locus-tag	class	description
ABC_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABC_RS00010	COG0592	DNA-directed DNA polymerase activity
ABC_RS00015	COG2501	S4 domain
ABC_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABC_RS00030	COG0187	DNA topoisomerase II activity
ABC_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABC_RS00040	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS00070	COG0517	IMP dehydrogenase activity
ABC_RS00070	COG0516	GMP reductase activity
ABC_RS00080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC_RS00085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABC_RS00090	COG2508	Transcriptional regulator
ABC_RS00095	COG3829	transcription factor binding
ABC_RS00100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC_RS00110	COG1757	Na H antiporter
ABC_RS00120	COG0006	proline dipeptidase activity
ABC_RS00140	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS00150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC_RS00155	COG0765	amino acid transport
ABC_RS00165	COG4608	Belongs to the ABC transporter superfamily
ABC_RS00170	COG0444	Belongs to the ABC transporter superfamily
ABC_RS00175	COG0601	transmembrane transport
ABC_RS00180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS00195	COG0590	tRNA wobble adenosine to inosine editing
ABC_RS00200	COG0740	serine-type endopeptidase activity
ABC_RS00210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABC_RS00215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABC_RS00220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABC_RS00255	COG4191	Histidine kinase
ABC_RS00260	COG2204	response regulator
ABC_RS00270	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS00285	COG1982	Orn Lys Arg decarboxylase major
ABC_RS00290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABC_RS00295	COG3870	Protein conserved in bacteria
ABC_RS00300	COG0470	DNA polymerase III
ABC_RS00305	COG1774	PSP1 C-terminal conserved region
ABC_RS00310	COG4467	Involved in initiation control of chromosome replication
ABC_RS00315	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABC_RS00320	COG2827	Endonuclease containing a URI domain
ABC_RS00325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABC_RS00330	COG2002	toxin-antitoxin pair type II binding
ABC_RS00345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC_RS00345	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC_RS00360	COG0488	(ABC) transporter
ABC_RS00375	COG0084	hydrolase, TatD family'
ABC_RS00380	COG3584	3D domain protein
ABC_RS00380	COG3583	domain protein
ABC_RS00385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ABC_RS00390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABC_RS00400	COG4466	Protein conserved in bacteria
ABC_RS00410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ABC_RS00415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC_RS00420	COG0251	oxidation-reduction process
ABC_RS00425	COG2088	sporulation resulting in formation of a cellular spore
ABC_RS00430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABC_RS00435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC_RS00440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABC_RS00445	COG0193	aminoacyl-tRNA hydrolase activity
ABC_RS00455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABC_RS00460	COG2002	toxin-antitoxin pair type II binding
ABC_RS00470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABC_RS00480	COG2244	polysaccharide biosynthetic process
ABC_RS00485	COG3956	TIGRFAM MazG family protein
ABC_RS00490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ABC_RS00495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABC_RS00500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC_RS00505	COG1247	-acetyltransferase
ABC_RS00510	COG0492	ferredoxin-NADP+ reductase activity
ABC_RS00535	COG1098	S1 RNA binding domain
ABC_RS00545	COG2851	Citrate transporter
ABC_RS00550	COG2208	phosphoserine phosphatase activity
ABC_RS00555	COG2304	oxidoreductase activity
ABC_RS00560	COG0515	serine threonine protein kinase
ABC_RS00565	COG0037	tRNA processing
ABC_RS00570	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABC_RS00575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC_RS00580	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABC_RS00585	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABC_RS00590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC_RS00595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABC_RS00600	COG0512	Glutamine amidotransferase of anthranilate synthase
ABC_RS00605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC_RS00610	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABC_RS00615	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ABC_RS00620	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABC_RS00625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABC_RS00630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABC_RS00715	COG3880	PFAM UvrB UvrC protein
ABC_RS00720	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ABC_RS00725	COG0542	response to heat
ABC_RS00730	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABC_RS00735	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ABC_RS00740	COG4956	integral membrane protein (PIN domain superfamily)
ABC_RS00745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABC_RS00750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABC_RS00755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC_RS00760	COG1045	serine acetyltransferase
ABC_RS00765	COG0215	cysteine-tRNA ligase activity
ABC_RS00775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC_RS00780	COG3688	RNA-binding protein containing a PIN domain
ABC_RS00790	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC_RS00795	COG0250	Participates in transcription elongation, termination and antitermination
ABC_RS00800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABC_RS00805	COG0081	regulation of translation
ABC_RS00810	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABC_RS00815	COG0222	ribosome binding
ABC_RS00820	COG2813	Specifically methylates the guanine in position
ABC_RS00825	COG0085	RNA polymerase activity
ABC_RS00830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABC_RS00835	COG1358	cellular component organization or biogenesis
ABC_RS00840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABC_RS00845	COG0049	tRNA binding
ABC_RS00850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ABC_RS00855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABC_RS00860	COG0051	transcription antitermination factor activity, RNA binding
ABC_RS00865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABC_RS00870	COG0088	Forms part of the polypeptide exit tunnel
ABC_RS00875	COG0089	rRNA binding
ABC_RS00880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABC_RS00885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABC_RS00890	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABC_RS00895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABC_RS00900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABC_RS00905	COG0255	Belongs to the universal ribosomal protein uL29 family
ABC_RS00910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABC_RS00915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABC_RS00920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABC_RS00925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ABC_RS00930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC_RS00935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABC_RS00940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABC_RS00945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABC_RS00950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABC_RS00955	COG1841	ribosomal large subunit assembly
ABC_RS00960	COG0200	Binds to the 23S rRNA
ABC_RS00965	COG0201	protein transport
ABC_RS00970	COG0563	adenylate kinase activity
ABC_RS00975	COG0024	Methionine aminopeptidase
ABC_RS00980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABC_RS00985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABC_RS00990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABC_RS00995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABC_RS01000	COG0202	RNA polymerase activity
ABC_RS01005	COG0203	ribosomal protein L17
ABC_RS01010	COG1122	ATPase activity
ABC_RS01020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC_RS01025	COG0101	tRNA pseudouridine synthase activity
ABC_RS01030	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABC_RS01035	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABC_RS01055	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ABC_RS01075	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC_RS01080	COG3711	transcriptional antiterminator
ABC_RS01085	COG1263	PTS System
ABC_RS01085	COG2190	(PTS) system
ABC_RS01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS01090	COG0489	protein tyrosine kinase activity
ABC_RS01125	COG0726	polysaccharide deacetylase
ABC_RS01165	COG2226	methyltransferase
ABC_RS01190	COG0789	Transcriptional regulator
ABC_RS01235	COG3181	Tripartite tricarboxylate transporter family receptor
ABC_RS01245	COG1454	alcohol dehydrogenase
ABC_RS01250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC_RS01260	COG2217	Heavy metal translocating P-type atpase
ABC_RS01270	COG1999	signal sequence binding
ABC_RS01295	COG4172	Belongs to the ABC transporter superfamily
ABC_RS01305	COG0601	transmembrane transport
ABC_RS01310	COG0747	negative chemotaxis
ABC_RS01315	COG1063	alcohol dehydrogenase
ABC_RS01320	COG2755	lipolytic protein G-D-S-L family
ABC_RS01325	COG0747	negative chemotaxis
ABC_RS01375	COG1595	DNA-templated transcription, initiation
ABC_RS01380	COG5662	AntiSigma factor
ABC_RS01385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ABC_RS01395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC_RS01410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABC_RS01415	COG1917	Cupin 2, conserved barrel domain protein
ABC_RS01415	COG2207	Transcriptional regulator
ABC_RS01425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABC_RS01435	COG1396	sequence-specific DNA binding
ABC_RS01440	COG1819	glycosyl
ABC_RS01445	COG1136	(ABC) transporter
ABC_RS01450	COG0577	efflux transmembrane transporter activity
ABC_RS01455	COG0745	RESPONSE REGULATOR receiver
ABC_RS01465	COG1309	transcriptional regulator
ABC_RS01470	COG2814	Major facilitator Superfamily
ABC_RS01480	COG1136	(ABC) transporter
ABC_RS01500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABC_RS01535	COG2072	flavoprotein involved in K transport
ABC_RS01550	COG2226	methyltransferase
ABC_RS01555	COG0180	Tryptophanyl-tRNA synthetase
ABC_RS01565	COG0697	spore germination
ABC_RS01590	COG1051	belongs to the nudix hydrolase family
ABC_RS01600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC_RS01605	COG0569	domain protein
ABC_RS01610	COG2267	carboxylic ester hydrolase activity
ABC_RS01615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ABC_RS01630	COG1528	Iron-storage protein
ABC_RS01635	COG0628	permease
ABC_RS01640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABC_RS01640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABC_RS01690	COG1609	Transcriptional regulator
ABC_RS01695	COG0789	Transcriptional regulator
ABC_RS01700	COG1132	(ABC) transporter
ABC_RS01705	COG1737	Transcriptional regulator
ABC_RS01710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC_RS01730	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ABC_RS01735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS01735	COG1263	PTS System
ABC_RS01745	COG1609	Transcriptional regulator
ABC_RS01750	COG2723	6-phospho-beta-galactosidase activity
ABC_RS01755	COG1940	carbohydrate kinase activity
ABC_RS01760	COG1175	transmembrane transport
ABC_RS01765	COG0395	ABC-type sugar transport system, permease component
ABC_RS01790	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
ABC_RS01810	COG3829	transcription factor binding
ABC_RS01810	COG3290	protein histidine kinase activity
ABC_RS01815	COG1454	alcohol dehydrogenase
ABC_RS01820	COG2610	gluconate transmembrane transporter activity
ABC_RS01825	COG2066	Belongs to the glutaminase family
ABC_RS01830	COG1454	alcohol dehydrogenase
ABC_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS01840	COG0697	spore germination
ABC_RS01850	COG0456	acetyltransferase
ABC_RS01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC_RS01860	COG1917	Cupin 2, conserved barrel domain protein
ABC_RS01875	COG1175	transmembrane transport
ABC_RS01880	COG0395	ABC-type sugar transport system, permease component
ABC_RS01885	COG3842	ATPase activity
ABC_RS01895	COG0318	PFAM AMP-dependent synthetase and ligase
ABC_RS01900	COG0318	PFAM AMP-dependent synthetase and ligase
ABC_RS01905	COG0183	Belongs to the thiolase family
ABC_RS01910	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS01920	COG2814	Major facilitator Superfamily
ABC_RS01925	COG1959	2 iron, 2 sulfur cluster binding
ABC_RS01930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABC_RS01930	COG1017	nitric oxide dioxygenase activity
ABC_RS01935	COG0584	glycerophosphoryl diester phosphodiesterase
ABC_RS01940	COG3842	ATPase activity
ABC_RS01945	COG1175	transmembrane transport
ABC_RS01950	COG0395	ABC-type sugar transport system, permease component
ABC_RS01955	COG1653	transport
ABC_RS01960	COG0584	glycerophosphoryl diester phosphodiesterase
ABC_RS01980	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ABC_RS01985	COG4209	transmembrane transport
ABC_RS01990	COG0395	ABC-type sugar transport system, permease component
ABC_RS02005	COG0673	inositol 2-dehydrogenase activity
ABC_RS02010	COG0726	polysaccharide deacetylase
ABC_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS02035	COG0010	Belongs to the arginase family
ABC_RS02050	COG1070	Carbohydrate kinase
ABC_RS02050	COG4806	L-rhamnose isomerase
ABC_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS02055	COG3347	Dehydrogenase
ABC_RS02060	COG3254	rhamnose metabolic process
ABC_RS02065	COG2814	Major facilitator Superfamily
ABC_RS02070	COG1917	Cupin 2, conserved barrel domain protein
ABC_RS02070	COG4977	sequence-specific DNA binding
ABC_RS02075	COG0673	inositol 2-dehydrogenase activity
ABC_RS02095	COG2972	Histidine kinase
ABC_RS02100	COG4753	response regulator
ABC_RS02100	COG2207	Transcriptional regulator
ABC_RS02105	COG1653	transport
ABC_RS02110	COG1175	transmembrane transport
ABC_RS02115	COG0395	ABC-type sugar transport system, permease component
ABC_RS02125	COG5002	protein histidine kinase activity
ABC_RS02130	COG0745	RESPONSE REGULATOR receiver
ABC_RS02135	COG0583	DNA-binding transcription factor activity
ABC_RS02150	COG3401	FG-GAP repeat protein
ABC_RS02160	COG1175	transmembrane transport
ABC_RS02165	COG0395	ABC-type sugar transport system, permease component
ABC_RS02180	COG1175	transmembrane transport
ABC_RS02185	COG0395	ABC-type sugar transport system, permease component
ABC_RS02190	COG5578	integral membrane protein
ABC_RS02200	COG2207	Transcriptional regulator
ABC_RS02205	COG0647	UMP catabolic process
ABC_RS02210	COG0371	Dehydrogenase
ABC_RS02220	COG1069	ribulokinase activity
ABC_RS02225	COG2160	L-arabinose isomerase activity
ABC_RS02230	COG4213	ABC transporter substrate-binding protein
ABC_RS02235	COG1129	ABC transporter
ABC_RS02240	COG4214	carbohydrate transport
ABC_RS02245	COG1486	melibiose metabolic process
ABC_RS02270	COG3279	Response regulator of the LytR AlgR family
ABC_RS02275	COG2076	Multidrug Resistance protein
ABC_RS02280	COG2076	Multidrug Resistance protein
ABC_RS02285	COG1309	transcriptional regulator
ABC_RS02290	COG2814	Major facilitator Superfamily
ABC_RS02295	COG1349	DNA-binding transcription factor activity
ABC_RS02300	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS02305	COG3718	enzyme involved in inositol metabolism
ABC_RS02310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC_RS02315	COG3962	Belongs to the TPP enzyme family
ABC_RS02320	COG1082	Xylose isomerase domain protein TIM barrel
ABC_RS02325	COG0673	inositol 2-dehydrogenase activity
ABC_RS02330	COG0191	fructose-bisphosphate aldolase activity
ABC_RS02335	COG0673	inositol 2-dehydrogenase activity
ABC_RS02340	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC_RS02345	COG2323	membrane
ABC_RS02350	COG2873	o-acetylhomoserine
ABC_RS02365	COG1175	transmembrane transport
ABC_RS02370	COG1653	transport
ABC_RS02380	COG1063	alcohol dehydrogenase
ABC_RS02385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC_RS02395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC_RS02400	COG2721	sulfolactate sulfo-lyase activity
ABC_RS02405	COG0246	Mannitol dehydrogenase
ABC_RS02410	COG3711	transcriptional antiterminator
ABC_RS02415	COG0191	fructose-bisphosphate aldolase activity
ABC_RS02420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS02420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS02420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS02425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS02430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS02430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS02435	COG1917	Cupin 2, conserved barrel domain protein
ABC_RS02445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS02450	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ABC_RS02455	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABC_RS02460	COG3829	transcription factor binding
ABC_RS02460	COG3290	protein histidine kinase activity
ABC_RS02475	COG2851	Citrate transporter
ABC_RS02480	COG0840	transmembrane signaling receptor activity
ABC_RS02525	COG1312	Catalyzes the dehydration of D-mannonate
ABC_RS02545	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS02550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC_RS02555	COG2186	Transcriptional regulator
