locus-tag	class	description
FOC77_RS00005	COG0579	oxidoreductase
FOC77_RS00010	COG1464	Belongs to the NlpA lipoprotein family
FOC77_RS00020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC77_RS00025	COG1279	arginine transmembrane transporter activity
FOC77_RS00030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS00040	COG5566	PFAM Mor transcription activator
FOC77_RS00045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC77_RS00050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC77_RS00060	COG5002	protein histidine kinase activity
FOC77_RS00080	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC77_RS00090	COG0840	transmembrane signaling receptor activity
FOC77_RS00095	COG1126	abc transporter atp-binding protein
FOC77_RS00100	COG0765	amino acid transport
FOC77_RS00110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC77_RS00115	COG2814	Major facilitator Superfamily
FOC77_RS00125	COG0733	neurotransmitter:sodium symporter activity
FOC77_RS00135	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC77_RS00140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC77_RS00145	COG1696	Membrane protein involved in D-alanine export
FOC77_RS00150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC77_RS00160	COG0745	RESPONSE REGULATOR receiver
FOC77_RS00165	COG5002	protein histidine kinase activity
FOC77_RS00170	COG4221	oxidoreductase activity
FOC77_RS00175	COG0789	Transcriptional regulator
FOC77_RS00185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC77_RS00190	COG2169	Transcriptional regulator
FOC77_RS00200	COG1126	abc transporter atp-binding protein
FOC77_RS00205	COG0765	amino acid transport
FOC77_RS00210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS00225	COG0697	spore germination
FOC77_RS00255	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS00265	COG0697	spore germination
FOC77_RS00270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS00360	COG2003	Belongs to the UPF0758 family
FOC77_RS00385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOC77_RS00395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC77_RS00400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC77_RS00405	COG4853	Protein conserved in bacteria
FOC77_RS00410	COG4863	YycH protein
FOC77_RS00415	COG5002	protein histidine kinase activity
FOC77_RS00420	COG0745	RESPONSE REGULATOR receiver
FOC77_RS00450	COG0305	Participates in initiation and elongation during chromosome replication
FOC77_RS00455	COG0359	binds to the 23S rRNA
FOC77_RS00460	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC77_RS00465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC77_RS00475	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC77_RS00480	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS00485	COG0012	GTP binding
FOC77_RS00490	COG4481	Protein conserved in bacteria
FOC77_RS00495	COG0668	transmembrane transport
FOC77_RS00505	COG1475	DNA binding
FOC77_RS00510	COG1192	Involved in chromosome partitioning
FOC77_RS00515	COG1475	DNA binding
FOC77_RS00535	COG1847	R3H domain protein
FOC77_RS00545	COG0594	ribonuclease P activity
FOC77_RS00550	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC77_RS00560	COG0592	DNA-directed DNA polymerase activity
FOC77_RS00565	COG2501	S4 domain
FOC77_RS00570	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC77_RS00580	COG0187	DNA topoisomerase II activity
FOC77_RS00585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC77_RS00590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOC77_RS00625	COG0516	GMP reductase activity
FOC77_RS00625	COG0517	IMP dehydrogenase activity
FOC77_RS00640	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FOC77_RS00645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC77_RS00655	COG1428	Deoxynucleoside kinase
FOC77_RS00660	COG1428	Deoxynucleoside kinase
FOC77_RS00665	COG0352	thiamine-phosphate diphosphorylase activity
FOC77_RS00670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC77_RS00675	COG2104	thiamine diphosphate biosynthetic process
FOC77_RS00680	COG2022	thiamine diphosphate biosynthetic process
FOC77_RS00685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC77_RS00690	COG1388	LysM domain
FOC77_RS00690	COG3858	chitin binding
FOC77_RS00695	COG1335	isochorismatase
FOC77_RS00700	COG0590	tRNA wobble adenosine to inosine editing
FOC77_RS00710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC77_RS00715	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOC77_RS00720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC77_RS00765	COG1982	Orn Lys Arg decarboxylase major
FOC77_RS00775	COG3870	Protein conserved in bacteria
FOC77_RS00785	COG0470	DNA polymerase III
FOC77_RS00790	COG1774	PSP1 C-terminal conserved region
FOC77_RS00795	COG4467	Involved in initiation control of chromosome replication
FOC77_RS00800	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC77_RS00810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC77_RS00815	COG2002	toxin-antitoxin pair type II binding
FOC77_RS00825	COG0084	hydrolase, TatD family'
FOC77_RS00830	COG3584	3D domain protein
FOC77_RS00830	COG3583	domain protein
FOC77_RS00840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC77_RS00850	COG4466	Protein conserved in bacteria
FOC77_RS00860	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOC77_RS00865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC77_RS00870	COG0251	oxidation-reduction process
FOC77_RS00875	COG2088	sporulation resulting in formation of a cellular spore
FOC77_RS00880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC77_RS00885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC77_RS00890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOC77_RS00905	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC77_RS00910	COG2002	toxin-antitoxin pair type II binding
FOC77_RS00915	COG2188	Transcriptional regulator
FOC77_RS00925	COG2244	polysaccharide biosynthetic process
FOC77_RS00930	COG3956	TIGRFAM MazG family protein
FOC77_RS00935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC77_RS00950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOC77_RS00955	COG1098	S1 RNA binding domain
FOC77_RS00965	COG2208	phosphoserine phosphatase activity
FOC77_RS00970	COG2304	oxidoreductase activity
FOC77_RS00975	COG0515	serine threonine protein kinase
FOC77_RS00980	COG0037	tRNA processing
FOC77_RS00990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC77_RS00995	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOC77_RS01000	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOC77_RS01005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC77_RS01010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC77_RS01015	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC77_RS01020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC77_RS01025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC77_RS01030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC77_RS01035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC77_RS01040	COG1396	sequence-specific DNA binding
FOC77_RS01045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC77_RS01050	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOC77_RS01135	COG3880	PFAM UvrB UvrC protein
FOC77_RS01140	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FOC77_RS01145	COG0542	response to heat
FOC77_RS01150	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC77_RS01155	COG4956	integral membrane protein (PIN domain superfamily)
FOC77_RS01160	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOC77_RS01165	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC77_RS01170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC77_RS01175	COG1045	serine acetyltransferase
FOC77_RS01180	COG0215	cysteine-tRNA ligase activity
FOC77_RS01190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC77_RS01195	COG3688	RNA-binding protein containing a PIN domain
FOC77_RS01205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC77_RS01210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC77_RS01215	COG0250	Participates in transcription elongation, termination and antitermination
FOC77_RS01220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC77_RS01225	COG0081	regulation of translation
FOC77_RS01230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC77_RS01235	COG0222	ribosome binding
FOC77_RS01240	COG2813	Specifically methylates the guanine in position
FOC77_RS01250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC77_RS01255	COG1358	cellular component organization or biogenesis
FOC77_RS01260	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC77_RS01265	COG0049	tRNA binding
FOC77_RS01275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC77_RS01280	COG0051	transcription antitermination factor activity, RNA binding
FOC77_RS01285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOC77_RS01290	COG0088	Forms part of the polypeptide exit tunnel
FOC77_RS01300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOC77_RS01305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC77_RS01320	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC77_RS01325	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC77_RS01330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC77_RS01360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC77_RS01365	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC77_RS01370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC77_RS01375	COG1841	ribosomal large subunit assembly
FOC77_RS01385	COG0201	protein transport
FOC77_RS01390	COG0563	adenylate kinase activity
FOC77_RS01395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC77_RS01400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC77_RS01405	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC77_RS01415	COG0202	RNA polymerase activity
FOC77_RS01420	COG0203	ribosomal protein L17
FOC77_RS01425	COG1122	ATPase activity
FOC77_RS01430	COG1122	ATPase activity
FOC77_RS01435	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC77_RS01445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC77_RS01450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC77_RS01465	COG0346	lactoylglutathione lyase activity
FOC77_RS01475	COG0789	Transcriptional regulator
FOC77_RS01480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC77_RS01515	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC77_RS01520	COG0489	protein tyrosine kinase activity
FOC77_RS01530	COG0726	polysaccharide deacetylase
FOC77_RS01605	COG1595	DNA-templated transcription, initiation
FOC77_RS01610	COG5662	AntiSigma factor
FOC77_RS01615	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC77_RS01620	COG4856	YbbR-like protein
FOC77_RS01625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC77_RS01630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC77_RS01635	COG0596	Alpha beta hydrolase
FOC77_RS01640	COG1510	regulation of RNA biosynthetic process
FOC77_RS01645	COG0463	Glycosyl transferase, family 2
FOC77_RS01675	COG1846	Transcriptional regulator
FOC77_RS01690	COG0778	Nitroreductase
FOC77_RS01705	COG0745	RESPONSE REGULATOR receiver
FOC77_RS01710	COG2205	protein histidine kinase activity
FOC77_RS01735	COG0745	RESPONSE REGULATOR receiver
FOC77_RS01740	COG0642	Histidine kinase
FOC77_RS01760	COG1733	regulation of RNA biosynthetic process
FOC77_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS01785	COG2807	transmembrane transport
FOC77_RS01795	COG4607	ABC-type enterochelin transport system periplasmic component
FOC77_RS01800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS01805	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS01810	COG1120	ATPase activity
FOC77_RS01830	COG0730	response to heat
FOC77_RS01835	COG3339	Conserved Protein
FOC77_RS01855	COG2210	Belongs to the sulfur carrier protein TusA family
FOC77_RS01865	COG1114	Component of the transport system for branched-chain amino acids
FOC77_RS01870	COG0840	transmembrane signaling receptor activity
FOC77_RS01870	COG3290	protein histidine kinase activity
FOC77_RS01885	COG0519	Catalyzes the synthesis of GMP from XMP
FOC77_RS01890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC77_RS01900	COG1595	DNA-templated transcription, initiation
FOC77_RS01910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC77_RS01920	COG0456	acetyltransferase
FOC77_RS01930	COG1595	DNA-templated transcription, initiation
FOC77_RS01940	COG1316	TRANSCRIPTIONal
FOC77_RS01950	COG0454	-acetyltransferase
FOC77_RS01975	COG1011	Hydrolase
FOC77_RS01985	COG1609	Transcriptional regulator
FOC77_RS01990	COG2182	Extracellular solute-binding protein
FOC77_RS01995	COG1175	transmembrane transport
FOC77_RS02000	COG3833	ABC-type maltose transport systems, permease component
FOC77_RS02005	COG1874	Beta-galactosidase
FOC77_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS02020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC77_RS02025	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOC77_RS02030	COG0583	DNA-binding transcription factor activity
FOC77_RS02045	COG0175	sulfate reduction
FOC77_RS02050	COG0306	phosphate transporter
FOC77_RS02055	COG2046	Belongs to the sulfate adenylyltransferase family
FOC77_RS02060	COG0529	Catalyzes the synthesis of activated sulfate
FOC77_RS02080	COG2205	protein histidine kinase activity
FOC77_RS02080	COG0784	Response regulator, receiver
FOC77_RS02120	COG2801	Transposase and inactivated derivatives
FOC77_RS02140	COG2404	hydrolase activity, acting on ester bonds
FOC77_RS02155	COG1657	PFAM Prenyltransferase squalene oxidase
FOC77_RS02160	COG0017	Asparaginyl-tRNA synthetase
FOC77_RS02165	COG3386	PFAM SMP-30 Gluconolaconase
FOC77_RS02175	COG0659	secondary active sulfate transmembrane transporter activity
FOC77_RS02185	COG3620	sequence-specific DNA binding
FOC77_RS02195	COG1263	PTS System
FOC77_RS02195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS02195	COG2190	(PTS) system
FOC77_RS02220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS02245	COG4149	molybdate abc transporter
FOC77_RS02250	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC77_RS02255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC77_RS02290	COG1252	NADH dehydrogenase
FOC77_RS02305	COG1122	ATPase activity
FOC77_RS02330	COG2244	polysaccharide biosynthetic process
FOC77_RS02335	COG0297	glycogen (starch) synthase activity
FOC77_RS02335	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS02340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC77_RS02345	COG3307	-O-antigen
FOC77_RS02355	COG1215	transferase activity, transferring glycosyl groups
FOC77_RS02360	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS02365	COG1959	2 iron, 2 sulfur cluster binding
FOC77_RS02385	COG2362	D-Aminopeptidase
FOC77_RS02390	COG0601	transmembrane transport
FOC77_RS02395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC77_RS02400	COG0444	Belongs to the ABC transporter superfamily
FOC77_RS02405	COG4166	transmembrane transport
FOC77_RS02410	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC77_RS02415	COG4948	Mandelate Racemase Muconate Lactonizing
FOC77_RS02420	COG0791	NLP P60 protein
FOC77_RS02425	COG4608	Belongs to the ABC transporter superfamily
FOC77_RS02435	COG1120	ATPase activity
FOC77_RS02440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC77_RS02450	COG0667	Aldo Keto reductase
FOC77_RS02455	COG0129	dihydroxy-acid dehydratase activity
FOC77_RS02460	COG0628	permease
FOC77_RS02470	COG1253	flavin adenine dinucleotide binding
FOC77_RS02480	COG3711	transcriptional antiterminator
FOC77_RS02485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS02490	COG0246	Mannitol dehydrogenase
FOC77_RS02495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC77_RS02500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC77_RS02505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC77_RS02520	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS02525	COG4605	iron ion homeostasis
FOC77_RS02530	COG4604	ABC transporter, ATP-binding protein
FOC77_RS02535	COG4607	ABC-type enterochelin transport system periplasmic component
FOC77_RS02540	COG0673	inositol 2-dehydrogenase activity
FOC77_RS02545	COG1940	carbohydrate kinase activity
FOC77_RS02550	COG3850	Histidine kinase
FOC77_RS02550	COG5002	protein histidine kinase activity
FOC77_RS02555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC77_RS02560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC77_RS02590	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC77_RS02595	COG1177	transmembrane transport
FOC77_RS02600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC77_RS02605	COG2861	carbohydrate metabolic process
FOC77_RS02610	COG0668	transmembrane transport
FOC77_RS02615	COG0569	domain protein
FOC77_RS02620	COG0783	Belongs to the Dps family
FOC77_RS02625	COG0772	Belongs to the SEDS family
FOC77_RS02630	COG2239	Acts as a magnesium transporter
FOC77_RS02635	COG0402	S-adenosylhomocysteine deaminase activity
FOC77_RS02650	COG1489	DNA binding
FOC77_RS02655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC77_RS02660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS02665	COG1120	ATPase activity
FOC77_RS02670	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOC77_RS02685	COG1492	cobalamin metabolic process
FOC77_RS02690	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FOC77_RS02695	COG0588	phosphoglycerate mutase activity
FOC77_RS02705	COG2096	Adenosyltransferase
FOC77_RS02725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC77_RS02735	COG0513	Belongs to the DEAD box helicase family
FOC77_RS02740	COG3402	PFAM membrane-flanked domain
FOC77_RS02745	COG3428	Bacterial PH domain
FOC77_RS02750	COG0705	Rhomboid family
FOC77_RS02755	COG0736	holo-[acyl-carrier-protein] synthase activity
FOC77_RS02760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC77_RS02770	COG0864	Transcriptional regulator
FOC77_RS02775	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC77_RS02785	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS02790	COG2172	sigma factor antagonist activity
FOC77_RS02795	COG2208	phosphoserine phosphatase activity
FOC77_RS02800	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS02805	COG2172	sigma factor antagonist activity
FOC77_RS02810	COG1191	sigma factor activity
FOC77_RS02815	COG2208	phosphoserine phosphatase activity
FOC77_RS02820	COG2183	response to ionizing radiation
FOC77_RS02830	COG3091	SprT-like family
FOC77_RS02910	COG0802	atpase or kinase
FOC77_RS02915	COG1214	PFAM Peptidase M22, glycoprotease
FOC77_RS02920	COG0456	acetyltransferase
FOC77_RS02930	COG0488	(ABC) transporter
FOC77_RS02935	COG0315	cyclic pyranopterin monophosphate synthase activity
FOC77_RS02940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOC77_RS02950	COG1266	CAAX protease self-immunity
FOC77_RS02955	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC77_RS02960	COG0459	protein refolding
FOC77_RS02965	COG0582	viral genome integration into host DNA
FOC77_RS02970	COG1113	amino acid transport
FOC77_RS02980	COG0346	lactoylglutathione lyase activity
FOC77_RS03010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS03015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS03015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS03015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS03025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC77_RS03045	COG3715	PTS system
