locus-tag	class	description
L6495_RS00010	COG0592	DNA-directed DNA polymerase activity
L6495_RS00015	COG2501	S4 domain
L6495_RS00025	COG0187	DNA topoisomerase II activity
L6495_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L6495_RS00065	COG0516	GMP reductase activity
L6495_RS00065	COG0517	IMP dehydrogenase activity
L6495_RS00070	COG1686	Belongs to the peptidase S11 family
L6495_RS00100	COG1428	Deoxynucleoside kinase
L6495_RS00105	COG1428	Deoxynucleoside kinase
L6495_RS00110	COG1335	isochorismatase
L6495_RS00115	COG0590	tRNA wobble adenosine to inosine editing
L6495_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L6495_RS00180	COG1982	Orn Lys Arg decarboxylase major
L6495_RS00190	COG0470	DNA polymerase III
L6495_RS00195	COG1774	PSP1 C-terminal conserved region
L6495_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L6495_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L6495_RS00220	COG2002	toxin-antitoxin pair type II binding
L6495_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6495_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6495_RS00230	COG0084	hydrolase, TatD family'
L6495_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L6495_RS00250	COG4466	Protein conserved in bacteria
L6495_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L6495_RS00270	COG0251	oxidation-reduction process
L6495_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L6495_RS00305	COG2002	toxin-antitoxin pair type II binding
L6495_RS00310	COG2244	polysaccharide biosynthetic process
L6495_RS00315	COG3956	TIGRFAM MazG family protein
L6495_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L6495_RS00340	COG1098	S1 RNA binding domain
L6495_RS00355	COG2208	phosphoserine phosphatase activity
L6495_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L6495_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L6495_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6495_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L6495_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
L6495_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6495_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L6495_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L6495_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L6495_RS00420	COG1396	sequence-specific DNA binding
L6495_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L6495_RS00515	COG3880	PFAM UvrB UvrC protein
L6495_RS00525	COG0542	response to heat
L6495_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L6495_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
L6495_RS00560	COG1045	serine acetyltransferase
L6495_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L6495_RS00580	COG3688	RNA-binding protein containing a PIN domain
L6495_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L6495_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
L6495_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L6495_RS00625	COG2813	Specifically methylates the guanine in position
L6495_RS00640	COG1358	cellular component organization or biogenesis
L6495_RS00715	COG0255	Belongs to the universal ribosomal protein uL29 family
L6495_RS00775	COG0201	protein transport
L6495_RS00785	COG0024	Methionine aminopeptidase
L6495_RS00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L6495_RS00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L6495_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L6495_RS00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6495_RS00860	COG0489	protein tyrosine kinase activity
L6495_RS00870	COG2194	sulfuric ester hydrolase activity
L6495_RS00875	COG0726	polysaccharide deacetylase
L6495_RS00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L6495_RS00960	COG4856	YbbR-like protein
L6495_RS00980	COG0596	Alpha beta hydrolase
L6495_RS01000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L6495_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS01035	COG2011	ABC-type metal ion transport system permease component
L6495_RS01045	COG1464	Belongs to the NlpA lipoprotein family
L6495_RS01050	COG0604	alcohol dehydrogenase
L6495_RS01060	COG0277	FAD linked oxidase domain protein
L6495_RS01065	COG2271	Major facilitator Superfamily
L6495_RS01075	COG2814	Major facilitator Superfamily
L6495_RS01090	COG0601	transmembrane transport
L6495_RS01095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6495_RS01100	COG0444	Belongs to the ABC transporter superfamily
L6495_RS01105	COG4608	Belongs to the ABC transporter superfamily
L6495_RS01110	COG4166	transmembrane transport
L6495_RS01120	COG2207	Transcriptional regulator
L6495_RS01130	COG1309	transcriptional regulator
L6495_RS01140	COG4166	transmembrane transport
L6495_RS01145	COG4166	transmembrane transport
L6495_RS01150	COG0656	L-ascorbic acid biosynthetic process
L6495_RS01155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6495_RS01170	COG4149	molybdate abc transporter
L6495_RS01175	COG0725	ABC transporter, periplasmic molybdate-binding protein
L6495_RS01180	COG1910	domain protein
L6495_RS01195	COG0697	spore germination
L6495_RS01210	COG0204	Acyl-transferase
L6495_RS01220	COG1609	Transcriptional regulator
L6495_RS01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS01240	COG0084	hydrolase, TatD family'
L6495_RS01250	COG5298	Protein conserved in bacteria
L6495_RS01275	COG0488	(ABC) transporter
L6495_RS01280	COG4585	Histidine kinase
L6495_RS01285	COG2197	response regulator
L6495_RS01290	COG1131	(ABC) transporter
L6495_RS01295	COG1511	domain protein
L6495_RS01295	COG0842	Transport permease protein
L6495_RS01300	COG0842	Transport permease protein
L6495_RS01315	COG0747	negative chemotaxis
L6495_RS01320	COG0601	transmembrane transport
L6495_RS01325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6495_RS01330	COG0444	Belongs to the ABC transporter superfamily
L6495_RS01335	COG4608	Belongs to the ABC transporter superfamily
L6495_RS01340	COG0561	phosphatase activity
L6495_RS01370	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L6495_RS01375	COG0179	Fumarylacetoacetate (FAA) hydrolase
L6495_RS01385	COG2814	Major facilitator Superfamily
L6495_RS01395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L6495_RS01405	COG4294	response to UV
L6495_RS01410	COG0705	Rhomboid family
L6495_RS01410	COG0457	Tetratricopeptide repeat
L6495_RS01420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L6495_RS01425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L6495_RS01430	COG0864	Transcriptional regulator
L6495_RS01435	COG2337	Toxic component of a toxin-antitoxin (TA) module
L6495_RS01440	COG2183	response to ionizing radiation
L6495_RS01535	COG0802	atpase or kinase
L6495_RS01540	COG1214	PFAM Peptidase M22, glycoprotease
L6495_RS01545	COG0456	acetyltransferase
L6495_RS01555	COG0488	(ABC) transporter
L6495_RS01570	COG1266	CAAX protease self-immunity
L6495_RS01590	COG2252	PERMEase
L6495_RS01600	COG5002	protein histidine kinase activity
L6495_RS01625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L6495_RS01700	COG2205	protein histidine kinase activity
L6495_RS01705	COG0745	RESPONSE REGULATOR receiver
L6495_RS01725	COG0697	spore germination
L6495_RS01755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L6495_RS01760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L6495_RS01765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L6495_RS01775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L6495_RS01790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L6495_RS01800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L6495_RS01810	COG0151	Belongs to the GarS family
L6495_RS01835	COG0210	DNA helicase
L6495_RS01845	COG4851	CamS sex pheromone cAM373 precursor
L6495_RS01865	COG1335	isochorismatase
L6495_RS01870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L6495_RS01880	COG1464	Belongs to the NlpA lipoprotein family
L6495_RS01895	COG0003	Pfam Anion-transporting ATPase
L6495_RS01900	COG1846	Transcriptional regulator
L6495_RS01905	COG4682	membrane
L6495_RS01925	COG1597	lipid kinase activity
L6495_RS01930	COG0546	phosphoglycolate phosphatase activity
L6495_RS01935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L6495_RS01945	COG1012	belongs to the aldehyde dehydrogenase family
L6495_RS01950	COG2076	Multidrug Resistance protein
L6495_RS01960	COG2309	aminopeptidase activity
L6495_RS01975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS01980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L6495_RS01985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L6495_RS01995	COG4807	Protein conserved in bacteria
L6495_RS02020	COG1757	Na H antiporter
L6495_RS02025	COG1473	amidohydrolase
L6495_RS02040	COG0450	alkyl hydroperoxide reductase
L6495_RS02060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS02065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS02070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6495_RS02085	COG0166	Belongs to the GPI family
L6495_RS02130	COG3541	Predicted nucleotidyltransferase
L6495_RS02140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6495_RS02140	COG0723	plastoquinol--plastocyanin reductase activity
L6495_RS02165	COG0765	amino acid transport
L6495_RS02170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6495_RS02180	COG0840	transmembrane signaling receptor activity
L6495_RS02185	COG0840	transmembrane signaling receptor activity
L6495_RS02210	COG0366	Alpha amylase catalytic
L6495_RS02215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS02215	COG1263	PTS System
L6495_RS02215	COG2190	(PTS) system
L6495_RS02260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6495_RS02270	COG1116	anion transmembrane transporter activity
L6495_RS02275	COG0488	(ABC) transporter
L6495_RS02325	COG2270	Major facilitator Superfamily
L6495_RS02355	COG2310	stress, protein
L6495_RS02360	COG2310	stress, protein
L6495_RS02365	COG2310	stress, protein
L6495_RS02370	COG0861	Integral membrane protein TerC family
L6495_RS02380	COG3853	Toxic anion resistance protein (TelA)
L6495_RS02395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L6495_RS02405	COG1295	ribonuclease BN
L6495_RS02410	COG2217	Heavy metal translocating P-type atpase
L6495_RS02415	COG0697	spore germination
L6495_RS02425	COG0681	Belongs to the peptidase S26 family
L6495_RS02435	COG0586	Pfam SNARE associated Golgi protein
L6495_RS02450	COG3871	stress protein (general stress protein 26)
L6495_RS02455	COG0387	Pfam Sodium calcium exchanger
L6495_RS02465	COG0535	radical SAM domain protein
L6495_RS02485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L6495_RS02490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L6495_RS02495	COG0101	tRNA pseudouridine synthase activity
L6495_RS02515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6495_RS02545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS02545	COG1263	PTS System
L6495_RS02550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6495_RS02570	COG0463	Glycosyl transferase, family 2
L6495_RS02580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L6495_RS02595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L6495_RS02615	COG1228	amidohydrolase
L6495_RS02620	COG1090	epimerase
L6495_RS02650	COG1988	membrane-bound metal-dependent
L6495_RS02655	COG1194	a g-specific adenine glycosylase
L6495_RS02680	COG1132	(ABC) transporter
L6495_RS02685	COG4129	membrane
L6495_RS02690	COG0067	glutamate synthase
L6495_RS02690	COG0069	glutamate synthase activity
L6495_RS02690	COG0070	glutamate synthase
L6495_RS02700	COG4555	ABC transporter
L6495_RS02720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L6495_RS02725	COG0735	belongs to the Fur family
L6495_RS02870	COG1201	RNA secondary structure unwinding
L6495_RS02945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6495_RS02965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
L6495_RS02970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L6495_RS02980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L6495_RS02990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L6495_RS02995	COG5001	Diguanylate cyclase
L6495_RS02995	COG1716	ATPase activity
L6495_RS03000	COG2766	serine protein kinase
L6495_RS03020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6495_RS03030	COG1585	Membrane protein implicated in regulation of membrane protease activity
L6495_RS03035	COG2268	Band 7 protein
L6495_RS03045	COG3290	protein histidine kinase activity
L6495_RS03050	COG4565	transcriptional regulatory protein
L6495_RS03055	COG2851	Citrate transporter
L6495_RS03075	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L6495_RS03080	COG3842	ATPase activity
L6495_RS03085	COG1175	transmembrane transport
L6495_RS03090	COG0395	ABC-type sugar transport system, permease component
L6495_RS03105	COG0745	RESPONSE REGULATOR receiver
L6495_RS03110	COG5002	protein histidine kinase activity
L6495_RS03130	COG4990	cell redox homeostasis
L6495_RS03140	COG0697	spore germination
L6495_RS03145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS03155	COG5002	protein histidine kinase activity
L6495_RS03160	COG0745	RESPONSE REGULATOR receiver
L6495_RS03165	COG0454	-acetyltransferase
L6495_RS03165	COG0456	acetyltransferase
L6495_RS03170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L6495_RS03175	COG3383	formate dehydrogenase (NAD+) activity
L6495_RS03180	COG2427	Protein of unknown function (DUF1641)
L6495_RS03195	COG0531	amino acid
L6495_RS03200	COG0640	Transcriptional regulator
L6495_RS03205	COG2217	Heavy metal translocating P-type atpase
L6495_RS03210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L6495_RS03225	COG3227	Zinc metalloprotease (Elastase)
L6495_RS03245	COG2720	vancomycin resistance protein
L6495_RS03250	COG1316	TRANSCRIPTIONal
L6495_RS03255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS03260	COG0346	lactoylglutathione lyase activity
L6495_RS03265	COG1253	flavin adenine dinucleotide binding
L6495_RS03270	COG1027	Aspartate ammonia-lyase
L6495_RS03275	COG1620	l-lactate permease
L6495_RS03290	COG3104	oligopeptide transport
L6495_RS03295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6495_RS03300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS03305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS03315	COG2226	methyltransferase
L6495_RS03320	COG0156	8-amino-7-oxononanoate synthase activity
L6495_RS03325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L6495_RS03330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L6495_RS03340	COG4548	von Willebrand factor, type A
L6495_RS03345	COG0714	Associated with various cellular activities
L6495_RS03350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6495_RS03365	COG0531	amino acid
L6495_RS03370	COG2188	Transcriptional regulator
L6495_RS03375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS03375	COG1263	PTS System
L6495_RS03380	COG0366	Alpha amylase catalytic
L6495_RS03395	COG0697	spore germination
L6495_RS03405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6495_RS03410	COG1115	amino acid carrier protein
L6495_RS03415	COG1126	abc transporter atp-binding protein
L6495_RS03420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6495_RS03425	COG0765	amino acid transport
L6495_RS03430	COG0765	amino acid transport
L6495_RS03435	COG0833	amino acid
L6495_RS03460	COG2378	regulation of single-species biofilm formation
L6495_RS03465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L6495_RS03470	COG5002	protein histidine kinase activity
L6495_RS03485	COG0659	secondary active sulfate transmembrane transporter activity
L6495_RS03500	COG4166	transmembrane transport
L6495_RS03510	COG0601	transmembrane transport
L6495_RS03515	COG4608	Belongs to the ABC transporter superfamily
L6495_RS03525	COG2271	Major facilitator Superfamily