ABC_RS02565	COG0457	Tetratricopeptide repeat
ABC_RS02565	COG0463	Glycosyl transferase, family 2
ABC_RS02575	COG2807	transmembrane transport
ABC_RS02590	COG1357	PFAM Pentapeptide repeats (8 copies)
ABC_RS02595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC_RS02600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC_RS02605	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABC_RS02610	COG2723	6-phospho-beta-galactosidase activity
ABC_RS02615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS02615	COG3711	transcriptional antiterminator
ABC_RS02635	COG1388	LysM domain
ABC_RS02635	COG3584	3D domain protein
ABC_RS02645	COG2188	Transcriptional regulator
ABC_RS02650	COG4821	SIS domain
ABC_RS02660	COG3850	Histidine kinase
ABC_RS02660	COG5002	protein histidine kinase activity
ABC_RS02670	COG3212	peptidase
ABC_RS02685	COG0535	radical SAM domain protein
ABC_RS02690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC_RS02700	COG2226	methyltransferase
ABC_RS02730	COG0438	transferase activity, transferring glycosyl groups
ABC_RS02780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABC_RS02785	COG2755	lipolytic protein G-D-S-L family
ABC_RS02795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC_RS02805	COG4948	Mandelate Racemase Muconate Lactonizing
ABC_RS02825	COG2205	protein histidine kinase activity
ABC_RS02830	COG0745	RESPONSE REGULATOR receiver
ABC_RS02845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC_RS02855	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABC_RS02865	COG0710	3-dehydroquinate dehydratase activity
ABC_RS02905	COG4145	pantothenate transmembrane transporter activity
ABC_RS02915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABC_RS02920	COG2186	Transcriptional regulator
ABC_RS02925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC_RS02935	COG1473	amidohydrolase
ABC_RS02940	COG1464	Belongs to the NlpA lipoprotein family
ABC_RS02945	COG2011	ABC-type metal ion transport system permease component
ABC_RS02950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC_RS02955	COG0662	Cupin 2, conserved barrel domain protein
ABC_RS02955	COG2207	Transcriptional regulator
ABC_RS02960	COG3507	Belongs to the glycosyl hydrolase 43 family
ABC_RS02970	COG4209	transmembrane transport
ABC_RS02975	COG0395	ABC-type sugar transport system, permease component
ABC_RS03000	COG1228	amidohydrolase
ABC_RS03005	COG1228	amidohydrolase
ABC_RS03010	COG0747	negative chemotaxis
ABC_RS03020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS03025	COG0444	Belongs to the ABC transporter superfamily
ABC_RS03030	COG4608	Belongs to the ABC transporter superfamily
ABC_RS03040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC_RS03045	COG1414	Transcriptional regulator
ABC_RS03050	COG2115	Belongs to the xylose isomerase family
ABC_RS03055	COG1070	Carbohydrate kinase
ABC_RS03065	COG1940	carbohydrate kinase activity
ABC_RS03075	COG0673	inositol 2-dehydrogenase activity
ABC_RS03080	COG2508	Transcriptional regulator
ABC_RS03105	COG4126	flavin adenine dinucleotide binding
ABC_RS03115	COG0477	Major facilitator Superfamily
ABC_RS03120	COG1942	4-Oxalocrotonate Tautomerase
ABC_RS03135	COG0318	PFAM AMP-dependent synthetase and ligase
ABC_RS03160	COG2258	MOSC domain
ABC_RS03170	COG0431	NADPH-dependent FMN reductase
ABC_RS03175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC_RS03180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC_RS03185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC_RS03190	COG1116	anion transmembrane transporter activity
ABC_RS03205	COG1802	Transcriptional regulator
ABC_RS03225	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC_RS03235	COG0175	sulfate reduction
ABC_RS03240	COG2046	Belongs to the sulfate adenylyltransferase family
ABC_RS03245	COG0306	phosphate transporter
ABC_RS03250	COG0529	Catalyzes the synthesis of activated sulfate
ABC_RS03255	COG1587	Uroporphyrinogen-III synthase
ABC_RS03255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC_RS03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABC_RS03275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABC_RS03285	COG1131	(ABC) transporter
ABC_RS03290	COG2188	Transcriptional regulator
ABC_RS03315	COG0583	DNA-binding transcription factor activity
ABC_RS03320	COG0473	3-isopropylmalate dehydrogenase activity
ABC_RS03325	COG1053	succinate dehydrogenase
ABC_RS03330	COG1063	alcohol dehydrogenase
ABC_RS03335	COG1312	Catalyzes the dehydration of D-mannonate
ABC_RS03340	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS03345	COG0163	prenyltransferase activity
ABC_RS03355	COG2814	Major facilitator Superfamily
ABC_RS03360	COG0798	PFAM Bile acid sodium symporter
ABC_RS03370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABC_RS03380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC_RS03385	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABC_RS03390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC_RS03395	COG1486	melibiose metabolic process
ABC_RS03400	COG3394	polysaccharide catabolic process
ABC_RS03405	COG2188	Transcriptional regulator
ABC_RS03420	COG5294	Protein conserved in bacteria
ABC_RS03425	COG2271	Major facilitator Superfamily
ABC_RS03430	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC_RS03435	COG3844	kynureninase activity
ABC_RS03470	COG0697	spore germination
ABC_RS03475	COG1349	DNA-binding transcription factor activity
ABC_RS03480	COG3395	kinase activity
ABC_RS03485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABC_RS03490	COG2610	gluconate transmembrane transporter activity
ABC_RS03515	COG2851	Citrate transporter
ABC_RS03520	COG4565	transcriptional regulatory protein
ABC_RS03525	COG3290	protein histidine kinase activity
ABC_RS03530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC_RS03535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABC_RS03565	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ABC_RS03570	COG0626	cystathionine gamma-synthase activity
ABC_RS03575	COG3457	Alanine racemase
ABC_RS03580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ABC_RS03585	COG2214	Heat shock protein DnaJ domain protein
ABC_RS03590	COG0443	Heat shock 70 kDa protein
ABC_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS03600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC_RS03605	COG1119	ATPase activity
ABC_RS03620	COG1175	transmembrane transport
ABC_RS03625	COG0395	ABC-type sugar transport system, permease component
ABC_RS03630	COG4842	Belongs to the WXG100 family
ABC_RS03640	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABC_RS03645	COG1674	ftsk spoiiie
ABC_RS03650	COG1511	domain protein
ABC_RS03725	COG1136	(ABC) transporter
ABC_RS03745	COG1737	Transcriptional regulator
ABC_RS03750	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ABC_RS03755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS03755	COG1263	PTS System
ABC_RS03755	COG2190	(PTS) system
ABC_RS03760	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC_RS03765	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ABC_RS03770	COG1140	nitrate reductase beta subunit
ABC_RS03780	COG2181	nitrate reductase activity
ABC_RS03795	COG2197	response regulator
ABC_RS03800	COG2223	nitrite transmembrane transporter activity
ABC_RS03815	COG2972	Histidine kinase
ABC_RS03820	COG4753	response regulator
ABC_RS03820	COG2207	Transcriptional regulator
ABC_RS03825	COG4209	transmembrane transport
ABC_RS03830	COG0395	ABC-type sugar transport system, permease component
ABC_RS03840	COG1191	sigma factor activity
ABC_RS03845	COG0586	Pfam SNARE associated Golgi protein
ABC_RS03850	COG1486	melibiose metabolic process
ABC_RS03855	COG2207	Transcriptional regulator
ABC_RS03860	COG3239	Fatty acid desaturase
ABC_RS03865	COG4585	Histidine kinase
ABC_RS03870	COG2197	response regulator
ABC_RS03875	COG2239	Acts as a magnesium transporter
ABC_RS03885	COG1846	Transcriptional regulator
ABC_RS03900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS03905	COG0456	acetyltransferase
ABC_RS03910	COG0024	Methionine aminopeptidase
ABC_RS03925	COG1929	Belongs to the glycerate kinase type-1 family
ABC_RS03945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABC_RS03955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABC_RS03960	COG1404	Belongs to the peptidase S8 family
ABC_RS03975	COG2818	Glycosylase
ABC_RS03980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABC_RS03990	COG0861	Integral membrane protein TerC family
ABC_RS03995	COG0596	Alpha beta hydrolase
ABC_RS04000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABC_RS04005	COG1404	Belongs to the peptidase S8 family
ABC_RS04015	COG1876	peptidase activity
ABC_RS04020	COG0531	amino acid
ABC_RS04030	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ABC_RS04030	COG2508	Transcriptional regulator
ABC_RS04035	COG0686	Belongs to the AlaDH PNT family
ABC_RS04040	COG2706	6-phosphogluconolactonase activity
ABC_RS04045	COG2962	Rard protein
ABC_RS04055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC_RS04060	COG0765	amino acid transport
ABC_RS04065	COG0765	amino acid transport
ABC_RS04070	COG0784	Response regulator, receiver
ABC_RS04075	COG4191	Histidine kinase
ABC_RS04080	COG2362	D-Aminopeptidase
ABC_RS04085	COG0601	transmembrane transport
ABC_RS04090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS04095	COG0444	Belongs to the ABC transporter superfamily
ABC_RS04100	COG4166	transmembrane transport
ABC_RS04105	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC_RS04110	COG0791	NLP P60 protein
ABC_RS04115	COG4608	Belongs to the ABC transporter superfamily
ABC_RS04120	COG1733	regulation of RNA biosynthetic process
ABC_RS04130	COG2205	protein histidine kinase activity
ABC_RS04135	COG2111	Na H antiporter
ABC_RS04135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC_RS04140	COG2111	Na H antiporter
ABC_RS04145	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC_RS04150	COG0651	ATP synthesis coupled electron transport
ABC_RS04155	COG1863	multisubunit Na H antiporter MnhE subunit
ABC_RS04160	COG2212	antiporter activity
ABC_RS04165	COG1320	monovalent cation:proton antiporter activity
ABC_RS04175	COG1082	Xylose isomerase domain protein TIM barrel
ABC_RS04180	COG0673	inositol 2-dehydrogenase activity
ABC_RS04190	COG3214	Protein conserved in bacteria
ABC_RS04195	COG5578	integral membrane protein
ABC_RS04205	COG1876	peptidase activity
ABC_RS04210	COG1368	sulfuric ester hydrolase activity
ABC_RS04220	COG0705	Rhomboid family
ABC_RS04225	COG0736	holo-[acyl-carrier-protein] synthase activity
ABC_RS04230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABC_RS04235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABC_RS04240	COG0864	Transcriptional regulator
ABC_RS04245	COG2337	Toxic component of a toxin-antitoxin (TA) module
ABC_RS04250	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC_RS04255	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC_RS04260	COG2172	sigma factor antagonist activity
ABC_RS04265	COG2208	phosphoserine phosphatase activity
ABC_RS04270	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC_RS04275	COG2172	sigma factor antagonist activity
ABC_RS04280	COG1191	sigma factor activity
ABC_RS04290	COG2183	response to ionizing radiation
ABC_RS04295	COG3091	SprT-like family
ABC_RS04360	COG3328	transposase activity
ABC_RS04370	COG4282	regulation of fungal-type cell wall biogenesis
ABC_RS04380	COG0662	Cupin 2, conserved barrel domain protein
ABC_RS04385	COG2816	NAD+ diphosphatase activity
ABC_RS04405	COG1278	Cold shock
ABC_RS04410	COG1329	Transcriptional regulator
ABC_RS04415	COG0640	Transcriptional regulator
ABC_RS04420	COG0346	lactoylglutathione lyase activity
ABC_RS04425	COG0640	Transcriptional regulator
ABC_RS04430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABC_RS04435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABC_RS04445	COG2140	Oxalate decarboxylase
ABC_RS04450	COG2514	catechol 2,3-dioxygenase activity
ABC_RS04455	COG1802	Transcriptional regulator
ABC_RS04460	COG0473	3-isopropylmalate dehydrogenase activity
ABC_RS04500	COG5646	InterPro IPR014922
ABC_RS04505	COG1687	branched-chain amino acid
ABC_RS04510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABC_RS04535	COG0384	phenazine biosynthesis protein PhzF
ABC_RS04540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS04540	COG3711	transcriptional antiterminator
ABC_RS04550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS04550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS04550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS04620	COG1285	pathogenesis
ABC_RS04625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC_RS04630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABC_RS04635	COG0626	cystathionine gamma-synthase activity
ABC_RS04645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABC_RS04650	COG0802	atpase or kinase
ABC_RS04655	COG1214	PFAM Peptidase M22, glycoprotease
ABC_RS04660	COG0456	acetyltransferase
ABC_RS04665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABC_RS04670	COG0488	(ABC) transporter
ABC_RS04675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ABC_RS04680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABC_RS04685	COG0805	protein transport
ABC_RS04690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC_RS04695	COG2011	ABC-type metal ion transport system permease component
ABC_RS04700	COG1464	Belongs to the NlpA lipoprotein family
ABC_RS04705	COG0371	Dehydrogenase
ABC_RS04715	COG1266	CAAX protease self-immunity
ABC_RS04720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ABC_RS04725	COG0459	protein refolding
ABC_RS04750	COG4821	SIS domain
ABC_RS04755	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ABC_RS04760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC_RS04765	COG2368	4-hydroxyphenylacetate
ABC_RS04770	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC_RS04785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABC_RS04790	COG0303	'Molybdopterin
ABC_RS04795	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABC_RS04800	COG0314	molybdopterin synthase activity
ABC_RS04805	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ABC_RS04810	COG2116	formate transmembrane transporter activity
ABC_RS04815	COG3383	formate dehydrogenase (NAD+) activity
ABC_RS04825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABC_RS04840	COG4485	Bacterial membrane protein, YfhO
ABC_RS04850	COG0463	Glycosyl transferase, family 2
ABC_RS04870	COG0765	amino acid transport
ABC_RS04875	COG0765	amino acid transport
ABC_RS04880	COG1126	abc transporter atp-binding protein
ABC_RS04885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABC_RS04890	COG3290	protein histidine kinase activity
ABC_RS04895	COG4565	transcriptional regulatory protein
ABC_RS04900	COG3493	citrate carrier protein
ABC_RS04905	COG0281	malic enzyme
ABC_RS04940	COG4824	toxin secretion phage lysis holin
ABC_RS04950	COG0778	Nitroreductase
ABC_RS04955	COG0768	penicillin binding
ABC_RS04965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABC_RS04975	COG0714	Associated with various cellular activities
ABC_RS04980	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ABC_RS04985	COG1305	Transglutaminase-like
ABC_RS04990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABC_RS04990	COG0519	Catalyzes the synthesis of GMP from XMP
ABC_RS05025	COG1136	(ABC) transporter
ABC_RS05030	COG0577	efflux transmembrane transporter activity
ABC_RS05035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS05050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC_RS05055	COG2814	Major facilitator Superfamily
ABC_RS05060	COG1846	Transcriptional regulator
ABC_RS05070	COG2376	Dihydroxyacetone kinase
ABC_RS05080	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ABC_RS05105	COG2252	PERMEase
ABC_RS05120	COG1408	metallophosphoesterase
ABC_RS05130	COG3290	protein histidine kinase activity
ABC_RS05130	COG3829	transcription factor binding
ABC_RS05135	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS05140	COG0737	Belongs to the 5'-nucleotidase family
ABC_RS05145	COG1476	TRANSCRIPTIONal
ABC_RS05155	COG1335	isochorismatase
ABC_RS05160	COG0326	Molecular chaperone. Has ATPase activity
ABC_RS05165	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ABC_RS05170	COG2124	cytochrome p450
ABC_RS05180	COG1620	l-lactate permease
ABC_RS05185	COG0247	lactate metabolic process
ABC_RS05190	COG1139	Iron-sulfur cluster binding protein
ABC_RS05195	COG1556	Lactate utilization protein
ABC_RS05200	COG2186	Transcriptional regulator
ABC_RS05205	COG1454	alcohol dehydrogenase
ABC_RS05210	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS05215	COG1510	regulation of RNA biosynthetic process
ABC_RS05235	COG3764	Sortase (surface protein transpeptidase)
ABC_RS05250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC_RS05255	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ABC_RS05260	COG2059	Chromate
ABC_RS05265	COG2059	Chromate
ABC_RS05270	COG1349	DNA-binding transcription factor activity
ABC_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS05280	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ABC_RS05285	COG1904	glucuronate isomerase
ABC_RS05290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC_RS05295	COG0789	Transcriptional regulator
ABC_RS05300	COG3424	synthase
ABC_RS05305	COG1755	Isoprenylcysteine carboxyl methyltransferase
ABC_RS05330	COG1132	(ABC) transporter
ABC_RS05335	COG1132	(ABC) transporter
ABC_RS05355	COG1191	sigma factor activity
ABC_RS05365	COG0025	NhaP-type Na H and K H
ABC_RS05370	COG3290	protein histidine kinase activity
ABC_RS05375	COG4565	transcriptional regulatory protein
ABC_RS05400	COG3654	unkown
