locus-tag	class	description
HLK66_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HLK66_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLK66_RS00015	ENOG410848D	S4 domain protein YaaA
HLK66_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HLK66_RS00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLK66_RS00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HLK66_RS00040	ENOG4105DHT	Metal Dependent Phosphohydrolase
HLK66_RS00075	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HLK66_RS00085	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
HLK66_RS00090	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HLK66_RS00105	ENOG4105ZMH	deoxynucleoside kinase
HLK66_RS00115	ENOG4108VEU	Thiamine monophosphate synthase
HLK66_RS00130	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HLK66_RS00135	ENOG4105D06	uba thif-type nad fad binding protein
HLK66_RS00140	ENOG4105VRS	hydrolase family 18
HLK66_RS00145	ENOG4105GTG	Isochorismatase
HLK66_RS00150	ENOG4108Z6B	deaminase
HLK66_RS00160	ENOG4105C6E	dna polymerase iii
HLK66_RS00165	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HLK66_RS00170	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HLK66_RS00180	ENOG41067KS	pro-sigma K processing
HLK66_RS00215	ENOG4105CXN	decarboxylase
HLK66_RS00225	ENOG4105X0R	protein from nitrogen regulatory protein P-II
HLK66_RS00230	ENOG4105XVJ	Protein of unknown function (DUF327)
HLK66_RS00235	ENOG4105FA2	dna polymerase iii
HLK66_RS00240	ENOG4105MA4	psp1 domain protein
HLK66_RS00245	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
HLK66_RS00250	ENOG41060K3	Methyltransferase
HLK66_RS00255	ENOG4105VC4	domain protein
HLK66_RS00260	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HLK66_RS00265	ENOG4105KRN	Transcriptional regulator, abrb family
HLK66_RS00270	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HLK66_RS00275	ENOG4105F8V	Hydrolase, tatD family
HLK66_RS00280	ENOG41069ER	domain protein
HLK66_RS00285	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
HLK66_RS00290	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HLK66_RS00295	ENOG4105XFA	sporulation peptidase YabG
HLK66_RS00300	ENOG4105W42	Veg protein
HLK66_RS00310	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HLK66_RS00315	ENOG4105DFT	pur operon repressor
HLK66_RS00320	ENOG4105KME	endoribonuclease L-psp
HLK66_RS00325	ENOG4105K4W	Could be involved in septation (By similarity)
HLK66_RS00330	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HLK66_RS00335	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HLK66_RS00340	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HLK66_RS00355	ENOG4108JA2	transcriptioN-repair coupling factor
HLK66_RS00360	ENOG4108M14	stage v sporulation protein t
HLK66_RS00380	ENOG4108IY2	MazG family
HLK66_RS00385	ENOG41082I2	s4 domain protein
HLK66_RS00390	ENOG4105VYY	sporulation protein yabp
HLK66_RS00405	ENOG41060GV	RNA binding s1 domain protein
HLK66_RS00430	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HLK66_RS00435	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HLK66_RS00445	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HLK66_RS00450	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HLK66_RS00455	ENOG4105C6T	cysteine synthase
HLK66_RS00460	ENOG4105CRQ	synthase (Component I)
HLK66_RS00465	ENOG4105DDQ	anthranilate synthase
HLK66_RS00470	ENOG41082R7	4-amino-4-deoxychorismate lyase EC 4.1.3.38
HLK66_RS00475	ENOG4105EEI	dihydropteroate synthase
HLK66_RS00480	ENOG4105KRF	dihydroneopterin aldolase
HLK66_RS00485	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLK66_RS00495	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HLK66_RS00500	ENOG4105CRK	lysyL-tRNA synthetase
HLK66_RS00585	ENOG4108Z0C	Uvrb UvrC protein
HLK66_RS00590	ENOG41066A3	ATP guanido phosphotransferase
HLK66_RS00600	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HLK66_RS00605	ENOG4105CTP	PilT protein domain protein
HLK66_RS00610	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HLK66_RS00615	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HLK66_RS00620	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HLK66_RS00625	ENOG4105D7W	serine acetyltransferase
HLK66_RS00630	ENOG4105C8N	cysteinyl-tRNA synthetase
HLK66_RS00640	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HLK66_RS00645	ENOG4105M0M	Tetracycline resistance protein
HLK66_RS00650	ENOG4105QIV	RNA polymerase
HLK66_RS00655	ENOG4107FTN	50S ribosomal protein L33
HLK66_RS00665	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HLK66_RS00675	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HLK66_RS00685	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HLK66_RS00690	ENOG4107Y49	methyltransferase
HLK66_RS00695	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLK66_RS00700	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLK66_RS00705	ENOG4105XPM	ribosomal protein
HLK66_RS00710	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HLK66_RS00715	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HLK66_RS00725	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HLK66_RS00740	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HLK66_RS00745	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HLK66_RS00750	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLK66_RS00755	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HLK66_RS00765	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HLK66_RS00770	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HLK66_RS00775	ENOG41082SA	50s ribosomal protein l29
HLK66_RS00780	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HLK66_RS00785	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HLK66_RS00805	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HLK66_RS00810	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HLK66_RS00815	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HLK66_RS00820	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HLK66_RS00825	ENOG4105VPB	50S ribosomal protein L30
HLK66_RS00830	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HLK66_RS00835	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HLK66_RS00840	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HLK66_RS00845	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HLK66_RS00855	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLK66_RS00865	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HLK66_RS00870	ENOG4108ZT0	50S ribosomal protein l17
HLK66_RS00875	ENOG4108JJB	ABC transporter
HLK66_RS00880	ENOG4108JJB	ABC transporter
HLK66_RS00885	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
HLK66_RS00895	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HLK66_RS00955	ENOG4105CS2	ec 3.2.1.21
HLK66_RS00960	ENOG4105C5Y	PTS System
HLK66_RS00970	ENOG4105C5Y	PTS System
HLK66_RS00985	ENOG41079CX	
HLK66_RS01015	ENOG4105D1F	ATP-binding protein
HLK66_RS01025	ENOG4108NMV	polysaccharide deacetylase
HLK66_RS01100	ENOG4105EMN	RNA polymerase sigma factor
HLK66_RS01110	ENOG4105C8B	TIGR00159 family
HLK66_RS01115	ENOG4107U5W	ybbr family
HLK66_RS01120	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HLK66_RS01125	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLK66_RS01150	ENOG4105FS7	Transcriptional regulator
HLK66_RS01165	ENOG4108TVJ	Nitroreductase
HLK66_RS01180	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK66_RS01210	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS01235	ENOG4105KVH	Transcriptional regulator
HLK66_RS01245	ENOG4105C26	Dehydrogenase
HLK66_RS01255	ENOG4105CPQ	Dehydrogenase
HLK66_RS01260	ENOG410787A	Pts system, glucitol sorbitol-specific
HLK66_RS01265	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HLK66_RS01270	ENOG4105VI0	Pts system, glucitol sorbitol-specific
HLK66_RS01295	ENOG4105DAS	pts system
HLK66_RS01300	ENOG4105DAS	pts system
HLK66_RS01310	ENOG4105F3R	pts system mannose fructose sorbose family iid
HLK66_RS01315	ENOG4105DJ2	Major Facilitator Superfamily
HLK66_RS01320	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS01325	ENOG4105CHR	reductase
HLK66_RS01340	ENOG4105DJ2	Major Facilitator Superfamily
HLK66_RS01355	ENOG4105DQ5	transport system permease protein
HLK66_RS01360	ENOG4105TVJ	transport system, permease
HLK66_RS01365	ENOG4105E0A	ABC, transporter
HLK66_RS01370	ENOG4105CZN	Potassium uptake protein
HLK66_RS01390	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
HLK66_RS01395	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
HLK66_RS01410	ENOG4105D29	Helix-turn-helix type 11 domain protein
HLK66_RS01420	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HLK66_RS01425	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HLK66_RS01440	ENOG4105C3M	thioredoxin reductase
HLK66_RS01445	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HLK66_RS01455	ENOG4108YM7	Gcn5-related n-acetyltransferase
HLK66_RS01480	ENOG4105EMN	RNA polymerase sigma factor
HLK66_RS01490	ENOG4108KGH	TRANSCRIPTIONal
HLK66_RS01500	ENOG4105I4A	GCN5-related N-acetyltransferase
HLK66_RS01540	ENOG4107FKK	extracellular solute-binding protein family 1
HLK66_RS01550	ENOG4105EG2	ABC transporter, permease
HLK66_RS01570	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HLK66_RS01575	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HLK66_RS01580	ENOG4105DUM	transcriptional regulator, lysR family
HLK66_RS01595	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HLK66_RS01605	ENOG4107RIQ	Sulfate adenylate transferase
HLK66_RS01610	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HLK66_RS01615	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HLK66_RS01620	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
HLK66_RS01625	ENOG4108Z73	Siroheme synthase
HLK66_RS01640	ENOG4105BZU	Histidine kinase
HLK66_RS01665	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HLK66_RS01675	ENOG4105EWU	Squalene--hopene cyclase
HLK66_RS01680	ENOG4105C5S	asparaginyl-tRNA synthetase
HLK66_RS01685	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
HLK66_RS01690	ENOG4105CHH	sulfate transporter
HLK66_RS01700	ENOG41067QW	Transcriptional regulator
HLK66_RS01705	ENOG4105F8D	glycoside hydrolase family 4
HLK66_RS01710	ENOG4105CI1	PTS System
HLK66_RS01715	ENOG4105HX0	Transcriptional regulator
HLK66_RS01735	ENOG4105CK1	PTS System
HLK66_RS01745	ENOG4105C72	UPF0176 protein
HLK66_RS01760	ENOG4105E0C	molybdate abc transporter
HLK66_RS01765	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HLK66_RS01770	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLK66_RS01805	ENOG4105CEP	NADH dehydrogenase
HLK66_RS01820	ENOG4108JJB	ABC transporter
HLK66_RS01835	ENOG4105D3Q	Sugar transferase
HLK66_RS01840	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HLK66_RS01845	ENOG4107RA4	Glycosyl transferase (Group 1
HLK66_RS01850	ENOG4105CMR	udp-glucose 4-epimerase
HLK66_RS01855	ENOG4105QZI	O-Antigen Polymerase
HLK66_RS01870	ENOG4107EF8	Glycosyl transferase (Group 1
HLK66_RS01875	ENOG4108Z40	Transcriptional regulator
HLK66_RS01880	ENOG4105C1Q	protoporphyrinogen oxidase
HLK66_RS01895	ENOG4108ME1	Peptidase M55 D-aminopeptidase
HLK66_RS01900	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS01905	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS01910	ENOG4105C3U	ABC transporter
HLK66_RS01920	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HLK66_RS01925	ENOG4105DTQ	mandelate racemase muconate lactonizing
HLK66_RS01930	ENOG4107SN7	NLP P60 protein
HLK66_RS01935	ENOG4108JQ7	(ABC) transporter
HLK66_RS01945	ENOG4105E0A	ABC, transporter
HLK66_RS01960	ENOG4107SET	aldo keto reductase
HLK66_RS01965	ENOG4105C01	Dihydroxy-acid dehydratase
HLK66_RS01970	ENOG4106F5Q	Membrane
HLK66_RS01980	ENOG4105C37	(CBS) domain
HLK66_RS01990	ENOG4105ETD	TRANSCRIPTIONal
HLK66_RS02000	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HLK66_RS02005	ENOG4105BZ4	penicillin-binding protein
HLK66_RS02010	ENOG4105E2S	oxidase) subunit II
HLK66_RS02015	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HLK66_RS02030	ENOG4105DHS	permease protein
HLK66_RS02035	ENOG4105CM4	permease protein
HLK66_RS02040	ENOG4108IPW	abc transporter atp-binding protein
HLK66_RS02050	ENOG4105EE0	oxidoreductase
HLK66_RS02055	ENOG4105EVU	fructokinase
HLK66_RS02060	ENOG4105BZU	Histidine kinase
HLK66_RS02065	ENOG4105C0H	protease
HLK66_RS02070	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HLK66_RS02100	ENOG4105F38	ABC transporter, permease
HLK66_RS02105	ENOG4105D38	putrescine abc transporter
HLK66_RS02110	ENOG4107RUE	extracellular solute-binding protein family 1
HLK66_RS02115	ENOG4105PXI	polysaccharide deacetylase
HLK66_RS02125	ENOG4107ZYR	domain protein
HLK66_RS02130	ENOG4105HUF	DNA protection during starvation protein
HLK66_RS02140	ENOG4105CJW	magnesium transporter
HLK66_RS02145	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HLK66_RS02155	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HLK66_RS02160	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HLK66_RS02170	ENOG4105E0A	ABC, transporter
HLK66_RS02175	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HLK66_RS02180	ENOG4107QZB	decarboxylase
HLK66_RS02190	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HLK66_RS02195	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HLK66_RS02200	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HLK66_RS02205	ENOG4108WBT	adenosyltransferase
HLK66_RS02220	ENOG4105CPF	Cell wall formation (By similarity)
HLK66_RS02225	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HLK66_RS02235	ENOG4105C1J	atp-dependent rna helicase
HLK66_RS02240	ENOG410905X	membrane-flanked domain protein
HLK66_RS02245	ENOG4105CKV	Membrane
HLK66_RS02255	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HLK66_RS02260	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
HLK66_RS02275	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
HLK66_RS02280	ENOG4105FUA	antagonist
HLK66_RS02285	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HLK66_RS02290	ENOG4107SGM	protein serine threonine phosphatase
HLK66_RS02295	ENOG4105WN5	stage II sporulation protein
HLK66_RS02300	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HLK66_RS02310	ENOG41064BQ	Phosphatase
HLK66_RS02405	ENOG4105K8N	protein family UPF0079, ATPase
HLK66_RS02410	ENOG41072GX	Peptidase M22 Glycoprotease
HLK66_RS02415	ENOG410801F	ribosomal-protein-alanine acetyltransferase
HLK66_RS02420	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLK66_RS02425	ENOG4105C5H	ABC transporter
HLK66_RS02430	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLK66_RS02435	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
HLK66_RS02445	ENOG4108TYN	CAAX amino terminal protease family protein
HLK66_RS02450	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HLK66_RS02455	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HLK66_RS02460	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLK66_RS02490	ENOG4108YRF	PTS System
HLK66_RS02495	ENOG4105DM4	PTS System
HLK66_RS02500	ENOG4105DM4	PTS System
HLK66_RS02505	ENOG4105UP7	3-epimerase
HLK66_RS02510	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HLK66_RS02525	ENOG4105ETZ	PTS System
HLK66_RS02530	ENOG4105F3R	pts system mannose fructose sorbose family iid
HLK66_RS02535	ENOG4105D9R	oxidoreductase
HLK66_RS02540	ENOG4105CN5	Metallo-Beta-Lactamase
HLK66_RS02545	ENOG4105QE3	oxidoreductase
HLK66_RS02560	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS02565	ENOG4105C8J	)-transporter
HLK66_RS02580	ENOG4108MRH	transcriptional regulatory protein
HLK66_RS02585	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HLK66_RS02600	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HLK66_RS02615	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS02620	ENOG4107SSZ	Phosphatase
HLK66_RS02625	ENOG4105F6S	Spore photoproduct lyase
HLK66_RS02640	ENOG410606W	general stress protein
HLK66_RS02650	ENOG4105E5J	UV damage endonuclease
HLK66_RS02660	ENOG4105E5W	Transporter
HLK66_RS02670	ENOG4108KAM	Transcriptional regulator
HLK66_RS02675	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HLK66_RS02695	ENOG4105FDP	GntR family transcriptional regulator
HLK66_RS02700	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
HLK66_RS02705	ENOG4107Y7Q	pfkb domain protein
HLK66_RS02710	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HLK66_RS02730	ENOG4108KPW	sugar kinase
HLK66_RS02740	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HLK66_RS02750	ENOG4105D2H	Uronic isomerase
