locus-tag	class	description
BCOA_RS17190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCOA_RS17195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCOA_RS17200	COG1873	PFAM PRC-barrel domain
BCOA_RS17205	COG0612	Peptidase, M16
BCOA_RS17210	COG0726	polysaccharide deacetylase
BCOA_RS17215	COG1185	polyribonucleotide nucleotidyltransferase activity
BCOA_RS17220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCOA_RS17225	COG0196	riboflavin kinase activity
BCOA_RS17230	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCOA_RS17235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCOA_RS17240	COG1550	Protein conserved in bacteria
BCOA_RS17250	COG1358	cellular component organization or biogenesis
BCOA_RS17255	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BCOA_RS17260	COG0195	Participates in both transcription termination and antitermination
BCOA_RS17265	COG0779	Required for maturation of 30S ribosomal subunits
BCOA_RS17270	COG2176	DNA-directed DNA polymerase activity
BCOA_RS17275	COG0442	prolyl-tRNA aminoacylation
BCOA_RS17280	COG0750	zinc metalloprotease
BCOA_RS17290	COG4589	Belongs to the CDS family
BCOA_RS17295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCOA_RS17305	COG0233	cytoplasmic translational termination
BCOA_RS17310	COG0528	UMP kinase activity
BCOA_RS17315	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCOA_RS17320	COG0052	Belongs to the universal ribosomal protein uS2 family
BCOA_RS17330	COG1191	sigma factor activity
BCOA_RS17335	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BCOA_RS17340	COG1776	CheC inhibitor of MCP methylation
BCOA_RS17345	COG0835	chemotaxis
BCOA_RS17350	COG0643	Histidine kinase
BCOA_RS17350	COG2198	Histidine kinase
BCOA_RS17355	COG2201	protein-glutamate methylesterase activity
BCOA_RS17360	COG0455	bacterial-type flagellum organization
BCOA_RS17365	COG1419	protein localization to endoplasmic reticulum
BCOA_RS17370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCOA_RS17375	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCOA_RS17380	COG1684	flagellar biosynthetic protein fliR
BCOA_RS17385	COG1987	bacterial-type flagellum assembly
BCOA_RS17390	COG1338	Plays a role in the flagellum-specific transport system
BCOA_RS17395	COG3190	flagellar
BCOA_RS17400	COG2201	protein-glutamate methylesterase activity
BCOA_RS17405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCOA_RS17405	COG1776	CheC inhibitor of MCP methylation
BCOA_RS17410	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCOA_RS17415	COG1580	Controls the rotational direction of flagella during chemotaxis
BCOA_RS17425	COG4786	Flagellar basal body rod
BCOA_RS17435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BCOA_RS17450	COG2882	bacterial-type flagellum organization
BCOA_RS17455	COG1157	protein secretion by the type III secretion system
BCOA_RS17460	COG1317	bacterial-type flagellum organization
BCOA_RS17465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCOA_RS17470	COG1766	The M ring may be actively involved in energy transduction
BCOA_RS17475	COG1677	Flagellar hook-basal body complex protein FliE
BCOA_RS17480	COG1558	bacterial-type flagellum-dependent cell motility
BCOA_RS17485	COG1815	bacterial-type flagellum-dependent cell motility
BCOA_RS17490	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BCOA_RS17500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BCOA_RS17505	COG4974	Belongs to the 'phage' integrase family
BCOA_RS17520	COG0758	DNA mediated transformation
BCOA_RS17525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCOA_RS17530	COG0045	succinate-CoA ligase (ADP-forming) activity
BCOA_RS17535	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCOA_RS17550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCOA_RS17565	COG0336	Belongs to the RNA methyltransferase TrmD family
BCOA_RS17570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCOA_RS17580	COG1837	Belongs to the UPF0109 family
BCOA_RS17590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCOA_RS17595	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BCOA_RS17600	COG0552	protein localization to endoplasmic reticulum
BCOA_RS17610	COG1196	nuclear chromosome segregation
BCOA_RS17615	COG0571	ribonuclease III activity
BCOA_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS17630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCOA_RS17635	COG0416	fatty acid biosynthetic process
BCOA_RS17640	COG1349	DNA-binding transcription factor activity
BCOA_RS17645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCOA_RS17650	COG1760	l-serine dehydratase
BCOA_RS17655	COG1760	l-serine dehydratase
BCOA_RS17665	COG1461	Dihydroxyacetone kinase
BCOA_RS17670	COG1302	Protein conserved in bacteria
BCOA_RS17675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCOA_RS17685	COG1564	THIamine pyrophosphokinase
BCOA_RS17690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCOA_RS17700	COG0515	serine threonine protein kinase
BCOA_RS17700	COG2815	serine threonine protein kinase
BCOA_RS17705	COG0631	protein serine/threonine phosphatase activity
BCOA_RS17710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCOA_RS17710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCOA_RS17715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCOA_RS17720	COG0242	peptide deformylase activity
BCOA_RS17725	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCOA_RS17730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCOA_RS17735	COG1758	RNA polymerase activity
BCOA_RS17740	COG0194	GDP metabolic process
BCOA_RS17745	COG2052	Domain of unknown function (DUF370)
BCOA_RS17750	COG1561	YicC-like family, N-terminal region
BCOA_RS17755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCOA_RS17770	COG0385	Bile acid
BCOA_RS17780	COG0720	synthase
BCOA_RS17800	COG0561	phosphatase activity
BCOA_RS17805	COG0628	permease
BCOA_RS17815	COG1309	transcriptional regulator
BCOA_RS17820	COG0477	Major facilitator Superfamily
BCOA_RS17825	COG0477	Major facilitator Superfamily
BCOA_RS17830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCOA_RS17835	COG1803	Methylglyoxal synthase
BCOA_RS17840	COG1454	alcohol dehydrogenase
BCOA_RS17845	COG0235	Class ii aldolase
BCOA_RS17850	COG4806	L-rhamnose isomerase
BCOA_RS17855	COG1070	Carbohydrate kinase
BCOA_RS17860	COG2207	Transcriptional regulator
BCOA_RS17860	COG1917	Cupin 2, conserved barrel domain protein
BCOA_RS17880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCOA_RS17885	COG0284	orotidine-5'-phosphate decarboxylase activity
BCOA_RS17890	COG0167	dihydroorotate dehydrogenase activity
BCOA_RS17910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCOA_RS17915	COG0540	Belongs to the ATCase OTCase family
BCOA_RS17920	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BCOA_RS17925	COG0564	pseudouridine synthase activity
BCOA_RS17930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCOA_RS17945	COG3599	regulation of cell shape
BCOA_RS17950	COG2302	S4 RNA-binding domain
BCOA_RS17955	COG0762	integral membrane protein
BCOA_RS17960	COG1799	cell septum assembly
BCOA_RS17965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCOA_RS17975	COG3584	3D domain protein
BCOA_RS17975	COG1388	LysM domain
BCOA_RS17980	COG1873	PFAM PRC-barrel domain
BCOA_RS17985	COG1191	sigma factor activity
BCOA_RS17990	COG1191	sigma factor activity
BCOA_RS18005	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCOA_RS18010	COG0849	cell division
BCOA_RS18015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCOA_RS18020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCOA_RS18025	COG0772	Belongs to the SEDS family
BCOA_RS18030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCOA_RS18035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCOA_RS18050	COG0768	penicillin binding
BCOA_RS18055	COG0768	penicillin binding
BCOA_RS18060	COG4839	cell division protein FtsL
BCOA_RS18065	COG0275	rRNA processing
BCOA_RS18070	COG2001	Belongs to the MraZ family
BCOA_RS18075	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BCOA_RS18080	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCOA_RS18085	COG0454	-acetyltransferase
BCOA_RS18095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCOA_RS18100	COG1399	metal-binding, possibly nucleic acid-binding protein
BCOA_RS18105	COG1323	Belongs to the UPF0348 family
BCOA_RS18110	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCOA_RS18115	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCOA_RS18120	COG3314	Sporulation integral membrane protein YlbJ
BCOA_RS18125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCOA_RS18130	COG0742	ribosomal rna small subunit methyltransferase
BCOA_RS18140	COG4471	UPF0298 protein
BCOA_RS18145	COG3679	Belongs to the UPF0342 family
BCOA_RS18165	COG2050	protein possibly involved in aromatic compounds catabolism
BCOA_RS18170	COG2340	Cysteine-rich secretory protein family
BCOA_RS18180	COG3336	cytochrome c oxidase
BCOA_RS18185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCOA_RS18205	COG0109	protoheme IX farnesyltransferase activity
BCOA_RS18210	COG1612	heme a metabolic process
BCOA_RS18215	COG0772	Belongs to the SEDS family
BCOA_RS18220	COG4838	Belongs to the UPF0358 family
BCOA_RS18225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCOA_RS18230	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCOA_RS18240	COG1217	gtp-binding protein TYPA
BCOA_RS18250	COG0483	inositol monophosphate 1-phosphatase activity
BCOA_RS18265	COG4476	Belongs to the UPF0223 family
BCOA_RS18270	COG1982	Orn Lys Arg decarboxylase major
BCOA_RS18310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCOA_RS18320	COG1473	amidohydrolase
BCOA_RS18325	COG2171	N-acyltransferase activity
BCOA_RS18330	COG0583	DNA-binding transcription factor activity
BCOA_RS18335	COG0517	IMP dehydrogenase activity
BCOA_RS18340	COG4703	Protein of unknown function (DUF1797)
BCOA_RS18350	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS18370	COG2409	Drug exporters of the RND superfamily
BCOA_RS18370	COG1033	growth of symbiont in host cell
BCOA_RS18380	COG0784	Response regulator, receiver
BCOA_RS18380	COG0835	chemotaxis
BCOA_RS18385	COG0436	Aminotransferase
BCOA_RS18390	COG2084	Dehydrogenase
BCOA_RS18410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS18425	COG4873	Protein conserved in bacteria
BCOA_RS18435	COG3949	Membrane
BCOA_RS18440	COG0542	response to heat
BCOA_RS18455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCOA_RS18460	COG5002	protein histidine kinase activity
BCOA_RS18475	COG0861	Integral membrane protein TerC family
BCOA_RS18485	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BCOA_RS18490	COG3852	Histidine kinase
BCOA_RS18495	COG0673	inositol 2-dehydrogenase activity
BCOA_RS18500	COG0783	Belongs to the Dps family
BCOA_RS18505	COG0730	response to heat
BCOA_RS18515	COG1959	2 iron, 2 sulfur cluster binding
BCOA_RS18535	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS18580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCOA_RS18600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCOA_RS18605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCOA_RS18635	COG1522	sequence-specific DNA binding
BCOA_RS18640	COG2059	Chromate
BCOA_RS18645	COG2059	Chromate
BCOA_RS18650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCOA_RS18680	COG3579	cysteine-type endopeptidase activity
BCOA_RS18690	COG1668	transmembrane transport
BCOA_RS18695	COG4152	abc transporter atp-binding protein
BCOA_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS18710	COG1940	carbohydrate kinase activity
BCOA_RS18740	COG2382	esterase
BCOA_RS18750	COG2153	protein acetylation
BCOA_RS18780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCOA_RS18820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BCOA_RS18825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCOA_RS18830	COG0564	pseudouridine synthase activity
BCOA_RS18840	COG2357	RelA SpoT domain protein
BCOA_RS18855	COG0741	lytic transglycosylase activity
BCOA_RS18870	COG2346	COG2346, Truncated hemoglobins
BCOA_RS18875	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCOA_RS18890	COG1164	Oligoendopeptidase f
BCOA_RS18895	COG4469	Competence protein
BCOA_RS18900	COG4862	establishment of competence for transformation
BCOA_RS18910	COG1393	Belongs to the ArsC family
BCOA_RS18915	COG4608	Belongs to the ABC transporter superfamily
BCOA_RS18920	COG0444	Belongs to the ABC transporter superfamily
BCOA_RS18925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCOA_RS18930	COG0601	transmembrane transport
BCOA_RS18935	COG4166	transmembrane transport
BCOA_RS18945	COG0180	Tryptophanyl-tRNA synthetase
BCOA_RS18955	COG0747	negative chemotaxis
BCOA_RS18965	COG0601	transmembrane transport
BCOA_RS18970	COG4608	Belongs to the ABC transporter superfamily
BCOA_RS18985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCOA_RS18990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCOA_RS19025	COG2151	metal-sulfur cluster biosynthetic enzyme
BCOA_RS19030	COG0561	phosphatase activity
BCOA_RS19045	COG1307	EDD domain protein, DegV family
BCOA_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS19065	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCOA_RS19070	COG2311	Membrane
BCOA_RS19105	COG1074	ATP-dependent DNA helicase activity
BCOA_RS19110	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BCOA_RS19135	COG0501	Belongs to the peptidase M48B family
BCOA_RS19145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BCOA_RS19155	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS19160	COG0095	Lipoate-protein ligase
