locus-tag	class	description
BF29_RS00005	COG0583	DNA-binding transcription factor activity
BF29_RS00010	COG2171	N-acyltransferase activity
BF29_RS00015	COG1473	amidohydrolase
BF29_RS00020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF29_RS00060	COG1982	Orn Lys Arg decarboxylase major
BF29_RS00080	COG0483	inositol monophosphate 1-phosphatase activity
BF29_RS00090	COG1217	gtp-binding protein TYPA
BF29_RS00100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF29_RS00105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF29_RS00110	COG4838	Belongs to the UPF0358 family
BF29_RS00115	COG0772	Belongs to the SEDS family
BF29_RS00120	COG1612	heme a metabolic process
BF29_RS00125	COG0109	protoheme IX farnesyltransferase activity
BF29_RS00130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF29_RS00130	COG2010	Cytochrome c
BF29_RS00145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BF29_RS00150	COG3336	cytochrome c oxidase
BF29_RS00160	COG2340	Cysteine-rich secretory protein family
BF29_RS00185	COG3679	Belongs to the UPF0342 family
BF29_RS00190	COG4471	UPF0298 protein
BF29_RS00200	COG0742	ribosomal rna small subunit methyltransferase
BF29_RS00205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BF29_RS00210	COG3314	Sporulation integral membrane protein YlbJ
BF29_RS00215	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF29_RS00220	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF29_RS00230	COG1323	Belongs to the UPF0348 family
BF29_RS00235	COG1399	metal-binding, possibly nucleic acid-binding protein
BF29_RS00240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BF29_RS00250	COG0454	-acetyltransferase
BF29_RS00255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF29_RS00260	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BF29_RS00265	COG2001	Belongs to the MraZ family
BF29_RS00270	COG0275	rRNA processing
BF29_RS00275	COG4839	cell division protein FtsL
BF29_RS00280	COG0768	penicillin binding
BF29_RS00285	COG0768	penicillin binding
BF29_RS00300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF29_RS00305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BF29_RS00310	COG0772	Belongs to the SEDS family
BF29_RS00315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF29_RS00320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF29_RS00325	COG0849	cell division
BF29_RS00330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF29_RS00340	COG1191	sigma factor activity
BF29_RS00345	COG1191	sigma factor activity
BF29_RS00350	COG1873	PFAM PRC-barrel domain
BF29_RS00355	COG1388	LysM domain
BF29_RS00355	COG3584	3D domain protein
BF29_RS00365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF29_RS00370	COG1799	cell septum assembly
BF29_RS00375	COG0762	integral membrane protein
BF29_RS00380	COG2302	S4 RNA-binding domain
BF29_RS00385	COG3599	regulation of cell shape
BF29_RS00400	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BF29_RS00405	COG0564	pseudouridine synthase activity
BF29_RS00410	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BF29_RS00415	COG0540	Belongs to the ATCase OTCase family
BF29_RS00420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BF29_RS00435	COG0543	2 iron, 2 sulfur cluster binding
BF29_RS00440	COG0167	dihydroorotate dehydrogenase activity
BF29_RS00450	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BF29_RS00470	COG0235	Class ii aldolase
BF29_RS00475	COG1803	Methylglyoxal synthase
BF29_RS00490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF29_RS00495	COG0477	Major facilitator Superfamily
BF29_RS00500	COG0477	Major facilitator Superfamily
BF29_RS00505	COG1116	anion transmembrane transporter activity
BF29_RS00510	COG0628	permease
BF29_RS00525	COG0385	Bile acid
BF29_RS00535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF29_RS00540	COG1561	YicC-like family, N-terminal region
BF29_RS00545	COG2052	Domain of unknown function (DUF370)
BF29_RS00550	COG0194	GDP metabolic process
BF29_RS00555	COG1758	RNA polymerase activity
BF29_RS00560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF29_RS00565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF29_RS00570	COG0242	peptide deformylase activity
BF29_RS00575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF29_RS00580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF29_RS00580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF29_RS00585	COG0631	protein serine/threonine phosphatase activity
BF29_RS00590	COG2815	serine threonine protein kinase
BF29_RS00590	COG0515	serine threonine protein kinase
BF29_RS00595	COG1162	GTPase activity
BF29_RS00600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF29_RS00605	COG1564	THIamine pyrophosphokinase
BF29_RS00615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BF29_RS00625	COG1302	Protein conserved in bacteria
BF29_RS00630	COG1461	Dihydroxyacetone kinase
BF29_RS00635	COG1760	l-serine dehydratase
BF29_RS00640	COG1760	l-serine dehydratase
BF29_RS00645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF29_RS00650	COG1349	DNA-binding transcription factor activity
BF29_RS00655	COG0416	fatty acid biosynthetic process
BF29_RS00660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF29_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS00675	COG0571	ribonuclease III activity
BF29_RS00680	COG1196	nuclear chromosome segregation
BF29_RS00685	COG0552	protein localization to endoplasmic reticulum
BF29_RS00690	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BF29_RS00695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF29_RS00705	COG1837	Belongs to the UPF0109 family
BF29_RS00715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BF29_RS00720	COG0336	Belongs to the RNA methyltransferase TrmD family
BF29_RS00735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF29_RS00750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF29_RS00755	COG0045	succinate-CoA ligase (ADP-forming) activity
BF29_RS00760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF29_RS00765	COG0758	DNA mediated transformation
BF29_RS00775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF29_RS00785	COG4974	Belongs to the 'phage' integrase family
BF29_RS00790	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BF29_RS00800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BF29_RS00805	COG1815	bacterial-type flagellum-dependent cell motility
BF29_RS00810	COG1558	bacterial-type flagellum-dependent cell motility
BF29_RS00815	COG1677	Flagellar hook-basal body complex protein FliE
BF29_RS00820	COG1766	The M ring may be actively involved in energy transduction
BF29_RS00825	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF29_RS00830	COG1317	bacterial-type flagellum organization
BF29_RS00835	COG1157	protein secretion by the type III secretion system
BF29_RS00840	COG2882	bacterial-type flagellum organization
BF29_RS00855	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BF29_RS00865	COG4786	Flagellar basal body rod
BF29_RS00875	COG1580	Controls the rotational direction of flagella during chemotaxis
BF29_RS00880	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF29_RS00885	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF29_RS00885	COG1776	CheC inhibitor of MCP methylation
BF29_RS00890	COG2201	protein-glutamate methylesterase activity
BF29_RS00895	COG3190	flagellar
BF29_RS00900	COG1338	Plays a role in the flagellum-specific transport system
BF29_RS00905	COG1987	bacterial-type flagellum assembly
BF29_RS00910	COG1684	flagellar biosynthetic protein fliR
BF29_RS00915	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF29_RS00920	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF29_RS00925	COG1419	protein localization to endoplasmic reticulum
BF29_RS00930	COG0455	bacterial-type flagellum organization