HLK66_RS02760	ENOG4105C5Y	PTS System
HLK66_RS02765	ENOG4105CS2	ec 3.2.1.21
HLK66_RS02770	ENOG4105CID	antiterminator
HLK66_RS02780	ENOG4106FN3	tellurium resistance protein
HLK66_RS02785	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HLK66_RS02800	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HLK66_RS02805	ENOG4105HF0	Membrane
HLK66_RS02810	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HLK66_RS02820	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HLK66_RS02825	ENOG4105C7N	Xanthine uracil vitamin C permease
HLK66_RS02830	ENOG4105CID	antiterminator
HLK66_RS02855	ENOG4105FQP	Beta-lactamase
HLK66_RS02910	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HLK66_RS02915	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HLK66_RS02920	ENOG4105C83	adenylosuccinate lyase
HLK66_RS02925	ENOG4105C8V	SAICAR synthetase
HLK66_RS02930	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
HLK66_RS02935	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
HLK66_RS02940	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
HLK66_RS02950	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HLK66_RS02955	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HLK66_RS02960	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HLK66_RS02965	ENOG4105C12	Phosphoribosylglycinamide synthetase
HLK66_RS02970	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLK66_RS02985	ENOG4108R5T	secreted protein
HLK66_RS02990	ENOG4105KGF	protein, YerC YecD
HLK66_RS02995	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
HLK66_RS03000	ENOG4105C4R	Atp-dependent dna helicase
HLK66_RS03005	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HLK66_RS03025	ENOG4105K56	Transcriptional regulator
HLK66_RS03035	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HLK66_RS03040	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HLK66_RS03045	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HLK66_RS03055	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HLK66_RS03065	ENOG4105DU6	RNA polymerase
HLK66_RS03085	ENOG4105CBD	Diacylglycerol kinase
HLK66_RS03120	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HLK66_RS03125	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
HLK66_RS03140	ENOG4108D32	Methyltransferase
HLK66_RS03155	ENOG4105DHI	Methyltransferase
HLK66_RS03170	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HLK66_RS03175	ENOG4105C4R	Atp-dependent dna helicase
HLK66_RS03185	ENOG4107QPV	Serine Threonine protein kinase
HLK66_RS03195	ENOG4108RWP	Major Facilitator Superfamily protein
HLK66_RS03200	ENOG4105CB2	alcohol dehydrogenase
HLK66_RS03215	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HLK66_RS03230	ENOG4108W0I	acetyltransferase
HLK66_RS03235	ENOG41069ER	domain protein
HLK66_RS03255	ENOG4105C2F	Histidine kinase
HLK66_RS03270	ENOG4105BZU	Histidine kinase
HLK66_RS03285	ENOG4105KVH	Transcriptional regulator
HLK66_RS03290	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLK66_RS03295	ENOG4106SCS	STAS domain
HLK66_RS03305	ENOG4105G6Z	alkaline phosphatase
HLK66_RS03315	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS03320	ENOG41063PX	domain protein
HLK66_RS03330	ENOG4105DY9	regulatoR
HLK66_RS03350	ENOG4105K7K	Transcriptional regulator
HLK66_RS03390	ENOG4105BZ1	(ABC) transporter
HLK66_RS03405	ENOG4105CX6	glutaminyL-tRNA synthetase
HLK66_RS03415	ENOG4108UMN	azlc family
HLK66_RS03430	ENOG4105CFH	Aspartokinase
HLK66_RS03440	ENOG4105E5Q	amino acid AbC transporter
HLK66_RS03445	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS03465	ENOG4105C3U	ABC transporter
HLK66_RS03470	ENOG4108JQ7	(ABC) transporter
HLK66_RS03480	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS03490	ENOG4105BZ1	(ABC) transporter
HLK66_RS03495	ENOG4105BZ1	(ABC) transporter
HLK66_RS03505	ENOG4105FDU	atp-dependent rna helicase
HLK66_RS03525	ENOG4105E1K	spore germination protein
HLK66_RS03555	ENOG4105ENE	Histidine kinase
HLK66_RS03560	ENOG4105WH1	Two component transcriptional regulator luxr family
HLK66_RS03585	ENOG4108S4H	thioesterase Superfamily protein
HLK66_RS03595	ENOG4106I4J	membrane
HLK66_RS03605	ENOG410855V	Acylphosphatase
HLK66_RS03620	ENOG4107URF	beta-phospho-glucomutase
HLK66_RS03625	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLK66_RS03640	ENOG4105E14	MotA TolQ exbB proton channel
HLK66_RS03645	ENOG4105ER2	Ompa motb domain protein
HLK66_RS03650	ENOG4108RS6	transposase
HLK66_RS03655	ENOG4105DD7	kinase (PfkB family
HLK66_RS03660	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HLK66_RS03680	ENOG4108IMY	Transcriptional regulator
HLK66_RS03685	ENOG4107414	GntR family transcriptional regulator
HLK66_RS03695	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLK66_RS03700	ENOG41068PA	UPF0435 protein
HLK66_RS03705	ENOG4105KJF	protein tyrosine phosphatase
HLK66_RS03715	ENOG4107U9T	Pfam:Ribonuclease_BN
HLK66_RS03720	ENOG4105C59	p-type ATPase
HLK66_RS03725	ENOG4108ISG	Major Facilitator
HLK66_RS03730	ENOG4105UPD	Calcium Proton
HLK66_RS03810	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HLK66_RS03815	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HLK66_RS03880	ENOG4105ENA	helicase
HLK66_RS03970	ENOG4105C5H	ABC transporter
HLK66_RS03975	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HLK66_RS03985	ENOG4105CGH	5'-nucleotidase
HLK66_RS03990	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HLK66_RS04005	ENOG4105BZU	Histidine kinase
HLK66_RS04030	ENOG4105BZU	Histidine kinase
HLK66_RS04050	ENOG4108W15	Protein of unknown function (DUF1456)
HLK66_RS04060	ENOG4107RSM	transcriptional regulator
HLK66_RS04070	ENOG4105IIP	Membrane
HLK66_RS04085	ENOG4108IJ8	ABC transporter
HLK66_RS04090	ENOG4105E90	ABC transporter
HLK66_RS04110	ENOG4105C8U	phosphate abc transporter
HLK66_RS04115	ENOG4105E2Z	phosphate ABC transporter (Permease
HLK66_RS04140	ENOG4105EQD	regulatoR
HLK66_RS04145	ENOG4105DFW	ABC transporter
HLK66_RS04150	ENOG4105C2J	ABC transporter
HLK66_RS04155	ENOG4108HWW	ABC transporter
HLK66_RS04160	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HLK66_RS04185	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLK66_RS04195	ENOG4105ECR	NmrA family
HLK66_RS04200	ENOG4105KVH	Transcriptional regulator
HLK66_RS04210	ENOG4105E5Q	amino acid AbC transporter
HLK66_RS04245	ENOG4105BZU	Histidine kinase
HLK66_RS04250	ENOG4105CNG	UPF0061 protein
HLK66_RS04255	ENOG4105DQX	Zinc finger domain
HLK66_RS04260	ENOG4108WV1	Pfam:DUF477
HLK66_RS04300	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HLK66_RS04305	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HLK66_RS04310	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLK66_RS04315	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLK66_RS04320	ENOG4108AEY	RNA polymerase sigma factor
HLK66_RS04325	ENOG4105J37	
HLK66_RS04335	ENOG4105BZ1	(ABC) transporter
HLK66_RS04340	ENOG4105BZ1	(ABC) transporter
HLK66_RS04365	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS04375	ENOG4105C6X	Major Facilitator
HLK66_RS04380	ENOG410746C	Acid-soluble spore protein O
HLK66_RS04390	ENOG4108HRK	Histidine kinase
HLK66_RS04395	ENOG4105DY9	regulatoR
HLK66_RS04400	ENOG4105FCD	Major Facilitator
HLK66_RS04410	ENOG4105CDW	Resistance protein
HLK66_RS04415	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HLK66_RS04420	ENOG410807C	QueT transporter
HLK66_RS04430	ENOG4105C19	ABC transporter
HLK66_RS04435	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK66_RS04445	ENOG4105BZU	Histidine kinase
HLK66_RS04450	ENOG4108S4H	thioesterase Superfamily protein
HLK66_RS04460	ENOG4105CP9	extracellular ligand-binding receptor
HLK66_RS04465	ENOG4105C32	Amino acid ABC transporter (Permease)
HLK66_RS04470	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HLK66_RS04475	ENOG4105C0Z	ABC transporter
HLK66_RS04480	ENOG4108IV0	ABC, transporter
HLK66_RS04485	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HLK66_RS04490	ENOG4106Z5D	Glycoside Hydrolase Family 43
HLK66_RS04500	ENOG410902V	Modulates RecA activity (By similarity)
HLK66_RS04510	ENOG4105XHU	Acid-soluble spore protein K
HLK66_RS04520	ENOG41067AE	Membrane-bound metal-dependent hydrolase
HLK66_RS04525	ENOG4105CEN	a g-specific adenine glycosylase
HLK66_RS04530	ENOG4106BXE	
HLK66_RS04535	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
HLK66_RS04555	ENOG4105BZ1	(ABC) transporter
HLK66_RS04560	ENOG4107NBY	Membrane
HLK66_RS04565	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HLK66_RS04575	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLK66_RS04580	ENOG4105G5W	regulator Fur family
HLK66_RS04790	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK66_RS04795	ENOG4108SWU	Histidine kinase
HLK66_RS04810	ENOG4105BZ1	(ABC) transporter
HLK66_RS04830	ENOG4105VCP	PTS System
HLK66_RS04845	ENOG4105CK1	PTS System
HLK66_RS04850	ENOG4105CS2	ec 3.2.1.21
HLK66_RS04855	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS04895	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HLK66_RS04910	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HLK66_RS04935	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS04940	ENOG4108MEK	Metal-binding protein YodA
HLK66_RS04945	ENOG4105DSE	periplasmic solute binding protein
HLK66_RS04945	ENOG4105DSE	periplasmic solute binding protein
HLK66_RS04965	ENOG4105RHY	Pfam:UPF0157
HLK66_RS04975	ENOG4108IPJ	Membrane
HLK66_RS04985	ENOG4108MES	Periplasmic binding protein
HLK66_RS04990	ENOG4105DQ5	transport system permease protein
HLK66_RS04995	ENOG4108IHU	transport system permease protein
HLK66_RS05000	ENOG4105E0A	ABC, transporter
HLK66_RS05005	ENOG4105F5H	Glycosyl Hydrolase Family 88
HLK66_RS05035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HLK66_RS05040	ENOG4105CID	antiterminator
HLK66_RS05045	ENOG4105C5Y	PTS System
HLK66_RS05050	ENOG4105CS2	ec 3.2.1.21
HLK66_RS05055	ENOG4105P4J	Allophanate hydrolase, subunit 1
HLK66_RS05065	ENOG4105C2C	drug resistance transporter, Bcr CflA
HLK66_RS05070	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HLK66_RS05080	ENOG4105D2N	Aldolase
HLK66_RS05085	ENOG4105E98	transcriptional regulator DeoR family
HLK66_RS05090	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HLK66_RS05100	ENOG4105BZ1	(ABC) transporter
HLK66_RS05105	ENOG4105C4X	radical SAM domain protein
HLK66_RS05115	ENOG4105CS2	ec 3.2.1.21
HLK66_RS05170	ENOG41090MY	MarR family Transcriptional regulator
HLK66_RS05175	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
HLK66_RS05180	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HLK66_RS05185	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
HLK66_RS05190	ENOG4105FBA	Phospholipase Carboxylesterase
HLK66_RS05205	ENOG4105CUC	YeeE YedE family protein
HLK66_RS05215	ENOG4108XFG	YwhD family
HLK66_RS05225	ENOG4107V0Z	fmn reductase
HLK66_RS05240	ENOG4105C2F	Histidine kinase
HLK66_RS05245	ENOG4105EQD	regulatoR
HLK66_RS05250	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS05255	ENOG4107QNK	)-transporter
HLK66_RS05275	ENOG4105C6T	cysteine synthase
HLK66_RS05290	ENOG4105EMU	Dehydrogenase
HLK66_RS05315	ENOG4108Z8I	decarboxylase
HLK66_RS05325	ENOG4107ZTW	SNARE associated Golgi
HLK66_RS05355	ENOG4105E2A	Dehydrogenase
HLK66_RS05370	ENOG4108QTI	)-transporter
HLK66_RS05375	ENOG4105CNH	Multidrug resistance protein MdtL
HLK66_RS05390	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HLK66_RS05405	ENOG4108DBC	nitroreductase
HLK66_RS05410	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HLK66_RS05415	ENOG4105CYN	Serine protein kinase
HLK66_RS05450	ENOG4105WD1	Membrane
HLK66_RS05465	ENOG4105CPC	Aldo Keto reductase
HLK66_RS05475	ENOG4108Q3X	Transcriptional regulator
HLK66_RS05480	ENOG4105CS2	ec 3.2.1.21
HLK66_RS05485	ENOG4105C5Y	PTS System
HLK66_RS05490	ENOG4105C4X	radical SAM domain protein
HLK66_RS05510	ENOG4105E6M	Sulphatase-modifying factor protein
HLK66_RS05520	ENOG4105ID8	Transcriptional regulator, ARAC family
HLK66_RS05525	ENOG4105C5Y	PTS System
HLK66_RS05530	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HLK66_RS05580	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLK66_RS05590	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HLK66_RS05610	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
HLK66_RS05615	ENOG4106AXJ	AraC family transcriptional regulator
HLK66_RS05620	ENOG410631K	Membrane
HLK66_RS05625	ENOG4105UNS	Pfam:DUF419
HLK66_RS05630	ENOG41075H3	AraC family transcriptional regulator
HLK66_RS05635	ENOG4105CT4	transporter
HLK66_RS05640	ENOG4105CNT	hydrolase family 2
HLK66_RS05650	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HLK66_RS05655	ENOG4105DMW	Dehydrogenase reductase
HLK66_RS05660	ENOG4105JQZ	Methyltransferase
HLK66_RS05670	ENOG4108S01	response regulator
HLK66_RS05675	ENOG4108ZGX	Histidine kinase
HLK66_RS05680	ENOG4105ECK	Fatty Acid Desaturase
HLK66_RS05685	ENOG4105C22	threonyL-tRNA synthetase
HLK66_RS05695	ENOG4108IMY	Transcriptional regulator
HLK66_RS05710	ENOG4105II7	pyrroline-5-carboxylate reductase
HLK66_RS05735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS05740	ENOG4105BZU	Histidine kinase
HLK66_RS05745	ENOG4108JYZ	YitT family
HLK66_RS05750	ENOG4105CJ3	phosphate transporter
HLK66_RS05755	ENOG4107GRR	phosphate transport regulator
HLK66_RS05765	ENOG4105E1F	short-chain dehydrogenase reductase
HLK66_RS05775	ENOG4107BMA	Transglycosylase associated protein
HLK66_RS05780	ENOG4108YBP	pseudouridine synthase
HLK66_RS05800	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HLK66_RS05825	ENOG4105C7N	Xanthine uracil vitamin C permease
HLK66_RS05840	ENOG4108KSA	LysR family transcriptional regulator
HLK66_RS05845	ENOG4105KBX	Transcriptional regulator, TetR family
HLK66_RS05850	ENOG4105KPY	Small multidrug resistance protein
HLK66_RS05855	ENOG4105RXJ	
HLK66_RS05875	ENOG4105D29	Helix-turn-helix type 11 domain protein
HLK66_RS05935	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
HLK66_RS05945	ENOG4108Z5V	transcriptional regulator, merr family
HLK66_RS05950	ENOG4108UQV	Membrane
HLK66_RS05955	ENOG4108TU7	Inherit from COG: (ABC) transporter
HLK66_RS05960	ENOG4105CJ1	ABC, transporter
HLK66_RS05970	ENOG4108JYZ	YitT family
HLK66_RS05975	ENOG4105D7N	magnesium and cobalt transport protein CorA
HLK66_RS05980	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS05985	ENOG4105C37	(CBS) domain
HLK66_RS05990	ENOG4105C37	(CBS) domain
HLK66_RS06000	ENOG4105EC8	Methyl-accepting chemotaxis
HLK66_RS06025	ENOG4105BZ1	(ABC) transporter
HLK66_RS06030	ENOG4105BZ1	(ABC) transporter
HLK66_RS06035	ENOG4105NIV	Esterase
HLK66_RS06040	ENOG410874W	AraC family transcriptional regulator
HLK66_RS06070	ENOG4108SA1	esterase
HLK66_RS06115	ENOG410839P	
HLK66_RS06120	ENOG410839P	
HLK66_RS06135	ENOG4105WZB	UPF0342 protein
HLK66_RS06140	ENOG4105YWU	small acid-soluble spore protein
HLK66_RS06150	ENOG4105D4P	Coproporphyrinogen iii oxidase
HLK66_RS06155	ENOG4105C7N	Xanthine uracil vitamin C permease
HLK66_RS06160	ENOG4108IUX	(ABC) transporter
HLK66_RS06165	ENOG4105RHA	ABC transporter, permease
HLK66_RS06170	ENOG4107VRP	DNA repair exonuclease
HLK66_RS06175	ENOG4106D4I	domain protein
HLK66_RS06220	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HLK66_RS06225	ENOG4105K59	histidine triad (HIT) protein
HLK66_RS06265	ENOG4105ENE	Histidine kinase
HLK66_RS06270	ENOG4105WH1	Two component transcriptional regulator luxr family
HLK66_RS06280	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HLK66_RS06285	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HLK66_RS06295	ENOG4105ECB	domain protein
HLK66_RS06300	ENOG4105DF9	Lipoate-protein, ligase
HLK66_RS06305	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HLK66_RS06335	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HLK66_RS06340	ENOG4108RCF	TRANSCRIPTIONal
HLK66_RS06360	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HLK66_RS06400	ENOG4105ERH	Fumarylacetoacetate hydrolase
HLK66_RS06405	ENOG4105YHS	UPF0344 protein
HLK66_RS06410	ENOG4105BZU	Histidine kinase
HLK66_RS06415	ENOG4105WH1	Two component transcriptional regulator luxr family
HLK66_RS06420	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
HLK66_RS06425	ENOG4105C37	(CBS) domain
HLK66_RS06430	ENOG4105CJ1	ABC, transporter
HLK66_RS06445	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLK66_RS06460	ENOG4106KNT	transcriptional regulator
HLK66_RS06465	ENOG4105D9R	oxidoreductase
HLK66_RS06470	ENOG4105EE0	oxidoreductase
HLK66_RS06480	ENOG4105FTV	AraC Family Transcriptional Regulator
