locus-tag	class	description
L6451_RS00010	COG0592	DNA-directed DNA polymerase activity
L6451_RS00015	COG2501	S4 domain
L6451_RS00025	COG0187	DNA topoisomerase II activity
L6451_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L6451_RS00065	COG0516	GMP reductase activity
L6451_RS00065	COG0517	IMP dehydrogenase activity
L6451_RS00070	COG1686	Belongs to the peptidase S11 family
L6451_RS00100	COG1428	Deoxynucleoside kinase
L6451_RS00105	COG1428	Deoxynucleoside kinase
L6451_RS00110	COG1335	isochorismatase
L6451_RS00115	COG0590	tRNA wobble adenosine to inosine editing
L6451_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L6451_RS00180	COG1982	Orn Lys Arg decarboxylase major
L6451_RS00190	COG0470	DNA polymerase III
L6451_RS00195	COG1774	PSP1 C-terminal conserved region
L6451_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L6451_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L6451_RS00220	COG2002	toxin-antitoxin pair type II binding
L6451_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6451_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6451_RS00230	COG0084	hydrolase, TatD family'
L6451_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L6451_RS00250	COG4466	Protein conserved in bacteria
L6451_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L6451_RS00270	COG0251	oxidation-reduction process
L6451_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L6451_RS00305	COG2002	toxin-antitoxin pair type II binding
L6451_RS00310	COG2244	polysaccharide biosynthetic process
L6451_RS00315	COG3956	TIGRFAM MazG family protein
L6451_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L6451_RS00340	COG1098	S1 RNA binding domain
L6451_RS00355	COG2208	phosphoserine phosphatase activity
L6451_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L6451_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L6451_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6451_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L6451_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
L6451_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6451_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L6451_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L6451_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L6451_RS00420	COG1396	sequence-specific DNA binding
L6451_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L6451_RS00515	COG3880	PFAM UvrB UvrC protein
L6451_RS00525	COG0542	response to heat
L6451_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L6451_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
L6451_RS00560	COG1045	serine acetyltransferase
L6451_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L6451_RS00580	COG3688	RNA-binding protein containing a PIN domain
L6451_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L6451_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
L6451_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L6451_RS00625	COG2813	Specifically methylates the guanine in position
L6451_RS00640	COG1358	cellular component organization or biogenesis
L6451_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
L6451_RS00770	COG0201	protein transport
L6451_RS00780	COG0024	Methionine aminopeptidase
L6451_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L6451_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L6451_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L6451_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6451_RS00855	COG0489	protein tyrosine kinase activity
L6451_RS00865	COG2194	sulfuric ester hydrolase activity
L6451_RS00870	COG0726	polysaccharide deacetylase
L6451_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L6451_RS00955	COG4856	YbbR-like protein
L6451_RS00975	COG0596	Alpha beta hydrolase
L6451_RS00995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L6451_RS01070	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS01075	COG2011	ABC-type metal ion transport system permease component
L6451_RS01085	COG1464	Belongs to the NlpA lipoprotein family
L6451_RS01090	COG0604	alcohol dehydrogenase
L6451_RS01100	COG0277	FAD linked oxidase domain protein
L6451_RS01105	COG2271	Major facilitator Superfamily
L6451_RS01115	COG2814	Major facilitator Superfamily
L6451_RS01130	COG0601	transmembrane transport
L6451_RS01135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6451_RS01140	COG0444	Belongs to the ABC transporter superfamily
L6451_RS01145	COG4608	Belongs to the ABC transporter superfamily
L6451_RS01150	COG4166	transmembrane transport
L6451_RS01160	COG2207	Transcriptional regulator
L6451_RS01170	COG1309	transcriptional regulator
L6451_RS01180	COG4166	transmembrane transport
L6451_RS01185	COG4166	transmembrane transport
L6451_RS01190	COG0656	L-ascorbic acid biosynthetic process
L6451_RS01195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6451_RS01210	COG4149	molybdate abc transporter
L6451_RS01215	COG0725	ABC transporter, periplasmic molybdate-binding protein
L6451_RS01220	COG1910	domain protein
L6451_RS01235	COG0697	spore germination
L6451_RS01250	COG0204	Acyl-transferase
L6451_RS01260	COG1609	Transcriptional regulator
L6451_RS01270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS01280	COG0084	hydrolase, TatD family'
L6451_RS01290	COG5298	Protein conserved in bacteria
L6451_RS01315	COG0488	(ABC) transporter
L6451_RS01320	COG4585	Histidine kinase
L6451_RS01325	COG2197	response regulator
L6451_RS01330	COG1131	(ABC) transporter
L6451_RS01335	COG1511	domain protein
L6451_RS01335	COG0842	Transport permease protein
L6451_RS01340	COG0842	Transport permease protein
L6451_RS01355	COG0747	negative chemotaxis
L6451_RS01360	COG0601	transmembrane transport
L6451_RS01365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6451_RS01370	COG0444	Belongs to the ABC transporter superfamily
L6451_RS01375	COG4608	Belongs to the ABC transporter superfamily
L6451_RS01380	COG0561	phosphatase activity
L6451_RS01410	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L6451_RS01415	COG0179	Fumarylacetoacetate (FAA) hydrolase
L6451_RS01425	COG2814	Major facilitator Superfamily
L6451_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L6451_RS01445	COG4294	response to UV
L6451_RS01450	COG0457	Tetratricopeptide repeat
L6451_RS01450	COG0705	Rhomboid family
L6451_RS01460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L6451_RS01465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L6451_RS01470	COG0864	Transcriptional regulator
L6451_RS01475	COG2337	Toxic component of a toxin-antitoxin (TA) module
L6451_RS01480	COG2183	response to ionizing radiation
L6451_RS01575	COG0802	atpase or kinase
L6451_RS01580	COG1214	PFAM Peptidase M22, glycoprotease
L6451_RS01585	COG0456	acetyltransferase
L6451_RS01595	COG0488	(ABC) transporter
L6451_RS01610	COG1266	CAAX protease self-immunity
L6451_RS01630	COG2252	PERMEase
L6451_RS01640	COG5002	protein histidine kinase activity
L6451_RS01665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L6451_RS01740	COG2205	protein histidine kinase activity
L6451_RS01745	COG0745	RESPONSE REGULATOR receiver
L6451_RS01765	COG0697	spore germination
L6451_RS01795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L6451_RS01800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L6451_RS01805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L6451_RS01815	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L6451_RS01830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L6451_RS01840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L6451_RS01850	COG0151	Belongs to the GarS family
L6451_RS01875	COG0210	DNA helicase
L6451_RS01885	COG4851	CamS sex pheromone cAM373 precursor
L6451_RS01905	COG1335	isochorismatase
L6451_RS01910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L6451_RS01920	COG1464	Belongs to the NlpA lipoprotein family
L6451_RS01935	COG0003	Pfam Anion-transporting ATPase
L6451_RS01940	COG1846	Transcriptional regulator
L6451_RS01945	COG4682	membrane
L6451_RS01965	COG1597	lipid kinase activity
L6451_RS01970	COG0546	phosphoglycolate phosphatase activity
L6451_RS01975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L6451_RS01985	COG1012	belongs to the aldehyde dehydrogenase family
L6451_RS01990	COG2076	Multidrug Resistance protein
L6451_RS02000	COG2309	aminopeptidase activity
L6451_RS02015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS02020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L6451_RS02025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L6451_RS02035	COG4807	Protein conserved in bacteria
L6451_RS02060	COG1757	Na H antiporter
L6451_RS02065	COG1473	amidohydrolase
L6451_RS02080	COG0450	alkyl hydroperoxide reductase
L6451_RS02100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS02105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS02110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6451_RS02125	COG0166	Belongs to the GPI family
L6451_RS02170	COG3541	Predicted nucleotidyltransferase
L6451_RS02180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6451_RS02180	COG0723	plastoquinol--plastocyanin reductase activity
L6451_RS02205	COG0765	amino acid transport
L6451_RS02210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6451_RS02220	COG0840	transmembrane signaling receptor activity
L6451_RS02225	COG0840	transmembrane signaling receptor activity
L6451_RS02250	COG0366	Alpha amylase catalytic
L6451_RS02255	COG2190	(PTS) system
L6451_RS02255	COG1263	PTS System
L6451_RS02255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS02300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6451_RS02310	COG1116	anion transmembrane transporter activity
L6451_RS02315	COG0488	(ABC) transporter
L6451_RS02365	COG2270	Major facilitator Superfamily
L6451_RS02395	COG2310	stress, protein
L6451_RS02400	COG2310	stress, protein
L6451_RS02405	COG2310	stress, protein
L6451_RS02410	COG0861	Integral membrane protein TerC family
L6451_RS02420	COG3853	Toxic anion resistance protein (TelA)
L6451_RS02435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L6451_RS02445	COG1295	ribonuclease BN
L6451_RS02450	COG2217	Heavy metal translocating P-type atpase
L6451_RS02455	COG0697	spore germination
L6451_RS02465	COG0681	Belongs to the peptidase S26 family
L6451_RS02475	COG0586	Pfam SNARE associated Golgi protein
L6451_RS02490	COG3871	stress protein (general stress protein 26)
L6451_RS02495	COG0387	Pfam Sodium calcium exchanger
L6451_RS02505	COG0535	radical SAM domain protein
L6451_RS02525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L6451_RS02530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L6451_RS02535	COG0101	tRNA pseudouridine synthase activity
L6451_RS02555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6451_RS02585	COG1263	PTS System
L6451_RS02585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS02590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6451_RS02610	COG0463	Glycosyl transferase, family 2
L6451_RS02620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L6451_RS02635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L6451_RS02655	COG1228	amidohydrolase
L6451_RS02660	COG1090	epimerase
L6451_RS02690	COG1988	membrane-bound metal-dependent
L6451_RS02695	COG1194	a g-specific adenine glycosylase
L6451_RS02720	COG1132	(ABC) transporter
L6451_RS02725	COG4129	membrane
L6451_RS02730	COG0067	glutamate synthase
L6451_RS02730	COG0070	glutamate synthase
L6451_RS02730	COG0069	glutamate synthase activity
L6451_RS02740	COG4555	ABC transporter
L6451_RS02760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L6451_RS02765	COG0735	belongs to the Fur family
L6451_RS02910	COG1201	RNA secondary structure unwinding
L6451_RS02985	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6451_RS03005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
L6451_RS03010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L6451_RS03020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L6451_RS03030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L6451_RS03035	COG1716	ATPase activity
L6451_RS03035	COG5001	Diguanylate cyclase
L6451_RS03040	COG2766	serine protein kinase
L6451_RS03060	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6451_RS03070	COG1585	Membrane protein implicated in regulation of membrane protease activity
L6451_RS03075	COG2268	Band 7 protein
L6451_RS03085	COG3290	protein histidine kinase activity
L6451_RS03090	COG4565	transcriptional regulatory protein
L6451_RS03095	COG2851	Citrate transporter
L6451_RS03115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L6451_RS03120	COG3842	ATPase activity
L6451_RS03125	COG1175	transmembrane transport
L6451_RS03130	COG0395	ABC-type sugar transport system, permease component
L6451_RS03145	COG0745	RESPONSE REGULATOR receiver
L6451_RS03150	COG5002	protein histidine kinase activity
L6451_RS03170	COG4990	cell redox homeostasis
L6451_RS03180	COG0697	spore germination
L6451_RS03185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS03195	COG5002	protein histidine kinase activity
L6451_RS03200	COG0745	RESPONSE REGULATOR receiver
L6451_RS03205	COG0454	-acetyltransferase
L6451_RS03205	COG0456	acetyltransferase
L6451_RS03210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L6451_RS03215	COG3383	formate dehydrogenase (NAD+) activity
L6451_RS03220	COG2427	Protein of unknown function (DUF1641)
L6451_RS03235	COG0531	amino acid
L6451_RS03240	COG0640	Transcriptional regulator
L6451_RS03245	COG2217	Heavy metal translocating P-type atpase
L6451_RS03250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L6451_RS03265	COG3227	Zinc metalloprotease (Elastase)
L6451_RS03285	COG2720	vancomycin resistance protein
L6451_RS03290	COG1316	TRANSCRIPTIONal
L6451_RS03295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS03300	COG0346	lactoylglutathione lyase activity
L6451_RS03305	COG1253	flavin adenine dinucleotide binding
L6451_RS03310	COG1027	Aspartate ammonia-lyase
L6451_RS03315	COG1620	l-lactate permease
L6451_RS03330	COG3104	oligopeptide transport
L6451_RS03335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6451_RS03340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS03345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS03355	COG2226	methyltransferase
L6451_RS03360	COG0156	8-amino-7-oxononanoate synthase activity
L6451_RS03365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L6451_RS03370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L6451_RS03380	COG4548	von Willebrand factor, type A
L6451_RS03385	COG0714	Associated with various cellular activities
L6451_RS03390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6451_RS03405	COG0531	amino acid
L6451_RS03410	COG2188	Transcriptional regulator
L6451_RS03415	COG1263	PTS System
L6451_RS03415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS03420	COG0366	Alpha amylase catalytic
L6451_RS03435	COG0697	spore germination
L6451_RS03445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6451_RS03450	COG1115	amino acid carrier protein
L6451_RS03455	COG1126	abc transporter atp-binding protein
L6451_RS03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6451_RS03465	COG0765	amino acid transport
L6451_RS03470	COG0765	amino acid transport
L6451_RS03475	COG0833	amino acid
L6451_RS03500	COG2378	regulation of single-species biofilm formation
L6451_RS03505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L6451_RS03510	COG5002	protein histidine kinase activity
L6451_RS03525	COG0659	secondary active sulfate transmembrane transporter activity
L6451_RS03540	COG4166	transmembrane transport
L6451_RS03550	COG0601	transmembrane transport
L6451_RS03555	COG4608	Belongs to the ABC transporter superfamily
L6451_RS03565	COG2271	Major facilitator Superfamily
L6451_RS03570	COG1846	Transcriptional regulator
L6451_RS03575	COG0477	Major facilitator Superfamily
L6451_RS03580	COG1609	Transcriptional regulator
