12 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 SUPERFAMILY SSF46785 11 98 5.15E-23 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.5E-8 T 29-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CSW12_RS30350 665d65972d7a578e5f9e74f18af5da07 100 Gene3D G3DSA:1.10.10.10 6 99 1.1E-18 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16345 1628adefd296b3508b86641464456cc7 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 8.5E-24 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CSW12_RS16680 39a8ef409a0b05464cac2b941ed5a6e6 608 Pfam PF09823 Domain of unknown function (DUF2357) 130 311 4.3E-7 T 29-03-2018 IPR018633 Domain of unknown function DUF2357 CSW12_RS16680 39a8ef409a0b05464cac2b941ed5a6e6 608 Pfam PF04411 PD-(D/E)XK nuclease superfamily 388 505 3.0E-6 T 29-03-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 CSW12_RS23035 4aabbe70450a23d712df343468f2b8cb 124 Pfam PF14119 Domain of unknown function (DUF4288) 6 101 6.5E-30 T 29-03-2018 IPR025630 Protein of unknown function DUF4288 CSW12_RS19965 7cf409e4e900ca54a43aa92882f1bae4 262 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 24 256 8.1E-102 T 29-03-2018 IPR014231 Sporulation protein YpjB CSW12_RS19965 7cf409e4e900ca54a43aa92882f1bae4 262 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 25 254 1.1E-86 T 29-03-2018 IPR014231 Sporulation protein YpjB CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 SUPERFAMILY SSF56959 36 328 1.31E-91 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 Pfam PF07968 Leukocidin/Hemolysin toxin family 62 313 5.3E-79 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 TIGRFAM TIGR01002 hlyII: beta-channel forming cytolysin 3 318 1.3E-124 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 Gene3D G3DSA:2.70.240.10 35 318 7.5E-89 T 29-03-2018 IPR016183 Leukocidin/porin GO:0005576|GO:0051715 CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 66 85 1.5E-5 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 126 147 1.5E-5 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS10170 c9e45529d37dfc5d62a75ca776d0c809 412 PRINTS PR01468 Staphylococcal bi-component toxin signature 249 266 1.5E-5 T 29-03-2018 IPR003963 Bi-component toxin, staphylococci GO:0005576|GO:0009405 CSW12_RS23640 0000bb4e143349a1519160cc3d8306c1 268 Gene3D G3DSA:1.10.3720.10 6 255 4.1E-28 T 29-03-2018 CSW12_RS23640 0000bb4e143349a1519160cc3d8306c1 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 259 1.8E-25 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS23640 0000bb4e143349a1519160cc3d8306c1 268 SUPERFAMILY SSF161098 67 249 5.49E-30 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS23750 d861e630991c7d0a77304924b660fdd1 168 Pfam PF13785 Domain of unknown function (DUF4178) 28 158 9.1E-26 T 29-03-2018 IPR025235 Domain of unknown function DUF4178 CSW12_RS06670 a7bdf1e1b6771c994f081eed7e53bdb3 149 Pfam PF13027 Protein of unknown function (DUF3888) 49 133 1.6E-20 T 29-03-2018 IPR024984 Protein of unknown function DUF3888 CSW12_RS01750 b85ff3e20dbf0608335733e8c1b4e338 128 SUPERFAMILY SSF54593 1 127 6.18E-31 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS01750 b85ff3e20dbf0608335733e8c1b4e338 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 125 2.9E-18 T 29-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CSW12_RS01750 b85ff3e20dbf0608335733e8c1b4e338 128 Gene3D G3DSA:3.10.180.10 1 128 7.5E-28 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS00655 de4a2230d5593bb36032b743519a8cff 260 Pfam PF10127 Predicted nucleotidyltransferase 1 249 8.6E-97 T 29-03-2018 IPR018775 Nucleotidyltransferase, predicted CSW12_RS00655 de4a2230d5593bb36032b743519a8cff 260 Gene3D G3DSA:3.30.460.10 2 118 1.9E-5 T 29-03-2018 CSW12_RS03975 4ad6ab5d21c609ca0601fe547c9899a0 255 Pfam PF01925 Sulfite exporter TauE/SafE 13 247 2.5E-42 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS23080 a90085d19586616f47d0e2ce57d90a58 371 Gene3D G3DSA:3.40.1830.10 2 165 5.3E-45 T 29-03-2018 IPR035097 Peptidase M29, N-terminal CSW12_RS23080 a90085d19586616f47d0e2ce57d90a58 371 SUPERFAMILY SSF144052 1 360 3.53E-112 T 29-03-2018 CSW12_RS23080 a90085d19586616f47d0e2ce57d90a58 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 338 3.6E-60 T 29-03-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 CSW12_RS18180 aa355b2eb0c1b36b9d27bb6c9b4bf3bd 182 Pfam PF16157 Domain of unknown function (DUF4865) 1 181 4.9E-67 T 29-03-2018 IPR032349 Protein of unknown function DUF4865 CSW12_RS08900 81c04c342a3ba675e6d0197d487c04f1 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 1.7E-38 T 29-03-2018 IPR007347 Sporulation stage V, protein S CSW12_RS08900 81c04c342a3ba675e6d0197d487c04f1 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 1.0E-40 T 29-03-2018 IPR007347 Sporulation stage V, protein S CSW12_RS23200 ef74955227234635b79ee571826701e3 181 SUPERFAMILY SSF55144 4 180 1.74E-39 T 29-03-2018 IPR009097 Cyclic phosphodiesterase CSW12_RS23200 ef74955227234635b79ee571826701e3 181 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 179 22.408 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CSW12_RS23200 ef74955227234635b79ee571826701e3 181 Pfam PF02834 LigT like Phosphoesterase 99 171 7.9E-10 T 29-03-2018 IPR014051 Phosphoesterase, HXTX CSW12_RS23200 ef74955227234635b79ee571826701e3 181 Pfam PF02834 LigT like Phosphoesterase 10 92 8.3E-14 T 29-03-2018 IPR014051 Phosphoesterase, HXTX CSW12_RS23200 ef74955227234635b79ee571826701e3 181 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 4 179 4.8E-56 T 29-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CSW12_RS23200 ef74955227234635b79ee571826701e3 181 Gene3D G3DSA:3.90.1140.10 1 181 1.1E-34 T 29-03-2018 CSW12_RS07350 a161a6a1046a24003f84a2c8a39ab84b 189 Pfam PF14097 Stage V sporulation protein AE1 4 183 1.5E-81 T 29-03-2018 IPR025914 Stage V sporulation protein AE CSW12_RS18160 85ebbc8dadc8afa10c99b22af536e950 351 SUPERFAMILY SSF51679 22 347 1.15E-66 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CSW12_RS18160 85ebbc8dadc8afa10c99b22af536e950 351 Pfam PF00296 Luciferase-like monooxygenase 27 308 6.6E-44 T 29-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CSW12_RS18160 85ebbc8dadc8afa10c99b22af536e950 351 Gene3D G3DSA:3.20.20.30 1 351 1.4E-61 T 29-03-2018 CSW12_RS10985 2548ca6972e0a033a9501a7ba048a7c1 123 Pfam PF06993 Protein of unknown function (DUF1304) 11 120 2.4E-39 T 29-03-2018 IPR009732 Protein of unknown function DUF1304 CSW12_RS18135 1bd4c97bdcaa59916e6b53a5644e4ea8 400 Gene3D G3DSA:3.40.50.1110 64 397 1.9E-6 T 29-03-2018 CSW12_RS29825 f33cdbf03fa78fa8fff3fa39362b16a3 249 Pfam PF02517 CAAX protease self-immunity 127 234 1.2E-11 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS14710 b439057b437b2d380ccb3987decd38a3 643 PIRSF PIRSF018968 1 641 2.3E-129 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS14710 b439057b437b2d380ccb3987decd38a3 643 Pfam PF02687 FtsX-like permease family 90 181 2.4E-8 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS12135 b3b9e1508913e886f3d26ae1365c7153 197 Pfam PF03992 Antibiotic biosynthesis monooxygenase 22 90 7.9E-7 T 29-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CSW12_RS12135 b3b9e1508913e886f3d26ae1365c7153 197 SUPERFAMILY SSF54909 15 113 7.75E-18 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS12135 b3b9e1508913e886f3d26ae1365c7153 197 Gene3D G3DSA:3.30.70.100 16 125 1.2E-15 T 29-03-2018 CSW12_RS28690 29d9f306dea1dac1c1e4688915ea22d6 337 SUPERFAMILY SSF89392 28 205 1.96E-17 T 29-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CSW12_RS28690 29d9f306dea1dac1c1e4688915ea22d6 337 Gene3D G3DSA:2.50.20.10 25 218 2.8E-23 T 29-03-2018 CSW12_RS29210 bb538df48de6c56523d312587730eb0f 323 Pfam PF12642 Conjugative transposon protein TcpC 88 318 3.4E-41 T 29-03-2018 IPR024735 Conjugative transposon protein TcpC CSW12_RS09010 cb2255e3b39a66c8bb26b657deae30a4 223 Pfam PF04172 LrgB-like family 7 217 6.2E-62 T 29-03-2018 IPR007300 CidB/LrgB family CSW12_RS24465 dffdd4d8e638e1d2bf266a84c7c1ce76 256 Gene3D G3DSA:3.30.1450.10 181 255 2.1E-10 T 29-03-2018 CSW12_RS24465 dffdd4d8e638e1d2bf266a84c7c1ce76 256 Gene3D G3DSA:3.30.1450.10 67 143 9.6E-4 T 29-03-2018 CSW12_RS05035 c9fe9eddac9444d943c6efbd2bba3daf 184 ProDom PD106196 YISN IG BH1722 3 177 2.0E-99 T 29-03-2018 IPR024488 Protein of unknown function DUF2777 CSW12_RS05035 c9fe9eddac9444d943c6efbd2bba3daf 184 Pfam PF10949 Protein of unknown function (DUF2777) 3 182 9.2E-71 T 29-03-2018 IPR024488 Protein of unknown function DUF2777 CSW12_RS17555 dde30d15f7dbfb7d41ded8206cae4eca 246 Gene3D G3DSA:3.30.1380.10 75 240 4.5E-38 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS17555 dde30d15f7dbfb7d41ded8206cae4eca 246 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 99 227 3.2E-45 T 29-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CSW12_RS17555 dde30d15f7dbfb7d41ded8206cae4eca 246 SUPERFAMILY SSF55166 91 236 1.07E-36 T 29-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CSW12_RS03415 8ac933c826a75f3e2c72532d32d47d51 141 Pfam PF13157 