locus-tag	class	description
BCO26_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCO26_RS00010	COG0592	DNA-directed DNA polymerase activity
BCO26_RS00015	COG2501	S4 domain
BCO26_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCO26_RS00030	COG0187	DNA topoisomerase II activity
BCO26_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCO26_RS00040	COG3437	response regulator, receiver
BCO26_RS00080	COG1982	Orn Lys Arg decarboxylase major
BCO26_RS00090	COG3870	Protein conserved in bacteria
BCO26_RS00095	COG1728	Protein conserved in bacteria
BCO26_RS00100	COG0470	DNA polymerase III
BCO26_RS00105	COG1774	PSP1 C-terminal conserved region
BCO26_RS00110	COG4467	Involved in initiation control of chromosome replication
BCO26_RS00115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCO26_RS00120	COG2827	Endonuclease containing a URI domain
BCO26_RS00125	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCO26_RS00130	COG2002	toxin-antitoxin pair type II binding
BCO26_RS00140	COG0084	hydrolase, TatD family'
BCO26_RS00160	COG4466	Protein conserved in bacteria
BCO26_RS00170	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCO26_RS00175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCO26_RS00180	COG0251	oxidation-reduction process
BCO26_RS00190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCO26_RS00195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCO26_RS00200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCO26_RS00220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCO26_RS00225	COG2002	toxin-antitoxin pair type II binding
BCO26_RS00230	COG2244	polysaccharide biosynthetic process
BCO26_RS00235	COG3956	TIGRFAM MazG family protein
BCO26_RS00240	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCO26_RS00260	COG1098	S1 RNA binding domain
BCO26_RS00275	COG2208	phosphoserine phosphatase activity
BCO26_RS00285	COG2304	oxidoreductase activity
BCO26_RS00290	COG0515	serine threonine protein kinase
BCO26_RS00295	COG0037	tRNA processing
BCO26_RS00300	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCO26_RS00305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCO26_RS00310	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCO26_RS00315	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCO26_RS00325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCO26_RS00330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCO26_RS00335	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCO26_RS00340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCO26_RS00375	COG0516	GMP reductase activity
BCO26_RS00375	COG0517	IMP dehydrogenase activity
BCO26_RS00390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BCO26_RS00400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCO26_RS00415	COG1428	Deoxynucleoside kinase
BCO26_RS00420	COG1428	Deoxynucleoside kinase
BCO26_RS00425	COG1388	LysM domain
BCO26_RS00425	COG3858	chitin binding
BCO26_RS00430	COG0590	tRNA wobble adenosine to inosine editing
BCO26_RS00435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCO26_RS00440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCO26_RS00445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCO26_RS00490	COG3880	PFAM UvrB UvrC protein
BCO26_RS00495	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BCO26_RS00500	COG0542	response to heat
BCO26_RS00505	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCO26_RS00510	COG4956	integral membrane protein (PIN domain superfamily)
BCO26_RS00520	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCO26_RS00525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCO26_RS00530	COG1045	serine acetyltransferase
BCO26_RS00535	COG0215	cysteine-tRNA ligase activity
BCO26_RS00545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCO26_RS00550	COG3688	RNA-binding protein containing a PIN domain
BCO26_RS00560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCO26_RS00565	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCO26_RS00570	COG0250	Participates in transcription elongation, termination and antitermination
BCO26_RS00575	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCO26_RS00580	COG0081	regulation of translation
BCO26_RS00585	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCO26_RS00595	COG2813	Specifically methylates the guanine in position
BCO26_RS00600	COG0085	RNA polymerase activity
BCO26_RS00610	COG1358	cellular component organization or biogenesis
BCO26_RS00615	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCO26_RS00620	COG0049	tRNA binding
BCO26_RS00625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCO26_RS00630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCO26_RS00640	COG0051	transcription antitermination factor activity, RNA binding
BCO26_RS00660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCO26_RS00665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCO26_RS00675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCO26_RS00680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCO26_RS00685	COG0255	Belongs to the universal ribosomal protein uL29 family
BCO26_RS00690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCO26_RS00695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCO26_RS00705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCO26_RS00710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCO26_RS00715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCO26_RS00720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCO26_RS00725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCO26_RS00730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCO26_RS00740	COG0200	Binds to the 23S rRNA
BCO26_RS00745	COG0201	protein transport
BCO26_RS00750	COG0563	adenylate kinase activity
BCO26_RS00755	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCO26_RS00760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCO26_RS00765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCO26_RS00770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCO26_RS00775	COG0202	RNA polymerase activity
BCO26_RS00780	COG0203	ribosomal protein L17
BCO26_RS00785	COG1122	ATPase activity
BCO26_RS00790	COG1122	ATPase activity
BCO26_RS00795	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCO26_RS00805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCO26_RS00810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCO26_RS00820	COG2046	Belongs to the sulfate adenylyltransferase family
BCO26_RS00825	COG0529	Catalyzes the synthesis of activated sulfate
BCO26_RS00830	COG0833	amino acid
BCO26_RS00840	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCO26_RS00845	COG0489	protein tyrosine kinase activity
BCO26_RS00860	COG2194	sulfuric ester hydrolase activity
BCO26_RS00890	COG0726	polysaccharide deacetylase
BCO26_RS00900	COG1271	oxidase subunit
BCO26_RS00905	COG1294	oxidase, subunit
BCO26_RS00910	COG4988	ABC transporter
BCO26_RS00915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCO26_RS01005	COG1595	DNA-templated transcription, initiation
BCO26_RS01010	COG5662	AntiSigma factor
BCO26_RS01015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCO26_RS01020	COG4856	YbbR-like protein
BCO26_RS01025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCO26_RS01030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCO26_RS01055	COG2814	Major facilitator Superfamily
BCO26_RS01060	COG0583	DNA-binding transcription factor activity
BCO26_RS01065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCO26_RS01070	COG0840	transmembrane signaling receptor activity
BCO26_RS01085	COG1695	Transcriptional regulator
BCO26_RS01090	COG0840	transmembrane signaling receptor activity
BCO26_RS01105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCO26_RS01130	COG3425	synthase
BCO26_RS01135	COG0183	Belongs to the thiolase family
BCO26_RS01155	COG1125	glycine betaine transport
BCO26_RS01155	COG0517	IMP dehydrogenase activity
BCO26_RS01160	COG1174	glycine betaine transport
BCO26_RS01165	COG2190	(PTS) system
BCO26_RS01170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCO26_RS01170	COG1263	PTS System
BCO26_RS01175	COG0366	Alpha amylase catalytic
BCO26_RS01180	COG2188	Transcriptional regulator
BCO26_RS01195	COG1070	Carbohydrate kinase
BCO26_RS01205	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCO26_RS01215	COG0716	FMN binding
BCO26_RS01220	COG0322	excinuclease ABC activity
BCO26_RS01225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCO26_RS01230	COG2217	Heavy metal translocating P-type atpase
BCO26_RS01235	COG2217	Heavy metal translocating P-type atpase
BCO26_RS01240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCO26_RS01250	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCO26_RS01255	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCO26_RS01260	COG1215	transferase activity, transferring glycosyl groups
BCO26_RS01280	COG2076	Multidrug Resistance protein
BCO26_RS01285	COG2076	Multidrug Resistance protein
BCO26_RS01295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCO26_RS01300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCO26_RS01305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCO26_RS01315	COG1120	ATPase activity
BCO26_RS01340	COG0217	transcriptional regulatory protein
BCO26_RS01345	COG1366	Belongs to the anti-sigma-factor antagonist family
BCO26_RS01355	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS01365	COG5434	Belongs to the glycosyl hydrolase 28 family
BCO26_RS01370	COG0175	sulfate reduction
BCO26_RS01395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCO26_RS01400	COG0371	Dehydrogenase
BCO26_RS01405	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS01420	COG0697	spore germination
BCO26_RS01440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCO26_RS01445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BCO26_RS01470	COG0702	epimerase
BCO26_RS01480	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCO26_RS01480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCO26_RS01485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCO26_RS01505	COG2848	UPF0210 protein
BCO26_RS01510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCO26_RS01520	COG5577	PFAM Coat F domain
BCO26_RS01525	COG0667	Aldo Keto reductase
BCO26_RS01535	COG1113	amino acid transport
BCO26_RS01540	COG3104	oligopeptide transport
BCO26_RS01545	COG0833	amino acid
BCO26_RS01555	COG3842	ATPase activity
BCO26_RS01560	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCO26_RS01565	COG1177	transmembrane transport
BCO26_RS01580	COG0531	amino acid
BCO26_RS01585	COG1556	Lactate utilization protein
BCO26_RS01590	COG1139	Iron-sulfur cluster binding protein
BCO26_RS01595	COG0247	lactate metabolic process
BCO26_RS01600	COG0531	amino acid
BCO26_RS01605	COG1979	alcohol dehydrogenase
BCO26_RS01610	COG0004	ammonium transporteR
BCO26_RS01615	COG3290	protein histidine kinase activity
BCO26_RS01620	COG4565	transcriptional regulatory protein
BCO26_RS01625	COG2851	Citrate transporter
BCO26_RS01630	COG0463	Glycosyl transferase, family 2
BCO26_RS01635	COG3973	AAA domain
BCO26_RS01645	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCO26_RS01655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCO26_RS01660	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCO26_RS01665	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCO26_RS01670	COG1301	dicarboxylic acid transport
BCO26_RS01675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCO26_RS01700	COG1902	pentaerythritol trinitrate reductase activity
BCO26_RS01720	COG0423	glycine-tRNA ligase activity
BCO26_RS01735	COG0531	amino acid
BCO26_RS01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCO26_RS01750	COG0628	permease
BCO26_RS01765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCO26_RS01770	COG0765	amino acid transport
BCO26_RS01775	COG0765	amino acid transport
BCO26_RS01790	COG1733	regulation of RNA biosynthetic process
BCO26_RS01795	COG0586	Pfam SNARE associated Golgi protein
BCO26_RS01800	COG0586	Pfam SNARE associated Golgi protein
BCO26_RS01825	COG0646	methionine synthase
BCO26_RS01825	COG1410	methionine synthase
BCO26_RS01850	COG3944	biosynthesis protein
BCO26_RS01855	COG0489	protein tyrosine kinase activity
BCO26_RS01860	COG4464	protein tyrosine phosphatase activity
BCO26_RS01865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCO26_RS01875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCO26_RS01890	COG0438	transferase activity, transferring glycosyl groups
BCO26_RS01900	COG1442	glycosyl transferase family 8
BCO26_RS01900	COG1216	Glycosyl transferase, family 2
BCO26_RS01935	COG1091	dTDP-4-dehydrorhamnose reductase activity
