locus-tag	class	description
GE376_RS00010	COG0592	DNA-directed DNA polymerase activity
GE376_RS00015	COG2501	S4 domain
GE376_RS00025	COG0187	DNA topoisomerase II activity
GE376_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GE376_RS00065	COG0517	IMP dehydrogenase activity
GE376_RS00065	COG0516	GMP reductase activity
GE376_RS00070	COG1686	Belongs to the peptidase S11 family
GE376_RS00100	COG1428	Deoxynucleoside kinase
GE376_RS00105	COG1428	Deoxynucleoside kinase
GE376_RS00110	COG1335	isochorismatase
GE376_RS00115	COG0590	tRNA wobble adenosine to inosine editing
GE376_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GE376_RS00180	COG1982	Orn Lys Arg decarboxylase major
GE376_RS00190	COG0470	DNA polymerase III
GE376_RS00195	COG1774	PSP1 C-terminal conserved region
GE376_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GE376_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GE376_RS00220	COG2002	toxin-antitoxin pair type II binding
GE376_RS00230	COG0084	hydrolase, TatD family'
GE376_RS00250	COG4466	Protein conserved in bacteria
GE376_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GE376_RS00270	COG0251	oxidation-reduction process
GE376_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GE376_RS00305	COG2002	toxin-antitoxin pair type II binding
GE376_RS00310	COG2244	polysaccharide biosynthetic process
GE376_RS00315	COG3956	TIGRFAM MazG family protein
GE376_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GE376_RS00340	COG1098	S1 RNA binding domain
GE376_RS00355	COG2208	phosphoserine phosphatase activity
GE376_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GE376_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GE376_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GE376_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
GE376_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GE376_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GE376_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GE376_RS00420	COG1396	sequence-specific DNA binding
GE376_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE376_RS00515	COG3880	PFAM UvrB UvrC protein
GE376_RS00525	COG0542	response to heat
GE376_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GE376_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
GE376_RS00560	COG1045	serine acetyltransferase
GE376_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE376_RS00580	COG3688	RNA-binding protein containing a PIN domain
GE376_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GE376_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
GE376_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GE376_RS00620	COG0222	ribosome binding
GE376_RS00625	COG2813	Specifically methylates the guanine in position
GE376_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GE376_RS00640	COG1358	cellular component organization or biogenesis
GE376_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GE376_RS00665	COG0051	transcription antitermination factor activity, RNA binding
GE376_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GE376_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
GE376_RS00770	COG0201	protein transport
GE376_RS00780	COG0024	Methionine aminopeptidase
GE376_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GE376_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GE376_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_RS00855	COG0489	protein tyrosine kinase activity
GE376_RS00865	COG2194	sulfuric ester hydrolase activity
GE376_RS00870	COG0726	polysaccharide deacetylase
GE376_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GE376_RS00955	COG4856	YbbR-like protein
GE376_RS00995	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS01000	COG2011	ABC-type metal ion transport system permease component
GE376_RS01005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GE376_RS01010	COG1464	Belongs to the NlpA lipoprotein family
GE376_RS01015	COG0604	alcohol dehydrogenase
GE376_RS01025	COG0277	FAD linked oxidase domain protein
GE376_RS01030	COG2271	Major facilitator Superfamily
GE376_RS01040	COG2814	Major facilitator Superfamily
GE376_RS01060	COG0601	transmembrane transport
GE376_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_RS01070	COG0444	Belongs to the ABC transporter superfamily
GE376_RS01075	COG4608	Belongs to the ABC transporter superfamily
GE376_RS01080	COG4166	transmembrane transport
GE376_RS01095	COG4166	transmembrane transport
GE376_RS01100	COG4166	transmembrane transport
GE376_RS01105	COG0656	L-ascorbic acid biosynthetic process
GE376_RS01125	COG4149	molybdate abc transporter
GE376_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
GE376_RS01135	COG1910	domain protein
GE376_RS01150	COG0697	spore germination
GE376_RS01165	COG0204	Acyl-transferase
GE376_RS01175	COG1609	Transcriptional regulator
GE376_RS01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS01200	COG5298	Protein conserved in bacteria
GE376_RS01225	COG0488	(ABC) transporter
GE376_RS01235	COG0747	negative chemotaxis
GE376_RS01240	COG0601	transmembrane transport
GE376_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_RS01250	COG0444	Belongs to the ABC transporter superfamily
GE376_RS01255	COG4608	Belongs to the ABC transporter superfamily
GE376_RS01260	COG0561	phosphatase activity
GE376_RS01285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GE376_RS01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
GE376_RS01300	COG0531	amino acid
GE376_RS01305	COG2814	Major facilitator Superfamily
GE376_RS01315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE376_RS01325	COG4294	response to UV
GE376_RS01330	COG0705	Rhomboid family
GE376_RS01340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GE376_RS01345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GE376_RS01350	COG0864	Transcriptional regulator
GE376_RS01355	COG2337	Toxic component of a toxin-antitoxin (TA) module
GE376_RS01360	COG2183	response to ionizing radiation
GE376_RS01460	COG0802	atpase or kinase
GE376_RS01465	COG1214	PFAM Peptidase M22, glycoprotease
GE376_RS01470	COG0456	acetyltransferase
GE376_RS01480	COG0488	(ABC) transporter
GE376_RS01495	COG1266	CAAX protease self-immunity
GE376_RS01515	COG2252	PERMEase
GE376_RS01525	COG5002	protein histidine kinase activity
GE376_RS01550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GE376_RS01575	COG0506	proline dehydrogenase activity
GE376_RS01615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_RS01625	COG1215	transferase activity, transferring glycosyl groups
GE376_RS01645	COG0697	spore germination
GE376_RS01675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GE376_RS01680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GE376_RS01685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GE376_RS01695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GE376_RS01710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GE376_RS01720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GE376_RS01730	COG0151	Belongs to the GarS family
GE376_RS01740	COG0583	DNA-binding transcription factor activity
GE376_RS01765	COG0210	DNA helicase
GE376_RS01775	COG4851	CamS sex pheromone cAM373 precursor
GE376_RS01790	COG1335	isochorismatase
GE376_RS01800	COG2011	ABC-type metal ion transport system permease component
GE376_RS01805	COG1464	Belongs to the NlpA lipoprotein family
GE376_RS01820	COG0003	Pfam Anion-transporting ATPase
GE376_RS01825	COG1846	Transcriptional regulator
GE376_RS01830	COG4682	membrane
GE376_RS01850	COG1597	lipid kinase activity
GE376_RS01855	COG0546	phosphoglycolate phosphatase activity
GE376_RS01860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GE376_RS01870	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS01875	COG2076	Multidrug Resistance protein
GE376_RS01885	COG2309	aminopeptidase activity
GE376_RS01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS01910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GE376_RS01925	COG4807	Protein conserved in bacteria
GE376_RS01950	COG1757	Na H antiporter
GE376_RS01955	COG1473	amidohydrolase
GE376_RS01970	COG0450	alkyl hydroperoxide reductase
GE376_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS01995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS02000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS02005	COG0492	ferredoxin-NADP+ reductase activity
GE376_RS02015	COG0166	Belongs to the GPI family
GE376_RS02040	COG5002	protein histidine kinase activity
GE376_RS02060	COG3541	Predicted nucleotidyltransferase
GE376_RS02065	COG2814	Major facilitator Superfamily
GE376_RS02070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_RS02070	COG0723	plastoquinol--plastocyanin reductase activity
GE376_RS02080	COG0765	amino acid transport
GE376_RS02085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_RS02095	COG0840	transmembrane signaling receptor activity
GE376_RS02120	COG0549	Belongs to the carbamate kinase family
GE376_RS02125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_RS02135	COG0277	FAD linked oxidase domain protein
GE376_RS02140	COG0366	Alpha amylase catalytic
GE376_RS02145	COG1263	PTS System
GE376_RS02145	COG2190	(PTS) system
GE376_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_RS02175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GE376_RS02195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_RS02200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_RS02205	COG1116	anion transmembrane transporter activity
GE376_RS02210	COG0488	(ABC) transporter
GE376_RS02255	COG2270	Major facilitator Superfamily
GE376_RS02290	COG2310	stress, protein
GE376_RS02295	COG2310	stress, protein
GE376_RS02300	COG2310	stress, protein
GE376_RS02305	COG0861	Integral membrane protein TerC family
GE376_RS02315	COG3853	Toxic anion resistance protein (TelA)
GE376_RS02330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GE376_RS02340	COG1295	ribonuclease BN
GE376_RS02345	COG2217	Heavy metal translocating P-type atpase
GE376_RS02350	COG0697	spore germination
GE376_RS02370	COG0586	Pfam SNARE associated Golgi protein
GE376_RS02385	COG3871	stress protein (general stress protein 26)
GE376_RS02390	COG0387	Pfam Sodium calcium exchanger
GE376_RS02400	COG0535	radical SAM domain protein
GE376_RS02420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GE376_RS02425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GE376_RS02440	COG3829	transcription factor binding
GE376_RS02450	COG0833	amino acid
GE376_RS02455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE376_RS02480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_RS02480	COG1263	PTS System
GE376_RS02485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_RS02500	COG1216	Glycosyl transferase, family 2
GE376_RS02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GE376_RS02515	COG0463	Glycosyl transferase, family 2
GE376_RS02530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GE376_RS02550	COG1228	amidohydrolase
GE376_RS02555	COG1090	epimerase
GE376_RS02585	COG1988	membrane-bound metal-dependent
GE376_RS02590	COG1194	a g-specific adenine glycosylase
GE376_RS02610	COG3557	Belongs to the UPF0374 family
GE376_RS02615	COG1132	(ABC) transporter
GE376_RS02620	COG4129	membrane
GE376_RS02625	COG0069	glutamate synthase activity
GE376_RS02625	COG0070	glutamate synthase
GE376_RS02625	COG0067	glutamate synthase
GE376_RS02635	COG4555	ABC transporter
GE376_RS02655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GE376_RS02660	COG0735	belongs to the Fur family
GE376_RS02780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GE376_RS02805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GE376_RS02810	COG1716	ATPase activity
GE376_RS02810	COG5001	Diguanylate cyclase
GE376_RS02815	COG2766	serine protein kinase
GE376_RS02835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GE376_RS02845	COG1585	Membrane protein implicated in regulation of membrane protease activity
GE376_RS02850	COG2268	Band 7 protein
GE376_RS02860	COG3290	protein histidine kinase activity
GE376_RS02865	COG4565	transcriptional regulatory protein
GE376_RS02870	COG2851	Citrate transporter
GE376_RS02895	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GE376_RS02900	COG3842	ATPase activity
GE376_RS02905	COG1175	transmembrane transport
GE376_RS02910	COG0395	ABC-type sugar transport system, permease component
GE376_RS02920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GE376_RS02925	COG0745	RESPONSE REGULATOR receiver
GE376_RS02930	COG5002	protein histidine kinase activity
GE376_RS02940	COG4990	cell redox homeostasis
GE376_RS02950	COG3290	protein histidine kinase activity
GE376_RS02955	COG4565	transcriptional regulatory protein
GE376_RS02960	COG3493	citrate carrier protein
GE376_RS02965	COG0281	malic enzyme
GE376_RS02975	COG0697	spore germination
GE376_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS02990	COG5002	protein histidine kinase activity
GE376_RS02995	COG0745	RESPONSE REGULATOR receiver
GE376_RS03000	COG0454	-acetyltransferase
GE376_RS03000	COG0456	acetyltransferase
GE376_RS03005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GE376_RS03010	COG3383	formate dehydrogenase (NAD+) activity
GE376_RS03015	COG2427	Protein of unknown function (DUF1641)
GE376_RS03030	COG0531	amino acid
GE376_RS03035	COG0640	Transcriptional regulator
GE376_RS03040	COG2217	Heavy metal translocating P-type atpase
GE376_RS03050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GE376_RS03065	COG3227	Zinc metalloprotease (Elastase)
GE376_RS03085	COG2720	vancomycin resistance protein
GE376_RS03090	COG1316	TRANSCRIPTIONal
GE376_RS03095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS03100	COG0346	lactoylglutathione lyase activity
GE376_RS03105	COG1253	flavin adenine dinucleotide binding
GE376_RS03110	COG1027	Aspartate ammonia-lyase
GE376_RS03115	COG1620	l-lactate permease
GE376_RS03130	COG3104	oligopeptide transport
GE376_RS03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS03160	COG0156	8-amino-7-oxononanoate synthase activity
GE376_RS03165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_RS03175	COG4548	von Willebrand factor, type A
GE376_RS03180	COG0714	Associated with various cellular activities
GE376_RS03200	COG0531	amino acid
GE376_RS03205	COG2188	Transcriptional regulator
GE376_RS03210	COG1263	PTS System
GE376_RS03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_RS03215	COG0366	Alpha amylase catalytic
GE376_RS03230	COG0697	spore germination
GE376_RS03240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GE376_RS03245	COG1115	amino acid carrier protein
GE376_RS03250	COG1126	abc transporter atp-binding protein
GE376_RS03255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_RS03260	COG0765	amino acid transport
GE376_RS03265	COG0765	amino acid transport
GE376_RS03270	COG0833	amino acid
GE376_RS03285	COG1595	DNA-templated transcription, initiation
GE376_RS03295	COG2378	regulation of single-species biofilm formation
GE376_RS03300	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE376_RS03305	COG5002	protein histidine kinase activity
GE376_RS03320	COG0659	secondary active sulfate transmembrane transporter activity
GE376_RS03335	COG0747	negative chemotaxis
GE376_RS03345	COG0601	transmembrane transport
GE376_RS03350	COG4608	Belongs to the ABC transporter superfamily
GE376_RS03360	COG2271	Major facilitator Superfamily
GE376_RS03365	COG1846	Transcriptional regulator
GE376_RS03370	COG0477	Major facilitator Superfamily
GE376_RS03375	COG1609	Transcriptional regulator
GE376_RS03380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GE376_RS03395	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE376_RS03400	COG1879	ABC-type sugar transport system periplasmic component
GE376_RS03425	COG1063	alcohol dehydrogenase
GE376_RS03475	COG0840	transmembrane signaling receptor activity
GE376_RS03480	COG3584	3D domain protein
GE376_RS03480	COG1388	LysM domain
GE376_RS03485	COG1476	TRANSCRIPTIONal
GE376_RS03505	COG3104	oligopeptide transport
GE376_RS03510	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS03525	COG1113	amino acid transport
GE376_RS03530	COG2252	PERMEase
GE376_RS03545	COG2153	protein acetylation
GE376_RS03555	COG0569	domain protein
GE376_RS03555	COG0475	glutathione-regulated potassium exporter activity
GE376_RS03565	COG1845	cytochrome c oxidase, subunit III
GE376_RS03570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GE376_RS03580	COG0833	amino acid
GE376_RS03585	COG4990	cell redox homeostasis
GE376_RS03600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_RS03605	COG0697	spore germination
GE376_RS03610	COG0531	amino acid
GE376_RS03620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GE376_RS03625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GE376_RS03630	COG1918	ferrous iron import across plasma membrane
GE376_RS03630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GE376_RS03635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GE376_RS03640	COG0573	inorganic phosphate transmembrane transporter activity