L6495_RS03530	COG1846	Transcriptional regulator
L6495_RS03535	COG0477	Major facilitator Superfamily
L6495_RS03540	COG1609	Transcriptional regulator
L6495_RS03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L6495_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
L6495_RS03565	COG1879	ABC-type sugar transport system periplasmic component
L6495_RS03590	COG1063	alcohol dehydrogenase
L6495_RS03605	COG3568	Endonuclease Exonuclease Phosphatase
L6495_RS03635	COG0840	transmembrane signaling receptor activity
L6495_RS03640	COG3584	3D domain protein
L6495_RS03640	COG1388	LysM domain
L6495_RS03645	COG1476	TRANSCRIPTIONal
L6495_RS03660	COG3104	oligopeptide transport
L6495_RS03665	COG1114	Component of the transport system for branched-chain amino acids
L6495_RS03670	COG1464	Belongs to the NlpA lipoprotein family
L6495_RS03675	COG1960	acyl-CoA dehydrogenase activity
L6495_RS03680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L6495_RS03685	COG2011	ABC-type metal ion transport system permease component
L6495_RS03700	COG1113	amino acid transport
L6495_RS03705	COG2252	PERMEase
L6495_RS03720	COG2153	protein acetylation
L6495_RS03730	COG0569	domain protein
L6495_RS03730	COG0475	glutathione-regulated potassium exporter activity
L6495_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L6495_RS03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L6495_RS03755	COG4990	cell redox homeostasis
L6495_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6495_RS03775	COG0697	spore germination
L6495_RS03780	COG0531	amino acid
L6495_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6495_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6495_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6495_RS03800	COG1918	ferrous iron import across plasma membrane
L6495_RS03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L6495_RS03810	COG0573	inorganic phosphate transmembrane transporter activity
L6495_RS03815	COG0581	inorganic phosphate transmembrane transporter activity
L6495_RS03820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L6495_RS03940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
L6495_RS03960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L6495_RS03965	COG1116	anion transmembrane transporter activity
L6495_RS03970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6495_RS03975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6495_RS03980	COG0352	thiamine-phosphate diphosphorylase activity
L6495_RS03985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6495_RS03990	COG2104	thiamine diphosphate biosynthetic process
L6495_RS04000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6495_RS04005	COG0351	phosphomethylpyrimidine kinase
L6495_RS04045	COG2205	protein histidine kinase activity
L6495_RS04050	COG2814	Major facilitator Superfamily
L6495_RS04055	COG1846	Transcriptional regulator
L6495_RS04075	COG1136	(ABC) transporter
L6495_RS04085	COG2252	PERMEase
L6495_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS04110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6495_RS04150	COG0778	Nitroreductase
L6495_RS04155	COG2719	SpoVR family
L6495_RS04165	COG3591	Belongs to the peptidase S1B family
L6495_RS04175	COG0446	pyridine nucleotide-disulphide oxidoreductase
L6495_RS04180	COG1937	Protein conserved in bacteria
L6495_RS04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6495_RS04185	COG0425	Belongs to the sulfur carrier protein TusA family
L6495_RS04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6495_RS04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS04195	COG0425	Belongs to the sulfur carrier protein TusA family
L6495_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6495_RS04210	COG2210	Belongs to the sulfur carrier protein TusA family
L6495_RS04215	COG0730	response to heat
L6495_RS04225	COG1316	TRANSCRIPTIONal
L6495_RS04230	COG0604	alcohol dehydrogenase
L6495_RS04235	COG1283	sodium-dependent phosphate transmembrane transporter activity
L6495_RS04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6495_RS04250	COG3711	transcriptional antiterminator
L6495_RS04255	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6495_RS04260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6495_RS04280	COG1388	LysM domain
L6495_RS04280	COG3584	3D domain protein
L6495_RS04285	COG0577	efflux transmembrane transporter activity
L6495_RS04290	COG1136	(ABC) transporter
L6495_RS04300	COG5522	Integral membrane protein (intg_mem_TP0381)
L6495_RS04315	COG0577	efflux transmembrane transporter activity
L6495_RS04320	COG1114	Component of the transport system for branched-chain amino acids
L6495_RS04325	COG3546	catalase activity
L6495_RS04360	COG0586	Pfam SNARE associated Golgi protein
L6495_RS04395	COG0531	amino acid
L6495_RS04400	COG0475	glutathione-regulated potassium exporter activity
L6495_RS04410	COG1737	Transcriptional regulator
L6495_RS04420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS04420	COG1263	PTS System
L6495_RS04430	COG2259	Doxx family
L6495_RS04445	COG1522	sequence-specific DNA binding
L6495_RS04460	COG2076	Multidrug Resistance protein
L6495_RS04465	COG1309	transcriptional regulator
L6495_RS04470	COG2814	Major facilitator Superfamily
L6495_RS04475	COG0657	acetylesterase activity
L6495_RS04485	COG2124	cytochrome p450
L6495_RS04495	COG1063	alcohol dehydrogenase
L6495_RS04500	COG4533	DNA binding
L6495_RS04505	COG2211	Major facilitator Superfamily
L6495_RS04515	COG0693	protein deglycase activity
L6495_RS04520	COG0753	catalase activity
L6495_RS04530	COG0531	amino acid
L6495_RS04535	COG1012	belongs to the aldehyde dehydrogenase family
L6495_RS04540	COG1132	(ABC) transporter
L6495_RS04545	COG1132	(ABC) transporter
L6495_RS04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6495_RS04555	COG0765	amino acid transport
L6495_RS04560	COG1126	abc transporter atp-binding protein
L6495_RS04575	COG0189	ligase activity
L6495_RS04605	COG0028	Belongs to the TPP enzyme family
L6495_RS04610	COG3527	Alpha-acetolactate decarboxylase
L6495_RS04620	COG0561	phosphatase activity
L6495_RS04625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L6495_RS04640	COG0659	secondary active sulfate transmembrane transporter activity
L6495_RS04660	COG2244	polysaccharide biosynthetic process
L6495_RS04675	COG5263	repeat protein
L6495_RS04675	COG4193	domain, Protein
L6495_RS04690	COG1024	Enoyl-CoA hydratase
L6495_RS04710	COG1363	Peptidase, m42
L6495_RS04840	COG1649	PFAM Uncharacterised BCR, COG1649
L6495_RS04875	COG0601	transmembrane transport
L6495_RS04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6495_RS04885	COG0444	Belongs to the ABC transporter superfamily
L6495_RS04890	COG4608	Belongs to the ABC transporter superfamily
L6495_RS04920	COG0477	Major facilitator Superfamily
L6495_RS04925	COG3290	protein histidine kinase activity
L6495_RS04930	COG4565	transcriptional regulatory protein
L6495_RS04935	COG3181	Tripartite tricarboxylate transporter family receptor
L6495_RS04950	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L6495_RS04985	COG4978	Transcriptional regulator
L6495_RS04985	COG0789	Transcriptional regulator
L6495_RS05030	COG0305	Participates in initiation and elongation during chromosome replication
L6495_RS05080	COG0477	Major facilitator Superfamily
L6495_RS05155	COG1404	Belongs to the peptidase S8 family
L6495_RS05225	COG3711	transcriptional antiterminator
L6495_RS05230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS05230	COG2190	(PTS) system
L6495_RS05230	COG1263	PTS System
L6495_RS05235	COG2723	6-phospho-beta-galactosidase activity
L6495_RS05260	COG0367	asparagine synthase
L6495_RS05275	COG1132	(ABC) transporter
L6495_RS05280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L6495_RS05280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L6495_RS05320	COG1136	(ABC) transporter
L6495_RS05320	COG0577	efflux transmembrane transporter activity
L6495_RS05340	COG1183	phosphatidylcholine synthase activity
L6495_RS05355	COG2376	Dihydroxyacetone kinase
L6495_RS05365	COG2376	Dihydroxyacetone kinase
L6495_RS05460	COG3237	CsbD-like
L6495_RS05485	COG1191	sigma factor activity
L6495_RS05495	COG2208	phosphoserine phosphatase activity
L6495_RS05500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L6495_RS05505	COG0784	Response regulator, receiver
L6495_RS05505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6495_RS05505	COG2198	Histidine kinase
L6495_RS05505	COG2205	protein histidine kinase activity
L6495_RS05545	COG2205	protein histidine kinase activity
L6495_RS05585	COG0420	3'-5' exonuclease activity
L6495_RS05590	COG4717	serine-type aminopeptidase activity
L6495_RS05605	COG0346	lactoylglutathione lyase activity
L6495_RS05610	COG0346	lactoylglutathione lyase activity
L6495_RS05615	COG0457	Tetratricopeptide repeat
L6495_RS05625	COG2267	carboxylic ester hydrolase activity
L6495_RS05655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L6495_RS05660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L6495_RS05670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L6495_RS05715	COG0477	Major facilitator Superfamily
L6495_RS05720	COG0477	Major facilitator Superfamily
L6495_RS05730	COG3973	AAA domain
L6495_RS05735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6495_RS05755	COG4980	gas vesicle protein
L6495_RS05760	COG0537	adenosine 5'-monophosphoramidase activity
L6495_RS05765	COG1131	(ABC) transporter
L6495_RS05770	COG4473	ABC transporter
L6495_RS05785	COG1309	transcriptional regulator
L6495_RS05795	COG3402	PFAM membrane-flanked domain
L6495_RS05800	COG3428	Bacterial PH domain
L6495_RS05830	COG3402	PFAM membrane-flanked domain
L6495_RS05835	COG3428	Bacterial PH domain
L6495_RS05840	COG2329	Antibiotic biosynthesis monooxygenase
L6495_RS05845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6495_RS05860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L6495_RS05885	COG1309	transcriptional regulator
L6495_RS05890	COG1511	domain protein
L6495_RS05920	COG2378	regulation of single-species biofilm formation
L6495_RS05925	COG1609	Transcriptional regulator
L6495_RS05935	COG1234	tRNA 3'-trailer cleavage
L6495_RS05940	COG0095	Lipoate-protein ligase
L6495_RS05950	COG2205	protein histidine kinase activity
L6495_RS05955	COG0745	RESPONSE REGULATOR receiver
L6495_RS05980	COG0501	Belongs to the peptidase M48B family
L6495_RS05985	COG0697	spore germination
L6495_RS06005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L6495_RS06010	COG2224	Isocitrate lyase
L6495_RS06020	COG1278	Cold shock
L6495_RS06035	COG4903	ComK protein
L6495_RS06045	COG4585	Histidine kinase
L6495_RS06050	COG2197	response regulator
L6495_RS06060	COG0398	Pfam SNARE associated Golgi protein
L6495_RS06135	COG0179	Fumarylacetoacetate (FAA) hydrolase
L6495_RS06160	COG0367	asparagine synthase
L6495_RS06165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L6495_RS06170	COG0753	catalase activity
L6495_RS06180	COG0004	ammonium transporteR
L6495_RS06200	COG2996	Protein conserved in bacteria
L6495_RS06205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6495_RS06215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS06230	COG0561	phosphatase activity
L6495_RS06240	COG0542	response to heat
L6495_RS06250	COG2267	carboxylic ester hydrolase activity
L6495_RS06265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6495_RS06270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L6495_RS06275	COG5504	Zn-dependent protease
L6495_RS06285	COG0180	Tryptophanyl-tRNA synthetase
L6495_RS06295	COG4166	transmembrane transport
L6495_RS06300	COG0601	transmembrane transport
L6495_RS06305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6495_RS06310	COG0444	Belongs to the ABC transporter superfamily
L6495_RS06315	COG4608	Belongs to the ABC transporter superfamily
L6495_RS06320	COG0534	Mate efflux family protein
L6495_RS06325	COG4166	transmembrane transport
L6495_RS06340	COG0861	Integral membrane protein TerC family
L6495_RS06345	COG4862	establishment of competence for transformation
L6495_RS06350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6495_RS06360	COG1164	Oligoendopeptidase f
L6495_RS06375	COG2346	COG2346, Truncated hemoglobins
L6495_RS06380	COG4116	CYTH
L6495_RS06390	COG2357	RelA SpoT domain protein
L6495_RS06400	COG0564	pseudouridine synthase activity
L6495_RS06415	COG0772	Belongs to the SEDS family
L6495_RS06420	COG1216	Glycosyl transferase, family 2
L6495_RS06440	COG0457	Tetratricopeptide repeat
L6495_RS06440	COG0463	Glycosyl transferase, family 2
L6495_RS06460	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L6495_RS06475	COG1091	dTDP-4-dehydrorhamnose reductase activity
L6495_RS06520	COG2153	protein acetylation
L6495_RS06530	COG2382	esterase
L6495_RS06545	COG5492	domain, Protein
L6495_RS06550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6495_RS06560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L6495_RS06560	COG0512	Glutamine amidotransferase of anthranilate synthase
L6495_RS06595	COG1620	l-lactate permease
L6495_RS06600	COG5634	Uncharacterized conserved protein (DUF2278)
L6495_RS06665	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6495_RS06675	COG1476	TRANSCRIPTIONal
L6495_RS06720	COG2226	methyltransferase
L6495_RS06730	COG1686	Belongs to the peptidase S11 family
L6495_RS06735	COG0681	Belongs to the peptidase S26 family
L6495_RS06755	COG1396	sequence-specific DNA binding
L6495_RS06770	COG1012	belongs to the aldehyde dehydrogenase family
L6495_RS06780	COG1176	ABC-type spermidine putrescine transport system, permease component I
L6495_RS06785	COG1177	transmembrane transport
L6495_RS06790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
L6495_RS06800	COG2409	Drug exporters of the RND superfamily
L6495_RS06810	COG0564	pseudouridine synthase activity
L6495_RS06820	COG2340	Cysteine-rich secretory protein family
L6495_RS06825	COG0247	lactate metabolic process
L6495_RS06830	COG0277	FAD linked oxidase domain protein
L6495_RS06835	COG3835	regulator
L6495_RS06845	COG0745	RESPONSE REGULATOR receiver
L6495_RS06850	COG5002	protein histidine kinase activity
L6495_RS06855	COG2186	Transcriptional regulator
L6495_RS06875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L6495_RS06885	COG2116	formate transmembrane transporter activity
L6495_RS06890	COG0861	Integral membrane protein TerC family
L6495_RS06895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6495_RS06905	COG2030	dehydratase
L6495_RS06925	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS06930	COG3243	poly(R)-hydroxyalkanoic acid synthase
L6495_RS06935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6495_RS06940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6495_RS06960	COG1840	ABC-type Fe3 transport system, periplasmic component
L6495_RS06965	COG3842	ATPase activity
L6495_RS06990	COG1349	DNA-binding transcription factor activity
L6495_RS07000	COG0235	Class ii aldolase
L6495_RS07010	COG2861	carbohydrate metabolic process
L6495_RS07020	COG3852	Histidine kinase
L6495_RS07035	COG2318	DinB family
L6495_RS07045	COG5002	protein histidine kinase activity
L6495_RS07055	COG0720	synthase
L6495_RS07070	COG4873	Protein conserved in bacteria
L6495_RS07100	COG1780	Probably involved in ribonucleotide reductase function
L6495_RS07110	COG1403	HNH endonuclease
L6495_RS07120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L6495_RS07125	COG1725	Transcriptional regulator
L6495_RS07130	COG1131	(ABC) transporter
L6495_RS07140	COG1131	(ABC) transporter
L6495_RS07145	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6495_RS07160	COG1522	sequence-specific DNA binding
L6495_RS07170	COG1335	isochorismatase
L6495_RS07180	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6495_RS07185	COG2070	2-Nitropropane dioxygenase