BF29_RS00935	COG2201	protein-glutamate methylesterase activity
BF29_RS00940	COG0643	Histidine kinase
BF29_RS00940	COG2198	Histidine kinase
BF29_RS00945	COG0835	chemotaxis
BF29_RS00950	COG1776	CheC inhibitor of MCP methylation
BF29_RS00955	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BF29_RS00960	COG1191	sigma factor activity
BF29_RS00970	COG0052	Belongs to the universal ribosomal protein uS2 family
BF29_RS00975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BF29_RS00980	COG0528	UMP kinase activity
BF29_RS00985	COG0233	cytoplasmic translational termination
BF29_RS00995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF29_RS01000	COG4589	Belongs to the CDS family
BF29_RS01005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF29_RS01010	COG0750	zinc metalloprotease
BF29_RS01015	COG0442	prolyl-tRNA aminoacylation
BF29_RS01020	COG2176	DNA-directed DNA polymerase activity
BF29_RS01025	COG0779	Required for maturation of 30S ribosomal subunits
BF29_RS01030	COG0195	Participates in both transcription termination and antitermination
BF29_RS01035	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF29_RS01040	COG1358	cellular component organization or biogenesis
BF29_RS01050	COG1550	Protein conserved in bacteria
BF29_RS01055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BF29_RS01060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF29_RS01065	COG0196	riboflavin kinase activity
BF29_RS01070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BF29_RS01075	COG1185	polyribonucleotide nucleotidyltransferase activity
BF29_RS01080	COG0726	polysaccharide deacetylase
BF29_RS01085	COG0612	Peptidase, M16
BF29_RS01090	COG1873	PFAM PRC-barrel domain
BF29_RS01095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF29_RS01100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF29_RS01105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF29_RS01115	COG0527	aspartate kinase activity
BF29_RS01125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF29_RS01130	COG0740	serine-type endopeptidase activity
BF29_RS01140	COG4980	gas vesicle protein
BF29_RS01140	COG1674	ftsk spoiiie
BF29_RS01145	COG1744	ABC transporter substrate-binding protein PnrA-like
BF29_RS01150	COG3845	ABC transporter
BF29_RS01155	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF29_RS01160	COG1079	Belongs to the binding-protein-dependent transport system permease family
BF29_RS01165	COG0612	Peptidase, M16
BF29_RS01170	COG0612	Peptidase, M16
BF29_RS01175	COG0300	oxidoreductase activity
BF29_RS01190	COG1426	Protein conserved in bacteria
BF29_RS01195	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF29_RS01200	COG1058	Belongs to the CinA family
BF29_RS01200	COG1546	Belongs to the CinA family
BF29_RS01210	COG1418	mRNA catabolic process
BF29_RS01215	COG1692	metallophosphoesterase
BF29_RS01220	COG2359	stage V sporulation protein S
BF29_RS01225	COG0826	peptidase U32
BF29_RS01230	COG0826	peptidase U32
BF29_RS01235	COG0531	amino acid
BF29_RS01240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF29_RS01245	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF29_RS01255	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BF29_RS01260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BF29_RS01285	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BF29_RS01300	COG0464	growth
BF29_RS01310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF29_RS01315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF29_RS01320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF29_RS01345	COG1321	iron dependent repressor
BF29_RS01350	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BF29_RS01360	COG0488	(ABC) transporter
BF29_RS01365	COG1413	lyase activity
BF29_RS01380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BF29_RS01385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF29_RS01390	COG1272	protein, Hemolysin III
BF29_RS01395	COG2755	lipolytic protein G-D-S-L family
BF29_RS01405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF29_RS01405	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BF29_RS01410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF29_RS01415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF29_RS01425	COG0840	transmembrane signaling receptor activity
BF29_RS01430	COG4479	Belongs to the UPF0346 family
BF29_RS01450	COG1876	peptidase activity
BF29_RS01455	COG0793	Belongs to the peptidase S41A family
BF29_RS01455	COG3409	Peptidoglycan-binding domain 1 protein
BF29_RS01460	COG1846	Transcriptional regulator
BF29_RS01470	COG2340	Cysteine-rich secretory protein family
BF29_RS01475	COG0534	Mate efflux family protein
BF29_RS01490	COG1793	dna ligase
BF29_RS01490	COG3285	dna ligase
BF29_RS01495	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BF29_RS01500	COG0671	phosphoesterase, PA-phosphatase related
BF29_RS01505	COG1368	sulfuric ester hydrolase activity
BF29_RS01510	COG1331	Highly conserved protein containing a thioredoxin domain
BF29_RS01515	COG2814	Major facilitator Superfamily
BF29_RS01530	COG0745	RESPONSE REGULATOR receiver
BF29_RS01535	COG5002	protein histidine kinase activity
BF29_RS01550	COG0567	Dehydrogenase, E1 component
BF29_RS01555	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF29_RS01560	COG1012	belongs to the aldehyde dehydrogenase family
BF29_RS01580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF29_RS01590	COG1054	Belongs to the UPF0176 family
BF29_RS01595	COG2135	peptidase activity
BF29_RS01605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF29_RS01610	COG0516	GMP reductase activity
BF29_RS01610	COG0517	IMP dehydrogenase activity
BF29_RS01620	COG1388	LysM domain
BF29_RS01620	COG3584	3D domain protein
BF29_RS01625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF29_RS01630	COG1113	amino acid transport
BF29_RS01635	COG0598	Magnesium transport protein CorA
BF29_RS01645	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BF29_RS01650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BF29_RS01660	COG0131	Imidazoleglycerol-phosphate dehydratase
BF29_RS01665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BF29_RS01680	COG0140	phosphoribosyl-ATP diphosphatase activity
BF29_RS01680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BF29_RS01690	COG2391	methyltransferase activity
BF29_RS01695	COG2962	Rard protein
BF29_RS01700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF29_RS01705	COG0569	domain protein
BF29_RS01725	COG2807	transmembrane transport
BF29_RS01730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BF29_RS01740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF29_RS01750	COG1278	Cold shock
BF29_RS01760	COG0302	gtp cyclohydrolase
BF29_RS01765	COG3634	alkyl hydroperoxide reductase activity
BF29_RS01780	COG0577	efflux transmembrane transporter activity
BF29_RS01785	COG1136	(ABC) transporter
BF29_RS01790	COG0642	Histidine kinase
BF29_RS01795	COG0745	RESPONSE REGULATOR receiver
BF29_RS01800	COG1113	amino acid transport
BF29_RS01810	COG0477	Major facilitator Superfamily
BF29_RS01820	COG1132	(ABC) transporter
BF29_RS01825	COG1132	(ABC) transporter
BF29_RS01835	COG1380	Effector of murein hydrolase LrgA
BF29_RS01840	COG1346	cytolysis
BF29_RS01845	COG0318	PFAM AMP-dependent synthetase and ligase
BF29_RS01865	COG2309	aminopeptidase activity
BF29_RS01875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF29_RS01890	COG0824	Thioesterase
BF29_RS01900	COG4841	protein insertion into membrane
BF29_RS01905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF29_RS01910	COG1832	CoA-binding protein
BF29_RS01915	COG0187	DNA topoisomerase II activity
BF29_RS01920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF29_RS01935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BF29_RS01940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BF29_RS01940	COG0574	Belongs to the PEP-utilizing enzyme family