BCO26_RS01945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCO26_RS01990	COG1070	Carbohydrate kinase
BCO26_RS02020	COG1070	Carbohydrate kinase
BCO26_RS02030	COG1940	carbohydrate kinase activity
BCO26_RS02035	COG1063	alcohol dehydrogenase
BCO26_RS02040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BCO26_RS02065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BCO26_RS02075	COG5504	Zn-dependent protease
BCO26_RS02090	COG5263	repeat protein
BCO26_RS02090	COG0366	Alpha amylase catalytic
BCO26_RS02115	COG2315	Protein conserved in bacteria
BCO26_RS02125	COG2333	competence protein COMEC
BCO26_RS02125	COG0658	competence protein
BCO26_RS02135	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BCO26_RS02150	COG0531	amino acid
BCO26_RS02155	COG1316	TRANSCRIPTIONal
BCO26_RS02165	COG4989	oxidoreductase activity
BCO26_RS02180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BCO26_RS02185	COG2130	NADP-dependent
BCO26_RS02205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCO26_RS02205	COG3711	transcriptional antiterminator
BCO26_RS02210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCO26_RS02215	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCO26_RS02225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCO26_RS02230	COG2190	(PTS) system
BCO26_RS02230	COG2211	Major facilitator Superfamily
BCO26_RS02260	COG2814	Major facilitator Superfamily
BCO26_RS02270	COG1609	Transcriptional regulator
BCO26_RS02290	COG1732	Glycine betaine
BCO26_RS02295	COG1174	glycine betaine transport
BCO26_RS02300	COG0517	IMP dehydrogenase activity
BCO26_RS02300	COG1125	glycine betaine transport
BCO26_RS02305	COG1510	regulation of RNA biosynthetic process
BCO26_RS02310	COG0110	maltose O-acetyltransferase activity
BCO26_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS02330	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS02345	COG4297	protein containing double-stranded beta helix domain
BCO26_RS02360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCO26_RS02365	COG2272	Belongs to the type-B carboxylesterase lipase family
BCO26_RS02370	COG0606	chelatase, subunit chli
BCO26_RS02380	COG0371	Dehydrogenase
BCO26_RS02390	COG0157	Belongs to the NadC ModD family
BCO26_RS02395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCO26_RS02400	COG1104	cysteine desulfurase activity
BCO26_RS02410	COG2116	formate transmembrane transporter activity
BCO26_RS02425	COG4720	Psort location CytoplasmicMembrane, score
BCO26_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS02440	COG2610	gluconate transmembrane transporter activity
BCO26_RS02450	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS02460	COG3290	protein histidine kinase activity
BCO26_RS02460	COG3829	transcription factor binding
BCO26_RS02485	COG0584	glycerophosphoryl diester phosphodiesterase
BCO26_RS02490	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS02515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCO26_RS02520	COG0737	Belongs to the 5'-nucleotidase family
BCO26_RS02525	COG1363	Peptidase, m42
BCO26_RS02535	COG1620	l-lactate permease
BCO26_RS02540	COG2186	Transcriptional regulator
BCO26_RS02570	COG0473	3-isopropylmalate dehydrogenase activity
BCO26_RS02605	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCO26_RS02620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCO26_RS02620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCO26_RS02625	COG2723	6-phospho-beta-galactosidase activity
BCO26_RS02630	COG3711	transcriptional antiterminator
BCO26_RS02630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCO26_RS02635	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCO26_RS02645	COG0626	cystathionine gamma-synthase activity
BCO26_RS02650	COG0626	cystathionine gamma-synthase activity
BCO26_RS02670	COG1653	transport
BCO26_RS02675	COG2207	Transcriptional regulator
BCO26_RS02690	COG0604	alcohol dehydrogenase
BCO26_RS02695	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCO26_RS02700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCO26_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS02730	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCO26_RS02740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCO26_RS02750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCO26_RS02755	COG1316	TRANSCRIPTIONal
BCO26_RS02760	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BCO26_RS02765	COG2801	Transposase and inactivated derivatives
BCO26_RS02770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCO26_RS02775	COG1554	hydrolase, family 65, central catalytic
BCO26_RS02785	COG1609	Transcriptional regulator
BCO26_RS02800	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BCO26_RS02815	COG1388	LysM domain
BCO26_RS02815	COG3584	3D domain protein
BCO26_RS02825	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCO26_RS02835	COG0011	TIGRFAM Protein of
BCO26_RS02840	COG2706	6-phosphogluconolactonase activity
BCO26_RS02855	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCO26_RS02855	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCO26_RS02860	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCO26_RS02860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCO26_RS02870	COG3715	PTS system
BCO26_RS02875	COG3716	PTS system mannose fructose sorbose family IID component
BCO26_RS02890	COG2079	MmgE PrpD family protein
BCO26_RS02895	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCO26_RS02905	COG0154	amidase activity
BCO26_RS02920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCO26_RS02925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCO26_RS02930	COG1116	anion transmembrane transporter activity
BCO26_RS02935	COG0083	homoserine kinase activity
BCO26_RS02940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCO26_RS02945	COG0460	homoserine dehydrogenase
BCO26_RS02950	COG0010	Belongs to the arginase family
BCO26_RS02960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCO26_RS02965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCO26_RS02975	COG4145	pantothenate transmembrane transporter activity
BCO26_RS02990	COG1454	alcohol dehydrogenase
BCO26_RS02990	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS03005	COG1388	LysM domain
BCO26_RS03005	COG0791	NLP P60 protein
BCO26_RS03010	COG0024	Methionine aminopeptidase
BCO26_RS03015	COG1268	BioY protein
BCO26_RS03020	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS03025	COG2746	aminoglycoside 3-N-acetyltransferase activity
BCO26_RS03030	COG2244	polysaccharide biosynthetic process
BCO26_RS03035	COG0589	response to stress
BCO26_RS03050	COG0535	radical SAM domain protein
BCO26_RS03060	COG2211	Major facilitator Superfamily
BCO26_RS03065	COG1609	Transcriptional regulator
BCO26_RS03075	COG0561	phosphatase activity
BCO26_RS03100	COG0656	L-ascorbic acid biosynthetic process
BCO26_RS03105	COG0431	NADPH-dependent FMN reductase
BCO26_RS03115	COG0420	3'-5' exonuclease activity
BCO26_RS03120	COG4717	serine-type aminopeptidase activity
BCO26_RS03125	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCO26_RS03130	COG0534	Mate efflux family protein
BCO26_RS03145	COG0789	Transcriptional regulator
BCO26_RS03150	COG0436	Aminotransferase
BCO26_RS03155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCO26_RS03165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCO26_RS03185	COG0798	PFAM Bile acid sodium symporter
BCO26_RS03230	COG2226	methyltransferase
BCO26_RS03245	COG1090	epimerase
BCO26_RS03250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCO26_RS03275	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BCO26_RS03290	COG1960	acyl-CoA dehydrogenase activity
BCO26_RS03305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCO26_RS03310	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BCO26_RS03325	COG1609	Transcriptional regulator
BCO26_RS03345	COG2996	Protein conserved in bacteria
BCO26_RS03350	COG0346	lactoylglutathione lyase activity
BCO26_RS03355	COG1482	cell wall glycoprotein biosynthetic process
BCO26_RS03365	COG0477	Major facilitator Superfamily
BCO26_RS03370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCO26_RS03380	COG2188	Transcriptional regulator
BCO26_RS03385	COG0791	NLP P60 protein
BCO26_RS03385	COG1388	LysM domain
BCO26_RS03395	COG0768	penicillin binding
BCO26_RS03400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCO26_RS03405	COG1739	Uncharacterized protein family UPF0029
BCO26_RS03415	COG2197	response regulator
BCO26_RS03425	COG0531	amino acid
BCO26_RS03430	COG1307	EDD domain protein, DegV family
BCO26_RS03435	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BCO26_RS03440	COG1040	competence protein
BCO26_RS03450	COG2747	anti-sigma28 factor FlgM
BCO26_RS03460	COG1256	bacterial-type flagellum assembly
BCO26_RS03460	COG4786	Flagellar basal body rod
BCO26_RS03465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCO26_RS03475	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCO26_RS03485	COG1067	ATP-dependent peptidase activity
BCO26_RS03495	COG2094	Belongs to the DNA glycosylase MPG family
BCO26_RS03505	COG1334	flagellar protein FlaG
BCO26_RS03510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCO26_RS03515	COG1516	flagellar protein fliS
BCO26_RS03530	COG0405	Gamma-glutamyltransferase
BCO26_RS03540	COG0653	protein targeting
BCO26_RS03545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCO26_RS03550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCO26_RS03560	COG2884	Cell division ATP-binding protein ftsE
BCO26_RS03565	COG2177	Part of the ABC transporter FtsEX involved in
BCO26_RS03570	COG0739	heme binding
BCO26_RS03580	COG2873	o-acetylhomoserine
BCO26_RS03585	COG0460	homoserine dehydrogenase
BCO26_RS03595	COG0793	Belongs to the peptidase S41A family
BCO26_RS03595	COG3409	Peptidoglycan-binding domain 1 protein
BCO26_RS03600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCO26_RS03605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCO26_RS03610	COG4605	iron ion homeostasis
BCO26_RS03615	COG4604	ABC transporter, ATP-binding protein
BCO26_RS03620	COG4607	ABC-type enterochelin transport system periplasmic component
BCO26_RS03635	COG5002	protein histidine kinase activity
BCO26_RS03640	COG0745	RESPONSE REGULATOR receiver
BCO26_RS03660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCO26_RS03675	COG2271	Major facilitator Superfamily
BCO26_RS03685	COG0647	UMP catabolic process
BCO26_RS03690	COG1285	pathogenesis
BCO26_RS03695	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCO26_RS03710	COG0573	inorganic phosphate transmembrane transporter activity
BCO26_RS03715	COG0581	inorganic phosphate transmembrane transporter activity
BCO26_RS03720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCO26_RS03725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCO26_RS03765	COG0556	nucleotide-excision repair
BCO26_RS03770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCO26_RS03775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BCO26_RS03785	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCO26_RS03790	COG1682	transport, permease protein
BCO26_RS03795	COG0463	Glycosyl transferase, family 2
BCO26_RS03795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCO26_RS03800	COG3595	metallopeptidase activity
BCO26_RS03810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BCO26_RS03820	COG0546	phosphoglycolate phosphatase activity
BCO26_RS03825	COG0110	maltose O-acetyltransferase activity
BCO26_RS03830	COG0457	Tetratricopeptide repeat
BCO26_RS03835	COG0492	ferredoxin-NADP+ reductase activity
BCO26_RS03840	COG1051	belongs to the nudix hydrolase family
BCO26_RS03845	COG1660	Displays ATPase and GTPase activities
BCO26_RS03850	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCO26_RS03855	COG1481	regulation of sporulation
BCO26_RS03860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCO26_RS03900	COG3842	ATPase activity
BCO26_RS03910	COG2508	Transcriptional regulator
BCO26_RS03920	COG0189	ligase activity
BCO26_RS03930	COG0189	ligase activity
BCO26_RS03945	COG4399	Belongs to the UPF0754 family
BCO26_RS03955	COG0561	phosphatase activity
BCO26_RS03960	COG1024	Enoyl-CoA hydratase
BCO26_RS03970	COG0861	Integral membrane protein TerC family
BCO26_RS03975	COG0701	Predicted permease
BCO26_RS03980	COG3689	TIGRFAM TIGR03943 family protein
BCO26_RS03985	COG0420	3'-5' exonuclease activity
BCO26_RS03990	COG4717	serine-type aminopeptidase activity
BCO26_RS03995	COG3481	metal-dependent phosphohydrolase, HD sub domain
BCO26_RS04005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCO26_RS04020	COG1846	Transcriptional regulator
BCO26_RS04040	COG0537	adenosine 5'-monophosphoramidase activity