L6495_RS07190	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L6495_RS07200	COG1696	Membrane protein involved in D-alanine export
L6495_RS07225	COG0716	FMN binding
L6495_RS07240	COG3173	Aminoglycoside phosphotransferase
L6495_RS07260	COG0534	Mate efflux family protein
L6495_RS07265	COG1968	undecaprenyl-diphosphatase activity
L6495_RS07280	COG1846	Transcriptional regulator
L6495_RS07290	COG1301	dicarboxylic acid transport
L6495_RS07295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6495_RS07300	COG4709	membrane
L6495_RS07305	COG3874	Sporulation protein YtfJ
L6495_RS07325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6495_RS07330	COG0028	Belongs to the TPP enzyme family
L6495_RS07335	COG0440	acetolactate synthase activity
L6495_RS07410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L6495_RS07425	COG1183	phosphatidylcholine synthase activity
L6495_RS07430	COG1368	sulfuric ester hydrolase activity
L6495_RS07440	COG0019	diaminopimelate decarboxylase activity
L6495_RS07460	COG0529	Catalyzes the synthesis of activated sulfate
L6495_RS07465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L6495_RS07485	COG1648	precorrin-2 dehydrogenase activity
L6495_RS07490	COG0733	neurotransmitter:sodium symporter activity
L6495_RS07510	COG1757	Na H antiporter
L6495_RS07525	COG4758	membrane
L6495_RS07530	COG4585	Histidine kinase
L6495_RS07535	COG2197	response regulator
L6495_RS07545	COG1114	Component of the transport system for branched-chain amino acids
L6495_RS07555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L6495_RS07595	COG0730	response to heat
L6495_RS07600	COG0306	phosphate transporter
L6495_RS07605	COG1392	Phosphate transport regulator
L6495_RS07610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6495_RS07625	COG3852	Histidine kinase
L6495_RS07630	COG1801	Protein of unknown function DUF72
L6495_RS07645	COG0582	viral genome integration into host DNA
L6495_RS07670	COG0392	lysyltransferase activity
L6495_RS07670	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L6495_RS07685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6495_RS07690	COG1686	Belongs to the peptidase S11 family
L6495_RS07695	COG2715	membrane protein required for spore maturation
L6495_RS07700	COG0700	Nucleoside recognition
L6495_RS07705	COG1187	pseudouridine synthase activity
L6495_RS07715	COG1333	cytochrome c biogenesis protein
L6495_RS07720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L6495_RS07725	COG0745	RESPONSE REGULATOR receiver
L6495_RS07730	COG5002	protein histidine kinase activity
L6495_RS07735	COG2096	Adenosyltransferase
L6495_RS07740	COG4942	peptidase
L6495_RS07750	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L6495_RS07755	COG1141	Ferredoxin
L6495_RS07765	COG0514	ATP-dependent DNA helicase (RecQ)
L6495_RS07770	COG1266	CAAX protease self-immunity
L6495_RS07780	COG1408	metallophosphoesterase
L6495_RS07790	COG4862	establishment of competence for transformation
L6495_RS07795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L6495_RS07815	COG0492	ferredoxin-NADP+ reductase activity
L6495_RS07820	COG0252	asparaginase activity
L6495_RS07890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6495_RS07905	COG0142	geranyltranstransferase activity
L6495_RS07915	COG0142	geranyltranstransferase activity
L6495_RS07940	COG0457	Tetratricopeptide repeat
L6495_RS07960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L6495_RS07970	COG4347	Protein of unknown function (DUF1405)
L6495_RS07985	COG2738	Putative neutral zinc metallopeptidase
L6495_RS07995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS08000	COG1694	Mazg nucleotide pyrophosphohydrolase
L6495_RS08015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L6495_RS08020	COG0438	transferase activity, transferring glycosyl groups
L6495_RS08055	COG1199	ATP-dependent helicase activity
L6495_RS08055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L6495_RS08075	COG3935	DnaD domain protein
L6495_RS08080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L6495_RS08090	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6495_RS08090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6495_RS08150	COG0116	Belongs to the methyltransferase superfamily
L6495_RS08160	COG1199	ATP-dependent helicase activity
L6495_RS08165	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L6495_RS08175	COG3173	Aminoglycoside phosphotransferase
L6495_RS08180	COG0024	Methionine aminopeptidase
L6495_RS08190	COG2233	PERMEase
L6495_RS08195	COG2311	Membrane
L6495_RS08200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6495_RS08210	COG0456	acetyltransferase
L6495_RS08250	COG0754	glutathionylspermidine amidase activity
L6495_RS08265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6495_RS08280	COG0454	-acetyltransferase
L6495_RS08300	COG0328	RNA-DNA hybrid ribonuclease activity
L6495_RS08335	COG3403	YqcI/YcgG family
L6495_RS08340	COG1280	lysine exporter protein (LysE YggA)
L6495_RS08355	COG3162	membrane
L6495_RS08360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6495_RS08365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6495_RS08375	COG0475	glutathione-regulated potassium exporter activity
L6495_RS08380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6495_RS08385	COG0789	Transcriptional regulator
L6495_RS08385	COG4978	Transcriptional regulator
L6495_RS08395	COG2323	membrane
L6495_RS08400	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L6495_RS08435	COG2814	Major facilitator Superfamily
L6495_RS08465	COG1923	regulation of RNA biosynthetic process
L6495_RS08475	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L6495_RS08480	COG1360	Flagellar Motor Protein
L6495_RS08485	COG2201	protein-glutamate methylesterase activity
L6495_RS08490	COG2198	Histidine kinase
L6495_RS08490	COG0643	Histidine kinase
L6495_RS08495	COG1776	CheC inhibitor of MCP methylation
L6495_RS08495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6495_RS08510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L6495_RS08530	COG1256	bacterial-type flagellum assembly
L6495_RS08535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L6495_RS08540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
L6495_RS08555	COG1815	bacterial-type flagellum-dependent cell motility
L6495_RS08560	COG1558	bacterial-type flagellum-dependent cell motility
L6495_RS08570	COG1766	The M ring may be actively involved in energy transduction
L6495_RS08575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6495_RS08585	COG1157	protein secretion by the type III secretion system
L6495_RS08620	COG0784	Response regulator, receiver
L6495_RS08620	COG0835	chemotaxis
L6495_RS08630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L6495_RS08640	COG0741	lytic transglycosylase activity
L6495_RS08650	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6495_RS08655	COG1776	CheC inhibitor of MCP methylation
L6495_RS08655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6495_RS08665	COG1338	Plays a role in the flagellum-specific transport system
L6495_RS08670	COG1987	bacterial-type flagellum assembly
L6495_RS08685	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L6495_RS08690	COG1419	protein localization to endoplasmic reticulum
L6495_RS08695	COG4786	Flagellar basal body rod
L6495_RS08700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L6495_RS08725	COG1309	transcriptional regulator
L6495_RS08745	COG2329	Antibiotic biosynthesis monooxygenase
L6495_RS08760	COG3764	Sortase (surface protein transpeptidase)
L6495_RS08765	COG3764	Sortase (surface protein transpeptidase)
L6495_RS08790	COG0583	DNA-binding transcription factor activity
L6495_RS08795	COG3842	ATPase activity
L6495_RS08800	COG0725	ABC transporter, periplasmic molybdate-binding protein
L6495_RS08810	COG1234	tRNA 3'-trailer cleavage
L6495_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS08860	COG1846	Transcriptional regulator
L6495_RS08870	COG0367	asparagine synthase
L6495_RS08900	COG1802	Transcriptional regulator
L6495_RS08905	COG0697	spore germination
L6495_RS08910	COG0523	cobalamin synthesis protein
L6495_RS08915	COG0701	Predicted permease
L6495_RS08930	COG1757	Na H antiporter
L6495_RS08935	COG0114	fumarate hydratase activity
L6495_RS08950	COG0534	Mate efflux family protein
L6495_RS08955	COG3340	Belongs to the peptidase S51 family
L6495_RS08975	COG0785	Cytochrome C biogenesis protein
L6495_RS09010	COG2733	membrane
L6495_RS09045	COG1131	(ABC) transporter
L6495_RS09060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6495_RS09085	COG0528	UMP kinase activity
L6495_RS09095	COG1027	Aspartate ammonia-lyase
L6495_RS09100	COG0281	malic enzyme
L6495_RS09105	COG4191	Histidine kinase
L6495_RS09110	COG0784	Response regulator, receiver
L6495_RS09120	COG1361	Conserved repeat domain
L6495_RS09230	COG2814	Major facilitator Superfamily
L6495_RS09245	COG1966	Carbon starvation protein
L6495_RS09255	COG1695	Transcriptional regulator
L6495_RS09265	COG0477	Major facilitator Superfamily
L6495_RS09270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6495_RS09275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L6495_RS09280	COG4166	transmembrane transport
L6495_RS09285	COG2223	nitrite transmembrane transporter activity
L6495_RS09290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6495_RS09305	COG2244	polysaccharide biosynthetic process
L6495_RS09310	COG0733	neurotransmitter:sodium symporter activity
L6495_RS09320	COG5566	PFAM Mor transcription activator
L6495_RS09325	COG2323	membrane
L6495_RS09340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6495_RS09350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6495_RS09355	COG0028	Belongs to the TPP enzyme family
L6495_RS09365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
L6495_RS09375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L6495_RS09400	COG2814	Major facilitator Superfamily
L6495_RS09405	COG3384	dioxygenase
L6495_RS09415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L6495_RS09425	COG0427	acetyl-CoA hydrolase
L6495_RS09445	COG1073	alpha beta
L6495_RS09450	COG4166	transmembrane transport
L6495_RS09475	COG0535	radical SAM domain protein
L6495_RS09480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS09505	COG1914	H( )-stimulated, divalent metal cation uptake system
L6495_RS09520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L6495_RS09525	COG0531	amino acid
L6495_RS09560	COG0714	Associated with various cellular activities
L6495_RS09570	COG3552	Protein containing von Willebrand factor type A (VWA) domain
L6495_RS09595	COG2390	Transcriptional regulator
L6495_RS09605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS09610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L6495_RS09640	COG0006	proline dipeptidase activity
L6495_RS09645	COG2132	Multicopper oxidase
L6495_RS09660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L6495_RS09690	COG1114	Component of the transport system for branched-chain amino acids
L6495_RS09700	COG1276	copper resistance
L6495_RS09700	COG2372	response to copper ion
L6495_RS09705	COG4549	nuclear export factor GLE1
L6495_RS09715	COG0697	spore germination
L6495_RS09720	COG0583	DNA-binding transcription factor activity
L6495_RS09725	COG1959	2 iron, 2 sulfur cluster binding
L6495_RS09730	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L6495_RS09735	COG0778	Nitroreductase
L6495_RS09745	COG0628	permease
L6495_RS09755	COG1231	oxidoreductase activity
L6495_RS09760	COG0523	cobalamin synthesis protein
L6495_RS09770	COG0318	PFAM AMP-dependent synthetase and ligase
L6495_RS09775	COG2030	dehydratase
L6495_RS09780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6495_RS09790	COG0411	ABC transporter
L6495_RS09810	COG0583	DNA-binding transcription factor activity
L6495_RS09840	COG1271	oxidase subunit
L6495_RS09845	COG1294	oxidase, subunit
L6495_RS09850	COG4988	ABC transporter
L6495_RS09855	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L6495_RS09875	COG1686	Belongs to the peptidase S11 family
L6495_RS09890	COG0791	NLP P60 protein
L6495_RS09890	COG1388	LysM domain
L6495_RS09900	COG1132	(ABC) transporter
L6495_RS09905	COG0745	RESPONSE REGULATOR receiver
L6495_RS09910	COG5002	protein histidine kinase activity
L6495_RS09915	COG2205	protein histidine kinase activity
L6495_RS09920	COG0745	RESPONSE REGULATOR receiver
L6495_RS09945	COG0300	oxidoreductase activity
L6495_RS09950	COG4122	O-methyltransferase activity
L6495_RS09965	COG5658	integral membrane protein
L6495_RS09980	COG0460	homoserine dehydrogenase
L6495_RS10005	COG1316	TRANSCRIPTIONal
L6495_RS10015	COG0745	RESPONSE REGULATOR receiver
L6495_RS10020	COG5002	protein histidine kinase activity
L6495_RS10035	COG1285	pathogenesis
L6495_RS10040	COG1247	-acetyltransferase
L6495_RS10060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6495_RS10070	COG1082	Xylose isomerase domain protein TIM barrel
L6495_RS10080	COG2814	Major facilitator Superfamily
L6495_RS10085	COG1279	arginine transmembrane transporter activity
L6495_RS10095	COG1752	Esterase of the alpha-beta hydrolase superfamily
L6495_RS10130	COG0577	efflux transmembrane transporter activity
L6495_RS10135	COG2002	toxin-antitoxin pair type II binding
L6495_RS10140	COG1404	Belongs to the peptidase S8 family
L6495_RS10145	COG0640	Transcriptional regulator
L6495_RS10150	COG0667	Aldo Keto reductase
L6495_RS10155	COG2814	Major facilitator Superfamily
L6495_RS10180	COG0840	transmembrane signaling receptor activity
L6495_RS10195	COG3949	Membrane
L6495_RS10200	COG0783	Belongs to the Dps family
L6495_RS10215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6495_RS10225	COG1231	oxidoreductase activity
L6495_RS10235	COG4989	oxidoreductase activity
L6495_RS10240	COG0523	cobalamin synthesis protein
L6495_RS10245	COG0456	acetyltransferase
L6495_RS10250	COG0803	Belongs to the bacterial solute-binding protein 9 family
L6495_RS10250	COG3443	Belongs to the bacterial solute-binding protein 9 family
L6495_RS10260	COG0702	epimerase
L6495_RS10270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L6495_RS10280	COG4166	transmembrane transport
L6495_RS10295	COG0406	alpha-ribazole phosphatase activity
L6495_RS10305	COG5337	Spore coat protein CotH
L6495_RS10310	COG1051	belongs to the nudix hydrolase family
L6495_RS10315	COG0586	Pfam SNARE associated Golgi protein
L6495_RS10320	COG2244	polysaccharide biosynthetic process
L6495_RS10330	COG0701	Predicted permease
L6495_RS10335	COG3689	TIGRFAM TIGR03943 family protein
L6495_RS10340	COG1607	acyl-coa hydrolase
L6495_RS10350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6495_RS10365	COG0702	epimerase
L6495_RS10370	COG2839	Protein conserved in bacteria
L6495_RS10375	COG1253	flavin adenine dinucleotide binding
L6495_RS10390	COG1114	Component of the transport system for branched-chain amino acids
L6495_RS10395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6495_RS10415	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6495_RS10425	COG1876	peptidase activity
L6495_RS10435	COG0154	amidase activity
L6495_RS10440	COG2211	Major facilitator Superfamily
L6495_RS10455	COG2368	4-hydroxyphenylacetate
L6495_RS10465	COG0196	riboflavin kinase activity
L6495_RS10480	COG0251	oxidation-reduction process
L6495_RS10490	COG3971	2-oxopent-4-enoate hydratase activity
L6495_RS10510	COG1942	4-Oxalocrotonate Tautomerase
L6495_RS10530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L6495_RS10535	COG4106	trans-aconitate 2-methyltransferase activity
L6495_RS10550	COG1819	glycosyl
L6495_RS10555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS10560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS10590	COG0456	acetyltransferase
L6495_RS10630	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6495_RS10730	COG3874	Sporulation protein YtfJ