GE376_RS03645	COG0581	inorganic phosphate transmembrane transporter activity
GE376_RS03655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GE376_RS03775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GE376_RS03795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GE376_RS03800	COG1116	anion transmembrane transporter activity
GE376_RS03805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_RS03810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_RS03815	COG0352	thiamine-phosphate diphosphorylase activity
GE376_RS03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_RS03825	COG2104	thiamine diphosphate biosynthetic process
GE376_RS03835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_RS03840	COG0351	phosphomethylpyrimidine kinase
GE376_RS03880	COG2205	protein histidine kinase activity
GE376_RS03885	COG2814	Major facilitator Superfamily
GE376_RS03890	COG1846	Transcriptional regulator
GE376_RS03905	COG2252	PERMEase
GE376_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS03970	COG0778	Nitroreductase
GE376_RS03975	COG2719	SpoVR family
GE376_RS03985	COG1414	Transcriptional regulator
GE376_RS04000	COG0446	pyridine nucleotide-disulphide oxidoreductase
GE376_RS04005	COG1937	Protein conserved in bacteria
GE376_RS04010	COG0425	Belongs to the sulfur carrier protein TusA family
GE376_RS04010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS04015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_RS04020	COG0425	Belongs to the sulfur carrier protein TusA family
GE376_RS04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_RS04035	COG2210	Belongs to the sulfur carrier protein TusA family
GE376_RS04040	COG0730	response to heat
GE376_RS04050	COG1316	TRANSCRIPTIONal
GE376_RS04055	COG0604	alcohol dehydrogenase
GE376_RS04060	COG1283	sodium-dependent phosphate transmembrane transporter activity
GE376_RS04075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS04075	COG3711	transcriptional antiterminator
GE376_RS04080	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE376_RS04085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE376_RS04105	COG1388	LysM domain
GE376_RS04105	COG3584	3D domain protein
GE376_RS04110	COG0577	efflux transmembrane transporter activity
GE376_RS04115	COG1136	(ABC) transporter
GE376_RS04125	COG5522	Integral membrane protein (intg_mem_TP0381)
GE376_RS04140	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS04145	COG3546	catalase activity
GE376_RS04180	COG0586	Pfam SNARE associated Golgi protein
GE376_RS04210	COG0531	amino acid
GE376_RS04215	COG0475	glutathione-regulated potassium exporter activity
GE376_RS04225	COG1737	Transcriptional regulator
GE376_RS04235	COG1263	PTS System
GE376_RS04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_RS04245	COG2259	Doxx family
GE376_RS04265	COG1522	sequence-specific DNA binding
GE376_RS04270	COG0165	Argininosuccinate lyase
GE376_RS04270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GE376_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS04290	COG2076	Multidrug Resistance protein
GE376_RS04295	COG1309	transcriptional regulator
GE376_RS04300	COG2814	Major facilitator Superfamily
GE376_RS04305	COG1733	regulation of RNA biosynthetic process
GE376_RS04320	COG4533	DNA binding
GE376_RS04325	COG2211	Major facilitator Superfamily
GE376_RS04335	COG0693	protein deglycase activity
GE376_RS04340	COG0753	catalase activity
GE376_RS04350	COG0531	amino acid
GE376_RS04365	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS04370	COG1132	(ABC) transporter
GE376_RS04375	COG1132	(ABC) transporter
GE376_RS04380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_RS04385	COG0765	amino acid transport
GE376_RS04390	COG1126	abc transporter atp-binding protein
GE376_RS04405	COG0189	ligase activity
GE376_RS04440	COG0028	Belongs to the TPP enzyme family
GE376_RS04445	COG3527	Alpha-acetolactate decarboxylase
GE376_RS04455	COG0561	phosphatase activity
GE376_RS04465	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS04465	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS04470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE376_RS04475	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS04490	COG0659	secondary active sulfate transmembrane transporter activity
GE376_RS04495	COG2244	polysaccharide biosynthetic process
GE376_RS04515	COG1024	Enoyl-CoA hydratase
GE376_RS04535	COG1363	Peptidase, m42
GE376_RS04575	COG0601	transmembrane transport
GE376_RS04580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_RS04585	COG0444	Belongs to the ABC transporter superfamily
GE376_RS04590	COG4608	Belongs to the ABC transporter superfamily
GE376_RS04620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS04645	COG0477	Major facilitator Superfamily
GE376_RS04650	COG3290	protein histidine kinase activity
GE376_RS04655	COG4565	transcriptional regulatory protein
GE376_RS04660	COG3181	Tripartite tricarboxylate transporter family receptor
GE376_RS04665	COG0494	nUDIX hydrolase
GE376_RS04680	COG0305	Participates in initiation and elongation during chromosome replication
GE376_RS04710	COG0477	Major facilitator Superfamily
GE376_RS04725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS04745	COG1073	alpha beta
GE376_RS04785	COG1183	phosphatidylcholine synthase activity
GE376_RS04800	COG2814	Major facilitator Superfamily
GE376_RS04805	COG0640	Transcriptional regulator
GE376_RS04815	COG2376	Dihydroxyacetone kinase
GE376_RS04825	COG2376	Dihydroxyacetone kinase
GE376_RS04860	COG0457	Tetratricopeptide repeat
GE376_RS04870	COG2373	Large extracellular alpha-helical protein
GE376_RS04900	COG0596	Alpha beta hydrolase
GE376_RS04935	COG3237	CsbD-like
GE376_RS04960	COG1191	sigma factor activity
GE376_RS04970	COG2208	phosphoserine phosphatase activity
GE376_RS04975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GE376_RS04980	COG5002	protein histidine kinase activity
GE376_RS04980	COG0784	Response regulator, receiver
GE376_RS04980	COG2205	protein histidine kinase activity
GE376_RS05015	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GE376_RS05035	COG0420	3'-5' exonuclease activity
GE376_RS05040	COG4717	serine-type aminopeptidase activity
GE376_RS05055	COG1280	lysine exporter protein (LysE YggA)
GE376_RS05060	COG0346	lactoylglutathione lyase activity
GE376_RS05065	COG0346	lactoylglutathione lyase activity
GE376_RS05070	COG0457	Tetratricopeptide repeat
GE376_RS05080	COG2267	carboxylic ester hydrolase activity
GE376_RS05105	COG2140	Oxalate decarboxylase
GE376_RS05110	COG3620	sequence-specific DNA binding
GE376_RS05115	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GE376_RS05120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE376_RS05130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GE376_RS05135	COG1695	Transcriptional regulator
GE376_RS05145	COG1595	DNA-templated transcription, initiation
GE376_RS05165	COG2409	Drug exporters of the RND superfamily
GE376_RS05165	COG1033	growth of symbiont in host cell
GE376_RS05170	COG3973	AAA domain
GE376_RS05200	COG4980	gas vesicle protein
GE376_RS05205	COG0537	adenosine 5'-monophosphoramidase activity
GE376_RS05210	COG1131	(ABC) transporter
GE376_RS05215	COG4473	ABC transporter
GE376_RS05275	COG1309	transcriptional regulator
GE376_RS05280	COG3402	PFAM membrane-flanked domain
GE376_RS05285	COG3428	Bacterial PH domain
GE376_RS05330	COG0697	spore germination
GE376_RS05335	COG3402	PFAM membrane-flanked domain
GE376_RS05340	COG3428	Bacterial PH domain
GE376_RS05345	COG2329	Antibiotic biosynthesis monooxygenase
GE376_RS05350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_RS05365	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GE376_RS05400	COG1309	transcriptional regulator
GE376_RS05405	COG1511	domain protein
GE376_RS05430	COG1609	Transcriptional regulator
GE376_RS05440	COG1234	tRNA 3'-trailer cleavage
GE376_RS05445	COG0095	Lipoate-protein ligase
GE376_RS05455	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS05465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GE376_RS05475	COG4208	sulfate ABC transporter
GE376_RS05495	COG1408	metallophosphoesterase
GE376_RS05505	COG1078	dGTPase activity
GE376_RS05515	COG1595	DNA-templated transcription, initiation
GE376_RS05520	COG3708	Transcriptional regulator
GE376_RS05520	COG2207	Transcriptional regulator
GE376_RS05530	COG2205	protein histidine kinase activity
GE376_RS05535	COG0745	RESPONSE REGULATOR receiver
GE376_RS05555	COG0501	Belongs to the peptidase M48B family
GE376_RS05560	COG0840	transmembrane signaling receptor activity
GE376_RS05565	COG3693	PFAM glycoside hydrolase, family 10
GE376_RS05575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GE376_RS05580	COG2224	Isocitrate lyase
GE376_RS05595	COG1278	Cold shock
GE376_RS05615	COG0398	Pfam SNARE associated Golgi protein
GE376_RS05635	COG0202	RNA polymerase activity
GE376_RS05675	COG0179	Fumarylacetoacetate (FAA) hydrolase
GE376_RS05700	COG0367	asparagine synthase
GE376_RS05710	COG0753	catalase activity
GE376_RS05715	COG0004	ammonium transporteR
GE376_RS05735	COG2996	Protein conserved in bacteria
GE376_RS05750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS05765	COG0561	phosphatase activity
GE376_RS05785	COG2267	carboxylic ester hydrolase activity
GE376_RS05800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE376_RS05805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE376_RS05810	COG5504	Zn-dependent protease
GE376_RS05820	COG0180	Tryptophanyl-tRNA synthetase
GE376_RS05830	COG4166	transmembrane transport
GE376_RS05835	COG0601	transmembrane transport
GE376_RS05840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GE376_RS05845	COG0444	Belongs to the ABC transporter superfamily
GE376_RS05850	COG4608	Belongs to the ABC transporter superfamily
GE376_RS05855	COG0534	Mate efflux family protein
GE376_RS05860	COG4166	transmembrane transport
GE376_RS05875	COG0861	Integral membrane protein TerC family
GE376_RS05885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_RS05895	COG1164	Oligoendopeptidase f
GE376_RS05905	COG2346	COG2346, Truncated hemoglobins
GE376_RS05910	COG4116	CYTH
GE376_RS05920	COG2357	RelA SpoT domain protein
GE376_RS05930	COG0564	pseudouridine synthase activity
GE376_RS05945	COG0772	Belongs to the SEDS family
GE376_RS05950	COG1216	Glycosyl transferase, family 2
GE376_RS05970	COG0463	Glycosyl transferase, family 2
GE376_RS05970	COG0457	Tetratricopeptide repeat
GE376_RS05990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GE376_RS06005	COG1091	dTDP-4-dehydrorhamnose reductase activity
GE376_RS06050	COG2153	protein acetylation
GE376_RS06060	COG2382	esterase
GE376_RS06080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_RS06090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GE376_RS06090	COG0512	Glutamine amidotransferase of anthranilate synthase
GE376_RS06125	COG1620	l-lactate permease
GE376_RS06130	COG5634	Uncharacterized conserved protein (DUF2278)
GE376_RS06145	COG4640	response to antibiotic
GE376_RS06170	COG2226	methyltransferase
GE376_RS06190	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE376_RS06200	COG1476	TRANSCRIPTIONal
GE376_RS06265	COG2226	methyltransferase
GE376_RS06275	COG1686	Belongs to the peptidase S11 family
GE376_RS06280	COG0681	Belongs to the peptidase S26 family
GE376_RS06315	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS06325	COG1176	ABC-type spermidine putrescine transport system, permease component I
GE376_RS06330	COG1177	transmembrane transport
GE376_RS06345	COG2409	Drug exporters of the RND superfamily
GE376_RS06355	COG0564	pseudouridine synthase activity
GE376_RS06365	COG2340	Cysteine-rich secretory protein family
GE376_RS06370	COG0247	lactate metabolic process
GE376_RS06375	COG0277	FAD linked oxidase domain protein
GE376_RS06380	COG3835	regulator
GE376_RS06390	COG0745	RESPONSE REGULATOR receiver
GE376_RS06395	COG5002	protein histidine kinase activity
GE376_RS06400	COG2186	Transcriptional regulator
GE376_RS06420	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GE376_RS06430	COG2116	formate transmembrane transporter activity
GE376_RS06435	COG0861	Integral membrane protein TerC family
GE376_RS06440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE376_RS06450	COG2030	dehydratase
GE376_RS06470	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS06475	COG3243	poly(R)-hydroxyalkanoic acid synthase
GE376_RS06485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE376_RS06495	COG1840	ABC-type Fe3 transport system, periplasmic component
GE376_RS06500	COG3842	ATPase activity
GE376_RS06525	COG1349	DNA-binding transcription factor activity
GE376_RS06535	COG0235	Class ii aldolase
GE376_RS06545	COG2861	carbohydrate metabolic process
GE376_RS06555	COG3852	Histidine kinase
GE376_RS06560	COG1846	Transcriptional regulator
GE376_RS06570	COG2318	DinB family
GE376_RS06575	COG5002	protein histidine kinase activity
GE376_RS06585	COG0720	synthase
GE376_RS06600	COG4873	Protein conserved in bacteria
GE376_RS06630	COG1780	Probably involved in ribonucleotide reductase function
GE376_RS06635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE376_RS06640	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GE376_RS06645	COG1725	Transcriptional regulator
GE376_RS06650	COG1131	(ABC) transporter
GE376_RS06660	COG1131	(ABC) transporter
GE376_RS06680	COG1522	sequence-specific DNA binding
GE376_RS06690	COG1335	isochorismatase
GE376_RS06700	COG1619	proteins homologs of microcin C7 resistance protein MccF
GE376_RS06705	COG2070	2-Nitropropane dioxygenase
GE376_RS06710	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GE376_RS06720	COG1696	Membrane protein involved in D-alanine export
GE376_RS06740	COG0716	FMN binding
GE376_RS06785	COG1846	Transcriptional regulator
GE376_RS06795	COG1301	dicarboxylic acid transport
GE376_RS06800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GE376_RS06805	COG4709	membrane
GE376_RS06810	COG3874	Sporulation protein YtfJ
GE376_RS06830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_RS06835	COG0028	Belongs to the TPP enzyme family
GE376_RS06840	COG0440	acetolactate synthase activity
GE376_RS06915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GE376_RS06930	COG1183	phosphatidylcholine synthase activity
GE376_RS06935	COG1368	sulfuric ester hydrolase activity
GE376_RS06945	COG0019	diaminopimelate decarboxylase activity
GE376_RS06965	COG0529	Catalyzes the synthesis of activated sulfate
GE376_RS06970	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_RS06990	COG1648	precorrin-2 dehydrogenase activity
GE376_RS06995	COG0733	neurotransmitter:sodium symporter activity
GE376_RS07015	COG1757	Na H antiporter
GE376_RS07030	COG4758	membrane
GE376_RS07035	COG4585	Histidine kinase
GE376_RS07040	COG2197	response regulator
GE376_RS07050	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS07060	COG2226	methyltransferase
GE376_RS07100	COG0730	response to heat
GE376_RS07105	COG0306	phosphate transporter
GE376_RS07110	COG1392	Phosphate transport regulator
GE376_RS07115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_RS07130	COG3852	Histidine kinase
GE376_RS07135	COG1801	Protein of unknown function DUF72
GE376_RS07145	COG0582	viral genome integration into host DNA
GE376_RS07150	COG5002	protein histidine kinase activity
GE376_RS07165	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GE376_RS07165	COG0392	lysyltransferase activity
GE376_RS07180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GE376_RS07185	COG1686	Belongs to the peptidase S11 family
GE376_RS07190	COG2715	membrane protein required for spore maturation
GE376_RS07195	COG0700	Nucleoside recognition
GE376_RS07200	COG1187	pseudouridine synthase activity
GE376_RS07210	COG1333	cytochrome c biogenesis protein
GE376_RS07215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GE376_RS07220	COG0745	RESPONSE REGULATOR receiver
GE376_RS07225	COG5002	protein histidine kinase activity
GE376_RS07230	COG2096	Adenosyltransferase
GE376_RS07245	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GE376_RS07250	COG1141	Ferredoxin
GE376_RS07260	COG0514	ATP-dependent DNA helicase (RecQ)
GE376_RS07265	COG1266	CAAX protease self-immunity
GE376_RS07275	COG1408	metallophosphoesterase
GE376_RS07280	COG0789	Transcriptional regulator
GE376_RS07290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GE376_RS07310	COG0492	ferredoxin-NADP+ reductase activity
GE376_RS07315	COG0252	asparaginase activity
GE376_RS07390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE376_RS07405	COG0142	geranyltranstransferase activity
GE376_RS07415	COG0142	geranyltranstransferase activity
GE376_RS07440	COG0457	Tetratricopeptide repeat
GE376_RS07460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GE376_RS07465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GE376_RS07465	COG2010	Cytochrome c
GE376_RS07470	COG4347	Protein of unknown function (DUF1405)
GE376_RS07485	COG2738	Putative neutral zinc metallopeptidase