BCO26_RS04045	COG1131	(ABC) transporter
BCO26_RS04050	COG4473	ABC transporter
BCO26_RS04060	COG1473	amidohydrolase
BCO26_RS04065	COG3069	C4-dicarboxylate transmembrane transporter activity
BCO26_RS04075	COG2329	Antibiotic biosynthesis monooxygenase
BCO26_RS04085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCO26_RS04090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCO26_RS04095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCO26_RS04105	COG1309	transcriptional regulator
BCO26_RS04110	COG1511	domain protein
BCO26_RS04115	COG2814	Major facilitator Superfamily
BCO26_RS04120	COG0697	spore germination
BCO26_RS04125	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS04130	COG1999	signal sequence binding
BCO26_RS04140	COG0095	Lipoate-protein ligase
BCO26_RS04145	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS04155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BCO26_RS04165	COG0501	Belongs to the peptidase M48B family
BCO26_RS04175	COG4903	ComK protein
BCO26_RS04190	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BCO26_RS04195	COG1074	ATP-dependent DNA helicase activity
BCO26_RS04230	COG2311	Membrane
BCO26_RS04235	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCO26_RS04255	COG1307	EDD domain protein, DegV family
BCO26_RS04265	COG0561	phosphatase activity
BCO26_RS04270	COG2151	metal-sulfur cluster biosynthetic enzyme
BCO26_RS04305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCO26_RS04310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCO26_RS04330	COG4608	Belongs to the ABC transporter superfamily
BCO26_RS04335	COG0601	transmembrane transport
BCO26_RS04345	COG0747	negative chemotaxis
BCO26_RS04360	COG0180	Tryptophanyl-tRNA synthetase
BCO26_RS04370	COG4166	transmembrane transport
BCO26_RS04375	COG0601	transmembrane transport
BCO26_RS04380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCO26_RS04385	COG0444	Belongs to the ABC transporter superfamily
BCO26_RS04390	COG4608	Belongs to the ABC transporter superfamily
BCO26_RS04395	COG1393	Belongs to the ArsC family
BCO26_RS04405	COG4862	establishment of competence for transformation
BCO26_RS04410	COG4469	Competence protein
BCO26_RS04415	COG1164	Oligoendopeptidase f
BCO26_RS04425	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCO26_RS04430	COG2346	COG2346, Truncated hemoglobins
BCO26_RS04435	COG0741	lytic transglycosylase activity
BCO26_RS04440	COG4116	CYTH
BCO26_RS04450	COG2357	RelA SpoT domain protein
BCO26_RS04460	COG0564	pseudouridine synthase activity
BCO26_RS04465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCO26_RS04470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCO26_RS04505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCO26_RS04530	COG2153	protein acetylation
BCO26_RS04540	COG2382	esterase
BCO26_RS04550	COG1940	carbohydrate kinase activity
BCO26_RS04560	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS04565	COG4152	abc transporter atp-binding protein
BCO26_RS04570	COG1668	transmembrane transport
BCO26_RS04580	COG3579	cysteine-type endopeptidase activity
BCO26_RS04590	COG1247	-acetyltransferase
BCO26_RS04610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCO26_RS04615	COG2059	Chromate
BCO26_RS04620	COG2059	Chromate
BCO26_RS04625	COG1522	sequence-specific DNA binding
BCO26_RS04635	COG0477	Major facilitator Superfamily
BCO26_RS04640	COG0405	Gamma-glutamyltransferase
BCO26_RS04645	COG0154	amidase activity
BCO26_RS04665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCO26_RS04670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCO26_RS04780	COG0477	Major facilitator Superfamily
BCO26_RS04795	COG1959	2 iron, 2 sulfur cluster binding
BCO26_RS04810	COG0730	response to heat
BCO26_RS04815	COG0783	Belongs to the Dps family
BCO26_RS04820	COG0673	inositol 2-dehydrogenase activity
BCO26_RS04825	COG3852	Histidine kinase
BCO26_RS04830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCO26_RS04840	COG0861	Integral membrane protein TerC family
BCO26_RS04860	COG5002	protein histidine kinase activity
BCO26_RS04865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCO26_RS04885	COG0542	response to heat
BCO26_RS04890	COG3949	Membrane
BCO26_RS04905	COG4873	Protein conserved in bacteria
BCO26_RS04920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCO26_RS04935	COG2084	Dehydrogenase
BCO26_RS04940	COG0436	Aminotransferase
BCO26_RS04945	COG0835	chemotaxis
BCO26_RS04945	COG0784	Response regulator, receiver
BCO26_RS04955	COG2409	Drug exporters of the RND superfamily
BCO26_RS04955	COG1033	growth of symbiont in host cell
BCO26_RS04970	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS04980	COG4703	Protein of unknown function (DUF1797)
BCO26_RS04985	COG0517	IMP dehydrogenase activity
BCO26_RS04990	COG0583	DNA-binding transcription factor activity
BCO26_RS04995	COG2171	N-acyltransferase activity
BCO26_RS05000	COG1473	amidohydrolase
BCO26_RS05010	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCO26_RS05045	COG1982	Orn Lys Arg decarboxylase major
BCO26_RS05065	COG0483	inositol monophosphate 1-phosphatase activity
BCO26_RS05075	COG1217	gtp-binding protein TYPA
BCO26_RS05085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCO26_RS05090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCO26_RS05095	COG4838	Belongs to the UPF0358 family
BCO26_RS05100	COG0772	Belongs to the SEDS family
BCO26_RS05105	COG1612	heme a metabolic process
BCO26_RS05110	COG0109	protoheme IX farnesyltransferase activity
BCO26_RS05115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCO26_RS05115	COG2010	Cytochrome c
BCO26_RS05130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCO26_RS05135	COG3336	cytochrome c oxidase
BCO26_RS05145	COG2340	Cysteine-rich secretory protein family
BCO26_RS05170	COG3679	Belongs to the UPF0342 family
BCO26_RS05175	COG4471	UPF0298 protein
BCO26_RS05185	COG0742	ribosomal rna small subunit methyltransferase
BCO26_RS05190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCO26_RS05195	COG3314	Sporulation integral membrane protein YlbJ
BCO26_RS05200	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCO26_RS05205	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCO26_RS05210	COG1323	Belongs to the UPF0348 family
BCO26_RS05220	COG1399	metal-binding, possibly nucleic acid-binding protein
BCO26_RS05225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCO26_RS05235	COG0454	-acetyltransferase
BCO26_RS05240	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCO26_RS05245	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BCO26_RS05250	COG2001	Belongs to the MraZ family
BCO26_RS05255	COG0275	rRNA processing
BCO26_RS05260	COG4839	cell division protein FtsL
BCO26_RS05265	COG0768	penicillin binding
BCO26_RS05270	COG0768	penicillin binding
BCO26_RS05285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCO26_RS05290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCO26_RS05295	COG0772	Belongs to the SEDS family
BCO26_RS05300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCO26_RS05305	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCO26_RS05310	COG0849	cell division
BCO26_RS05315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCO26_RS05325	COG1191	sigma factor activity
BCO26_RS05330	COG1191	sigma factor activity
BCO26_RS05335	COG1873	PFAM PRC-barrel domain
BCO26_RS05340	COG1388	LysM domain
BCO26_RS05340	COG3584	3D domain protein
BCO26_RS05350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCO26_RS05355	COG1799	cell septum assembly
BCO26_RS05360	COG0762	integral membrane protein
BCO26_RS05365	COG2302	S4 RNA-binding domain
BCO26_RS05370	COG3599	regulation of cell shape
BCO26_RS05385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCO26_RS05390	COG0564	pseudouridine synthase activity
BCO26_RS05395	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BCO26_RS05400	COG0540	Belongs to the ATCase OTCase family
BCO26_RS05405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCO26_RS05420	COG0543	2 iron, 2 sulfur cluster binding
BCO26_RS05425	COG0167	dihydroorotate dehydrogenase activity
BCO26_RS05430	COG0284	orotidine-5'-phosphate decarboxylase activity
BCO26_RS05435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCO26_RS05465	COG1803	Methylglyoxal synthase
BCO26_RS05480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCO26_RS05485	COG0477	Major facilitator Superfamily
BCO26_RS05495	COG0628	permease
BCO26_RS05500	COG3573	Dehydrogenase
BCO26_RS05505	COG2211	Major facilitator Superfamily
BCO26_RS05525	COG2226	methyltransferase
BCO26_RS05535	COG0720	synthase
BCO26_RS05545	COG0385	Bile acid
BCO26_RS05555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCO26_RS05560	COG1561	YicC-like family, N-terminal region
BCO26_RS05565	COG2052	Domain of unknown function (DUF370)
BCO26_RS05570	COG0194	GDP metabolic process
BCO26_RS05575	COG1758	RNA polymerase activity
BCO26_RS05580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCO26_RS05585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCO26_RS05590	COG0242	peptide deformylase activity
BCO26_RS05595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCO26_RS05600	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCO26_RS05600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCO26_RS05605	COG0631	protein serine/threonine phosphatase activity
BCO26_RS05610	COG0515	serine threonine protein kinase
BCO26_RS05610	COG2815	serine threonine protein kinase
BCO26_RS05620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCO26_RS05625	COG1564	THIamine pyrophosphokinase
BCO26_RS05635	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCO26_RS05640	COG1302	Protein conserved in bacteria
BCO26_RS05645	COG1461	Dihydroxyacetone kinase
BCO26_RS05655	COG1760	l-serine dehydratase
BCO26_RS05660	COG1760	l-serine dehydratase
BCO26_RS05665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCO26_RS05670	COG1349	DNA-binding transcription factor activity
BCO26_RS05675	COG0416	fatty acid biosynthetic process
BCO26_RS05680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCO26_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS05695	COG0571	ribonuclease III activity
BCO26_RS05700	COG1196	nuclear chromosome segregation
BCO26_RS05705	COG0552	protein localization to endoplasmic reticulum
BCO26_RS05710	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BCO26_RS05715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCO26_RS05725	COG1837	Belongs to the UPF0109 family
BCO26_RS05735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCO26_RS05740	COG0336	Belongs to the RNA methyltransferase TrmD family
BCO26_RS05755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCO26_RS05770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCO26_RS05775	COG0045	succinate-CoA ligase (ADP-forming) activity
BCO26_RS05780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCO26_RS05785	COG0758	DNA mediated transformation
BCO26_RS05790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCO26_RS05800	COG4974	Belongs to the 'phage' integrase family
BCO26_RS05805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BCO26_RS05815	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BCO26_RS05820	COG1815	bacterial-type flagellum-dependent cell motility
BCO26_RS05825	COG1558	bacterial-type flagellum-dependent cell motility
BCO26_RS05830	COG1677	Flagellar hook-basal body complex protein FliE
BCO26_RS05835	COG1766	The M ring may be actively involved in energy transduction
BCO26_RS05840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCO26_RS05845	COG1317	bacterial-type flagellum organization
BCO26_RS05850	COG1157	protein secretion by the type III secretion system
BCO26_RS05855	COG2882	bacterial-type flagellum organization
BCO26_RS05870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCO26_RS05880	COG4786	Flagellar basal body rod
BCO26_RS05890	COG1580	Controls the rotational direction of flagella during chemotaxis
BCO26_RS05895	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCO26_RS05900	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCO26_RS05900	COG1776	CheC inhibitor of MCP methylation
BCO26_RS05905	COG2201	protein-glutamate methylesterase activity
BCO26_RS05910	COG3190	flagellar
BCO26_RS05915	COG1338	Plays a role in the flagellum-specific transport system
BCO26_RS05920	COG1987	bacterial-type flagellum assembly
BCO26_RS05925	COG1684	flagellar biosynthetic protein fliR
BCO26_RS05930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCO26_RS05935	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCO26_RS05940	COG1419	protein localization to endoplasmic reticulum
BCO26_RS05945	COG0455	bacterial-type flagellum organization
