locus-tag	class	description
C2I06_RS00005	COG0189	ligase activity
C2I06_RS00025	COG0561	phosphatase activity
C2I06_RS00030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2I06_RS00035	COG2252	PERMEase
C2I06_RS00040	COG4152	abc transporter atp-binding protein
C2I06_RS00045	COG1668	transmembrane transport
C2I06_RS00050	COG0420	3'-5' exonuclease activity
C2I06_RS00055	COG4717	serine-type aminopeptidase activity
C2I06_RS00090	COG1846	Transcriptional regulator
C2I06_RS00100	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C2I06_RS00105	COG0537	adenosine 5'-monophosphoramidase activity
C2I06_RS00110	COG1131	(ABC) transporter
C2I06_RS00115	COG4473	ABC transporter
C2I06_RS00125	COG1473	amidohydrolase
C2I06_RS00135	COG3069	C4-dicarboxylate transmembrane transporter activity
C2I06_RS00150	COG4585	Histidine kinase
C2I06_RS00155	COG2197	response regulator
C2I06_RS00165	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C2I06_RS00170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C2I06_RS00175	COG1309	transcriptional regulator
C2I06_RS00180	COG1511	domain protein
C2I06_RS00185	COG0095	Lipoate-protein ligase
C2I06_RS00190	COG0501	Belongs to the peptidase M48B family
C2I06_RS00210	COG4946	Tricorn protease homolog
C2I06_RS00210	COG0823	Involved in the tonB-independent uptake of proteins
C2I06_RS00210	COG1506	peptidase
C2I06_RS00220	COG0398	Pfam SNARE associated Golgi protein
C2I06_RS00230	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C2I06_RS00275	COG0179	Fumarylacetoacetate (FAA) hydrolase
C2I06_RS00285	COG4585	Histidine kinase
C2I06_RS00295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS00300	COG1253	flavin adenine dinucleotide binding
C2I06_RS00305	COG1131	(ABC) transporter
C2I06_RS00320	COG2226	methyltransferase
C2I06_RS00325	COG1131	(ABC) transporter
C2I06_RS00335	COG1737	Transcriptional regulator
C2I06_RS00340	COG0673	inositol 2-dehydrogenase activity
C2I06_RS00345	COG0673	inositol 2-dehydrogenase activity
C2I06_RS00355	COG0662	Cupin 2, conserved barrel domain protein
C2I06_RS00355	COG2207	Transcriptional regulator
C2I06_RS00370	COG1247	-acetyltransferase
C2I06_RS00380	COG0367	asparagine synthase
C2I06_RS00390	COG0697	spore germination
C2I06_RS00400	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS00405	COG1666	GTP binding
C2I06_RS00410	COG2996	Protein conserved in bacteria
C2I06_RS00425	COG1307	EDD domain protein, DegV family
C2I06_RS00430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS00445	COG0561	phosphatase activity
C2I06_RS00450	COG1073	alpha beta
C2I06_RS00455	COG2151	metal-sulfur cluster biosynthetic enzyme
C2I06_RS00460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C2I06_RS00465	COG0303	'Molybdopterin
C2I06_RS00470	COG1620	l-lactate permease
C2I06_RS00475	COG2186	Transcriptional regulator
C2I06_RS00480	COG0247	lactate metabolic process
C2I06_RS00485	COG1139	Iron-sulfur cluster binding protein
C2I06_RS00490	COG1556	Lactate utilization protein
C2I06_RS00495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C2I06_RS00500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C2I06_RS00505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C2I06_RS00525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C2I06_RS00545	COG2267	carboxylic ester hydrolase activity
C2I06_RS00555	COG1744	ABC transporter substrate-binding protein PnrA-like
C2I06_RS00565	COG3711	transcriptional antiterminator
C2I06_RS00575	COG3730	PTS system glucitol sorbitol-specific
C2I06_RS00580	COG3732	PTS system glucitol sorbitol-specific
C2I06_RS00595	COG0561	phosphatase activity
C2I06_RS00605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2I06_RS00610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2I06_RS00615	COG0735	belongs to the Fur family
C2I06_RS00620	COG5504	Zn-dependent protease
C2I06_RS00630	COG0180	Tryptophanyl-tRNA synthetase
C2I06_RS00635	COG4166	transmembrane transport
C2I06_RS00640	COG0601	transmembrane transport
C2I06_RS00645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2I06_RS00650	COG0444	Belongs to the ABC transporter superfamily
C2I06_RS00660	COG0456	acetyltransferase
C2I06_RS00665	COG1393	Belongs to the ArsC family
C2I06_RS00670	COG4862	establishment of competence for transformation
C2I06_RS00675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2I06_RS00685	COG1164	Oligoendopeptidase f
C2I06_RS00690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C2I06_RS00695	COG2346	COG2346, Truncated hemoglobins
C2I06_RS00700	COG0741	lytic transglycosylase activity
C2I06_RS00705	COG4116	CYTH
C2I06_RS00715	COG2357	RelA SpoT domain protein
C2I06_RS00725	COG0564	pseudouridine synthase activity
C2I06_RS00730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C2I06_RS00735	COG2239	Acts as a magnesium transporter
C2I06_RS00740	COG0475	glutathione-regulated potassium exporter activity
C2I06_RS00740	COG0569	domain protein
C2I06_RS00745	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C2I06_RS00775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2I06_RS00795	COG0210	DNA helicase
C2I06_RS00805	COG2323	membrane
C2I06_RS00810	COG2153	protein acetylation
C2I06_RS00815	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2I06_RS00820	COG2382	esterase
C2I06_RS00825	COG1328	CTP reductase activity
C2I06_RS00830	COG0602	queuosine metabolic process
C2I06_RS00840	COG0431	NADPH-dependent FMN reductase
C2I06_RS00855	COG0726	polysaccharide deacetylase
C2I06_RS00870	COG1737	Transcriptional regulator
C2I06_RS00875	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C2I06_RS00885	COG1070	Carbohydrate kinase
C2I06_RS00895	COG2169	Transcriptional regulator
C2I06_RS00900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C2I06_RS00905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C2I06_RS00910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C2I06_RS00915	COG1215	transferase activity, transferring glycosyl groups
C2I06_RS00920	COG1609	Transcriptional regulator
C2I06_RS00925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C2I06_RS00930	COG0363	glucosamine-6-phosphate deaminase activity
C2I06_RS00935	COG2188	Transcriptional regulator
C2I06_RS00940	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C2I06_RS00945	COG1595	DNA-templated transcription, initiation
C2I06_RS00950	COG3104	oligopeptide transport
C2I06_RS00965	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2I06_RS00975	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2I06_RS00985	COG3347	Dehydrogenase
C2I06_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS01000	COG1070	Carbohydrate kinase
C2I06_RS01005	COG4806	L-rhamnose isomerase
C2I06_RS01015	COG2972	Histidine kinase
C2I06_RS01035	COG4214	carbohydrate transport
C2I06_RS01040	COG1349	DNA-binding transcription factor activity
C2I06_RS01050	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS01055	COG0366	Alpha amylase catalytic
C2I06_RS01060	COG1263	PTS System
C2I06_RS01060	COG2190	(PTS) system
C2I06_RS01060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS01065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C2I06_RS01070	COG1442	glycosyl transferase family 8
C2I06_RS01075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2I06_RS01100	COG1216	Glycosyl transferase, family 2
C2I06_RS01105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C2I06_RS01110	COG3541	Predicted nucleotidyltransferase
C2I06_RS01120	COG1834	amidinotransferase
C2I06_RS01125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C2I06_RS01130	COG1309	transcriptional regulator
C2I06_RS01135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2I06_RS01140	COG1523	belongs to the glycosyl hydrolase 13 family
C2I06_RS01155	COG0446	pyridine nucleotide-disulphide oxidoreductase
C2I06_RS01160	COG1937	Protein conserved in bacteria
C2I06_RS01165	COG2210	Belongs to the sulfur carrier protein TusA family
C2I06_RS01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2I06_RS01185	COG5577	PFAM Coat F domain
C2I06_RS01195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C2I06_RS01200	COG3162	membrane
C2I06_RS01205	COG3546	catalase activity
C2I06_RS01210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2I06_RS01245	COG2205	protein histidine kinase activity
C2I06_RS01250	COG0745	RESPONSE REGULATOR receiver
C2I06_RS01280	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2I06_RS01285	COG0840	transmembrane signaling receptor activity
C2I06_RS01290	COG0655	NAD(P)H dehydrogenase (quinone) activity
C2I06_RS01295	COG3279	Response regulator of the LytR AlgR family
C2I06_RS01300	COG2972	Histidine kinase
C2I06_RS01310	COG1175	transmembrane transport
C2I06_RS01340	COG2814	Major facilitator Superfamily
C2I06_RS01345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS01350	COG1116	anion transmembrane transporter activity
C2I06_RS01355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2I06_RS01360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2I06_RS01365	COG0697	spore germination
C2I06_RS01370	COG1609	Transcriptional regulator
C2I06_RS01375	COG4209	transmembrane transport
C2I06_RS01380	COG0395	ABC-type sugar transport system, permease component
C2I06_RS01390	COG1621	beta-fructofuranosidase activity
C2I06_RS01395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS01400	COG1621	beta-fructofuranosidase activity
C2I06_RS01405	COG1621	beta-fructofuranosidase activity
C2I06_RS01410	COG1621	beta-fructofuranosidase activity
C2I06_RS01415	COG1653	transport
C2I06_RS01420	COG4753	response regulator
C2I06_RS01420	COG2207	Transcriptional regulator
C2I06_RS01425	COG2972	Histidine kinase
C2I06_RS01430	COG0583	DNA-binding transcription factor activity
C2I06_RS01435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2I06_RS01440	COG2271	Major facilitator Superfamily
C2I06_RS01445	COG0405	Gamma-glutamyltransferase
C2I06_RS01450	COG0840	transmembrane signaling receptor activity
C2I06_RS01460	COG0494	nUDIX hydrolase
C2I06_RS01465	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS01470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2I06_RS01475	COG2146	nitrite reductase [NAD(P)H] activity
C2I06_RS01480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C2I06_RS01480	COG1587	Uroporphyrinogen-III synthase
C2I06_RS01490	COG2116	formate transmembrane transporter activity
C2I06_RS01495	COG3604	Transcriptional regulator
C2I06_RS01505	COG2223	nitrite transmembrane transporter activity
C2I06_RS01535	COG0523	cobalamin synthesis protein
C2I06_RS01540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C2I06_RS01550	COG3588	fructose-bisphosphate aldolase
C2I06_RS01585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2I06_RS01595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS01605	COG1175	transmembrane transport
C2I06_RS01610	COG0395	ABC-type sugar transport system, permease component
C2I06_RS01620	COG0673	inositol 2-dehydrogenase activity
C2I06_RS01640	COG1082	Xylose isomerase domain protein TIM barrel
C2I06_RS01645	COG3773	Cell wall hydrolase
C2I06_RS01650	COG0515	serine threonine protein kinase
C2I06_RS01660	COG1732	Glycine betaine
C2I06_RS01670	COG2207	Transcriptional regulator
C2I06_RS01670	COG0662	Cupin 2, conserved barrel domain protein
C2I06_RS01685	COG0395	ABC-type sugar transport system, permease component
C2I06_RS01690	COG1874	Beta-galactosidase
C2I06_RS01695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C2I06_RS01700	COG3773	Cell wall hydrolase
C2I06_RS01710	COG1414	Transcriptional regulator
C2I06_RS01715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2I06_RS01720	COG0129	dihydroxy-acid dehydratase activity
C2I06_RS01730	COG3507	Belongs to the glycosyl hydrolase 43 family
C2I06_RS01740	COG0583	DNA-binding transcription factor activity
C2I06_RS01750	COG1811	Na channel or pump
C2I06_RS01760	COG3842	ATPase activity
C2I06_RS01770	COG0395	ABC-type sugar transport system, permease component
C2I06_RS01780	COG0584	glycerophosphoryl diester phosphodiesterase
C2I06_RS01785	COG0584	glycerophosphoryl diester phosphodiesterase
C2I06_RS01800	COG0142	geranyltranstransferase activity
C2I06_RS01805	COG1234	tRNA 3'-trailer cleavage
C2I06_RS01815	COG0154	amidase activity
C2I06_RS01835	COG2508	Transcriptional regulator
C2I06_RS01840	COG1953	Uracil, thiamine, allantoin
C2I06_RS01860	COG1266	CAAX protease self-immunity
C2I06_RS01870	COG0720	synthase
C2I06_RS01880	COG0302	gtp cyclohydrolase
C2I06_RS01890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C2I06_RS01915	COG0431	NADPH-dependent FMN reductase
C2I06_RS01930	COG0395	ABC-type sugar transport system, permease component
C2I06_RS01935	COG3507	Belongs to the glycosyl hydrolase 43 family
C2I06_RS01940	COG5578	integral membrane protein
C2I06_RS01945	COG3940	Belongs to the glycosyl hydrolase 43 family
C2I06_RS01970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C2I06_RS01975	COG2207	Transcriptional regulator
C2I06_RS01985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C2I06_RS02000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C2I06_RS02005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C2I06_RS02010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C2I06_RS02025	COG1113	amino acid transport
C2I06_RS02030	COG4555	ABC transporter
C2I06_RS02065	COG3850	Histidine kinase
C2I06_RS02065	COG5002	protein histidine kinase activity
C2I06_RS02070	COG1136	(ABC) transporter
C2I06_RS02080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C2I06_RS02085	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS02090	COG1595	DNA-templated transcription, initiation
C2I06_RS02110	COG0366	Alpha amylase catalytic
C2I06_RS02115	COG2017	converts alpha-aldose to the beta-anomer
C2I06_RS02120	COG1175	transmembrane transport
C2I06_RS02125	COG0395	ABC-type sugar transport system, permease component
C2I06_RS02135	COG3254	rhamnose metabolic process
C2I06_RS02140	COG5578	integral membrane protein
C2I06_RS02150	COG2972	Histidine kinase
C2I06_RS02155	COG2207	Transcriptional regulator
C2I06_RS02155	COG4753	response regulator
C2I06_RS02185	COG1266	CAAX protease self-immunity
C2I06_RS02190	COG1404	Belongs to the peptidase S8 family
C2I06_RS02195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C2I06_RS02210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2I06_RS02215	COG2169	Transcriptional regulator
C2I06_RS02225	COG0673	inositol 2-dehydrogenase activity
C2I06_RS02230	COG1082	Xylose isomerase domain protein TIM barrel
C2I06_RS02235	COG0673	inositol 2-dehydrogenase activity
C2I06_RS02240	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2I06_RS02255	COG1595	DNA-templated transcription, initiation
C2I06_RS02265	COG0772	Belongs to the SEDS family
C2I06_RS02275	COG0583	DNA-binding transcription factor activity
C2I06_RS02280	COG1063	alcohol dehydrogenase
C2I06_RS02285	COG2814	Major facilitator Superfamily
C2I06_RS02300	COG2205	protein histidine kinase activity
C2I06_RS02310	COG1252	NADH dehydrogenase
C2I06_RS02320	COG0778	Nitroreductase
C2I06_RS02330	COG4193	domain, Protein
C2I06_RS02335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2I06_RS02340	COG3883	PFAM NLP P60 protein
C2I06_RS02340	COG0791	NLP P60 protein
C2I06_RS02345	COG1121	(ABC) transporter
C2I06_RS02350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2I06_RS02370	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C2I06_RS02385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C2I06_RS02390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS02395	COG1119	ATPase activity
C2I06_RS02400	COG0561	phosphatase activity
C2I06_RS02410	COG1585	Membrane protein implicated in regulation of membrane protease activity
C2I06_RS02415	COG2268	Band 7 protein
C2I06_RS02420	COG2113	Glycine betaine
C2I06_RS02425	COG4176	ABC-type proline glycine betaine transport system permease component
C2I06_RS02430	COG0517	IMP dehydrogenase activity
C2I06_RS02430	COG4175	Glycine betaine
C2I06_RS02435	COG1510	regulation of RNA biosynthetic process
C2I06_RS02450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C2I06_RS02455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C2I06_RS02460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS02465	COG4597	amino acid ABC transporter
C2I06_RS02470	COG0765	amino acid transport
C2I06_RS02475	COG1126	abc transporter atp-binding protein
C2I06_RS02485	COG0861	Integral membrane protein TerC family
C2I06_RS02495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2I06_RS02500	COG3594	Acyltransferase
C2I06_RS02505	COG5002	protein histidine kinase activity
C2I06_RS02515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2I06_RS02520	COG0436	Aminotransferase
C2I06_RS02530	COG3852	Histidine kinase
C2I06_RS02535	COG1846	Transcriptional regulator
C2I06_RS02545	COG0542	response to heat
C2I06_RS02550	COG3949	Membrane
C2I06_RS02565	COG4873	Protein conserved in bacteria
C2I06_RS02585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2I06_RS02590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C2I06_RS02595	COG2084	Dehydrogenase
C2I06_RS02600	COG0436	Aminotransferase
C2I06_RS02620	COG0784	Response regulator, receiver
C2I06_RS02620	COG0835	chemotaxis
C2I06_RS02635	COG3300	MHYT domain
C2I06_RS02635	COG5001	Diguanylate cyclase
C2I06_RS02640	COG4990	cell redox homeostasis
C2I06_RS02645	COG2200	EAL domain
C2I06_RS02660	COG4703	Protein of unknown function (DUF1797)
C2I06_RS02665	COG0517	IMP dehydrogenase activity
C2I06_RS02670	COG0583	DNA-binding transcription factor activity
C2I06_RS02675	COG2171	N-acyltransferase activity
C2I06_RS02680	COG1473	amidohydrolase
C2I06_RS02685	COG0668	transmembrane transport
C2I06_RS02690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2I06_RS02695	COG0569	domain protein
C2I06_RS02700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C2I06_RS02705	COG5503	Protein of unknown function (DUF1447)
C2I06_RS02725	COG0022	dehydrogenase e1 component
C2I06_RS02730	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2I06_RS02750	COG1982	Orn Lys Arg decarboxylase major
C2I06_RS02760	COG4493	Belongs to the UPF0637 family
C2I06_RS02770	COG0483	inositol monophosphate 1-phosphatase activity
C2I06_RS02780	COG1217	gtp-binding protein TYPA
C2I06_RS02790	COG4896	Protein conserved in bacteria
C2I06_RS02800	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C2I06_RS02805	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C2I06_RS02815	COG0772	Belongs to the SEDS family
C2I06_RS02830	COG2340	Cysteine-rich secretory protein family
C2I06_RS02850	COG3679	Belongs to the UPF0342 family
C2I06_RS02855	COG4471	UPF0298 protein
C2I06_RS02860	COG0742	ribosomal rna small subunit methyltransferase
C2I06_RS02865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C2I06_RS02870	COG3314	Sporulation integral membrane protein YlbJ
C2I06_RS02875	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2I06_RS02880	COG1323	Belongs to the UPF0348 family
C2I06_RS02885	COG1399	metal-binding, possibly nucleic acid-binding protein
C2I06_RS02890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C2I06_RS02895	COG1683	Conserved Protein
C2I06_RS02915	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C2I06_RS02920	COG2001	Belongs to the MraZ family
C2I06_RS02935	COG0768	penicillin binding
C2I06_RS02945	COG0768	penicillin binding
C2I06_RS02950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C2I06_RS02960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2I06_RS02965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C2I06_RS02975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C2I06_RS02980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C2I06_RS02985	COG3879	Bacterial protein of unknown function (DUF881)