ABC_RS05435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABC_RS05440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABC_RS05445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC_RS05450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABC_RS05455	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC_RS05460	COG0047	phosphoribosylformylglycinamidine synthase activity
ABC_RS05465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABC_RS05470	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABC_RS05475	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABC_RS05480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABC_RS05485	COG0138	bifunctional purine biosynthesis protein purh
ABC_RS05490	COG0151	Belongs to the GarS family
ABC_RS05500	COG1609	Transcriptional regulator
ABC_RS05505	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS05510	COG1063	alcohol dehydrogenase
ABC_RS05520	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS05540	COG2197	response regulator
ABC_RS05545	COG1131	(ABC) transporter
ABC_RS05665	COG1510	regulation of RNA biosynthetic process
ABC_RS05685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABC_RS05695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABC_RS05700	COG4496	protein, YerC YecD
ABC_RS05705	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABC_RS05725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC_RS05730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC_RS05735	COG1120	ATPase activity
ABC_RS05740	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ABC_RS05745	COG0210	DNA helicase
ABC_RS05750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABC_RS05755	COG4851	CamS sex pheromone cAM373 precursor
ABC_RS05760	COG1744	ABC transporter substrate-binding protein PnrA-like
ABC_RS05765	COG3845	ABC transporter
ABC_RS05770	COG4603	Belongs to the binding-protein-dependent transport system permease family
ABC_RS05775	COG1079	Belongs to the binding-protein-dependent transport system permease family
ABC_RS05790	COG2318	DinB family
ABC_RS05795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC_RS05800	COG0154	amidase activity
ABC_RS05805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABC_RS05810	COG1597	lipid kinase activity
ABC_RS05815	COG0716	FMN binding
ABC_RS05820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC_RS05830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS05855	COG0789	Transcriptional regulator
ABC_RS05865	COG0129	dihydroxy-acid dehydratase activity
ABC_RS05870	COG1414	Transcriptional regulator
ABC_RS05880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC_RS05885	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS05890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC_RS05895	COG1121	(ABC) transporter
ABC_RS05900	COG3443	Belongs to the bacterial solute-binding protein 9 family
ABC_RS05900	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC_RS05905	COG3443	Belongs to the bacterial solute-binding protein 9 family
ABC_RS05910	COG0523	cobalamin synthesis protein
ABC_RS05920	COG3340	Belongs to the peptidase S51 family
ABC_RS05925	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC_RS05930	COG2207	Transcriptional regulator
ABC_RS05935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC_RS05955	COG2721	sulfolactate sulfo-lyase activity
ABC_RS05960	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABC_RS05965	COG1846	Transcriptional regulator
ABC_RS05965	COG1940	carbohydrate kinase activity
ABC_RS05975	COG1501	Belongs to the glycosyl hydrolase 31 family
ABC_RS05980	COG2972	Histidine kinase
ABC_RS05985	COG4753	response regulator
ABC_RS05985	COG2207	Transcriptional regulator
ABC_RS05990	COG4209	transmembrane transport
ABC_RS05995	COG0395	ABC-type sugar transport system, permease component
ABC_RS06010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABC_RS06020	COG3250	beta-galactosidase activity
ABC_RS06020	COG5297	Belongs to the glycosyl hydrolase family 6
ABC_RS06030	COG2207	Transcriptional regulator
ABC_RS06035	COG1653	transport
ABC_RS06040	COG4209	transmembrane transport
ABC_RS06045	COG0395	ABC-type sugar transport system, permease component
ABC_RS06060	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ABC_RS06070	COG5578	integral membrane protein
ABC_RS06075	COG0673	inositol 2-dehydrogenase activity
ABC_RS06080	COG2721	sulfolactate sulfo-lyase activity
ABC_RS06085	COG0246	Mannitol dehydrogenase
ABC_RS06105	COG3732	PTS system glucitol sorbitol-specific
ABC_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS06120	COG3397	chitin binding
ABC_RS06130	COG3328	transposase activity
ABC_RS06135	COG3764	Sortase (surface protein transpeptidase)
ABC_RS06145	COG2610	gluconate transmembrane transporter activity
ABC_RS06155	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC_RS06160	COG0745	RESPONSE REGULATOR receiver
ABC_RS06165	COG2205	protein histidine kinase activity
ABC_RS06170	COG1131	(ABC) transporter
ABC_RS06180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC_RS06185	COG0640	Transcriptional regulator
ABC_RS06190	COG1686	Belongs to the peptidase S11 family
ABC_RS06205	COG0010	Belongs to the arginase family
ABC_RS06220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC_RS06225	COG2423	ornithine cyclodeaminase activity
ABC_RS06230	COG5577	PFAM Coat F domain
ABC_RS06235	COG1113	amino acid transport
ABC_RS06240	COG1280	lysine exporter protein (LysE YggA)
ABC_RS06320	COG3011	Protein conserved in bacteria
ABC_RS06325	COG2318	DinB family
ABC_RS06330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS06335	COG1279	arginine transmembrane transporter activity
ABC_RS06340	COG1522	sequence-specific DNA binding
ABC_RS06350	COG3328	transposase activity
ABC_RS06375	COG1131	(ABC) transporter
ABC_RS06395	COG1175	transmembrane transport
ABC_RS06400	COG0395	ABC-type sugar transport system, permease component
ABC_RS06415	COG1396	sequence-specific DNA binding
ABC_RS06425	COG0747	negative chemotaxis
ABC_RS06435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC_RS06440	COG0385	Bile acid
ABC_RS06445	COG0277	FAD linked oxidase domain protein
ABC_RS06450	COG5002	protein histidine kinase activity
ABC_RS06455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABC_RS06460	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABC_RS06470	COG4208	sulfate ABC transporter
ABC_RS06485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC_RS06490	COG4120	Belongs to the binding-protein-dependent transport system permease family
ABC_RS06500	COG2391	methyltransferase activity
ABC_RS06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABC_RS06520	COG0444	Belongs to the ABC transporter superfamily
ABC_RS06525	COG4608	Belongs to the ABC transporter superfamily
ABC_RS06530	COG0747	negative chemotaxis
ABC_RS06535	COG0601	transmembrane transport
ABC_RS06540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS06565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABC_RS06570	COG3639	organic phosphonate transmembrane transporter activity
ABC_RS06575	COG3639	organic phosphonate transmembrane transporter activity
ABC_RS06580	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ABC_RS06590	COG3973	AAA domain
ABC_RS06595	COG1132	(ABC) transporter
ABC_RS06600	COG1132	(ABC) transporter
ABC_RS06615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABC_RS06620	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ABC_RS06625	COG1115	amino acid carrier protein
ABC_RS06630	COG2244	polysaccharide biosynthetic process
ABC_RS06635	COG1649	PFAM Uncharacterised BCR, COG1649
ABC_RS06645	COG1263	PTS System
ABC_RS06645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS06650	COG0366	Alpha amylase catalytic
ABC_RS06655	COG2188	Transcriptional regulator
ABC_RS06665	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ABC_RS06670	COG0488	(ABC) transporter
ABC_RS06675	COG1349	DNA-binding transcription factor activity
ABC_RS06680	COG1105	Belongs to the carbohydrate kinase PfkB family
ABC_RS06685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS06685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS06685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS06690	COG1077	Cell shape determining protein MreB Mrl
ABC_RS06695	COG0733	neurotransmitter:sodium symporter activity
ABC_RS06705	COG2002	toxin-antitoxin pair type II binding
ABC_RS06715	COG0328	RNA-DNA hybrid ribonuclease activity
ABC_RS06715	COG3341	Caulimovirus viroplasmin
ABC_RS06720	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS06735	COG0753	catalase activity
ABC_RS06740	COG1164	Oligoendopeptidase f
ABC_RS06750	COG1294	oxidase, subunit
ABC_RS06755	COG1271	oxidase subunit
ABC_RS06770	COG0535	radical SAM domain protein
ABC_RS06780	COG1253	flavin adenine dinucleotide binding
ABC_RS06790	COG0726	polysaccharide deacetylase
ABC_RS06795	COG0445	tRNA wobble uridine modification
ABC_RS06815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABC_RS06820	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC_RS06830	COG1090	epimerase
ABC_RS06835	COG2137	regulation of response to DNA damage stimulus
ABC_RS06850	COG1988	membrane-bound metal-dependent
ABC_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS06885	COG3557	Belongs to the UPF0374 family
ABC_RS06890	COG1132	(ABC) transporter
ABC_RS06895	COG4129	membrane
ABC_RS06900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC_RS06905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABC_RS06910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC_RS06920	COG0735	belongs to the Fur family
ABC_RS07025	COG5434	Belongs to the glycosyl hydrolase 28 family
ABC_RS07035	COG4974	Belongs to the 'phage' integrase family
ABC_RS07140	COG5434	Belongs to the glycosyl hydrolase 28 family
ABC_RS07170	COG4824	toxin secretion phage lysis holin
ABC_RS07175	COG5632	N-Acetylmuramoyl-L-alanine amidase
ABC_RS07175	COG3409	Peptidoglycan-binding domain 1 protein
ABC_RS07310	COG0640	Transcriptional regulator
ABC_RS07315	COG2814	Major facilitator Superfamily
ABC_RS07320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABC_RS07330	COG1846	Transcriptional regulator
ABC_RS07340	COG0596	Alpha beta hydrolase
ABC_RS07350	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC_RS07360	COG1959	2 iron, 2 sulfur cluster binding
ABC_RS07365	COG0477	Major facilitator Superfamily
ABC_RS07380	COG0789	Transcriptional regulator
ABC_RS07385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABC_RS07410	COG3328	transposase activity
ABC_RS07415	COG0210	DNA helicase
ABC_RS07435	COG3964	amidohydrolase
ABC_RS07505	COG2267	carboxylic ester hydrolase activity
ABC_RS07530	COG1733	regulation of RNA biosynthetic process
ABC_RS07535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABC_RS07555	COG4585	Histidine kinase
ABC_RS07560	COG2197	response regulator
ABC_RS07565	COG1131	(ABC) transporter
ABC_RS07580	COG1442	glycosyl transferase family 8
ABC_RS07585	COG4894	glucomannan catabolic process
ABC_RS07595	COG0584	glycerophosphoryl diester phosphodiesterase
ABC_RS07610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC_RS07620	COG0737	Belongs to the 5'-nucleotidase family
ABC_RS07630	COG3012	SEC-C Motif Domain Protein
ABC_RS07630	COG1405	negative regulation of cell septum assembly
ABC_RS07635	COG0471	metal ion transport
ABC_RS07645	COG1966	Carbon starvation protein
ABC_RS07655	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS07660	COG1263	PTS System
ABC_RS07660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS07670	COG1621	beta-fructofuranosidase activity
ABC_RS07675	COG1917	Cupin 2, conserved barrel domain protein
ABC_RS07675	COG2207	Transcriptional regulator
ABC_RS07685	COG1131	(ABC) transporter
ABC_RS07695	COG1725	Transcriptional regulator
ABC_RS07700	COG1131	(ABC) transporter
ABC_RS07710	COG1363	Peptidase, m42
ABC_RS07715	COG0783	Belongs to the Dps family
ABC_RS07730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC_RS07745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABC_RS07760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC_RS07765	COG2766	serine protein kinase
ABC_RS07780	COG2718	Belongs to the UPF0229 family
ABC_RS07790	COG2814	Major facilitator Superfamily
ABC_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS07830	COG2188	Transcriptional regulator
ABC_RS07835	COG0165	Argininosuccinate lyase
ABC_RS07840	COG2188	Transcriptional regulator
ABC_RS07845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ABC_RS07850	COG0363	glucosamine-6-phosphate deaminase activity
ABC_RS07860	COG0436	Aminotransferase
ABC_RS07865	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC_RS07870	COG0584	glycerophosphoryl diester phosphodiesterase
ABC_RS07875	COG0438	transferase activity, transferring glycosyl groups
ABC_RS07880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABC_RS07880	COG3153	acetyltransferase
ABC_RS07885	COG1489	DNA binding
ABC_RS07890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABC_RS07895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABC_RS07900	COG2719	SpoVR family
ABC_RS07905	COG1132	(ABC) transporter
ABC_RS07910	COG1132	(ABC) transporter
ABC_RS07915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS07925	COG1704	LemA family
ABC_RS07930	COG1960	acyl-CoA dehydrogenase activity
ABC_RS07935	COG0439	Biotin carboxylase
ABC_RS07940	COG0511	ligase activity, forming carbon-carbon bonds
ABC_RS07945	COG1024	Enoyl-CoA hydratase
ABC_RS07950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC_RS07965	COG3842	ATPase activity
ABC_RS07970	COG2508	Transcriptional regulator
ABC_RS07980	COG4399	Belongs to the UPF0754 family
ABC_RS07985	COG3679	Belongs to the UPF0342 family
ABC_RS07990	COG0561	phosphatase activity
ABC_RS08005	COG0745	RESPONSE REGULATOR receiver
ABC_RS08010	COG2205	protein histidine kinase activity
ABC_RS08010	COG2770	Histidine kinase
ABC_RS08015	COG3481	metal-dependent phosphohydrolase, HD sub domain
ABC_RS08025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABC_RS08040	COG1846	Transcriptional regulator
ABC_RS08050	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ABC_RS08055	COG0537	adenosine 5'-monophosphoramidase activity
ABC_RS08060	COG1131	(ABC) transporter
ABC_RS08065	COG4473	ABC transporter
ABC_RS08075	COG0785	Cytochrome C biogenesis protein
ABC_RS08080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC_RS08085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABC_RS08090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABC_RS08095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ABC_RS08105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABC_RS08110	COG4492	Belongs to the UPF0735 family
ABC_RS08115	COG0077	Prephenate dehydratase
ABC_RS08120	COG1827	regulation of RNA biosynthetic process
ABC_RS08125	COG1104	cysteine desulfurase activity
ABC_RS08130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABC_RS08135	COG0157	Belongs to the NadC ModD family
ABC_RS08140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABC_RS08165	COG0632	four-way junction helicase activity
ABC_RS08170	COG2255	four-way junction helicase activity
ABC_RS08180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC_RS08185	COG0343	queuine tRNA-ribosyltransferase activity
ABC_RS08190	COG1862	Preprotein translocase
ABC_RS08210	COG2244	polysaccharide biosynthetic process
ABC_RS08225	COG5416	Lipopolysaccharide assembly protein A domain
ABC_RS08230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABC_RS08230	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ABC_RS08235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABC_RS08240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABC_RS08245	COG1490	D-aminoacyl-tRNA deacylase activity
ABC_RS08250	COG1609	Transcriptional regulator
ABC_RS08260	COG0673	inositol 2-dehydrogenase activity
ABC_RS08265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABC_RS08270	COG0124	histidyl-tRNA synthetase
ABC_RS08275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABC_RS08290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABC_RS08295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABC_RS08305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABC_RS08310	COG1959	2 iron, 2 sulfur cluster binding
ABC_RS08315	COG1104	cysteine desulfurase activity
ABC_RS08320	COG0482	sulfurtransferase activity
ABC_RS08330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABC_RS08335	COG3881	PFAM PRC-barrel domain
ABC_RS08350	COG0628	permease
ABC_RS08355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABC_RS08360	COG4472	Bacterial protein of unknown function (DUF965)
ABC_RS08365	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABC_RS08370	COG3906	Belongs to the UPF0473 family
ABC_RS08375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABC_RS08380	COG4122	O-methyltransferase activity
ABC_RS08385	COG0572	uridine kinase
ABC_RS08390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABC_RS08400	COG3285	dna ligase
ABC_RS08400	COG1793	dna ligase
ABC_RS08405	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ABC_RS08410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABC_RS08425	COG0747	negative chemotaxis
ABC_RS08430	COG4608	Belongs to the ABC transporter superfamily
ABC_RS08435	COG0444	Belongs to the ABC transporter superfamily
ABC_RS08440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS08445	COG0601	transmembrane transport
ABC_RS08450	COG1309	transcriptional regulator
ABC_RS08465	COG0095	Lipoate-protein ligase
ABC_RS08470	COG1288	antiporter activity
ABC_RS08480	COG0385	Bile acid
ABC_RS08495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABC_RS08495	COG1587	Uroporphyrinogen-III synthase
ABC_RS08500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABC_RS08505	COG2146	nitrite reductase [NAD(P)H] activity
ABC_RS08510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABC_RS08515	COG0243	molybdopterin cofactor binding