BCO26_RS05950	COG2201	protein-glutamate methylesterase activity
BCO26_RS05955	COG2198	Histidine kinase
BCO26_RS05955	COG0643	Histidine kinase
BCO26_RS05960	COG0835	chemotaxis
BCO26_RS05965	COG1776	CheC inhibitor of MCP methylation
BCO26_RS05970	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BCO26_RS05975	COG1191	sigma factor activity
BCO26_RS05985	COG0052	Belongs to the universal ribosomal protein uS2 family
BCO26_RS05990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCO26_RS05995	COG0528	UMP kinase activity
BCO26_RS06000	COG0233	cytoplasmic translational termination
BCO26_RS06010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCO26_RS06015	COG4589	Belongs to the CDS family
BCO26_RS06020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCO26_RS06025	COG0750	zinc metalloprotease
BCO26_RS06030	COG0442	prolyl-tRNA aminoacylation
BCO26_RS06035	COG2176	DNA-directed DNA polymerase activity
BCO26_RS06045	COG0779	Required for maturation of 30S ribosomal subunits
BCO26_RS06050	COG0195	Participates in both transcription termination and antitermination
BCO26_RS06055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BCO26_RS06060	COG1358	cellular component organization or biogenesis
BCO26_RS06070	COG1550	Protein conserved in bacteria
BCO26_RS06075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCO26_RS06080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCO26_RS06085	COG0196	riboflavin kinase activity
BCO26_RS06090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCO26_RS06095	COG1185	polyribonucleotide nucleotidyltransferase activity
BCO26_RS06100	COG0726	polysaccharide deacetylase
BCO26_RS06105	COG0612	Peptidase, M16
BCO26_RS06110	COG1873	PFAM PRC-barrel domain
BCO26_RS06115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCO26_RS06120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCO26_RS06125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCO26_RS06135	COG0527	aspartate kinase activity
BCO26_RS06145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCO26_RS06150	COG0740	serine-type endopeptidase activity
BCO26_RS06160	COG4980	gas vesicle protein
BCO26_RS06160	COG1674	ftsk spoiiie
BCO26_RS06165	COG1744	ABC transporter substrate-binding protein PnrA-like
BCO26_RS06170	COG3845	ABC transporter
BCO26_RS06175	COG4603	Belongs to the binding-protein-dependent transport system permease family
BCO26_RS06180	COG1079	Belongs to the binding-protein-dependent transport system permease family
BCO26_RS06185	COG0612	Peptidase, M16
BCO26_RS06190	COG0612	Peptidase, M16
BCO26_RS06195	COG0300	oxidoreductase activity
BCO26_RS06210	COG1426	Protein conserved in bacteria
BCO26_RS06215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCO26_RS06220	COG1546	Belongs to the CinA family
BCO26_RS06220	COG1058	Belongs to the CinA family
BCO26_RS06230	COG1418	mRNA catabolic process
BCO26_RS06235	COG1692	metallophosphoesterase
BCO26_RS06240	COG2359	stage V sporulation protein S
BCO26_RS06245	COG0826	peptidase U32
BCO26_RS06250	COG0826	peptidase U32
BCO26_RS06265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCO26_RS06270	COG4550	Control of competence regulator ComK, YlbF/YmcA
BCO26_RS06280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCO26_RS06285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCO26_RS06305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCO26_RS06315	COG0464	growth
BCO26_RS06320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCO26_RS06325	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BCO26_RS06330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCO26_RS06350	COG1321	iron dependent repressor
BCO26_RS06355	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BCO26_RS06365	COG0488	(ABC) transporter
BCO26_RS06370	COG1413	lyase activity
BCO26_RS06385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BCO26_RS06390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCO26_RS06395	COG1272	protein, Hemolysin III
BCO26_RS06400	COG2755	lipolytic protein G-D-S-L family
BCO26_RS06410	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BCO26_RS06410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCO26_RS06415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCO26_RS06420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCO26_RS06430	COG0840	transmembrane signaling receptor activity
BCO26_RS06455	COG1876	peptidase activity
BCO26_RS06460	COG0793	Belongs to the peptidase S41A family
BCO26_RS06460	COG3409	Peptidoglycan-binding domain 1 protein
BCO26_RS06465	COG1846	Transcriptional regulator
BCO26_RS06475	COG2340	Cysteine-rich secretory protein family
BCO26_RS06480	COG0534	Mate efflux family protein
BCO26_RS06490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCO26_RS06495	COG1793	dna ligase
BCO26_RS06495	COG3285	dna ligase
BCO26_RS06500	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BCO26_RS06505	COG0671	phosphoesterase, PA-phosphatase related
BCO26_RS06510	COG1368	sulfuric ester hydrolase activity
BCO26_RS06515	COG1331	Highly conserved protein containing a thioredoxin domain
BCO26_RS06520	COG2814	Major facilitator Superfamily
BCO26_RS06525	COG0745	RESPONSE REGULATOR receiver
BCO26_RS06530	COG5002	protein histidine kinase activity
BCO26_RS06545	COG0567	Dehydrogenase, E1 component
BCO26_RS06550	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCO26_RS06555	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS06575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCO26_RS06585	COG1054	Belongs to the UPF0176 family
BCO26_RS06590	COG2135	peptidase activity
BCO26_RS06600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCO26_RS06605	COG0516	GMP reductase activity
BCO26_RS06605	COG0517	IMP dehydrogenase activity
BCO26_RS06615	COG1388	LysM domain
BCO26_RS06615	COG3584	3D domain protein
BCO26_RS06620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCO26_RS06625	COG1113	amino acid transport
BCO26_RS06630	COG0598	Magnesium transport protein CorA
BCO26_RS06640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BCO26_RS06645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCO26_RS06655	COG0131	Imidazoleglycerol-phosphate dehydratase
BCO26_RS06660	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCO26_RS06670	COG0107	imidazoleglycerol-phosphate synthase activity
BCO26_RS06675	COG0140	phosphoribosyl-ATP diphosphatase activity
BCO26_RS06675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCO26_RS06685	COG2391	methyltransferase activity
BCO26_RS06690	COG2962	Rard protein
BCO26_RS06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCO26_RS06700	COG0569	domain protein
BCO26_RS06720	COG2807	transmembrane transport
BCO26_RS06725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCO26_RS06735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCO26_RS06745	COG1278	Cold shock
BCO26_RS06755	COG0302	gtp cyclohydrolase
BCO26_RS06760	COG3634	alkyl hydroperoxide reductase activity
BCO26_RS06775	COG0577	efflux transmembrane transporter activity
BCO26_RS06780	COG1136	(ABC) transporter
BCO26_RS06785	COG0642	Histidine kinase
BCO26_RS06790	COG0745	RESPONSE REGULATOR receiver
BCO26_RS06800	COG1113	amino acid transport
BCO26_RS06845	COG0477	Major facilitator Superfamily
BCO26_RS06855	COG1132	(ABC) transporter
BCO26_RS06860	COG1132	(ABC) transporter
BCO26_RS06870	COG1380	Effector of murein hydrolase LrgA
BCO26_RS06875	COG1346	cytolysis
BCO26_RS06880	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS06910	COG2309	aminopeptidase activity
BCO26_RS06920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCO26_RS06935	COG0824	Thioesterase
BCO26_RS06945	COG4841	protein insertion into membrane
BCO26_RS06950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCO26_RS06955	COG1832	CoA-binding protein
BCO26_RS06960	COG0187	DNA topoisomerase II activity
BCO26_RS06965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCO26_RS06980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BCO26_RS06985	COG0574	Belongs to the PEP-utilizing enzyme family
BCO26_RS06985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCO26_RS07005	COG2070	2-Nitropropane dioxygenase
BCO26_RS07010	COG0681	Belongs to the peptidase S26 family
BCO26_RS07030	COG0456	acetyltransferase
BCO26_RS07035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCO26_RS07040	COG0456	acetyltransferase
BCO26_RS07050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCO26_RS07055	COG0351	phosphomethylpyrimidine kinase
BCO26_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS07065	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BCO26_RS07070	COG0351	phosphomethylpyrimidine kinase
BCO26_RS07075	COG0352	thiamine-phosphate diphosphorylase activity
BCO26_RS07085	COG2258	MOSC domain
BCO26_RS07145	COG1309	transcriptional regulator
BCO26_RS07150	COG2814	Major facilitator Superfamily
BCO26_RS07155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCO26_RS07160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCO26_RS07180	COG2045	Belongs to the ComB family
BCO26_RS07185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCO26_RS07190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCO26_RS07200	COG0789	Transcriptional regulator
BCO26_RS07210	COG0697	spore germination
BCO26_RS07215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCO26_RS07220	COG0022	dehydrogenase e1 component
BCO26_RS07225	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCO26_RS07230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCO26_RS07235	COG3284	Transcriptional regulator
BCO26_RS07240	COG3264	Mechanosensitive ion channel
BCO26_RS07240	COG1511	domain protein
BCO26_RS07255	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCO26_RS07270	COG0183	Belongs to the thiolase family
BCO26_RS07275	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS07285	COG0561	phosphatase activity
BCO26_RS07290	COG2322	membrane
BCO26_RS07305	COG0039	L-malate dehydrogenase activity
BCO26_RS07310	COG0367	asparagine synthase
BCO26_RS07315	COG2814	Major facilitator Superfamily
BCO26_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS07335	COG2223	nitrite transmembrane transporter activity
BCO26_RS07340	COG3773	Cell wall hydrolase
BCO26_RS07345	COG0708	Exodeoxyribonuclease III
BCO26_RS07355	COG0297	glycogen (starch) synthase activity
BCO26_RS07360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCO26_RS07365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCO26_RS07370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCO26_RS07390	COG1247	-acetyltransferase
BCO26_RS07395	COG0494	nUDIX hydrolase
BCO26_RS07400	COG1914	H( )-stimulated, divalent metal cation uptake system
BCO26_RS07405	COG0783	Belongs to the Dps family
BCO26_RS07415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCO26_RS07420	COG1131	(ABC) transporter
BCO26_RS07445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCO26_RS07455	COG2030	dehydratase
BCO26_RS07475	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BCO26_RS07480	COG0709	Synthesizes selenophosphate from selenide and ATP
BCO26_RS07490	COG0701	Predicted permease
BCO26_RS07495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCO26_RS07500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCO26_RS07510	COG1252	NADH dehydrogenase
BCO26_RS07515	COG2404	hydrolase activity, acting on ester bonds
BCO26_RS07525	COG4990	cell redox homeostasis
BCO26_RS07530	COG0789	Transcriptional regulator
BCO26_RS07555	COG0436	Aminotransferase
BCO26_RS07560	COG0165	Argininosuccinate lyase
BCO26_RS07565	COG0137	argininosuccinate synthase activity
BCO26_RS07570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCO26_RS07575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCO26_RS07580	COG0505	Belongs to the CarA family
BCO26_RS07585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCO26_RS07590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCO26_RS07595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BCO26_RS07600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCO26_RS07635	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCO26_RS07640	COG2027	D-alanyl-D-alanine carboxypeptidase
BCO26_RS07645	COG0204	Acyl-transferase
BCO26_RS07655	COG4846	Membrane protein involved in cytochrome C biogenesis
BCO26_RS07660	COG2201	protein-glutamate methylesterase activity
BCO26_RS07665	COG0785	Cytochrome C biogenesis protein
BCO26_RS07670	COG3763	UPF0154 protein
BCO26_RS07685	COG4224	UPF0291 protein
BCO26_RS07690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCO26_RS07700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCO26_RS07705	COG0174	glutamine synthetase