GE376_RS07495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS07500	COG1694	Mazg nucleotide pyrophosphohydrolase
GE376_RS07520	COG0438	transferase activity, transferring glycosyl groups
GE376_RS07555	COG1199	ATP-dependent helicase activity
GE376_RS07555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GE376_RS07575	COG3935	DnaD domain protein
GE376_RS07580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GE376_RS07590	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE376_RS07590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_RS07645	COG0116	Belongs to the methyltransferase superfamily
GE376_RS07655	COG1199	ATP-dependent helicase activity
GE376_RS07660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GE376_RS07670	COG0024	Methionine aminopeptidase
GE376_RS07680	COG2233	PERMEase
GE376_RS07685	COG2311	Membrane
GE376_RS07690	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE376_RS07700	COG0456	acetyltransferase
GE376_RS07750	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE376_RS07765	COG3944	biosynthesis protein
GE376_RS07775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE376_RS07790	COG1215	transferase activity, transferring glycosyl groups
GE376_RS07795	COG0438	transferase activity, transferring glycosyl groups
GE376_RS07810	COG0454	-acetyltransferase
GE376_RS07830	COG0328	RNA-DNA hybrid ribonuclease activity
GE376_RS07865	COG3403	YqcI/YcgG family
GE376_RS07870	COG1280	lysine exporter protein (LysE YggA)
GE376_RS07890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_RS07895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE376_RS07905	COG0475	glutathione-regulated potassium exporter activity
GE376_RS07910	COG4978	Transcriptional regulator
GE376_RS07910	COG0789	Transcriptional regulator
GE376_RS07920	COG2323	membrane
GE376_RS07925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GE376_RS07985	COG1923	regulation of RNA biosynthetic process
GE376_RS07995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GE376_RS08000	COG1360	Flagellar Motor Protein
GE376_RS08005	COG2201	protein-glutamate methylesterase activity
GE376_RS08010	COG0643	Histidine kinase
GE376_RS08010	COG2198	Histidine kinase
GE376_RS08015	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_RS08015	COG1776	CheC inhibitor of MCP methylation
GE376_RS08030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GE376_RS08050	COG1256	bacterial-type flagellum assembly
GE376_RS08055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE376_RS08060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GE376_RS08075	COG1815	bacterial-type flagellum-dependent cell motility
GE376_RS08080	COG1558	bacterial-type flagellum-dependent cell motility
GE376_RS08090	COG1766	The M ring may be actively involved in energy transduction
GE376_RS08095	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_RS08105	COG1157	protein secretion by the type III secretion system
GE376_RS08125	COG1749	Flagellar hook protein flgE
GE376_RS08140	COG0784	Response regulator, receiver
GE376_RS08140	COG0835	chemotaxis
GE376_RS08150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE376_RS08155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GE376_RS08160	COG0741	lytic transglycosylase activity
GE376_RS08170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_RS08175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GE376_RS08175	COG1776	CheC inhibitor of MCP methylation
GE376_RS08185	COG1338	Plays a role in the flagellum-specific transport system
GE376_RS08190	COG1987	bacterial-type flagellum assembly
GE376_RS08200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GE376_RS08205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GE376_RS08210	COG1419	protein localization to endoplasmic reticulum
GE376_RS08215	COG4786	Flagellar basal body rod
GE376_RS08225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GE376_RS08260	COG2329	Antibiotic biosynthesis monooxygenase
GE376_RS08290	COG0583	DNA-binding transcription factor activity
GE376_RS08295	COG3842	ATPase activity
GE376_RS08310	COG1234	tRNA 3'-trailer cleavage
GE376_RS08375	COG0367	asparagine synthase
GE376_RS08405	COG1802	Transcriptional regulator
GE376_RS08410	COG0697	spore germination
GE376_RS08420	COG0523	cobalamin synthesis protein
GE376_RS08425	COG0701	Predicted permease
GE376_RS08440	COG1757	Na H antiporter
GE376_RS08445	COG0789	Transcriptional regulator
GE376_RS08470	COG0534	Mate efflux family protein
GE376_RS08475	COG3340	Belongs to the peptidase S51 family
GE376_RS08495	COG0785	Cytochrome C biogenesis protein
GE376_RS08500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS08530	COG2733	membrane
GE376_RS08565	COG1131	(ABC) transporter
GE376_RS08580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_RS08585	COG0528	UMP kinase activity
GE376_RS08595	COG1027	Aspartate ammonia-lyase
GE376_RS08600	COG0281	malic enzyme
GE376_RS08605	COG4191	Histidine kinase
GE376_RS08610	COG0784	Response regulator, receiver
GE376_RS08615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE376_RS08675	COG1695	Transcriptional regulator
GE376_RS08685	COG0477	Major facilitator Superfamily
GE376_RS08700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE376_RS08705	COG2223	nitrite transmembrane transporter activity
GE376_RS08710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_RS08730	COG0733	neurotransmitter:sodium symporter activity
GE376_RS08740	COG5566	PFAM Mor transcription activator
GE376_RS08745	COG2323	membrane
GE376_RS08765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE376_RS08775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_RS08780	COG0028	Belongs to the TPP enzyme family
GE376_RS08800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GE376_RS08825	COG2814	Major facilitator Superfamily
GE376_RS08830	COG3384	dioxygenase
GE376_RS08840	COG3279	Response regulator of the LytR AlgR family
GE376_RS08845	COG0427	acetyl-CoA hydrolase
GE376_RS08865	COG2814	Major facilitator Superfamily
GE376_RS08870	COG1309	transcriptional regulator
GE376_RS08875	COG4166	transmembrane transport
GE376_RS08920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS08925	COG0745	RESPONSE REGULATOR receiver
GE376_RS08945	COG1914	H( )-stimulated, divalent metal cation uptake system
GE376_RS08960	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GE376_RS08965	COG0531	amino acid
GE376_RS08990	COG2309	aminopeptidase activity
GE376_RS09005	COG0456	acetyltransferase
GE376_RS09015	COG1266	CAAX protease self-immunity
GE376_RS09020	COG1309	transcriptional regulator
GE376_RS09025	COG2390	Transcriptional regulator
GE376_RS09035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS09040	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GE376_RS09050	COG4846	Membrane protein involved in cytochrome C biogenesis
GE376_RS09070	COG0583	DNA-binding transcription factor activity
GE376_RS09085	COG0006	proline dipeptidase activity
GE376_RS09095	COG2132	Multicopper oxidase
GE376_RS09105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE376_RS09125	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS09135	COG1276	copper resistance
GE376_RS09135	COG2372	response to copper ion
GE376_RS09140	COG4549	nuclear export factor GLE1
GE376_RS09145	COG0697	spore germination
GE376_RS09150	COG0583	DNA-binding transcription factor activity
GE376_RS09155	COG1959	2 iron, 2 sulfur cluster binding
GE376_RS09160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GE376_RS09165	COG0778	Nitroreductase
GE376_RS09175	COG0628	permease
GE376_RS09185	COG1231	oxidoreductase activity
GE376_RS09190	COG0523	cobalamin synthesis protein
GE376_RS09200	COG0411	ABC transporter
GE376_RS09220	COG0583	DNA-binding transcription factor activity
GE376_RS09230	COG1942	4-Oxalocrotonate Tautomerase
GE376_RS09250	COG1271	oxidase subunit
GE376_RS09255	COG1294	oxidase, subunit
GE376_RS09260	COG4988	ABC transporter
GE376_RS09265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GE376_RS09275	COG1216	Glycosyl transferase, family 2
GE376_RS09315	COG1686	Belongs to the peptidase S11 family
GE376_RS09330	COG0791	NLP P60 protein
GE376_RS09330	COG1388	LysM domain
GE376_RS09340	COG1132	(ABC) transporter
GE376_RS09345	COG0745	RESPONSE REGULATOR receiver
GE376_RS09350	COG5002	protein histidine kinase activity
GE376_RS09360	COG0300	oxidoreductase activity
GE376_RS09365	COG4122	O-methyltransferase activity
GE376_RS09395	COG0460	homoserine dehydrogenase
GE376_RS09420	COG1316	TRANSCRIPTIONal
GE376_RS09430	COG0745	RESPONSE REGULATOR receiver
GE376_RS09435	COG5002	protein histidine kinase activity
GE376_RS09450	COG1285	pathogenesis
GE376_RS09455	COG1247	-acetyltransferase
GE376_RS09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE376_RS09485	COG1082	Xylose isomerase domain protein TIM barrel
GE376_RS09495	COG2814	Major facilitator Superfamily
GE376_RS09500	COG1279	arginine transmembrane transporter activity
GE376_RS09505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS09515	COG1752	Esterase of the alpha-beta hydrolase superfamily
GE376_RS09550	COG0577	efflux transmembrane transporter activity
GE376_RS09555	COG2002	toxin-antitoxin pair type II binding
GE376_RS09560	COG1404	Belongs to the peptidase S8 family
GE376_RS09565	COG0640	Transcriptional regulator
GE376_RS09570	COG0667	Aldo Keto reductase
GE376_RS09575	COG2814	Major facilitator Superfamily
GE376_RS09600	COG0840	transmembrane signaling receptor activity
GE376_RS09615	COG3949	Membrane
GE376_RS09620	COG0783	Belongs to the Dps family
GE376_RS09635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_RS09645	COG1231	oxidoreductase activity
GE376_RS09650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS09655	COG4989	oxidoreductase activity
GE376_RS09660	COG0523	cobalamin synthesis protein
GE376_RS09665	COG0456	acetyltransferase
GE376_RS09670	COG0803	Belongs to the bacterial solute-binding protein 9 family
GE376_RS09675	COG0702	epimerase
GE376_RS09685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GE376_RS09695	COG4166	transmembrane transport
GE376_RS09720	COG5337	Spore coat protein CotH
GE376_RS09725	COG1051	belongs to the nudix hydrolase family
GE376_RS09730	COG0586	Pfam SNARE associated Golgi protein
GE376_RS09735	COG2244	polysaccharide biosynthetic process
GE376_RS09745	COG0701	Predicted permease
GE376_RS09750	COG3689	TIGRFAM TIGR03943 family protein
GE376_RS09755	COG1607	acyl-coa hydrolase
GE376_RS09765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_RS09780	COG0702	epimerase
GE376_RS09785	COG2839	Protein conserved in bacteria
GE376_RS09790	COG1253	flavin adenine dinucleotide binding
GE376_RS09815	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS09820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GE376_RS09840	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_RS09850	COG1876	peptidase activity
GE376_RS09865	COG2211	Major facilitator Superfamily
GE376_RS09880	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_RS09890	COG0561	phosphatase activity
GE376_RS09895	COG1846	Transcriptional regulator
GE376_RS09900	COG2814	Major facilitator Superfamily
GE376_RS09910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GE376_RS09915	COG4106	trans-aconitate 2-methyltransferase activity
GE376_RS09930	COG1819	glycosyl
GE376_RS09935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS09940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS09970	COG0456	acetyltransferase
GE376_RS10025	COG3874	Sporulation protein YtfJ
GE376_RS10050	COG2226	methyltransferase
GE376_RS10070	COG1082	Xylose isomerase domain protein TIM barrel
GE376_RS10075	COG0346	lactoylglutathione lyase activity
GE376_RS10085	COG0604	alcohol dehydrogenase
GE376_RS10090	COG1595	DNA-templated transcription, initiation
GE376_RS10105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GE376_RS10105	COG0426	domain, Protein
GE376_RS10115	COG0386	Belongs to the glutathione peroxidase family
GE376_RS10120	COG1305	Transglutaminase-like
GE376_RS10125	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GE376_RS10130	COG0714	Associated with various cellular activities
GE376_RS10135	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GE376_RS10140	COG1140	nitrate reductase beta subunit
GE376_RS10145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GE376_RS10150	COG2181	nitrate reductase activity
GE376_RS10155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_RS10160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GE376_RS10165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_RS10170	COG0303	'Molybdopterin
GE376_RS10175	COG0314	molybdopterin synthase activity
GE376_RS10185	COG2223	nitrite transmembrane transporter activity
GE376_RS10200	COG1648	precorrin-2 dehydrogenase activity
GE376_RS10210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GE376_RS10210	COG1587	Uroporphyrinogen-III synthase
GE376_RS10215	COG2146	nitrite reductase [NAD(P)H] activity
GE376_RS10220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_RS10225	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GE376_RS10260	COG2359	stage V sporulation protein S
GE376_RS10290	COG5444	nuclease activity
GE376_RS10300	COG2856	Zn peptidase
GE376_RS10330	COG1396	sequence-specific DNA binding
GE376_RS10400	COG0582	viral genome integration into host DNA
GE376_RS10410	COG1278	Cold shock
GE376_RS10435	COG0582	viral genome integration into host DNA
GE376_RS10450	COG5484	DNA packaging
GE376_RS10455	COG1783	phage Terminase large subunit
GE376_RS10470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GE376_RS10600	COG0457	Tetratricopeptide repeat
GE376_RS10620	COG1418	mRNA catabolic process
GE376_RS10625	COG0488	(ABC) transporter
GE376_RS10640	COG0629	single-stranded DNA binding
GE376_RS10650	COG1413	lyase activity
GE376_RS10665	COG2136	Putative SAM-dependent methyltransferase
GE376_RS10665	COG2521	methyltransferase
GE376_RS10670	COG0018	arginyl-trna synthetase
GE376_RS10710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GE376_RS10715	COG0017	Asparaginyl-tRNA synthetase
GE376_RS10735	COG1674	ftsk spoiiie
GE376_RS10805	COG0733	neurotransmitter:sodium symporter activity
GE376_RS10830	COG2610	gluconate transmembrane transporter activity
GE376_RS10840	COG1794	racemase activity, acting on amino acids and derivatives
GE376_RS10850	COG0456	acetyltransferase
GE376_RS10860	COG3655	Transcriptional regulator
GE376_RS10865	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GE376_RS10875	COG1131	(ABC) transporter
GE376_RS10880	COG4473	ABC transporter
GE376_RS10890	COG0546	phosphoglycolate phosphatase activity
GE376_RS10905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_RS10920	COG0768	penicillin binding
GE376_RS10930	COG0204	Acyl-transferase
GE376_RS10935	COG1272	protein, Hemolysin III
GE376_RS10945	COG0805	protein transport
GE376_RS10955	COG1307	EDD domain protein, DegV family
GE376_RS10965	COG1999	signal sequence binding
GE376_RS10970	COG0071	Belongs to the small heat shock protein (HSP20) family
GE376_RS10975	COG0367	asparagine synthase
GE376_RS10990	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_RS10995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS11000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GE376_RS11020	COG1335	isochorismatase
GE376_RS11030	COG0668	transmembrane transport
GE376_RS11035	COG4585	Histidine kinase
GE376_RS11035	COG2203	Gaf domain
GE376_RS11040	COG2197	response regulator
GE376_RS11045	COG1737	Transcriptional regulator
GE376_RS11050	COG0384	phenazine biosynthesis protein PhzF
GE376_RS11055	COG1064	alcohol dehydrogenase
GE376_RS11070	COG1070	Carbohydrate kinase
GE376_RS11080	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GE376_RS11115	COG0517	IMP dehydrogenase activity
GE376_RS11115	COG1125	glycine betaine transport
GE376_RS11120	COG1174	glycine betaine transport
GE376_RS11155	COG1253	flavin adenine dinucleotide binding
GE376_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS11165	COG5506	Protein of unknown function (DUF1694)
GE376_RS11180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE376_RS11185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GE376_RS11190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GE376_RS11195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE376_RS11200	COG0456	acetyltransferase
GE376_RS11205	COG3829	transcription factor binding
GE376_RS11210	COG1509	lysine 2,3-aminomutase activity
GE376_RS11245	COG0515	serine threonine protein kinase
GE376_RS11245	COG3064	Membrane
GE376_RS11245	COG4991	sh3 domain protein
GE376_RS11250	COG4326	sporulation control protein
GE376_RS11255	COG0671	phosphoesterase, PA-phosphatase related
GE376_RS11260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE376_RS11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS11340	COG0300	oxidoreductase activity
GE376_RS11360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_RS11360	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE376_RS11370	COG2814	Major facilitator Superfamily
GE376_RS11375	COG4841	protein insertion into membrane