BF29_RS01960	COG2070	2-Nitropropane dioxygenase
BF29_RS01965	COG0681	Belongs to the peptidase S26 family
BF29_RS01985	COG0456	acetyltransferase
BF29_RS01995	COG0456	acetyltransferase
BF29_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS02010	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BF29_RS02015	COG0351	phosphomethylpyrimidine kinase
BF29_RS02020	COG0352	thiamine-phosphate diphosphorylase activity
BF29_RS02030	COG2258	MOSC domain
BF29_RS02080	COG1309	transcriptional regulator
BF29_RS02095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF29_RS02100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF29_RS02120	COG2045	Belongs to the ComB family
BF29_RS02125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BF29_RS02130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF29_RS02150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF29_RS02155	COG0697	spore germination
BF29_RS02160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF29_RS02165	COG0022	dehydrogenase e1 component
BF29_RS02170	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF29_RS02175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF29_RS02180	COG3284	Transcriptional regulator
BF29_RS02185	COG3264	Mechanosensitive ion channel
BF29_RS02185	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BF29_RS02195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF29_RS02200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BF29_RS02215	COG0183	Belongs to the thiolase family
BF29_RS02220	COG0318	PFAM AMP-dependent synthetase and ligase
BF29_RS02230	COG0561	phosphatase activity
BF29_RS02255	COG2322	membrane
BF29_RS02270	COG0039	L-malate dehydrogenase activity
BF29_RS02275	COG0475	glutathione-regulated potassium exporter activity
BF29_RS02275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF29_RS02295	COG0589	response to stress
BF29_RS02310	COG0730	response to heat
BF29_RS02315	COG0583	DNA-binding transcription factor activity
BF29_RS02320	COG2801	Transposase and inactivated derivatives
BF29_RS02325	COG2963	transposase activity
BF29_RS02355	COG0640	Transcriptional regulator
BF29_RS02360	COG0798	PFAM Bile acid sodium symporter
BF29_RS02365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF29_RS02395	COG0003	Pfam Anion-transporting ATPase
BF29_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS02405	COG2223	nitrite transmembrane transporter activity
BF29_RS02410	COG3773	Cell wall hydrolase
BF29_RS02415	COG0708	Exodeoxyribonuclease III
BF29_RS02420	COG2084	Dehydrogenase
BF29_RS02425	COG0297	glycogen (starch) synthase activity
BF29_RS02430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF29_RS02435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF29_RS02440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BF29_RS02460	COG1247	-acetyltransferase
BF29_RS02465	COG0494	nUDIX hydrolase
BF29_RS02470	COG1914	H( )-stimulated, divalent metal cation uptake system
BF29_RS02475	COG0783	Belongs to the Dps family
BF29_RS02485	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF29_RS02490	COG1131	(ABC) transporter
BF29_RS02520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF29_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS02545	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BF29_RS02550	COG0709	Synthesizes selenophosphate from selenide and ATP
BF29_RS02560	COG0701	Predicted permease
BF29_RS02565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BF29_RS02570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF29_RS02585	COG1252	NADH dehydrogenase
BF29_RS02590	COG2404	hydrolase activity, acting on ester bonds
BF29_RS02605	COG4990	cell redox homeostasis
BF29_RS02610	COG0789	Transcriptional regulator
BF29_RS02640	COG0436	Aminotransferase
BF29_RS02645	COG0165	Argininosuccinate lyase
BF29_RS02650	COG0137	argininosuccinate synthase activity
BF29_RS02655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BF29_RS02660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BF29_RS02665	COG0505	Belongs to the CarA family
BF29_RS02670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF29_RS02675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BF29_RS02680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF29_RS02685	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BF29_RS02720	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF29_RS02725	COG2027	D-alanyl-D-alanine carboxypeptidase
BF29_RS02730	COG0204	Acyl-transferase
BF29_RS02740	COG4846	Membrane protein involved in cytochrome C biogenesis
BF29_RS02745	COG2201	protein-glutamate methylesterase activity
BF29_RS02750	COG0785	Cytochrome C biogenesis protein
BF29_RS02755	COG3763	UPF0154 protein
BF29_RS02770	COG4224	UPF0291 protein
BF29_RS02775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF29_RS02785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BF29_RS02790	COG0174	glutamine synthetase
BF29_RS02795	COG0789	Transcriptional regulator
BF29_RS02800	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF29_RS02815	COG2233	PERMEase
BF29_RS02825	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF29_RS02830	COG0116	Belongs to the methyltransferase superfamily
BF29_RS02840	COG4474	Belongs to the UPF0398 family
BF29_RS02850	COG3359	exonuclease
BF29_RS02855	COG1111	helicase
BF29_RS02855	COG1205	dead DEAH box helicase
BF29_RS02860	COG0071	Belongs to the small heat shock protein (HSP20) family
BF29_RS02885	COG3331	DNA recombination
BF29_RS02890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF29_RS02890	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF29_RS02895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF29_RS02900	COG3935	DnaD domain protein
BF29_RS02905	COG0017	Asparaginyl-tRNA synthetase
BF29_RS02920	COG1199	ATP-dependent helicase activity
BF29_RS02920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF29_RS02925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BF29_RS02930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BF29_RS02950	COG0438	transferase activity, transferring glycosyl groups
BF29_RS02955	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF29_RS02960	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BF29_RS02965	COG1694	Mazg nucleotide pyrophosphohydrolase
BF29_RS02970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF29_RS02980	COG2738	Putative neutral zinc metallopeptidase
BF29_RS02990	COG4347	Protein of unknown function (DUF1405)
BF29_RS03000	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF29_RS03015	COG5582	Belongs to the UPF0302 family
BF29_RS03020	COG0457	Tetratricopeptide repeat
BF29_RS03025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BF29_RS03030	COG0287	Prephenate dehydrogenase
BF29_RS03035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF29_RS03040	COG4401	Chorismate mutase type I
BF29_RS03045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BF29_RS03050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF29_RS03055	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF29_RS03060	COG0105	UTP biosynthetic process
BF29_RS03065	COG0142	geranyltranstransferase activity
BF29_RS03070	COG2226	methyltransferase
BF29_RS03075	COG0142	geranyltranstransferase activity
BF29_RS03085	COG0776	regulation of translation
BF29_RS03090	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF29_RS03110	COG1160	GTP binding
BF29_RS03120	COG0539	negative regulation of cytoplasmic translation
BF29_RS03125	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BF29_RS03135	COG2959	enzyme of heme biosynthesis
BF29_RS03140	COG3773	Cell wall hydrolase
BF29_RS03140	COG3409	Peptidoglycan-binding domain 1 protein