HLK66_RS06495	ENOG4105VRR	gCN5-related N-acetyltransferase
HLK66_RS06505	ENOG4105CAQ	asparagine synthetase
HLK66_RS06525	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLK66_RS06530	ENOG4108VPT	UPF0234 protein
HLK66_RS06540	ENOG4105QNR	S1 RNA binding domain protein
HLK66_RS06550	ENOG4105EPR	degv family
HLK66_RS06555	ENOG4107AYK	membrAne
HLK66_RS06565	ENOG41073B9	
HLK66_RS06575	ENOG4108KP7	hydrolase
HLK66_RS06580	ENOG4108MXZ	Esterase
HLK66_RS06585	ENOG4105VG1	fes assembly suf system protein
HLK66_RS06590	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLK66_RS06595	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HLK66_RS06600	ENOG4105DAA	L-lactate
HLK66_RS06605	ENOG4105JXH	GntR family transcriptional regulator
HLK66_RS06610	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HLK66_RS06615	ENOG4107QR9	Iron-sulfur cluster binding protein
HLK66_RS06620	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
HLK66_RS06625	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HLK66_RS06630	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HLK66_RS06635	ENOG4105CAS	nag kinase
HLK66_RS06655	ENOG4105DBV	ornithine carbamoyltransferase
HLK66_RS06665	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HLK66_RS06685	ENOG4107RMD	Basic membrane lipoprotein
HLK66_RS06690	ENOG4105CHR	reductase
HLK66_RS06695	ENOG4105ETD	TRANSCRIPTIONal
HLK66_RS06705	ENOG410787A	Pts system, glucitol sorbitol-specific
HLK66_RS06710	ENOG4105DZY	Pts system, glucitol sorbitol-specific
HLK66_RS06725	ENOG4108X4Q	Hydrolase
HLK66_RS06735	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HLK66_RS06740	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HLK66_RS06745	ENOG4105G5W	regulator Fur family
HLK66_RS06755	ENOG4108KU1	UPF0736 protein
HLK66_RS06760	ENOG4105C31	Tryptophanyl-tRNA synthetase
HLK66_RS06765	ENOG4108J59	Extracellular solute-binding protein, family 5
HLK66_RS06770	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS06775	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS06785	ENOG4108JQ7	(ABC) transporter
HLK66_RS06800	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
HLK66_RS06805	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLK66_RS06810	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK66_RS06820	ENOG4105DPN	Oligoendopeptidase f
HLK66_RS06825	ENOG4105T58	Dithiol-disulfide isomerase
HLK66_RS06830	ENOG4108Z18	K06886 hemoglobin
HLK66_RS06835	ENOG4105E4C	Lytic transglycosylase catalytic
HLK66_RS06840	ENOG4105MIX	Adenylate cyclase
HLK66_RS06860	ENOG4105EMS	pseudouridine synthase
HLK66_RS06865	ENOG4107S1Q	Phosphatase
HLK66_RS06870	ENOG4105CJW	magnesium transporter
HLK66_RS06880	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HLK66_RS06905	ENOG41090VF	Stage v sporulation protein ac
HLK66_RS06910	ENOG4105CZ3	stage V sporulation protein ad
HLK66_RS06930	ENOG4105ENA	helicase
HLK66_RS06940	ENOG4105H67	Protein of unknown function (DUF421)
HLK66_RS06950	ENOG4108ZMI	UPF0477 protein
HLK66_RS06960	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HLK66_RS06965	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HLK66_RS06975	ENOG4108UZX	fmn reductase
HLK66_RS06995	ENOG4108ZJ4	polysaccharide deacetylase
HLK66_RS07000	ENOG4105C6Z	Gluconate
HLK66_RS07025	ENOG4105CMG	Carbohydrate kinase
HLK66_RS07040	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HLK66_RS07045	ENOG4105CMR	udp-glucose 4-epimerase
HLK66_RS07050	ENOG4105CKN	UDP-glucose-hexose-1-phosphate uridylyltransferase
HLK66_RS07055	ENOG4105K64	Glycosyl transferase, family 2
HLK66_RS07065	ENOG4105CE4	GlcNAc 6-P deacetylase
HLK66_RS07070	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HLK66_RS07080	ENOG4105E7W	lamb ycsf family protein
HLK66_RS07090	ENOG4105DUX	Transporter
HLK66_RS07110	ENOG4105DJV	ribulose-phosphate 3-epimerase
HLK66_RS07120	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HLK66_RS07145	ENOG4107XVH	Transcriptional regulator
HLK66_RS07150	ENOG4105DET	Rhamnulokinase
HLK66_RS07155	ENOG4105DKG	l-rhamnose isomerase
HLK66_RS07175	ENOG4105C2F	Histidine kinase
HLK66_RS07195	ENOG4108HWW	ABC transporter
HLK66_RS07200	ENOG4105E98	transcriptional regulator DeoR family
HLK66_RS07215	ENOG4105CG3	alpha amylase, catalytic region
HLK66_RS07225	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HLK66_RS07230	ENOG41090R9	glycosyltransferase
HLK66_RS07240	ENOG4105FAW	cDP-glucose 4,6-dehydratase
HLK66_RS07260	ENOG4107S6X	Glycosyl transferase, family 2
HLK66_RS07270	ENOG41076HS	cation diffusion facilitator family transporter
HLK66_RS07275	ENOG410756H	nucleotidyltransferase
HLK66_RS07285	ENOG4107TUM	Amidinotransferase
HLK66_RS07295	ENOG4108IG5	Transcriptional regulator
HLK66_RS07300	ENOG4105CVA	phosphate
HLK66_RS07305	ENOG4108IUM	Glycogen debranching enzyme
HLK66_RS07315	ENOG4105C5W	Aldolase
HLK66_RS07320	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HLK66_RS07325	ENOG4105XTG	Pfam:DUF156
HLK66_RS07330	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
HLK66_RS07335	ENOG41085GJ	domain protein
HLK66_RS07370	ENOG4105WEF	catalase
HLK66_RS07415	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK66_RS07465	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HLK66_RS07470	ENOG4106YBV	Methyl-accepting chemotaxis
HLK66_RS07475	ENOG4108WS4	fmn reductase
HLK66_RS07480	ENOG4105EQD	regulatoR
HLK66_RS07485	ENOG4105C2F	Histidine kinase
HLK66_RS07530	ENOG4107RCC	Major Facilitator Superfamily
HLK66_RS07540	ENOG4105E2Y	ABC, transporter
HLK66_RS07545	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS07550	ENOG4105GVF	(ABC) transporter
HLK66_RS07560	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS07570	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS07580	ENOG4108HKT	sucrose-6-phosphate hydrolase
HLK66_RS07585	ENOG4105D7K	pfkb domain protein
HLK66_RS07590	ENOG4108HKT	sucrose-6-phosphate hydrolase
HLK66_RS07595	ENOG4108HKT	sucrose-6-phosphate hydrolase
HLK66_RS07600	ENOG4105EDQ	levansucrase EC 2.4.1.10
HLK66_RS07605	ENOG4105XN3	extracellular solute-binding protein family 1
HLK66_RS07610	ENOG4105EQD	regulatoR
HLK66_RS07615	ENOG4105C2F	Histidine kinase
HLK66_RS07625	ENOG4107R37	Glutamate dehydrogenase
HLK66_RS07630	ENOG4105DJB	Major Facilitator Superfamily
HLK66_RS07635	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HLK66_RS07650	ENOG4105CS2	ec 3.2.1.21
HLK66_RS07655	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HLK66_RS07660	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
HLK66_RS07665	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HLK66_RS07670	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
HLK66_RS07675	ENOG4107V9H	nitrite transporter
HLK66_RS07680	ENOG4108JUA	Transcriptional regulator
HLK66_RS07685	ENOG4105EA8	2-Nitropropane dioxygenase
HLK66_RS07695	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
HLK66_RS07720	ENOG4105CKI	cobalamin synthesis protein
HLK66_RS07725	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HLK66_RS07735	ENOG4105WYW	fructose-bisphosphate aldolase
HLK66_RS07765	ENOG4105C2X	Arabinose 5-phosphate isomerase
HLK66_RS07770	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLK66_RS07780	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HLK66_RS07785	ENOG4105ECQ	AraC Family Transcriptional Regulator
HLK66_RS07795	ENOG4105DRS	transport system, permease
HLK66_RS07805	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HLK66_RS07825	ENOG4107TYA	transient receptor potential locus
HLK66_RS07830	ENOG4105F0V	Cell wall hydrolase
HLK66_RS07840	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HLK66_RS07855	ENOG4108HQR	Glycine betaine
HLK66_RS07865	ENOG4105FTV	AraC Family Transcriptional Regulator
HLK66_RS07885	ENOG4105C4C	beta-galactosidase
HLK66_RS07890	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HLK66_RS07895	ENOG4105F0V	Cell wall hydrolase
HLK66_RS07905	ENOG4107HP6	Transcriptional regulator
HLK66_RS07910	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLK66_RS07915	ENOG4105C01	Dihydroxy-acid dehydratase
HLK66_RS07925	ENOG4105DSG	hydrolase family 43
HLK66_RS07940	ENOG41090KR	LysR family transcriptional Regulator
HLK66_RS07960	ENOG4108IJ9	(ABC) transporter
HLK66_RS07975	ENOG4105BZ7	extracellular solute-binding protein family 1
HLK66_RS07980	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLK66_RS07985	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HLK66_RS08000	ENOG4105CTB	Polyprenyl synthetase
HLK66_RS08005	ENOG4108RQ5	Beta-lactamase domain-containing protein
HLK66_RS08025	ENOG4105CHR	reductase
HLK66_RS08035	ENOG4105G9B	Transcriptional regulator
HLK66_RS08040	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HLK66_RS08060	ENOG4108TYN	CAAX amino terminal protease family protein
HLK66_RS08065	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HLK66_RS08070	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HLK66_RS08075	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HLK66_RS08080	ENOG4105EUJ	GTP cyclohydrolase i
HLK66_RS08085	ENOG4107R6U	sodium dicarboxylate symporter
HLK66_RS08090	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HLK66_RS08115	ENOG4107V0Z	fmn reductase
HLK66_RS08130	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HLK66_RS08135	ENOG4106Z5D	Glycoside Hydrolase Family 43
HLK66_RS08140	ENOG4105MU9	integral membrane protein
HLK66_RS08145	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
HLK66_RS08155	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HLK66_RS08160	ENOG4107S2N	Type III effector Hrp-dependent
HLK66_RS08165	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HLK66_RS08170	ENOG4106R3P	AraC family transcriptional regulator
HLK66_RS08180	ENOG4105C94	Transporter
HLK66_RS08195	ENOG4105DAP	Nicotinate phosphoribosyltransferase
HLK66_RS08200	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HLK66_RS08205	ENOG4108JQ1	Dehydrogenase
HLK66_RS08215	ENOG4105C85	amino acid
HLK66_RS08220	ENOG4108IUW	ABC transporter
HLK66_RS08255	ENOG4105BZU	Histidine kinase
HLK66_RS08260	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HLK66_RS08270	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HLK66_RS08280	ENOG4105C26	Dehydrogenase
HLK66_RS08285	ENOG4105JVQ	RNA Polymerase
HLK66_RS08310	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS08315	ENOG4105CG3	alpha amylase, catalytic region
HLK66_RS08320	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HLK66_RS08325	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HLK66_RS08330	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HLK66_RS08340	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
HLK66_RS08345	ENOG4105MU9	integral membrane protein
HLK66_RS08360	ENOG4105C2F	Histidine kinase
HLK66_RS08365	ENOG4105EQD	regulatoR
HLK66_RS08370	ENOG4105EP8	Glycosyl Hydrolase Family 88
HLK66_RS08395	ENOG4107FCW	Abortive infection protein
HLK66_RS08420	ENOG4105E35	Dipicolinate synthase subunit A
HLK66_RS08435	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HLK66_RS08440	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
HLK66_RS08445	ENOG4105CK5	oxidoreductase
HLK66_RS08450	ENOG4105DSE	periplasmic solute binding protein
HLK66_RS08465	ENOG4105EMN	RNA polymerase sigma factor
HLK66_RS08475	ENOG4105CNI	cell division protein FtsW
HLK66_RS08485	ENOG4105F04	LysR family Transcriptional regulator
HLK66_RS08495	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS08510	ENOG4108HGU	Histidine kinase
HLK66_RS08525	ENOG4108Q5U	germination protein, ger(x)c family
HLK66_RS08530	ENOG4107Y03	Nitroreductase
HLK66_RS08535	ENOG4105HDK	L-asparaginase
HLK66_RS08545	ENOG4107VFR	oxidoreductase
HLK66_RS08550	ENOG4105Z8B	NlpC/P60 family
HLK66_RS08555	ENOG4105DIK	(ABC) transporter
HLK66_RS08580	ENOG4105D5T	phosphonate abc transporter
HLK66_RS08590	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HLK66_RS08600	ENOG4105KRI	phosphocarrier protein (HPr
HLK66_RS08605	ENOG4105DKW	ABC transporter
HLK66_RS08610	ENOG4108X4Q	Hydrolase
HLK66_RS08625	ENOG4105DZ6	Band 7 protein
HLK66_RS08635	ENOG4107SQ8	Glycine betaine
HLK66_RS08640	ENOG4108IJ7	Glycine betaine
HLK66_RS08645	ENOG4105TRT	Transcriptional regulator
HLK66_RS08660	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HLK66_RS08665	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HLK66_RS08670	ENOG4107QXX	ABC transporter
HLK66_RS08675	ENOG4105EZ7	amino acid ABC transporter
HLK66_RS08685	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS08695	ENOG4107TS3	membrane protein, TerC
HLK66_RS08700	ENOG410681C	small acid-soluble spore protein
HLK66_RS08720	ENOG4108TGC	Acyltransferase
HLK66_RS08725	ENOG4105BZU	Histidine kinase
HLK66_RS08735	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HLK66_RS08750	ENOG4105BZU	Histidine kinase
HLK66_RS08755	ENOG41090MY	MarR family Transcriptional regulator
HLK66_RS08770	ENOG4108K88	Membrane
HLK66_RS08800	ENOG4105KRI	phosphocarrier protein (HPr
HLK66_RS08805	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HLK66_RS08810	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HLK66_RS08815	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HLK66_RS08820	ENOG4105CHM	Aminotransferase
HLK66_RS08840	ENOG4107R88	Chemotaxis protein (CheV)
HLK66_RS08850	ENOG4105UIN	
HLK66_RS08855	ENOG4105BZU	Histidine kinase
HLK66_RS08865	ENOG4105EPM	Diguanylate phosphodiesterase
HLK66_RS08880	ENOG4107IN1	Protein of unknown function (DUF1797)
HLK66_RS08895	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HLK66_RS08905	ENOG4105D8X	mechanosensitive ion channel
HLK66_RS08920	ENOG4107R19	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLK66_RS08925	ENOG4107ZYR	domain protein
HLK66_RS08930	ENOG4108RS6	transposase
HLK66_RS08935	ENOG4105CN5	Metallo-Beta-Lactamase
HLK66_RS08960	ENOG4105CPP	Dehydrogenase, E1 component
HLK66_RS08965	ENOG4105C7S	Dehydrogenase
HLK66_RS08985	ENOG4105CXN	decarboxylase
HLK66_RS08995	ENOG4108WQ8	UPF0637 protein
HLK66_RS09005	ENOG4105ECY	inositol monophosphatase
HLK66_RS09010	ENOG4105CI3	gtp-binding protein typa
HLK66_RS09030	ENOG4108IAB	Phoh family
HLK66_RS09045	ENOG4105CNI	cell division protein FtsW
HLK66_RS09050	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HLK66_RS09060	ENOG4106UY4	Inherit from COG: Scp-like extracellular
HLK66_RS09090	ENOG4106H78	methyltransferase
HLK66_RS09095	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HLK66_RS09100	ENOG4105H20	Sporulation integral membrane protein YlbJ
HLK66_RS09105	ENOG4105D78	K07001 NTE family protein
HLK66_RS09110	ENOG4105CDE	UPF0348 protein
HLK66_RS09115	ENOG4105KNH	Nucleic acid-binding protein
HLK66_RS09125	ENOG4105EWC	Purine nucleoside phosphorylase
HLK66_RS09145	ENOG41074B2	UPF0747 protein
HLK66_RS09150	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS09155	ENOG4108V6E	Cell division protein mraZ
HLK66_RS09170	ENOG4105CJN	penicillin-binding protein
HLK66_RS09180	ENOG4105CJN	penicillin-binding protein
HLK66_RS09185	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HLK66_RS09195	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HLK66_RS09200	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HLK66_RS09205	ENOG4105CNI	cell division protein FtsW
HLK66_RS09210	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HLK66_RS09215	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
HLK66_RS09220	ENOG4108R2U	division initiation protein
HLK66_RS09230	ENOG4105K67	small basic protein
HLK66_RS09235	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HLK66_RS09240	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HLK66_RS09245	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS09250	ENOG4105FFI	sigma-e processing peptidase spoiiga
HLK66_RS09255	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK66_RS09265	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HLK66_RS09270	ENOG4105DFA	alanine racemase domain protein
HLK66_RS09275	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
HLK66_RS09280	ENOG41067XK	integral membrane protein
HLK66_RS09285	ENOG4105DBK	s4 domain protein
HLK66_RS09295	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HLK66_RS09300	ENOG4105SCY	DNAK suppressor
HLK66_RS09305	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HLK66_RS09310	ENOG4105C34	Pseudouridine synthase
HLK66_RS09315	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HLK66_RS09325	ENOG4105CXT	aspartate transcarbamylase
HLK66_RS09340	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HLK66_RS09350	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HLK66_RS09375	ENOG4105DSJ	YicC domain protein