L6451_RS03585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L6451_RS03600	COG1172	Belongs to the binding-protein-dependent transport system permease family
L6451_RS03605	COG1879	ABC-type sugar transport system periplasmic component
L6451_RS03630	COG1063	alcohol dehydrogenase
L6451_RS03645	COG3568	Endonuclease Exonuclease Phosphatase
L6451_RS03675	COG0840	transmembrane signaling receptor activity
L6451_RS03680	COG3584	3D domain protein
L6451_RS03680	COG1388	LysM domain
L6451_RS03685	COG1476	TRANSCRIPTIONal
L6451_RS03700	COG3104	oligopeptide transport
L6451_RS03705	COG1114	Component of the transport system for branched-chain amino acids
L6451_RS03710	COG1464	Belongs to the NlpA lipoprotein family
L6451_RS03715	COG1960	acyl-CoA dehydrogenase activity
L6451_RS03720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L6451_RS03725	COG2011	ABC-type metal ion transport system permease component
L6451_RS03740	COG1113	amino acid transport
L6451_RS03745	COG2252	PERMEase
L6451_RS03760	COG2153	protein acetylation
L6451_RS03770	COG0475	glutathione-regulated potassium exporter activity
L6451_RS03770	COG0569	domain protein
L6451_RS03785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L6451_RS03790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L6451_RS03795	COG4990	cell redox homeostasis
L6451_RS03810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6451_RS03815	COG0697	spore germination
L6451_RS03820	COG0531	amino acid
L6451_RS03830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6451_RS03835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6451_RS03840	COG1918	ferrous iron import across plasma membrane
L6451_RS03840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6451_RS03845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L6451_RS03850	COG0573	inorganic phosphate transmembrane transporter activity
L6451_RS03855	COG0581	inorganic phosphate transmembrane transporter activity
L6451_RS03860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L6451_RS03980	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
L6451_RS04000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L6451_RS04005	COG1116	anion transmembrane transporter activity
L6451_RS04010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6451_RS04015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6451_RS04020	COG0352	thiamine-phosphate diphosphorylase activity
L6451_RS04025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6451_RS04030	COG2104	thiamine diphosphate biosynthetic process
L6451_RS04040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6451_RS04045	COG0351	phosphomethylpyrimidine kinase
L6451_RS04085	COG2205	protein histidine kinase activity
L6451_RS04090	COG2814	Major facilitator Superfamily
L6451_RS04095	COG1846	Transcriptional regulator
L6451_RS04115	COG1136	(ABC) transporter
L6451_RS04125	COG2252	PERMEase
L6451_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS04150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6451_RS04190	COG0778	Nitroreductase
L6451_RS04195	COG2719	SpoVR family
L6451_RS04205	COG3591	Belongs to the peptidase S1B family
L6451_RS04215	COG0446	pyridine nucleotide-disulphide oxidoreductase
L6451_RS04220	COG1937	Protein conserved in bacteria
L6451_RS04225	COG0425	Belongs to the sulfur carrier protein TusA family
L6451_RS04225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6451_RS04230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS04230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6451_RS04235	COG0425	Belongs to the sulfur carrier protein TusA family
L6451_RS04240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6451_RS04250	COG2210	Belongs to the sulfur carrier protein TusA family
L6451_RS04255	COG0730	response to heat
L6451_RS04265	COG1316	TRANSCRIPTIONal
L6451_RS04270	COG0604	alcohol dehydrogenase
L6451_RS04275	COG1283	sodium-dependent phosphate transmembrane transporter activity
L6451_RS04290	COG3711	transcriptional antiterminator
L6451_RS04290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6451_RS04295	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6451_RS04300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6451_RS04320	COG3584	3D domain protein
L6451_RS04320	COG1388	LysM domain
L6451_RS04325	COG0577	efflux transmembrane transporter activity
L6451_RS04330	COG1136	(ABC) transporter
L6451_RS04340	COG5522	Integral membrane protein (intg_mem_TP0381)
L6451_RS04355	COG0577	efflux transmembrane transporter activity
L6451_RS04360	COG1114	Component of the transport system for branched-chain amino acids
L6451_RS04365	COG3546	catalase activity
L6451_RS04400	COG0586	Pfam SNARE associated Golgi protein
L6451_RS04435	COG0531	amino acid
L6451_RS04440	COG0475	glutathione-regulated potassium exporter activity
L6451_RS04450	COG1737	Transcriptional regulator
L6451_RS04460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS04460	COG1263	PTS System
L6451_RS04470	COG2259	Doxx family
L6451_RS04485	COG1522	sequence-specific DNA binding
L6451_RS04500	COG2076	Multidrug Resistance protein
L6451_RS04505	COG1309	transcriptional regulator
L6451_RS04510	COG2814	Major facilitator Superfamily
L6451_RS04515	COG0657	acetylesterase activity
L6451_RS04520	COG1309	transcriptional regulator
L6451_RS04525	COG2124	cytochrome p450
L6451_RS04535	COG1063	alcohol dehydrogenase
L6451_RS04540	COG4533	DNA binding
L6451_RS04545	COG2211	Major facilitator Superfamily
L6451_RS04555	COG0693	protein deglycase activity
L6451_RS04560	COG0753	catalase activity
L6451_RS04570	COG0531	amino acid
L6451_RS04575	COG1012	belongs to the aldehyde dehydrogenase family
L6451_RS04580	COG1132	(ABC) transporter
L6451_RS04585	COG1132	(ABC) transporter
L6451_RS04590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6451_RS04595	COG0765	amino acid transport
L6451_RS04600	COG1126	abc transporter atp-binding protein
L6451_RS04615	COG0189	ligase activity
L6451_RS04645	COG0028	Belongs to the TPP enzyme family
L6451_RS04650	COG3527	Alpha-acetolactate decarboxylase
L6451_RS04660	COG0561	phosphatase activity
L6451_RS04665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L6451_RS04680	COG0659	secondary active sulfate transmembrane transporter activity
L6451_RS04700	COG2244	polysaccharide biosynthetic process
L6451_RS04715	COG4193	domain, Protein
L6451_RS04715	COG5263	repeat protein
L6451_RS04730	COG1024	Enoyl-CoA hydratase
L6451_RS04750	COG1363	Peptidase, m42
L6451_RS04880	COG1649	PFAM Uncharacterised BCR, COG1649
L6451_RS04915	COG0601	transmembrane transport
L6451_RS04920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6451_RS04925	COG0444	Belongs to the ABC transporter superfamily
L6451_RS04930	COG4608	Belongs to the ABC transporter superfamily
L6451_RS04960	COG0477	Major facilitator Superfamily
L6451_RS04965	COG3290	protein histidine kinase activity
L6451_RS04970	COG4565	transcriptional regulatory protein
L6451_RS04975	COG3181	Tripartite tricarboxylate transporter family receptor
L6451_RS04990	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L6451_RS05025	COG0789	Transcriptional regulator
L6451_RS05025	COG4978	Transcriptional regulator
L6451_RS05070	COG0305	Participates in initiation and elongation during chromosome replication
L6451_RS05120	COG0477	Major facilitator Superfamily
L6451_RS05195	COG1404	Belongs to the peptidase S8 family
L6451_RS05260	COG3711	transcriptional antiterminator
L6451_RS05265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS05265	COG1263	PTS System
L6451_RS05265	COG2190	(PTS) system
L6451_RS05270	COG2723	6-phospho-beta-galactosidase activity
L6451_RS05290	COG0367	asparagine synthase
L6451_RS05305	COG1132	(ABC) transporter
L6451_RS05315	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L6451_RS05315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L6451_RS05355	COG0577	efflux transmembrane transporter activity
L6451_RS05355	COG1136	(ABC) transporter
L6451_RS05375	COG1183	phosphatidylcholine synthase activity
L6451_RS05390	COG2376	Dihydroxyacetone kinase
L6451_RS05400	COG2376	Dihydroxyacetone kinase
L6451_RS05495	COG3237	CsbD-like
L6451_RS05520	COG1191	sigma factor activity
L6451_RS05530	COG2208	phosphoserine phosphatase activity
L6451_RS05535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L6451_RS05540	COG0784	Response regulator, receiver
L6451_RS05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6451_RS05540	COG2198	Histidine kinase
L6451_RS05540	COG2205	protein histidine kinase activity
L6451_RS05575	COG0745	RESPONSE REGULATOR receiver
L6451_RS05580	COG2205	protein histidine kinase activity
L6451_RS05620	COG0420	3'-5' exonuclease activity
L6451_RS05625	COG4717	serine-type aminopeptidase activity
L6451_RS05640	COG0346	lactoylglutathione lyase activity
L6451_RS05645	COG0346	lactoylglutathione lyase activity
L6451_RS05650	COG0457	Tetratricopeptide repeat
L6451_RS05660	COG2267	carboxylic ester hydrolase activity
L6451_RS05690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L6451_RS05695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L6451_RS05705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L6451_RS05750	COG0477	Major facilitator Superfamily
L6451_RS05755	COG0477	Major facilitator Superfamily
L6451_RS05765	COG3973	AAA domain
L6451_RS05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6451_RS05790	COG4980	gas vesicle protein
L6451_RS05795	COG0537	adenosine 5'-monophosphoramidase activity
L6451_RS05800	COG1131	(ABC) transporter
L6451_RS05805	COG4473	ABC transporter
L6451_RS05820	COG1309	transcriptional regulator
L6451_RS05830	COG3402	PFAM membrane-flanked domain
L6451_RS05835	COG3428	Bacterial PH domain
L6451_RS05865	COG3402	PFAM membrane-flanked domain
L6451_RS05870	COG3428	Bacterial PH domain
L6451_RS05875	COG2329	Antibiotic biosynthesis monooxygenase
L6451_RS05880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6451_RS05895	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L6451_RS05920	COG1309	transcriptional regulator
L6451_RS05925	COG1511	domain protein
L6451_RS05955	COG2378	regulation of single-species biofilm formation
L6451_RS05960	COG1609	Transcriptional regulator
L6451_RS05970	COG1234	tRNA 3'-trailer cleavage
L6451_RS05975	COG0095	Lipoate-protein ligase
L6451_RS05985	COG2205	protein histidine kinase activity
L6451_RS05990	COG0745	RESPONSE REGULATOR receiver
L6451_RS06015	COG0501	Belongs to the peptidase M48B family
L6451_RS06020	COG0697	spore germination
L6451_RS06040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L6451_RS06045	COG2224	Isocitrate lyase
L6451_RS06055	COG1278	Cold shock
L6451_RS06070	COG4903	ComK protein
L6451_RS06080	COG4585	Histidine kinase
L6451_RS06085	COG2197	response regulator
L6451_RS06095	COG0398	Pfam SNARE associated Golgi protein
L6451_RS06170	COG0179	Fumarylacetoacetate (FAA) hydrolase
L6451_RS06195	COG0367	asparagine synthase
L6451_RS06200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L6451_RS06205	COG0753	catalase activity
L6451_RS06215	COG0004	ammonium transporteR
L6451_RS06235	COG2996	Protein conserved in bacteria
L6451_RS06240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6451_RS06250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS06265	COG0561	phosphatase activity
L6451_RS06275	COG0542	response to heat
L6451_RS06285	COG2267	carboxylic ester hydrolase activity
L6451_RS06300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6451_RS06305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L6451_RS06310	COG5504	Zn-dependent protease
L6451_RS06320	COG0180	Tryptophanyl-tRNA synthetase
L6451_RS06330	COG4166	transmembrane transport
L6451_RS06335	COG0601	transmembrane transport
L6451_RS06340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6451_RS06345	COG0444	Belongs to the ABC transporter superfamily
L6451_RS06350	COG4608	Belongs to the ABC transporter superfamily
L6451_RS06355	COG0534	Mate efflux family protein
L6451_RS06360	COG4166	transmembrane transport
L6451_RS06375	COG0861	Integral membrane protein TerC family
L6451_RS06380	COG4862	establishment of competence for transformation
L6451_RS06385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6451_RS06395	COG1164	Oligoendopeptidase f
L6451_RS06410	COG2346	COG2346, Truncated hemoglobins
L6451_RS06415	COG4116	CYTH
L6451_RS06425	COG2357	RelA SpoT domain protein
L6451_RS06435	COG0564	pseudouridine synthase activity
L6451_RS06450	COG0772	Belongs to the SEDS family
L6451_RS06455	COG1216	Glycosyl transferase, family 2
L6451_RS06475	COG0457	Tetratricopeptide repeat
L6451_RS06475	COG0463	Glycosyl transferase, family 2
L6451_RS06495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L6451_RS06510	COG1091	dTDP-4-dehydrorhamnose reductase activity
L6451_RS06555	COG2153	protein acetylation
L6451_RS06565	COG2382	esterase
L6451_RS06580	COG5492	domain, Protein
L6451_RS06585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6451_RS06595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L6451_RS06595	COG0512	Glutamine amidotransferase of anthranilate synthase
L6451_RS06630	COG1620	l-lactate permease
L6451_RS06635	COG5634	Uncharacterized conserved protein (DUF2278)
L6451_RS06700	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6451_RS06710	COG1476	TRANSCRIPTIONal
L6451_RS06755	COG2226	methyltransferase
L6451_RS06765	COG1686	Belongs to the peptidase S11 family
L6451_RS06770	COG0681	Belongs to the peptidase S26 family
L6451_RS06790	COG1396	sequence-specific DNA binding
L6451_RS06805	COG1012	belongs to the aldehyde dehydrogenase family
L6451_RS06815	COG1176	ABC-type spermidine putrescine transport system, permease component I
L6451_RS06820	COG1177	transmembrane transport
L6451_RS06825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
L6451_RS06835	COG2409	Drug exporters of the RND superfamily
L6451_RS06845	COG0564	pseudouridine synthase activity
L6451_RS06855	COG2340	Cysteine-rich secretory protein family
L6451_RS06860	COG0247	lactate metabolic process
L6451_RS06865	COG0277	FAD linked oxidase domain protein
L6451_RS06870	COG3835	regulator
L6451_RS06880	COG0745	RESPONSE REGULATOR receiver
L6451_RS06885	COG5002	protein histidine kinase activity
L6451_RS06890	COG2186	Transcriptional regulator
L6451_RS06910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L6451_RS06920	COG2116	formate transmembrane transporter activity
L6451_RS06925	COG0861	Integral membrane protein TerC family
L6451_RS06930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6451_RS06940	COG2030	dehydratase
L6451_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS06965	COG3243	poly(R)-hydroxyalkanoic acid synthase
L6451_RS06970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6451_RS06975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6451_RS06995	COG1840	ABC-type Fe3 transport system, periplasmic component
L6451_RS07000	COG3842	ATPase activity
L6451_RS07025	COG1349	DNA-binding transcription factor activity
L6451_RS07035	COG0235	Class ii aldolase
L6451_RS07045	COG2861	carbohydrate metabolic process
L6451_RS07055	COG3852	Histidine kinase
L6451_RS07070	COG2318	DinB family
L6451_RS07080	COG5002	protein histidine kinase activity
L6451_RS07090	COG0720	synthase
L6451_RS07105	COG4873	Protein conserved in bacteria
L6451_RS07135	COG1780	Probably involved in ribonucleotide reductase function
L6451_RS07145	COG1403	HNH endonuclease
L6451_RS07155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L6451_RS07160	COG1725	Transcriptional regulator
L6451_RS07165	COG1131	(ABC) transporter
L6451_RS07175	COG1131	(ABC) transporter
L6451_RS07180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6451_RS07195	COG1522	sequence-specific DNA binding
L6451_RS07205	COG1335	isochorismatase
L6451_RS07215	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6451_RS07220	COG2070	2-Nitropropane dioxygenase
L6451_RS07225	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L6451_RS07235	COG1696	Membrane protein involved in D-alanine export