BF29_RS03145	COG2339	peptidase activity
BF29_RS03150	COG0492	ferredoxin-NADP+ reductase activity
BF29_RS03155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF29_RS03165	COG1408	metallophosphoesterase
BF29_RS03180	COG3546	catalase activity
BF29_RS03195	COG1266	CAAX protease self-immunity
BF29_RS03200	COG0514	ATP-dependent DNA helicase (RecQ)
BF29_RS03215	COG1141	Ferredoxin
BF29_RS03220	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF29_RS03225	COG1196	nuclear chromosome segregation
BF29_RS03225	COG0741	lytic transglycosylase activity
BF29_RS03225	COG0739	heme binding
BF29_RS03230	COG5002	protein histidine kinase activity
BF29_RS03235	COG0745	RESPONSE REGULATOR receiver
BF29_RS03240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF29_RS03245	COG1333	cytochrome c biogenesis protein
BF29_RS03250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS03255	COG1187	pseudouridine synthase activity
BF29_RS03260	COG0700	Nucleoside recognition
BF29_RS03265	COG2715	membrane protein required for spore maturation
BF29_RS03270	COG1686	Belongs to the peptidase S11 family
BF29_RS03275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BF29_RS03295	COG0697	spore germination
BF29_RS03315	COG1191	sigma factor activity
BF29_RS03330	COG1686	Belongs to the peptidase S11 family
BF29_RS03335	COG4974	Belongs to the 'phage' integrase family
BF29_RS03345	COG0735	belongs to the Fur family
BF29_RS03350	COG1300	Membrane
BF29_RS03355	COG1379	DNA repair
BF29_RS03370	COG0667	Aldo Keto reductase
BF29_RS03380	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BF29_RS03385	COG3853	Toxic anion resistance protein (TelA)
BF29_RS03390	COG1073	alpha beta
BF29_RS03395	COG3858	chitin binding
BF29_RS03395	COG1388	LysM domain
BF29_RS03405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF29_RS03410	COG0300	oxidoreductase activity
BF29_RS03415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF29_RS03425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF29_RS03440	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF29_RS03450	COG1376	ErfK ybiS ycfS ynhG family protein
BF29_RS03460	COG1105	Belongs to the carbohydrate kinase PfkB family
BF29_RS03465	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF29_RS03470	COG0022	dehydrogenase e1 component
BF29_RS03475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF29_RS03480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF29_RS03490	COG3829	transcription factor binding
BF29_RS03490	COG3290	protein histidine kinase activity
BF29_RS03505	COG0584	glycerophosphoryl diester phosphodiesterase
BF29_RS03510	COG0745	RESPONSE REGULATOR receiver
BF29_RS03515	COG0750	zinc metalloprotease
BF29_RS03520	COG0497	DNA recombination
BF29_RS03530	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF29_RS03535	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BF29_RS03550	COG1570	exodeoxyribonuclease VII activity
BF29_RS03555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BF29_RS03565	COG1302	Protein conserved in bacteria
BF29_RS03570	COG0439	Biotin carboxylase
BF29_RS03575	COG0511	ligase activity, forming carbon-carbon bonds
BF29_RS03615	COG3854	ATPases associated with a variety of cellular activities
BF29_RS03620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BF29_RS03625	COG0006	proline dipeptidase activity
BF29_RS03630	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BF29_RS03640	COG3872	metal-dependent enzyme
BF29_RS03650	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF29_RS03660	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF29_RS03665	COG0183	Belongs to the thiolase family
BF29_RS03670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF29_RS03675	COG0095	Lipoate-protein ligase
BF29_RS03680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF29_RS03685	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BF29_RS03695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BF29_RS03700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF29_RS03710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BF29_RS03735	COG4537	Required for transformation and DNA binding
BF29_RS03740	COG1459	type II secretion system
BF29_RS03745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF29_RS03760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF29_RS03770	COG1940	carbohydrate kinase activity
BF29_RS03775	COG4483	Protein conserved in bacteria
BF29_RS03780	COG0457	Tetratricopeptide repeat
BF29_RS03780	COG0705	Rhomboid family
BF29_RS03785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF29_RS03795	COG0768	penicillin binding
BF29_RS03800	COG0477	Major facilitator Superfamily
BF29_RS03805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF29_RS03815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BF29_RS03820	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BF29_RS03825	COG0735	belongs to the Fur family
BF29_RS03830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF29_RS03835	COG1121	(ABC) transporter
BF29_RS03845	COG3883	PFAM NLP P60 protein
BF29_RS03845	COG0791	NLP P60 protein
BF29_RS03850	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BF29_RS03855	COG0513	Belongs to the DEAD box helicase family
BF29_RS03865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BF29_RS03870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF29_RS03875	COG2384	SAM-dependent methyltransferase
BF29_RS03880	COG2010	Cytochrome c
BF29_RS03890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF29_RS03895	COG0358	DNA primase activity
BF29_RS03905	COG0517	IMP dehydrogenase activity
BF29_RS03915	COG1381	Involved in DNA repair and RecF pathway recombination
BF29_RS03920	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF29_RS03925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF29_RS03930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BF29_RS03940	COG1702	phosphate starvation-inducible protein PhoH
BF29_RS03960	COG1610	YqeY-like protein
BF29_RS03970	COG1254	Belongs to the acylphosphatase family
BF29_RS03975	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF29_RS03980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF29_RS03985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF29_RS03990	COG2264	protein methyltransferase activity
BF29_RS04000	COG0443	Heat shock 70 kDa protein
BF29_RS04005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF29_RS04015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF29_RS04020	COG0481	GTPase activity
BF29_RS04025	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF29_RS04030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BF29_RS04035	COG0268	Binds directly to 16S ribosomal RNA
BF29_RS04040	COG1466	dna polymerase III delta subunit
BF29_RS04050	COG2333	competence protein COMEC
BF29_RS04050	COG0658	competence protein
BF29_RS04055	COG2131	deaminase
BF29_RS04060	COG1555	photosystem II stabilization
BF29_RS04060	COG1596	polysaccharide export
BF29_RS04065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF29_RS04070	COG2226	methyltransferase
BF29_RS04075	COG0799	negative regulation of ribosome biogenesis
BF29_RS04080	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF29_RS04085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BF29_RS04090	COG1534	Rna-binding protein
BF29_RS04100	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF29_RS04105	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF29_RS04110	COG0247	lactate metabolic process
BF29_RS04115	COG0277	FAD linked oxidase domain protein
BF29_RS04120	COG3835	regulator
BF29_RS04125	COG2132	Multicopper oxidase
BF29_RS04130	COG0071	Belongs to the small heat shock protein (HSP20) family
BF29_RS04140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS04150	COG1704	LemA family