Protein of unknown function (DUF3992) 55 134 1.1E-6 T 29-03-2018 IPR025055 Protein of unknown function DUF3992 CSW12_RS19190 8a4895eaff383b7ba33153b898696c28 241 Pfam PF03591 AzlC protein 25 165 1.3E-40 T 29-03-2018 IPR011606 Branched-chain amino acid transport, permease CSW12_RS13275 b8c3704857b4e6f5aa66e1ea7193c7b7 206 Pfam PF13171 Protein of unknown function (DUF4004) 8 198 1.7E-82 T 29-03-2018 IPR025063 Protein of unknown function DUF4004 CSW12_RS13275 b8c3704857b4e6f5aa66e1ea7193c7b7 206 Gene3D G3DSA:1.10.1660.10 3 79 2.9E-7 T 29-03-2018 CSW12_RS13075 8ad1573da5c65195719c4f1cb5b2d014 282 Gene3D G3DSA:1.10.3720.10 28 275 2.6E-21 T 29-03-2018 CSW12_RS13075 8ad1573da5c65195719c4f1cb5b2d014 282 SUPERFAMILY SSF161098 76 255 5.63E-29 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS13075 8ad1573da5c65195719c4f1cb5b2d014 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 267 1.1E-24 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS09775 76a984d745ca0a9c3f3b630cbe99ba20 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 140 6.2E-9 T 29-03-2018 IPR028973 PhnB-like CSW12_RS09775 76a984d745ca0a9c3f3b630cbe99ba20 147 Gene3D G3DSA:3.10.180.10 1 147 1.6E-14 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS09775 76a984d745ca0a9c3f3b630cbe99ba20 147 SUPERFAMILY SSF54593 5 144 3.15E-21 T 29-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CSW12_RS24610 a14f33656950c5f2cebc61be55426b40 146 Gene3D G3DSA:1.20.120.580 1 144 7.6E-35 T 29-03-2018 IPR008201 Protein of unknown function DUF86 CSW12_RS24610 a14f33656950c5f2cebc61be55426b40 146 Pfam PF01934 Protein of unknown function DUF86 12 126 1.3E-21 T 29-03-2018 IPR008201 Protein of unknown function DUF86 CSW12_RS12555 aeb1bf5b661146a9d8f5a0dcf626abd0 369 Pfam PF01882 Protein of unknown function DUF58 211 289 1.0E-11 T 29-03-2018 IPR002881 Domain of unknown function DUF58 CSW12_RS21595 bb8943f14524fa603f89e3e23e88e76f 42 Pfam PF13056 Protein of unknown function (DUF3918) 3 42 1.1E-19 T 29-03-2018 IPR025029 Protein of unknown function DUF3918 CSW12_RS15755 002dde706cc276350a203d0ee3d84bde 101 Gene3D G3DSA:3.40.50.2300 1 101 4.0E-30 T 29-03-2018 CSW12_RS15755 002dde706cc276350a203d0ee3d84bde 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 1.4E-16 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS15755 002dde706cc276350a203d0ee3d84bde 101 SUPERFAMILY SSF52794 1 100 3.14E-27 T 29-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CSW12_RS07385 d91235549e8ed06e4c6212e7b7b79bed 31 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 7 30 1.4E-11 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS07385 d91235549e8ed06e4c6212e7b7b79bed 31 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 6 28 3.2E-12 T 29-03-2018 IPR010070 Conserved hypothetical protein CHP01732, Tiny-TM CSW12_RS10540 ec8b6cf76934950bba797a81c43c1358 253 Pfam PF02517 CAAX protease self-immunity 116 212 1.0E-15 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS19780 fd3b9d8093a1e590b9bb68fcc251cc8e 60 Pfam PF13060 Protein of unknown function (DUF3921) 1 58 2.3E-42 T 29-03-2018 IPR025036 Protein of unknown function DUF3921 CSW12_RS00325 8351e85c88291dbbe7dc3ec2932f2cbe 125 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 17 86 7.1E-8 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CSW12_RS00325 8351e85c88291dbbe7dc3ec2932f2cbe 125 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 6 120 6.5E-9 T 29-03-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component CSW12_RS11925 fff50231c8d8cedc886905baf6952b4b 233 Pfam PF07423 Protein of unknown function (DUF1510) 5 231 7.6E-64 T 29-03-2018 IPR009988 Protein of unknown function DUF1510 CSW12_RS02565 e5556c58daac2866de5f604d1a6e1a65 275 Gene3D G3DSA:2.160.20.50 189 251 4.9E-11 T 29-03-2018 CSW12_RS02565 e5556c58daac2866de5f604d1a6e1a65 275 Gene3D G3DSA:2.160.20.50 137 188 7.5E-7 T 29-03-2018 CSW12_RS02565 e5556c58daac2866de5f604d1a6e1a65 275 Pfam PF01391 Collagen triple helix repeat (20 copies) 148 200 6.6E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS02565 e5556c58daac2866de5f604d1a6e1a65 275 Pfam PF01391 Collagen triple helix repeat (20 copies) 188 240 7.4E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS02280 e5556c58daac2866de5f604d1a6e1a65 275 Gene3D G3DSA:2.160.20.50 189 251 4.9E-11 T 29-03-2018 CSW12_RS02280 e5556c58daac2866de5f604d1a6e1a65 275 Gene3D G3DSA:2.160.20.50 137 188 7.5E-7 T 29-03-2018 CSW12_RS02280 e5556c58daac2866de5f604d1a6e1a65 275 Pfam PF01391 Collagen triple helix repeat (20 copies) 148 200 6.6E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS02280 e5556c58daac2866de5f604d1a6e1a65 275 Pfam PF01391 Collagen triple helix repeat (20 copies) 188 240 7.4E-9 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS05235 91d5e4e5c14becf1bf693ad856d89a4d 494 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 107 461 3.8E-22 T 29-03-2018 CSW12_RS05235 91d5e4e5c14becf1bf693ad856d89a4d 494 Pfam PF14296 O-antigen polysaccharide polymerase Wzy 9 483 3.7E-86 T 29-03-2018 IPR029468 O-antigen polysaccharide polymerase Wzy CSW12_RS10380 7693f7ff2f67579c2171cef41696fa48 322 Pfam PF01758 Sodium Bile acid symporter family 41 220 4.2E-41 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CSW12_RS28640 523e1ddc93ae2985d40764df82bda676 318 Gene3D G3DSA:3.90.850.10 42 308 1.1E-68 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CSW12_RS28640 523e1ddc93ae2985d40764df82bda676 318 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 298 3.4E-64 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CSW12_RS28640 523e1ddc93ae2985d40764df82bda676 318 SUPERFAMILY SSF56529 77 299 7.59E-70 T 29-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CSW12_RS19975 4bca198c784a3641d9def1b7cf4a0b2b 190 Pfam PF07187 Protein of unknown function (DUF1405) 18 174 1.9E-57 T 29-03-2018 IPR009845 Protein of unknown function DUF1405 CSW12_RS22265 73858c6fa9ef98c779242ac559290bc6 231 Pfam PF12730 ABC-2 family transporter protein 6 183 9.0E-8 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CSW12_RS14700 b7b64e05ad32e6c5b71dc112f14c57b9 113 Pfam PF13053 Protein of unknown function (DUF3914) 1 89 7.6E-60 T 29-03-2018 IPR025025 Protein of unknown function DUF3914 CSW12_RS21145 e2ec490bc5cdb269e0f0ae653b2962bb 97 Pfam PF07873 YabP family 26 89 8.1E-17 T 29-03-2018 IPR022476 Sporulation protein YabP/YqfC CSW12_RS21145 e2ec490bc5cdb269e0f0ae653b2962bb 97 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 7 90 1.1E-36 T 29-03-2018 IPR022477 Sporulation protein YqfC CSW12_RS00515 cd943e7f49fb7936b6846ef75a73c338 235 Pfam PF01863 Protein of unknown function DUF45 20 227 6.2E-61 T 29-03-2018 IPR002725 Protein of unknown function DUF45 CSW12_RS08110 fd7d1d182e5eb120e8f433f8640e61c9 409 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 10 390 9.7E-125 T 29-03-2018 IPR014226 Sporulation integral membrane protein YlbJ CSW12_RS20415 a7010e24b1cbd9ea472d5dcd6f7cb2d9 77 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 2.0E-29 T 29-03-2018 IPR020138 Uncharacterised protein family YqzF CSW12_RS20415 a7010e24b1cbd9ea472d5dcd6f7cb2d9 77 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 2.2E-29 T 29-03-2018 IPR020138 Uncharacterised protein family YqzF CSW12_RS19455 66f7debd86b3362c19ac051910c03ff7 72 Pfam PF09388 Spo0E like sporulation regulatory protein 24 65 1.6E-12 T 29-03-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 CSW12_RS19455 66f7debd86b3362c19ac051910c03ff7 72 SUPERFAMILY SSF140500 19 70 1.05E-14 T 29-03-2018 CSW12_RS00895 b555b35012f6e3ddf1abf812c918e7bc 198 Pfam PF02342 TerD domain 1 197 7.7E-68 T 29-03-2018 IPR003325 TerD domain GO:0006950 CSW12_RS00895 b555b35012f6e3ddf1abf812c918e7bc 198 Gene3D G3DSA:2.60.60.30 18 195 6.4E-53 T 29-03-2018 CSW12_RS06755 e867abcbb7deee3b6d30c0943d5a8f92 438 Pfam PF03553 Na+/H+ antiporter family 71 211 7.1E-13 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CSW12_RS06755 e867abcbb7deee3b6d30c0943d5a8f92 438 Pfam PF03553 Na+/H+ antiporter family 240 421 3.2E-13 T 29-03-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CSW12_RS26565 a22a824edf446efd4bb76e84de8bbc2a 244 PIRSF PIRSF006648 1 243 5.9E-22 T 29-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CSW12_RS26565 a22a824edf446efd4bb76e84de8bbc2a 244 Pfam PF12698 ABC-2 family transporter protein 51 236 5.4E-17 T 29-03-2018 CSW12_RS26540 f957c4ea630d86c270b89bebf2a65617 48 Pfam PF05968 Bacillus PapR protein 1 48 3.2E-34 T 29-03-2018 IPR009239 Bacillus PapR CSW12_RS06010 594d6afa5f5d7f43440816b73f135278 201 Pfam PF07853 Protein of unknown function (DUF1648) 10 56 3.8E-16 T 29-03-2018 IPR012867 Domain of unknown function DUF1648 CSW12_RS23760 dae9ff4c3fe7232a7ec8cd18a608aa86 221 Pfam PF04012 PspA/IM30 family 2 218 3.9E-48 T 29-03-2018 IPR007157 PspA/IM30 CSW12_RS27450 32561e7d15cf01417ccc450297bd0e52 73 Pfam PF10704 Protein of unknown function (DUF2508) 1 69 5.8E-27 T 29-03-2018 IPR019644 Protein of unknown function DUF2508 CSW12_RS01490 045a9be253bc35561a5bcdff1a3c1133 182 Gene3D G3DSA:2.40.50.140 