locus-tag	class	description
FI644_RS00010	COG1757	Na H antiporter
FI644_RS00015	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FI644_RS00025	COG3339	Conserved Protein
FI644_RS00030	COG3773	Cell wall hydrolase
FI644_RS00035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI644_RS00045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI644_RS00050	COG1116	anion transmembrane transporter activity
FI644_RS00055	COG0084	hydrolase, TatD family'
FI644_RS00070	COG2268	Band 7 protein
FI644_RS00075	COG1585	Membrane protein implicated in regulation of membrane protease activity
FI644_RS00080	COG2151	metal-sulfur cluster biosynthetic enzyme
FI644_RS00100	COG1473	amidohydrolase
FI644_RS00110	COG2195	Cleaves the N-terminal amino acid of tripeptides
FI644_RS00115	COG1252	NADH dehydrogenase
FI644_RS00125	COG1612	heme a metabolic process
FI644_RS00130	COG2226	methyltransferase
FI644_RS00135	COG2270	Major facilitator Superfamily
FI644_RS00145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FI644_RS00165	COG4152	abc transporter atp-binding protein
FI644_RS00170	COG1960	acyl-CoA dehydrogenase activity
FI644_RS00175	COG0516	GMP reductase activity
FI644_RS00175	COG0517	IMP dehydrogenase activity
FI644_RS00190	COG1126	abc transporter atp-binding protein
FI644_RS00195	COG0765	amino acid transport
FI644_RS00200	COG0765	amino acid transport
FI644_RS00205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI644_RS00210	COG5001	Diguanylate cyclase
FI644_RS00225	COG0730	response to heat
FI644_RS00230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI644_RS00230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FI644_RS00235	COG0425	Belongs to the sulfur carrier protein TusA family
FI644_RS00235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FI644_RS00240	COG2210	Belongs to the sulfur carrier protein TusA family
FI644_RS00245	COG0425	Belongs to the sulfur carrier protein TusA family
FI644_RS00255	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI644_RS00265	COG1054	Belongs to the UPF0176 family
FI644_RS00270	COG1937	Protein conserved in bacteria
FI644_RS00275	COG0753	catalase activity
FI644_RS00285	COG0456	acetyltransferase
FI644_RS00300	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FI644_RS00310	COG1396	sequence-specific DNA binding
FI644_RS00310	COG3800	Transcriptional regulator
FI644_RS00330	COG2358	TRAP transporter, solute receptor (TAXI family
FI644_RS00335	COG2382	esterase
FI644_RS00340	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FI644_RS00345	COG2153	protein acetylation
FI644_RS00355	COG0210	DNA helicase
FI644_RS00375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FI644_RS00405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FI644_RS00410	COG0475	glutathione-regulated potassium exporter activity
FI644_RS00410	COG0569	domain protein
FI644_RS00415	COG2239	Acts as a magnesium transporter
FI644_RS00420	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FI644_RS00425	COG0564	pseudouridine synthase activity
FI644_RS00435	COG2357	RelA SpoT domain protein
FI644_RS00445	COG4116	CYTH
FI644_RS00450	COG0741	lytic transglycosylase activity
FI644_RS00455	COG2346	COG2346, Truncated hemoglobins
FI644_RS00460	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FI644_RS00470	COG1164	Oligoendopeptidase f
FI644_RS00480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FI644_RS00485	COG4862	establishment of competence for transformation
FI644_RS00490	COG1393	Belongs to the ArsC family
FI644_RS00495	COG0456	acetyltransferase
FI644_RS00505	COG4608	Belongs to the ABC transporter superfamily
FI644_RS00510	COG0444	Belongs to the ABC transporter superfamily
FI644_RS00515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS00520	COG0601	transmembrane transport
FI644_RS00525	COG4166	transmembrane transport
FI644_RS00530	COG0180	Tryptophanyl-tRNA synthetase
FI644_RS00540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS00545	COG0601	transmembrane transport
FI644_RS00555	COG4608	Belongs to the ABC transporter superfamily
FI644_RS00560	COG0444	Belongs to the ABC transporter superfamily
FI644_RS00565	COG5504	Zn-dependent protease
FI644_RS00570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FI644_RS00575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FI644_RS00590	COG1744	ABC transporter substrate-binding protein PnrA-like
FI644_RS00600	COG2267	carboxylic ester hydrolase activity
FI644_RS00610	COG0542	response to heat
FI644_RS00625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FI644_RS00635	COG0505	Belongs to the CarA family
FI644_RS00645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FI644_RS00650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FI644_RS00660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI644_RS00670	COG1763	Mo-molybdopterin cofactor biosynthetic process
FI644_RS00675	COG0303	'Molybdopterin
FI644_RS00680	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FI644_RS00685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FI644_RS00690	COG0535	radical SAM domain protein
FI644_RS00695	COG0840	transmembrane signaling receptor activity
FI644_RS00705	COG2996	Protein conserved in bacteria
FI644_RS00715	COG1307	EDD domain protein, DegV family
FI644_RS00720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS00735	COG0561	phosphatase activity
FI644_RS00740	COG1073	alpha beta
FI644_RS00745	COG2151	metal-sulfur cluster biosynthetic enzyme
FI644_RS00755	COG1874	Beta-galactosidase
FI644_RS00755	COG0366	Alpha amylase catalytic
FI644_RS00765	COG3300	MHYT domain
FI644_RS00765	COG5001	Diguanylate cyclase
FI644_RS00775	COG0179	Fumarylacetoacetate (FAA) hydrolase
FI644_RS00780	COG2311	Membrane
FI644_RS00815	COG1074	ATP-dependent DNA helicase activity
FI644_RS00820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FI644_RS00830	COG0398	Pfam SNARE associated Golgi protein
FI644_RS00840	COG0823	Involved in the tonB-independent uptake of proteins
FI644_RS00840	COG1506	peptidase
FI644_RS00840	COG4946	Tricorn protease homolog
FI644_RS00850	COG4903	ComK protein
FI644_RS00860	COG0501	Belongs to the peptidase M48B family
FI644_RS00870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FI644_RS00875	COG1396	sequence-specific DNA binding
FI644_RS00885	COG4120	Belongs to the binding-protein-dependent transport system permease family
FI644_RS00895	COG1024	Enoyl-CoA hydratase
FI644_RS00900	COG0318	PFAM AMP-dependent synthetase and ligase
FI644_RS00910	COG1595	DNA-templated transcription, initiation
FI644_RS00915	COG0095	Lipoate-protein ligase
FI644_RS00920	COG1234	tRNA 3'-trailer cleavage
FI644_RS00935	COG1511	domain protein
FI644_RS00940	COG1309	transcriptional regulator
FI644_RS00945	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FI644_RS00950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FI644_RS00955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FI644_RS00960	COG2329	Antibiotic biosynthesis monooxygenase
FI644_RS00975	COG1473	amidohydrolase
FI644_RS00985	COG4473	ABC transporter
FI644_RS00990	COG1131	(ABC) transporter
FI644_RS00995	COG0537	adenosine 5'-monophosphoramidase activity
FI644_RS01000	COG1254	Belongs to the acylphosphatase family
FI644_RS01015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FI644_RS01035	COG1846	Transcriptional regulator
FI644_RS01065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FI644_RS01080	COG4717	serine-type aminopeptidase activity
FI644_RS01085	COG0420	3'-5' exonuclease activity
FI644_RS01090	COG1668	transmembrane transport
FI644_RS01095	COG4152	abc transporter atp-binding protein
FI644_RS01105	COG1024	Enoyl-CoA hydratase
FI644_RS01110	COG0318	PFAM AMP-dependent synthetase and ligase
FI644_RS01115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FI644_RS01120	COG0561	phosphatase activity
FI644_RS01125	COG0840	transmembrane signaling receptor activity
FI644_RS01130	COG1090	epimerase
FI644_RS01140	COG3679	Belongs to the UPF0342 family
FI644_RS01145	COG4399	Belongs to the UPF0754 family
FI644_RS01155	COG0189	ligase activity
FI644_RS01160	COG0189	ligase activity
FI644_RS01165	COG0189	ligase activity
FI644_RS01195	COG0393	Putative heavy-metal-binding
FI644_RS01215	COG1595	DNA-templated transcription, initiation
FI644_RS01240	COG3852	Histidine kinase
FI644_RS01245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS01250	COG1253	flavin adenine dinucleotide binding
FI644_RS01255	COG0789	Transcriptional regulator
FI644_RS01260	COG1253	flavin adenine dinucleotide binding
FI644_RS01265	COG3850	Histidine kinase
FI644_RS01265	COG5002	protein histidine kinase activity
FI644_RS01270	COG0745	RESPONSE REGULATOR receiver
FI644_RS01280	COG2252	PERMEase
FI644_RS01290	COG2201	protein-glutamate methylesterase activity
FI644_RS01295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS01305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS01310	COG4122	O-methyltransferase activity
FI644_RS01320	COG2514	catechol 2,3-dioxygenase activity
FI644_RS01325	COG1733	regulation of RNA biosynthetic process
FI644_RS01330	COG2719	SpoVR family
FI644_RS01335	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FI644_RS01340	COG3684	Belongs to the aldolase LacD family
FI644_RS01345	COG1105	Belongs to the carbohydrate kinase PfkB family
FI644_RS01355	COG2222	sugar isomerase
FI644_RS01360	COG1940	carbohydrate kinase activity
FI644_RS01365	COG0395	ABC-type sugar transport system, permease component
FI644_RS01370	COG1175	transmembrane transport
FI644_RS01390	COG2188	Transcriptional regulator
FI644_RS01395	COG5426	von Willebrand factor, type A
FI644_RS01400	COG0395	ABC-type sugar transport system, permease component
FI644_RS01405	COG1175	transmembrane transport
FI644_RS01415	COG2169	Transcriptional regulator
FI644_RS01420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FI644_RS01425	COG3842	ATPase activity
FI644_RS01430	COG2508	Transcriptional regulator
FI644_RS01445	COG3850	Histidine kinase
FI644_RS01445	COG5002	protein histidine kinase activity
FI644_RS01450	COG0745	RESPONSE REGULATOR receiver
FI644_RS01465	COG2197	response regulator
FI644_RS01470	COG4585	Histidine kinase
FI644_RS01470	COG2203	Gaf domain
FI644_RS01475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FI644_RS01495	COG0564	pseudouridine synthase activity
FI644_RS01500	COG2261	transglycosylase associated protein
FI644_RS01505	COG1858	cytochrome C peroxidase
FI644_RS01510	COG1392	Phosphate transport regulator
FI644_RS01515	COG0306	phosphate transporter
FI644_RS01520	COG2252	PERMEase
FI644_RS01525	COG3104	oligopeptide transport
FI644_RS01530	COG1823	symporter activity
FI644_RS01540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FI644_RS01555	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FI644_RS01560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FI644_RS01600	COG2718	Belongs to the UPF0229 family
FI644_RS01605	COG2766	serine protein kinase
FI644_RS01610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FI644_RS01620	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FI644_RS01625	COG3382	B3 4 domain protein
FI644_RS01635	COG1454	alcohol dehydrogenase
FI644_RS01640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FI644_RS01640	COG1263	PTS System
FI644_RS01655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS01660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS01665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS01670	COG1120	ATPase activity
FI644_RS01675	COG2819	hydrolase of the alpha beta superfamily
FI644_RS01680	COG0737	Belongs to the 5'-nucleotidase family
FI644_RS01690	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FI644_RS01695	COG3639	organic phosphonate transmembrane transporter activity
FI644_RS01705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS01710	COG0697	spore germination
FI644_RS01715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS01725	COG0668	transmembrane transport
FI644_RS01730	COG1309	transcriptional regulator
FI644_RS01735	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS01755	COG1819	glycosyl
FI644_RS01770	COG2205	protein histidine kinase activity
FI644_RS01775	COG0745	RESPONSE REGULATOR receiver
FI644_RS01785	COG0577	efflux transmembrane transporter activity
FI644_RS01790	COG1136	(ABC) transporter
FI644_RS01815	COG1309	transcriptional regulator
FI644_RS01830	COG0681	Belongs to the peptidase S26 family
FI644_RS01855	COG3320	Male sterility
FI644_RS01855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FI644_RS01860	COG1309	transcriptional regulator
FI644_RS01885	COG1793	dna ligase
FI644_RS01955	COG0861	Integral membrane protein TerC family
FI644_RS01965	COG1172	Belongs to the binding-protein-dependent transport system permease family
FI644_RS01970	COG1129	ABC transporter
FI644_RS01985	COG0673	inositol 2-dehydrogenase activity
FI644_RS02005	COG1609	Transcriptional regulator
FI644_RS02010	COG1082	Xylose isomerase domain protein TIM barrel
FI644_RS02040	COG0662	Cupin 2, conserved barrel domain protein
FI644_RS02045	COG5504	Zn-dependent protease
FI644_RS02060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FI644_RS02105	COG2003	Belongs to the UPF0758 family
FI644_RS02125	COG0515	serine threonine protein kinase
FI644_RS02125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FI644_RS02160	COG0586	Pfam SNARE associated Golgi protein
FI644_RS02210	COG2192	nodulation
FI644_RS02220	COG2192	nodulation
FI644_RS02225	COG1132	(ABC) transporter
FI644_RS02230	COG1132	(ABC) transporter
FI644_RS02255	COG0673	inositol 2-dehydrogenase activity
FI644_RS02275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FI644_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS02285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FI644_RS02325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FI644_RS02365	COG0386	Belongs to the glutathione peroxidase family
FI644_RS02380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FI644_RS02385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FI644_RS02410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FI644_RS02415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FI644_RS02420	COG5285	phytanoyl-CoA dioxygenase
FI644_RS02425	COG1082	Xylose isomerase domain protein TIM barrel
FI644_RS02440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FI644_RS02455	COG0318	PFAM AMP-dependent synthetase and ligase
FI644_RS02485	COG0736	holo-[acyl-carrier-protein] synthase activity
FI644_RS02515	COG0454	-acetyltransferase
FI644_RS02520	COG1595	DNA-templated transcription, initiation
FI644_RS02545	COG1309	transcriptional regulator
FI644_RS02560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FI644_RS02565	COG0583	DNA-binding transcription factor activity
FI644_RS02570	COG2226	methyltransferase
FI644_RS02575	COG1309	transcriptional regulator
FI644_RS02635	COG0456	acetyltransferase
FI644_RS02650	COG1794	racemase activity, acting on amino acids and derivatives
FI644_RS02675	COG2814	Major facilitator Superfamily
FI644_RS02690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FI644_RS02770	COG2003	Belongs to the UPF0758 family
FI644_RS02810	COG0656	L-ascorbic acid biosynthetic process
FI644_RS02815	COG0640	Transcriptional regulator
FI644_RS02825	COG0860	N-Acetylmuramoyl-L-alanine amidase
FI644_RS02830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FI644_RS02835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FI644_RS02915	COG2801	Transposase and inactivated derivatives
FI644_RS02920	COG2249	NAD(P)H dehydrogenase (quinone) activity
FI644_RS02925	COG1733	regulation of RNA biosynthetic process
FI644_RS02975	COG2217	Heavy metal translocating P-type atpase
FI644_RS02980	COG3336	cytochrome c oxidase
FI644_RS02995	COG0586	Pfam SNARE associated Golgi protein
FI644_RS03000	COG0305	Participates in initiation and elongation during chromosome replication
FI644_RS03020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS03030	COG1522	sequence-specific DNA binding
FI644_RS03035	COG1335	isochorismatase
FI644_RS03060	COG1444	tRNA N-acetyltransferase activity
FI644_RS03075	COG1051	belongs to the nudix hydrolase family
FI644_RS03085	COG1247	-acetyltransferase
FI644_RS03090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FI644_RS03100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS03110	COG0697	spore germination
FI644_RS03115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS03120	COG3381	protein complex oligomerization
FI644_RS03125	COG0243	molybdopterin cofactor binding
FI644_RS03130	COG0437	4 iron, 4 sulfur cluster binding
FI644_RS03140	COG1051	belongs to the nudix hydrolase family
FI644_RS03145	COG0546	phosphoglycolate phosphatase activity
FI644_RS03155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS03160	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FI644_RS03170	COG1595	DNA-templated transcription, initiation
FI644_RS03245	COG2814	Major facilitator Superfamily
FI644_RS03250	COG0789	Transcriptional regulator
FI644_RS03275	COG4974	Belongs to the 'phage' integrase family
FI644_RS03295	COG0789	Transcriptional regulator
FI644_RS03325	COG0640	Transcriptional regulator
FI644_RS03330	COG0604	alcohol dehydrogenase
FI644_RS03335	COG1595	DNA-templated transcription, initiation
FI644_RS03375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FI644_RS03380	COG2030	dehydratase
FI644_RS03405	COG0778	Nitroreductase
FI644_RS03445	COG2508	Transcriptional regulator
FI644_RS03470	COG1595	DNA-templated transcription, initiation
FI644_RS03485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FI644_RS03495	COG0697	spore germination
FI644_RS03510	COG2814	Major facilitator Superfamily
FI644_RS03515	COG0640	Transcriptional regulator
FI644_RS03530	COG2814	Major facilitator Superfamily
FI644_RS03535	COG1309	transcriptional regulator
FI644_RS03545	COG1396	sequence-specific DNA binding
FI644_RS03550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FI644_RS03560	COG0488	(ABC) transporter
FI644_RS03615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FI644_RS03620	COG0017	Asparaginyl-tRNA synthetase
FI644_RS03625	COG0412	Dienelactone hydrolase
FI644_RS03630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS03660	COG2814	Major facilitator Superfamily
FI644_RS03675	COG2378	regulation of single-species biofilm formation
FI644_RS03680	COG2318	DinB family
FI644_RS03685	COG0494	nUDIX hydrolase
FI644_RS03695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS03705	COG0456	acetyltransferase
FI644_RS03710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS03745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FI644_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS03770	COG1309	transcriptional regulator
FI644_RS03825	COG2814	Major facilitator Superfamily
FI644_RS03835	COG0494	nUDIX hydrolase
FI644_RS03855	COG1131	(ABC) transporter
FI644_RS03870	COG2801	Transposase and inactivated derivatives
FI644_RS03875	COG1609	Transcriptional regulator