C2I06_RS02990	COG3879	Bacterial protein of unknown function (DUF881)
C2I06_RS02995	COG3856	small basic protein
C2I06_RS03000	COG0849	cell division
C2I06_RS03005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C2I06_RS03015	COG1191	sigma factor activity
C2I06_RS03020	COG1191	sigma factor activity
C2I06_RS03030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C2I06_RS03035	COG1799	cell septum assembly
C2I06_RS03040	COG0762	integral membrane protein
C2I06_RS03045	COG2302	S4 RNA-binding domain
C2I06_RS03050	COG3599	regulation of cell shape
C2I06_RS03055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C2I06_RS03060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2I06_RS03065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C2I06_RS03070	COG0564	pseudouridine synthase activity
C2I06_RS03075	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C2I06_RS03085	COG0540	Belongs to the ATCase OTCase family
C2I06_RS03090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C2I06_RS03100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C2I06_RS03110	COG0167	dihydroorotate dehydrogenase activity
C2I06_RS03130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C2I06_RS03135	COG1561	YicC-like family, N-terminal region
C2I06_RS03145	COG0194	GDP metabolic process
C2I06_RS03155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2I06_RS03160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C2I06_RS03180	COG3833	ABC-type maltose transport systems, permease component
C2I06_RS03190	COG3250	beta-galactosidase activity
C2I06_RS03195	COG3250	beta-galactosidase activity
C2I06_RS03205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C2I06_RS03210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C2I06_RS03210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C2I06_RS03220	COG0631	protein serine/threonine phosphatase activity
C2I06_RS03225	COG2815	serine threonine protein kinase
C2I06_RS03225	COG0515	serine threonine protein kinase
C2I06_RS03230	COG1162	GTPase activity
C2I06_RS03235	COG1564	THIamine pyrophosphokinase
C2I06_RS03245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C2I06_RS03250	COG1302	Protein conserved in bacteria
C2I06_RS03255	COG1461	Dihydroxyacetone kinase
C2I06_RS03260	COG1760	l-serine dehydratase
C2I06_RS03265	COG1760	l-serine dehydratase
C2I06_RS03270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C2I06_RS03275	COG1349	DNA-binding transcription factor activity
C2I06_RS03280	COG0416	fatty acid biosynthetic process
C2I06_RS03285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C2I06_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS03295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C2I06_RS03300	COG0571	ribonuclease III activity
C2I06_RS03305	COG1196	nuclear chromosome segregation
C2I06_RS03310	COG0552	protein localization to endoplasmic reticulum
C2I06_RS03325	COG1131	(ABC) transporter
C2I06_RS03340	COG0714	Associated with various cellular activities
C2I06_RS03360	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C2I06_RS03365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C2I06_RS03375	COG1837	Belongs to the UPF0109 family
C2I06_RS03385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C2I06_RS03400	COG0681	Belongs to the peptidase S26 family
C2I06_RS03405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C2I06_RS03420	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2I06_RS03425	COG0045	succinate-CoA ligase (ADP-forming) activity
C2I06_RS03430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C2I06_RS03435	COG0758	DNA mediated transformation
C2I06_RS03440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2I06_RS03445	COG4974	Belongs to the 'phage' integrase family
C2I06_RS03455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C2I06_RS03460	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C2I06_RS03465	COG1815	bacterial-type flagellum-dependent cell motility
C2I06_RS03470	COG1558	bacterial-type flagellum-dependent cell motility
C2I06_RS03475	COG1677	Flagellar hook-basal body complex protein FliE
C2I06_RS03480	COG1766	The M ring may be actively involved in energy transduction
C2I06_RS03485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2I06_RS03490	COG1317	bacterial-type flagellum organization
C2I06_RS03495	COG1157	protein secretion by the type III secretion system
C2I06_RS03500	COG2882	bacterial-type flagellum organization
C2I06_RS03515	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C2I06_RS03525	COG4786	Flagellar basal body rod
C2I06_RS03530	COG1582	Flagellar protein (FlbD)
C2I06_RS03535	COG1580	Controls the rotational direction of flagella during chemotaxis
C2I06_RS03540	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2I06_RS03545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C2I06_RS03545	COG1776	CheC inhibitor of MCP methylation
C2I06_RS03550	COG2201	protein-glutamate methylesterase activity
C2I06_RS03555	COG3190	flagellar
C2I06_RS03565	COG1987	bacterial-type flagellum assembly
C2I06_RS03575	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2I06_RS03580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C2I06_RS03590	COG0455	bacterial-type flagellum organization
C2I06_RS03595	COG2201	protein-glutamate methylesterase activity
C2I06_RS03600	COG0643	Histidine kinase
C2I06_RS03600	COG2198	Histidine kinase
C2I06_RS03605	COG0835	chemotaxis
C2I06_RS03610	COG1776	CheC inhibitor of MCP methylation
C2I06_RS03615	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C2I06_RS03620	COG1191	sigma factor activity
C2I06_RS03650	COG0233	cytoplasmic translational termination
C2I06_RS03660	COG4589	Belongs to the CDS family
C2I06_RS03670	COG0750	zinc metalloprotease
C2I06_RS03675	COG0442	prolyl-tRNA aminoacylation
C2I06_RS03680	COG2176	DNA-directed DNA polymerase activity
C2I06_RS03685	COG0779	Required for maturation of 30S ribosomal subunits
C2I06_RS03690	COG0195	Participates in both transcription termination and antitermination
C2I06_RS03695	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C2I06_RS03700	COG1358	cellular component organization or biogenesis
C2I06_RS03710	COG1550	Protein conserved in bacteria
C2I06_RS03720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C2I06_RS03725	COG0196	riboflavin kinase activity
C2I06_RS03730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C2I06_RS03735	COG1185	polyribonucleotide nucleotidyltransferase activity
C2I06_RS03740	COG0726	polysaccharide deacetylase
C2I06_RS03745	COG0612	Peptidase, M16
C2I06_RS03750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2I06_RS03755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C2I06_RS03760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C2I06_RS03765	COG0527	aspartate kinase activity
C2I06_RS03770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2I06_RS03775	COG1113	amino acid transport
C2I06_RS03780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C2I06_RS03785	COG0740	serine-type endopeptidase activity
C2I06_RS03800	COG1674	ftsk spoiiie
C2I06_RS03800	COG4980	gas vesicle protein
C2I06_RS03805	COG2188	Transcriptional regulator
C2I06_RS03810	COG1744	ABC transporter substrate-binding protein PnrA-like
C2I06_RS03815	COG3845	ABC transporter
C2I06_RS03820	COG4603	Belongs to the binding-protein-dependent transport system permease family
C2I06_RS03825	COG1079	Belongs to the binding-protein-dependent transport system permease family
C2I06_RS03840	COG0612	Peptidase, M16
C2I06_RS03845	COG0612	Peptidase, M16
C2I06_RS03850	COG0300	oxidoreductase activity
C2I06_RS03865	COG1426	Protein conserved in bacteria
C2I06_RS03870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C2I06_RS03875	COG1546	Belongs to the CinA family
C2I06_RS03875	COG1058	Belongs to the CinA family
C2I06_RS03880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C2I06_RS03885	COG1418	mRNA catabolic process
C2I06_RS03890	COG1692	metallophosphoesterase
C2I06_RS03895	COG2359	stage V sporulation protein S
C2I06_RS03905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C2I06_RS03910	COG4550	Control of competence regulator ComK, YlbF/YmcA
C2I06_RS03940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C2I06_RS03945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C2I06_RS03960	COG3711	transcriptional antiterminator
C2I06_RS03960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS03965	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2I06_RS04000	COG2217	Heavy metal translocating P-type atpase
C2I06_RS04005	COG0586	Pfam SNARE associated Golgi protein
C2I06_RS04020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2I06_RS04025	COG0601	transmembrane transport
C2I06_RS04035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C2I06_RS04040	COG2271	Major facilitator Superfamily
C2I06_RS04045	COG1846	Transcriptional regulator
C2I06_RS04045	COG0456	acetyltransferase
C2I06_RS04050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2I06_RS04055	COG0583	DNA-binding transcription factor activity
C2I06_RS04060	COG0662	Cupin 2, conserved barrel domain protein
C2I06_RS04060	COG2207	Transcriptional regulator
C2I06_RS04070	COG0583	DNA-binding transcription factor activity
C2I06_RS04075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C2I06_RS04080	COG1609	Transcriptional regulator
C2I06_RS04100	COG2318	DinB family
C2I06_RS04105	COG2207	Transcriptional regulator
C2I06_RS04120	COG1309	transcriptional regulator
C2I06_RS04125	COG3773	Cell wall hydrolase
C2I06_RS04170	COG0531	amino acid
C2I06_RS04185	COG0640	Transcriptional regulator
C2I06_RS04210	COG3848	Pyruvate phosphate dikinase
C2I06_RS04210	COG0574	Belongs to the PEP-utilizing enzyme family
C2I06_RS04215	COG1794	racemase activity, acting on amino acids and derivatives
C2I06_RS04220	COG0076	glutamate decarboxylase activity
C2I06_RS04235	COG0768	penicillin binding
C2I06_RS04240	COG0768	penicillin binding
C2I06_RS04270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C2I06_RS04270	COG0723	plastoquinol--plastocyanin reductase activity
C2I06_RS04310	COG3715	PTS system
C2I06_RS04315	COG3716	PTS system mannose fructose sorbose family IID component
C2I06_RS04320	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS04320	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS04325	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2I06_RS04360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C2I06_RS04370	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS04380	COG3708	Transcriptional regulator
C2I06_RS04380	COG2207	Transcriptional regulator
C2I06_RS04385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2I06_RS04410	COG3546	catalase activity
C2I06_RS04435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2I06_RS04465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2I06_RS04470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C2I06_RS04475	COG0217	transcriptional regulatory protein
C2I06_RS04490	COG0789	Transcriptional regulator
C2I06_RS04515	COG0697	spore germination
C2I06_RS04530	COG0531	amino acid
C2I06_RS04550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C2I06_RS04560	COG0454	-acetyltransferase
C2I06_RS04575	COG2318	DinB family
C2I06_RS04620	COG0596	Alpha beta hydrolase
C2I06_RS04635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS04665	COG0640	Transcriptional regulator
C2I06_RS04670	COG2814	Major facilitator Superfamily
C2I06_RS04680	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS04685	COG1309	transcriptional regulator
C2I06_RS04690	COG2814	Major facilitator Superfamily
C2I06_RS04710	COG5002	protein histidine kinase activity
C2I06_RS04725	COG1011	Hydrolase
C2I06_RS04790	COG2207	Transcriptional regulator
C2I06_RS04790	COG3708	Transcriptional regulator
C2I06_RS04800	COG0018	arginyl-trna synthetase
C2I06_RS04805	COG4549	nuclear export factor GLE1
C2I06_RS04830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS04840	COG0592	DNA-directed DNA polymerase activity
C2I06_RS04845	COG2329	Antibiotic biosynthesis monooxygenase
C2I06_RS04890	COG4106	trans-aconitate 2-methyltransferase activity
C2I06_RS04900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS04925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C2I06_RS04930	COG0022	dehydrogenase e1 component
C2I06_RS04935	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2I06_RS04940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2I06_RS04945	COG0316	Belongs to the HesB IscA family
C2I06_RS04980	COG3655	Transcriptional regulator
C2I06_RS04985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C2I06_RS05000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2I06_RS05010	COG0288	reversible hydration of carbon dioxide
C2I06_RS05015	COG5609	conserved protein (DUF2294)
C2I06_RS05065	COG2076	Multidrug Resistance protein
C2I06_RS05070	COG2076	Multidrug Resistance protein
C2I06_RS05075	COG1309	transcriptional regulator
C2I06_RS05095	COG0412	Dienelactone hydrolase
C2I06_RS05110	COG0583	DNA-binding transcription factor activity
C2I06_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS05165	COG5002	protein histidine kinase activity
C2I06_RS05175	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2I06_RS05240	COG2244	polysaccharide biosynthetic process
C2I06_RS05280	COG1104	cysteine desulfurase activity
C2I06_RS05285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C2I06_RS05290	COG0157	Belongs to the NadC ModD family
C2I06_RS05295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C2I06_RS05305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C2I06_RS05315	COG0464	growth
C2I06_RS05320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C2I06_RS05330	COG0789	Transcriptional regulator
C2I06_RS05335	COG0174	glutamine synthetase
C2I06_RS05375	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C2I06_RS05415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C2I06_RS05425	COG2080	2 iron, 2 sulfur cluster binding
C2I06_RS05440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2I06_RS05445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2I06_RS05455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2I06_RS05460	COG4224	UPF0291 protein
C2I06_RS05475	COG3763	UPF0154 protein
C2I06_RS05480	COG1132	(ABC) transporter
C2I06_RS05485	COG1132	(ABC) transporter
C2I06_RS05495	COG0785	Cytochrome C biogenesis protein
C2I06_RS05500	COG2201	protein-glutamate methylesterase activity
C2I06_RS05505	COG4846	Membrane protein involved in cytochrome C biogenesis
C2I06_RS05540	COG0420	3'-5' exonuclease activity
C2I06_RS05545	COG0419	ATPase involved in DNA repair
C2I06_RS05550	COG1876	peptidase activity
C2I06_RS05555	COG1363	Peptidase, m42
C2I06_RS05560	COG1368	sulfuric ester hydrolase activity
C2I06_RS05565	COG3973	AAA domain
C2I06_RS05570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2I06_RS05580	COG3764	Sortase (surface protein transpeptidase)
C2I06_RS05595	COG0456	acetyltransferase
C2I06_RS05600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS05615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2I06_RS05625	COG5577	PFAM Coat F domain
C2I06_RS05630	COG1063	alcohol dehydrogenase
C2I06_RS05640	COG5577	PFAM Coat F domain
C2I06_RS05660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C2I06_RS05665	COG1247	-acetyltransferase
C2I06_RS05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS05690	COG1227	inorganic diphosphatase activity
C2I06_RS05695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2I06_RS05710	COG0464	growth
C2I06_RS05730	COG4841	protein insertion into membrane
C2I06_RS05735	COG2843	Capsule synthesis protein
C2I06_RS05740	COG3852	Histidine kinase
C2I06_RS05745	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C2I06_RS05760	COG1960	acyl-CoA dehydrogenase activity
C2I06_RS05765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2I06_RS05765	COG3153	acetyltransferase
C2I06_RS05770	COG0456	acetyltransferase
C2I06_RS05775	COG5504	Zn-dependent protease
C2I06_RS05780	COG1846	Transcriptional regulator
C2I06_RS05785	COG0477	Major facilitator Superfamily
C2I06_RS05805	COG0646	methionine synthase
C2I06_RS05805	COG1410	methionine synthase
C2I06_RS05810	COG0646	methionine synthase
C2I06_RS05810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C2I06_RS05815	COG0626	cystathionine gamma-synthase activity
C2I06_RS05820	COG0626	cystathionine gamma-synthase activity
C2I06_RS05830	COG0745	RESPONSE REGULATOR receiver
C2I06_RS05835	COG5002	protein histidine kinase activity
C2I06_RS05840	COG0567	Dehydrogenase, E1 component
C2I06_RS05845	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2I06_RS05860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C2I06_RS05880	COG1335	isochorismatase
C2I06_RS05885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C2I06_RS05895	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C2I06_RS05910	COG1686	Belongs to the peptidase S11 family
C2I06_RS05915	COG0488	(ABC) transporter
C2I06_RS05920	COG2116	formate transmembrane transporter activity
C2I06_RS05950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C2I06_RS05960	COG5002	protein histidine kinase activity
C2I06_RS05965	COG3584	3D domain protein
C2I06_RS05965	COG1388	LysM domain
C2I06_RS05980	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C2I06_RS05985	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C2I06_RS05995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C2I06_RS06000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C2I06_RS06005	COG2080	2 iron, 2 sulfur cluster binding
C2I06_RS06010	COG3195	allantoin biosynthetic process
C2I06_RS06010	COG3648	Uricase
C2I06_RS06015	COG2351	hydroxyisourate hydrolase activity
C2I06_RS06020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C2I06_RS06030	COG2223	nitrite transmembrane transporter activity
C2I06_RS06045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2I06_RS06055	COG0561	phosphatase activity
C2I06_RS06065	COG1164	Oligoendopeptidase f
C2I06_RS06070	COG0583	DNA-binding transcription factor activity
C2I06_RS06075	COG0067	glutamate synthase
C2I06_RS06075	COG0069	glutamate synthase activity
C2I06_RS06075	COG0070	glutamate synthase
C2I06_RS06080	COG0493	'glutamate synthase
C2I06_RS06085	COG1418	mRNA catabolic process
C2I06_RS06095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2I06_RS06100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C2I06_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS06110	COG0861	Integral membrane protein TerC family
C2I06_RS06115	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C2I06_RS06130	COG0681	Belongs to the peptidase S26 family
C2I06_RS06140	COG1725	Transcriptional regulator
C2I06_RS06155	COG4974	Belongs to the 'phage' integrase family
C2I06_RS06170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C2I06_RS06175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C2I06_RS06175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C2I06_RS06180	COG0307	riboflavin synthase, alpha
C2I06_RS06185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2I06_RS06190	COG0708	Exodeoxyribonuclease III
C2I06_RS06195	COG0346	lactoylglutathione lyase activity
C2I06_RS06200	COG0561	phosphatase activity
C2I06_RS06220	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS06245	COG1733	regulation of RNA biosynthetic process
C2I06_RS06250	COG2249	NAD(P)H dehydrogenase (quinone) activity
C2I06_RS06260	COG2027	D-alanyl-D-alanine carboxypeptidase
C2I06_RS06270	COG3341	Caulimovirus viroplasmin
C2I06_RS06270	COG0328	RNA-DNA hybrid ribonuclease activity