BCOA_RS19170	COG1999	signal sequence binding
BCOA_RS19175	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS19180	COG0697	spore germination
BCOA_RS19185	COG2814	Major facilitator Superfamily
BCOA_RS19190	COG3254	rhamnose metabolic process
BCOA_RS19200	COG1349	DNA-binding transcription factor activity
BCOA_RS19205	COG2190	(PTS) system
BCOA_RS19205	COG1263	PTS System
BCOA_RS19205	COG1263	PTS System
BCOA_RS19205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS19205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS19205	COG2190	(PTS) system
BCOA_RS19210	COG1511	domain protein
BCOA_RS19215	COG1309	transcriptional regulator
BCOA_RS19220	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCOA_RS19225	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCOA_RS19230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCOA_RS19235	COG2329	Antibiotic biosynthesis monooxygenase
BCOA_RS19240	COG3069	C4-dicarboxylate transmembrane transporter activity
BCOA_RS19255	COG4473	ABC transporter
BCOA_RS19260	COG1131	(ABC) transporter
BCOA_RS19265	COG0537	adenosine 5'-monophosphoramidase activity
BCOA_RS19285	COG1846	Transcriptional regulator
BCOA_RS19300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BCOA_RS19310	COG3481	metal-dependent phosphohydrolase, HD sub domain
BCOA_RS19315	COG4717	serine-type aminopeptidase activity
BCOA_RS19320	COG0420	3'-5' exonuclease activity
BCOA_RS19325	COG3689	TIGRFAM TIGR03943 family protein
BCOA_RS19330	COG0701	Predicted permease
BCOA_RS19335	COG0861	Integral membrane protein TerC family
BCOA_RS19345	COG1024	Enoyl-CoA hydratase
BCOA_RS19350	COG0561	phosphatase activity
BCOA_RS19360	COG4399	Belongs to the UPF0754 family
BCOA_RS19375	COG0189	ligase activity
BCOA_RS19380	COG0189	ligase activity
BCOA_RS19390	COG2508	Transcriptional regulator
BCOA_RS19395	COG3842	ATPase activity
BCOA_RS19430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS19435	COG1481	regulation of sporulation
BCOA_RS19440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCOA_RS19445	COG1660	Displays ATPase and GTPase activities
BCOA_RS19450	COG1051	belongs to the nudix hydrolase family
BCOA_RS19460	COG0492	ferredoxin-NADP+ reductase activity
BCOA_RS19465	COG0457	Tetratricopeptide repeat
BCOA_RS19470	COG0110	maltose O-acetyltransferase activity
BCOA_RS19475	COG0546	phosphoglycolate phosphatase activity
BCOA_RS19480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCOA_RS19485	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BCOA_RS19495	COG3595	metallopeptidase activity
BCOA_RS19500	COG0463	Glycosyl transferase, family 2
BCOA_RS19500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCOA_RS19505	COG1682	transport, permease protein
BCOA_RS19510	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCOA_RS19520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BCOA_RS19525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCOA_RS19530	COG0556	nucleotide-excision repair
BCOA_RS19575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCOA_RS19590	COG0581	inorganic phosphate transmembrane transporter activity
BCOA_RS19595	COG0573	inorganic phosphate transmembrane transporter activity
BCOA_RS19605	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCOA_RS19610	COG5002	protein histidine kinase activity
BCOA_RS19615	COG0745	RESPONSE REGULATOR receiver
BCOA_RS19630	COG4607	ABC-type enterochelin transport system periplasmic component
BCOA_RS19635	COG4604	ABC transporter, ATP-binding protein
BCOA_RS19640	COG4605	iron ion homeostasis
BCOA_RS19645	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCOA_RS19650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCOA_RS19655	COG3409	Peptidoglycan-binding domain 1 protein
BCOA_RS19655	COG0793	Belongs to the peptidase S41A family
BCOA_RS19660	COG0460	homoserine dehydrogenase
BCOA_RS19675	COG0739	heme binding
BCOA_RS19680	COG2177	Part of the ABC transporter FtsEX involved in
BCOA_RS19685	COG2884	Cell division ATP-binding protein ftsE
BCOA_RS19690	COG2010	Cytochrome c
BCOA_RS19695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCOA_RS19700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCOA_RS19705	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCOA_RS19710	COG0653	protein targeting
BCOA_RS19720	COG0405	Gamma-glutamyltransferase
BCOA_RS19735	COG1516	flagellar protein fliS
BCOA_RS19740	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BCOA_RS19745	COG1334	flagellar protein FlaG
BCOA_RS19755	COG2094	Belongs to the DNA glycosylase MPG family
BCOA_RS19770	COG1067	ATP-dependent peptidase activity
BCOA_RS19780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BCOA_RS19790	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCOA_RS19795	COG4786	Flagellar basal body rod
BCOA_RS19795	COG1256	bacterial-type flagellum assembly
BCOA_RS19805	COG2747	anti-sigma28 factor FlgM
BCOA_RS19815	COG1040	competence protein
BCOA_RS19820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BCOA_RS19825	COG1307	EDD domain protein, DegV family
BCOA_RS19830	COG0531	amino acid
BCOA_RS19835	COG2197	response regulator
BCOA_RS19845	COG1739	Uncharacterized protein family UPF0029
BCOA_RS19855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCOA_RS19865	COG0768	penicillin binding
BCOA_RS19875	COG1388	LysM domain
BCOA_RS19875	COG0791	NLP P60 protein
BCOA_RS19880	COG2188	Transcriptional regulator
BCOA_RS19890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCOA_RS19895	COG0477	Major facilitator Superfamily
BCOA_RS19905	COG1482	cell wall glycoprotein biosynthetic process
BCOA_RS19915	COG0346	lactoylglutathione lyase activity
BCOA_RS19920	COG2996	Protein conserved in bacteria
BCOA_RS19935	COG1609	Transcriptional regulator
BCOA_RS19950	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BCOA_RS19955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCOA_RS19975	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS19980	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS19995	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BCOA_RS20000	COG2409	Drug exporters of the RND superfamily
BCOA_RS20000	COG1033	growth of symbiont in host cell
BCOA_RS20020	COG2814	Major facilitator Superfamily
BCOA_RS20025	COG1113	amino acid transport
BCOA_RS20030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCOA_RS20065	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCOA_RS20080	COG2226	methyltransferase
BCOA_RS20095	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BCOA_RS20100	COG3421	Type III restriction
BCOA_RS20105	COG3344	reverse transcriptase
BCOA_RS20110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCOA_RS20115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCOA_RS20130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCOA_RS20135	COG0436	Aminotransferase
BCOA_RS20140	COG0789	Transcriptional regulator
BCOA_RS20150	COG1664	Polymer-forming cytoskeletal
BCOA_RS20160	COG0534	Mate efflux family protein
BCOA_RS20165	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCOA_RS20170	COG4717	serine-type aminopeptidase activity
BCOA_RS20175	COG0420	3'-5' exonuclease activity
BCOA_RS20180	COG0431	NADPH-dependent FMN reductase
BCOA_RS20185	COG0656	L-ascorbic acid biosynthetic process
BCOA_RS20200	COG0656	L-ascorbic acid biosynthetic process
BCOA_RS20220	COG0561	phosphatase activity
BCOA_RS20230	COG1609	Transcriptional regulator
BCOA_RS20245	COG1063	alcohol dehydrogenase
BCOA_RS20260	COG0535	radical SAM domain protein
BCOA_RS20275	COG0589	response to stress
BCOA_RS20280	COG2244	polysaccharide biosynthetic process
BCOA_RS20285	COG2746	aminoglycoside 3-N-acetyltransferase activity
BCOA_RS20290	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS20295	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS20300	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS20310	COG1268	BioY protein
BCOA_RS20315	COG0024	Methionine aminopeptidase
BCOA_RS20320	COG1388	LysM domain
BCOA_RS20320	COG0791	NLP P60 protein
BCOA_RS20340	COG1454	alcohol dehydrogenase
BCOA_RS20340	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS20360	COG4145	pantothenate transmembrane transporter activity
BCOA_RS20370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCOA_RS20375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BCOA_RS20390	COG0010	Belongs to the arginase family
BCOA_RS20395	COG0460	homoserine dehydrogenase
BCOA_RS20400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCOA_RS20405	COG0083	homoserine kinase activity
BCOA_RS20410	COG1116	anion transmembrane transporter activity
BCOA_RS20415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCOA_RS20420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCOA_RS20430	COG0154	amidase activity
BCOA_RS20440	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCOA_RS20445	COG2079	MmgE PrpD family protein
BCOA_RS20460	COG3716	PTS system mannose fructose sorbose family IID component
BCOA_RS20465	COG3715	PTS system
BCOA_RS20475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS20475	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS20480	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCOA_RS20480	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCOA_RS20490	COG2706	6-phosphogluconolactonase activity
BCOA_RS20495	COG0011	TIGRFAM Protein of
BCOA_RS20505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCOA_RS20515	COG3584	3D domain protein
BCOA_RS20515	COG1388	LysM domain
BCOA_RS20525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BCOA_RS20535	COG5002	protein histidine kinase activity
BCOA_RS20540	COG0745	RESPONSE REGULATOR receiver
BCOA_RS20550	COG1136	(ABC) transporter
BCOA_RS20560	COG1316	TRANSCRIPTIONal
BCOA_RS20565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCOA_RS20575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCOA_RS20585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCOA_RS20590	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS20610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCOA_RS20615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCOA_RS20620	COG0604	alcohol dehydrogenase
BCOA_RS20635	COG2207	Transcriptional regulator
BCOA_RS20640	COG1653	transport
BCOA_RS20660	COG0626	cystathionine gamma-synthase activity
BCOA_RS20665	COG0626	cystathionine gamma-synthase activity
BCOA_RS20675	COG1131	(ABC) transporter
BCOA_RS20685	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BCOA_RS20690	COG3711	transcriptional antiterminator
BCOA_RS20690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS20695	COG2723	6-phospho-beta-galactosidase activity
BCOA_RS20700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCOA_RS20700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCOA_RS20715	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCOA_RS20755	COG0473	3-isopropylmalate dehydrogenase activity
BCOA_RS20790	COG2186	Transcriptional regulator
BCOA_RS20795	COG1620	l-lactate permease
BCOA_RS20805	COG0531	amino acid
BCOA_RS20825	COG2972	Histidine kinase
BCOA_RS20870	COG1363	Peptidase, m42
BCOA_RS20885	COG1309	transcriptional regulator
BCOA_RS20895	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS20900	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS20910	COG1501	Belongs to the glycosyl hydrolase 31 family
BCOA_RS20915	COG3829	transcription factor binding
BCOA_RS20915	COG3290	protein histidine kinase activity
BCOA_RS20925	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS20935	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS20945	COG4720	Psort location CytoplasmicMembrane, score
BCOA_RS20965	COG2116	formate transmembrane transporter activity
BCOA_RS20975	COG1104	cysteine desulfurase activity
BCOA_RS20980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCOA_RS20985	COG0157	Belongs to the NadC ModD family
BCOA_RS21000	COG2115	Belongs to the xylose isomerase family
BCOA_RS21005	COG1070	Carbohydrate kinase
BCOA_RS21010	COG2814	Major facilitator Superfamily
BCOA_RS21015	COG0371	Dehydrogenase
BCOA_RS21025	COG0606	chelatase, subunit chli
BCOA_RS21030	COG2272	Belongs to the type-B carboxylesterase lipase family
BCOA_RS21035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCOA_RS21045	COG4297	protein containing double-stranded beta helix domain
BCOA_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS21065	COG0110	maltose O-acetyltransferase activity
BCOA_RS21070	COG1510	regulation of RNA biosynthetic process
BCOA_RS21075	COG0517	IMP dehydrogenase activity
BCOA_RS21075	COG1125	glycine betaine transport
BCOA_RS21080	COG1174	glycine betaine transport
BCOA_RS21085	COG1732	Glycine betaine
BCOA_RS21105	COG1609	Transcriptional regulator
BCOA_RS21110	COG2814	Major facilitator Superfamily
BCOA_RS21120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCOA_RS21140	COG1113	amino acid transport
BCOA_RS21145	COG2190	(PTS) system
BCOA_RS21145	COG2211	Major facilitator Superfamily
BCOA_RS21150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCOA_RS21160	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCOA_RS21165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BCOA_RS21170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS21170	COG3711	transcriptional antiterminator
BCOA_RS21185	COG2130	NADP-dependent
BCOA_RS21190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BCOA_RS21220	COG4989	oxidoreductase activity
BCOA_RS21230	COG1316	TRANSCRIPTIONal
BCOA_RS21240	COG0531	amino acid
BCOA_RS21255	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BCOA_RS21265	COG2333	competence protein COMEC