GE376_RS11380	COG0372	Belongs to the citrate synthase family
GE376_RS11385	COG2079	MmgE PrpD family protein
GE376_RS11390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GE376_RS11395	COG1960	acyl-CoA dehydrogenase activity
GE376_RS11400	COG2084	Dehydrogenase
GE376_RS11410	COG1280	lysine exporter protein (LysE YggA)
GE376_RS11415	COG1024	Enoyl-CoA hydratase
GE376_RS11430	COG0420	3'-5' exonuclease activity
GE376_RS11435	COG0419	ATPase involved in DNA repair
GE376_RS11465	COG2223	nitrite transmembrane transporter activity
GE376_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS11475	COG1169	isochorismate synthase
GE376_RS11480	COG1021	2,3-dihydroxybenzoate-AMP ligase
GE376_RS11485	COG1535	isochorismatase
GE376_RS11485	COG3433	isochorismatase activity
GE376_RS11490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_RS11495	COG3251	PFAM MbtH domain protein
GE376_RS11500	COG2814	Major facilitator Superfamily
GE376_RS11515	COG0776	regulation of translation
GE376_RS11525	COG2318	DinB family
GE376_RS11535	COG1115	amino acid carrier protein
GE376_RS11555	COG1187	pseudouridine synthase activity
GE376_RS11560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE376_RS11565	COG1136	(ABC) transporter
GE376_RS11575	COG2814	Major facilitator Superfamily
GE376_RS11590	COG0028	Belongs to the TPP enzyme family
GE376_RS11600	COG1234	tRNA 3'-trailer cleavage
GE376_RS11625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_RS11640	COG1846	Transcriptional regulator
GE376_RS11650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS11685	COG1247	-acetyltransferase
GE376_RS11710	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GE376_RS11720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS11750	COG0583	DNA-binding transcription factor activity
GE376_RS11755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GE376_RS11775	COG0583	DNA-binding transcription factor activity
GE376_RS11780	COG2258	MOSC domain
GE376_RS11795	COG1132	(ABC) transporter
GE376_RS11800	COG1132	(ABC) transporter
GE376_RS11840	COG0582	viral genome integration into host DNA
GE376_RS11870	COG5484	DNA packaging
GE376_RS11885	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS11915	COG1396	sequence-specific DNA binding
GE376_RS11950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE376_RS11955	COG1595	DNA-templated transcription, initiation
GE376_RS11975	COG1649	PFAM Uncharacterised BCR, COG1649
GE376_RS12000	COG2971	BadF BadG BcrA BcrD
GE376_RS12020	COG1846	Transcriptional regulator
GE376_RS12035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS12055	COG1309	transcriptional regulator
GE376_RS12070	COG3615	Tellurite resistance protein tehB
GE376_RS12070	COG0500	methyltransferase
GE376_RS12085	COG3961	Belongs to the TPP enzyme family
GE376_RS12090	COG1846	Transcriptional regulator
GE376_RS12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
GE376_RS12145	COG2002	toxin-antitoxin pair type II binding
GE376_RS12155	COG0730	response to heat
GE376_RS12160	COG0110	maltose O-acetyltransferase activity
GE376_RS12165	COG1686	Belongs to the peptidase S11 family
GE376_RS12180	COG2814	Major facilitator Superfamily
GE376_RS12215	COG1115	amino acid carrier protein
GE376_RS12225	COG4191	Histidine kinase
GE376_RS12230	COG0784	Response regulator, receiver
GE376_RS12235	COG0697	spore germination
GE376_RS12240	COG0531	amino acid
GE376_RS12250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_RS12255	COG0531	amino acid
GE376_RS12260	COG0322	excinuclease ABC activity
GE376_RS12275	COG2207	Transcriptional regulator
GE376_RS12300	COG5002	protein histidine kinase activity
GE376_RS12365	COG1760	l-serine dehydratase
GE376_RS12370	COG1760	l-serine dehydratase
GE376_RS12375	COG0814	amino acid
GE376_RS12385	COG0840	transmembrane signaling receptor activity
GE376_RS12405	COG1309	transcriptional regulator
GE376_RS12435	COG4224	UPF0291 protein
GE376_RS12440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_RS12445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GE376_RS12450	COG1278	Cold shock
GE376_RS12465	COG1329	Transcriptional regulator
GE376_RS12500	COG1280	lysine exporter protein (LysE YggA)
GE376_RS12515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_RS12535	COG0768	penicillin binding
GE376_RS12540	COG1595	DNA-templated transcription, initiation
GE376_RS12550	COG0768	penicillin binding
GE376_RS12555	COG0768	penicillin binding
GE376_RS12565	COG1408	metallophosphoesterase
GE376_RS12575	COG1131	(ABC) transporter
GE376_RS12585	COG1309	transcriptional regulator
GE376_RS12600	COG1960	acyl-CoA dehydrogenase activity
GE376_RS12605	COG0439	Biotin carboxylase
GE376_RS12610	COG0511	ligase activity, forming carbon-carbon bonds
GE376_RS12615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GE376_RS12620	COG1024	Enoyl-CoA hydratase
GE376_RS12625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GE376_RS12630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE376_RS12665	COG1686	Belongs to the peptidase S11 family
GE376_RS12705	COG3227	Zinc metalloprotease (Elastase)
GE376_RS12710	COG2207	Transcriptional regulator
GE376_RS12740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GE376_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS12755	COG1733	regulation of RNA biosynthetic process
GE376_RS12800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS12810	COG2368	4-hydroxyphenylacetate
GE376_RS12825	COG1063	alcohol dehydrogenase
GE376_RS12835	COG2323	membrane
GE376_RS12845	COG0693	protein deglycase activity
GE376_RS12855	COG3386	PFAM SMP-30 Gluconolaconase
GE376_RS12865	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GE376_RS12870	COG3773	Cell wall hydrolase
GE376_RS12880	COG0745	RESPONSE REGULATOR receiver
GE376_RS12885	COG2205	protein histidine kinase activity
GE376_RS12895	COG0488	(ABC) transporter
GE376_RS12910	COG1136	(ABC) transporter
GE376_RS12915	COG0577	efflux transmembrane transporter activity
GE376_RS12935	COG0460	homoserine dehydrogenase
GE376_RS12940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS12950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GE376_RS12975	COG0582	viral genome integration into host DNA
GE376_RS12990	COG1396	sequence-specific DNA binding
GE376_RS13010	COG2002	toxin-antitoxin pair type II binding
GE376_RS13075	COG0582	viral genome integration into host DNA
GE376_RS13115	COG4626	Terminase
GE376_RS13115	COG1802	Transcriptional regulator
GE376_RS13125	COG0740	serine-type endopeptidase activity
GE376_RS13210	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS13265	COG2124	cytochrome p450
GE376_RS13300	COG0561	phosphatase activity
GE376_RS13305	COG5002	protein histidine kinase activity
GE376_RS13310	COG0768	penicillin binding
GE376_RS13320	COG1819	glycosyl
GE376_RS13325	COG1794	racemase activity, acting on amino acids and derivatives
GE376_RS13350	COG2205	protein histidine kinase activity
GE376_RS13355	COG0582	viral genome integration into host DNA
GE376_RS13415	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE376_RS13425	COG0745	RESPONSE REGULATOR receiver
GE376_RS13430	COG5002	protein histidine kinase activity
GE376_RS13435	COG0604	alcohol dehydrogenase
GE376_RS13440	COG0671	phosphoesterase, PA-phosphatase related
GE376_RS13445	COG0768	penicillin binding
GE376_RS13500	COG2814	Major facilitator Superfamily
GE376_RS13515	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_RS13535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS13540	COG0697	spore germination
GE376_RS13575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_RS13580	COG2223	nitrite transmembrane transporter activity
GE376_RS13595	COG0592	DNA-directed DNA polymerase activity
GE376_RS13635	COG3878	Protein conserved in bacteria
GE376_RS13660	COG4667	esterase of the alpha-beta hydrolase superfamily
GE376_RS13700	COG0322	excinuclease ABC activity
GE376_RS13740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_RS13765	COG1011	Hydrolase
GE376_RS13770	COG0745	RESPONSE REGULATOR receiver
GE376_RS13775	COG5002	protein histidine kinase activity
GE376_RS13790	COG1522	sequence-specific DNA binding
GE376_RS13805	COG1136	(ABC) transporter
GE376_RS13810	COG0577	efflux transmembrane transporter activity
GE376_RS13815	COG1073	alpha beta
GE376_RS13825	COG1523	belongs to the glycosyl hydrolase 13 family
GE376_RS13830	COG3227	Zinc metalloprotease (Elastase)
GE376_RS13835	COG0737	Belongs to the 5'-nucleotidase family
GE376_RS13850	COG0201	protein transport
GE376_RS13865	COG0697	spore germination
GE376_RS13870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS13880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GE376_RS13910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS13925	COG2959	enzyme of heme biosynthesis
GE376_RS13965	COG1309	transcriptional regulator
GE376_RS13995	COG3284	Transcriptional regulator
GE376_RS14010	COG1349	DNA-binding transcription factor activity
GE376_RS14025	COG1959	2 iron, 2 sulfur cluster binding
GE376_RS14040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE376_RS14045	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE376_RS14050	COG0022	dehydrogenase e1 component
GE376_RS14055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE376_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS14095	COG4176	ABC-type proline glycine betaine transport system permease component
GE376_RS14100	COG0517	IMP dehydrogenase activity
GE376_RS14100	COG4175	Glycine betaine
GE376_RS14130	COG2153	protein acetylation
GE376_RS14135	COG3397	chitin binding
GE376_RS14140	COG1819	glycosyl
GE376_RS14155	COG2205	protein histidine kinase activity
GE376_RS14160	COG2226	methyltransferase
GE376_RS14165	COG2315	Protein conserved in bacteria
GE376_RS14210	COG3973	AAA domain
GE376_RS14235	COG0514	ATP-dependent DNA helicase (RecQ)
GE376_RS14265	COG4637	Psort location Cytoplasmic, score
GE376_RS14285	COG3397	chitin binding
GE376_RS14300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GE376_RS14305	COG1115	amino acid carrier protein
GE376_RS14310	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS14315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GE376_RS14325	COG3938	Belongs to the proline racemase family
GE376_RS14330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_RS14375	COG1078	dGTPase activity
GE376_RS14380	COG0586	Pfam SNARE associated Golgi protein
GE376_RS14390	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GE376_RS14395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS14400	COG4166	transmembrane transport
GE376_RS14410	COG4948	Mandelate Racemase Muconate Lactonizing
GE376_RS14425	COG0667	Aldo Keto reductase
GE376_RS14470	COG3850	Histidine kinase
GE376_RS14470	COG5002	protein histidine kinase activity
GE376_RS14475	COG0745	RESPONSE REGULATOR receiver
GE376_RS14520	COG1307	EDD domain protein, DegV family
GE376_RS14560	COG2814	Major facilitator Superfamily
GE376_RS14570	COG1664	Polymer-forming cytoskeletal
GE376_RS14575	COG0789	Transcriptional regulator
GE376_RS14580	COG4533	DNA binding
GE376_RS14585	COG2814	Major facilitator Superfamily
GE376_RS14585	COG0477	Major facilitator Superfamily
GE376_RS14610	COG2261	transglycosylase associated protein
GE376_RS14625	COG2226	methyltransferase
GE376_RS14660	COG0436	Aminotransferase
GE376_RS14665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GE376_RS14675	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GE376_RS14690	COG1131	(ABC) transporter
GE376_RS14740	COG0628	permease
GE376_RS14750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_RS14755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_RS14760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_RS14800	COG2746	aminoglycoside 3-N-acetyltransferase activity
GE376_RS14810	COG0697	spore germination
GE376_RS14840	COG4912	Dna alkylation repair
GE376_RS14845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_RS14850	COG0346	lactoylglutathione lyase activity
GE376_RS14880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS14885	COG0861	Integral membrane protein TerC family
GE376_RS14890	COG1368	sulfuric ester hydrolase activity
GE376_RS14895	COG0488	(ABC) transporter
GE376_RS14900	COG1033	growth of symbiont in host cell
GE376_RS14900	COG2409	Drug exporters of the RND superfamily
GE376_RS14905	COG1309	transcriptional regulator
GE376_RS14910	COG1051	belongs to the nudix hydrolase family
GE376_RS14925	COG0287	Prephenate dehydrogenase
GE376_RS14940	COG1605	Chorismate mutase
GE376_RS14940	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GE376_RS14990	COG3584	3D domain protein
GE376_RS14990	COG1388	LysM domain
GE376_RS15005	COG0277	FAD linked oxidase domain protein
GE376_RS15030	COG1879	ABC-type sugar transport system periplasmic component
GE376_RS15035	COG1172	Belongs to the binding-protein-dependent transport system permease family
GE376_RS15050	COG2390	Transcriptional regulator
GE376_RS15055	COG1070	Carbohydrate kinase
GE376_RS15080	COG2329	Antibiotic biosynthesis monooxygenase
GE376_RS15095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS15110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_RS15115	COG4187	Peptidase family M20/M25/M40
GE376_RS15120	COG1414	Transcriptional regulator
GE376_RS15125	COG0833	amino acid
GE376_RS15140	COG3239	Fatty acid desaturase
GE376_RS15150	COG2720	vancomycin resistance protein
GE376_RS15155	COG1785	Belongs to the alkaline phosphatase family
GE376_RS15165	COG3655	Transcriptional regulator
GE376_RS15190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS15195	COG0346	lactoylglutathione lyase activity
GE376_RS15215	COG0714	Associated with various cellular activities
GE376_RS15235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GE376_RS15240	COG0753	catalase activity
GE376_RS15275	COG0778	Nitroreductase
GE376_RS15280	COG1846	Transcriptional regulator
GE376_RS15315	COG1725	Transcriptional regulator
GE376_RS15340	COG0456	acetyltransferase
GE376_RS15355	COG0697	spore germination
GE376_RS15360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS15400	COG0730	response to heat
GE376_RS15405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS15410	COG0833	amino acid
GE376_RS15420	COG4335	DNA alkylation repair
GE376_RS15430	COG5002	protein histidine kinase activity
GE376_RS15435	COG0745	RESPONSE REGULATOR receiver
GE376_RS15445	COG1136	(ABC) transporter
GE376_RS15445	COG0577	efflux transmembrane transporter activity
GE376_RS15475	COG0768	penicillin binding
GE376_RS15510	COG1984	allophanate hydrolase subunit 2
GE376_RS15515	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GE376_RS15520	COG1414	Transcriptional regulator
GE376_RS15530	COG3142	Participates in the control of copper homeostasis
GE376_RS15535	COG0640	Transcriptional regulator
GE376_RS15545	COG1960	acyl-CoA dehydrogenase activity
GE376_RS15570	COG0542	response to heat
GE376_RS15590	COG3314	Sporulation integral membrane protein YlbJ
GE376_RS15610	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GE376_RS15635	COG3848	Pyruvate phosphate dikinase
GE376_RS15635	COG0574	Belongs to the PEP-utilizing enzyme family
GE376_RS15640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS15660	COG1063	alcohol dehydrogenase
GE376_RS15670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE376_RS15680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GE376_RS15695	COG0737	Belongs to the 5'-nucleotidase family
GE376_RS15700	COG2267	carboxylic ester hydrolase activity
GE376_RS15705	COG1335	isochorismatase
GE376_RS15725	COG0583	DNA-binding transcription factor activity
GE376_RS15730	COG1846	Transcriptional regulator
GE376_RS15740	COG0598	Magnesium transport protein CorA
GE376_RS15780	COG0814	amino acid
GE376_RS15785	COG0697	spore germination
GE376_RS15805	COG0415	Belongs to the DNA photolyase family
GE376_RS15820	COG0288	reversible hydration of carbon dioxide
GE376_RS15830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GE376_RS15835	COG5609	conserved protein (DUF2294)
GE376_RS15845	COG0456	acetyltransferase
GE376_RS15850	COG1575	Belongs to the MenA family. Type 1 subfamily
GE376_RS15875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS15885	COG0798	PFAM Bile acid sodium symporter
GE376_RS15890	COG0346	lactoylglutathione lyase activity
GE376_RS15895	COG0640	Transcriptional regulator
GE376_RS15905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GE376_RS15915	COG2814	Major facilitator Superfamily
GE376_RS15925	COG3320	Male sterility
GE376_RS15925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE376_RS15930	COG1309	transcriptional regulator
GE376_RS15975	COG2814	Major facilitator Superfamily
GE376_RS15980	COG1309	transcriptional regulator
GE376_RS15985	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS15990	COG1522	sequence-specific DNA binding
GE376_RS16005	COG0346	lactoylglutathione lyase activity
GE376_RS16055	COG0814	amino acid
GE376_RS16075	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS16075	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS16080	COG0583	DNA-binding transcription factor activity