C2I06_RS06275	COG3275	phosphorelay sensor kinase activity
C2I06_RS06285	COG1966	Carbon starvation protein
C2I06_RS06295	COG2066	Belongs to the glutaminase family
C2I06_RS06300	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C2I06_RS06310	COG0840	transmembrane signaling receptor activity
C2I06_RS06320	COG1280	lysine exporter protein (LysE YggA)
C2I06_RS06325	COG0024	Methionine aminopeptidase
C2I06_RS06335	COG0531	amino acid
C2I06_RS06355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2I06_RS06355	COG1042	CoA-binding domain protein
C2I06_RS06355	COG0045	succinate-CoA ligase (ADP-forming) activity
C2I06_RS06360	COG0753	catalase activity
C2I06_RS06365	COG0326	Molecular chaperone. Has ATPase activity
C2I06_RS06370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2I06_RS06375	COG1280	lysine exporter protein (LysE YggA)
C2I06_RS06420	COG3689	TIGRFAM TIGR03943 family protein
C2I06_RS06425	COG0701	Predicted permease
C2I06_RS06440	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS06445	COG1609	Transcriptional regulator
C2I06_RS06450	COG1621	beta-fructofuranosidase activity
C2I06_RS06465	COG0583	DNA-binding transcription factor activity
C2I06_RS06470	COG0730	response to heat
C2I06_RS06480	COG1349	DNA-binding transcription factor activity
C2I06_RS06485	COG4977	sequence-specific DNA binding
C2I06_RS06500	COG1051	belongs to the nudix hydrolase family
C2I06_RS06505	COG4473	ABC transporter
C2I06_RS06510	COG1131	(ABC) transporter
C2I06_RS06515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C2I06_RS06560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C2I06_RS06565	COG0187	DNA topoisomerase II activity
C2I06_RS06570	COG1832	CoA-binding protein
C2I06_RS06575	COG0840	transmembrane signaling receptor activity
C2I06_RS06595	COG3859	Proton-coupled thiamine transporter YuaJ
C2I06_RS06605	COG1309	transcriptional regulator
C2I06_RS06620	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2I06_RS06625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C2I06_RS06630	COG0204	Acyl-transferase
C2I06_RS06635	COG0561	phosphatase activity
C2I06_RS06640	COG1349	DNA-binding transcription factor activity
C2I06_RS06655	COG1482	cell wall glycoprotein biosynthetic process
C2I06_RS06660	COG1404	Belongs to the peptidase S8 family
C2I06_RS06670	COG2814	Major facilitator Superfamily
C2I06_RS06695	COG1268	BioY protein
C2I06_RS06700	COG1276	copper resistance
C2I06_RS06700	COG2372	response to copper ion
C2I06_RS06715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2I06_RS06720	COG0737	Belongs to the 5'-nucleotidase family
C2I06_RS06730	COG0561	phosphatase activity
C2I06_RS06740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2I06_RS06745	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C2I06_RS06760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS06770	COG1011	Hydrolase
C2I06_RS06775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C2I06_RS06805	COG1695	Transcriptional regulator
C2I06_RS06815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C2I06_RS06820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C2I06_RS06825	COG0561	phosphatase activity
C2I06_RS06830	COG0697	spore germination
C2I06_RS06835	COG1132	(ABC) transporter
C2I06_RS06840	COG0583	DNA-binding transcription factor activity
C2I06_RS06865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2I06_RS06870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C2I06_RS06870	COG0512	Glutamine amidotransferase of anthranilate synthase
C2I06_RS06875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2I06_RS06885	COG2814	Major facilitator Superfamily
C2I06_RS06890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2I06_RS06890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2I06_RS06890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS06895	COG1105	Belongs to the carbohydrate kinase PfkB family
C2I06_RS06900	COG1349	DNA-binding transcription factor activity
C2I06_RS06915	COG2176	DNA-directed DNA polymerase activity
C2I06_RS06925	COG0004	ammonium transporteR
C2I06_RS06940	COG0351	phosphomethylpyrimidine kinase
C2I06_RS06955	COG0701	Predicted permease
C2I06_RS06960	COG0523	cobalamin synthesis protein
C2I06_RS06965	COG0840	transmembrane signaling receptor activity
C2I06_RS06975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C2I06_RS07010	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C2I06_RS07015	COG1737	Transcriptional regulator
C2I06_RS07030	COG1609	Transcriptional regulator
C2I06_RS07040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C2I06_RS07045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C2I06_RS07050	COG0523	cobalamin synthesis protein
C2I06_RS07095	COG2849	repeat protein
C2I06_RS07165	COG3739	integral membrane protein
C2I06_RS07170	COG3655	Transcriptional regulator
C2I06_RS07185	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C2I06_RS07190	COG5646	InterPro IPR014922
C2I06_RS07220	COG1595	DNA-templated transcription, initiation
C2I06_RS07235	COG1357	PFAM Pentapeptide repeats (8 copies)
C2I06_RS07265	COG2733	membrane
C2I06_RS07295	COG2207	Transcriptional regulator
C2I06_RS07295	COG3708	Transcriptional regulator
C2I06_RS07300	COG1115	amino acid carrier protein
C2I06_RS07330	COG1690	Belongs to the RtcB family
C2I06_RS07335	COG4377	Putative membrane peptidase family (DUF2324)
C2I06_RS07350	COG0586	Pfam SNARE associated Golgi protein
C2I06_RS07370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2I06_RS07380	COG0406	alpha-ribazole phosphatase activity
C2I06_RS07385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2I06_RS07430	COG0726	polysaccharide deacetylase
C2I06_RS07450	COG0583	DNA-binding transcription factor activity
C2I06_RS07460	COG1346	cytolysis
C2I06_RS07485	COG0513	Belongs to the DEAD box helicase family
C2I06_RS07495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C2I06_RS07500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C2I06_RS07510	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C2I06_RS07515	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C2I06_RS07520	COG0671	phosphoesterase, PA-phosphatase related
C2I06_RS07525	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C2I06_RS07530	COG1793	dna ligase
C2I06_RS07530	COG3285	dna ligase
C2I06_RS07540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C2I06_RS07545	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C2I06_RS07575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C2I06_RS07580	COG0640	Transcriptional regulator
C2I06_RS07585	COG0534	Mate efflux family protein
C2I06_RS07610	COG2340	Cysteine-rich secretory protein family
C2I06_RS07625	COG0523	cobalamin synthesis protein
C2I06_RS07630	COG0793	Belongs to the peptidase S41A family
C2I06_RS07630	COG3409	Peptidoglycan-binding domain 1 protein
C2I06_RS07635	COG1876	peptidase activity
C2I06_RS07655	COG4479	Belongs to the UPF0346 family
C2I06_RS07665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C2I06_RS07690	COG2755	lipolytic protein G-D-S-L family
C2I06_RS07695	COG5002	protein histidine kinase activity
C2I06_RS07700	COG1307	EDD domain protein, DegV family
C2I06_RS07705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C2I06_RS07710	COG1272	protein, Hemolysin III
C2I06_RS07715	COG3716	PTS system mannose fructose sorbose family IID component
C2I06_RS07720	COG3715	PTS system
C2I06_RS07725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS07740	COG2188	Transcriptional regulator
C2I06_RS07745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C2I06_RS07760	COG2310	stress, protein
C2I06_RS07765	COG2310	stress, protein
C2I06_RS07770	COG3853	Toxic anion resistance protein (TelA)
C2I06_RS07790	COG1358	cellular component organization or biogenesis
C2I06_RS07805	COG0861	Integral membrane protein TerC family
C2I06_RS07810	COG2310	stress, protein
C2I06_RS07820	COG2136	Putative SAM-dependent methyltransferase
C2I06_RS07820	COG2521	methyltransferase
C2I06_RS07830	COG1413	lyase activity
C2I06_RS07835	COG0488	(ABC) transporter
C2I06_RS07840	COG1418	mRNA catabolic process
C2I06_RS07860	COG0386	Belongs to the glutathione peroxidase family
C2I06_RS07870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C2I06_RS07875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C2I06_RS07890	COG1321	iron dependent repressor
C2I06_RS07920	COG4129	membrane
C2I06_RS07935	COG1278	Cold shock
C2I06_RS07945	COG0328	RNA-DNA hybrid ribonuclease activity
C2I06_RS07950	COG0328	RNA-DNA hybrid ribonuclease activity
C2I06_RS07960	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C2I06_RS07970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C2I06_RS07980	COG1131	(ABC) transporter
C2I06_RS07995	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C2I06_RS08005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C2I06_RS08010	COG1199	ATP-dependent helicase activity
C2I06_RS08015	COG0116	Belongs to the methyltransferase superfamily
C2I06_RS08030	COG4474	Belongs to the UPF0398 family
C2I06_RS08040	COG3359	exonuclease
C2I06_RS08045	COG1111	helicase
C2I06_RS08045	COG1205	dead DEAH box helicase
C2I06_RS08050	COG2267	carboxylic ester hydrolase activity
C2I06_RS08055	COG0071	Belongs to the small heat shock protein (HSP20) family
C2I06_RS08085	COG3331	DNA recombination
C2I06_RS08090	COG4499	WXG100 protein secretion system (Wss), protein YukC
C2I06_RS08090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2I06_RS08100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C2I06_RS08105	COG3935	DnaD domain protein
C2I06_RS08110	COG0017	Asparaginyl-tRNA synthetase
C2I06_RS08115	COG0436	Aminotransferase
C2I06_RS08125	COG1199	ATP-dependent helicase activity
C2I06_RS08125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C2I06_RS08130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C2I06_RS08135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C2I06_RS08150	COG0617	tRNA 3'-terminal CCA addition
C2I06_RS08155	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS08160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2I06_RS08165	COG1803	Methylglyoxal synthase
C2I06_RS08170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C2I06_RS08175	COG1694	Mazg nucleotide pyrophosphohydrolase
C2I06_RS08180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS08190	COG2223	nitrite transmembrane transporter activity
C2I06_RS08195	COG2738	Putative neutral zinc metallopeptidase
C2I06_RS08205	COG4347	Protein of unknown function (DUF1405)
C2I06_RS08210	COG5582	Belongs to the UPF0302 family
C2I06_RS08215	COG0457	Tetratricopeptide repeat
C2I06_RS08225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C2I06_RS08230	COG0287	Prephenate dehydrogenase
C2I06_RS08235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C2I06_RS08240	COG4401	Chorismate mutase type I
C2I06_RS08255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C2I06_RS08260	COG0105	UTP biosynthetic process
C2I06_RS08265	COG0142	geranyltranstransferase activity
C2I06_RS08270	COG2226	methyltransferase
C2I06_RS08275	COG0142	geranyltranstransferase activity
C2I06_RS08280	COG0776	regulation of translation
C2I06_RS08285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C2I06_RS08290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C2I06_RS08295	COG1160	GTP binding
C2I06_RS08320	COG0539	negative regulation of cytoplasmic translation
C2I06_RS08335	COG2959	enzyme of heme biosynthesis
C2I06_RS08340	COG3773	Cell wall hydrolase
C2I06_RS08340	COG3409	Peptidoglycan-binding domain 1 protein
C2I06_RS08345	COG2339	peptidase activity
C2I06_RS08350	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS08355	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C2I06_RS08360	COG4862	establishment of competence for transformation
C2I06_RS08365	COG1408	metallophosphoesterase
C2I06_RS08380	COG3546	catalase activity
C2I06_RS08395	COG1266	CAAX protease self-immunity
C2I06_RS08400	COG0514	ATP-dependent DNA helicase (RecQ)
C2I06_RS08410	COG1141	Ferredoxin
C2I06_RS08415	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C2I06_RS08420	COG0739	heme binding
C2I06_RS08435	COG1595	DNA-templated transcription, initiation
C2I06_RS08440	COG5002	protein histidine kinase activity
C2I06_RS08445	COG0745	RESPONSE REGULATOR receiver
C2I06_RS08455	COG0700	Nucleoside recognition
C2I06_RS08460	COG2715	membrane protein required for spore maturation
C2I06_RS08465	COG1686	Belongs to the peptidase S11 family
C2I06_RS08470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C2I06_RS08475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C2I06_RS08480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C2I06_RS08485	COG1547	Domain of unknown function (DUF309)
C2I06_RS08495	COG4086	secreted protein
C2I06_RS08505	COG0697	spore germination
C2I06_RS08530	COG2172	sigma factor antagonist activity
C2I06_RS08540	COG1686	Belongs to the peptidase S11 family
C2I06_RS08545	COG0024	Methionine aminopeptidase
C2I06_RS08550	COG1595	DNA-templated transcription, initiation
C2I06_RS08570	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C2I06_RS08600	COG4974	Belongs to the 'phage' integrase family
C2I06_RS08610	COG0735	belongs to the Fur family
C2I06_RS08615	COG1300	Membrane
C2I06_RS08625	COG1379	DNA repair
C2I06_RS08640	COG0667	Aldo Keto reductase
C2I06_RS08660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS08665	COG0456	acetyltransferase
C2I06_RS08670	COG0346	lactoylglutathione lyase activity
C2I06_RS08675	COG1078	dGTPase activity
C2I06_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS08725	COG1063	alcohol dehydrogenase
C2I06_RS08730	COG4948	Mandelate Racemase Muconate Lactonizing
C2I06_RS08780	COG1595	DNA-templated transcription, initiation
C2I06_RS08810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS08815	COG3620	sequence-specific DNA binding
C2I06_RS08845	COG1764	response to oxidative stress
C2I06_RS08850	COG1073	alpha beta
C2I06_RS08855	COG2814	Major facilitator Superfamily
C2I06_RS08860	COG0640	Transcriptional regulator
C2I06_RS08905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C2I06_RS08910	COG2814	Major facilitator Superfamily
C2I06_RS08915	COG1846	Transcriptional regulator
C2I06_RS08925	COG0300	oxidoreductase activity
C2I06_RS08935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2I06_RS08940	COG1234	tRNA 3'-trailer cleavage
C2I06_RS08945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C2I06_RS08950	COG1408	metallophosphoesterase
C2I06_RS08960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C2I06_RS08965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C2I06_RS08975	COG2195	Cleaves the N-terminal amino acid of tripeptides
C2I06_RS08980	COG1376	ErfK ybiS ycfS ynhG family protein
C2I06_RS08985	COG1126	abc transporter atp-binding protein
C2I06_RS08990	COG0765	amino acid transport
C2I06_RS08995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS09005	COG0508	dehydrogenase complex catalyzes the overall conversion of
C2I06_RS09010	COG0022	dehydrogenase e1 component
C2I06_RS09015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C2I06_RS09020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C2I06_RS09025	COG3426	butyrate kinase activity
C2I06_RS09030	COG3290	protein histidine kinase activity
C2I06_RS09030	COG3829	transcription factor binding
C2I06_RS09035	COG0584	glycerophosphoryl diester phosphodiesterase
C2I06_RS09050	COG0745	RESPONSE REGULATOR receiver
C2I06_RS09055	COG1575	Belongs to the MenA family. Type 1 subfamily
C2I06_RS09060	COG0750	zinc metalloprotease
C2I06_RS09065	COG0497	DNA recombination
C2I06_RS09070	COG1438	arginine binding
C2I06_RS09075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C2I06_RS09080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C2I06_RS09085	COG0142	geranyltranstransferase activity
C2I06_RS09090	COG1722	exodeoxyribonuclease VII activity
C2I06_RS09105	COG1302	Protein conserved in bacteria
C2I06_RS09115	COG0511	ligase activity, forming carbon-carbon bonds
C2I06_RS09155	COG3854	ATPases associated with a variety of cellular activities
C2I06_RS09165	COG1785	Belongs to the alkaline phosphatase family
C2I06_RS09175	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS09180	COG1501	Belongs to the glycosyl hydrolase 31 family
C2I06_RS09195	COG0395	ABC-type sugar transport system, permease component
C2I06_RS09200	COG4209	transmembrane transport
C2I06_RS09215	COG2207	Transcriptional regulator
C2I06_RS09215	COG4753	response regulator
C2I06_RS09220	COG2972	Histidine kinase
C2I06_RS09240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C2I06_RS09245	COG0006	proline dipeptidase activity
C2I06_RS09255	COG3872	metal-dependent enzyme
C2I06_RS09265	COG1752	Esterase of the alpha-beta hydrolase superfamily
C2I06_RS09300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2I06_RS09305	COG0095	Lipoate-protein ligase
C2I06_RS09310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2I06_RS09315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C2I06_RS09320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C2I06_RS09325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C2I06_RS09330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C2I06_RS09365	COG4537	Required for transformation and DNA binding
C2I06_RS09370	COG1459	type II secretion system
C2I06_RS09375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2I06_RS09410	COG1388	LysM domain
C2I06_RS09410	COG1705	Flagellar rod assembly protein muramidase FlgJ
C2I06_RS09605	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C2I06_RS09620	COG1484	DNA-dependent DNA replication
C2I06_RS09630	COG3723	Recombinational DNA repair protein, rece pathway
C2I06_RS09635	COG5377	YqaJ viral recombinase family
C2I06_RS09660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2I06_RS09685	COG2072	flavoprotein involved in K transport
C2I06_RS09695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2I06_RS09700	COG0011	TIGRFAM Protein of
C2I06_RS09715	COG1368	sulfuric ester hydrolase activity
C2I06_RS09720	COG1940	carbohydrate kinase activity
C2I06_RS09735	COG0457	Tetratricopeptide repeat
C2I06_RS09735	COG0705	Rhomboid family
C2I06_RS09740	COG2318	DinB family
C2I06_RS09755	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C2I06_RS09760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C2I06_RS09790	COG0704	Plays a role in the regulation of phosphate uptake
C2I06_RS09795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2I06_RS09800	COG0581	inorganic phosphate transmembrane transporter activity
C2I06_RS09805	COG0573	inorganic phosphate transmembrane transporter activity
C2I06_RS09810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C2I06_RS09815	COG0768	penicillin binding
C2I06_RS09825	COG0477	Major facilitator Superfamily
C2I06_RS09835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2I06_RS09840	COG2839	Protein conserved in bacteria
C2I06_RS09845	COG5521	maltodextrose utilization protein MalA
C2I06_RS09860	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C2I06_RS09870	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C2I06_RS09875	COG0735	belongs to the Fur family
C2I06_RS09885	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C2I06_RS09890	COG0513	Belongs to the DEAD box helicase family
C2I06_RS09900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C2I06_RS09905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C2I06_RS09910	COG2384	SAM-dependent methyltransferase
C2I06_RS09920	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C2I06_RS09925	COG0358	DNA primase activity
C2I06_RS09930	COG1671	Belongs to the UPF0178 family