L6495_RS10755	COG2226	methyltransferase
L6495_RS10780	COG0346	lactoylglutathione lyase activity
L6495_RS10790	COG0604	alcohol dehydrogenase
L6495_RS10795	COG1595	DNA-templated transcription, initiation
L6495_RS10825	COG0386	Belongs to the glutathione peroxidase family
L6495_RS10835	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L6495_RS10840	COG0714	Associated with various cellular activities
L6495_RS10855	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
L6495_RS10860	COG1140	nitrate reductase beta subunit
L6495_RS10865	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L6495_RS10870	COG2181	nitrate reductase activity
L6495_RS10875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L6495_RS10880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L6495_RS10885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6495_RS10890	COG0303	'Molybdopterin
L6495_RS10895	COG0314	molybdopterin synthase activity
L6495_RS10915	COG1648	precorrin-2 dehydrogenase activity
L6495_RS10925	COG1587	Uroporphyrinogen-III synthase
L6495_RS10925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L6495_RS10930	COG2146	nitrite reductase [NAD(P)H] activity
L6495_RS10935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L6495_RS10940	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L6495_RS10975	COG2359	stage V sporulation protein S
L6495_RS11000	COG1418	mRNA catabolic process
L6495_RS11005	COG0488	(ABC) transporter
L6495_RS11020	COG0629	single-stranded DNA binding
L6495_RS11035	COG1413	lyase activity
L6495_RS11050	COG2136	Putative SAM-dependent methyltransferase
L6495_RS11050	COG2521	methyltransferase
L6495_RS11100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L6495_RS11105	COG0017	Asparaginyl-tRNA synthetase
L6495_RS11110	COG1929	Belongs to the glycerate kinase type-1 family
L6495_RS11115	COG0471	metal ion transport
L6495_RS11120	COG0745	RESPONSE REGULATOR receiver
L6495_RS11125	COG3850	Histidine kinase
L6495_RS11125	COG5002	protein histidine kinase activity
L6495_RS11165	COG2610	gluconate transmembrane transporter activity
L6495_RS11170	COG1454	alcohol dehydrogenase
L6495_RS11175	COG1794	racemase activity, acting on amino acids and derivatives
L6495_RS11185	COG0456	acetyltransferase
L6495_RS11190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L6495_RS11200	COG1131	(ABC) transporter
L6495_RS11205	COG4473	ABC transporter
L6495_RS11215	COG0546	phosphoglycolate phosphatase activity
L6495_RS11235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6495_RS11240	COG3250	beta-galactosidase activity
L6495_RS11255	COG0768	penicillin binding
L6495_RS11265	COG0204	Acyl-transferase
L6495_RS11270	COG1272	protein, Hemolysin III
L6495_RS11280	COG0805	protein transport
L6495_RS11290	COG1307	EDD domain protein, DegV family
L6495_RS11300	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L6495_RS11305	COG1999	signal sequence binding
L6495_RS11310	COG0071	Belongs to the small heat shock protein (HSP20) family
L6495_RS11315	COG0367	asparagine synthase
L6495_RS11335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6495_RS11340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6495_RS11360	COG1335	isochorismatase
L6495_RS11365	COG0071	Belongs to the small heat shock protein (HSP20) family
L6495_RS11370	COG0668	transmembrane transport
L6495_RS11375	COG4585	Histidine kinase
L6495_RS11375	COG2203	Gaf domain
L6495_RS11380	COG2197	response regulator
L6495_RS11390	COG1064	alcohol dehydrogenase
L6495_RS11445	COG1125	glycine betaine transport
L6495_RS11445	COG0517	IMP dehydrogenase activity
L6495_RS11450	COG1174	glycine betaine transport
L6495_RS11490	COG1253	flavin adenine dinucleotide binding
L6495_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
L6495_RS11500	COG5506	Protein of unknown function (DUF1694)
L6495_RS11515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6495_RS11520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L6495_RS11525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L6495_RS11530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6495_RS11535	COG0456	acetyltransferase
L6495_RS11540	COG3829	transcription factor binding
L6495_RS11545	COG1509	lysine 2,3-aminomutase activity
L6495_RS11580	COG4991	sh3 domain protein
L6495_RS11580	COG0515	serine threonine protein kinase
L6495_RS11580	COG3064	Membrane
L6495_RS11590	COG0671	phosphoesterase, PA-phosphatase related
L6495_RS11615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6495_RS11615	COG0456	acetyltransferase
L6495_RS11630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L6495_RS11635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6495_RS11685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6495_RS11715	COG0300	oxidoreductase activity
L6495_RS11735	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6495_RS11735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6495_RS11750	COG4841	protein insertion into membrane
L6495_RS11755	COG0372	Belongs to the citrate synthase family
L6495_RS11760	COG2079	MmgE PrpD family protein
L6495_RS11765	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L6495_RS11770	COG1960	acyl-CoA dehydrogenase activity
L6495_RS11785	COG1280	lysine exporter protein (LysE YggA)
L6495_RS11790	COG1024	Enoyl-CoA hydratase
L6495_RS11805	COG0420	3'-5' exonuclease activity
L6495_RS11830	COG2223	nitrite transmembrane transporter activity
L6495_RS11835	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS11840	COG1169	isochorismate synthase
L6495_RS11845	COG1021	2,3-dihydroxybenzoate-AMP ligase
L6495_RS11850	COG1535	isochorismatase
L6495_RS11850	COG3433	isochorismatase activity
L6495_RS11855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L6495_RS11860	COG3251	PFAM MbtH domain protein
L6495_RS11865	COG2814	Major facilitator Superfamily
L6495_RS11880	COG0776	regulation of translation
L6495_RS11890	COG2318	DinB family
L6495_RS11900	COG1115	amino acid carrier protein
L6495_RS11915	COG2329	Antibiotic biosynthesis monooxygenase
L6495_RS11920	COG1187	pseudouridine synthase activity
L6495_RS11925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L6495_RS11930	COG1136	(ABC) transporter
L6495_RS11945	COG2814	Major facilitator Superfamily
L6495_RS12005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS12040	COG1247	-acetyltransferase
L6495_RS12070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L6495_RS12080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS12090	COG1278	Cold shock
L6495_RS12105	COG0010	Belongs to the arginase family
L6495_RS12115	COG1846	Transcriptional regulator
L6495_RS12120	COG2814	Major facilitator Superfamily
L6495_RS12125	COG0583	DNA-binding transcription factor activity
L6495_RS12130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L6495_RS12145	COG0583	DNA-binding transcription factor activity
L6495_RS12150	COG2258	MOSC domain
L6495_RS12165	COG1132	(ABC) transporter
L6495_RS12170	COG1132	(ABC) transporter
L6495_RS12190	COG1396	sequence-specific DNA binding
L6495_RS12220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L6495_RS12230	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
L6495_RS12235	COG1595	DNA-templated transcription, initiation
L6495_RS12260	COG1649	PFAM Uncharacterised BCR, COG1649
L6495_RS12285	COG2971	BadF BadG BcrA BcrD
L6495_RS12295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L6495_RS12345	COG1309	transcriptional regulator
L6495_RS12360	COG1136	(ABC) transporter
L6495_RS12360	COG0577	efflux transmembrane transporter activity
L6495_RS12410	COG1846	Transcriptional regulator
L6495_RS12440	COG2195	Cleaves the N-terminal amino acid of tripeptides
L6495_RS12450	COG0110	maltose O-acetyltransferase activity
L6495_RS12455	COG1686	Belongs to the peptidase S11 family
L6495_RS12465	COG0768	penicillin binding
L6495_RS12470	COG1595	DNA-templated transcription, initiation
L6495_RS12480	COG0768	penicillin binding
L6495_RS12485	COG0768	penicillin binding
L6495_RS12490	COG2367	Beta-lactamase
L6495_RS12505	COG1131	(ABC) transporter
L6495_RS12515	COG1309	transcriptional regulator
L6495_RS12530	COG1960	acyl-CoA dehydrogenase activity
L6495_RS12535	COG0439	Biotin carboxylase
L6495_RS12540	COG0511	ligase activity, forming carbon-carbon bonds
L6495_RS12545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L6495_RS12550	COG1024	Enoyl-CoA hydratase
L6495_RS12555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L6495_RS12560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6495_RS12570	COG1247	-acetyltransferase
L6495_RS12575	COG0572	uridine kinase
L6495_RS12610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L6495_RS12630	COG3227	Zinc metalloprotease (Elastase)
L6495_RS12645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L6495_RS12675	COG2814	Major facilitator Superfamily
L6495_RS12685	COG2226	methyltransferase
L6495_RS12720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS12765	COG3386	PFAM SMP-30 Gluconolaconase
L6495_RS12775	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L6495_RS12780	COG3773	Cell wall hydrolase
L6495_RS12790	COG0745	RESPONSE REGULATOR receiver
L6495_RS12795	COG2205	protein histidine kinase activity
L6495_RS12805	COG0488	(ABC) transporter
L6495_RS12815	COG1136	(ABC) transporter
L6495_RS12820	COG0577	efflux transmembrane transporter activity
L6495_RS12845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS12855	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L6495_RS12970	COG2124	cytochrome p450
L6495_RS13005	COG0561	phosphatase activity
L6495_RS13020	COG1819	glycosyl
L6495_RS13025	COG1794	racemase activity, acting on amino acids and derivatives
L6495_RS13060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6495_RS13065	COG0604	alcohol dehydrogenase
L6495_RS13070	COG0671	phosphoesterase, PA-phosphatase related
L6495_RS13075	COG0768	penicillin binding
L6495_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS13095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6495_RS13135	COG0693	protein deglycase activity
L6495_RS13160	COG2814	Major facilitator Superfamily
L6495_RS13175	COG0584	glycerophosphoryl diester phosphodiesterase
L6495_RS13195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS13200	COG0697	spore germination
L6495_RS13220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6495_RS13230	COG2223	nitrite transmembrane transporter activity
L6495_RS13245	COG2816	NAD+ diphosphatase activity
L6495_RS13250	COG0592	DNA-directed DNA polymerase activity
L6495_RS13255	COG1051	belongs to the nudix hydrolase family
L6495_RS13285	COG3878	Protein conserved in bacteria
L6495_RS13310	COG4667	esterase of the alpha-beta hydrolase superfamily
L6495_RS13335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L6495_RS13350	COG0322	excinuclease ABC activity
L6495_RS13395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6495_RS13420	COG1011	Hydrolase
L6495_RS13440	COG1523	belongs to the glycosyl hydrolase 13 family
L6495_RS13445	COG3227	Zinc metalloprotease (Elastase)
L6495_RS13465	COG0201	protein transport
L6495_RS13475	COG0697	spore germination
L6495_RS13480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS13515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS13530	COG2959	enzyme of heme biosynthesis
L6495_RS13560	COG3844	kynureninase activity
L6495_RS13565	COG1309	transcriptional regulator
L6495_RS13595	COG3284	Transcriptional regulator
L6495_RS13615	COG1349	DNA-binding transcription factor activity
L6495_RS13625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L6495_RS13630	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6495_RS13635	COG0022	dehydrogenase e1 component
L6495_RS13640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6495_RS13650	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS13665	COG1051	belongs to the nudix hydrolase family
L6495_RS13685	COG4176	ABC-type proline glycine betaine transport system permease component
L6495_RS13690	COG0517	IMP dehydrogenase activity
L6495_RS13690	COG4175	Glycine betaine
L6495_RS13715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
L6495_RS13720	COG2153	protein acetylation
L6495_RS13725	COG3397	chitin binding
L6495_RS13740	COG2205	protein histidine kinase activity
L6495_RS13745	COG2226	methyltransferase
L6495_RS13750	COG2315	Protein conserved in bacteria
L6495_RS13755	COG2153	protein acetylation
L6495_RS13810	COG3973	AAA domain
L6495_RS13830	COG0514	ATP-dependent DNA helicase (RecQ)
L6495_RS13850	COG4637	Psort location Cytoplasmic, score
L6495_RS13875	COG3397	chitin binding
L6495_RS13890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L6495_RS13895	COG1115	amino acid carrier protein
L6495_RS13900	COG1012	belongs to the aldehyde dehydrogenase family
L6495_RS13905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L6495_RS13915	COG3938	Belongs to the proline racemase family
L6495_RS13920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6495_RS13960	COG0586	Pfam SNARE associated Golgi protein
L6495_RS13975	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L6495_RS13980	COG0519	Catalyzes the synthesis of GMP from XMP
L6495_RS13985	COG4166	transmembrane transport
L6495_RS13995	COG4948	Mandelate Racemase Muconate Lactonizing
L6495_RS14035	COG2936	dipeptidyl-peptidase activity
L6495_RS14040	COG5002	protein histidine kinase activity
L6495_RS14045	COG0745	RESPONSE REGULATOR receiver
L6495_RS14080	COG1164	Oligoendopeptidase f
L6495_RS14085	COG0531	amino acid
L6495_RS14090	COG1522	sequence-specific DNA binding
L6495_RS14095	COG1307	EDD domain protein, DegV family
L6495_RS14135	COG2814	Major facilitator Superfamily
L6495_RS14145	COG1664	Polymer-forming cytoskeletal
L6495_RS14150	COG0789	Transcriptional regulator
L6495_RS14155	COG4533	DNA binding
L6495_RS14160	COG2814	Major facilitator Superfamily
L6495_RS14160	COG0477	Major facilitator Superfamily
L6495_RS14180	COG2261	transglycosylase associated protein
L6495_RS14230	COG0436	Aminotransferase
L6495_RS14235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L6495_RS14240	COG5146	pantothenate kinase activity
L6495_RS14245	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
L6495_RS14260	COG1131	(ABC) transporter
L6495_RS14310	COG0628	permease
L6495_RS14325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6495_RS14330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6495_RS14335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6495_RS14350	COG2816	NAD+ diphosphatase activity
L6495_RS14370	COG2746	aminoglycoside 3-N-acetyltransferase activity
L6495_RS14395	COG0697	spore germination
L6495_RS14400	COG2318	DinB family
L6495_RS14405	COG0454	-acetyltransferase
L6495_RS14420	COG4912	Dna alkylation repair
L6495_RS14440	COG0861	Integral membrane protein TerC family
L6495_RS14445	COG1368	sulfuric ester hydrolase activity
L6495_RS14450	COG0488	(ABC) transporter
L6495_RS14460	COG1033	growth of symbiont in host cell
L6495_RS14460	COG2409	Drug exporters of the RND superfamily
L6495_RS14465	COG1309	transcriptional regulator
L6495_RS14485	COG0287	Prephenate dehydrogenase
L6495_RS14490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L6495_RS14500	COG1605	Chorismate mutase
L6495_RS14500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L6495_RS14535	COG1388	LysM domain
L6495_RS14535	COG3584	3D domain protein
L6495_RS14545	COG1595	DNA-templated transcription, initiation
L6495_RS14570	COG1879	ABC-type sugar transport system periplasmic component
L6495_RS14580	COG1172	Belongs to the binding-protein-dependent transport system permease family
L6495_RS14635	COG2390	Transcriptional regulator
L6495_RS14640	COG1070	Carbohydrate kinase
L6495_RS14670	COG2329	Antibiotic biosynthesis monooxygenase