95 175 4.1E-15 T 29-03-2018 CSW12_RS10425 15d3db2b95fee50e4a4bba30d0143114 169 Pfam PF13079 Protein of unknown function (DUF3916) 17 167 4.1E-66 T 29-03-2018 IPR025075 Protein of unknown function DUF3916 CSW12_RS15840 8aac7326432ea4ddc27a7701cbba8825 262 Pfam PF13704 Glycosyl transferase family 2 13 99 2.1E-9 T 29-03-2018 CSW12_RS22505 e716e15448eb6d471816d93c47953999 65 Pfam PF13783 Domain of unknown function (DUF4177) 2 62 4.5E-17 T 29-03-2018 IPR025234 Protein of unknown function DUF4177 CSW12_RS30640 3adcc021b1a256ba6038a20e58beece5 178 SUPERFAMILY SSF49695 84 154 5.36E-7 T 29-03-2018 IPR011024 Gamma-crystallin-related CSW12_RS30640 3adcc021b1a256ba6038a20e58beece5 178 Gene3D G3DSA:2.60.20.10 67 178 5.5E-13 T 29-03-2018 CSW12_RS16140 77813f5d6fcfeee82bcf358a38ea60fd 255 Pfam PF13030 Protein of unknown function (DUF3891) 1 229 1.0E-64 T 29-03-2018 IPR024992 Protein of unknown function DUF3891 CSW12_RS26350 00462bfb21b4e91f591870d088fd8ea9 37 Pfam PF13216 Protein of unknown function (DUF4024) 1 35 1.5E-28 T 29-03-2018 IPR025099 Protein of unknown function DUF4024 CSW12_RS26245 d7dafe7f1587881c2d36c5780a9bae11 174 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 1.2E-34 T 29-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CSW12_RS26240 32ea691d24513e65e5bbe320b76b12db 104 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 104 20.212 T 29-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CSW12_RS26240 32ea691d24513e65e5bbe320b76b12db 104 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 99 2.3E-24 T 29-03-2018 CSW12_RS18725 66cb30b2f41e87d74c9cf418673e1845 179 Pfam PF03551 Transcriptional regulator PadR-like family 7 79 2.5E-14 T 29-03-2018 IPR005149 Transcription regulator PadR, N-terminal CSW12_RS18725 66cb30b2f41e87d74c9cf418673e1845 179 SUPERFAMILY SSF46785 5 170 1.01E-34 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS18725 66cb30b2f41e87d74c9cf418673e1845 179 Gene3D G3DSA:1.10.10.10 4 92 1.7E-21 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS22710 71d657f10635c80492598e09122cc74c 275 Pfam PF10978 Protein of unknown function (DUF2785) 76 249 6.8E-50 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 CSW12_RS03575 ff289443d4bb3d8952feccbb209c46d2 361 Pfam PF12294 Protein of unknown function (DUF3626) 55 355 1.2E-145 T 29-03-2018 IPR022074 Protein of unknown function DUF3626 CSW12_RS19835 f64832c8b2f5d5a99337c3243e932187 332 Pfam PF10720 Protein of unknown function (DUF2515) 18 319 7.3E-127 T 29-03-2018 IPR019658 Protein of unknown function DUF2515 CSW12_RS10125 8bc138b277b4473cf7225bdaadda2f25 146 Gene3D G3DSA:2.60.120.380 22 146 2.8E-4 T 29-03-2018 CSW12_RS05345 f76cfe62985dc2211a4aaa983e2a21c8 43 Pfam PF13081 Domain of unknown function (DUF3941) 18 41 1.1E-14 T 29-03-2018 IPR025077 Protein of unknown function DUF3941 CSW12_RS13105 259ca57b46e704b1d0e6914ae56a5598 46 Pfam PF09501 Probable sporulation protein (Bac_small_yrzI) 1 45 2.9E-19 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS13105 259ca57b46e704b1d0e6914ae56a5598 46 TIGRFAM TIGR02413 Bac_small_yrzI: Bacillus tandem small hypothetical protein 1 46 2.7E-22 T 29-03-2018 IPR012655 Uncharacterised protein YrzI CSW12_RS18305 d3191e25821a7c4a7fa5d1bda7c92090 319 Pfam PF01758 Sodium Bile acid symporter family 38 221 1.1E-27 T 29-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CSW12_RS28160 f06c0937fa0d0ebba5476691ef55f7fa 142 Pfam PF10730 Protein of unknown function (DUF2521) 1 142 6.8E-55 T 29-03-2018 IPR019667 Uncharacterised protein family YbaK CSW12_RS07980 1a54c6b681fe3248309744b660323389 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 5.0E-31 T 29-03-2018 IPR019241 Protein of unknown function DUF2197 CSW12_RS01230 e6ddf860513c2aa00ef988a69f4e8323 86 Pfam PF14182 YgaB-like protein 3 78 1.8E-29 T 29-03-2018 IPR025572 YgaB-like protein CSW12_RS19995 37608d4701746f99978a42760111b6ad 153 Pfam PF10673 Protein of unknown function (DUF2487) 9 149 6.6E-53 T 29-03-2018 IPR019615 Protein of unknown function DUF2487 CSW12_RS10850 2ea6cc9ef47eaafd90aaf1f282175e7e 141 Pfam PF07291 Methylamine utilisation protein MauE 9 124 5.4E-5 T 29-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 CSW12_RS05260 7746aadddeb8cc6d4ceb96d3fa7f1de2 277 Gene3D G3DSA:1.10.10.10 16 104 6.6E-5 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS23805 70af0ec87623497aa822ef3799d573b4 157 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 122 154 5.6E-4 T 29-03-2018 CSW12_RS07220 144fa12b305a3eb8047eaff141d558cb 90 Pfam PF14004 Protein of unknown function (DUF4227) 20 90 8.7E-29 T 29-03-2018 IPR025321 Protein of unknown function DUF4227 CSW12_RS03240 a6a76a069b3167bf2d9929d08e6663f4 98 Gene3D G3DSA:3.40.250.10 1 98 6.7E-25 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03240 a6a76a069b3167bf2d9929d08e6663f4 98 Pfam PF00581 Rhodanese-like domain 5 94 3.4E-14 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03240 a6a76a069b3167bf2d9929d08e6663f4 98 SUPERFAMILY SSF52821 2 94 2.49E-28 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS03240 a6a76a069b3167bf2d9929d08e6663f4 98 SMART SM00450 5 97 1.4E-17 T 29-03-2018 IPR001763 Rhodanese-like domain CSW12_RS16410 ce2637f8f955815bdcf30f7189358b1a 39 Pfam PF13239 2TM domain 10 37 2.3E-8 T 29-03-2018 IPR025698 2TM domain CSW12_RS08215 07822c76ee47b5824f22dd538457c117 256 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 254 31.885 T 29-03-2018 IPR026580 Cell division protein DivIB CSW12_RS08215 07822c76ee47b5824f22dd538457c117 256 Pfam PF03799 Cell division protein FtsQ 126 240 7.3E-8 T 29-03-2018 IPR005548 Cell division protein FtsQ/DivIB CSW12_RS08215 07822c76ee47b5824f22dd538457c117 256 Pfam PF08478 POTRA domain, FtsQ-type 53 121 5.9E-20 T 29-03-2018 IPR013685 POTRA domain, FtsQ-type CSW12_RS00365 d5db32f8a070abcfa6eafca336fed3cf 397 Pfam PF02371 Transposase IS116/IS110/IS902 family 270 354 1.0E-27 T 29-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CSW12_RS00365 d5db32f8a070abcfa6eafca336fed3cf 397 Pfam PF01548 Transposase 4 162 8.7E-46 T 29-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CSW12_RS00140 30c2ec06a37fcc7c7c69be0daebaa5ce 185 Pfam PF00857 Isochorismatase family 3 152 5.1E-35 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS00140 30c2ec06a37fcc7c7c69be0daebaa5ce 185 Gene3D G3DSA:3.40.50.850 1 182 4.8E-46 T 29-03-2018 CSW12_RS00140 30c2ec06a37fcc7c7c69be0daebaa5ce 185 SUPERFAMILY SSF52499 2 180 7.33E-53 T 29-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CSW12_RS01765 734387843c3b3065604c5464b9756bbb 539 Pfam PF02652 L-lactate permease 16 530 1.3E-175 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CSW12_RS01765 734387843c3b3065604c5464b9756bbb 539 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 535 1.3E-182 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CSW12_RS25110 f9bbbe7b3123af19389fcb34460279f0 929 Pfam PF03272 Putative mucin or carbohydrate-binding module 608 723 1.8E-19 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS25110 f9bbbe7b3123af19389fcb34460279f0 929 Pfam PF03272 Putative mucin or carbohydrate-binding module 3 113 3.0E-17 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS25110 f9bbbe7b3123af19389fcb34460279f0 929 Pfam PF03272 Putative mucin or carbohydrate-binding module 806 925 9.3E-29 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS25110 f9bbbe7b3123af19389fcb34460279f0 929 Pfam PF03272 Putative mucin or carbohydrate-binding module 410 518 1.6E-15 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS25110 f9bbbe7b3123af19389fcb34460279f0 929 Pfam PF03272 Putative mucin or carbohydrate-binding module 196 315 4.1E-24 T 29-03-2018 IPR004954 Putative mucin or carbohydrate-binding domain GO:0016032 CSW12_RS25860 04b45e996e372ed284e26e3f8cffe9be 121 Pfam PF01610 Transposase 14 111 4.4E-10 T 29-03-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CSW12_RS08260 1400d5aef2089ffae8a83dde1e71883f 156 Pfam PF04472 Cell division protein SepF 66 137 1.0E-29 T 29-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CSW12_RS08260 1400d5aef2089ffae8a83dde1e71883f 156 Hamap MF_01197 Cell division protein SepF [sepF]. 