FI644_RS03895	COG0583	DNA-binding transcription factor activity
FI644_RS03905	COG2808	Putative FMN-binding domain
FI644_RS03910	COG0456	acetyltransferase
FI644_RS03915	COG1846	Transcriptional regulator
FI644_RS03920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FI644_RS03940	COG2169	Transcriptional regulator
FI644_RS03945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FI644_RS03965	COG1595	DNA-templated transcription, initiation
FI644_RS04000	COG0726	polysaccharide deacetylase
FI644_RS04005	COG1408	metallophosphoesterase
FI644_RS04010	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FI644_RS04040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FI644_RS04045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FI644_RS04095	COG2207	Transcriptional regulator
FI644_RS04110	COG5002	protein histidine kinase activity
FI644_RS04115	COG0745	RESPONSE REGULATOR receiver
FI644_RS04230	COG0735	belongs to the Fur family
FI644_RS04235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FI644_RS04245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FI644_RS04250	COG4129	membrane
FI644_RS04255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS04260	COG0601	transmembrane transport
FI644_RS04265	COG0747	negative chemotaxis
FI644_RS04270	COG4608	Belongs to the ABC transporter superfamily
FI644_RS04275	COG0444	Belongs to the ABC transporter superfamily
FI644_RS04280	COG1132	(ABC) transporter
FI644_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS04310	COG1194	a g-specific adenine glycosylase
FI644_RS04315	COG1988	membrane-bound metal-dependent
FI644_RS04340	COG0300	oxidoreductase activity
FI644_RS04345	COG2137	regulation of response to DNA damage stimulus
FI644_RS04350	COG1090	epimerase
FI644_RS04370	COG2304	oxidoreductase activity
FI644_RS04375	COG1132	(ABC) transporter
FI644_RS04380	COG1132	(ABC) transporter
FI644_RS04415	COG0683	leucine binding
FI644_RS04420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FI644_RS04430	COG3314	Sporulation integral membrane protein YlbJ
FI644_RS04450	COG2807	transmembrane transport
FI644_RS04455	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FI644_RS04465	COG0109	protoheme IX farnesyltransferase activity
FI644_RS04480	COG2233	PERMEase
FI644_RS04495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FI644_RS04500	COG1447	Phosphotransferase system cellobiose-specific component IIA
FI644_RS04525	COG2188	Transcriptional regulator
FI644_RS04535	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FI644_RS04550	COG2205	protein histidine kinase activity
FI644_RS04555	COG0745	RESPONSE REGULATOR receiver
FI644_RS04560	COG2311	Membrane
FI644_RS04565	COG0668	transmembrane transport
FI644_RS04570	COG1959	2 iron, 2 sulfur cluster binding
FI644_RS04575	COG2910	NAD(P)H-binding
FI644_RS04585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FI644_RS04590	COG0300	oxidoreductase activity
FI644_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS04685	COG5301	cellulose 1,4-beta-cellobiosidase activity
FI644_RS04700	COG3299	homolog of phage Mu protein gp47
FI644_RS04705	COG3628	GPW Gp25 family protein
FI644_RS04755	COG3677	Transposase
FI644_RS04770	COG0535	radical SAM domain protein
FI644_RS04775	COG2197	response regulator
FI644_RS04780	COG4585	Histidine kinase
FI644_RS04810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI644_RS04820	COG2226	methyltransferase
FI644_RS04825	COG1053	succinate dehydrogenase
FI644_RS04830	COG1309	transcriptional regulator
FI644_RS04835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FI644_RS04840	COG1122	ATPase activity
FI644_RS04845	COG4720	Psort location CytoplasmicMembrane, score
FI644_RS04865	COG0488	(ABC) transporter
FI644_RS04875	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FI644_RS04880	COG4191	Histidine kinase
FI644_RS04900	COG1174	glycine betaine transport
FI644_RS04905	COG0517	IMP dehydrogenase activity
FI644_RS04905	COG1125	glycine betaine transport
FI644_RS04920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FI644_RS04935	COG1940	carbohydrate kinase activity
FI644_RS04940	COG3250	beta-galactosidase activity
FI644_RS04945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FI644_RS04950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FI644_RS04955	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS04965	COG0395	ABC-type sugar transport system, permease component
FI644_RS04970	COG1175	transmembrane transport
FI644_RS04980	COG2207	Transcriptional regulator
FI644_RS04980	COG4753	response regulator
FI644_RS04985	COG2972	Histidine kinase
FI644_RS04990	COG0366	Alpha amylase catalytic
FI644_RS05005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FI644_RS05010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FI644_RS05015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FI644_RS05050	COG1757	Na H antiporter
FI644_RS05055	COG0535	radical SAM domain protein
FI644_RS05065	COG0387	Pfam Sodium calcium exchanger
FI644_RS05070	COG0477	Major facilitator Superfamily
FI644_RS05075	COG2217	Heavy metal translocating P-type atpase
FI644_RS05080	COG1295	ribonuclease BN
FI644_RS05090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FI644_RS05095	COG4840	Belongs to the UPF0435 family
FI644_RS05105	COG0243	molybdopterin cofactor binding
FI644_RS05120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FI644_RS05125	COG2204	response regulator
FI644_RS05140	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FI644_RS05145	COG1396	sequence-specific DNA binding
FI644_RS05185	COG0681	Belongs to the peptidase S26 family
FI644_RS05235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FI644_RS05245	COG1215	transferase activity, transferring glycosyl groups
FI644_RS05250	COG0438	transferase activity, transferring glycosyl groups
FI644_RS05270	COG4464	protein tyrosine phosphatase activity
FI644_RS05275	COG0489	protein tyrosine kinase activity
FI644_RS05280	COG3944	biosynthesis protein
FI644_RS05285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FI644_RS05290	COG1086	Polysaccharide biosynthesis protein
FI644_RS05295	COG1408	metallophosphoesterase
FI644_RS05305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FI644_RS05310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FI644_RS05320	COG2313	pseudouridylate synthase activity
FI644_RS05325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FI644_RS05330	COG1846	Transcriptional regulator
FI644_RS05335	COG2814	Major facilitator Superfamily
FI644_RS05340	COG1360	Flagellar Motor Protein
FI644_RS05345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FI644_RS05355	COG2986	histidine ammonia-lyase
FI644_RS05365	COG2031	fatty acid transporter
FI644_RS05375	COG2309	aminopeptidase activity
FI644_RS05385	COG4145	pantothenate transmembrane transporter activity
FI644_RS05395	COG1970	mechanosensitive ion channel activity
FI644_RS05400	COG0670	Belongs to the BI1 family
FI644_RS05410	COG0312	modulator of DNA gyrase
FI644_RS05415	COG0312	modulator of DNA gyrase
FI644_RS05420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FI644_RS05425	COG2312	Erythromycin esterase
FI644_RS05440	COG1607	acyl-coa hydrolase
FI644_RS05450	COG2244	polysaccharide biosynthetic process
FI644_RS05455	COG3681	Belongs to the UPF0597 family
FI644_RS05460	COG0488	(ABC) transporter
FI644_RS05470	COG2197	response regulator
FI644_RS05475	COG4585	Histidine kinase
FI644_RS05485	COG1842	Phage shock protein A
FI644_RS05495	COG2720	vancomycin resistance protein
FI644_RS05500	COG0723	plastoquinol--plastocyanin reductase activity
FI644_RS05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FI644_RS05505	COG0513	Belongs to the DEAD box helicase family
FI644_RS05515	COG1115	amino acid carrier protein
FI644_RS05520	COG2814	Major facilitator Superfamily
FI644_RS05530	COG1595	DNA-templated transcription, initiation
FI644_RS05555	COG2706	6-phosphogluconolactonase activity
FI644_RS05560	COG0024	Methionine aminopeptidase
FI644_RS05565	COG0604	alcohol dehydrogenase
FI644_RS05610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FI644_RS05620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FI644_RS05655	COG1595	DNA-templated transcription, initiation
FI644_RS05665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FI644_RS05670	COG3162	membrane
FI644_RS05680	COG0583	DNA-binding transcription factor activity
FI644_RS05685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FI644_RS05690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FI644_RS05695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FI644_RS05700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FI644_RS05705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI644_RS05710	COG0789	Transcriptional regulator
FI644_RS05715	COG5002	protein histidine kinase activity
FI644_RS05720	COG0745	RESPONSE REGULATOR receiver
FI644_RS05735	COG0789	Transcriptional regulator
FI644_RS05740	COG1253	flavin adenine dinucleotide binding
FI644_RS05750	COG0601	transmembrane transport
FI644_RS05755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS05790	COG0697	spore germination
FI644_RS05805	COG0671	phosphoesterase, PA-phosphatase related
FI644_RS05810	COG5002	protein histidine kinase activity
FI644_RS05820	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FI644_RS05850	COG5566	PFAM Mor transcription activator
FI644_RS05865	COG2318	DinB family
FI644_RS05870	COG0372	Belongs to the citrate synthase family
FI644_RS05875	COG0583	DNA-binding transcription factor activity
FI644_RS05880	COG1132	(ABC) transporter
FI644_RS05885	COG1132	(ABC) transporter
FI644_RS05890	COG0861	Integral membrane protein TerC family
FI644_RS05905	COG0745	RESPONSE REGULATOR receiver
FI644_RS05910	COG2205	protein histidine kinase activity
FI644_RS05915	COG1131	(ABC) transporter
FI644_RS05930	COG0527	aspartate kinase activity
FI644_RS05940	COG1320	monovalent cation:proton antiporter activity
FI644_RS05945	COG2212	antiporter activity
FI644_RS05950	COG1863	multisubunit Na H antiporter MnhE subunit
FI644_RS05955	COG0651	ATP synthesis coupled electron transport
FI644_RS05960	COG1006	Multisubunit Na H antiporter MnhC subunit
FI644_RS05965	COG2111	Na H antiporter
FI644_RS05970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FI644_RS05970	COG2111	Na H antiporter
FI644_RS05980	COG0582	viral genome integration into host DNA
FI644_RS05985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FI644_RS05990	COG2205	protein histidine kinase activity
FI644_RS05990	COG2198	Histidine kinase
FI644_RS05990	COG0784	Response regulator, receiver
FI644_RS06015	COG2310	stress, protein
FI644_RS06020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FI644_RS06025	COG0673	inositol 2-dehydrogenase activity
FI644_RS06030	COG2234	aminopeptidase activity
FI644_RS06040	COG0166	Belongs to the GPI family
FI644_RS06045	COG3853	Toxic anion resistance protein (TelA)
FI644_RS06050	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FI644_RS06060	COG0626	cystathionine gamma-synthase activity
FI644_RS06070	COG2814	Major facilitator Superfamily
FI644_RS06085	COG0778	Nitroreductase
FI644_RS06090	COG1733	regulation of RNA biosynthetic process
FI644_RS06100	COG2304	oxidoreductase activity
FI644_RS06105	COG1376	ErfK ybiS ycfS ynhG family protein
FI644_RS06110	COG4974	Belongs to the 'phage' integrase family
FI644_RS06145	COG0243	molybdopterin cofactor binding
FI644_RS06155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS06160	COG1785	Belongs to the alkaline phosphatase family
FI644_RS06170	COG0363	glucosamine-6-phosphate deaminase activity
FI644_RS06175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FI644_RS06180	COG3142	Participates in the control of copper homeostasis
FI644_RS06190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FI644_RS06195	COG1263	PTS System
FI644_RS06195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FI644_RS06200	COG3711	transcriptional antiterminator
FI644_RS06205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FI644_RS06205	COG1263	PTS System
FI644_RS06205	COG2190	(PTS) system
FI644_RS06220	COG1309	transcriptional regulator
FI644_RS06225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS06230	COG2207	Transcriptional regulator
FI644_RS06245	COG0142	geranyltranstransferase activity
FI644_RS06250	COG2267	carboxylic ester hydrolase activity
FI644_RS06270	COG4807	Protein conserved in bacteria
FI644_RS06300	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FI644_RS06305	COG1120	ATPase activity
FI644_RS06310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS06315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS06320	COG1525	nuclease
FI644_RS06325	COG0534	Mate efflux family protein
FI644_RS06335	COG1404	Belongs to the peptidase S8 family
FI644_RS06350	COG1597	lipid kinase activity
FI644_RS06380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FI644_RS06395	COG1227	inorganic diphosphatase activity
FI644_RS06400	COG2070	2-Nitropropane dioxygenase
FI644_RS06420	COG3279	Response regulator of the LytR AlgR family
FI644_RS06425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FI644_RS06430	COG0154	amidase activity
FI644_RS06435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FI644_RS06440	COG5506	Protein of unknown function (DUF1694)
FI644_RS06445	COG2224	Isocitrate lyase
FI644_RS06450	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS06455	COG4851	CamS sex pheromone cAM373 precursor
FI644_RS06460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FI644_RS06465	COG0210	DNA helicase
FI644_RS06470	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FI644_RS06475	COG4496	protein, YerC YecD
FI644_RS06480	COG1470	cell adhesion involved in biofilm formation
FI644_RS06495	COG0151	Belongs to the GarS family
FI644_RS06500	COG0138	bifunctional purine biosynthesis protein purh
FI644_RS06505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FI644_RS06510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FI644_RS06515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FI644_RS06520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FI644_RS06525	COG0047	phosphoribosylformylglycinamidine synthase activity
FI644_RS06530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FI644_RS06535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FI644_RS06540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FI644_RS06545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FI644_RS06550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FI644_RS06560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FI644_RS06580	COG2190	(PTS) system
FI644_RS06580	COG1263	PTS System
FI644_RS06580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FI644_RS06585	COG2252	PERMEase
FI644_RS06595	COG1305	Transglutaminase-like
FI644_RS06600	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FI644_RS06605	COG0714	Associated with various cellular activities
FI644_RS06630	COG2304	oxidoreductase activity
FI644_RS06635	COG2076	Multidrug Resistance protein
FI644_RS06640	COG2076	Multidrug Resistance protein
FI644_RS06665	COG1595	DNA-templated transcription, initiation
FI644_RS06680	COG2814	Major facilitator Superfamily
FI644_RS06685	COG1846	Transcriptional regulator
FI644_RS06690	COG2226	methyltransferase
FI644_RS06695	COG0488	(ABC) transporter
FI644_RS06705	COG2207	Transcriptional regulator
FI644_RS06715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FI644_RS06720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FI644_RS06725	COG0647	UMP catabolic process
FI644_RS06735	COG3842	ATPase activity
FI644_RS06740	COG1840	ABC-type Fe3 transport system, periplasmic component
FI644_RS06745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI644_RS06750	COG0473	3-isopropylmalate dehydrogenase activity
FI644_RS06755	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS06760	COG4638	Rieske (2fe-2S)
FI644_RS06765	COG3829	transcription factor binding
FI644_RS06770	COG1136	(ABC) transporter
FI644_RS06780	COG1309	transcriptional regulator
FI644_RS06785	COG2205	protein histidine kinase activity
FI644_RS06790	COG0745	RESPONSE REGULATOR receiver
FI644_RS06795	COG1131	(ABC) transporter
FI644_RS06825	COG0459	protein refolding
FI644_RS06830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FI644_RS06835	COG1266	CAAX protease self-immunity
FI644_RS06845	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FI644_RS06850	COG0315	cyclic pyranopterin monophosphate synthase activity
FI644_RS06855	COG0488	(ABC) transporter
FI644_RS06865	COG0456	acetyltransferase
FI644_RS06870	COG1214	PFAM Peptidase M22, glycoprotease
FI644_RS06875	COG0802	atpase or kinase
FI644_RS06970	COG2183	response to ionizing radiation
FI644_RS06975	COG1191	sigma factor activity
FI644_RS06980	COG2172	sigma factor antagonist activity
FI644_RS06985	COG1366	Belongs to the anti-sigma-factor antagonist family
FI644_RS06990	COG2337	Toxic component of a toxin-antitoxin (TA) module
FI644_RS06995	COG0864	Transcriptional regulator
FI644_RS07005	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FI644_RS07010	COG0736	holo-[acyl-carrier-protein] synthase activity
FI644_RS07015	COG0705	Rhomboid family
FI644_RS07020	COG3290	protein histidine kinase activity
FI644_RS07020	COG0840	transmembrane signaling receptor activity
FI644_RS07025	COG3428	Bacterial PH domain
FI644_RS07030	COG3402	PFAM membrane-flanked domain
FI644_RS07035	COG0513	Belongs to the DEAD box helicase family
FI644_RS07050	COG4152	abc transporter atp-binding protein
FI644_RS07070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FI644_RS07075	COG1181	Belongs to the D-alanine--D-alanine ligase family
FI644_RS07080	COG1368	sulfuric ester hydrolase activity
FI644_RS07085	COG0659	secondary active sulfate transmembrane transporter activity
FI644_RS07090	COG0517	IMP dehydrogenase activity
FI644_RS07100	COG3708	Transcriptional regulator
FI644_RS07100	COG2207	Transcriptional regulator
FI644_RS07105	COG0346	lactoylglutathione lyase activity
FI644_RS07135	COG2096	Adenosyltransferase
FI644_RS07150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FI644_RS07155	COG1492	cobalamin metabolic process
FI644_RS07160	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FI644_RS07170	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FI644_RS07175	COG1120	ATPase activity
FI644_RS07180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS07185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS07195	COG2239	Acts as a magnesium transporter
FI644_RS07200	COG0772	Belongs to the SEDS family
FI644_RS07210	COG0783	Belongs to the Dps family
FI644_RS07220	COG4607	ABC-type enterochelin transport system periplasmic component
FI644_RS07225	COG4604	ABC transporter, ATP-binding protein
FI644_RS07230	COG4605	iron ion homeostasis
FI644_RS07235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS07245	COG4608	Belongs to the ABC transporter superfamily