BCOA_RS21265	COG0658	competence protein
BCOA_RS21275	COG2315	Protein conserved in bacteria
BCOA_RS21285	COG0145	ligase activity
BCOA_RS21295	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCOA_RS21315	COG1131	(ABC) transporter
BCOA_RS21345	COG3716	PTS system mannose fructose sorbose family IID component
BCOA_RS21350	COG3715	PTS system
BCOA_RS21355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS21355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS21385	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCOA_RS21385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCOA_RS21390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCOA_RS21395	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BCOA_RS21405	COG1396	sequence-specific DNA binding
BCOA_RS21410	COG2188	Transcriptional regulator
BCOA_RS21415	COG0363	glucosamine-6-phosphate deaminase activity
BCOA_RS21420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS21425	COG3715	PTS system
BCOA_RS21430	COG3716	PTS system mannose fructose sorbose family IID component
BCOA_RS21445	COG2226	methyltransferase
BCOA_RS21450	COG5504	Zn-dependent protease
BCOA_RS21480	COG1063	alcohol dehydrogenase
BCOA_RS21490	COG1070	Carbohydrate kinase
BCOA_RS21495	COG2115	Belongs to the xylose isomerase family
BCOA_RS21520	COG0531	amino acid
BCOA_RS21530	COG3665	Urea carboxylase-associated protein
BCOA_RS21535	COG0439	Biotin carboxylase
BCOA_RS21545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BCOA_RS21560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCOA_RS21600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCOA_RS21605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCOA_RS21610	COG4464	protein tyrosine phosphatase activity
BCOA_RS21615	COG0489	protein tyrosine kinase activity
BCOA_RS21620	COG3944	biosynthesis protein
BCOA_RS21645	COG1410	methionine synthase
BCOA_RS21645	COG0646	methionine synthase
BCOA_RS21650	COG0646	methionine synthase
BCOA_RS21650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCOA_RS21665	COG0586	Pfam SNARE associated Golgi protein
BCOA_RS21670	COG0586	Pfam SNARE associated Golgi protein
BCOA_RS21685	COG1733	regulation of RNA biosynthetic process
BCOA_RS21700	COG0765	amino acid transport
BCOA_RS21705	COG0765	amino acid transport
BCOA_RS21710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCOA_RS21725	COG0628	permease
BCOA_RS21730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCOA_RS21745	COG0531	amino acid
BCOA_RS21760	COG0423	glycine-tRNA ligase activity
BCOA_RS21785	COG1902	pentaerythritol trinitrate reductase activity
BCOA_RS21815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCOA_RS21820	COG1301	dicarboxylic acid transport
BCOA_RS21825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCOA_RS21830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCOA_RS21835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCOA_RS21840	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCOA_RS21870	COG3973	AAA domain
BCOA_RS21875	COG0463	Glycosyl transferase, family 2
BCOA_RS21880	COG2851	Citrate transporter
BCOA_RS21885	COG4565	transcriptional regulatory protein
BCOA_RS21890	COG3290	protein histidine kinase activity
BCOA_RS21895	COG0004	ammonium transporteR
BCOA_RS21900	COG1979	alcohol dehydrogenase
BCOA_RS21905	COG0531	amino acid
BCOA_RS21930	COG1953	Uracil, thiamine, allantoin
BCOA_RS21940	COG1454	alcohol dehydrogenase
BCOA_RS21945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCOA_RS21955	COG0247	lactate metabolic process
BCOA_RS21960	COG1139	Iron-sulfur cluster binding protein
BCOA_RS21965	COG1556	Lactate utilization protein
BCOA_RS21970	COG0531	amino acid
BCOA_RS22000	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCOA_RS22005	COG3842	ATPase activity
BCOA_RS22015	COG0833	amino acid
BCOA_RS22020	COG3104	oligopeptide transport
BCOA_RS22030	COG1113	amino acid transport
BCOA_RS22040	COG0667	Aldo Keto reductase
BCOA_RS22045	COG5577	PFAM Coat F domain
BCOA_RS22050	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCOA_RS22065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCOA_RS22075	COG1609	Transcriptional regulator
BCOA_RS22080	COG2848	UPF0210 protein
BCOA_RS22095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCOA_RS22105	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCOA_RS22105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCOA_RS22110	COG0702	epimerase
BCOA_RS22125	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BCOA_RS22130	COG1442	glycosyl transferase family 8
BCOA_RS22130	COG1216	Glycosyl transferase, family 2
BCOA_RS22135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCOA_RS22155	COG0697	spore germination
BCOA_RS22170	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS22175	COG0371	Dehydrogenase
BCOA_RS22180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCOA_RS22205	COG0175	sulfate reduction
BCOA_RS22215	COG5434	Belongs to the glycosyl hydrolase 28 family
BCOA_RS22230	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS22245	COG3226	Transcriptional regulator
BCOA_RS22270	COG1309	transcriptional regulator
BCOA_RS22275	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS22280	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS22290	COG1366	Belongs to the anti-sigma-factor antagonist family
BCOA_RS22295	COG0217	transcriptional regulatory protein
BCOA_RS22325	COG1120	ATPase activity
BCOA_RS22335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCOA_RS22340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCOA_RS22345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCOA_RS22355	COG2076	Multidrug Resistance protein
BCOA_RS22360	COG2076	Multidrug Resistance protein
BCOA_RS22390	COG0463	Glycosyl transferase, family 2
BCOA_RS22395	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCOA_RS22400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCOA_RS22410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCOA_RS22415	COG2217	Heavy metal translocating P-type atpase
BCOA_RS22425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCOA_RS22435	COG0716	FMN binding
BCOA_RS22445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCOA_RS22455	COG1070	Carbohydrate kinase
BCOA_RS22465	COG2188	Transcriptional regulator
BCOA_RS22470	COG0366	Alpha amylase catalytic
BCOA_RS22475	COG1263	PTS System
BCOA_RS22475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS22480	COG2190	(PTS) system
BCOA_RS22485	COG1174	glycine betaine transport
BCOA_RS22490	COG1125	glycine betaine transport
BCOA_RS22490	COG0517	IMP dehydrogenase activity
BCOA_RS22510	COG0183	Belongs to the thiolase family
BCOA_RS22520	COG3425	synthase
BCOA_RS22575	COG2814	Major facilitator Superfamily
BCOA_RS22575	COG0477	Major facilitator Superfamily
BCOA_RS22590	COG0519	Catalyzes the synthesis of GMP from XMP
BCOA_RS22600	COG2814	Major facilitator Superfamily
BCOA_RS22605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCOA_RS22660	COG0477	Major facilitator Superfamily
BCOA_RS22665	COG0840	transmembrane signaling receptor activity
BCOA_RS22675	COG1695	Transcriptional regulator
BCOA_RS22690	COG0840	transmembrane signaling receptor activity
BCOA_RS22695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BCOA_RS22725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCOA_RS22730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCOA_RS22735	COG4856	YbbR-like protein
BCOA_RS22740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCOA_RS22745	COG5662	AntiSigma factor
BCOA_RS22750	COG1595	DNA-templated transcription, initiation
BCOA_RS22825	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS22830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BCOA_RS22835	COG4988	ABC transporter
BCOA_RS22845	COG1294	oxidase, subunit
BCOA_RS22850	COG1271	oxidase subunit
BCOA_RS22860	COG0726	polysaccharide deacetylase
BCOA_RS22870	COG2194	sulfuric ester hydrolase activity
BCOA_RS22880	COG0489	protein tyrosine kinase activity
BCOA_RS22885	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCOA_RS22895	COG0833	amino acid
BCOA_RS22900	COG0529	Catalyzes the synthesis of activated sulfate
BCOA_RS22905	COG2046	Belongs to the sulfate adenylyltransferase family
BCOA_RS22915	COG0753	catalase activity
BCOA_RS22920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCOA_RS22925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCOA_RS22935	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCOA_RS22940	COG1122	ATPase activity
BCOA_RS22945	COG1122	ATPase activity
BCOA_RS22950	COG0203	ribosomal protein L17
BCOA_RS22955	COG0202	RNA polymerase activity
BCOA_RS22960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCOA_RS22965	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCOA_RS22970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCOA_RS22975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCOA_RS22980	COG0563	adenylate kinase activity
BCOA_RS22985	COG0201	protein transport
BCOA_RS22990	COG0200	Binds to the 23S rRNA
BCOA_RS23000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCOA_RS23005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCOA_RS23010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCOA_RS23015	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCOA_RS23020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCOA_RS23030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCOA_RS23035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCOA_RS23040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCOA_RS23045	COG0255	Belongs to the universal ribosomal protein uL29 family
BCOA_RS23050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCOA_RS23055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCOA_RS23065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCOA_RS23070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCOA_RS23075	COG0089	rRNA binding
BCOA_RS23080	COG0088	Forms part of the polypeptide exit tunnel
BCOA_RS23090	COG0051	transcription antitermination factor activity, RNA binding
BCOA_RS23100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCOA_RS23105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCOA_RS23110	COG0049	tRNA binding
BCOA_RS23115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCOA_RS23120	COG1358	cellular component organization or biogenesis
BCOA_RS23135	COG2813	Specifically methylates the guanine in position
BCOA_RS23140	COG0222	ribosome binding
BCOA_RS23145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCOA_RS23150	COG0081	regulation of translation
BCOA_RS23155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCOA_RS23160	COG0250	Participates in transcription elongation, termination and antitermination
BCOA_RS23165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCOA_RS23170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCOA_RS23180	COG3688	RNA-binding protein containing a PIN domain
BCOA_RS23185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCOA_RS23195	COG0215	cysteine-tRNA ligase activity
BCOA_RS23200	COG1045	serine acetyltransferase
BCOA_RS23205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCOA_RS23215	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCOA_RS23225	COG4956	integral membrane protein (PIN domain superfamily)
BCOA_RS23230	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCOA_RS23235	COG0542	response to heat
BCOA_RS23240	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BCOA_RS23245	COG3880	PFAM UvrB UvrC protein
BCOA_RS23295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCOA_RS23300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCOA_RS23305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCOA_RS23310	COG0590	tRNA wobble adenosine to inosine editing
BCOA_RS23320	COG1388	LysM domain
BCOA_RS23320	COG3858	chitin binding
BCOA_RS23325	COG1428	Deoxynucleoside kinase
BCOA_RS23330	COG1428	Deoxynucleoside kinase
BCOA_RS23340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCOA_RS23345	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BCOA_RS23360	COG0516	GMP reductase activity
BCOA_RS23360	COG0517	IMP dehydrogenase activity
BCOA_RS23440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCOA_RS23445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCOA_RS23450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCOA_RS23455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCOA_RS23465	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCOA_RS23470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCOA_RS23475	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCOA_RS23480	COG0037	tRNA processing
BCOA_RS23485	COG0515	serine threonine protein kinase
BCOA_RS23490	COG2304	oxidoreductase activity
BCOA_RS23495	COG2208	phosphoserine phosphatase activity
BCOA_RS23505	COG1098	S1 RNA binding domain
BCOA_RS23525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCOA_RS23530	COG3956	TIGRFAM MazG family protein
BCOA_RS23535	COG2244	polysaccharide biosynthetic process
BCOA_RS23540	COG2002	toxin-antitoxin pair type II binding
BCOA_RS23545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCOA_RS23555	COG0193	aminoacyl-tRNA hydrolase activity
BCOA_RS23560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCOA_RS23565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCOA_RS23570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCOA_RS23580	COG1136	(ABC) transporter
BCOA_RS23580	COG0577	efflux transmembrane transporter activity
BCOA_RS23600	COG0251	oxidation-reduction process