FOC77_RS03050	COG3716	PTS system mannose fructose sorbose family IID component
FOC77_RS03055	COG0673	inositol 2-dehydrogenase activity
FOC77_RS03060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC77_RS03065	COG0277	FAD linked oxidase domain protein
FOC77_RS03080	COG0840	transmembrane signaling receptor activity
FOC77_RS03080	COG3290	protein histidine kinase activity
FOC77_RS03090	COG3290	protein histidine kinase activity
FOC77_RS03095	COG4565	transcriptional regulatory protein
FOC77_RS03105	COG0281	malic enzyme
FOC77_RS03115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOC77_RS03130	COG3842	ATPase activity
FOC77_RS03135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC77_RS03135	COG1796	DNA polymerase
FOC77_RS03140	COG1533	DNA photolyase activity
FOC77_RS03150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC77_RS03155	COG3871	stress protein (general stress protein 26)
FOC77_RS03160	COG4294	response to UV
FOC77_RS03175	COG2211	Major facilitator Superfamily
FOC77_RS03185	COG0702	epimerase
FOC77_RS03200	COG1312	Catalyzes the dehydration of D-mannonate
FOC77_RS03210	COG1904	glucuronate isomerase
FOC77_RS03215	COG2190	(PTS) system
FOC77_RS03215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS03215	COG1263	PTS System
FOC77_RS03220	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS03225	COG3711	transcriptional antiterminator
FOC77_RS03235	COG2310	stress, protein
FOC77_RS03240	COG0714	Associated with various cellular activities
FOC77_RS03245	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC77_RS03250	COG1305	Transglutaminase-like
FOC77_RS03255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC77_RS03255	COG0519	Catalyzes the synthesis of GMP from XMP
FOC77_RS03260	COG0730	response to heat
FOC77_RS03265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOC77_RS03270	COG0517	IMP dehydrogenase activity
FOC77_RS03275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC77_RS03275	COG0574	Belongs to the PEP-utilizing enzyme family
FOC77_RS03280	COG2252	PERMEase
FOC77_RS03285	COG3711	transcriptional antiterminator
FOC77_RS03290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS03290	COG1263	PTS System
FOC77_RS03290	COG2190	(PTS) system
FOC77_RS03310	COG1131	(ABC) transporter
FOC77_RS03335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC77_RS03360	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FOC77_RS03370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC77_RS03375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC77_RS03380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC77_RS03385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOC77_RS03390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC77_RS03395	COG0047	phosphoribosylformylglycinamidine synthase activity
FOC77_RS03405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC77_RS03410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC77_RS03415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC77_RS03420	COG0138	bifunctional purine biosynthesis protein purh
FOC77_RS03425	COG0151	Belongs to the GarS family
FOC77_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS03445	COG1470	cell adhesion involved in biofilm formation
FOC77_RS03450	COG4496	protein, YerC YecD
FOC77_RS03455	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FOC77_RS03460	COG0210	DNA helicase
FOC77_RS03465	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC77_RS03470	COG4851	CamS sex pheromone cAM373 precursor
FOC77_RS03475	COG5506	Protein of unknown function (DUF1694)
FOC77_RS03480	COG1764	response to oxidative stress
FOC77_RS03485	COG1846	Transcriptional regulator
FOC77_RS03490	COG2720	vancomycin resistance protein
FOC77_RS03495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOC77_RS03505	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOC77_RS03525	COG1595	DNA-templated transcription, initiation
FOC77_RS03545	COG1597	lipid kinase activity
FOC77_RS03565	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC77_RS03620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC77_RS03635	COG0305	Participates in initiation and elongation during chromosome replication
FOC77_RS03685	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC77_RS03760	COG0740	serine-type endopeptidase activity
FOC77_RS03835	COG1876	peptidase activity
FOC77_RS03880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC77_RS03895	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
FOC77_RS03900	COG2205	protein histidine kinase activity
FOC77_RS03910	COG0456	acetyltransferase
FOC77_RS03915	COG3584	3D domain protein
FOC77_RS03915	COG1388	LysM domain
FOC77_RS03935	COG2972	Histidine kinase
FOC77_RS03960	COG0166	Belongs to the GPI family
FOC77_RS03970	COG1733	regulation of RNA biosynthetic process
FOC77_RS03975	COG2514	catechol 2,3-dioxygenase activity
FOC77_RS03990	COG1785	Belongs to the alkaline phosphatase family
FOC77_RS03995	COG1794	racemase activity, acting on amino acids and derivatives
FOC77_RS04000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS04005	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC77_RS04015	COG3279	Response regulator of the LytR AlgR family
FOC77_RS04035	COG1695	Transcriptional regulator
FOC77_RS04060	COG0515	serine threonine protein kinase
FOC77_RS04065	COG1132	(ABC) transporter
FOC77_RS04080	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC77_RS04090	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOC77_RS04095	COG4122	O-methyltransferase activity
FOC77_RS04100	COG0583	DNA-binding transcription factor activity
FOC77_RS04110	COG2814	Major facilitator Superfamily
FOC77_RS04115	COG0527	aspartate kinase activity
FOC77_RS04125	COG0765	amino acid transport
FOC77_RS04130	COG1126	abc transporter atp-binding protein
FOC77_RS04140	COG1473	amidohydrolase
FOC77_RS04145	COG1473	amidohydrolase
FOC77_RS04150	COG0444	Belongs to the ABC transporter superfamily
FOC77_RS04155	COG4608	Belongs to the ABC transporter superfamily
FOC77_RS04160	COG0601	transmembrane transport
FOC77_RS04165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC77_RS04175	COG1132	(ABC) transporter
FOC77_RS04180	COG1132	(ABC) transporter
FOC77_RS04185	COG2357	RelA SpoT domain protein
FOC77_RS04190	COG0513	Belongs to the DEAD box helicase family
FOC77_RS04205	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOC77_RS04210	COG0697	spore germination
FOC77_RS04240	COG2197	response regulator
FOC77_RS04245	COG2244	polysaccharide biosynthetic process
FOC77_RS04260	COG0598	Magnesium transport protein CorA
FOC77_RS04265	COG1607	acyl-coa hydrolase
FOC77_RS04275	COG0670	Belongs to the BI1 family
FOC77_RS04280	COG1970	mechanosensitive ion channel activity
FOC77_RS04285	COG1254	Belongs to the acylphosphatase family
FOC77_RS04295	COG2309	aminopeptidase activity
FOC77_RS04300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC77_RS04305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC77_RS04305	COG0551	DNA topoisomerase type I activity
FOC77_RS04320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC77_RS04325	COG1360	Flagellar Motor Protein
FOC77_RS04330	COG1522	sequence-specific DNA binding
FOC77_RS04330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS04335	COG2313	pseudouridylate synthase activity
FOC77_RS04340	COG1396	sequence-specific DNA binding
FOC77_RS04355	COG1396	sequence-specific DNA binding
FOC77_RS04360	COG2188	Transcriptional regulator
FOC77_RS04365	COG0693	protein deglycase activity
FOC77_RS04370	COG0024	Methionine aminopeptidase
FOC77_RS04375	COG4840	Belongs to the UPF0435 family
FOC77_RS04380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC77_RS04390	COG1295	ribonuclease BN
FOC77_RS04395	COG2217	Heavy metal translocating P-type atpase
FOC77_RS04400	COG0477	Major facilitator Superfamily
FOC77_RS04405	COG0387	Pfam Sodium calcium exchanger
FOC77_RS04410	COG2364	Membrane
FOC77_RS04420	COG0535	radical SAM domain protein
FOC77_RS04435	COG1309	transcriptional regulator
FOC77_RS04445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC77_RS04450	COG1116	anion transmembrane transporter activity
FOC77_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS04475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC77_RS04480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS04490	COG1959	2 iron, 2 sulfur cluster binding
FOC77_RS04505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC77_RS04510	COG4974	Belongs to the 'phage' integrase family
FOC77_RS04515	COG0583	DNA-binding transcription factor activity
FOC77_RS04520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC77_RS04525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FOC77_RS04530	COG0789	Transcriptional regulator
FOC77_RS04535	COG1266	CAAX protease self-immunity
FOC77_RS04575	COG4842	Belongs to the WXG100 family
FOC77_RS04580	COG5417	Belongs to the EsaB family
FOC77_RS04585	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC77_RS04590	COG0433	COG0433 Predicted ATPase
FOC77_RS04590	COG1674	ftsk spoiiie
FOC77_RS04595	COG1511	domain protein
FOC77_RS04605	COG0488	(ABC) transporter
FOC77_RS04610	COG3940	Belongs to the glycosyl hydrolase 43 family
FOC77_RS04620	COG0737	Belongs to the 5'-nucleotidase family
FOC77_RS04625	COG0366	Alpha amylase catalytic
FOC77_RS04640	COG4807	Protein conserved in bacteria
FOC77_RS04650	COG0583	DNA-binding transcription factor activity
FOC77_RS04675	COG0517	IMP dehydrogenase activity
FOC77_RS04675	COG1125	glycine betaine transport
FOC77_RS04680	COG1174	glycine betaine transport
FOC77_RS04690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC77_RS04695	COG0573	inorganic phosphate transmembrane transporter activity
FOC77_RS04700	COG0581	inorganic phosphate transmembrane transporter activity
FOC77_RS04705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC77_RS04720	COG0745	RESPONSE REGULATOR receiver
FOC77_RS04720	COG2972	Histidine kinase
FOC77_RS04725	COG2207	Transcriptional regulator
FOC77_RS04725	COG4753	response regulator
FOC77_RS04730	COG4213	ABC transporter substrate-binding protein
FOC77_RS04735	COG1129	ABC transporter
FOC77_RS04740	COG4214	carbohydrate transport
FOC77_RS04745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC77_RS04750	COG2211	Major facilitator Superfamily
FOC77_RS04765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC77_RS04775	COG0702	epimerase
FOC77_RS04780	COG1733	regulation of RNA biosynthetic process
FOC77_RS04790	COG0765	amino acid transport
FOC77_RS04805	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC77_RS04810	COG0322	excinuclease ABC activity
FOC77_RS04830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOC77_RS04835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC77_RS04840	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FOC77_RS04845	COG4260	virion core protein, lumpy skin disease virus
FOC77_RS04875	COG3328	transposase activity
FOC77_RS04885	COG3534	alpha-L-arabinofuranosidase
FOC77_RS04895	COG1780	Probably involved in ribonucleotide reductase function
FOC77_RS04900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC77_RS04905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC77_RS04910	COG1595	DNA-templated transcription, initiation
FOC77_RS04925	COG1132	(ABC) transporter
FOC77_RS04930	COG1132	(ABC) transporter
FOC77_RS04955	COG0840	transmembrane signaling receptor activity
FOC77_RS04975	COG3275	phosphorelay sensor kinase activity
FOC77_RS04980	COG3279	Response regulator of the LytR AlgR family
FOC77_RS04985	COG2223	nitrite transmembrane transporter activity
FOC77_RS04990	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FOC77_RS04995	COG3853	Toxic anion resistance protein (TelA)
FOC77_RS05000	COG4708	membrane
FOC77_RS05015	COG1136	(ABC) transporter
FOC77_RS05020	COG0577	efflux transmembrane transporter activity
FOC77_RS05020	COG1136	(ABC) transporter
FOC77_RS05025	COG0745	RESPONSE REGULATOR receiver
FOC77_RS05030	COG3850	Histidine kinase
FOC77_RS05030	COG5002	protein histidine kinase activity
FOC77_RS05035	COG1607	acyl-coa hydrolase
FOC77_RS05045	COG0683	leucine binding
FOC77_RS05070	COG2706	6-phosphogluconolactonase activity
FOC77_RS05075	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC77_RS05085	COG2137	regulation of response to DNA damage stimulus
FOC77_RS05105	COG1988	membrane-bound metal-dependent
FOC77_RS05110	COG1194	a g-specific adenine glycosylase
FOC77_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS05140	COG1132	(ABC) transporter
FOC77_RS05145	COG4129	membrane
FOC77_RS05150	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOC77_RS05160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC77_RS05165	COG0735	belongs to the Fur family
FOC77_RS05260	COG4974	Belongs to the 'phage' integrase family
FOC77_RS05395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC77_RS05395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC77_RS05420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOC77_RS05435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC77_RS05440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC77_RS05465	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC77_RS05485	COG0270	DNA (cytosine-5-)-methyltransferase activity
FOC77_RS05635	COG1388	LysM domain
FOC77_RS05635	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC77_RS05760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOC77_RS05780	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOC77_RS05785	COG2801	Transposase and inactivated derivatives
FOC77_RS05820	COG0110	maltose O-acetyltransferase activity
FOC77_RS05835	COG0398	Pfam SNARE associated Golgi protein
FOC77_RS05840	COG0745	RESPONSE REGULATOR receiver
FOC77_RS05845	COG5002	protein histidine kinase activity
FOC77_RS05845	COG0642	Histidine kinase
FOC77_RS05855	COG1132	(ABC) transporter
FOC77_RS05865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS05885	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC77_RS05900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS05905	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS05910	COG3711	transcriptional antiterminator
FOC77_RS05910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS05965	COG1304	FMN binding
FOC77_RS05975	COG1846	Transcriptional regulator
FOC77_RS05990	COG0477	Major facilitator Superfamily
FOC77_RS05995	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC77_RS06000	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC77_RS06000	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC77_RS06020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC77_RS06025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS06030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS06040	COG0667	Aldo Keto reductase
FOC77_RS06050	COG2207	Transcriptional regulator
FOC77_RS06055	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC77_RS06060	COG4977	sequence-specific DNA binding
FOC77_RS06065	COG0745	RESPONSE REGULATOR receiver
FOC77_RS06070	COG2205	protein histidine kinase activity
FOC77_RS06075	COG1136	(ABC) transporter
FOC77_RS06080	COG0577	efflux transmembrane transporter activity
FOC77_RS06085	COG1902	pentaerythritol trinitrate reductase activity
FOC77_RS06090	COG3711	transcriptional antiterminator
FOC77_RS06095	COG1263	PTS System
FOC77_RS06095	COG2190	(PTS) system
FOC77_RS06095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS06100	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS06105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC77_RS06110	COG1984	allophanate hydrolase subunit 2
FOC77_RS06115	COG2814	Major facilitator Superfamily
FOC77_RS06135	COG1349	DNA-binding transcription factor activity
FOC77_RS06140	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FOC77_RS06150	COG1132	(ABC) transporter
FOC77_RS06155	COG0641	radical SAM
FOC77_RS06165	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS06210	COG0745	RESPONSE REGULATOR receiver
FOC77_RS06215	COG2205	protein histidine kinase activity
FOC77_RS06230	COG0596	Alpha beta hydrolase
FOC77_RS06235	COG2208	phosphoserine phosphatase activity
FOC77_RS06240	COG1846	Transcriptional regulator
FOC77_RS06245	COG0346	lactoylglutathione lyase activity
FOC77_RS06250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC77_RS06255	COG0346	lactoylglutathione lyase activity
FOC77_RS06260	COG0400	carboxylic ester hydrolase activity
FOC77_RS06265	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC77_RS06275	COG1378	Sugar-specific transcriptional regulator TrmB
FOC77_RS06285	COG2391	methyltransferase activity
FOC77_RS06290	COG0737	Belongs to the 5'-nucleotidase family
FOC77_RS06305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC77_RS06310	COG0431	NADPH-dependent FMN reductase
FOC77_RS06325	COG0741	lytic transglycosylase activity
FOC77_RS06330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC77_RS06350	COG4221	oxidoreductase activity
FOC77_RS06355	COG0789	Transcriptional regulator
FOC77_RS06365	COG1733	regulation of RNA biosynthetic process
FOC77_RS06370	COG0586	Pfam SNARE associated Golgi protein
FOC77_RS06380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC77_RS06390	COG1063	alcohol dehydrogenase
FOC77_RS06400	COG2116	formate transmembrane transporter activity
FOC77_RS06415	COG3382	B3 4 domain protein
FOC77_RS06420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC77_RS06435	COG0778	Nitroreductase
FOC77_RS06440	COG2766	serine protein kinase
FOC77_RS06470	COG2832	Protein of unknown function (DUF454)
FOC77_RS06485	COG0667	Aldo Keto reductase
FOC77_RS06490	COG1917	Cupin 2, conserved barrel domain protein
FOC77_RS06490	COG4977	sequence-specific DNA binding
FOC77_RS06495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS06495	COG1263	PTS System
FOC77_RS06505	COG0500	methyltransferase
FOC77_RS06520	COG0500	methyltransferase
FOC77_RS06535	COG0456	acetyltransferase
FOC77_RS06540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC77_RS06565	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC77_RS06570	COG2323	membrane
FOC77_RS06590	COG1733	regulation of RNA biosynthetic process
FOC77_RS06595	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS06615	COG2329	Antibiotic biosynthesis monooxygenase
FOC77_RS06620	COG2207	Transcriptional regulator
FOC77_RS06620	COG1917	Cupin 2, conserved barrel domain protein
FOC77_RS06630	COG2315	Protein conserved in bacteria
FOC77_RS06650	COG3959	Transketolase, thiamine diphosphate binding domain
FOC77_RS06655	COG3958	Transketolase
FOC77_RS06665	COG2190	(PTS) system
FOC77_RS06665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS06665	COG1263	PTS System
FOC77_RS06675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC77_RS06685	COG2197	response regulator
FOC77_RS06690	COG4585	Histidine kinase
FOC77_RS06695	COG3239	Fatty acid desaturase
FOC77_RS06700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC77_RS06710	COG1396	sequence-specific DNA binding
FOC77_RS06725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC77_RS06750	COG0745	RESPONSE REGULATOR receiver
FOC77_RS06755	COG5002	protein histidine kinase activity
FOC77_RS06760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS06775	COG0306	phosphate transporter
FOC77_RS06780	COG1392	Phosphate transport regulator
FOC77_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS06790	COG0656	L-ascorbic acid biosynthetic process