C2I06_RS09940	COG0517	IMP dehydrogenase activity
C2I06_RS09945	COG0751	glycine-tRNA ligase activity
C2I06_RS09960	COG1381	Involved in DNA repair and RecF pathway recombination
C2I06_RS09970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C2I06_RS09975	COG0295	cytidine deaminase activity
C2I06_RS09980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C2I06_RS09990	COG1480	7TM receptor with intracellular HD hydrolase
C2I06_RS09995	COG1702	phosphate starvation-inducible protein PhoH
C2I06_RS10015	COG4864	UPF0365 protein
C2I06_RS10020	COG1030	water channel activity
C2I06_RS10025	COG1610	YqeY-like protein
C2I06_RS10035	COG1283	sodium-dependent phosphate transmembrane transporter activity
C2I06_RS10045	COG1132	(ABC) transporter
C2I06_RS10050	COG1132	(ABC) transporter
C2I06_RS10055	COG1917	Cupin 2, conserved barrel domain protein
C2I06_RS10055	COG2207	Transcriptional regulator
C2I06_RS10060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C2I06_RS10065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C2I06_RS10070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C2I06_RS10075	COG2264	protein methyltransferase activity
C2I06_RS10085	COG0443	Heat shock 70 kDa protein
C2I06_RS10090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C2I06_RS10095	COG1420	regulation of RNA biosynthetic process
C2I06_RS10100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C2I06_RS10105	COG0481	GTPase activity
C2I06_RS10115	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C2I06_RS10120	COG0268	Binds directly to 16S ribosomal RNA
C2I06_RS10125	COG1466	dna polymerase III delta subunit
C2I06_RS10130	COG2333	competence protein COMEC
C2I06_RS10130	COG0658	competence protein
C2I06_RS10135	COG2131	deaminase
C2I06_RS10140	COG1596	polysaccharide export
C2I06_RS10140	COG1555	photosystem II stabilization
C2I06_RS10145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2I06_RS10150	COG2226	methyltransferase
C2I06_RS10155	COG0799	negative regulation of ribosome biogenesis
C2I06_RS10160	COG1713	HD superfamily hydrolase involved in NAD metabolism
C2I06_RS10165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C2I06_RS10170	COG1534	Rna-binding protein
C2I06_RS10180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C2I06_RS10185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C2I06_RS10195	COG0688	phosphatidylethanolamine metabolic process
C2I06_RS10200	COG1183	phosphatidylcholine synthase activity
C2I06_RS10215	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2I06_RS10235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2I06_RS10295	COG5492	domain, Protein
C2I06_RS10300	COG5492	domain, Protein
C2I06_RS10330	COG3728	DNA packaging
C2I06_RS10330	COG5484	DNA packaging
C2I06_RS10385	COG4977	sequence-specific DNA binding
C2I06_RS10390	COG0673	inositol 2-dehydrogenase activity
C2I06_RS10400	COG0673	inositol 2-dehydrogenase activity
C2I06_RS10410	COG0789	Transcriptional regulator
C2I06_RS10445	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
C2I06_RS10460	COG0626	cystathionine gamma-synthase activity
C2I06_RS10465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2I06_RS10470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C2I06_RS10475	COG2226	methyltransferase
C2I06_RS10490	COG0768	penicillin binding
C2I06_RS10495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C2I06_RS10500	COG0572	uridine kinase
C2I06_RS10505	COG0826	peptidase U32
C2I06_RS10510	COG0826	peptidase U32
C2I06_RS10515	COG4122	O-methyltransferase activity
C2I06_RS10520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C2I06_RS10525	COG3906	Belongs to the UPF0473 family
C2I06_RS10535	COG4472	Bacterial protein of unknown function (DUF965)
C2I06_RS10545	COG0628	permease
C2I06_RS10560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C2I06_RS10575	COG1104	cysteine desulfurase activity
C2I06_RS10580	COG1959	2 iron, 2 sulfur cluster binding
C2I06_RS10585	COG2364	Membrane
C2I06_RS10590	COG1473	amidohydrolase
C2I06_RS10600	COG4948	Mandelate Racemase Muconate Lactonizing
C2I06_RS10635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C2I06_RS10640	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C2I06_RS10645	COG1131	(ABC) transporter
C2I06_RS10650	COG1131	(ABC) transporter
C2I06_RS10655	COG1725	Transcriptional regulator
C2I06_RS10665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C2I06_RS10670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C2I06_RS10675	COG0124	histidyl-tRNA synthetase
C2I06_RS10680	COG3103	Sh3 type 3 domain protein
C2I06_RS10680	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2I06_RS10680	COG4991	sh3 domain protein
C2I06_RS10690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C2I06_RS10695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C2I06_RS10700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C2I06_RS10700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C2I06_RS10705	COG5416	Lipopolysaccharide assembly protein A domain
C2I06_RS10710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2I06_RS10710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C2I06_RS10720	COG2244	polysaccharide biosynthetic process
C2I06_RS10725	COG2323	membrane
C2I06_RS10735	COG1862	Preprotein translocase
C2I06_RS10745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C2I06_RS10790	COG1827	regulation of RNA biosynthetic process
C2I06_RS10795	COG0077	Prephenate dehydratase
C2I06_RS10800	COG4492	Belongs to the UPF0735 family
C2I06_RS10805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C2I06_RS10810	COG3290	protein histidine kinase activity
C2I06_RS10815	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C2I06_RS10820	COG2868	ribosomal protein
C2I06_RS10825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C2I06_RS10835	COG1994	Peptidase M50
C2I06_RS10840	COG0739	heme binding
C2I06_RS10845	COG2894	cell division
C2I06_RS10850	COG0850	regulation of cytokinetic process
C2I06_RS10855	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C2I06_RS10860	COG1792	Involved in formation and maintenance of cell shape
C2I06_RS10865	COG1077	Cell shape determining protein MreB Mrl
C2I06_RS10870	COG2003	Belongs to the UPF0758 family
C2I06_RS10875	COG0424	maF-like protein
C2I06_RS10905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C2I06_RS10915	COG1459	type II secretion system
C2I06_RS10925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C2I06_RS10965	COG3706	GGDEF domain
C2I06_RS10970	COG0285	dihydrofolate synthase activity
C2I06_RS10975	COG0525	valine-tRNA ligase activity
C2I06_RS10985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2I06_RS10990	COG1388	LysM domain
C2I06_RS10990	COG1388	LysM domain
C2I06_RS10995	COG0726	polysaccharide deacetylase
C2I06_RS10995	COG1649	PFAM Uncharacterised BCR, COG1649
C2I06_RS11005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2I06_RS11015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C2I06_RS11020	COG0113	porphobilinogen synthase activity
C2I06_RS11030	COG0181	hydroxymethylbilane synthase activity
C2I06_RS11035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C2I06_RS11050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C2I06_RS11055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C2I06_RS11060	COG1067	ATP-dependent peptidase activity
C2I06_RS11060	COG0470	DNA polymerase III
C2I06_RS11070	COG0544	peptidyl-prolyl cis-trans isomerase activity
C2I06_RS11080	COG0066	3-isopropylmalate dehydratase activity
C2I06_RS11085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C2I06_RS11090	COG0473	3-isopropylmalate dehydrogenase activity
C2I06_RS11095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C2I06_RS11100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C2I06_RS11105	COG0440	acetolactate synthase activity
C2I06_RS11110	COG0028	Belongs to the TPP enzyme family
C2I06_RS11120	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C2I06_RS11135	COG0622	Phosphoesterase
C2I06_RS11150	COG5401	PFAM Sporulation and spore germination
C2I06_RS11155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C2I06_RS11160	COG1846	Transcriptional regulator
C2I06_RS11165	COG2197	response regulator
C2I06_RS11175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C2I06_RS11180	COG1053	succinate dehydrogenase
C2I06_RS11185	COG2009	succinate dehydrogenase
C2I06_RS11190	COG1719	4-vinyl reductase, 4VR
C2I06_RS11205	COG3118	belongs to the thioredoxin family
C2I06_RS11210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C2I06_RS11215	COG2086	electron transfer activity
C2I06_RS11220	COG0318	PFAM AMP-dependent synthetase and ligase
C2I06_RS11225	COG3766	membrane
C2I06_RS11230	COG1193	negative regulation of DNA recombination
C2I06_RS11235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C2I06_RS11235	COG1796	DNA polymerase
C2I06_RS11245	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C2I06_RS11250	COG1940	carbohydrate kinase activity
C2I06_RS11260	COG0395	ABC-type sugar transport system, permease component
C2I06_RS11265	COG1175	transmembrane transport
C2I06_RS11275	COG0072	phenylalanine-tRNA ligase activity
C2I06_RS11275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C2I06_RS11280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C2I06_RS11285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2I06_RS11295	COG1070	Carbohydrate kinase
C2I06_RS11300	COG2115	Belongs to the xylose isomerase family
C2I06_RS11305	COG1940	carbohydrate kinase activity
C2I06_RS11310	COG0628	permease
C2I06_RS11315	COG1363	Peptidase, m42
C2I06_RS11330	COG3326	Membrane
C2I06_RS11335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C2I06_RS11345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C2I06_RS11350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C2I06_RS11365	COG1484	DNA-dependent DNA replication
C2I06_RS11370	COG3611	Membrane attachment protein
C2I06_RS11375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C2I06_RS11385	COG1971	Probably functions as a manganese efflux pump
C2I06_RS11390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C2I06_RS11400	COG5002	protein histidine kinase activity
C2I06_RS11405	COG0745	RESPONSE REGULATOR receiver
C2I06_RS11415	COG0538	isocitrate dehydrogenase activity
C2I06_RS11420	COG0372	Belongs to the citrate synthase family
C2I06_RS11425	COG2707	UPF0756 membrane protein
C2I06_RS11430	COG0628	permease
C2I06_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS11480	COG0395	ABC-type sugar transport system, permease component
C2I06_RS11485	COG4209	transmembrane transport
C2I06_RS11490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C2I06_RS11495	COG5578	integral membrane protein
C2I06_RS11500	COG0395	ABC-type sugar transport system, permease component
C2I06_RS11505	COG1175	transmembrane transport
C2I06_RS11510	COG1653	transport
C2I06_RS11515	COG2207	Transcriptional regulator
C2I06_RS11520	COG2972	Histidine kinase
C2I06_RS11525	COG3030	protein affecting phage T7 exclusion by the F plasmid
C2I06_RS11540	COG0825	malonyl-CoA metabolic process
C2I06_RS11545	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C2I06_RS11550	COG2186	Transcriptional regulator
C2I06_RS11555	COG0587	DNA-directed DNA polymerase activity
C2I06_RS11570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C2I06_RS11575	COG4109	DRTGG domain
C2I06_RS11585	COG0006	proline dipeptidase activity
C2I06_RS11595	COG0589	response to stress
C2I06_RS11600	COG0165	Argininosuccinate lyase
C2I06_RS11605	COG0137	argininosuccinate synthase activity
C2I06_RS11610	COG0521	Mo-molybdopterin cofactor biosynthetic process
C2I06_RS11615	COG3973	AAA domain
C2I06_RS11635	COG0827	DNA restriction-modification system
C2I06_RS11640	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C2I06_RS11645	COG3874	Sporulation protein YtfJ
C2I06_RS11655	COG1714	RDD family
C2I06_RS11660	COG0616	signal peptide processing
C2I06_RS11665	COG2962	Rard protein
C2I06_RS11670	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C2I06_RS11675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2I06_RS11685	COG0301	tRNA thio-modification
C2I06_RS11690	COG1104	cysteine desulfurase activity
C2I06_RS11695	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C2I06_RS11700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C2I06_RS11705	COG1309	transcriptional regulator
C2I06_RS11710	COG1956	GAF domain-containing protein
C2I06_RS11715	COG2203	Gaf domain
C2I06_RS11715	COG2199	diguanylate cyclase activity
C2I06_RS11720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C2I06_RS11745	COG1605	Chorismate mutase
C2I06_RS11745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C2I06_RS11750	COG0849	cell division
C2I06_RS11755	COG3118	belongs to the thioredoxin family
C2I06_RS11760	COG4980	gas vesicle protein
C2I06_RS11765	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C2I06_RS11770	COG2309	aminopeptidase activity
C2I06_RS11775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C2I06_RS11780	COG1674	ftsk spoiiie
C2I06_RS11785	COG4848	Belongs to the UPF0354 family
C2I06_RS11790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2I06_RS11795	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C2I06_RS11800	COG1363	Peptidase, m42
C2I06_RS11805	COG5584	Small secreted protein
C2I06_RS11810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C2I06_RS11820	COG0510	thiamine kinase activity
C2I06_RS11825	COG1523	belongs to the glycosyl hydrolase 13 family
C2I06_RS11835	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C2I06_RS11845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2I06_RS11855	COG1349	DNA-binding transcription factor activity
C2I06_RS11860	COG1187	pseudouridine synthase activity
C2I06_RS11865	COG2244	polysaccharide biosynthetic process
C2I06_RS11870	COG2081	HI0933 family
C2I06_RS11880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C2I06_RS11885	COG0495	leucyl-tRNA aminoacylation
C2I06_RS11895	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
C2I06_RS11900	COG0154	amidase activity
C2I06_RS11905	COG0406	alpha-ribazole phosphatase activity
C2I06_RS11910	COG2814	Major facilitator Superfamily
C2I06_RS11925	COG1242	4 iron, 4 sulfur cluster binding
C2I06_RS11930	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C2I06_RS11940	COG2267	carboxylic ester hydrolase activity
C2I06_RS11945	COG4990	cell redox homeostasis
C2I06_RS11950	COG0367	asparagine synthase
C2I06_RS11955	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C2I06_RS11965	COG1506	peptidase
C2I06_RS11970	COG0494	nUDIX hydrolase
C2I06_RS11985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2I06_RS11995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C2I06_RS12000	COG0288	reversible hydration of carbon dioxide
C2I06_RS12020	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C2I06_RS12025	COG0596	Alpha beta hydrolase
C2I06_RS12035	COG1169	isochorismate synthase
C2I06_RS12040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C2I06_RS12045	COG0058	SHG alpha-glucan phosphorylase activity
C2I06_RS12050	COG0297	glycogen (starch) synthase activity
C2I06_RS12055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C2I06_RS12060	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C2I06_RS12195	COG1285	pathogenesis
C2I06_RS12215	COG5002	protein histidine kinase activity
C2I06_RS12235	COG0604	alcohol dehydrogenase
C2I06_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS12245	COG0778	Nitroreductase
C2I06_RS12255	COG3729	General stress protein
C2I06_RS12275	COG2059	Chromate
C2I06_RS12280	COG2059	Chromate
C2I06_RS12290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2I06_RS12290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C2I06_RS12300	COG1309	transcriptional regulator
C2I06_RS12305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C2I06_RS12325	COG1979	alcohol dehydrogenase
C2I06_RS12330	COG2155	Conserved Protein
C2I06_RS12335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C2I06_RS12340	COG1098	S1 RNA binding domain
C2I06_RS12345	COG0436	Aminotransferase
C2I06_RS12350	COG1522	sequence-specific DNA binding
C2I06_RS12360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2I06_RS12365	COG2011	ABC-type metal ion transport system permease component
C2I06_RS12370	COG1464	Belongs to the NlpA lipoprotein family
C2I06_RS12380	COG1914	H( )-stimulated, divalent metal cation uptake system
C2I06_RS12385	COG2032	superoxide dismutase activity
C2I06_RS12395	COG5018	Exonuclease
C2I06_RS12405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C2I06_RS12405	COG2111	Na H antiporter
C2I06_RS12410	COG2111	Na H antiporter
C2I06_RS12415	COG1006	Multisubunit Na H antiporter MnhC subunit
C2I06_RS12420	COG0651	ATP synthesis coupled electron transport
C2I06_RS12425	COG1863	multisubunit Na H antiporter MnhE subunit
C2I06_RS12430	COG2212	antiporter activity
C2I06_RS12435	COG1320	monovalent cation:proton antiporter activity
C2I06_RS12455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C2I06_RS12485	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS12495	COG3243	poly(R)-hydroxyalkanoic acid synthase
C2I06_RS12500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C2I06_RS12505	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C2I06_RS12510	COG3584	3D domain protein
C2I06_RS12515	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS12545	COG1476	TRANSCRIPTIONal
C2I06_RS12600	COG0316	Belongs to the HesB IscA family
C2I06_RS12610	COG4844	belongs to the
C2I06_RS12615	COG1252	NADH dehydrogenase
C2I06_RS12620	COG4837	Protein of unknown function (DUF1462)
C2I06_RS12625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C2I06_RS12630	COG0083	homoserine kinase activity
C2I06_RS12635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C2I06_RS12640	COG0460	homoserine dehydrogenase
C2I06_RS12645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C2I06_RS12650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C2I06_RS12655	COG0647	UMP catabolic process
C2I06_RS12660	COG2445	Protein of unknown function DUF86
C2I06_RS12665	COG2200	EAL domain
C2I06_RS12665	COG3287	FIST C domain
C2I06_RS12665	COG2199	diguanylate cyclase activity
C2I06_RS12670	COG4470	Protein conserved in bacteria
C2I06_RS12675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C2I06_RS12690	COG3377	Domain of unknown function (DUF1805)
C2I06_RS12695	COG0737	Belongs to the 5'-nucleotidase family
C2I06_RS12700	COG1801	Protein of unknown function DUF72
C2I06_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS12710	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C2I06_RS12725	COG1414	Transcriptional regulator
C2I06_RS12730	COG0561	phosphatase activity
C2I06_RS12735	COG0110	maltose O-acetyltransferase activity
C2I06_RS12740	COG0346	lactoylglutathione lyase activity
C2I06_RS12750	COG1940	carbohydrate kinase activity
C2I06_RS12755	COG0719	Fe-S assembly protein
C2I06_RS12760	COG0822	iron-sulfur transferase activity
C2I06_RS12765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C2I06_RS12770	COG0719	Fe-S assembly protein
C2I06_RS12775	COG0396	ATPase activity
C2I06_RS12780	COG1464	Belongs to the NlpA lipoprotein family
C2I06_RS12785	COG2011	ABC-type metal ion transport system permease component
C2I06_RS12790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2I06_RS12800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2I06_RS12805	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C2I06_RS12810	COG0509	glycine decarboxylation via glycine cleavage system
C2I06_RS12815	COG1393	Belongs to the ArsC family
C2I06_RS12820	COG1960	acyl-CoA dehydrogenase activity