1 145 18.524 T 29-03-2018 IPR023052 Cell division protein SepF GO:0090529 CSW12_RS21030 33dacced37c6b728c2497c41b1355137 84 ProDom PD060869 YQFT IG BH1387 1 68 3.0E-31 T 29-03-2018 IPR020277 Protein of unknown function DUF2624 CSW12_RS21030 33dacced37c6b728c2497c41b1355137 84 Pfam PF11116 Protein of unknown function (DUF2624) 1 82 5.0E-32 T 29-03-2018 IPR020277 Protein of unknown function DUF2624 CSW12_RS24575 cd33626a4eb17917da576c4b7dfe367f 367 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 348 1.2E-123 T 29-03-2018 CSW12_RS24575 cd33626a4eb17917da576c4b7dfe367f 367 Gene3D G3DSA:3.20.20.360 24 320 8.8E-31 T 29-03-2018 CSW12_RS24575 cd33626a4eb17917da576c4b7dfe367f 367 PIRSF PIRSF015582 14 358 4.8E-83 T 29-03-2018 IPR011206 Citrate lyase beta subunit-like CSW12_RS24575 cd33626a4eb17917da576c4b7dfe367f 367 SUPERFAMILY SSF51621 34 292 2.04E-20 T 29-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CSW12_RS19745 e33158ba6340856d6cf277aa1d85466f 387 Pfam PF04235 Protein of unknown function (DUF418) 217 376 2.6E-38 T 29-03-2018 IPR007349 Domain of unknown function DUF418 CSW12_RS20665 6d3aaa6ae64c9c2a04d9d6bc45c51a63 104 Pfam PF00893 Small Multidrug Resistance protein 1 92 3.4E-27 T 29-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CSW12_RS20665 6d3aaa6ae64c9c2a04d9d6bc45c51a63 104 SUPERFAMILY SSF103481 5 102 1.44E-18 T 29-03-2018 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 Pfam PF01235 Sodium:alanine symporter family 49 459 1.4E-152 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 447 3.1E-142 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 PRINTS PR00175 Sodium/alanine symporter signature 204 223 7.1E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 PRINTS PR00175 Sodium/alanine symporter signature 353 375 7.1E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 PRINTS PR00175 Sodium/alanine symporter signature 295 313 7.1E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 PRINTS PR00175 Sodium/alanine symporter signature 176 194 7.1E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 PRINTS PR00175 Sodium/alanine symporter signature 416 436 7.1E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS13530 6fee81724bc34d4789e8e6a5b9cdb77a 496 PRINTS PR00175 Sodium/alanine symporter signature 86 108 7.1E-58 T 29-03-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 CSW12_RS05430 0175612e1b91a42b30cf761a570a5867 126 Pfam PF13038 Domain of unknown function (DUF3899) 35 122 2.8E-22 T 29-03-2018 IPR025007 Domain of unknown function DUF3899 CSW12_RS08045 80ea5a3ec277b64599b3aa90cced1260 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 5 109 4.8E-45 T 29-03-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CSW12_RS08045 80ea5a3ec277b64599b3aa90cced1260 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 28 101 8.9E-14 T 29-03-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CSW12_RS23575 906af5b4136fa102ed5ea8193eef38ce 241 Pfam PF13731 WxL domain surface cell wall-binding 31 240 4.8E-62 T 29-03-2018 IPR027994 WxL domain CSW12_RS06415 8330891e5084eaa0da1f70cecd06d89f 63 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 21 63 8.8E-20 T 29-03-2018 IPR021008 Protein of unknown function DUF3687 CSW12_RS15415 9b0cc5b374fedf5251246b90f0f3fdd2 406 SUPERFAMILY SSF58100 298 400 5.75E-84 T 29-03-2018 CSW12_RS15415 9b0cc5b374fedf5251246b90f0f3fdd2 406 SUPERFAMILY SSF58100 37 264 5.75E-84 T 29-03-2018 CSW12_RS15415 9b0cc5b374fedf5251246b90f0f3fdd2 406 Gene3D G3DSA:1.20.1170.10 42 406 1.3E-34 T 29-03-2018 CSW12_RS15415 9b0cc5b374fedf5251246b90f0f3fdd2 406 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 45 230 4.6E-66 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS23335 bfe77230d54485c67eda96619b135e7c 74 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 4.7E-17 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CSW12_RS03065 367ccb0fb2e35b83443fd26cc4d5bee4 433 Pfam PF00860 Permease family 14 394 1.8E-61 T 29-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CSW12_RS03065 367ccb0fb2e35b83443fd26cc4d5bee4 433 PIRSF PIRSF005353 1 433 6.9E-159 T 29-03-2018 IPR026033 Purine permease PbuG-like CSW12_RS02765 a74d032857a53963ad427291a2072e08 466 Pfam PF07670 Nucleoside recognition 309 434 6.3E-18 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS02765 a74d032857a53963ad427291a2072e08 466 Pfam PF07670 Nucleoside recognition 139 228 4.0E-9 T 29-03-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CSW12_RS02765 a74d032857a53963ad427291a2072e08 466 Pfam PF07664 Ferrous iron transport protein B C terminus 251 300 2.9E-14 T 29-03-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CSW12_RS03015 7a216716b727448c502f74bfced54278 34 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 7 30 6.1E-5 T 29-03-2018 IPR023833 Signal peptide, camelysin CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 370 427 9.0E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 86 138 1.4E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 656 714 2.0E-6 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 274 331 1.2E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 563 621 3.5E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 713 770 4.7E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 617 675 2.5E-7 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Pfam PF01391 Collagen triple helix repeat (20 copies) 41 96 6.2E-8 T 29-03-2018 IPR008160 Collagen triple helix repeat CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 TIGRFAM TIGR03720 exospor_lead: exosporium leader peptide 19 38 3.5E-6 T 29-03-2018 IPR021201 Leader peptide, exosporium CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 479 551 1.3E-9 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 405 478 9.9E-11 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 764 822 2.4E-12 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 688 763 2.8E-13 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 140 256 6.3E-4 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 257 309 7.7E-13 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 552 600 2.7E-12 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 601 664 1.7E-13 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.160.20.50 20 98 1.8E-10 T 29-03-2018 CSW12_RS23325 ae1ed79dd99e6880fd034539af44a32e 954 Gene3D G3DSA:2.60.120.40 823 954 2.3E-23 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS12405 d79ec6519cab29962db46b35288b24c0 488 ProSitePatterns PS00218 Amino acid permeases signature. 54 85 - T 29-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CSW12_RS12405 d79ec6519cab29962db46b35288b24c0 488 PIRSF PIRSF006060 2 481 1.0E-84 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS12405 d79ec6519cab29962db46b35288b24c0 488 Pfam PF00324 Amino acid permease 29 478 5.6E-136 T 29-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CSW12_RS04420 184b085bd35bc788565cd727d88d6b3d 364 SUPERFAMILY SSF48452 124 265 5.69E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04420 184b085bd35bc788565cd727d88d6b3d 364 Gene3D G3DSA:1.25.40.10 2 143 1.2E-29 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS04420 184b085bd35bc788565cd727d88d6b3d 364 Gene3D G3DSA:1.25.40.10 170 364 7.0E-14 T 29-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CSW12_RS13230 b0557546223f243a2576d15096f6b292 62 Pfam PF13113 Protein of unknown function (DUF3970) 1 56 1.8E-21 T 29-03-2018 IPR025088 Protein of unknown function DUF3970 CSW12_RS15855 6ecbdee260be5c928fcd83ba18242998 167 Gene3D G3DSA:2.60.120.40 18 167 6.0E-19 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS28495 2a55c05ecaea61cbe4a85192e9d28368 31 Pfam PF13134 Protein of unknown function (DUF3948) 1 26 5.2E-12 T 29-03-2018 IPR025034 Protein of unknown function DUF3948 CSW12_RS03195 9a11201e4c0e9ed90e7f52aa224c3c04 194 Pfam PF11579 Protein of unknown function (DUF3238) 1 192 6.5E-110 T 29-03-2018 IPR021631 Protein of unknown function DUF3238 CSW12_RS17315 2ae689668fd07014a0a15d3c2e62e6e7 69 Pfam PF13063 Protein of unknown function (DUF3925) 1 65 1.6E-46 T 29-03-2018 IPR025168 Protein of unknown function DUF3925 CSW12_RS16955 a14a8bf81de501f6fd7b5a3ad2bc1f97 191 Pfam PF06042 Nucleotidyltransferase 25 186 3.0E-57 T 29-03-2018 IPR009267 Putative nucleotidyltransferase CSW12_RS12420 db735727916698ae750ff38fe7dbb7cd 300 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 3.1E-39 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS19305 8157fd410e09fbad4c2476dbdaf2ce50 111 Pfam PF13107 Protein of unknown function (DUF3964) 2 108 1.6E-57 T 29-03-2018 IPR025082 Protein of unknown function DUF3964 CSW12_RS04955 8deb8f870483040613fb26afed43c1dd 197 Pfam PF09335 SNARE associated Golgi protein 43 161 5.0E-25 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS04980 8dba5304739b3495006e2e3d78ab516b 71 Pfam PF10676 Spore germination protein gerPA/gerPF 1 69 2.2E-24 T 29-03-2018 IPR019618 Spore germination protein GerPA/GerPF CSW12_RS05600 f0211e56d2113a7237ea055644c4d47f 228 Pfam PF13712 Glycosyltransferase like family 10 220 7.6E-81 T 29-03-2018 CSW12_RS22795 a532e09d0382409c5cf3b965f9d00cca 220 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 199 2.1E-43 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS02640 4cd3cb4d0f71860dbf57c4f70fea3d29 373 Pfam PF07046 Cytoplasmic repetitive antigen (CRA) like repeat 90 126 1.6E-4 T 29-03-2018 IPR009761 Cytoplasmic repetitive antigen-like CSW12_RS02640 4cd3cb4d0f71860dbf57c4f70fea3d29 373 Pfam PF07046 Cytoplasmic repetitive antigen (CRA) like repeat 82 113 9.7E-5 T 29-03-2018 IPR009761 Cytoplasmic repetitive antigen-like CSW12_RS01740 f8f2510bce9898727e237754100870e0 338 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 101 248 2.8E-45 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS01740 f8f2510bce9898727e237754100870e0 338 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 101 249 