BCO26_RS07710	COG0789	Transcriptional regulator
BCO26_RS07715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCO26_RS07730	COG2233	PERMEase
BCO26_RS07745	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCO26_RS07750	COG0116	Belongs to the methyltransferase superfamily
BCO26_RS07760	COG4474	Belongs to the UPF0398 family
BCO26_RS07775	COG3359	exonuclease
BCO26_RS07780	COG1205	dead DEAH box helicase
BCO26_RS07780	COG1111	helicase
BCO26_RS07785	COG0071	Belongs to the small heat shock protein (HSP20) family
BCO26_RS07810	COG3331	DNA recombination
BCO26_RS07815	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCO26_RS07815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCO26_RS07820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCO26_RS07825	COG3935	DnaD domain protein
BCO26_RS07830	COG0017	Asparaginyl-tRNA synthetase
BCO26_RS07845	COG1199	ATP-dependent helicase activity
BCO26_RS07845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCO26_RS07850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCO26_RS07855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCO26_RS07875	COG0438	transferase activity, transferring glycosyl groups
BCO26_RS07880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCO26_RS07885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCO26_RS07890	COG1694	Mazg nucleotide pyrophosphohydrolase
BCO26_RS07895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCO26_RS07905	COG2738	Putative neutral zinc metallopeptidase
BCO26_RS07915	COG4347	Protein of unknown function (DUF1405)
BCO26_RS07925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCO26_RS07940	COG5582	Belongs to the UPF0302 family
BCO26_RS07945	COG0457	Tetratricopeptide repeat
BCO26_RS07950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCO26_RS07955	COG0287	Prephenate dehydrogenase
BCO26_RS07960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCO26_RS07965	COG4401	Chorismate mutase type I
BCO26_RS07970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCO26_RS07975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCO26_RS07980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCO26_RS07985	COG0105	UTP biosynthetic process
BCO26_RS07990	COG0142	geranyltranstransferase activity
BCO26_RS07995	COG2226	methyltransferase
BCO26_RS08000	COG0142	geranyltranstransferase activity
BCO26_RS08015	COG0776	regulation of translation
BCO26_RS08020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCO26_RS08040	COG1160	GTP binding
BCO26_RS08050	COG0539	negative regulation of cytoplasmic translation
BCO26_RS08055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCO26_RS08060	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BCO26_RS08065	COG2959	enzyme of heme biosynthesis
BCO26_RS08070	COG3773	Cell wall hydrolase
BCO26_RS08070	COG3409	Peptidoglycan-binding domain 1 protein
BCO26_RS08075	COG2339	peptidase activity
BCO26_RS08085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCO26_RS08095	COG1408	metallophosphoesterase
BCO26_RS08110	COG3546	catalase activity
BCO26_RS08125	COG1266	CAAX protease self-immunity
BCO26_RS08130	COG0514	ATP-dependent DNA helicase (RecQ)
BCO26_RS08140	COG1141	Ferredoxin
BCO26_RS08145	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCO26_RS08150	COG0741	lytic transglycosylase activity
BCO26_RS08150	COG0739	heme binding
BCO26_RS08150	COG1196	nuclear chromosome segregation
BCO26_RS08155	COG5002	protein histidine kinase activity
BCO26_RS08160	COG0745	RESPONSE REGULATOR receiver
BCO26_RS08165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCO26_RS08170	COG1333	cytochrome c biogenesis protein
BCO26_RS08175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCO26_RS08180	COG1187	pseudouridine synthase activity
BCO26_RS08185	COG0700	Nucleoside recognition
BCO26_RS08190	COG2715	membrane protein required for spore maturation
BCO26_RS08195	COG1686	Belongs to the peptidase S11 family
BCO26_RS08200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCO26_RS08220	COG0697	spore germination
BCO26_RS08240	COG1191	sigma factor activity
BCO26_RS08255	COG1686	Belongs to the peptidase S11 family
BCO26_RS08260	COG4974	Belongs to the 'phage' integrase family
BCO26_RS08270	COG0735	belongs to the Fur family
BCO26_RS08275	COG1300	Membrane
BCO26_RS08280	COG1379	DNA repair
BCO26_RS08295	COG0667	Aldo Keto reductase
BCO26_RS08305	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BCO26_RS08310	COG3853	Toxic anion resistance protein (TelA)
BCO26_RS08315	COG1073	alpha beta
BCO26_RS08320	COG3858	chitin binding
BCO26_RS08320	COG1388	LysM domain
BCO26_RS08330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCO26_RS08335	COG0300	oxidoreductase activity
BCO26_RS08340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCO26_RS08350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCO26_RS08365	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCO26_RS08370	COG1376	ErfK ybiS ycfS ynhG family protein
BCO26_RS08380	COG1105	Belongs to the carbohydrate kinase PfkB family
BCO26_RS08385	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCO26_RS08390	COG0022	dehydrogenase e1 component
BCO26_RS08395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCO26_RS08400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCO26_RS08405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCO26_RS08410	COG3290	protein histidine kinase activity
BCO26_RS08410	COG3829	transcription factor binding
BCO26_RS08425	COG0584	glycerophosphoryl diester phosphodiesterase
BCO26_RS08430	COG0745	RESPONSE REGULATOR receiver
BCO26_RS08435	COG0750	zinc metalloprotease
BCO26_RS08440	COG0497	DNA recombination
BCO26_RS08450	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BCO26_RS08455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCO26_RS08470	COG1570	exodeoxyribonuclease VII activity
BCO26_RS08475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCO26_RS08485	COG1302	Protein conserved in bacteria
BCO26_RS08490	COG0439	Biotin carboxylase
BCO26_RS08495	COG0511	ligase activity, forming carbon-carbon bonds
BCO26_RS08535	COG3854	ATPases associated with a variety of cellular activities
BCO26_RS08540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCO26_RS08545	COG0006	proline dipeptidase activity
BCO26_RS08550	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCO26_RS08560	COG3872	metal-dependent enzyme
BCO26_RS08570	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCO26_RS08575	COG0183	Belongs to the thiolase family
BCO26_RS08580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCO26_RS08585	COG0095	Lipoate-protein ligase
BCO26_RS08590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCO26_RS08595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCO26_RS08605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCO26_RS08610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCO26_RS08620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCO26_RS08645	COG4537	Required for transformation and DNA binding
BCO26_RS08650	COG1459	type II secretion system
BCO26_RS08655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCO26_RS08670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCO26_RS08680	COG1940	carbohydrate kinase activity
BCO26_RS08685	COG4483	Protein conserved in bacteria
BCO26_RS08695	COG0705	Rhomboid family
BCO26_RS08695	COG0457	Tetratricopeptide repeat
BCO26_RS08700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCO26_RS08710	COG0768	penicillin binding
BCO26_RS08715	COG0477	Major facilitator Superfamily
BCO26_RS08720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCO26_RS08730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCO26_RS08735	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BCO26_RS08740	COG0735	belongs to the Fur family
BCO26_RS08745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCO26_RS08750	COG1121	(ABC) transporter
BCO26_RS08760	COG0791	NLP P60 protein
BCO26_RS08760	COG3883	PFAM NLP P60 protein
BCO26_RS08765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BCO26_RS08770	COG0513	Belongs to the DEAD box helicase family
BCO26_RS08785	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCO26_RS08790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCO26_RS08795	COG2384	SAM-dependent methyltransferase
BCO26_RS08800	COG2010	Cytochrome c
BCO26_RS08810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCO26_RS08815	COG0358	DNA primase activity
BCO26_RS08825	COG0517	IMP dehydrogenase activity
BCO26_RS08830	COG1381	Involved in DNA repair and RecF pathway recombination
BCO26_RS08835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCO26_RS08840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCO26_RS08845	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCO26_RS08850	COG1480	7TM receptor with intracellular HD hydrolase
BCO26_RS08855	COG1702	phosphate starvation-inducible protein PhoH
BCO26_RS08875	COG1610	YqeY-like protein
BCO26_RS08890	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCO26_RS08895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCO26_RS08900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCO26_RS08905	COG2264	protein methyltransferase activity
BCO26_RS08915	COG0443	Heat shock 70 kDa protein
BCO26_RS08920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCO26_RS08930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCO26_RS08935	COG0481	GTPase activity
BCO26_RS08940	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCO26_RS08945	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCO26_RS08950	COG0268	Binds directly to 16S ribosomal RNA
BCO26_RS08955	COG1466	dna polymerase III delta subunit
BCO26_RS08965	COG0658	competence protein
BCO26_RS08965	COG2333	competence protein COMEC
BCO26_RS08970	COG2131	deaminase
BCO26_RS08975	COG1596	polysaccharide export
BCO26_RS08975	COG1555	photosystem II stabilization
BCO26_RS08980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCO26_RS08985	COG2226	methyltransferase
BCO26_RS08990	COG0799	negative regulation of ribosome biogenesis
BCO26_RS08995	COG1713	HD superfamily hydrolase involved in NAD metabolism
BCO26_RS09000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCO26_RS09005	COG1534	Rna-binding protein
BCO26_RS09015	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCO26_RS09020	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BCO26_RS09025	COG0247	lactate metabolic process
BCO26_RS09030	COG0277	FAD linked oxidase domain protein
BCO26_RS09035	COG3835	regulator
BCO26_RS09040	COG2132	Multicopper oxidase
BCO26_RS09045	COG0071	Belongs to the small heat shock protein (HSP20) family
BCO26_RS09050	COG2210	Belongs to the sulfur carrier protein TusA family
BCO26_RS09065	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCO26_RS09085	COG0071	Belongs to the small heat shock protein (HSP20) family
BCO26_RS09095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCO26_RS09105	COG1704	LemA family
BCO26_RS09145	COG3634	alkyl hydroperoxide reductase activity
BCO26_RS09150	COG0450	alkyl hydroperoxide reductase
BCO26_RS09180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCO26_RS09185	COG0572	uridine kinase
BCO26_RS09190	COG4122	O-methyltransferase activity
BCO26_RS09195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCO26_RS09200	COG3906	Belongs to the UPF0473 family
BCO26_RS09205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCO26_RS09210	COG4472	Bacterial protein of unknown function (DUF965)
BCO26_RS09215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCO26_RS09220	COG0628	permease
BCO26_RS09240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCO26_RS09245	COG0457	Tetratricopeptide repeat
BCO26_RS09245	COG1477	protein flavinylation
BCO26_RS09250	COG0482	sulfurtransferase activity
BCO26_RS09255	COG1104	cysteine desulfurase activity
BCO26_RS09260	COG1959	2 iron, 2 sulfur cluster binding
BCO26_RS09265	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS09270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCO26_RS09275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCO26_RS09280	COG0385	Bile acid
BCO26_RS09285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCO26_RS09290	COG0124	histidyl-tRNA synthetase
BCO26_RS09295	COG4991	sh3 domain protein
BCO26_RS09295	COG3103	Sh3 type 3 domain protein
BCO26_RS09295	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCO26_RS09300	COG2814	Major facilitator Superfamily
BCO26_RS09305	COG1566	PFAM secretion protein HlyD family protein
BCO26_RS09310	COG1846	Transcriptional regulator
BCO26_RS09315	COG1490	D-aminoacyl-tRNA deacylase activity