ABC_RS08520	COG2223	nitrite transmembrane transporter activity
ABC_RS08525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC_RS08540	COG0776	regulation of translation
ABC_RS08545	COG1320	monovalent cation:proton antiporter activity
ABC_RS08550	COG2212	antiporter activity
ABC_RS08555	COG1863	multisubunit Na H antiporter MnhE subunit
ABC_RS08560	COG0651	ATP synthesis coupled electron transport
ABC_RS08565	COG1006	Multisubunit Na H antiporter MnhC subunit
ABC_RS08570	COG2111	Na H antiporter
ABC_RS08575	COG2111	Na H antiporter
ABC_RS08575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABC_RS08585	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ABC_RS08590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ABC_RS08595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABC_RS08600	COG1534	Rna-binding protein
ABC_RS08605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABC_RS08610	COG1713	HD superfamily hydrolase involved in NAD metabolism
ABC_RS08615	COG0799	negative regulation of ribosome biogenesis
ABC_RS08620	COG2996	Protein conserved in bacteria
ABC_RS08625	COG2226	methyltransferase
ABC_RS08630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABC_RS08635	COG1555	photosystem II stabilization
ABC_RS08635	COG1596	polysaccharide export
ABC_RS08640	COG2131	deaminase
ABC_RS08645	COG0658	competence protein
ABC_RS08645	COG2333	competence protein COMEC
ABC_RS08655	COG1466	dna polymerase III delta subunit
ABC_RS08660	COG0268	Binds directly to 16S ribosomal RNA
ABC_RS08665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ABC_RS08670	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC_RS08680	COG0481	GTPase activity
ABC_RS08685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABC_RS08690	COG1420	regulation of RNA biosynthetic process
ABC_RS08695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABC_RS08700	COG0443	Heat shock 70 kDa protein
ABC_RS08705	COG0484	heat shock protein binding
ABC_RS08710	COG2264	protein methyltransferase activity
ABC_RS08715	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABC_RS08720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC_RS08725	COG2226	methyltransferase
ABC_RS08730	COG1301	dicarboxylic acid transport
ABC_RS08735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ABC_RS08740	COG0667	Aldo Keto reductase
ABC_RS08745	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABC_RS08750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABC_RS08755	COG1610	YqeY-like protein
ABC_RS08760	COG1030	water channel activity
ABC_RS08765	COG4864	UPF0365 protein
ABC_RS08785	COG1702	phosphate starvation-inducible protein PhoH
ABC_RS08790	COG1480	7TM receptor with intracellular HD hydrolase
ABC_RS08795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ABC_RS08800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABC_RS08805	COG0295	cytidine deaminase activity
ABC_RS08810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABC_RS08815	COG1381	Involved in DNA repair and RecF pathway recombination
ABC_RS08825	COG0752	glycyl-tRNA synthetase alpha subunit
ABC_RS08830	COG0751	glycine-tRNA ligase activity
ABC_RS08835	COG0517	IMP dehydrogenase activity
ABC_RS08840	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABC_RS08845	COG1671	Belongs to the UPF0178 family
ABC_RS08850	COG0358	DNA primase activity
ABC_RS08855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABC_RS08860	COG2010	Cytochrome c
ABC_RS08865	COG2384	SAM-dependent methyltransferase
ABC_RS08870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABC_RS08875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ABC_RS08880	COG1329	Transcriptional regulator
ABC_RS08890	COG0513	Belongs to the DEAD box helicase family
ABC_RS08895	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABC_RS08905	COG5002	protein histidine kinase activity
ABC_RS08915	COG1121	(ABC) transporter
ABC_RS08920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC_RS08925	COG0735	belongs to the Fur family
ABC_RS08935	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ABC_RS08940	COG4709	membrane
ABC_RS08945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABC_RS08955	COG2814	Major facilitator Superfamily
ABC_RS08960	COG4086	secreted protein
ABC_RS08975	COG0704	Plays a role in the regulation of phosphate uptake
ABC_RS09005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC_RS09010	COG0477	Major facilitator Superfamily
ABC_RS09015	COG0768	penicillin binding
ABC_RS09035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABC_RS09040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABC_RS09050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABC_RS09055	COG1757	Na H antiporter
ABC_RS09065	COG0705	Rhomboid family
ABC_RS09065	COG0457	Tetratricopeptide repeat
ABC_RS09070	COG0697	spore germination
ABC_RS09090	COG1940	carbohydrate kinase activity
ABC_RS09095	COG1027	Aspartate ammonia-lyase
ABC_RS09100	COG0352	thiamine-phosphate diphosphorylase activity
ABC_RS09110	COG2022	thiamine diphosphate biosynthetic process
ABC_RS09115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC_RS09120	COG0352	thiamine-phosphate diphosphorylase activity
ABC_RS09120	COG0351	phosphomethylpyrimidine kinase
ABC_RS09130	COG0011	TIGRFAM Protein of
ABC_RS09135	COG2153	protein acetylation
ABC_RS09140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ABC_RS09145	COG2382	esterase
ABC_RS09155	COG1396	sequence-specific DNA binding
ABC_RS09160	COG1396	sequence-specific DNA binding
ABC_RS09165	COG0114	fumarate hydratase activity
ABC_RS09170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC_RS09175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC_RS09185	COG3852	Histidine kinase
ABC_RS09190	COG4129	membrane
ABC_RS09195	COG1376	ErfK ybiS ycfS ynhG family protein
ABC_RS09200	COG0346	lactoylglutathione lyase activity
ABC_RS09205	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABC_RS09210	COG1728	Protein conserved in bacteria
ABC_RS09220	COG0517	IMP dehydrogenase activity
ABC_RS09235	COG2861	carbohydrate metabolic process
ABC_RS09240	COG0789	Transcriptional regulator
ABC_RS09250	COG0527	aspartate kinase activity
ABC_RS09260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABC_RS09265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABC_RS09270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABC_RS09275	COG0367	asparagine synthase
ABC_RS09295	COG1510	regulation of RNA biosynthetic process
ABC_RS09300	COG2190	(PTS) system
ABC_RS09305	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ABC_RS09310	COG1850	ribulose-bisphosphate carboxylase activity
ABC_RS09315	COG1968	undecaprenyl-diphosphatase activity
ABC_RS09320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC_RS09325	COG0494	nUDIX hydrolase
ABC_RS09330	COG1300	Membrane
ABC_RS09335	COG0735	belongs to the Fur family
ABC_RS09345	COG4974	Belongs to the 'phage' integrase family
ABC_RS09350	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ABC_RS09360	COG1764	response to oxidative stress
ABC_RS09370	COG2814	Major facilitator Superfamily
ABC_RS09385	COG1988	membrane-bound metal-dependent
ABC_RS09395	COG1686	Belongs to the peptidase S11 family
ABC_RS09405	COG2172	sigma factor antagonist activity
ABC_RS09420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC_RS09435	COG0697	spore germination
ABC_RS09440	COG0019	diaminopimelate decarboxylase activity
ABC_RS09445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABC_RS09450	COG0583	DNA-binding transcription factor activity
ABC_RS09465	COG0372	Belongs to the citrate synthase family
ABC_RS09470	COG2079	MmgE PrpD family protein
ABC_RS09475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABC_RS09480	COG2084	Dehydrogenase
ABC_RS09485	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS09490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ABC_RS09500	COG0307	riboflavin synthase, alpha
ABC_RS09505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC_RS09505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABC_RS09510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABC_RS09515	COG1547	Domain of unknown function (DUF309)
ABC_RS09520	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABC_RS09525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABC_RS09535	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS09540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABC_RS09545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC_RS09550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABC_RS09560	COG2323	membrane
ABC_RS09575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC_RS09585	COG1686	Belongs to the peptidase S11 family
ABC_RS09590	COG2715	membrane protein required for spore maturation
ABC_RS09595	COG0700	Nucleoside recognition
ABC_RS09600	COG1187	pseudouridine synthase activity
ABC_RS09605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC_RS09610	COG1333	cytochrome c biogenesis protein
ABC_RS09615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC_RS09620	COG0745	RESPONSE REGULATOR receiver
ABC_RS09625	COG5002	protein histidine kinase activity
ABC_RS09630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC_RS09635	COG1120	ATPase activity
ABC_RS09645	COG0861	Integral membrane protein TerC family
ABC_RS09650	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC_RS09655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABC_RS09665	COG4955	Helix-turn-helix domain
ABC_RS09670	COG0514	ATP-dependent DNA helicase (RecQ)
ABC_RS09675	COG1266	CAAX protease self-immunity
ABC_RS09705	COG0438	transferase activity, transferring glycosyl groups
ABC_RS09710	COG0438	transferase activity, transferring glycosyl groups
ABC_RS09720	COG1473	amidohydrolase
ABC_RS09725	COG1408	metallophosphoesterase
ABC_RS09730	COG0789	Transcriptional regulator
ABC_RS09735	COG4862	establishment of competence for transformation
ABC_RS09740	COG0745	RESPONSE REGULATOR receiver
ABC_RS09745	COG5002	protein histidine kinase activity
ABC_RS09755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC_RS09760	COG0492	ferredoxin-NADP+ reductase activity
ABC_RS09770	COG2339	peptidase activity
ABC_RS09775	COG0626	cystathionine gamma-synthase activity
ABC_RS09780	COG0646	methionine synthase
ABC_RS09780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABC_RS09785	COG0646	methionine synthase
ABC_RS09785	COG1410	methionine synthase
ABC_RS09790	COG3409	Peptidoglycan-binding domain 1 protein
ABC_RS09790	COG3773	Cell wall hydrolase
ABC_RS09795	COG2959	enzyme of heme biosynthesis
ABC_RS09800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABC_RS09805	COG0204	Acyl-transferase
ABC_RS09810	COG0539	negative regulation of cytoplasmic translation
ABC_RS09820	COG1160	GTP binding
ABC_RS09825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABC_RS09830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ABC_RS09850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABC_RS09855	COG0302	gtp cyclohydrolase
ABC_RS09865	COG0142	geranyltranstransferase activity
ABC_RS09870	COG2226	methyltransferase
ABC_RS09875	COG0109	protoheme IX farnesyltransferase activity
ABC_RS09885	COG0142	geranyltranstransferase activity
ABC_RS09890	COG0105	UTP biosynthetic process
ABC_RS09895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABC_RS09900	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABC_RS09905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABC_RS09910	COG4401	Chorismate mutase type I
ABC_RS09920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABC_RS09925	COG0134	indole-3-glycerol-phosphate synthase activity
ABC_RS09930	COG0135	phosphoribosylanthranilate isomerase activity
ABC_RS09935	COG0133	tryptophan synthase activity
ABC_RS09940	COG0159	tryptophan synthase activity
ABC_RS09945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABC_RS09950	COG0287	Prephenate dehydrogenase
ABC_RS09955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABC_RS09960	COG0457	Tetratricopeptide repeat
ABC_RS09965	COG5582	Belongs to the UPF0302 family
ABC_RS09975	COG0723	plastoquinol--plastocyanin reductase activity
ABC_RS09980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABC_RS09990	COG4347	Protein of unknown function (DUF1405)
ABC_RS10000	COG2738	Putative neutral zinc metallopeptidase
ABC_RS10005	COG2814	Major facilitator Superfamily
ABC_RS10010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC_RS10015	COG1694	Mazg nucleotide pyrophosphohydrolase
ABC_RS10020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ABC_RS10025	COG1803	Methylglyoxal synthase
ABC_RS10035	COG1690	Belongs to the RtcB family
ABC_RS10045	COG2153	protein acetylation
ABC_RS10065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABC_RS10075	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ABC_RS10080	COG2226	methyltransferase
ABC_RS10085	COG3584	3D domain protein
ABC_RS10085	COG1388	LysM domain
ABC_RS10095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABC_RS10100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABC_RS10105	COG1011	Hydrolase
ABC_RS10115	COG1122	ATPase activity
ABC_RS10120	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABC_RS10125	COG2094	Belongs to the DNA glycosylase MPG family
ABC_RS10135	COG1388	LysM domain
ABC_RS10135	COG0791	NLP P60 protein
ABC_RS10145	COG1309	transcriptional regulator
ABC_RS10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC_RS10160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC_RS10165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC_RS10170	COG0626	cystathionine gamma-synthase activity
ABC_RS10175	COG2329	Antibiotic biosynthesis monooxygenase
ABC_RS10195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC_RS10205	COG1082	Xylose isomerase domain protein TIM barrel
ABC_RS10210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ABC_RS10215	COG3048	D-serine ammonia-lyase activity
ABC_RS10220	COG0708	Exodeoxyribonuclease III
ABC_RS10225	COG0217	transcriptional regulatory protein
ABC_RS10240	COG0697	spore germination
ABC_RS10245	COG2151	metal-sulfur cluster biosynthetic enzyme
ABC_RS10250	COG0733	neurotransmitter:sodium symporter activity
ABC_RS10255	COG2207	Transcriptional regulator
ABC_RS10255	COG3708	Transcriptional regulator
ABC_RS10260	COG1695	Transcriptional regulator
ABC_RS10270	COG2814	Major facilitator Superfamily
ABC_RS10295	COG1131	(ABC) transporter
ABC_RS10305	COG1595	DNA-templated transcription, initiation
ABC_RS10315	COG0596	Alpha beta hydrolase
ABC_RS10330	COG1413	lyase activity
ABC_RS10340	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ABC_RS10350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC_RS10355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABC_RS10360	COG1360	Flagellar Motor Protein
ABC_RS10365	COG0628	permease
ABC_RS10370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABC_RS10380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABC_RS10385	COG0187	DNA topoisomerase II activity
ABC_RS10390	COG1832	CoA-binding protein
ABC_RS10400	COG0517	IMP dehydrogenase activity
ABC_RS10400	COG1125	glycine betaine transport
ABC_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS10415	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ABC_RS10440	COG1070	Carbohydrate kinase
ABC_RS10480	COG3290	protein histidine kinase activity
ABC_RS10480	COG0840	transmembrane signaling receptor activity
ABC_RS10490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC_RS10495	COG0028	Belongs to the TPP enzyme family
ABC_RS10500	COG0673	inositol 2-dehydrogenase activity
ABC_RS10505	COG0116	Belongs to the methyltransferase superfamily
ABC_RS10525	COG0328	RNA-DNA hybrid ribonuclease activity
ABC_RS10530	COG3599	regulation of cell shape
ABC_RS10535	COG4474	Belongs to the UPF0398 family
ABC_RS10545	COG3359	exonuclease
ABC_RS10550	COG1205	dead DEAH box helicase
ABC_RS10550	COG1111	helicase
ABC_RS10560	COG0697	spore germination
ABC_RS10565	COG0814	amino acid
ABC_RS10580	COG0400	carboxylic ester hydrolase activity
ABC_RS10585	COG0346	lactoylglutathione lyase activity
ABC_RS10590	COG0561	phosphatase activity
ABC_RS10620	COG0493	'glutamate synthase
ABC_RS10625	COG0067	glutamate synthase
ABC_RS10625	COG0069	glutamate synthase activity
ABC_RS10625	COG0070	glutamate synthase
ABC_RS10650	COG3428	Bacterial PH domain
ABC_RS10655	COG3402	PFAM membrane-flanked domain
ABC_RS10665	COG1413	lyase activity
ABC_RS10690	COG1234	tRNA 3'-trailer cleavage
ABC_RS10695	COG0693	protein deglycase activity
ABC_RS10700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABC_RS10715	COG0789	Transcriptional regulator
ABC_RS10725	COG3331	DNA recombination
ABC_RS10730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC_RS10730	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABC_RS10735	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABC_RS10740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABC_RS10745	COG3935	DnaD domain protein
ABC_RS10750	COG0017	Asparaginyl-tRNA synthetase
ABC_RS10770	COG0402	S-adenosylhomocysteine deaminase activity
ABC_RS10775	COG1199	ATP-dependent helicase activity
ABC_RS10775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABC_RS10785	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABC_RS10790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABC_RS10795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABC_RS10805	COG0617	tRNA 3'-terminal CCA addition
ABC_RS10810	COG0438	transferase activity, transferring glycosyl groups
ABC_RS10835	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC_RS10835	COG2247	cell wall binding repeat
ABC_RS10845	COG2188	Transcriptional regulator
ABC_RS10850	COG1486	melibiose metabolic process
ABC_RS10855	COG3394	polysaccharide catabolic process