1.7E-41 T 29-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CSW12_RS14180 3c9c46a1acc143f35f7a2aea8cc93dc2 259 Pfam PF02673 Bacitracin resistance protein BacA 6 249 4.2E-77 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS14180 3c9c46a1acc143f35f7a2aea8cc93dc2 259 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 254 17.436 T 29-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CSW12_RS05135 27490674f2b564e10d5f0ab2ccc5d2ca 93 Gene3D G3DSA:1.10.720.10 58 93 2.7E-4 T 29-03-2018 CSW12_RS19115 bc83e022addd536eaa82ba5061ea1764 277 Gene3D G3DSA:2.40.320.10 23 262 4.2E-22 T 29-03-2018 CSW12_RS19685 809b890a9429ddad26334bf731e6d24d 128 Pfam PF03994 Domain of Unknown Function (DUF350) 72 126 1.6E-15 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CSW12_RS19685 809b890a9429ddad26334bf731e6d24d 128 Pfam PF03994 Domain of Unknown Function (DUF350) 7 58 8.2E-11 T 29-03-2018 IPR007140 Protein of unknown function DUF350 CSW12_RS25840 85deaa07625e9e5fd68cd4b9f3d6aa29 451 PIRSF PIRSF006446 1 451 1.8E-106 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CSW12_RS25840 85deaa07625e9e5fd68cd4b9f3d6aa29 451 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 436 1.0E-116 T 29-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CSW12_RS24915 e0339b947939cc28addd3deeff3a1af4 128 Pfam PF13074 Protein of unknown function (DUF3938) 25 126 7.4E-71 T 29-03-2018 IPR025070 Protein of unknown function DUF3938 CSW12_RS30965 ad22359eac9ad1a6207b82def4968cb9 96 Pfam PF17332 Uncharacterized protein pXO2-11 4 93 1.6E-27 T 29-03-2018 CSW12_RS07635 6f20faaba0dff273d6987f6f8713cebf 151 Pfam PF06271 RDD family 9 144 1.6E-24 T 29-03-2018 IPR010432 RDD CSW12_RS05375 061bdb67a5d04b8abed5ba7626b83dc1 59 Pfam PF14168 YjzC-like protein 1 55 1.4E-27 T 29-03-2018 IPR025549 YjzC-like protein CSW12_RS07110 c9604e345e3e4d016035fcc1ed748b36 203 PIRSF PIRSF036710 1 203 2.9E-97 T 29-03-2018 IPR014617 Predicted membrane protein, Bacillus YphA type CSW12_RS17595 2f246a1b11ff92ed8ba2e2fff274aadd 448 Pfam PF05525 Branched-chain amino acid transport protein 12 436 1.2E-153 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS17595 2f246a1b11ff92ed8ba2e2fff274aadd 448 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 17 423 9.0E-144 T 29-03-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 CSW12_RS05245 89736c7a9984f95f06921b90f76f6da9 95 Pfam PF10960 BhlA holin family 5 89 1.3E-6 T 29-03-2018 IPR024405 Prophage protein BhlA/UviB CSW12_RS14590 f55a657364188a1337d53bb8ee3e7008 51 Pfam PF07561 Domain of Unknown Function (DUF1540) 5 47 1.9E-15 T 29-03-2018 IPR011437 Domain of unknown function DUF1540 CSW12_RS23725 399478cd58d5203c8c0edfff8473836a 344 Pfam PF02698 DUF218 domain 164 313 2.6E-31 T 29-03-2018 IPR003848 Domain of unknown function DUF218 CSW12_RS23725 399478cd58d5203c8c0edfff8473836a 344 Gene3D G3DSA:3.40.50.620 154 304 9.2E-32 T 29-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CSW12_RS10560 ca78047833315e37813b3444c88c3dea 254 Pfam PF05675 Protein of unknown function (DUF817) 6 240 3.9E-104 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CSW12_RS10560 ca78047833315e37813b3444c88c3dea 254 PIRSF PIRSF009141 1 254 1.3E-126 T 29-03-2018 IPR008535 Protein of unknown function DUF817 CSW12_RS05415 b42f0143ee2265e8f33f46b35706496a 262 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 63 254 5.2E-49 T 29-03-2018 IPR018728 Domain of unknown function DUF2268 CSW12_RS22515 9c8e85e0bc176a537f31e28632b188a8 469 Gene3D G3DSA:1.10.10.630 315 391 1.6E-11 T 29-03-2018 IPR034829 DnaD-like domain CSW12_RS22515 9c8e85e0bc176a537f31e28632b188a8 469 Pfam PF07261 Replication initiation and membrane attachment 326 391 2.2E-9 T 29-03-2018 IPR006343 DnaD domain CSW12_RS12475 664d6967fb240f8834b4eb46ed788758 135 Pfam PF13140 Domain of unknown function (DUF3980) 47 133 2.3E-55 T 29-03-2018 IPR025044 Domain of unknown function DUF3980 CSW12_RS13285 4f7e5807c98460545b8045ee7626bc59 235 Gene3D G3DSA:2.160.10.10 20 235 0.0039 T 29-03-2018 CSW12_RS11905 e65ffccd96b338bea684d77123024cb4 101 SUPERFAMILY SSF54909 3 96 8.94E-32 T 29-03-2018 IPR011008 Dimeric alpha-beta barrel CSW12_RS11905 e65ffccd96b338bea684d77123024cb4 101 Pfam PF08803 Putative mono-oxygenase ydhR 4 98 4.6E-40 T 29-03-2018 IPR014910 Putative monooxygenase YdhR CSW12_RS09660 5727c1a69007c9cf866e8ffd5ba6669a 87 Gene3D G3DSA:1.20.1480.30 4 87 1.8E-4 T 29-03-2018 CSW12_RS18440 e882ee475386de54c058e4ff56449a39 386 Gene3D G3DSA:1.20.1170.10 29 386 1.8E-26 T 29-03-2018 CSW12_RS18440 e882ee475386de54c058e4ff56449a39 386 Pfam PF05791 Bacillus haemolytic enterotoxin (HBL) 42 215 1.4E-55 T 29-03-2018 IPR008414 Hemolysin BL-binding component GO:0009405|GO:0016020 CSW12_RS18440 e882ee475386de54c058e4ff56449a39 386 SUPERFAMILY SSF58100 39 385 1.31E-70 T 29-03-2018 CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 Gene3D G3DSA:3.40.710.10 32 317 1.1E-46 T 29-03-2018 CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 61 296 1.7E-65 T 29-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 SUPERFAMILY SSF56601 54 313 2.75E-68 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 SUPERFAMILY SSF56601 9 22 2.75E-68 T 29-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 91 102 8.5E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 171 184 8.5E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS18095 184957c5259e57a724b41e6e573fcfaf 317 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 161 8.5E-14 T 29-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CSW12_RS28650 373921e253ac307bfe89c6fca81823f8 471 Pfam PF13520 Amino acid permease 26 443 6.6E-64 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS28650 373921e253ac307bfe89c6fca81823f8 471 PIRSF PIRSF006060 10 471 1.9E-100 T 29-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CSW12_RS29410 9d6832906188f1916cf6fffaa1aa1369 602 Gene3D G3DSA:3.40.50.300 154 587 7.7E-5 T 29-03-2018 CSW12_RS26895 cb4209bec7f3963fccf284003e7dad58 210 Pfam PF03458 UPF0126 domain 92 166 1.2E-20 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CSW12_RS26895 cb4209bec7f3963fccf284003e7dad58 210 Pfam PF03458 UPF0126 domain 6 79 8.6E-20 T 29-03-2018 IPR005115 Uncharacterised domain UPF0126 CSW12_RS22805 1add9dcdd90d22dc1b71ddf2dfa8fd1b 211 Pfam PF08795 Putative papain-like cysteine peptidase (DUF1796) 12 155 1.0E-15 T 29-03-2018 IPR014903 Protein of unknown function DUF1796 CSW12_RS07745 744b7d1aa41dc5f77ae32975fb267bad 217 SUPERFAMILY SSF55073 75 216 1.73E-11 T 29-03-2018 IPR029787 Nucleotide cyclase CSW12_RS07745 744b7d1aa41dc5f77ae32975fb267bad 217 Pfam PF00990 Diguanylate cyclase, GGDEF domain 88 216 4.0E-10 T 29-03-2018 IPR000160 GGDEF domain CSW12_RS07745 744b7d1aa41dc5f77ae32975fb267bad 217 Gene3D G3DSA:3.30.70.270 66 217 1.2E-13 T 29-03-2018 CSW12_RS11890 57d80ca8209ab988852d3ee0e0f7cba6 132 Pfam PF07485 Domain of Unknown Function (DUF1259) 14 130 1.1E-30 T 29-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CSW12_RS03405 54a9444276a86058cb34c32d4e064cd8 122 Pfam PF13157 Protein of unknown function (DUF3992) 23 117 8.9E-37 T 29-03-2018 IPR025055 Protein of unknown function DUF3992 CSW12_RS09325 bf54d93b6b48f39c7eae062b7f32ccec 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 259 4.4E-17 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS09325 bf54d93b6b48f39c7eae062b7f32ccec 264 Gene3D G3DSA:1.10.3720.10 20 264 5.2E-27 T 29-03-2018 CSW12_RS09325 bf54d93b6b48f39c7eae062b7f32ccec 264 SUPERFAMILY SSF161098 70 256 2.88E-34 T 29-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CSW12_RS09325 bf54d93b6b48f39c7eae062b7f32ccec 264 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 17 264 6.5E-92 T 29-03-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CSW12_RS30330 1b46fdd13a9c64719fb89478fbe9e634 69 Gene3D G3DSA:1.20.5.320 5 68 3.6E-4 T 29-03-2018 CSW12_RS25225 1ccf02cb82c2ef37d04d1f1bc2ad28f1 318 Pfam PF08378 Nuclease-related domain 39 154 2.5E-18 T 29-03-2018 IPR011528 Nuclease-related domain, NERD CSW12_RS19085 fa22621f39bd2245023b6e4704750fc3 207 Pfam PF13021 Domain of unknown function (DUF3885) 165 202 4.1E-20 T 29-03-2018 IPR024976 Domain of unknown function DUF3885 CSW12_RS05215 6c488dbe20a8c25a38021df010558145 268 Pfam PF05709 Phage tail protein 24 266 1.0E-25 T 29-03-2018 IPR008841 Siphovirus-type tail component CSW12_RS16400 fd7051f117b6d5fdc6e46484e0e521f3 83 Pfam PF13135 Protein of unknown function (DUF3947) 2 83 1.7E-42 T 29-03-2018 IPR025039 Protein of unknown function DUF3947 CSW12_RS22430 3967e2936f9e5bb2811e6433b4b29252 69 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 1.5E-36 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CSW12_RS22430 3967e2936f9e5bb2811e6433b4b29252 69 Pfam PF14098 Small, acid-soluble spore protein I 3 67 2.8E-30 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CSW12_RS22430 3967e2936f9e5bb2811e6433b4b29252 69 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 22.058 T 29-03-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 CSW12_RS12960 