BCO26_RS09320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCO26_RS09325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCO26_RS09330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCO26_RS09330	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCO26_RS09335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCO26_RS09335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCO26_RS09345	COG2244	polysaccharide biosynthetic process
BCO26_RS09350	COG2323	membrane
BCO26_RS09360	COG1862	Preprotein translocase
BCO26_RS09365	COG0343	queuine tRNA-ribosyltransferase activity
BCO26_RS09370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCO26_RS09385	COG0632	four-way junction helicase activity
BCO26_RS09395	COG0217	transcriptional regulatory protein
BCO26_RS09405	COG1388	LysM domain
BCO26_RS09410	COG1827	regulation of RNA biosynthetic process
BCO26_RS09415	COG0077	Prephenate dehydratase
BCO26_RS09420	COG4492	Belongs to the UPF0735 family
BCO26_RS09425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCO26_RS09430	COG3290	protein histidine kinase activity
BCO26_RS09435	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCO26_RS09440	COG2868	ribosomal protein
BCO26_RS09445	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCO26_RS09450	COG1530	ribonuclease E activity
BCO26_RS09455	COG1994	Peptidase M50
BCO26_RS09465	COG2894	cell division
BCO26_RS09470	COG0850	regulation of cytokinetic process
BCO26_RS09480	COG1792	Involved in formation and maintenance of cell shape
BCO26_RS09485	COG1077	Cell shape determining protein MreB Mrl
BCO26_RS09490	COG2003	Belongs to the UPF0758 family
BCO26_RS09510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCO26_RS09535	COG1459	type II secretion system
BCO26_RS09545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCO26_RS09580	COG0285	dihydrofolate synthase activity
BCO26_RS09585	COG0525	valine-tRNA ligase activity
BCO26_RS09595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCO26_RS09600	COG1388	LysM domain
BCO26_RS09610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCO26_RS09615	COG0113	porphobilinogen synthase activity
BCO26_RS09625	COG0181	hydroxymethylbilane synthase activity
BCO26_RS09630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCO26_RS09650	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCO26_RS09655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BCO26_RS09660	COG0470	DNA polymerase III
BCO26_RS09660	COG1067	ATP-dependent peptidase activity
BCO26_RS09670	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCO26_RS09675	COG0457	Tetratricopeptide repeat
BCO26_RS09675	COG1477	protein flavinylation
BCO26_RS09695	COG0622	Phosphoesterase
BCO26_RS09700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BCO26_RS09705	COG5401	PFAM Sporulation and spore germination
BCO26_RS09715	COG5577	PFAM Coat F domain
BCO26_RS09720	COG1063	alcohol dehydrogenase
BCO26_RS09725	COG5577	PFAM Coat F domain
BCO26_RS09740	COG1846	Transcriptional regulator
BCO26_RS09775	COG2197	response regulator
BCO26_RS09785	COG0824	Thioesterase
BCO26_RS09790	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCO26_RS09795	COG1053	succinate dehydrogenase
BCO26_RS09800	COG2009	succinate dehydrogenase
BCO26_RS09805	COG1719	4-vinyl reductase, 4VR
BCO26_RS09815	COG0322	excinuclease ABC activity
BCO26_RS09820	COG3118	belongs to the thioredoxin family
BCO26_RS09825	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCO26_RS09830	COG2086	electron transfer activity
BCO26_RS09835	COG1024	Enoyl-CoA hydratase
BCO26_RS09840	COG1309	transcriptional regulator
BCO26_RS09845	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS09850	COG1193	negative regulation of DNA recombination
BCO26_RS09855	COG1796	DNA polymerase
BCO26_RS09855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCO26_RS09860	COG1286	toxin biosynthetic process
BCO26_RS09865	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BCO26_RS09880	COG0072	phenylalanine-tRNA ligase activity
BCO26_RS09880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCO26_RS09885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCO26_RS09890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCO26_RS09915	COG1695	Transcriptional regulator
BCO26_RS09935	COG0431	NADPH-dependent FMN reductase
BCO26_RS09940	COG1363	Peptidase, m42
BCO26_RS09950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCO26_RS09960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCO26_RS09970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCO26_RS09980	COG1484	DNA-dependent DNA replication
BCO26_RS09985	COG3611	Membrane attachment protein
BCO26_RS09990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BCO26_RS10000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCO26_RS10005	COG0237	dephospho-CoA kinase activity
BCO26_RS10010	COG1971	Probably functions as a manganese efflux pump
BCO26_RS10015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCO26_RS10020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCO26_RS10020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCO26_RS10025	COG0039	L-malate dehydrogenase activity
BCO26_RS10030	COG0538	isocitrate dehydrogenase activity
BCO26_RS10035	COG0372	Belongs to the citrate synthase family
BCO26_RS10040	COG2707	UPF0756 membrane protein
BCO26_RS10045	COG0628	permease
BCO26_RS10055	COG0205	6-phosphofructokinase activity
BCO26_RS10060	COG0825	malonyl-CoA metabolic process
BCO26_RS10065	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCO26_RS10070	COG0281	malic enzyme
BCO26_RS10075	COG0587	DNA-directed DNA polymerase activity
BCO26_RS10090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCO26_RS10100	COG4109	DRTGG domain
BCO26_RS10105	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCO26_RS10110	COG0006	proline dipeptidase activity
BCO26_RS10120	COG0589	response to stress
BCO26_RS10130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCO26_RS10135	COG0827	DNA restriction-modification system
BCO26_RS10140	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCO26_RS10145	COG3874	Sporulation protein YtfJ
BCO26_RS10155	COG1714	RDD family
BCO26_RS10160	COG0616	signal peptide processing
BCO26_RS10165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCO26_RS10175	COG0301	tRNA thio-modification
BCO26_RS10180	COG1104	cysteine desulfurase activity
BCO26_RS10190	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BCO26_RS10195	COG1309	transcriptional regulator
BCO26_RS10200	COG1956	GAF domain-containing protein
BCO26_RS10205	COG2203	Gaf domain
BCO26_RS10205	COG2199	diguanylate cyclase activity
BCO26_RS10210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCO26_RS10225	COG0506	proline dehydrogenase activity
BCO26_RS10230	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS10235	COG3829	transcription factor binding
BCO26_RS10235	COG3290	protein histidine kinase activity
BCO26_RS10250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCO26_RS10255	COG3383	formate dehydrogenase (NAD+) activity
BCO26_RS10260	COG2427	Protein of unknown function (DUF1641)
BCO26_RS10265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCO26_RS10270	COG0315	cyclic pyranopterin monophosphate synthase activity
BCO26_RS10275	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCO26_RS10280	COG0314	molybdopterin synthase activity
BCO26_RS10285	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCO26_RS10290	COG0303	'Molybdopterin
BCO26_RS10305	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCO26_RS10310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCO26_RS10315	COG4149	molybdate abc transporter
BCO26_RS10325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCO26_RS10330	COG0454	-acetyltransferase
BCO26_RS10335	COG0517	IMP dehydrogenase activity
BCO26_RS10340	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCO26_RS10350	COG1605	Chorismate mutase
BCO26_RS10350	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCO26_RS10355	COG4980	gas vesicle protein
BCO26_RS10365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCO26_RS10370	COG1674	ftsk spoiiie
BCO26_RS10380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCO26_RS10385	COG4848	Belongs to the UPF0354 family
BCO26_RS10390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCO26_RS10395	COG2208	phosphoserine phosphatase activity
BCO26_RS10410	COG5584	Small secreted protein
BCO26_RS10415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCO26_RS10425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCO26_RS10435	COG0510	thiamine kinase activity
BCO26_RS10460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCO26_RS10470	COG1349	DNA-binding transcription factor activity
BCO26_RS10475	COG2244	polysaccharide biosynthetic process
BCO26_RS10495	COG0495	leucyl-tRNA aminoacylation
BCO26_RS10500	COG2814	Major facilitator Superfamily
BCO26_RS10515	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BCO26_RS10525	COG2267	carboxylic ester hydrolase activity
BCO26_RS10530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCO26_RS10535	COG0367	asparagine synthase
BCO26_RS10540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCO26_RS10560	COG1506	peptidase
BCO26_RS10565	COG0655	NAD(P)H dehydrogenase (quinone) activity
BCO26_RS10575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCO26_RS10580	COG1116	anion transmembrane transporter activity
BCO26_RS10585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCO26_RS10600	COG0783	Belongs to the Dps family
BCO26_RS10605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCO26_RS10610	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCO26_RS10615	COG4948	Mandelate Racemase Muconate Lactonizing
BCO26_RS10620	COG0318	PFAM AMP-dependent synthetase and ligase
BCO26_RS10625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCO26_RS10630	COG0596	Alpha beta hydrolase
BCO26_RS10635	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BCO26_RS10640	COG1169	isochorismate synthase
BCO26_RS10645	COG1575	Belongs to the MenA family. Type 1 subfamily
BCO26_RS10790	COG1285	pathogenesis
BCO26_RS10805	COG2217	Heavy metal translocating P-type atpase
BCO26_RS10810	COG2608	mercury ion transmembrane transporter activity
BCO26_RS10820	COG1522	sequence-specific DNA binding
BCO26_RS10840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCO26_RS10865	COG5002	protein histidine kinase activity
BCO26_RS10870	COG0745	RESPONSE REGULATOR receiver
BCO26_RS10875	COG1388	LysM domain
BCO26_RS10880	COG4221	oxidoreductase activity
BCO26_RS10890	COG0726	polysaccharide deacetylase
BCO26_RS10905	COG0038	chloride channel
BCO26_RS10910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCO26_RS10915	COG1937	Protein conserved in bacteria
BCO26_RS10925	COG1525	nuclease
BCO26_RS10930	COG2190	(PTS) system
BCO26_RS10935	COG2160	L-arabinose isomerase activity
BCO26_RS10940	COG0235	Class ii aldolase
BCO26_RS10955	COG1609	Transcriptional regulator
BCO26_RS10960	COG0840	transmembrane signaling receptor activity
BCO26_RS10975	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS10985	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BCO26_RS11000	COG1012	belongs to the aldehyde dehydrogenase family
BCO26_RS11025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCO26_RS11035	COG2155	Conserved Protein
BCO26_RS11045	COG1098	S1 RNA binding domain
BCO26_RS11055	COG1902	pentaerythritol trinitrate reductase activity
BCO26_RS11060	COG0656	L-ascorbic acid biosynthetic process
BCO26_RS11080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCO26_RS11090	COG2814	Major facilitator Superfamily
BCO26_RS11095	COG2050	protein possibly involved in aromatic compounds catabolism
BCO26_RS11110	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCO26_RS11120	COG0697	spore germination
BCO26_RS11130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCO26_RS11135	COG3584	3D domain protein
BCO26_RS11145	COG1252	NADH dehydrogenase
BCO26_RS11150	COG0492	ferredoxin-NADP+ reductase activity
BCO26_RS11155	COG0316	Belongs to the HesB IscA family
BCO26_RS11160	COG4837	Protein of unknown function (DUF1462)
BCO26_RS11165	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCO26_RS11170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCO26_RS11175	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCO26_RS11180	COG0647	UMP catabolic process
BCO26_RS11185	COG2445	Protein of unknown function DUF86
BCO26_RS11190	COG4470	Protein conserved in bacteria
BCO26_RS11195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCO26_RS11200	COG0739	heme binding
BCO26_RS11210	COG3377	Domain of unknown function (DUF1805)
BCO26_RS11215	COG0737	Belongs to the 5'-nucleotidase family
BCO26_RS11220	COG0719	Fe-S assembly protein