BCOA_RS23605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCOA_RS23610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCOA_RS23620	COG4466	Protein conserved in bacteria
BCOA_RS23635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCOA_RS23645	COG0084	hydrolase, TatD family'
BCOA_RS23655	COG2002	toxin-antitoxin pair type II binding
BCOA_RS23660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCOA_RS23665	COG2827	Endonuclease containing a URI domain
BCOA_RS23670	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCOA_RS23675	COG4467	Involved in initiation control of chromosome replication
BCOA_RS23680	COG1774	PSP1 C-terminal conserved region
BCOA_RS23685	COG0470	DNA polymerase III
BCOA_RS23690	COG1728	Protein conserved in bacteria
BCOA_RS23695	COG3870	Protein conserved in bacteria
BCOA_RS23705	COG1982	Orn Lys Arg decarboxylase major
BCOA_RS23740	COG3437	response regulator, receiver
BCOA_RS23745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCOA_RS23750	COG0187	DNA topoisomerase II activity
BCOA_RS23760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCOA_RS23765	COG2501	S4 domain
BCOA_RS23770	COG0592	DNA-directed DNA polymerase activity
BCOA_RS23775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCOA_RS23785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCOA_RS23790	COG0594	ribonuclease P activity
BCOA_RS23795	COG0706	membrane insertase activity
BCOA_RS23800	COG1847	R3H domain protein
BCOA_RS23805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCOA_RS23810	COG0445	tRNA wobble uridine modification
BCOA_RS23815	COG0357	Ribosomal RNA small subunit methyltransferase G
BCOA_RS23820	COG1475	DNA binding
BCOA_RS23830	COG1192	Involved in chromosome partitioning
BCOA_RS23835	COG1475	DNA binding
BCOA_RS23840	COG1811	Na channel or pump
BCOA_RS23855	COG0668	transmembrane transport
BCOA_RS23860	COG4481	Protein conserved in bacteria
BCOA_RS23865	COG0012	GTP binding
BCOA_RS23870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCOA_RS23870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCOA_RS23875	COG0307	riboflavin synthase, alpha
BCOA_RS23880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCOA_RS23880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCOA_RS23885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BCOA_RS23890	COG0360	Binds together with S18 to 16S ribosomal RNA
BCOA_RS23900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCOA_RS23910	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BCOA_RS23915	COG0359	binds to the 23S rRNA
BCOA_RS23920	COG0305	Participates in initiation and elongation during chromosome replication
BCOA_RS23925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCOA_RS23940	COG0745	RESPONSE REGULATOR receiver
BCOA_RS23945	COG5002	protein histidine kinase activity
BCOA_RS23950	COG4863	YycH protein
BCOA_RS23955	COG4853	Protein conserved in bacteria
BCOA_RS23960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCOA_RS23965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCOA_RS23970	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCOA_RS24010	COG2197	response regulator
BCOA_RS24015	COG4585	Histidine kinase
BCOA_RS24020	COG0842	Transport permease protein
BCOA_RS24025	COG1131	(ABC) transporter
BCOA_RS24030	COG0477	Major facilitator Superfamily
BCOA_RS24035	COG0579	oxidoreductase
BCOA_RS24050	COG0765	amino acid transport
BCOA_RS24060	COG1126	abc transporter atp-binding protein
BCOA_RS24070	COG3457	Alanine racemase
BCOA_RS24095	COG1366	Belongs to the anti-sigma-factor antagonist family
BCOA_RS24100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BCOA_RS24105	COG2188	Transcriptional regulator
BCOA_RS24125	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCOA_RS24135	COG1132	(ABC) transporter
BCOA_RS24140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCOA_RS24145	COG0028	Belongs to the TPP enzyme family
BCOA_RS24165	COG2814	Major facilitator Superfamily
BCOA_RS24175	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCOA_RS24180	COG1442	glycosyl transferase family 8
BCOA_RS24185	COG0534	Mate efflux family protein
BCOA_RS24200	COG1119	ATPase activity
BCOA_RS24205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCOA_RS24210	COG2011	ABC-type metal ion transport system permease component
BCOA_RS24215	COG1464	Belongs to the NlpA lipoprotein family
BCOA_RS24220	COG3275	phosphorelay sensor kinase activity
BCOA_RS24230	COG1966	Carbon starvation protein
BCOA_RS24235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCOA_RS24240	COG2966	Psort location CytoplasmicMembrane, score
BCOA_RS24265	COG0367	asparagine synthase
BCOA_RS24270	COG0583	DNA-binding transcription factor activity
BCOA_RS24275	COG1380	Effector of murein hydrolase LrgA
BCOA_RS24280	COG1346	cytolysis
BCOA_RS24285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCOA_RS24295	COG0745	RESPONSE REGULATOR receiver
BCOA_RS24300	COG3850	Histidine kinase
BCOA_RS24300	COG5002	protein histidine kinase activity
BCOA_RS24310	COG1737	Transcriptional regulator
BCOA_RS24315	COG1785	Belongs to the alkaline phosphatase family
BCOA_RS24320	COG0514	ATP-dependent DNA helicase (RecQ)
BCOA_RS24325	COG0561	phosphatase activity
BCOA_RS24340	COG0351	phosphomethylpyrimidine kinase
BCOA_RS24360	COG4555	ABC transporter
BCOA_RS24380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCOA_RS24390	COG2363	Small membrane protein
BCOA_RS24400	COG3253	May function as heme-dependent peroxidase
BCOA_RS24405	COG0280	phosphate acetyltransferase
BCOA_RS24410	COG0095	Lipoate-protein ligase
BCOA_RS24420	COG1078	dGTPase activity
BCOA_RS24425	COG3465	dGTPase activity
BCOA_RS24435	COG1994	Peptidase M50
BCOA_RS24445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCOA_RS24450	COG0010	Belongs to the arginase family
BCOA_RS24460	COG0018	arginyl-trna synthetase
BCOA_RS24465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCOA_RS24470	COG0247	lactate metabolic process
BCOA_RS24470	COG2181	nitrate reductase activity
BCOA_RS24475	COG0183	Belongs to the thiolase family
BCOA_RS24480	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS24485	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS24490	COG1309	transcriptional regulator
BCOA_RS24495	COG1703	isobutyryl-CoA mutase activity
BCOA_RS24495	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCOA_RS24495	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BCOA_RS24505	COG1136	(ABC) transporter
BCOA_RS24515	COG3343	RNA polymerase activity
BCOA_RS24520	COG0504	CTP synthase activity
BCOA_RS24525	COG1725	Transcriptional regulator
BCOA_RS24530	COG1131	(ABC) transporter
BCOA_RS24545	COG2204	response regulator
BCOA_RS24550	COG0191	fructose-bisphosphate aldolase activity
BCOA_RS24555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCOA_RS24560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCOA_RS24565	COG1494	fructose-1,6-bisphosphatase
BCOA_RS24570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCOA_RS24575	COG0254	rRNA binding
BCOA_RS24580	COG1435	thymidine kinase activity
BCOA_RS24590	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCOA_RS24605	COG0009	L-threonylcarbamoyladenylate synthase
BCOA_RS24610	COG1971	Probably functions as a manganese efflux pump
BCOA_RS24630	COG0698	ribose 5-phosphate isomerase
BCOA_RS24640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCOA_RS24650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCOA_RS24665	COG0356	it plays a direct role in the translocation of protons across the membrane
BCOA_RS24670	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCOA_RS24680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCOA_RS24685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCOA_RS24690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCOA_RS24695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCOA_RS24700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCOA_RS24705	COG4836	Membrane
BCOA_RS24715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCOA_RS24725	COG2385	sporulation resulting in formation of a cellular spore
BCOA_RS24730	COG0739	heme binding
BCOA_RS24735	COG1609	Transcriptional regulator
BCOA_RS24740	COG1077	Cell shape determining protein MreB Mrl
BCOA_RS24745	COG4786	Flagellar basal body rod
BCOA_RS24750	COG4786	Flagellar basal body rod
BCOA_RS24755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCOA_RS24760	COG0629	single-stranded DNA binding
BCOA_RS24775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCOA_RS24790	COG1253	flavin adenine dinucleotide binding
BCOA_RS24795	COG0789	Transcriptional regulator
BCOA_RS24800	COG1253	flavin adenine dinucleotide binding
BCOA_RS24815	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCOA_RS24820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCOA_RS24830	COG1554	hydrolase, family 65, central catalytic
BCOA_RS24840	COG3833	ABC-type maltose transport systems, permease component
BCOA_RS24845	COG1175	transmembrane transport
BCOA_RS24850	COG2182	Extracellular solute-binding protein
BCOA_RS24860	COG0366	Alpha amylase catalytic
BCOA_RS24865	COG1609	Transcriptional regulator
BCOA_RS24870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCOA_RS24880	COG1280	lysine exporter protein (LysE YggA)
BCOA_RS24890	COG0513	Belongs to the DEAD box helicase family
BCOA_RS24895	COG0705	Rhomboid family
BCOA_RS24900	COG0736	holo-[acyl-carrier-protein] synthase activity
BCOA_RS24905	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCOA_RS24915	COG0864	Transcriptional regulator
BCOA_RS24920	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCOA_RS24930	COG1366	Belongs to the anti-sigma-factor antagonist family
BCOA_RS24935	COG1366	Belongs to the anti-sigma-factor antagonist family
BCOA_RS24940	COG2172	sigma factor antagonist activity
BCOA_RS24945	COG2208	phosphoserine phosphatase activity
BCOA_RS24950	COG1366	Belongs to the anti-sigma-factor antagonist family
BCOA_RS24955	COG2172	sigma factor antagonist activity
BCOA_RS24960	COG1191	sigma factor activity
BCOA_RS24965	COG2208	phosphoserine phosphatase activity
BCOA_RS24970	COG2183	response to ionizing radiation
BCOA_RS24980	COG3091	SprT-like family
BCOA_RS25065	COG0802	atpase or kinase
BCOA_RS25070	COG1214	PFAM Peptidase M22, glycoprotease
BCOA_RS25075	COG0456	acetyltransferase
BCOA_RS25090	COG0488	(ABC) transporter
BCOA_RS25095	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BCOA_RS25100	COG0805	protein transport
BCOA_RS25110	COG1266	CAAX protease self-immunity
BCOA_RS25115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCOA_RS25120	COG0459	protein refolding
BCOA_RS25125	COG2246	polysaccharide biosynthetic process
BCOA_RS25130	COG0463	Glycosyl transferase, family 2
BCOA_RS25140	COG4948	Mandelate Racemase Muconate Lactonizing
BCOA_RS25145	COG1335	isochorismatase
BCOA_RS25150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCOA_RS25155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCOA_RS25160	COG0519	Catalyzes the synthesis of GMP from XMP
BCOA_RS25160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCOA_RS25175	COG3620	sequence-specific DNA binding
BCOA_RS25195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCOA_RS25200	COG1120	ATPase activity
BCOA_RS25220	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS25230	COG2391	methyltransferase activity
BCOA_RS25240	COG0425	Belongs to the sulfur carrier protein TusA family
BCOA_RS25265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCOA_RS25270	COG1959	2 iron, 2 sulfur cluster binding
BCOA_RS25275	COG2910	NAD(P)H-binding
BCOA_RS25280	COG3479	Phenolic acid decarboxylase
BCOA_RS25285	COG1695	Transcriptional regulator
BCOA_RS25290	COG1725	Transcriptional regulator
BCOA_RS25295	COG1131	(ABC) transporter
BCOA_RS25320	COG0471	metal ion transport
BCOA_RS25330	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCOA_RS25350	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCOA_RS25355	COG1024	Enoyl-CoA hydratase
BCOA_RS25360	COG0183	Belongs to the thiolase family
BCOA_RS25365	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS25370	COG0824	Thioesterase
BCOA_RS25390	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCOA_RS25405	COG0842	Transport permease protein
BCOA_RS25415	COG1131	(ABC) transporter
BCOA_RS25420	COG3850	Histidine kinase
BCOA_RS25425	COG2197	response regulator
BCOA_RS25430	COG2814	Major facilitator Superfamily
BCOA_RS25435	COG1132	(ABC) transporter
BCOA_RS25445	COG2252	PERMEase
BCOA_RS25450	COG3711	transcriptional antiterminator
BCOA_RS25465	COG1301	dicarboxylic acid transport
BCOA_RS25485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCOA_RS25490	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BCOA_RS25500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCOA_RS25505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCOA_RS25510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCOA_RS25520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCOA_RS25525	COG0047	phosphoribosylformylglycinamidine synthase activity
BCOA_RS25530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCOA_RS25535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCOA_RS25540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCOA_RS25545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCOA_RS25550	COG0138	bifunctional purine biosynthesis protein purh
BCOA_RS25555	COG0151	Belongs to the GarS family
BCOA_RS25570	COG1470	cell adhesion involved in biofilm formation
BCOA_RS25575	COG4496	protein, YerC YecD
BCOA_RS25580	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BCOA_RS25585	COG0210	DNA helicase
BCOA_RS25590	COG0210	DNA helicase