L6495_RS14690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS14705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6495_RS14710	COG4187	Peptidase family M20/M25/M40
L6495_RS14715	COG1414	Transcriptional regulator
L6495_RS14720	COG0833	amino acid
L6495_RS14725	COG1690	Belongs to the RtcB family
L6495_RS14735	COG1785	Belongs to the alkaline phosphatase family
L6495_RS14745	COG3655	Transcriptional regulator
L6495_RS14760	COG4377	Putative membrane peptidase family (DUF2324)
L6495_RS14770	COG3279	Response regulator of the LytR AlgR family
L6495_RS14780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS14785	COG0346	lactoylglutathione lyase activity
L6495_RS14810	COG0714	Associated with various cellular activities
L6495_RS14835	COG0463	Glycosyl transferase, family 2
L6495_RS14855	COG0463	Glycosyl transferase, family 2
L6495_RS14870	COG0753	catalase activity
L6495_RS14880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L6495_RS14890	COG1280	lysine exporter protein (LysE YggA)
L6495_RS14915	COG0714	Associated with various cellular activities
L6495_RS15040	COG0778	Nitroreductase
L6495_RS15045	COG1846	Transcriptional regulator
L6495_RS15080	COG1725	Transcriptional regulator
L6495_RS15100	COG0577	efflux transmembrane transporter activity
L6495_RS15100	COG1136	(ABC) transporter
L6495_RS15125	COG2207	Transcriptional regulator
L6495_RS15130	COG0456	acetyltransferase
L6495_RS15145	COG0697	spore germination
L6495_RS15150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS15195	COG0730	response to heat
L6495_RS15205	COG0833	amino acid
L6495_RS15215	COG4335	DNA alkylation repair
L6495_RS15250	COG0768	penicillin binding
L6495_RS15285	COG1984	allophanate hydrolase subunit 2
L6495_RS15290	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L6495_RS15295	COG1414	Transcriptional regulator
L6495_RS15315	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6495_RS15320	COG0640	Transcriptional regulator
L6495_RS15330	COG1960	acyl-CoA dehydrogenase activity
L6495_RS15345	COG3314	Sporulation integral membrane protein YlbJ
L6495_RS15370	COG0574	Belongs to the PEP-utilizing enzyme family
L6495_RS15370	COG3848	Pyruvate phosphate dikinase
L6495_RS15375	COG1819	glycosyl
L6495_RS15380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS15395	COG5577	PFAM Coat F domain
L6495_RS15400	COG3403	YqcI/YcgG family
L6495_RS15405	COG1280	lysine exporter protein (LysE YggA)
L6495_RS15410	COG1113	amino acid transport
L6495_RS15440	COG1063	alcohol dehydrogenase
L6495_RS15475	COG4974	Belongs to the 'phage' integrase family
L6495_RS15565	COG0753	catalase activity
L6495_RS15570	COG0598	Magnesium transport protein CorA
L6495_RS15610	COG0415	Belongs to the DNA photolyase family
L6495_RS15615	COG0288	reversible hydration of carbon dioxide
L6495_RS15625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L6495_RS15630	COG5609	conserved protein (DUF2294)
L6495_RS15645	COG0714	Associated with various cellular activities
L6495_RS15655	COG1575	Belongs to the MenA family. Type 1 subfamily
L6495_RS15665	COG0803	Belongs to the bacterial solute-binding protein 9 family
L6495_RS15670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L6495_RS15675	COG1121	(ABC) transporter
L6495_RS15690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS15700	COG0798	PFAM Bile acid sodium symporter
L6495_RS15705	COG0346	lactoylglutathione lyase activity
L6495_RS15710	COG0640	Transcriptional regulator
L6495_RS15720	COG0456	acetyltransferase
L6495_RS15730	COG3320	Male sterility
L6495_RS15730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6495_RS15735	COG1309	transcriptional regulator
L6495_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS15745	COG1522	sequence-specific DNA binding
L6495_RS15760	COG0346	lactoylglutathione lyase activity
L6495_RS15800	COG2814	Major facilitator Superfamily
L6495_RS15825	COG0745	RESPONSE REGULATOR receiver
L6495_RS15830	COG3850	Histidine kinase
L6495_RS15830	COG5002	protein histidine kinase activity
L6495_RS15855	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L6495_RS15875	COG1476	TRANSCRIPTIONal
L6495_RS15900	COG0789	Transcriptional regulator
L6495_RS15905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L6495_RS15920	COG1136	(ABC) transporter
L6495_RS15925	COG0577	efflux transmembrane transporter activity
L6495_RS15940	COG5002	protein histidine kinase activity
L6495_RS15940	COG3850	Histidine kinase
L6495_RS15950	COG2364	Membrane
L6495_RS15955	COG1846	Transcriptional regulator
L6495_RS15960	COG0456	acetyltransferase
L6495_RS15965	COG2808	Putative FMN-binding domain
L6495_RS15970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS15975	COG2271	Major facilitator Superfamily
L6495_RS15980	COG1556	Lactate utilization protein
L6495_RS15985	COG1139	Iron-sulfur cluster binding protein
L6495_RS15995	COG0583	DNA-binding transcription factor activity
L6495_RS16015	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6495_RS16030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L6495_RS16050	COG1595	DNA-templated transcription, initiation
L6495_RS16065	COG0662	Cupin 2, conserved barrel domain protein
L6495_RS16070	COG2207	Transcriptional regulator
L6495_RS16070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6495_RS16085	COG5632	N-Acetylmuramoyl-L-alanine amidase
L6495_RS16085	COG3409	Peptidoglycan-binding domain 1 protein
L6495_RS16380	COG2373	Large extracellular alpha-helical protein
L6495_RS16400	COG0477	Major facilitator Superfamily
L6495_RS16410	COG1846	Transcriptional regulator
L6495_RS16415	COG2814	Major facilitator Superfamily
L6495_RS16425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6495_RS16430	COG1131	(ABC) transporter
L6495_RS16450	COG2076	Multidrug Resistance protein
L6495_RS16455	COG1309	transcriptional regulator
L6495_RS16465	COG1476	TRANSCRIPTIONal
L6495_RS16480	COG2031	fatty acid transporter
L6495_RS16490	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6495_RS16525	COG1122	ATPase activity
L6495_RS16535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L6495_RS16550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L6495_RS16555	COG1288	antiporter activity
L6495_RS16565	COG3409	Peptidoglycan-binding domain 1 protein
L6495_RS16565	COG5632	N-Acetylmuramoyl-L-alanine amidase
L6495_RS16575	COG3620	sequence-specific DNA binding
L6495_RS16585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L6495_RS16605	COG1733	regulation of RNA biosynthetic process
L6495_RS16610	COG0778	Nitroreductase
L6495_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS16640	COG1131	(ABC) transporter
L6495_RS16665	COG1011	Hydrolase
L6495_RS16675	COG2365	Tyrosine phosphatase family
L6495_RS16700	COG0346	lactoylglutathione lyase activity
L6495_RS16705	COG1940	carbohydrate kinase activity
L6495_RS16715	COG0110	maltose O-acetyltransferase activity
L6495_RS16725	COG1136	(ABC) transporter
L6495_RS16725	COG0577	efflux transmembrane transporter activity
L6495_RS16745	COG0628	permease
L6495_RS16765	COG2226	methyltransferase
L6495_RS16775	COG0477	Major facilitator Superfamily
L6495_RS16805	COG1253	flavin adenine dinucleotide binding
L6495_RS16810	COG0789	Transcriptional regulator
L6495_RS16820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L6495_RS16850	COG0697	spore germination
L6495_RS16855	COG1357	PFAM Pentapeptide repeats (8 copies)
L6495_RS16860	COG3813	Protein conserved in bacteria
L6495_RS16870	COG2706	6-phosphogluconolactonase activity
L6495_RS16885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L6495_RS16890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L6495_RS16900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L6495_RS16915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6495_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS16975	COG0814	amino acid
L6495_RS17005	COG1393	Belongs to the ArsC family
L6495_RS17010	COG1733	regulation of RNA biosynthetic process
L6495_RS17015	COG2188	Transcriptional regulator
L6495_RS17020	COG0673	inositol 2-dehydrogenase activity
L6495_RS17025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L6495_RS17030	COG1733	regulation of RNA biosynthetic process
L6495_RS17035	COG1733	regulation of RNA biosynthetic process
L6495_RS17055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS17100	COG0318	PFAM AMP-dependent synthetase and ligase
L6495_RS17105	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6495_RS17110	COG1733	regulation of RNA biosynthetic process
L6495_RS17140	COG1191	sigma factor activity
L6495_RS17160	COG1309	transcriptional regulator
L6495_RS17180	COG3152	Membrane
L6495_RS17205	COG1151	hydroxylamine reductase activity
L6495_RS17215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS17220	COG3409	Peptidoglycan-binding domain 1 protein
L6495_RS17220	COG3757	hydrolase, family 25
L6495_RS17255	COG2072	flavoprotein involved in K transport
L6495_RS17290	COG1113	amino acid transport
L6495_RS17295	COG2814	Major facilitator Superfamily
L6495_RS17325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L6495_RS17330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6495_RS17350	COG3739	integral membrane protein
L6495_RS17355	COG0384	phenazine biosynthesis protein PhzF
L6495_RS17385	COG0583	DNA-binding transcription factor activity
L6495_RS17405	COG1193	negative regulation of DNA recombination
L6495_RS17420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L6495_RS17425	COG1164	Oligoendopeptidase f
L6495_RS17435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6495_RS17460	COG0584	glycerophosphoryl diester phosphodiesterase
L6495_RS17485	COG0640	Transcriptional regulator
L6495_RS17490	COG0604	alcohol dehydrogenase
L6495_RS17500	COG0457	Tetratricopeptide repeat
L6495_RS17510	COG2808	Putative FMN-binding domain
L6495_RS17520	COG0456	acetyltransferase
L6495_RS17520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6495_RS17530	COG0385	Bile acid
L6495_RS17535	COG0277	FAD linked oxidase domain protein
L6495_RS17565	COG1216	Glycosyl transferase, family 2
L6495_RS17570	COG1024	Enoyl-CoA hydratase
L6495_RS17580	COG1285	pathogenesis
L6495_RS17595	COG2514	catechol 2,3-dioxygenase activity
L6495_RS17600	COG2720	vancomycin resistance protein
L6495_RS17640	COG0716	FMN binding
L6495_RS17670	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS17680	COG0165	Argininosuccinate lyase
L6495_RS17695	COG4145	pantothenate transmembrane transporter activity
L6495_RS17770	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS17780	COG1657	PFAM Prenyltransferase squalene oxidase
L6495_RS17785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L6495_RS17790	COG2962	Rard protein
L6495_RS17795	COG3326	Membrane
L6495_RS17810	COG0489	protein tyrosine kinase activity
L6495_RS17820	COG0314	molybdopterin synthase activity
L6495_RS17825	COG0303	'Molybdopterin
L6495_RS17830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6495_RS17835	COG2116	formate transmembrane transporter activity
L6495_RS17845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L6495_RS17850	COG5609	conserved protein (DUF2294)
L6495_RS17855	COG2427	Protein of unknown function (DUF1641)
L6495_RS17860	COG3383	formate dehydrogenase (NAD+) activity
L6495_RS17865	COG0697	spore germination
L6495_RS17905	COG2226	methyltransferase
L6495_RS17910	COG4166	transmembrane transport
L6495_RS17920	COG4166	transmembrane transport
L6495_RS17925	COG4166	transmembrane transport
L6495_RS17930	COG1301	dicarboxylic acid transport
L6495_RS17935	COG1316	TRANSCRIPTIONal
L6495_RS17945	COG1595	DNA-templated transcription, initiation
L6495_RS17960	COG1131	(ABC) transporter
L6495_RS17985	COG0673	inositol 2-dehydrogenase activity
L6495_RS17990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L6495_RS17995	COG0187	DNA topoisomerase II activity
L6495_RS18000	COG1832	CoA-binding protein
L6495_RS18005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6495_RS18010	COG0745	RESPONSE REGULATOR receiver
L6495_RS18030	COG4841	protein insertion into membrane
L6495_RS18035	COG0824	Thioesterase
L6495_RS18065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6495_RS18075	COG1132	(ABC) transporter
L6495_RS18080	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L6495_RS18120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L6495_RS18135	COG0183	Belongs to the thiolase family
L6495_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
L6495_RS18145	COG1268	BioY protein
L6495_RS18150	COG0318	PFAM AMP-dependent synthetase and ligase
L6495_RS18210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS18225	COG0400	carboxylic ester hydrolase activity
L6495_RS18230	COG0346	lactoylglutathione lyase activity
L6495_RS18235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6495_RS18240	COG0069	glutamate synthase activity
L6495_RS18245	COG1902	pentaerythritol trinitrate reductase activity
L6495_RS18250	COG1329	Transcriptional regulator
L6495_RS18255	COG0010	Belongs to the arginase family
L6495_RS18280	COG2226	methyltransferase
L6495_RS18315	COG3344	reverse transcriptase
L6495_RS18325	COG4846	Membrane protein involved in cytochrome C biogenesis
L6495_RS18330	COG0785	Cytochrome C biogenesis protein
L6495_RS18340	COG1473	amidohydrolase
L6495_RS18350	COG1131	(ABC) transporter
L6495_RS18360	COG0583	DNA-binding transcription factor activity
L6495_RS18370	COG1346	cytolysis
L6495_RS18385	COG0730	response to heat
L6495_RS18410	COG1132	(ABC) transporter
L6495_RS18415	COG1132	(ABC) transporter
L6495_RS18445	COG3639	organic phosphonate transmembrane transporter activity
L6495_RS18450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
L6495_RS18455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6495_RS18460	COG0737	Belongs to the 5'-nucleotidase family
L6495_RS18470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6495_RS18490	COG1695	Transcriptional regulator
L6495_RS18495	COG0174	glutamine synthetase
L6495_RS18500	COG0789	Transcriptional regulator
L6495_RS18505	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L6495_RS18510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L6495_RS18515	COG2860	membrane
L6495_RS18520	COG0464	growth
L6495_RS18555	COG1388	LysM domain
L6495_RS18555	COG3584	3D domain protein
L6495_RS18560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6495_RS18560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L6495_RS18560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L6495_RS18565	COG1105	Belongs to the carbohydrate kinase PfkB family
L6495_RS18570	COG1349	DNA-binding transcription factor activity
L6495_RS18575	COG1979	alcohol dehydrogenase
L6495_RS18580	COG2322	membrane
L6495_RS18590	COG1113	amino acid transport
L6495_RS18605	COG1408	metallophosphoesterase
L6495_RS18610	COG2116	formate transmembrane transporter activity
L6495_RS18620	COG2217	Heavy metal translocating P-type atpase
L6495_RS18625	COG2608	mercury ion transmembrane transporter activity
L6495_RS18630	COG1937	Protein conserved in bacteria
L6495_RS18670	COG2819	hydrolase of the alpha beta superfamily
L6495_RS18675	COG1120	ATPase activity
L6495_RS18680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS18685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS18690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6495_RS18695	COG0708	Exodeoxyribonuclease III
L6495_RS18700	COG2169	Transcriptional regulator
L6495_RS18705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L6495_RS18710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L6495_RS18720	COG2364	Membrane
L6495_RS18735	COG2267	carboxylic ester hydrolase activity
L6495_RS18740	COG0346	lactoylglutathione lyase activity
L6495_RS18745	COG5001	Diguanylate cyclase
L6495_RS18745	COG3300	MHYT domain
L6495_RS18765	COG1380	Effector of murein hydrolase LrgA
L6495_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6495_RS18790	COG1404	Belongs to the peptidase S8 family