FOC77_RS06795	COG2261	transglycosylase associated protein
FOC77_RS06800	COG0564	pseudouridine synthase activity
FOC77_RS06810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC77_RS06820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC77_RS06820	COG3153	acetyltransferase
FOC77_RS06840	COG2252	PERMEase
FOC77_RS06850	COG1309	transcriptional regulator
FOC77_RS06855	COG2076	Multidrug Resistance protein
FOC77_RS06865	COG0395	ABC-type sugar transport system, permease component
FOC77_RS06870	COG1175	transmembrane transport
FOC77_RS06875	COG1653	transport
FOC77_RS06900	COG2378	regulation of single-species biofilm formation
FOC77_RS06915	COG0346	lactoylglutathione lyase activity
FOC77_RS06935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC77_RS06940	COG1131	(ABC) transporter
FOC77_RS06950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS06955	COG0598	Magnesium transport protein CorA
FOC77_RS06960	COG0745	RESPONSE REGULATOR receiver
FOC77_RS06965	COG1253	flavin adenine dinucleotide binding
FOC77_RS06970	COG1253	flavin adenine dinucleotide binding
FOC77_RS06975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC77_RS06980	COG5278	phosphoserine phosphatase activity
FOC77_RS06980	COG0840	transmembrane signaling receptor activity
FOC77_RS06990	COG2814	Major facilitator Superfamily
FOC77_RS06995	COG1132	(ABC) transporter
FOC77_RS07000	COG1132	(ABC) transporter
FOC77_RS07005	COG2819	hydrolase of the alpha beta superfamily
FOC77_RS07010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC77_RS07010	COG2207	Transcriptional regulator
FOC77_RS07015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC77_RS07020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS07025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS07030	COG2819	hydrolase of the alpha beta superfamily
FOC77_RS07045	COG3842	ATPase activity
FOC77_RS07050	COG2508	Transcriptional regulator
FOC77_RS07060	COG0189	ligase activity
FOC77_RS07065	COG0189	ligase activity
FOC77_RS07070	COG0189	ligase activity
FOC77_RS07090	COG0561	phosphatase activity
FOC77_RS07095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC77_RS07100	COG2252	PERMEase
FOC77_RS07105	COG4152	abc transporter atp-binding protein
FOC77_RS07110	COG1668	transmembrane transport
FOC77_RS07115	COG0420	3'-5' exonuclease activity
FOC77_RS07120	COG4717	serine-type aminopeptidase activity
FOC77_RS07155	COG1846	Transcriptional regulator
FOC77_RS07165	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOC77_RS07170	COG0537	adenosine 5'-monophosphoramidase activity
FOC77_RS07175	COG1131	(ABC) transporter
FOC77_RS07180	COG4473	ABC transporter
FOC77_RS07190	COG1473	amidohydrolase
FOC77_RS07200	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC77_RS07210	COG4585	Histidine kinase
FOC77_RS07215	COG2197	response regulator
FOC77_RS07225	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC77_RS07235	COG1309	transcriptional regulator
FOC77_RS07240	COG1511	domain protein
FOC77_RS07245	COG0095	Lipoate-protein ligase
FOC77_RS07250	COG0501	Belongs to the peptidase M48B family
FOC77_RS07270	COG0823	Involved in the tonB-independent uptake of proteins
FOC77_RS07270	COG4946	Tricorn protease homolog
FOC77_RS07270	COG1506	peptidase
FOC77_RS07280	COG0398	Pfam SNARE associated Golgi protein
FOC77_RS07335	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC77_RS07345	COG4585	Histidine kinase
FOC77_RS07350	COG2197	response regulator
FOC77_RS07355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS07360	COG1253	flavin adenine dinucleotide binding
FOC77_RS07365	COG1131	(ABC) transporter
FOC77_RS07380	COG2226	methyltransferase
FOC77_RS07385	COG1737	Transcriptional regulator
FOC77_RS07390	COG0673	inositol 2-dehydrogenase activity
FOC77_RS07395	COG0673	inositol 2-dehydrogenase activity
FOC77_RS07405	COG2207	Transcriptional regulator
FOC77_RS07415	COG1247	-acetyltransferase
FOC77_RS07430	COG0367	asparagine synthase
FOC77_RS07445	COG0697	spore germination
FOC77_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS07460	COG1666	GTP binding
FOC77_RS07465	COG2996	Protein conserved in bacteria
FOC77_RS07475	COG1307	EDD domain protein, DegV family
FOC77_RS07480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS07500	COG0561	phosphatase activity
FOC77_RS07505	COG1073	alpha beta
FOC77_RS07510	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC77_RS07515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC77_RS07520	COG0303	'Molybdopterin
FOC77_RS07525	COG1620	l-lactate permease
FOC77_RS07530	COG2186	Transcriptional regulator
FOC77_RS07535	COG0247	lactate metabolic process
FOC77_RS07540	COG1139	Iron-sulfur cluster binding protein
FOC77_RS07545	COG1556	Lactate utilization protein
FOC77_RS07550	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOC77_RS07555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC77_RS07560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC77_RS07580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOC77_RS07600	COG2267	carboxylic ester hydrolase activity
FOC77_RS07610	COG1744	ABC transporter substrate-binding protein PnrA-like
FOC77_RS07620	COG3711	transcriptional antiterminator
FOC77_RS07630	COG3730	PTS system glucitol sorbitol-specific
FOC77_RS07635	COG3732	PTS system glucitol sorbitol-specific
FOC77_RS07650	COG0561	phosphatase activity
FOC77_RS07660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC77_RS07665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC77_RS07670	COG0735	belongs to the Fur family
FOC77_RS07675	COG5504	Zn-dependent protease
FOC77_RS07685	COG0180	Tryptophanyl-tRNA synthetase
FOC77_RS07690	COG4166	transmembrane transport
FOC77_RS07695	COG0601	transmembrane transport
FOC77_RS07700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC77_RS07705	COG0444	Belongs to the ABC transporter superfamily
FOC77_RS07710	COG4608	Belongs to the ABC transporter superfamily
FOC77_RS07720	COG0456	acetyltransferase
FOC77_RS07725	COG1393	Belongs to the ArsC family
FOC77_RS07730	COG4862	establishment of competence for transformation
FOC77_RS07735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC77_RS07745	COG1164	Oligoendopeptidase f
FOC77_RS07755	COG2346	COG2346, Truncated hemoglobins
FOC77_RS07760	COG0741	lytic transglycosylase activity
FOC77_RS07765	COG4116	CYTH
FOC77_RS07775	COG2357	RelA SpoT domain protein
FOC77_RS07780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC77_RS07785	COG0564	pseudouridine synthase activity
FOC77_RS07790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC77_RS07795	COG2239	Acts as a magnesium transporter
FOC77_RS07800	COG0569	domain protein
FOC77_RS07800	COG0475	glutathione-regulated potassium exporter activity
FOC77_RS07805	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC77_RS07835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC77_RS07850	COG3344	reverse transcriptase
FOC77_RS07860	COG0210	DNA helicase
FOC77_RS07870	COG2323	membrane
FOC77_RS07875	COG2153	protein acetylation
FOC77_RS07880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC77_RS07885	COG2382	esterase
FOC77_RS07890	COG1328	CTP reductase activity
FOC77_RS07895	COG0602	queuosine metabolic process
FOC77_RS07905	COG0431	NADPH-dependent FMN reductase
FOC77_RS07920	COG0726	polysaccharide deacetylase
FOC77_RS07930	COG0577	efflux transmembrane transporter activity
FOC77_RS07930	COG1136	(ABC) transporter
FOC77_RS07945	COG1737	Transcriptional regulator
FOC77_RS07950	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC77_RS07960	COG1070	Carbohydrate kinase
FOC77_RS07970	COG2169	Transcriptional regulator
FOC77_RS07975	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC77_RS07980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC77_RS07985	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FOC77_RS07990	COG1215	transferase activity, transferring glycosyl groups
FOC77_RS07995	COG1609	Transcriptional regulator
FOC77_RS08000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC77_RS08005	COG0363	glucosamine-6-phosphate deaminase activity
FOC77_RS08010	COG2188	Transcriptional regulator
FOC77_RS08020	COG4585	Histidine kinase
FOC77_RS08025	COG2197	response regulator
FOC77_RS08030	COG2409	Drug exporters of the RND superfamily
FOC77_RS08035	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FOC77_RS08040	COG1595	DNA-templated transcription, initiation
FOC77_RS08045	COG3104	oligopeptide transport
FOC77_RS08060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC77_RS08070	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC77_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS08080	COG3347	Dehydrogenase
FOC77_RS08095	COG1070	Carbohydrate kinase
FOC77_RS08100	COG4806	L-rhamnose isomerase
FOC77_RS08110	COG2972	Histidine kinase
FOC77_RS08115	COG2207	Transcriptional regulator
FOC77_RS08115	COG4753	response regulator
FOC77_RS08130	COG4214	carbohydrate transport
FOC77_RS08135	COG1349	DNA-binding transcription factor activity
FOC77_RS08145	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS08150	COG0366	Alpha amylase catalytic
FOC77_RS08155	COG1263	PTS System
FOC77_RS08155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS08155	COG2190	(PTS) system
FOC77_RS08160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC77_RS08165	COG1442	glycosyl transferase family 8
FOC77_RS08170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC77_RS08195	COG1216	Glycosyl transferase, family 2
FOC77_RS08200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC77_RS08205	COG3541	Predicted nucleotidyltransferase
FOC77_RS08215	COG1834	amidinotransferase
FOC77_RS08220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC77_RS08225	COG1309	transcriptional regulator
FOC77_RS08230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC77_RS08235	COG1523	belongs to the glycosyl hydrolase 13 family
FOC77_RS08250	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC77_RS08255	COG1937	Protein conserved in bacteria
FOC77_RS08260	COG2210	Belongs to the sulfur carrier protein TusA family
FOC77_RS08265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC77_RS08280	COG5577	PFAM Coat F domain
FOC77_RS08290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC77_RS08295	COG3162	membrane
FOC77_RS08300	COG3546	catalase activity
FOC77_RS08305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOC77_RS08335	COG2205	protein histidine kinase activity
FOC77_RS08340	COG0745	RESPONSE REGULATOR receiver
FOC77_RS08355	COG1131	(ABC) transporter
FOC77_RS08380	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC77_RS08385	COG3279	Response regulator of the LytR AlgR family
FOC77_RS08390	COG2972	Histidine kinase
FOC77_RS08400	COG1175	transmembrane transport
FOC77_RS08430	COG2814	Major facilitator Superfamily
FOC77_RS08435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS08440	COG1116	anion transmembrane transporter activity
FOC77_RS08445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC77_RS08450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC77_RS08455	COG0697	spore germination
FOC77_RS08460	COG1609	Transcriptional regulator
FOC77_RS08465	COG4209	transmembrane transport
FOC77_RS08470	COG0395	ABC-type sugar transport system, permease component
FOC77_RS08480	COG1621	beta-fructofuranosidase activity
FOC77_RS08485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS08490	COG1621	beta-fructofuranosidase activity
FOC77_RS08495	COG1621	beta-fructofuranosidase activity
FOC77_RS08500	COG1621	beta-fructofuranosidase activity
FOC77_RS08505	COG1653	transport
FOC77_RS08510	COG4753	response regulator
FOC77_RS08510	COG2207	Transcriptional regulator
FOC77_RS08515	COG2972	Histidine kinase
FOC77_RS08520	COG0583	DNA-binding transcription factor activity
FOC77_RS08525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC77_RS08530	COG2271	Major facilitator Superfamily
FOC77_RS08535	COG0405	Gamma-glutamyltransferase
FOC77_RS08545	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS08555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC77_RS08560	COG2146	nitrite reductase [NAD(P)H] activity
FOC77_RS08565	COG1587	Uroporphyrinogen-III synthase
FOC77_RS08565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC77_RS08575	COG2116	formate transmembrane transporter activity
FOC77_RS08605	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC77_RS08615	COG3588	fructose-bisphosphate aldolase
FOC77_RS08660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC77_RS08670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS08675	COG1349	DNA-binding transcription factor activity
FOC77_RS08680	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS08685	COG3718	enzyme involved in inositol metabolism
FOC77_RS08690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS08695	COG3962	Belongs to the TPP enzyme family
FOC77_RS08700	COG1082	Xylose isomerase domain protein TIM barrel
FOC77_RS08705	COG2814	Major facilitator Superfamily
FOC77_RS08710	COG0673	inositol 2-dehydrogenase activity
FOC77_RS08715	COG1082	Xylose isomerase domain protein TIM barrel
FOC77_RS08720	COG1082	Xylose isomerase domain protein TIM barrel
FOC77_RS08725	COG0191	fructose-bisphosphate aldolase activity
FOC77_RS08730	COG1942	4-Oxalocrotonate Tautomerase
FOC77_RS08755	COG0745	RESPONSE REGULATOR receiver
FOC77_RS08760	COG2205	protein histidine kinase activity
FOC77_RS08775	COG1175	transmembrane transport
FOC77_RS08780	COG0395	ABC-type sugar transport system, permease component
FOC77_RS08790	COG0673	inositol 2-dehydrogenase activity
FOC77_RS08810	COG1082	Xylose isomerase domain protein TIM barrel
FOC77_RS08815	COG3773	Cell wall hydrolase
FOC77_RS08825	COG1136	(ABC) transporter
FOC77_RS08840	COG1732	Glycine betaine
FOC77_RS08850	COG2207	Transcriptional regulator
FOC77_RS08850	COG0662	Cupin 2, conserved barrel domain protein
FOC77_RS08870	COG1874	Beta-galactosidase
FOC77_RS08875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC77_RS08880	COG3773	Cell wall hydrolase
FOC77_RS08890	COG1414	Transcriptional regulator
FOC77_RS08895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC77_RS08900	COG0129	dihydroxy-acid dehydratase activity
FOC77_RS08910	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC77_RS08920	COG0583	DNA-binding transcription factor activity
FOC77_RS08930	COG1811	Na channel or pump
FOC77_RS08940	COG3842	ATPase activity
FOC77_RS08945	COG1175	transmembrane transport
FOC77_RS08960	COG0584	glycerophosphoryl diester phosphodiesterase
FOC77_RS08965	COG0584	glycerophosphoryl diester phosphodiesterase
FOC77_RS08980	COG0142	geranyltranstransferase activity
FOC77_RS08985	COG1234	tRNA 3'-trailer cleavage
FOC77_RS08995	COG0154	amidase activity
FOC77_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS09015	COG2508	Transcriptional regulator
FOC77_RS09020	COG1953	Uracil, thiamine, allantoin
FOC77_RS09040	COG1266	CAAX protease self-immunity
FOC77_RS09050	COG0720	synthase
FOC77_RS09060	COG0302	gtp cyclohydrolase
FOC77_RS09065	COG1595	DNA-templated transcription, initiation
FOC77_RS09080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC77_RS09105	COG0431	NADPH-dependent FMN reductase
FOC77_RS09120	COG0395	ABC-type sugar transport system, permease component
FOC77_RS09125	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC77_RS09130	COG5578	integral membrane protein
FOC77_RS09135	COG3940	Belongs to the glycosyl hydrolase 43 family
FOC77_RS09155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOC77_RS09160	COG2207	Transcriptional regulator
FOC77_RS09165	COG5000	phosphorelay sensor kinase activity
FOC77_RS09170	COG4209	transmembrane transport
FOC77_RS09175	COG0395	ABC-type sugar transport system, permease component
FOC77_RS09180	COG1653	transport
FOC77_RS09185	COG5578	integral membrane protein
FOC77_RS09195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC77_RS09210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC77_RS09215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC77_RS09220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC77_RS09225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC77_RS09230	COG1113	amino acid transport
FOC77_RS09235	COG4555	ABC transporter
FOC77_RS09270	COG3850	Histidine kinase
FOC77_RS09270	COG5002	protein histidine kinase activity
FOC77_RS09280	COG1136	(ABC) transporter
FOC77_RS09295	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS09300	COG1595	DNA-templated transcription, initiation
FOC77_RS09325	COG0366	Alpha amylase catalytic
FOC77_RS09330	COG2017	converts alpha-aldose to the beta-anomer
FOC77_RS09335	COG1175	transmembrane transport
FOC77_RS09340	COG0395	ABC-type sugar transport system, permease component
FOC77_RS09350	COG3254	rhamnose metabolic process
FOC77_RS09355	COG5578	integral membrane protein
FOC77_RS09365	COG2972	Histidine kinase
FOC77_RS09370	COG2207	Transcriptional regulator
FOC77_RS09370	COG4753	response regulator
FOC77_RS09400	COG1266	CAAX protease self-immunity
FOC77_RS09405	COG1404	Belongs to the peptidase S8 family
FOC77_RS09410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC77_RS09425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC77_RS09430	COG2169	Transcriptional regulator
FOC77_RS09440	COG0673	inositol 2-dehydrogenase activity
FOC77_RS09445	COG1082	Xylose isomerase domain protein TIM barrel
FOC77_RS09450	COG0673	inositol 2-dehydrogenase activity
FOC77_RS09455	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC77_RS09480	COG0772	Belongs to the SEDS family
FOC77_RS09490	COG0583	DNA-binding transcription factor activity
FOC77_RS09495	COG1063	alcohol dehydrogenase
FOC77_RS09500	COG2814	Major facilitator Superfamily
FOC77_RS09510	COG1113	amino acid transport
FOC77_RS09520	COG1252	NADH dehydrogenase
FOC77_RS09530	COG0778	Nitroreductase
FOC77_RS09535	COG0252	asparaginase activity
FOC77_RS09540	COG4193	domain, Protein
FOC77_RS09545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC77_RS09550	COG0791	NLP P60 protein
FOC77_RS09550	COG3883	PFAM NLP P60 protein
FOC77_RS09555	COG1121	(ABC) transporter
FOC77_RS09560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC77_RS09575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FOC77_RS09580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS09585	COG1119	ATPase activity
FOC77_RS09590	COG0561	phosphatase activity
FOC77_RS09600	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC77_RS09605	COG2268	Band 7 protein
FOC77_RS09610	COG2113	Glycine betaine
FOC77_RS09615	COG4176	ABC-type proline glycine betaine transport system permease component
FOC77_RS09620	COG0517	IMP dehydrogenase activity
FOC77_RS09620	COG4175	Glycine betaine
FOC77_RS09625	COG1510	regulation of RNA biosynthetic process
FOC77_RS09640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC77_RS09645	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC77_RS09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS09655	COG4597	amino acid ABC transporter
FOC77_RS09660	COG0765	amino acid transport
FOC77_RS09665	COG1126	abc transporter atp-binding protein
FOC77_RS09675	COG0861	Integral membrane protein TerC family
FOC77_RS09685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC77_RS09700	COG3594	Acyltransferase
FOC77_RS09705	COG5002	protein histidine kinase activity
FOC77_RS09715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC77_RS09720	COG0436	Aminotransferase