FI644_RS07250	COG0791	NLP P60 protein
FI644_RS07255	COG4948	Mandelate Racemase Muconate Lactonizing
FI644_RS07260	COG1619	proteins homologs of microcin C7 resistance protein MccF
FI644_RS07265	COG4166	transmembrane transport
FI644_RS07270	COG0444	Belongs to the ABC transporter superfamily
FI644_RS07275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS07280	COG0601	transmembrane transport
FI644_RS07285	COG2362	D-Aminopeptidase
FI644_RS07295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FI644_RS07305	COG0840	transmembrane signaling receptor activity
FI644_RS07310	COG0010	Belongs to the arginase family
FI644_RS07315	COG1228	amidohydrolase
FI644_RS07320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FI644_RS07325	COG4977	sequence-specific DNA binding
FI644_RS07330	COG0739	heme binding
FI644_RS07345	COG1794	racemase activity, acting on amino acids and derivatives
FI644_RS07350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FI644_RS07365	COG1368	sulfuric ester hydrolase activity
FI644_RS07370	COG4682	membrane
FI644_RS07380	COG0640	Transcriptional regulator
FI644_RS07395	COG1131	(ABC) transporter
FI644_RS07400	COG2188	Transcriptional regulator
FI644_RS07405	COG3973	AAA domain
FI644_RS07420	COG0577	efflux transmembrane transporter activity
FI644_RS07425	COG1136	(ABC) transporter
FI644_RS07430	COG2205	protein histidine kinase activity
FI644_RS07435	COG0745	RESPONSE REGULATOR receiver
FI644_RS07470	COG1846	Transcriptional regulator
FI644_RS07575	COG3559	Exporter of polyketide antibiotics
FI644_RS07580	COG1131	(ABC) transporter
FI644_RS07585	COG1309	transcriptional regulator
FI644_RS07590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FI644_RS07600	COG2814	Major facilitator Superfamily
FI644_RS07610	COG0586	Pfam SNARE associated Golgi protein
FI644_RS07620	COG1695	Transcriptional regulator
FI644_RS07630	COG2205	protein histidine kinase activity
FI644_RS07645	COG0745	RESPONSE REGULATOR receiver
FI644_RS07655	COG3226	Transcriptional regulator
FI644_RS07695	COG0534	Mate efflux family protein
FI644_RS07715	COG2076	Multidrug Resistance protein
FI644_RS07720	COG2076	Multidrug Resistance protein
FI644_RS07725	COG1309	transcriptional regulator
FI644_RS07730	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS07745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FI644_RS07755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FI644_RS07760	COG0488	(ABC) transporter
FI644_RS07770	COG0701	Predicted permease
FI644_RS07780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FI644_RS07785	COG0523	cobalamin synthesis protein
FI644_RS07805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FI644_RS07810	COG0300	oxidoreductase activity
FI644_RS07825	COG3258	Cytochrome c
FI644_RS07830	COG0640	Transcriptional regulator
FI644_RS07835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI644_RS07845	COG1733	regulation of RNA biosynthetic process
FI644_RS07850	COG2814	Major facilitator Superfamily
FI644_RS07875	COG1846	Transcriptional regulator
FI644_RS07880	COG1380	Effector of murein hydrolase LrgA
FI644_RS07885	COG1346	cytolysis
FI644_RS07895	COG2267	carboxylic ester hydrolase activity
FI644_RS08050	COG1595	DNA-templated transcription, initiation
FI644_RS08060	COG1309	transcriptional regulator
FI644_RS08165	COG0583	DNA-binding transcription factor activity
FI644_RS08180	COG0697	spore germination
FI644_RS08185	COG1378	Sugar-specific transcriptional regulator TrmB
FI644_RS08195	COG2814	Major facilitator Superfamily
FI644_RS08205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS08210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FI644_RS08220	COG1279	arginine transmembrane transporter activity
FI644_RS08225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS08230	COG1357	PFAM Pentapeptide repeats (8 copies)
FI644_RS08235	COG0242	peptide deformylase activity
FI644_RS08250	COG0745	RESPONSE REGULATOR receiver
FI644_RS08255	COG0366	Alpha amylase catalytic
FI644_RS08260	COG1609	Transcriptional regulator
FI644_RS08275	COG1653	transport
FI644_RS08280	COG1940	carbohydrate kinase activity
FI644_RS08285	COG0366	Alpha amylase catalytic
FI644_RS08305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FI644_RS08310	COG1309	transcriptional regulator
FI644_RS08315	COG3275	phosphorelay sensor kinase activity
FI644_RS08325	COG1966	Carbon starvation protein
FI644_RS08330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FI644_RS08335	COG4978	Transcriptional regulator
FI644_RS08335	COG0789	Transcriptional regulator
FI644_RS08340	COG2814	Major facilitator Superfamily
FI644_RS08355	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS08360	COG1132	(ABC) transporter
FI644_RS08365	COG1132	(ABC) transporter
FI644_RS08390	COG2211	Major facilitator Superfamily
FI644_RS08405	COG2318	DinB family
FI644_RS08410	COG0598	Magnesium transport protein CorA
FI644_RS08415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FI644_RS08420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FI644_RS08425	COG3706	GGDEF domain
FI644_RS08430	COG2076	Multidrug Resistance protein
FI644_RS08435	COG2076	Multidrug Resistance protein
FI644_RS08445	COG0640	Transcriptional regulator
FI644_RS08450	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FI644_RS08455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FI644_RS08460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FI644_RS08470	COG0583	DNA-binding transcription factor activity
FI644_RS08475	COG0655	NAD(P)H dehydrogenase (quinone) activity
FI644_RS08480	COG0704	Plays a role in the regulation of phosphate uptake
FI644_RS08485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FI644_RS08490	COG0581	inorganic phosphate transmembrane transporter activity
FI644_RS08495	COG0573	inorganic phosphate transmembrane transporter activity
FI644_RS08500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FI644_RS08505	COG1063	alcohol dehydrogenase
FI644_RS08510	COG1309	transcriptional regulator
FI644_RS08525	COG0028	Belongs to the TPP enzyme family
FI644_RS08535	COG3118	belongs to the thioredoxin family
FI644_RS08540	COG0789	Transcriptional regulator
FI644_RS08550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FI644_RS08555	COG0628	permease
FI644_RS08575	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FI644_RS08580	COG2508	Transcriptional regulator
FI644_RS08585	COG1335	isochorismatase
FI644_RS08595	COG1494	fructose-1,6-bisphosphatase
FI644_RS08620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FI644_RS08625	COG1757	Na H antiporter
FI644_RS08650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FI644_RS08665	COG1131	(ABC) transporter
FI644_RS08685	COG3850	Histidine kinase
FI644_RS08685	COG5002	protein histidine kinase activity
FI644_RS08690	COG0693	protein deglycase activity
FI644_RS08705	COG2267	carboxylic ester hydrolase activity
FI644_RS08725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FI644_RS08760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FI644_RS08765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FI644_RS08770	COG4856	YbbR-like protein
FI644_RS08775	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FI644_RS08780	COG5662	AntiSigma factor
FI644_RS08785	COG1595	DNA-templated transcription, initiation
FI644_RS08855	COG0726	polysaccharide deacetylase
FI644_RS08860	COG2194	sulfuric ester hydrolase activity
FI644_RS08870	COG0489	protein tyrosine kinase activity
FI644_RS08875	COG0860	N-Acetylmuramoyl-L-alanine amidase
FI644_RS08895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FI644_RS08900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FI644_RS08910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FI644_RS08915	COG1122	ATPase activity
FI644_RS08920	COG1122	ATPase activity
FI644_RS08925	COG0203	ribosomal protein L17
FI644_RS08930	COG0202	RNA polymerase activity
FI644_RS08935	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FI644_RS08940	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FI644_RS08945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FI644_RS08950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FI644_RS08955	COG0024	Methionine aminopeptidase
FI644_RS08960	COG0563	adenylate kinase activity
FI644_RS08965	COG0201	protein transport
FI644_RS08975	COG1841	ribosomal large subunit assembly
FI644_RS08980	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FI644_RS08985	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FI644_RS08990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FI644_RS09005	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FI644_RS09010	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FI644_RS09015	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FI644_RS09020	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FI644_RS09025	COG0255	Belongs to the universal ribosomal protein uL29 family
FI644_RS09030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FI644_RS09035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FI644_RS09045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FI644_RS09050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FI644_RS09060	COG0088	Forms part of the polypeptide exit tunnel
FI644_RS09070	COG0051	transcription antitermination factor activity, RNA binding
FI644_RS09075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FI644_RS09080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FI644_RS09090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FI644_RS09095	COG1358	cellular component organization or biogenesis
FI644_RS09100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FI644_RS09105	COG0085	RNA polymerase activity
FI644_RS09110	COG2813	Specifically methylates the guanine in position
FI644_RS09115	COG0222	ribosome binding
FI644_RS09125	COG0081	regulation of translation
FI644_RS09130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FI644_RS09135	COG0250	Participates in transcription elongation, termination and antitermination
FI644_RS09140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FI644_RS09145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FI644_RS09155	COG3688	RNA-binding protein containing a PIN domain
FI644_RS09160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FI644_RS09170	COG0215	cysteine-tRNA ligase activity
FI644_RS09175	COG1045	serine acetyltransferase
FI644_RS09180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FI644_RS09185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FI644_RS09190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FI644_RS09195	COG4956	integral membrane protein (PIN domain superfamily)
FI644_RS09200	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FI644_RS09205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FI644_RS09210	COG0542	response to heat
FI644_RS09215	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FI644_RS09220	COG3880	PFAM UvrB UvrC protein
FI644_RS09305	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FI644_RS09310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FI644_RS09315	COG1396	sequence-specific DNA binding
FI644_RS09320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FI644_RS09325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FI644_RS09330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FI644_RS09335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FI644_RS09340	COG0512	Glutamine amidotransferase of anthranilate synthase
FI644_RS09350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FI644_RS09355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FI644_RS09360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FI644_RS09365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FI644_RS09370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FI644_RS09375	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FI644_RS09385	COG0515	serine threonine protein kinase
FI644_RS09390	COG2304	oxidoreductase activity
FI644_RS09395	COG2208	phosphoserine phosphatase activity
FI644_RS09400	COG1098	S1 RNA binding domain
FI644_RS09405	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FI644_RS09420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FI644_RS09425	COG3956	TIGRFAM MazG family protein
FI644_RS09430	COG2244	polysaccharide biosynthetic process
FI644_RS09435	COG2002	toxin-antitoxin pair type II binding
FI644_RS09440	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FI644_RS09450	COG0193	aminoacyl-tRNA hydrolase activity
FI644_RS09455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FI644_RS09475	COG0251	oxidation-reduction process
FI644_RS09480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FI644_RS09495	COG4466	Protein conserved in bacteria
FI644_RS09505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FI644_RS09515	COG3584	3D domain protein
FI644_RS09515	COG3583	domain protein
FI644_RS09520	COG0084	hydrolase, TatD family'
FI644_RS09530	COG2002	toxin-antitoxin pair type II binding
FI644_RS09535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FI644_RS09545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FI644_RS09550	COG4467	Involved in initiation control of chromosome replication
FI644_RS09555	COG1774	PSP1 C-terminal conserved region
FI644_RS09560	COG0470	DNA polymerase III
FI644_RS09565	COG1728	Protein conserved in bacteria
FI644_RS09570	COG3870	Protein conserved in bacteria
FI644_RS09575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FI644_RS09580	COG1982	Orn Lys Arg decarboxylase major
FI644_RS09625	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FI644_RS09630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FI644_RS09635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FI644_RS09645	COG0590	tRNA wobble adenosine to inosine editing
FI644_RS09650	COG3858	chitin binding
FI644_RS09650	COG1388	LysM domain
FI644_RS09655	COG1428	Deoxynucleoside kinase
FI644_RS09660	COG1428	Deoxynucleoside kinase
FI644_RS09675	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FI644_RS09690	COG0516	GMP reductase activity
FI644_RS09690	COG0517	IMP dehydrogenase activity
FI644_RS09725	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FI644_RS09730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FI644_RS09735	COG0187	DNA topoisomerase II activity
FI644_RS09745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FI644_RS09750	COG2501	S4 domain
FI644_RS09755	COG0592	DNA-directed DNA polymerase activity
FI644_RS09765	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FI644_RS09770	COG0594	ribonuclease P activity
FI644_RS09780	COG1847	R3H domain protein
FI644_RS09785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FI644_RS09790	COG0445	tRNA wobble uridine modification
FI644_RS09795	COG0357	Ribosomal RNA small subunit methyltransferase G
FI644_RS09800	COG1475	DNA binding
FI644_RS09805	COG1192	Involved in chromosome partitioning
FI644_RS09810	COG1475	DNA binding
FI644_RS09825	COG4481	Protein conserved in bacteria
FI644_RS09830	COG0012	GTP binding
FI644_RS09840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS09845	COG0360	Binds together with S18 to 16S ribosomal RNA
FI644_RS09850	COG0629	single-stranded DNA binding
FI644_RS09855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FI644_RS09860	COG0840	transmembrane signaling receptor activity
FI644_RS09870	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FI644_RS09875	COG0359	binds to the 23S rRNA
FI644_RS09880	COG0305	Participates in initiation and elongation during chromosome replication
FI644_RS09905	COG0741	lytic transglycosylase activity
FI644_RS09905	COG1196	nuclear chromosome segregation
FI644_RS09905	COG0739	heme binding
FI644_RS09910	COG0745	RESPONSE REGULATOR receiver
FI644_RS09915	COG5002	protein histidine kinase activity
FI644_RS09920	COG4863	YycH protein
FI644_RS09925	COG4853	Protein conserved in bacteria
FI644_RS09930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FI644_RS09935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI644_RS09945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FI644_RS09980	COG0583	DNA-binding transcription factor activity
FI644_RS10000	COG0778	Nitroreductase
FI644_RS10010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS10015	COG2814	Major facilitator Superfamily
FI644_RS10020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI644_RS10040	COG5002	protein histidine kinase activity
FI644_RS10060	COG0477	Major facilitator Superfamily
FI644_RS10065	COG0833	amino acid
FI644_RS10080	COG0693	protein deglycase activity
FI644_RS10085	COG0693	protein deglycase activity
FI644_RS10085	COG0753	catalase activity
FI644_RS10095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FI644_RS10100	COG0662	Cupin 2, conserved barrel domain protein
FI644_RS10100	COG2207	Transcriptional regulator
FI644_RS10105	COG0697	spore germination
FI644_RS10110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FI644_RS10125	COG0395	ABC-type sugar transport system, permease component
FI644_RS10140	COG2723	6-phospho-beta-galactosidase activity
FI644_RS10145	COG0673	inositol 2-dehydrogenase activity
FI644_RS10155	COG2391	methyltransferase activity
FI644_RS10160	COG3634	alkyl hydroperoxide reductase activity
FI644_RS10165	COG0450	alkyl hydroperoxide reductase
FI644_RS10170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FI644_RS10175	COG1404	Belongs to the peptidase S8 family
FI644_RS10205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FI644_RS10235	COG0733	neurotransmitter:sodium symporter activity
FI644_RS10250	COG1309	transcriptional regulator
FI644_RS10280	COG1349	DNA-binding transcription factor activity
FI644_RS10285	COG3842	ATPase activity
FI644_RS10310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FI644_RS10330	COG1070	Carbohydrate kinase
FI644_RS10345	COG4191	Histidine kinase
FI644_RS10350	COG0784	Response regulator, receiver
FI644_RS10360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FI644_RS10365	COG0402	S-adenosylhomocysteine deaminase activity
FI644_RS10375	COG2169	Transcriptional regulator
FI644_RS10380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FI644_RS10385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FI644_RS10395	COG0583	DNA-binding transcription factor activity
FI644_RS10400	COG1607	acyl-coa hydrolase
FI644_RS10430	COG1070	Carbohydrate kinase
FI644_RS10455	COG1879	ABC-type sugar transport system periplasmic component
FI644_RS10460	COG1830	Aldolase
FI644_RS10465	COG0693	protein deglycase activity
FI644_RS10475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FI644_RS10485	COG0840	transmembrane signaling receptor activity
FI644_RS10495	COG4166	transmembrane transport
FI644_RS10520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI644_RS10525	COG0765	amino acid transport
FI644_RS10530	COG1126	abc transporter atp-binding protein
FI644_RS10535	COG3290	protein histidine kinase activity
FI644_RS10535	COG0840	transmembrane signaling receptor activity