BCOA_RS25600	COG4851	CamS sex pheromone cAM373 precursor
BCOA_RS25605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCOA_RS25610	COG2224	Isocitrate lyase
BCOA_RS25615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCOA_RS25620	COG0154	amidase activity
BCOA_RS25625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCOA_RS25655	COG1597	lipid kinase activity
BCOA_RS25660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCOA_RS25730	COG3716	PTS system mannose fructose sorbose family IID component
BCOA_RS25770	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS25785	COG1064	alcohol dehydrogenase
BCOA_RS25800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCOA_RS25810	COG0800	Aldolase
BCOA_RS25830	COG0326	Molecular chaperone. Has ATPase activity
BCOA_RS25840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCOA_RS25845	COG0765	amino acid transport
BCOA_RS25850	COG1126	abc transporter atp-binding protein
BCOA_RS25855	COG1764	response to oxidative stress
BCOA_RS25860	COG2814	Major facilitator Superfamily
BCOA_RS25865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCOA_RS25870	COG1984	allophanate hydrolase subunit 2
BCOA_RS25875	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BCOA_RS25890	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BCOA_RS25900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCOA_RS25910	COG2390	Transcriptional regulator
BCOA_RS25920	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BCOA_RS25935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCOA_RS25960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCOA_RS25965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCOA_RS25970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCOA_RS25975	COG1116	anion transmembrane transporter activity
BCOA_RS25980	COG0431	NADPH-dependent FMN reductase
BCOA_RS25985	COG5583	Uncharacterized small protein (DUF2292)
BCOA_RS25990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCOA_RS25990	COG3153	acetyltransferase
BCOA_RS26030	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS26040	COG0154	amidase activity
BCOA_RS26045	COG2272	Belongs to the type-B carboxylesterase lipase family
BCOA_RS26060	COG1388	LysM domain
BCOA_RS26060	COG0791	NLP P60 protein
BCOA_RS26080	COG1132	(ABC) transporter
BCOA_RS26085	COG1132	(ABC) transporter
BCOA_RS26100	COG3876	Protein conserved in bacteria
BCOA_RS26110	COG1472	Belongs to the glycosyl hydrolase 3 family
BCOA_RS26115	COG0697	spore germination
BCOA_RS26130	COG1278	Cold shock
BCOA_RS26140	COG1691	(AIR) carboxylase
BCOA_RS26145	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BCOA_RS26150	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BCOA_RS26160	COG2610	gluconate transmembrane transporter activity
BCOA_RS26165	COG1606	tRNA processing
BCOA_RS26170	COG2204	response regulator
BCOA_RS26180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCOA_RS26195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCOA_RS26200	COG5002	protein histidine kinase activity
BCOA_RS26215	COG1609	Transcriptional regulator
BCOA_RS26220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCOA_RS26235	COG2372	response to copper ion
BCOA_RS26235	COG1276	copper resistance
BCOA_RS26240	COG4549	nuclear export factor GLE1
BCOA_RS26280	COG1609	Transcriptional regulator
BCOA_RS26285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCOA_RS26290	COG1869	D-ribose catabolic process
BCOA_RS26295	COG1129	ABC transporter
BCOA_RS26300	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCOA_RS26305	COG1879	ABC-type sugar transport system periplasmic component
BCOA_RS26325	COG1929	Belongs to the glycerate kinase type-1 family
BCOA_RS26330	COG1063	alcohol dehydrogenase
BCOA_RS26340	COG1328	CTP reductase activity
BCOA_RS26350	COG1301	dicarboxylic acid transport
BCOA_RS26365	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCOA_RS26405	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCOA_RS26455	COG0517	IMP dehydrogenase activity
BCOA_RS26455	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BCOA_RS26460	COG1263	PTS System
BCOA_RS26460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS26470	COG2190	(PTS) system
BCOA_RS26475	COG0386	Belongs to the glutathione peroxidase family
BCOA_RS26480	COG1280	lysine exporter protein (LysE YggA)
BCOA_RS26505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCOA_RS26510	COG1401	restriction endodeoxyribonuclease activity
BCOA_RS26515	COG4268	DNA restriction-modification system
BCOA_RS26565	COG5444	nuclease activity
BCOA_RS26600	COG0753	catalase activity
BCOA_RS26645	COG3588	fructose-bisphosphate aldolase
BCOA_RS26655	COG0471	metal ion transport
BCOA_RS26660	COG0281	malic enzyme
BCOA_RS26665	COG2223	nitrite transmembrane transporter activity
BCOA_RS26670	COG2181	nitrate reductase activity
BCOA_RS26680	COG1140	nitrate reductase beta subunit
BCOA_RS26685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCOA_RS26725	COG0833	amino acid
BCOA_RS26735	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BCOA_RS26760	COG3829	transcription factor binding
BCOA_RS26765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCOA_RS26785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCOA_RS26790	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS26795	COG0439	Biotin carboxylase
BCOA_RS26800	COG0511	ligase activity, forming carbon-carbon bonds
BCOA_RS26805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCOA_RS26815	COG1024	Enoyl-CoA hydratase
BCOA_RS26820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCOA_RS26845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCOA_RS26850	COG0210	DNA helicase
BCOA_RS26855	COG2233	PERMEase
BCOA_RS26860	COG0730	response to heat
BCOA_RS26865	COG1113	amino acid transport
BCOA_RS26870	COG0778	Nitroreductase
BCOA_RS26950	COG2376	Dihydroxyacetone kinase
BCOA_RS26955	COG1461	Dihydroxyacetone kinase
BCOA_RS26960	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BCOA_RS26965	COG0667	Aldo Keto reductase
BCOA_RS26970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCOA_RS26975	COG2357	RelA SpoT domain protein
BCOA_RS26990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCOA_RS26995	COG2814	Major facilitator Superfamily
BCOA_RS27010	COG0561	phosphatase activity
BCOA_RS27030	COG0371	Dehydrogenase
BCOA_RS27035	COG1349	DNA-binding transcription factor activity
BCOA_RS27040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCOA_RS27040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCOA_RS27040	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCOA_RS27045	COG0025	NhaP-type Na H and K H
BCOA_RS27050	COG0166	Belongs to the GPI family
BCOA_RS27055	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BCOA_RS27060	COG1304	FMN binding
BCOA_RS27110	COG1518	maintenance of DNA repeat elements
BCOA_RS27120	COG1518	maintenance of DNA repeat elements
BCOA_RS27125	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BCOA_RS27155	COG3620	sequence-specific DNA binding
BCOA_RS27175	COG0737	Belongs to the 5'-nucleotidase family
BCOA_RS27180	COG1737	Transcriptional regulator
BCOA_RS27185	COG4086	secreted protein
BCOA_RS27205	COG2197	response regulator
BCOA_RS27215	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCOA_RS27220	COG0288	reversible hydration of carbon dioxide
BCOA_RS27225	COG2226	methyltransferase
BCOA_RS27230	COG1854	S-ribosylhomocysteine lyase activity
BCOA_RS27235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCOA_RS27240	COG0626	cystathionine gamma-synthase activity
BCOA_RS27245	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCOA_RS27250	COG2268	Band 7 protein
BCOA_RS27255	COG1077	Cell shape determining protein MreB Mrl
BCOA_RS27260	COG1607	acyl-coa hydrolase
BCOA_RS27265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCOA_RS27275	COG3189	MarR family transcriptional regulator
BCOA_RS27285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCOA_RS27290	COG1360	Flagellar Motor Protein
BCOA_RS27295	COG0693	protein deglycase activity
BCOA_RS27300	COG0024	Methionine aminopeptidase
BCOA_RS27305	COG4840	Belongs to the UPF0435 family
BCOA_RS27310	COG1295	ribonuclease BN
BCOA_RS27315	COG0477	Major facilitator Superfamily
BCOA_RS27320	COG0387	Pfam Sodium calcium exchanger
BCOA_RS27345	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCOA_RS27350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCOA_RS27420	COG0798	PFAM Bile acid sodium symporter
BCOA_RS27440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCOA_RS27445	COG1846	Transcriptional regulator
BCOA_RS27450	COG1132	(ABC) transporter
BCOA_RS27455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCOA_RS27475	COG0840	transmembrane signaling receptor activity
BCOA_RS27480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCOA_RS27485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCOA_RS27490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCOA_RS27500	COG0477	Major facilitator Superfamily
BCOA_RS27505	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BCOA_RS27535	COG2839	Protein conserved in bacteria
BCOA_RS27540	COG1823	symporter activity
BCOA_RS27555	COG3655	Transcriptional regulator
BCOA_RS27560	COG3739	integral membrane protein
BCOA_RS27565	COG0840	transmembrane signaling receptor activity
BCOA_RS27565	COG5278	phosphoserine phosphatase activity
BCOA_RS27600	COG1511	domain protein
BCOA_RS27610	COG1309	transcriptional regulator
BCOA_RS27615	COG2132	Multicopper oxidase
BCOA_RS27620	COG0252	asparaginase activity
BCOA_RS27625	COG3275	phosphorelay sensor kinase activity
BCOA_RS27630	COG3279	Response regulator of the LytR AlgR family
BCOA_RS27635	COG2223	nitrite transmembrane transporter activity
BCOA_RS27640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCOA_RS27645	COG0670	Belongs to the BI1 family
BCOA_RS27650	COG2124	cytochrome p450
BCOA_RS27660	COG1366	Belongs to the anti-sigma-factor antagonist family
BCOA_RS27670	COG1114	Component of the transport system for branched-chain amino acids
BCOA_RS27680	COG0129	dihydroxy-acid dehydratase activity
BCOA_RS27685	COG0028	Belongs to the TPP enzyme family
BCOA_RS27690	COG0440	acetolactate synthase activity
BCOA_RS27695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCOA_RS27700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCOA_RS27710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCOA_RS27715	COG0066	3-isopropylmalate dehydratase activity
BCOA_RS27720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCOA_RS27735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCOA_RS27740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCOA_RS27745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCOA_RS27750	COG0840	transmembrane signaling receptor activity
BCOA_RS27755	COG0058	SHG alpha-glucan phosphorylase activity
BCOA_RS27765	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS27765	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS27775	COG4585	Histidine kinase
BCOA_RS27780	COG2197	response regulator
BCOA_RS27820	COG1131	(ABC) transporter
BCOA_RS27840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BCOA_RS27845	COG1136	(ABC) transporter
BCOA_RS27845	COG0577	efflux transmembrane transporter activity
BCOA_RS27850	COG0577	efflux transmembrane transporter activity
BCOA_RS27860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCOA_RS27860	COG0512	Glutamine amidotransferase of anthranilate synthase
BCOA_RS27865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCOA_RS27870	COG0134	indole-3-glycerol-phosphate synthase activity
BCOA_RS27880	COG0159	tryptophan synthase activity
BCOA_RS27915	COG1194	a g-specific adenine glycosylase
BCOA_RS27920	COG1988	membrane-bound metal-dependent
BCOA_RS27930	COG1131	(ABC) transporter
BCOA_RS27945	COG0493	'glutamate synthase
BCOA_RS27950	COG0069	glutamate synthase activity
BCOA_RS27950	COG0070	glutamate synthase
BCOA_RS27950	COG0067	glutamate synthase
BCOA_RS27955	COG0583	DNA-binding transcription factor activity
BCOA_RS27960	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS27975	COG3557	Belongs to the UPF0374 family
BCOA_RS27980	COG1132	(ABC) transporter
BCOA_RS27990	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCOA_RS27995	COG1263	PTS System
BCOA_RS27995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCOA_RS28000	COG1737	Transcriptional regulator
BCOA_RS28005	COG4129	membrane
BCOA_RS28020	COG2814	Major facilitator Superfamily
BCOA_RS28025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCOA_RS28030	COG1116	anion transmembrane transporter activity
BCOA_RS28035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCOA_RS28040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCOA_RS28045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCOA_RS28065	COG0735	belongs to the Fur family
BCOA_RS28070	COG0583	DNA-binding transcription factor activity
BCOA_RS28075	COG0028	Belongs to the TPP enzyme family
BCOA_RS28080	COG3527	Alpha-acetolactate decarboxylase
BCOA_RS28190	COG2323	membrane
BCOA_RS28195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCOA_RS28210	COG0697	spore germination
BCOA_RS28215	COG2271	Major facilitator Superfamily
BCOA_RS28230	COG1846	Transcriptional regulator
BCOA_RS28235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCOA_RS28260	COG3850	Histidine kinase
BCOA_RS28260	COG5002	protein histidine kinase activity
BCOA_RS28265	COG0745	RESPONSE REGULATOR receiver
BCOA_RS28290	COG1131	(ABC) transporter
BCOA_RS28305	COG0431	NADPH-dependent FMN reductase
BCOA_RS28310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCOA_RS28315	COG1882	Formate acetyltransferase