L6495_RS18795	COG3773	Cell wall hydrolase
L6495_RS18800	COG0562	UDP-galactopyranose mutase
L6495_RS18805	COG1368	sulfuric ester hydrolase activity
L6495_RS18810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6495_RS18830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L6495_RS18835	COG2814	Major facilitator Superfamily
L6495_RS18845	COG0640	Transcriptional regulator
L6495_RS18865	COG4550	Control of competence regulator ComK, YlbF/YmcA
L6495_RS18875	COG1013	pyruvate-flavodoxin oxidoreductase activity
L6495_RS18880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L6495_RS18880	COG0674	pyruvate-flavodoxin oxidoreductase activity
L6495_RS18890	COG2359	stage V sporulation protein S
L6495_RS18895	COG1692	metallophosphoesterase
L6495_RS18930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L6495_RS18935	COG1426	Protein conserved in bacteria
L6495_RS18950	COG0300	oxidoreductase activity
L6495_RS18955	COG0612	Peptidase, M16
L6495_RS18960	COG0612	Peptidase, M16
L6495_RS18965	COG1079	Belongs to the binding-protein-dependent transport system permease family
L6495_RS18970	COG4603	Belongs to the binding-protein-dependent transport system permease family
L6495_RS18975	COG3845	ABC transporter
L6495_RS18980	COG1744	ABC transporter substrate-binding protein PnrA-like
L6495_RS18985	COG2188	Transcriptional regulator
L6495_RS18990	COG1674	ftsk spoiiie
L6495_RS19000	COG0740	serine-type endopeptidase activity
L6495_RS19005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6495_RS19015	COG0527	aspartate kinase activity
L6495_RS19020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L6495_RS19025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L6495_RS19030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L6495_RS19035	COG1873	PFAM PRC-barrel domain
L6495_RS19040	COG0612	Peptidase, M16
L6495_RS19045	COG0726	polysaccharide deacetylase
L6495_RS19060	COG0196	riboflavin kinase activity
L6495_RS19075	COG1550	Protein conserved in bacteria
L6495_RS19085	COG1358	cellular component organization or biogenesis
L6495_RS19090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L6495_RS19095	COG0195	Participates in both transcription termination and antitermination
L6495_RS19125	COG0750	zinc metalloprotease
L6495_RS19135	COG4589	Belongs to the CDS family
L6495_RS19150	COG0528	UMP kinase activity
L6495_RS19180	COG4974	Belongs to the 'phage' integrase family
L6495_RS19190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L6495_RS19195	COG0758	DNA mediated transformation
L6495_RS19200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L6495_RS19240	COG1837	Belongs to the UPF0109 family
L6495_RS19250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L6495_RS19260	COG0552	protein localization to endoplasmic reticulum
L6495_RS19265	COG1196	nuclear chromosome segregation
L6495_RS19275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6495_RS19280	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS19285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L6495_RS19300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L6495_RS19305	COG1461	Dihydroxyacetone kinase
L6495_RS19310	COG1302	Protein conserved in bacteria
L6495_RS19325	COG1564	THIamine pyrophosphokinase
L6495_RS19330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L6495_RS19335	COG1162	GTPase activity
L6495_RS19340	COG0515	serine threonine protein kinase
L6495_RS19340	COG2815	serine threonine protein kinase
L6495_RS19345	COG0631	protein serine/threonine phosphatase activity
L6495_RS19355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L6495_RS19355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L6495_RS19365	COG0242	peptide deformylase activity
L6495_RS19370	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L6495_RS19375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L6495_RS19395	COG1561	YicC-like family, N-terminal region
L6495_RS19400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L6495_RS19410	COG0006	proline dipeptidase activity
L6495_RS19430	COG3069	C4-dicarboxylate transmembrane transporter activity
L6495_RS19490	COG0564	pseudouridine synthase activity
L6495_RS19510	COG3599	regulation of cell shape
L6495_RS19515	COG2302	S4 RNA-binding domain
L6495_RS19520	COG0762	integral membrane protein
L6495_RS19530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L6495_RS19535	COG1496	oxidoreductase activity
L6495_RS19540	COG1873	PFAM PRC-barrel domain
L6495_RS19545	COG1191	sigma factor activity
L6495_RS19550	COG1191	sigma factor activity
L6495_RS19560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L6495_RS19565	COG0849	cell division
L6495_RS19570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L6495_RS19585	COG0772	Belongs to the SEDS family
L6495_RS19600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L6495_RS19605	COG0768	penicillin binding
L6495_RS19610	COG0768	penicillin binding
L6495_RS19615	COG4839	cell division protein FtsL
L6495_RS19630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L6495_RS19645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L6495_RS19650	COG1399	metal-binding, possibly nucleic acid-binding protein
L6495_RS19660	COG3480	Lon protease (S16) C-terminal proteolytic domain
L6495_RS19665	COG1752	Esterase of the alpha-beta hydrolase superfamily
L6495_RS19670	COG3314	Sporulation integral membrane protein YlbJ
L6495_RS19680	COG0742	ribosomal rna small subunit methyltransferase
L6495_RS19695	COG3679	Belongs to the UPF0342 family
L6495_RS19700	COG0406	alpha-ribazole phosphatase activity
L6495_RS19715	COG2340	Cysteine-rich secretory protein family
L6495_RS19730	COG3336	cytochrome c oxidase
L6495_RS19765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L6495_RS19770	COG0772	Belongs to the SEDS family
L6495_RS19780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L6495_RS19785	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L6495_RS19795	COG4896	Protein conserved in bacteria
L6495_RS19810	COG1217	gtp-binding protein TYPA
L6495_RS19820	COG0483	inositol monophosphate 1-phosphatase activity
L6495_RS19840	COG1982	Orn Lys Arg decarboxylase major
L6495_RS19890	COG0022	dehydrogenase e1 component
L6495_RS19895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6495_RS19905	COG0242	peptide deformylase activity
L6495_RS19910	COG0561	phosphatase activity
L6495_RS19920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6495_RS19925	COG0569	domain protein
L6495_RS19945	COG0583	DNA-binding transcription factor activity
L6495_RS19950	COG0517	IMP dehydrogenase activity
L6495_RS19960	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
L6495_RS19970	COG4703	Protein of unknown function (DUF1797)
L6495_RS19985	COG2200	EAL domain
L6495_RS19990	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS19995	COG1408	metallophosphoesterase
L6495_RS20005	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
L6495_RS20040	COG2814	Major facilitator Superfamily
L6495_RS20060	COG3209	COG3209 Rhs family protein
L6495_RS20070	COG2205	protein histidine kinase activity
L6495_RS20080	COG0436	Aminotransferase
L6495_RS20085	COG1609	Transcriptional regulator
L6495_RS20090	COG3833	ABC-type maltose transport systems, permease component
L6495_RS20095	COG1175	transmembrane transport
L6495_RS20100	COG2182	Extracellular solute-binding protein
L6495_RS20110	COG0366	Alpha amylase catalytic
L6495_RS20115	COG3842	ATPase activity
L6495_RS20155	COG0183	Belongs to the thiolase family
L6495_RS20195	COG1695	Transcriptional regulator
L6495_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS20220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L6495_RS20225	COG0436	Aminotransferase
L6495_RS20260	COG2084	Dehydrogenase
L6495_RS20265	COG2199	diguanylate cyclase activity
L6495_RS20270	COG0778	Nitroreductase
L6495_RS20295	COG1263	PTS System
L6495_RS20295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS20295	COG2190	(PTS) system
L6495_RS20300	COG3711	transcriptional antiterminator
L6495_RS20310	COG2188	Transcriptional regulator
L6495_RS20320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L6495_RS20345	COG1547	Domain of unknown function (DUF309)
L6495_RS20350	COG0456	acetyltransferase
L6495_RS20360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L6495_RS20365	COG4086	secreted protein
L6495_RS20370	COG0561	phosphatase activity
L6495_RS20375	COG0697	spore germination
L6495_RS20390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6495_RS20415	COG0733	neurotransmitter:sodium symporter activity
L6495_RS20435	COG1686	Belongs to the peptidase S11 family
L6495_RS20440	COG1725	Transcriptional regulator
L6495_RS20445	COG1131	(ABC) transporter
L6495_RS20465	COG1846	Transcriptional regulator
L6495_RS20480	COG0598	Magnesium transport protein CorA
L6495_RS20505	COG4974	Belongs to the 'phage' integrase family
L6495_RS20515	COG0735	belongs to the Fur family
L6495_RS20520	COG1300	Membrane
L6495_RS20540	COG0667	Aldo Keto reductase
L6495_RS20545	COG0656	L-ascorbic acid biosynthetic process
L6495_RS20550	COG0456	acetyltransferase
L6495_RS20550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6495_RS20560	COG0737	Belongs to the 5'-nucleotidase family
L6495_RS20560	COG1525	nuclease
L6495_RS20560	COG4085	toxin activity
L6495_RS20570	COG0596	Alpha beta hydrolase
L6495_RS20575	COG2056	Na+-H+ antiporter family
L6495_RS20580	COG1609	Transcriptional regulator
L6495_RS20585	COG0454	-acetyltransferase
L6495_RS20590	COG1073	alpha beta
L6495_RS20605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L6495_RS20605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L6495_RS20610	COG0307	riboflavin synthase, alpha
L6495_RS20635	COG4106	trans-aconitate 2-methyltransferase activity
L6495_RS20640	COG2226	methyltransferase
L6495_RS20640	COG1073	alpha beta
L6495_RS20655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6495_RS20665	COG1757	Na H antiporter
L6495_RS20670	COG0737	Belongs to the 5'-nucleotidase family
L6495_RS20680	COG1522	sequence-specific DNA binding
L6495_RS20700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L6495_RS20725	COG0300	oxidoreductase activity
L6495_RS20730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS20735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6495_RS20740	COG1760	l-serine dehydratase
L6495_RS20745	COG1760	l-serine dehydratase
L6495_RS20765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L6495_RS20775	COG2195	Cleaves the N-terminal amino acid of tripeptides
L6495_RS20780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS20795	COG1376	ErfK ybiS ycfS ynhG family protein
L6495_RS20800	COG4129	membrane
L6495_RS20805	COG1126	abc transporter atp-binding protein
L6495_RS20810	COG0765	amino acid transport
L6495_RS20815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6495_RS20825	COG2816	NAD+ diphosphatase activity
L6495_RS20830	COG0772	Belongs to the SEDS family
L6495_RS20835	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6495_RS20840	COG0022	dehydrogenase e1 component
L6495_RS20845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6495_RS20850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L6495_RS20865	COG0280	phosphate acetyltransferase
L6495_RS20870	COG3829	transcription factor binding
L6495_RS20870	COG3290	protein histidine kinase activity
L6495_RS20880	COG0584	glycerophosphoryl diester phosphodiesterase
L6495_RS20885	COG3093	addiction module antidote protein HigA
L6495_RS20895	COG0745	RESPONSE REGULATOR receiver
L6495_RS20900	COG0750	zinc metalloprotease
L6495_RS20905	COG0497	DNA recombination
L6495_RS20915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L6495_RS20925	COG0142	geranyltranstransferase activity
L6495_RS20950	COG1302	Protein conserved in bacteria
L6495_RS20955	COG0439	Biotin carboxylase
L6495_RS20960	COG0511	ligase activity, forming carbon-carbon bonds
L6495_RS21005	COG3854	ATPases associated with a variety of cellular activities
L6495_RS21030	COG0006	proline dipeptidase activity
L6495_RS21045	COG3872	metal-dependent enzyme
L6495_RS21055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L6495_RS21090	COG0095	Lipoate-protein ligase
L6495_RS21095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6495_RS21100	COG1609	Transcriptional regulator
L6495_RS21110	COG2076	Multidrug Resistance protein
L6495_RS21115	COG2076	Multidrug Resistance protein
L6495_RS21150	COG1131	(ABC) transporter
L6495_RS21155	COG1725	Transcriptional regulator
L6495_RS21185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6495_RS21240	COG4970	Tfp pilus assembly protein FimT
L6495_RS21250	COG1459	type II secretion system
L6495_RS21255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L6495_RS21305	COG1410	methionine synthase
L6495_RS21305	COG0646	methionine synthase
L6495_RS21310	COG0646	methionine synthase
L6495_RS21310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L6495_RS21315	COG0626	cystathionine gamma-synthase activity
L6495_RS21320	COG0626	cystathionine gamma-synthase activity
L6495_RS21340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS21350	COG1940	carbohydrate kinase activity
L6495_RS21355	COG4483	Protein conserved in bacteria
L6495_RS21360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L6495_RS21365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L6495_RS21370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L6495_RS21375	COG0704	Plays a role in the regulation of phosphate uptake
L6495_RS21385	COG0581	inorganic phosphate transmembrane transporter activity
L6495_RS21390	COG0573	inorganic phosphate transmembrane transporter activity
L6495_RS21395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L6495_RS21405	COG0768	penicillin binding
L6495_RS21410	COG0477	Major facilitator Superfamily
L6495_RS21415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6495_RS21440	COG0735	belongs to the Fur family
L6495_RS21445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L6495_RS21450	COG1121	(ABC) transporter
L6495_RS21455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS21485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L6495_RS21490	COG2384	SAM-dependent methyltransferase
L6495_RS21495	COG2010	Cytochrome c
L6495_RS21500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L6495_RS21505	COG0358	DNA primase activity
L6495_RS21515	COG0517	IMP dehydrogenase activity
L6495_RS21530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L6495_RS21535	COG0295	cytidine deaminase activity
L6495_RS21540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L6495_RS21550	COG1480	7TM receptor with intracellular HD hydrolase
L6495_RS21555	COG1702	phosphate starvation-inducible protein PhoH
L6495_RS21570	COG1610	YqeY-like protein
L6495_RS21575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
L6495_RS21580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L6495_RS21585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L6495_RS21615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L6495_RS21620	COG1733	regulation of RNA biosynthetic process
L6495_RS21645	COG1466	dna polymerase III delta subunit
L6495_RS21655	COG0658	competence protein
L6495_RS21655	COG2333	competence protein COMEC
L6495_RS21660	COG2131	deaminase
L6495_RS21665	COG1596	polysaccharide export
L6495_RS21665	COG1555	photosystem II stabilization
L6495_RS21670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6495_RS21675	COG2226	methyltransferase
L6495_RS21680	COG0799	negative regulation of ribosome biogenesis
L6495_RS21685	COG1713	HD superfamily hydrolase involved in NAD metabolism
L6495_RS21695	COG1534	Rna-binding protein
L6495_RS21705	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L6495_RS21710	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L6495_RS21735	COG1595	DNA-templated transcription, initiation