L6451_RS07260	COG0716	FMN binding
L6451_RS07275	COG3173	Aminoglycoside phosphotransferase
L6451_RS07295	COG0534	Mate efflux family protein
L6451_RS07300	COG1968	undecaprenyl-diphosphatase activity
L6451_RS07315	COG1846	Transcriptional regulator
L6451_RS07325	COG1301	dicarboxylic acid transport
L6451_RS07330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6451_RS07335	COG4709	membrane
L6451_RS07340	COG3874	Sporulation protein YtfJ
L6451_RS07360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6451_RS07365	COG0028	Belongs to the TPP enzyme family
L6451_RS07370	COG0440	acetolactate synthase activity
L6451_RS07445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L6451_RS07460	COG1183	phosphatidylcholine synthase activity
L6451_RS07465	COG1368	sulfuric ester hydrolase activity
L6451_RS07475	COG0019	diaminopimelate decarboxylase activity
L6451_RS07495	COG0529	Catalyzes the synthesis of activated sulfate
L6451_RS07500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L6451_RS07520	COG1648	precorrin-2 dehydrogenase activity
L6451_RS07525	COG0733	neurotransmitter:sodium symporter activity
L6451_RS07545	COG1757	Na H antiporter
L6451_RS07560	COG4758	membrane
L6451_RS07565	COG4585	Histidine kinase
L6451_RS07570	COG2197	response regulator
L6451_RS07580	COG1114	Component of the transport system for branched-chain amino acids
L6451_RS07590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L6451_RS07630	COG0730	response to heat
L6451_RS07635	COG0306	phosphate transporter
L6451_RS07640	COG1392	Phosphate transport regulator
L6451_RS07645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6451_RS07660	COG3852	Histidine kinase
L6451_RS07665	COG1801	Protein of unknown function DUF72
L6451_RS07680	COG0582	viral genome integration into host DNA
L6451_RS07685	COG5002	protein histidine kinase activity
L6451_RS07705	COG0392	lysyltransferase activity
L6451_RS07705	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L6451_RS07720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6451_RS07725	COG1686	Belongs to the peptidase S11 family
L6451_RS07730	COG2715	membrane protein required for spore maturation
L6451_RS07735	COG0700	Nucleoside recognition
L6451_RS07740	COG1187	pseudouridine synthase activity
L6451_RS07750	COG1333	cytochrome c biogenesis protein
L6451_RS07755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L6451_RS07760	COG0745	RESPONSE REGULATOR receiver
L6451_RS07765	COG5002	protein histidine kinase activity
L6451_RS07770	COG2096	Adenosyltransferase
L6451_RS07775	COG4942	peptidase
L6451_RS07785	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L6451_RS07790	COG1141	Ferredoxin
L6451_RS07800	COG0514	ATP-dependent DNA helicase (RecQ)
L6451_RS07805	COG1266	CAAX protease self-immunity
L6451_RS07815	COG1408	metallophosphoesterase
L6451_RS07825	COG4862	establishment of competence for transformation
L6451_RS07830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L6451_RS07850	COG0492	ferredoxin-NADP+ reductase activity
L6451_RS07855	COG0252	asparaginase activity
L6451_RS07925	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6451_RS07940	COG0142	geranyltranstransferase activity
L6451_RS07950	COG0142	geranyltranstransferase activity
L6451_RS07975	COG0457	Tetratricopeptide repeat
L6451_RS07995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L6451_RS08005	COG4347	Protein of unknown function (DUF1405)
L6451_RS08020	COG2738	Putative neutral zinc metallopeptidase
L6451_RS08030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS08035	COG1694	Mazg nucleotide pyrophosphohydrolase
L6451_RS08050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L6451_RS08055	COG0438	transferase activity, transferring glycosyl groups
L6451_RS08090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L6451_RS08090	COG1199	ATP-dependent helicase activity
L6451_RS08110	COG3935	DnaD domain protein
L6451_RS08115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L6451_RS08125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6451_RS08125	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6451_RS08185	COG0116	Belongs to the methyltransferase superfamily
L6451_RS08195	COG1199	ATP-dependent helicase activity
L6451_RS08200	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L6451_RS08210	COG3173	Aminoglycoside phosphotransferase
L6451_RS08215	COG0024	Methionine aminopeptidase
L6451_RS08225	COG2233	PERMEase
L6451_RS08230	COG2311	Membrane
L6451_RS08235	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6451_RS08245	COG0456	acetyltransferase
L6451_RS08285	COG0754	glutathionylspermidine amidase activity
L6451_RS08300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6451_RS08315	COG0454	-acetyltransferase
L6451_RS08335	COG0328	RNA-DNA hybrid ribonuclease activity
L6451_RS08370	COG3403	YqcI/YcgG family
L6451_RS08375	COG1280	lysine exporter protein (LysE YggA)
L6451_RS08390	COG3162	membrane
L6451_RS08395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6451_RS08400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6451_RS08410	COG0475	glutathione-regulated potassium exporter activity
L6451_RS08415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6451_RS08420	COG4978	Transcriptional regulator
L6451_RS08420	COG0789	Transcriptional regulator
L6451_RS08430	COG2323	membrane
L6451_RS08435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L6451_RS08470	COG2814	Major facilitator Superfamily
L6451_RS08500	COG1923	regulation of RNA biosynthetic process
L6451_RS08510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L6451_RS08515	COG1360	Flagellar Motor Protein
L6451_RS08520	COG2201	protein-glutamate methylesterase activity
L6451_RS08525	COG0643	Histidine kinase
L6451_RS08525	COG2198	Histidine kinase
L6451_RS08530	COG1776	CheC inhibitor of MCP methylation
L6451_RS08530	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6451_RS08545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L6451_RS08565	COG1256	bacterial-type flagellum assembly
L6451_RS08570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L6451_RS08575	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
L6451_RS08590	COG1815	bacterial-type flagellum-dependent cell motility
L6451_RS08595	COG1558	bacterial-type flagellum-dependent cell motility
L6451_RS08605	COG1766	The M ring may be actively involved in energy transduction
L6451_RS08610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6451_RS08620	COG1157	protein secretion by the type III secretion system
L6451_RS08655	COG0784	Response regulator, receiver
L6451_RS08655	COG0835	chemotaxis
L6451_RS08665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L6451_RS08675	COG0741	lytic transglycosylase activity
L6451_RS08685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6451_RS08690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6451_RS08690	COG1776	CheC inhibitor of MCP methylation
L6451_RS08700	COG1338	Plays a role in the flagellum-specific transport system
L6451_RS08705	COG1987	bacterial-type flagellum assembly
L6451_RS08715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L6451_RS08720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L6451_RS08725	COG1419	protein localization to endoplasmic reticulum
L6451_RS08730	COG4786	Flagellar basal body rod
L6451_RS08735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L6451_RS08760	COG1309	transcriptional regulator
L6451_RS08780	COG2329	Antibiotic biosynthesis monooxygenase
L6451_RS08795	COG3764	Sortase (surface protein transpeptidase)
L6451_RS08800	COG3764	Sortase (surface protein transpeptidase)
L6451_RS08825	COG0583	DNA-binding transcription factor activity
L6451_RS08830	COG3842	ATPase activity
L6451_RS08835	COG0725	ABC transporter, periplasmic molybdate-binding protein
L6451_RS08845	COG1234	tRNA 3'-trailer cleavage
L6451_RS08860	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS08875	COG0406	alpha-ribazole phosphatase activity
L6451_RS08895	COG1846	Transcriptional regulator
L6451_RS08905	COG0367	asparagine synthase
L6451_RS08935	COG1802	Transcriptional regulator
L6451_RS08940	COG0697	spore germination
L6451_RS08945	COG0523	cobalamin synthesis protein
L6451_RS08950	COG0701	Predicted permease
L6451_RS08965	COG1757	Na H antiporter
L6451_RS08970	COG0114	fumarate hydratase activity
L6451_RS08985	COG0534	Mate efflux family protein
L6451_RS08990	COG3340	Belongs to the peptidase S51 family
L6451_RS09010	COG0785	Cytochrome C biogenesis protein
L6451_RS09045	COG2733	membrane
L6451_RS09080	COG1131	(ABC) transporter
L6451_RS09095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6451_RS09120	COG0528	UMP kinase activity
L6451_RS09130	COG1027	Aspartate ammonia-lyase
L6451_RS09135	COG0281	malic enzyme
L6451_RS09140	COG4191	Histidine kinase
L6451_RS09145	COG0784	Response regulator, receiver
L6451_RS09155	COG1361	Conserved repeat domain
L6451_RS09260	COG2814	Major facilitator Superfamily
L6451_RS09275	COG1966	Carbon starvation protein
L6451_RS09285	COG1695	Transcriptional regulator
L6451_RS09295	COG0477	Major facilitator Superfamily
L6451_RS09300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6451_RS09305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L6451_RS09310	COG4166	transmembrane transport
L6451_RS09315	COG2223	nitrite transmembrane transporter activity
L6451_RS09320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6451_RS09335	COG2244	polysaccharide biosynthetic process
L6451_RS09340	COG0733	neurotransmitter:sodium symporter activity
L6451_RS09350	COG5566	PFAM Mor transcription activator
L6451_RS09355	COG2323	membrane
L6451_RS09370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6451_RS09380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6451_RS09385	COG0028	Belongs to the TPP enzyme family
L6451_RS09395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
L6451_RS09405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L6451_RS09430	COG2814	Major facilitator Superfamily
L6451_RS09435	COG3384	dioxygenase
L6451_RS09445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L6451_RS09455	COG0427	acetyl-CoA hydrolase
L6451_RS09475	COG1073	alpha beta
L6451_RS09480	COG4166	transmembrane transport
L6451_RS09505	COG0535	radical SAM domain protein
L6451_RS09510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS09535	COG1914	H( )-stimulated, divalent metal cation uptake system
L6451_RS09550	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L6451_RS09555	COG0531	amino acid
L6451_RS09590	COG0714	Associated with various cellular activities
L6451_RS09600	COG3552	Protein containing von Willebrand factor type A (VWA) domain
L6451_RS09625	COG2390	Transcriptional regulator
L6451_RS09635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS09640	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L6451_RS09670	COG0006	proline dipeptidase activity
L6451_RS09675	COG2132	Multicopper oxidase
L6451_RS09690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L6451_RS09720	COG1114	Component of the transport system for branched-chain amino acids
L6451_RS09730	COG1276	copper resistance
L6451_RS09730	COG2372	response to copper ion
L6451_RS09735	COG4549	nuclear export factor GLE1
L6451_RS09745	COG0697	spore germination
L6451_RS09750	COG0583	DNA-binding transcription factor activity
L6451_RS09755	COG1959	2 iron, 2 sulfur cluster binding
L6451_RS09760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L6451_RS09765	COG0778	Nitroreductase
L6451_RS09775	COG0628	permease
L6451_RS09785	COG1231	oxidoreductase activity
L6451_RS09790	COG0523	cobalamin synthesis protein
L6451_RS09800	COG0318	PFAM AMP-dependent synthetase and ligase
L6451_RS09805	COG2030	dehydratase
L6451_RS09810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6451_RS09820	COG0411	ABC transporter
L6451_RS09840	COG0583	DNA-binding transcription factor activity
L6451_RS09870	COG1271	oxidase subunit
L6451_RS09875	COG1294	oxidase, subunit
L6451_RS09880	COG4988	ABC transporter
L6451_RS09885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L6451_RS09905	COG1686	Belongs to the peptidase S11 family
L6451_RS09920	COG0791	NLP P60 protein
L6451_RS09920	COG1388	LysM domain
L6451_RS09930	COG1132	(ABC) transporter
L6451_RS09935	COG0745	RESPONSE REGULATOR receiver
L6451_RS09940	COG5002	protein histidine kinase activity
L6451_RS09945	COG2205	protein histidine kinase activity
L6451_RS09950	COG0745	RESPONSE REGULATOR receiver
L6451_RS09975	COG0300	oxidoreductase activity
L6451_RS09980	COG4122	O-methyltransferase activity
L6451_RS09995	COG5658	integral membrane protein
L6451_RS10010	COG0460	homoserine dehydrogenase
L6451_RS10035	COG1316	TRANSCRIPTIONal
L6451_RS10045	COG0745	RESPONSE REGULATOR receiver
L6451_RS10050	COG5002	protein histidine kinase activity
L6451_RS10065	COG1285	pathogenesis
L6451_RS10070	COG1247	-acetyltransferase
L6451_RS10090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6451_RS10100	COG1082	Xylose isomerase domain protein TIM barrel
L6451_RS10110	COG2814	Major facilitator Superfamily
L6451_RS10115	COG1279	arginine transmembrane transporter activity
L6451_RS10125	COG1752	Esterase of the alpha-beta hydrolase superfamily
L6451_RS10160	COG0577	efflux transmembrane transporter activity
L6451_RS10165	COG2002	toxin-antitoxin pair type II binding
L6451_RS10170	COG1404	Belongs to the peptidase S8 family
L6451_RS10175	COG0640	Transcriptional regulator
L6451_RS10180	COG0667	Aldo Keto reductase
L6451_RS10185	COG2814	Major facilitator Superfamily
L6451_RS10210	COG0840	transmembrane signaling receptor activity
L6451_RS10225	COG3949	Membrane
L6451_RS10230	COG0783	Belongs to the Dps family
L6451_RS10245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6451_RS10255	COG1231	oxidoreductase activity
L6451_RS10265	COG4989	oxidoreductase activity
L6451_RS10270	COG0523	cobalamin synthesis protein
L6451_RS10275	COG0456	acetyltransferase
L6451_RS10280	COG3443	Belongs to the bacterial solute-binding protein 9 family
L6451_RS10280	COG0803	Belongs to the bacterial solute-binding protein 9 family
L6451_RS10290	COG0702	epimerase
L6451_RS10300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L6451_RS10310	COG4166	transmembrane transport
L6451_RS10325	COG0406	alpha-ribazole phosphatase activity
L6451_RS10335	COG5337	Spore coat protein CotH
L6451_RS10340	COG1051	belongs to the nudix hydrolase family
L6451_RS10345	COG0586	Pfam SNARE associated Golgi protein
L6451_RS10350	COG2244	polysaccharide biosynthetic process
L6451_RS10360	COG0701	Predicted permease
L6451_RS10365	COG3689	TIGRFAM TIGR03943 family protein
L6451_RS10370	COG1607	acyl-coa hydrolase
L6451_RS10380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6451_RS10395	COG0702	epimerase
L6451_RS10400	COG2839	Protein conserved in bacteria
L6451_RS10405	COG1253	flavin adenine dinucleotide binding
L6451_RS10420	COG1114	Component of the transport system for branched-chain amino acids
L6451_RS10425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6451_RS10445	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6451_RS10455	COG1876	peptidase activity
L6451_RS10465	COG0154	amidase activity
L6451_RS10470	COG2211	Major facilitator Superfamily
L6451_RS10485	COG2368	4-hydroxyphenylacetate
L6451_RS10495	COG0196	riboflavin kinase activity
L6451_RS10510	COG0251	oxidation-reduction process
L6451_RS10520	COG3971	2-oxopent-4-enoate hydratase activity
L6451_RS10540	COG1942	4-Oxalocrotonate Tautomerase
L6451_RS10560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L6451_RS10565	COG4106	trans-aconitate 2-methyltransferase activity
L6451_RS10580	COG1819	glycosyl
L6451_RS10585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS10590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS10620	COG0456	acetyltransferase
L6451_RS10660	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6451_RS10760	COG3874	Sporulation protein YtfJ
L6451_RS10785	COG2226	methyltransferase