C2I06_RS12825	COG1250	3-hydroxyacyl-CoA dehydrogenase
C2I06_RS12825	COG1024	Enoyl-CoA hydratase
C2I06_RS12840	COG5577	PFAM Coat F domain
C2I06_RS12850	COG0772	Belongs to the SEDS family
C2I06_RS12855	COG0840	transmembrane signaling receptor activity
C2I06_RS12860	COG1126	abc transporter atp-binding protein
C2I06_RS12865	COG0765	amino acid transport
C2I06_RS12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS12885	COG1132	(ABC) transporter
C2I06_RS12890	COG1132	(ABC) transporter
C2I06_RS12895	COG3118	belongs to the thioredoxin family
C2I06_RS12900	COG0544	peptidyl-prolyl cis-trans isomerase activity
C2I06_RS12920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C2I06_RS12940	COG1968	undecaprenyl-diphosphatase activity
C2I06_RS12945	COG0628	permease
C2I06_RS12950	COG2409	Drug exporters of the RND superfamily
C2I06_RS12950	COG1033	growth of symbiont in host cell
C2I06_RS12955	COG1846	Transcriptional regulator
C2I06_RS12960	COG2050	protein possibly involved in aromatic compounds catabolism
C2I06_RS12970	COG0366	Alpha amylase catalytic
C2I06_RS12975	COG1609	Transcriptional regulator
C2I06_RS12980	COG1733	regulation of RNA biosynthetic process
C2I06_RS12985	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C2I06_RS12990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C2I06_RS13000	COG3764	Sortase (surface protein transpeptidase)
C2I06_RS13005	COG1283	sodium-dependent phosphate transmembrane transporter activity
C2I06_RS13015	COG0488	(ABC) transporter
C2I06_RS13020	COG1609	Transcriptional regulator
C2I06_RS13025	COG0673	inositol 2-dehydrogenase activity
C2I06_RS13030	COG1874	Beta-galactosidase
C2I06_RS13035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2I06_RS13040	COG0395	ABC-type sugar transport system, permease component
C2I06_RS13045	COG1175	transmembrane transport
C2I06_RS13050	COG1653	transport
C2I06_RS13055	COG4753	response regulator
C2I06_RS13055	COG2207	Transcriptional regulator
C2I06_RS13060	COG2972	Histidine kinase
C2I06_RS13065	COG5578	integral membrane protein
C2I06_RS13075	COG5577	PFAM Coat F domain
C2I06_RS13080	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS13095	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS13100	COG0710	3-dehydroquinate dehydratase activity
C2I06_RS13105	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C2I06_RS13110	COG0753	catalase activity
C2I06_RS13120	COG0656	L-ascorbic acid biosynthetic process
C2I06_RS13125	COG0395	ABC-type sugar transport system, permease component
C2I06_RS13130	COG1175	transmembrane transport
C2I06_RS13135	COG1653	transport
C2I06_RS13140	COG1486	melibiose metabolic process
C2I06_RS13145	COG2207	Transcriptional regulator
C2I06_RS13155	COG2217	Heavy metal translocating P-type atpase
C2I06_RS13160	COG2608	mercury ion transmembrane transporter activity
C2I06_RS13170	COG1802	Transcriptional regulator
C2I06_RS13180	COG2814	Major facilitator Superfamily
C2I06_RS13185	COG0789	Transcriptional regulator
C2I06_RS13190	COG2188	Transcriptional regulator
C2I06_RS13195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C2I06_RS13210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS13230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS13235	COG0765	amino acid transport
C2I06_RS13240	COG1126	abc transporter atp-binding protein
C2I06_RS13255	COG0395	ABC-type sugar transport system, permease component
C2I06_RS13260	COG1175	transmembrane transport
C2I06_RS13265	COG1653	transport
C2I06_RS13275	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS13285	COG1063	alcohol dehydrogenase
C2I06_RS13290	COG3775	system Galactitol-specific IIC component
C2I06_RS13305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS13305	COG3711	transcriptional antiterminator
C2I06_RS13315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C2I06_RS13320	COG0557	exoribonuclease II activity
C2I06_RS13325	COG1647	Serine aminopeptidase, S33
C2I06_RS13330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2I06_RS13345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C2I06_RS13385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS13395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C2I06_RS13400	COG1660	Displays ATPase and GTPase activities
C2I06_RS13405	COG1051	belongs to the nudix hydrolase family
C2I06_RS13420	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS13430	COG0457	Tetratricopeptide repeat
C2I06_RS13435	COG0140	phosphoribosyl-ATP diphosphatase activity
C2I06_RS13435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C2I06_RS13440	COG0107	imidazoleglycerol-phosphate synthase activity
C2I06_RS13445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C2I06_RS13450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C2I06_RS13455	COG0131	Imidazoleglycerol-phosphate dehydratase
C2I06_RS13460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C2I06_RS13465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C2I06_RS13470	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C2I06_RS13475	COG0110	maltose O-acetyltransferase activity
C2I06_RS13480	COG0546	phosphoglycolate phosphatase activity
C2I06_RS13495	COG1950	PFAM Membrane protein of
C2I06_RS13500	COG3595	metallopeptidase activity
C2I06_RS13505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C2I06_RS13510	COG0556	nucleotide-excision repair
C2I06_RS13515	COG4897	Protein conserved in bacteria
C2I06_RS13520	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS13535	COG1454	alcohol dehydrogenase
C2I06_RS13535	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS13550	COG1595	DNA-templated transcription, initiation
C2I06_RS13560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C2I06_RS13570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C2I06_RS13575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C2I06_RS13580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2I06_RS13585	COG2508	Transcriptional regulator
C2I06_RS13590	COG2233	PERMEase
C2I06_RS13595	COG0281	malic enzyme
C2I06_RS13600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C2I06_RS13620	COG1053	succinate dehydrogenase
C2I06_RS13625	COG2030	dehydratase
C2I06_RS13630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C2I06_RS13635	COG4988	ABC transporter
C2I06_RS13640	COG1294	oxidase, subunit
C2I06_RS13645	COG1271	oxidase subunit
C2I06_RS13650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2I06_RS13655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2I06_RS13660	COG0205	6-phosphofructokinase activity
C2I06_RS13665	COG0698	ribose 5-phosphate isomerase
C2I06_RS13675	COG1063	alcohol dehydrogenase
C2I06_RS13680	COG3775	system Galactitol-specific IIC component
C2I06_RS13685	COG3414	Phosphotransferase system galactitol-specific IIB component
C2I06_RS13690	COG3414	Phosphotransferase system galactitol-specific IIB component
C2I06_RS13705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C2I06_RS13710	COG0205	6-phosphofructokinase activity
C2I06_RS13715	COG0698	ribose 5-phosphate isomerase
C2I06_RS13725	COG0656	L-ascorbic acid biosynthetic process
C2I06_RS13730	COG2814	Major facilitator Superfamily
C2I06_RS13735	COG1733	regulation of RNA biosynthetic process
C2I06_RS13740	COG0793	Belongs to the peptidase S41A family
C2I06_RS13740	COG3409	Peptidoglycan-binding domain 1 protein
C2I06_RS13745	COG3546	catalase activity
C2I06_RS13750	COG2217	Heavy metal translocating P-type atpase
C2I06_RS13755	COG0640	Transcriptional regulator
C2I06_RS13765	COG2177	Part of the ABC transporter FtsEX involved in
C2I06_RS13770	COG2884	Cell division ATP-binding protein ftsE
C2I06_RS13775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS13795	COG0463	Glycosyl transferase, family 2
C2I06_RS13805	COG0653	protein targeting
C2I06_RS13830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C2I06_RS13835	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2I06_RS13840	COG3842	ATPase activity
C2I06_RS13855	COG1802	Transcriptional regulator
C2I06_RS13860	COG2059	Chromate
C2I06_RS13865	COG2059	Chromate
C2I06_RS13870	COG0405	Gamma-glutamyltransferase
C2I06_RS13885	COG1522	sequence-specific DNA binding
C2I06_RS13895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C2I06_RS13905	COG1516	flagellar protein fliS
C2I06_RS13910	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C2I06_RS13920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C2I06_RS13925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C2I06_RS13930	COG2089	acid synthase
C2I06_RS13940	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C2I06_RS13960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C2I06_RS13965	COG1215	transferase activity, transferring glycosyl groups
C2I06_RS13985	COG1086	Polysaccharide biosynthesis protein
C2I06_RS14000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C2I06_RS14005	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C2I06_RS14010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C2I06_RS14015	COG1256	bacterial-type flagellum assembly
C2I06_RS14015	COG4786	Flagellar basal body rod
C2I06_RS14030	COG1728	Protein conserved in bacteria
C2I06_RS14040	COG1516	flagellar protein fliS
C2I06_RS14060	COG1040	competence protein
C2I06_RS14065	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C2I06_RS14075	COG1307	EDD domain protein, DegV family
C2I06_RS14080	COG2197	response regulator
C2I06_RS14085	COG4585	Histidine kinase
C2I06_RS14090	COG1739	Uncharacterized protein family UPF0029
C2I06_RS14095	COG1316	TRANSCRIPTIONal
C2I06_RS14100	COG2247	cell wall binding repeat
C2I06_RS14100	COG2385	sporulation resulting in formation of a cellular spore
C2I06_RS14105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C2I06_RS14110	COG1442	glycosyl transferase family 8
C2I06_RS14110	COG1216	Glycosyl transferase, family 2
C2I06_RS14115	COG1134	teichoic acid transport
C2I06_RS14120	COG1682	transport, permease protein
C2I06_RS14125	COG4193	domain, Protein
C2I06_RS14130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2I06_RS14135	COG1316	TRANSCRIPTIONal
C2I06_RS14140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C2I06_RS14145	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C2I06_RS14155	COG0346	lactoylglutathione lyase activity
C2I06_RS14160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C2I06_RS14165	COG0366	Alpha amylase catalytic
C2I06_RS14170	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C2I06_RS14180	COG0629	single-stranded DNA binding
C2I06_RS14185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C2I06_RS14195	COG0840	transmembrane signaling receptor activity
C2I06_RS14200	COG2814	Major facilitator Superfamily
C2I06_RS14205	COG1335	isochorismatase
C2I06_RS14210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2I06_RS14215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2I06_RS14230	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS14250	COG0604	alcohol dehydrogenase
C2I06_RS14255	COG1660	Displays ATPase and GTPase activities
C2I06_RS14260	COG0371	Dehydrogenase
C2I06_RS14265	COG2084	Dehydrogenase
C2I06_RS14270	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
C2I06_RS14275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2I06_RS14280	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C2I06_RS14295	COG3339	Conserved Protein
C2I06_RS14300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C2I06_RS14315	COG2011	ABC-type metal ion transport system permease component
C2I06_RS14320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2I06_RS14330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C2I06_RS14335	COG0840	transmembrane signaling receptor activity
C2I06_RS14340	COG0745	RESPONSE REGULATOR receiver
C2I06_RS14345	COG0642	Histidine kinase
C2I06_RS14350	COG1136	(ABC) transporter
C2I06_RS14355	COG0577	efflux transmembrane transporter activity
C2I06_RS14365	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C2I06_RS14370	COG4191	Histidine kinase
C2I06_RS14395	COG1737	Transcriptional regulator
C2I06_RS14400	COG1486	melibiose metabolic process
C2I06_RS14405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS14405	COG1263	PTS System
C2I06_RS14410	COG0300	oxidoreductase activity
C2I06_RS14415	COG0656	L-ascorbic acid biosynthetic process
C2I06_RS14425	COG0778	Nitroreductase
C2I06_RS14430	COG1115	amino acid carrier protein
C2I06_RS14440	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C2I06_RS14450	COG0561	phosphatase activity
C2I06_RS14480	COG1164	Oligoendopeptidase f
C2I06_RS14485	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS14490	COG2188	Transcriptional regulator
C2I06_RS14500	COG0840	transmembrane signaling receptor activity
C2I06_RS14500	COG5278	phosphoserine phosphatase activity
C2I06_RS14515	COG1695	Transcriptional regulator
C2I06_RS14530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2I06_RS14530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2I06_RS14535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C2I06_RS14570	COG2124	cytochrome p450
C2I06_RS14575	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS14580	COG2814	Major facilitator Superfamily
C2I06_RS14585	COG0383	alpha-mannosidase activity
C2I06_RS14605	COG2207	Transcriptional regulator
C2I06_RS14605	COG4753	response regulator
C2I06_RS14610	COG2972	Histidine kinase
C2I06_RS14620	COG1653	transport
C2I06_RS14625	COG0395	ABC-type sugar transport system, permease component
C2I06_RS14630	COG1175	transmembrane transport
C2I06_RS14635	COG2207	Transcriptional regulator
C2I06_RS14645	COG0477	Major facilitator Superfamily
C2I06_RS14650	COG1309	transcriptional regulator
C2I06_RS14655	COG0778	Nitroreductase
C2I06_RS14660	COG2207	Transcriptional regulator
C2I06_RS14660	COG4753	response regulator
C2I06_RS14665	COG2972	Histidine kinase
C2I06_RS14680	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C2I06_RS14685	COG0395	ABC-type sugar transport system, permease component
C2I06_RS14690	COG4209	transmembrane transport
C2I06_RS14700	COG2188	Transcriptional regulator
C2I06_RS14705	COG4948	Mandelate Racemase Muconate Lactonizing
C2I06_RS14710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS14710	COG2190	(PTS) system
C2I06_RS14710	COG1263	PTS System
C2I06_RS14715	COG1525	nuclease
C2I06_RS14720	COG1178	ABC-type Fe3 transport system permease component
C2I06_RS14725	COG3842	ATPase activity
C2I06_RS14730	COG1840	ABC-type Fe3 transport system, periplasmic component
C2I06_RS14735	COG2207	Transcriptional regulator
C2I06_RS14735	COG4753	response regulator
C2I06_RS14745	COG1263	PTS System
C2I06_RS14745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS14760	COG3835	regulator
C2I06_RS14765	COG1929	Belongs to the glycerate kinase type-1 family
C2I06_RS14770	COG2610	gluconate transmembrane transporter activity
C2I06_RS14790	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2I06_RS14795	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2I06_RS14800	COG3842	ATPase activity
C2I06_RS14805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C2I06_RS14815	COG1988	membrane-bound metal-dependent
C2I06_RS14835	COG3345	alpha-galactosidase
C2I06_RS14845	COG0395	ABC-type sugar transport system, permease component
C2I06_RS14850	COG1175	transmembrane transport
C2I06_RS14885	COG3250	beta-galactosidase activity
C2I06_RS14890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2I06_RS14895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS14900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS14905	COG2197	response regulator
C2I06_RS14910	COG2200	EAL domain
C2I06_RS14910	COG2199	diguanylate cyclase activity
C2I06_RS14915	COG3279	Response regulator of the LytR AlgR family
C2I06_RS14925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C2I06_RS14970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS14975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2I06_RS14985	COG1316	TRANSCRIPTIONal
C2I06_RS14990	COG2340	Cysteine-rich secretory protein family
C2I06_RS15020	COG2153	protein acetylation
C2I06_RS15035	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2I06_RS15045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS15055	COG2188	Transcriptional regulator
C2I06_RS15060	COG2368	4-hydroxyphenylacetate
C2I06_RS15090	COG0395	ABC-type sugar transport system, permease component
C2I06_RS15095	COG1175	transmembrane transport
C2I06_RS15105	COG1940	carbohydrate kinase activity
C2I06_RS15110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C2I06_RS15130	COG2720	vancomycin resistance protein
C2I06_RS15135	COG0346	lactoylglutathione lyase activity
C2I06_RS15150	COG1609	Transcriptional regulator
C2I06_RS15165	COG2160	L-arabinose isomerase activity
C2I06_RS15200	COG2079	MmgE PrpD family protein
C2I06_RS15205	COG1473	amidohydrolase
C2I06_RS15210	COG1126	abc transporter atp-binding protein
C2I06_RS15215	COG0765	amino acid transport
C2I06_RS15220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS15230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS15235	COG0436	Aminotransferase
C2I06_RS15240	COG0371	Dehydrogenase
C2I06_RS15255	COG4895	conserved protein (DUF2196)
C2I06_RS15275	COG1846	Transcriptional regulator
C2I06_RS15285	COG2814	Major facilitator Superfamily
C2I06_RS15290	COG0395	ABC-type sugar transport system, permease component
C2I06_RS15295	COG1175	transmembrane transport
C2I06_RS15305	COG0165	Argininosuccinate lyase
C2I06_RS15320	COG0840	transmembrane signaling receptor activity
C2I06_RS15330	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS15335	COG2188	Transcriptional regulator
C2I06_RS15340	COG2222	sugar isomerase
C2I06_RS15345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS15350	COG1082	Xylose isomerase domain protein TIM barrel
C2I06_RS15355	COG1126	abc transporter atp-binding protein
C2I06_RS15360	COG0765	amino acid transport
C2I06_RS15375	COG0395	ABC-type sugar transport system, permease component
C2I06_RS15380	COG4209	transmembrane transport
C2I06_RS15390	COG3279	Response regulator of the LytR AlgR family
C2I06_RS15395	COG2972	Histidine kinase
C2I06_RS15400	COG0800	Aldolase
C2I06_RS15405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2I06_RS15415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C2I06_RS15420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS15420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS15440	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C2I06_RS15480	COG1131	(ABC) transporter
C2I06_RS15485	COG2205	protein histidine kinase activity
C2I06_RS15490	COG0745	RESPONSE REGULATOR receiver
C2I06_RS15495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C2I06_RS15505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C2I06_RS15510	COG3716	PTS system mannose fructose sorbose family IID component
C2I06_RS15515	COG3715	PTS system
C2I06_RS15525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS15525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS15530	COG1846	Transcriptional regulator
C2I06_RS15530	COG1940	carbohydrate kinase activity
C2I06_RS15545	COG4821	SIS domain
C2I06_RS15555	COG1402	creatininase
C2I06_RS15575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS15580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS15590	COG1141	Ferredoxin
C2I06_RS15595	COG0402	S-adenosylhomocysteine deaminase activity
C2I06_RS15600	COG0402	S-adenosylhomocysteine deaminase activity
C2I06_RS15615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2I06_RS15635	COG2271	Major facilitator Superfamily
C2I06_RS15640	COG4948	Mandelate Racemase Muconate Lactonizing
C2I06_RS15645	COG0800	Aldolase
C2I06_RS15650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS15655	COG1414	Transcriptional regulator