FI644_RS10550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS10555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS10560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS10565	COG1120	ATPase activity
FI644_RS10570	COG0492	ferredoxin-NADP+ reductase activity
FI644_RS10580	COG2746	aminoglycoside 3-N-acetyltransferase activity
FI644_RS10625	COG4191	Histidine kinase
FI644_RS10630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FI644_RS10645	COG3314	Sporulation integral membrane protein YlbJ
FI644_RS10660	COG1131	(ABC) transporter
FI644_RS10665	COG1132	(ABC) transporter
FI644_RS10670	COG0789	Transcriptional regulator
FI644_RS10670	COG4978	Transcriptional regulator
FI644_RS10685	COG0561	phosphatase activity
FI644_RS10695	COG2095	MarC family integral membrane protein
FI644_RS10710	COG1131	(ABC) transporter
FI644_RS10730	COG4263	nitrous-oxide reductase activity
FI644_RS10755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FI644_RS10760	COG0351	phosphomethylpyrimidine kinase
FI644_RS10765	COG0745	RESPONSE REGULATOR receiver
FI644_RS10770	COG5002	protein histidine kinase activity
FI644_RS10820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FI644_RS10845	COG0746	molybdenum cofactor guanylyltransferase activity
FI644_RS10850	COG0303	'Molybdopterin
FI644_RS10855	COG1910	domain protein
FI644_RS10860	COG0314	molybdopterin synthase activity
FI644_RS10870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FI644_RS10885	COG2363	Small membrane protein
FI644_RS10895	COG3253	May function as heme-dependent peroxidase
FI644_RS10900	COG0280	phosphate acetyltransferase
FI644_RS10915	COG4844	belongs to the
FI644_RS10920	COG1078	dGTPase activity
FI644_RS10925	COG3465	dGTPase activity
FI644_RS10935	COG1994	Peptidase M50
FI644_RS10945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FI644_RS10950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FI644_RS10955	COG0010	Belongs to the arginase family
FI644_RS10960	COG4506	Protein conserved in bacteria
FI644_RS10965	COG0018	arginyl-trna synthetase
FI644_RS10970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FI644_RS10975	COG2181	nitrate reductase activity
FI644_RS10975	COG0247	lactate metabolic process
FI644_RS10980	COG0183	Belongs to the thiolase family
FI644_RS10985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI644_RS10990	COG1960	acyl-CoA dehydrogenase activity
FI644_RS10995	COG1960	acyl-CoA dehydrogenase activity
FI644_RS11005	COG1703	isobutyryl-CoA mutase activity
FI644_RS11005	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FI644_RS11005	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FI644_RS11015	COG3343	RNA polymerase activity
FI644_RS11020	COG0504	CTP synthase activity
FI644_RS11025	COG4821	SIS domain
FI644_RS11030	COG2204	response regulator
FI644_RS11035	COG0191	fructose-bisphosphate aldolase activity
FI644_RS11040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FI644_RS11045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FI644_RS11050	COG1494	fructose-1,6-bisphosphatase
FI644_RS11055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FI644_RS11065	COG1435	thymidine kinase activity
FI644_RS11070	COG0697	spore germination
FI644_RS11075	COG1802	Transcriptional regulator
FI644_RS11080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FI644_RS11085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FI644_RS11105	COG0009	L-threonylcarbamoyladenylate synthase
FI644_RS11110	COG1971	Probably functions as a manganese efflux pump
FI644_RS11120	COG0840	transmembrane signaling receptor activity
FI644_RS11125	COG0698	ribose 5-phosphate isomerase
FI644_RS11140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FI644_RS11145	COG1404	Belongs to the peptidase S8 family
FI644_RS11155	COG0356	it plays a direct role in the translocation of protons across the membrane
FI644_RS11160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FI644_RS11165	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FI644_RS11170	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FI644_RS11175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FI644_RS11180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FI644_RS11185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FI644_RS11190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FI644_RS11195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FI644_RS11200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FI644_RS11205	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FI644_RS11210	COG0649	NAD binding
FI644_RS11215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FI644_RS11225	COG0839	Belongs to the complex I subunit 6 family
FI644_RS11235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FI644_RS11240	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FI644_RS11245	COG1007	ATP synthesis coupled electron transport
FI644_RS11255	COG1309	transcriptional regulator
FI644_RS11260	COG4836	Membrane
FI644_RS11280	COG2385	sporulation resulting in formation of a cellular spore
FI644_RS11290	COG0739	heme binding
FI644_RS11295	COG0840	transmembrane signaling receptor activity
FI644_RS11300	COG1609	Transcriptional regulator
FI644_RS11305	COG1077	Cell shape determining protein MreB Mrl
FI644_RS11310	COG4786	Flagellar basal body rod
FI644_RS11315	COG4786	Flagellar basal body rod
FI644_RS11340	COG0629	single-stranded DNA binding
FI644_RS11350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FI644_RS11355	COG4715	Zinc finger, swim domain protein
FI644_RS11360	COG2378	regulation of single-species biofilm formation
FI644_RS11365	COG3708	Transcriptional regulator
FI644_RS11375	COG2234	aminopeptidase activity
FI644_RS11380	COG0606	chelatase, subunit chli
FI644_RS11385	COG0758	DNA mediated transformation
FI644_RS11390	COG3878	Protein conserved in bacteria
FI644_RS11395	COG0662	Cupin 2, conserved barrel domain protein
FI644_RS11415	COG1376	ErfK ybiS ycfS ynhG family protein
FI644_RS11420	COG3409	Peptidoglycan-binding domain 1 protein
FI644_RS11420	COG0793	Belongs to the peptidase S41A family
FI644_RS11525	COG0444	Belongs to the ABC transporter superfamily
FI644_RS11530	COG4608	Belongs to the ABC transporter superfamily
FI644_RS11545	COG0601	transmembrane transport
FI644_RS11550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS11555	COG2267	carboxylic ester hydrolase activity
FI644_RS11565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS11580	COG1335	isochorismatase
FI644_RS11590	COG1388	LysM domain
FI644_RS11590	COG0791	NLP P60 protein
FI644_RS11615	COG4145	pantothenate transmembrane transporter activity
FI644_RS11620	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FI644_RS11640	COG1737	Transcriptional regulator
FI644_RS11650	COG0601	transmembrane transport
FI644_RS11660	COG0444	Belongs to the ABC transporter superfamily
FI644_RS11665	COG4608	Belongs to the ABC transporter superfamily
FI644_RS11670	COG1473	amidohydrolase
FI644_RS11675	COG4948	Mandelate Racemase Muconate Lactonizing
FI644_RS11680	COG0444	Belongs to the ABC transporter superfamily
FI644_RS11685	COG4608	Belongs to the ABC transporter superfamily
FI644_RS11690	COG1414	Transcriptional regulator
FI644_RS11695	COG0747	negative chemotaxis
FI644_RS11705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS11715	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FI644_RS11720	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FI644_RS11730	COG1984	allophanate hydrolase subunit 2
FI644_RS11755	COG1914	H( )-stimulated, divalent metal cation uptake system
FI644_RS11770	COG1129	ABC transporter
FI644_RS11775	COG1172	Belongs to the binding-protein-dependent transport system permease family
FI644_RS11780	COG0159	tryptophan synthase activity
FI644_RS11785	COG1070	Carbohydrate kinase
FI644_RS11795	COG3852	Histidine kinase
FI644_RS11800	COG5001	Diguanylate cyclase
FI644_RS11815	COG1840	ABC-type Fe3 transport system, periplasmic component
FI644_RS11820	COG3842	ATPase activity
FI644_RS11835	COG0165	Argininosuccinate lyase
FI644_RS11845	COG1073	alpha beta
FI644_RS11850	COG2814	Major facilitator Superfamily
FI644_RS11860	COG5002	protein histidine kinase activity
FI644_RS11875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FI644_RS11880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FI644_RS11940	COG0737	Belongs to the 5'-nucleotidase family
FI644_RS11960	COG1404	Belongs to the peptidase S8 family
FI644_RS11980	COG1388	LysM domain
FI644_RS11980	COG0791	NLP P60 protein
FI644_RS11990	COG0653	protein targeting
FI644_RS11995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FI644_RS12010	COG0673	inositol 2-dehydrogenase activity
FI644_RS12030	COG0482	sulfurtransferase activity
FI644_RS12050	COG0438	transferase activity, transferring glycosyl groups
FI644_RS12055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FI644_RS12065	COG2247	cell wall binding repeat
FI644_RS12065	COG2385	sporulation resulting in formation of a cellular spore
FI644_RS12075	COG0860	N-Acetylmuramoyl-L-alanine amidase
FI644_RS12075	COG3103	Sh3 type 3 domain protein
FI644_RS12075	COG4991	sh3 domain protein
FI644_RS12080	COG1316	TRANSCRIPTIONal
FI644_RS12085	COG1739	Uncharacterized protein family UPF0029
FI644_RS12090	COG4585	Histidine kinase
FI644_RS12095	COG2197	response regulator
FI644_RS12110	COG1307	EDD domain protein, DegV family
FI644_RS12115	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FI644_RS12120	COG1040	competence protein
FI644_RS12140	COG1256	bacterial-type flagellum assembly
FI644_RS12140	COG4786	Flagellar basal body rod
FI644_RS12145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FI644_RS12160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FI644_RS12165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FI644_RS12170	COG0463	Glycosyl transferase, family 2
FI644_RS12170	COG0457	Tetratricopeptide repeat
FI644_RS12175	COG0438	transferase activity, transferring glycosyl groups
FI644_RS12175	COG1216	Glycosyl transferase, family 2
FI644_RS12200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FI644_RS12215	COG1091	dTDP-4-dehydrorhamnose reductase activity
FI644_RS12220	COG0457	Tetratricopeptide repeat
FI644_RS12220	COG0463	Glycosyl transferase, family 2
FI644_RS12225	COG1334	flagellar protein FlaG
FI644_RS12230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FI644_RS12235	COG1516	flagellar protein fliS
FI644_RS12290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS12300	COG2884	Cell division ATP-binding protein ftsE
FI644_RS12305	COG2177	Part of the ABC transporter FtsEX involved in
FI644_RS12310	COG0793	Belongs to the peptidase S41A family
FI644_RS12310	COG3409	Peptidoglycan-binding domain 1 protein
FI644_RS12325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS12330	COG1120	ATPase activity
FI644_RS12335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS12340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI644_RS12420	COG0745	RESPONSE REGULATOR receiver
FI644_RS12425	COG2205	protein histidine kinase activity
FI644_RS12430	COG1131	(ABC) transporter
FI644_RS12450	COG2608	mercury ion transmembrane transporter activity
FI644_RS12455	COG2217	Heavy metal translocating P-type atpase
FI644_RS12460	COG0697	spore germination
FI644_RS12465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FI644_RS12470	COG2011	ABC-type metal ion transport system permease component
FI644_RS12475	COG1464	Belongs to the NlpA lipoprotein family
FI644_RS12490	COG4897	Protein conserved in bacteria
FI644_RS12495	COG0556	nucleotide-excision repair
FI644_RS12500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FI644_RS12505	COG3595	metallopeptidase activity
FI644_RS12510	COG1950	PFAM Membrane protein of
FI644_RS12520	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FI644_RS12530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FI644_RS12540	COG0110	maltose O-acetyltransferase activity
FI644_RS12545	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FI644_RS12550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FI644_RS12555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FI644_RS12560	COG0131	Imidazoleglycerol-phosphate dehydratase
FI644_RS12565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FI644_RS12570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FI644_RS12575	COG0107	imidazoleglycerol-phosphate synthase activity
FI644_RS12580	COG0140	phosphoribosyl-ATP diphosphatase activity
FI644_RS12580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FI644_RS12590	COG0457	Tetratricopeptide repeat
FI644_RS12595	COG0492	ferredoxin-NADP+ reductase activity
FI644_RS12600	COG1051	belongs to the nudix hydrolase family
FI644_RS12605	COG1660	Displays ATPase and GTPase activities
FI644_RS12610	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FI644_RS12615	COG1481	regulation of sporulation
FI644_RS12620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FI644_RS12625	COG0740	serine-type endopeptidase activity
FI644_RS12685	COG1595	DNA-templated transcription, initiation
FI644_RS12695	COG0456	acetyltransferase
FI644_RS12725	COG2176	DNA-directed DNA polymerase activity
FI644_RS12730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FI644_RS12740	COG2390	Transcriptional regulator
FI644_RS12750	COG0126	phosphoglycerate kinase activity
FI644_RS12760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FI644_RS12775	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FI644_RS12780	COG1647	Serine aminopeptidase, S33
FI644_RS12785	COG0557	exoribonuclease II activity
FI644_RS12790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FI644_RS12835	COG1132	(ABC) transporter
FI644_RS12885	COG1378	Sugar-specific transcriptional regulator TrmB
FI644_RS12895	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FI644_RS12985	COG2814	Major facilitator Superfamily
FI644_RS13005	COG2211	Major facilitator Superfamily
FI644_RS13020	COG4974	Belongs to the 'phage' integrase family
FI644_RS13025	COG1329	Transcriptional regulator
FI644_RS13040	COG0346	lactoylglutathione lyase activity
FI644_RS13045	COG2816	NAD+ diphosphatase activity
FI644_RS13060	COG0671	phosphoesterase, PA-phosphatase related
FI644_RS13080	COG0456	acetyltransferase
FI644_RS13110	COG0864	Transcriptional regulator
FI644_RS13115	COG3835	regulator
FI644_RS13125	COG0402	S-adenosylhomocysteine deaminase activity
FI644_RS13130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FI644_RS13140	COG0549	Belongs to the carbamate kinase family
FI644_RS13145	COG1301	dicarboxylic acid transport
FI644_RS13155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS13160	COG0789	Transcriptional regulator
FI644_RS13175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FI644_RS13200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FI644_RS13210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI644_RS13220	COG5002	protein histidine kinase activity
FI644_RS13220	COG3850	Histidine kinase
FI644_RS13225	COG0402	S-adenosylhomocysteine deaminase activity
FI644_RS13250	COG0697	spore germination
FI644_RS13255	COG1120	ATPase activity
FI644_RS13260	COG0492	ferredoxin-NADP+ reductase activity
FI644_RS13265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS13270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS13275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS13285	COG1309	transcriptional regulator
FI644_RS13290	COG1309	transcriptional regulator
FI644_RS13305	COG2198	Histidine kinase
FI644_RS13305	COG5002	protein histidine kinase activity
FI644_RS13305	COG0784	Response regulator, receiver
FI644_RS13315	COG2200	EAL domain
FI644_RS13320	COG3279	Response regulator of the LytR AlgR family
FI644_RS13325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI644_RS13330	COG1846	Transcriptional regulator
FI644_RS13335	COG2409	Drug exporters of the RND superfamily
FI644_RS13335	COG1033	growth of symbiont in host cell
FI644_RS13355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI644_RS13360	COG0765	amino acid transport
FI644_RS13365	COG1126	abc transporter atp-binding protein
FI644_RS13375	COG3842	ATPase activity
FI644_RS13390	COG1910	domain protein
FI644_RS13405	COG0772	Belongs to the SEDS family
FI644_RS13425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS13430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS13435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS13440	COG1120	ATPase activity
FI644_RS13460	COG1024	Enoyl-CoA hydratase
FI644_RS13460	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI644_RS13465	COG0183	Belongs to the thiolase family
FI644_RS13470	COG1960	acyl-CoA dehydrogenase activity
FI644_RS13475	COG1393	Belongs to the ArsC family
FI644_RS13480	COG0509	glycine decarboxylation via glycine cleavage system
FI644_RS13490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FI644_RS13495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS13510	COG2873	o-acetylhomoserine
FI644_RS13515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FI644_RS13520	COG2011	ABC-type metal ion transport system permease component
FI644_RS13525	COG1464	Belongs to the NlpA lipoprotein family
FI644_RS13535	COG0396	ATPase activity
FI644_RS13540	COG0719	Fe-S assembly protein
FI644_RS13545	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FI644_RS13550	COG0822	iron-sulfur transferase activity
FI644_RS13555	COG0719	Fe-S assembly protein
FI644_RS13560	COG1801	Protein of unknown function DUF72
FI644_RS13565	COG3377	Domain of unknown function (DUF1805)
FI644_RS13575	COG1757	Na H antiporter
FI644_RS13585	COG0559	Belongs to the binding-protein-dependent transport system permease family
FI644_RS13595	COG0411	ABC transporter
FI644_RS13605	COG0739	heme binding
FI644_RS13610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FI644_RS13620	COG4470	Protein conserved in bacteria
FI644_RS13635	COG5001	Diguanylate cyclase
FI644_RS13635	COG3300	MHYT domain
FI644_RS13640	COG2445	Protein of unknown function DUF86
FI644_RS13645	COG0647	UMP catabolic process
FI644_RS13650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FI644_RS13655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FI644_RS13660	COG0460	homoserine dehydrogenase
FI644_RS13665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FI644_RS13675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FI644_RS13680	COG4837	Protein of unknown function (DUF1462)
FI644_RS13685	COG1252	NADH dehydrogenase
FI644_RS13700	COG0316	Belongs to the HesB IscA family
FI644_RS13710	COG1252	NADH dehydrogenase
FI644_RS13725	COG3584	3D domain protein
FI644_RS13730	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FI644_RS13740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FI644_RS13745	COG2056	Na+-H+ antiporter family
FI644_RS13750	COG0789	Transcriptional regulator
FI644_RS13755	COG3243	poly(R)-hydroxyalkanoic acid synthase