BCO26_RS11225	COG0822	iron-sulfur transferase activity
BCO26_RS11230	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCO26_RS11235	COG0719	Fe-S assembly protein
BCO26_RS11240	COG0396	ATPase activity
BCO26_RS11255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCO26_RS11260	COG0509	glycine decarboxylation via glycine cleavage system
BCO26_RS11265	COG1393	Belongs to the ArsC family
BCO26_RS11270	COG1960	acyl-CoA dehydrogenase activity
BCO26_RS11280	COG0183	Belongs to the thiolase family
BCO26_RS11285	COG1024	Enoyl-CoA hydratase
BCO26_RS11285	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCO26_RS11295	COG5577	PFAM Coat F domain
BCO26_RS11300	COG0772	Belongs to the SEDS family
BCO26_RS11305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCO26_RS11315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCO26_RS11335	COG2200	EAL domain
BCO26_RS11335	COG2199	diguanylate cyclase activity
BCO26_RS11335	COG2202	Pas domain
BCO26_RS11340	COG0753	catalase activity
BCO26_RS11345	COG0671	phosphoesterase, PA-phosphatase related
BCO26_RS11355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCO26_RS11375	COG1595	DNA-templated transcription, initiation
BCO26_RS11385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCO26_RS11410	COG3335	DDE superfamily endonuclease
BCO26_RS11425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCO26_RS11430	COG0557	exoribonuclease II activity
BCO26_RS11440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCO26_RS11445	COG0148	phosphopyruvate hydratase activity
BCO26_RS11450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BCO26_RS11460	COG0126	phosphoglycerate kinase activity
BCO26_RS11480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCO26_RS11495	COG3383	formate dehydrogenase (NAD+) activity
BCO26_RS11510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCO26_RS11520	COG4608	Belongs to the ABC transporter superfamily
BCO26_RS11525	COG0791	NLP P60 protein
BCO26_RS11530	COG4166	transmembrane transport
BCO26_RS11535	COG0444	Belongs to the ABC transporter superfamily
BCO26_RS11540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCO26_RS11545	COG0601	transmembrane transport
BCO26_RS11550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BCO26_RS11560	COG0598	Magnesium transport protein CorA
BCO26_RS11575	COG2719	SpoVR family
BCO26_RS11580	COG3594	Acyltransferase
BCO26_RS11610	COG1392	Phosphate transport regulator
BCO26_RS11615	COG0306	phosphate transporter
BCO26_RS11630	COG2718	Belongs to the UPF0229 family
BCO26_RS11640	COG2766	serine protein kinase
BCO26_RS11650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCO26_RS11665	COG2095	MarC family integral membrane protein
BCO26_RS11680	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BCO26_RS11685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCO26_RS11690	COG0765	amino acid transport
BCO26_RS11695	COG1126	abc transporter atp-binding protein
BCO26_RS11700	COG2116	formate transmembrane transporter activity
BCO26_RS11710	COG1882	Formate acetyltransferase
BCO26_RS11715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCO26_RS11725	COG0431	NADPH-dependent FMN reductase
BCO26_RS11740	COG1131	(ABC) transporter
BCO26_RS11755	COG3586	endonuclease activity
BCO26_RS11775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCO26_RS11885	COG3527	Alpha-acetolactate decarboxylase
BCO26_RS11890	COG0028	Belongs to the TPP enzyme family
BCO26_RS11895	COG0583	DNA-binding transcription factor activity
BCO26_RS11900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCO26_RS11905	COG0735	belongs to the Fur family
BCO26_RS11925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCO26_RS11945	COG4129	membrane
BCO26_RS11950	COG1737	Transcriptional regulator
BCO26_RS11955	COG1263	PTS System
BCO26_RS11955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCO26_RS11960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCO26_RS11970	COG1132	(ABC) transporter
BCO26_RS11975	COG3557	Belongs to the UPF0374 family
BCO26_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS11995	COG0583	DNA-binding transcription factor activity
BCO26_RS12000	COG0067	glutamate synthase
BCO26_RS12000	COG0069	glutamate synthase activity
BCO26_RS12000	COG0070	glutamate synthase
BCO26_RS12005	COG0493	'glutamate synthase
BCO26_RS12035	COG1988	membrane-bound metal-dependent
BCO26_RS12040	COG1194	a g-specific adenine glycosylase
BCO26_RS12065	COG0159	tryptophan synthase activity
BCO26_RS12075	COG0134	indole-3-glycerol-phosphate synthase activity
BCO26_RS12080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCO26_RS12085	COG0512	Glutamine amidotransferase of anthranilate synthase
BCO26_RS12085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCO26_RS12095	COG1136	(ABC) transporter
BCO26_RS12095	COG0577	efflux transmembrane transporter activity
BCO26_RS12115	COG0840	transmembrane signaling receptor activity
BCO26_RS12120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCO26_RS12125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCO26_RS12130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCO26_RS12145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCO26_RS12150	COG0066	3-isopropylmalate dehydratase activity
BCO26_RS12155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCO26_RS12165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCO26_RS12170	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCO26_RS12175	COG0440	acetolactate synthase activity
BCO26_RS12180	COG0028	Belongs to the TPP enzyme family
BCO26_RS12185	COG0129	dihydroxy-acid dehydratase activity
BCO26_RS12195	COG1114	Component of the transport system for branched-chain amino acids
BCO26_RS12200	COG1366	Belongs to the anti-sigma-factor antagonist family
BCO26_RS12220	COG2124	cytochrome p450
BCO26_RS12225	COG0670	Belongs to the BI1 family
BCO26_RS12230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCO26_RS12235	COG2223	nitrite transmembrane transporter activity
BCO26_RS12250	COG3279	Response regulator of the LytR AlgR family
BCO26_RS12255	COG3275	phosphorelay sensor kinase activity
BCO26_RS12260	COG0252	asparaginase activity
BCO26_RS12265	COG2132	Multicopper oxidase
BCO26_RS12270	COG1309	transcriptional regulator
BCO26_RS12275	COG1511	domain protein
BCO26_RS12305	COG1823	symporter activity
BCO26_RS12310	COG2839	Protein conserved in bacteria
BCO26_RS12330	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BCO26_RS12335	COG0477	Major facilitator Superfamily
BCO26_RS12345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCO26_RS12350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCO26_RS12360	COG0840	transmembrane signaling receptor activity
BCO26_RS12365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCO26_RS12385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCO26_RS12395	COG1132	(ABC) transporter
BCO26_RS12400	COG1846	Transcriptional regulator
BCO26_RS12425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCO26_RS12450	COG0387	Pfam Sodium calcium exchanger
BCO26_RS12455	COG0477	Major facilitator Superfamily
BCO26_RS12460	COG1295	ribonuclease BN
BCO26_RS12465	COG4840	Belongs to the UPF0435 family
BCO26_RS12470	COG0024	Methionine aminopeptidase
BCO26_RS12475	COG0693	protein deglycase activity
BCO26_RS12480	COG1360	Flagellar Motor Protein
BCO26_RS12485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCO26_RS12495	COG3189	MarR family transcriptional regulator
BCO26_RS12505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCO26_RS12510	COG1607	acyl-coa hydrolase
BCO26_RS12515	COG1077	Cell shape determining protein MreB Mrl
BCO26_RS12520	COG2268	Band 7 protein
BCO26_RS12525	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCO26_RS12530	COG0626	cystathionine gamma-synthase activity
BCO26_RS12535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCO26_RS12540	COG1854	S-ribosylhomocysteine lyase activity
BCO26_RS12545	COG2226	methyltransferase
BCO26_RS12550	COG0288	reversible hydration of carbon dioxide
BCO26_RS12555	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCO26_RS12565	COG2197	response regulator
BCO26_RS12585	COG4086	secreted protein
BCO26_RS12590	COG1737	Transcriptional regulator
BCO26_RS12595	COG0737	Belongs to the 5'-nucleotidase family
BCO26_RS12615	COG3620	sequence-specific DNA binding
BCO26_RS12640	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BCO26_RS12645	COG1518	maintenance of DNA repeat elements
BCO26_RS12695	COG1304	FMN binding
BCO26_RS12700	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BCO26_RS12705	COG0166	Belongs to the GPI family
BCO26_RS12710	COG0025	NhaP-type Na H and K H
BCO26_RS12715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCO26_RS12715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCO26_RS12715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCO26_RS12720	COG1349	DNA-binding transcription factor activity
BCO26_RS12730	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BCO26_RS12745	COG0561	phosphatase activity
BCO26_RS12760	COG2814	Major facilitator Superfamily
BCO26_RS12765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCO26_RS12785	COG2357	RelA SpoT domain protein
BCO26_RS12790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCO26_RS12795	COG0667	Aldo Keto reductase
BCO26_RS12800	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BCO26_RS12805	COG1461	Dihydroxyacetone kinase
BCO26_RS12810	COG2376	Dihydroxyacetone kinase
BCO26_RS12870	COG0778	Nitroreductase
BCO26_RS12905	COG0006	proline dipeptidase activity
BCO26_RS12915	COG1113	amino acid transport
BCO26_RS12920	COG0730	response to heat
BCO26_RS12935	COG2233	PERMEase
BCO26_RS12940	COG0210	DNA helicase
BCO26_RS12945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCO26_RS12965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCO26_RS12980	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BCO26_RS13025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCO26_RS13030	COG2223	nitrite transmembrane transporter activity
BCO26_RS13035	COG3588	fructose-bisphosphate aldolase
BCO26_RS13055	COG0753	catalase activity
BCO26_RS13070	COG5444	nuclease activity
BCO26_RS13100	COG0494	nUDIX hydrolase
BCO26_RS13105	COG1715	Restriction endonuclease
BCO26_RS13110	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCO26_RS13135	COG1280	lysine exporter protein (LysE YggA)
BCO26_RS13140	COG0386	Belongs to the glutathione peroxidase family
BCO26_RS13145	COG2190	(PTS) system
BCO26_RS13165	COG3403	YqcI/YcgG family
BCO26_RS13170	COG0582	viral genome integration into host DNA
BCO26_RS13195	COG1328	CTP reductase activity
BCO26_RS13205	COG1063	alcohol dehydrogenase
BCO26_RS13210	COG1929	Belongs to the glycerate kinase type-1 family
BCO26_RS13220	COG1879	ABC-type sugar transport system periplasmic component
BCO26_RS13225	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCO26_RS13230	COG1129	ABC transporter
BCO26_RS13235	COG1869	D-ribose catabolic process
BCO26_RS13240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCO26_RS13245	COG1609	Transcriptional regulator
BCO26_RS13270	COG1132	(ABC) transporter
BCO26_RS13275	COG1132	(ABC) transporter
BCO26_RS13285	COG0791	NLP P60 protein
BCO26_RS13285	COG1388	LysM domain
BCO26_RS13315	COG3153	acetyltransferase
BCO26_RS13315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCO26_RS13320	COG5583	Uncharacterized small protein (DUF2292)
BCO26_RS13325	COG0431	NADPH-dependent FMN reductase
BCO26_RS13335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCO26_RS13340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCO26_RS13345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCO26_RS13350	COG0516	GMP reductase activity
BCO26_RS13365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCO26_RS13375	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCO26_RS13380	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCO26_RS13390	COG2390	Transcriptional regulator
BCO26_RS13400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCO26_RS13415	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BCO26_RS13430	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BCO26_RS13435	COG1984	allophanate hydrolase subunit 2
BCO26_RS13440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCO26_RS13445	COG2814	Major facilitator Superfamily
BCO26_RS13450	COG1764	response to oxidative stress
BCO26_RS13455	COG1126	abc transporter atp-binding protein
BCO26_RS13460	COG0765	amino acid transport
BCO26_RS13465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCO26_RS13470	COG1473	amidohydrolase
BCO26_RS13475	COG0326	Molecular chaperone. Has ATPase activity