ABC_RS10860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS10860	COG1263	PTS System
ABC_RS10890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABC_RS10895	COG1263	PTS System
ABC_RS10895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS10900	COG0561	phosphatase activity
ABC_RS10915	COG0438	transferase activity, transferring glycosyl groups
ABC_RS10960	COG3069	C4-dicarboxylate transmembrane transporter activity
ABC_RS10965	COG1960	acyl-CoA dehydrogenase activity
ABC_RS10970	COG4876	unkown
ABC_RS10975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC_RS10980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABC_RS10985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABC_RS10990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABC_RS11010	COG0514	ATP-dependent DNA helicase (RecQ)
ABC_RS11015	COG0656	L-ascorbic acid biosynthetic process
ABC_RS11020	COG0488	(ABC) transporter
ABC_RS11030	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC_RS11035	COG0567	Dehydrogenase, E1 component
ABC_RS11045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC_RS11055	COG1764	response to oxidative stress
ABC_RS11060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABC_RS11060	COG0551	DNA topoisomerase type I activity
ABC_RS11065	COG1131	(ABC) transporter
ABC_RS11080	COG4585	Histidine kinase
ABC_RS11090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABC_RS11095	COG0602	queuosine metabolic process
ABC_RS11100	COG0720	synthase
ABC_RS11105	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABC_RS11110	COG2309	aminopeptidase activity
ABC_RS11115	COG1115	amino acid carrier protein
ABC_RS11120	COG1254	Belongs to the acylphosphatase family
ABC_RS11130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC_RS11140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC_RS11160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABC_RS11175	COG0835	chemotaxis
ABC_RS11175	COG0784	Response regulator, receiver
ABC_RS11200	COG2200	EAL domain
ABC_RS11220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABC_RS11225	COG0824	Thioesterase
ABC_RS11230	COG0464	growth
ABC_RS11250	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABC_RS11270	COG1132	(ABC) transporter
ABC_RS11275	COG1132	(ABC) transporter
ABC_RS11280	COG3763	UPF0154 protein
ABC_RS11290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABC_RS11295	COG4224	UPF0291 protein
ABC_RS11300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ABC_RS11305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC_RS11310	COG2814	Major facilitator Superfamily
ABC_RS11315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABC_RS11330	COG1414	Transcriptional regulator
ABC_RS11335	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABC_RS11340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABC_RS11345	COG0277	FAD linked oxidase domain protein
ABC_RS11350	COG0247	lactate metabolic process
ABC_RS11355	COG0277	FAD linked oxidase domain protein
ABC_RS11365	COG0174	glutamine synthetase
ABC_RS11370	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ABC_RS11375	COG0464	growth
ABC_RS11385	COG1923	regulation of RNA biosynthetic process
ABC_RS11390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABC_RS11400	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABC_RS11405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABC_RS11415	COG4550	Control of competence regulator ComK, YlbF/YmcA
ABC_RS11420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABC_RS11430	COG2359	stage V sporulation protein S
ABC_RS11435	COG1692	metallophosphoesterase
ABC_RS11440	COG1418	mRNA catabolic process
ABC_RS11465	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABC_RS11470	COG0513	Belongs to the DEAD box helicase family
ABC_RS11475	COG1058	Belongs to the CinA family
ABC_RS11475	COG1546	Belongs to the CinA family
ABC_RS11480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABC_RS11485	COG1426	Protein conserved in bacteria
ABC_RS11500	COG0300	oxidoreductase activity
ABC_RS11505	COG0612	Peptidase, M16
ABC_RS11510	COG0612	Peptidase, M16
ABC_RS11515	COG2188	Transcriptional regulator
ABC_RS11520	COG1674	ftsk spoiiie
ABC_RS11530	COG0740	serine-type endopeptidase activity
ABC_RS11535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABC_RS11540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC_RS11545	COG0527	aspartate kinase activity
ABC_RS11550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABC_RS11555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC_RS11560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABC_RS11570	COG0612	Peptidase, M16
ABC_RS11575	COG0726	polysaccharide deacetylase
ABC_RS11580	COG1185	polyribonucleotide nucleotidyltransferase activity
ABC_RS11585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABC_RS11590	COG0196	riboflavin kinase activity
ABC_RS11595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABC_RS11600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABC_RS11610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABC_RS11615	COG1358	cellular component organization or biogenesis
ABC_RS11620	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ABC_RS11625	COG0195	Participates in both transcription termination and antitermination
ABC_RS11630	COG0779	Required for maturation of 30S ribosomal subunits
ABC_RS11635	COG2176	DNA-directed DNA polymerase activity
ABC_RS11640	COG0442	prolyl-tRNA aminoacylation
ABC_RS11645	COG0750	zinc metalloprotease
ABC_RS11650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABC_RS11655	COG4589	Belongs to the CDS family
ABC_RS11660	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABC_RS11665	COG0233	cytoplasmic translational termination
ABC_RS11670	COG0528	UMP kinase activity
ABC_RS11675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ABC_RS11680	COG0052	Belongs to the universal ribosomal protein uS2 family
ABC_RS11690	COG1191	sigma factor activity
ABC_RS11695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABC_RS11715	COG1419	protein localization to endoplasmic reticulum
ABC_RS11720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC_RS11725	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABC_RS11730	COG1684	flagellar biosynthetic protein fliR
ABC_RS11735	COG1987	bacterial-type flagellum assembly
ABC_RS11740	COG1338	Plays a role in the flagellum-specific transport system
ABC_RS11745	COG3190	flagellar
ABC_RS11750	COG2201	protein-glutamate methylesterase activity
ABC_RS11755	COG1776	CheC inhibitor of MCP methylation
ABC_RS11755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC_RS11760	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC_RS11775	COG4786	Flagellar basal body rod
ABC_RS11780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ABC_RS11800	COG1157	protein secretion by the type III secretion system
ABC_RS11805	COG1317	bacterial-type flagellum organization
ABC_RS11810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABC_RS11815	COG1766	The M ring may be actively involved in energy transduction
ABC_RS11820	COG1677	Flagellar hook-basal body complex protein FliE
ABC_RS11825	COG1558	bacterial-type flagellum-dependent cell motility
ABC_RS11830	COG1815	bacterial-type flagellum-dependent cell motility
ABC_RS11835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ABC_RS11840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABC_RS11845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ABC_RS11850	COG4974	Belongs to the 'phage' integrase family
ABC_RS11855	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ABC_RS11860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABC_RS11865	COG0758	DNA mediated transformation
ABC_RS11870	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABC_RS11875	COG0045	succinate-CoA ligase (ADP-forming) activity
ABC_RS11890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABC_RS11910	COG0335	large ribosomal subunit rRNA binding
ABC_RS11915	COG0018	arginyl-trna synthetase
ABC_RS11920	COG0336	Belongs to the RNA methyltransferase TrmD family
ABC_RS11925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABC_RS11935	COG1837	Belongs to the UPF0109 family
ABC_RS11940	COG0228	four-way junction DNA binding
ABC_RS11945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABC_RS11950	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ABC_RS11955	COG0552	protein localization to endoplasmic reticulum
ABC_RS11960	COG1196	nuclear chromosome segregation
ABC_RS11970	COG0571	ribonuclease III activity
ABC_RS11975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABC_RS11980	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS11985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABC_RS11990	COG0416	fatty acid biosynthetic process
ABC_RS11995	COG1349	DNA-binding transcription factor activity
ABC_RS12000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABC_RS12005	COG1760	l-serine dehydratase
ABC_RS12010	COG1760	l-serine dehydratase
ABC_RS12015	COG1307	EDD domain protein, DegV family
ABC_RS12020	COG1461	Dihydroxyacetone kinase
ABC_RS12025	COG1302	Protein conserved in bacteria
ABC_RS12030	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABC_RS12040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABC_RS12045	COG1162	GTPase activity
ABC_RS12050	COG2815	serine threonine protein kinase
ABC_RS12050	COG0515	serine threonine protein kinase
ABC_RS12055	COG0631	protein serine/threonine phosphatase activity
ABC_RS12060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC_RS12060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABC_RS12065	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ABC_RS12070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABC_RS12075	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABC_RS12080	COG1758	RNA polymerase activity
ABC_RS12085	COG0194	GDP metabolic process
ABC_RS12090	COG2052	Domain of unknown function (DUF370)
ABC_RS12095	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABC_RS12105	COG4485	Bacterial membrane protein, YfhO
ABC_RS12120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABC_RS12125	COG0284	orotidine-5'-phosphate decarboxylase activity
ABC_RS12130	COG0167	dihydroorotate dehydrogenase activity
ABC_RS12135	COG0543	2 iron, 2 sulfur cluster binding
ABC_RS12140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC_RS12145	COG0505	Belongs to the CarA family
ABC_RS12150	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABC_RS12155	COG0540	Belongs to the ATCase OTCase family
ABC_RS12160	COG2233	PERMEase
ABC_RS12165	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ABC_RS12170	COG0564	pseudouridine synthase activity
ABC_RS12175	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABC_RS12180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABC_RS12185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABC_RS12190	COG3599	regulation of cell shape
ABC_RS12195	COG2302	S4 RNA-binding domain
ABC_RS12200	COG0762	integral membrane protein
ABC_RS12205	COG1799	cell septum assembly
ABC_RS12210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABC_RS12220	COG1873	PFAM PRC-barrel domain
ABC_RS12225	COG1191	sigma factor activity
ABC_RS12230	COG1191	sigma factor activity
ABC_RS12240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABC_RS12245	COG0849	cell division
ABC_RS12250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABC_RS12255	COG0772	Belongs to the SEDS family
ABC_RS12260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABC_RS12265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC_RS12270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABC_RS12275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABC_RS12280	COG0768	penicillin binding
ABC_RS12285	COG0768	penicillin binding
ABC_RS12290	COG4839	cell division protein FtsL
ABC_RS12295	COG0275	rRNA processing
ABC_RS12300	COG2001	Belongs to the MraZ family
ABC_RS12305	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ABC_RS12315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABC_RS12320	COG0454	-acetyltransferase
ABC_RS12330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABC_RS12335	COG1399	metal-binding, possibly nucleic acid-binding protein
ABC_RS12340	COG1323	Belongs to the UPF0348 family
ABC_RS12345	COG3480	Lon protease (S16) C-terminal proteolytic domain
ABC_RS12350	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABC_RS12355	COG3314	Sporulation integral membrane protein YlbJ
ABC_RS12360	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABC_RS12365	COG0742	ribosomal rna small subunit methyltransferase
ABC_RS12375	COG4471	UPF0298 protein
ABC_RS12405	COG2340	Cysteine-rich secretory protein family
ABC_RS12420	COG2322	membrane
ABC_RS12425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABC_RS12430	COG1845	cytochrome c oxidase, subunit III
ABC_RS12435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABC_RS12440	COG2010	Cytochrome c
ABC_RS12440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABC_RS12445	COG1612	heme a metabolic process
ABC_RS12450	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ABC_RS12455	COG4838	Belongs to the UPF0358 family
ABC_RS12460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABC_RS12465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABC_RS12470	COG4896	Protein conserved in bacteria
ABC_RS12480	COG1217	gtp-binding protein TYPA
ABC_RS12495	COG0483	inositol monophosphate 1-phosphatase activity
ABC_RS12500	COG4493	Belongs to the UPF0637 family
ABC_RS12510	COG1982	Orn Lys Arg decarboxylase major
ABC_RS12525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABC_RS12535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS12540	COG0601	transmembrane transport
ABC_RS12550	COG4608	Belongs to the ABC transporter superfamily
ABC_RS12555	COG0444	Belongs to the ABC transporter superfamily
ABC_RS12565	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC_RS12570	COG0022	dehydrogenase e1 component
ABC_RS12590	COG0242	peptide deformylase activity
ABC_RS12595	COG5503	Protein of unknown function (DUF1447)
ABC_RS12600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABC_RS12605	COG0569	domain protein
ABC_RS12610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC_RS12615	COG0450	alkyl hydroperoxide reductase
ABC_RS12620	COG0668	transmembrane transport
ABC_RS12630	COG1473	amidohydrolase
ABC_RS12635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC_RS12640	COG2171	N-acyltransferase activity
ABC_RS12655	COG0668	transmembrane transport
ABC_RS12675	COG0702	epimerase
ABC_RS12685	COG1902	pentaerythritol trinitrate reductase activity
ABC_RS12700	COG2608	mercury ion transmembrane transporter activity
ABC_RS12705	COG1937	Protein conserved in bacteria
ABC_RS12715	COG0561	phosphatase activity
ABC_RS12735	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC_RS12740	COG0022	dehydrogenase e1 component
ABC_RS12745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC_RS12750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABC_RS12760	COG3829	transcription factor binding
ABC_RS12760	COG3290	protein histidine kinase activity
ABC_RS12780	COG0745	RESPONSE REGULATOR receiver
ABC_RS12785	COG0750	zinc metalloprotease
ABC_RS12790	COG0497	DNA recombination
ABC_RS12795	COG1438	arginine binding
ABC_RS12800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ABC_RS12805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABC_RS12810	COG0142	geranyltranstransferase activity
ABC_RS12815	COG1722	exodeoxyribonuclease VII activity
ABC_RS12820	COG1570	exodeoxyribonuclease VII activity
ABC_RS12825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABC_RS12830	COG1302	Protein conserved in bacteria
ABC_RS12835	COG0439	Biotin carboxylase
ABC_RS12840	COG0511	ligase activity, forming carbon-carbon bonds
ABC_RS12885	COG3854	ATPases associated with a variety of cellular activities
ABC_RS12900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABC_RS12905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABC_RS12910	COG0006	proline dipeptidase activity
ABC_RS12925	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABC_RS12930	COG1321	iron dependent repressor
ABC_RS12935	COG1533	DNA photolyase activity
ABC_RS12945	COG3973	AAA domain
ABC_RS12950	COG0095	Lipoate-protein ligase
ABC_RS12955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABC_RS12960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC_RS12965	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABC_RS12970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABC_RS12975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABC_RS12990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABC_RS13025	COG4537	Required for transformation and DNA binding
ABC_RS13030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABC_RS13085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABC_RS13090	COG0210	DNA helicase
ABC_RS13120	COG2226	methyltransferase
ABC_RS13135	COG0564	pseudouridine synthase activity
ABC_RS13140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABC_RS13145	COG2357	RelA SpoT domain protein
ABC_RS13155	COG4116	CYTH
ABC_RS13160	COG0741	lytic transglycosylase activity
ABC_RS13165	COG2346	COG2346, Truncated hemoglobins
ABC_RS13170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ABC_RS13185	COG4862	establishment of competence for transformation
ABC_RS13190	COG1393	Belongs to the ArsC family
ABC_RS13195	COG0456	acetyltransferase
ABC_RS13210	COG1272	protein, Hemolysin III
ABC_RS13215	COG1418	mRNA catabolic process
ABC_RS13220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC_RS13225	COG0180	Tryptophanyl-tRNA synthetase
ABC_RS13240	COG2357	RelA SpoT domain protein
ABC_RS13245	COG1072	(Pantothenic acid kinase))
ABC_RS13250	COG2340	Cysteine-rich secretory protein family
ABC_RS13255	COG3409	Peptidoglycan-binding domain 1 protein