FI644_RS13765	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS13770	COG0686	Belongs to the AlaDH PNT family
FI644_RS13775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FI644_RS13790	COG2050	protein possibly involved in aromatic compounds catabolism
FI644_RS13795	COG1320	monovalent cation:proton antiporter activity
FI644_RS13800	COG2212	antiporter activity
FI644_RS13805	COG1863	multisubunit Na H antiporter MnhE subunit
FI644_RS13810	COG0651	ATP synthesis coupled electron transport
FI644_RS13815	COG1006	Multisubunit Na H antiporter MnhC subunit
FI644_RS13820	COG2111	Na H antiporter
FI644_RS13825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FI644_RS13825	COG2111	Na H antiporter
FI644_RS13845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FI644_RS13850	COG5018	Exonuclease
FI644_RS13865	COG2032	superoxide dismutase activity
FI644_RS13870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FI644_RS13880	COG2267	carboxylic ester hydrolase activity
FI644_RS13885	COG1098	S1 RNA binding domain
FI644_RS13890	COG3829	transcription factor binding
FI644_RS13895	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS13900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FI644_RS13905	COG1979	alcohol dehydrogenase
FI644_RS13915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FI644_RS13955	COG2031	fatty acid transporter
FI644_RS13960	COG0840	transmembrane signaling receptor activity
FI644_RS13965	COG1113	amino acid transport
FI644_RS13995	COG1595	DNA-templated transcription, initiation
FI644_RS14000	COG4412	M6 family metalloprotease domain protein
FI644_RS14000	COG1404	Belongs to the peptidase S8 family
FI644_RS14010	COG0840	transmembrane signaling receptor activity
FI644_RS14040	COG0582	viral genome integration into host DNA
FI644_RS14070	COG2801	Transposase and inactivated derivatives
FI644_RS14100	COG0596	Alpha beta hydrolase
FI644_RS14110	COG0584	glycerophosphoryl diester phosphodiesterase
FI644_RS14130	COG2801	Transposase and inactivated derivatives
FI644_RS14150	COG2814	Major facilitator Superfamily
FI644_RS14175	COG1278	Cold shock
FI644_RS14185	COG0596	Alpha beta hydrolase
FI644_RS14215	COG2814	Major facilitator Superfamily
FI644_RS14285	COG2814	Major facilitator Superfamily
FI644_RS14300	COG0582	viral genome integration into host DNA
FI644_RS14355	COG5484	DNA packaging
FI644_RS14385	COG0582	viral genome integration into host DNA
FI644_RS14425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FI644_RS14505	COG0006	proline dipeptidase activity
FI644_RS14515	COG1522	sequence-specific DNA binding
FI644_RS14530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FI644_RS14570	COG3290	protein histidine kinase activity
FI644_RS14570	COG3829	transcription factor binding
FI644_RS14575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FI644_RS14580	COG3938	Belongs to the proline racemase family
FI644_RS14590	COG1115	amino acid carrier protein
FI644_RS14595	COG0601	transmembrane transport
FI644_RS14600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS14615	COG0006	proline dipeptidase activity
FI644_RS14620	COG4166	transmembrane transport
FI644_RS14625	COG1285	pathogenesis
FI644_RS14635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS14640	COG3189	MarR family transcriptional regulator
FI644_RS14770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FI644_RS14775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FI644_RS14780	COG0297	glycogen (starch) synthase activity
FI644_RS14785	COG0058	SHG alpha-glucan phosphorylase activity
FI644_RS14790	COG1834	amidinotransferase
FI644_RS14795	COG1575	Belongs to the MenA family. Type 1 subfamily
FI644_RS14800	COG1169	isochorismate synthase
FI644_RS14805	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FI644_RS14810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FI644_RS14815	COG0318	PFAM AMP-dependent synthetase and ligase
FI644_RS14830	COG0288	reversible hydration of carbon dioxide
FI644_RS14835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FI644_RS14840	COG1854	S-ribosylhomocysteine lyase activity
FI644_RS14850	COG0783	Belongs to the Dps family
FI644_RS14870	COG0494	nUDIX hydrolase
FI644_RS14880	COG0477	Major facilitator Superfamily
FI644_RS14895	COG0436	Aminotransferase
FI644_RS14900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FI644_RS14905	COG0174	glutamine synthetase
FI644_RS14910	COG0367	asparagine synthase
FI644_RS14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI644_RS14920	COG1116	anion transmembrane transporter activity
FI644_RS14925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI644_RS14930	COG1506	peptidase
FI644_RS14945	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FI644_RS14950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FI644_RS14955	COG2267	carboxylic ester hydrolase activity
FI644_RS14965	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FI644_RS14970	COG1242	4 iron, 4 sulfur cluster binding
FI644_RS15015	COG4555	ABC transporter
FI644_RS15025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FI644_RS15035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS15045	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FI644_RS15050	COG2814	Major facilitator Superfamily
FI644_RS15065	COG2610	gluconate transmembrane transporter activity
FI644_RS15070	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS15075	COG0495	leucyl-tRNA aminoacylation
FI644_RS15080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FI644_RS15095	COG2081	HI0933 family
FI644_RS15100	COG0425	Belongs to the sulfur carrier protein TusA family
FI644_RS15125	COG2244	polysaccharide biosynthetic process
FI644_RS15130	COG1187	pseudouridine synthase activity
FI644_RS15135	COG1349	DNA-binding transcription factor activity
FI644_RS15140	COG1131	(ABC) transporter
FI644_RS15145	COG4473	ABC transporter
FI644_RS15150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FI644_RS15170	COG1597	lipid kinase activity
FI644_RS15175	COG1523	belongs to the glycosyl hydrolase 13 family
FI644_RS15180	COG0510	thiamine kinase activity
FI644_RS15190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FI644_RS15195	COG1024	Enoyl-CoA hydratase
FI644_RS15200	COG3290	protein histidine kinase activity
FI644_RS15200	COG3829	transcription factor binding
FI644_RS15205	COG1024	Enoyl-CoA hydratase
FI644_RS15215	COG1024	Enoyl-CoA hydratase
FI644_RS15220	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI644_RS15240	COG0659	secondary active sulfate transmembrane transporter activity
FI644_RS15245	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS15255	COG1363	Peptidase, m42
FI644_RS15260	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FI644_RS15270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS15275	COG4848	Belongs to the UPF0354 family
FI644_RS15280	COG1674	ftsk spoiiie
FI644_RS15280	COG1674	ftsk spoiiie
FI644_RS15290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FI644_RS15295	COG2309	aminopeptidase activity
FI644_RS15300	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FI644_RS15305	COG4980	gas vesicle protein
FI644_RS15310	COG3118	belongs to the thioredoxin family
FI644_RS15320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FI644_RS15320	COG1605	Chorismate mutase
FI644_RS15325	COG1609	Transcriptional regulator
FI644_RS15340	COG0123	including yeast histone deacetylase and acetoin utilization protein
FI644_RS15345	COG0517	IMP dehydrogenase activity
FI644_RS15350	COG0454	-acetyltransferase
FI644_RS15355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FI644_RS15370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FI644_RS15380	COG2203	Gaf domain
FI644_RS15380	COG2199	diguanylate cyclase activity
FI644_RS15385	COG0626	cystathionine gamma-synthase activity
FI644_RS15390	COG1956	GAF domain-containing protein
FI644_RS15395	COG1309	transcriptional regulator
FI644_RS15400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FI644_RS15405	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FI644_RS15410	COG1114	Component of the transport system for branched-chain amino acids
FI644_RS15415	COG1114	Component of the transport system for branched-chain amino acids
FI644_RS15420	COG1104	cysteine desulfurase activity
FI644_RS15425	COG0301	tRNA thio-modification
FI644_RS15435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FI644_RS15440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FI644_RS15445	COG2962	Rard protein
FI644_RS15450	COG4187	Peptidase family M20/M25/M40
FI644_RS15455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FI644_RS15460	COG0616	signal peptide processing
FI644_RS15465	COG1714	RDD family
FI644_RS15475	COG3874	Sporulation protein YtfJ
FI644_RS15480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FI644_RS15485	COG0827	DNA restriction-modification system
FI644_RS15490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FI644_RS15500	COG0521	Mo-molybdopterin cofactor biosynthetic process
FI644_RS15510	COG0137	argininosuccinate synthase activity
FI644_RS15515	COG0165	Argininosuccinate lyase
FI644_RS15520	COG0589	response to stress
FI644_RS15525	COG0006	proline dipeptidase activity
FI644_RS15530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FI644_RS15540	COG4109	DRTGG domain
FI644_RS15550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FI644_RS15565	COG0587	DNA-directed DNA polymerase activity
FI644_RS15570	COG0281	malic enzyme
FI644_RS15575	COG1725	Transcriptional regulator
FI644_RS15580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FI644_RS15585	COG0825	malonyl-CoA metabolic process
FI644_RS15590	COG0205	6-phosphofructokinase activity
FI644_RS15600	COG3030	protein affecting phage T7 exclusion by the F plasmid
FI644_RS15605	COG0628	permease
FI644_RS15610	COG0372	Belongs to the citrate synthase family
FI644_RS15615	COG0538	isocitrate dehydrogenase activity
FI644_RS15620	COG0039	L-malate dehydrogenase activity
FI644_RS15630	COG0745	RESPONSE REGULATOR receiver
FI644_RS15635	COG5002	protein histidine kinase activity
FI644_RS15640	COG0330	HflC and HflK could
FI644_RS15645	COG0330	HflC and HflK could
FI644_RS15650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FI644_RS15650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FI644_RS15655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FI644_RS15660	COG1971	Probably functions as a manganese efflux pump
FI644_RS15665	COG0237	dephospho-CoA kinase activity
FI644_RS15670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FI644_RS15675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FI644_RS15680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FI644_RS15685	COG3611	Membrane attachment protein
FI644_RS15690	COG1484	DNA-dependent DNA replication
FI644_RS15700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FI644_RS15705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FI644_RS15715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FI644_RS15740	COG1725	Transcriptional regulator
FI644_RS15785	COG1363	Peptidase, m42
FI644_RS15795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FI644_RS15800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FI644_RS15805	COG0072	phenylalanine-tRNA ligase activity
FI644_RS15805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FI644_RS15810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FI644_RS15825	COG0437	4 iron, 4 sulfur cluster binding
FI644_RS15830	COG0243	molybdopterin cofactor binding
FI644_RS15845	COG2508	Transcriptional regulator
FI644_RS15845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FI644_RS15850	COG0243	molybdopterin cofactor binding
FI644_RS15855	COG0437	4 iron, 4 sulfur cluster binding
FI644_RS15865	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FI644_RS15870	COG1286	toxin biosynthetic process
FI644_RS15875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FI644_RS15875	COG1796	DNA polymerase
FI644_RS15885	COG3766	membrane
FI644_RS15890	COG0318	PFAM AMP-dependent synthetase and ligase
FI644_RS15895	COG1309	transcriptional regulator
FI644_RS15900	COG1024	Enoyl-CoA hydratase
FI644_RS15905	COG2086	electron transfer activity
FI644_RS15910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FI644_RS15915	COG3118	belongs to the thioredoxin family
FI644_RS15920	COG0322	excinuclease ABC activity
FI644_RS15930	COG1719	4-vinyl reductase, 4VR
FI644_RS15935	COG2009	succinate dehydrogenase
FI644_RS15940	COG1053	succinate dehydrogenase
FI644_RS15945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FI644_RS15950	COG0824	Thioesterase
FI644_RS15955	COG2197	response regulator
FI644_RS15960	COG1846	Transcriptional regulator
FI644_RS15970	COG0514	ATP-dependent DNA helicase (RecQ)
FI644_RS15975	COG5401	PFAM Sporulation and spore germination
FI644_RS15990	COG0622	Phosphoesterase
FI644_RS16000	COG0028	Belongs to the TPP enzyme family
FI644_RS16005	COG0440	acetolactate synthase activity
FI644_RS16015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FI644_RS16020	COG0473	3-isopropylmalate dehydrogenase activity
FI644_RS16025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FI644_RS16030	COG0066	3-isopropylmalate dehydratase activity
FI644_RS16035	COG1477	protein flavinylation
FI644_RS16035	COG0457	Tetratricopeptide repeat
FI644_RS16040	COG0544	peptidyl-prolyl cis-trans isomerase activity
FI644_RS16045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FI644_RS16050	COG1067	ATP-dependent peptidase activity
FI644_RS16050	COG0470	DNA polymerase III
FI644_RS16055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FI644_RS16060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FI644_RS16065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI644_RS16070	COG0765	amino acid transport
FI644_RS16090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FI644_RS16105	COG0113	porphobilinogen synthase activity
FI644_RS16110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FI644_RS16115	COG1388	LysM domain
FI644_RS16120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FI644_RS16130	COG0525	valine-tRNA ligase activity
FI644_RS16135	COG0285	dihydrofolate synthase activity
FI644_RS16140	COG3706	GGDEF domain
FI644_RS16170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FI644_RS16180	COG1459	type II secretion system
FI644_RS16190	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FI644_RS16220	COG2003	Belongs to the UPF0758 family
FI644_RS16225	COG1077	Cell shape determining protein MreB Mrl
FI644_RS16230	COG1792	Involved in formation and maintenance of cell shape
FI644_RS16240	COG0850	regulation of cytokinetic process
FI644_RS16245	COG2894	cell division
FI644_RS16250	COG0739	heme binding
FI644_RS16255	COG1994	Peptidase M50
FI644_RS16270	COG2868	ribosomal protein
FI644_RS16275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FI644_RS16280	COG3290	protein histidine kinase activity
FI644_RS16285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FI644_RS16290	COG4492	Belongs to the UPF0735 family
FI644_RS16295	COG0077	Prephenate dehydratase
FI644_RS16300	COG1827	regulation of RNA biosynthetic process
FI644_RS16310	COG1388	LysM domain
FI644_RS16335	COG0632	four-way junction helicase activity
FI644_RS16345	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FI644_RS16355	COG1862	Preprotein translocase
FI644_RS16365	COG2323	membrane
FI644_RS16370	COG2244	polysaccharide biosynthetic process
FI644_RS16380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FI644_RS16380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FI644_RS16385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FI644_RS16390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FI644_RS16390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FI644_RS16395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FI644_RS16400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FI644_RS16405	COG1490	D-aminoacyl-tRNA deacylase activity
FI644_RS16410	COG0860	N-Acetylmuramoyl-L-alanine amidase
FI644_RS16415	COG0124	histidyl-tRNA synthetase
FI644_RS16420	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FI644_RS16435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FI644_RS16445	COG1725	Transcriptional regulator
FI644_RS16450	COG1131	(ABC) transporter
FI644_RS16455	COG1131	(ABC) transporter
FI644_RS16460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FI644_RS16465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FI644_RS16470	COG2364	Membrane
FI644_RS16475	COG1959	2 iron, 2 sulfur cluster binding
FI644_RS16480	COG1104	cysteine desulfurase activity
FI644_RS16495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FI644_RS16515	COG0628	permease
FI644_RS16525	COG4472	Bacterial protein of unknown function (DUF965)
FI644_RS16535	COG3906	Belongs to the UPF0473 family
FI644_RS16540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FI644_RS16545	COG4122	O-methyltransferase activity
FI644_RS16550	COG0826	peptidase U32
FI644_RS16555	COG0826	peptidase U32
FI644_RS16560	COG0572	uridine kinase
FI644_RS16565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FI644_RS16570	COG0768	penicillin binding
FI644_RS16590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS16595	COG2226	methyltransferase
FI644_RS16600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FI644_RS16605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FI644_RS16610	COG0626	cystathionine gamma-synthase activity
FI644_RS16625	COG2329	Antibiotic biosynthesis monooxygenase
FI644_RS16640	COG1183	phosphatidylcholine synthase activity
FI644_RS16645	COG0688	phosphatidylethanolamine metabolic process
FI644_RS16655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FI644_RS16660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FI644_RS16670	COG1534	Rna-binding protein
FI644_RS16675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FI644_RS16680	COG1713	HD superfamily hydrolase involved in NAD metabolism
FI644_RS16685	COG0799	negative regulation of ribosome biogenesis
FI644_RS16690	COG2226	methyltransferase
FI644_RS16695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FI644_RS16700	COG1596	polysaccharide export
FI644_RS16700	COG1555	photosystem II stabilization
FI644_RS16705	COG2131	deaminase
FI644_RS16710	COG2333	competence protein COMEC
FI644_RS16710	COG0658	competence protein
FI644_RS16720	COG1466	dna polymerase III delta subunit
FI644_RS16735	COG0860	N-Acetylmuramoyl-L-alanine amidase
FI644_RS16745	COG0481	GTPase activity
FI644_RS16750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FI644_RS16755	COG1420	regulation of RNA biosynthetic process
FI644_RS16760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FI644_RS16765	COG0443	Heat shock 70 kDa protein
FI644_RS16775	COG2264	protein methyltransferase activity
FI644_RS16780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FI644_RS16785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FI644_RS16790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FI644_RS16795	COG1283	sodium-dependent phosphate transmembrane transporter activity