L6495_RS21745	COG0778	Nitroreductase
L6495_RS21750	COG2357	RelA SpoT domain protein
L6495_RS21760	COG1785	Belongs to the alkaline phosphatase family
L6495_RS21770	COG2267	carboxylic ester hydrolase activity
L6495_RS21805	COG1404	Belongs to the peptidase S8 family
L6495_RS21810	COG3186	Phenylalanine-4-hydroxylase
L6495_RS21820	COG2514	catechol 2,3-dioxygenase activity
L6495_RS21825	COG2259	Doxx family
L6495_RS21865	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L6495_RS21875	COG1012	belongs to the aldehyde dehydrogenase family
L6495_RS21875	COG1454	alcohol dehydrogenase
L6495_RS21880	COG0626	cystathionine gamma-synthase activity
L6495_RS21885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6495_RS21910	COG0768	penicillin binding
L6495_RS21925	COG0826	peptidase U32
L6495_RS21930	COG0826	peptidase U32
L6495_RS21935	COG4122	O-methyltransferase activity
L6495_RS21940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L6495_RS21970	COG0628	permease
L6495_RS21990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L6495_RS22005	COG1104	cysteine desulfurase activity
L6495_RS22010	COG1959	2 iron, 2 sulfur cluster binding
L6495_RS22015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L6495_RS22025	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L6495_RS22065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L6495_RS22075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L6495_RS22075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L6495_RS22080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L6495_RS22085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L6495_RS22085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L6495_RS22095	COG2244	polysaccharide biosynthetic process
L6495_RS22100	COG2323	membrane
L6495_RS22110	COG1862	Preprotein translocase
L6495_RS22140	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L6495_RS22150	COG0697	spore germination
L6495_RS22155	COG0640	Transcriptional regulator
L6495_RS22180	COG0157	Belongs to the NadC ModD family
L6495_RS22185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L6495_RS22190	COG1104	cysteine desulfurase activity
L6495_RS22195	COG1827	regulation of RNA biosynthetic process
L6495_RS22200	COG2258	MOSC domain
L6495_RS22205	COG0077	Prephenate dehydratase
L6495_RS22210	COG0577	efflux transmembrane transporter activity
L6495_RS22215	COG0577	efflux transmembrane transporter activity
L6495_RS22220	COG1136	(ABC) transporter
L6495_RS22225	COG5002	protein histidine kinase activity
L6495_RS22230	COG0745	RESPONSE REGULATOR receiver
L6495_RS22240	COG3290	protein histidine kinase activity
L6495_RS22250	COG2868	ribosomal protein
L6495_RS22255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L6495_RS22260	COG1530	ribonuclease E activity
L6495_RS22265	COG1994	Peptidase M50
L6495_RS22270	COG0739	heme binding
L6495_RS22275	COG2894	cell division
L6495_RS22295	COG1077	Cell shape determining protein MreB Mrl
L6495_RS22335	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L6495_RS22335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L6495_RS22465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
L6495_RS22505	COG0285	dihydrofolate synthase activity
L6495_RS22520	COG1388	LysM domain
L6495_RS22530	COG0113	porphobilinogen synthase activity
L6495_RS22535	COG1587	Uroporphyrinogen-III synthase
L6495_RS22545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L6495_RS22555	COG1846	Transcriptional regulator
L6495_RS22560	COG1764	response to oxidative stress
L6495_RS22575	COG0470	DNA polymerase III
L6495_RS22575	COG1067	ATP-dependent peptidase activity
L6495_RS22625	COG0622	Phosphoesterase
L6495_RS22640	COG5401	PFAM Sporulation and spore germination
L6495_RS22655	COG2197	response regulator
L6495_RS22660	COG2233	PERMEase
L6495_RS22665	COG0402	S-adenosylhomocysteine deaminase activity
L6495_RS22670	COG1983	PspC domain protein
L6495_RS22675	COG1396	sequence-specific DNA binding
L6495_RS22680	COG0697	spore germination
L6495_RS22690	COG1959	2 iron, 2 sulfur cluster binding
L6495_RS22695	COG1668	transmembrane transport
L6495_RS22700	COG4152	abc transporter atp-binding protein
L6495_RS22705	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
L6495_RS22710	COG1360	Flagellar Motor Protein
L6495_RS22715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L6495_RS22720	COG1876	peptidase activity
L6495_RS22725	COG0824	Thioesterase
L6495_RS22730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L6495_RS22735	COG1053	succinate dehydrogenase
L6495_RS22740	COG2009	succinate dehydrogenase
L6495_RS22745	COG1719	4-vinyl reductase, 4VR
L6495_RS22755	COG3118	belongs to the thioredoxin family
L6495_RS22760	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L6495_RS22765	COG2086	electron transfer activity
L6495_RS22770	COG1024	Enoyl-CoA hydratase
L6495_RS22775	COG1309	transcriptional regulator
L6495_RS22780	COG0318	PFAM AMP-dependent synthetase and ligase
L6495_RS22800	COG2318	DinB family
L6495_RS22825	COG1131	(ABC) transporter
L6495_RS22830	COG2205	protein histidine kinase activity
L6495_RS22835	COG0745	RESPONSE REGULATOR receiver
L6495_RS22845	COG4895	conserved protein (DUF2196)
L6495_RS22850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L6495_RS22865	COG4509	Sortase family
L6495_RS22870	COG1120	ATPase activity
L6495_RS22885	COG5386	Cell surface protein
L6495_RS22890	COG5386	Cell surface protein
L6495_RS22895	COG1114	Component of the transport system for branched-chain amino acids
L6495_RS22900	COG1187	pseudouridine synthase activity
L6495_RS22910	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L6495_RS22910	COG1796	DNA polymerase
L6495_RS22915	COG1286	toxin biosynthetic process
L6495_RS22960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L6495_RS22970	COG1418	mRNA catabolic process
L6495_RS22980	COG2814	Major facilitator Superfamily
L6495_RS22985	COG1566	PFAM secretion protein HlyD family protein
L6495_RS22990	COG1309	transcriptional regulator
L6495_RS22995	COG1363	Peptidase, m42
L6495_RS23020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L6495_RS23030	COG1484	DNA-dependent DNA replication
L6495_RS23035	COG3611	Membrane attachment protein
L6495_RS23045	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
L6495_RS23050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L6495_RS23055	COG0237	dephospho-CoA kinase activity
L6495_RS23060	COG1971	Probably functions as a manganese efflux pump
L6495_RS23070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6495_RS23070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6495_RS23075	COG5002	protein histidine kinase activity
L6495_RS23080	COG0745	RESPONSE REGULATOR receiver
L6495_RS23100	COG0538	isocitrate dehydrogenase activity
L6495_RS23105	COG0372	Belongs to the citrate synthase family
L6495_RS23115	COG0628	permease
L6495_RS23120	COG3030	protein affecting phage T7 exclusion by the F plasmid
L6495_RS23145	COG1725	Transcriptional regulator
L6495_RS23150	COG0281	malic enzyme
L6495_RS23155	COG0587	DNA-directed DNA polymerase activity
L6495_RS23170	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L6495_RS23185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6495_RS23195	COG4109	DRTGG domain
L6495_RS23210	COG0006	proline dipeptidase activity
L6495_RS23245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS23250	COG0662	Cupin 2, conserved barrel domain protein
L6495_RS23265	COG1028	Short-chain dehydrogenase reductase Sdr
L6495_RS23270	COG0589	response to stress
L6495_RS23310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS23325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L6495_RS23330	COG0827	DNA restriction-modification system
L6495_RS23335	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L6495_RS23345	COG3874	Sporulation protein YtfJ
L6495_RS23360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L6495_RS23370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6495_RS23385	COG1104	cysteine desulfurase activity
L6495_RS23395	COG0583	DNA-binding transcription factor activity
L6495_RS23400	COG0697	spore germination
L6495_RS23405	COG1309	transcriptional regulator
L6495_RS23410	COG1956	GAF domain-containing protein
L6495_RS23415	COG0626	cystathionine gamma-synthase activity
L6495_RS23460	COG1595	DNA-templated transcription, initiation
L6495_RS23470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6495_RS23475	COG0454	-acetyltransferase
L6495_RS23480	COG0517	IMP dehydrogenase activity
L6495_RS23485	COG0123	including yeast histone deacetylase and acetoin utilization protein
L6495_RS23490	COG2267	carboxylic ester hydrolase activity
L6495_RS23500	COG0745	RESPONSE REGULATOR receiver
L6495_RS23510	COG0666	response to abiotic stimulus
L6495_RS23515	COG0745	RESPONSE REGULATOR receiver
L6495_RS23515	COG2972	Histidine kinase
L6495_RS23570	COG1609	Transcriptional regulator
L6495_RS23575	COG4851	CamS sex pheromone cAM373 precursor
L6495_RS23580	COG3118	belongs to the thioredoxin family
L6495_RS23590	COG2309	aminopeptidase activity
L6495_RS23600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS23605	COG0697	spore germination
L6495_RS23610	COG0789	Transcriptional regulator
L6495_RS23615	COG1695	Transcriptional regulator
L6495_RS23635	COG1674	ftsk spoiiie
L6495_RS23635	COG1674	ftsk spoiiie
L6495_RS23645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6495_RS23655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6495_RS23660	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
L6495_RS23665	COG1363	Peptidase, m42
L6495_RS23675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS23690	COG0510	thiamine kinase activity
L6495_RS23695	COG1523	belongs to the glycosyl hydrolase 13 family
L6495_RS23705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6495_RS23710	COG1349	DNA-binding transcription factor activity
L6495_RS23715	COG1187	pseudouridine synthase activity
L6495_RS23720	COG2244	polysaccharide biosynthetic process
L6495_RS23725	COG2081	HI0933 family
L6495_RS23735	COG2814	Major facilitator Superfamily
L6495_RS23745	COG3832	glyoxalase III activity
L6495_RS23765	COG1329	Transcriptional regulator
L6495_RS23790	COG0314	molybdopterin synthase activity
L6495_RS23805	COG1763	Mo-molybdopterin cofactor biosynthetic process
L6495_RS23810	COG0303	'Molybdopterin
L6495_RS23820	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6495_RS23825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L6495_RS23845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6495_RS23855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L6495_RS23900	COG2814	Major facilitator Superfamily
L6495_RS23905	COG3328	transposase activity
L6495_RS23910	COG0475	glutathione-regulated potassium exporter activity
L6495_RS23915	COG0490	domain, Protein
L6495_RS23920	COG0582	viral genome integration into host DNA
L6495_RS23930	COG1136	(ABC) transporter
L6495_RS23950	COG1242	4 iron, 4 sulfur cluster binding
L6495_RS23955	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L6495_RS23970	COG1794	racemase activity, acting on amino acids and derivatives
L6495_RS23995	COG2267	carboxylic ester hydrolase activity
L6495_RS24000	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L6495_RS24005	COG0671	phosphoesterase, PA-phosphatase related
L6495_RS24010	COG0438	transferase activity, transferring glycosyl groups
L6495_RS24020	COG0521	Mo-molybdopterin cofactor biosynthetic process
L6495_RS24070	COG3328	transposase activity
L6495_RS24090	COG5002	protein histidine kinase activity
L6495_RS24095	COG4191	Histidine kinase
L6495_RS24100	COG2267	carboxylic ester hydrolase activity
L6495_RS24105	COG1368	sulfuric ester hydrolase activity
L6495_RS24120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6495_RS24125	COG1116	anion transmembrane transporter activity
L6495_RS24130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6495_RS24155	COG0494	nUDIX hydrolase
L6495_RS24185	COG0288	reversible hydration of carbon dioxide
L6495_RS24190	COG1271	oxidase subunit
L6495_RS24195	COG1294	oxidase, subunit
L6495_RS24215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS24240	COG1842	Phage shock protein A
L6495_RS24275	COG0745	RESPONSE REGULATOR receiver
L6495_RS24305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L6495_RS24310	COG1597	lipid kinase activity
L6495_RS24335	COG0586	Pfam SNARE associated Golgi protein
L6495_RS24345	COG4977	sequence-specific DNA binding
L6495_RS24355	COG0577	efflux transmembrane transporter activity
L6495_RS24360	COG1136	(ABC) transporter
L6495_RS24365	COG2207	Transcriptional regulator
L6495_RS24365	COG3708	Transcriptional regulator
L6495_RS24380	COG0745	RESPONSE REGULATOR receiver
L6495_RS24385	COG2205	protein histidine kinase activity
L6495_RS24390	COG0577	efflux transmembrane transporter activity
L6495_RS24395	COG0577	efflux transmembrane transporter activity
L6495_RS24400	COG1136	(ABC) transporter
L6495_RS24405	COG0577	efflux transmembrane transporter activity
L6495_RS24430	COG2188	Transcriptional regulator
L6495_RS24450	COG3964	amidohydrolase
L6495_RS24475	COG4948	Mandelate Racemase Muconate Lactonizing
L6495_RS24485	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L6495_RS24490	COG0596	Alpha beta hydrolase
L6495_RS24500	COG1169	isochorismate synthase
L6495_RS24505	COG1575	Belongs to the MenA family. Type 1 subfamily
L6495_RS24510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L6495_RS24625	COG0058	SHG alpha-glucan phosphorylase activity
L6495_RS24635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L6495_RS24655	COG1404	Belongs to the peptidase S8 family
L6495_RS24670	COG1595	DNA-templated transcription, initiation
L6495_RS24765	COG0544	peptidyl-prolyl cis-trans isomerase activity
L6495_RS24800	COG1285	pathogenesis
L6495_RS24805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L6495_RS24820	COG2155	Conserved Protein
L6495_RS24825	COG1098	S1 RNA binding domain
L6495_RS24830	COG0436	Aminotransferase
L6495_RS24835	COG1522	sequence-specific DNA binding
L6495_RS24840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L6495_RS24845	COG2267	carboxylic ester hydrolase activity
L6495_RS24855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L6495_RS24875	COG5018	Exonuclease
L6495_RS24880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6495_RS24905	COG2050	protein possibly involved in aromatic compounds catabolism
L6495_RS24915	COG1268	BioY protein
L6495_RS24920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L6495_RS24925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L6495_RS24940	COG3584	3D domain protein
L6495_RS24955	COG1252	NADH dehydrogenase
L6495_RS24965	COG3708	Transcriptional regulator
L6495_RS24980	COG1683	Conserved Protein
L6495_RS24990	COG0316	Belongs to the HesB IscA family
L6495_RS25020	COG1252	NADH dehydrogenase
L6495_RS25030	COG2274	protein secretion by the type I secretion system
L6495_RS25035	COG0390	transport system, permease component
L6495_RS25045	COG2824	Alkylphosphonate utilization operon protein PhnA
L6495_RS25065	COG4837	Protein of unknown function (DUF1462)
L6495_RS25070	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L6495_RS25080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6495_RS25085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L6495_RS25095	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6495_RS25100	COG0647	UMP catabolic process
L6495_RS25110	COG2445	Protein of unknown function DUF86
L6495_RS25115	COG1494	fructose-1,6-bisphosphatase
L6495_RS25130	COG4470	Protein conserved in bacteria
L6495_RS25140	COG0789	Transcriptional regulator
L6495_RS25145	COG4377	Putative membrane peptidase family (DUF2324)
L6495_RS25170	COG0739	heme binding
L6495_RS25180	COG3377	Domain of unknown function (DUF1805)