BF29_RS04180	COG1183	phosphatidylcholine synthase activity
BF29_RS04190	COG3634	alkyl hydroperoxide reductase activity
BF29_RS04195	COG0450	alkyl hydroperoxide reductase
BF29_RS04210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF29_RS04225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BF29_RS04230	COG0572	uridine kinase
BF29_RS04235	COG4122	O-methyltransferase activity
BF29_RS04240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF29_RS04245	COG3906	Belongs to the UPF0473 family
BF29_RS04250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BF29_RS04255	COG4472	Bacterial protein of unknown function (DUF965)
BF29_RS04260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF29_RS04265	COG0628	permease
BF29_RS04285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF29_RS04290	COG1477	protein flavinylation
BF29_RS04290	COG0457	Tetratricopeptide repeat
BF29_RS04295	COG0482	sulfurtransferase activity
BF29_RS04300	COG1104	cysteine desulfurase activity
BF29_RS04305	COG1959	2 iron, 2 sulfur cluster binding
BF29_RS04320	COG0730	response to heat
BF29_RS04325	COG0425	Belongs to the sulfur carrier protein TusA family
BF29_RS04330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF29_RS04330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF29_RS04335	COG2210	Belongs to the sulfur carrier protein TusA family
BF29_RS04340	COG0425	Belongs to the sulfur carrier protein TusA family
BF29_RS04340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF29_RS04345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF29_RS04350	COG1937	Protein conserved in bacteria
BF29_RS04380	COG0785	Cytochrome C biogenesis protein
BF29_RS04395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS04430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF29_RS04435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF29_RS04440	COG0385	Bile acid
BF29_RS04445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BF29_RS04450	COG0124	histidyl-tRNA synthetase
BF29_RS04455	COG3103	Sh3 type 3 domain protein
BF29_RS04455	COG4991	sh3 domain protein
BF29_RS04455	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF29_RS04460	COG2814	Major facilitator Superfamily
BF29_RS04465	COG1566	PFAM secretion protein HlyD family protein
BF29_RS04470	COG1846	Transcriptional regulator
BF29_RS04475	COG1490	D-aminoacyl-tRNA deacylase activity
BF29_RS04480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF29_RS04485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF29_RS04490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF29_RS04490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF29_RS04495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF29_RS04495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF29_RS04505	COG2244	polysaccharide biosynthetic process
BF29_RS04510	COG2323	membrane
BF29_RS04520	COG1862	Preprotein translocase
BF29_RS04525	COG0343	queuine tRNA-ribosyltransferase activity
BF29_RS04530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BF29_RS04545	COG0632	four-way junction helicase activity
BF29_RS04555	COG0217	transcriptional regulatory protein
BF29_RS04565	COG1388	LysM domain
BF29_RS04570	COG1827	regulation of RNA biosynthetic process
BF29_RS04575	COG0077	Prephenate dehydratase
BF29_RS04580	COG4492	Belongs to the UPF0735 family
BF29_RS04585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF29_RS04590	COG3290	protein histidine kinase activity
BF29_RS04595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BF29_RS04600	COG2868	ribosomal protein
BF29_RS04605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BF29_RS04610	COG1530	ribonuclease E activity
BF29_RS04615	COG1994	Peptidase M50
BF29_RS04625	COG2894	cell division
BF29_RS04630	COG0850	regulation of cytokinetic process
BF29_RS04640	COG1792	Involved in formation and maintenance of cell shape
BF29_RS04645	COG1077	Cell shape determining protein MreB Mrl
BF29_RS04655	COG2003	Belongs to the UPF0758 family
BF29_RS04665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF29_RS04690	COG1459	type II secretion system
BF29_RS04700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF29_RS04740	COG0285	dihydrofolate synthase activity
BF29_RS04745	COG0525	valine-tRNA ligase activity
BF29_RS04755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF29_RS04760	COG1388	LysM domain
BF29_RS04760	COG1388	LysM domain
BF29_RS04765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BF29_RS04770	COG0113	porphobilinogen synthase activity
BF29_RS04780	COG0181	hydroxymethylbilane synthase activity
BF29_RS04785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF29_RS04800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BF29_RS04805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BF29_RS04810	COG1067	ATP-dependent peptidase activity
BF29_RS04810	COG0470	DNA polymerase III
BF29_RS04820	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF29_RS04825	COG0457	Tetratricopeptide repeat
BF29_RS04825	COG1477	protein flavinylation
BF29_RS04845	COG0622	Phosphoesterase
BF29_RS04850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BF29_RS04855	COG5401	PFAM Sporulation and spore germination
BF29_RS04870	COG1846	Transcriptional regulator
BF29_RS04885	COG2801	Transposase and inactivated derivatives
BF29_RS04890	COG2963	transposase activity
BF29_RS04905	COG2197	response regulator
BF29_RS04915	COG0824	Thioesterase
BF29_RS04920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF29_RS04925	COG1053	succinate dehydrogenase
BF29_RS04930	COG2009	succinate dehydrogenase
BF29_RS04935	COG1719	4-vinyl reductase, 4VR
BF29_RS04950	COG0322	excinuclease ABC activity
BF29_RS04955	COG3118	belongs to the thioredoxin family
BF29_RS04960	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF29_RS04965	COG2086	electron transfer activity
BF29_RS04970	COG1024	Enoyl-CoA hydratase
BF29_RS04975	COG1309	transcriptional regulator
BF29_RS04980	COG0318	PFAM AMP-dependent synthetase and ligase
BF29_RS04985	COG1193	negative regulation of DNA recombination
BF29_RS04990	COG1796	DNA polymerase
BF29_RS04990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF29_RS04995	COG1286	toxin biosynthetic process
BF29_RS05000	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BF29_RS05020	COG0072	phenylalanine-tRNA ligase activity
BF29_RS05020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF29_RS05025	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BF29_RS05030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF29_RS05055	COG2963	transposase activity
BF29_RS05060	COG2801	Transposase and inactivated derivatives
BF29_RS05070	COG1695	Transcriptional regulator
BF29_RS05090	COG0431	NADPH-dependent FMN reductase
BF29_RS05095	COG1363	Peptidase, m42
BF29_RS05105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BF29_RS05115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF29_RS05125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF29_RS05135	COG1484	DNA-dependent DNA replication
BF29_RS05140	COG3611	Membrane attachment protein
BF29_RS05145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BF29_RS05155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF29_RS05160	COG0237	dephospho-CoA kinase activity
BF29_RS05165	COG1971	Probably functions as a manganese efflux pump
BF29_RS05170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BF29_RS05175	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF29_RS05175	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF29_RS05185	COG0039	L-malate dehydrogenase activity
BF29_RS05190	COG0538	isocitrate dehydrogenase activity
BF29_RS05195	COG0372	Belongs to the citrate synthase family
BF29_RS05200	COG2707	UPF0756 membrane protein
BF29_RS05205	COG0628	permease
BF29_RS05215	COG0205	6-phosphofructokinase activity