C2I06_RS15670	COG1522	sequence-specific DNA binding
C2I06_RS15675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS15675	COG2190	(PTS) system
C2I06_RS15675	COG1263	PTS System
C2I06_RS15680	COG3711	transcriptional antiterminator
C2I06_RS15690	COG1609	Transcriptional regulator
C2I06_RS15695	COG1694	Mazg nucleotide pyrophosphohydrolase
C2I06_RS15700	COG3420	alginic acid biosynthetic process
C2I06_RS15705	COG1737	Transcriptional regulator
C2I06_RS15725	COG2081	HI0933 family
C2I06_RS15735	COG1522	sequence-specific DNA binding
C2I06_RS15750	COG3716	PTS system mannose fructose sorbose family IID component
C2I06_RS15755	COG3716	PTS system mannose fructose sorbose family IID component
C2I06_RS15765	COG1940	carbohydrate kinase activity
C2I06_RS15770	COG2188	Transcriptional regulator
C2I06_RS15780	COG4821	SIS domain
C2I06_RS15790	COG1609	Transcriptional regulator
C2I06_RS15805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C2I06_RS15820	COG3764	Sortase (surface protein transpeptidase)
C2I06_RS15850	COG0543	2 iron, 2 sulfur cluster binding
C2I06_RS15855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C2I06_RS15865	COG2814	Major facilitator Superfamily
C2I06_RS15875	COG0679	Auxin Efflux Carrier
C2I06_RS15880	COG0281	malic enzyme
C2I06_RS15910	COG0402	S-adenosylhomocysteine deaminase activity
C2I06_RS15920	COG2190	(PTS) system
C2I06_RS15920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS15920	COG1263	PTS System
C2I06_RS15925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS15930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C2I06_RS15935	COG1609	Transcriptional regulator
C2I06_RS15955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C2I06_RS15970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS15985	COG1216	Glycosyl transferase, family 2
C2I06_RS16010	COG1216	Glycosyl transferase, family 2
C2I06_RS16030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C2I06_RS16035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C2I06_RS16040	COG4464	protein tyrosine phosphatase activity
C2I06_RS16045	COG0489	protein tyrosine kinase activity
C2I06_RS16050	COG3944	biosynthesis protein
C2I06_RS16060	COG1396	sequence-specific DNA binding
C2I06_RS16085	COG0662	Cupin 2, conserved barrel domain protein
C2I06_RS16085	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C2I06_RS16090	COG1132	(ABC) transporter
C2I06_RS16110	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS16120	COG5039	Polysaccharide pyruvyl transferase
C2I06_RS16140	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS16155	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS16160	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS16170	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS16175	COG1215	transferase activity, transferring glycosyl groups
C2I06_RS16180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C2I06_RS16185	COG0489	protein tyrosine kinase activity
C2I06_RS16190	COG3944	biosynthesis protein
C2I06_RS16195	COG0668	transmembrane transport
C2I06_RS16205	COG5578	integral membrane protein
C2I06_RS16215	COG0395	ABC-type sugar transport system, permease component
C2I06_RS16220	COG4209	transmembrane transport
C2I06_RS16225	COG1486	melibiose metabolic process
C2I06_RS16240	COG2755	lipolytic protein G-D-S-L family
C2I06_RS16240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C2I06_RS16245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C2I06_RS16245	COG2755	lipolytic protein G-D-S-L family
C2I06_RS16255	COG5002	protein histidine kinase activity
C2I06_RS16260	COG0745	RESPONSE REGULATOR receiver
C2I06_RS16265	COG2814	Major facilitator Superfamily
C2I06_RS16270	COG4978	Transcriptional regulator
C2I06_RS16270	COG0789	Transcriptional regulator
C2I06_RS16275	COG1846	Transcriptional regulator
C2I06_RS16280	COG1132	(ABC) transporter
C2I06_RS16305	COG3119	arylsulfatase activity
C2I06_RS16310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS16310	COG2190	(PTS) system
C2I06_RS16310	COG1263	PTS System
C2I06_RS16315	COG3711	transcriptional antiterminator
C2I06_RS16320	COG2190	(PTS) system
C2I06_RS16325	COG3711	transcriptional antiterminator
C2I06_RS16325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS16335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS16340	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2I06_RS16345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS16360	COG2002	toxin-antitoxin pair type II binding
C2I06_RS16365	COG3706	GGDEF domain
C2I06_RS16370	COG1742	UPF0060 membrane protein
C2I06_RS16385	COG2199	diguanylate cyclase activity
C2I06_RS16385	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C2I06_RS16390	COG1846	Transcriptional regulator
C2I06_RS16395	COG1566	PFAM secretion protein HlyD family protein
C2I06_RS16400	COG2814	Major facilitator Superfamily
C2I06_RS16410	COG0673	inositol 2-dehydrogenase activity
C2I06_RS16420	COG2814	Major facilitator Superfamily
C2I06_RS16425	COG0596	Alpha beta hydrolase
C2I06_RS16430	COG1309	transcriptional regulator
C2I06_RS16440	COG0667	Aldo Keto reductase
C2I06_RS16445	COG1940	carbohydrate kinase activity
C2I06_RS16450	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS16455	COG3458	cephalosporin-C deacetylase activity
C2I06_RS16460	COG1609	Transcriptional regulator
C2I06_RS16465	COG0701	Predicted permease
C2I06_RS16470	COG0709	Synthesizes selenophosphate from selenide and ATP
C2I06_RS16485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C2I06_RS16490	COG1388	LysM domain
C2I06_RS16495	COG4191	Histidine kinase
C2I06_RS16500	COG0025	NhaP-type Na H and K H
C2I06_RS16530	COG1408	metallophosphoesterase
C2I06_RS16540	COG2197	response regulator
C2I06_RS16545	COG4585	Histidine kinase
C2I06_RS16550	COG0842	Transport permease protein
C2I06_RS16555	COG1131	(ABC) transporter
C2I06_RS16580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C2I06_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS16590	COG0697	spore germination
C2I06_RS16595	COG1388	LysM domain
C2I06_RS16595	COG0791	NLP P60 protein
C2I06_RS16600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C2I06_RS16605	COG5522	Integral membrane protein (intg_mem_TP0381)
C2I06_RS16615	COG0460	homoserine dehydrogenase
C2I06_RS16630	COG2719	SpoVR family
C2I06_RS16635	COG0768	penicillin binding
C2I06_RS16640	COG3011	Protein conserved in bacteria
C2I06_RS16650	COG1388	LysM domain
C2I06_RS16650	COG0791	NLP P60 protein
C2I06_RS16660	COG4715	Zinc finger, swim domain protein
C2I06_RS16665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C2I06_RS16695	COG4786	Flagellar basal body rod
C2I06_RS16700	COG4786	Flagellar basal body rod
C2I06_RS16705	COG1077	Cell shape determining protein MreB Mrl
C2I06_RS16710	COG1609	Transcriptional regulator
C2I06_RS16715	COG0739	heme binding
C2I06_RS16725	COG2385	sporulation resulting in formation of a cellular spore
C2I06_RS16730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C2I06_RS16740	COG4836	Membrane
C2I06_RS16745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C2I06_RS16750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C2I06_RS16755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C2I06_RS16765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C2I06_RS16770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C2I06_RS16775	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C2I06_RS16780	COG0356	it plays a direct role in the translocation of protons across the membrane
C2I06_RS16790	COG1404	Belongs to the peptidase S8 family
C2I06_RS16795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C2I06_RS16800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C2I06_RS16810	COG0840	transmembrane signaling receptor activity
C2I06_RS16820	COG1971	Probably functions as a manganese efflux pump
C2I06_RS16825	COG0009	L-threonylcarbamoyladenylate synthase
C2I06_RS16840	COG1012	belongs to the aldehyde dehydrogenase family
C2I06_RS16845	COG0506	proline dehydrogenase activity
C2I06_RS16850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2I06_RS16855	COG1321	iron dependent repressor
C2I06_RS16855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C2I06_RS16860	COG1121	(ABC) transporter
C2I06_RS16865	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2I06_RS16880	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C2I06_RS16885	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS16890	COG1253	flavin adenine dinucleotide binding
C2I06_RS16895	COG1253	flavin adenine dinucleotide binding
C2I06_RS16905	COG1435	thymidine kinase activity
C2I06_RS16915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C2I06_RS16925	COG0191	fructose-bisphosphate aldolase activity
C2I06_RS16930	COG2204	response regulator
C2I06_RS16935	COG4821	SIS domain
C2I06_RS16940	COG0504	CTP synthase activity
C2I06_RS16945	COG3343	RNA polymerase activity
C2I06_RS16955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2I06_RS16965	COG3279	Response regulator of the LytR AlgR family
C2I06_RS16970	COG4555	ABC transporter
C2I06_RS16975	COG1668	transmembrane transport
C2I06_RS16990	COG1131	(ABC) transporter
C2I06_RS17015	COG0018	arginyl-trna synthetase
C2I06_RS17020	COG4506	Protein conserved in bacteria
C2I06_RS17025	COG0791	NLP P60 protein
C2I06_RS17025	COG3103	Sh3 type 3 domain protein
C2I06_RS17025	COG1388	LysM domain
C2I06_RS17030	COG0010	Belongs to the arginase family
C2I06_RS17035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C2I06_RS17040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2I06_RS17055	COG1193	negative regulation of DNA recombination
C2I06_RS17065	COG1994	Peptidase M50
C2I06_RS17070	COG1942	4-Oxalocrotonate Tautomerase
C2I06_RS17075	COG3465	dGTPase activity
C2I06_RS17080	COG1078	dGTPase activity
C2I06_RS17085	COG4844	belongs to the
C2I06_RS17090	COG0477	Major facilitator Superfamily
C2I06_RS17105	COG0280	phosphate acetyltransferase
C2I06_RS17110	COG3253	May function as heme-dependent peroxidase
C2I06_RS17120	COG2363	Small membrane protein
C2I06_RS17135	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C2I06_RS17150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2I06_RS17160	COG0314	molybdopterin synthase activity
C2I06_RS17165	COG0351	phosphomethylpyrimidine kinase
C2I06_RS17170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C2I06_RS17190	COG0561	phosphatase activity
C2I06_RS17195	COG1271	oxidase subunit
C2I06_RS17200	COG1294	oxidase, subunit
C2I06_RS17205	COG4988	ABC transporter
C2I06_RS17210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C2I06_RS17215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C2I06_RS17220	COG2226	methyltransferase
C2I06_RS17225	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS17230	COG1486	melibiose metabolic process
C2I06_RS17235	COG3610	response to peptide
C2I06_RS17240	COG2966	Psort location CytoplasmicMembrane, score
C2I06_RS17255	COG1131	(ABC) transporter
C2I06_RS17260	COG0686	Belongs to the AlaDH PNT family
C2I06_RS17265	COG2508	Transcriptional regulator
C2I06_RS17265	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C2I06_RS17275	COG1486	melibiose metabolic process
C2I06_RS17280	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2I06_RS17285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS17290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS17295	COG2188	Transcriptional regulator
C2I06_RS17305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C2I06_RS17310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C2I06_RS17320	COG0385	Bile acid
C2I06_RS17325	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2I06_RS17330	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS17335	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS17340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS17345	COG3711	transcriptional antiterminator
C2I06_RS17345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS17355	COG0446	pyridine nucleotide-disulphide oxidoreductase
C2I06_RS17405	COG2508	Transcriptional regulator
C2I06_RS17415	COG0477	Major facilitator Superfamily
C2I06_RS17420	COG0534	Mate efflux family protein
C2I06_RS17430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS17440	COG1609	Transcriptional regulator
C2I06_RS17455	COG1609	Transcriptional regulator
C2I06_RS17465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2I06_RS17470	COG1554	hydrolase, family 65, central catalytic
C2I06_RS17480	COG3833	ABC-type maltose transport systems, permease component
C2I06_RS17485	COG1175	transmembrane transport
C2I06_RS17490	COG2182	Extracellular solute-binding protein
C2I06_RS17495	COG1263	PTS System
C2I06_RS17495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS17500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C2I06_RS17505	COG1122	ATPase activity
C2I06_RS17510	COG4721	ABC-type cobalt transport system, permease component
C2I06_RS17515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C2I06_RS17525	COG3695	enzyme binding
C2I06_RS17535	COG0411	ABC transporter
C2I06_RS17545	COG0559	Belongs to the binding-protein-dependent transport system permease family
C2I06_RS17565	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS17575	COG4176	ABC-type proline glycine betaine transport system permease component
C2I06_RS17585	COG3507	Belongs to the glycosyl hydrolase 43 family
C2I06_RS17600	COG1073	alpha beta
C2I06_RS17610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2I06_RS17615	COG1653	transport
C2I06_RS17625	COG4209	transmembrane transport
C2I06_RS17630	COG0395	ABC-type sugar transport system, permease component
C2I06_RS17635	COG2207	Transcriptional regulator
C2I06_RS17640	COG1609	Transcriptional regulator
C2I06_RS17645	COG2721	sulfolactate sulfo-lyase activity
C2I06_RS17650	COG1904	glucuronate isomerase
C2I06_RS17655	COG0657	acetylesterase activity
C2I06_RS17655	COG2755	lipolytic protein G-D-S-L family
C2I06_RS17660	COG2755	lipolytic protein G-D-S-L family
C2I06_RS17675	COG2814	Major facilitator Superfamily
C2I06_RS17705	COG2072	flavoprotein involved in K transport
C2I06_RS17710	COG0753	catalase activity
C2I06_RS17740	COG2208	phosphoserine phosphatase activity
C2I06_RS17745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C2I06_RS17750	COG2205	protein histidine kinase activity
C2I06_RS17750	COG0784	Response regulator, receiver
C2I06_RS17750	COG2198	Histidine kinase
C2I06_RS17760	COG4608	Belongs to the ABC transporter superfamily
C2I06_RS17765	COG0444	Belongs to the ABC transporter superfamily
C2I06_RS17770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2I06_RS17775	COG0601	transmembrane transport
C2I06_RS17780	COG4166	transmembrane transport
C2I06_RS17790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C2I06_RS17795	COG4989	oxidoreductase activity
C2I06_RS17800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C2I06_RS17805	COG1320	monovalent cation:proton antiporter activity
C2I06_RS17810	COG2212	antiporter activity
C2I06_RS17815	COG1863	multisubunit Na H antiporter MnhE subunit
C2I06_RS17820	COG0651	ATP synthesis coupled electron transport
C2I06_RS17825	COG1006	Multisubunit Na H antiporter MnhC subunit
C2I06_RS17830	COG2111	Na H antiporter
C2I06_RS17845	COG0582	viral genome integration into host DNA
C2I06_RS17850	COG0124	histidyl-tRNA synthetase
C2I06_RS17855	COG3142	Participates in the control of copper homeostasis
C2I06_RS17860	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C2I06_RS17865	COG1609	Transcriptional regulator
C2I06_RS17870	COG3459	Glycosyltransferase 36 associated
C2I06_RS17880	COG0395	ABC-type sugar transport system, permease component
C2I06_RS17885	COG1175	transmembrane transport
C2I06_RS17895	COG5039	Polysaccharide pyruvyl transferase
C2I06_RS17900	COG1994	Peptidase M50
C2I06_RS17905	COG1397	ADP-ribosylglycohydrolase
C2I06_RS17925	COG4555	ABC transporter
C2I06_RS17935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C2I06_RS17940	COG0450	alkyl hydroperoxide reductase
C2I06_RS17945	COG3634	alkyl hydroperoxide reductase activity
C2I06_RS17965	COG4166	transmembrane transport
C2I06_RS17970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS17970	COG3711	transcriptional antiterminator
C2I06_RS17975	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS17985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS17990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS17995	COG3507	Belongs to the glycosyl hydrolase 43 family
C2I06_RS18000	COG0579	oxidoreductase
C2I06_RS18005	COG1464	Belongs to the NlpA lipoprotein family
C2I06_RS18015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C2I06_RS18020	COG1279	arginine transmembrane transporter activity
C2I06_RS18025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS18035	COG5566	PFAM Mor transcription activator
C2I06_RS18040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2I06_RS18045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2I06_RS18055	COG5002	protein histidine kinase activity
C2I06_RS18075	COG2824	Alkylphosphonate utilization operon protein PhnA
C2I06_RS18085	COG1126	abc transporter atp-binding protein
C2I06_RS18090	COG0765	amino acid transport
C2I06_RS18100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2I06_RS18105	COG2814	Major facilitator Superfamily
C2I06_RS18115	COG0733	neurotransmitter:sodium symporter activity
C2I06_RS18125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C2I06_RS18130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C2I06_RS18135	COG1696	Membrane protein involved in D-alanine export
C2I06_RS18140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C2I06_RS18150	COG0745	RESPONSE REGULATOR receiver
C2I06_RS18155	COG5002	protein histidine kinase activity
C2I06_RS18165	COG0697	spore germination
C2I06_RS18170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS18180	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2I06_RS18185	COG2169	Transcriptional regulator
C2I06_RS18195	COG1126	abc transporter atp-binding protein
C2I06_RS18200	COG0765	amino acid transport
C2I06_RS18205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C2I06_RS18215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS18220	COG0697	spore germination
C2I06_RS18245	COG2223	nitrite transmembrane transporter activity
C2I06_RS18250	COG0109	protoheme IX farnesyltransferase activity
C2I06_RS18255	COG0746	molybdenum cofactor guanylyltransferase activity
C2I06_RS18260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C2I06_RS18265	COG1763	Mo-molybdopterin cofactor biosynthetic process
C2I06_RS18275	COG0314	molybdopterin synthase activity
C2I06_RS18280	COG0303	'Molybdopterin
C2I06_RS18285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2I06_RS18290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C2I06_RS18300	COG2181	nitrate reductase activity
C2I06_RS18305	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C2I06_RS18310	COG1140	nitrate reductase beta subunit
C2I06_RS18315	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C2I06_RS18320	COG4149	molybdate abc transporter
C2I06_RS18325	COG0725	ABC transporter, periplasmic molybdate-binding protein
C2I06_RS18340	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS18360	COG1595	DNA-templated transcription, initiation
C2I06_RS18390	COG0577	efflux transmembrane transporter activity
C2I06_RS18395	COG1136	(ABC) transporter
C2I06_RS18400	COG2329	Antibiotic biosynthesis monooxygenase
C2I06_RS18465	COG4841	protein insertion into membrane
C2I06_RS18475	COG1846	Transcriptional regulator