L6451_RS10810	COG0346	lactoylglutathione lyase activity
L6451_RS10820	COG0604	alcohol dehydrogenase
L6451_RS10825	COG1595	DNA-templated transcription, initiation
L6451_RS10855	COG0386	Belongs to the glutathione peroxidase family
L6451_RS10860	COG1305	Transglutaminase-like
L6451_RS10865	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L6451_RS10870	COG0714	Associated with various cellular activities
L6451_RS10885	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
L6451_RS10890	COG1140	nitrate reductase beta subunit
L6451_RS10895	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L6451_RS10900	COG2181	nitrate reductase activity
L6451_RS10905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L6451_RS10910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L6451_RS10915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6451_RS10920	COG0303	'Molybdopterin
L6451_RS10925	COG0314	molybdopterin synthase activity
L6451_RS10935	COG2223	nitrite transmembrane transporter activity
L6451_RS10945	COG1648	precorrin-2 dehydrogenase activity
L6451_RS10955	COG1587	Uroporphyrinogen-III synthase
L6451_RS10955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L6451_RS10960	COG2146	nitrite reductase [NAD(P)H] activity
L6451_RS10965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L6451_RS10970	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L6451_RS11005	COG2359	stage V sporulation protein S
L6451_RS11030	COG1418	mRNA catabolic process
L6451_RS11035	COG0488	(ABC) transporter
L6451_RS11050	COG0629	single-stranded DNA binding
L6451_RS11065	COG1413	lyase activity
L6451_RS11080	COG2136	Putative SAM-dependent methyltransferase
L6451_RS11080	COG2521	methyltransferase
L6451_RS11130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L6451_RS11135	COG0017	Asparaginyl-tRNA synthetase
L6451_RS11140	COG1929	Belongs to the glycerate kinase type-1 family
L6451_RS11145	COG0471	metal ion transport
L6451_RS11150	COG0745	RESPONSE REGULATOR receiver
L6451_RS11170	COG0733	neurotransmitter:sodium symporter activity
L6451_RS11195	COG2610	gluconate transmembrane transporter activity
L6451_RS11200	COG1454	alcohol dehydrogenase
L6451_RS11205	COG1794	racemase activity, acting on amino acids and derivatives
L6451_RS11215	COG0456	acetyltransferase
L6451_RS11220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L6451_RS11230	COG1131	(ABC) transporter
L6451_RS11235	COG4473	ABC transporter
L6451_RS11245	COG0546	phosphoglycolate phosphatase activity
L6451_RS11265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6451_RS11270	COG3250	beta-galactosidase activity
L6451_RS11285	COG0768	penicillin binding
L6451_RS11295	COG0204	Acyl-transferase
L6451_RS11300	COG1272	protein, Hemolysin III
L6451_RS11310	COG0805	protein transport
L6451_RS11320	COG1307	EDD domain protein, DegV family
L6451_RS11330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L6451_RS11335	COG1999	signal sequence binding
L6451_RS11340	COG0071	Belongs to the small heat shock protein (HSP20) family
L6451_RS11345	COG0367	asparagine synthase
L6451_RS11365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6451_RS11370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6451_RS11390	COG1335	isochorismatase
L6451_RS11395	COG0071	Belongs to the small heat shock protein (HSP20) family
L6451_RS11400	COG0668	transmembrane transport
L6451_RS11405	COG4585	Histidine kinase
L6451_RS11405	COG2203	Gaf domain
L6451_RS11410	COG2197	response regulator
L6451_RS11420	COG1064	alcohol dehydrogenase
L6451_RS11475	COG0517	IMP dehydrogenase activity
L6451_RS11475	COG1125	glycine betaine transport
L6451_RS11480	COG1174	glycine betaine transport
L6451_RS11520	COG1253	flavin adenine dinucleotide binding
L6451_RS11525	COG1012	belongs to the aldehyde dehydrogenase family
L6451_RS11530	COG5506	Protein of unknown function (DUF1694)
L6451_RS11545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6451_RS11550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L6451_RS11555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L6451_RS11560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6451_RS11565	COG0456	acetyltransferase
L6451_RS11570	COG3829	transcription factor binding
L6451_RS11575	COG1509	lysine 2,3-aminomutase activity
L6451_RS11610	COG4991	sh3 domain protein
L6451_RS11610	COG3064	Membrane
L6451_RS11610	COG0515	serine threonine protein kinase
L6451_RS11615	COG4326	sporulation control protein
L6451_RS11620	COG0671	phosphoesterase, PA-phosphatase related
L6451_RS11645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6451_RS11645	COG0456	acetyltransferase
L6451_RS11660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L6451_RS11665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6451_RS11715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6451_RS11745	COG0300	oxidoreductase activity
L6451_RS11765	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6451_RS11765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6451_RS11780	COG4841	protein insertion into membrane
L6451_RS11785	COG0372	Belongs to the citrate synthase family
L6451_RS11790	COG2079	MmgE PrpD family protein
L6451_RS11795	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L6451_RS11800	COG1960	acyl-CoA dehydrogenase activity
L6451_RS11805	COG2084	Dehydrogenase
L6451_RS11815	COG1280	lysine exporter protein (LysE YggA)
L6451_RS11820	COG1024	Enoyl-CoA hydratase
L6451_RS11835	COG0420	3'-5' exonuclease activity
L6451_RS11860	COG2223	nitrite transmembrane transporter activity
L6451_RS11865	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS11870	COG1169	isochorismate synthase
L6451_RS11875	COG1021	2,3-dihydroxybenzoate-AMP ligase
L6451_RS11880	COG1535	isochorismatase
L6451_RS11880	COG3433	isochorismatase activity
L6451_RS11885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L6451_RS11890	COG3251	PFAM MbtH domain protein
L6451_RS11895	COG2814	Major facilitator Superfamily
L6451_RS11910	COG0776	regulation of translation
L6451_RS11920	COG2318	DinB family
L6451_RS11930	COG1115	amino acid carrier protein
L6451_RS11945	COG2329	Antibiotic biosynthesis monooxygenase
L6451_RS11950	COG1187	pseudouridine synthase activity
L6451_RS11955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L6451_RS11960	COG1136	(ABC) transporter
L6451_RS11975	COG2814	Major facilitator Superfamily
L6451_RS12035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS12070	COG1247	-acetyltransferase
L6451_RS12100	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L6451_RS12110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS12120	COG1278	Cold shock
L6451_RS12135	COG0010	Belongs to the arginase family
L6451_RS12145	COG1846	Transcriptional regulator
L6451_RS12150	COG2814	Major facilitator Superfamily
L6451_RS12155	COG0583	DNA-binding transcription factor activity
L6451_RS12160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L6451_RS12175	COG0583	DNA-binding transcription factor activity
L6451_RS12180	COG2258	MOSC domain
L6451_RS12195	COG1132	(ABC) transporter
L6451_RS12200	COG1132	(ABC) transporter
L6451_RS12220	COG1396	sequence-specific DNA binding
L6451_RS12250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L6451_RS12260	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
L6451_RS12265	COG1595	DNA-templated transcription, initiation
L6451_RS12290	COG1649	PFAM Uncharacterised BCR, COG1649
L6451_RS12315	COG2971	BadF BadG BcrA BcrD
L6451_RS12325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L6451_RS12345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS12375	COG1309	transcriptional regulator
L6451_RS12390	COG1136	(ABC) transporter
L6451_RS12390	COG0577	efflux transmembrane transporter activity
L6451_RS12440	COG1846	Transcriptional regulator
L6451_RS12470	COG2195	Cleaves the N-terminal amino acid of tripeptides
L6451_RS12480	COG0110	maltose O-acetyltransferase activity
L6451_RS12485	COG1686	Belongs to the peptidase S11 family
L6451_RS12495	COG0768	penicillin binding
L6451_RS12500	COG1595	DNA-templated transcription, initiation
L6451_RS12510	COG0768	penicillin binding
L6451_RS12515	COG0768	penicillin binding
L6451_RS12520	COG2367	Beta-lactamase
L6451_RS12525	COG1408	metallophosphoesterase
L6451_RS12535	COG1131	(ABC) transporter
L6451_RS12545	COG1309	transcriptional regulator
L6451_RS12560	COG1960	acyl-CoA dehydrogenase activity
L6451_RS12565	COG0439	Biotin carboxylase
L6451_RS12570	COG0511	ligase activity, forming carbon-carbon bonds
L6451_RS12575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L6451_RS12580	COG1024	Enoyl-CoA hydratase
L6451_RS12585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L6451_RS12590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6451_RS12600	COG1247	-acetyltransferase
L6451_RS12605	COG0572	uridine kinase
L6451_RS12615	COG1686	Belongs to the peptidase S11 family
L6451_RS12640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L6451_RS12660	COG3227	Zinc metalloprotease (Elastase)
L6451_RS12675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L6451_RS12705	COG2814	Major facilitator Superfamily
L6451_RS12715	COG2226	methyltransferase
L6451_RS12750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS12795	COG3386	PFAM SMP-30 Gluconolaconase
L6451_RS12805	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L6451_RS12810	COG3773	Cell wall hydrolase
L6451_RS12820	COG0745	RESPONSE REGULATOR receiver
L6451_RS12825	COG2205	protein histidine kinase activity
L6451_RS12835	COG0488	(ABC) transporter
L6451_RS12845	COG1136	(ABC) transporter
L6451_RS12850	COG0577	efflux transmembrane transporter activity
L6451_RS12875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS12885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L6451_RS13000	COG2124	cytochrome p450
L6451_RS13035	COG0561	phosphatase activity
L6451_RS13040	COG5002	protein histidine kinase activity
L6451_RS13050	COG1819	glycosyl
L6451_RS13055	COG1794	racemase activity, acting on amino acids and derivatives
L6451_RS13080	COG2205	protein histidine kinase activity
L6451_RS13090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6451_RS13095	COG0604	alcohol dehydrogenase
L6451_RS13100	COG0671	phosphoesterase, PA-phosphatase related
L6451_RS13105	COG0768	penicillin binding
L6451_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS13125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6451_RS13165	COG0693	protein deglycase activity
L6451_RS13190	COG2814	Major facilitator Superfamily
L6451_RS13205	COG0584	glycerophosphoryl diester phosphodiesterase
L6451_RS13225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS13230	COG0697	spore germination
L6451_RS13250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6451_RS13260	COG2223	nitrite transmembrane transporter activity
L6451_RS13275	COG2816	NAD+ diphosphatase activity
L6451_RS13280	COG0592	DNA-directed DNA polymerase activity
L6451_RS13285	COG1051	belongs to the nudix hydrolase family
L6451_RS13315	COG3878	Protein conserved in bacteria
L6451_RS13340	COG4667	esterase of the alpha-beta hydrolase superfamily
L6451_RS13365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L6451_RS13380	COG0322	excinuclease ABC activity
L6451_RS13420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6451_RS13445	COG1011	Hydrolase
L6451_RS13465	COG1523	belongs to the glycosyl hydrolase 13 family
L6451_RS13470	COG3227	Zinc metalloprotease (Elastase)
L6451_RS13490	COG0201	protein transport
L6451_RS13500	COG0697	spore germination
L6451_RS13505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS13540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS13555	COG2959	enzyme of heme biosynthesis
L6451_RS13585	COG3844	kynureninase activity
L6451_RS13590	COG1309	transcriptional regulator
L6451_RS13620	COG3284	Transcriptional regulator
L6451_RS13640	COG1349	DNA-binding transcription factor activity
L6451_RS13650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L6451_RS13655	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6451_RS13660	COG0022	dehydrogenase e1 component
L6451_RS13665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6451_RS13675	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS13690	COG1051	belongs to the nudix hydrolase family
L6451_RS13710	COG4176	ABC-type proline glycine betaine transport system permease component
L6451_RS13715	COG4175	Glycine betaine
L6451_RS13715	COG0517	IMP dehydrogenase activity
L6451_RS13740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
L6451_RS13745	COG2153	protein acetylation
L6451_RS13750	COG3397	chitin binding
L6451_RS13765	COG2205	protein histidine kinase activity
L6451_RS13770	COG2226	methyltransferase
L6451_RS13775	COG2315	Protein conserved in bacteria
L6451_RS13780	COG2153	protein acetylation
L6451_RS13835	COG3973	AAA domain
L6451_RS13855	COG0514	ATP-dependent DNA helicase (RecQ)
L6451_RS13875	COG4637	Psort location Cytoplasmic, score
L6451_RS13900	COG3397	chitin binding
L6451_RS13915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L6451_RS13920	COG1115	amino acid carrier protein
L6451_RS13925	COG1012	belongs to the aldehyde dehydrogenase family
L6451_RS13930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L6451_RS13940	COG3938	Belongs to the proline racemase family
L6451_RS13945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6451_RS13985	COG0586	Pfam SNARE associated Golgi protein
L6451_RS14000	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L6451_RS14005	COG0519	Catalyzes the synthesis of GMP from XMP
L6451_RS14010	COG4166	transmembrane transport
L6451_RS14020	COG4948	Mandelate Racemase Muconate Lactonizing
L6451_RS14060	COG2936	dipeptidyl-peptidase activity
L6451_RS14065	COG5002	protein histidine kinase activity
L6451_RS14070	COG0745	RESPONSE REGULATOR receiver
L6451_RS14105	COG1164	Oligoendopeptidase f
L6451_RS14110	COG0531	amino acid
L6451_RS14115	COG1522	sequence-specific DNA binding
L6451_RS14120	COG1307	EDD domain protein, DegV family
L6451_RS14160	COG2814	Major facilitator Superfamily
L6451_RS14170	COG1664	Polymer-forming cytoskeletal
L6451_RS14175	COG0789	Transcriptional regulator
L6451_RS14180	COG4533	DNA binding
L6451_RS14185	COG0477	Major facilitator Superfamily
L6451_RS14185	COG2814	Major facilitator Superfamily
L6451_RS14205	COG2261	transglycosylase associated protein
L6451_RS14220	COG2226	methyltransferase
L6451_RS14255	COG0436	Aminotransferase
L6451_RS14260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L6451_RS14265	COG5146	pantothenate kinase activity
L6451_RS14270	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
L6451_RS14285	COG1131	(ABC) transporter
L6451_RS14335	COG0628	permease
L6451_RS14350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6451_RS14355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6451_RS14360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6451_RS14375	COG2816	NAD+ diphosphatase activity
L6451_RS14395	COG2746	aminoglycoside 3-N-acetyltransferase activity
L6451_RS14420	COG0697	spore germination
L6451_RS14425	COG2318	DinB family
L6451_RS14430	COG0454	-acetyltransferase
L6451_RS14445	COG4912	Dna alkylation repair
L6451_RS14465	COG0861	Integral membrane protein TerC family
L6451_RS14470	COG1368	sulfuric ester hydrolase activity
L6451_RS14475	COG0488	(ABC) transporter
L6451_RS14485	COG1033	growth of symbiont in host cell
L6451_RS14485	COG2409	Drug exporters of the RND superfamily
L6451_RS14490	COG1309	transcriptional regulator
L6451_RS14510	COG0287	Prephenate dehydrogenase
L6451_RS14515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L6451_RS14525	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L6451_RS14525	COG1605	Chorismate mutase
L6451_RS14560	COG3584	3D domain protein
L6451_RS14560	COG1388	LysM domain
L6451_RS14570	COG1595	DNA-templated transcription, initiation
L6451_RS14595	COG1879	ABC-type sugar transport system periplasmic component