BF29_RS05220	COG0825	malonyl-CoA metabolic process
BF29_RS05225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BF29_RS05230	COG0281	malic enzyme
BF29_RS05235	COG0587	DNA-directed DNA polymerase activity
BF29_RS05250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF29_RS05260	COG4109	DRTGG domain
BF29_RS05265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF29_RS05270	COG0006	proline dipeptidase activity
BF29_RS05280	COG0589	response to stress
BF29_RS05290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF29_RS05295	COG0827	DNA restriction-modification system
BF29_RS05300	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF29_RS05305	COG3874	Sporulation protein YtfJ
BF29_RS05315	COG1714	RDD family
BF29_RS05320	COG0616	signal peptide processing
BF29_RS05325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF29_RS05335	COG0301	tRNA thio-modification
BF29_RS05340	COG1104	cysteine desulfurase activity
BF29_RS05350	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BF29_RS05355	COG1309	transcriptional regulator
BF29_RS05360	COG1956	GAF domain-containing protein
BF29_RS05365	COG2199	diguanylate cyclase activity
BF29_RS05365	COG2203	Gaf domain
BF29_RS05370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BF29_RS05385	COG0506	proline dehydrogenase activity
BF29_RS05390	COG1012	belongs to the aldehyde dehydrogenase family
BF29_RS05395	COG3829	transcription factor binding
BF29_RS05395	COG3290	protein histidine kinase activity
BF29_RS05410	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF29_RS05415	COG3383	formate dehydrogenase (NAD+) activity
BF29_RS05420	COG2427	Protein of unknown function (DUF1641)
BF29_RS05425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF29_RS05430	COG0315	cyclic pyranopterin monophosphate synthase activity
BF29_RS05435	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BF29_RS05440	COG0314	molybdopterin synthase activity
BF29_RS05445	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF29_RS05450	COG0303	'Molybdopterin
BF29_RS05465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF29_RS05475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BF29_RS05480	COG4149	molybdate abc transporter
BF29_RS05490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF29_RS05495	COG0454	-acetyltransferase
BF29_RS05500	COG0517	IMP dehydrogenase activity
BF29_RS05505	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF29_RS05515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF29_RS05515	COG1605	Chorismate mutase
BF29_RS05520	COG4980	gas vesicle protein
BF29_RS05530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BF29_RS05535	COG1674	ftsk spoiiie
BF29_RS05545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF29_RS05550	COG4848	Belongs to the UPF0354 family
BF29_RS05555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS05560	COG2208	phosphoserine phosphatase activity
BF29_RS05565	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF29_RS05570	COG5002	protein histidine kinase activity
BF29_RS05570	COG0784	Response regulator, receiver
BF29_RS05580	COG5584	Small secreted protein
BF29_RS05585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF29_RS05595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BF29_RS05605	COG0510	thiamine kinase activity
BF29_RS05630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF29_RS05640	COG1349	DNA-binding transcription factor activity
BF29_RS05645	COG2244	polysaccharide biosynthetic process
BF29_RS05665	COG0495	leucyl-tRNA aminoacylation
BF29_RS05670	COG2814	Major facilitator Superfamily
BF29_RS05685	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF29_RS05695	COG2267	carboxylic ester hydrolase activity
BF29_RS05700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF29_RS05705	COG0367	asparagine synthase
BF29_RS05710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BF29_RS05730	COG1506	peptidase
BF29_RS05735	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF29_RS05745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF29_RS05750	COG1116	anion transmembrane transporter activity
BF29_RS05755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF29_RS05770	COG0783	Belongs to the Dps family
BF29_RS05775	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BF29_RS05780	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF29_RS05785	COG4948	Mandelate Racemase Muconate Lactonizing
BF29_RS05790	COG0318	PFAM AMP-dependent synthetase and ligase
BF29_RS05795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF29_RS05800	COG0596	Alpha beta hydrolase
BF29_RS05805	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF29_RS05810	COG1169	isochorismate synthase
BF29_RS05815	COG1575	Belongs to the MenA family. Type 1 subfamily
BF29_RS05965	COG1285	pathogenesis
BF29_RS05980	COG2217	Heavy metal translocating P-type atpase
BF29_RS05985	COG2608	mercury ion transmembrane transporter activity
BF29_RS05995	COG1522	sequence-specific DNA binding
BF29_RS06020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF29_RS06050	COG5002	protein histidine kinase activity
BF29_RS06055	COG0745	RESPONSE REGULATOR receiver
BF29_RS06060	COG1388	LysM domain
BF29_RS06070	COG0726	polysaccharide deacetylase
BF29_RS06090	COG0038	chloride channel
BF29_RS06095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF29_RS06100	COG1937	Protein conserved in bacteria
BF29_RS06110	COG1525	nuclease
BF29_RS06115	COG2190	(PTS) system
BF29_RS06125	COG2963	transposase activity
BF29_RS06130	COG2801	Transposase and inactivated derivatives
BF29_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS06155	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF29_RS06170	COG1012	belongs to the aldehyde dehydrogenase family
BF29_RS06190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF29_RS06200	COG2155	Conserved Protein
BF29_RS06210	COG1098	S1 RNA binding domain
BF29_RS06225	COG1902	pentaerythritol trinitrate reductase activity
BF29_RS06230	COG0656	L-ascorbic acid biosynthetic process
BF29_RS06250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF29_RS06295	COG2814	Major facilitator Superfamily
BF29_RS06300	COG2050	protein possibly involved in aromatic compounds catabolism
BF29_RS06315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BF29_RS06325	COG0697	spore germination
BF29_RS06335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BF29_RS06340	COG3584	3D domain protein
BF29_RS06350	COG1252	NADH dehydrogenase
BF29_RS06355	COG0492	ferredoxin-NADP+ reductase activity
BF29_RS06370	COG0726	polysaccharide deacetylase
BF29_RS06395	COG0316	Belongs to the HesB IscA family
BF29_RS06400	COG4837	Protein of unknown function (DUF1462)
BF29_RS06405	COG2963	transposase activity
BF29_RS06410	COG2801	Transposase and inactivated derivatives
BF29_RS06420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF29_RS06425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF29_RS06430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF29_RS06435	COG0647	UMP catabolic process
BF29_RS06440	COG2445	Protein of unknown function DUF86
BF29_RS06445	COG4470	Protein conserved in bacteria
BF29_RS06450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BF29_RS06455	COG0739	heme binding
BF29_RS06465	COG3377	Domain of unknown function (DUF1805)
BF29_RS06470	COG0737	Belongs to the 5'-nucleotidase family
BF29_RS06475	COG0719	Fe-S assembly protein
BF29_RS06480	COG0822	iron-sulfur transferase activity
BF29_RS06485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF29_RS06490	COG0719	Fe-S assembly protein
BF29_RS06495	COG0396	ATPase activity
BF29_RS06510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS06515	COG0509	glycine decarboxylation via glycine cleavage system
BF29_RS06520	COG1393	Belongs to the ArsC family