GE376_RS16135	COG0745	RESPONSE REGULATOR receiver
GE376_RS16140	COG3850	Histidine kinase
GE376_RS16140	COG5002	protein histidine kinase activity
GE376_RS16180	COG1136	(ABC) transporter
GE376_RS16215	COG2814	Major facilitator Superfamily
GE376_RS16230	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GE376_RS16245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GE376_RS16265	COG0577	efflux transmembrane transporter activity
GE376_RS16285	COG3850	Histidine kinase
GE376_RS16285	COG5002	protein histidine kinase activity
GE376_RS16295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS16320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GE376_RS16370	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS16370	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS16390	COG1876	peptidase activity
GE376_RS16395	COG2843	Capsule synthesis protein
GE376_RS16405	COG0477	Major facilitator Superfamily
GE376_RS16420	COG1846	Transcriptional regulator
GE376_RS16425	COG2814	Major facilitator Superfamily
GE376_RS16435	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GE376_RS16440	COG1131	(ABC) transporter
GE376_RS16460	COG2031	fatty acid transporter
GE376_RS16470	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE376_RS16525	COG1288	antiporter activity
GE376_RS16530	COG2356	endonuclease I
GE376_RS16560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GE376_RS16580	COG1733	regulation of RNA biosynthetic process
GE376_RS16585	COG0778	Nitroreductase
GE376_RS16615	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS16625	COG1131	(ABC) transporter
GE376_RS16655	COG1011	Hydrolase
GE376_RS16660	COG2365	Tyrosine phosphatase family
GE376_RS16685	COG0346	lactoylglutathione lyase activity
GE376_RS16690	COG1940	carbohydrate kinase activity
GE376_RS16700	COG0110	maltose O-acetyltransferase activity
GE376_RS16715	COG0628	permease
GE376_RS16770	COG1253	flavin adenine dinucleotide binding
GE376_RS16775	COG0789	Transcriptional regulator
GE376_RS16785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GE376_RS16810	COG0697	spore germination
GE376_RS16820	COG1357	PFAM Pentapeptide repeats (8 copies)
GE376_RS16825	COG3813	Protein conserved in bacteria
GE376_RS16830	COG2706	6-phosphogluconolactonase activity
GE376_RS16835	COG1070	Carbohydrate kinase
GE376_RS16850	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GE376_RS16855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GE376_RS16860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GE376_RS16865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GE376_RS16870	COG0604	alcohol dehydrogenase
GE376_RS16875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_RS16890	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS16905	COG0840	transmembrane signaling receptor activity
GE376_RS16915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_RS16915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_RS16920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GE376_RS16920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GE376_RS16925	COG1733	regulation of RNA biosynthetic process
GE376_RS16940	COG0656	L-ascorbic acid biosynthetic process
GE376_RS16945	COG2814	Major facilitator Superfamily
GE376_RS16970	COG2824	Alkylphosphonate utilization operon protein PhnA
GE376_RS16975	COG0659	secondary active sulfate transmembrane transporter activity
GE376_RS16990	COG0814	amino acid
GE376_RS17025	COG1733	regulation of RNA biosynthetic process
GE376_RS17030	COG2188	Transcriptional regulator
GE376_RS17035	COG0673	inositol 2-dehydrogenase activity
GE376_RS17040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GE376_RS17045	COG1733	regulation of RNA biosynthetic process
GE376_RS17050	COG1733	regulation of RNA biosynthetic process
GE376_RS17075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS17100	COG0384	phenazine biosynthesis protein PhzF
GE376_RS17105	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS17110	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE376_RS17115	COG1733	regulation of RNA biosynthetic process
GE376_RS17130	COG0726	polysaccharide deacetylase
GE376_RS17140	COG1191	sigma factor activity
GE376_RS17150	COG1280	lysine exporter protein (LysE YggA)
GE376_RS17210	COG1151	hydroxylamine reductase activity
GE376_RS17220	COG3757	hydrolase, family 25
GE376_RS17220	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS17255	COG2072	flavoprotein involved in K transport
GE376_RS17290	COG1113	amino acid transport
GE376_RS17295	COG2814	Major facilitator Superfamily
GE376_RS17325	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GE376_RS17330	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE376_RS17345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS17350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS17355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS17360	COG3739	integral membrane protein
GE376_RS17390	COG0583	DNA-binding transcription factor activity
GE376_RS17410	COG1193	negative regulation of DNA recombination
GE376_RS17425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GE376_RS17430	COG1164	Oligoendopeptidase f
GE376_RS17455	COG3781	membrane
GE376_RS17470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_RS17495	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_RS17540	COG0640	Transcriptional regulator
GE376_RS17545	COG0604	alcohol dehydrogenase
GE376_RS17555	COG0457	Tetratricopeptide repeat
GE376_RS17565	COG2808	Putative FMN-binding domain
GE376_RS17570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE376_RS17585	COG0277	FAD linked oxidase domain protein
GE376_RS17610	COG1183	phosphatidylcholine synthase activity
GE376_RS17625	COG1252	NADH dehydrogenase
GE376_RS17635	COG0823	Involved in the tonB-independent uptake of proteins
GE376_RS17640	COG3397	chitin binding
GE376_RS17650	COG0697	spore germination
GE376_RS17670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GE376_RS17680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GE376_RS17690	COG0457	Tetratricopeptide repeat
GE376_RS17710	COG1404	Belongs to the peptidase S8 family
GE376_RS17740	COG0488	(ABC) transporter
GE376_RS17745	COG1309	transcriptional regulator
GE376_RS17760	COG1876	peptidase activity
GE376_RS17785	COG3852	Histidine kinase
GE376_RS17795	COG1285	pathogenesis
GE376_RS17805	COG2514	catechol 2,3-dioxygenase activity
GE376_RS17810	COG2720	vancomycin resistance protein
GE376_RS17845	COG0716	FMN binding
GE376_RS17855	COG1051	belongs to the nudix hydrolase family
GE376_RS17875	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS17885	COG0165	Argininosuccinate lyase
GE376_RS17900	COG4145	pantothenate transmembrane transporter activity
GE376_RS17910	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS17925	COG1657	PFAM Prenyltransferase squalene oxidase
GE376_RS17930	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GE376_RS17935	COG2962	Rard protein
GE376_RS17940	COG3326	Membrane
GE376_RS17955	COG0489	protein tyrosine kinase activity
GE376_RS17965	COG0314	molybdopterin synthase activity
GE376_RS17970	COG0303	'Molybdopterin
GE376_RS17975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_RS17980	COG2116	formate transmembrane transporter activity
GE376_RS17990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GE376_RS17995	COG5609	conserved protein (DUF2294)
GE376_RS18000	COG2427	Protein of unknown function (DUF1641)
GE376_RS18005	COG3383	formate dehydrogenase (NAD+) activity
GE376_RS18010	COG0697	spore germination
GE376_RS18025	COG0531	amino acid
GE376_RS18060	COG2226	methyltransferase
GE376_RS18065	COG4166	transmembrane transport
GE376_RS18070	COG4166	transmembrane transport
GE376_RS18075	COG4166	transmembrane transport
GE376_RS18080	COG1316	TRANSCRIPTIONal
GE376_RS18090	COG1595	DNA-templated transcription, initiation
GE376_RS18100	COG1131	(ABC) transporter
GE376_RS18120	COG0673	inositol 2-dehydrogenase activity
GE376_RS18125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GE376_RS18130	COG0187	DNA topoisomerase II activity
GE376_RS18135	COG1832	CoA-binding protein
GE376_RS18140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_RS18145	COG0745	RESPONSE REGULATOR receiver
GE376_RS18165	COG4841	protein insertion into membrane
GE376_RS18170	COG0824	Thioesterase
GE376_RS18195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS18205	COG1132	(ABC) transporter
GE376_RS18210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GE376_RS18240	COG2211	Major facilitator Superfamily
GE376_RS18250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GE376_RS18265	COG0183	Belongs to the thiolase family
GE376_RS18270	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS18275	COG1268	BioY protein
GE376_RS18280	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS18290	COG5002	protein histidine kinase activity
GE376_RS18305	COG1136	(ABC) transporter
GE376_RS18320	COG1131	(ABC) transporter
GE376_RS18405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS18415	COG5002	protein histidine kinase activity
GE376_RS18420	COG0400	carboxylic ester hydrolase activity
GE376_RS18425	COG0346	lactoylglutathione lyase activity
GE376_RS18430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GE376_RS18435	COG0069	glutamate synthase activity
GE376_RS18440	COG1902	pentaerythritol trinitrate reductase activity
GE376_RS18445	COG1329	Transcriptional regulator
GE376_RS18450	COG0010	Belongs to the arginase family
GE376_RS18475	COG2226	methyltransferase
GE376_RS18500	COG4846	Membrane protein involved in cytochrome C biogenesis
GE376_RS18505	COG0785	Cytochrome C biogenesis protein
GE376_RS18515	COG1473	amidohydrolase
GE376_RS18525	COG1131	(ABC) transporter
GE376_RS18540	COG0583	DNA-binding transcription factor activity
GE376_RS18550	COG1346	cytolysis
GE376_RS18565	COG0730	response to heat
GE376_RS18590	COG1132	(ABC) transporter
GE376_RS18595	COG1132	(ABC) transporter
GE376_RS18630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_RS18635	COG0737	Belongs to the 5'-nucleotidase family
GE376_RS18645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GE376_RS18665	COG1695	Transcriptional regulator
GE376_RS18670	COG0174	glutamine synthetase
GE376_RS18675	COG0789	Transcriptional regulator
GE376_RS18680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GE376_RS18685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GE376_RS18690	COG2860	membrane
GE376_RS18695	COG0464	growth
GE376_RS18725	COG3584	3D domain protein
GE376_RS18725	COG1388	LysM domain
GE376_RS18735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_RS18735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS18735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_RS18740	COG1105	Belongs to the carbohydrate kinase PfkB family
GE376_RS18745	COG1349	DNA-binding transcription factor activity
GE376_RS18750	COG1979	alcohol dehydrogenase
GE376_RS18755	COG2322	membrane
GE376_RS18765	COG1113	amino acid transport
GE376_RS18775	COG1408	metallophosphoesterase
GE376_RS18780	COG2116	formate transmembrane transporter activity
GE376_RS18795	COG2217	Heavy metal translocating P-type atpase
GE376_RS18800	COG2608	mercury ion transmembrane transporter activity
GE376_RS18805	COG1937	Protein conserved in bacteria
GE376_RS18815	COG2819	hydrolase of the alpha beta superfamily
GE376_RS18820	COG1120	ATPase activity
GE376_RS18825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS18830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS18835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS18840	COG0708	Exodeoxyribonuclease III
GE376_RS18845	COG2169	Transcriptional regulator
GE376_RS18850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GE376_RS18855	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GE376_RS18865	COG2364	Membrane
GE376_RS18880	COG2267	carboxylic ester hydrolase activity
GE376_RS18885	COG3300	MHYT domain
GE376_RS18885	COG5001	Diguanylate cyclase
GE376_RS18905	COG1086	Polysaccharide biosynthesis protein
GE376_RS18925	COG1346	cytolysis
GE376_RS18935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS18945	COG2188	Transcriptional regulator
GE376_RS18950	COG2723	6-phospho-beta-galactosidase activity
GE376_RS18960	COG1404	Belongs to the peptidase S8 family
GE376_RS18965	COG3773	Cell wall hydrolase
GE376_RS18975	COG1368	sulfuric ester hydrolase activity
GE376_RS18980	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GE376_RS19005	COG4550	Control of competence regulator ComK, YlbF/YmcA
GE376_RS19015	COG1013	pyruvate-flavodoxin oxidoreductase activity
GE376_RS19020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GE376_RS19020	COG0674	pyruvate-flavodoxin oxidoreductase activity
GE376_RS19030	COG2359	stage V sporulation protein S
GE376_RS19035	COG1692	metallophosphoesterase
GE376_RS19055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GE376_RS19060	COG1426	Protein conserved in bacteria
GE376_RS19075	COG0300	oxidoreductase activity
GE376_RS19080	COG0612	Peptidase, M16
GE376_RS19085	COG0612	Peptidase, M16
GE376_RS19090	COG1079	Belongs to the binding-protein-dependent transport system permease family
GE376_RS19095	COG4603	Belongs to the binding-protein-dependent transport system permease family
GE376_RS19100	COG3845	ABC transporter
GE376_RS19105	COG1744	ABC transporter substrate-binding protein PnrA-like
GE376_RS19110	COG2188	Transcriptional regulator
GE376_RS19125	COG0740	serine-type endopeptidase activity
GE376_RS19130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE376_RS19140	COG0527	aspartate kinase activity
GE376_RS19145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GE376_RS19150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE376_RS19165	COG5444	nuclease activity
GE376_RS19175	COG0582	viral genome integration into host DNA
GE376_RS19225	COG0305	Participates in initiation and elongation during chromosome replication
GE376_RS19290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE376_RS19295	COG1873	PFAM PRC-barrel domain
GE376_RS19300	COG0612	Peptidase, M16
GE376_RS19305	COG0726	polysaccharide deacetylase
GE376_RS19320	COG0196	riboflavin kinase activity
GE376_RS19330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GE376_RS19335	COG1550	Protein conserved in bacteria
GE376_RS19345	COG1358	cellular component organization or biogenesis
GE376_RS19350	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GE376_RS19355	COG0195	Participates in both transcription termination and antitermination
GE376_RS19375	COG0750	zinc metalloprotease
GE376_RS19385	COG4589	Belongs to the CDS family
GE376_RS19430	COG4974	Belongs to the 'phage' integrase family
GE376_RS19440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GE376_RS19445	COG0758	DNA mediated transformation
GE376_RS19450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GE376_RS19490	COG1837	Belongs to the UPF0109 family
GE376_RS19500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GE376_RS19510	COG0552	protein localization to endoplasmic reticulum
GE376_RS19515	COG1196	nuclear chromosome segregation
GE376_RS19525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE376_RS19530	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS19535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GE376_RS19550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GE376_RS19555	COG1461	Dihydroxyacetone kinase
GE376_RS19560	COG1302	Protein conserved in bacteria
GE376_RS19575	COG1564	THIamine pyrophosphokinase
GE376_RS19580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GE376_RS19590	COG0515	serine threonine protein kinase
GE376_RS19590	COG2815	serine threonine protein kinase
GE376_RS19595	COG0631	protein serine/threonine phosphatase activity
GE376_RS19605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GE376_RS19605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GE376_RS19620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GE376_RS19625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GE376_RS19645	COG1561	YicC-like family, N-terminal region
GE376_RS19650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GE376_RS19665	COG0006	proline dipeptidase activity
GE376_RS19685	COG3069	C4-dicarboxylate transmembrane transporter activity
GE376_RS19750	COG0564	pseudouridine synthase activity
GE376_RS19770	COG3599	regulation of cell shape
GE376_RS19775	COG2302	S4 RNA-binding domain
GE376_RS19780	COG0762	integral membrane protein
GE376_RS19790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GE376_RS19800	COG1873	PFAM PRC-barrel domain
GE376_RS19805	COG1191	sigma factor activity
GE376_RS19810	COG1191	sigma factor activity
GE376_RS19820	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GE376_RS19825	COG0849	cell division
GE376_RS19845	COG0772	Belongs to the SEDS family
GE376_RS19865	COG0768	penicillin binding
GE376_RS19870	COG0768	penicillin binding
GE376_RS19890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GE376_RS19905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GE376_RS19910	COG1399	metal-binding, possibly nucleic acid-binding protein