L6495_RS25185	COG0737	Belongs to the 5'-nucleotidase family
L6495_RS25195	COG0719	Fe-S assembly protein
L6495_RS25200	COG0822	iron-sulfur transferase activity
L6495_RS25205	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L6495_RS25210	COG0719	Fe-S assembly protein
L6495_RS25215	COG0396	ATPase activity
L6495_RS25220	COG1464	Belongs to the NlpA lipoprotein family
L6495_RS25225	COG1464	Belongs to the NlpA lipoprotein family
L6495_RS25230	COG2011	ABC-type metal ion transport system permease component
L6495_RS25245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6495_RS25250	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L6495_RS25260	COG1393	Belongs to the ArsC family
L6495_RS25325	COG1396	sequence-specific DNA binding
L6495_RS25335	COG1309	transcriptional regulator
L6495_RS25340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6495_RS25345	COG1960	acyl-CoA dehydrogenase activity
L6495_RS25350	COG0183	Belongs to the thiolase family
L6495_RS25355	COG1024	Enoyl-CoA hydratase
L6495_RS25355	COG1250	3-hydroxyacyl-CoA dehydrogenase
L6495_RS25365	COG1686	Belongs to the peptidase S11 family
L6495_RS25380	COG0011	TIGRFAM Protein of
L6495_RS25385	COG0840	transmembrane signaling receptor activity
L6495_RS25400	COG2814	Major facilitator Superfamily
L6495_RS25405	COG0531	amino acid
L6495_RS25430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6495_RS25475	COG0586	Pfam SNARE associated Golgi protein
L6495_RS25485	COG1376	ErfK ybiS ycfS ynhG family protein
L6495_RS25490	COG0745	RESPONSE REGULATOR receiver
L6495_RS25495	COG5002	protein histidine kinase activity
L6495_RS25520	COG0840	transmembrane signaling receptor activity
L6495_RS25525	COG2151	metal-sulfur cluster biosynthetic enzyme
L6495_RS25530	COG3227	Zinc metalloprotease (Elastase)
L6495_RS25535	COG1741	Belongs to the pirin family
L6495_RS25550	COG0475	glutathione-regulated potassium exporter activity
L6495_RS25555	COG0490	domain, Protein
L6495_RS25560	COG1115	amino acid carrier protein
L6495_RS25565	COG0783	Belongs to the Dps family
L6495_RS25580	COG1611	Belongs to the LOG family
L6495_RS25595	COG2311	Membrane
L6495_RS25600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS25605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS25610	COG1115	amino acid carrier protein
L6495_RS25615	COG1115	amino acid carrier protein
L6495_RS25620	COG2910	NAD(P)H-binding
L6495_RS25645	COG0656	L-ascorbic acid biosynthetic process
L6495_RS25650	COG2814	Major facilitator Superfamily
L6495_RS25655	COG1733	regulation of RNA biosynthetic process
L6495_RS25665	COG1252	NADH dehydrogenase
L6495_RS25675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L6495_RS25690	COG0840	transmembrane signaling receptor activity
L6495_RS25690	COG3290	protein histidine kinase activity
L6495_RS25725	COG0488	(ABC) transporter
L6495_RS25730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6495_RS25740	COG2814	Major facilitator Superfamily
L6495_RS25790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6495_RS25795	COG0697	spore germination
L6495_RS25815	COG0557	exoribonuclease II activity
L6495_RS25820	COG1647	Serine aminopeptidase, S33
L6495_RS25825	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L6495_RS25830	COG1346	cytolysis
L6495_RS25865	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L6495_RS25880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L6495_RS25905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6495_RS25920	COG2323	membrane
L6495_RS25930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6495_RS25940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L6495_RS25950	COG1051	belongs to the nudix hydrolase family
L6495_RS25960	COG0492	ferredoxin-NADP+ reductase activity
L6495_RS25965	COG0457	Tetratricopeptide repeat
L6495_RS25970	COG0110	maltose O-acetyltransferase activity
L6495_RS25990	COG1950	PFAM Membrane protein of
L6495_RS26000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L6495_RS26005	COG0556	nucleotide-excision repair
L6495_RS26020	COG0789	Transcriptional regulator
L6495_RS26045	COG2855	membrane
L6495_RS26050	COG0583	DNA-binding transcription factor activity
L6495_RS26060	COG0655	NAD(P)H dehydrogenase (quinone) activity
L6495_RS26065	COG0488	(ABC) transporter
L6495_RS26075	COG1132	(ABC) transporter
L6495_RS26085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6495_RS26090	COG0793	Belongs to the peptidase S41A family
L6495_RS26090	COG3409	Peptidoglycan-binding domain 1 protein
L6495_RS26095	COG2177	Part of the ABC transporter FtsEX involved in
L6495_RS26100	COG2884	Cell division ATP-binding protein ftsE
L6495_RS26120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L6495_RS26125	COG1278	Cold shock
L6495_RS26130	COG1040	competence protein
L6495_RS26135	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L6495_RS26145	COG1733	regulation of RNA biosynthetic process
L6495_RS26150	COG1307	EDD domain protein, DegV family
L6495_RS26155	COG1739	Uncharacterized protein family UPF0029
L6495_RS26160	COG1316	TRANSCRIPTIONal
L6495_RS26165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L6495_RS26170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L6495_RS26175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L6495_RS26185	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L6495_RS26185	COG3933	PFAM sigma-54 factor interaction domain-containing protein
L6495_RS26205	COG1486	melibiose metabolic process
L6495_RS26210	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6495_RS26215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6495_RS26225	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L6495_RS26245	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6495_RS26255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6495_RS26260	COG1301	dicarboxylic acid transport
L6495_RS26270	COG0346	lactoylglutathione lyase activity
L6495_RS26290	COG1511	domain protein
L6495_RS26295	COG0583	DNA-binding transcription factor activity
L6495_RS26300	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
L6495_RS26310	COG1271	oxidase subunit
L6495_RS26315	COG1294	oxidase, subunit
L6495_RS26320	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6495_RS26360	COG1620	l-lactate permease
L6495_RS26370	COG2389	metal-binding protein
L6495_RS26380	COG1368	sulfuric ester hydrolase activity
L6495_RS26390	COG0791	NLP P60 protein
L6495_RS26390	COG1388	LysM domain
L6495_RS26395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6495_RS26405	COG1215	transferase activity, transferring glycosyl groups
L6495_RS26415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6495_RS26420	COG3584	3D domain protein
L6495_RS26420	COG1388	LysM domain
L6495_RS26430	COG4715	Zinc finger, swim domain protein
L6495_RS26435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6495_RS26480	COG0577	efflux transmembrane transporter activity
L6495_RS26485	COG1136	(ABC) transporter
L6495_RS26520	COG3850	Histidine kinase
L6495_RS26520	COG5002	protein histidine kinase activity
L6495_RS26525	COG0745	RESPONSE REGULATOR receiver
L6495_RS26530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L6495_RS26550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L6495_RS26560	COG0438	transferase activity, transferring glycosyl groups
L6495_RS26580	COG0438	transferase activity, transferring glycosyl groups
L6495_RS26585	COG0438	transferase activity, transferring glycosyl groups
L6495_RS26590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L6495_RS26595	COG0151	Belongs to the GarS family
L6495_RS26605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L6495_RS26610	COG1086	Polysaccharide biosynthesis protein
L6495_RS26615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L6495_RS26620	COG4464	protein tyrosine phosphatase activity
L6495_RS26625	COG0489	protein tyrosine kinase activity
L6495_RS26630	COG3944	biosynthesis protein
L6495_RS26635	COG0489	protein tyrosine kinase activity
L6495_RS26650	COG1609	Transcriptional regulator
L6495_RS26660	COG0739	heme binding
L6495_RS26675	COG3279	Response regulator of the LytR AlgR family
L6495_RS26680	COG2385	sporulation resulting in formation of a cellular spore
L6495_RS26695	COG4836	Membrane
L6495_RS26700	COG1007	ATP synthesis coupled electron transport
L6495_RS26710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L6495_RS26720	COG0839	Belongs to the complex I subunit 6 family
L6495_RS26740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L6495_RS26755	COG5001	Diguanylate cyclase
L6495_RS26755	COG3300	MHYT domain
L6495_RS26805	COG0356	it plays a direct role in the translocation of protons across the membrane
L6495_RS26840	COG0698	ribose 5-phosphate isomerase
L6495_RS26850	COG2190	(PTS) system
L6495_RS26855	COG2259	Doxx family
L6495_RS26860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L6495_RS26880	COG0009	L-threonylcarbamoyladenylate synthase
L6495_RS26895	COG2890	protein-(glutamine-N5) methyltransferase activity
L6495_RS26915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L6495_RS26920	COG1494	fructose-1,6-bisphosphatase
L6495_RS26940	COG4821	SIS domain
L6495_RS26960	COG1960	acyl-CoA dehydrogenase activity
L6495_RS26965	COG1960	acyl-CoA dehydrogenase activity
L6495_RS26970	COG1250	3-hydroxyacyl-CoA dehydrogenase
L6495_RS26975	COG0183	Belongs to the thiolase family
L6495_RS26980	COG2181	nitrate reductase activity
L6495_RS26980	COG0247	lactate metabolic process
L6495_RS26985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6495_RS26995	COG3300	MHYT domain
L6495_RS26995	COG5001	Diguanylate cyclase
L6495_RS27015	COG2197	response regulator
L6495_RS27020	COG4585	Histidine kinase
L6495_RS27025	COG0842	Transport permease protein
L6495_RS27030	COG1131	(ABC) transporter
L6495_RS27035	COG0024	Methionine aminopeptidase
L6495_RS27040	COG2234	aminopeptidase activity
L6495_RS27060	COG1595	DNA-templated transcription, initiation
L6495_RS27070	COG4506	Protein conserved in bacteria
L6495_RS27075	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6495_RS27090	COG0010	Belongs to the arginase family
L6495_RS27100	COG2814	Major facilitator Superfamily
L6495_RS27105	COG0789	Transcriptional regulator
L6495_RS27110	COG0584	glycerophosphoryl diester phosphodiesterase
L6495_RS27115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6495_RS27125	COG1994	Peptidase M50
L6495_RS27135	COG1078	dGTPase activity
L6495_RS27140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6495_RS27145	COG1120	ATPase activity
L6495_RS27150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS27155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6495_RS27175	COG0095	Lipoate-protein ligase
L6495_RS27180	COG0280	phosphate acetyltransferase
L6495_RS27195	COG3773	Cell wall hydrolase
L6495_RS27205	COG2363	Small membrane protein
L6495_RS27215	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L6495_RS27220	COG2233	PERMEase
L6495_RS27225	COG0561	phosphatase activity
L6495_RS27230	COG2814	Major facilitator Superfamily
L6495_RS27240	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6495_RS27245	COG1131	(ABC) transporter
L6495_RS27250	COG2755	lipolytic protein G-D-S-L family
L6495_RS27255	COG1609	Transcriptional regulator
L6495_RS27265	COG0460	homoserine dehydrogenase
L6495_RS27275	COG2873	o-acetylhomoserine
L6495_RS27280	COG1011	Hydrolase
L6495_RS27285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L6495_RS27295	COG2197	response regulator
L6495_RS27300	COG4585	Histidine kinase
L6495_RS27300	COG2203	Gaf domain
L6495_RS27305	COG0351	phosphomethylpyrimidine kinase
L6495_RS27310	COG3706	GGDEF domain
L6495_RS27315	COG2879	small protein
L6495_RS27320	COG1966	Carbon starvation protein
L6495_RS27325	COG3279	Response regulator of the LytR AlgR family
L6495_RS27330	COG0477	Major facilitator Superfamily
L6495_RS27355	COG0840	transmembrane signaling receptor activity
L6495_RS27365	COG1607	acyl-coa hydrolase
L6495_RS27370	COG1216	Glycosyl transferase, family 2
L6495_RS27380	COG0488	(ABC) transporter
L6495_RS27400	COG0463	Glycosyl transferase, family 2
L6495_RS27405	COG1309	transcriptional regulator
L6495_RS27410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L6495_RS27415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6495_RS27415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6495_RS27420	COG0628	permease
L6495_RS27435	COG3279	Response regulator of the LytR AlgR family
L6495_RS27440	COG3275	phosphorelay sensor kinase activity
L6495_RS27445	COG2814	Major facilitator Superfamily
L6495_RS27450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6495_RS27455	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
L6495_RS27460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6495_RS27510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L6495_RS27515	COG1272	protein, Hemolysin III
L6495_RS27545	COG1164	Oligoendopeptidase f
L6495_RS27555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6495_RS27585	COG4974	Belongs to the 'phage' integrase family
L6495_RS27645	COG1196	nuclear chromosome segregation
L6495_RS27665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6495_RS27670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L6495_RS27675	COG4853	Protein conserved in bacteria
L6495_RS27680	COG4863	YycH protein
L6495_RS27685	COG5002	protein histidine kinase activity
L6495_RS27690	COG0745	RESPONSE REGULATOR receiver
L6495_RS27720	COG0305	Participates in initiation and elongation during chromosome replication
L6495_RS27730	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L6495_RS27735	COG4241	membrane
L6495_RS27745	COG0629	single-stranded DNA binding
L6495_RS27755	COG0012	GTP binding
L6495_RS27760	COG4481	Protein conserved in bacteria
L6495_RS27765	COG0668	transmembrane transport
L6495_RS27775	COG1475	DNA binding
L6495_RS27780	COG1192	Involved in chromosome partitioning
L6495_RS27805	COG1847	R3H domain protein
L6495_RS27810	COG0706	membrane insertase activity
L6495_RS27820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L6495_RS27830	COG1335	isochorismatase
L6495_RS27835	COG4990	cell redox homeostasis
L6495_RS27840	COG0745	RESPONSE REGULATOR receiver
L6495_RS27875	COG4974	Belongs to the 'phage' integrase family
L6495_RS27890	COG0457	Tetratricopeptide repeat
L6495_RS28010	COG3344	reverse transcriptase
L6495_RS28030	COG3344	reverse transcriptase
L6495_RS28145	COG1396	sequence-specific DNA binding
L6495_RS28180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L6495_RS28185	COG0582	viral genome integration into host DNA
L6495_RS28215	COG2003	Belongs to the UPF0758 family
L6495_RS28230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L6495_RS28295	COG3397	chitin binding
L6495_RS28330	COG3103	Sh3 type 3 domain protein
L6495_RS28330	COG1388	LysM domain
L6495_RS28330	COG0791	NLP P60 protein
L6495_RS28375	COG0640	Transcriptional regulator
L6495_RS28925	COG1609	Transcriptional regulator
L6495_RS28930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6495_RS28930	COG1263	PTS System
L6495_RS28935	COG1621	beta-fructofuranosidase activity
L6495_RS28940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L6495_RS28970	COG2311	Membrane
L6495_RS29000	COG0776	regulation of translation
L6495_RS29035	COG2002	toxin-antitoxin pair type II binding
L6495_RS29070	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L6495_RS29140	COG3708	Transcriptional regulator
L6495_RS29140	COG2207	Transcriptional regulator
L6495_RS29155	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6495_RS29180	COG1733	regulation of RNA biosynthetic process
L6495_RS29190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L6495_RS29200	COG1181	Belongs to the D-alanine--D-alanine ligase family
L6495_RS29200	COG2918	glutathione biosynthetic process