BF29_RS06525	COG1960	acyl-CoA dehydrogenase activity
BF29_RS06530	COG0183	Belongs to the thiolase family
BF29_RS06535	COG1024	Enoyl-CoA hydratase
BF29_RS06535	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF29_RS06545	COG5577	PFAM Coat F domain
BF29_RS06550	COG0772	Belongs to the SEDS family
BF29_RS06555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS06575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF29_RS06585	COG0753	catalase activity
BF29_RS06590	COG0671	phosphoesterase, PA-phosphatase related
BF29_RS06600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF29_RS06620	COG1595	DNA-templated transcription, initiation
BF29_RS06630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF29_RS06650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF29_RS06660	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BF29_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS06670	COG2211	Major facilitator Superfamily
BF29_RS06675	COG1904	glucuronate isomerase
BF29_RS06680	COG2721	sulfolactate sulfo-lyase activity
BF29_RS06685	COG0246	Mannitol dehydrogenase
BF29_RS06695	COG0800	Aldolase
BF29_RS06715	COG0488	(ABC) transporter
BF29_RS06730	COG2963	transposase activity
BF29_RS06735	COG2801	Transposase and inactivated derivatives
BF29_RS06775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BF29_RS06780	COG0557	exoribonuclease II activity
BF29_RS06790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF29_RS06795	COG0148	phosphopyruvate hydratase activity
BF29_RS06800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF29_RS06810	COG0126	phosphoglycerate kinase activity
BF29_RS06830	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF29_RS06850	COG3383	formate dehydrogenase (NAD+) activity
BF29_RS06865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF29_RS06875	COG4608	Belongs to the ABC transporter superfamily
BF29_RS06880	COG0791	NLP P60 protein
BF29_RS06885	COG4166	transmembrane transport
BF29_RS06890	COG0444	Belongs to the ABC transporter superfamily
BF29_RS06895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF29_RS06900	COG0601	transmembrane transport
BF29_RS06905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BF29_RS06915	COG0598	Magnesium transport protein CorA
BF29_RS06930	COG2719	SpoVR family
BF29_RS06935	COG3594	Acyltransferase
BF29_RS06965	COG1392	Phosphate transport regulator
BF29_RS06970	COG0306	phosphate transporter
BF29_RS06985	COG2718	Belongs to the UPF0229 family
BF29_RS06990	COG2766	serine protein kinase
BF29_RS06995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF29_RS07010	COG2095	MarC family integral membrane protein
BF29_RS07020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF29_RS07025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF29_RS07030	COG0765	amino acid transport
BF29_RS07040	COG2116	formate transmembrane transporter activity
BF29_RS07050	COG1882	Formate acetyltransferase
BF29_RS07055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF29_RS07065	COG0431	NADPH-dependent FMN reductase
BF29_RS07080	COG1131	(ABC) transporter
BF29_RS07105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF29_RS07220	COG3527	Alpha-acetolactate decarboxylase
BF29_RS07225	COG0028	Belongs to the TPP enzyme family
BF29_RS07230	COG0583	DNA-binding transcription factor activity
BF29_RS07235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF29_RS07240	COG0735	belongs to the Fur family
BF29_RS07255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BF29_RS07265	COG4129	membrane
BF29_RS07270	COG1737	Transcriptional regulator
BF29_RS07275	COG1263	PTS System
BF29_RS07275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF29_RS07280	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BF29_RS07295	COG1132	(ABC) transporter
BF29_RS07300	COG3557	Belongs to the UPF0374 family
BF29_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS07320	COG0583	DNA-binding transcription factor activity
BF29_RS07325	COG0069	glutamate synthase activity
BF29_RS07325	COG0067	glutamate synthase
BF29_RS07325	COG0070	glutamate synthase
BF29_RS07330	COG0493	'glutamate synthase
BF29_RS07340	COG1194	a g-specific adenine glycosylase
BF29_RS07345	COG1988	membrane-bound metal-dependent
BF29_RS07360	COG2137	regulation of response to DNA damage stimulus
BF29_RS07370	COG0159	tryptophan synthase activity
BF29_RS07375	COG0133	tryptophan synthase activity
BF29_RS07380	COG0134	indole-3-glycerol-phosphate synthase activity
BF29_RS07385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF29_RS07390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF29_RS07390	COG0512	Glutamine amidotransferase of anthranilate synthase
BF29_RS07405	COG1136	(ABC) transporter
BF29_RS07405	COG0577	efflux transmembrane transporter activity
BF29_RS07415	COG0058	SHG alpha-glucan phosphorylase activity
BF29_RS07425	COG0840	transmembrane signaling receptor activity
BF29_RS07430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF29_RS07435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF29_RS07440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF29_RS07455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF29_RS07460	COG0066	3-isopropylmalate dehydratase activity
BF29_RS07465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BF29_RS07475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF29_RS07480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF29_RS07485	COG0440	acetolactate synthase activity
BF29_RS07490	COG0028	Belongs to the TPP enzyme family
BF29_RS07495	COG0129	dihydroxy-acid dehydratase activity
BF29_RS07505	COG1114	Component of the transport system for branched-chain amino acids
BF29_RS07510	COG1366	Belongs to the anti-sigma-factor antagonist family
BF29_RS07520	COG2124	cytochrome p450
BF29_RS07525	COG0670	Belongs to the BI1 family
BF29_RS07530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BF29_RS07535	COG2223	nitrite transmembrane transporter activity
BF29_RS07545	COG3279	Response regulator of the LytR AlgR family
BF29_RS07550	COG3275	phosphorelay sensor kinase activity
BF29_RS07555	COG0252	asparaginase activity
BF29_RS07560	COG2132	Multicopper oxidase
BF29_RS07565	COG1511	domain protein
BF29_RS07590	COG3739	integral membrane protein
BF29_RS07595	COG3655	Transcriptional regulator
BF29_RS07610	COG1823	symporter activity
BF29_RS07615	COG2839	Protein conserved in bacteria
BF29_RS07635	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BF29_RS07640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF29_RS07645	COG1279	arginine transmembrane transporter activity
BF29_RS07655	COG1132	(ABC) transporter
BF29_RS07665	COG1132	(ABC) transporter
BF29_RS07670	COG1846	Transcriptional regulator
BF29_RS07675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF29_RS07680	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF29_RS07700	COG0387	Pfam Sodium calcium exchanger
BF29_RS07705	COG0477	Major facilitator Superfamily
BF29_RS07710	COG1295	ribonuclease BN
BF29_RS07715	COG4840	Belongs to the UPF0435 family
BF29_RS07720	COG0024	Methionine aminopeptidase
BF29_RS07725	COG0693	protein deglycase activity
BF29_RS07735	COG1360	Flagellar Motor Protein
BF29_RS07740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF29_RS07750	COG3189	MarR family transcriptional regulator
BF29_RS07760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF29_RS07765	COG1607	acyl-coa hydrolase
BF29_RS07770	COG1077	Cell shape determining protein MreB Mrl
BF29_RS07775	COG2268	Band 7 protein
BF29_RS07780	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF29_RS07785	COG0626	cystathionine gamma-synthase activity
BF29_RS07790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF29_RS07795	COG1854	S-ribosylhomocysteine lyase activity
BF29_RS07800	COG2226	methyltransferase