FOC77_RS09730	COG3852	Histidine kinase
FOC77_RS09735	COG1846	Transcriptional regulator
FOC77_RS09745	COG0542	response to heat
FOC77_RS09750	COG3949	Membrane
FOC77_RS09765	COG4873	Protein conserved in bacteria
FOC77_RS09785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC77_RS09790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC77_RS09795	COG2084	Dehydrogenase
FOC77_RS09800	COG0436	Aminotransferase
FOC77_RS09810	COG1714	RDD family
FOC77_RS09820	COG0784	Response regulator, receiver
FOC77_RS09820	COG0835	chemotaxis
FOC77_RS09830	COG5001	Diguanylate cyclase
FOC77_RS09830	COG3300	MHYT domain
FOC77_RS09835	COG4990	cell redox homeostasis
FOC77_RS09840	COG2200	EAL domain
FOC77_RS09855	COG4703	Protein of unknown function (DUF1797)
FOC77_RS09865	COG0517	IMP dehydrogenase activity
FOC77_RS09870	COG0583	DNA-binding transcription factor activity
FOC77_RS09875	COG2171	N-acyltransferase activity
FOC77_RS09880	COG1473	amidohydrolase
FOC77_RS09890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC77_RS09895	COG0569	domain protein
FOC77_RS09900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC77_RS09925	COG0022	dehydrogenase e1 component
FOC77_RS09930	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC77_RS09950	COG1982	Orn Lys Arg decarboxylase major
FOC77_RS09960	COG4493	Belongs to the UPF0637 family
FOC77_RS09970	COG0483	inositol monophosphate 1-phosphatase activity
FOC77_RS09990	COG4896	Protein conserved in bacteria
FOC77_RS10000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC77_RS10005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC77_RS10015	COG0772	Belongs to the SEDS family
FOC77_RS10030	COG2340	Cysteine-rich secretory protein family
FOC77_RS10050	COG3679	Belongs to the UPF0342 family
FOC77_RS10055	COG4471	UPF0298 protein
FOC77_RS10060	COG0742	ribosomal rna small subunit methyltransferase
FOC77_RS10065	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC77_RS10070	COG3314	Sporulation integral membrane protein YlbJ
FOC77_RS10075	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC77_RS10080	COG1323	Belongs to the UPF0348 family
FOC77_RS10085	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC77_RS10090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC77_RS10095	COG1683	Conserved Protein
FOC77_RS10105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC77_RS10115	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FOC77_RS10120	COG2001	Belongs to the MraZ family
FOC77_RS10145	COG0768	penicillin binding
FOC77_RS10150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC77_RS10160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC77_RS10165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOC77_RS10170	COG0772	Belongs to the SEDS family
FOC77_RS10175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC77_RS10180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC77_RS10185	COG3879	Bacterial protein of unknown function (DUF881)
FOC77_RS10190	COG3879	Bacterial protein of unknown function (DUF881)
FOC77_RS10195	COG3856	small basic protein
FOC77_RS10200	COG0849	cell division
FOC77_RS10205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC77_RS10215	COG1191	sigma factor activity
FOC77_RS10220	COG1191	sigma factor activity
FOC77_RS10230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC77_RS10235	COG1799	cell septum assembly
FOC77_RS10240	COG0762	integral membrane protein
FOC77_RS10245	COG2302	S4 RNA-binding domain
FOC77_RS10250	COG3599	regulation of cell shape
FOC77_RS10255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC77_RS10260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC77_RS10265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC77_RS10270	COG0564	pseudouridine synthase activity
FOC77_RS10275	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FOC77_RS10285	COG0540	Belongs to the ATCase OTCase family
FOC77_RS10290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOC77_RS10310	COG0167	dihydroorotate dehydrogenase activity
FOC77_RS10330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC77_RS10335	COG1561	YicC-like family, N-terminal region
FOC77_RS10345	COG0194	GDP metabolic process
FOC77_RS10355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC77_RS10360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC77_RS10380	COG3833	ABC-type maltose transport systems, permease component
FOC77_RS10390	COG3250	beta-galactosidase activity
FOC77_RS10395	COG3250	beta-galactosidase activity
FOC77_RS10405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC77_RS10410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC77_RS10410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC77_RS10420	COG0631	protein serine/threonine phosphatase activity
FOC77_RS10425	COG0515	serine threonine protein kinase
FOC77_RS10425	COG2815	serine threonine protein kinase
FOC77_RS10430	COG1162	GTPase activity
FOC77_RS10435	COG1564	THIamine pyrophosphokinase
FOC77_RS10445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC77_RS10450	COG1302	Protein conserved in bacteria
FOC77_RS10455	COG1461	Dihydroxyacetone kinase
FOC77_RS10460	COG1760	l-serine dehydratase
FOC77_RS10465	COG1760	l-serine dehydratase
FOC77_RS10470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC77_RS10475	COG1349	DNA-binding transcription factor activity
FOC77_RS10480	COG0416	fatty acid biosynthetic process
FOC77_RS10485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC77_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS10495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC77_RS10500	COG0571	ribonuclease III activity
FOC77_RS10505	COG1196	nuclear chromosome segregation
FOC77_RS10510	COG0552	protein localization to endoplasmic reticulum
FOC77_RS10525	COG1131	(ABC) transporter
FOC77_RS10540	COG0714	Associated with various cellular activities
FOC77_RS10565	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FOC77_RS10570	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC77_RS10580	COG1837	Belongs to the UPF0109 family
FOC77_RS10590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOC77_RS10605	COG0681	Belongs to the peptidase S26 family
FOC77_RS10610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC77_RS10625	COG2257	FlhB HrpN YscU SpaS Family
FOC77_RS10630	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC77_RS10635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC77_RS10640	COG0758	DNA mediated transformation
FOC77_RS10645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC77_RS10650	COG4974	Belongs to the 'phage' integrase family
FOC77_RS10660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOC77_RS10665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FOC77_RS10670	COG1815	bacterial-type flagellum-dependent cell motility
FOC77_RS10675	COG1558	bacterial-type flagellum-dependent cell motility
FOC77_RS10680	COG1677	Flagellar hook-basal body complex protein FliE
FOC77_RS10685	COG1766	The M ring may be actively involved in energy transduction
FOC77_RS10690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC77_RS10695	COG1317	bacterial-type flagellum organization
FOC77_RS10700	COG1157	protein secretion by the type III secretion system
FOC77_RS10705	COG2882	bacterial-type flagellum organization
FOC77_RS10720	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOC77_RS10730	COG4786	Flagellar basal body rod
FOC77_RS10735	COG1582	Flagellar protein (FlbD)
FOC77_RS10740	COG1580	Controls the rotational direction of flagella during chemotaxis
FOC77_RS10745	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC77_RS10750	COG1776	CheC inhibitor of MCP methylation
FOC77_RS10750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC77_RS10755	COG2201	protein-glutamate methylesterase activity
FOC77_RS10760	COG3190	flagellar
FOC77_RS10765	COG1338	Plays a role in the flagellum-specific transport system
FOC77_RS10770	COG1987	bacterial-type flagellum assembly
FOC77_RS10775	COG1684	flagellar biosynthetic protein fliR
FOC77_RS10780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC77_RS10785	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC77_RS10790	COG1419	protein localization to endoplasmic reticulum
FOC77_RS10795	COG0455	bacterial-type flagellum organization
FOC77_RS10800	COG2201	protein-glutamate methylesterase activity
FOC77_RS10805	COG0643	Histidine kinase
FOC77_RS10805	COG2198	Histidine kinase
FOC77_RS10810	COG0835	chemotaxis
FOC77_RS10815	COG1776	CheC inhibitor of MCP methylation
FOC77_RS10820	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FOC77_RS10825	COG1191	sigma factor activity
FOC77_RS10855	COG0233	cytoplasmic translational termination
FOC77_RS10865	COG4589	Belongs to the CDS family
FOC77_RS10875	COG0750	zinc metalloprotease
FOC77_RS10885	COG2176	DNA-directed DNA polymerase activity
FOC77_RS10890	COG0779	Required for maturation of 30S ribosomal subunits
FOC77_RS10895	COG0195	Participates in both transcription termination and antitermination
FOC77_RS10900	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC77_RS10905	COG1358	cellular component organization or biogenesis
FOC77_RS10910	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOC77_RS10915	COG1550	Protein conserved in bacteria
FOC77_RS10925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC77_RS10930	COG0196	riboflavin kinase activity
FOC77_RS10935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOC77_RS10940	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC77_RS10945	COG0726	polysaccharide deacetylase
FOC77_RS10950	COG0612	Peptidase, M16
FOC77_RS10955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC77_RS10960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC77_RS10965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC77_RS10970	COG0527	aspartate kinase activity
FOC77_RS10980	COG1113	amino acid transport
FOC77_RS10985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC77_RS10990	COG0740	serine-type endopeptidase activity
FOC77_RS11005	COG1674	ftsk spoiiie
FOC77_RS11005	COG4980	gas vesicle protein
FOC77_RS11010	COG2188	Transcriptional regulator
FOC77_RS11040	COG0612	Peptidase, M16
FOC77_RS11045	COG0612	Peptidase, M16
FOC77_RS11050	COG0300	oxidoreductase activity
FOC77_RS11065	COG1426	Protein conserved in bacteria
FOC77_RS11070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC77_RS11075	COG1546	Belongs to the CinA family
FOC77_RS11075	COG1058	Belongs to the CinA family
FOC77_RS11080	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOC77_RS11085	COG1418	mRNA catabolic process
FOC77_RS11090	COG1692	metallophosphoesterase
FOC77_RS11095	COG2359	stage V sporulation protein S
FOC77_RS11105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC77_RS11110	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC77_RS11140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC77_RS11145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC77_RS11185	COG2217	Heavy metal translocating P-type atpase
FOC77_RS11195	COG0586	Pfam SNARE associated Golgi protein
FOC77_RS11210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC77_RS11215	COG0601	transmembrane transport
FOC77_RS11225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC77_RS11230	COG2271	Major facilitator Superfamily
FOC77_RS11235	COG1846	Transcriptional regulator
FOC77_RS11235	COG0456	acetyltransferase
FOC77_RS11240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOC77_RS11245	COG0583	DNA-binding transcription factor activity
FOC77_RS11265	COG2318	DinB family
FOC77_RS11270	COG2207	Transcriptional regulator
FOC77_RS11275	COG2323	membrane
FOC77_RS11290	COG1309	transcriptional regulator
FOC77_RS11295	COG2323	membrane
FOC77_RS11305	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC77_RS11305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC77_RS11310	COG0693	protein deglycase activity
FOC77_RS11315	COG2378	regulation of single-species biofilm formation
FOC77_RS11320	COG3773	Cell wall hydrolase
FOC77_RS11350	COG0583	DNA-binding transcription factor activity
FOC77_RS11360	COG0531	amino acid
FOC77_RS11375	COG4977	sequence-specific DNA binding
FOC77_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS11390	COG0640	Transcriptional regulator
FOC77_RS11420	COG1794	racemase activity, acting on amino acids and derivatives
FOC77_RS11425	COG0076	glutamate decarboxylase activity
FOC77_RS11445	COG0768	penicillin binding
FOC77_RS11475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC77_RS11475	COG0723	plastoquinol--plastocyanin reductase activity
FOC77_RS11490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOC77_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS11520	COG2207	Transcriptional regulator
FOC77_RS11520	COG3708	Transcriptional regulator
FOC77_RS11535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC77_RS11565	COG3546	catalase activity
FOC77_RS11590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC77_RS11625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC77_RS11635	COG0217	transcriptional regulatory protein
FOC77_RS11640	COG0789	Transcriptional regulator
FOC77_RS11660	COG1051	belongs to the nudix hydrolase family
FOC77_RS11680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOC77_RS11690	COG0454	-acetyltransferase
FOC77_RS11695	COG2814	Major facilitator Superfamily
FOC77_RS11720	COG2207	Transcriptional regulator
FOC77_RS11720	COG3708	Transcriptional regulator
FOC77_RS11735	COG1733	regulation of RNA biosynthetic process
FOC77_RS11740	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC77_RS11745	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC77_RS11750	COG0697	spore germination
FOC77_RS11755	COG2207	Transcriptional regulator
FOC77_RS11755	COG1917	Cupin 2, conserved barrel domain protein
FOC77_RS11770	COG2318	DinB family
FOC77_RS11785	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC77_RS11805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS11835	COG0640	Transcriptional regulator
FOC77_RS11840	COG2814	Major facilitator Superfamily
FOC77_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS11855	COG1309	transcriptional regulator
FOC77_RS11860	COG2814	Major facilitator Superfamily
FOC77_RS11880	COG5002	protein histidine kinase activity
FOC77_RS11925	COG2267	carboxylic ester hydrolase activity
FOC77_RS11945	COG3708	Transcriptional regulator
FOC77_RS11945	COG2207	Transcriptional regulator
FOC77_RS11955	COG0018	arginyl-trna synthetase
FOC77_RS11960	COG4549	nuclear export factor GLE1
FOC77_RS11990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS12000	COG0592	DNA-directed DNA polymerase activity
FOC77_RS12055	COG4106	trans-aconitate 2-methyltransferase activity
FOC77_RS12075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS12095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC77_RS12100	COG0022	dehydrogenase e1 component
FOC77_RS12105	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC77_RS12110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC77_RS12115	COG0316	Belongs to the HesB IscA family
FOC77_RS12130	COG2264	protein methyltransferase activity
FOC77_RS12140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC77_RS12145	COG3002	Belongs to the UPF0753 family
FOC77_RS12150	COG0288	reversible hydration of carbon dioxide
FOC77_RS12155	COG5609	conserved protein (DUF2294)
FOC77_RS12160	COG2801	Transposase and inactivated derivatives
FOC77_RS12205	COG2076	Multidrug Resistance protein
FOC77_RS12210	COG2076	Multidrug Resistance protein
FOC77_RS12215	COG1309	transcriptional regulator
FOC77_RS12235	COG0412	Dienelactone hydrolase
FOC77_RS12265	COG0583	DNA-binding transcription factor activity
FOC77_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS12300	COG5002	protein histidine kinase activity
FOC77_RS12350	COG2244	polysaccharide biosynthetic process
FOC77_RS12395	COG1846	Transcriptional regulator
FOC77_RS12400	COG0456	acetyltransferase
FOC77_RS12405	COG1104	cysteine desulfurase activity
FOC77_RS12410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC77_RS12415	COG0157	Belongs to the NadC ModD family
FOC77_RS12420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC77_RS12435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC77_RS12450	COG0464	growth
FOC77_RS12455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC77_RS12460	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC77_RS12465	COG0789	Transcriptional regulator
FOC77_RS12470	COG0174	glutamine synthetase
FOC77_RS12490	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC77_RS12570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOC77_RS12580	COG2080	2 iron, 2 sulfur cluster binding
FOC77_RS12595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC77_RS12600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC77_RS12610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC77_RS12615	COG4224	UPF0291 protein
FOC77_RS12630	COG3763	UPF0154 protein
FOC77_RS12660	COG1132	(ABC) transporter
FOC77_RS12665	COG1132	(ABC) transporter
FOC77_RS12675	COG0785	Cytochrome C biogenesis protein
FOC77_RS12680	COG2201	protein-glutamate methylesterase activity
FOC77_RS12685	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC77_RS12720	COG0420	3'-5' exonuclease activity
FOC77_RS12725	COG0419	ATPase involved in DNA repair
FOC77_RS12730	COG1876	peptidase activity
FOC77_RS12735	COG1363	Peptidase, m42
FOC77_RS12740	COG1368	sulfuric ester hydrolase activity
FOC77_RS12745	COG3973	AAA domain
FOC77_RS12750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC77_RS12760	COG3764	Sortase (surface protein transpeptidase)
FOC77_RS12770	COG0456	acetyltransferase
FOC77_RS12775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS12790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC77_RS12800	COG5577	PFAM Coat F domain
FOC77_RS12805	COG1063	alcohol dehydrogenase
FOC77_RS12815	COG5577	PFAM Coat F domain
FOC77_RS12820	COG1609	Transcriptional regulator
FOC77_RS12825	COG1653	transport
FOC77_RS12830	COG1175	transmembrane transport
FOC77_RS12835	COG0395	ABC-type sugar transport system, permease component
FOC77_RS12840	COG1486	melibiose metabolic process
FOC77_RS12860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC77_RS12865	COG1247	-acetyltransferase
FOC77_RS12880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS12890	COG1227	inorganic diphosphatase activity
FOC77_RS12900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC77_RS12915	COG0464	growth
FOC77_RS12935	COG4841	protein insertion into membrane
FOC77_RS12940	COG2843	Capsule synthesis protein
FOC77_RS12945	COG3852	Histidine kinase
FOC77_RS12950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC77_RS12965	COG1960	acyl-CoA dehydrogenase activity
FOC77_RS12975	COG3153	acetyltransferase
FOC77_RS12975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC77_RS12980	COG0456	acetyltransferase
FOC77_RS12985	COG5504	Zn-dependent protease
FOC77_RS12990	COG1846	Transcriptional regulator
FOC77_RS12995	COG0477	Major facilitator Superfamily
FOC77_RS13015	COG0646	methionine synthase
FOC77_RS13015	COG1410	methionine synthase
FOC77_RS13020	COG0646	methionine synthase
FOC77_RS13020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC77_RS13025	COG0626	cystathionine gamma-synthase activity
FOC77_RS13030	COG0626	cystathionine gamma-synthase activity
FOC77_RS13040	COG0745	RESPONSE REGULATOR receiver
FOC77_RS13045	COG5002	protein histidine kinase activity