7c84c482aee545d013e49557357c4aaf 220 Pfam PF12952 Domain of unknown function (DUF3841) 2 196 2.9E-46 T 29-03-2018 IPR024211 Protein of unknown function DUF3841 CSW12_RS21515 9b3dc97b91da5d5ba5f7e46181393cba 71 Pfam PF10750 Protein of unknown function (DUF2536) 1 68 5.2E-37 T 29-03-2018 IPR019686 Protein of unknown function DUF2536 CSW12_RS14525 f5c459e03c83bd8b47baf9160bcb2582 266 Pfam PF02361 Cobalt transport protein 3 223 4.4E-29 T 29-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CSW12_RS07260 6477c36cd54d4cfcb2166b08cc43e136 223 Pfam PF04402 Protein of unknown function (DUF541) 23 220 1.2E-38 T 29-03-2018 IPR007497 Protein of unknown function DUF541 CSW12_RS14400 8530b0d7e1b885781d8797a7c71cb016 168 Pfam PF11385 Protein of unknown function (DUF3189) 3 150 1.5E-49 T 29-03-2018 IPR021525 Protein of unknown function DUF3189 CSW12_RS14620 a0f1c4a9b219280e0627bdb4663fe369 334 Pfam PF08874 Domain of unknown function (DUF1835) 66 187 9.6E-31 T 29-03-2018 IPR014973 Protein of unknown function DUF1835 CSW12_RS14620 a0f1c4a9b219280e0627bdb4663fe369 334 Pfam PF12395 Protein of unknown function 225 329 1.3E-31 T 29-03-2018 IPR022123 Protein of unknown function DUF3658 CSW12_RS17965 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 93 117 3.7E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS17965 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 12 31 3.7E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS17965 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 65 87 3.7E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS17965 bc51a49fe6f175445d21b5d1a78bd1f2 226 PRINTS PR01837 MgtC/SapB protein signature 31 49 3.7E-40 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS17965 bc51a49fe6f175445d21b5d1a78bd1f2 226 Pfam PF02308 MgtC family 9 138 1.3E-34 T 29-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CSW12_RS01085 30e3874fa6b545af99a335b5dd5ec7d0 113 Pfam PF13108 Protein of unknown function (DUF3969) 9 111 4.7E-36 T 29-03-2018 IPR025083 Protein of unknown function DUF3969 CSW12_RS00915 bd98926b245814820a748c157a5a4c19 543 Pfam PF14266 Putative component of 'biosynthetic module' 40 525 8.6E-163 T 29-03-2018 IPR025647 Putative component of 'biosynthetic module' CSW12_RS14385 fe61a27d893750afd09302d28de66f8e 141 Pfam PF16219 Domain of unknown function (DUF4879) 30 140 1.0E-26 T 29-03-2018 IPR032624 Protein of unknown function DUF4879 CSW12_RS26695 38556ba1b7e40eb13baac9e2d5148070 351 SUPERFAMILY SSF81345 22 344 1.83E-83 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS26695 38556ba1b7e40eb13baac9e2d5148070 351 Gene3D G3DSA:1.10.3470.10 20 351 1.1E-64 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS26695 38556ba1b7e40eb13baac9e2d5148070 351 Pfam PF01032 FecCD transport family 35 344 2.1E-88 T 29-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CSW12_RS30445 2909577d5becadd0cd48a8341f290ca2 238 Pfam PF14283 Domain of unknown function (DUF4366) 77 203 6.9E-20 T 29-03-2018 IPR025376 Domain of unknown function DUF4366 CSW12_RS14865 9cd196a6c4a428afc1e628e0aa684c78 250 Pfam PF13649 Methyltransferase domain 50 131 1.1E-12 T 29-03-2018 CSW12_RS14865 9cd196a6c4a428afc1e628e0aa684c78 250 Gene3D G3DSA:3.40.50.150 31 242 1.5E-18 T 29-03-2018 CSW12_RS14865 9cd196a6c4a428afc1e628e0aa684c78 250 SUPERFAMILY SSF53335 34 250 3.32E-22 T 29-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CSW12_RS01520 4102a6b3b183f1d7639a7479e1a77f39 84 Gene3D G3DSA:2.40.50.100 5 75 7.8E-7 T 29-03-2018 CSW12_RS31135 531ca26ff55087fe6f7825958e105a22 188 SUPERFAMILY SSF159941 1 182 9.42E-51 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS31135 531ca26ff55087fe6f7825958e105a22 188 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 3 179 1.1E-48 T 29-03-2018 IPR012912 Plasmid pRiA4b, Orf3 CSW12_RS31135 531ca26ff55087fe6f7825958e105a22 188 Gene3D G3DSA:3.10.290.30 1 182 5.8E-49 T 29-03-2018 IPR024047 Protein MM3350-like domain CSW12_RS21430 458b9f8f465b3d41c6978d8201d15053 134 Pfam PF07681 DoxX 7 87 6.1E-21 T 29-03-2018 IPR032808 DoxX family CSW12_RS06790 dc13cbe68be8f225e6d4b290cca4fa1d 89 Pfam PF13059 Protein of unknown function (DUF3992) 9 87 3.6E-53 T 29-03-2018 IPR025035 Protein of unknown function DUF3922 CSW12_RS23785 fcf25ef15599fe64f648abc247a1223f 223 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 208 1.6E-67 T 29-03-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 CSW12_RS11880 ef23d5834632b1a9257a0cd8b24efdb9 156 Gene3D G3DSA:1.10.287.540 21 143 0.0042 T 29-03-2018 CSW12_RS20340 98fce161777110665f29fb2cc7e270de 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 7 141 1.5E-62 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CSW12_RS20340 98fce161777110665f29fb2cc7e270de 144 Pfam PF06491 Disulphide isomerase 7 141 2.8E-61 T 29-03-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family CSW12_RS06705 411e774e8c24c4614c5451dabe76d8e4 66 Pfam PF13046 Protein of unknown function (DUF3906) 1 64 1.4E-31 T 29-03-2018 IPR024998 Protein of unknown function DUF3906 CSW12_RS05565 3da4483af6141fce40f15f9832b9d7ad 386 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 338 362 - T 29-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CSW12_RS05565 3da4483af6141fce40f15f9832b9d7ad 386 Pfam PF01098 Cell cycle protein 14 381 1.1E-88 T 29-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CSW12_RS15210 2ffc737f36baf59d81f2c4471201e25f 152 Pfam PF16723 Domain of unknown function (DUF5065) 2 152 7.9E-56 T 29-03-2018 IPR031998 Protein of unknown function DUF5065 CSW12_RS10795 7f9f50f85dfba3fc6e4ea9c463b1e04a 445 Pfam PF12791 Anti-sigma factor N-terminus 8 51 7.7E-15 T 29-03-2018 IPR024449 Anti-sigma factor RsgI, N-terminal CSW12_RS10670 959dc96b8879265580f2c6f34d66f5a7 140 Pfam PF04657 Putative inner membrane exporter, YdcZ 2 136 2.1E-30 T 29-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CSW12_RS09445 738e11d9ea9968d323e084291c3b9d4b 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 3.5E-63 T 29-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CSW12_RS11900 34785e859ad94e081ce0a67a4cb4d2d4 116 Pfam PF13564 DoxX-like family 9 108 5.2E-14 T 29-03-2018 IPR032808 DoxX family CSW12_RS06520 84fc70993368c530db9d4ebdce57cf01 447 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 36 418 1.2E-112 T 29-03-2018 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CSW12_RS06520 84fc70993368c530db9d4ebdce57cf01 447 Pfam PF02386 Cation transport protein 43 427 9.9E-50 T 29-03-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CSW12_RS17665 24cdfb62fcc445bcb1051c085139e191 298 Pfam PF03773 Predicted permease 11 293 8.5E-80 T 29-03-2018 IPR005524 Predicted permease DUF318 CSW12_RS19185 081dc9f012f7f0955306412a624b3cf4 103 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 100 1.6E-23 T 29-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CSW12_RS02980 71b8b751fe8c5cdc038a8263898f66ef 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 1.2E-23 T 29-03-2018 IPR010035 ThiS, thiamine-biosynthesis CSW12_RS02980 71b8b751fe8c5cdc038a8263898f66ef 67 SUPERFAMILY SSF54285 3 66 1.05E-17 T 29-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CSW12_RS02980 71b8b751fe8c5cdc038a8263898f66ef 67 Pfam PF02597 ThiS family 6 67 7.7E-15 T 29-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CSW12_RS02980 71b8b751fe8c5cdc038a8263898f66ef 67 Gene3D G3DSA:3.10.20.30 2 67 6.8E-20 T 29-03-2018 IPR012675 Beta-grasp domain CSW12_RS23615 d07bb624138da7b0c034662f3c871d88 689 SUPERFAMILY SSF53649 399 576 6.11E-20 T 29-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CSW12_RS23615 d07bb624138da7b0c034662f3c871d88 689 Pfam PF00884 Sulfatase 327 622 2.4E-32 T 29-03-2018 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CSW12_RS23615 d07bb624138da7b0c034662f3c871d88 689 Gene3D G3DSA:3.40.720.10 319 630 1.3E-25 T 29-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CSW12_RS22670 5a0d653f527e8bdba13c0297c5386c89 101 Pfam PF14007 YtpI-like protein 5 90 4.7E-35 T 29-03-2018 IPR025618 YtpI-like protein CSW12_RS12685 4f2c6bf2bc9e197bd7fc172ea14cea5c 276 Pfam PF04294 VanW like protein 72 204 2.1E-41 T 29-03-2018 IPR007391 Vancomycin resistance VanW CSW12_RS15930 0f6f741403f2c6d145ea70449c2ea7e4 298 Pfam PF02517 CAAX protease self-immunity 141 228 1.6E-12 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS16450 fc1a83acbc4cc647e9ba4d707efac296 59 ProDom PD052277 YOZD 1 56 3.0E-23 T 29-03-2018 CSW12_RS16450 fc1a83acbc4cc647e9ba4d707efac296 59 Pfam PF14162 YozD-like protein 1 56 3.3E-29 T 29-03-2018 IPR025545 YozD-like protein CSW12_RS21585 d5e218b186fdbd69d7a855fd54495380 355 Pfam PF01594 AI-2E family transporter 33 345 1.1E-67 T 29-03-2018 IPR002549 Transmembrane protein TqsA-like CSW12_RS24950 e2902e34c1b0da1c8e747b889e714a0d 147 Pfam PF13123 Protein of unknown function (DUF3978) 1 144 2.0E-96 T 29-03-2018 IPR025010 Protein of unknown function DUF3978 CSW12_RS09070 2010718e8561c3389fd4380a57c0d1ae 212 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 39 197 9.3E-6 T 29-03-2018 IPR003740 Uncharacterised membrane protein YitT CSW12_RS16210 0344a5e2a2ce45fa20cadf4a71bec896 61 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 1.0E-23 T 29-03-2018 IPR018690 Protein of unknown function DUF2187 CSW12_RS07910 659089724af875a17ad9455d65bbda27 98 Pfam PF11256 Protein of unknown function (DUF3055) 5 84 1.1E-34 T 29-03-2018 IPR021415 Protein of unknown function DUF3055 CSW12_RS18840 3f29867955c614810c5a8623edf2d567 369 Pfam PF12698 ABC-2 family transporter protein 19 360 5.1E-28 T 29-03-2018 CSW12_RS05755 0d41aef7bd0b46867d03eeb33b24bfe4 499 Pfam PF02652 L-lactate permease 2 491 1.2E-61 T 29-03-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 CSW12_RS29480 1d7998b7c47a002e43d79a52c9a51059 375 SUPERFAMILY SSF56973 202 299 8.11E-8 T 29-03-2018 CSW12_RS29480 1d7998b7c47a002e43d79a52c9a51059 375 Gene3D G3DSA:2.170.15.10 205 330 2.3E-6 T 29-03-2018 CSW12_RS29310 c228b3d5720b4e8e2114c992b01c660f 388 Gene3D G3DSA:3.30.420.40 9 219 2.6E-7 T 29-03-2018 CSW12_RS05420 d40d573ff4acdd9e277985715917b2fb 248 Pfam PF12227 Protein of unknown function (DUF3603) 35 248 4.2E-113 T 29-03-2018 IPR020909 UPF0736 CSW12_RS05420 d40d573ff4acdd9e277985715917b2fb 248 Hamap MF_01860 UPF0736 protein . 