ABC_RS13255	COG3773	Cell wall hydrolase
ABC_RS13265	COG0617	tRNA 3'-terminal CCA addition
ABC_RS13280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABC_RS13285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABC_RS13300	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABC_RS13315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABC_RS13320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC_RS13325	COG0505	Belongs to the CarA family
ABC_RS13330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABC_RS13335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABC_RS13340	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABC_RS13345	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABC_RS13350	COG3336	cytochrome c oxidase
ABC_RS13355	COG0561	phosphatase activity
ABC_RS13375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABC_RS13385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC_RS13390	COG1073	alpha beta
ABC_RS13400	COG0425	Belongs to the sulfur carrier protein TusA family
ABC_RS13400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABC_RS13410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABC_RS13415	COG1834	amidinotransferase
ABC_RS13430	COG3209	COG3209 Rhs family protein
ABC_RS13450	COG0367	asparagine synthase
ABC_RS13455	COG0835	chemotaxis
ABC_RS13460	COG2198	Histidine kinase
ABC_RS13460	COG0643	Histidine kinase
ABC_RS13485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC_RS13490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABC_RS13495	COG0581	inorganic phosphate transmembrane transporter activity
ABC_RS13500	COG0573	inorganic phosphate transmembrane transporter activity
ABC_RS13505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABC_RS13510	COG2318	DinB family
ABC_RS13520	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABC_RS13525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC_RS13530	COG1573	uracil-dna glycosylase
ABC_RS13535	COG1228	amidohydrolase
ABC_RS13540	COG2002	toxin-antitoxin pair type II binding
ABC_RS13545	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ABC_RS13550	COG2868	ribosomal protein
ABC_RS13555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABC_RS13560	COG1530	ribonuclease E activity
ABC_RS13565	COG1994	Peptidase M50
ABC_RS13570	COG0739	heme binding
ABC_RS13575	COG0667	Aldo Keto reductase
ABC_RS13580	COG1268	BioY protein
ABC_RS13585	COG0315	cyclic pyranopterin monophosphate synthase activity
ABC_RS13590	COG0693	protein deglycase activity
ABC_RS13595	COG2894	cell division
ABC_RS13600	COG0850	regulation of cytokinetic process
ABC_RS13605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ABC_RS13615	COG1077	Cell shape determining protein MreB Mrl
ABC_RS13620	COG2003	Belongs to the UPF0758 family
ABC_RS13625	COG0424	maF-like protein
ABC_RS13630	COG0823	Involved in the tonB-independent uptake of proteins
ABC_RS13630	COG4946	Tricorn protease homolog
ABC_RS13630	COG1506	peptidase
ABC_RS13640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABC_RS13645	COG0285	dihydrofolate synthase activity
ABC_RS13650	COG0525	valine-tRNA ligase activity
ABC_RS13675	COG1388	LysM domain
ABC_RS13675	COG1388	LysM domain
ABC_RS13680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABC_RS13685	COG0113	porphobilinogen synthase activity
ABC_RS13695	COG0181	hydroxymethylbilane synthase activity
ABC_RS13700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABC_RS13705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABC_RS13710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABC_RS13715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABC_RS13720	COG1067	ATP-dependent peptidase activity
ABC_RS13720	COG0470	DNA polymerase III
ABC_RS13725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ABC_RS13730	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABC_RS13735	COG0457	Tetratricopeptide repeat
ABC_RS13735	COG1477	protein flavinylation
ABC_RS13740	COG0066	3-isopropylmalate dehydratase activity
ABC_RS13745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABC_RS13750	COG0473	3-isopropylmalate dehydrogenase activity
ABC_RS13755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABC_RS13760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABC_RS13765	COG0440	acetolactate synthase activity
ABC_RS13770	COG0028	Belongs to the TPP enzyme family
ABC_RS13775	COG0129	dihydroxy-acid dehydratase activity
ABC_RS13790	COG2132	Multicopper oxidase
ABC_RS13805	COG0622	Phosphoesterase
ABC_RS13810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABC_RS13815	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABC_RS13820	COG5401	PFAM Sporulation and spore germination
ABC_RS13825	COG1054	Belongs to the UPF0176 family
ABC_RS13835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABC_RS13840	COG1846	Transcriptional regulator
ABC_RS13845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABC_RS13850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS13855	COG2197	response regulator
ABC_RS13860	COG0824	Thioesterase
ABC_RS13865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABC_RS13870	COG1053	succinate dehydrogenase
ABC_RS13875	COG2009	succinate dehydrogenase
ABC_RS13880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABC_RS13890	COG0322	excinuclease ABC activity
ABC_RS13895	COG3118	belongs to the thioredoxin family
ABC_RS13900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ABC_RS13905	COG2086	electron transfer activity
ABC_RS13910	COG1024	Enoyl-CoA hydratase
ABC_RS13915	COG1309	transcriptional regulator
ABC_RS13920	COG0318	PFAM AMP-dependent synthetase and ligase
ABC_RS13925	COG3766	membrane
ABC_RS13930	COG1193	negative regulation of DNA recombination
ABC_RS13935	COG1796	DNA polymerase
ABC_RS13935	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABC_RS13940	COG1286	toxin biosynthetic process
ABC_RS13945	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ABC_RS13950	COG0072	phenylalanine-tRNA ligase activity
ABC_RS13955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABC_RS13960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABC_RS13980	COG1363	Peptidase, m42
ABC_RS13990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC_RS13995	COG3162	membrane
ABC_RS14000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABC_RS14005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ABC_RS14010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABC_RS14015	COG0577	efflux transmembrane transporter activity
ABC_RS14020	COG1136	(ABC) transporter
ABC_RS14035	COG2027	D-alanyl-D-alanine carboxypeptidase
ABC_RS14050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC_RS14060	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABC_RS14065	COG1484	DNA-dependent DNA replication
ABC_RS14070	COG3611	Membrane attachment protein
ABC_RS14075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABC_RS14085	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABC_RS14090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABC_RS14095	COG0237	dephospho-CoA kinase activity
ABC_RS14100	COG1971	Probably functions as a manganese efflux pump
ABC_RS14105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABC_RS14110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABC_RS14110	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABC_RS14115	COG5002	protein histidine kinase activity
ABC_RS14120	COG0745	RESPONSE REGULATOR receiver
ABC_RS14125	COG1522	sequence-specific DNA binding
ABC_RS14130	COG0039	L-malate dehydrogenase activity
ABC_RS14135	COG0538	isocitrate dehydrogenase activity
ABC_RS14140	COG0372	Belongs to the citrate synthase family
ABC_RS14145	COG2707	UPF0756 membrane protein
ABC_RS14150	COG3030	protein affecting phage T7 exclusion by the F plasmid
ABC_RS14160	COG0205	6-phosphofructokinase activity
ABC_RS14165	COG0825	malonyl-CoA metabolic process
ABC_RS14170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABC_RS14175	COG2186	Transcriptional regulator
ABC_RS14180	COG0281	malic enzyme
ABC_RS14185	COG0587	DNA-directed DNA polymerase activity
ABC_RS14200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABC_RS14210	COG4109	DRTGG domain
ABC_RS14220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABC_RS14225	COG0006	proline dipeptidase activity
ABC_RS14235	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS14240	COG0165	Argininosuccinate lyase
ABC_RS14245	COG0137	argininosuccinate synthase activity
ABC_RS14255	COG3481	metal-dependent phosphohydrolase, HD sub domain
ABC_RS14260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABC_RS14265	COG0827	DNA restriction-modification system
ABC_RS14270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABC_RS14275	COG2814	Major facilitator Superfamily
ABC_RS14280	COG3874	Sporulation protein YtfJ
ABC_RS14290	COG1714	RDD family
ABC_RS14295	COG0616	signal peptide processing
ABC_RS14305	COG0301	tRNA thio-modification
ABC_RS14310	COG1104	cysteine desulfurase activity
ABC_RS14315	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ABC_RS14320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABC_RS14325	COG1309	transcriptional regulator
ABC_RS14335	COG1956	GAF domain-containing protein
ABC_RS14340	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABC_RS14345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABC_RS14350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC_RS14350	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABC_RS14355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC_RS14360	COG0454	-acetyltransferase
ABC_RS14365	COG0517	IMP dehydrogenase activity
ABC_RS14370	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABC_RS14380	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ABC_RS14380	COG1605	Chorismate mutase
ABC_RS14385	COG4980	gas vesicle protein
ABC_RS14390	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ABC_RS14395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABC_RS14400	COG1674	ftsk spoiiie
ABC_RS14405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABC_RS14410	COG4848	Belongs to the UPF0354 family
ABC_RS14415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC_RS14430	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ABC_RS14435	COG1363	Peptidase, m42
ABC_RS14445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABC_RS14455	COG0510	thiamine kinase activity
ABC_RS14460	COG0788	formyltetrahydrofolate deformylase activity
ABC_RS14475	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABC_RS14480	COG0022	dehydrogenase e1 component
ABC_RS14485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABC_RS14500	COG1346	cytolysis
ABC_RS14505	COG1380	Effector of murein hydrolase LrgA
ABC_RS14515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABC_RS14520	COG3708	Transcriptional regulator
ABC_RS14520	COG2207	Transcriptional regulator
ABC_RS14525	COG0789	Transcriptional regulator
ABC_RS14530	COG0300	oxidoreductase activity
ABC_RS14535	COG0346	lactoylglutathione lyase activity
ABC_RS14540	COG1349	DNA-binding transcription factor activity
ABC_RS14545	COG1187	pseudouridine synthase activity
ABC_RS14550	COG0772	Belongs to the SEDS family
ABC_RS14555	COG0772	Belongs to the SEDS family
ABC_RS14560	COG2244	polysaccharide biosynthetic process
ABC_RS14565	COG3386	PFAM SMP-30 Gluconolaconase
ABC_RS14570	COG0432	Pfam Uncharacterised protein family UPF0047
ABC_RS14575	COG1473	amidohydrolase
ABC_RS14580	COG2081	HI0933 family
ABC_RS14595	COG1793	dna ligase
ABC_RS14665	COG5434	Belongs to the glycosyl hydrolase 28 family
ABC_RS14805	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ABC_RS14810	COG0756	dUTP diphosphatase activity
ABC_RS14870	COG3561	AntA/AntB antirepressor
ABC_RS14945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABC_RS14955	COG2081	HI0933 family
ABC_RS14980	COG0495	leucyl-tRNA aminoacylation
ABC_RS14985	COG0039	L-malate dehydrogenase activity
ABC_RS14995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ABC_RS15000	COG0288	reversible hydration of carbon dioxide
ABC_RS15005	COG2267	carboxylic ester hydrolase activity
ABC_RS15010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABC_RS15015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABC_RS15020	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ABC_RS15025	COG1506	peptidase
ABC_RS15030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC_RS15035	COG1116	anion transmembrane transporter activity
ABC_RS15040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC_RS15045	COG0494	nUDIX hydrolase
ABC_RS15050	COG2814	Major facilitator Superfamily
ABC_RS15060	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABC_RS15065	COG1428	Deoxynucleoside kinase
ABC_RS15070	COG1428	Deoxynucleoside kinase
ABC_RS15085	COG4604	ABC transporter, ATP-binding protein
ABC_RS15090	COG4605	iron ion homeostasis
ABC_RS15095	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC_RS15100	COG0671	phosphoesterase, PA-phosphatase related
ABC_RS15105	COG1823	symporter activity
ABC_RS15125	COG4846	Membrane protein involved in cytochrome C biogenesis
ABC_RS15130	COG0109	protoheme IX farnesyltransferase activity
ABC_RS15135	COG1227	inorganic diphosphatase activity
ABC_RS15150	COG0166	Belongs to the GPI family
ABC_RS15155	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABC_RS15160	COG1979	alcohol dehydrogenase
ABC_RS15165	COG2155	Conserved Protein
ABC_RS15170	COG1098	S1 RNA binding domain
ABC_RS15180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ABC_RS15185	COG0436	Aminotransferase
ABC_RS15190	COG1522	sequence-specific DNA binding
ABC_RS15195	COG1854	S-ribosylhomocysteine lyase activity
ABC_RS15200	COG1295	ribonuclease BN
ABC_RS15205	COG0776	regulation of translation
ABC_RS15210	COG2056	Na+-H+ antiporter family
ABC_RS15220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABC_RS15225	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ABC_RS15230	COG3584	3D domain protein
ABC_RS15240	COG1252	NADH dehydrogenase
ABC_RS15245	COG0492	ferredoxin-NADP+ reductase activity
ABC_RS15250	COG0246	Mannitol dehydrogenase
ABC_RS15255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS15260	COG3711	transcriptional antiterminator
ABC_RS15270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABC_RS15275	COG0765	amino acid transport
ABC_RS15280	COG0316	Belongs to the HesB IscA family
ABC_RS15290	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ABC_RS15295	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABC_RS15305	COG4844	belongs to the
ABC_RS15310	COG1252	NADH dehydrogenase
ABC_RS15315	COG4837	Protein of unknown function (DUF1462)
ABC_RS15320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABC_RS15325	COG0083	homoserine kinase activity
ABC_RS15330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABC_RS15335	COG0460	homoserine dehydrogenase
ABC_RS15340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABC_RS15345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC_RS15350	COG0647	UMP catabolic process
ABC_RS15355	COG2445	Protein of unknown function DUF86
ABC_RS15365	COG4470	Protein conserved in bacteria
ABC_RS15375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABC_RS15380	COG0739	heme binding
ABC_RS15385	COG1757	Na H antiporter
ABC_RS15400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABC_RS15405	COG3377	Domain of unknown function (DUF1805)
ABC_RS15410	COG0737	Belongs to the 5'-nucleotidase family
ABC_RS15415	COG0730	response to heat
ABC_RS15420	COG1801	Protein of unknown function DUF72
ABC_RS15460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ABC_RS15465	COG2207	Transcriptional regulator
ABC_RS15465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC_RS15470	COG0667	Aldo Keto reductase
ABC_RS15475	COG2226	methyltransferase
ABC_RS15480	COG2723	6-phospho-beta-galactosidase activity
ABC_RS15485	COG3711	transcriptional antiterminator
ABC_RS15490	COG2224	Isocitrate lyase
ABC_RS15495	COG0719	Fe-S assembly protein
ABC_RS15500	COG0822	iron-sulfur transferase activity
ABC_RS15505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC_RS15510	COG0719	Fe-S assembly protein
ABC_RS15515	COG0396	ATPase activity
ABC_RS15520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABC_RS15525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC_RS15535	COG1464	Belongs to the NlpA lipoprotein family
ABC_RS15540	COG2011	ABC-type metal ion transport system permease component
ABC_RS15545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABC_RS15550	COG0509	glycine decarboxylation via glycine cleavage system
ABC_RS15555	COG1393	Belongs to the ArsC family
ABC_RS15560	COG1960	acyl-CoA dehydrogenase activity
ABC_RS15565	COG0183	Belongs to the thiolase family
ABC_RS15570	COG1024	Enoyl-CoA hydratase
ABC_RS15570	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC_RS15580	COG4533	DNA binding
ABC_RS15595	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ABC_RS15600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABC_RS15605	COG3314	Sporulation integral membrane protein YlbJ
ABC_RS15625	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABC_RS15630	COG2259	Doxx family
ABC_RS15635	COG0557	exoribonuclease II activity
ABC_RS15640	COG1647	Serine aminopeptidase, S33
ABC_RS15650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC_RS15655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABC_RS15680	COG4948	Mandelate Racemase Muconate Lactonizing
ABC_RS15685	COG1012	belongs to the aldehyde dehydrogenase family
ABC_RS15690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC_RS15695	COG1802	Transcriptional regulator
ABC_RS15700	COG0148	phosphopyruvate hydratase activity
ABC_RS15705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABC_RS15710	COG0149	triose-phosphate isomerase activity
ABC_RS15715	COG0126	phosphoglycerate kinase activity