C2I06_RS18480	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS18485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS18485	COG1263	PTS System
C2I06_RS18485	COG2190	(PTS) system
C2I06_RS18490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS18490	COG1263	PTS System
C2I06_RS18490	COG2190	(PTS) system
C2I06_RS18495	COG3711	transcriptional antiterminator
C2I06_RS18515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2I06_RS18535	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C2I06_RS18545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2I06_RS18550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C2I06_RS18555	COG4853	Protein conserved in bacteria
C2I06_RS18560	COG4863	YycH protein
C2I06_RS18565	COG5002	protein histidine kinase activity
C2I06_RS18570	COG0745	RESPONSE REGULATOR receiver
C2I06_RS18600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C2I06_RS18610	COG0305	Participates in initiation and elongation during chromosome replication
C2I06_RS18615	COG0359	binds to the 23S rRNA
C2I06_RS18620	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C2I06_RS18625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C2I06_RS18635	COG0360	Binds together with S18 to 16S ribosomal RNA
C2I06_RS18640	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS18645	COG0012	GTP binding
C2I06_RS18650	COG4481	Protein conserved in bacteria
C2I06_RS18655	COG0668	transmembrane transport
C2I06_RS18670	COG1475	DNA binding
C2I06_RS18675	COG1192	Involved in chromosome partitioning
C2I06_RS18685	COG1475	DNA binding
C2I06_RS18705	COG1847	R3H domain protein
C2I06_RS18715	COG0594	ribonuclease P activity
C2I06_RS18720	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C2I06_RS18730	COG0592	DNA-directed DNA polymerase activity
C2I06_RS18735	COG2501	S4 domain
C2I06_RS18740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C2I06_RS18750	COG0187	DNA topoisomerase II activity
C2I06_RS18755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C2I06_RS18760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C2I06_RS18795	COG0516	GMP reductase activity
C2I06_RS18795	COG0517	IMP dehydrogenase activity
C2I06_RS18810	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C2I06_RS18815	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C2I06_RS18825	COG1428	Deoxynucleoside kinase
C2I06_RS18830	COG1428	Deoxynucleoside kinase
C2I06_RS18835	COG0352	thiamine-phosphate diphosphorylase activity
C2I06_RS18845	COG2104	thiamine diphosphate biosynthetic process
C2I06_RS18850	COG2022	thiamine diphosphate biosynthetic process
C2I06_RS18855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C2I06_RS18860	COG3858	chitin binding
C2I06_RS18860	COG1388	LysM domain
C2I06_RS18865	COG1335	isochorismatase
C2I06_RS18870	COG0590	tRNA wobble adenosine to inosine editing
C2I06_RS18880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C2I06_RS18885	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C2I06_RS18890	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C2I06_RS18940	COG1982	Orn Lys Arg decarboxylase major
C2I06_RS18950	COG3870	Protein conserved in bacteria
C2I06_RS18955	COG1728	Protein conserved in bacteria
C2I06_RS18960	COG0470	DNA polymerase III
C2I06_RS18965	COG1774	PSP1 C-terminal conserved region
C2I06_RS18970	COG4467	Involved in initiation control of chromosome replication
C2I06_RS18975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C2I06_RS18980	COG2827	Endonuclease containing a URI domain
C2I06_RS18985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C2I06_RS18990	COG2002	toxin-antitoxin pair type II binding
C2I06_RS19000	COG0084	hydrolase, TatD family'
C2I06_RS19005	COG3584	3D domain protein
C2I06_RS19005	COG3583	domain protein
C2I06_RS19015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C2I06_RS19025	COG4466	Protein conserved in bacteria
C2I06_RS19035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C2I06_RS19040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C2I06_RS19045	COG0251	oxidation-reduction process
C2I06_RS19050	COG2088	sporulation resulting in formation of a cellular spore
C2I06_RS19055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C2I06_RS19060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C2I06_RS19065	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C2I06_RS19080	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C2I06_RS19085	COG2002	toxin-antitoxin pair type II binding
C2I06_RS19090	COG2188	Transcriptional regulator
C2I06_RS19100	COG2244	polysaccharide biosynthetic process
C2I06_RS19105	COG3956	TIGRFAM MazG family protein
C2I06_RS19110	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C2I06_RS19125	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C2I06_RS19130	COG1098	S1 RNA binding domain
C2I06_RS19140	COG2208	phosphoserine phosphatase activity
C2I06_RS19145	COG2304	oxidoreductase activity
C2I06_RS19150	COG0515	serine threonine protein kinase
C2I06_RS19155	COG0037	tRNA processing
C2I06_RS19160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C2I06_RS19165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C2I06_RS19170	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C2I06_RS19175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C2I06_RS19180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2I06_RS19185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C2I06_RS19190	COG0512	Glutamine amidotransferase of anthranilate synthase
C2I06_RS19195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C2I06_RS19200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C2I06_RS19205	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C2I06_RS19210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C2I06_RS19215	COG1396	sequence-specific DNA binding
C2I06_RS19220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2I06_RS19225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C2I06_RS19310	COG3880	PFAM UvrB UvrC protein
C2I06_RS19315	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C2I06_RS19320	COG0542	response to heat
C2I06_RS19325	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C2I06_RS19330	COG4956	integral membrane protein (PIN domain superfamily)
C2I06_RS19335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C2I06_RS19340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C2I06_RS19345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C2I06_RS19350	COG1045	serine acetyltransferase
C2I06_RS19355	COG0215	cysteine-tRNA ligase activity
C2I06_RS19365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C2I06_RS19370	COG3688	RNA-binding protein containing a PIN domain
C2I06_RS19380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C2I06_RS19385	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C2I06_RS19390	COG0250	Participates in transcription elongation, termination and antitermination
C2I06_RS19395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C2I06_RS19400	COG0081	regulation of translation
C2I06_RS19405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C2I06_RS19410	COG0222	ribosome binding
C2I06_RS19415	COG2813	Specifically methylates the guanine in position
C2I06_RS19425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C2I06_RS19430	COG1358	cellular component organization or biogenesis
C2I06_RS19435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C2I06_RS19440	COG0049	tRNA binding
C2I06_RS19450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C2I06_RS19455	COG0051	transcription antitermination factor activity, RNA binding
C2I06_RS19460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C2I06_RS19465	COG0088	Forms part of the polypeptide exit tunnel
C2I06_RS19475	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C2I06_RS19480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C2I06_RS19495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C2I06_RS19500	COG0255	Belongs to the universal ribosomal protein uL29 family
C2I06_RS19505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C2I06_RS19535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C2I06_RS19540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C2I06_RS19545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C2I06_RS19550	COG1841	ribosomal large subunit assembly
C2I06_RS19560	COG0201	protein transport
C2I06_RS19565	COG0563	adenylate kinase activity
C2I06_RS19570	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C2I06_RS19575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C2I06_RS19580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C2I06_RS19590	COG0202	RNA polymerase activity
C2I06_RS19595	COG0203	ribosomal protein L17
C2I06_RS19600	COG1122	ATPase activity
C2I06_RS19605	COG1122	ATPase activity
C2I06_RS19610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C2I06_RS19620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C2I06_RS19625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C2I06_RS19640	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS19645	COG1263	PTS System
C2I06_RS19645	COG2190	(PTS) system
C2I06_RS19645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS19655	COG2190	(PTS) system
C2I06_RS19705	COG0860	N-Acetylmuramoyl-L-alanine amidase
C2I06_RS19710	COG0489	protein tyrosine kinase activity
C2I06_RS19720	COG0726	polysaccharide deacetylase
C2I06_RS19795	COG1595	DNA-templated transcription, initiation
C2I06_RS19800	COG5662	AntiSigma factor
C2I06_RS19805	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C2I06_RS19810	COG4856	YbbR-like protein
C2I06_RS19815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C2I06_RS19820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C2I06_RS19840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C2I06_RS19850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C2I06_RS19900	COG0463	Glycosyl transferase, family 2
C2I06_RS19940	COG1846	Transcriptional regulator
C2I06_RS19965	COG1846	Transcriptional regulator
C2I06_RS19975	COG0778	Nitroreductase
C2I06_RS19990	COG0745	RESPONSE REGULATOR receiver
C2I06_RS19995	COG0642	Histidine kinase
C2I06_RS20015	COG1733	regulation of RNA biosynthetic process
C2I06_RS20025	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS20040	COG2807	transmembrane transport
C2I06_RS20050	COG4607	ABC-type enterochelin transport system periplasmic component
C2I06_RS20055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS20060	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS20065	COG1120	ATPase activity
C2I06_RS20080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C2I06_RS20090	COG0730	response to heat
C2I06_RS20105	COG2210	Belongs to the sulfur carrier protein TusA family
C2I06_RS20115	COG1114	Component of the transport system for branched-chain amino acids
C2I06_RS20120	COG2378	regulation of single-species biofilm formation
C2I06_RS20125	COG0519	Catalyzes the synthesis of GMP from XMP
C2I06_RS20130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C2I06_RS20140	COG1595	DNA-templated transcription, initiation
C2I06_RS20145	COG0492	ferredoxin-NADP+ reductase activity
C2I06_RS20150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C2I06_RS20160	COG0456	acetyltransferase
C2I06_RS20185	COG1595	DNA-templated transcription, initiation
C2I06_RS20195	COG1316	TRANSCRIPTIONal
C2I06_RS20205	COG0454	-acetyltransferase
C2I06_RS20230	COG1011	Hydrolase
C2I06_RS20240	COG1609	Transcriptional regulator
C2I06_RS20245	COG2182	Extracellular solute-binding protein
C2I06_RS20250	COG1175	transmembrane transport
C2I06_RS20255	COG3833	ABC-type maltose transport systems, permease component
C2I06_RS20260	COG1874	Beta-galactosidase
C2I06_RS20265	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS20275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C2I06_RS20280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C2I06_RS20285	COG0583	DNA-binding transcription factor activity
C2I06_RS20300	COG0175	sulfate reduction
C2I06_RS20310	COG2046	Belongs to the sulfate adenylyltransferase family
C2I06_RS20315	COG0529	Catalyzes the synthesis of activated sulfate
C2I06_RS20335	COG2205	protein histidine kinase activity
C2I06_RS20335	COG0784	Response regulator, receiver
C2I06_RS20340	COG5002	protein histidine kinase activity
C2I06_RS20355	COG1309	transcriptional regulator
C2I06_RS20360	COG2814	Major facilitator Superfamily
C2I06_RS20385	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS20400	COG2404	hydrolase activity, acting on ester bonds
C2I06_RS20415	COG1657	PFAM Prenyltransferase squalene oxidase
C2I06_RS20420	COG0017	Asparaginyl-tRNA synthetase
C2I06_RS20425	COG3386	PFAM SMP-30 Gluconolaconase
C2I06_RS20435	COG0659	secondary active sulfate transmembrane transporter activity
C2I06_RS20445	COG3620	sequence-specific DNA binding
C2I06_RS20455	COG1263	PTS System
C2I06_RS20455	COG2190	(PTS) system
C2I06_RS20455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS20480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS20490	COG1054	Belongs to the UPF0176 family
C2I06_RS20500	COG4149	molybdate abc transporter
C2I06_RS20505	COG0725	ABC transporter, periplasmic molybdate-binding protein
C2I06_RS20510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C2I06_RS20545	COG1252	NADH dehydrogenase
C2I06_RS20560	COG1122	ATPase activity
C2I06_RS20580	COG2244	polysaccharide biosynthetic process
C2I06_RS20585	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS20585	COG0297	glycogen (starch) synthase activity
C2I06_RS20590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C2I06_RS20595	COG3307	-O-antigen
C2I06_RS20600	COG3206	protein involved in exopolysaccharide biosynthesis
C2I06_RS20605	COG1215	transferase activity, transferring glycosyl groups
C2I06_RS20610	COG0438	transferase activity, transferring glycosyl groups
C2I06_RS20615	COG1959	2 iron, 2 sulfur cluster binding
C2I06_RS20620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C2I06_RS20635	COG2362	D-Aminopeptidase
C2I06_RS20640	COG0601	transmembrane transport
C2I06_RS20645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2I06_RS20650	COG0444	Belongs to the ABC transporter superfamily
C2I06_RS20655	COG4166	transmembrane transport
C2I06_RS20660	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2I06_RS20665	COG4948	Mandelate Racemase Muconate Lactonizing
C2I06_RS20670	COG0791	NLP P60 protein
C2I06_RS20675	COG4608	Belongs to the ABC transporter superfamily
C2I06_RS20685	COG1120	ATPase activity
C2I06_RS20700	COG0667	Aldo Keto reductase
C2I06_RS20705	COG0129	dihydroxy-acid dehydratase activity
C2I06_RS20710	COG0628	permease
C2I06_RS20715	COG0789	Transcriptional regulator
C2I06_RS20720	COG1253	flavin adenine dinucleotide binding
C2I06_RS20730	COG3711	transcriptional antiterminator
C2I06_RS20735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS20740	COG0246	Mannitol dehydrogenase
C2I06_RS20745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C2I06_RS20755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C2I06_RS20770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS20775	COG4605	iron ion homeostasis
C2I06_RS20780	COG4604	ABC transporter, ATP-binding protein
C2I06_RS20785	COG4607	ABC-type enterochelin transport system periplasmic component
C2I06_RS20790	COG0673	inositol 2-dehydrogenase activity
C2I06_RS20795	COG1940	carbohydrate kinase activity
C2I06_RS20800	COG5002	protein histidine kinase activity
C2I06_RS20800	COG3850	Histidine kinase
C2I06_RS20805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C2I06_RS20810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C2I06_RS20840	COG1176	ABC-type spermidine putrescine transport system, permease component I
C2I06_RS20845	COG1177	transmembrane transport
C2I06_RS20850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C2I06_RS20875	COG2861	carbohydrate metabolic process
C2I06_RS20880	COG0668	transmembrane transport
C2I06_RS20885	COG0569	domain protein
C2I06_RS20890	COG0783	Belongs to the Dps family
C2I06_RS20895	COG0772	Belongs to the SEDS family
C2I06_RS20900	COG2239	Acts as a magnesium transporter
C2I06_RS20905	COG0402	S-adenosylhomocysteine deaminase activity
C2I06_RS20915	COG1489	DNA binding
C2I06_RS20920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2I06_RS20925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS20930	COG1120	ATPase activity
C2I06_RS20935	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
C2I06_RS20950	COG1492	cobalamin metabolic process
C2I06_RS20955	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C2I06_RS20960	COG0588	phosphoglycerate mutase activity
C2I06_RS20970	COG2096	Adenosyltransferase
C2I06_RS20990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C2I06_RS21000	COG0513	Belongs to the DEAD box helicase family
C2I06_RS21005	COG3402	PFAM membrane-flanked domain
C2I06_RS21010	COG3428	Bacterial PH domain
C2I06_RS21015	COG0705	Rhomboid family
C2I06_RS21020	COG0736	holo-[acyl-carrier-protein] synthase activity
C2I06_RS21025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C2I06_RS21035	COG0864	Transcriptional regulator
C2I06_RS21040	COG2337	Toxic component of a toxin-antitoxin (TA) module
C2I06_RS21045	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS21050	COG2172	sigma factor antagonist activity
C2I06_RS21055	COG2208	phosphoserine phosphatase activity
C2I06_RS21060	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS21065	COG2172	sigma factor antagonist activity
C2I06_RS21070	COG1191	sigma factor activity
C2I06_RS21075	COG2208	phosphoserine phosphatase activity
C2I06_RS21080	COG2183	response to ionizing radiation
C2I06_RS21090	COG3091	SprT-like family
C2I06_RS21170	COG0802	atpase or kinase
C2I06_RS21175	COG1214	PFAM Peptidase M22, glycoprotease
C2I06_RS21180	COG0456	acetyltransferase
C2I06_RS21190	COG0488	(ABC) transporter
C2I06_RS21195	COG0315	cyclic pyranopterin monophosphate synthase activity
C2I06_RS21200	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C2I06_RS21210	COG1266	CAAX protease self-immunity
C2I06_RS21215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C2I06_RS21220	COG0459	protein refolding
C2I06_RS21230	COG1396	sequence-specific DNA binding
C2I06_RS21300	COG0346	lactoylglutathione lyase activity
C2I06_RS21345	COG3715	PTS system
C2I06_RS21350	COG3716	PTS system mannose fructose sorbose family IID component
C2I06_RS21355	COG0673	inositol 2-dehydrogenase activity
C2I06_RS21360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C2I06_RS21365	COG0277	FAD linked oxidase domain protein
C2I06_RS21385	COG0733	neurotransmitter:sodium symporter activity
C2I06_RS21395	COG3290	protein histidine kinase activity
C2I06_RS21400	COG4565	transcriptional regulatory protein
C2I06_RS21410	COG0281	malic enzyme
C2I06_RS21425	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C2I06_RS21440	COG3842	ATPase activity
C2I06_RS21450	COG1533	DNA photolyase activity
C2I06_RS21460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C2I06_RS21465	COG3871	stress protein (general stress protein 26)
C2I06_RS21470	COG4294	response to UV
C2I06_RS21475	COG4294	response to UV
C2I06_RS21485	COG2211	Major facilitator Superfamily
C2I06_RS21495	COG0583	DNA-binding transcription factor activity
C2I06_RS21500	COG1473	amidohydrolase
C2I06_RS21505	COG1288	antiporter activity
C2I06_RS21515	COG0702	epimerase
C2I06_RS21520	COG2188	Transcriptional regulator
C2I06_RS21525	COG2222	sugar isomerase
C2I06_RS21530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS21535	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C2I06_RS21565	COG1312	Catalyzes the dehydration of D-mannonate
C2I06_RS21575	COG1904	glucuronate isomerase