FI644_RS16805	COG1610	YqeY-like protein
FI644_RS16815	COG4864	UPF0365 protein
FI644_RS16835	COG1702	phosphate starvation-inducible protein PhoH
FI644_RS16840	COG1480	7TM receptor with intracellular HD hydrolase
FI644_RS16850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FI644_RS16855	COG0295	cytidine deaminase activity
FI644_RS16860	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FI644_RS16870	COG1381	Involved in DNA repair and RecF pathway recombination
FI644_RS16880	COG0751	glycine-tRNA ligase activity
FI644_RS16885	COG0517	IMP dehydrogenase activity
FI644_RS16890	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FI644_RS16900	COG0358	DNA primase activity
FI644_RS16905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FI644_RS16915	COG1960	acyl-CoA dehydrogenase activity
FI644_RS16925	COG2384	SAM-dependent methyltransferase
FI644_RS16930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FI644_RS16935	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FI644_RS16945	COG0513	Belongs to the DEAD box helicase family
FI644_RS16950	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FI644_RS16960	COG1121	(ABC) transporter
FI644_RS16965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FI644_RS16970	COG0735	belongs to the Fur family
FI644_RS16975	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FI644_RS16980	COG4709	membrane
FI644_RS16990	COG1388	LysM domain
FI644_RS16995	COG0840	transmembrane signaling receptor activity
FI644_RS17000	COG5521	maltodextrose utilization protein MalA
FI644_RS17005	COG1283	sodium-dependent phosphate transmembrane transporter activity
FI644_RS17010	COG2839	Protein conserved in bacteria
FI644_RS17015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI644_RS17025	COG0477	Major facilitator Superfamily
FI644_RS17030	COG0768	penicillin binding
FI644_RS17035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FI644_RS17040	COG0573	inorganic phosphate transmembrane transporter activity
FI644_RS17045	COG0581	inorganic phosphate transmembrane transporter activity
FI644_RS17055	COG0704	Plays a role in the regulation of phosphate uptake
FI644_RS17085	COG0768	penicillin binding
FI644_RS17105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FI644_RS17120	COG0457	Tetratricopeptide repeat
FI644_RS17120	COG0705	Rhomboid family
FI644_RS17125	COG0697	spore germination
FI644_RS17130	COG4483	Protein conserved in bacteria
FI644_RS17135	COG1368	sulfuric ester hydrolase activity
FI644_RS17150	COG0011	TIGRFAM Protein of
FI644_RS17160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI644_RS17180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FI644_RS17190	COG4537	Required for transformation and DNA binding
FI644_RS17195	COG4970	Tfp pilus assembly protein FimT
FI644_RS17230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FI644_RS17235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FI644_RS17240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FI644_RS17245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FI644_RS17250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FI644_RS17255	COG0095	Lipoate-protein ligase
FI644_RS17260	COG1131	(ABC) transporter
FI644_RS17265	COG0842	Transport permease protein
FI644_RS17270	COG4585	Histidine kinase
FI644_RS17275	COG2197	response regulator
FI644_RS17285	COG4176	ABC-type proline glycine betaine transport system permease component
FI644_RS17290	COG0517	IMP dehydrogenase activity
FI644_RS17290	COG4175	Glycine betaine
FI644_RS17295	COG1510	regulation of RNA biosynthetic process
FI644_RS17300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FI644_RS17305	COG1752	Esterase of the alpha-beta hydrolase superfamily
FI644_RS17320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FI644_RS17325	COG0006	proline dipeptidase activity
FI644_RS17330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FI644_RS17350	COG3854	ATPases associated with a variety of cellular activities
FI644_RS17390	COG3290	protein histidine kinase activity
FI644_RS17390	COG0840	transmembrane signaling receptor activity
FI644_RS17395	COG0511	ligase activity, forming carbon-carbon bonds
FI644_RS17400	COG0439	Biotin carboxylase
FI644_RS17405	COG1302	Protein conserved in bacteria
FI644_RS17410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FI644_RS17415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FI644_RS17420	COG1570	exodeoxyribonuclease VII activity
FI644_RS17425	COG1722	exodeoxyribonuclease VII activity
FI644_RS17435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FI644_RS17440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FI644_RS17445	COG1438	arginine binding
FI644_RS17450	COG0497	DNA recombination
FI644_RS17455	COG0750	zinc metalloprotease
FI644_RS17465	COG3093	addiction module antidote protein HigA
FI644_RS17470	COG0584	glycerophosphoryl diester phosphodiesterase
FI644_RS17480	COG3290	protein histidine kinase activity
FI644_RS17480	COG3829	transcription factor binding
FI644_RS17485	COG0280	phosphate acetyltransferase
FI644_RS17500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FI644_RS17505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FI644_RS17510	COG0022	dehydrogenase e1 component
FI644_RS17515	COG0508	dehydrogenase complex catalyzes the overall conversion of
FI644_RS17525	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FI644_RS17525	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FI644_RS17530	COG1703	isobutyryl-CoA mutase activity
FI644_RS17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI644_RS17545	COG0765	amino acid transport
FI644_RS17550	COG1126	abc transporter atp-binding protein
FI644_RS17555	COG4129	membrane
FI644_RS17560	COG1376	ErfK ybiS ycfS ynhG family protein
FI644_RS17565	COG0346	lactoylglutathione lyase activity
FI644_RS17570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FI644_RS17575	COG2195	Cleaves the N-terminal amino acid of tripeptides
FI644_RS17585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FI644_RS17590	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FI644_RS17625	COG2304	oxidoreductase activity
FI644_RS17655	COG2304	oxidoreductase activity
FI644_RS17665	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FI644_RS17670	COG1234	tRNA 3'-trailer cleavage
FI644_RS17675	COG0733	neurotransmitter:sodium symporter activity
FI644_RS17680	COG1902	pentaerythritol trinitrate reductase activity
FI644_RS17685	COG0463	Glycosyl transferase, family 2
FI644_RS17695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FI644_RS17700	COG1316	TRANSCRIPTIONal
FI644_RS17705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI644_RS17710	COG0300	oxidoreductase activity
FI644_RS17720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FI644_RS17745	COG4175	Glycine betaine
FI644_RS17745	COG0517	IMP dehydrogenase activity
FI644_RS17755	COG1073	alpha beta
FI644_RS17760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FI644_RS17770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FI644_RS17775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI644_RS17790	COG0667	Aldo Keto reductase
FI644_RS17805	COG1379	DNA repair
FI644_RS17810	COG1300	Membrane
FI644_RS17815	COG0735	belongs to the Fur family
FI644_RS17825	COG4974	Belongs to the 'phage' integrase family
FI644_RS17830	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FI644_RS17845	COG1686	Belongs to the peptidase S11 family
FI644_RS17855	COG2172	sigma factor antagonist activity
FI644_RS17880	COG0697	spore germination
FI644_RS17895	COG1547	Domain of unknown function (DUF309)
FI644_RS17905	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FI644_RS17910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FI644_RS17920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FI644_RS17925	COG1686	Belongs to the peptidase S11 family
FI644_RS17930	COG2715	membrane protein required for spore maturation
FI644_RS17935	COG0700	Nucleoside recognition
FI644_RS17940	COG1187	pseudouridine synthase activity
FI644_RS17945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS17950	COG1333	cytochrome c biogenesis protein
FI644_RS17955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FI644_RS17960	COG0745	RESPONSE REGULATOR receiver
FI644_RS17965	COG5002	protein histidine kinase activity
FI644_RS17970	COG1595	DNA-templated transcription, initiation
FI644_RS17985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FI644_RS17990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FI644_RS17995	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FI644_RS18005	COG4955	Helix-turn-helix domain
FI644_RS18010	COG0514	ATP-dependent DNA helicase (RecQ)
FI644_RS18015	COG1266	CAAX protease self-immunity
FI644_RS18030	COG3546	catalase activity
FI644_RS18050	COG1408	metallophosphoesterase
FI644_RS18055	COG4862	establishment of competence for transformation
FI644_RS18060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FI644_RS18065	COG0492	ferredoxin-NADP+ reductase activity
FI644_RS18070	COG0252	asparaginase activity
FI644_RS18075	COG2339	peptidase activity
FI644_RS18080	COG3409	Peptidoglycan-binding domain 1 protein
FI644_RS18080	COG3773	Cell wall hydrolase
FI644_RS18085	COG2959	enzyme of heme biosynthesis
FI644_RS18100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FI644_RS18110	COG0539	negative regulation of cytoplasmic translation
FI644_RS18115	COG1304	FMN binding
FI644_RS18140	COG1160	GTP binding
FI644_RS18145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FI644_RS18160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FI644_RS18165	COG0776	regulation of translation
FI644_RS18170	COG0302	gtp cyclohydrolase
FI644_RS18180	COG0142	geranyltranstransferase activity
FI644_RS18185	COG2226	methyltransferase
FI644_RS18190	COG0142	geranyltranstransferase activity
FI644_RS18195	COG0105	UTP biosynthetic process
FI644_RS18200	COG4585	Histidine kinase
FI644_RS18210	COG1131	(ABC) transporter
FI644_RS18215	COG1511	domain protein
FI644_RS18215	COG0842	Transport permease protein
FI644_RS18225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FI644_RS18230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FI644_RS18235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FI644_RS18240	COG4401	Chorismate mutase type I
FI644_RS18245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FI644_RS18250	COG0287	Prephenate dehydrogenase
FI644_RS18265	COG0457	Tetratricopeptide repeat
FI644_RS18285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FI644_RS18295	COG4347	Protein of unknown function (DUF1405)
FI644_RS18305	COG2738	Putative neutral zinc metallopeptidase
FI644_RS18310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FI644_RS18315	COG1694	Mazg nucleotide pyrophosphohydrolase
FI644_RS18320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FI644_RS18325	COG1803	Methylglyoxal synthase
FI644_RS18330	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FI644_RS18335	COG0438	transferase activity, transferring glycosyl groups
FI644_RS18350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FI644_RS18355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FI644_RS18360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FI644_RS18365	COG1199	ATP-dependent helicase activity
FI644_RS18365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FI644_RS18390	COG3935	DnaD domain protein
FI644_RS18395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FI644_RS18405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FI644_RS18405	COG4499	WXG100 protein secretion system (Wss), protein YukC
FI644_RS18410	COG3331	DNA recombination
FI644_RS18440	COG0601	transmembrane transport
FI644_RS18450	COG0071	Belongs to the small heat shock protein (HSP20) family
FI644_RS18455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI644_RS18460	COG1111	helicase
FI644_RS18460	COG1205	dead DEAH box helicase
FI644_RS18465	COG3359	exonuclease
FI644_RS18475	COG4474	Belongs to the UPF0398 family
FI644_RS18480	COG3599	regulation of cell shape
FI644_RS18505	COG1199	ATP-dependent helicase activity
FI644_RS18510	COG2151	metal-sulfur cluster biosynthetic enzyme
FI644_RS18545	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FI644_RS18555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FI644_RS18560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FI644_RS18575	COG2233	PERMEase
FI644_RS18585	COG3424	synthase
FI644_RS18590	COG1755	Isoprenylcysteine carboxyl methyltransferase
FI644_RS18595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FI644_RS18610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FI644_RS18635	COG0328	RNA-DNA hybrid ribonuclease activity
FI644_RS18640	COG0328	RNA-DNA hybrid ribonuclease activity
FI644_RS18650	COG1278	Cold shock
FI644_RS18660	COG0400	carboxylic ester hydrolase activity
FI644_RS18665	COG0655	NAD(P)H dehydrogenase (quinone) activity
FI644_RS18670	COG0803	Belongs to the bacterial solute-binding protein 9 family
FI644_RS18675	COG1121	(ABC) transporter
FI644_RS18680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FI644_RS18680	COG1321	iron dependent repressor
FI644_RS18685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FI644_RS18690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FI644_RS18695	COG1321	iron dependent repressor
FI644_RS18705	COG2226	methyltransferase
FI644_RS18715	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FI644_RS18745	COG1418	mRNA catabolic process
FI644_RS18750	COG0488	(ABC) transporter
FI644_RS18755	COG1413	lyase activity
FI644_RS18760	COG0129	dihydroxy-acid dehydratase activity
FI644_RS18770	COG2136	Putative SAM-dependent methyltransferase
FI644_RS18770	COG2521	methyltransferase
FI644_RS18780	COG2310	stress, protein
FI644_RS18785	COG0861	Integral membrane protein TerC family
FI644_RS18820	COG3853	Toxic anion resistance protein (TelA)
FI644_RS18825	COG2310	stress, protein
FI644_RS18840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FI644_RS18845	COG0204	Acyl-transferase
FI644_RS18855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FI644_RS18860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FI644_RS18865	COG0805	protein transport
FI644_RS18880	COG5002	protein histidine kinase activity
FI644_RS18895	COG2755	lipolytic protein G-D-S-L family
FI644_RS18900	COG4698	Protein conserved in bacteria
FI644_RS18920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FI644_RS18925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FI644_RS18930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI644_RS18935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FI644_RS18940	COG0456	acetyltransferase
FI644_RS18945	COG3829	transcription factor binding
FI644_RS18955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI644_RS18960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FI644_RS18990	COG1429	ligase activity, forming nitrogen-metal bonds
FI644_RS18995	COG1429	ligase activity, forming nitrogen-metal bonds
FI644_RS19000	COG1509	lysine 2,3-aminomutase activity
FI644_RS19020	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FI644_RS19030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FI644_RS19030	COG3711	transcriptional antiterminator
FI644_RS19040	COG3414	Phosphotransferase system galactitol-specific IIB component
FI644_RS19045	COG3775	system Galactitol-specific IIC component
FI644_RS19050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FI644_RS19055	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS19060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FI644_RS19065	COG4479	Belongs to the UPF0346 family
FI644_RS19080	COG4326	sporulation control protein
FI644_RS19085	COG0584	glycerophosphoryl diester phosphodiesterase
FI644_RS19100	COG1876	peptidase activity
FI644_RS19105	COG0793	Belongs to the peptidase S41A family
FI644_RS19105	COG3409	Peptidoglycan-binding domain 1 protein
FI644_RS19115	COG0523	cobalamin synthesis protein
FI644_RS19140	COG0745	RESPONSE REGULATOR receiver
FI644_RS19145	COG3850	Histidine kinase
FI644_RS19145	COG5002	protein histidine kinase activity
FI644_RS19155	COG2340	Cysteine-rich secretory protein family
FI644_RS19165	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS19185	COG0804	urea catabolic process
FI644_RS19190	COG0586	Pfam SNARE associated Golgi protein
FI644_RS19210	COG1131	(ABC) transporter
FI644_RS19215	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FI644_RS19220	COG4667	esterase of the alpha-beta hydrolase superfamily
FI644_RS19235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS19240	COG2217	Heavy metal translocating P-type atpase
FI644_RS19250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FI644_RS19250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FI644_RS19255	COG0307	riboflavin synthase, alpha
FI644_RS19260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FI644_RS19260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FI644_RS19265	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FI644_RS19270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FI644_RS19275	COG1793	dna ligase
FI644_RS19275	COG3285	dna ligase
FI644_RS19280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FI644_RS19285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FI644_RS19290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FI644_RS19295	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FI644_RS19300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FI644_RS19305	COG3541	Predicted nucleotidyltransferase
FI644_RS19325	COG0513	Belongs to the DEAD box helicase family
FI644_RS19355	COG1113	amino acid transport
FI644_RS19360	COG1280	lysine exporter protein (LysE YggA)
FI644_RS19370	COG3850	Histidine kinase
FI644_RS19370	COG5002	protein histidine kinase activity
FI644_RS19380	COG0398	Pfam SNARE associated Golgi protein
FI644_RS19385	COG4166	transmembrane transport
FI644_RS19400	COG3852	Histidine kinase
FI644_RS19410	COG0840	transmembrane signaling receptor activity
FI644_RS19415	COG1366	Belongs to the anti-sigma-factor antagonist family
FI644_RS19420	COG0070	glutamate synthase
FI644_RS19420	COG0069	glutamate synthase activity
FI644_RS19420	COG0067	glutamate synthase
FI644_RS19425	COG0493	'glutamate synthase
FI644_RS19430	COG0004	ammonium transporteR
FI644_RS19435	COG1280	lysine exporter protein (LysE YggA)
FI644_RS19440	COG0656	L-ascorbic acid biosynthetic process
FI644_RS19455	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FI644_RS19465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI644_RS19470	COG2223	nitrite transmembrane transporter activity
FI644_RS19480	COG0217	transcriptional regulatory protein
FI644_RS19485	COG5577	PFAM Coat F domain
FI644_RS19490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FI644_RS19515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FI644_RS19525	COG0463	Glycosyl transferase, family 2