FOC77_RS13050	COG0567	Dehydrogenase, E1 component
FOC77_RS13055	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC77_RS13070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC77_RS13090	COG1335	isochorismatase
FOC77_RS13095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC77_RS13110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC77_RS13120	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC77_RS13120	COG0392	lysyltransferase activity
FOC77_RS13125	COG1686	Belongs to the peptidase S11 family
FOC77_RS13130	COG0488	(ABC) transporter
FOC77_RS13135	COG2116	formate transmembrane transporter activity
FOC77_RS13160	COG0514	ATP-dependent DNA helicase (RecQ)
FOC77_RS13165	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC77_RS13175	COG5002	protein histidine kinase activity
FOC77_RS13180	COG1388	LysM domain
FOC77_RS13180	COG3584	3D domain protein
FOC77_RS13195	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOC77_RS13205	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FOC77_RS13210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FOC77_RS13215	COG2080	2 iron, 2 sulfur cluster binding
FOC77_RS13220	COG3648	Uricase
FOC77_RS13220	COG3195	allantoin biosynthetic process
FOC77_RS13225	COG2351	hydroxyisourate hydrolase activity
FOC77_RS13230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOC77_RS13240	COG2223	nitrite transmembrane transporter activity
FOC77_RS13255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC77_RS13265	COG0561	phosphatase activity
FOC77_RS13275	COG1164	Oligoendopeptidase f
FOC77_RS13280	COG0583	DNA-binding transcription factor activity
FOC77_RS13285	COG0067	glutamate synthase
FOC77_RS13285	COG0069	glutamate synthase activity
FOC77_RS13285	COG0070	glutamate synthase
FOC77_RS13290	COG0493	'glutamate synthase
FOC77_RS13295	COG1418	mRNA catabolic process
FOC77_RS13305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC77_RS13310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC77_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS13320	COG0861	Integral membrane protein TerC family
FOC77_RS13325	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC77_RS13350	COG1725	Transcriptional regulator
FOC77_RS13365	COG4974	Belongs to the 'phage' integrase family
FOC77_RS13380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOC77_RS13385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC77_RS13385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC77_RS13390	COG0307	riboflavin synthase, alpha
FOC77_RS13395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC77_RS13400	COG0708	Exodeoxyribonuclease III
FOC77_RS13405	COG0346	lactoylglutathione lyase activity
FOC77_RS13410	COG0561	phosphatase activity
FOC77_RS13430	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS13450	COG2205	protein histidine kinase activity
FOC77_RS13455	COG1136	(ABC) transporter
FOC77_RS13460	COG0577	efflux transmembrane transporter activity
FOC77_RS13470	COG1309	transcriptional regulator
FOC77_RS13490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC77_RS13490	COG0456	acetyltransferase
FOC77_RS13500	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC77_RS13510	COG0328	RNA-DNA hybrid ribonuclease activity
FOC77_RS13510	COG3341	Caulimovirus viroplasmin
FOC77_RS13515	COG3275	phosphorelay sensor kinase activity
FOC77_RS13520	COG3279	Response regulator of the LytR AlgR family
FOC77_RS13525	COG1966	Carbon starvation protein
FOC77_RS13535	COG2066	Belongs to the glutaminase family
FOC77_RS13540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC77_RS13550	COG0582	viral genome integration into host DNA
FOC77_RS13555	COG1395	domain, Protein
FOC77_RS13575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC77_RS13705	COG2002	toxin-antitoxin pair type II binding
FOC77_RS13710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC77_RS13815	COG5484	DNA packaging
FOC77_RS13815	COG3728	DNA packaging
FOC77_RS13935	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC77_RS13995	COG1280	lysine exporter protein (LysE YggA)
FOC77_RS14000	COG0024	Methionine aminopeptidase
FOC77_RS14010	COG0531	amino acid
FOC77_RS14030	COG1042	CoA-binding domain protein
FOC77_RS14030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC77_RS14030	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC77_RS14035	COG0753	catalase activity
FOC77_RS14040	COG0326	Molecular chaperone. Has ATPase activity
FOC77_RS14045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC77_RS14050	COG1280	lysine exporter protein (LysE YggA)
FOC77_RS14095	COG3689	TIGRFAM TIGR03943 family protein
FOC77_RS14100	COG0701	Predicted permease
FOC77_RS14105	COG0726	polysaccharide deacetylase
FOC77_RS14115	COG0492	ferredoxin-NADP+ reductase activity
FOC77_RS14120	COG1609	Transcriptional regulator
FOC77_RS14125	COG1621	beta-fructofuranosidase activity
FOC77_RS14140	COG0583	DNA-binding transcription factor activity
FOC77_RS14160	COG1349	DNA-binding transcription factor activity
FOC77_RS14165	COG4977	sequence-specific DNA binding
FOC77_RS14180	COG1051	belongs to the nudix hydrolase family
FOC77_RS14185	COG4473	ABC transporter
FOC77_RS14190	COG1131	(ABC) transporter
FOC77_RS14195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC77_RS14220	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC77_RS14240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC77_RS14245	COG0187	DNA topoisomerase II activity
FOC77_RS14250	COG1832	CoA-binding protein
FOC77_RS14255	COG0840	transmembrane signaling receptor activity
FOC77_RS14260	COG3858	chitin binding
FOC77_RS14270	COG3859	Proton-coupled thiamine transporter YuaJ
FOC77_RS14280	COG1309	transcriptional regulator
FOC77_RS14295	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC77_RS14300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC77_RS14305	COG0204	Acyl-transferase
FOC77_RS14310	COG0561	phosphatase activity
FOC77_RS14315	COG1349	DNA-binding transcription factor activity
FOC77_RS14320	COG2267	carboxylic ester hydrolase activity
FOC77_RS14330	COG1482	cell wall glycoprotein biosynthetic process
FOC77_RS14335	COG1404	Belongs to the peptidase S8 family
FOC77_RS14340	COG2814	Major facilitator Superfamily
FOC77_RS14365	COG1268	BioY protein
FOC77_RS14370	COG1276	copper resistance
FOC77_RS14370	COG2372	response to copper ion
FOC77_RS14390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC77_RS14395	COG0737	Belongs to the 5'-nucleotidase family
FOC77_RS14405	COG0561	phosphatase activity
FOC77_RS14415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC77_RS14420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOC77_RS14435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS14445	COG1011	Hydrolase
FOC77_RS14450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC77_RS14480	COG1695	Transcriptional regulator
FOC77_RS14490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC77_RS14495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC77_RS14500	COG0561	phosphatase activity
FOC77_RS14505	COG0697	spore germination
FOC77_RS14510	COG1132	(ABC) transporter
FOC77_RS14515	COG0583	DNA-binding transcription factor activity
FOC77_RS14540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC77_RS14545	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC77_RS14550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC77_RS14560	COG2814	Major facilitator Superfamily
FOC77_RS14565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS14565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS14565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS14570	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC77_RS14575	COG1349	DNA-binding transcription factor activity
FOC77_RS14590	COG2176	DNA-directed DNA polymerase activity
FOC77_RS14600	COG0004	ammonium transporteR
FOC77_RS14615	COG0351	phosphomethylpyrimidine kinase
FOC77_RS14630	COG0701	Predicted permease
FOC77_RS14635	COG0523	cobalamin synthesis protein
FOC77_RS14640	COG0840	transmembrane signaling receptor activity
FOC77_RS14650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC77_RS14695	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOC77_RS14700	COG1737	Transcriptional regulator
FOC77_RS14705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS14705	COG1263	PTS System
FOC77_RS14720	COG1609	Transcriptional regulator
FOC77_RS14730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC77_RS14735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC77_RS14740	COG0523	cobalamin synthesis protein
FOC77_RS14785	COG2849	repeat protein
FOC77_RS14840	COG3739	integral membrane protein
FOC77_RS14845	COG3655	Transcriptional regulator
FOC77_RS14865	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FOC77_RS14870	COG5646	InterPro IPR014922
FOC77_RS14900	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC77_RS14920	COG0494	nUDIX hydrolase
FOC77_RS14925	COG2155	Conserved Protein
FOC77_RS14930	COG2733	membrane
FOC77_RS14950	COG0384	phenazine biosynthesis protein PhzF
FOC77_RS14970	COG1690	Belongs to the RtcB family
FOC77_RS14975	COG4377	Putative membrane peptidase family (DUF2324)
FOC77_RS14990	COG0586	Pfam SNARE associated Golgi protein
FOC77_RS15010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC77_RS15020	COG0406	alpha-ribazole phosphatase activity
FOC77_RS15025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC77_RS15075	COG0726	polysaccharide deacetylase
FOC77_RS15100	COG0583	DNA-binding transcription factor activity
FOC77_RS15110	COG1346	cytolysis
FOC77_RS15135	COG0513	Belongs to the DEAD box helicase family
FOC77_RS15145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC77_RS15150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC77_RS15160	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC77_RS15165	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC77_RS15170	COG0671	phosphoesterase, PA-phosphatase related
FOC77_RS15175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOC77_RS15180	COG1793	dna ligase
FOC77_RS15180	COG3285	dna ligase
FOC77_RS15190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOC77_RS15195	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOC77_RS15225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC77_RS15230	COG0640	Transcriptional regulator
FOC77_RS15235	COG0534	Mate efflux family protein
FOC77_RS15255	COG2340	Cysteine-rich secretory protein family
FOC77_RS15270	COG0523	cobalamin synthesis protein
FOC77_RS15275	COG0793	Belongs to the peptidase S41A family
FOC77_RS15275	COG3409	Peptidoglycan-binding domain 1 protein
FOC77_RS15280	COG1876	peptidase activity
FOC77_RS15310	COG4479	Belongs to the UPF0346 family
FOC77_RS15320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC77_RS15345	COG2755	lipolytic protein G-D-S-L family
FOC77_RS15350	COG5002	protein histidine kinase activity
FOC77_RS15360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC77_RS15365	COG1272	protein, Hemolysin III
FOC77_RS15370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC77_RS15375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOC77_RS15385	COG2310	stress, protein
FOC77_RS15390	COG2310	stress, protein
FOC77_RS15395	COG3853	Toxic anion resistance protein (TelA)
FOC77_RS15410	COG1358	cellular component organization or biogenesis
FOC77_RS15425	COG0861	Integral membrane protein TerC family
FOC77_RS15430	COG2310	stress, protein
FOC77_RS15440	COG2136	Putative SAM-dependent methyltransferase
FOC77_RS15440	COG2521	methyltransferase
FOC77_RS15450	COG1413	lyase activity
FOC77_RS15455	COG0488	(ABC) transporter
FOC77_RS15460	COG1418	mRNA catabolic process
FOC77_RS15480	COG0386	Belongs to the glutathione peroxidase family
FOC77_RS15490	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOC77_RS15495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOC77_RS15510	COG1321	iron dependent repressor
FOC77_RS15515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC77_RS15515	COG0551	DNA topoisomerase type I activity
FOC77_RS15520	COG4129	membrane
FOC77_RS15535	COG1278	Cold shock
FOC77_RS15545	COG0328	RNA-DNA hybrid ribonuclease activity
FOC77_RS15550	COG0328	RNA-DNA hybrid ribonuclease activity
FOC77_RS15560	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC77_RS15570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC77_RS15580	COG1131	(ABC) transporter
FOC77_RS15595	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC77_RS15610	COG1199	ATP-dependent helicase activity
FOC77_RS15620	COG0116	Belongs to the methyltransferase superfamily
FOC77_RS15635	COG4474	Belongs to the UPF0398 family
FOC77_RS15645	COG3359	exonuclease
FOC77_RS15650	COG1111	helicase
FOC77_RS15650	COG1205	dead DEAH box helicase
FOC77_RS15655	COG2267	carboxylic ester hydrolase activity
FOC77_RS15660	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC77_RS15690	COG3331	DNA recombination
FOC77_RS15695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC77_RS15695	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC77_RS15705	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC77_RS15710	COG3935	DnaD domain protein
FOC77_RS15715	COG0017	Asparaginyl-tRNA synthetase
FOC77_RS15720	COG0436	Aminotransferase
FOC77_RS15730	COG1199	ATP-dependent helicase activity
FOC77_RS15730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC77_RS15735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC77_RS15740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC77_RS15745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC77_RS15755	COG0617	tRNA 3'-terminal CCA addition
FOC77_RS15760	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS15765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC77_RS15770	COG1803	Methylglyoxal synthase
FOC77_RS15775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOC77_RS15780	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC77_RS15785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS15795	COG2223	nitrite transmembrane transporter activity
FOC77_RS15800	COG2738	Putative neutral zinc metallopeptidase
FOC77_RS15810	COG4347	Protein of unknown function (DUF1405)
FOC77_RS15815	COG5582	Belongs to the UPF0302 family
FOC77_RS15820	COG0457	Tetratricopeptide repeat
FOC77_RS15830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC77_RS15835	COG0287	Prephenate dehydrogenase
FOC77_RS15840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC77_RS15845	COG4401	Chorismate mutase type I
FOC77_RS15850	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOC77_RS15855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC77_RS15860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC77_RS15865	COG0105	UTP biosynthetic process
FOC77_RS15870	COG0142	geranyltranstransferase activity
FOC77_RS15875	COG2226	methyltransferase
FOC77_RS15880	COG0142	geranyltranstransferase activity
FOC77_RS15885	COG0776	regulation of translation
FOC77_RS15890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC77_RS15895	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC77_RS15900	COG1160	GTP binding
FOC77_RS15925	COG0539	negative regulation of cytoplasmic translation
FOC77_RS15945	COG2959	enzyme of heme biosynthesis
FOC77_RS15950	COG3409	Peptidoglycan-binding domain 1 protein
FOC77_RS15950	COG3773	Cell wall hydrolase
FOC77_RS15955	COG2339	peptidase activity
FOC77_RS15960	COG0492	ferredoxin-NADP+ reductase activity
FOC77_RS15965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC77_RS15970	COG4862	establishment of competence for transformation
FOC77_RS15975	COG1408	metallophosphoesterase
FOC77_RS15990	COG3546	catalase activity
FOC77_RS16005	COG1266	CAAX protease self-immunity
FOC77_RS16010	COG0514	ATP-dependent DNA helicase (RecQ)
FOC77_RS16015	COG4955	Helix-turn-helix domain
FOC77_RS16020	COG1141	Ferredoxin
FOC77_RS16030	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC77_RS16035	COG0739	heme binding
FOC77_RS16050	COG1595	DNA-templated transcription, initiation
FOC77_RS16055	COG5002	protein histidine kinase activity
FOC77_RS16060	COG0745	RESPONSE REGULATOR receiver
FOC77_RS16065	COG1187	pseudouridine synthase activity
FOC77_RS16070	COG0700	Nucleoside recognition
FOC77_RS16075	COG2715	membrane protein required for spore maturation
FOC77_RS16080	COG1686	Belongs to the peptidase S11 family
FOC77_RS16085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC77_RS16090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOC77_RS16095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOC77_RS16100	COG1547	Domain of unknown function (DUF309)
FOC77_RS16110	COG4086	secreted protein
FOC77_RS16120	COG0697	spore germination
FOC77_RS16145	COG2172	sigma factor antagonist activity
FOC77_RS16155	COG1686	Belongs to the peptidase S11 family
FOC77_RS16160	COG0024	Methionine aminopeptidase
FOC77_RS16165	COG1595	DNA-templated transcription, initiation
FOC77_RS16185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC77_RS16190	COG4974	Belongs to the 'phage' integrase family
FOC77_RS16200	COG0735	belongs to the Fur family
FOC77_RS16205	COG1300	Membrane
FOC77_RS16215	COG1379	DNA repair
FOC77_RS16230	COG0667	Aldo Keto reductase
FOC77_RS16245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS16250	COG0456	acetyltransferase
FOC77_RS16260	COG1078	dGTPase activity
FOC77_RS16310	COG1595	DNA-templated transcription, initiation
FOC77_RS16340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS16345	COG3620	sequence-specific DNA binding
FOC77_RS16375	COG1764	response to oxidative stress
FOC77_RS16380	COG1073	alpha beta
FOC77_RS16410	COG5566	PFAM Mor transcription activator
FOC77_RS16420	COG0840	transmembrane signaling receptor activity
FOC77_RS16425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC77_RS16430	COG2814	Major facilitator Superfamily
FOC77_RS16435	COG1846	Transcriptional regulator
FOC77_RS16445	COG0300	oxidoreductase activity
FOC77_RS16455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC77_RS16460	COG1234	tRNA 3'-trailer cleavage
FOC77_RS16465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC77_RS16470	COG1408	metallophosphoesterase
FOC77_RS16480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC77_RS16485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC77_RS16495	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC77_RS16505	COG1376	ErfK ybiS ycfS ynhG family protein
FOC77_RS16510	COG1126	abc transporter atp-binding protein
FOC77_RS16515	COG0765	amino acid transport
FOC77_RS16520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS16530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC77_RS16535	COG0022	dehydrogenase e1 component
FOC77_RS16540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC77_RS16545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC77_RS16550	COG3426	butyrate kinase activity
FOC77_RS16555	COG3290	protein histidine kinase activity
FOC77_RS16555	COG3829	transcription factor binding
FOC77_RS16560	COG0584	glycerophosphoryl diester phosphodiesterase
FOC77_RS16610	COG0745	RESPONSE REGULATOR receiver
FOC77_RS16615	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC77_RS16620	COG0750	zinc metalloprotease
FOC77_RS16625	COG0497	DNA recombination
FOC77_RS16630	COG1438	arginine binding
FOC77_RS16635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC77_RS16640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC77_RS16645	COG0142	geranyltranstransferase activity