ABC_RS15745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABC_RS15750	COG0740	serine-type endopeptidase activity
ABC_RS15755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC_RS15765	COG1125	glycine betaine transport
ABC_RS15765	COG0517	IMP dehydrogenase activity
ABC_RS15770	COG1174	glycine betaine transport
ABC_RS15775	COG1732	Glycine betaine
ABC_RS15780	COG1174	glycine betaine transport
ABC_RS15785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS15790	COG1481	regulation of sporulation
ABC_RS15795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ABC_RS15800	COG1660	Displays ATPase and GTPase activities
ABC_RS15805	COG1051	belongs to the nudix hydrolase family
ABC_RS15810	COG0492	ferredoxin-NADP+ reductase activity
ABC_RS15820	COG2124	cytochrome p450
ABC_RS15830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABC_RS15830	COG0140	phosphoribosyl-ATP diphosphatase activity
ABC_RS15835	COG0107	imidazoleglycerol-phosphate synthase activity
ABC_RS15840	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABC_RS15845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABC_RS15850	COG0131	Imidazoleglycerol-phosphate dehydratase
ABC_RS15855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABC_RS15860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABC_RS15865	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABC_RS15870	COG0110	maltose O-acetyltransferase activity
ABC_RS15875	COG0546	phosphoglycolate phosphatase activity
ABC_RS15880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABC_RS15885	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABC_RS15890	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ABC_RS15895	COG1950	PFAM Membrane protein of
ABC_RS15905	COG3595	metallopeptidase activity
ABC_RS15910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABC_RS15915	COG0556	nucleotide-excision repair
ABC_RS15930	COG3409	Peptidoglycan-binding domain 1 protein
ABC_RS15930	COG0793	Belongs to the peptidase S41A family
ABC_RS15935	COG0739	heme binding
ABC_RS15940	COG2177	Part of the ABC transporter FtsEX involved in
ABC_RS15945	COG2884	Cell division ATP-binding protein ftsE
ABC_RS15950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABC_RS15955	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABC_RS15960	COG0653	protein targeting
ABC_RS15965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABC_RS15970	COG1278	Cold shock
ABC_RS15985	COG1516	flagellar protein fliS
ABC_RS15990	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ABC_RS16000	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ABC_RS16005	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ABC_RS16010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC_RS16015	COG4786	Flagellar basal body rod
ABC_RS16015	COG1256	bacterial-type flagellum assembly
ABC_RS16025	COG2747	anti-sigma28 factor FlgM
ABC_RS16040	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ABC_RS16045	COG1307	EDD domain protein, DegV family
ABC_RS16060	COG1739	Uncharacterized protein family UPF0029
ABC_RS16065	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ABC_RS16070	COG4166	transmembrane transport
ABC_RS16080	COG0601	transmembrane transport
ABC_RS16085	COG4608	Belongs to the ABC transporter superfamily
ABC_RS16100	COG1316	TRANSCRIPTIONal
ABC_RS16105	COG4193	domain, Protein
ABC_RS16110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABC_RS16115	COG1215	transferase activity, transferring glycosyl groups
ABC_RS16115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABC_RS16120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABC_RS16120	COG0463	Glycosyl transferase, family 2
ABC_RS16125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABC_RS16135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABC_RS16140	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC_RS16145	COG1215	transferase activity, transferring glycosyl groups
ABC_RS16155	COG1780	Probably involved in ribonucleotide reductase function
ABC_RS16160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABC_RS16165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABC_RS16170	COG4112	unkown
ABC_RS16175	COG1335	isochorismatase
ABC_RS16185	COG3858	chitin binding
ABC_RS16185	COG1388	LysM domain
ABC_RS16190	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS16200	COG1621	beta-fructofuranosidase activity
ABC_RS16210	COG0395	ABC-type sugar transport system, permease component
ABC_RS16215	COG4209	transmembrane transport
ABC_RS16220	COG1609	Transcriptional regulator
ABC_RS16230	COG3842	ATPase activity
ABC_RS16235	COG0395	ABC-type sugar transport system, permease component
ABC_RS16240	COG1175	transmembrane transport
ABC_RS16250	COG1472	Belongs to the glycosyl hydrolase 3 family
ABC_RS16260	COG1396	sequence-specific DNA binding
ABC_RS16280	COG1725	Transcriptional regulator
ABC_RS16285	COG1131	(ABC) transporter
ABC_RS16300	COG0800	Aldolase
ABC_RS16310	COG1959	2 iron, 2 sulfur cluster binding
ABC_RS16315	COG2112	serine threonine protein kinase
ABC_RS16325	COG4585	Histidine kinase
ABC_RS16325	COG2203	Gaf domain
ABC_RS16330	COG2197	response regulator
ABC_RS16340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABC_RS16345	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS16355	COG2378	regulation of single-species biofilm formation
ABC_RS16360	COG2318	DinB family
ABC_RS16365	COG0561	phosphatase activity
ABC_RS16370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABC_RS16375	COG0673	inositol 2-dehydrogenase activity
ABC_RS16380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABC_RS16385	COG2169	Transcriptional regulator
ABC_RS16390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABC_RS16445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABC_RS16450	COG1215	transferase activity, transferring glycosyl groups
ABC_RS16460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ABC_RS16475	COG0438	transferase activity, transferring glycosyl groups
ABC_RS16520	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ABC_RS16525	COG1473	amidohydrolase
ABC_RS16550	COG1131	(ABC) transporter
ABC_RS16555	COG0842	Transport permease protein
ABC_RS16560	COG1309	transcriptional regulator
ABC_RS16565	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABC_RS16570	COG0583	DNA-binding transcription factor activity
ABC_RS16585	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABC_RS16600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS16600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS16600	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS16605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS16605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABC_RS16605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS16610	COG1105	Belongs to the carbohydrate kinase PfkB family
ABC_RS16655	COG1177	transmembrane transport
ABC_RS16660	COG3842	ATPase activity
ABC_RS16665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABC_RS16685	COG0395	ABC-type sugar transport system, permease component
ABC_RS16700	COG0516	GMP reductase activity
ABC_RS16705	COG1368	sulfuric ester hydrolase activity
ABC_RS16715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ABC_RS16720	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ABC_RS16725	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ABC_RS16735	COG2814	Major facilitator Superfamily
ABC_RS16740	COG4187	Peptidase family M20/M25/M40
ABC_RS16745	COG1940	carbohydrate kinase activity
ABC_RS16755	COG0745	RESPONSE REGULATOR receiver
ABC_RS16760	COG5002	protein histidine kinase activity
ABC_RS16765	COG1136	(ABC) transporter
ABC_RS16770	COG0577	efflux transmembrane transporter activity
ABC_RS16775	COG2217	Heavy metal translocating P-type atpase
ABC_RS16795	COG3732	PTS system glucitol sorbitol-specific
ABC_RS16800	COG3730	PTS system glucitol sorbitol-specific
ABC_RS16815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS16830	COG1846	Transcriptional regulator
ABC_RS16835	COG0456	acetyltransferase
ABC_RS16850	COG1116	anion transmembrane transporter activity
ABC_RS16855	COG0247	lactate metabolic process
ABC_RS16860	COG0277	FAD linked oxidase domain protein
ABC_RS16865	COG3835	regulator
ABC_RS16870	COG2270	Major facilitator Superfamily
ABC_RS16875	COG1968	undecaprenyl-diphosphatase activity
ABC_RS16885	COG1482	cell wall glycoprotein biosynthetic process
ABC_RS16895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABC_RS16920	COG1177	transmembrane transport
ABC_RS16925	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC_RS16930	COG3842	ATPase activity
ABC_RS16935	COG0583	DNA-binding transcription factor activity
ABC_RS16950	COG1309	transcriptional regulator
ABC_RS16960	COG3420	alginic acid biosynthetic process
ABC_RS16970	COG3328	transposase activity
ABC_RS16985	COG0395	ABC-type sugar transport system, permease component
ABC_RS16995	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ABC_RS17005	COG0673	inositol 2-dehydrogenase activity
ABC_RS17015	COG2207	Transcriptional regulator
ABC_RS17015	COG3708	Transcriptional regulator
ABC_RS17025	COG0395	ABC-type sugar transport system, permease component
ABC_RS17030	COG1175	transmembrane transport
ABC_RS17035	COG1653	transport
ABC_RS17040	COG0673	inositol 2-dehydrogenase activity
ABC_RS17050	COG2207	Transcriptional regulator
ABC_RS17050	COG1917	Cupin 2, conserved barrel domain protein
ABC_RS17055	COG0673	inositol 2-dehydrogenase activity
ABC_RS17065	COG0384	phenazine biosynthesis protein PhzF
ABC_RS17085	COG1368	sulfuric ester hydrolase activity
ABC_RS17095	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC_RS17095	COG2247	cell wall binding repeat
ABC_RS17100	COG5504	Zn-dependent protease
ABC_RS17105	COG0501	Belongs to the peptidase M48B family
ABC_RS17115	COG0395	ABC-type sugar transport system, permease component
ABC_RS17125	COG1653	transport
ABC_RS17145	COG0456	acetyltransferase
ABC_RS17155	COG2261	transglycosylase associated protein
ABC_RS17165	COG0124	histidyl-tRNA synthetase
ABC_RS17170	COG1418	mRNA catabolic process
ABC_RS17195	COG1309	transcriptional regulator
ABC_RS17220	COG1078	dGTPase activity
ABC_RS17230	COG0457	Tetratricopeptide repeat
ABC_RS17250	COG3314	Sporulation integral membrane protein YlbJ
ABC_RS17255	COG0402	S-adenosylhomocysteine deaminase activity
ABC_RS17265	COG1228	amidohydrolase
ABC_RS17270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ABC_RS17285	COG4585	Histidine kinase
ABC_RS17290	COG2197	response regulator
ABC_RS17300	COG3711	transcriptional antiterminator
ABC_RS17305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS17305	COG1263	PTS System
ABC_RS17310	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABC_RS17315	COG1388	LysM domain
ABC_RS17325	COG0488	(ABC) transporter
ABC_RS17330	COG1063	alcohol dehydrogenase
ABC_RS17335	COG1063	alcohol dehydrogenase
ABC_RS17340	COG3775	system Galactitol-specific IIC component
ABC_RS17345	COG3414	Phosphotransferase system galactitol-specific IIB component
ABC_RS17360	COG2217	Heavy metal translocating P-type atpase
ABC_RS17370	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ABC_RS17380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABC_RS17385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABC_RS17390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC_RS17400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC_RS17405	COG1609	Transcriptional regulator
ABC_RS17435	COG1694	Mazg nucleotide pyrophosphohydrolase
ABC_RS17440	COG1134	teichoic acid transport
ABC_RS17445	COG1682	transport, permease protein
ABC_RS17455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABC_RS17460	COG3507	Belongs to the glycosyl hydrolase 43 family
ABC_RS17470	COG3534	alpha-L-arabinofuranosidase
ABC_RS17475	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABC_RS17480	COG4149	molybdate abc transporter
ABC_RS17485	COG2197	response regulator
ABC_RS17490	COG4585	Histidine kinase
ABC_RS17525	COG1609	Transcriptional regulator
ABC_RS17530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ABC_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS17550	COG2032	superoxide dismutase activity
ABC_RS17555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABC_RS17565	COG0640	Transcriptional regulator
ABC_RS17570	COG0583	DNA-binding transcription factor activity
ABC_RS17575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABC_RS17580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC_RS17585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABC_RS17590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC_RS17595	COG1116	anion transmembrane transporter activity
ABC_RS17605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABC_RS17610	COG0431	NADPH-dependent FMN reductase
ABC_RS17615	COG0583	DNA-binding transcription factor activity
ABC_RS17625	COG2323	membrane
ABC_RS17640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABC_RS17645	COG1309	transcriptional regulator
ABC_RS17655	COG1131	(ABC) transporter
ABC_RS17670	COG1587	Uroporphyrinogen-III synthase
ABC_RS17675	COG1063	alcohol dehydrogenase
ABC_RS17680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABC_RS17685	COG3546	catalase activity
ABC_RS17695	COG2113	Glycine betaine
ABC_RS17700	COG1253	flavin adenine dinucleotide binding
ABC_RS17705	COG4509	Sortase family
ABC_RS17710	COG1120	ATPase activity
ABC_RS17730	COG5386	Cell surface protein
ABC_RS17735	COG2329	Antibiotic biosynthesis monooxygenase
ABC_RS17750	COG1063	alcohol dehydrogenase
ABC_RS17755	COG2226	methyltransferase
ABC_RS17760	COG1309	transcriptional regulator
ABC_RS17765	COG0477	Major facilitator Superfamily
ABC_RS17780	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS17790	COG0596	Alpha beta hydrolase
ABC_RS17800	COG0673	inositol 2-dehydrogenase activity
ABC_RS17805	COG0673	inositol 2-dehydrogenase activity
ABC_RS17810	COG0395	ABC-type sugar transport system, permease component
ABC_RS17815	COG1175	transmembrane transport
ABC_RS17825	COG1940	carbohydrate kinase activity
ABC_RS17830	COG2311	Membrane
ABC_RS17855	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABC_RS17860	COG0542	response to heat
ABC_RS17890	COG2135	peptidase activity
ABC_RS17905	COG2720	vancomycin resistance protein
ABC_RS17930	COG1366	Belongs to the anti-sigma-factor antagonist family
ABC_RS17950	COG2197	response regulator
ABC_RS17965	COG1082	Xylose isomerase domain protein TIM barrel
ABC_RS17970	COG0395	ABC-type sugar transport system, permease component
ABC_RS17985	COG0673	inositol 2-dehydrogenase activity
ABC_RS17990	COG1609	Transcriptional regulator
ABC_RS18000	COG2207	Transcriptional regulator
ABC_RS18005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC_RS18015	COG1609	Transcriptional regulator
ABC_RS18020	COG0840	transmembrane signaling receptor activity
ABC_RS18030	COG2602	Beta-lactamase
ABC_RS18045	COG2819	hydrolase of the alpha beta superfamily
ABC_RS18050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC_RS18055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABC_RS18060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC_RS18065	COG2207	Transcriptional regulator
ABC_RS18065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABC_RS18085	COG0697	spore germination
ABC_RS18090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABC_RS18100	COG0577	efflux transmembrane transporter activity
ABC_RS18105	COG1136	(ABC) transporter
ABC_RS18110	COG1653	transport
ABC_RS18120	COG0395	ABC-type sugar transport system, permease component
ABC_RS18135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABC_RS18160	COG0693	protein deglycase activity
ABC_RS18180	COG0789	Transcriptional regulator
ABC_RS18185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABC_RS18190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC_RS18210	COG1874	Beta-galactosidase
ABC_RS18220	COG3833	ABC-type maltose transport systems, permease component
ABC_RS18225	COG1175	transmembrane transport
ABC_RS18230	COG2182	Extracellular solute-binding protein
ABC_RS18235	COG1609	Transcriptional regulator
ABC_RS18260	COG0697	spore germination
ABC_RS18265	COG1378	Sugar-specific transcriptional regulator TrmB
ABC_RS18275	COG1131	(ABC) transporter
ABC_RS18280	COG2207	Transcriptional regulator
ABC_RS18295	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS18305	COG2312	Erythromycin esterase
ABC_RS18310	COG1376	ErfK ybiS ycfS ynhG family protein
ABC_RS18340	COG0300	oxidoreductase activity
ABC_RS18355	COG1879	ABC-type sugar transport system periplasmic component
ABC_RS18360	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABC_RS18365	COG1129	ABC transporter
ABC_RS18370	COG1869	D-ribose catabolic process
ABC_RS18375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC_RS18380	COG1609	Transcriptional regulator
ABC_RS18395	COG5002	protein histidine kinase activity
ABC_RS18395	COG3850	Histidine kinase
ABC_RS18400	COG0745	RESPONSE REGULATOR receiver
ABC_RS18415	COG1131	(ABC) transporter
ABC_RS18440	COG1132	(ABC) transporter
ABC_RS18455	COG1396	sequence-specific DNA binding
ABC_RS18475	COG1063	alcohol dehydrogenase
ABC_RS18480	COG3775	system Galactitol-specific IIC component
ABC_RS18485	COG3414	Phosphotransferase system galactitol-specific IIB component
ABC_RS18495	COG1349	DNA-binding transcription factor activity
ABC_RS18525	COG1737	Transcriptional regulator
ABC_RS18530	COG1263	PTS System
ABC_RS18530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS18540	COG0445	tRNA wobble uridine modification
ABC_RS18545	COG0395	ABC-type sugar transport system, permease component
ABC_RS18550	COG1175	transmembrane transport
ABC_RS18555	COG1653	transport
ABC_RS18560	COG2972	Histidine kinase
ABC_RS18565	COG4753	response regulator
ABC_RS18565	COG2207	Transcriptional regulator