HLK66_RS09380	ENOG4105KC4	UPF0296 protein
HLK66_RS09385	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HLK66_RS09395	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HLK66_RS09400	ENOG4105C25	Primosomal protein n'
HLK66_RS09420	ENOG4105EG2	ABC transporter, permease
HLK66_RS09445	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HLK66_RS09450	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HLK66_RS09455	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLK66_RS09460	ENOG4108ZF3	Phosphatase
HLK66_RS09465	ENOG4105D9P	serine threonine protein kinase
HLK66_RS09470	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HLK66_RS09475	ENOG4105FJ0	thiamine
HLK66_RS09485	ENOG4105VB9	50S ribosomal protein l28
HLK66_RS09490	ENOG4108ZAA	Alkaline-shock protein
HLK66_RS09495	ENOG4105DP4	dak2 domain fusion protein ylov
HLK66_RS09505	ENOG4105EJQ	L-serine dehydratase
HLK66_RS09515	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
HLK66_RS09520	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HLK66_RS09525	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HLK66_RS09530	ENOG4105CHR	reductase
HLK66_RS09535	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HLK66_RS09540	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HLK66_RS09545	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HLK66_RS09550	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLK66_RS09565	ENOG4105CJ1	ABC, transporter
HLK66_RS09580	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HLK66_RS09610	ENOG4105K5M	30s ribosomal protein S16
HLK66_RS09615	ENOG4105VB6	UPF0109 protein
HLK66_RS09625	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HLK66_RS09630	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HLK66_RS09640	ENOG4105C3F	Signal peptidase i
HLK66_RS09645	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HLK66_RS09660	ENOG4105D00	flagellar biosynthetic protein flhB
HLK66_RS09665	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HLK66_RS09670	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HLK66_RS09675	ENOG4105C79	DNA protecting protein DprA
HLK66_RS09680	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HLK66_RS09685	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS09690	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HLK66_RS09695	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HLK66_RS09700	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
HLK66_RS09705	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HLK66_RS09710	ENOG4108ZC9	flagellar basal-body rod protein flgc
HLK66_RS09715	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HLK66_RS09720	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HLK66_RS09725	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HLK66_RS09740	ENOG4106YF4	Flagellar biosynthesis chaperone
HLK66_RS09755	ENOG410822I	Flagellar hook capping protein
HLK66_RS09765	ENOG4108JQA	flagellar
HLK66_RS09770	ENOG41068WV	flagellar FlbD family protein
HLK66_RS09780	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HLK66_RS09785	ENOG4105DD5	Flagellar motor switch protein
HLK66_RS09790	ENOG4107YTP	response regulator receiver protein
HLK66_RS09800	ENOG4105CN7	Flagellar biosynthetic protein FliP
HLK66_RS09805	ENOG4105VS8	Flagellar biosynthetic protein fliq
HLK66_RS09810	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HLK66_RS09815	ENOG4105D00	flagellar biosynthetic protein flhB
HLK66_RS09820	ENOG4105D7B	Flagellar biosynthesis protein flha
HLK66_RS09825	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HLK66_RS09835	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HLK66_RS09840	ENOG4105CBS	Chea signal transduction histidine kinase
HLK66_RS09845	ENOG410807Z	Modulation of CheA activity in response to attractants (Chemotaxis
HLK66_RS09855	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HLK66_RS09860	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK66_RS09875	ENOG4105CE9	30S ribosomal protein S2
HLK66_RS09885	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HLK66_RS09890	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HLK66_RS09900	ENOG4105KNE	Phosphatidate cytidylyltransferase
HLK66_RS09905	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HLK66_RS09910	ENOG4105DZP	Membrane-associated zinc metalloprotease
HLK66_RS09915	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HLK66_RS09920	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HLK66_RS09925	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HLK66_RS09930	ENOG4105CHV	Transcription elongation factor NusA
HLK66_RS09935	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
HLK66_RS09940	ENOG4105VHM	ribosomal protein
HLK66_RS09945	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HLK66_RS09950	ENOG4105W7A	Protein of unknown function (DUF503)
HLK66_RS09960	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HLK66_RS09965	ENOG4105DTN	riboflavin biosynthesis protein ribF
HLK66_RS09970	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HLK66_RS09975	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HLK66_RS09985	ENOG4105C1V	Peptidase, M16
HLK66_RS09990	ENOG4105E35	Dipicolinate synthase subunit A
HLK66_RS09995	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
HLK66_RS10000	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HLK66_RS10010	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HLK66_RS10025	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
HLK66_RS10040	ENOG4105CNU	cell division protein FtsK
HLK66_RS10045	ENOG4105FDP	GntR family transcriptional regulator
HLK66_RS10050	ENOG4105DIH	basic membrane
HLK66_RS10055	ENOG4108JQ9	ABC transporter
HLK66_RS10060	ENOG4105UIB	(ABC) transporter
HLK66_RS10090	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
HLK66_RS10095	ENOG4105XZV	Protein of unknown function (DUF3243)
HLK66_RS10110	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HLK66_RS10115	ENOG4105CEV	competence damage-inducible protein
HLK66_RS10120	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HLK66_RS10125	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HLK66_RS10130	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS10135	ENOG4105D48	metallophosphoesterase
HLK66_RS10140	ENOG4105MCT	stage V sporulation protein S
HLK66_RS10145	ENOG4108IGT	Dipeptidase
HLK66_RS10150	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HLK66_RS10160	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS10185	ENOG4105X3H	Excalibur domain protein
HLK66_RS10190	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HLK66_RS10195	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HLK66_RS10210	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS10225	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS10230	ENOG4105VCP	PTS System
HLK66_RS10265	ENOG4105EU9	
HLK66_RS10275	ENOG4107T5V	SNARE associated Golgi
HLK66_RS10290	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS10295	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS10305	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLK66_RS10310	ENOG4105DCM	major facilitator superfamily
HLK66_RS10315	ENOG410645S	MarR family Transcriptional regulator
HLK66_RS10355	ENOG4107Z3H	Transcriptional regulator, TetR family
HLK66_RS10360	ENOG4108VKI	Cell wall hydrolase
HLK66_RS10390	ENOG4105E09	nadh pyrophosphatase
HLK66_RS10395	ENOG4105C0X	amino acid
HLK66_RS10410	ENOG4108ZHR	arsR family transcriptional regulator
HLK66_RS10430	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HLK66_RS10440	ENOG4105CVK	Glutamate decarboxylase
HLK66_RS10445	ENOG4105CHR	reductase
HLK66_RS10455	ENOG4107RF6	penicillin-binding protein
HLK66_RS10460	ENOG4107RVG	penicillin-binding protein
HLK66_RS10465	ENOG4105NA0	Transcriptional regulator
HLK66_RS10510	ENOG4105FDP	GntR family transcriptional regulator
HLK66_RS10520	ENOG4105ETZ	PTS System
HLK66_RS10525	ENOG4105F3R	pts system mannose fructose sorbose family iid
HLK66_RS10530	ENOG4105DAS	pts system
HLK66_RS10535	ENOG4105EP8	Glycosyl Hydrolase Family 88
HLK66_RS10565	ENOG4105CHR	reductase
HLK66_RS10575	ENOG41086D8	Transcriptional regulator
HLK66_RS10580	ENOG41068WN	
HLK66_RS10620	ENOG41060YP	
HLK66_RS10670	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HLK66_RS10675	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HLK66_RS10680	ENOG4105CDY	transcriptional regulatory protein
HLK66_RS10690	ENOG4107TXC	Transcriptional regulator
HLK66_RS10730	ENOG4105CRK	lysyL-tRNA synthetase
HLK66_RS10740	ENOG4108UYN	gCN5-related N-acetyltransferase
HLK66_RS10780	ENOG4108XET	gCN5-related N-acetyltransferase
HLK66_RS10800	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
HLK66_RS10805	ENOG4108J2P	Alpha beta hydrolase fold
HLK66_RS10820	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS10850	ENOG4105WAB	arsR family transcriptional regulator
HLK66_RS10865	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HLK66_RS10875	ENOG4108IND	Tetr family transcriptional regulator
HLK66_RS10880	ENOG4105EQ0	Major Facilitator superfamily
HLK66_RS10900	ENOG4105BZU	Histidine kinase
HLK66_RS10985	ENOG41086D8	Transcriptional regulator
HLK66_RS11000	ENOG4105C75	arginyL-tRNA synthetase
HLK66_RS11005	ENOG4105KTB	nuclear export factor GLE1
HLK66_RS11025	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLK66_RS11030	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HLK66_RS11090	ENOG4105DXX	methyltransferase
HLK66_RS11125	ENOG4108JUA	Transcriptional regulator
HLK66_RS11130	ENOG4107RUY	(E1 component), alpha subunit
HLK66_RS11140	ENOG4107QKR	Dehydrogenase
HLK66_RS11150	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HLK66_RS11180	ENOG4105VMP	Transcriptional regulator
HLK66_RS11185	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HLK66_RS11200	ENOG4108TWJ	NADH dehydrogenase subunit 5
HLK66_RS11215	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
HLK66_RS11270	ENOG41080TC	multidrug resistance protein
HLK66_RS11275	ENOG4108RZE	Tetr family transcriptional regulator
HLK66_RS11320	ENOG4105EGI	Transcriptional regulator
HLK66_RS11370	ENOG4105BZU	Histidine kinase
HLK66_RS11425	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HLK66_RS11465	ENOG410870W	N-acetyltransferase
HLK66_RS11485	ENOG4108IYU	L-aspartate oxidase
HLK66_RS11490	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HLK66_RS11495	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HLK66_RS11505	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HLK66_RS11515	ENOG4106F1P	AAA ATPase, central domain protein
HLK66_RS11520	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HLK66_RS11525	ENOG4105CXI	aluminum resistance protein
HLK66_RS11530	ENOG4105KV4	Transcriptional regulator
HLK66_RS11535	ENOG4105C5F	glutamine synthetase
HLK66_RS11570	ENOG4105KNA	-acetyltransferase
HLK66_RS11620	ENOG4108URH	decarboxylase
HLK66_RS11635	ENOG4105C7W	Xanthine dehydrogenase
HLK66_RS11645	ENOG4108XHQ	(2Fe-2S)-binding domain protein
HLK66_RS11660	ENOG4108UIN	ybak prolyl-trna synthetase associated region
HLK66_RS11665	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS11675	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HLK66_RS11685	ENOG4108SVB	resolvase
HLK66_RS11690	ENOG4105VPS	UPF0291 protein
HLK66_RS11695	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS11730	ENOG4105BZ1	(ABC) transporter
HLK66_RS11735	ENOG4105BZ1	(ABC) transporter
HLK66_RS11745	ENOG4107QIV	Cytochrome c biogenesis protein
HLK66_RS11750	ENOG4107YTP	response regulator receiver protein
HLK66_RS11785	ENOG4105VEQ	Cold shock protein
HLK66_RS11790	ENOG4107RFY	SbcCD D subunit
HLK66_RS11805	ENOG4105DER	m42 family
HLK66_RS11815	ENOG4105EEM	helicase
HLK66_RS11820	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HLK66_RS11845	ENOG4105KD7	acetyltransferase
HLK66_RS11850	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS11860	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS11880	ENOG4105PGS	Spore coat protein
HLK66_RS11885	ENOG4105E2A	Dehydrogenase
HLK66_RS11905	ENOG4107DZX	Small, acid-soluble spore protein P
HLK66_RS11915	ENOG4108I0Z	Aconitate hydratase
HLK66_RS11920	ENOG4105WCN	acetyltransferase
HLK66_RS11935	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS11945	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HLK66_RS11950	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLK66_RS11960	ENOG41075ZD	Small, acid-soluble spore protein N
HLK66_RS11965	ENOG4106F1P	AAA ATPase, central domain protein
HLK66_RS11980	ENOG4105MI2	
HLK66_RS11985	ENOG4105W8X	HesB YadR YfhF-family protein
HLK66_RS11990	ENOG4105PNM	synthesis protein
HLK66_RS11995	ENOG4105BZU	Histidine kinase
HLK66_RS12000	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HLK66_RS12025	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HLK66_RS12045	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS12050	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS12055	ENOG4108UJV	acyl-CoA thioesterase i
HLK66_RS12065	ENOG4108RS6	transposase
HLK66_RS12085	ENOG4105C28	cystathionine
HLK66_RS12090	ENOG4105C28	cystathionine
HLK66_RS12095	ENOG41069DP	small acid-soluble spore protein
HLK66_RS12100	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS12105	ENOG4105GR3	Histidine kinase
HLK66_RS12115	ENOG4105C7S	Dehydrogenase
HLK66_RS12135	ENOG4105WMR	Protein CrcB homolog
HLK66_RS12175	ENOG4105F1A	Pyruvate formate-lyase
HLK66_RS12190	ENOG4105DZ1	carboxypeptidase
HLK66_RS12195	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS12200	ENOG4105C5H	ABC transporter
HLK66_RS12205	ENOG4108QTI	)-transporter
HLK66_RS12230	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLK66_RS12235	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HLK66_RS12250	ENOG41069ER	domain protein
HLK66_RS12265	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
HLK66_RS12280	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HLK66_RS12285	ENOG4107YV9	domain protein
HLK66_RS12290	ENOG4105FFA	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity)
HLK66_RS12300	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
HLK66_RS12305	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HLK66_RS12325	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HLK66_RS12335	ENOG410667J	hydrolase
HLK66_RS12345	ENOG4105DPN	Oligoendopeptidase f
HLK66_RS12350	ENOG4105C5Q	Transcriptional regulator
HLK66_RS12355	ENOG4105CBC	glutamate synthase
HLK66_RS12360	ENOG4105BZ8	glutamate synthase
HLK66_RS12375	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HLK66_RS12380	ENOG4107ZE5	PPIases accelerate the folding of proteins
HLK66_RS12385	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HLK66_RS12390	ENOG4107TS3	membrane protein, TerC
HLK66_RS12395	ENOG4108XRC	Protein of unknown function (DUF458) 
HLK66_RS12410	ENOG4105C3F	Signal peptidase i
HLK66_RS12420	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS12435	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS12450	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HLK66_RS12455	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HLK66_RS12460	ENOG4108R6K	riboflavin synthase, subunit alpha
HLK66_RS12470	ENOG4105CGK	Exodeoxyribonuclease III
HLK66_RS12480	ENOG4105J7I	hydrolase
HLK66_RS12490	ENOG4105C1J	atp-dependent rna helicase
HLK66_RS12500	ENOG4105BZU	Histidine kinase
HLK66_RS12520	ENOG4105KVH	Transcriptional regulator
HLK66_RS12525	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
HLK66_RS12535	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HLK66_RS12545	ENOG4108B1Q	Ribonuclease
HLK66_RS12550	ENOG4108HRK	Histidine kinase
HLK66_RS12555	ENOG4108NEV	two component transcriptional regulator, LytTR family
HLK66_RS12565	ENOG4105BZU	Histidine kinase
HLK66_RS12570	ENOG4105BZU	Histidine kinase
HLK66_RS12575	ENOG4105CSV	Glutaminase
HLK66_RS12580	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HLK66_RS12590	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS12605	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLK66_RS12615	ENOG4105D5Q	Arginine ornithine antiporter
HLK66_RS12640	ENOG4105CD5	CoA-binding domain protein
HLK66_RS12645	ENOG4105CH6	catalase
HLK66_RS12650	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HLK66_RS12665	ENOG4105BZU	Histidine kinase
HLK66_RS12710	ENOG4108PJD	permease
HLK66_RS12725	ENOG4105C3M	thioredoxin reductase