FOC77_RS16650	COG1722	exodeoxyribonuclease VII activity
FOC77_RS16665	COG1302	Protein conserved in bacteria
FOC77_RS16670	COG0439	Biotin carboxylase
FOC77_RS16675	COG0511	ligase activity, forming carbon-carbon bonds
FOC77_RS16715	COG3854	ATPases associated with a variety of cellular activities
FOC77_RS16720	COG1785	Belongs to the alkaline phosphatase family
FOC77_RS16730	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS16735	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC77_RS16740	COG1940	carbohydrate kinase activity
FOC77_RS16750	COG0395	ABC-type sugar transport system, permease component
FOC77_RS16755	COG4209	transmembrane transport
FOC77_RS16770	COG2207	Transcriptional regulator
FOC77_RS16770	COG4753	response regulator
FOC77_RS16775	COG2972	Histidine kinase
FOC77_RS16790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC77_RS16795	COG0006	proline dipeptidase activity
FOC77_RS16805	COG3872	metal-dependent enzyme
FOC77_RS16815	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC77_RS16850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC77_RS16855	COG0095	Lipoate-protein ligase
FOC77_RS16860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC77_RS16865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC77_RS16870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC77_RS16875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC77_RS16880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC77_RS16915	COG4537	Required for transformation and DNA binding
FOC77_RS16920	COG1459	type II secretion system
FOC77_RS16925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC77_RS16940	COG2072	flavoprotein involved in K transport
FOC77_RS16950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC77_RS16955	COG0011	TIGRFAM Protein of
FOC77_RS16970	COG1368	sulfuric ester hydrolase activity
FOC77_RS16975	COG1940	carbohydrate kinase activity
FOC77_RS16990	COG0457	Tetratricopeptide repeat
FOC77_RS16990	COG0705	Rhomboid family
FOC77_RS17010	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC77_RS17015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC77_RS17045	COG0704	Plays a role in the regulation of phosphate uptake
FOC77_RS17050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC77_RS17055	COG0581	inorganic phosphate transmembrane transporter activity
FOC77_RS17060	COG0573	inorganic phosphate transmembrane transporter activity
FOC77_RS17065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC77_RS17080	COG0477	Major facilitator Superfamily
FOC77_RS17090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC77_RS17095	COG2839	Protein conserved in bacteria
FOC77_RS17100	COG5521	maltodextrose utilization protein MalA
FOC77_RS17105	COG0840	transmembrane signaling receptor activity
FOC77_RS17115	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FOC77_RS17125	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FOC77_RS17130	COG0735	belongs to the Fur family
FOC77_RS17140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOC77_RS17145	COG0513	Belongs to the DEAD box helicase family
FOC77_RS17155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC77_RS17160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC77_RS17165	COG2384	SAM-dependent methyltransferase
FOC77_RS17175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC77_RS17180	COG0358	DNA primase activity
FOC77_RS17185	COG1671	Belongs to the UPF0178 family
FOC77_RS17195	COG0517	IMP dehydrogenase activity
FOC77_RS17200	COG0751	glycine-tRNA ligase activity
FOC77_RS17210	COG1381	Involved in DNA repair and RecF pathway recombination
FOC77_RS17220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC77_RS17230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC77_RS17240	COG1480	7TM receptor with intracellular HD hydrolase
FOC77_RS17245	COG1702	phosphate starvation-inducible protein PhoH
FOC77_RS17265	COG4864	UPF0365 protein
FOC77_RS17270	COG1030	water channel activity
FOC77_RS17275	COG1610	YqeY-like protein
FOC77_RS17285	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC77_RS17290	COG1132	(ABC) transporter
FOC77_RS17295	COG1132	(ABC) transporter
FOC77_RS17300	COG2207	Transcriptional regulator
FOC77_RS17300	COG1917	Cupin 2, conserved barrel domain protein
FOC77_RS17305	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC77_RS17310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC77_RS17315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC77_RS17320	COG2264	protein methyltransferase activity
FOC77_RS17330	COG0443	Heat shock 70 kDa protein
FOC77_RS17335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC77_RS17340	COG1420	regulation of RNA biosynthetic process
FOC77_RS17345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC77_RS17350	COG0481	GTPase activity
FOC77_RS17360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FOC77_RS17365	COG0268	Binds directly to 16S ribosomal RNA
FOC77_RS17370	COG1466	dna polymerase III delta subunit
FOC77_RS17375	COG0658	competence protein
FOC77_RS17375	COG2333	competence protein COMEC
FOC77_RS17380	COG2131	deaminase
FOC77_RS17385	COG1555	photosystem II stabilization
FOC77_RS17385	COG1596	polysaccharide export
FOC77_RS17390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC77_RS17395	COG2226	methyltransferase
FOC77_RS17400	COG0799	negative regulation of ribosome biogenesis
FOC77_RS17405	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC77_RS17415	COG1534	Rna-binding protein
FOC77_RS17425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC77_RS17430	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC77_RS17440	COG0688	phosphatidylethanolamine metabolic process
FOC77_RS17445	COG1183	phosphatidylcholine synthase activity
FOC77_RS17460	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC77_RS17480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC77_RS17550	COG4824	toxin secretion phage lysis holin
FOC77_RS17645	COG5484	DNA packaging
FOC77_RS17645	COG3728	DNA packaging
FOC77_RS17655	COG3677	Transposase
FOC77_RS17745	COG3723	Recombinational DNA repair protein, rece pathway
FOC77_RS17750	COG5377	YqaJ viral recombinase family
FOC77_RS17790	COG1396	sequence-specific DNA binding
FOC77_RS17820	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FOC77_RS17840	COG0662	Cupin 2, conserved barrel domain protein
FOC77_RS17850	COG0789	Transcriptional regulator
FOC77_RS17855	COG0673	inositol 2-dehydrogenase activity
FOC77_RS17865	COG0673	inositol 2-dehydrogenase activity
FOC77_RS17870	COG4977	sequence-specific DNA binding
FOC77_RS17875	COG0572	uridine kinase
FOC77_RS17885	COG0626	cystathionine gamma-synthase activity
FOC77_RS17890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC77_RS17895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC77_RS17900	COG2226	methyltransferase
FOC77_RS17915	COG0768	penicillin binding
FOC77_RS17920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC77_RS17925	COG0572	uridine kinase
FOC77_RS17940	COG4122	O-methyltransferase activity
FOC77_RS17945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC77_RS17950	COG3906	Belongs to the UPF0473 family
FOC77_RS17960	COG4472	Bacterial protein of unknown function (DUF965)
FOC77_RS17970	COG0628	permease
FOC77_RS17985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC77_RS18000	COG1104	cysteine desulfurase activity
FOC77_RS18005	COG1959	2 iron, 2 sulfur cluster binding
FOC77_RS18010	COG2364	Membrane
FOC77_RS18015	COG1473	amidohydrolase
FOC77_RS18025	COG4948	Mandelate Racemase Muconate Lactonizing
FOC77_RS18040	COG3833	ABC-type maltose transport systems, permease component
FOC77_RS18055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC77_RS18060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC77_RS18065	COG1131	(ABC) transporter
FOC77_RS18070	COG1131	(ABC) transporter
FOC77_RS18075	COG1725	Transcriptional regulator
FOC77_RS18085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC77_RS18090	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC77_RS18095	COG0124	histidyl-tRNA synthetase
FOC77_RS18105	COG3103	Sh3 type 3 domain protein
FOC77_RS18105	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC77_RS18105	COG4991	sh3 domain protein
FOC77_RS18115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC77_RS18120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC77_RS18125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC77_RS18125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC77_RS18130	COG5416	Lipopolysaccharide assembly protein A domain
FOC77_RS18135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC77_RS18135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC77_RS18145	COG2244	polysaccharide biosynthetic process
FOC77_RS18150	COG2323	membrane
FOC77_RS18160	COG1862	Preprotein translocase
FOC77_RS18170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC77_RS18185	COG0632	four-way junction helicase activity
FOC77_RS18215	COG1827	regulation of RNA biosynthetic process
FOC77_RS18220	COG0077	Prephenate dehydratase
FOC77_RS18225	COG4492	Belongs to the UPF0735 family
FOC77_RS18230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC77_RS18235	COG3290	protein histidine kinase activity
FOC77_RS18240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOC77_RS18245	COG2868	ribosomal protein
FOC77_RS18250	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOC77_RS18255	COG1530	ribonuclease E activity
FOC77_RS18260	COG1994	Peptidase M50
FOC77_RS18265	COG0739	heme binding
FOC77_RS18270	COG2894	cell division
FOC77_RS18275	COG0850	regulation of cytokinetic process
FOC77_RS18280	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOC77_RS18285	COG1792	Involved in formation and maintenance of cell shape
FOC77_RS18290	COG1077	Cell shape determining protein MreB Mrl
FOC77_RS18295	COG2003	Belongs to the UPF0758 family
FOC77_RS18300	COG0424	maF-like protein
FOC77_RS18310	COG4968	Prepilin-type N-terminal cleavage methylation domain
FOC77_RS18330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC77_RS18395	COG3706	GGDEF domain
FOC77_RS18400	COG0285	dihydrofolate synthase activity
FOC77_RS18405	COG0525	valine-tRNA ligase activity
FOC77_RS18410	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC77_RS18415	COG1388	LysM domain
FOC77_RS18415	COG1388	LysM domain
FOC77_RS18420	COG0726	polysaccharide deacetylase
FOC77_RS18430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC77_RS18440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOC77_RS18445	COG0113	porphobilinogen synthase activity
FOC77_RS18455	COG0181	hydroxymethylbilane synthase activity
FOC77_RS18460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC77_RS18475	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC77_RS18480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC77_RS18485	COG0470	DNA polymerase III
FOC77_RS18485	COG1067	ATP-dependent peptidase activity
FOC77_RS18495	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC77_RS18505	COG0066	3-isopropylmalate dehydratase activity
FOC77_RS18510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC77_RS18520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC77_RS18525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC77_RS18530	COG0440	acetolactate synthase activity
FOC77_RS18535	COG0028	Belongs to the TPP enzyme family
FOC77_RS18545	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FOC77_RS18560	COG0622	Phosphoesterase
FOC77_RS18575	COG5401	PFAM Sporulation and spore germination
FOC77_RS18580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC77_RS18585	COG1846	Transcriptional regulator
FOC77_RS18590	COG2197	response regulator
FOC77_RS18600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC77_RS18605	COG1053	succinate dehydrogenase
FOC77_RS18610	COG2009	succinate dehydrogenase
FOC77_RS18615	COG1719	4-vinyl reductase, 4VR
FOC77_RS18630	COG3118	belongs to the thioredoxin family
FOC77_RS18635	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC77_RS18640	COG2086	electron transfer activity
FOC77_RS18645	COG0318	PFAM AMP-dependent synthetase and ligase
FOC77_RS18650	COG3766	membrane
FOC77_RS18655	COG1193	negative regulation of DNA recombination
FOC77_RS18660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC77_RS18660	COG1796	DNA polymerase
FOC77_RS18670	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FOC77_RS18675	COG1940	carbohydrate kinase activity
FOC77_RS18685	COG0395	ABC-type sugar transport system, permease component
FOC77_RS18690	COG1175	transmembrane transport
FOC77_RS18700	COG0072	phenylalanine-tRNA ligase activity
FOC77_RS18700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC77_RS18705	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOC77_RS18710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC77_RS18720	COG1070	Carbohydrate kinase
FOC77_RS18725	COG2115	Belongs to the xylose isomerase family
FOC77_RS18730	COG1940	carbohydrate kinase activity
FOC77_RS18735	COG0628	permease
FOC77_RS18740	COG1363	Peptidase, m42
FOC77_RS18755	COG3326	Membrane
FOC77_RS18760	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOC77_RS18770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC77_RS18775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC77_RS18785	COG1484	DNA-dependent DNA replication
FOC77_RS18790	COG3611	Membrane attachment protein
FOC77_RS18795	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC77_RS18805	COG1971	Probably functions as a manganese efflux pump
FOC77_RS18810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC77_RS18815	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC77_RS18815	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC77_RS18820	COG5002	protein histidine kinase activity
FOC77_RS18825	COG0745	RESPONSE REGULATOR receiver
FOC77_RS18835	COG0538	isocitrate dehydrogenase activity
FOC77_RS18840	COG0372	Belongs to the citrate synthase family
FOC77_RS18845	COG2707	UPF0756 membrane protein
FOC77_RS18850	COG0628	permease
FOC77_RS18855	COG0667	Aldo Keto reductase
FOC77_RS18865	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC77_RS18870	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS18885	COG0395	ABC-type sugar transport system, permease component
FOC77_RS18890	COG4209	transmembrane transport
FOC77_RS18895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC77_RS18900	COG5578	integral membrane protein
FOC77_RS18905	COG0395	ABC-type sugar transport system, permease component
FOC77_RS18910	COG1175	transmembrane transport
FOC77_RS18915	COG1653	transport
FOC77_RS18920	COG2207	Transcriptional regulator
FOC77_RS18925	COG2972	Histidine kinase
FOC77_RS18930	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC77_RS18945	COG0825	malonyl-CoA metabolic process
FOC77_RS18950	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOC77_RS18955	COG2186	Transcriptional regulator
FOC77_RS18960	COG0587	DNA-directed DNA polymerase activity
FOC77_RS18975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC77_RS18980	COG4109	DRTGG domain
FOC77_RS18990	COG0006	proline dipeptidase activity
FOC77_RS19005	COG0589	response to stress
FOC77_RS19010	COG0165	Argininosuccinate lyase
FOC77_RS19015	COG0137	argininosuccinate synthase activity
FOC77_RS19020	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC77_RS19025	COG3973	AAA domain
FOC77_RS19040	COG0827	DNA restriction-modification system
FOC77_RS19045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC77_RS19050	COG3874	Sporulation protein YtfJ
FOC77_RS19060	COG1714	RDD family
FOC77_RS19065	COG0616	signal peptide processing
FOC77_RS19070	COG2962	Rard protein
FOC77_RS19075	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC77_RS19080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC77_RS19090	COG0301	tRNA thio-modification
FOC77_RS19095	COG1104	cysteine desulfurase activity
FOC77_RS19100	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FOC77_RS19105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC77_RS19110	COG1309	transcriptional regulator
FOC77_RS19115	COG1956	GAF domain-containing protein
FOC77_RS19120	COG2199	diguanylate cyclase activity
FOC77_RS19120	COG2203	Gaf domain
FOC77_RS19125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC77_RS19150	COG1605	Chorismate mutase
FOC77_RS19150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC77_RS19160	COG3118	belongs to the thioredoxin family
FOC77_RS19165	COG4980	gas vesicle protein
FOC77_RS19175	COG2309	aminopeptidase activity
FOC77_RS19185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC77_RS19190	COG1674	ftsk spoiiie
FOC77_RS19195	COG4848	Belongs to the UPF0354 family
FOC77_RS19200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC77_RS19205	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC77_RS19210	COG1363	Peptidase, m42
FOC77_RS19215	COG5584	Small secreted protein
FOC77_RS19220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC77_RS19230	COG0510	thiamine kinase activity
FOC77_RS19235	COG1523	belongs to the glycosyl hydrolase 13 family
FOC77_RS19245	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC77_RS19255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC77_RS19265	COG1349	DNA-binding transcription factor activity
FOC77_RS19270	COG1187	pseudouridine synthase activity
FOC77_RS19275	COG2244	polysaccharide biosynthetic process
FOC77_RS19280	COG2081	HI0933 family
FOC77_RS19290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC77_RS19295	COG0495	leucyl-tRNA aminoacylation
FOC77_RS19305	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FOC77_RS19310	COG0154	amidase activity
FOC77_RS19315	COG0406	alpha-ribazole phosphatase activity
FOC77_RS19320	COG2814	Major facilitator Superfamily
FOC77_RS19335	COG1242	4 iron, 4 sulfur cluster binding
FOC77_RS19340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC77_RS19350	COG2267	carboxylic ester hydrolase activity
FOC77_RS19355	COG4990	cell redox homeostasis
FOC77_RS19360	COG0367	asparagine synthase
FOC77_RS19365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC77_RS19375	COG1506	peptidase
FOC77_RS19395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC77_RS19405	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOC77_RS19410	COG0288	reversible hydration of carbon dioxide
FOC77_RS19425	COG0318	PFAM AMP-dependent synthetase and ligase
FOC77_RS19430	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC77_RS19435	COG0596	Alpha beta hydrolase
FOC77_RS19440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC77_RS19445	COG1169	isochorismate synthase
FOC77_RS19450	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC77_RS19455	COG0058	SHG alpha-glucan phosphorylase activity
FOC77_RS19460	COG0297	glycogen (starch) synthase activity
FOC77_RS19465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC77_RS19470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC77_RS19605	COG1285	pathogenesis
FOC77_RS19625	COG3852	Histidine kinase
FOC77_RS19640	COG0604	alcohol dehydrogenase
FOC77_RS19645	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS19650	COG0778	Nitroreductase
FOC77_RS19660	COG3729	General stress protein
FOC77_RS19680	COG2059	Chromate
FOC77_RS19685	COG2059	Chromate
FOC77_RS19695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC77_RS19695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC77_RS19700	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC77_RS19700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC77_RS19705	COG1309	transcriptional regulator