BCOA_RS28325	COG2116	formate transmembrane transporter activity
BCOA_RS28330	COG1126	abc transporter atp-binding protein
BCOA_RS28335	COG0765	amino acid transport
BCOA_RS28340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCOA_RS28345	COG0596	Alpha beta hydrolase
BCOA_RS28350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BCOA_RS28365	COG2095	MarC family integral membrane protein
BCOA_RS28380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCOA_RS28395	COG2766	serine protein kinase
BCOA_RS28400	COG2718	Belongs to the UPF0229 family
BCOA_RS28415	COG0306	phosphate transporter
BCOA_RS28420	COG1392	Phosphate transport regulator
BCOA_RS28445	COG3594	Acyltransferase
BCOA_RS28450	COG2719	SpoVR family
BCOA_RS28465	COG0598	Magnesium transport protein CorA
BCOA_RS28475	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BCOA_RS28480	COG0601	transmembrane transport
BCOA_RS28485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCOA_RS28490	COG0444	Belongs to the ABC transporter superfamily
BCOA_RS28495	COG4166	transmembrane transport
BCOA_RS28500	COG0791	NLP P60 protein
BCOA_RS28505	COG4608	Belongs to the ABC transporter superfamily
BCOA_RS28515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCOA_RS28545	COG0840	transmembrane signaling receptor activity
BCOA_RS28555	COG3383	formate dehydrogenase (NAD+) activity
BCOA_RS28570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCOA_RS28590	COG0126	phosphoglycerate kinase activity
BCOA_RS28600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BCOA_RS28605	COG0148	phosphopyruvate hydratase activity
BCOA_RS28610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCOA_RS28615	COG1647	Serine aminopeptidase, S33
BCOA_RS28620	COG0557	exoribonuclease II activity
BCOA_RS28675	COG1414	Transcriptional regulator
BCOA_RS28680	COG0800	Aldolase
BCOA_RS28690	COG0246	Mannitol dehydrogenase
BCOA_RS28695	COG2721	sulfolactate sulfo-lyase activity
BCOA_RS28700	COG1904	glucuronate isomerase
BCOA_RS28705	COG2211	Major facilitator Superfamily
BCOA_RS28710	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS28715	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BCOA_RS28725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCOA_RS28750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCOA_RS28755	COG1595	DNA-templated transcription, initiation
BCOA_RS28775	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCOA_RS28785	COG0671	phosphoesterase, PA-phosphatase related
BCOA_RS28790	COG0753	catalase activity
BCOA_RS28795	COG2200	EAL domain
BCOA_RS28795	COG2202	Pas domain
BCOA_RS28795	COG2199	diguanylate cyclase activity
BCOA_RS28810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCOA_RS28820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCOA_RS28825	COG0772	Belongs to the SEDS family
BCOA_RS28830	COG5577	PFAM Coat F domain
BCOA_RS28850	COG1024	Enoyl-CoA hydratase
BCOA_RS28850	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCOA_RS28855	COG0183	Belongs to the thiolase family
BCOA_RS28860	COG1960	acyl-CoA dehydrogenase activity
BCOA_RS28865	COG1393	Belongs to the ArsC family
BCOA_RS28870	COG0509	glycine decarboxylation via glycine cleavage system
BCOA_RS28875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCOA_RS28890	COG0396	ATPase activity
BCOA_RS28895	COG0719	Fe-S assembly protein
BCOA_RS28900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCOA_RS28905	COG0822	iron-sulfur transferase activity
BCOA_RS28910	COG0719	Fe-S assembly protein
BCOA_RS28915	COG0737	Belongs to the 5'-nucleotidase family
BCOA_RS28920	COG3377	Domain of unknown function (DUF1805)
BCOA_RS28930	COG0739	heme binding
BCOA_RS28935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCOA_RS28940	COG4470	Protein conserved in bacteria
BCOA_RS28945	COG2445	Protein of unknown function DUF86
BCOA_RS28950	COG0647	UMP catabolic process
BCOA_RS28955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCOA_RS28960	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCOA_RS28970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCOA_RS28975	COG4837	Protein of unknown function (DUF1462)
BCOA_RS28980	COG0316	Belongs to the HesB IscA family
BCOA_RS29005	COG0492	ferredoxin-NADP+ reductase activity
BCOA_RS29010	COG1252	NADH dehydrogenase
BCOA_RS29020	COG3584	3D domain protein
BCOA_RS29025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCOA_RS29035	COG0697	spore germination
BCOA_RS29045	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCOA_RS29060	COG2050	protein possibly involved in aromatic compounds catabolism
BCOA_RS29065	COG2814	Major facilitator Superfamily
BCOA_RS29090	COG0492	ferredoxin-NADP+ reductase activity
BCOA_RS29100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCOA_RS29115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCOA_RS29140	COG0656	L-ascorbic acid biosynthetic process
BCOA_RS29160	COG1098	S1 RNA binding domain
BCOA_RS29175	COG2155	Conserved Protein
BCOA_RS29185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCOA_RS29205	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS29220	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BCOA_RS29225	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS29240	COG0840	transmembrane signaling receptor activity
BCOA_RS29250	COG1609	Transcriptional regulator
BCOA_RS29260	COG2160	L-arabinose isomerase activity
BCOA_RS29265	COG4214	carbohydrate transport
BCOA_RS29275	COG4213	ABC transporter substrate-binding protein
BCOA_RS29280	COG1609	Transcriptional regulator
BCOA_RS29305	COG2160	L-arabinose isomerase activity
BCOA_RS29310	COG0235	Class ii aldolase
BCOA_RS29325	COG2190	(PTS) system
BCOA_RS29330	COG1525	nuclease
BCOA_RS29340	COG1937	Protein conserved in bacteria
BCOA_RS29345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCOA_RS29345	COG0425	Belongs to the sulfur carrier protein TusA family
BCOA_RS29350	COG0038	chloride channel
BCOA_RS29370	COG0726	polysaccharide deacetylase
BCOA_RS29380	COG4221	oxidoreductase activity
BCOA_RS29385	COG1388	LysM domain
BCOA_RS29390	COG0745	RESPONSE REGULATOR receiver
BCOA_RS29395	COG5002	protein histidine kinase activity
BCOA_RS29420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCOA_RS29440	COG1522	sequence-specific DNA binding
BCOA_RS29460	COG2608	mercury ion transmembrane transporter activity
BCOA_RS29465	COG2217	Heavy metal translocating P-type atpase
BCOA_RS29480	COG1285	pathogenesis
BCOA_RS29630	COG1575	Belongs to the MenA family. Type 1 subfamily
BCOA_RS29635	COG1169	isochorismate synthase
BCOA_RS29640	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BCOA_RS29645	COG0596	Alpha beta hydrolase
BCOA_RS29650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCOA_RS29655	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS29660	COG4948	Mandelate Racemase Muconate Lactonizing
BCOA_RS29665	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCOA_RS29670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCOA_RS29675	COG0783	Belongs to the Dps family
BCOA_RS29690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCOA_RS29695	COG1116	anion transmembrane transporter activity
BCOA_RS29700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCOA_RS29705	COG1070	Carbohydrate kinase
BCOA_RS29710	COG0655	NAD(P)H dehydrogenase (quinone) activity
BCOA_RS29715	COG1506	peptidase
BCOA_RS29725	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BCOA_RS29730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCOA_RS29735	COG0367	asparagine synthase
BCOA_RS29740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCOA_RS29745	COG2267	carboxylic ester hydrolase activity
BCOA_RS29760	COG0275	rRNA processing
BCOA_RS29770	COG2814	Major facilitator Superfamily
BCOA_RS29775	COG0495	leucyl-tRNA aminoacylation
BCOA_RS29795	COG2244	polysaccharide biosynthetic process
BCOA_RS29800	COG1349	DNA-binding transcription factor activity
BCOA_RS29810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCOA_RS29830	COG0510	thiamine kinase activity
BCOA_RS29840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCOA_RS29845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCOA_RS29850	COG5584	Small secreted protein
BCOA_RS29855	COG1363	Peptidase, m42
BCOA_RS29860	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BCOA_RS29885	COG5002	protein histidine kinase activity
BCOA_RS29885	COG0784	Response regulator, receiver
BCOA_RS29895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCOA_RS29900	COG2208	phosphoserine phosphatase activity
BCOA_RS29905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCOA_RS29910	COG4848	Belongs to the UPF0354 family
BCOA_RS29915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCOA_RS29925	COG1674	ftsk spoiiie
BCOA_RS29930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCOA_RS29940	COG4980	gas vesicle protein
BCOA_RS29945	COG1605	Chorismate mutase
BCOA_RS29945	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCOA_RS29955	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCOA_RS29960	COG0517	IMP dehydrogenase activity
BCOA_RS29965	COG0454	-acetyltransferase
BCOA_RS29970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCOA_RS29980	COG4149	molybdate abc transporter
BCOA_RS29985	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BCOA_RS29990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCOA_RS30005	COG0303	'Molybdopterin
BCOA_RS30010	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCOA_RS30015	COG0314	molybdopterin synthase activity
BCOA_RS30020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BCOA_RS30025	COG0315	cyclic pyranopterin monophosphate synthase activity
BCOA_RS30030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCOA_RS30035	COG2427	Protein of unknown function (DUF1641)
BCOA_RS30040	COG3383	formate dehydrogenase (NAD+) activity
BCOA_RS30045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCOA_RS30060	COG3290	protein histidine kinase activity
BCOA_RS30060	COG3829	transcription factor binding
BCOA_RS30065	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS30070	COG0506	proline dehydrogenase activity
BCOA_RS30085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCOA_RS30090	COG2199	diguanylate cyclase activity
BCOA_RS30090	COG2203	Gaf domain
BCOA_RS30095	COG1956	GAF domain-containing protein
BCOA_RS30100	COG1309	transcriptional regulator
BCOA_RS30105	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BCOA_RS30110	COG1104	cysteine desulfurase activity
BCOA_RS30115	COG0301	tRNA thio-modification
BCOA_RS30125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCOA_RS30130	COG0616	signal peptide processing
BCOA_RS30135	COG1714	RDD family
BCOA_RS30145	COG3874	Sporulation protein YtfJ
BCOA_RS30150	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCOA_RS30155	COG0827	DNA restriction-modification system
BCOA_RS30160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCOA_RS30170	COG0589	response to stress
BCOA_RS30180	COG0006	proline dipeptidase activity
BCOA_RS30185	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCOA_RS30190	COG4109	DRTGG domain
BCOA_RS30200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCOA_RS30215	COG0587	DNA-directed DNA polymerase activity
BCOA_RS30220	COG0281	malic enzyme
BCOA_RS30225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCOA_RS30230	COG0825	malonyl-CoA metabolic process
BCOA_RS30235	COG0205	6-phosphofructokinase activity
BCOA_RS30245	COG0628	permease
BCOA_RS30250	COG2707	UPF0756 membrane protein
BCOA_RS30255	COG0372	Belongs to the citrate synthase family
BCOA_RS30260	COG0538	isocitrate dehydrogenase activity
BCOA_RS30265	COG0039	L-malate dehydrogenase activity
BCOA_RS30275	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCOA_RS30275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCOA_RS30280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCOA_RS30285	COG1971	Probably functions as a manganese efflux pump
BCOA_RS30290	COG0237	dephospho-CoA kinase activity
BCOA_RS30295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCOA_RS30310	COG1473	amidohydrolase
BCOA_RS30315	COG0747	negative chemotaxis
BCOA_RS30320	COG0601	transmembrane transport
BCOA_RS30330	COG0444	Belongs to the ABC transporter superfamily
BCOA_RS30335	COG4608	Belongs to the ABC transporter superfamily
BCOA_RS30360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BCOA_RS30365	COG3611	Membrane attachment protein
BCOA_RS30370	COG1484	DNA-dependent DNA replication
BCOA_RS30380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCOA_RS30390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCOA_RS30400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCOA_RS30430	COG0431	NADPH-dependent FMN reductase
BCOA_RS30450	COG1695	Transcriptional regulator
BCOA_RS30460	COG2329	Antibiotic biosynthesis monooxygenase
BCOA_RS30495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCOA_RS30500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCOA_RS30505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCOA_RS30505	COG0072	phenylalanine-tRNA ligase activity
BCOA_RS30515	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BCOA_RS30520	COG1286	toxin biosynthetic process
BCOA_RS30525	COG1796	DNA polymerase
BCOA_RS30525	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCOA_RS30530	COG1193	negative regulation of DNA recombination
BCOA_RS30535	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS30540	COG1309	transcriptional regulator
BCOA_RS30545	COG1024	Enoyl-CoA hydratase
BCOA_RS30550	COG2086	electron transfer activity