HLK66_RS12730	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS12740	ENOG4105C5Y	PTS System
HLK66_RS12750	ENOG4105DUM	transcriptional regulator, lysR family
HLK66_RS12765	ENOG4105E98	transcriptional regulator DeoR family
HLK66_RS12800	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HLK66_RS12820	ENOG4105CVJ	phosphoglycerate mutase
HLK66_RS12860	ENOG4105K4P	CoA-binding domain protein
HLK66_RS12895	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
HLK66_RS12905	ENOG41082JN	Transcriptional regulator
HLK66_RS12920	ENOG4108ZRV	stage ii sporulation protein p
HLK66_RS12925	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HLK66_RS12930	ENOG4105F6E	Acyl-transferase
HLK66_RS12935	ENOG410667J	hydrolase
HLK66_RS12940	ENOG4105E98	transcriptional regulator DeoR family
HLK66_RS12955	ENOG4105DG6	mannose-6-phosphate isomerase
HLK66_RS12960	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLK66_RS12965	ENOG4105CZM	Major Facilitator
HLK66_RS12990	ENOG4105VKD	bioY protein
HLK66_RS12995	ENOG4108T5E	Copper resistance protein
HLK66_RS13015	ENOG4105DEN	Luciferase family
HLK66_RS13020	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HLK66_RS13030	ENOG4108X4Q	Hydrolase
HLK66_RS13040	ENOG4105SZ6	Thioredoxin
HLK66_RS13045	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HLK66_RS13060	ENOG4107AYK	membrAne
HLK66_RS13065	ENOG4105EW9	transcriptional regulator AsnC family
HLK66_RS13075	ENOG4105DR4	Methyltransferase
HLK66_RS13085	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HLK66_RS13115	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HLK66_RS13120	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HLK66_RS13135	ENOG4105BZ1	(ABC) transporter
HLK66_RS13170	ENOG4105DDQ	anthranilate synthase
HLK66_RS13175	ENOG4105CRQ	synthase (Component I)
HLK66_RS13180	ENOG4108RPX	mosc domain containing protein
HLK66_RS13190	ENOG4105DM4	PTS System
HLK66_RS13195	ENOG4105DE4	1-phosphofructokinase
HLK66_RS13200	ENOG4105E98	transcriptional regulator DeoR family
HLK66_RS13215	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HLK66_RS13240	ENOG4105DWF	phosphomethylpyrimidine kinase
HLK66_RS13255	ENOG4108PJD	permease
HLK66_RS13260	ENOG4105CKI	cobalamin synthesis protein
HLK66_RS13265	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS13275	ENOG4107S1Q	Phosphatase
HLK66_RS13300	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HLK66_RS13315	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLK66_RS13350	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HLK66_RS13355	ENOG4105WDJ	50S ribosomal protein L33
HLK66_RS13360	ENOG4105CKI	cobalamin synthesis protein
HLK66_RS13405	ENOG4106YAD	MORN repeat variant
HLK66_RS13470	ENOG4105NX3	Membrane
HLK66_RS13475	ENOG4105VMP	Transcriptional regulator
HLK66_RS13490	ENOG4105CZ9	Domain of unknown function (DU1801)
HLK66_RS13495	ENOG4108ZMX	Domain of unknown function (DU1801)
HLK66_RS13525	ENOG4105JVQ	RNA Polymerase
HLK66_RS13540	ENOG4105DDN	Pentapeptide repeat-containing protein
HLK66_RS13565	ENOG4105WG9	Conserved Protein
HLK66_RS13570	ENOG4106BRA	Membrane
HLK66_RS13590	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HLK66_RS13615	ENOG41086D8	Transcriptional regulator
HLK66_RS13620	ENOG4105BZG	amino acid carrier protein
HLK66_RS13650	ENOG4105E0Y	RtcB Protein
HLK66_RS13655	ENOG41090T1	Membrane
HLK66_RS13670	ENOG4107T5V	SNARE associated Golgi
HLK66_RS13675	ENOG41068VA	
HLK66_RS13690	ENOG4105D9U	N-acetyltransferase
HLK66_RS13700	ENOG4105CVJ	phosphoglycerate mutase
HLK66_RS13705	ENOG41068WN	
HLK66_RS13735	ENOG4105KWG	Pfam:DUF1696
HLK66_RS13755	ENOG4108ZJ4	polysaccharide deacetylase
HLK66_RS13780	ENOG4105CMU	LysR family (Transcriptional regulator
HLK66_RS13785	ENOG4105VAW	lrga family
HLK66_RS13790	ENOG41067MG	lrgb family
HLK66_RS13810	ENOG4105VEQ	Cold shock protein
HLK66_RS13815	ENOG4105C1J	atp-dependent rna helicase
HLK66_RS13820	ENOG4105VEQ	Cold shock protein
HLK66_RS13825	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HLK66_RS13830	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HLK66_RS13845	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
HLK66_RS13850	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HLK66_RS13855	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HLK66_RS13860	ENOG4105DQE	DNA ligase
HLK66_RS13870	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HLK66_RS13875	ENOG4105D58	Diguanylate phosphodiesterase
HLK66_RS13905	ENOG4107R5R	arsenical pump membrane protein
HLK66_RS13910	ENOG41082YX	Transcriptional regulator, arsr family
HLK66_RS13915	ENOG4107QMU	Mate efflux family protein
HLK66_RS13935	ENOG4105K4I	Scp-like extracellular
HLK66_RS13950	ENOG4105CKI	cobalamin synthesis protein
HLK66_RS13960	ENOG4108VXD	carboxy-peptidase
HLK66_RS13990	ENOG4105VSD	UPF0346 protein
HLK66_RS14000	ENOG4105E0X	reductase
HLK66_RS14005	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HLK66_RS14025	ENOG41090WU	lipolytic protein G-D-S-L family
HLK66_RS14030	ENOG4105BZU	Histidine kinase
HLK66_RS14035	ENOG4108RCR	degv family
HLK66_RS14040	ENOG4105C7B	Threonine dehydratase
HLK66_RS14045	ENOG4108UT2	hemolysin iii
HLK66_RS14050	ENOG4105F3R	pts system mannose fructose sorbose family iid
HLK66_RS14055	ENOG4105ETZ	PTS System
HLK66_RS14060	ENOG4108UZY	PTS System
HLK66_RS14080	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HLK66_RS14095	ENOG4106FN3	tellurium resistance protein
HLK66_RS14100	ENOG4108N0M	stress protein
HLK66_RS14110	ENOG4108TTB	tellurium resistance protein
HLK66_RS14125	ENOG4105DAX	Pfam:DUF2983
HLK66_RS14140	ENOG4107TS3	membrane protein, TerC
HLK66_RS14145	ENOG4106FN3	tellurium resistance protein
HLK66_RS14155	ENOG4107YX5	Pfam:DUF548
HLK66_RS14195	ENOG4108V06	Glutathione peroxidase
HLK66_RS14210	ENOG4105CVG	Homoserine O-transsuccinylase
HLK66_RS14225	ENOG4105KST	dependent repressor
HLK66_RS14230	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLK66_RS14235	ENOG4108QEG	Membrane
HLK66_RS14265	ENOG41081VK	Ribonuclease
HLK66_RS14295	ENOG4105DVE	abc transporter atp-binding protein
HLK66_RS14305	ENOG4105KHC	sulfurtransferase
HLK66_RS14310	ENOG410890F	Dynamin family
HLK66_RS14320	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS14325	ENOG4105CTD	carboxy-peptidase
HLK66_RS14330	ENOG4105DVT	helicase
HLK66_RS14340	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HLK66_RS14350	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
HLK66_RS14355	ENOG4106F55	Protein of unknown function (DUF1273)
HLK66_RS14365	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
HLK66_RS14375	ENOG4108MXF	Alpha Beta Hydrolase
HLK66_RS14380	ENOG4107Y70	Heat shock protein
HLK66_RS14420	ENOG4105BZ4	penicillin-binding protein
HLK66_RS14430	ENOG4105CSM	endonuclease III
HLK66_RS14440	ENOG4105C5S	asparaginyl-tRNA synthetase
HLK66_RS14445	ENOG4105CHM	Aminotransferase
HLK66_RS14455	ENOG4105DVT	helicase
HLK66_RS14460	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HLK66_RS14465	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HLK66_RS14480	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLK66_RS14485	ENOG4105CPK	Glycosyl transferase (Group 1
HLK66_RS14490	ENOG4105FJR	Lmbe family
HLK66_RS14500	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HLK66_RS14505	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
HLK66_RS14510	ENOG4108JYZ	YitT family
HLK66_RS14520	ENOG4105EU0	Major facilitator Superfamily
HLK66_RS14540	ENOG4108SXZ	UPF0302 protein
HLK66_RS14545	ENOG41068YB	TPR repeat-containing protein
HLK66_RS14555	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HLK66_RS14565	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HLK66_RS14570	ENOG4105KHN	chorismate mutase
HLK66_RS14575	ENOG4105D49	3-dehydroquinate synthase
HLK66_RS14585	ENOG4105BZU	Histidine kinase
HLK66_RS14590	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HLK66_RS14595	ENOG4105EAH	synthase
HLK66_RS14600	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HLK66_RS14605	ENOG4105XXQ	heptaprenyl diphosphate synthase component I
HLK66_RS14610	ENOG4105K70	DNA-binding protein
HLK66_RS14615	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
HLK66_RS14620	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HLK66_RS14625	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HLK66_RS14630	ENOG41065D1	
HLK66_RS14635	ENOG4105S2F	
HLK66_RS14645	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HLK66_RS14665	ENOG4105MSI	germination protein ypeb
HLK66_RS14670	ENOG4105F0V	Cell wall hydrolase
HLK66_RS14680	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
HLK66_RS14695	ENOG4107RGJ	metallophosphoesterase
HLK66_RS14710	ENOG4105WEF	catalase
HLK66_RS14725	ENOG4105I7S	Abortive infection protein
HLK66_RS14730	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HLK66_RS14745	ENOG4108SAX	Membrane
HLK66_RS14750	ENOG4105DR5	peptidase
HLK66_RS14770	ENOG4105BZU	Histidine kinase
HLK66_RS14775	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS14780	ENOG4105FE9	pseudouridine synthase
HLK66_RS14790	ENOG4108JIC	nucleoside recognition domain protein
HLK66_RS14795	ENOG4105DZ1	carboxypeptidase
HLK66_RS14800	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLK66_RS14805	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HLK66_RS14810	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HLK66_RS14825	ENOG4105PTM	secreted protein
HLK66_RS14845	ENOG4105G6R	Stage v sporulation protein ae
HLK66_RS14860	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK66_RS14865	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HLK66_RS14870	ENOG41082AN	stage II sporulation protein
HLK66_RS14875	ENOG4105DZ1	carboxypeptidase
HLK66_RS14880	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HLK66_RS14885	ENOG4105JVQ	RNA Polymerase
HLK66_RS14905	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HLK66_RS14940	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS14950	ENOG4105I3K	Ferric uptake regulator, Fur family
HLK66_RS14955	ENOG4105MZ9	stage II sporulation protein m
HLK66_RS14980	ENOG4105CPC	Aldo Keto reductase
HLK66_RS15000	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS15010	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HLK66_RS15015	ENOG4107TVP	HD domain protein
HLK66_RS15045	ENOG4105DJB	Major Facilitator Superfamily
HLK66_RS15050	ENOG4105CHR	reductase
HLK66_RS15055	ENOG4105CPQ	Dehydrogenase
HLK66_RS15060	ENOG4105CXK	mandelate racemase muconate lactonizing
HLK66_RS15130	ENOG4108RVA	ribokinase
HLK66_RS15135	ENOG41067QW	Transcriptional regulator
HLK66_RS15165	ENOG4108X3M	OsmC Ohr family protein
HLK66_RS15175	ENOG4107XZQ	multidrug resistance protein
HLK66_RS15180	ENOG4108A65	Transcriptional regulator
HLK66_RS15225	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HLK66_RS15245	ENOG4108IXY	short-chain dehydrogenase reductase
HLK66_RS15255	ENOG4105II7	pyrroline-5-carboxylate reductase
HLK66_RS15260	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HLK66_RS15265	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HLK66_RS15270	ENOG4107RN3	metallophosphoesterase
HLK66_RS15280	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HLK66_RS15285	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HLK66_RS15295	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HLK66_RS15305	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
HLK66_RS15310	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS15315	ENOG4105E5Q	amino acid AbC transporter
HLK66_RS15320	ENOG4108HW3	(ABC) transporter
HLK66_RS15325	ENOG4108Y6J	UPF0403 protein
HLK66_RS15330	ENOG4105C7S	Dehydrogenase
HLK66_RS15335	ENOG4105CPP	Dehydrogenase, E1 component
HLK66_RS15350	ENOG4105CKM	Branched-chain carboxylic acid kinase
HLK66_RS15355	ENOG4108JUB	Transcriptional regulator
HLK66_RS15360	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HLK66_RS15375	ENOG4107QQR	Sporulation
HLK66_RS15380	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HLK66_RS15385	ENOG4105S1Z	Stage IV sporulation protein B
HLK66_RS15390	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HLK66_RS15395	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
HLK66_RS15400	ENOG4105DX0	Hemolysin A
HLK66_RS15405	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HLK66_RS15410	ENOG4105CTB	Polyprenyl synthetase
HLK66_RS15415	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HLK66_RS15425	ENOG4105M7K	Involved in the transcription termination process (By similarity)
HLK66_RS15430	ENOG4108ZSR	alkaline shock protein
HLK66_RS15435	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HLK66_RS15455	ENOG410644B	Stage III sporulation protein af
HLK66_RS15465	ENOG4105KQ4	Stage iii sporulation protein ad
HLK66_RS15470	ENOG4108CQH	stage III sporulation protein AC
HLK66_RS15475	ENOG4105KR5	Stage iii sporulation protein
HLK66_RS15480	ENOG4105CD2	stage iii sporulation protein aa
HLK66_RS15490	ENOG4105G6Z	alkaline phosphatase
HLK66_RS15500	ENOG4105CS2	ec 3.2.1.21
HLK66_RS15505	ENOG4105CJQ	hydrolase, family 31
HLK66_RS15510	ENOG41066F8	ROK family
HLK66_RS15520	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS15540	ENOG4105EQD	regulatoR
HLK66_RS15545	ENOG4105C2F	Histidine kinase
HLK66_RS15565	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HLK66_RS15570	ENOG4105DC7	peptidase M24
HLK66_RS15580	ENOG4105CBJ	Metal-dependent enzyme
HLK66_RS15625	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HLK66_RS15630	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
HLK66_RS15635	ENOG4105WZW	rhodanese family
HLK66_RS15640	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLK66_RS15645	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLK66_RS15650	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HLK66_RS15655	ENOG4105C0D	helicase
HLK66_RS15690	ENOG4106855	Competence protein
HLK66_RS15750	ENOG41060YP	
HLK66_RS15770	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HLK66_RS15875	ENOG4105CAR	Terminase, large subunit
HLK66_RS15955	ENOG4105QBX	endodeoxyribonuclease RusA
HLK66_RS16045	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HLK66_RS16050	ENOG4108C33	Resolvase
HLK66_RS16105	ENOG41060YP	
HLK66_RS16125	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HLK66_RS16310	ENOG4105QBX	endodeoxyribonuclease RusA
HLK66_RS16405	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HLK66_RS16410	ENOG4108C33	Resolvase
HLK66_RS16425	ENOG4105PGM	cation diffusion facilitator family transporter
HLK66_RS16430	ENOG4105H3G	oxidoreductase
HLK66_RS16445	ENOG4105C5X	domain protein
HLK66_RS16470	ENOG4105DKQ	ROK family
HLK66_RS16510	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HLK66_RS16515	ENOG4105WDJ	50S ribosomal protein L33
HLK66_RS16545	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HLK66_RS16550	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS16555	ENOG4105E2Z	phosphate ABC transporter (Permease
HLK66_RS16560	ENOG4105C8U	phosphate abc transporter
HLK66_RS16565	ENOG4105CVA	phosphate
HLK66_RS16570	ENOG4107RF6	penicillin-binding protein
HLK66_RS16575	ENOG4107RF6	penicillin-binding protein
HLK66_RS16590	ENOG4107V6Q	Cyclic nucleotide-binding domain
HLK66_RS16595	ENOG4105SXS	Protein of unknown function (DUF456)
HLK66_RS16605	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS16615	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HLK66_RS16625	ENOG4108U5J	'-nucleotidase
HLK66_RS16630	ENOG4105N80	Ferric uptake regulator, Fur family
HLK66_RS16640	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HLK66_RS16655	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HLK66_RS16660	ENOG4105EGD	dinuclear metal center protein, YbgI family
HLK66_RS16675	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK66_RS16685	ENOG4108UPT	UPF0178 protein
HLK66_RS16690	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HLK66_RS16700	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HLK66_RS16705	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HLK66_RS16710	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
HLK66_RS16720	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HLK66_RS16725	ENOG4105KG3	cytidine deaminase
HLK66_RS16730	ENOG4107YR5	Diacylglycerol kinase
HLK66_RS16735	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HLK66_RS16740	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HLK66_RS16745	ENOG4105C9A	Phoh family
HLK66_RS16755	ENOG41068P3	sporulation protein YqfC
HLK66_RS16765	ENOG4105DI5	UPF0365 protein
HLK66_RS16770	ENOG4105F7J	membrane-bound serine protease
HLK66_RS16775	ENOG4105KTH	gatB Yqey