GE376_RS19920	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE376_RS19925	COG1752	Esterase of the alpha-beta hydrolase superfamily
GE376_RS19930	COG3314	Sporulation integral membrane protein YlbJ
GE376_RS19940	COG0742	ribosomal rna small subunit methyltransferase
GE376_RS19960	COG3679	Belongs to the UPF0342 family
GE376_RS19965	COG0406	alpha-ribazole phosphatase activity
GE376_RS19980	COG2340	Cysteine-rich secretory protein family
GE376_RS19995	COG3336	cytochrome c oxidase
GE376_RS20030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GE376_RS20035	COG0772	Belongs to the SEDS family
GE376_RS20045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GE376_RS20050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GE376_RS20060	COG4896	Protein conserved in bacteria
GE376_RS20075	COG1217	gtp-binding protein TYPA
GE376_RS20085	COG0483	inositol monophosphate 1-phosphatase activity
GE376_RS20105	COG1982	Orn Lys Arg decarboxylase major
GE376_RS20155	COG0022	dehydrogenase e1 component
GE376_RS20160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE376_RS20175	COG0561	phosphatase activity
GE376_RS20185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GE376_RS20190	COG0569	domain protein
GE376_RS20210	COG0583	DNA-binding transcription factor activity
GE376_RS20215	COG0517	IMP dehydrogenase activity
GE376_RS20225	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GE376_RS20230	COG4703	Protein of unknown function (DUF1797)
GE376_RS20245	COG2200	EAL domain
GE376_RS20250	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS20255	COG1408	metallophosphoesterase
GE376_RS20300	COG2814	Major facilitator Superfamily
GE376_RS20320	COG3209	COG3209 Rhs family protein
GE376_RS20330	COG2205	protein histidine kinase activity
GE376_RS20340	COG0436	Aminotransferase
GE376_RS20345	COG1609	Transcriptional regulator
GE376_RS20350	COG3833	ABC-type maltose transport systems, permease component
GE376_RS20355	COG1175	transmembrane transport
GE376_RS20360	COG2182	Extracellular solute-binding protein
GE376_RS20370	COG0366	Alpha amylase catalytic
GE376_RS20375	COG3842	ATPase activity
GE376_RS20415	COG0183	Belongs to the thiolase family
GE376_RS20445	COG1695	Transcriptional regulator
GE376_RS20450	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS20470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GE376_RS20475	COG0436	Aminotransferase
GE376_RS20510	COG2084	Dehydrogenase
GE376_RS20520	COG2199	diguanylate cyclase activity
GE376_RS20525	COG0778	Nitroreductase
GE376_RS20550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GE376_RS20550	COG2190	(PTS) system
GE376_RS20550	COG1263	PTS System
GE376_RS20555	COG3711	transcriptional antiterminator
GE376_RS20565	COG2188	Transcriptional regulator
GE376_RS20575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GE376_RS20600	COG1547	Domain of unknown function (DUF309)
GE376_RS20605	COG0456	acetyltransferase
GE376_RS20610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GE376_RS20615	COG4086	secreted protein
GE376_RS20620	COG0561	phosphatase activity
GE376_RS20625	COG0697	spore germination
GE376_RS20640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE376_RS20665	COG0733	neurotransmitter:sodium symporter activity
GE376_RS20685	COG1686	Belongs to the peptidase S11 family
GE376_RS20690	COG1725	Transcriptional regulator
GE376_RS20695	COG1131	(ABC) transporter
GE376_RS20715	COG1846	Transcriptional regulator
GE376_RS20730	COG0598	Magnesium transport protein CorA
GE376_RS20755	COG4974	Belongs to the 'phage' integrase family
GE376_RS20765	COG0735	belongs to the Fur family
GE376_RS20770	COG1300	Membrane
GE376_RS20790	COG0667	Aldo Keto reductase
GE376_RS20795	COG0656	L-ascorbic acid biosynthetic process
GE376_RS20800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE376_RS20800	COG0456	acetyltransferase
GE376_RS20810	COG4085	toxin activity
GE376_RS20810	COG1525	nuclease
GE376_RS20810	COG0737	Belongs to the 5'-nucleotidase family
GE376_RS20820	COG0596	Alpha beta hydrolase
GE376_RS20825	COG2056	Na+-H+ antiporter family
GE376_RS20830	COG1609	Transcriptional regulator
GE376_RS20835	COG0456	acetyltransferase
GE376_RS20840	COG1073	alpha beta
GE376_RS20855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_RS20855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GE376_RS20860	COG0307	riboflavin synthase, alpha
GE376_RS20890	COG2226	methyltransferase
GE376_RS20890	COG1073	alpha beta
GE376_RS20905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GE376_RS20915	COG1757	Na H antiporter
GE376_RS20920	COG0737	Belongs to the 5'-nucleotidase family
GE376_RS20930	COG1522	sequence-specific DNA binding
GE376_RS20975	COG0300	oxidoreductase activity
GE376_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS20985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_RS20990	COG1760	l-serine dehydratase
GE376_RS20995	COG1760	l-serine dehydratase
GE376_RS21025	COG1285	pathogenesis
GE376_RS21035	COG2195	Cleaves the N-terminal amino acid of tripeptides
GE376_RS21040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS21055	COG1376	ErfK ybiS ycfS ynhG family protein
GE376_RS21060	COG4129	membrane
GE376_RS21065	COG1126	abc transporter atp-binding protein
GE376_RS21070	COG0765	amino acid transport
GE376_RS21075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GE376_RS21095	COG2323	membrane
GE376_RS21100	COG0772	Belongs to the SEDS family
GE376_RS21105	COG0508	dehydrogenase complex catalyzes the overall conversion of
GE376_RS21110	COG0022	dehydrogenase e1 component
GE376_RS21115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GE376_RS21120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GE376_RS21135	COG0280	phosphate acetyltransferase
GE376_RS21140	COG3290	protein histidine kinase activity
GE376_RS21140	COG3829	transcription factor binding
GE376_RS21150	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_RS21155	COG3093	addiction module antidote protein HigA
GE376_RS21170	COG0750	zinc metalloprotease
GE376_RS21175	COG0497	DNA recombination
GE376_RS21185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GE376_RS21195	COG0142	geranyltranstransferase activity
GE376_RS21220	COG1302	Protein conserved in bacteria
GE376_RS21225	COG0439	Biotin carboxylase
GE376_RS21230	COG0511	ligase activity, forming carbon-carbon bonds
GE376_RS21275	COG3854	ATPases associated with a variety of cellular activities
GE376_RS21300	COG0006	proline dipeptidase activity
GE376_RS21315	COG3872	metal-dependent enzyme
GE376_RS21325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GE376_RS21360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_RS21370	COG1609	Transcriptional regulator
GE376_RS21380	COG2076	Multidrug Resistance protein
GE376_RS21385	COG2076	Multidrug Resistance protein
GE376_RS21420	COG1725	Transcriptional regulator
GE376_RS21450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE376_RS21515	COG1459	type II secretion system
GE376_RS21520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GE376_RS21585	COG1410	methionine synthase
GE376_RS21585	COG0646	methionine synthase
GE376_RS21590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GE376_RS21590	COG0646	methionine synthase
GE376_RS21595	COG0626	cystathionine gamma-synthase activity
GE376_RS21600	COG0626	cystathionine gamma-synthase activity
GE376_RS21620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS21630	COG1940	carbohydrate kinase activity
GE376_RS21635	COG4483	Protein conserved in bacteria
GE376_RS21640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GE376_RS21645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GE376_RS21650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GE376_RS21660	COG0704	Plays a role in the regulation of phosphate uptake
GE376_RS21670	COG0573	inorganic phosphate transmembrane transporter activity
GE376_RS21675	COG0573	inorganic phosphate transmembrane transporter activity
GE376_RS21680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GE376_RS21685	COG0768	penicillin binding
GE376_RS21690	COG0477	Major facilitator Superfamily
GE376_RS21695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GE376_RS21705	COG5521	maltodextrose utilization protein MalA
GE376_RS21720	COG0735	belongs to the Fur family
GE376_RS21725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GE376_RS21730	COG1121	(ABC) transporter
GE376_RS21735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS21765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GE376_RS21770	COG2384	SAM-dependent methyltransferase
GE376_RS21780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GE376_RS21785	COG0358	DNA primase activity
GE376_RS21795	COG0517	IMP dehydrogenase activity
GE376_RS21810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GE376_RS21815	COG0295	cytidine deaminase activity
GE376_RS21820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GE376_RS21830	COG1480	7TM receptor with intracellular HD hydrolase
GE376_RS21835	COG1702	phosphate starvation-inducible protein PhoH
GE376_RS21855	COG1610	YqeY-like protein
GE376_RS21860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GE376_RS21865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GE376_RS21870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GE376_RS21900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GE376_RS21905	COG1733	regulation of RNA biosynthetic process
GE376_RS21930	COG1466	dna polymerase III delta subunit
GE376_RS21940	COG2333	competence protein COMEC
GE376_RS21940	COG0658	competence protein
GE376_RS21945	COG2131	deaminase
GE376_RS21950	COG1555	photosystem II stabilization
GE376_RS21950	COG1596	polysaccharide export
GE376_RS21955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GE376_RS21960	COG2226	methyltransferase
GE376_RS21965	COG0799	negative regulation of ribosome biogenesis
GE376_RS21970	COG1713	HD superfamily hydrolase involved in NAD metabolism
GE376_RS21980	COG1534	Rna-binding protein
GE376_RS21990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GE376_RS21995	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GE376_RS22020	COG1595	DNA-templated transcription, initiation
GE376_RS22030	COG0778	Nitroreductase
GE376_RS22035	COG2357	RelA SpoT domain protein
GE376_RS22045	COG1785	Belongs to the alkaline phosphatase family
GE376_RS22055	COG2267	carboxylic ester hydrolase activity
GE376_RS22090	COG1404	Belongs to the peptidase S8 family
GE376_RS22095	COG3186	Phenylalanine-4-hydroxylase
GE376_RS22105	COG2514	catechol 2,3-dioxygenase activity
GE376_RS22110	COG2259	Doxx family
GE376_RS22150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS22160	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS22160	COG1454	alcohol dehydrogenase
GE376_RS22165	COG0626	cystathionine gamma-synthase activity
GE376_RS22170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GE376_RS22195	COG0768	penicillin binding
GE376_RS22210	COG0826	peptidase U32
GE376_RS22215	COG0826	peptidase U32
GE376_RS22220	COG4122	O-methyltransferase activity
GE376_RS22225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GE376_RS22240	COG4472	Bacterial protein of unknown function (DUF965)
GE376_RS22255	COG0628	permease
GE376_RS22275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GE376_RS22290	COG1104	cysteine desulfurase activity
GE376_RS22295	COG1959	2 iron, 2 sulfur cluster binding
GE376_RS22300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GE376_RS22310	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GE376_RS22330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GE376_RS22340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GE376_RS22340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GE376_RS22345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GE376_RS22350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE376_RS22350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GE376_RS22360	COG2244	polysaccharide biosynthetic process
GE376_RS22365	COG2323	membrane
GE376_RS22375	COG1862	Preprotein translocase
GE376_RS22405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GE376_RS22435	COG0157	Belongs to the NadC ModD family
GE376_RS22440	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GE376_RS22445	COG1104	cysteine desulfurase activity
GE376_RS22450	COG1827	regulation of RNA biosynthetic process
GE376_RS22455	COG2258	MOSC domain
GE376_RS22460	COG0077	Prephenate dehydratase
GE376_RS22465	COG0577	efflux transmembrane transporter activity
GE376_RS22470	COG0577	efflux transmembrane transporter activity
GE376_RS22475	COG1136	(ABC) transporter
GE376_RS22480	COG5002	protein histidine kinase activity
GE376_RS22485	COG0745	RESPONSE REGULATOR receiver
GE376_RS22495	COG3290	protein histidine kinase activity
GE376_RS22505	COG2868	ribosomal protein
GE376_RS22515	COG1530	ribonuclease E activity
GE376_RS22520	COG1994	Peptidase M50
GE376_RS22525	COG0739	heme binding
GE376_RS22530	COG2894	cell division
GE376_RS22550	COG1077	Cell shape determining protein MreB Mrl
GE376_RS22570	COG0285	dihydrofolate synthase activity
GE376_RS22585	COG1388	LysM domain
GE376_RS22595	COG0113	porphobilinogen synthase activity
GE376_RS22600	COG1587	Uroporphyrinogen-III synthase
GE376_RS22610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GE376_RS22620	COG1846	Transcriptional regulator
GE376_RS22625	COG1764	response to oxidative stress
GE376_RS22640	COG0470	DNA polymerase III
GE376_RS22640	COG1067	ATP-dependent peptidase activity
GE376_RS22685	COG0622	Phosphoesterase
GE376_RS22700	COG5401	PFAM Sporulation and spore germination
GE376_RS22720	COG1309	transcriptional regulator
GE376_RS22730	COG2197	response regulator
GE376_RS22735	COG2233	PERMEase
GE376_RS22740	COG0402	S-adenosylhomocysteine deaminase activity
GE376_RS22745	COG1983	PspC domain protein
GE376_RS22750	COG1396	sequence-specific DNA binding
GE376_RS22755	COG0697	spore germination
GE376_RS22765	COG1959	2 iron, 2 sulfur cluster binding
GE376_RS22770	COG1668	transmembrane transport
GE376_RS22775	COG4152	abc transporter atp-binding protein
GE376_RS22780	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GE376_RS22785	COG1360	Flagellar Motor Protein
GE376_RS22790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GE376_RS22795	COG1876	peptidase activity
GE376_RS22800	COG0824	Thioesterase
GE376_RS22805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GE376_RS22810	COG1053	succinate dehydrogenase
GE376_RS22815	COG2009	succinate dehydrogenase
GE376_RS22820	COG1719	4-vinyl reductase, 4VR
GE376_RS22830	COG3118	belongs to the thioredoxin family
GE376_RS22835	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GE376_RS22840	COG2086	electron transfer activity
GE376_RS22845	COG1024	Enoyl-CoA hydratase
GE376_RS22850	COG1309	transcriptional regulator
GE376_RS22855	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS22880	COG2318	DinB family
GE376_RS22905	COG1131	(ABC) transporter
GE376_RS22910	COG2205	protein histidine kinase activity
GE376_RS22915	COG0745	RESPONSE REGULATOR receiver
GE376_RS22920	COG4895	conserved protein (DUF2196)
GE376_RS22925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GE376_RS22935	COG4509	Sortase family
GE376_RS22940	COG1120	ATPase activity
GE376_RS22955	COG5386	Cell surface protein
GE376_RS22965	COG5386	Cell surface protein
GE376_RS22970	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS22975	COG1187	pseudouridine synthase activity
GE376_RS22985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GE376_RS22985	COG1796	DNA polymerase
GE376_RS22990	COG1286	toxin biosynthetic process
GE376_RS23030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GE376_RS23035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GE376_RS23045	COG1418	mRNA catabolic process
GE376_RS23065	COG2814	Major facilitator Superfamily
GE376_RS23070	COG1566	PFAM secretion protein HlyD family protein
GE376_RS23075	COG1309	transcriptional regulator
GE376_RS23080	COG1363	Peptidase, m42
GE376_RS23105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GE376_RS23120	COG1484	DNA-dependent DNA replication
GE376_RS23125	COG3611	Membrane attachment protein
GE376_RS23135	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GE376_RS23140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE376_RS23145	COG0237	dephospho-CoA kinase activity
GE376_RS23150	COG1971	Probably functions as a manganese efflux pump
GE376_RS23160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE376_RS23160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GE376_RS23165	COG5002	protein histidine kinase activity
GE376_RS23170	COG0745	RESPONSE REGULATOR receiver
GE376_RS23190	COG0538	isocitrate dehydrogenase activity
GE376_RS23195	COG0372	Belongs to the citrate synthase family
GE376_RS23205	COG0628	permease
GE376_RS23210	COG3030	protein affecting phage T7 exclusion by the F plasmid
GE376_RS23235	COG1725	Transcriptional regulator
GE376_RS23240	COG0281	malic enzyme