FI644_RS19535	COG0716	FMN binding
FI644_RS19540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FI644_RS19545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FI644_RS19550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI644_RS19560	COG0840	transmembrane signaling receptor activity
FI644_RS19565	COG1328	CTP reductase activity
FI644_RS19580	COG0490	domain, Protein
FI644_RS19580	COG0471	metal ion transport
FI644_RS19615	COG5609	conserved protein (DUF2294)
FI644_RS19620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FI644_RS19625	COG4294	response to UV
FI644_RS19635	COG4294	response to UV
FI644_RS19640	COG3871	stress protein (general stress protein 26)
FI644_RS19645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FI644_RS19655	COG1533	DNA photolyase activity
FI644_RS19675	COG2155	Conserved Protein
FI644_RS19690	COG1660	Displays ATPase and GTPase activities
FI644_RS19695	COG0726	polysaccharide deacetylase
FI644_RS19705	COG2814	Major facilitator Superfamily
FI644_RS19710	COG2258	MOSC domain
FI644_RS19720	COG0512	Glutamine amidotransferase of anthranilate synthase
FI644_RS19720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FI644_RS19730	COG0134	indole-3-glycerol-phosphate synthase activity
FI644_RS19775	COG0243	molybdopterin cofactor binding
FI644_RS19805	COG2223	nitrite transmembrane transporter activity
FI644_RS19815	COG2197	response regulator
FI644_RS19830	COG2966	Psort location CytoplasmicMembrane, score
FI644_RS19840	COG1132	(ABC) transporter
FI644_RS19865	COG1686	Belongs to the peptidase S11 family
FI644_RS19895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FI644_RS19900	COG1054	Belongs to the UPF0176 family
FI644_RS19940	COG0662	Cupin 2, conserved barrel domain protein
FI644_RS19955	COG2323	membrane
FI644_RS19965	COG3883	PFAM NLP P60 protein
FI644_RS19965	COG0791	NLP P60 protein
FI644_RS19970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FI644_RS19975	COG1414	Transcriptional regulator
FI644_RS19980	COG0584	glycerophosphoryl diester phosphodiesterase
FI644_RS19985	COG3842	ATPase activity
FI644_RS20010	COG1725	Transcriptional regulator
FI644_RS20015	COG1131	(ABC) transporter
FI644_RS20025	COG1595	DNA-templated transcription, initiation
FI644_RS20035	COG5002	protein histidine kinase activity
FI644_RS20035	COG3850	Histidine kinase
FI644_RS20040	COG1136	(ABC) transporter
FI644_RS20045	COG1136	(ABC) transporter
FI644_RS20045	COG0577	efflux transmembrane transporter activity
FI644_RS20050	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS20085	COG1595	DNA-templated transcription, initiation
FI644_RS20095	COG0477	Major facilitator Superfamily
FI644_RS20110	COG1595	DNA-templated transcription, initiation
FI644_RS20160	COG3708	Transcriptional regulator
FI644_RS20160	COG2207	Transcriptional regulator
FI644_RS20175	COG1960	acyl-CoA dehydrogenase activity
FI644_RS20180	COG0183	Belongs to the thiolase family
FI644_RS20190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FI644_RS20195	COG1183	phosphatidylcholine synthase activity
FI644_RS20200	COG0322	excinuclease ABC activity
FI644_RS20210	COG1022	Amp-dependent synthetase and ligase
FI644_RS20225	COG0683	leucine binding
FI644_RS20240	COG5001	Diguanylate cyclase
FI644_RS20240	COG3300	MHYT domain
FI644_RS20245	COG0243	molybdopterin cofactor binding
FI644_RS20250	COG0534	Mate efflux family protein
FI644_RS20255	COG3706	GGDEF domain
FI644_RS20265	COG0431	NADPH-dependent FMN reductase
FI644_RS20270	COG0861	Integral membrane protein TerC family
FI644_RS20280	COG1187	pseudouridine synthase activity
FI644_RS20285	COG2116	formate transmembrane transporter activity
FI644_RS20310	COG3973	AAA domain
FI644_RS20315	COG1017	nitric oxide dioxygenase activity
FI644_RS20315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FI644_RS20325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI644_RS20330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI644_RS20335	COG1309	transcriptional regulator
FI644_RS20340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FI644_RS20395	COG2824	Alkylphosphonate utilization operon protein PhnA
FI644_RS20410	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FI644_RS20415	COG1268	BioY protein
FI644_RS20420	COG0840	transmembrane signaling receptor activity
FI644_RS20435	COG1129	ABC transporter
FI644_RS20440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FI644_RS20450	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FI644_RS20455	COG1349	DNA-binding transcription factor activity
FI644_RS20460	COG0235	Class ii aldolase
FI644_RS20465	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS20495	COG4869	propanediol catabolic process
FI644_RS20500	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FI644_RS20505	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI644_RS20515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI644_RS20520	COG0456	acetyltransferase
FI644_RS20525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FI644_RS20560	COG1051	belongs to the nudix hydrolase family
FI644_RS20560	COG1056	cytidyltransferase-related domain
FI644_RS20575	COG1397	ADP-ribosylglycohydrolase
FI644_RS20595	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS20600	COG3069	C4-dicarboxylate transmembrane transporter activity
FI644_RS20615	COG0668	transmembrane transport
FI644_RS20620	COG1253	flavin adenine dinucleotide binding
FI644_RS20630	COG0598	Magnesium transport protein CorA
FI644_RS20640	COG1366	Belongs to the anti-sigma-factor antagonist family
FI644_RS20645	COG2172	sigma factor antagonist activity
FI644_RS20650	COG1191	sigma factor activity
FI644_RS20675	COG1113	amino acid transport
FI644_RS20685	COG1396	sequence-specific DNA binding
FI644_RS20695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS20705	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS20710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FI644_RS20710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FI644_RS20715	COG1522	sequence-specific DNA binding
FI644_RS20720	COG0436	Aminotransferase
FI644_RS20725	COG0577	efflux transmembrane transporter activity
FI644_RS20730	COG1136	(ABC) transporter
FI644_RS20735	COG2205	protein histidine kinase activity
FI644_RS20740	COG0745	RESPONSE REGULATOR receiver
FI644_RS20745	COG0346	lactoylglutathione lyase activity
FI644_RS20750	COG2357	RelA SpoT domain protein
FI644_RS20760	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS20765	COG0326	Molecular chaperone. Has ATPase activity
FI644_RS20775	COG0385	Bile acid
FI644_RS20780	COG0697	spore germination
FI644_RS20790	COG1193	negative regulation of DNA recombination
FI644_RS20820	COG2814	Major facilitator Superfamily
FI644_RS20825	COG0697	spore germination
FI644_RS20830	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS20870	COG4555	ABC transporter
FI644_RS20895	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FI644_RS20905	COG1309	transcriptional regulator
FI644_RS20935	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FI644_RS20940	COG1140	nitrate reductase beta subunit
FI644_RS20950	COG2181	nitrate reductase activity
FI644_RS20955	COG2223	nitrite transmembrane transporter activity
FI644_RS20960	COG3773	Cell wall hydrolase
FI644_RS20965	COG1764	response to oxidative stress
FI644_RS20970	COG0708	Exodeoxyribonuclease III
FI644_RS20980	COG1131	(ABC) transporter
FI644_RS20990	COG1473	amidohydrolase
FI644_RS21000	COG4948	Mandelate Racemase Muconate Lactonizing
FI644_RS21010	COG1280	lysine exporter protein (LysE YggA)
FI644_RS21015	COG2814	Major facilitator Superfamily
FI644_RS21050	COG0601	transmembrane transport
FI644_RS21055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI644_RS21090	COG0492	ferredoxin-NADP+ reductase activity
FI644_RS21125	COG2814	Major facilitator Superfamily
FI644_RS21140	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FI644_RS21165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FI644_RS21175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FI644_RS21180	COG0110	maltose O-acetyltransferase activity
FI644_RS21200	COG0596	Alpha beta hydrolase
FI644_RS21205	COG1309	transcriptional regulator
FI644_RS21225	COG0697	spore germination
FI644_RS21265	COG0584	glycerophosphoryl diester phosphodiesterase
FI644_RS21275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FI644_RS21280	COG2329	Antibiotic biosynthesis monooxygenase
FI644_RS21285	COG0640	Transcriptional regulator
FI644_RS21290	COG0346	lactoylglutathione lyase activity
FI644_RS21295	COG1794	racemase activity, acting on amino acids and derivatives
FI644_RS21315	COG3655	Transcriptional regulator
FI644_RS21320	COG3739	integral membrane protein
FI644_RS21345	COG1595	DNA-templated transcription, initiation
FI644_RS21380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FI644_RS21385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FI644_RS21390	COG0778	Nitroreductase
FI644_RS21395	COG0346	lactoylglutathione lyase activity
FI644_RS21400	COG2153	protein acetylation
FI644_RS21410	COG2807	transmembrane transport
FI644_RS21415	COG0124	histidyl-tRNA synthetase
FI644_RS21425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI644_RS21430	COG1959	2 iron, 2 sulfur cluster binding
FI644_RS21450	COG0018	arginyl-trna synthetase
FI644_RS21455	COG2211	Major facilitator Superfamily
FI644_RS21460	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS21470	COG3832	glyoxalase III activity
FI644_RS21485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FI644_RS21490	COG2404	hydrolase activity, acting on ester bonds
FI644_RS21505	COG0529	Catalyzes the synthesis of activated sulfate
FI644_RS21525	COG2814	Major facilitator Superfamily
FI644_RS21535	COG1595	DNA-templated transcription, initiation
FI644_RS21545	COG3973	AAA domain
FI644_RS21550	COG3848	Pyruvate phosphate dikinase
FI644_RS21550	COG0574	Belongs to the PEP-utilizing enzyme family
FI644_RS21560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FI644_RS21585	COG1131	(ABC) transporter
FI644_RS21605	COG0390	transport system, permease component
FI644_RS21610	COG2207	Transcriptional regulator
FI644_RS21610	COG3708	Transcriptional regulator
FI644_RS21620	COG3706	GGDEF domain
FI644_RS21650	COG1294	oxidase, subunit
FI644_RS21655	COG1271	oxidase subunit
FI644_RS21665	COG0494	nUDIX hydrolase
FI644_RS21680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FI644_RS21685	COG1301	dicarboxylic acid transport
FI644_RS21695	COG2244	polysaccharide biosynthetic process
FI644_RS21700	COG2076	Multidrug Resistance protein
FI644_RS21705	COG2076	Multidrug Resistance protein
FI644_RS21710	COG0840	transmembrane signaling receptor activity
FI644_RS21710	COG5278	phosphoserine phosphatase activity
FI644_RS21740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FI644_RS21745	COG0778	Nitroreductase
FI644_RS21755	COG4895	conserved protein (DUF2196)
FI644_RS21770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FI644_RS21780	COG1695	Transcriptional regulator
FI644_RS21805	COG1595	DNA-templated transcription, initiation
FI644_RS21820	COG0628	permease
FI644_RS21830	COG3842	ATPase activity
FI644_RS21835	COG1176	ABC-type spermidine putrescine transport system, permease component I
FI644_RS21840	COG1177	transmembrane transport
FI644_RS21845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FI644_RS21850	COG2861	carbohydrate metabolic process
FI644_RS21855	COG4948	Mandelate Racemase Muconate Lactonizing
FI644_RS21860	COG2205	protein histidine kinase activity
FI644_RS21865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FI644_RS21875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FI644_RS21880	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FI644_RS21890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FI644_RS21910	COG2346	COG2346, Truncated hemoglobins
FI644_RS21925	COG0646	methionine synthase
FI644_RS21925	COG1410	methionine synthase
FI644_RS21930	COG0646	methionine synthase
FI644_RS21930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FI644_RS21935	COG0626	cystathionine gamma-synthase activity
FI644_RS21940	COG0626	cystathionine gamma-synthase activity
FI644_RS21945	COG0567	Dehydrogenase, E1 component
FI644_RS21950	COG0508	dehydrogenase complex catalyzes the overall conversion of
FI644_RS21965	COG0318	PFAM AMP-dependent synthetase and ligase
FI644_RS21990	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FI644_RS22010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FI644_RS22010	COG0392	lysyltransferase activity
FI644_RS22015	COG1268	BioY protein
FI644_RS22020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FI644_RS22040	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FI644_RS22050	COG2340	Cysteine-rich secretory protein family
FI644_RS22060	COG4149	molybdate abc transporter
FI644_RS22065	COG0725	ABC transporter, periplasmic molybdate-binding protein
FI644_RS22070	COG1910	domain protein
FI644_RS22085	COG0488	(ABC) transporter
FI644_RS22100	COG1999	signal sequence binding
FI644_RS22105	COG1012	belongs to the aldehyde dehydrogenase family
FI644_RS22110	COG0437	4 iron, 4 sulfur cluster binding
FI644_RS22115	COG0243	molybdopterin cofactor binding
FI644_RS22135	COG0348	domain, Protein
FI644_RS22145	COG2814	Major facilitator Superfamily
FI644_RS22165	COG5002	protein histidine kinase activity
FI644_RS22175	COG2310	stress, protein
FI644_RS22180	COG2310	stress, protein
FI644_RS22195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FI644_RS22205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FI644_RS22215	COG3663	DNA glycosylase
FI644_RS22230	COG2027	D-alanyl-D-alanine carboxypeptidase
FI644_RS22235	COG2353	YceI-like domain
FI644_RS22245	COG1063	alcohol dehydrogenase
FI644_RS22250	COG5577	PFAM Coat F domain
FI644_RS22265	COG4086	secreted protein
FI644_RS22275	COG3239	Fatty acid desaturase
FI644_RS22280	COG4585	Histidine kinase
FI644_RS22285	COG2197	response regulator
FI644_RS22290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FI644_RS22295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FI644_RS22300	COG1116	anion transmembrane transporter activity
FI644_RS22305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI644_RS22310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI644_RS22320	COG0352	thiamine-phosphate diphosphorylase activity
FI644_RS22320	COG0351	phosphomethylpyrimidine kinase
FI644_RS22325	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FI644_RS22340	COG2205	protein histidine kinase activity
FI644_RS22360	COG1657	PFAM Prenyltransferase squalene oxidase
FI644_RS22380	COG0714	Associated with various cellular activities
FI644_RS22410	COG1309	transcriptional regulator
FI644_RS22420	COG2318	DinB family
FI644_RS22455	COG1929	Belongs to the glycerate kinase type-1 family
FI644_RS22460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FI644_RS22470	COG1609	Transcriptional regulator
FI644_RS22475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FI644_RS22480	COG1869	D-ribose catabolic process
FI644_RS22485	COG1129	ABC transporter
FI644_RS22490	COG1172	Belongs to the binding-protein-dependent transport system permease family
FI644_RS22495	COG1879	ABC-type sugar transport system periplasmic component
FI644_RS22500	COG0194	GDP metabolic process
FI644_RS22520	COG0006	proline dipeptidase activity
FI644_RS22545	COG2124	cytochrome p450
FI644_RS22600	COG1725	Transcriptional regulator
FI644_RS22635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FI644_RS22640	COG0431	NADPH-dependent FMN reductase
FI644_RS22645	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FI644_RS22695	COG2226	methyltransferase
FI644_RS22705	COG2072	flavoprotein involved in K transport
FI644_RS22725	COG0640	Transcriptional regulator
FI644_RS22730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FI644_RS22735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FI644_RS22785	COG2207	Transcriptional regulator
FI644_RS22785	COG1917	Cupin 2, conserved barrel domain protein
FI644_RS22795	COG0251	oxidation-reduction process
FI644_RS22805	COG1473	amidohydrolase
FI644_RS22810	COG0076	glutamate decarboxylase activity
FI644_RS22815	COG1278	Cold shock
FI644_RS22840	COG0860	N-Acetylmuramoyl-L-alanine amidase
FI644_RS22845	COG1388	LysM domain
FI644_RS22865	COG1011	Hydrolase
FI644_RS22870	COG3773	Cell wall hydrolase
FI644_RS22875	COG0386	Belongs to the glutathione peroxidase family
FI644_RS22880	COG0745	RESPONSE REGULATOR receiver
FI644_RS22885	COG5002	protein histidine kinase activity
FI644_RS22895	COG0402	S-adenosylhomocysteine deaminase activity
FI644_RS22900	COG0402	S-adenosylhomocysteine deaminase activity
FI644_RS22910	COG0583	DNA-binding transcription factor activity
FI644_RS22925	COG1115	amino acid carrier protein
FI644_RS22930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FI644_RS22935	COG0187	DNA topoisomerase II activity
FI644_RS22940	COG1832	CoA-binding protein
FI644_RS22945	COG0402	S-adenosylhomocysteine deaminase activity
FI644_RS22955	COG3665	Urea carboxylase-associated protein
FI644_RS22960	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FI644_RS22965	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FI644_RS22970	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FI644_RS22985	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FI644_RS23005	COG0163	prenyltransferase activity
FI644_RS23010	COG1335	isochorismatase
FI644_RS23035	COG0746	molybdenum cofactor guanylyltransferase activity
FI644_RS23045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FI644_RS23050	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FI644_RS23050	COG3608	succinylglutamate desuccinylase aspartoacylase
FI644_RS23060	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FI644_RS23065	COG3858	chitin binding
FI644_RS23070	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FI644_RS23075	COG5002	protein histidine kinase activity
FI644_RS23080	COG2843	Capsule synthesis protein
FI644_RS23085	COG1522	sequence-specific DNA binding
FI644_RS23090	COG0504	CTP synthase activity
FI644_RS23100	COG3647	Membrane
FI644_RS23110	COG2048	Heterodisulfide reductase, subunit B
FI644_RS23115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FI644_RS23120	COG1053	succinate dehydrogenase
FI644_RS23125	COG1027	Aspartate ammonia-lyase
FI644_RS23130	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FI644_RS23135	COG4191	Histidine kinase
FI644_RS23140	COG0784	Response regulator, receiver
FI644_RS23175	COG4841	protein insertion into membrane
FI644_RS23185	COG0824	Thioesterase
FI644_RS23190	COG0464	growth
FI644_RS23210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS23215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FI644_RS23290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS23305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FI644_RS23315	COG0753	catalase activity
FI644_RS23320	COG0488	(ABC) transporter