1 248 51.639 T 29-03-2018 IPR020909 UPF0736 CSW12_RS15165 07a5005a0389fa3b0d3ea977096a18d0 439 Pfam PF03222 Tryptophan/tyrosine permease family 40 425 1.5E-17 T 29-03-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 CSW12_RS20685 1a7e6e055cbff353409f46a3ac512cc5 197 Pfam PF13346 ABC-2 family transporter protein 3 193 2.2E-34 T 29-03-2018 IPR025699 ABC-2 membrane transporter-like CSW12_RS13430 dd6175687df36716ac0f1c4d788230b4 108 Pfam PF12986 Domain of unknown function (DUF3870) 8 99 2.8E-33 T 29-03-2018 IPR024617 Domain of unknown function DUF3870 CSW12_RS24970 914f5ad47e5c91c99cc74d6118786f40 300 Pfam PF00892 EamA-like transporter family 150 282 1.4E-14 T 29-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CSW12_RS24970 914f5ad47e5c91c99cc74d6118786f40 300 SUPERFAMILY SSF103481 191 286 9.68E-9 T 29-03-2018 CSW12_RS06680 c58894065ccc3e5e695f48cf7d3dc4c7 47 Pfam PF10055 Uncharacterized small protein (DUF2292) 10 46 4.7E-19 T 29-03-2018 IPR018743 Protein of unknown function DUF2292 CSW12_RS13090 a41b5a4729dfc1875e4233712687f1f6 273 Pfam PF14279 HNH endonuclease 4 53 2.3E-13 T 29-03-2018 IPR029471 HNH endonuclease 5 CSW12_RS12450 85ca9f48fb05c827d38580e76b1451c1 104 Pfam PF13031 Protein of unknown function (DUF3892) 35 102 4.6E-17 T 29-03-2018 IPR024997 Protein of unknown function DUF3892 CSW12_RS26065 cba9721b5d5aeafc1137ceefcd2cdb96 260 Pfam PF13057 Protein of unknown function (DUF3919) 37 253 4.3E-43 T 29-03-2018 IPR025031 Protein of unknown function DUF3919 CSW12_RS17800 f8fb82f87510db58c975bad05fdb7ad7 121 Pfam PF13141 Protein of unknown function (DUF3979) 8 119 7.0E-76 T 29-03-2018 IPR025045 Protein of unknown function DUF3979 CSW12_RS18110 bb9c1b7a260b699f6b19c9160edc8cc5 148 Gene3D G3DSA:1.20.1170.10 25 148 8.8E-5 T 29-03-2018 CSW12_RS05640 450dc85c9edd6c77938f0138f2cf95cb 154 Pfam PF10612 Spore coat protein Z 1 149 5.0E-46 T 29-03-2018 IPR019593 Spore coat protein Z/Y CSW12_RS17660 5e723a2411bf41dbe8c9576a5b52c8c5 289 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 283 2.1E-68 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 CSW12_RS17660 5e723a2411bf41dbe8c9576a5b52c8c5 289 Pfam PF09323 Domain of unknown function (DUF1980) 1 193 2.8E-65 T 29-03-2018 IPR015402 Protein of unknown function DUF1980 CSW12_RS14215 7e63a25dbf7ec629ca8e4282699f6db7 123 Pfam PF14176 YxiJ-like protein 10 118 4.3E-51 T 29-03-2018 IPR025551 YxiJ-like protein CSW12_RS05535 a51c43a62b7c5a530e9ddfd4a978cf96 123 Hamap MF_01861 UPF0738 protein . 3 123 28.69 T 29-03-2018 IPR020908 Uncharacterised protein family UPF0738 CSW12_RS11095 60fa6697eda09a32f6fc4d8f79c3361b 257 Pfam PF13704 Glycosyl transferase family 2 10 96 5.9E-8 T 29-03-2018 CSW12_RS25240 83478fcdb3ae89a34292a84a27d2feb6 321 Pfam PF16103 Domain of unknown function (DUF4822) 197 319 2.2E-52 T 29-03-2018 IPR032247 Domain of unknown function DUF4822 CSW12_RS25240 83478fcdb3ae89a34292a84a27d2feb6 321 Pfam PF16103 Domain of unknown function (DUF4822) 57 176 2.4E-51 T 29-03-2018 IPR032247 Domain of unknown function DUF4822 CSW12_RS05225 c756a687a99e95688ba4781b9a70b82c 714 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 20 334 2.1E-55 T 29-03-2018 IPR007119 Phage minor structural protein, N-terminal domain CSW12_RS05225 c756a687a99e95688ba4781b9a70b82c 714 Pfam PF06605 Prophage endopeptidase tail 64 340 3.2E-23 T 29-03-2018 IPR010572 Prophage tail endopeptidase CSW12_RS27485 bdf22a7d092633ebd4c6c0b52e001de0 59 Pfam PF10764 Inhibitor of sigma-G Gin 8 52 1.8E-18 T 29-03-2018 IPR019700 Anti-sigma-G factor Gin CSW12_RS10355 8e1d0efb37598e6de533fc945971fbfb 73 Pfam PF16723 Domain of unknown function (DUF5065) 24 70 2.9E-6 T 29-03-2018 IPR031998 Protein of unknown function DUF5065 CSW12_RS20600 2b24eae4c8175ea976c938d123a7b0cd 133 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 4 133 9.0E-14 T 29-03-2018 CSW12_RS28305 3006a88dcf65b52bcbfe19573b2d0808 168 Pfam PF07681 DoxX 16 114 1.9E-10 T 29-03-2018 IPR032808 DoxX family CSW12_RS12565 0b9bc3e0a877fe18594b8119fb86e758 168 Pfam PF13042 Protein of unknown function (DUF3902) 2 162 6.4E-77 T 29-03-2018 IPR025001 Protein of unknown function DUF3902 CSW12_RS12625 132cbcb99b3d4516f99666bf8ba759bc 175 Pfam PF11193 Protein of unknown function (DUF2812) 15 125 1.1E-29 T 29-03-2018 IPR021359 Protein of unknown function DUF2812 CSW12_RS05660 f198921e4588736d035ddd02a656f98a 155 Pfam PF10612 Spore coat protein Z 4 152 2.4E-41 T 29-03-2018 IPR019593 Spore coat protein Z/Y CSW12_RS25325 01b00ca74b9010c8614c93bb92965c97 230 Pfam PF04172 LrgB-like family 14 226 1.6E-65 T 29-03-2018 IPR007300 CidB/LrgB family CSW12_RS13620 7ff2186074d75419ab3656822f5093a8 281 Pfam PF02517 CAAX protease self-immunity 125 226 3.4E-12 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS30215 5e596042a502ee648221f84ef631d538 90 Gene3D G3DSA:1.10.10.10 10 86 7.5E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS16350 f2f84db0ea896875e563dd25291e23f7 111 Pfam PF08863 YolD-like protein 19 110 6.1E-21 T 29-03-2018 IPR014962 YolD-like protein CSW12_RS06500 ca5706b536ae4ad8592f1e4734fc0a9d 143 Pfam PF14184 Regulatory protein YrvL 15 140 1.6E-38 T 29-03-2018 IPR025912 Regulatory protein YrvL CSW12_RS03255 cd0f331e5c84dd81acfe7f8c06584ba8 146 Gene3D G3DSA:3.30.1460.10 9 133 5.9E-4 T 29-03-2018 CSW12_RS14485 26c4a3ea20f308af3ebb22830267a424 154 Gene3D G3DSA:2.60.120.40 19 154 9.8E-13 T 29-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CSW12_RS24445 9ec0f1f12254d013692b281bd803e0f9 153 Pfam PF04463 Protein of unknown function (DUF523) 2 146 2.2E-43 T 29-03-2018 IPR007553 Domain of unknown function DUF523 CSW12_RS19810 0d562c99861505b41f5ff3cb1fdd690b 185 Pfam PF14179 YppG-like protein 68 183 1.2E-25 T 29-03-2018 IPR025555 YppG-like protein CSW12_RS12025 26cb16444aafcda6a5eaf208bc551ddb 120 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 5 112 1.0E-39 T 29-03-2018 IPR018745 Domain of unknown function DUF2294 CSW12_RS23915 5f950328276ad93070d331259a37ebf2 659 PIRSF PIRSF018968 1 653 2.8E-126 T 29-03-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 CSW12_RS23915 5f950328276ad93070d331259a37ebf2 659 Pfam PF02687 FtsX-like permease family 84 173 7.7E-7 T 29-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CSW12_RS03965 26da8661cdf3372aad5b70895d5e4af4 55 Gene3D G3DSA:1.10.10.60 2 49 8.8E-8 T 29-03-2018 CSW12_RS29925 8e79b5252d25eba40c8385761cf3dc9c 158 Gene3D G3DSA:2.60.40.10 40 153 3.4E-6 T 29-03-2018 IPR013783 Immunoglobulin-like fold CSW12_RS04730 3175bd071ef0ceb7ef145df7421b1cb7 106 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 27 92 2.7E-22 T 29-03-2018 IPR018656 Domain of unknown function DUF2087 CSW12_RS19335 282f676802d40a44a4461b85b056d9d8 229 Pfam PF02108 Flagellar assembly protein FliH 85 197 6.8E-8 T 29-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CSW12_RS06360 e1be166095cc7106c0862ab15dceb30f 60 Pfam PF13052 Protein of unknown function (DUF3913) 2 58 4.0E-44 T 29-03-2018 IPR025024 Protein of unknown function DUF3913 CSW12_RS28845 0e7c0980dceddd56db3d2327b6f11113 249 Pfam PF02517 CAAX protease self-immunity 131 216 7.1E-18 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS24945 290425be0bc89f3cb9f62972de1e91ea 204 Pfam PF09335 SNARE associated Golgi protein 29 154 6.4E-18 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS18310 e7bfb520b48c9494f8db445b3db5eee3 431 Pfam PF13687 Domain of unknown function (DUF4153) 230 389 2.0E-7 T 29-03-2018 IPR025291 Protein of unknown function DUF4153 CSW12_RS31060 5b2b31e0c98a64fd8c80d80dd69bc21b 79 ProDom PD275078 PLASMID PXO2-72/BXB0098/GBAA_PXO2_0098 4 65 0.009 T 29-03-2018 IPR020250 Uncharacterised protein family, plasmid pXO2-72 CSW12_RS11425 12727b609c815b98ec131d104a3dade1 127 Pfam PF04434 SWIM zinc finger 51 82 4.8E-7 T 29-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CSW12_RS22655 