GE376_RS23245	COG0587	DNA-directed DNA polymerase activity
GE376_RS23260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GE376_RS23275	COG4109	DRTGG domain
GE376_RS23285	COG0006	proline dipeptidase activity
GE376_RS23325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS23330	COG0662	Cupin 2, conserved barrel domain protein
GE376_RS23345	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS23350	COG0589	response to stress
GE376_RS23385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS23410	COG0827	DNA restriction-modification system
GE376_RS23415	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GE376_RS23420	COG3874	Sporulation protein YtfJ
GE376_RS23435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GE376_RS23445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE376_RS23460	COG1104	cysteine desulfurase activity
GE376_RS23470	COG0583	DNA-binding transcription factor activity
GE376_RS23475	COG0697	spore germination
GE376_RS23480	COG1309	transcriptional regulator
GE376_RS23485	COG1956	GAF domain-containing protein
GE376_RS23490	COG0626	cystathionine gamma-synthase activity
GE376_RS23520	COG1595	DNA-templated transcription, initiation
GE376_RS23530	COG0110	maltose O-acetyltransferase activity
GE376_RS23535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GE376_RS23540	COG0454	-acetyltransferase
GE376_RS23545	COG0517	IMP dehydrogenase activity
GE376_RS23550	COG0123	including yeast histone deacetylase and acetoin utilization protein
GE376_RS23555	COG2267	carboxylic ester hydrolase activity
GE376_RS23565	COG0745	RESPONSE REGULATOR receiver
GE376_RS23570	COG5002	protein histidine kinase activity
GE376_RS23575	COG0666	response to abiotic stimulus
GE376_RS23605	COG1609	Transcriptional regulator
GE376_RS23615	COG4851	CamS sex pheromone cAM373 precursor
GE376_RS23620	COG3118	belongs to the thioredoxin family
GE376_RS23630	COG2309	aminopeptidase activity
GE376_RS23645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS23650	COG0697	spore germination
GE376_RS23655	COG0789	Transcriptional regulator
GE376_RS23670	COG1674	ftsk spoiiie
GE376_RS23675	COG0860	N-Acetylmuramoyl-L-alanine amidase
GE376_RS23685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GE376_RS23695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS23700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GE376_RS23705	COG1363	Peptidase, m42
GE376_RS23715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS23730	COG0510	thiamine kinase activity
GE376_RS23735	COG1523	belongs to the glycosyl hydrolase 13 family
GE376_RS23745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GE376_RS23750	COG1349	DNA-binding transcription factor activity
GE376_RS23755	COG1187	pseudouridine synthase activity
GE376_RS23760	COG2244	polysaccharide biosynthetic process
GE376_RS23765	COG2081	HI0933 family
GE376_RS23770	COG2814	Major facilitator Superfamily
GE376_RS23780	COG3832	glyoxalase III activity
GE376_RS23800	COG1329	Transcriptional regulator
GE376_RS23825	COG0314	molybdopterin synthase activity
GE376_RS23830	COG1763	Mo-molybdopterin cofactor biosynthetic process
GE376_RS23835	COG0303	'Molybdopterin
GE376_RS23845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GE376_RS23850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GE376_RS23870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GE376_RS23880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GE376_RS23920	COG2814	Major facilitator Superfamily
GE376_RS23925	COG0475	glutathione-regulated potassium exporter activity
GE376_RS23930	COG0490	domain, Protein
GE376_RS23935	COG0582	viral genome integration into host DNA
GE376_RS23945	COG1136	(ABC) transporter
GE376_RS23975	COG1242	4 iron, 4 sulfur cluster binding
GE376_RS23980	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GE376_RS23985	COG1131	(ABC) transporter
GE376_RS23995	COG1794	racemase activity, acting on amino acids and derivatives
GE376_RS24015	COG2267	carboxylic ester hydrolase activity
GE376_RS24020	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GE376_RS24025	COG0671	phosphoesterase, PA-phosphatase related
GE376_RS24030	COG0438	transferase activity, transferring glycosyl groups
GE376_RS24115	COG5002	protein histidine kinase activity
GE376_RS24120	COG3852	Histidine kinase
GE376_RS24125	COG0753	catalase activity
GE376_RS24130	COG2267	carboxylic ester hydrolase activity
GE376_RS24135	COG1368	sulfuric ester hydrolase activity
GE376_RS24160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GE376_RS24165	COG1116	anion transmembrane transporter activity
GE376_RS24170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GE376_RS24195	COG0494	nUDIX hydrolase
GE376_RS24225	COG1854	S-ribosylhomocysteine lyase activity
GE376_RS24235	COG0288	reversible hydration of carbon dioxide
GE376_RS24240	COG1271	oxidase subunit
GE376_RS24245	COG1294	oxidase, subunit
GE376_RS24260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS24285	COG1842	Phage shock protein A
GE376_RS24310	COG3859	Proton-coupled thiamine transporter YuaJ
GE376_RS24315	COG5002	protein histidine kinase activity
GE376_RS24320	COG0745	RESPONSE REGULATOR receiver
GE376_RS24345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GE376_RS24350	COG1597	lipid kinase activity
GE376_RS24360	COG0577	efflux transmembrane transporter activity
GE376_RS24365	COG1136	(ABC) transporter
GE376_RS24380	COG0586	Pfam SNARE associated Golgi protein
GE376_RS24390	COG0577	efflux transmembrane transporter activity
GE376_RS24395	COG1136	(ABC) transporter
GE376_RS24400	COG2207	Transcriptional regulator
GE376_RS24400	COG3708	Transcriptional regulator
GE376_RS24415	COG0640	Transcriptional regulator
GE376_RS24420	COG0745	RESPONSE REGULATOR receiver
GE376_RS24425	COG2205	protein histidine kinase activity
GE376_RS24430	COG0577	efflux transmembrane transporter activity
GE376_RS24435	COG0577	efflux transmembrane transporter activity
GE376_RS24440	COG1136	(ABC) transporter
GE376_RS24445	COG0577	efflux transmembrane transporter activity
GE376_RS24470	COG2188	Transcriptional regulator
GE376_RS24490	COG3964	amidohydrolase
GE376_RS24510	COG4948	Mandelate Racemase Muconate Lactonizing
GE376_RS24520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GE376_RS24525	COG0596	Alpha beta hydrolase
GE376_RS24535	COG1169	isochorismate synthase
GE376_RS24540	COG1575	Belongs to the MenA family. Type 1 subfamily
GE376_RS24545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GE376_RS24550	COG1278	Cold shock
GE376_RS24570	COG0058	SHG alpha-glucan phosphorylase activity
GE376_RS24580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GE376_RS24600	COG1404	Belongs to the peptidase S8 family
GE376_RS24735	COG1285	pathogenesis
GE376_RS24740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GE376_RS24755	COG2155	Conserved Protein
GE376_RS24760	COG1098	S1 RNA binding domain
GE376_RS24765	COG0436	Aminotransferase
GE376_RS24770	COG1522	sequence-specific DNA binding
GE376_RS24775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GE376_RS24780	COG2267	carboxylic ester hydrolase activity
GE376_RS24790	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GE376_RS24805	COG5018	Exonuclease
GE376_RS24810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE376_RS24830	COG2050	protein possibly involved in aromatic compounds catabolism
GE376_RS24840	COG1268	BioY protein
GE376_RS24845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE376_RS24850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GE376_RS24870	COG2076	Multidrug Resistance protein
GE376_RS24875	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GE376_RS24885	COG3584	3D domain protein
GE376_RS24900	COG1252	NADH dehydrogenase
GE376_RS24915	COG3708	Transcriptional regulator
GE376_RS24930	COG1683	Conserved Protein
GE376_RS24940	COG4122	O-methyltransferase activity
GE376_RS24960	COG0316	Belongs to the HesB IscA family
GE376_RS24975	COG1252	NADH dehydrogenase
GE376_RS24985	COG2274	protein secretion by the type I secretion system
GE376_RS24990	COG0390	transport system, permease component
GE376_RS24995	COG2824	Alkylphosphonate utilization operon protein PhnA
GE376_RS25015	COG4837	Protein of unknown function (DUF1462)
GE376_RS25020	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GE376_RS25030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GE376_RS25035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GE376_RS25055	COG1358	cellular component organization or biogenesis
GE376_RS25065	COG2249	NAD(P)H dehydrogenase (quinone) activity
GE376_RS25070	COG0647	UMP catabolic process
GE376_RS25080	COG2445	Protein of unknown function DUF86
GE376_RS25085	COG1494	fructose-1,6-bisphosphatase
GE376_RS25105	COG4470	Protein conserved in bacteria
GE376_RS25115	COG0789	Transcriptional regulator
GE376_RS25120	COG4377	Putative membrane peptidase family (DUF2324)
GE376_RS25150	COG0739	heme binding
GE376_RS25160	COG3377	Domain of unknown function (DUF1805)
GE376_RS25165	COG0737	Belongs to the 5'-nucleotidase family
GE376_RS25170	COG0719	Fe-S assembly protein
GE376_RS25175	COG0822	iron-sulfur transferase activity
GE376_RS25180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GE376_RS25185	COG0719	Fe-S assembly protein
GE376_RS25190	COG0396	ATPase activity
GE376_RS25195	COG1464	Belongs to the NlpA lipoprotein family
GE376_RS25200	COG1464	Belongs to the NlpA lipoprotein family
GE376_RS25205	COG2011	ABC-type metal ion transport system permease component
GE376_RS25220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS25225	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GE376_RS25235	COG1393	Belongs to the ArsC family
GE376_RS25270	COG0039	L-malate dehydrogenase activity
GE376_RS25290	COG1309	transcriptional regulator
GE376_RS25295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GE376_RS25300	COG1960	acyl-CoA dehydrogenase activity
GE376_RS25305	COG0183	Belongs to the thiolase family
GE376_RS25310	COG1024	Enoyl-CoA hydratase
GE376_RS25310	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE376_RS25320	COG1686	Belongs to the peptidase S11 family
GE376_RS25335	COG0011	TIGRFAM Protein of
GE376_RS25340	COG0840	transmembrane signaling receptor activity
GE376_RS25355	COG2814	Major facilitator Superfamily
GE376_RS25360	COG0531	amino acid
GE376_RS25385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS25420	COG0586	Pfam SNARE associated Golgi protein
GE376_RS25430	COG1376	ErfK ybiS ycfS ynhG family protein
GE376_RS25435	COG0745	RESPONSE REGULATOR receiver
GE376_RS25440	COG5002	protein histidine kinase activity
GE376_RS25470	COG0840	transmembrane signaling receptor activity
GE376_RS25475	COG2151	metal-sulfur cluster biosynthetic enzyme
GE376_RS25480	COG3227	Zinc metalloprotease (Elastase)
GE376_RS25500	COG0586	Pfam SNARE associated Golgi protein
GE376_RS25505	COG0475	glutathione-regulated potassium exporter activity
GE376_RS25510	COG0490	domain, Protein
GE376_RS25515	COG1115	amino acid carrier protein
GE376_RS25520	COG0783	Belongs to the Dps family
GE376_RS25530	COG2318	DinB family
GE376_RS25540	COG1611	Belongs to the LOG family
GE376_RS25550	COG1528	Iron-storage protein
GE376_RS25555	COG2311	Membrane
GE376_RS25560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS25565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS25570	COG1115	amino acid carrier protein
GE376_RS25575	COG1115	amino acid carrier protein
GE376_RS25580	COG2910	NAD(P)H-binding
GE376_RS25595	COG0656	L-ascorbic acid biosynthetic process
GE376_RS25600	COG2814	Major facilitator Superfamily
GE376_RS25605	COG1733	regulation of RNA biosynthetic process
GE376_RS25615	COG1252	NADH dehydrogenase
GE376_RS25620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GE376_RS25665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GE376_RS25680	COG1335	isochorismatase
GE376_RS25685	COG1522	sequence-specific DNA binding
GE376_RS25750	COG0557	exoribonuclease II activity
GE376_RS25755	COG1647	Serine aminopeptidase, S33
GE376_RS25760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GE376_RS25765	COG1346	cytolysis
GE376_RS25800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GE376_RS25815	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GE376_RS25825	COG1668	transmembrane transport
GE376_RS25830	COG4152	abc transporter atp-binding protein
GE376_RS25835	COG4585	Histidine kinase
GE376_RS25865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GE376_RS25880	COG2323	membrane
GE376_RS25890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS25900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GE376_RS25910	COG1051	belongs to the nudix hydrolase family
GE376_RS25920	COG0492	ferredoxin-NADP+ reductase activity
GE376_RS25925	COG0457	Tetratricopeptide repeat
GE376_RS25930	COG0110	maltose O-acetyltransferase activity
GE376_RS25950	COG1950	PFAM Membrane protein of
GE376_RS25955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GE376_RS25975	COG0789	Transcriptional regulator
GE376_RS25995	COG0583	DNA-binding transcription factor activity
GE376_RS26005	COG0655	NAD(P)H dehydrogenase (quinone) activity
GE376_RS26020	COG1132	(ABC) transporter
GE376_RS26025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_RS26030	COG0793	Belongs to the peptidase S41A family
GE376_RS26030	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS26035	COG2177	Part of the ABC transporter FtsEX involved in
GE376_RS26040	COG2884	Cell division ATP-binding protein ftsE
GE376_RS26060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GE376_RS26065	COG1278	Cold shock
GE376_RS26075	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GE376_RS26080	COG0791	NLP P60 protein
GE376_RS26080	COG1388	LysM domain
GE376_RS26085	COG1733	regulation of RNA biosynthetic process
GE376_RS26090	COG1307	EDD domain protein, DegV family
GE376_RS26095	COG1739	Uncharacterized protein family UPF0029
GE376_RS26100	COG1316	TRANSCRIPTIONal
GE376_RS26105	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GE376_RS26110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GE376_RS26115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GE376_RS26125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GE376_RS26125	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GE376_RS26145	COG1486	melibiose metabolic process
GE376_RS26150	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE376_RS26155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE376_RS26175	COG1447	Phosphotransferase system cellobiose-specific component IIA
GE376_RS26185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GE376_RS26190	COG1301	dicarboxylic acid transport
GE376_RS26205	COG1511	domain protein
GE376_RS26210	COG0583	DNA-binding transcription factor activity
GE376_RS26215	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GE376_RS26220	COG1271	oxidase subunit
GE376_RS26225	COG1294	oxidase, subunit
GE376_RS26230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GE376_RS26260	COG1620	l-lactate permease
GE376_RS26270	COG2389	metal-binding protein
GE376_RS26280	COG1368	sulfuric ester hydrolase activity
GE376_RS26290	COG1388	LysM domain
GE376_RS26290	COG0791	NLP P60 protein
GE376_RS26295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GE376_RS26305	COG1215	transferase activity, transferring glycosyl groups
GE376_RS26310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GE376_RS26315	COG1388	LysM domain
GE376_RS26315	COG3584	3D domain protein
GE376_RS26340	COG4715	Zinc finger, swim domain protein
GE376_RS26345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GE376_RS26385	COG0577	efflux transmembrane transporter activity
GE376_RS26390	COG1136	(ABC) transporter
GE376_RS26425	COG5002	protein histidine kinase activity
GE376_RS26430	COG0745	RESPONSE REGULATOR receiver
GE376_RS26435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE376_RS26455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GE376_RS26460	COG2244	polysaccharide biosynthetic process
GE376_RS26480	COG0438	transferase activity, transferring glycosyl groups
GE376_RS26485	COG0438	transferase activity, transferring glycosyl groups
GE376_RS26500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GE376_RS26505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GE376_RS26510	COG1086	Polysaccharide biosynthesis protein
GE376_RS26515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GE376_RS26520	COG4464	protein tyrosine phosphatase activity
GE376_RS26525	COG0489	protein tyrosine kinase activity
GE376_RS26530	COG3944	biosynthesis protein
GE376_RS26535	COG0489	protein tyrosine kinase activity
GE376_RS26550	COG1609	Transcriptional regulator
GE376_RS26560	COG0739	heme binding
GE376_RS26575	COG3279	Response regulator of the LytR AlgR family
GE376_RS26580	COG2385	sporulation resulting in formation of a cellular spore
GE376_RS26595	COG4836	Membrane
GE376_RS26600	COG1007	ATP synthesis coupled electron transport
GE376_RS26605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GE376_RS26610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GE376_RS26620	COG0839	Belongs to the complex I subunit 6 family