BCO26_RS13500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCO26_RS13515	COG1064	alcohol dehydrogenase
BCO26_RS13585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCO26_RS13590	COG1597	lipid kinase activity
BCO26_RS13615	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCO26_RS13620	COG0154	amidase activity
BCO26_RS13625	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCO26_RS13630	COG2224	Isocitrate lyase
BCO26_RS13635	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCO26_RS13640	COG4851	CamS sex pheromone cAM373 precursor
BCO26_RS13650	COG0210	DNA helicase
BCO26_RS13655	COG0210	DNA helicase
BCO26_RS13660	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BCO26_RS13665	COG4496	protein, YerC YecD
BCO26_RS13670	COG1470	cell adhesion involved in biofilm formation
BCO26_RS13685	COG0151	Belongs to the GarS family
BCO26_RS13695	COG0138	bifunctional purine biosynthesis protein purh
BCO26_RS13700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCO26_RS13705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCO26_RS13710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCO26_RS13715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCO26_RS13720	COG0047	phosphoribosylformylglycinamidine synthase activity
BCO26_RS13725	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCO26_RS13735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCO26_RS13740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCO26_RS13745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCO26_RS13755	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BCO26_RS13760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCO26_RS13785	COG1301	dicarboxylic acid transport
BCO26_RS13795	COG3711	transcriptional antiterminator
BCO26_RS13800	COG2252	PERMEase
BCO26_RS13815	COG2814	Major facilitator Superfamily
BCO26_RS13830	COG0471	metal ion transport
BCO26_RS13855	COG1131	(ABC) transporter
BCO26_RS13865	COG1725	Transcriptional regulator
BCO26_RS13875	COG2910	NAD(P)H-binding
BCO26_RS13880	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCO26_RS13885	COG0425	Belongs to the sulfur carrier protein TusA family
BCO26_RS13890	COG2391	methyltransferase activity
BCO26_RS13900	COG1028	Short-chain dehydrogenase reductase Sdr
BCO26_RS13930	COG1120	ATPase activity
BCO26_RS13960	COG3620	sequence-specific DNA binding
BCO26_RS13975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCO26_RS13975	COG0519	Catalyzes the synthesis of GMP from XMP
BCO26_RS13985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCO26_RS13990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCO26_RS13995	COG1335	isochorismatase
BCO26_RS14000	COG4948	Mandelate Racemase Muconate Lactonizing
BCO26_RS14010	COG0463	Glycosyl transferase, family 2
BCO26_RS14015	COG2246	polysaccharide biosynthetic process
BCO26_RS14020	COG0459	protein refolding
BCO26_RS14025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCO26_RS14030	COG1266	CAAX protease self-immunity
BCO26_RS14040	COG0805	protein transport
BCO26_RS14045	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BCO26_RS14050	COG0488	(ABC) transporter
BCO26_RS14060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCO26_RS14065	COG0456	acetyltransferase
BCO26_RS14070	COG1214	PFAM Peptidase M22, glycoprotease
BCO26_RS14075	COG0802	atpase or kinase
BCO26_RS14140	COG3091	SprT-like family
BCO26_RS14145	COG2183	response to ionizing radiation
BCO26_RS14150	COG2208	phosphoserine phosphatase activity
BCO26_RS14155	COG1191	sigma factor activity
BCO26_RS14160	COG2172	sigma factor antagonist activity
BCO26_RS14165	COG1366	Belongs to the anti-sigma-factor antagonist family
BCO26_RS14170	COG2208	phosphoserine phosphatase activity
BCO26_RS14175	COG2172	sigma factor antagonist activity
BCO26_RS14180	COG1366	Belongs to the anti-sigma-factor antagonist family
BCO26_RS14185	COG1366	Belongs to the anti-sigma-factor antagonist family
BCO26_RS14195	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCO26_RS14200	COG0864	Transcriptional regulator
BCO26_RS14205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCO26_RS14210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCO26_RS14215	COG0736	holo-[acyl-carrier-protein] synthase activity
BCO26_RS14220	COG0705	Rhomboid family
BCO26_RS14225	COG0513	Belongs to the DEAD box helicase family
BCO26_RS14235	COG1280	lysine exporter protein (LysE YggA)
BCO26_RS14240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCO26_RS14245	COG1609	Transcriptional regulator
BCO26_RS14250	COG0366	Alpha amylase catalytic
BCO26_RS14260	COG2182	Extracellular solute-binding protein
BCO26_RS14265	COG1175	transmembrane transport
BCO26_RS14270	COG3833	ABC-type maltose transport systems, permease component
BCO26_RS14275	COG5521	maltodextrose utilization protein MalA
BCO26_RS14280	COG1554	hydrolase, family 65, central catalytic
BCO26_RS14290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCO26_RS14295	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCO26_RS14305	COG1253	flavin adenine dinucleotide binding
BCO26_RS14310	COG0789	Transcriptional regulator
BCO26_RS14315	COG1253	flavin adenine dinucleotide binding
BCO26_RS14325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCO26_RS14340	COG0629	single-stranded DNA binding
BCO26_RS14345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCO26_RS14350	COG4786	Flagellar basal body rod
BCO26_RS14355	COG4786	Flagellar basal body rod
BCO26_RS14360	COG1077	Cell shape determining protein MreB Mrl
BCO26_RS14370	COG1609	Transcriptional regulator
BCO26_RS14375	COG0739	heme binding
BCO26_RS14380	COG2385	sporulation resulting in formation of a cellular spore
BCO26_RS14385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCO26_RS14395	COG4836	Membrane
BCO26_RS14400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCO26_RS14405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCO26_RS14410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCO26_RS14415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCO26_RS14420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCO26_RS14430	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCO26_RS14435	COG0356	it plays a direct role in the translocation of protons across the membrane
BCO26_RS14445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCO26_RS14450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCO26_RS14455	COG4475	Protein of unknown function (DUF436)
BCO26_RS14460	COG0698	ribose 5-phosphate isomerase
BCO26_RS14465	COG0840	transmembrane signaling receptor activity
BCO26_RS14475	COG1971	Probably functions as a manganese efflux pump
BCO26_RS14480	COG0009	L-threonylcarbamoyladenylate synthase
BCO26_RS14500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCO26_RS14510	COG1435	thymidine kinase activity
BCO26_RS14515	COG0254	rRNA binding
BCO26_RS14520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCO26_RS14525	COG1494	fructose-1,6-bisphosphatase
BCO26_RS14530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCO26_RS14535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCO26_RS14545	COG0191	fructose-bisphosphate aldolase activity
BCO26_RS14550	COG2204	response regulator
BCO26_RS14565	COG1131	(ABC) transporter
BCO26_RS14570	COG1725	Transcriptional regulator
BCO26_RS14575	COG0504	CTP synthase activity
BCO26_RS14580	COG3343	RNA polymerase activity
BCO26_RS14595	COG1703	isobutyryl-CoA mutase activity
BCO26_RS14595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCO26_RS14595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCO26_RS14600	COG1309	transcriptional regulator
BCO26_RS14605	COG1960	acyl-CoA dehydrogenase activity
BCO26_RS14610	COG1960	acyl-CoA dehydrogenase activity
BCO26_RS14615	COG0183	Belongs to the thiolase family
BCO26_RS14620	COG0247	lactate metabolic process
BCO26_RS14620	COG2181	nitrate reductase activity
BCO26_RS14625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCO26_RS14630	COG0018	arginyl-trna synthetase
BCO26_RS14640	COG0010	Belongs to the arginase family
BCO26_RS14645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCO26_RS14655	COG1994	Peptidase M50
BCO26_RS14665	COG3465	dGTPase activity
BCO26_RS14670	COG1078	dGTPase activity
BCO26_RS14685	COG0095	Lipoate-protein ligase
BCO26_RS14695	COG0280	phosphate acetyltransferase
BCO26_RS14710	COG3253	May function as heme-dependent peroxidase
BCO26_RS14730	COG2363	Small membrane protein
BCO26_RS14745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCO26_RS14775	COG4555	ABC transporter
BCO26_RS14795	COG0351	phosphomethylpyrimidine kinase
BCO26_RS14805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCO26_RS14810	COG0561	phosphatase activity
BCO26_RS14815	COG0514	ATP-dependent DNA helicase (RecQ)
BCO26_RS14820	COG1785	Belongs to the alkaline phosphatase family
BCO26_RS14825	COG1737	Transcriptional regulator
BCO26_RS14835	COG5002	protein histidine kinase activity
BCO26_RS14835	COG3850	Histidine kinase
BCO26_RS14840	COG0745	RESPONSE REGULATOR receiver
BCO26_RS14850	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCO26_RS14855	COG1346	cytolysis
BCO26_RS14860	COG1380	Effector of murein hydrolase LrgA
BCO26_RS14865	COG0583	DNA-binding transcription factor activity
BCO26_RS14870	COG0367	asparagine synthase
BCO26_RS14895	COG2966	Psort location CytoplasmicMembrane, score
BCO26_RS14900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCO26_RS14905	COG1966	Carbon starvation protein
BCO26_RS14910	COG1464	Belongs to the NlpA lipoprotein family
BCO26_RS14915	COG2011	ABC-type metal ion transport system permease component
BCO26_RS14920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCO26_RS14925	COG1119	ATPase activity
BCO26_RS14940	COG0534	Mate efflux family protein
BCO26_RS14950	COG1442	glycosyl transferase family 8
BCO26_RS14955	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCO26_RS14960	COG2814	Major facilitator Superfamily
BCO26_RS14975	COG0028	Belongs to the TPP enzyme family
BCO26_RS14980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCO26_RS14990	COG3842	ATPase activity
BCO26_RS15010	COG0584	glycerophosphoryl diester phosphodiesterase
BCO26_RS15035	COG1132	(ABC) transporter
BCO26_RS15045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCO26_RS15065	COG1366	Belongs to the anti-sigma-factor antagonist family
BCO26_RS15095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCO26_RS15100	COG1126	abc transporter atp-binding protein
BCO26_RS15110	COG0765	amino acid transport
BCO26_RS15115	COG0579	oxidoreductase
BCO26_RS15120	COG0477	Major facilitator Superfamily
BCO26_RS15140	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCO26_RS15150	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCO26_RS15170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCO26_RS15175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCO26_RS15180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCO26_RS15185	COG4853	Protein conserved in bacteria
BCO26_RS15195	COG5002	protein histidine kinase activity
BCO26_RS15200	COG0745	RESPONSE REGULATOR receiver
BCO26_RS15215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCO26_RS15220	COG0305	Participates in initiation and elongation during chromosome replication
BCO26_RS15225	COG0359	binds to the 23S rRNA
BCO26_RS15230	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BCO26_RS15240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCO26_RS15250	COG0360	Binds together with S18 to 16S ribosomal RNA
BCO26_RS15255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCO26_RS15260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCO26_RS15260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCO26_RS15265	COG0307	riboflavin synthase, alpha
BCO26_RS15270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCO26_RS15270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCO26_RS15275	COG0012	GTP binding
BCO26_RS15280	COG4481	Protein conserved in bacteria
BCO26_RS15285	COG0668	transmembrane transport
BCO26_RS15295	COG1811	Na channel or pump
BCO26_RS15300	COG1475	DNA binding
BCO26_RS15305	COG1192	Involved in chromosome partitioning
BCO26_RS15310	COG1475	DNA binding
BCO26_RS15315	COG0357	Ribosomal RNA small subunit methyltransferase G
BCO26_RS15320	COG0445	tRNA wobble uridine modification
BCO26_RS15325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCO26_RS15330	COG1847	R3H domain protein
BCO26_RS15335	COG0706	membrane insertase activity
BCO26_RS15340	COG0594	ribonuclease P activity
BCO26_RS15345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCO26_RS15370	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCO26_RS15380	COG0732	type I restriction modification DNA specificity domain