49b79b2be6c1856252ca5b892222fb25 114 Pfam PF14034 Sporulation protein YtrH 14 111 2.8E-37 T 29-03-2018 IPR025689 Sporulation protein YtrH CSW12_RS16890 cc833947fce569a0ed0865fa1c96943b 404 Pfam PF05975 Bacterial ABC transporter protein EcsB 4 388 1.5E-64 T 29-03-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 CSW12_RS23765 4a4c460234f3fee42901f0a89438c86c 192 Pfam PF17294 Uncharacterised lipoprotein family 28 191 4.0E-51 T 29-03-2018 IPR035253 Putative lipoprotein, bacteria CSW12_RS21105 ae2674e8d62015dcc024d7c592020cee 47 Pfam PF14006 YqzL-like protein 3 46 3.2E-20 T 29-03-2018 IPR025617 YqzL-like protein CSW12_RS23475 cf10836fab83996b0b33cb0a635587ae 358 Pfam PF10776 Protein of unknown function (DUF2600) 24 353 2.5E-153 T 29-03-2018 IPR019712 Protein of unknown function DUF2600 KEGG: 00909+4.2.3.13|MetaCyc: PWY-5773|MetaCyc: PWY-5828 CSW12_RS12090 c6f30c416fd487e20a8ddab05312f81f 128 Pfam PF11181 Heat induced stress protein YflT 11 108 1.3E-31 T 29-03-2018 IPR025889 General stress protein 17M-like domain CSW12_RS17605 3e38af6c3a884a3144621bc831adb6a2 214 Pfam PF13787 Protein of unknown function with HXXEE motif 44 154 3.6E-15 T 29-03-2018 IPR025671 Protein of unknown function with HXXEE motif CSW12_RS14100 20d0d1566cb71b4ef8b27e63de6bcb04 122 Pfam PF13788 Domain of unknown function (DUF4180) 10 118 2.0E-42 T 29-03-2018 IPR025438 Domain of unknown function DUF4180 CSW12_RS23625 8b1d548294968e60cd53467b4d92f96b 98 Pfam PF13143 Protein of unknown function (DUF3986) 3 89 1.6E-32 T 29-03-2018 IPR025047 Protein of unknown function DUF3986 CSW12_RS06475 ac9cb6359122f15829aa460696a7c9d1 157 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 49 89 6.4E-8 T 29-03-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger CSW12_RS07020 3f52c647afdaa3ab42282c9f77054090 187 Pfam PF02517 CAAX protease self-immunity 96 179 5.0E-11 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS23030 ceda74eb664b51308306323548d9bb85 78 Pfam PF13133 Protein of unknown function (DUF3949) 15 75 4.6E-33 T 29-03-2018 IPR025032 Protein of unknown function DUF3949 CSW12_RS23030 ceda74eb664b51308306323548d9bb85 78 Gene3D G3DSA:1.20.1560.10 1 46 5.4E-5 T 29-03-2018 CSW12_RS29005 7e43dfd8719e073ab3492e29d519a400 263 Pfam PF03567 Sulfotransferase family 23 258 9.9E-11 T 29-03-2018 IPR005331 Sulfotransferase GO:0008146|GO:0016021 CSW12_RS11220 57854e1586d63eff4b917b4e9a95f224 279 Pfam PF10978 Protein of unknown function (DUF2785) 80 253 1.1E-48 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 CSW12_RS17770 1e341d603729aac502146a815d5a391a 63 Pfam PF13035 Protein of unknown function (DUF3896) 1 61 4.5E-42 T 29-03-2018 IPR024994 Protein of unknown function DUF3896 CSW12_RS12445 4f5d5353a14a4c2034fd9a172fdade86 274 Pfam PF10978 Protein of unknown function (DUF2785) 81 249 2.0E-51 T 29-03-2018 IPR021247 Protein of unknown function DUF2785 CSW12_RS23250 ce335e9b6eed6393db83c3d126042ac4 75 Pfam PF13119 Domain of unknown function (DUF3973) 1 40 1.7E-29 T 29-03-2018 IPR025003 Domain of unknown function DUF3973 CSW12_RS07755 8114e7bacd04cd1aff2c329abeef0973 152 Pfam PF14177 YkyB-like protein 16 137 4.1E-56 T 29-03-2018 IPR025552 YkyB-like protein CSW12_RS13460 1d6545d9e03172f92d43cdc396bd0ab3 201 Pfam PF09335 SNARE associated Golgi protein 30 156 1.1E-25 T 29-03-2018 IPR032816 SNARE associated Golgi protein CSW12_RS02425 5c7f92910ec424c8d8940963dd3ea42a 40 Pfam PF13137 Protein of unknown function (DUF3983) 5 38 2.2E-23 T 29-03-2018 IPR025041 Protein of unknown function DUF3983 CSW12_RS19640 f74888c76a217626812adf05e3df148b 404 Pfam PF04932 O-Antigen ligase 193 331 1.1E-18 T 29-03-2018 IPR007016 O-antigen ligase-related CSW12_RS14665 efe183a4a700691ccb12bb8a07c75aea 87 Pfam PF13073 Protein of unknown function (DUF3937) 8 79 3.2E-48 T 29-03-2018 IPR025068 Protein of unknown function DUF3937 CSW12_RS09400 7f6a80289101ee21915842fbd247d5b4 121 Hamap MF_01143 Holin-like protein CidA [cidA]. 1 118 24.115 T 29-03-2018 IPR023760 Holin-like protein CidA GO:0016021 CSW12_RS09400 7f6a80289101ee21915842fbd247d5b4 121 Pfam PF03788 LrgA family 18 109 1.5E-30 T 29-03-2018 IPR005538 LrgA/CidA family GO:0016021 CSW12_RS29745 f9711b644a73fef6fdd3e287f225fea8 314 Gene3D G3DSA:1.10.10.10 53 131 1.9E-4 T 29-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CSW12_RS13260 0453321aaf02080fd01faa23cfbb4cd0 223 Gene3D G3DSA:3.40.190.10 6 215 0.0028 T 29-03-2018 CSW12_RS13260 0453321aaf02080fd01faa23cfbb4cd0 223 Pfam PF14172 Domain of unknown function (DUF4309) 86 212 1.3E-42 T 29-03-2018 IPR025453 Protein of unknown function DUF4309 CSW12_RS09385 28774055e133b3e501dd0eb130cd2b17 66 Pfam PF13043 Domain of unknown function (DUF3903) 25 64 3.2E-25 T 29-03-2018 IPR025000 Protein of unknown function DUF3903 CSW12_RS22275 d7a39a30e78b99bd441168aec8e56d96 234 Pfam PF12730 ABC-2 family transporter protein 4 182 7.3E-9 T 29-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CSW12_RS07925 24449481e848fb9894bfad374df9a7a6 42 Pfam PF13790 SR1 protein 1 38 1.4E-16 T 29-03-2018 IPR025236 SR1 protein CSW12_RS29815 7b1c9e25008253297162d05fe60ad325 205 Pfam PF13814 Replication-relaxation 16 169 2.9E-14 T 29-03-2018 IPR025855 Plasmid replication-relaxation CSW12_RS21015 1f5bf3fe687c8188aeaa96d292445087 277 SUPERFAMILY SSF81345 3 267 1.01E-37 T 29-03-2018 IPR029022 ABC transporter, BtuC-like CSW12_RS21015 1f5bf3fe687c8188aeaa96d292445087 277 Gene3D G3DSA:1.10.3470.10 2 277 2.2E-28 T 29-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CSW12_RS21015 1f5bf3fe687c8188aeaa96d292445087 277 Pfam PF00950 ABC 3 transport family 7 270 5.4E-64 T 29-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CSW12_RS26010 48d69ed05cbbf8d2251236af70868f2b 132 Pfam PF14271 Domain of unknown function (DUF4359) 16 119 5.0E-18 T 29-03-2018 IPR025578 Protein of unknown function DUF4359 CSW12_RS11450 5dcc7ea83d342dfb41e669a91270a1b8 79 Pfam PF13396 Phospholipase_D-nuclease N-terminal 31 73 1.3E-11 T 29-03-2018 IPR027379 Cardiolipin synthase N-terminal CSW12_RS30435 8ecc58e387b2e0bcdcdc6a4d13326267 577 Pfam PF09479 Listeria-Bacteroides repeat domain (List_Bact_rpt) 226 287 8.4E-7 T 29-03-2018 IPR013378 Listeria/Bacterioides repeat CSW12_RS29885 2f25736930311d0a97f232b58dbb3eea 365 Pfam PF03845 Spore germination protein 8 323 2.3E-77 T 29-03-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 CSW12_RS11855 e67bb2c31681b0d24b36a0e0d591d107 292 Pfam PF02517 CAAX protease self-immunity 152 247 3.4E-9 T 29-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CSW12_RS05175 bdadd05fa9e09a0a8a3f9b008e631258 86 Pfam PF05135 Phage gp6-like head-tail connector protein 5 61 1.0E-4 T 29-03-2018 IPR021146 Phage gp6-like head-tail connector protein CSW12_RS19665 99ad781d4b6504c67b655a1644783357 397 Pfam PF01757 Acyltransferase family 6 353 1.6E-29 T 29-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CSW12_RS15565 22bbbab62eba2cde9ec3a68145c8b674 252 Pfam PF01925 Sulfite exporter TauE/SafE 11 245 1.9E-43 T 29-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CSW12_RS15115 10ddbc78712acc1a046221cbc37e9ec4 365 Pfam PF09992 Phosphodiester glycosidase 152 332 9.4E-37 T 29-03-2018 IPR018711 Phosphodiester glycosidase CSW12_RS04085 8c17cb24049e722f791dc23818059433 88 Pfam PF14157 YmzC-like protein 28 87 3.8E-28 T 29-03-2018 IPR025448 YmzC-like protein CSW12_RS19320 7e5bc3dc67b8111ff5c0faafb1a8b8c2 375 Pfam PF02120 Flagellar hook-length control protein FliK 271 341 2.1E-8 T 29-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CSW12_RS26665 16d7b026f1b39eab2323bfe3f6a6edb1 224 Pfam PF02163 Peptidase family M50 125 181 2.7E-9 T 29-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CSW12_RS13975 74c2ede2e745a1915b89867038d79c13 134 Gene3D G3DSA:1.20.810.10 3 134 4.4E-4 T 29-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CSW12_RS05770 08d844bd0c9b675e5f1f8617581fa129 206 Pfam PF10042 Uncharacterized conserved protein (DUF2278) 3 191 3.8E-66 T 29-03-2018 IPR019268 Protein of unknown function DUF2278 CSW12_RS20670 c15ec5a5ab5d240826ff59383c09a95d 85 Pfam PF13126 Protein of unknown function (DUF3975) 1 80 3.5E-46 T 29-03-2018 IPR025015 Protein of unknown function DUF3975 CSW12_RS22615 a279b8a0505a9e4116952a1183848686 129 Pfam PF04186 FxsA cytoplasmic membrane protein 7 114 3.5E-35 T 29-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CSW12_RS28355 eb9b491d49a095a90f22e5f8d1ae678a 572 Pfam PF13139 Domain of unknown function (DUF3981) 13 126 4.1E-73 T 29-03-2018 IPR025043 Domain of unknown function DUF3981 CSW12_RS16915 ec6dfa7f03dbbf5059def416f8c39123 161 Pfam PF11188 Protein of unknown function (DUF2975) 33 161 2.1E-36 T 29-03-2018 IPR021354 Protein of unknown function DUF2975 CSW12_RS08070 b3ab3f236ff2dc0390e8ad8e515e127d 147 Pfam PF14071 Putative coat protein 13 147 7.1E-45 T 29-03-2018 IPR025953 Putative coat protein YlbD CSW12_RS19730 07fcd97becd12445d5ae0b983a810c1b 84 Pfam PF13082 Protein of unknown function (DUF3931) 1 66 4.8E-50 T 29-03-2018 IPR025078 Protein of unknown function DUF3931