GE376_RS26640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GE376_RS26655	COG5001	Diguanylate cyclase
GE376_RS26655	COG3300	MHYT domain
GE376_RS26705	COG0356	it plays a direct role in the translocation of protons across the membrane
GE376_RS26740	COG0698	ribose 5-phosphate isomerase
GE376_RS26750	COG2190	(PTS) system
GE376_RS26755	COG2259	Doxx family
GE376_RS26760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GE376_RS26775	COG0009	L-threonylcarbamoyladenylate synthase
GE376_RS26810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GE376_RS26815	COG1494	fructose-1,6-bisphosphatase
GE376_RS26835	COG4821	SIS domain
GE376_RS26845	COG3343	RNA polymerase activity
GE376_RS26855	COG1960	acyl-CoA dehydrogenase activity
GE376_RS26860	COG1960	acyl-CoA dehydrogenase activity
GE376_RS26865	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE376_RS26875	COG2181	nitrate reductase activity
GE376_RS26875	COG0247	lactate metabolic process
GE376_RS26880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GE376_RS26890	COG3300	MHYT domain
GE376_RS26890	COG5001	Diguanylate cyclase
GE376_RS26905	COG3227	Zinc metalloprotease (Elastase)
GE376_RS26910	COG2197	response regulator
GE376_RS26915	COG4585	Histidine kinase
GE376_RS26920	COG0842	Transport permease protein
GE376_RS26925	COG1131	(ABC) transporter
GE376_RS26930	COG0024	Methionine aminopeptidase
GE376_RS26940	COG2234	aminopeptidase activity
GE376_RS26960	COG1595	DNA-templated transcription, initiation
GE376_RS26970	COG4506	Protein conserved in bacteria
GE376_RS26975	COG1619	proteins homologs of microcin C7 resistance protein MccF
GE376_RS27000	COG2814	Major facilitator Superfamily
GE376_RS27005	COG0789	Transcriptional regulator
GE376_RS27010	COG0584	glycerophosphoryl diester phosphodiesterase
GE376_RS27015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_RS27025	COG1994	Peptidase M50
GE376_RS27035	COG1078	dGTPase activity
GE376_RS27040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GE376_RS27045	COG1120	ATPase activity
GE376_RS27050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS27055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GE376_RS27075	COG0280	phosphate acetyltransferase
GE376_RS27090	COG3773	Cell wall hydrolase
GE376_RS27100	COG2363	Small membrane protein
GE376_RS27110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GE376_RS27115	COG2233	PERMEase
GE376_RS27120	COG0561	phosphatase activity
GE376_RS27125	COG2814	Major facilitator Superfamily
GE376_RS27135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GE376_RS27140	COG1131	(ABC) transporter
GE376_RS27145	COG2755	lipolytic protein G-D-S-L family
GE376_RS27150	COG1609	Transcriptional regulator
GE376_RS27160	COG0460	homoserine dehydrogenase
GE376_RS27170	COG2873	o-acetylhomoserine
GE376_RS27180	COG1011	Hydrolase
GE376_RS27185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_RS27195	COG2197	response regulator
GE376_RS27200	COG2203	Gaf domain
GE376_RS27200	COG4585	Histidine kinase
GE376_RS27205	COG0351	phosphomethylpyrimidine kinase
GE376_RS27210	COG3706	GGDEF domain
GE376_RS27215	COG2879	small protein
GE376_RS27220	COG1966	Carbon starvation protein
GE376_RS27225	COG3279	Response regulator of the LytR AlgR family
GE376_RS27230	COG0477	Major facilitator Superfamily
GE376_RS27240	COG0438	transferase activity, transferring glycosyl groups
GE376_RS27255	COG0840	transmembrane signaling receptor activity
GE376_RS27265	COG1607	acyl-coa hydrolase
GE376_RS27270	COG1216	Glycosyl transferase, family 2
GE376_RS27280	COG1216	Glycosyl transferase, family 2
GE376_RS27300	COG0488	(ABC) transporter
GE376_RS27305	COG1696	Membrane protein involved in D-alanine export
GE376_RS27315	COG1309	transcriptional regulator
GE376_RS27320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GE376_RS27325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE376_RS27325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GE376_RS27330	COG0628	permease
GE376_RS27350	COG3275	phosphorelay sensor kinase activity
GE376_RS27355	COG2814	Major facilitator Superfamily
GE376_RS27360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GE376_RS27365	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GE376_RS27390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GE376_RS27395	COG1272	protein, Hemolysin III
GE376_RS27415	COG1164	Oligoendopeptidase f
GE376_RS27425	COG5002	protein histidine kinase activity
GE376_RS27440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_RS27445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GE376_RS27450	COG4853	Protein conserved in bacteria
GE376_RS27460	COG5002	protein histidine kinase activity
GE376_RS27465	COG0745	RESPONSE REGULATOR receiver
GE376_RS27495	COG0305	Participates in initiation and elongation during chromosome replication
GE376_RS27505	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GE376_RS27510	COG4241	membrane
GE376_RS27520	COG0629	single-stranded DNA binding
GE376_RS27530	COG0012	GTP binding
GE376_RS27535	COG4481	Protein conserved in bacteria
GE376_RS27540	COG0668	transmembrane transport
GE376_RS27550	COG1475	DNA binding
GE376_RS27555	COG1192	Involved in chromosome partitioning
GE376_RS27580	COG1847	R3H domain protein
GE376_RS27585	COG0706	membrane insertase activity
GE376_RS27595	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GE376_RS27640	COG1396	sequence-specific DNA binding
GE376_RS27660	COG1309	transcriptional regulator
GE376_RS27665	COG0367	asparagine synthase
GE376_RS27730	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS27730	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS27735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GE376_RS27775	COG1136	(ABC) transporter
GE376_RS27835	COG0457	Tetratricopeptide repeat
GE376_RS27860	COG0457	Tetratricopeptide repeat
GE376_RS27970	COG1201	RNA secondary structure unwinding
GE376_RS27995	COG1396	sequence-specific DNA binding
GE376_RS28045	COG3800	Transcriptional regulator
GE376_RS28045	COG1396	sequence-specific DNA binding
GE376_RS28110	COG1024	Enoyl-CoA hydratase
GE376_RS28115	COG1216	Glycosyl transferase, family 2
GE376_RS28115	COG0463	Glycosyl transferase, family 2
GE376_RS28130	COG1396	sequence-specific DNA binding
GE376_RS28155	COG0667	Aldo Keto reductase
GE376_RS28175	COG0542	response to heat
GE376_RS28180	COG0300	oxidoreductase activity
GE376_RS28180	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS28180	COG3321	synthase
GE376_RS28180	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS28180	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS28180	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS28180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_RS28180	COG3321	synthase
GE376_RS28180	COG0300	oxidoreductase activity
GE376_RS28180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_RS28200	COG1960	acyl-CoA dehydrogenase activity
GE376_RS28215	COG1250	3-hydroxyacyl-CoA dehydrogenase
GE376_RS28220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GE376_RS28235	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS28235	COG3321	synthase
GE376_RS28235	COG0318	PFAM AMP-dependent synthetase and ligase
GE376_RS28235	COG0300	oxidoreductase activity
GE376_RS28235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GE376_RS28240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GE376_RS28275	COG1609	Transcriptional regulator
GE376_RS28280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GE376_RS28285	COG0561	phosphatase activity
GE376_RS28290	COG0673	inositol 2-dehydrogenase activity
GE376_RS28295	COG0738	Major facilitator superfamily
GE376_RS28315	COG1475	DNA binding
GE376_RS28405	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GE376_RS28410	COG1131	(ABC) transporter
GE376_RS28435	COG0574	Belongs to the PEP-utilizing enzyme family
GE376_RS28435	COG3848	Pyruvate phosphate dikinase
GE376_RS28440	COG0574	Belongs to the PEP-utilizing enzyme family
GE376_RS28440	COG3848	Pyruvate phosphate dikinase
GE376_RS28475	COG3480	Lon protease (S16) C-terminal proteolytic domain
GE376_RS28565	COG3344	reverse transcriptase
GE376_RS28585	COG0494	nUDIX hydrolase
GE376_RS28635	COG0463	Glycosyl transferase, family 2
GE376_RS28640	COG0463	Glycosyl transferase, family 2
GE376_RS28645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GE376_RS28655	COG1088	dTDP-glucose 4,6-dehydratase activity
GE376_RS28660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GE376_RS28665	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GE376_RS28680	COG2089	acid synthase
GE376_RS28685	COG4641	Protein conserved in bacteria
GE376_RS28705	COG1309	transcriptional regulator
GE376_RS28710	COG2814	Major facilitator Superfamily
GE376_RS28720	COG0657	acetylesterase activity
GE376_RS28730	COG5002	protein histidine kinase activity
GE376_RS28765	COG4974	Belongs to the 'phage' integrase family
GE376_RS28785	COG5634	Uncharacterized conserved protein (DUF2278)
GE376_RS28805	COG1876	peptidase activity
GE376_RS28815	COG2239	Acts as a magnesium transporter
GE376_RS28830	COG0772	Belongs to the SEDS family
GE376_RS28835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GE376_RS28850	COG1802	Transcriptional regulator
GE376_RS28855	COG0697	spore germination
GE376_RS28875	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GE376_RS28885	COG0076	glutamate decarboxylase activity
GE376_RS28930	COG3961	Belongs to the TPP enzyme family
GE376_RS28940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GE376_RS28940	COG0723	plastoquinol--plastocyanin reductase activity
GE376_RS28945	COG2124	cytochrome p450
GE376_RS28955	COG1923	regulation of RNA biosynthetic process
GE376_RS28970	COG0840	transmembrane signaling receptor activity
GE376_RS28975	COG2184	nucleotidyltransferase activity
GE376_RS28985	COG1522	sequence-specific DNA binding
GE376_RS28990	COG0531	amino acid
GE376_RS29010	COG1923	regulation of RNA biosynthetic process
GE376_RS29030	COG3591	Belongs to the peptidase S1B family
GE376_RS29070	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS29080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GE376_RS29090	COG3104	oligopeptide transport
GE376_RS29110	COG2423	ornithine cyclodeaminase activity
GE376_RS29125	COG2091	lysine biosynthetic process via aminoadipic acid
GE376_RS29155	COG2366	antibiotic biosynthetic process
GE376_RS29160	COG2211	Major facilitator Superfamily
GE376_RS29170	COG0697	spore germination
GE376_RS29175	COG1802	Transcriptional regulator
GE376_RS29180	COG0697	spore germination
GE376_RS29210	COG2002	toxin-antitoxin pair type II binding
GE376_RS29215	COG0776	regulation of translation
GE376_RS29225	COG0776	regulation of translation
GE376_RS29230	COG5504	Zn-dependent protease
GE376_RS29235	COG0789	Transcriptional regulator
GE376_RS29285	COG2329	Antibiotic biosynthesis monooxygenase
GE376_RS29315	COG2311	Membrane
GE376_RS29345	COG1329	Transcriptional regulator
GE376_RS29365	COG1278	Cold shock
GE376_RS29380	COG1131	(ABC) transporter
GE376_RS29385	COG1725	Transcriptional regulator
GE376_RS29485	COG3331	DNA recombination
GE376_RS29515	COG0322	excinuclease ABC activity
GE376_RS29745	COG3693	PFAM glycoside hydrolase, family 10
GE376_RS29760	COG2020	methyltransferase activity
GE376_RS29775	COG2318	DinB family
GE376_RS29870	COG0457	Tetratricopeptide repeat
GE376_RS29880	COG3583	domain protein
GE376_RS29880	COG3584	3D domain protein
GE376_RS29885	COG0791	NLP P60 protein
GE376_RS29885	COG1388	LysM domain
GE376_RS29890	COG0739	heme binding
GE376_RS29890	COG0741	lytic transglycosylase activity
GE376_RS29890	COG1196	nuclear chromosome segregation
GE376_RS29930	COG2234	aminopeptidase activity
GE376_RS29935	COG5634	Uncharacterized conserved protein (DUF2278)
GE376_RS29970	COG0739	heme binding
GE376_RS29975	COG1388	LysM domain
GE376_RS29975	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS29975	COG3409	Peptidoglycan-binding domain 1 protein
GE376_RS29990	COG5632	N-Acetylmuramoyl-L-alanine amidase
GE376_RS30020	COG0745	RESPONSE REGULATOR receiver
GE376_RS30025	COG2205	protein histidine kinase activity
GE376_RS30030	COG1136	(ABC) transporter
GE376_RS30035	COG0577	efflux transmembrane transporter activity
GE376_RS30060	COG0768	penicillin binding
GE376_RS30070	COG0741	lytic transglycosylase activity
GE376_RS30075	COG0772	Belongs to the SEDS family
GE376_RS30170	COG0697	spore germination
GE376_RS30180	COG1114	Component of the transport system for branched-chain amino acids
GE376_RS30185	COG1115	amino acid carrier protein
GE376_RS30215	COG3754	Rhamnan synthesis protein F
GE376_RS30220	COG1131	(ABC) transporter
GE376_RS30225	COG0842	Transport permease protein
GE376_RS30240	COG1028	Short-chain dehydrogenase reductase Sdr
GE376_RS30250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GE376_RS30265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GE376_RS30270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GE376_RS30290	COG1091	dTDP-4-dehydrorhamnose reductase activity
GE376_RS30330	COG2040	homocysteine
GE376_RS30335	COG0833	amino acid
GE376_RS30340	COG1482	cell wall glycoprotein biosynthetic process
GE376_RS30345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_RS30345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS30345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GE376_RS30350	COG3711	transcriptional antiterminator
GE376_RS30350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS30385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GE376_RS30390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS30395	COG3271	cysteine-type peptidase activity
GE376_RS30395	COG2274	protein secretion by the type I secretion system
GE376_RS30405	COG3344	reverse transcriptase
GE376_RS30430	COG0697	spore germination
GE376_RS30475	COG2197	response regulator
GE376_RS30490	COG4499	WXG100 protein secretion system (Wss), protein YukC
GE376_RS30490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GE376_RS30540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GE376_RS30570	COG3011	Protein conserved in bacteria
GE376_RS30585	COG1136	(ABC) transporter
GE376_RS30635	COG1132	(ABC) transporter
GE376_RS30645	COG1309	transcriptional regulator
GE376_RS30650	COG2357	RelA SpoT domain protein
GE376_RS30665	COG2814	Major facilitator Superfamily
GE376_RS30690	COG0640	Transcriptional regulator
GE376_RS30695	COG2814	Major facilitator Superfamily
GE376_RS30700	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GE376_RS30730	COG1408	metallophosphoesterase
GE376_RS30765	COG2732	(Barnase) inhibitor
GE376_RS30785	COG2002	toxin-antitoxin pair type II binding
GE376_RS30820	COG1012	belongs to the aldehyde dehydrogenase family
GE376_RS30820	COG1454	alcohol dehydrogenase
GE376_RS30830	COG0535	radical SAM domain protein
GE376_RS30840	COG1328	CTP reductase activity
GE376_RS30840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GE376_RS30855	COG0426	domain, Protein
GE376_RS30860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_RS30865	COG1773	rubredoxin
GE376_RS30870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GE376_RS30885	COG4990	cell redox homeostasis
GE376_RS30890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GE376_RS30895	COG2116	formate transmembrane transporter activity
GE376_RS30910	COG0531	amino acid
GE376_RS30925	COG0531	amino acid
GE376_RS30930	COG0657	acetylesterase activity
GE376_RS30960	COG2070	2-Nitropropane dioxygenase
GE376_RS30970	COG5002	protein histidine kinase activity
GE376_RS30975	COG0745	RESPONSE REGULATOR receiver
GE376_RS30980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GE376_RS30985	COG0577	efflux transmembrane transporter activity
GE376_RS30990	COG1136	(ABC) transporter
GE376_RS31015	COG0823	Involved in the tonB-independent uptake of proteins
GE376_RS31030	COG1131	(ABC) transporter
GE376_RS31045	COG3979	chitinase
GE376_RS31055	COG3604	Transcriptional regulator
GE376_RS31060	COG2376	Dihydroxyacetone kinase
GE376_RS31070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GE376_RS31075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GE376_RS31085	COG3715	PTS system
GE376_RS31090	COG3716	PTS system mannose fructose sorbose family IID component
GE376_RS31110	COG1846	Transcriptional regulator
GE376_RS31130	COG2002	toxin-antitoxin pair type II binding
GE376_RS31140	COG1923	regulation of RNA biosynthetic process
GE376_RS31160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GE376_RS31160	COG0456	acetyltransferase
GE376_RS31180	COG0583	DNA-binding transcription factor activity
GE376_RS31185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GE376_RS31210	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GE376_RS31215	COG0463	Glycosyl transferase, family 2
GE376_RS31220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GE376_RS31225	COG3271	cysteine-type peptidase activity
GE376_RS31225	COG2274	protein secretion by the type I secretion system
GE376_RS31240	COG0582	viral genome integration into host DNA