L6451_RS14605	COG1172	Belongs to the binding-protein-dependent transport system permease family
L6451_RS14660	COG2390	Transcriptional regulator
L6451_RS14665	COG1070	Carbohydrate kinase
L6451_RS14695	COG2329	Antibiotic biosynthesis monooxygenase
L6451_RS14715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS14730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6451_RS14735	COG4187	Peptidase family M20/M25/M40
L6451_RS14740	COG1414	Transcriptional regulator
L6451_RS14745	COG0833	amino acid
L6451_RS14750	COG1690	Belongs to the RtcB family
L6451_RS14755	COG3239	Fatty acid desaturase
L6451_RS14760	COG1785	Belongs to the alkaline phosphatase family
L6451_RS14770	COG3655	Transcriptional regulator
L6451_RS14785	COG4377	Putative membrane peptidase family (DUF2324)
L6451_RS14795	COG3279	Response regulator of the LytR AlgR family
L6451_RS14805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS14810	COG0346	lactoylglutathione lyase activity
L6451_RS14835	COG0714	Associated with various cellular activities
L6451_RS14860	COG0463	Glycosyl transferase, family 2
L6451_RS14880	COG0463	Glycosyl transferase, family 2
L6451_RS14890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L6451_RS14895	COG0753	catalase activity
L6451_RS14905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L6451_RS14915	COG1280	lysine exporter protein (LysE YggA)
L6451_RS14940	COG0714	Associated with various cellular activities
L6451_RS15060	COG0778	Nitroreductase
L6451_RS15065	COG1846	Transcriptional regulator
L6451_RS15100	COG1725	Transcriptional regulator
L6451_RS15120	COG0577	efflux transmembrane transporter activity
L6451_RS15120	COG1136	(ABC) transporter
L6451_RS15145	COG2207	Transcriptional regulator
L6451_RS15150	COG0456	acetyltransferase
L6451_RS15165	COG0697	spore germination
L6451_RS15170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS15215	COG0730	response to heat
L6451_RS15225	COG0833	amino acid
L6451_RS15235	COG4335	DNA alkylation repair
L6451_RS15270	COG0768	penicillin binding
L6451_RS15305	COG1984	allophanate hydrolase subunit 2
L6451_RS15310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L6451_RS15315	COG1414	Transcriptional regulator
L6451_RS15335	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6451_RS15340	COG0640	Transcriptional regulator
L6451_RS15350	COG1960	acyl-CoA dehydrogenase activity
L6451_RS15365	COG3314	Sporulation integral membrane protein YlbJ
L6451_RS15390	COG3848	Pyruvate phosphate dikinase
L6451_RS15390	COG0574	Belongs to the PEP-utilizing enzyme family
L6451_RS15395	COG1819	glycosyl
L6451_RS15400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS15415	COG5577	PFAM Coat F domain
L6451_RS15420	COG3403	YqcI/YcgG family
L6451_RS15425	COG1280	lysine exporter protein (LysE YggA)
L6451_RS15430	COG1113	amino acid transport
L6451_RS15460	COG1063	alcohol dehydrogenase
L6451_RS15495	COG4974	Belongs to the 'phage' integrase family
L6451_RS15570	COG0753	catalase activity
L6451_RS15575	COG0598	Magnesium transport protein CorA
L6451_RS15615	COG0415	Belongs to the DNA photolyase family
L6451_RS15620	COG0288	reversible hydration of carbon dioxide
L6451_RS15630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L6451_RS15635	COG5609	conserved protein (DUF2294)
L6451_RS15650	COG0714	Associated with various cellular activities
L6451_RS15660	COG1575	Belongs to the MenA family. Type 1 subfamily
L6451_RS15670	COG0803	Belongs to the bacterial solute-binding protein 9 family
L6451_RS15675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L6451_RS15680	COG1121	(ABC) transporter
L6451_RS15695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS15705	COG0798	PFAM Bile acid sodium symporter
L6451_RS15710	COG0346	lactoylglutathione lyase activity
L6451_RS15715	COG0640	Transcriptional regulator
L6451_RS15725	COG0456	acetyltransferase
L6451_RS15735	COG3320	Male sterility
L6451_RS15735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6451_RS15740	COG1309	transcriptional regulator
L6451_RS15745	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS15750	COG1522	sequence-specific DNA binding
L6451_RS15765	COG0346	lactoylglutathione lyase activity
L6451_RS15805	COG2814	Major facilitator Superfamily
L6451_RS15830	COG0745	RESPONSE REGULATOR receiver
L6451_RS15835	COG5002	protein histidine kinase activity
L6451_RS15835	COG3850	Histidine kinase
L6451_RS15860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L6451_RS15880	COG1476	TRANSCRIPTIONal
L6451_RS15905	COG0789	Transcriptional regulator
L6451_RS15910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L6451_RS15925	COG1136	(ABC) transporter
L6451_RS15930	COG0577	efflux transmembrane transporter activity
L6451_RS15945	COG3850	Histidine kinase
L6451_RS15945	COG5002	protein histidine kinase activity
L6451_RS15955	COG2364	Membrane
L6451_RS15960	COG1846	Transcriptional regulator
L6451_RS15965	COG0456	acetyltransferase
L6451_RS15970	COG2808	Putative FMN-binding domain
L6451_RS15975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS15980	COG2271	Major facilitator Superfamily
L6451_RS15985	COG1556	Lactate utilization protein
L6451_RS15990	COG1139	Iron-sulfur cluster binding protein
L6451_RS16000	COG0583	DNA-binding transcription factor activity
L6451_RS16020	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6451_RS16035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L6451_RS16055	COG1595	DNA-templated transcription, initiation
L6451_RS16070	COG0662	Cupin 2, conserved barrel domain protein
L6451_RS16075	COG2207	Transcriptional regulator
L6451_RS16075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6451_RS16090	COG3409	Peptidoglycan-binding domain 1 protein
L6451_RS16090	COG5632	N-Acetylmuramoyl-L-alanine amidase
L6451_RS16380	COG2373	Large extracellular alpha-helical protein
L6451_RS16400	COG0477	Major facilitator Superfamily
L6451_RS16410	COG1846	Transcriptional regulator
L6451_RS16415	COG2814	Major facilitator Superfamily
L6451_RS16425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6451_RS16430	COG1131	(ABC) transporter
L6451_RS16450	COG2076	Multidrug Resistance protein
L6451_RS16455	COG1309	transcriptional regulator
L6451_RS16465	COG1476	TRANSCRIPTIONal
L6451_RS16480	COG2031	fatty acid transporter
L6451_RS16490	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6451_RS16525	COG1122	ATPase activity
L6451_RS16535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L6451_RS16550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L6451_RS16555	COG1288	antiporter activity
L6451_RS16565	COG3409	Peptidoglycan-binding domain 1 protein
L6451_RS16565	COG5632	N-Acetylmuramoyl-L-alanine amidase
L6451_RS16575	COG3620	sequence-specific DNA binding
L6451_RS16585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L6451_RS16605	COG1733	regulation of RNA biosynthetic process
L6451_RS16610	COG0778	Nitroreductase
L6451_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS16640	COG1131	(ABC) transporter
L6451_RS16665	COG1011	Hydrolase
L6451_RS16675	COG2365	Tyrosine phosphatase family
L6451_RS16700	COG0346	lactoylglutathione lyase activity
L6451_RS16705	COG1940	carbohydrate kinase activity
L6451_RS16715	COG0110	maltose O-acetyltransferase activity
L6451_RS16725	COG0577	efflux transmembrane transporter activity
L6451_RS16725	COG1136	(ABC) transporter
L6451_RS16745	COG0628	permease
L6451_RS16765	COG2226	methyltransferase
L6451_RS16775	COG0477	Major facilitator Superfamily
L6451_RS16805	COG1253	flavin adenine dinucleotide binding
L6451_RS16810	COG0789	Transcriptional regulator
L6451_RS16820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L6451_RS16850	COG0697	spore germination
L6451_RS16855	COG1357	PFAM Pentapeptide repeats (8 copies)
L6451_RS16860	COG3813	Protein conserved in bacteria
L6451_RS16865	COG3328	transposase activity
L6451_RS16870	COG2706	6-phosphogluconolactonase activity
L6451_RS16875	COG1070	Carbohydrate kinase
L6451_RS16885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L6451_RS16890	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L6451_RS16900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L6451_RS16915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6451_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS16975	COG0814	amino acid
L6451_RS17005	COG1393	Belongs to the ArsC family
L6451_RS17010	COG1733	regulation of RNA biosynthetic process
L6451_RS17015	COG2188	Transcriptional regulator
L6451_RS17020	COG0673	inositol 2-dehydrogenase activity
L6451_RS17025	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L6451_RS17030	COG1733	regulation of RNA biosynthetic process
L6451_RS17035	COG1733	regulation of RNA biosynthetic process
L6451_RS17055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS17100	COG0318	PFAM AMP-dependent synthetase and ligase
L6451_RS17105	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6451_RS17110	COG1733	regulation of RNA biosynthetic process
L6451_RS17140	COG1191	sigma factor activity
L6451_RS17160	COG1309	transcriptional regulator
L6451_RS17180	COG3152	Membrane
L6451_RS17205	COG1151	hydroxylamine reductase activity
L6451_RS17215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS17220	COG3757	hydrolase, family 25
L6451_RS17220	COG3409	Peptidoglycan-binding domain 1 protein
L6451_RS17255	COG2072	flavoprotein involved in K transport
L6451_RS17290	COG1113	amino acid transport
L6451_RS17295	COG2814	Major facilitator Superfamily
L6451_RS17325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L6451_RS17330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6451_RS17335	COG3328	transposase activity
L6451_RS17350	COG3739	integral membrane protein
L6451_RS17355	COG0384	phenazine biosynthesis protein PhzF
L6451_RS17385	COG0583	DNA-binding transcription factor activity
L6451_RS17405	COG1193	negative regulation of DNA recombination
L6451_RS17420	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L6451_RS17425	COG1164	Oligoendopeptidase f
L6451_RS17435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6451_RS17460	COG0584	glycerophosphoryl diester phosphodiesterase
L6451_RS17485	COG0640	Transcriptional regulator
L6451_RS17490	COG0604	alcohol dehydrogenase
L6451_RS17500	COG0457	Tetratricopeptide repeat
L6451_RS17510	COG2808	Putative FMN-binding domain
L6451_RS17520	COG0456	acetyltransferase
L6451_RS17520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6451_RS17530	COG0385	Bile acid
L6451_RS17535	COG0277	FAD linked oxidase domain protein
L6451_RS17565	COG1216	Glycosyl transferase, family 2
L6451_RS17570	COG1024	Enoyl-CoA hydratase
L6451_RS17580	COG1285	pathogenesis
L6451_RS17595	COG2514	catechol 2,3-dioxygenase activity
L6451_RS17600	COG2720	vancomycin resistance protein
L6451_RS17640	COG0716	FMN binding
L6451_RS17670	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS17680	COG0165	Argininosuccinate lyase
L6451_RS17695	COG4145	pantothenate transmembrane transporter activity
L6451_RS17755	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS17765	COG1657	PFAM Prenyltransferase squalene oxidase
L6451_RS17770	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L6451_RS17775	COG2962	Rard protein
L6451_RS17780	COG3326	Membrane
L6451_RS17795	COG0489	protein tyrosine kinase activity
L6451_RS17805	COG0314	molybdopterin synthase activity
L6451_RS17810	COG0303	'Molybdopterin
L6451_RS17815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6451_RS17820	COG2116	formate transmembrane transporter activity
L6451_RS17830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L6451_RS17835	COG5609	conserved protein (DUF2294)
L6451_RS17840	COG2427	Protein of unknown function (DUF1641)
L6451_RS17845	COG3383	formate dehydrogenase (NAD+) activity
L6451_RS17850	COG0697	spore germination
L6451_RS17890	COG2226	methyltransferase
L6451_RS17895	COG4166	transmembrane transport
L6451_RS17905	COG4166	transmembrane transport
L6451_RS17910	COG4166	transmembrane transport
L6451_RS17915	COG1301	dicarboxylic acid transport
L6451_RS17920	COG1316	TRANSCRIPTIONal
L6451_RS17930	COG1595	DNA-templated transcription, initiation
L6451_RS17945	COG1131	(ABC) transporter
L6451_RS17970	COG0673	inositol 2-dehydrogenase activity
L6451_RS17975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L6451_RS17980	COG0187	DNA topoisomerase II activity
L6451_RS17985	COG1832	CoA-binding protein
L6451_RS17990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6451_RS17995	COG0745	RESPONSE REGULATOR receiver
L6451_RS18015	COG4841	protein insertion into membrane
L6451_RS18020	COG0824	Thioesterase
L6451_RS18050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6451_RS18060	COG1132	(ABC) transporter
L6451_RS18065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L6451_RS18105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L6451_RS18120	COG0183	Belongs to the thiolase family
L6451_RS18125	COG0318	PFAM AMP-dependent synthetase and ligase
L6451_RS18130	COG1268	BioY protein
L6451_RS18135	COG0318	PFAM AMP-dependent synthetase and ligase
L6451_RS18195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS18210	COG0400	carboxylic ester hydrolase activity
L6451_RS18215	COG0346	lactoylglutathione lyase activity
L6451_RS18220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6451_RS18225	COG0069	glutamate synthase activity
L6451_RS18230	COG1902	pentaerythritol trinitrate reductase activity
L6451_RS18235	COG1329	Transcriptional regulator
L6451_RS18240	COG0010	Belongs to the arginase family
L6451_RS18265	COG2226	methyltransferase
L6451_RS18300	COG3344	reverse transcriptase
L6451_RS18310	COG4846	Membrane protein involved in cytochrome C biogenesis
L6451_RS18315	COG0785	Cytochrome C biogenesis protein
L6451_RS18325	COG1473	amidohydrolase
L6451_RS18335	COG1131	(ABC) transporter
L6451_RS18345	COG0583	DNA-binding transcription factor activity
L6451_RS18355	COG1346	cytolysis
L6451_RS18370	COG0730	response to heat
L6451_RS18395	COG1132	(ABC) transporter
L6451_RS18400	COG1132	(ABC) transporter
L6451_RS18430	COG3639	organic phosphonate transmembrane transporter activity
L6451_RS18435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
L6451_RS18440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6451_RS18445	COG0737	Belongs to the 5'-nucleotidase family
L6451_RS18455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6451_RS18475	COG1695	Transcriptional regulator
L6451_RS18480	COG0174	glutamine synthetase
L6451_RS18485	COG0789	Transcriptional regulator
L6451_RS18490	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L6451_RS18495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L6451_RS18500	COG2860	membrane
L6451_RS18505	COG0464	growth
L6451_RS18540	COG3584	3D domain protein
L6451_RS18540	COG1388	LysM domain
L6451_RS18545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L6451_RS18545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L6451_RS18545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6451_RS18550	COG1105	Belongs to the carbohydrate kinase PfkB family
L6451_RS18555	COG1349	DNA-binding transcription factor activity
L6451_RS18560	COG1979	alcohol dehydrogenase
L6451_RS18565	COG2322	membrane
L6451_RS18575	COG1113	amino acid transport
L6451_RS18585	COG1408	metallophosphoesterase
L6451_RS18590	COG2116	formate transmembrane transporter activity
L6451_RS18600	COG2217	Heavy metal translocating P-type atpase
L6451_RS18605	COG2608	mercury ion transmembrane transporter activity
L6451_RS18610	COG1937	Protein conserved in bacteria
L6451_RS18650	COG2819	hydrolase of the alpha beta superfamily
L6451_RS18655	COG1120	ATPase activity
L6451_RS18660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS18665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS18670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6451_RS18675	COG0708	Exodeoxyribonuclease III
L6451_RS18680	COG2169	Transcriptional regulator
L6451_RS18685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L6451_RS18690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L6451_RS18700	COG2364	Membrane