FOC77_RS19710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC77_RS19725	COG1979	alcohol dehydrogenase
FOC77_RS19730	COG2155	Conserved Protein
FOC77_RS19735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC77_RS19740	COG1098	S1 RNA binding domain
FOC77_RS19745	COG0436	Aminotransferase
FOC77_RS19750	COG1522	sequence-specific DNA binding
FOC77_RS19760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC77_RS19765	COG2011	ABC-type metal ion transport system permease component
FOC77_RS19770	COG1464	Belongs to the NlpA lipoprotein family
FOC77_RS19780	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC77_RS19785	COG2032	superoxide dismutase activity
FOC77_RS19795	COG5018	Exonuclease
FOC77_RS19805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC77_RS19805	COG2111	Na H antiporter
FOC77_RS19810	COG2111	Na H antiporter
FOC77_RS19815	COG1006	Multisubunit Na H antiporter MnhC subunit
FOC77_RS19820	COG0651	ATP synthesis coupled electron transport
FOC77_RS19825	COG1863	multisubunit Na H antiporter MnhE subunit
FOC77_RS19830	COG2212	antiporter activity
FOC77_RS19835	COG1320	monovalent cation:proton antiporter activity
FOC77_RS19855	COG0300	oxidoreductase activity
FOC77_RS19870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOC77_RS19875	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC77_RS19880	COG3584	3D domain protein
FOC77_RS19885	COG0492	ferredoxin-NADP+ reductase activity
FOC77_RS19890	COG0316	Belongs to the HesB IscA family
FOC77_RS19900	COG4844	belongs to the
FOC77_RS19905	COG1252	NADH dehydrogenase
FOC77_RS19910	COG4837	Protein of unknown function (DUF1462)
FOC77_RS19915	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC77_RS19920	COG0083	homoserine kinase activity
FOC77_RS19925	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOC77_RS19930	COG0460	homoserine dehydrogenase
FOC77_RS19935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC77_RS19940	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC77_RS19945	COG0647	UMP catabolic process
FOC77_RS19950	COG2445	Protein of unknown function DUF86
FOC77_RS19955	COG3287	FIST C domain
FOC77_RS19955	COG2200	EAL domain
FOC77_RS19955	COG2199	diguanylate cyclase activity
FOC77_RS19960	COG4470	Protein conserved in bacteria
FOC77_RS19965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC77_RS19970	COG0739	heme binding
FOC77_RS19975	COG2199	diguanylate cyclase activity
FOC77_RS19975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOC77_RS19980	COG3377	Domain of unknown function (DUF1805)
FOC77_RS19985	COG0737	Belongs to the 5'-nucleotidase family
FOC77_RS19990	COG1801	Protein of unknown function DUF72
FOC77_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS20000	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FOC77_RS20015	COG1414	Transcriptional regulator
FOC77_RS20020	COG0561	phosphatase activity
FOC77_RS20025	COG0110	maltose O-acetyltransferase activity
FOC77_RS20030	COG0346	lactoylglutathione lyase activity
FOC77_RS20040	COG1940	carbohydrate kinase activity
FOC77_RS20045	COG0719	Fe-S assembly protein
FOC77_RS20050	COG0822	iron-sulfur transferase activity
FOC77_RS20055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC77_RS20060	COG0719	Fe-S assembly protein
FOC77_RS20065	COG0396	ATPase activity
FOC77_RS20070	COG1464	Belongs to the NlpA lipoprotein family
FOC77_RS20075	COG2011	ABC-type metal ion transport system permease component
FOC77_RS20080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC77_RS20090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC77_RS20095	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC77_RS20100	COG0509	glycine decarboxylation via glycine cleavage system
FOC77_RS20105	COG1393	Belongs to the ArsC family
FOC77_RS20110	COG1960	acyl-CoA dehydrogenase activity
FOC77_RS20115	COG1024	Enoyl-CoA hydratase
FOC77_RS20115	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC77_RS20130	COG5577	PFAM Coat F domain
FOC77_RS20140	COG0772	Belongs to the SEDS family
FOC77_RS20145	COG0840	transmembrane signaling receptor activity
FOC77_RS20155	COG1126	abc transporter atp-binding protein
FOC77_RS20160	COG0765	amino acid transport
FOC77_RS20165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS20180	COG1968	undecaprenyl-diphosphatase activity
FOC77_RS20185	COG0628	permease
FOC77_RS20190	COG1033	growth of symbiont in host cell
FOC77_RS20190	COG2409	Drug exporters of the RND superfamily
FOC77_RS20195	COG1846	Transcriptional regulator
FOC77_RS20200	COG2050	protein possibly involved in aromatic compounds catabolism
FOC77_RS20210	COG0366	Alpha amylase catalytic
FOC77_RS20215	COG1609	Transcriptional regulator
FOC77_RS20220	COG1733	regulation of RNA biosynthetic process
FOC77_RS20225	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FOC77_RS20230	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOC77_RS20240	COG3764	Sortase (surface protein transpeptidase)
FOC77_RS20250	COG0488	(ABC) transporter
FOC77_RS20260	COG1609	Transcriptional regulator
FOC77_RS20265	COG0673	inositol 2-dehydrogenase activity
FOC77_RS20270	COG1874	Beta-galactosidase
FOC77_RS20275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC77_RS20280	COG0395	ABC-type sugar transport system, permease component
FOC77_RS20285	COG1175	transmembrane transport
FOC77_RS20290	COG1653	transport
FOC77_RS20295	COG2207	Transcriptional regulator
FOC77_RS20295	COG4753	response regulator
FOC77_RS20300	COG2972	Histidine kinase
FOC77_RS20310	COG5578	integral membrane protein
FOC77_RS20320	COG5577	PFAM Coat F domain
FOC77_RS20325	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS20345	COG0710	3-dehydroquinate dehydratase activity
FOC77_RS20350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC77_RS20355	COG0753	catalase activity
FOC77_RS20360	COG0656	L-ascorbic acid biosynthetic process
FOC77_RS20365	COG0395	ABC-type sugar transport system, permease component
FOC77_RS20370	COG1175	transmembrane transport
FOC77_RS20375	COG1653	transport
FOC77_RS20380	COG1486	melibiose metabolic process
FOC77_RS20385	COG2169	Transcriptional regulator
FOC77_RS20390	COG2217	Heavy metal translocating P-type atpase
FOC77_RS20395	COG2608	mercury ion transmembrane transporter activity
FOC77_RS20405	COG1802	Transcriptional regulator
FOC77_RS20415	COG2814	Major facilitator Superfamily
FOC77_RS20420	COG0789	Transcriptional regulator
FOC77_RS20425	COG2188	Transcriptional regulator
FOC77_RS20430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC77_RS20445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC77_RS20465	COG4208	sulfate ABC transporter
FOC77_RS20475	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOC77_RS20490	COG0765	amino acid transport
FOC77_RS20495	COG1126	abc transporter atp-binding protein
FOC77_RS20500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC77_RS20520	COG5337	Spore coat protein CotH
FOC77_RS20535	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS20545	COG1063	alcohol dehydrogenase
FOC77_RS20550	COG3775	system Galactitol-specific IIC component
FOC77_RS20565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS20565	COG3711	transcriptional antiterminator
FOC77_RS20575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC77_RS20580	COG0557	exoribonuclease II activity
FOC77_RS20585	COG1647	Serine aminopeptidase, S33
FOC77_RS20590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC77_RS20600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC77_RS20635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS20645	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC77_RS20650	COG1660	Displays ATPase and GTPase activities
FOC77_RS20655	COG1051	belongs to the nudix hydrolase family
FOC77_RS20665	COG0492	ferredoxin-NADP+ reductase activity
FOC77_RS20670	COG0457	Tetratricopeptide repeat
FOC77_RS20675	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC77_RS20675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC77_RS20680	COG0107	imidazoleglycerol-phosphate synthase activity
FOC77_RS20685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOC77_RS20690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC77_RS20695	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC77_RS20700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC77_RS20705	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC77_RS20710	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOC77_RS20715	COG0110	maltose O-acetyltransferase activity
FOC77_RS20720	COG0546	phosphoglycolate phosphatase activity
FOC77_RS20735	COG1950	PFAM Membrane protein of
FOC77_RS20740	COG3595	metallopeptidase activity
FOC77_RS20745	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC77_RS20750	COG0556	nucleotide-excision repair
FOC77_RS20755	COG4897	Protein conserved in bacteria
FOC77_RS20760	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS20775	COG1454	alcohol dehydrogenase
FOC77_RS20775	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS20790	COG1595	DNA-templated transcription, initiation
FOC77_RS20800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC77_RS20810	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC77_RS20815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC77_RS20820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC77_RS20825	COG2508	Transcriptional regulator
FOC77_RS20830	COG2233	PERMEase
FOC77_RS20835	COG0281	malic enzyme
FOC77_RS20840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC77_RS20870	COG1053	succinate dehydrogenase
FOC77_RS20875	COG2030	dehydratase
FOC77_RS20880	COG0789	Transcriptional regulator
FOC77_RS20885	COG1064	alcohol dehydrogenase
FOC77_RS20890	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC77_RS20895	COG4988	ABC transporter
FOC77_RS20900	COG1294	oxidase, subunit
FOC77_RS20905	COG1271	oxidase subunit
FOC77_RS20910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC77_RS20915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC77_RS20920	COG0205	6-phosphofructokinase activity
FOC77_RS20925	COG0698	ribose 5-phosphate isomerase
FOC77_RS20935	COG1063	alcohol dehydrogenase
FOC77_RS20940	COG3775	system Galactitol-specific IIC component
FOC77_RS20945	COG3414	Phosphotransferase system galactitol-specific IIB component
FOC77_RS20950	COG3414	Phosphotransferase system galactitol-specific IIB component
FOC77_RS20960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS20965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC77_RS20970	COG0205	6-phosphofructokinase activity
FOC77_RS20975	COG0698	ribose 5-phosphate isomerase
FOC77_RS20985	COG0656	L-ascorbic acid biosynthetic process
FOC77_RS20990	COG2814	Major facilitator Superfamily
FOC77_RS20995	COG1733	regulation of RNA biosynthetic process
FOC77_RS21005	COG0793	Belongs to the peptidase S41A family
FOC77_RS21005	COG3409	Peptidoglycan-binding domain 1 protein
FOC77_RS21010	COG3546	catalase activity
FOC77_RS21015	COG2217	Heavy metal translocating P-type atpase
FOC77_RS21020	COG0640	Transcriptional regulator
FOC77_RS21035	COG0739	heme binding
FOC77_RS21040	COG2177	Part of the ABC transporter FtsEX involved in
FOC77_RS21045	COG2884	Cell division ATP-binding protein ftsE
FOC77_RS21050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC77_RS21070	COG0463	Glycosyl transferase, family 2
FOC77_RS21080	COG0653	protein targeting
FOC77_RS21100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOC77_RS21105	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC77_RS21110	COG3842	ATPase activity
FOC77_RS21125	COG1802	Transcriptional regulator
FOC77_RS21135	COG2059	Chromate
FOC77_RS21140	COG2059	Chromate
FOC77_RS21160	COG1522	sequence-specific DNA binding
FOC77_RS21170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC77_RS21180	COG1516	flagellar protein fliS
FOC77_RS21185	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC77_RS21195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC77_RS21200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC77_RS21205	COG2089	acid synthase
FOC77_RS21215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC77_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS21235	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FOC77_RS21250	COG1442	glycosyl transferase family 8
FOC77_RS21270	COG1086	Polysaccharide biosynthesis protein
FOC77_RS21280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC77_RS21285	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOC77_RS21290	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FOC77_RS21295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC77_RS21300	COG4786	Flagellar basal body rod
FOC77_RS21300	COG1256	bacterial-type flagellum assembly
FOC77_RS21315	COG1728	Protein conserved in bacteria
FOC77_RS21325	COG1516	flagellar protein fliS
FOC77_RS21345	COG1040	competence protein
FOC77_RS21350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC77_RS21365	COG1307	EDD domain protein, DegV family
FOC77_RS21370	COG2197	response regulator
FOC77_RS21375	COG4585	Histidine kinase
FOC77_RS21380	COG1739	Uncharacterized protein family UPF0029
FOC77_RS21385	COG1316	TRANSCRIPTIONal
FOC77_RS21395	COG2385	sporulation resulting in formation of a cellular spore
FOC77_RS21395	COG2247	cell wall binding repeat
FOC77_RS21400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC77_RS21405	COG1134	teichoic acid transport
FOC77_RS21410	COG1682	transport, permease protein
FOC77_RS21415	COG1316	TRANSCRIPTIONal
FOC77_RS21420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC77_RS21425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC77_RS21430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOC77_RS21450	COG0346	lactoylglutathione lyase activity
FOC77_RS21455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC77_RS21460	COG0366	Alpha amylase catalytic
FOC77_RS21465	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOC77_RS21480	COG0629	single-stranded DNA binding
FOC77_RS21485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC77_RS21490	COG4297	protein containing double-stranded beta helix domain
FOC77_RS21495	COG0840	transmembrane signaling receptor activity
FOC77_RS21495	COG5278	phosphoserine phosphatase activity
FOC77_RS21500	COG2814	Major facilitator Superfamily
FOC77_RS21505	COG1335	isochorismatase
FOC77_RS21510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC77_RS21515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC77_RS21530	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS21550	COG0604	alcohol dehydrogenase
FOC77_RS21560	COG1660	Displays ATPase and GTPase activities
FOC77_RS21565	COG0371	Dehydrogenase
FOC77_RS21570	COG2084	Dehydrogenase
FOC77_RS21575	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC77_RS21580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC77_RS21585	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOC77_RS21605	COG3339	Conserved Protein
FOC77_RS21610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC77_RS21625	COG2011	ABC-type metal ion transport system permease component
FOC77_RS21630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC77_RS21650	COG0745	RESPONSE REGULATOR receiver
FOC77_RS21655	COG0642	Histidine kinase
FOC77_RS21660	COG1136	(ABC) transporter
FOC77_RS21665	COG0577	efflux transmembrane transporter activity
FOC77_RS21685	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC77_RS21690	COG4191	Histidine kinase
FOC77_RS21710	COG0300	oxidoreductase activity
FOC77_RS21715	COG0656	L-ascorbic acid biosynthetic process
FOC77_RS21725	COG0778	Nitroreductase
FOC77_RS21740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC77_RS21750	COG0561	phosphatase activity
FOC77_RS21775	COG1164	Oligoendopeptidase f
FOC77_RS21780	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS21785	COG2188	Transcriptional regulator
FOC77_RS21795	COG0840	transmembrane signaling receptor activity
FOC77_RS21795	COG5278	phosphoserine phosphatase activity
FOC77_RS21810	COG1695	Transcriptional regulator
FOC77_RS21820	COG0191	fructose-bisphosphate aldolase activity
FOC77_RS21825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS21825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS21825	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOC77_RS21830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC77_RS21865	COG2124	cytochrome p450
FOC77_RS21870	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS21875	COG2814	Major facilitator Superfamily
FOC77_RS21880	COG0383	alpha-mannosidase activity
FOC77_RS21900	COG4753	response regulator
FOC77_RS21900	COG2207	Transcriptional regulator
FOC77_RS21905	COG2972	Histidine kinase
FOC77_RS21920	COG0395	ABC-type sugar transport system, permease component
FOC77_RS21925	COG1175	transmembrane transport
FOC77_RS21930	COG2207	Transcriptional regulator
FOC77_RS21935	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS21940	COG0477	Major facilitator Superfamily
FOC77_RS21945	COG1309	transcriptional regulator
FOC77_RS21955	COG0778	Nitroreductase
FOC77_RS21960	COG2207	Transcriptional regulator
FOC77_RS21960	COG4753	response regulator
FOC77_RS21965	COG2972	Histidine kinase
FOC77_RS21980	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC77_RS21985	COG0395	ABC-type sugar transport system, permease component
FOC77_RS21990	COG4209	transmembrane transport
FOC77_RS22000	COG2188	Transcriptional regulator
FOC77_RS22005	COG4948	Mandelate Racemase Muconate Lactonizing
FOC77_RS22010	COG2190	(PTS) system
FOC77_RS22010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS22010	COG1263	PTS System
FOC77_RS22020	COG1178	ABC-type Fe3 transport system permease component
FOC77_RS22025	COG3842	ATPase activity
FOC77_RS22030	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC77_RS22035	COG4753	response regulator
FOC77_RS22035	COG2207	Transcriptional regulator
FOC77_RS22045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS22045	COG1263	PTS System
FOC77_RS22060	COG3835	regulator
FOC77_RS22065	COG1929	Belongs to the glycerate kinase type-1 family
FOC77_RS22070	COG2610	gluconate transmembrane transporter activity
FOC77_RS22090	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC77_RS22095	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC77_RS22100	COG3842	ATPase activity
FOC77_RS22105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC77_RS22120	COG1988	membrane-bound metal-dependent
FOC77_RS22125	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS22130	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS22135	COG2190	(PTS) system
FOC77_RS22135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS22135	COG1263	PTS System
FOC77_RS22145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC77_RS22150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS22155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC77_RS22160	COG2197	response regulator
FOC77_RS22165	COG2200	EAL domain
FOC77_RS22165	COG2199	diguanylate cyclase activity
FOC77_RS22170	COG3279	Response regulator of the LytR AlgR family
FOC77_RS22175	COG1309	transcriptional regulator
FOC77_RS22180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC77_RS22225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS22230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC77_RS22240	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC77_RS22265	COG1316	TRANSCRIPTIONal