FI644_RS23325	COG1307	EDD domain protein, DegV family
FI644_RS23335	COG0179	Fumarylacetoacetate (FAA) hydrolase
FI644_RS23340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI644_RS23345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FI644_RS23350	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FI644_RS23360	COG0508	dehydrogenase complex catalyzes the overall conversion of
FI644_RS23365	COG0022	dehydrogenase e1 component
FI644_RS23385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FI644_RS23390	COG4120	Belongs to the binding-protein-dependent transport system permease family
FI644_RS23405	COG3327	negative regulation of DNA-templated transcription, initiation
FI644_RS23410	COG0183	Belongs to the thiolase family
FI644_RS23415	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI644_RS23420	COG1024	Enoyl-CoA hydratase
FI644_RS23425	COG1024	Enoyl-CoA hydratase
FI644_RS23450	COG3396	Phenylacetate-CoA oxygenase
FI644_RS23455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FI644_RS23460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FI644_RS23470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FI644_RS23490	COG1760	l-serine dehydratase
FI644_RS23495	COG1760	l-serine dehydratase
FI644_RS23505	COG0586	Pfam SNARE associated Golgi protein
FI644_RS23510	COG0726	polysaccharide deacetylase
FI644_RS23520	COG0671	phosphoesterase, PA-phosphatase related
FI644_RS23565	COG4641	Protein conserved in bacteria
FI644_RS23575	COG0438	transferase activity, transferring glycosyl groups
FI644_RS23590	COG0438	transferase activity, transferring glycosyl groups
FI644_RS23605	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FI644_RS23605	COG0662	Cupin 2, conserved barrel domain protein
FI644_RS23610	COG1482	cell wall glycoprotein biosynthetic process
FI644_RS23625	COG0438	transferase activity, transferring glycosyl groups
FI644_RS23625	COG1216	Glycosyl transferase, family 2
FI644_RS23660	COG2089	acid synthase
FI644_RS23670	COG1181	Belongs to the D-alanine--D-alanine ligase family
FI644_RS23675	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FI644_RS23680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FI644_RS23685	COG1086	Polysaccharide biosynthesis protein
FI644_RS23690	COG0653	protein targeting
FI644_RS23700	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FI644_RS23705	COG1091	dTDP-4-dehydrorhamnose reductase activity
FI644_RS23710	COG1088	dTDP-glucose 4,6-dehydratase activity
FI644_RS23715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FI644_RS23720	COG1368	sulfuric ester hydrolase activity
FI644_RS23730	COG1363	Peptidase, m42
FI644_RS23745	COG5522	Integral membrane protein (intg_mem_TP0381)
FI644_RS23755	COG0419	ATPase involved in DNA repair
FI644_RS23790	COG0840	transmembrane signaling receptor activity
FI644_RS23790	COG3290	protein histidine kinase activity
FI644_RS23820	COG3813	Protein conserved in bacteria
FI644_RS23825	COG0840	transmembrane signaling receptor activity
FI644_RS23830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FI644_RS23835	COG1556	Lactate utilization protein
FI644_RS23840	COG1139	Iron-sulfur cluster binding protein
FI644_RS23845	COG0247	lactate metabolic process
FI644_RS23850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FI644_RS23860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FI644_RS23920	COG4846	Membrane protein involved in cytochrome C biogenesis
FI644_RS23925	COG2201	protein-glutamate methylesterase activity
FI644_RS23930	COG0785	Cytochrome C biogenesis protein
FI644_RS23940	COG1132	(ABC) transporter
FI644_RS23945	COG1132	(ABC) transporter
FI644_RS24035	COG3763	UPF0154 protein
FI644_RS24050	COG4224	UPF0291 protein
FI644_RS24055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FI644_RS24060	COG1388	LysM domain
FI644_RS24065	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FI644_RS24070	COG0174	glutamine synthetase
FI644_RS24075	COG0789	Transcriptional regulator
FI644_RS24080	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FI644_RS24085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FI644_RS24090	COG2860	membrane
FI644_RS24095	COG0464	growth
FI644_RS24115	COG1923	regulation of RNA biosynthetic process
FI644_RS24120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FI644_RS24125	COG1077	Cell shape determining protein MreB Mrl
FI644_RS24165	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FI644_RS24180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI644_RS24185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FI644_RS24190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FI644_RS24205	COG4974	Belongs to the 'phage' integrase family
FI644_RS24215	COG2258	MOSC domain
FI644_RS24220	COG0583	DNA-binding transcription factor activity
FI644_RS24240	COG0351	phosphomethylpyrimidine kinase
FI644_RS24245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FI644_RS24250	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FI644_RS24270	COG2807	transmembrane transport
FI644_RS24280	COG0546	phosphoglycolate phosphatase activity
FI644_RS24290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FI644_RS24325	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FI644_RS24330	COG2258	MOSC domain
FI644_RS24345	COG0688	phosphatidylethanolamine metabolic process
FI644_RS24360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FI644_RS24365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FI644_RS24370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FI644_RS24380	COG1280	lysine exporter protein (LysE YggA)
FI644_RS24405	COG4550	Control of competence regulator ComK, YlbF/YmcA
FI644_RS24410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FI644_RS24415	COG1013	pyruvate-flavodoxin oxidoreductase activity
FI644_RS24420	COG0674	pyruvate-flavodoxin oxidoreductase activity
FI644_RS24420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FI644_RS24430	COG2359	stage V sporulation protein S
FI644_RS24435	COG1692	metallophosphoesterase
FI644_RS24440	COG1418	mRNA catabolic process
FI644_RS24445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FI644_RS24450	COG1546	Belongs to the CinA family
FI644_RS24450	COG1058	Belongs to the CinA family
FI644_RS24455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FI644_RS24460	COG1426	Protein conserved in bacteria
FI644_RS24475	COG0300	oxidoreductase activity
FI644_RS24480	COG0612	Peptidase, M16
FI644_RS24485	COG0612	Peptidase, M16
FI644_RS24490	COG1114	Component of the transport system for branched-chain amino acids
FI644_RS24495	COG1079	Belongs to the binding-protein-dependent transport system permease family
FI644_RS24500	COG4603	Belongs to the binding-protein-dependent transport system permease family
FI644_RS24505	COG3845	ABC transporter
FI644_RS24510	COG1744	ABC transporter substrate-binding protein PnrA-like
FI644_RS24515	COG2188	Transcriptional regulator
FI644_RS24520	COG1674	ftsk spoiiie
FI644_RS24520	COG4980	gas vesicle protein
FI644_RS24530	COG0740	serine-type endopeptidase activity
FI644_RS24535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FI644_RS24545	COG0527	aspartate kinase activity
FI644_RS24550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FI644_RS24555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FI644_RS24560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FI644_RS24565	COG1873	PFAM PRC-barrel domain
FI644_RS24570	COG0612	Peptidase, M16
FI644_RS24575	COG0726	polysaccharide deacetylase
FI644_RS24580	COG1185	polyribonucleotide nucleotidyltransferase activity
FI644_RS24585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FI644_RS24590	COG0196	riboflavin kinase activity
FI644_RS24595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FI644_RS24605	COG1550	Protein conserved in bacteria
FI644_RS24610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FI644_RS24615	COG1358	cellular component organization or biogenesis
FI644_RS24620	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FI644_RS24625	COG0195	Participates in both transcription termination and antitermination
FI644_RS24630	COG0779	Required for maturation of 30S ribosomal subunits
FI644_RS24635	COG2176	DNA-directed DNA polymerase activity
FI644_RS24640	COG0442	prolyl-tRNA aminoacylation
FI644_RS24645	COG0750	zinc metalloprotease
FI644_RS24650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FI644_RS24655	COG4589	Belongs to the CDS family
FI644_RS24660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FI644_RS24665	COG0233	cytoplasmic translational termination
FI644_RS24670	COG0528	UMP kinase activity
FI644_RS24700	COG1191	sigma factor activity
FI644_RS24705	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FI644_RS24710	COG1776	CheC inhibitor of MCP methylation
FI644_RS24715	COG0835	chemotaxis
FI644_RS24720	COG0643	Histidine kinase
FI644_RS24720	COG2198	Histidine kinase
FI644_RS24725	COG2201	protein-glutamate methylesterase activity
FI644_RS24730	COG0455	bacterial-type flagellum organization
FI644_RS24735	COG1419	protein localization to endoplasmic reticulum
FI644_RS24740	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FI644_RS24745	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FI644_RS24750	COG1684	flagellar biosynthetic protein fliR
FI644_RS24755	COG1987	bacterial-type flagellum assembly
FI644_RS24760	COG1338	Plays a role in the flagellum-specific transport system
FI644_RS24765	COG3190	flagellar
FI644_RS24770	COG2201	protein-glutamate methylesterase activity
FI644_RS24775	COG1776	CheC inhibitor of MCP methylation
FI644_RS24775	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FI644_RS24780	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FI644_RS24785	COG1580	Controls the rotational direction of flagella during chemotaxis
FI644_RS24790	COG1582	Flagellar protein (FlbD)
FI644_RS24805	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FI644_RS24820	COG2882	bacterial-type flagellum organization
FI644_RS24825	COG1157	protein secretion by the type III secretion system
FI644_RS24830	COG1317	bacterial-type flagellum organization
FI644_RS24835	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FI644_RS24840	COG1766	The M ring may be actively involved in energy transduction
FI644_RS24845	COG1677	Flagellar hook-basal body complex protein FliE
FI644_RS24850	COG1558	bacterial-type flagellum-dependent cell motility
FI644_RS24855	COG1815	bacterial-type flagellum-dependent cell motility
FI644_RS24860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FI644_RS24865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FI644_RS24870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FI644_RS24875	COG4974	Belongs to the 'phage' integrase family
FI644_RS24880	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FI644_RS24885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FI644_RS24890	COG0758	DNA mediated transformation
FI644_RS24895	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FI644_RS24900	COG0045	succinate-CoA ligase (ADP-forming) activity
FI644_RS24905	COG2257	FlhB HrpN YscU SpaS Family
FI644_RS24930	COG0335	large ribosomal subunit rRNA binding
FI644_RS24935	COG0336	Belongs to the RNA methyltransferase TrmD family
FI644_RS24940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FI644_RS24950	COG1837	Belongs to the UPF0109 family
FI644_RS24960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FI644_RS24965	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FI644_RS24970	COG0552	protein localization to endoplasmic reticulum
FI644_RS24975	COG1196	nuclear chromosome segregation
FI644_RS24980	COG0571	ribonuclease III activity
FI644_RS24990	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS24995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FI644_RS25000	COG0416	fatty acid biosynthetic process
FI644_RS25005	COG1349	DNA-binding transcription factor activity
FI644_RS25010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FI644_RS25015	COG1461	Dihydroxyacetone kinase
FI644_RS25020	COG1302	Protein conserved in bacteria
FI644_RS25025	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FI644_RS25035	COG1564	THIamine pyrophosphokinase
FI644_RS25040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FI644_RS25045	COG1162	GTPase activity
FI644_RS25050	COG0515	serine threonine protein kinase
FI644_RS25050	COG2815	serine threonine protein kinase
FI644_RS25055	COG0631	protein serine/threonine phosphatase activity
FI644_RS25060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FI644_RS25065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FI644_RS25065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FI644_RS25070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FI644_RS25080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FI644_RS25085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FI644_RS25095	COG0194	GDP metabolic process
FI644_RS25105	COG1561	YicC-like family, N-terminal region
FI644_RS25110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FI644_RS25115	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FI644_RS25125	COG0284	orotidine-5'-phosphate decarboxylase activity
FI644_RS25135	COG0543	2 iron, 2 sulfur cluster binding
FI644_RS25150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FI644_RS25155	COG0540	Belongs to the ATCase OTCase family
FI644_RS25165	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FI644_RS25170	COG0564	pseudouridine synthase activity
FI644_RS25190	COG3599	regulation of cell shape
FI644_RS25195	COG2302	S4 RNA-binding domain
FI644_RS25200	COG0762	integral membrane protein
FI644_RS25205	COG1799	cell septum assembly
FI644_RS25210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FI644_RS25215	COG1496	oxidoreductase activity
FI644_RS25220	COG1873	PFAM PRC-barrel domain
FI644_RS25225	COG1191	sigma factor activity
FI644_RS25230	COG1191	sigma factor activity
FI644_RS25245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FI644_RS25250	COG0849	cell division
FI644_RS25255	COG3856	small basic protein
FI644_RS25260	COG3879	Bacterial protein of unknown function (DUF881)
FI644_RS25265	COG3879	Bacterial protein of unknown function (DUF881)
FI644_RS25270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FI644_RS25275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FI644_RS25280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FI644_RS25285	COG0772	Belongs to the SEDS family
FI644_RS25290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FI644_RS25295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FI644_RS25310	COG0768	penicillin binding
FI644_RS25315	COG0768	penicillin binding
FI644_RS25320	COG4839	cell division protein FtsL
FI644_RS25325	COG0275	rRNA processing
FI644_RS25330	COG2001	Belongs to the MraZ family
FI644_RS25335	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FI644_RS25345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FI644_RS25350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FI644_RS25355	COG0511	ligase activity, forming carbon-carbon bonds
FI644_RS25360	COG0439	Biotin carboxylase
FI644_RS25365	COG0454	-acetyltransferase
FI644_RS25375	COG1024	Enoyl-CoA hydratase
FI644_RS25380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FI644_RS25385	COG1399	metal-binding, possibly nucleic acid-binding protein
FI644_RS25395	COG3480	Lon protease (S16) C-terminal proteolytic domain
FI644_RS25400	COG1752	Esterase of the alpha-beta hydrolase superfamily
FI644_RS25405	COG3314	Sporulation integral membrane protein YlbJ
FI644_RS25410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FI644_RS25415	COG0742	ribosomal rna small subunit methyltransferase
FI644_RS25430	COG4471	UPF0298 protein
FI644_RS25435	COG3679	Belongs to the UPF0342 family
FI644_RS25465	COG2340	Cysteine-rich secretory protein family
FI644_RS25485	COG3336	cytochrome c oxidase
FI644_RS25515	COG1612	heme a metabolic process
FI644_RS25520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FI644_RS25525	COG0772	Belongs to the SEDS family
FI644_RS25530	COG4838	Belongs to the UPF0358 family
FI644_RS25535	COG2066	Belongs to the glutaminase family
FI644_RS25540	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FI644_RS25545	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FI644_RS25560	COG4896	Protein conserved in bacteria
FI644_RS25575	COG1217	gtp-binding protein TYPA
FI644_RS25585	COG0483	inositol monophosphate 1-phosphatase activity
FI644_RS25595	COG4493	Belongs to the UPF0637 family
FI644_RS25610	COG1982	Orn Lys Arg decarboxylase major
FI644_RS25640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS25650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FI644_RS25655	COG0022	dehydrogenase e1 component
FI644_RS25675	COG0242	peptide deformylase activity
FI644_RS25680	COG0561	phosphatase activity
FI644_RS25690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FI644_RS25695	COG0569	domain protein
FI644_RS25700	COG1132	(ABC) transporter
FI644_RS25705	COG1132	(ABC) transporter
FI644_RS25710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FI644_RS25715	COG0450	alkyl hydroperoxide reductase
FI644_RS25720	COG0583	DNA-binding transcription factor activity
FI644_RS25725	COG0517	IMP dehydrogenase activity
FI644_RS25730	COG4703	Protein of unknown function (DUF1797)
FI644_RS25745	COG2200	EAL domain
FI644_RS25750	COG1027	Aspartate ammonia-lyase
FI644_RS25755	COG1028	Short-chain dehydrogenase reductase Sdr
FI644_RS25760	COG1408	metallophosphoesterase
FI644_RS25765	COG5001	Diguanylate cyclase
FI644_RS25765	COG3300	MHYT domain
FI644_RS25785	COG0784	Response regulator, receiver
FI644_RS25785	COG0835	chemotaxis
FI644_RS25790	COG1714	RDD family
FI644_RS25800	COG2084	Dehydrogenase
FI644_RS25830	COG0714	Associated with various cellular activities
FI644_RS25840	COG4873	Protein conserved in bacteria
FI644_RS25855	COG3949	Membrane
FI644_RS25860	COG0542	response to heat
FI644_RS25870	COG1846	Transcriptional regulator
FI644_RS25875	COG3852	Histidine kinase
FI644_RS25880	COG2223	nitrite transmembrane transporter activity
FI644_RS25895	COG0644	oxidoreductase
FI644_RS25900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FI644_RS25920	COG5002	protein histidine kinase activity
FI644_RS25925	COG0840	transmembrane signaling receptor activity
FI644_RS25930	COG0674	pyruvate-flavodoxin oxidoreductase activity
FI644_RS25935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FI644_RS25940	COG3594	Acyltransferase
FI644_RS26020	COG0789	Transcriptional regulator
FI644_RS26040	COG1649	PFAM Uncharacterised BCR, COG1649
FI644_RS26065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FI644_RS26070	COG1846	Transcriptional regulator
FI644_RS26095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FI644_RS26110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FI644_RS26115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FI644_RS26135	COG1191	sigma factor activity