L6451_RS18715	COG2267	carboxylic ester hydrolase activity
L6451_RS18720	COG0346	lactoylglutathione lyase activity
L6451_RS18725	COG3300	MHYT domain
L6451_RS18725	COG5001	Diguanylate cyclase
L6451_RS18745	COG1380	Effector of murein hydrolase LrgA
L6451_RS18750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6451_RS18770	COG1404	Belongs to the peptidase S8 family
L6451_RS18775	COG3773	Cell wall hydrolase
L6451_RS18780	COG0562	UDP-galactopyranose mutase
L6451_RS18785	COG1368	sulfuric ester hydrolase activity
L6451_RS18790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6451_RS18810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L6451_RS18815	COG2814	Major facilitator Superfamily
L6451_RS18825	COG0640	Transcriptional regulator
L6451_RS18845	COG4550	Control of competence regulator ComK, YlbF/YmcA
L6451_RS18855	COG1013	pyruvate-flavodoxin oxidoreductase activity
L6451_RS18860	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L6451_RS18860	COG0674	pyruvate-flavodoxin oxidoreductase activity
L6451_RS18870	COG2359	stage V sporulation protein S
L6451_RS18875	COG1692	metallophosphoesterase
L6451_RS18910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L6451_RS18915	COG1426	Protein conserved in bacteria
L6451_RS18930	COG0300	oxidoreductase activity
L6451_RS18935	COG0612	Peptidase, M16
L6451_RS18940	COG0612	Peptidase, M16
L6451_RS18945	COG1079	Belongs to the binding-protein-dependent transport system permease family
L6451_RS18950	COG4603	Belongs to the binding-protein-dependent transport system permease family
L6451_RS18955	COG3845	ABC transporter
L6451_RS18960	COG1744	ABC transporter substrate-binding protein PnrA-like
L6451_RS18965	COG2188	Transcriptional regulator
L6451_RS18970	COG1674	ftsk spoiiie
L6451_RS18980	COG0740	serine-type endopeptidase activity
L6451_RS18985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6451_RS18995	COG0527	aspartate kinase activity
L6451_RS19000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L6451_RS19005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L6451_RS19010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L6451_RS19015	COG1873	PFAM PRC-barrel domain
L6451_RS19020	COG0612	Peptidase, M16
L6451_RS19025	COG0726	polysaccharide deacetylase
L6451_RS19040	COG0196	riboflavin kinase activity
L6451_RS19055	COG1550	Protein conserved in bacteria
L6451_RS19065	COG1358	cellular component organization or biogenesis
L6451_RS19070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L6451_RS19075	COG0195	Participates in both transcription termination and antitermination
L6451_RS19105	COG0750	zinc metalloprotease
L6451_RS19115	COG4589	Belongs to the CDS family
L6451_RS19130	COG0528	UMP kinase activity
L6451_RS19160	COG4974	Belongs to the 'phage' integrase family
L6451_RS19170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L6451_RS19175	COG0758	DNA mediated transformation
L6451_RS19180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L6451_RS19220	COG1837	Belongs to the UPF0109 family
L6451_RS19230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L6451_RS19240	COG0552	protein localization to endoplasmic reticulum
L6451_RS19245	COG1196	nuclear chromosome segregation
L6451_RS19255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6451_RS19260	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS19265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L6451_RS19280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L6451_RS19285	COG1461	Dihydroxyacetone kinase
L6451_RS19290	COG1302	Protein conserved in bacteria
L6451_RS19305	COG1564	THIamine pyrophosphokinase
L6451_RS19310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L6451_RS19315	COG1162	GTPase activity
L6451_RS19320	COG0515	serine threonine protein kinase
L6451_RS19320	COG2815	serine threonine protein kinase
L6451_RS19325	COG0631	protein serine/threonine phosphatase activity
L6451_RS19335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L6451_RS19335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L6451_RS19345	COG0242	peptide deformylase activity
L6451_RS19350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L6451_RS19355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L6451_RS19375	COG1561	YicC-like family, N-terminal region
L6451_RS19380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L6451_RS19390	COG0006	proline dipeptidase activity
L6451_RS19410	COG3069	C4-dicarboxylate transmembrane transporter activity
L6451_RS19470	COG0564	pseudouridine synthase activity
L6451_RS19490	COG3599	regulation of cell shape
L6451_RS19495	COG2302	S4 RNA-binding domain
L6451_RS19500	COG0762	integral membrane protein
L6451_RS19510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L6451_RS19515	COG1496	oxidoreductase activity
L6451_RS19520	COG1873	PFAM PRC-barrel domain
L6451_RS19525	COG1191	sigma factor activity
L6451_RS19530	COG1191	sigma factor activity
L6451_RS19540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L6451_RS19545	COG0849	cell division
L6451_RS19550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L6451_RS19565	COG0772	Belongs to the SEDS family
L6451_RS19580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L6451_RS19585	COG0768	penicillin binding
L6451_RS19590	COG0768	penicillin binding
L6451_RS19595	COG4839	cell division protein FtsL
L6451_RS19610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L6451_RS19625	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L6451_RS19630	COG1399	metal-binding, possibly nucleic acid-binding protein
L6451_RS19640	COG3480	Lon protease (S16) C-terminal proteolytic domain
L6451_RS19645	COG1752	Esterase of the alpha-beta hydrolase superfamily
L6451_RS19650	COG3314	Sporulation integral membrane protein YlbJ
L6451_RS19660	COG0742	ribosomal rna small subunit methyltransferase
L6451_RS19675	COG3679	Belongs to the UPF0342 family
L6451_RS19680	COG0406	alpha-ribazole phosphatase activity
L6451_RS19695	COG2340	Cysteine-rich secretory protein family
L6451_RS19710	COG3336	cytochrome c oxidase
L6451_RS19745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L6451_RS19750	COG0772	Belongs to the SEDS family
L6451_RS19760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L6451_RS19765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L6451_RS19775	COG4896	Protein conserved in bacteria
L6451_RS19790	COG1217	gtp-binding protein TYPA
L6451_RS19800	COG0483	inositol monophosphate 1-phosphatase activity
L6451_RS19820	COG1982	Orn Lys Arg decarboxylase major
L6451_RS19870	COG0022	dehydrogenase e1 component
L6451_RS19875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6451_RS19885	COG0242	peptide deformylase activity
L6451_RS19890	COG0561	phosphatase activity
L6451_RS19900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6451_RS19905	COG0569	domain protein
L6451_RS19925	COG0583	DNA-binding transcription factor activity
L6451_RS19930	COG0517	IMP dehydrogenase activity
L6451_RS19940	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
L6451_RS19950	COG4703	Protein of unknown function (DUF1797)
L6451_RS19965	COG2200	EAL domain
L6451_RS19970	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS19975	COG1408	metallophosphoesterase
L6451_RS19985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
L6451_RS20020	COG2814	Major facilitator Superfamily
L6451_RS20040	COG3209	COG3209 Rhs family protein
L6451_RS20050	COG2205	protein histidine kinase activity
L6451_RS20060	COG0436	Aminotransferase
L6451_RS20065	COG1609	Transcriptional regulator
L6451_RS20070	COG3833	ABC-type maltose transport systems, permease component
L6451_RS20075	COG1175	transmembrane transport
L6451_RS20080	COG2182	Extracellular solute-binding protein
L6451_RS20090	COG0366	Alpha amylase catalytic
L6451_RS20095	COG3842	ATPase activity
L6451_RS20135	COG0183	Belongs to the thiolase family
L6451_RS20170	COG1695	Transcriptional regulator
L6451_RS20175	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS20195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L6451_RS20200	COG0436	Aminotransferase
L6451_RS20235	COG2084	Dehydrogenase
L6451_RS20240	COG2199	diguanylate cyclase activity
L6451_RS20245	COG0778	Nitroreductase
L6451_RS20270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS20270	COG1263	PTS System
L6451_RS20270	COG2190	(PTS) system
L6451_RS20275	COG3711	transcriptional antiterminator
L6451_RS20285	COG2188	Transcriptional regulator
L6451_RS20295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L6451_RS20320	COG1547	Domain of unknown function (DUF309)
L6451_RS20325	COG0456	acetyltransferase
L6451_RS20335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L6451_RS20340	COG4086	secreted protein
L6451_RS20345	COG0561	phosphatase activity
L6451_RS20350	COG0697	spore germination
L6451_RS20365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6451_RS20390	COG0733	neurotransmitter:sodium symporter activity
L6451_RS20410	COG1686	Belongs to the peptidase S11 family
L6451_RS20415	COG1725	Transcriptional regulator
L6451_RS20420	COG1131	(ABC) transporter
L6451_RS20440	COG1846	Transcriptional regulator
L6451_RS20455	COG0598	Magnesium transport protein CorA
L6451_RS20480	COG4974	Belongs to the 'phage' integrase family
L6451_RS20490	COG0735	belongs to the Fur family
L6451_RS20495	COG1300	Membrane
L6451_RS20515	COG0667	Aldo Keto reductase
L6451_RS20520	COG0656	L-ascorbic acid biosynthetic process
L6451_RS20525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6451_RS20525	COG0456	acetyltransferase
L6451_RS20535	COG4085	toxin activity
L6451_RS20535	COG0737	Belongs to the 5'-nucleotidase family
L6451_RS20535	COG1525	nuclease
L6451_RS20545	COG0596	Alpha beta hydrolase
L6451_RS20550	COG2056	Na+-H+ antiporter family
L6451_RS20555	COG1609	Transcriptional regulator
L6451_RS20560	COG0454	-acetyltransferase
L6451_RS20565	COG1073	alpha beta
L6451_RS20580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L6451_RS20580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L6451_RS20585	COG0307	riboflavin synthase, alpha
L6451_RS20610	COG4106	trans-aconitate 2-methyltransferase activity
L6451_RS20615	COG1073	alpha beta
L6451_RS20615	COG2226	methyltransferase
L6451_RS20630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6451_RS20640	COG1757	Na H antiporter
L6451_RS20645	COG0737	Belongs to the 5'-nucleotidase family
L6451_RS20655	COG1522	sequence-specific DNA binding
L6451_RS20675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L6451_RS20700	COG0300	oxidoreductase activity
L6451_RS20705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS20710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6451_RS20715	COG1760	l-serine dehydratase
L6451_RS20720	COG1760	l-serine dehydratase
L6451_RS20740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L6451_RS20750	COG2195	Cleaves the N-terminal amino acid of tripeptides
L6451_RS20755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS20770	COG1376	ErfK ybiS ycfS ynhG family protein
L6451_RS20775	COG4129	membrane
L6451_RS20780	COG1126	abc transporter atp-binding protein
L6451_RS20785	COG0765	amino acid transport
L6451_RS20790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6451_RS20800	COG2816	NAD+ diphosphatase activity
L6451_RS20805	COG0772	Belongs to the SEDS family
L6451_RS20810	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6451_RS20815	COG0022	dehydrogenase e1 component
L6451_RS20820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6451_RS20825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L6451_RS20840	COG0280	phosphate acetyltransferase
L6451_RS20845	COG3290	protein histidine kinase activity
L6451_RS20845	COG3829	transcription factor binding
L6451_RS20855	COG0584	glycerophosphoryl diester phosphodiesterase
L6451_RS20860	COG3093	addiction module antidote protein HigA
L6451_RS20870	COG0745	RESPONSE REGULATOR receiver
L6451_RS20875	COG0750	zinc metalloprotease
L6451_RS20880	COG0497	DNA recombination
L6451_RS20890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L6451_RS20900	COG0142	geranyltranstransferase activity
L6451_RS20925	COG1302	Protein conserved in bacteria
L6451_RS20930	COG0439	Biotin carboxylase
L6451_RS20935	COG0511	ligase activity, forming carbon-carbon bonds
L6451_RS20980	COG3854	ATPases associated with a variety of cellular activities
L6451_RS21005	COG0006	proline dipeptidase activity
L6451_RS21020	COG3872	metal-dependent enzyme
L6451_RS21030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L6451_RS21065	COG0095	Lipoate-protein ligase
L6451_RS21070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6451_RS21075	COG1609	Transcriptional regulator
L6451_RS21085	COG2076	Multidrug Resistance protein
L6451_RS21090	COG2076	Multidrug Resistance protein
L6451_RS21125	COG1131	(ABC) transporter
L6451_RS21130	COG1725	Transcriptional regulator
L6451_RS21160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6451_RS21215	COG4970	Tfp pilus assembly protein FimT
L6451_RS21225	COG1459	type II secretion system
L6451_RS21230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L6451_RS21280	COG0646	methionine synthase
L6451_RS21280	COG1410	methionine synthase
L6451_RS21285	COG0646	methionine synthase
L6451_RS21285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L6451_RS21290	COG0626	cystathionine gamma-synthase activity
L6451_RS21295	COG0626	cystathionine gamma-synthase activity
L6451_RS21315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS21325	COG1940	carbohydrate kinase activity
L6451_RS21330	COG4483	Protein conserved in bacteria
L6451_RS21335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L6451_RS21340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L6451_RS21345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L6451_RS21350	COG0704	Plays a role in the regulation of phosphate uptake
L6451_RS21360	COG0581	inorganic phosphate transmembrane transporter activity
L6451_RS21365	COG0573	inorganic phosphate transmembrane transporter activity
L6451_RS21370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L6451_RS21380	COG0768	penicillin binding
L6451_RS21385	COG0477	Major facilitator Superfamily
L6451_RS21390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6451_RS21415	COG0735	belongs to the Fur family
L6451_RS21420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L6451_RS21425	COG1121	(ABC) transporter
L6451_RS21430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS21460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L6451_RS21465	COG2384	SAM-dependent methyltransferase
L6451_RS21470	COG2010	Cytochrome c
L6451_RS21475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L6451_RS21480	COG0358	DNA primase activity
L6451_RS21490	COG0517	IMP dehydrogenase activity
L6451_RS21505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L6451_RS21510	COG0295	cytidine deaminase activity
L6451_RS21515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L6451_RS21525	COG1480	7TM receptor with intracellular HD hydrolase
L6451_RS21530	COG1702	phosphate starvation-inducible protein PhoH
L6451_RS21545	COG1610	YqeY-like protein
L6451_RS21550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
L6451_RS21555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L6451_RS21560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L6451_RS21590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L6451_RS21595	COG1733	regulation of RNA biosynthetic process
L6451_RS21620	COG1466	dna polymerase III delta subunit
L6451_RS21630	COG0658	competence protein
L6451_RS21630	COG2333	competence protein COMEC
L6451_RS21635	COG2131	deaminase
L6451_RS21640	COG1596	polysaccharide export
L6451_RS21640	COG1555	photosystem II stabilization
L6451_RS21645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6451_RS21650	COG2226	methyltransferase
L6451_RS21655	COG0799	negative regulation of ribosome biogenesis