FOC77_RS22275	COG2340	Cysteine-rich secretory protein family
FOC77_RS22280	COG4193	domain, Protein
FOC77_RS22300	COG2153	protein acetylation
FOC77_RS22310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS22315	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC77_RS22325	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS22330	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS22335	COG2188	Transcriptional regulator
FOC77_RS22340	COG2368	4-hydroxyphenylacetate
FOC77_RS22360	COG0673	inositol 2-dehydrogenase activity
FOC77_RS22370	COG0395	ABC-type sugar transport system, permease component
FOC77_RS22375	COG1175	transmembrane transport
FOC77_RS22385	COG1940	carbohydrate kinase activity
FOC77_RS22405	COG2720	vancomycin resistance protein
FOC77_RS22410	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC77_RS22415	COG1129	ABC transporter
FOC77_RS22420	COG1879	ABC-type sugar transport system periplasmic component
FOC77_RS22425	COG0673	inositol 2-dehydrogenase activity
FOC77_RS22430	COG1609	Transcriptional regulator
FOC77_RS22435	COG0346	lactoylglutathione lyase activity
FOC77_RS22440	COG2124	cytochrome p450
FOC77_RS22460	COG4977	sequence-specific DNA binding
FOC77_RS22480	COG1136	(ABC) transporter
FOC77_RS22485	COG0577	efflux transmembrane transporter activity
FOC77_RS22495	COG1609	Transcriptional regulator
FOC77_RS22510	COG2160	L-arabinose isomerase activity
FOC77_RS22530	COG2843	Capsule synthesis protein
FOC77_RS22555	COG3279	Response regulator of the LytR AlgR family
FOC77_RS22560	COG0745	RESPONSE REGULATOR receiver
FOC77_RS22560	COG2972	Histidine kinase
FOC77_RS22565	COG2079	MmgE PrpD family protein
FOC77_RS22570	COG1473	amidohydrolase
FOC77_RS22575	COG1126	abc transporter atp-binding protein
FOC77_RS22580	COG0765	amino acid transport
FOC77_RS22585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS22590	COG0456	acetyltransferase
FOC77_RS22600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC77_RS22605	COG0436	Aminotransferase
FOC77_RS22610	COG0371	Dehydrogenase
FOC77_RS22625	COG4895	conserved protein (DUF2196)
FOC77_RS22640	COG1846	Transcriptional regulator
FOC77_RS22650	COG2814	Major facilitator Superfamily
FOC77_RS22655	COG0395	ABC-type sugar transport system, permease component
FOC77_RS22660	COG1175	transmembrane transport
FOC77_RS22670	COG0165	Argininosuccinate lyase
FOC77_RS22680	COG1940	carbohydrate kinase activity
FOC77_RS22695	COG0840	transmembrane signaling receptor activity
FOC77_RS22700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS22710	COG0673	inositol 2-dehydrogenase activity
FOC77_RS22720	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC77_RS22725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS22730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS22730	COG3711	transcriptional antiterminator
FOC77_RS22740	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS22755	COG5002	protein histidine kinase activity
FOC77_RS22760	COG0745	RESPONSE REGULATOR receiver
FOC77_RS22765	COG0800	Aldolase
FOC77_RS22770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC77_RS22775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC77_RS22780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC77_RS22785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS22785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS22805	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC77_RS22855	COG1131	(ABC) transporter
FOC77_RS22860	COG2205	protein histidine kinase activity
FOC77_RS22865	COG0745	RESPONSE REGULATOR receiver
FOC77_RS22870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC77_RS22880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC77_RS22890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC77_RS22895	COG3716	PTS system mannose fructose sorbose family IID component
FOC77_RS22900	COG3715	PTS system
FOC77_RS22910	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS22910	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS22915	COG1940	carbohydrate kinase activity
FOC77_RS22915	COG1846	Transcriptional regulator
FOC77_RS22920	COG4821	SIS domain
FOC77_RS22930	COG1402	creatininase
FOC77_RS22955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS22965	COG1141	Ferredoxin
FOC77_RS22970	COG0402	S-adenosylhomocysteine deaminase activity
FOC77_RS22975	COG0402	S-adenosylhomocysteine deaminase activity
FOC77_RS22985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC77_RS23005	COG2271	Major facilitator Superfamily
FOC77_RS23010	COG4948	Mandelate Racemase Muconate Lactonizing
FOC77_RS23015	COG0800	Aldolase
FOC77_RS23020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS23025	COG1414	Transcriptional regulator
FOC77_RS23040	COG1522	sequence-specific DNA binding
FOC77_RS23045	COG2190	(PTS) system
FOC77_RS23045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS23045	COG1263	PTS System
FOC77_RS23050	COG3711	transcriptional antiterminator
FOC77_RS23075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS23075	COG2190	(PTS) system
FOC77_RS23075	COG1263	PTS System
FOC77_RS23095	COG1940	carbohydrate kinase activity
FOC77_RS23100	COG1940	carbohydrate kinase activity
FOC77_RS23105	COG2188	Transcriptional regulator
FOC77_RS23110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC77_RS23115	COG4821	SIS domain
FOC77_RS23125	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC77_RS23135	COG3420	alginic acid biosynthetic process
FOC77_RS23165	COG0543	2 iron, 2 sulfur cluster binding
FOC77_RS23170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC77_RS23180	COG2814	Major facilitator Superfamily
FOC77_RS23190	COG0679	Auxin Efflux Carrier
FOC77_RS23195	COG0281	malic enzyme
FOC77_RS23215	COG0402	S-adenosylhomocysteine deaminase activity
FOC77_RS23225	COG2190	(PTS) system
FOC77_RS23225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS23225	COG1263	PTS System
FOC77_RS23230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS23235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC77_RS23240	COG1609	Transcriptional regulator
FOC77_RS23270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC77_RS23285	COG0662	Cupin 2, conserved barrel domain protein
FOC77_RS23285	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOC77_RS23320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC77_RS23325	COG4464	protein tyrosine phosphatase activity
FOC77_RS23330	COG0489	protein tyrosine kinase activity
FOC77_RS23335	COG3944	biosynthesis protein
FOC77_RS23345	COG1396	sequence-specific DNA binding
FOC77_RS23370	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOC77_RS23370	COG0662	Cupin 2, conserved barrel domain protein
FOC77_RS23375	COG1132	(ABC) transporter
FOC77_RS23395	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS23405	COG5039	Polysaccharide pyruvyl transferase
FOC77_RS23440	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS23450	COG0438	transferase activity, transferring glycosyl groups
FOC77_RS23460	COG1215	transferase activity, transferring glycosyl groups
FOC77_RS23465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC77_RS23470	COG0489	protein tyrosine kinase activity
FOC77_RS23475	COG3944	biosynthesis protein
FOC77_RS23480	COG2247	cell wall binding repeat
FOC77_RS23480	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC77_RS23485	COG0668	transmembrane transport
FOC77_RS23510	COG2814	Major facilitator Superfamily
FOC77_RS23515	COG0789	Transcriptional regulator
FOC77_RS23515	COG4978	Transcriptional regulator
FOC77_RS23525	COG1846	Transcriptional regulator
FOC77_RS23530	COG1132	(ABC) transporter
FOC77_RS23560	COG2002	toxin-antitoxin pair type II binding
FOC77_RS23565	COG2199	diguanylate cyclase activity
FOC77_RS23570	COG1742	UPF0060 membrane protein
FOC77_RS23585	COG2199	diguanylate cyclase activity
FOC77_RS23585	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FOC77_RS23590	COG1846	Transcriptional regulator
FOC77_RS23595	COG1566	PFAM secretion protein HlyD family protein
FOC77_RS23600	COG2814	Major facilitator Superfamily
FOC77_RS23605	COG3328	transposase activity
FOC77_RS23610	COG0673	inositol 2-dehydrogenase activity
FOC77_RS23620	COG2814	Major facilitator Superfamily
FOC77_RS23625	COG0596	Alpha beta hydrolase
FOC77_RS23630	COG1309	transcriptional regulator
FOC77_RS23655	COG0395	ABC-type sugar transport system, permease component
FOC77_RS23660	COG1175	transmembrane transport
FOC77_RS23675	COG0534	Mate efflux family protein
FOC77_RS23680	COG2942	2-epimerase
FOC77_RS23690	COG0667	Aldo Keto reductase
FOC77_RS23695	COG1940	carbohydrate kinase activity
FOC77_RS23700	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS23710	COG3458	cephalosporin-C deacetylase activity
FOC77_RS23715	COG1609	Transcriptional regulator
FOC77_RS23720	COG0701	Predicted permease
FOC77_RS23725	COG0709	Synthesizes selenophosphate from selenide and ATP
FOC77_RS23730	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FOC77_RS23740	COG3328	transposase activity
FOC77_RS23745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC77_RS23750	COG1388	LysM domain
FOC77_RS23755	COG4191	Histidine kinase
FOC77_RS23800	COG1408	metallophosphoesterase
FOC77_RS23810	COG2197	response regulator
FOC77_RS23815	COG4585	Histidine kinase
FOC77_RS23820	COG0842	Transport permease protein
FOC77_RS23825	COG1131	(ABC) transporter
FOC77_RS23850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC77_RS23855	COG1028	Short-chain dehydrogenase reductase Sdr
FOC77_RS23865	COG0697	spore germination
FOC77_RS23870	COG0791	NLP P60 protein
FOC77_RS23870	COG1388	LysM domain
FOC77_RS23905	COG2719	SpoVR family
FOC77_RS23910	COG0768	penicillin binding
FOC77_RS23915	COG3011	Protein conserved in bacteria
FOC77_RS23925	COG1388	LysM domain
FOC77_RS23925	COG0791	NLP P60 protein
FOC77_RS23935	COG4715	Zinc finger, swim domain protein
FOC77_RS23940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC77_RS23970	COG4786	Flagellar basal body rod
FOC77_RS23975	COG4786	Flagellar basal body rod
FOC77_RS23980	COG1077	Cell shape determining protein MreB Mrl
FOC77_RS23985	COG1609	Transcriptional regulator
FOC77_RS23990	COG0739	heme binding
FOC77_RS23995	COG2385	sporulation resulting in formation of a cellular spore
FOC77_RS24000	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC77_RS24010	COG4836	Membrane
FOC77_RS24015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC77_RS24020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOC77_RS24025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOC77_RS24035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC77_RS24040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC77_RS24045	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC77_RS24050	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC77_RS24060	COG1404	Belongs to the peptidase S8 family
FOC77_RS24065	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOC77_RS24070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOC77_RS24080	COG0840	transmembrane signaling receptor activity
FOC77_RS24090	COG1971	Probably functions as a manganese efflux pump
FOC77_RS24095	COG0009	L-threonylcarbamoyladenylate synthase
FOC77_RS24115	COG1012	belongs to the aldehyde dehydrogenase family
FOC77_RS24120	COG0506	proline dehydrogenase activity
FOC77_RS24125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC77_RS24130	COG1321	iron dependent repressor
FOC77_RS24130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC77_RS24135	COG1121	(ABC) transporter
FOC77_RS24140	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC77_RS24155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC77_RS24160	COG1366	Belongs to the anti-sigma-factor antagonist family
FOC77_RS24165	COG1253	flavin adenine dinucleotide binding
FOC77_RS24170	COG1253	flavin adenine dinucleotide binding
FOC77_RS24180	COG1435	thymidine kinase activity
FOC77_RS24190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC77_RS24200	COG0191	fructose-bisphosphate aldolase activity
FOC77_RS24205	COG2204	response regulator
FOC77_RS24210	COG4821	SIS domain
FOC77_RS24215	COG0504	CTP synthase activity
FOC77_RS24220	COG3343	RNA polymerase activity
FOC77_RS24225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC77_RS24235	COG3279	Response regulator of the LytR AlgR family
FOC77_RS24240	COG4555	ABC transporter
FOC77_RS24245	COG1668	transmembrane transport
FOC77_RS24260	COG1131	(ABC) transporter
FOC77_RS24285	COG0018	arginyl-trna synthetase
FOC77_RS24290	COG4506	Protein conserved in bacteria
FOC77_RS24300	COG0010	Belongs to the arginase family
FOC77_RS24305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC77_RS24310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC77_RS24315	COG1193	negative regulation of DNA recombination
FOC77_RS24325	COG1994	Peptidase M50
FOC77_RS24330	COG1942	4-Oxalocrotonate Tautomerase
FOC77_RS24335	COG3465	dGTPase activity
FOC77_RS24340	COG1078	dGTPase activity
FOC77_RS24345	COG4844	belongs to the
FOC77_RS24350	COG0477	Major facilitator Superfamily
FOC77_RS24365	COG0280	phosphate acetyltransferase
FOC77_RS24380	COG2363	Small membrane protein
FOC77_RS24395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC77_RS24410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC77_RS24415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOC77_RS24420	COG0314	molybdopterin synthase activity
FOC77_RS24425	COG0351	phosphomethylpyrimidine kinase
FOC77_RS24430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC77_RS24450	COG1131	(ABC) transporter
FOC77_RS24465	COG0561	phosphatase activity
FOC77_RS24470	COG1271	oxidase subunit
FOC77_RS24475	COG1294	oxidase, subunit
FOC77_RS24480	COG4988	ABC transporter
FOC77_RS24485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC77_RS24490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC77_RS24495	COG2226	methyltransferase
FOC77_RS24500	COG0492	ferredoxin-NADP+ reductase activity
FOC77_RS24505	COG1486	melibiose metabolic process
FOC77_RS24515	COG2966	Psort location CytoplasmicMembrane, score
FOC77_RS24535	COG1131	(ABC) transporter
FOC77_RS24540	COG0686	Belongs to the AlaDH PNT family
FOC77_RS24545	COG2508	Transcriptional regulator
FOC77_RS24545	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FOC77_RS24555	COG1486	melibiose metabolic process
FOC77_RS24560	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC77_RS24565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS24570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS24575	COG2188	Transcriptional regulator
FOC77_RS24585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC77_RS24590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC77_RS24600	COG0385	Bile acid
FOC77_RS24605	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC77_RS24610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS24615	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS24620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS24625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC77_RS24625	COG3711	transcriptional antiterminator
FOC77_RS24635	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC77_RS24685	COG2508	Transcriptional regulator
FOC77_RS24695	COG0477	Major facilitator Superfamily
FOC77_RS24700	COG0534	Mate efflux family protein
FOC77_RS24710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC77_RS24720	COG1609	Transcriptional regulator
FOC77_RS24730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOC77_RS24735	COG1609	Transcriptional regulator
FOC77_RS24745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC77_RS24750	COG1554	hydrolase, family 65, central catalytic
FOC77_RS24760	COG3833	ABC-type maltose transport systems, permease component
FOC77_RS24765	COG1175	transmembrane transport
FOC77_RS24770	COG2182	Extracellular solute-binding protein
FOC77_RS24775	COG1263	PTS System
FOC77_RS24775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC77_RS24780	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC77_RS24785	COG1122	ATPase activity
FOC77_RS24790	COG4721	ABC-type cobalt transport system, permease component
FOC77_RS24795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC77_RS24805	COG3695	enzyme binding
FOC77_RS24815	COG0411	ABC transporter
FOC77_RS24825	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOC77_RS24840	COG0492	ferredoxin-NADP+ reductase activity
FOC77_RS24850	COG4176	ABC-type proline glycine betaine transport system permease component
FOC77_RS24860	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC77_RS24875	COG1073	alpha beta
FOC77_RS24885	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC77_RS24890	COG1653	transport
FOC77_RS24900	COG4209	transmembrane transport
FOC77_RS24905	COG0395	ABC-type sugar transport system, permease component
FOC77_RS24910	COG2207	Transcriptional regulator
FOC77_RS24915	COG1609	Transcriptional regulator
FOC77_RS24920	COG2721	sulfolactate sulfo-lyase activity
FOC77_RS24925	COG1904	glucuronate isomerase
FOC77_RS24930	COG2755	lipolytic protein G-D-S-L family
FOC77_RS24930	COG0657	acetylesterase activity
FOC77_RS24935	COG2755	lipolytic protein G-D-S-L family
FOC77_RS24945	COG1132	(ABC) transporter
FOC77_RS24950	COG2814	Major facilitator Superfamily
FOC77_RS24980	COG2072	flavoprotein involved in K transport
FOC77_RS25015	COG2208	phosphoserine phosphatase activity
FOC77_RS25020	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC77_RS25025	COG0784	Response regulator, receiver
FOC77_RS25025	COG2198	Histidine kinase
FOC77_RS25025	COG2205	protein histidine kinase activity
FOC77_RS25035	COG4608	Belongs to the ABC transporter superfamily
FOC77_RS25040	COG0444	Belongs to the ABC transporter superfamily
FOC77_RS25045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC77_RS25050	COG0601	transmembrane transport
FOC77_RS25055	COG4166	transmembrane transport
FOC77_RS25065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC77_RS25075	COG4989	oxidoreductase activity
FOC77_RS25080	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC77_RS25085	COG1320	monovalent cation:proton antiporter activity
FOC77_RS25090	COG2212	antiporter activity
FOC77_RS25095	COG1863	multisubunit Na H antiporter MnhE subunit
FOC77_RS25100	COG0651	ATP synthesis coupled electron transport
FOC77_RS25110	COG2111	Na H antiporter
FOC77_RS25125	COG0582	viral genome integration into host DNA
FOC77_RS25130	COG0124	histidyl-tRNA synthetase
FOC77_RS25135	COG3142	Participates in the control of copper homeostasis
FOC77_RS25145	COG1609	Transcriptional regulator
FOC77_RS25150	COG3459	Glycosyltransferase 36 associated
FOC77_RS25160	COG0395	ABC-type sugar transport system, permease component
FOC77_RS25165	COG1175	transmembrane transport
FOC77_RS25170	COG2182	Extracellular solute-binding protein
FOC77_RS25175	COG5039	Polysaccharide pyruvyl transferase
FOC77_RS25180	COG1994	Peptidase M50
FOC77_RS25185	COG2336	PFAM SpoVT AbrB
FOC77_RS25205	COG4555	ABC transporter
FOC77_RS25215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC77_RS25220	COG0450	alkyl hydroperoxide reductase
FOC77_RS25225	COG3634	alkyl hydroperoxide reductase activity
FOC77_RS25240	COG4166	transmembrane transport
FOC77_RS25250	COG2723	6-phospho-beta-galactosidase activity
FOC77_RS25260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS25265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC77_RS25270	COG3507	Belongs to the glycosyl hydrolase 43 family