ABC_RS18580	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ABC_RS18585	COG1518	maintenance of DNA repeat elements
ABC_RS18615	COG1794	racemase activity, acting on amino acids and derivatives
ABC_RS18635	COG4682	membrane
ABC_RS18640	COG1609	Transcriptional regulator
ABC_RS18645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC_RS18665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABC_RS18670	COG1494	fructose-1,6-bisphosphatase
ABC_RS18675	COG2376	Dihydroxyacetone kinase
ABC_RS18680	COG2376	Dihydroxyacetone kinase
ABC_RS18685	COG0698	ribose 5-phosphate isomerase
ABC_RS18690	COG1349	DNA-binding transcription factor activity
ABC_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS18700	COG1063	alcohol dehydrogenase
ABC_RS18705	COG2814	Major facilitator Superfamily
ABC_RS18720	COG0318	PFAM AMP-dependent synthetase and ligase
ABC_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS18735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC_RS18735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC_RS18740	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC_RS18745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC_RS18765	COG3546	catalase activity
ABC_RS18780	COG0402	S-adenosylhomocysteine deaminase activity
ABC_RS18785	COG1733	regulation of RNA biosynthetic process
ABC_RS18790	COG1741	Belongs to the pirin family
ABC_RS18835	COG1131	(ABC) transporter
ABC_RS18840	COG0745	RESPONSE REGULATOR receiver
ABC_RS18845	COG2205	protein histidine kinase activity
ABC_RS18850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABC_RS18855	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ABC_RS18865	COG2207	Transcriptional regulator
ABC_RS18865	COG4753	response regulator
ABC_RS18870	COG2972	Histidine kinase
ABC_RS18880	COG3842	ATPase activity
ABC_RS18885	COG1840	ABC-type Fe3 transport system, periplasmic component
ABC_RS18900	COG1473	amidohydrolase
ABC_RS18910	COG0471	metal ion transport
ABC_RS18915	COG1473	amidohydrolase
ABC_RS18920	COG4608	Belongs to the ABC transporter superfamily
ABC_RS18925	COG0444	Belongs to the ABC transporter superfamily
ABC_RS18930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABC_RS18935	COG0601	transmembrane transport
ABC_RS18940	COG0747	negative chemotaxis
ABC_RS18950	COG0583	DNA-binding transcription factor activity
ABC_RS18955	COG2971	BadF BadG BcrA BcrD
ABC_RS18965	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABC_RS18970	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC_RS18970	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABC_RS18985	COG1486	melibiose metabolic process
ABC_RS19045	COG1733	regulation of RNA biosynthetic process
ABC_RS19050	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABC_RS19070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ABC_RS19075	COG2244	polysaccharide biosynthetic process
ABC_RS19080	COG1091	dTDP-4-dehydrorhamnose reductase activity
ABC_RS19095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ABC_RS19120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABC_RS19125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABC_RS19130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABC_RS19150	COG0814	amino acid
ABC_RS19155	COG0697	spore germination
ABC_RS19175	COG1028	Short-chain dehydrogenase reductase Sdr
ABC_RS19180	COG1115	amino acid carrier protein
ABC_RS19185	COG4122	O-methyltransferase activity
ABC_RS19190	COG0583	DNA-binding transcription factor activity
ABC_RS19195	COG0640	Transcriptional regulator
ABC_RS19200	COG5658	integral membrane protein
ABC_RS19225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC_RS19230	COG1116	anion transmembrane transporter activity
ABC_RS19235	COG0693	protein deglycase activity
ABC_RS19290	COG3361	conserved protein (COG2071)
ABC_RS19295	COG0154	amidase activity
ABC_RS19300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABC_RS19305	COG1288	antiporter activity
ABC_RS19315	COG3648	Uricase
ABC_RS19315	COG3195	allantoin biosynthetic process
ABC_RS19325	COG2508	Transcriptional regulator
ABC_RS19330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC_RS19335	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABC_RS19340	COG2080	2 iron, 2 sulfur cluster binding
ABC_RS19345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABC_RS19360	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ABC_RS19370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC_RS19390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABC_RS19395	COG1116	anion transmembrane transporter activity
ABC_RS19410	COG0537	adenosine 5'-monophosphoramidase activity
ABC_RS19415	COG1959	2 iron, 2 sulfur cluster binding
ABC_RS19440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABC_RS19455	COG0300	oxidoreductase activity
ABC_RS19465	COG1263	PTS System
ABC_RS19465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABC_RS19470	COG1621	beta-fructofuranosidase activity
ABC_RS19475	COG1609	Transcriptional regulator
ABC_RS19480	COG0778	Nitroreductase
ABC_RS19495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABC_RS19500	COG1914	H( )-stimulated, divalent metal cation uptake system
ABC_RS19505	COG1984	allophanate hydrolase subunit 2
ABC_RS19510	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABC_RS19520	COG1175	transmembrane transport
ABC_RS19525	COG0395	ABC-type sugar transport system, permease component
ABC_RS19570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABC_RS19580	COG2910	NAD(P)H-binding
ABC_RS19585	COG1959	2 iron, 2 sulfur cluster binding
ABC_RS19600	COG3711	transcriptional antiterminator
ABC_RS19605	COG2723	6-phospho-beta-galactosidase activity
ABC_RS19725	COG4464	protein tyrosine phosphatase activity
ABC_RS19730	COG0489	protein tyrosine kinase activity
ABC_RS19735	COG3944	biosynthesis protein
ABC_RS19740	COG1316	TRANSCRIPTIONal
ABC_RS19750	COG0590	tRNA wobble adenosine to inosine editing
ABC_RS19755	COG0537	adenosine 5'-monophosphoramidase activity
ABC_RS19760	COG0772	Belongs to the SEDS family
ABC_RS19765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABC_RS19770	COG1316	TRANSCRIPTIONal
ABC_RS19775	COG2388	GCN5-related N-acetyl-transferase
ABC_RS19785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABC_RS19790	COG1388	LysM domain
ABC_RS19790	COG0791	NLP P60 protein
ABC_RS19800	COG2318	DinB family
ABC_RS19815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ABC_RS19825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABC_RS19850	COG4786	Flagellar basal body rod
ABC_RS19855	COG4786	Flagellar basal body rod
ABC_RS19860	COG1077	Cell shape determining protein MreB Mrl
ABC_RS19865	COG1609	Transcriptional regulator
ABC_RS19870	COG2076	Multidrug Resistance protein
ABC_RS19875	COG2076	Multidrug Resistance protein
ABC_RS19880	COG0739	heme binding
ABC_RS19885	COG2385	sporulation resulting in formation of a cellular spore
ABC_RS19890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC_RS19905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ABC_RS19910	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABC_RS19915	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABC_RS19920	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ABC_RS19925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC_RS19930	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ABC_RS19935	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABC_RS19940	COG0356	it plays a direct role in the translocation of protons across the membrane
ABC_RS19955	COG1404	Belongs to the peptidase S8 family
ABC_RS19965	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABC_RS19970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABC_RS19975	COG4475	Protein of unknown function (DUF436)
ABC_RS19980	COG0698	ribose 5-phosphate isomerase
ABC_RS19995	COG1971	Probably functions as a manganese efflux pump
ABC_RS20005	COG0009	L-threonylcarbamoyladenylate synthase
ABC_RS20025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABC_RS20030	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABC_RS20040	COG1435	thymidine kinase activity
ABC_RS20045	COG0254	rRNA binding
ABC_RS20050	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABC_RS20055	COG1494	fructose-1,6-bisphosphatase
ABC_RS20060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABC_RS20065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABC_RS20070	COG0191	fructose-bisphosphate aldolase activity
ABC_RS20085	COG0504	CTP synthase activity
ABC_RS20090	COG3343	RNA polymerase activity
ABC_RS20100	COG1960	acyl-CoA dehydrogenase activity
ABC_RS20105	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABC_RS20110	COG0183	Belongs to the thiolase family
ABC_RS20115	COG2181	nitrate reductase activity
ABC_RS20115	COG0247	lactate metabolic process
ABC_RS20120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABC_RS20125	COG2839	Protein conserved in bacteria
ABC_RS20130	COG0018	arginyl-trna synthetase
ABC_RS20140	COG0010	Belongs to the arginase family
ABC_RS20145	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABC_RS20150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABC_RS20160	COG1164	Oligoendopeptidase f
ABC_RS20175	COG3764	Sortase (surface protein transpeptidase)
ABC_RS20190	COG3465	dGTPase activity
ABC_RS20195	COG1078	dGTPase activity
ABC_RS20200	COG1301	dicarboxylic acid transport
ABC_RS20205	COG0095	Lipoate-protein ligase
ABC_RS20210	COG0280	phosphate acetyltransferase
ABC_RS20215	COG1024	Enoyl-CoA hydratase
ABC_RS20220	COG3253	May function as heme-dependent peroxidase
ABC_RS20225	COG0706	membrane insertase activity
ABC_RS20235	COG1668	transmembrane transport
ABC_RS20240	COG4152	abc transporter atp-binding protein
ABC_RS20245	COG1131	(ABC) transporter
ABC_RS20250	COG2188	Transcriptional regulator
ABC_RS20260	COG3773	Cell wall hydrolase
ABC_RS20270	COG2363	Small membrane protein
ABC_RS20275	COG0456	acetyltransferase
ABC_RS20280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABC_RS20300	COG0004	ammonium transporteR
ABC_RS20310	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABC_RS20315	COG3314	Sporulation integral membrane protein YlbJ
ABC_RS20320	COG0351	phosphomethylpyrimidine kinase
ABC_RS20325	COG2986	histidine ammonia-lyase
ABC_RS20340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS20375	COG0513	Belongs to the DEAD box helicase family
ABC_RS20380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABC_RS20385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABC_RS20390	COG0723	plastoquinol--plastocyanin reductase activity
ABC_RS20390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABC_RS20410	COG0024	Methionine aminopeptidase
ABC_RS20420	COG1785	Belongs to the alkaline phosphatase family
ABC_RS20425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABC_RS20425	COG0551	DNA topoisomerase type I activity
ABC_RS20430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABC_RS20435	COG2814	Major facilitator Superfamily
ABC_RS20450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC_RS20455	COG1321	iron dependent repressor
ABC_RS20455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABC_RS20460	COG1121	(ABC) transporter
ABC_RS20465	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABC_RS20470	COG0561	phosphatase activity
ABC_RS20475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABC_RS20485	COG0840	transmembrane signaling receptor activity
ABC_RS20490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ABC_RS20495	COG2814	Major facilitator Superfamily
ABC_RS20505	COG0753	catalase activity
ABC_RS20510	COG1132	(ABC) transporter
ABC_RS20515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABC_RS20520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABC_RS20525	COG2323	membrane
ABC_RS20530	COG1597	lipid kinase activity
ABC_RS20540	COG0789	Transcriptional regulator
ABC_RS20545	COG5504	Zn-dependent protease
ABC_RS20550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ABC_RS20555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABC_RS20560	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ABC_RS20600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC_RS20600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABC_RS20615	COG2972	Histidine kinase
ABC_RS20615	COG0745	RESPONSE REGULATOR receiver
ABC_RS20635	COG0471	metal ion transport
ABC_RS20640	COG4565	transcriptional regulatory protein
ABC_RS20645	COG3290	protein histidine kinase activity
ABC_RS20650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ABC_RS20665	COG1114	Component of the transport system for branched-chain amino acids
ABC_RS20690	COG0733	neurotransmitter:sodium symporter activity
ABC_RS20695	COG2154	pterin-4-alpha-carbinolamine dehydratase
ABC_RS20715	COG0745	RESPONSE REGULATOR receiver
ABC_RS20725	COG2807	transmembrane transport
ABC_RS20760	COG1307	EDD domain protein, DegV family
ABC_RS20765	COG1193	negative regulation of DNA recombination
ABC_RS20770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABC_RS20775	COG0523	cobalamin synthesis protein
ABC_RS20780	COG0813	purine-nucleoside phosphorylase activity
ABC_RS20785	COG0346	lactoylglutathione lyase activity
ABC_RS20795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABC_RS20800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABC_RS20805	COG2031	fatty acid transporter
ABC_RS20810	COG1609	Transcriptional regulator
ABC_RS20815	COG3833	ABC-type maltose transport systems, permease component
ABC_RS20820	COG1175	transmembrane transport
ABC_RS20825	COG2182	Extracellular solute-binding protein
ABC_RS20840	COG0402	S-adenosylhomocysteine deaminase activity
ABC_RS20845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABC_RS20855	COG2508	Transcriptional regulator
ABC_RS20860	COG0579	oxidoreductase
ABC_RS20865	COG0247	lactate metabolic process
ABC_RS20870	COG0277	FAD linked oxidase domain protein
ABC_RS20875	COG2186	Transcriptional regulator
ABC_RS20880	COG2186	Transcriptional regulator
ABC_RS20895	COG0583	DNA-binding transcription factor activity
ABC_RS20900	COG0372	Belongs to the citrate synthase family
ABC_RS20915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC_RS20920	COG1802	Transcriptional regulator
ABC_RS20925	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABC_RS20940	COG1595	DNA-templated transcription, initiation
ABC_RS20965	COG1966	Carbon starvation protein
ABC_RS20975	COG3275	phosphorelay sensor kinase activity
ABC_RS20995	COG4608	Belongs to the ABC transporter superfamily
ABC_RS21000	COG0444	Belongs to the ABC transporter superfamily
ABC_RS21010	COG0601	transmembrane transport
ABC_RS21035	COG1131	(ABC) transporter
ABC_RS21055	COG3716	PTS system mannose fructose sorbose family IID component
ABC_RS21065	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ABC_RS21065	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ABC_RS21070	COG0235	Class ii aldolase
ABC_RS21075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABC_RS21075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC_RS21080	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ABC_RS21085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABC_RS21090	COG1063	alcohol dehydrogenase
ABC_RS21115	COG2226	methyltransferase
ABC_RS21120	COG0084	hydrolase, TatD family'
ABC_RS21165	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABC_RS21170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABC_RS21175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABC_RS21180	COG4853	Protein conserved in bacteria
ABC_RS21190	COG5002	protein histidine kinase activity
ABC_RS21195	COG0745	RESPONSE REGULATOR receiver
ABC_RS21225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABC_RS21230	COG0305	Participates in initiation and elongation during chromosome replication
ABC_RS21235	COG0359	binds to the 23S rRNA
ABC_RS21240	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ABC_RS21250	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABC_RS21255	COG0629	single-stranded DNA binding
ABC_RS21260	COG0360	Binds together with S18 to 16S ribosomal RNA
ABC_RS21265	COG0012	GTP binding
ABC_RS21270	COG4481	Protein conserved in bacteria
ABC_RS21275	COG3949	Membrane
ABC_RS21285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABC_RS21290	COG1475	DNA binding
ABC_RS21295	COG1192	Involved in chromosome partitioning
ABC_RS21300	COG1475	DNA binding
ABC_RS21305	COG0357	Ribosomal RNA small subunit methyltransferase G
ABC_RS21310	COG0445	tRNA wobble uridine modification
ABC_RS21315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ABC_RS21320	COG1847	R3H domain protein
ABC_RS21325	COG0706	membrane insertase activity
ABC_RS21330	COG0594	ribonuclease P activity
ABC_RS21335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ABC_RS21345	COG0789	Transcriptional regulator
ABC_RS21350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS21355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABC_RS21385	COG3212	peptidase
ABC_RS21400	COG0438	transferase activity, transferring glycosyl groups
ABC_RS21415	COG3835	regulator
ABC_RS21425	COG0746	molybdenum cofactor guanylyltransferase activity
ABC_RS21445	COG4585	Histidine kinase
ABC_RS21490	COG3953	SLT domain
ABC_RS21490	COG5280	Phage tail tape measure protein TP901
ABC_RS21505	COG3290	protein histidine kinase activity
ABC_RS21510	COG1388	LysM domain
ABC_RS21520	COG0366	Alpha amylase catalytic
ABC_RS21530	COG3584	3D domain protein
ABC_RS21530	COG3583	domain protein
ABC_RS21550	COG2201	protein-glutamate methylesterase activity
ABC_RS21565	COG5504	Zn-dependent protease
ABC_RS21570	COG2267	carboxylic ester hydrolase activity
ABC_RS21585	COG5280	Phage tail tape measure protein TP901
ABC_RS21585	COG3953	SLT domain
ABC_RS21605	COG1334	flagellar protein FlaG
ABC_RS21625	COG0589	response to stress
ABC_RS21650	COG5386	Cell surface protein
ABC_RS21690	COG0456	acetyltransferase