L6451_RS21660	COG1713	HD superfamily hydrolase involved in NAD metabolism
L6451_RS21670	COG1534	Rna-binding protein
L6451_RS21680	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L6451_RS21685	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L6451_RS21710	COG1595	DNA-templated transcription, initiation
L6451_RS21720	COG0778	Nitroreductase
L6451_RS21725	COG2357	RelA SpoT domain protein
L6451_RS21735	COG1785	Belongs to the alkaline phosphatase family
L6451_RS21745	COG2267	carboxylic ester hydrolase activity
L6451_RS21780	COG1404	Belongs to the peptidase S8 family
L6451_RS21785	COG3186	Phenylalanine-4-hydroxylase
L6451_RS21795	COG2514	catechol 2,3-dioxygenase activity
L6451_RS21800	COG2259	Doxx family
L6451_RS21840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L6451_RS21850	COG1454	alcohol dehydrogenase
L6451_RS21850	COG1012	belongs to the aldehyde dehydrogenase family
L6451_RS21855	COG0626	cystathionine gamma-synthase activity
L6451_RS21860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6451_RS21885	COG0768	penicillin binding
L6451_RS21900	COG0826	peptidase U32
L6451_RS21905	COG0826	peptidase U32
L6451_RS21910	COG4122	O-methyltransferase activity
L6451_RS21915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L6451_RS21945	COG0628	permease
L6451_RS21965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L6451_RS21980	COG1104	cysteine desulfurase activity
L6451_RS21985	COG1959	2 iron, 2 sulfur cluster binding
L6451_RS21990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L6451_RS22000	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L6451_RS22040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L6451_RS22050	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L6451_RS22050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L6451_RS22055	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L6451_RS22060	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L6451_RS22060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L6451_RS22070	COG2244	polysaccharide biosynthetic process
L6451_RS22075	COG2323	membrane
L6451_RS22085	COG1862	Preprotein translocase
L6451_RS22115	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L6451_RS22125	COG0697	spore germination
L6451_RS22130	COG0640	Transcriptional regulator
L6451_RS22155	COG0157	Belongs to the NadC ModD family
L6451_RS22160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L6451_RS22165	COG1104	cysteine desulfurase activity
L6451_RS22170	COG1827	regulation of RNA biosynthetic process
L6451_RS22175	COG2258	MOSC domain
L6451_RS22180	COG0077	Prephenate dehydratase
L6451_RS22185	COG0577	efflux transmembrane transporter activity
L6451_RS22190	COG0577	efflux transmembrane transporter activity
L6451_RS22195	COG1136	(ABC) transporter
L6451_RS22200	COG5002	protein histidine kinase activity
L6451_RS22205	COG0745	RESPONSE REGULATOR receiver
L6451_RS22215	COG3290	protein histidine kinase activity
L6451_RS22225	COG2868	ribosomal protein
L6451_RS22230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L6451_RS22235	COG1530	ribonuclease E activity
L6451_RS22240	COG1994	Peptidase M50
L6451_RS22245	COG0739	heme binding
L6451_RS22250	COG2894	cell division
L6451_RS22270	COG1077	Cell shape determining protein MreB Mrl
L6451_RS22310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L6451_RS22310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L6451_RS22435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
L6451_RS22475	COG0285	dihydrofolate synthase activity
L6451_RS22490	COG1388	LysM domain
L6451_RS22500	COG0113	porphobilinogen synthase activity
L6451_RS22505	COG1587	Uroporphyrinogen-III synthase
L6451_RS22515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L6451_RS22525	COG1846	Transcriptional regulator
L6451_RS22530	COG1764	response to oxidative stress
L6451_RS22545	COG1067	ATP-dependent peptidase activity
L6451_RS22545	COG0470	DNA polymerase III
L6451_RS22595	COG0622	Phosphoesterase
L6451_RS22610	COG5401	PFAM Sporulation and spore germination
L6451_RS22625	COG2197	response regulator
L6451_RS22630	COG2233	PERMEase
L6451_RS22635	COG0402	S-adenosylhomocysteine deaminase activity
L6451_RS22640	COG1983	PspC domain protein
L6451_RS22645	COG1396	sequence-specific DNA binding
L6451_RS22650	COG0697	spore germination
L6451_RS22660	COG1959	2 iron, 2 sulfur cluster binding
L6451_RS22665	COG1668	transmembrane transport
L6451_RS22670	COG4152	abc transporter atp-binding protein
L6451_RS22675	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
L6451_RS22680	COG1360	Flagellar Motor Protein
L6451_RS22685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L6451_RS22690	COG1876	peptidase activity
L6451_RS22695	COG0824	Thioesterase
L6451_RS22700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L6451_RS22705	COG1053	succinate dehydrogenase
L6451_RS22710	COG2009	succinate dehydrogenase
L6451_RS22715	COG1719	4-vinyl reductase, 4VR
L6451_RS22725	COG3118	belongs to the thioredoxin family
L6451_RS22730	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L6451_RS22735	COG2086	electron transfer activity
L6451_RS22740	COG1024	Enoyl-CoA hydratase
L6451_RS22745	COG1309	transcriptional regulator
L6451_RS22750	COG0318	PFAM AMP-dependent synthetase and ligase
L6451_RS22770	COG2318	DinB family
L6451_RS22795	COG1131	(ABC) transporter
L6451_RS22800	COG2205	protein histidine kinase activity
L6451_RS22805	COG0745	RESPONSE REGULATOR receiver
L6451_RS22815	COG4895	conserved protein (DUF2196)
L6451_RS22820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L6451_RS22835	COG4509	Sortase family
L6451_RS22840	COG1120	ATPase activity
L6451_RS22855	COG5386	Cell surface protein
L6451_RS22860	COG5386	Cell surface protein
L6451_RS22865	COG1114	Component of the transport system for branched-chain amino acids
L6451_RS22870	COG1187	pseudouridine synthase activity
L6451_RS22880	COG1796	DNA polymerase
L6451_RS22880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L6451_RS22885	COG1286	toxin biosynthetic process
L6451_RS22930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L6451_RS22940	COG1418	mRNA catabolic process
L6451_RS22950	COG2814	Major facilitator Superfamily
L6451_RS22955	COG1566	PFAM secretion protein HlyD family protein
L6451_RS22960	COG1309	transcriptional regulator
L6451_RS22965	COG1363	Peptidase, m42
L6451_RS22990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L6451_RS23000	COG1484	DNA-dependent DNA replication
L6451_RS23005	COG3611	Membrane attachment protein
L6451_RS23015	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
L6451_RS23020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L6451_RS23025	COG0237	dephospho-CoA kinase activity
L6451_RS23030	COG1971	Probably functions as a manganese efflux pump
L6451_RS23040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6451_RS23040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6451_RS23045	COG5002	protein histidine kinase activity
L6451_RS23050	COG0745	RESPONSE REGULATOR receiver
L6451_RS23070	COG0538	isocitrate dehydrogenase activity
L6451_RS23075	COG0372	Belongs to the citrate synthase family
L6451_RS23085	COG0628	permease
L6451_RS23090	COG3030	protein affecting phage T7 exclusion by the F plasmid
L6451_RS23115	COG1725	Transcriptional regulator
L6451_RS23120	COG0281	malic enzyme
L6451_RS23125	COG0587	DNA-directed DNA polymerase activity
L6451_RS23140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L6451_RS23155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6451_RS23165	COG4109	DRTGG domain
L6451_RS23180	COG0006	proline dipeptidase activity
L6451_RS23215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS23220	COG0662	Cupin 2, conserved barrel domain protein
L6451_RS23235	COG1028	Short-chain dehydrogenase reductase Sdr
L6451_RS23240	COG0589	response to stress
L6451_RS23280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS23295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L6451_RS23300	COG0827	DNA restriction-modification system
L6451_RS23305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L6451_RS23315	COG3874	Sporulation protein YtfJ
L6451_RS23330	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L6451_RS23340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6451_RS23355	COG1104	cysteine desulfurase activity
L6451_RS23365	COG0583	DNA-binding transcription factor activity
L6451_RS23370	COG0697	spore germination
L6451_RS23375	COG1309	transcriptional regulator
L6451_RS23380	COG1956	GAF domain-containing protein
L6451_RS23385	COG0626	cystathionine gamma-synthase activity
L6451_RS23430	COG1595	DNA-templated transcription, initiation
L6451_RS23440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6451_RS23445	COG0454	-acetyltransferase
L6451_RS23450	COG0517	IMP dehydrogenase activity
L6451_RS23455	COG0123	including yeast histone deacetylase and acetoin utilization protein
L6451_RS23460	COG2267	carboxylic ester hydrolase activity
L6451_RS23470	COG0745	RESPONSE REGULATOR receiver
L6451_RS23480	COG0666	response to abiotic stimulus
L6451_RS23485	COG2972	Histidine kinase
L6451_RS23485	COG0745	RESPONSE REGULATOR receiver
L6451_RS23540	COG1609	Transcriptional regulator
L6451_RS23545	COG4851	CamS sex pheromone cAM373 precursor
L6451_RS23550	COG3118	belongs to the thioredoxin family
L6451_RS23560	COG2309	aminopeptidase activity
L6451_RS23570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS23575	COG0697	spore germination
L6451_RS23580	COG0789	Transcriptional regulator
L6451_RS23585	COG1695	Transcriptional regulator
L6451_RS23605	COG1674	ftsk spoiiie
L6451_RS23605	COG1674	ftsk spoiiie
L6451_RS23615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6451_RS23625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6451_RS23630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
L6451_RS23635	COG1363	Peptidase, m42
L6451_RS23645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS23660	COG0510	thiamine kinase activity
L6451_RS23665	COG1523	belongs to the glycosyl hydrolase 13 family
L6451_RS23675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6451_RS23680	COG1349	DNA-binding transcription factor activity
L6451_RS23685	COG1187	pseudouridine synthase activity
L6451_RS23690	COG2244	polysaccharide biosynthetic process
L6451_RS23695	COG2081	HI0933 family
L6451_RS23705	COG2814	Major facilitator Superfamily
L6451_RS23715	COG3832	glyoxalase III activity
L6451_RS23735	COG1329	Transcriptional regulator
L6451_RS23760	COG0314	molybdopterin synthase activity
L6451_RS23775	COG1763	Mo-molybdopterin cofactor biosynthetic process
L6451_RS23780	COG0303	'Molybdopterin
L6451_RS23790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6451_RS23795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L6451_RS23815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6451_RS23825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L6451_RS23870	COG2814	Major facilitator Superfamily
L6451_RS23880	COG0475	glutathione-regulated potassium exporter activity
L6451_RS23885	COG0490	domain, Protein
L6451_RS23890	COG0582	viral genome integration into host DNA
L6451_RS23900	COG1136	(ABC) transporter
L6451_RS23920	COG1242	4 iron, 4 sulfur cluster binding
L6451_RS23925	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L6451_RS23940	COG1794	racemase activity, acting on amino acids and derivatives
L6451_RS23965	COG2267	carboxylic ester hydrolase activity
L6451_RS23970	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L6451_RS23975	COG0671	phosphoesterase, PA-phosphatase related
L6451_RS23980	COG0438	transferase activity, transferring glycosyl groups
L6451_RS23990	COG0521	Mo-molybdopterin cofactor biosynthetic process
L6451_RS24060	COG5002	protein histidine kinase activity
L6451_RS24065	COG4191	Histidine kinase
L6451_RS24070	COG2267	carboxylic ester hydrolase activity
L6451_RS24075	COG1368	sulfuric ester hydrolase activity
L6451_RS24090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6451_RS24095	COG1116	anion transmembrane transporter activity
L6451_RS24100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6451_RS24125	COG0494	nUDIX hydrolase
L6451_RS24155	COG0288	reversible hydration of carbon dioxide
L6451_RS24160	COG1271	oxidase subunit
L6451_RS24165	COG1294	oxidase, subunit
L6451_RS24185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS24210	COG1842	Phage shock protein A
L6451_RS24240	COG5002	protein histidine kinase activity
L6451_RS24245	COG0745	RESPONSE REGULATOR receiver
L6451_RS24275	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L6451_RS24280	COG1597	lipid kinase activity
L6451_RS24305	COG0586	Pfam SNARE associated Golgi protein
L6451_RS24315	COG4977	sequence-specific DNA binding
L6451_RS24325	COG0577	efflux transmembrane transporter activity
L6451_RS24330	COG1136	(ABC) transporter
L6451_RS24335	COG2207	Transcriptional regulator
L6451_RS24335	COG3708	Transcriptional regulator
L6451_RS24350	COG0745	RESPONSE REGULATOR receiver
L6451_RS24355	COG2205	protein histidine kinase activity
L6451_RS24360	COG0577	efflux transmembrane transporter activity
L6451_RS24365	COG0577	efflux transmembrane transporter activity
L6451_RS24370	COG1136	(ABC) transporter
L6451_RS24375	COG0577	efflux transmembrane transporter activity
L6451_RS24400	COG2188	Transcriptional regulator
L6451_RS24420	COG3964	amidohydrolase
L6451_RS24445	COG4948	Mandelate Racemase Muconate Lactonizing
L6451_RS24455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L6451_RS24460	COG0596	Alpha beta hydrolase
L6451_RS24470	COG1169	isochorismate synthase
L6451_RS24475	COG1575	Belongs to the MenA family. Type 1 subfamily
L6451_RS24480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L6451_RS24595	COG0058	SHG alpha-glucan phosphorylase activity
L6451_RS24605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L6451_RS24625	COG1404	Belongs to the peptidase S8 family
L6451_RS24640	COG1595	DNA-templated transcription, initiation
L6451_RS24735	COG0544	peptidyl-prolyl cis-trans isomerase activity
L6451_RS24770	COG1285	pathogenesis
L6451_RS24775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L6451_RS24790	COG2155	Conserved Protein
L6451_RS24795	COG1098	S1 RNA binding domain
L6451_RS24800	COG0436	Aminotransferase
L6451_RS24805	COG1522	sequence-specific DNA binding
L6451_RS24810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L6451_RS24815	COG2267	carboxylic ester hydrolase activity
L6451_RS24825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L6451_RS24845	COG5018	Exonuclease
L6451_RS24850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6451_RS24875	COG2050	protein possibly involved in aromatic compounds catabolism
L6451_RS24885	COG1268	BioY protein
L6451_RS24890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L6451_RS24895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L6451_RS24910	COG3584	3D domain protein
L6451_RS24925	COG1252	NADH dehydrogenase
L6451_RS24935	COG3708	Transcriptional regulator
L6451_RS24950	COG1683	Conserved Protein
L6451_RS24960	COG0316	Belongs to the HesB IscA family
L6451_RS24985	COG1252	NADH dehydrogenase
L6451_RS24995	COG2274	protein secretion by the type I secretion system
L6451_RS25000	COG0390	transport system, permease component
L6451_RS25010	COG2824	Alkylphosphonate utilization operon protein PhnA
L6451_RS25030	COG4837	Protein of unknown function (DUF1462)
L6451_RS25035	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L6451_RS25045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6451_RS25050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L6451_RS25060	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6451_RS25065	COG0647	UMP catabolic process
L6451_RS25075	COG2445	Protein of unknown function DUF86
L6451_RS25080	COG1494	fructose-1,6-bisphosphatase
L6451_RS25095	COG4470	Protein conserved in bacteria
L6451_RS25105	COG0789	Transcriptional regulator
L6451_RS25110	COG4377	Putative membrane peptidase family (DUF2324)