HLK66_RS16800	ENOG4105BZ1	(ABC) transporter
HLK66_RS16805	ENOG4105BZ1	(ABC) transporter
HLK66_RS16810	ENOG4106HBX	Transcriptional Regulator AraC Family
HLK66_RS16815	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HLK66_RS16820	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HLK66_RS16825	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HLK66_RS16830	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HLK66_RS16835	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HLK66_RS16840	ENOG4105CFG	Acts as a chaperone (By similarity)
HLK66_RS16845	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLK66_RS16850	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HLK66_RS16855	ENOG4105CSA	Coproporphyrinogen iii oxidase
HLK66_RS16860	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HLK66_RS16875	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HLK66_RS16880	ENOG4105TQK	DNA polymerase iii, delta' subunit
HLK66_RS16885	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HLK66_RS16890	ENOG4108UK2	deaminase
HLK66_RS16895	ENOG4105KQC	Competence protein
HLK66_RS16905	ENOG4105DXX	methyltransferase
HLK66_RS16910	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HLK66_RS16915	ENOG4108WF2	Metal Dependent Phosphohydrolase
HLK66_RS16920	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HLK66_RS16925	ENOG410812S	Rna-binding protein
HLK66_RS16935	ENOG4105CQW	ribosome biogenesis GTPase YqeH
HLK66_RS16940	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
HLK66_RS16950	ENOG4105DJ4	phosphatidylserine decarboxylase
HLK66_RS16955	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HLK66_RS16970	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLK66_RS16990	ENOG4107Y5K	Resolvase
HLK66_RS17020	ENOG41060YP	
HLK66_RS17035	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HLK66_RS17050	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HLK66_RS17060	ENOG4107TXC	Transcriptional regulator
HLK66_RS17090	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HLK66_RS17095	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HLK66_RS17105	ENOG4105DQ6	Transposase
HLK66_RS17120	ENOG4105C28	cystathionine
HLK66_RS17130	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HLK66_RS17135	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
HLK66_RS17160	ENOG4107XRG	penicillin-binding protein
HLK66_RS17165	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HLK66_RS17170	ENOG4105DBI	uridine monophosphokinase
HLK66_RS17175	ENOG4105CFP	Peptidase U32
HLK66_RS17180	ENOG4105XYU	peptidase (U32 family)
HLK66_RS17190	ENOG4105HHA	aminodeoxychorismate lyase
HLK66_RS17195	ENOG4105VPH	UPF0473 protein
HLK66_RS17205	ENOG4105VBH	UPF0297 protein
HLK66_RS17210	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HLK66_RS17215	ENOG4105C02	permease
HLK66_RS17225	ENOG41060CR	
HLK66_RS17230	ENOG4105C7H	Helicase, RecD TraA family
HLK66_RS17240	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HLK66_RS17245	ENOG4105C3J	Cysteine desulfurase
HLK66_RS17270	ENOG4105DTQ	mandelate racemase muconate lactonizing
HLK66_RS17285	ENOG4105EG2	ABC transporter, permease
HLK66_RS17300	ENOG4105D1H	recombination factor protein RarA
HLK66_RS17305	ENOG4108TU7	Inherit from COG: (ABC) transporter
HLK66_RS17310	ENOG4105CJ1	ABC, transporter
HLK66_RS17315	ENOG4105CZV	ABC transporter
HLK66_RS17320	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS17330	ENOG4105CUZ	uba thif-type nad fad binding protein
HLK66_RS17335	ENOG4105C9M	aspartyl-trna synthetase
HLK66_RS17340	ENOG4105CUT	histidyl-tRNA synthetase
HLK66_RS17350	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HLK66_RS17360	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HLK66_RS17365	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HLK66_RS17370	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HLK66_RS17375	ENOG41067VP	Protein of unknown function (DUF1049)
HLK66_RS17380	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HLK66_RS17390	ENOG4105CKP	Polysaccharide Biosynthesis Protein
HLK66_RS17395	ENOG4108QG2	Membrane
HLK66_RS17400	ENOG4105NAP	
HLK66_RS17405	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS17410	ENOG4105VIE	preprotein translocase, subunit YajC
HLK66_RS17420	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HLK66_RS17425	ENOG41061AI	Protein of unknown function (DUF2905)
HLK66_RS17435	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HLK66_RS17470	ENOG4105CQC	Prephenate dehydratase
HLK66_RS17475	ENOG41090I5	UPF0735 ACT domain-containing protein
HLK66_RS17480	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLK66_RS17490	ENOG4105K46	50S ribosomal protein l27
HLK66_RS17495	ENOG4105X36	(ribosomal) protein
HLK66_RS17500	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HLK66_RS17505	ENOG4105C03	ribonuclease
HLK66_RS17520	ENOG4107QMS	site-determining protein
HLK66_RS17525	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HLK66_RS17530	ENOG4105YHC	Rod shape-determining protein MreD
HLK66_RS17535	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HLK66_RS17540	ENOG4105DFF	Rod shape-determining protein mreb
HLK66_RS17545	ENOG4105W5Q	DNA repair protein (RadC
HLK66_RS17550	ENOG4108Z03	MAF-like protein
HLK66_RS17580	ENOG4106A3R	peptidase
HLK66_RS17595	ENOG4105CZX	twitching motility protein
HLK66_RS17600	ENOG4107QHF	type ii secretion system protein e
HLK66_RS17640	ENOG4105BZU	Histidine kinase
HLK66_RS17650	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HLK66_RS17655	ENOG4106AR7	Spore coat protein
HLK66_RS17660	ENOG41068KH	stage VI sporulation protein D
HLK66_RS17660	ENOG41068KH	stage VI sporulation protein D
HLK66_RS17665	ENOG4107BJW	polysaccharide deacetylase
HLK66_RS17675	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS17685	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HLK66_RS17690	ENOG4105D52	delta-aminolevulinic acid dehydratase
HLK66_RS17700	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HLK66_RS17710	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HLK66_RS17720	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HLK66_RS17725	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HLK66_RS17730	ENOG4108IUQ	atp-dependent protease
HLK66_RS17735	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HLK66_RS17740	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HLK66_RS17750	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HLK66_RS17755	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HLK66_RS17760	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HLK66_RS17765	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HLK66_RS17770	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HLK66_RS17775	ENOG4108ZP8	Acetolactate synthase small subunit
HLK66_RS17780	ENOG4105C7K	acetolactate synthase
HLK66_RS17790	ENOG4107KM7	Heat induced stress protein YflT
HLK66_RS17805	ENOG4105M59	Phosphodiesterase, mj0936 family
HLK66_RS17810	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HLK66_RS17820	ENOG4108XJQ	germination protein
HLK66_RS17825	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HLK66_RS17830	ENOG41067TZ	transcriptional regulator, MarR family
HLK66_RS17835	ENOG4105PFC	Transcriptional regulator
HLK66_RS17845	ENOG4105E33	succinate dehydrogenase
HLK66_RS17855	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
HLK66_RS17875	ENOG4105K63	Thioredoxin
HLK66_RS17880	ENOG4105C10	Electron transfer flavoprotein
HLK66_RS17885	ENOG4105BZJ	Electron transfer flavoprotein
HLK66_RS17890	ENOG4105CEY	Amp-dependent synthetase and ligase
HLK66_RS17905	ENOG4105DCG	PHP domain protein
HLK66_RS17915	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HLK66_RS17920	ENOG41066F8	ROK family
HLK66_RS17925	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS17930	ENOG4105DRS	transport system, permease
HLK66_RS17945	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HLK66_RS17950	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HLK66_RS17955	ENOG4108RWN	rrna methyltransferase
HLK66_RS17960	ENOG41067MF	small acid-soluble spore protein
HLK66_RS17965	ENOG4105CMG	Carbohydrate kinase
HLK66_RS17970	ENOG4105C93	Xylose Isomerase
HLK66_RS17975	ENOG4105E2R	ROK family
HLK66_RS17980	ENOG4105C02	permease
HLK66_RS17985	ENOG4105CN9	Peptidase m42 family protein
HLK66_RS18000	ENOG410696E	Membrane
HLK66_RS18005	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HLK66_RS18015	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HLK66_RS18020	ENOG4105C22	threonyL-tRNA synthetase
HLK66_RS18025	ENOG4108TDW	sporulation protein YtxC
HLK66_RS18050	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HLK66_RS18065	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HLK66_RS18070	ENOG4105C2M	dna polymerase I
HLK66_RS18075	ENOG4105BZU	Histidine kinase
HLK66_RS18080	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK66_RS18085	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HLK66_RS18090	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HLK66_RS18095	ENOG4105BZN	citrate synthase
HLK66_RS18100	ENOG4108VMM	UPF0756 membrane protein
HLK66_RS18105	ENOG4108REF	Sporulation integral membrane protein ytvi
HLK66_RS18155	ENOG4105DMW	Dehydrogenase reductase
HLK66_RS18170	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS18180	ENOG4107QNR	UPF0135 protein
HLK66_RS18185	ENOG4105MU9	integral membrane protein
HLK66_RS18195	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HLK66_RS18200	ENOG4105XN3	extracellular solute-binding protein family 1
HLK66_RS18205	ENOG41075H3	AraC family transcriptional regulator
HLK66_RS18210	ENOG4105C2F	Histidine kinase
HLK66_RS18215	ENOG4105FS0	cytoplasmic membrane protein
HLK66_RS18220	ENOG4105CA9	Pyruvate kinase
HLK66_RS18230	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HLK66_RS18240	ENOG4107YCY	Transcriptional regulator
HLK66_RS18245	ENOG4105C0B	DNA polymerase III (alpha subunit)
HLK66_RS18250	ENOG4105VV2	
HLK66_RS18260	ENOG4105SFS	phosphoesterase RecJ domain protein
HLK66_RS18275	ENOG4105DC7	peptidase M24
HLK66_RS18290	ENOG4107YZX	Universal stress protein
HLK66_RS18295	ENOG4105CH7	arginosuccinase
HLK66_RS18300	ENOG4105CDH	Citrulline--aspartate ligase
HLK66_RS18305	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
HLK66_RS18310	ENOG4105EEM	helicase
HLK66_RS18320	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HLK66_RS18330	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HLK66_RS18335	ENOG4105KBJ	sporulation protein ytfj
HLK66_RS18345	ENOG4105VK3	rdd domain containing protein
HLK66_RS18350	ENOG4105D07	Signal peptide peptidase, SppA
HLK66_RS18355	ENOG4105FR1	rard protein
HLK66_RS18360	ENOG4105EFZ	amidohydrolase
HLK66_RS18365	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HLK66_RS18375	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HLK66_RS18385	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
HLK66_RS18390	ENOG4108W76	histidinol phosphate phosphatase hisj family
HLK66_RS18395	ENOG4105U5Y	Transcriptional regulator
HLK66_RS18405	ENOG4105BZU	Histidine kinase
HLK66_RS18410	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HLK66_RS18430	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS18435	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HLK66_RS18440	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HLK66_RS18460	ENOG4105C88	aminopeptidase
HLK66_RS18465	ENOG4105DFU	Cell wall formation (By similarity)
HLK66_RS18475	ENOG4108NKM	UPF0354 protein
HLK66_RS18510	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HLK66_RS18520	ENOG4108V15	phosphotransferase enzyme family
HLK66_RS18525	ENOG4108IUM	Glycogen debranching enzyme
HLK66_RS18535	ENOG4107F58	2'-5' rna ligase
HLK66_RS18545	ENOG4107QSE	Dipeptidase
HLK66_RS18550	ENOG4105E09	nadh pyrophosphatase
HLK66_RS18555	ENOG4105YW5	deoR family transcriptional regulator
HLK66_RS18570	ENOG4105CBX	hi0933 family
HLK66_RS18580	ENOG41085GJ	domain protein
HLK66_RS18585	ENOG4105C8T	Leucyl-tRNA synthetase
HLK66_RS18595	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HLK66_RS18600	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HLK66_RS18605	ENOG4107TB6	phosphoglycerate mutase
HLK66_RS18610	ENOG410605W	Major Facilitator
HLK66_RS18625	ENOG4105N5T	Radical SAM Protein
HLK66_RS18640	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HLK66_RS18650	ENOG4105CAQ	asparagine synthetase
HLK66_RS18655	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HLK66_RS18685	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HLK66_RS18695	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HLK66_RS18700	ENOG4108V2W	Carbonate dehydratase
HLK66_RS18720	ENOG4108IPT	Naphthoate synthase
HLK66_RS18725	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HLK66_RS18735	ENOG4105E4F	Isochorismate synthase
HLK66_RS18750	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HLK66_RS18890	ENOG4105KT7	mgtC SapB transporter
HLK66_RS18910	ENOG4105BZU	Histidine kinase
HLK66_RS18920	ENOG41067CD	Small, acid-soluble spore protein Tlp
HLK66_RS18925	ENOG4105CIS	alcohol dehydrogenase
HLK66_RS18930	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HLK66_RS18935	ENOG4108DBC	nitroreductase
HLK66_RS18945	ENOG4105QVS	general stress protein
HLK66_RS18950	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLK66_RS18965	ENOG4105CAH	Chromate
HLK66_RS18970	ENOG4105FGV	Chromate
HLK66_RS18980	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HLK66_RS18985	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HLK66_RS18990	ENOG41067SE	Tetr family transcriptional regulator
HLK66_RS18995	ENOG4107PBV	potassium channel
HLK66_RS19010	ENOG4107QW4	alcohol dehydrogenase
HLK66_RS19015	ENOG4105WG9	Conserved Protein
HLK66_RS19020	ENOG4105C8Y	Acetylornithine aminotransferase
HLK66_RS19030	ENOG4105CHM	Aminotransferase
HLK66_RS19035	ENOG4108ZB6	transcriptional regulator AsnC family
HLK66_RS19045	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS19050	ENOG4108UMI	ABC transporter, permease
HLK66_RS19055	ENOG4105D01	(LipO)protein
HLK66_RS19065	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HLK66_RS19070	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HLK66_RS19090	ENOG4105D65	subunit l
HLK66_RS19095	ENOG4105HC0	Na H antiporter
HLK66_RS19100	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HLK66_RS19105	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HLK66_RS19110	ENOG4105SC1	monovalent cation H antiporter subunit E
HLK66_RS19120	ENOG4105KJM	monovalent cation h antiporter subunit g
HLK66_RS19140	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HLK66_RS19170	ENOG4105CHR	reductase
HLK66_RS19185	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HLK66_RS19195	ENOG41069ER	domain protein
HLK66_RS19200	ENOG4105CAY	ferredoxin--nadp reductase
HLK66_RS19205	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HLK66_RS19215	ENOG4105ZKE	UPF0349 protein
HLK66_RS19230	ENOG41083MR	nifu domain-containing protein
HLK66_RS19235	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HLK66_RS19240	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
HLK66_RS19245	ENOG4105D6E	homoserine dehydrogenase
HLK66_RS19255	ENOG4108W5N	phosphatidylglycerophosphatase a
HLK66_RS19260	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HLK66_RS19270	ENOG4105BZU	Histidine kinase
HLK66_RS19280	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HLK66_RS19285	ENOG4105FAA	peptidase M23
HLK66_RS19290	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLK66_RS19295	ENOG4105KZD	Domain of unknown function (DUF1805)
HLK66_RS19300	ENOG4107R8B	5'-nucleotidase
HLK66_RS19305	ENOG4105I3N	Conserved Protein
HLK66_RS19315	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
HLK66_RS19330	ENOG4105J4Q	Transcriptional regulator
HLK66_RS19335	ENOG4108HCJ	Hydrolase
HLK66_RS19340	ENOG4108UW5	maltose o-acetyltransferase
HLK66_RS19345	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
HLK66_RS19355	ENOG4105DKQ	ROK family
HLK66_RS19360	ENOG4105DIW	FeS assembly protein SUFB
HLK66_RS19365	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HLK66_RS19370	ENOG4105C9B	Cysteine desulfurase
HLK66_RS19375	ENOG4105JRK	feS assembly protein SufD
HLK66_RS19380	ENOG4105C3K	feS assembly ATPase SufC
HLK66_RS19385	ENOG4105D01	(LipO)protein
HLK66_RS19390	ENOG4108UMI	ABC transporter, permease
HLK66_RS19395	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS19415	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HLK66_RS19420	ENOG41080E8	Transcriptional regulator, Spx MgsR family