C2I06_RS21580	COG0246	Mannitol dehydrogenase
C2I06_RS21585	COG1263	PTS System
C2I06_RS21585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS21585	COG2190	(PTS) system
C2I06_RS21590	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS21595	COG3711	transcriptional antiterminator
C2I06_RS21600	COG2310	stress, protein
C2I06_RS21605	COG0714	Associated with various cellular activities
C2I06_RS21610	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C2I06_RS21615	COG1305	Transglutaminase-like
C2I06_RS21620	COG0519	Catalyzes the synthesis of GMP from XMP
C2I06_RS21620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C2I06_RS21625	COG0730	response to heat
C2I06_RS21630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C2I06_RS21635	COG0517	IMP dehydrogenase activity
C2I06_RS21640	COG0574	Belongs to the PEP-utilizing enzyme family
C2I06_RS21640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C2I06_RS21645	COG2252	PERMEase
C2I06_RS21650	COG3711	transcriptional antiterminator
C2I06_RS21655	COG1263	PTS System
C2I06_RS21655	COG2190	(PTS) system
C2I06_RS21655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS21675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C2I06_RS21720	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C2I06_RS21730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C2I06_RS21735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C2I06_RS21740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C2I06_RS21745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C2I06_RS21750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C2I06_RS21755	COG0047	phosphoribosylformylglycinamidine synthase activity
C2I06_RS21765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C2I06_RS21770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C2I06_RS21775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C2I06_RS21780	COG0138	bifunctional purine biosynthesis protein purh
C2I06_RS21785	COG0151	Belongs to the GarS family
C2I06_RS21790	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS21805	COG1470	cell adhesion involved in biofilm formation
C2I06_RS21810	COG4496	protein, YerC YecD
C2I06_RS21815	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C2I06_RS21820	COG0210	DNA helicase
C2I06_RS21825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C2I06_RS21830	COG4851	CamS sex pheromone cAM373 precursor
C2I06_RS21835	COG5506	Protein of unknown function (DUF1694)
C2I06_RS21840	COG1764	response to oxidative stress
C2I06_RS21845	COG1846	Transcriptional regulator
C2I06_RS21850	COG2720	vancomycin resistance protein
C2I06_RS21855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C2I06_RS21865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C2I06_RS21885	COG1595	DNA-templated transcription, initiation
C2I06_RS21905	COG1597	lipid kinase activity
C2I06_RS21915	COG0583	DNA-binding transcription factor activity
C2I06_RS21920	COG2814	Major facilitator Superfamily
C2I06_RS21925	COG0604	alcohol dehydrogenase
C2I06_RS21940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C2I06_RS21945	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C2I06_RS21950	COG2205	protein histidine kinase activity
C2I06_RS21960	COG0456	acetyltransferase
C2I06_RS21965	COG1388	LysM domain
C2I06_RS21965	COG3584	3D domain protein
C2I06_RS21985	COG2972	Histidine kinase
C2I06_RS22010	COG0166	Belongs to the GPI family
C2I06_RS22015	COG1733	regulation of RNA biosynthetic process
C2I06_RS22020	COG2514	catechol 2,3-dioxygenase activity
C2I06_RS22025	COG1366	Belongs to the anti-sigma-factor antagonist family
C2I06_RS22035	COG1785	Belongs to the alkaline phosphatase family
C2I06_RS22040	COG1794	racemase activity, acting on amino acids and derivatives
C2I06_RS22045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS22050	COG3480	Lon protease (S16) C-terminal proteolytic domain
C2I06_RS22060	COG3279	Response regulator of the LytR AlgR family
C2I06_RS22080	COG1695	Transcriptional regulator
C2I06_RS22105	COG0515	serine threonine protein kinase
C2I06_RS22110	COG1132	(ABC) transporter
C2I06_RS22125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C2I06_RS22135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C2I06_RS22145	COG2814	Major facilitator Superfamily
C2I06_RS22150	COG0527	aspartate kinase activity
C2I06_RS22160	COG0765	amino acid transport
C2I06_RS22165	COG1126	abc transporter atp-binding protein
C2I06_RS22175	COG1473	amidohydrolase
C2I06_RS22180	COG1473	amidohydrolase
C2I06_RS22185	COG0444	Belongs to the ABC transporter superfamily
C2I06_RS22190	COG4608	Belongs to the ABC transporter superfamily
C2I06_RS22195	COG0601	transmembrane transport
C2I06_RS22200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C2I06_RS22210	COG1132	(ABC) transporter
C2I06_RS22215	COG1132	(ABC) transporter
C2I06_RS22220	COG2357	RelA SpoT domain protein
C2I06_RS22225	COG0513	Belongs to the DEAD box helicase family
C2I06_RS22240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C2I06_RS22245	COG0697	spore germination
C2I06_RS22275	COG2197	response regulator
C2I06_RS22280	COG2244	polysaccharide biosynthetic process
C2I06_RS22295	COG0598	Magnesium transport protein CorA
C2I06_RS22300	COG1607	acyl-coa hydrolase
C2I06_RS22310	COG0670	Belongs to the BI1 family
C2I06_RS22315	COG1970	mechanosensitive ion channel activity
C2I06_RS22320	COG1254	Belongs to the acylphosphatase family
C2I06_RS22330	COG2309	aminopeptidase activity
C2I06_RS22335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C2I06_RS22340	COG0551	DNA topoisomerase type I activity
C2I06_RS22340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C2I06_RS22350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C2I06_RS22355	COG1360	Flagellar Motor Protein
C2I06_RS22360	COG1522	sequence-specific DNA binding
C2I06_RS22360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C2I06_RS22365	COG2313	pseudouridylate synthase activity
C2I06_RS22370	COG1396	sequence-specific DNA binding
C2I06_RS22385	COG1396	sequence-specific DNA binding
C2I06_RS22390	COG2188	Transcriptional regulator
C2I06_RS22395	COG0693	protein deglycase activity
C2I06_RS22400	COG0024	Methionine aminopeptidase
C2I06_RS22405	COG4840	Belongs to the UPF0435 family
C2I06_RS22410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C2I06_RS22420	COG1295	ribonuclease BN
C2I06_RS22425	COG2217	Heavy metal translocating P-type atpase
C2I06_RS22430	COG0477	Major facilitator Superfamily
C2I06_RS22435	COG0387	Pfam Sodium calcium exchanger
C2I06_RS22440	COG2364	Membrane
C2I06_RS22450	COG0535	radical SAM domain protein
C2I06_RS22460	COG2365	Tyrosine phosphatase family
C2I06_RS22465	COG1309	transcriptional regulator
C2I06_RS22485	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C2I06_RS22490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS22500	COG1959	2 iron, 2 sulfur cluster binding
C2I06_RS22515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C2I06_RS22520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C2I06_RS22585	COG1472	Belongs to the glycosyl hydrolase 3 family
C2I06_RS22595	COG0463	Glycosyl transferase, family 2
C2I06_RS22600	COG0562	UDP-galactopyranose mutase
C2I06_RS22640	COG4842	Belongs to the WXG100 family
C2I06_RS22645	COG5417	Belongs to the EsaB family
C2I06_RS22650	COG4499	WXG100 protein secretion system (Wss), protein YukC
C2I06_RS22655	COG1674	ftsk spoiiie
C2I06_RS22655	COG0433	COG0433 Predicted ATPase
C2I06_RS22660	COG1511	domain protein
C2I06_RS22670	COG0488	(ABC) transporter
C2I06_RS22675	COG3940	Belongs to the glycosyl hydrolase 43 family
C2I06_RS22685	COG0737	Belongs to the 5'-nucleotidase family
C2I06_RS22695	COG4191	Histidine kinase
C2I06_RS22705	COG4807	Protein conserved in bacteria
C2I06_RS22715	COG0583	DNA-binding transcription factor activity
C2I06_RS22745	COG1125	glycine betaine transport
C2I06_RS22745	COG0517	IMP dehydrogenase activity
C2I06_RS22750	COG1174	glycine betaine transport
C2I06_RS22770	COG0573	inorganic phosphate transmembrane transporter activity
C2I06_RS22775	COG0581	inorganic phosphate transmembrane transporter activity
C2I06_RS22780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C2I06_RS22800	COG4753	response regulator
C2I06_RS22800	COG2207	Transcriptional regulator
C2I06_RS22805	COG4213	ABC transporter substrate-binding protein
C2I06_RS22810	COG1129	ABC transporter
C2I06_RS22815	COG4214	carbohydrate transport
C2I06_RS22820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2I06_RS22825	COG2211	Major facilitator Superfamily
C2I06_RS22845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C2I06_RS22855	COG0702	epimerase
C2I06_RS22860	COG1733	regulation of RNA biosynthetic process
C2I06_RS22870	COG0765	amino acid transport
C2I06_RS22875	COG0488	(ABC) transporter
C2I06_RS22885	COG1619	proteins homologs of microcin C7 resistance protein MccF
C2I06_RS22890	COG0322	excinuclease ABC activity
C2I06_RS22910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C2I06_RS22915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C2I06_RS22920	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C2I06_RS22925	COG4260	virion core protein, lumpy skin disease virus
C2I06_RS22935	COG0534	Mate efflux family protein
C2I06_RS22960	COG3534	alpha-L-arabinofuranosidase
C2I06_RS22970	COG1780	Probably involved in ribonucleotide reductase function
C2I06_RS22975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2I06_RS22980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C2I06_RS22985	COG1595	DNA-templated transcription, initiation
C2I06_RS23000	COG1132	(ABC) transporter
C2I06_RS23005	COG1132	(ABC) transporter
C2I06_RS23030	COG0840	transmembrane signaling receptor activity
C2I06_RS23050	COG3275	phosphorelay sensor kinase activity
C2I06_RS23055	COG3279	Response regulator of the LytR AlgR family
C2I06_RS23060	COG2223	nitrite transmembrane transporter activity
C2I06_RS23070	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C2I06_RS23075	COG3853	Toxic anion resistance protein (TelA)
C2I06_RS23080	COG0384	phenazine biosynthesis protein PhzF
C2I06_RS23085	COG4708	membrane
C2I06_RS23095	COG1136	(ABC) transporter
C2I06_RS23100	COG1136	(ABC) transporter
C2I06_RS23100	COG0577	efflux transmembrane transporter activity
C2I06_RS23105	COG0745	RESPONSE REGULATOR receiver
C2I06_RS23110	COG5002	protein histidine kinase activity
C2I06_RS23110	COG3850	Histidine kinase
C2I06_RS23115	COG1607	acyl-coa hydrolase
C2I06_RS23130	COG0683	leucine binding
C2I06_RS23155	COG2706	6-phosphogluconolactonase activity
C2I06_RS23160	COG3507	Belongs to the glycosyl hydrolase 43 family
C2I06_RS23170	COG2137	regulation of response to DNA damage stimulus
C2I06_RS23190	COG1988	membrane-bound metal-dependent
C2I06_RS23195	COG1194	a g-specific adenine glycosylase
C2I06_RS23205	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS23225	COG1132	(ABC) transporter
C2I06_RS23230	COG4129	membrane
C2I06_RS23235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C2I06_RS23245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C2I06_RS23250	COG0735	belongs to the Fur family
C2I06_RS23360	COG0398	Pfam SNARE associated Golgi protein
C2I06_RS23365	COG0745	RESPONSE REGULATOR receiver
C2I06_RS23370	COG0642	Histidine kinase
C2I06_RS23370	COG5002	protein histidine kinase activity
C2I06_RS23390	COG1132	(ABC) transporter
C2I06_RS23400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C2I06_RS23425	COG1447	Phosphotransferase system cellobiose-specific component IIA
C2I06_RS23440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C2I06_RS23445	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS23450	COG3711	transcriptional antiterminator
C2I06_RS23450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C2I06_RS23495	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C2I06_RS23510	COG1304	FMN binding
C2I06_RS23520	COG1846	Transcriptional regulator
C2I06_RS23535	COG0477	Major facilitator Superfamily
C2I06_RS23540	COG3443	Belongs to the bacterial solute-binding protein 9 family
C2I06_RS23545	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2I06_RS23545	COG0803	Belongs to the bacterial solute-binding protein 9 family
C2I06_RS23570	COG0456	acetyltransferase
C2I06_RS23570	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C2I06_RS23575	COG0789	Transcriptional regulator
C2I06_RS23580	COG0697	spore germination
C2I06_RS23590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2I06_RS23595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS23600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS23610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C2I06_RS23615	COG4977	sequence-specific DNA binding
C2I06_RS23620	COG2755	lipolytic protein G-D-S-L family
C2I06_RS23625	COG2207	Transcriptional regulator
C2I06_RS23630	COG1653	transport
C2I06_RS23635	COG4209	transmembrane transport
C2I06_RS23640	COG0395	ABC-type sugar transport system, permease component
C2I06_RS23655	COG5578	integral membrane protein
C2I06_RS23660	COG0745	RESPONSE REGULATOR receiver
C2I06_RS23665	COG2205	protein histidine kinase activity
C2I06_RS23670	COG1136	(ABC) transporter
C2I06_RS23680	COG1902	pentaerythritol trinitrate reductase activity
C2I06_RS23685	COG3711	transcriptional antiterminator
C2I06_RS23690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS23690	COG2190	(PTS) system
C2I06_RS23690	COG1263	PTS System
C2I06_RS23695	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS23700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C2I06_RS23705	COG1984	allophanate hydrolase subunit 2
C2I06_RS23710	COG2814	Major facilitator Superfamily
C2I06_RS23730	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C2I06_RS23765	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS23815	COG0745	RESPONSE REGULATOR receiver
C2I06_RS23840	COG1846	Transcriptional regulator
C2I06_RS23845	COG0346	lactoylglutathione lyase activity
C2I06_RS23850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C2I06_RS23855	COG0346	lactoylglutathione lyase activity
C2I06_RS23860	COG0400	carboxylic ester hydrolase activity
C2I06_RS23865	COG0655	NAD(P)H dehydrogenase (quinone) activity
C2I06_RS23880	COG2391	methyltransferase activity
C2I06_RS23895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C2I06_RS23900	COG0431	NADPH-dependent FMN reductase
C2I06_RS23915	COG2972	Histidine kinase
C2I06_RS23920	COG2207	Transcriptional regulator
C2I06_RS23920	COG4753	response regulator
C2I06_RS23925	COG2814	Major facilitator Superfamily
C2I06_RS23925	COG0477	Major facilitator Superfamily
C2I06_RS23935	COG0741	lytic transglycosylase activity
C2I06_RS23940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C2I06_RS23955	COG4221	oxidoreductase activity
C2I06_RS23960	COG0789	Transcriptional regulator
C2I06_RS23970	COG1733	regulation of RNA biosynthetic process
C2I06_RS23985	COG0586	Pfam SNARE associated Golgi protein
C2I06_RS24000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C2I06_RS24015	COG1063	alcohol dehydrogenase
C2I06_RS24030	COG2116	formate transmembrane transporter activity
C2I06_RS24045	COG3382	B3 4 domain protein
C2I06_RS24050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C2I06_RS24065	COG0778	Nitroreductase
C2I06_RS24070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C2I06_RS24075	COG2766	serine protein kinase
C2I06_RS24100	COG2832	Protein of unknown function (DUF454)
C2I06_RS24115	COG0667	Aldo Keto reductase
C2I06_RS24125	COG1737	Transcriptional regulator
C2I06_RS24130	COG2723	6-phospho-beta-galactosidase activity
C2I06_RS24135	COG1263	PTS System
C2I06_RS24135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C2I06_RS24135	COG2190	(PTS) system
C2I06_RS24140	COG0641	radical SAM
C2I06_RS24160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C2I06_RS24165	COG4977	sequence-specific DNA binding
C2I06_RS24165	COG1917	Cupin 2, conserved barrel domain protein
C2I06_RS24180	COG0500	methyltransferase
C2I06_RS24185	COG1733	regulation of RNA biosynthetic process
C2I06_RS24225	COG0583	DNA-binding transcription factor activity
C2I06_RS24235	COG0662	Cupin 2, conserved barrel domain protein
C2I06_RS24285	COG1733	regulation of RNA biosynthetic process
C2I06_RS24290	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS24315	COG2329	Antibiotic biosynthesis monooxygenase
C2I06_RS24320	COG2207	Transcriptional regulator
C2I06_RS24320	COG1917	Cupin 2, conserved barrel domain protein
C2I06_RS24325	COG0697	spore germination
C2I06_RS24330	COG2315	Protein conserved in bacteria
C2I06_RS24335	COG2207	Transcriptional regulator
C2I06_RS24340	COG2211	Major facilitator Superfamily
C2I06_RS24345	COG3250	beta-galactosidase activity
C2I06_RS24355	COG1312	Catalyzes the dehydration of D-mannonate
C2I06_RS24360	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS24365	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C2I06_RS24375	COG2197	response regulator
C2I06_RS24380	COG4585	Histidine kinase
C2I06_RS24385	COG3239	Fatty acid desaturase
C2I06_RS24395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C2I06_RS24405	COG1396	sequence-specific DNA binding
C2I06_RS24420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C2I06_RS24445	COG0745	RESPONSE REGULATOR receiver
C2I06_RS24450	COG5002	protein histidine kinase activity
C2I06_RS24455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS24465	COG0306	phosphate transporter
C2I06_RS24470	COG1392	Phosphate transport regulator
C2I06_RS24475	COG1028	Short-chain dehydrogenase reductase Sdr
C2I06_RS24480	COG0656	L-ascorbic acid biosynthetic process
C2I06_RS24485	COG2261	transglycosylase associated protein
C2I06_RS24490	COG0564	pseudouridine synthase activity
C2I06_RS24500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C2I06_RS24510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C2I06_RS24510	COG3153	acetyltransferase
C2I06_RS24530	COG2252	PERMEase
C2I06_RS24545	COG0583	DNA-binding transcription factor activity
C2I06_RS24550	COG1309	transcriptional regulator
C2I06_RS24555	COG2076	Multidrug Resistance protein
C2I06_RS24585	COG2378	regulation of single-species biofilm formation
C2I06_RS24630	COG1694	Mazg nucleotide pyrophosphohydrolase
C2I06_RS24635	COG0789	Transcriptional regulator
C2I06_RS24635	COG4978	Transcriptional regulator
C2I06_RS24640	COG1811	Na channel or pump
C2I06_RS24645	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C2I06_RS24650	COG1131	(ABC) transporter
C2I06_RS24660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C2I06_RS24665	COG0598	Magnesium transport protein CorA
C2I06_RS24670	COG0745	RESPONSE REGULATOR receiver
C2I06_RS24675	COG1253	flavin adenine dinucleotide binding
C2I06_RS24680	COG1253	flavin adenine dinucleotide binding
C2I06_RS24685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C2I06_RS24690	COG0840	transmembrane signaling receptor activity
C2I06_RS24690	COG5278	phosphoserine phosphatase activity
C2I06_RS24705	COG2814	Major facilitator Superfamily
C2I06_RS24710	COG1132	(ABC) transporter
C2I06_RS24715	COG1132	(ABC) transporter
C2I06_RS24720	COG2819	hydrolase of the alpha beta superfamily
C2I06_RS24725	COG2207	Transcriptional regulator
C2I06_RS24725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2I06_RS24730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C2I06_RS24735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS24740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C2I06_RS24745	COG2819	hydrolase of the alpha beta superfamily
C2I06_RS24765	COG3842	ATPase activity
C2I06_RS24770	COG2508	Transcriptional regulator
C2I06_RS24775	COG0189	ligase activity
C2I06_RS24780	COG0189	ligase activity