L6451_RS25135	COG0739	heme binding
L6451_RS25145	COG3377	Domain of unknown function (DUF1805)
L6451_RS25150	COG0737	Belongs to the 5'-nucleotidase family
L6451_RS25155	COG0719	Fe-S assembly protein
L6451_RS25160	COG0822	iron-sulfur transferase activity
L6451_RS25165	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L6451_RS25170	COG0719	Fe-S assembly protein
L6451_RS25175	COG0396	ATPase activity
L6451_RS25180	COG1464	Belongs to the NlpA lipoprotein family
L6451_RS25185	COG1464	Belongs to the NlpA lipoprotein family
L6451_RS25190	COG2011	ABC-type metal ion transport system permease component
L6451_RS25205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6451_RS25210	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L6451_RS25220	COG1393	Belongs to the ArsC family
L6451_RS25280	COG1396	sequence-specific DNA binding
L6451_RS25290	COG1309	transcriptional regulator
L6451_RS25295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6451_RS25300	COG1960	acyl-CoA dehydrogenase activity
L6451_RS25305	COG0183	Belongs to the thiolase family
L6451_RS25310	COG1250	3-hydroxyacyl-CoA dehydrogenase
L6451_RS25310	COG1024	Enoyl-CoA hydratase
L6451_RS25320	COG1686	Belongs to the peptidase S11 family
L6451_RS25335	COG0011	TIGRFAM Protein of
L6451_RS25340	COG0840	transmembrane signaling receptor activity
L6451_RS25355	COG2814	Major facilitator Superfamily
L6451_RS25360	COG0531	amino acid
L6451_RS25385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6451_RS25430	COG0586	Pfam SNARE associated Golgi protein
L6451_RS25440	COG1376	ErfK ybiS ycfS ynhG family protein
L6451_RS25445	COG0745	RESPONSE REGULATOR receiver
L6451_RS25450	COG5002	protein histidine kinase activity
L6451_RS25475	COG0840	transmembrane signaling receptor activity
L6451_RS25480	COG2151	metal-sulfur cluster biosynthetic enzyme
L6451_RS25485	COG3227	Zinc metalloprotease (Elastase)
L6451_RS25490	COG1741	Belongs to the pirin family
L6451_RS25505	COG0475	glutathione-regulated potassium exporter activity
L6451_RS25510	COG0490	domain, Protein
L6451_RS25515	COG1115	amino acid carrier protein
L6451_RS25520	COG0783	Belongs to the Dps family
L6451_RS25535	COG1611	Belongs to the LOG family
L6451_RS25550	COG2311	Membrane
L6451_RS25555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS25560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS25565	COG1115	amino acid carrier protein
L6451_RS25570	COG1115	amino acid carrier protein
L6451_RS25575	COG2910	NAD(P)H-binding
L6451_RS25600	COG0656	L-ascorbic acid biosynthetic process
L6451_RS25605	COG2814	Major facilitator Superfamily
L6451_RS25610	COG1733	regulation of RNA biosynthetic process
L6451_RS25620	COG1252	NADH dehydrogenase
L6451_RS25625	COG3328	transposase activity
L6451_RS25630	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L6451_RS25645	COG0840	transmembrane signaling receptor activity
L6451_RS25645	COG3290	protein histidine kinase activity
L6451_RS25680	COG0488	(ABC) transporter
L6451_RS25685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6451_RS25695	COG2814	Major facilitator Superfamily
L6451_RS25745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6451_RS25750	COG0697	spore germination
L6451_RS25770	COG0557	exoribonuclease II activity
L6451_RS25775	COG1647	Serine aminopeptidase, S33
L6451_RS25780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L6451_RS25785	COG1346	cytolysis
L6451_RS25820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L6451_RS25835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L6451_RS25860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6451_RS25875	COG2323	membrane
L6451_RS25885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6451_RS25895	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L6451_RS25905	COG1051	belongs to the nudix hydrolase family
L6451_RS25915	COG0492	ferredoxin-NADP+ reductase activity
L6451_RS25920	COG0457	Tetratricopeptide repeat
L6451_RS25925	COG0110	maltose O-acetyltransferase activity
L6451_RS25945	COG1950	PFAM Membrane protein of
L6451_RS25955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L6451_RS25960	COG0556	nucleotide-excision repair
L6451_RS25975	COG0789	Transcriptional regulator
L6451_RS26000	COG2855	membrane
L6451_RS26005	COG0583	DNA-binding transcription factor activity
L6451_RS26015	COG0655	NAD(P)H dehydrogenase (quinone) activity
L6451_RS26020	COG0488	(ABC) transporter
L6451_RS26030	COG1132	(ABC) transporter
L6451_RS26040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6451_RS26045	COG0793	Belongs to the peptidase S41A family
L6451_RS26045	COG3409	Peptidoglycan-binding domain 1 protein
L6451_RS26050	COG2177	Part of the ABC transporter FtsEX involved in
L6451_RS26055	COG2884	Cell division ATP-binding protein ftsE
L6451_RS26075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L6451_RS26080	COG1278	Cold shock
L6451_RS26085	COG1040	competence protein
L6451_RS26090	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L6451_RS26100	COG1733	regulation of RNA biosynthetic process
L6451_RS26105	COG1307	EDD domain protein, DegV family
L6451_RS26110	COG1739	Uncharacterized protein family UPF0029
L6451_RS26115	COG1316	TRANSCRIPTIONal
L6451_RS26120	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L6451_RS26125	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L6451_RS26130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L6451_RS26140	COG3933	PFAM sigma-54 factor interaction domain-containing protein
L6451_RS26140	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L6451_RS26160	COG1486	melibiose metabolic process
L6451_RS26165	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6451_RS26170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6451_RS26180	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L6451_RS26200	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6451_RS26210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6451_RS26215	COG1301	dicarboxylic acid transport
L6451_RS26225	COG0346	lactoylglutathione lyase activity
L6451_RS26245	COG1511	domain protein
L6451_RS26250	COG0583	DNA-binding transcription factor activity
L6451_RS26255	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
L6451_RS26265	COG1271	oxidase subunit
L6451_RS26270	COG1294	oxidase, subunit
L6451_RS26275	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6451_RS26310	COG1620	l-lactate permease
L6451_RS26320	COG2389	metal-binding protein
L6451_RS26330	COG1368	sulfuric ester hydrolase activity
L6451_RS26340	COG1388	LysM domain
L6451_RS26340	COG0791	NLP P60 protein
L6451_RS26345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6451_RS26355	COG1215	transferase activity, transferring glycosyl groups
L6451_RS26365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6451_RS26370	COG3584	3D domain protein
L6451_RS26370	COG1388	LysM domain
L6451_RS26380	COG4715	Zinc finger, swim domain protein
L6451_RS26385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6451_RS26430	COG0577	efflux transmembrane transporter activity
L6451_RS26435	COG1136	(ABC) transporter
L6451_RS26470	COG5002	protein histidine kinase activity
L6451_RS26470	COG3850	Histidine kinase
L6451_RS26475	COG0745	RESPONSE REGULATOR receiver
L6451_RS26480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L6451_RS26500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L6451_RS26510	COG0438	transferase activity, transferring glycosyl groups
L6451_RS26530	COG0438	transferase activity, transferring glycosyl groups
L6451_RS26535	COG0438	transferase activity, transferring glycosyl groups
L6451_RS26540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L6451_RS26545	COG0151	Belongs to the GarS family
L6451_RS26555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L6451_RS26560	COG1086	Polysaccharide biosynthesis protein
L6451_RS26565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L6451_RS26570	COG4464	protein tyrosine phosphatase activity
L6451_RS26575	COG0489	protein tyrosine kinase activity
L6451_RS26580	COG3944	biosynthesis protein
L6451_RS26585	COG0489	protein tyrosine kinase activity
L6451_RS26600	COG1609	Transcriptional regulator
L6451_RS26610	COG0739	heme binding
L6451_RS26625	COG3279	Response regulator of the LytR AlgR family
L6451_RS26630	COG2385	sporulation resulting in formation of a cellular spore
L6451_RS26645	COG4836	Membrane
L6451_RS26650	COG1007	ATP synthesis coupled electron transport
L6451_RS26660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L6451_RS26670	COG0839	Belongs to the complex I subunit 6 family
L6451_RS26690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L6451_RS26705	COG3300	MHYT domain
L6451_RS26705	COG5001	Diguanylate cyclase
L6451_RS26755	COG0356	it plays a direct role in the translocation of protons across the membrane
L6451_RS26790	COG0698	ribose 5-phosphate isomerase
L6451_RS26800	COG2190	(PTS) system
L6451_RS26805	COG2259	Doxx family
L6451_RS26810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L6451_RS26830	COG0009	L-threonylcarbamoyladenylate synthase
L6451_RS26845	COG2890	protein-(glutamine-N5) methyltransferase activity
L6451_RS26865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L6451_RS26870	COG1494	fructose-1,6-bisphosphatase
L6451_RS26890	COG4821	SIS domain
L6451_RS26910	COG1960	acyl-CoA dehydrogenase activity
L6451_RS26915	COG1960	acyl-CoA dehydrogenase activity
L6451_RS26920	COG1250	3-hydroxyacyl-CoA dehydrogenase
L6451_RS26925	COG0183	Belongs to the thiolase family
L6451_RS26930	COG2181	nitrate reductase activity
L6451_RS26930	COG0247	lactate metabolic process
L6451_RS26935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6451_RS26945	COG5001	Diguanylate cyclase
L6451_RS26945	COG3300	MHYT domain
L6451_RS26965	COG2197	response regulator
L6451_RS26970	COG4585	Histidine kinase
L6451_RS26975	COG0842	Transport permease protein
L6451_RS26980	COG1131	(ABC) transporter
L6451_RS26985	COG0024	Methionine aminopeptidase
L6451_RS26990	COG2234	aminopeptidase activity
L6451_RS27010	COG1595	DNA-templated transcription, initiation
L6451_RS27020	COG4506	Protein conserved in bacteria
L6451_RS27025	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6451_RS27040	COG0010	Belongs to the arginase family
L6451_RS27050	COG2814	Major facilitator Superfamily
L6451_RS27055	COG0789	Transcriptional regulator
L6451_RS27060	COG0584	glycerophosphoryl diester phosphodiesterase
L6451_RS27065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6451_RS27075	COG1994	Peptidase M50
L6451_RS27085	COG1078	dGTPase activity
L6451_RS27090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6451_RS27095	COG1120	ATPase activity
L6451_RS27100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS27105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6451_RS27125	COG0095	Lipoate-protein ligase
L6451_RS27130	COG0280	phosphate acetyltransferase
L6451_RS27145	COG3773	Cell wall hydrolase
L6451_RS27155	COG2363	Small membrane protein
L6451_RS27165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L6451_RS27170	COG2233	PERMEase
L6451_RS27175	COG0561	phosphatase activity
L6451_RS27180	COG2814	Major facilitator Superfamily
L6451_RS27190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6451_RS27195	COG1131	(ABC) transporter
L6451_RS27200	COG2755	lipolytic protein G-D-S-L family
L6451_RS27205	COG1609	Transcriptional regulator
L6451_RS27215	COG0460	homoserine dehydrogenase
L6451_RS27225	COG2873	o-acetylhomoserine
L6451_RS27230	COG1011	Hydrolase
L6451_RS27235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L6451_RS27245	COG2197	response regulator
L6451_RS27250	COG2203	Gaf domain
L6451_RS27250	COG4585	Histidine kinase
L6451_RS27255	COG0351	phosphomethylpyrimidine kinase
L6451_RS27260	COG3706	GGDEF domain
L6451_RS27265	COG2879	small protein
L6451_RS27270	COG1966	Carbon starvation protein
L6451_RS27275	COG3279	Response regulator of the LytR AlgR family
L6451_RS27280	COG0477	Major facilitator Superfamily
L6451_RS27305	COG0840	transmembrane signaling receptor activity
L6451_RS27315	COG1607	acyl-coa hydrolase
L6451_RS27320	COG1216	Glycosyl transferase, family 2
L6451_RS27330	COG0488	(ABC) transporter
L6451_RS27350	COG0463	Glycosyl transferase, family 2
L6451_RS27355	COG1309	transcriptional regulator
L6451_RS27360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L6451_RS27365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6451_RS27365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6451_RS27370	COG0628	permease
L6451_RS27385	COG3279	Response regulator of the LytR AlgR family
L6451_RS27390	COG3275	phosphorelay sensor kinase activity
L6451_RS27395	COG2814	Major facilitator Superfamily
L6451_RS27400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6451_RS27405	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
L6451_RS27410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6451_RS27460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L6451_RS27465	COG1272	protein, Hemolysin III
L6451_RS27495	COG1164	Oligoendopeptidase f
L6451_RS27505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6451_RS27535	COG4974	Belongs to the 'phage' integrase family
L6451_RS27595	COG1196	nuclear chromosome segregation
L6451_RS27615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6451_RS27620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L6451_RS27625	COG4853	Protein conserved in bacteria
L6451_RS27630	COG4863	YycH protein
L6451_RS27635	COG5002	protein histidine kinase activity
L6451_RS27640	COG0745	RESPONSE REGULATOR receiver
L6451_RS27670	COG0305	Participates in initiation and elongation during chromosome replication
L6451_RS27680	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L6451_RS27685	COG4241	membrane
L6451_RS27695	COG0629	single-stranded DNA binding
L6451_RS27705	COG0012	GTP binding
L6451_RS27710	COG4481	Protein conserved in bacteria
L6451_RS27715	COG0668	transmembrane transport
L6451_RS27725	COG1475	DNA binding
L6451_RS27730	COG1192	Involved in chromosome partitioning
L6451_RS27755	COG1847	R3H domain protein
L6451_RS27760	COG0706	membrane insertase activity
L6451_RS27770	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L6451_RS27775	COG3397	chitin binding
L6451_RS27840	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L6451_RS27855	COG2003	Belongs to the UPF0758 family
L6451_RS27885	COG0582	viral genome integration into host DNA
L6451_RS27890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L6451_RS27925	COG1396	sequence-specific DNA binding
L6451_RS27980	COG3344	reverse transcriptase
L6451_RS28000	COG3344	reverse transcriptase
L6451_RS28120	COG0457	Tetratricopeptide repeat
L6451_RS28135	COG4974	Belongs to the 'phage' integrase family
L6451_RS28170	COG0745	RESPONSE REGULATOR receiver
L6451_RS28175	COG4990	cell redox homeostasis
L6451_RS28180	COG1335	isochorismatase
L6451_RS28215	COG2918	glutathione biosynthetic process
L6451_RS28215	COG1181	Belongs to the D-alanine--D-alanine ligase family
L6451_RS28225	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L6451_RS28235	COG1733	regulation of RNA biosynthetic process
L6451_RS28255	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6451_RS28270	COG3708	Transcriptional regulator
L6451_RS28270	COG2207	Transcriptional regulator
L6451_RS28340	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L6451_RS28375	COG2002	toxin-antitoxin pair type II binding
L6451_RS28415	COG0776	regulation of translation
L6451_RS28445	COG2311	Membrane
L6451_RS28480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L6451_RS28485	COG1621	beta-fructofuranosidase activity
L6451_RS28490	COG1263	PTS System
L6451_RS28490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6451_RS28495	COG1609	Transcriptional regulator
L6451_RS29045	COG0640	Transcriptional regulator
L6451_RS29090	COG0791	NLP P60 protein
L6451_RS29090	COG1388	LysM domain
L6451_RS29090	COG3103	Sh3 type 3 domain protein