HLK66_RS19425	ENOG4105C1G	acyl-Coa dehydrogenase
HLK66_RS19460	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS19470	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS19475	ENOG4105DRP	amino acid AbC transporter
HLK66_RS19490	ENOG4105D7K	pfkb domain protein
HLK66_RS19495	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HLK66_RS19500	ENOG4106F5Q	Membrane
HLK66_RS19505	ENOG4105EYF	MMPL domain protein
HLK66_RS19510	ENOG41067TZ	transcriptional regulator, MarR family
HLK66_RS19515	ENOG4105KA0	thioesterase Superfamily protein
HLK66_RS19535	ENOG4105FKQ	transcriptional regulator
HLK66_RS19540	ENOG4105KVH	Transcriptional regulator
HLK66_RS19545	ENOG4108VA3	3-hexulose-6-phosphate synthase
HLK66_RS19550	ENOG41080HJ	6-phospho 3-hexuloisomerase
HLK66_RS19575	ENOG4105C5H	ABC transporter
HLK66_RS19585	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS19590	ENOG4105DDC	Oxidoreductase domain protein
HLK66_RS19600	ENOG4105F5H	Glycosyl Hydrolase Family 88
HLK66_RS19605	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HLK66_RS19610	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK66_RS19615	ENOG410769Z	extracellular solute-binding protein family 1
HLK66_RS19620	ENOG4105EQD	regulatoR
HLK66_RS19625	ENOG4105C2F	Histidine kinase
HLK66_RS19645	ENOG4107MMM	Anti-sigma-factor antagonist
HLK66_RS19660	ENOG4105C26	Dehydrogenase
HLK66_RS19665	ENOG4105FF2	Type I DHQase
HLK66_RS19690	ENOG4105DRS	transport system, permease
HLK66_RS19695	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK66_RS19700	ENOG4107YY3	extracellular solute-binding protein family 1
HLK66_RS19710	ENOG41075H3	AraC family transcriptional regulator
HLK66_RS19720	ENOG4105C59	p-type ATPase
HLK66_RS19725	ENOG410681U	heavy metal transport detoxification protein
HLK66_RS19735	ENOG4105DRR	Transcriptional regulator, GntR family
HLK66_RS19750	ENOG4107TXC	Transcriptional regulator
HLK66_RS19755	ENOG4108TZY	GntR Family Transcriptional Regulator
HLK66_RS19760	ENOG4107ZXU	DSBA oxidoreductase
HLK66_RS19800	ENOG4105EAB	amino acid AbC transporter
HLK66_RS19805	ENOG4105DRP	amino acid AbC transporter
HLK66_RS19810	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS19825	ENOG4105DRS	transport system, permease
HLK66_RS19835	ENOG4108JE9	extracellular solute-binding protein family 1
HLK66_RS19845	ENOG4105C26	Dehydrogenase
HLK66_RS19855	ENOG4105CPQ	Dehydrogenase
HLK66_RS19860	ENOG4105DT3	PTS system, galactitol-specific IIc component
HLK66_RS19870	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HLK66_RS19875	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS19885	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HLK66_RS19900	ENOG4105XZU	Preprotein translocase, subunit SecG
HLK66_RS19910	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HLK66_RS19945	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HLK66_RS19950	ENOG4105KRI	phosphocarrier protein (HPr
HLK66_RS19960	ENOG4105CHW	UPF0052 protein
HLK66_RS19965	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HLK66_RS19970	ENOG4108Z4K	mutator MutT protein
HLK66_RS19985	ENOG4105C3M	thioredoxin reductase
HLK66_RS20000	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HLK66_RS20005	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HLK66_RS20010	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HLK66_RS20015	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HLK66_RS20020	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HLK66_RS20025	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HLK66_RS20030	ENOG4107RN8	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HLK66_RS20035	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HLK66_RS20040	ENOG4108S4C	acetyltransferase
HLK66_RS20045	ENOG4107XGZ	Hydrolase
HLK66_RS20055	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HLK66_RS20060	ENOG41086DT	Membrane protein of unknown function
HLK66_RS20065	ENOG4108PY7	
HLK66_RS20070	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HLK66_RS20075	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HLK66_RS20100	ENOG4105C0A	alcohol dehydrogenase
HLK66_RS20110	ENOG4105EYF	MMPL domain protein
HLK66_RS20115	ENOG4105JVQ	RNA Polymerase
HLK66_RS20120	ENOG4108P49	AntiSigma factor
HLK66_RS20140	ENOG4105C5R	Aminotransferase
HLK66_RS20145	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HLK66_RS20150	ENOG4105G9B	Transcriptional regulator
HLK66_RS20160	ENOG4105C6K	Malic enzyme
HLK66_RS20175	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
HLK66_RS20185	ENOG4107EFR	Flavocytochrome c
HLK66_RS20190	ENOG4108ZMQ	domain protein
HLK66_RS20195	ENOG4108JJ8	(ABC) transporter
HLK66_RS20200	ENOG4108JJ9	ABC, transporter
HLK66_RS20220	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HLK66_RS20225	ENOG4105CTQ	phosphohexokinase
HLK66_RS20230	ENOG4108YZG	isomerase
HLK66_RS20240	ENOG4105CPQ	Dehydrogenase
HLK66_RS20245	ENOG4105DT3	PTS system, galactitol-specific IIc component
HLK66_RS20250	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
HLK66_RS20255	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
HLK66_RS20270	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HLK66_RS20275	ENOG4105CTQ	phosphohexokinase
HLK66_RS20280	ENOG4108YZG	isomerase
HLK66_RS20285	ENOG4105CV8	reductase
HLK66_RS20290	ENOG4105F27	Major Facilitator
HLK66_RS20295	ENOG4105KVH	Transcriptional regulator
HLK66_RS20300	ENOG4105CN1	protease
HLK66_RS20310	ENOG4105C59	p-type ATPase
HLK66_RS20315	ENOG4105C59	p-type ATPase
HLK66_RS20325	ENOG4105DR5	peptidase
HLK66_RS20330	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HLK66_RS20335	ENOG4105CAK	Cell division ATP-binding protein ftsE
HLK66_RS20370	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HLK66_RS20390	ENOG4108I5D	sulfate abc transporter
HLK66_RS20395	ENOG4105F38	ABC transporter, permease
HLK66_RS20400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS20415	ENOG4107XBN	GntR Family Transcriptional Regulator
HLK66_RS20420	ENOG4105FGV	Chromate
HLK66_RS20425	ENOG4105CAH	Chromate
HLK66_RS20430	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HLK66_RS20455	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HLK66_RS20470	ENOG4105MQ3	flagellar protein FliS
HLK66_RS20475	ENOG4107RT6	flagellar hook-associated
HLK66_RS20480	ENOG41083S7	flagellar protein FlaG
HLK66_RS20500	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS20515	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS20525	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HLK66_RS20550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS20565	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS20585	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HLK66_RS20590	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
HLK66_RS20595	ENOG4105MKD	
HLK66_RS20600	ENOG4105DTJ	flagellar hook-associated protein
HLK66_RS20605	ENOG4105E1Q	flagellar hook-associated protein
HLK66_RS20645	ENOG4105WH1	Two component transcriptional regulator luxr family
HLK66_RS20650	ENOG4105BZU	Histidine kinase
HLK66_RS20655	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HLK66_RS20660	ENOG4108KGH	TRANSCRIPTIONal
HLK66_RS20665	ENOG4105JFG	SpoIID LytB domain protein
HLK66_RS20685	ENOG4105ESV	Glycosyl transferase, family 4
HLK66_RS20695	ENOG4105EY8	ABC transporter
HLK66_RS20710	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HLK66_RS20720	ENOG4107SJB	teichoic acid biosynthesis
HLK66_RS20725	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
HLK66_RS20735	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HLK66_RS20740	ENOG4105CMR	udp-glucose 4-epimerase
HLK66_RS20745	ENOG4107T9C	Alpha amylase catalytic region
HLK66_RS20750	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
HLK66_RS20765	ENOG4105Z8H	single-stranded DNA-binding protein
HLK66_RS20775	ENOG4105Q95	Cupin 2, conserved barrel domain protein
HLK66_RS20780	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS20785	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS20790	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HLK66_RS20815	ENOG4105C26	Dehydrogenase
HLK66_RS20835	ENOG4105I1F	Resistance protein
HLK66_RS20840	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
HLK66_RS20845	ENOG4106KE4	Dehydrogenase
HLK66_RS20850	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HLK66_RS20855	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HLK66_RS20860	ENOG4105FTQ	Dna gyrase
HLK66_RS20880	ENOG4105D9N	nucleoside
HLK66_RS20890	ENOG4105D01	(LipO)protein
HLK66_RS20895	ENOG4108UMI	ABC transporter, permease
HLK66_RS20900	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS20910	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
HLK66_RS20915	ENOG4105FKZ	Methyl-accepting chemotaxis
HLK66_RS20920	ENOG4105CJZ	response regulator
HLK66_RS20925	ENOG4105EWM	Histidine kinase
HLK66_RS20930	ENOG4105C19	ABC transporter
HLK66_RS20950	ENOG4105C87	Aminotransferase class I and II
HLK66_RS20955	ENOG4105BZU	Histidine kinase
HLK66_RS20990	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HLK66_RS21000	ENOG4108TVJ	Nitroreductase
HLK66_RS21015	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HLK66_RS21025	ENOG4108K4B	hydrolase
HLK66_RS21055	ENOG4105DPN	Oligoendopeptidase f
HLK66_RS21060	ENOG4105CS2	ec 3.2.1.21
HLK66_RS21065	ENOG4108S3Y	transcriptional regulator
HLK66_RS21075	ENOG4105EC8	Methyl-accepting chemotaxis
HLK66_RS21090	ENOG4105K7K	Transcriptional regulator
HLK66_RS21100	ENOG4105D2N	Aldolase
HLK66_RS21105	ENOG4105DM4	PTS System
HLK66_RS21110	ENOG4108YRF	PTS System
HLK66_RS21125	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HLK66_RS21145	ENOG4107E6A	Cytochrome p-450
HLK66_RS21150	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HLK66_RS21155	ENOG4105EQ0	Major Facilitator superfamily
HLK66_RS21160	ENOG4105C8I	hydrolase, family 38
HLK66_RS21180	ENOG4105EQD	regulatoR
HLK66_RS21185	ENOG4105C2F	Histidine kinase
HLK66_RS21200	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS21210	ENOG4105CF7	AraC family transcriptional regulator
HLK66_RS21215	ENOG4105CHR	reductase
HLK66_RS21220	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS21225	ENOG4105J7D	transcriptional regulator
HLK66_RS21230	ENOG4108RCM	Nitroreductase
HLK66_RS21235	ENOG4105EQD	regulatoR
HLK66_RS21240	ENOG4105C2F	Histidine kinase
HLK66_RS21255	ENOG4105EK5	Glycoside hydrolase family 8
HLK66_RS21260	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS21275	ENOG4105FDP	GntR family transcriptional regulator
HLK66_RS21280	ENOG4105CXK	mandelate racemase muconate lactonizing
HLK66_RS21285	ENOG4105C5Y	PTS System
HLK66_RS21300	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS21305	ENOG4105C4Y	ABC transporter
HLK66_RS21310	ENOG4107VQW	regulatoR
HLK66_RS21320	ENOG4105C5Y	PTS System
HLK66_RS21330	ENOG4106XGU	
HLK66_RS21340	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HLK66_RS21345	ENOG4105BZW	Glycerate kinase
HLK66_RS21350	ENOG4107QQ0	gntp family
HLK66_RS21370	ENOG4105F38	ABC transporter, permease
HLK66_RS21375	ENOG4105F38	ABC transporter, permease
HLK66_RS21380	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS21385	ENOG4105CPN	adenine deaminase
HLK66_RS21400	ENOG4105FTV	AraC Family Transcriptional Regulator
HLK66_RS21410	ENOG4105EMU	Dehydrogenase
HLK66_RS21435	ENOG41067AE	Membrane-bound metal-dependent hydrolase
HLK66_RS21440	ENOG4105CS2	ec 3.2.1.21
HLK66_RS21445	ENOG4105CS2	ec 3.2.1.21
HLK66_RS21450	ENOG4105C5Y	PTS System
HLK66_RS21465	ENOG4105DQ5	transport system permease protein
HLK66_RS21470	ENOG4105EHG	Permease protein
HLK66_RS21475	ENOG4105WH1	Two component transcriptional regulator luxr family
HLK66_RS21480	ENOG4108KMM	Diguanylate cyclase
HLK66_RS21485	ENOG4105DY9	regulatoR
HLK66_RS21495	ENOG4108W8B	Beta-lactamase domain protein
HLK66_RS21520	ENOG4105D2N	Aldolase
HLK66_RS21540	ENOG4106ETB	IIa component
HLK66_RS21545	ENOG4105DEN	Luciferase family
HLK66_RS21560	ENOG4108KGH	TRANSCRIPTIONal
HLK66_RS21565	ENOG4105K4I	Scp-like extracellular
HLK66_RS21595	ENOG4107YB6	acetyltransferase, (GNAT) family
HLK66_RS21610	ENOG4105VCP	PTS System
HLK66_RS21620	ENOG4105CK1	PTS System
HLK66_RS21625	ENOG4105CS2	ec 3.2.1.21
HLK66_RS21630	ENOG4108TZY	GntR Family Transcriptional Regulator
HLK66_RS21655	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HLK66_RS21665	ENOG4105DRS	transport system, permease
HLK66_RS21670	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK66_RS21680	ENOG4105E2R	ROK family
HLK66_RS21685	ENOG41088CQ	domain protein
HLK66_RS21705	ENOG41073R8	VanW family
HLK66_RS21725	ENOG4105CMD	Transcriptional regulator, GntR family
HLK66_RS21740	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
HLK66_RS21780	ENOG4108PGP	mmge prpd family protein
HLK66_RS21795	ENOG4108HW4	amino acid AbC transporter
HLK66_RS21800	ENOG4105EAB	amino acid AbC transporter
HLK66_RS21810	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HLK66_RS21815	ENOG4105EAB	amino acid AbC transporter
HLK66_RS21820	ENOG4105CHM	Aminotransferase
HLK66_RS21825	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
HLK66_RS21860	ENOG41061AU	MarR family Transcriptional regulator
HLK66_RS21870	ENOG4105DXB	Major Facilitator superfamily
HLK66_RS21875	ENOG4105DRS	transport system, permease
HLK66_RS21880	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
HLK66_RS21890	ENOG4106IQC	argininosuccinate lyase
HLK66_RS21910	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS21920	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS21930	ENOG4105C26	Dehydrogenase
HLK66_RS21935	ENOG4105FDP	GntR family transcriptional regulator
HLK66_RS21940	ENOG4107R1S	catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine
HLK66_RS21945	ENOG4108KPW	sugar kinase
HLK66_RS21955	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS21960	ENOG4105E5Q	amino acid AbC transporter
HLK66_RS21985	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS22000	ENOG4108NEV	two component transcriptional regulator, LytTR family
HLK66_RS22005	ENOG4105C2F	Histidine kinase
HLK66_RS22010	ENOG4108RTU	Aldolase
HLK66_RS22015	ENOG4108JQ1	Dehydrogenase
HLK66_RS22025	ENOG4105C5I	Dehydrogenase
HLK66_RS22030	ENOG4105DAS	pts system
HLK66_RS22070	ENOG4105BZU	Histidine kinase
HLK66_RS22100	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HLK66_RS22105	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HLK66_RS22115	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HLK66_RS22120	ENOG4105F3R	pts system mannose fructose sorbose family iid
HLK66_RS22125	ENOG4105ETZ	PTS System
HLK66_RS22130	ENOG4105KPI	PTS system sorbose subfamily IIB component
HLK66_RS22135	ENOG4105DAS	pts system
HLK66_RS22140	ENOG4105E2R	ROK family
HLK66_RS22155	ENOG4108SU4	UPF0309 protein
HLK66_RS22165	ENOG4107W9I	Creatinine amidohydrolase
HLK66_RS22175	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
HLK66_RS22185	ENOG4106ETB	IIa component
HLK66_RS22190	ENOG4106ETB	IIa component
HLK66_RS22205	ENOG4105DZC	cytosine deaminase
HLK66_RS22210	ENOG4105DZC	cytosine deaminase
HLK66_RS22220	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS22275	ENOG4105C5Y	PTS System
HLK66_RS22325	ENOG4105DKQ	ROK family
HLK66_RS22340	ENOG4108SU4	UPF0309 protein
HLK66_RS22365	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HLK66_RS22370	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
HLK66_RS22375	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HLK66_RS22385	ENOG4107RGD	Major Facilitator superfamily
HLK66_RS22400	ENOG4107TT2	Auxin Efflux Carrier
HLK66_RS22405	ENOG4105C6K	Malic enzyme
HLK66_RS22435	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HLK66_RS22445	ENOG4105CI1	PTS System
HLK66_RS22455	ENOG4105DJV	ribulose-phosphate 3-epimerase
HLK66_RS22460	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS22500	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HLK66_RS22515	ENOG4106ETB	IIa component
HLK66_RS22540	ENOG4105C0P	Mg chelatase subunit ChlI
HLK66_RS22550	ENOG4105DQ6	Transposase
HLK66_RS22585	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HLK66_RS22590	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HLK66_RS22605	ENOG4107RGC	Glycosyl transferase, family 2
HLK66_RS22630	ENOG4105EVB	acetyltransferase
HLK66_RS22640	ENOG4105D3Q	Sugar transferase
HLK66_RS22645	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HLK66_RS22650	ENOG4107YJ4	chain length determinant protein