BCOA_RS30555	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCOA_RS30560	COG3118	belongs to the thioredoxin family
BCOA_RS30565	COG0322	excinuclease ABC activity
BCOA_RS30580	COG1719	4-vinyl reductase, 4VR
BCOA_RS30585	COG2009	succinate dehydrogenase
BCOA_RS30590	COG1053	succinate dehydrogenase
BCOA_RS30595	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCOA_RS30600	COG0824	Thioesterase
BCOA_RS30605	COG2197	response regulator
BCOA_RS30635	COG1846	Transcriptional regulator
BCOA_RS30650	COG5577	PFAM Coat F domain
BCOA_RS30655	COG1063	alcohol dehydrogenase
BCOA_RS30660	COG5577	PFAM Coat F domain
BCOA_RS30670	COG5401	PFAM Sporulation and spore germination
BCOA_RS30675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BCOA_RS30680	COG0622	Phosphoesterase
BCOA_RS30705	COG0457	Tetratricopeptide repeat
BCOA_RS30705	COG1477	protein flavinylation
BCOA_RS30710	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCOA_RS30720	COG1067	ATP-dependent peptidase activity
BCOA_RS30720	COG0470	DNA polymerase III
BCOA_RS30725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BCOA_RS30730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCOA_RS30745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCOA_RS30750	COG0181	hydroxymethylbilane synthase activity
BCOA_RS30765	COG0113	porphobilinogen synthase activity
BCOA_RS30770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCOA_RS30775	COG1388	LysM domain
BCOA_RS30775	COG1388	LysM domain
BCOA_RS30780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCOA_RS30795	COG0285	dihydrofolate synthase activity
BCOA_RS30830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCOA_RS30840	COG1459	type II secretion system
BCOA_RS30865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCOA_RS30875	COG2003	Belongs to the UPF0758 family
BCOA_RS30885	COG1792	Involved in formation and maintenance of cell shape
BCOA_RS30895	COG0850	regulation of cytokinetic process
BCOA_RS30900	COG2894	cell division
BCOA_RS30910	COG1994	Peptidase M50
BCOA_RS30915	COG1530	ribonuclease E activity
BCOA_RS30920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCOA_RS30925	COG2868	ribosomal protein
BCOA_RS30930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCOA_RS30935	COG3290	protein histidine kinase activity
BCOA_RS30940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCOA_RS30945	COG4492	Belongs to the UPF0735 family
BCOA_RS30950	COG0077	Prephenate dehydratase
BCOA_RS30955	COG1827	regulation of RNA biosynthetic process
BCOA_RS30960	COG1388	LysM domain
BCOA_RS30970	COG0217	transcriptional regulatory protein
BCOA_RS31000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCOA_RS31005	COG0343	queuine tRNA-ribosyltransferase activity
BCOA_RS31010	COG1862	Preprotein translocase
BCOA_RS31020	COG2323	membrane
BCOA_RS31025	COG2244	polysaccharide biosynthetic process
BCOA_RS31040	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCOA_RS31040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCOA_RS31045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCOA_RS31050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCOA_RS31055	COG1490	D-aminoacyl-tRNA deacylase activity
BCOA_RS31060	COG1846	Transcriptional regulator
BCOA_RS31065	COG1566	PFAM secretion protein HlyD family protein
BCOA_RS31070	COG2814	Major facilitator Superfamily
BCOA_RS31075	COG4991	sh3 domain protein
BCOA_RS31075	COG3103	Sh3 type 3 domain protein
BCOA_RS31075	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCOA_RS31080	COG0124	histidyl-tRNA synthetase
BCOA_RS31085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCOA_RS31090	COG0385	Bile acid
BCOA_RS31095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCOA_RS31100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCOA_RS31105	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS31120	COG1959	2 iron, 2 sulfur cluster binding
BCOA_RS31125	COG1104	cysteine desulfurase activity
BCOA_RS31130	COG0482	sulfurtransferase activity
BCOA_RS31140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCOA_RS31170	COG0628	permease
BCOA_RS31175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCOA_RS31180	COG4472	Bacterial protein of unknown function (DUF965)
BCOA_RS31185	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCOA_RS31190	COG3906	Belongs to the UPF0473 family
BCOA_RS31195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCOA_RS31200	COG4122	O-methyltransferase activity
BCOA_RS31205	COG0572	uridine kinase
BCOA_RS31210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCOA_RS31235	COG0450	alkyl hydroperoxide reductase
BCOA_RS31240	COG3634	alkyl hydroperoxide reductase activity
BCOA_RS31250	COG1183	phosphatidylcholine synthase activity
BCOA_RS31285	COG1704	LemA family
BCOA_RS31295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCOA_RS31305	COG0071	Belongs to the small heat shock protein (HSP20) family
BCOA_RS31310	COG2132	Multicopper oxidase
BCOA_RS31320	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCOA_RS31335	COG2210	Belongs to the sulfur carrier protein TusA family
BCOA_RS31340	COG0071	Belongs to the small heat shock protein (HSP20) family
BCOA_RS31345	COG2132	Multicopper oxidase
BCOA_RS31350	COG3835	regulator
BCOA_RS31355	COG0277	FAD linked oxidase domain protein
BCOA_RS31360	COG0247	lactate metabolic process
BCOA_RS31365	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BCOA_RS31370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCOA_RS31375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCOA_RS31380	COG1534	Rna-binding protein
BCOA_RS31385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCOA_RS31390	COG1713	HD superfamily hydrolase involved in NAD metabolism
BCOA_RS31395	COG0799	negative regulation of ribosome biogenesis
BCOA_RS31400	COG2226	methyltransferase
BCOA_RS31405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCOA_RS31410	COG1596	polysaccharide export
BCOA_RS31410	COG1555	photosystem II stabilization
BCOA_RS31415	COG2131	deaminase
BCOA_RS31420	COG0658	competence protein
BCOA_RS31420	COG2333	competence protein COMEC
BCOA_RS31430	COG1466	dna polymerase III delta subunit
BCOA_RS31435	COG0268	Binds directly to 16S ribosomal RNA
BCOA_RS31440	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCOA_RS31445	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCOA_RS31450	COG0481	GTPase activity
BCOA_RS31455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCOA_RS31465	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCOA_RS31470	COG0443	Heat shock 70 kDa protein
BCOA_RS31480	COG2264	protein methyltransferase activity
BCOA_RS31485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCOA_RS31490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCOA_RS31495	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCOA_RS31510	COG1610	YqeY-like protein
BCOA_RS31525	COG1702	phosphate starvation-inducible protein PhoH
BCOA_RS31530	COG1480	7TM receptor with intracellular HD hydrolase
BCOA_RS31535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCOA_RS31540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCOA_RS31550	COG1381	Involved in DNA repair and RecF pathway recombination
BCOA_RS31555	COG0517	IMP dehydrogenase activity
BCOA_RS31565	COG0358	DNA primase activity
BCOA_RS31570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCOA_RS31580	COG2010	Cytochrome c
BCOA_RS31585	COG2384	SAM-dependent methyltransferase
BCOA_RS31590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCOA_RS31595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCOA_RS31605	COG0513	Belongs to the DEAD box helicase family
BCOA_RS31610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BCOA_RS31615	COG3883	PFAM NLP P60 protein
BCOA_RS31615	COG0791	NLP P60 protein
BCOA_RS31625	COG1121	(ABC) transporter
BCOA_RS31630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCOA_RS31635	COG0735	belongs to the Fur family
BCOA_RS31640	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BCOA_RS31645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCOA_RS31655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCOA_RS31660	COG0477	Major facilitator Superfamily
BCOA_RS31665	COG0768	penicillin binding
BCOA_RS31675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCOA_RS31680	COG0457	Tetratricopeptide repeat
BCOA_RS31680	COG0705	Rhomboid family
BCOA_RS31685	COG4483	Protein conserved in bacteria
BCOA_RS31690	COG1940	carbohydrate kinase activity
BCOA_RS31700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCOA_RS31715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCOA_RS31720	COG1459	type II secretion system
BCOA_RS31725	COG4537	Required for transformation and DNA binding
BCOA_RS31750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCOA_RS31760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCOA_RS31765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCOA_RS31775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCOA_RS31780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCOA_RS31785	COG0095	Lipoate-protein ligase
BCOA_RS31790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCOA_RS31795	COG0492	ferredoxin-NADP+ reductase activity
BCOA_RS31800	COG1024	Enoyl-CoA hydratase
BCOA_RS31805	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS31810	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCOA_RS31815	COG0183	Belongs to the thiolase family
BCOA_RS31820	COG3327	negative regulation of DNA-templated transcription, initiation
BCOA_RS31830	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCOA_RS31840	COG3872	metal-dependent enzyme
BCOA_RS31850	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCOA_RS31855	COG0006	proline dipeptidase activity
BCOA_RS31860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCOA_RS31865	COG3854	ATPases associated with a variety of cellular activities
BCOA_RS31905	COG0511	ligase activity, forming carbon-carbon bonds
BCOA_RS31910	COG0439	Biotin carboxylase
BCOA_RS31915	COG1302	Protein conserved in bacteria
BCOA_RS31930	COG1570	exodeoxyribonuclease VII activity
BCOA_RS31945	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCOA_RS31950	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BCOA_RS31960	COG0497	DNA recombination
BCOA_RS31965	COG0750	zinc metalloprotease
BCOA_RS31975	COG0745	RESPONSE REGULATOR receiver
BCOA_RS31980	COG0584	glycerophosphoryl diester phosphodiesterase
BCOA_RS31990	COG3829	transcription factor binding
BCOA_RS31990	COG3290	protein histidine kinase activity
BCOA_RS31995	COG3290	protein histidine kinase activity
BCOA_RS31995	COG3829	transcription factor binding
BCOA_RS32005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCOA_RS32010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCOA_RS32015	COG0022	dehydrogenase e1 component
BCOA_RS32020	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCOA_RS32025	COG1105	Belongs to the carbohydrate kinase PfkB family
BCOA_RS32035	COG1376	ErfK ybiS ycfS ynhG family protein
BCOA_RS32040	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCOA_RS32050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCOA_RS32055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCOA_RS32065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCOA_RS32070	COG0300	oxidoreductase activity
BCOA_RS32075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCOA_RS32085	COG3858	chitin binding
BCOA_RS32085	COG1388	LysM domain
BCOA_RS32090	COG1073	alpha beta
BCOA_RS32095	COG3853	Toxic anion resistance protein (TelA)
BCOA_RS32100	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BCOA_RS32110	COG0667	Aldo Keto reductase
BCOA_RS32125	COG1379	DNA repair
BCOA_RS32130	COG1300	Membrane
BCOA_RS32135	COG0735	belongs to the Fur family
BCOA_RS32145	COG4974	Belongs to the 'phage' integrase family
BCOA_RS32150	COG1686	Belongs to the peptidase S11 family
BCOA_RS32165	COG1191	sigma factor activity
BCOA_RS32185	COG0697	spore germination
BCOA_RS32205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCOA_RS32210	COG1686	Belongs to the peptidase S11 family
BCOA_RS32215	COG2715	membrane protein required for spore maturation
BCOA_RS32220	COG0700	Nucleoside recognition
BCOA_RS32225	COG1187	pseudouridine synthase activity
BCOA_RS32230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCOA_RS32235	COG1333	cytochrome c biogenesis protein
BCOA_RS32240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCOA_RS32245	COG0745	RESPONSE REGULATOR receiver
BCOA_RS32250	COG5002	protein histidine kinase activity
BCOA_RS32255	COG0739	heme binding
BCOA_RS32255	COG0741	lytic transglycosylase activity
BCOA_RS32255	COG1196	nuclear chromosome segregation
BCOA_RS32260	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCOA_RS32265	COG1141	Ferredoxin
BCOA_RS32275	COG0514	ATP-dependent DNA helicase (RecQ)
BCOA_RS32280	COG1266	CAAX protease self-immunity
BCOA_RS32295	COG3546	catalase activity
BCOA_RS32310	COG1408	metallophosphoesterase
BCOA_RS32320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCOA_RS32325	COG0492	ferredoxin-NADP+ reductase activity
BCOA_RS32330	COG2339	peptidase activity
BCOA_RS32335	COG3409	Peptidoglycan-binding domain 1 protein
BCOA_RS32335	COG3773	Cell wall hydrolase
BCOA_RS32345	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BCOA_RS32350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCOA_RS32355	COG0539	negative regulation of cytoplasmic translation
BCOA_RS32365	COG1160	GTP binding
BCOA_RS32385	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCOA_RS32390	COG0776	regulation of translation
BCOA_RS32400	COG0142	geranyltranstransferase activity
BCOA_RS32405	COG2226	methyltransferase
BCOA_RS32410	COG0142	geranyltranstransferase activity
BCOA_RS32415	COG0105	UTP biosynthetic process
BCOA_RS32420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCOA_RS32425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCOA_RS32430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCOA_RS32435	COG4401	Chorismate mutase type I
BCOA_RS32440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCOA_RS32445	COG0287	Prephenate dehydrogenase
BCOA_RS32450	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCOA_RS32455	COG0457	Tetratricopeptide repeat
BCOA_RS32460	COG5582	Belongs to the UPF0302 family
BCOA_RS32475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCOA_RS32485	COG4347	Protein of unknown function (DUF1405)
BCOA_RS32495	COG2738	Putative neutral zinc metallopeptidase
BCOA_RS32505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCOA_RS32510	COG1694	Mazg nucleotide pyrophosphohydrolase
BCOA_RS32515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCOA_RS32520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCOA_RS32525	COG0438	transferase activity, transferring glycosyl groups
BCOA_RS32545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCOA_RS32550	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCOA_RS32555	COG1199	ATP-dependent helicase activity
BCOA_RS32555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCOA_RS32570	COG0017	Asparaginyl-tRNA synthetase
BCOA_RS32575	COG3344	reverse transcriptase
BCOA_RS32585	COG3935	DnaD domain protein
BCOA_RS32590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCOA_RS32605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCOA_RS32605	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCOA_RS32610	COG3331	DNA recombination
BCOA_RS32635	COG0071	Belongs to the small heat shock protein (HSP20) family
BCOA_RS32640	COG1111	helicase
BCOA_RS32640	COG1205	dead DEAH box helicase
BCOA_RS32645	COG3359	exonuclease
BCOA_RS32655	COG4474	Belongs to the UPF0398 family
BCOA_RS32665	COG0116	Belongs to the methyltransferase superfamily
BCOA_RS32670	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCOA_RS32680	COG2233	PERMEase
BCOA_RS32695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCOA_RS32700	COG0789	Transcriptional regulator
BCOA_RS32705	COG0174	glutamine synthetase
BCOA_RS32710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCOA_RS32720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCOA_RS32725	COG4224	UPF0291 protein
BCOA_RS32740	COG3763	UPF0154 protein
BCOA_RS32745	COG0785	Cytochrome C biogenesis protein
BCOA_RS32750	COG2201	protein-glutamate methylesterase activity
BCOA_RS32755	COG4846	Membrane protein involved in cytochrome C biogenesis
BCOA_RS32765	COG0204	Acyl-transferase
BCOA_RS32770	COG2027	D-alanyl-D-alanine carboxypeptidase
BCOA_RS32775	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCOA_RS32795	COG3546	catalase activity
BCOA_RS32810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCOA_RS32815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BCOA_RS32820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCOA_RS32825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCOA_RS32830	COG0505	Belongs to the CarA family
BCOA_RS32835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCOA_RS32840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BCOA_RS32845	COG0137	argininosuccinate synthase activity
BCOA_RS32850	COG0165	Argininosuccinate lyase
BCOA_RS32855	COG0436	Aminotransferase
BCOA_RS32880	COG0789	Transcriptional regulator
BCOA_RS32885	COG4990	cell redox homeostasis
BCOA_RS32895	COG2404	hydrolase activity, acting on ester bonds
BCOA_RS32900	COG1252	NADH dehydrogenase
BCOA_RS32910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCOA_RS32915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCOA_RS32920	COG0701	Predicted permease
BCOA_RS32930	COG0709	Synthesizes selenophosphate from selenide and ATP
BCOA_RS32935	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BCOA_RS32945	COG0277	FAD linked oxidase domain protein
BCOA_RS32950	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS32955	COG2030	dehydratase
BCOA_RS32965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCOA_RS32990	COG1131	(ABC) transporter
BCOA_RS32995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCOA_RS33005	COG0783	Belongs to the Dps family
BCOA_RS33010	COG1914	H( )-stimulated, divalent metal cation uptake system
BCOA_RS33015	COG0494	nUDIX hydrolase
BCOA_RS33020	COG1247	-acetyltransferase
BCOA_RS33040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCOA_RS33045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCOA_RS33050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCOA_RS33055	COG0297	glycogen (starch) synthase activity
BCOA_RS33065	COG0708	Exodeoxyribonuclease III
BCOA_RS33070	COG3773	Cell wall hydrolase
BCOA_RS33075	COG2223	nitrite transmembrane transporter activity
BCOA_RS33080	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS33085	COG0039	L-malate dehydrogenase activity
BCOA_RS33100	COG2322	membrane
BCOA_RS33105	COG0561	phosphatase activity
BCOA_RS33115	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS33120	COG0183	Belongs to the thiolase family
BCOA_RS33135	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BCOA_RS33145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCOA_RS33160	COG1511	domain protein
BCOA_RS33160	COG3264	Mechanosensitive ion channel
BCOA_RS33165	COG3284	Transcriptional regulator
BCOA_RS33170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCOA_RS33175	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCOA_RS33180	COG0022	dehydrogenase e1 component
BCOA_RS33185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCOA_RS33195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCOA_RS33200	COG0789	Transcriptional regulator
BCOA_RS33210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCOA_RS33215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BCOA_RS33220	COG2045	Belongs to the ComB family
BCOA_RS33225	COG1809	phosphosulfolactate synthase activity
BCOA_RS33235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCOA_RS33240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCOA_RS33245	COG2814	Major facilitator Superfamily
BCOA_RS33250	COG1309	transcriptional regulator
BCOA_RS33290	COG2258	MOSC domain
BCOA_RS33310	COG0351	phosphomethylpyrimidine kinase
BCOA_RS33315	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BCOA_RS33320	COG1028	Short-chain dehydrogenase reductase Sdr
BCOA_RS33325	COG0351	phosphomethylpyrimidine kinase
BCOA_RS33330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCOA_RS33340	COG0456	acetyltransferase
BCOA_RS33345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCOA_RS33350	COG0456	acetyltransferase
BCOA_RS33375	COG2226	methyltransferase
BCOA_RS33385	COG0473	3-isopropylmalate dehydrogenase activity
BCOA_RS33395	COG0681	Belongs to the peptidase S26 family
BCOA_RS33405	COG2070	2-Nitropropane dioxygenase
BCOA_RS33430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCOA_RS33430	COG0574	Belongs to the PEP-utilizing enzyme family
BCOA_RS33435	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BCOA_RS33450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCOA_RS33455	COG0187	DNA topoisomerase II activity
BCOA_RS33460	COG1832	CoA-binding protein
BCOA_RS33465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCOA_RS33470	COG4841	protein insertion into membrane
BCOA_RS33480	COG0824	Thioesterase
BCOA_RS33495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCOA_RS33505	COG2309	aminopeptidase activity
BCOA_RS33525	COG0318	PFAM AMP-dependent synthetase and ligase
BCOA_RS33530	COG1346	cytolysis
BCOA_RS33535	COG1380	Effector of murein hydrolase LrgA
BCOA_RS33545	COG1132	(ABC) transporter
BCOA_RS33550	COG1132	(ABC) transporter
BCOA_RS33560	COG0477	Major facilitator Superfamily
BCOA_RS33580	COG1113	amino acid transport
BCOA_RS33585	COG5039	Polysaccharide pyruvyl transferase
BCOA_RS33590	COG2814	Major facilitator Superfamily
BCOA_RS33595	COG0640	Transcriptional regulator
BCOA_RS33625	COG0745	RESPONSE REGULATOR receiver
BCOA_RS33630	COG0642	Histidine kinase
BCOA_RS33635	COG1136	(ABC) transporter
BCOA_RS33640	COG0577	efflux transmembrane transporter activity
BCOA_RS33655	COG3634	alkyl hydroperoxide reductase activity
BCOA_RS33660	COG0302	gtp cyclohydrolase
BCOA_RS33665	COG1278	Cold shock
BCOA_RS33675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCOA_RS33685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCOA_RS33690	COG2807	transmembrane transport
BCOA_RS33710	COG0569	domain protein
BCOA_RS33715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCOA_RS33720	COG2962	Rard protein
BCOA_RS33725	COG2391	methyltransferase activity
BCOA_RS33735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCOA_RS33735	COG0140	phosphoribosyl-ATP diphosphatase activity
BCOA_RS33740	COG0107	imidazoleglycerol-phosphate synthase activity
BCOA_RS33750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCOA_RS33755	COG0131	Imidazoleglycerol-phosphate dehydratase
BCOA_RS33760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCOA_RS33765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCOA_RS33770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BCOA_RS33780	COG0598	Magnesium transport protein CorA
BCOA_RS33785	COG1280	lysine exporter protein (LysE YggA)
BCOA_RS33790	COG1113	amino acid transport
BCOA_RS33795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCOA_RS33800	COG3584	3D domain protein
BCOA_RS33800	COG1388	LysM domain
BCOA_RS33805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCOA_RS33805	COG0723	plastoquinol--plastocyanin reductase activity
BCOA_RS33810	COG0517	IMP dehydrogenase activity
BCOA_RS33810	COG0516	GMP reductase activity
BCOA_RS33815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCOA_RS33825	COG2135	peptidase activity
BCOA_RS33835	COG1054	Belongs to the UPF0176 family
BCOA_RS33845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCOA_RS33865	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS33870	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCOA_RS33875	COG0567	Dehydrogenase, E1 component
BCOA_RS33890	COG0745	RESPONSE REGULATOR receiver
BCOA_RS33900	COG2814	Major facilitator Superfamily
BCOA_RS33905	COG1331	Highly conserved protein containing a thioredoxin domain
BCOA_RS33920	COG1368	sulfuric ester hydrolase activity
BCOA_RS33930	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BCOA_RS33935	COG1793	dna ligase
BCOA_RS33935	COG3285	dna ligase
BCOA_RS33950	COG0534	Mate efflux family protein
BCOA_RS33955	COG2340	Cysteine-rich secretory protein family
BCOA_RS33965	COG1846	Transcriptional regulator
BCOA_RS33970	COG0793	Belongs to the peptidase S41A family
BCOA_RS33970	COG3409	Peptidoglycan-binding domain 1 protein
BCOA_RS33980	COG1876	peptidase activity
BCOA_RS34000	COG4479	Belongs to the UPF0346 family
BCOA_RS34005	COG0840	transmembrane signaling receptor activity
BCOA_RS34010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCOA_RS34015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCOA_RS34020	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BCOA_RS34020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCOA_RS34030	COG2755	lipolytic protein G-D-S-L family
BCOA_RS34035	COG1272	protein, Hemolysin III
BCOA_RS34040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCOA_RS34045	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BCOA_RS34060	COG1413	lyase activity
BCOA_RS34065	COG0488	(ABC) transporter
BCOA_RS34070	COG1418	mRNA catabolic process
BCOA_RS34080	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BCOA_RS34090	COG1321	iron dependent repressor
BCOA_RS34110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCOA_RS34115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BCOA_RS34120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCOA_RS34125	COG0464	growth
BCOA_RS34140	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCOA_RS34170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCOA_RS34175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCOA_RS34185	COG4550	Control of competence regulator ComK, YlbF/YmcA
BCOA_RS34190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCOA_RS34200	COG1012	belongs to the aldehyde dehydrogenase family
BCOA_RS34205	COG3829	transcription factor binding
BCOA_RS34210	COG0531	amino acid
BCOA_RS34215	COG0826	peptidase U32
BCOA_RS34220	COG0826	peptidase U32
BCOA_RS34225	COG2359	stage V sporulation protein S
BCOA_RS34230	COG1692	metallophosphoesterase
BCOA_RS34235	COG1418	mRNA catabolic process
BCOA_RS34250	COG1058	Belongs to the CinA family
BCOA_RS34250	COG1546	Belongs to the CinA family
BCOA_RS34255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCOA_RS34260	COG1426	Protein conserved in bacteria
BCOA_RS34275	COG0300	oxidoreductase activity
BCOA_RS34280	COG0612	Peptidase, M16
BCOA_RS34285	COG0612	Peptidase, M16
BCOA_RS34295	COG1079	Belongs to the binding-protein-dependent transport system permease family
BCOA_RS34300	COG4603	Belongs to the binding-protein-dependent transport system permease family
BCOA_RS34305	COG3845	ABC transporter
BCOA_RS34310	COG1744	ABC transporter substrate-binding protein PnrA-like
BCOA_RS34315	COG4980	gas vesicle protein
BCOA_RS34315	COG1674	ftsk spoiiie
BCOA_RS34325	COG0740	serine-type endopeptidase activity
BCOA_RS34330	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCOA_RS34370	COG4193	domain, Protein