HLK66_RS22655	ENOG4105HTX	biosynthesis protein
HLK66_RS22665	ENOG4108IMY	Transcriptional regulator
HLK66_RS22675	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HLK66_RS22690	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HLK66_RS22695	ENOG4105BZ1	(ABC) transporter
HLK66_RS22720	ENOG4105JNK	Glycosyl transferase (Group 1
HLK66_RS22765	ENOG4105JNK	Glycosyl transferase (Group 1
HLK66_RS22775	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HLK66_RS22785	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HLK66_RS22790	ENOG4108SHN	Glycosyl transferase, family 2
HLK66_RS22795	ENOG4105D3Q	Sugar transferase
HLK66_RS22800	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HLK66_RS22805	ENOG4107YJ4	chain length determinant protein
HLK66_RS22810	ENOG4105HTX	biosynthesis protein
HLK66_RS22815	ENOG4105D64	Mechanosensitive ion channel
HLK66_RS22855	ENOG4105K56	Transcriptional regulator
HLK66_RS22860	ENOG4105BZ1	(ABC) transporter
HLK66_RS22895	ENOG4105C5Y	PTS System
HLK66_RS22900	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS22910	ENOG4105VZJ	PTS System
HLK66_RS22915	ENOG4105VCP	PTS System
HLK66_RS22920	ENOG4105CK1	PTS System
HLK66_RS22940	ENOG4105KRN	Transcriptional regulator, abrb family
HLK66_RS22945	ENOG4105BZU	Histidine kinase
HLK66_RS22950	ENOG4105KK4	UPF0060 membrane protein
HLK66_RS22965	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HLK66_RS22970	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HLK66_RS22975	ENOG4105CW7	secretion protein, HlyD family
HLK66_RS22980	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS23005	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HLK66_RS23010	ENOG4105YA8	Transcriptional regulator
HLK66_RS23020	ENOG4105CPC	Aldo Keto reductase
HLK66_RS23025	ENOG41066F8	ROK family
HLK66_RS23030	ENOG4105CS2	ec 3.2.1.21
HLK66_RS23040	ENOG4105I82	acetyl xylan esterase
HLK66_RS23045	ENOG4105CMD	Transcriptional regulator, GntR family
HLK66_RS23050	ENOG4107S21	permease
HLK66_RS23060	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HLK66_RS23070	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HLK66_RS23075	ENOG41090UD	(LipO)protein
HLK66_RS23080	ENOG4105BZU	Histidine kinase
HLK66_RS23085	ENOG4107SUZ	Sodium/hydrogen exchanger family
HLK66_RS23095	ENOG4108Z7F	N-acetyltransferase
HLK66_RS23130	ENOG4105BZU	Histidine kinase
HLK66_RS23135	ENOG4105KCT	ABC transporter
HLK66_RS23140	ENOG4108M15	ABC transporter
HLK66_RS23165	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HLK66_RS23170	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLK66_RS23185	ENOG4105K4H	Nlp p60 protein
HLK66_RS23210	ENOG4105EMN	RNA polymerase sigma factor
HLK66_RS23215	ENOG4105J37	
HLK66_RS23220	ENOG4105ED1	spovr family
HLK66_RS23225	ENOG4107RVG	penicillin-binding protein
HLK66_RS23230	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HLK66_RS23245	ENOG4105KBK	Zinc finger, swim domain protein
HLK66_RS23250	ENOG4105C0D	helicase
HLK66_RS23280	ENOG4105CGA	flagellar basal-body rod protein FlgG
HLK66_RS23290	ENOG4105DFF	Rod shape-determining protein mreb
HLK66_RS23295	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
HLK66_RS23300	ENOG4105FRN	stage II sporulation protein
HLK66_RS23315	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HLK66_RS23325	ENOG4106778	Protein of unknown function (DUF1146)
HLK66_RS23330	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HLK66_RS23335	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HLK66_RS23340	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HLK66_RS23345	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HLK66_RS23350	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HLK66_RS23360	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HLK66_RS23365	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
HLK66_RS23370	ENOG41062M3	atp synthase
HLK66_RS23375	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
HLK66_RS23380	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HLK66_RS23385	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HLK66_RS23390	ENOG4108UIC	UPF0340 protein
HLK66_RS23395	ENOG4105C8Q	Methyl-accepting chemotaxis
HLK66_RS23405	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
HLK66_RS23410	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HLK66_RS23420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HLK66_RS23430	ENOG4105C26	Dehydrogenase
HLK66_RS23440	ENOG4105CC5	ABC transporter
HLK66_RS23445	ENOG4105CC5	ABC transporter
HLK66_RS23450	ENOG4105DIK	(ABC) transporter
HLK66_RS23455	ENOG4105DSE	periplasmic solute binding protein
HLK66_RS23460	ENOG4108ZXQ	stage ii sporulation protein r
HLK66_RS23465	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HLK66_RS23470	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HLK66_RS23475	ENOG4106SCS	STAS domain
HLK66_RS23480	ENOG4105C37	(CBS) domain
HLK66_RS23485	ENOG4105C37	(CBS) domain
HLK66_RS23505	ENOG4107104	thymidine kinase
HLK66_RS23510	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HLK66_RS23515	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HLK66_RS23520	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HLK66_RS23525	ENOG4105D2N	Aldolase
HLK66_RS23530	ENOG410812K	response regulator receiver protein
HLK66_RS23540	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HLK66_RS23565	ENOG4107Y7X	LytTR
HLK66_RS23570	ENOG4108IUW	ABC transporter
HLK66_RS23575	ENOG4108SDH	ABC, transporter
HLK66_RS23585	ENOG4105DA5	(ABC) transporter
HLK66_RS23610	ENOG4105C75	arginyL-tRNA synthetase
HLK66_RS23615	ENOG410684U	Domain of unknown function (DUF1934)
HLK66_RS23620	ENOG4105K4H	Nlp p60 protein
HLK66_RS23625	ENOG4105CYW	agmatinase
HLK66_RS23630	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HLK66_RS23635	ENOG4105BZ4	penicillin-binding protein
HLK66_RS23645	ENOG4105C98	muts2 protein
HLK66_RS23650	ENOG4108XFG	YwhD family
HLK66_RS23655	ENOG4108Z4T	Peptidase M50
HLK66_RS23660	ENOG41069HH	4-oxalocrotonate tautomerase
HLK66_RS23670	ENOG4105DCI	Phosphohydrolase
HLK66_RS23680	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HLK66_RS23685	ENOG4108VCI	transcription factor, rsfa family
HLK66_RS23690	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
HLK66_RS23695	ENOG4108IJ2	phosphate acetyltransferase
HLK66_RS23700	ENOG4107JTW	chlorite dismutase
HLK66_RS23725	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HLK66_RS23740	ENOG4105D06	uba thif-type nad fad binding protein
HLK66_RS23750	ENOG4108ZAF	Molybdopterin
HLK66_RS23755	ENOG4105DWF	phosphomethylpyrimidine kinase
HLK66_RS23765	ENOG4108TN2	lmbE family
HLK66_RS23780	ENOG4105J7I	hydrolase
HLK66_RS23785	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HLK66_RS23790	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HLK66_RS23795	ENOG4108JJ9	ABC, transporter
HLK66_RS23800	ENOG4108JJ8	(ABC) transporter
HLK66_RS23805	ENOG4108Z66	YbaK ebsC protein
HLK66_RS23820	ENOG4105F8D	glycoside hydrolase family 4
HLK66_RS23825	ENOG4107XM3	UPF0442 protein
HLK66_RS23830	ENOG4105DWK	Membrane
HLK66_RS23850	ENOG4105CJ1	ABC, transporter
HLK66_RS23855	ENOG4105DCF	alanine dehydrogenase
HLK66_RS23860	ENOG4108K8K	Transcriptional regulator
HLK66_RS23870	ENOG4105F8D	glycoside hydrolase family 4
HLK66_RS23875	ENOG4105VCP	PTS System
HLK66_RS23880	ENOG4105CK1	PTS System
HLK66_RS23885	ENOG4105VZJ	PTS System
HLK66_RS23900	ENOG4105D2X	ABC transporter substrate-binding protein
HLK66_RS23905	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HLK66_RS23920	ENOG4105VCP	PTS System
HLK66_RS23925	ENOG4105VZJ	PTS System
HLK66_RS23930	ENOG4105CS2	ec 3.2.1.21
HLK66_RS23940	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS23950	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HLK66_RS24000	ENOG4105G9B	Transcriptional regulator
HLK66_RS24010	ENOG41079KZ	Major Facilitator Superfamily
HLK66_RS24015	ENOG4105UQX	Mate efflux family protein
HLK66_RS24025	ENOG4105D7K	pfkb domain protein
HLK66_RS24050	ENOG4105FKQ	transcriptional regulator
HLK66_RS24060	ENOG4107URF	beta-phospho-glucomutase
HLK66_RS24075	ENOG4105EG2	ABC transporter, permease
HLK66_RS24080	ENOG4105D56	permease protein
HLK66_RS24085	ENOG4107FKK	extracellular solute-binding protein family 1
HLK66_RS24090	ENOG4105C5Y	PTS System
HLK66_RS24095	ENOG4108W7F	transporter, permease
HLK66_RS24100	ENOG4108JJB	ABC transporter
HLK66_RS24105	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
HLK66_RS24110	ENOG4105ETU	transcriptional activator (TenA
HLK66_RS24120	ENOG41080UX	Methyltransferase
HLK66_RS24125	ENOG4108IV0	ABC, transporter
HLK66_RS24130	ENOG4105C0Z	ABC transporter
HLK66_RS24135	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HLK66_RS24145	ENOG4105CP9	extracellular ligand-binding receptor
HLK66_RS24170	ENOG4108HQS	Glycine betaine
HLK66_RS24180	ENOG4105DSG	hydrolase family 43
HLK66_RS24195	ENOG4105NTD	Inherit from COG: Hydrolase
HLK66_RS24205	ENOG4105F5H	Glycosyl Hydrolase Family 88
HLK66_RS24225	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS24230	ENOG41075H3	AraC family transcriptional regulator
HLK66_RS24240	ENOG4105CTX	dehydratase
HLK66_RS24245	ENOG4105D2H	Uronic isomerase
HLK66_RS24255	ENOG4107TDE	lipolytic protein G-D-S-L family
HLK66_RS24270	ENOG4107QNK	)-transporter
HLK66_RS24300	ENOG4105E1J	oxidoreductase
HLK66_RS24305	ENOG4105CH6	catalase
HLK66_RS24335	ENOG4108MJI	response regulator
HLK66_RS24340	ENOG4105BZU	Histidine kinase
HLK66_RS24345	ENOG4105BZU	Histidine kinase
HLK66_RS24355	ENOG4108JQ7	(ABC) transporter
HLK66_RS24365	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS24370	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HLK66_RS24390	ENOG4107QM2	Aldo Keto reductase
HLK66_RS24395	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HLK66_RS24400	ENOG4105KJM	monovalent cation h antiporter subunit g
HLK66_RS24410	ENOG4105SC1	monovalent cation H antiporter subunit E
HLK66_RS24415	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HLK66_RS24420	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HLK66_RS24425	ENOG4105HC0	Na H antiporter
HLK66_RS24430	ENOG4105D65	subunit l
HLK66_RS24445	ENOG4105CUT	histidyl-tRNA synthetase
HLK66_RS24450	ENOG4106N3A	copper homeostasis protein cutc
HLK66_RS24455	ENOG4108SEA	Esterase
HLK66_RS24460	ENOG4105ETE	Transcriptional regulator (LacI family
HLK66_RS24465	ENOG4107T40	Inherit from COG: Glycosyltransferase 36
HLK66_RS24470	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
HLK66_RS24475	ENOG4105DRS	transport system, permease
HLK66_RS24480	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HLK66_RS24500	ENOG41065RQ	ADP-ribosylation crystallin J1
HLK66_RS24525	ENOG4108IUW	ABC transporter
HLK66_RS24535	ENOG4107RZC	phospholipase d
HLK66_RS24545	ENOG4108JU3	Alkyl hydroperoxide reductase
HLK66_RS24570	ENOG4105EMD	TRANSCRIPTIONal
HLK66_RS24575	ENOG4105CS2	ec 3.2.1.21
HLK66_RS24585	ENOG4105CK1	PTS System
HLK66_RS24590	ENOG4105VZJ	PTS System
HLK66_RS24595	ENOG4105DSG	hydrolase family 43
HLK66_RS24600	ENOG4105DWT	malate dehydrogenase (quinone)
HLK66_RS24605	ENOG4105D01	(LipO)protein
HLK66_RS24610	ENOG4108UMI	ABC transporter, permease
HLK66_RS24615	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HLK66_RS24620	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HLK66_RS24625	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS24635	ENOG4105X5K	response regulator receiver protein
HLK66_RS24640	ENOG4105DEN	Luciferase family
HLK66_RS24645	ENOG4105DEN	Luciferase family
HLK66_RS24655	ENOG4105BZU	Histidine kinase
HLK66_RS24675	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HLK66_RS24685	ENOG4106YBV	Methyl-accepting chemotaxis
HLK66_RS24690	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS24695	ENOG4105E5Q	amino acid AbC transporter
HLK66_RS24705	ENOG4108Y4K	DNA-binding transcriptional activator
HLK66_RS24710	ENOG4105D8G	Major Facilitator superfamily
HLK66_RS24720	ENOG4105C8J	)-transporter
HLK66_RS24725	ENOG4105C1J	atp-dependent rna helicase
HLK66_RS24730	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
HLK66_RS24735	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
HLK66_RS24740	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HLK66_RS24745	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HLK66_RS24755	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS24760	ENOG4105BZU	Histidine kinase
HLK66_RS24770	ENOG4105T38	integral membrane protein
HLK66_RS24785	ENOG4105D03	DNA-3-methyladenine glycosylase II
HLK66_RS24800	ENOG4105CDA	abc transporter atp-binding protein
HLK66_RS24805	ENOG4105E5Q	amino acid AbC transporter
HLK66_RS24810	ENOG4105EAB	amino acid AbC transporter
HLK66_RS24850	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HLK66_RS24855	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HLK66_RS24860	ENOG4107V6Q	Cyclic nucleotide-binding domain
HLK66_RS24865	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HLK66_RS24875	ENOG4108ZAF	Molybdopterin
HLK66_RS24880	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HLK66_RS24885	ENOG4105D06	uba thif-type nad fad binding protein
HLK66_RS24890	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HLK66_RS24905	ENOG4105R3A	Nitrate reductase
HLK66_RS24910	ENOG4108IUE	nitrate reductase beta subunit
HLK66_RS24920	ENOG4105E0C	molybdate abc transporter
HLK66_RS24925	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HLK66_RS24940	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HLK66_RS24950	ENOG4108PCN	EamA-like transporter family
HLK66_RS24955	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HLK66_RS25055	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HLK66_RS25065	ENOG4107QRT	dEAD DEAH box helicase
HLK66_RS25095	ENOG4105CVR	type I restriction-modification system
HLK66_RS25115	ENOG4107QKA	exodeoxyribonuclease V beta
HLK66_RS25135	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HLK66_RS25145	ENOG4105C0H	protease
HLK66_RS25150	ENOG4105Q2H	domain protein
HLK66_RS25165	ENOG4105BZU	Histidine kinase
HLK66_RS25170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HLK66_RS25195	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HLK66_RS25200	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HLK66_RS25215	ENOG4105CDU	Replicative dna helicase
HLK66_RS25220	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HLK66_RS25225	ENOG4105BZR	domain protein
HLK66_RS25240	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HLK66_RS25245	ENOG4108UUM	single-stranded DNA-binding protein
HLK66_RS25250	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HLK66_RS25260	ENOG4105C3G	gtp-binding protein
HLK66_RS25265	ENOG4105VDK	protein, conserved in bacteria
HLK66_RS25270	ENOG4105D8X	mechanosensitive ion channel
HLK66_RS25275	ENOG4108ZDA	Sporulation protein YyaC
HLK66_RS25280	ENOG4105FA0	parb-like partition protein
HLK66_RS25285	ENOG4107QJE	Chromosome Partitioning Protein
HLK66_RS25290	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
HLK66_RS25305	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HLK66_RS25310	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
HLK66_RS25315	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLK66_RS25320	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HLK66_RS25325	ENOG4105VG0	50S ribosomal protein l34
HLK66_RS25355	ENOG4107HP6	Transcriptional regulator
HLK66_RS25360	ENOG4105F27	Major Facilitator
HLK66_RS25370	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HLK66_RS25425	ENOG4107R5R	arsenical pump membrane protein
HLK66_RS25430	ENOG41082YX	Transcriptional regulator, arsr family
HLK66_RS25435	ENOG41082YX	Transcriptional regulator, arsr family
HLK66_RS25445	ENOG4105C3M	thioredoxin reductase
HLK66_RS25455	ENOG41067TZ	transcriptional regulator, MarR family
HLK66_RS25510	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HLK66_RS25690	ENOG4105HMI	Membrane
HLK66_RS25695	ENOG4105DUM	transcriptional regulator, lysR family
HLK66_RS25705	ENOG4108RAV	Conserved protein
HLK66_RS25750	ENOG4108UUM	single-stranded DNA-binding protein
HLK66_RS25775	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HLK66_RS25795	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS25805	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS25815	ENOG4105EKQ	RNA-directed DNA polymerase
HLK66_RS26055	ENOG4107Y9E	nuclease
HLK66_RS26155	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
HLK66_RS26170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HLK66_RS26185	ENOG4108J9Q	DNA ligase