BF29_RS07805	COG0288	reversible hydration of carbon dioxide
BF29_RS07825	COG2197	response regulator
BF29_RS07845	COG4086	secreted protein
BF29_RS07850	COG1737	Transcriptional regulator
BF29_RS07855	COG0737	Belongs to the 5'-nucleotidase family
BF29_RS07875	COG3620	sequence-specific DNA binding
BF29_RS07885	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BF29_RS07890	COG1518	maintenance of DNA repeat elements
BF29_RS07950	COG2801	Transposase and inactivated derivatives
BF29_RS07955	COG2963	transposase activity
BF29_RS07990	COG1304	FMN binding
BF29_RS07995	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BF29_RS08000	COG0166	Belongs to the GPI family
BF29_RS08005	COG0025	NhaP-type Na H and K H
BF29_RS08010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF29_RS08010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF29_RS08010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF29_RS08015	COG1349	DNA-binding transcription factor activity
BF29_RS08020	COG0371	Dehydrogenase
BF29_RS08025	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF29_RS08035	COG0561	phosphatase activity
BF29_RS08050	COG2814	Major facilitator Superfamily
BF29_RS08055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BF29_RS08085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF29_RS08090	COG0531	amino acid
BF29_RS08095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF29_RS08100	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BF29_RS08105	COG1461	Dihydroxyacetone kinase
BF29_RS08110	COG2376	Dihydroxyacetone kinase
BF29_RS08180	COG0778	Nitroreductase
BF29_RS08185	COG1113	amino acid transport
BF29_RS08195	COG0730	response to heat
BF29_RS08200	COG2233	PERMEase
BF29_RS08205	COG0210	DNA helicase
BF29_RS08210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BF29_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS08225	COG1683	Conserved Protein
BF29_RS08255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF29_RS08260	COG3829	transcription factor binding
BF29_RS08280	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BF29_RS08290	COG0833	amino acid
BF29_RS08315	COG3588	fructose-bisphosphate aldolase
BF29_RS08340	COG0494	nUDIX hydrolase
BF29_RS08345	COG1715	Restriction endonuclease
BF29_RS08350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BF29_RS08375	COG1280	lysine exporter protein (LysE YggA)
BF29_RS08380	COG0386	Belongs to the glutathione peroxidase family
BF29_RS08385	COG2190	(PTS) system
BF29_RS08400	COG0582	viral genome integration into host DNA
BF29_RS08415	COG2963	transposase activity
BF29_RS08420	COG2801	Transposase and inactivated derivatives
BF29_RS08440	COG1301	dicarboxylic acid transport
BF29_RS08455	COG1328	CTP reductase activity
BF29_RS08465	COG1063	alcohol dehydrogenase
BF29_RS08470	COG1929	Belongs to the glycerate kinase type-1 family
BF29_RS08480	COG2801	Transposase and inactivated derivatives
BF29_RS08485	COG2963	transposase activity
BF29_RS08495	COG4549	nuclear export factor GLE1
BF29_RS08500	COG1276	copper resistance
BF29_RS08500	COG2372	response to copper ion
BF29_RS08520	COG5002	protein histidine kinase activity
BF29_RS08525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF29_RS08530	COG1278	Cold shock
BF29_RS08545	COG1472	Belongs to the glycosyl hydrolase 3 family
BF29_RS08555	COG3876	Protein conserved in bacteria
BF29_RS08560	COG1132	(ABC) transporter
BF29_RS08565	COG1132	(ABC) transporter
BF29_RS08575	COG0791	NLP P60 protein
BF29_RS08575	COG1388	LysM domain
BF29_RS08610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF29_RS08610	COG3153	acetyltransferase
BF29_RS08615	COG5583	Uncharacterized small protein (DUF2292)
BF29_RS08620	COG0431	NADPH-dependent FMN reductase
BF29_RS08630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF29_RS08635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF29_RS08640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF29_RS08650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BF29_RS08660	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BF29_RS08665	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF29_RS08675	COG2390	Transcriptional regulator
BF29_RS08685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF29_RS08700	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BF29_RS08715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BF29_RS08720	COG1984	allophanate hydrolase subunit 2
BF29_RS08725	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF29_RS08730	COG2814	Major facilitator Superfamily
BF29_RS08735	COG1764	response to oxidative stress
BF29_RS08740	COG1126	abc transporter atp-binding protein
BF29_RS08745	COG0765	amino acid transport
BF29_RS08750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF29_RS08755	COG1473	amidohydrolase
BF29_RS08760	COG0326	Molecular chaperone. Has ATPase activity
BF29_RS08785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF29_RS08795	COG1064	alcohol dehydrogenase
BF29_RS08865	COG1401	restriction endodeoxyribonuclease activity
BF29_RS08960	COG2963	transposase activity
BF29_RS09000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF29_RS09005	COG1597	lipid kinase activity
BF29_RS09025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BF29_RS09030	COG0154	amidase activity
BF29_RS09035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BF29_RS09040	COG2224	Isocitrate lyase
BF29_RS09045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF29_RS09050	COG4851	CamS sex pheromone cAM373 precursor
BF29_RS09060	COG0210	DNA helicase
BF29_RS09065	COG3344	reverse transcriptase
BF29_RS09070	COG0210	DNA helicase
BF29_RS09075	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BF29_RS09085	COG4496	protein, YerC YecD
BF29_RS09090	COG1470	cell adhesion involved in biofilm formation
BF29_RS09105	COG0151	Belongs to the GarS family
BF29_RS09115	COG0138	bifunctional purine biosynthesis protein purh
BF29_RS09120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF29_RS09125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BF29_RS09130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF29_RS09135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF29_RS09140	COG0047	phosphoribosylformylglycinamidine synthase activity
BF29_RS09145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF29_RS09155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF29_RS09160	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF29_RS09165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF29_RS09175	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BF29_RS09180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF29_RS09210	COG2963	transposase activity
BF29_RS09215	COG2801	Transposase and inactivated derivatives
BF29_RS09225	COG1301	dicarboxylic acid transport
BF29_RS09235	COG3711	transcriptional antiterminator
BF29_RS09240	COG2252	PERMEase
BF29_RS09250	COG1132	(ABC) transporter
BF29_RS09255	COG2814	Major facilitator Superfamily
BF29_RS09265	COG0471	metal ion transport
BF29_RS09305	COG3328	transposase activity
BF29_RS09315	COG1131	(ABC) transporter
BF29_RS09320	COG1725	Transcriptional regulator
BF29_RS09325	COG1695	Transcriptional regulator
BF29_RS09330	COG3479	Phenolic acid decarboxylase
BF29_RS09335	COG2910	NAD(P)H-binding
BF29_RS09340	COG1959	2 iron, 2 sulfur cluster binding
BF29_RS09350	COG0535	radical SAM domain protein
BF29_RS09355	COG1994	Peptidase M50
BF29_RS09360	COG1131	(ABC) transporter
BF29_RS09385	COG0425	Belongs to the sulfur carrier protein TusA family
BF29_RS09390	COG2391	methyltransferase activity
BF29_RS09395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF29_RS09400	COG1279	arginine transmembrane transporter activity
BF29_RS09425	COG0425	Belongs to the sulfur carrier protein TusA family
BF29_RS09430	COG2391	methyltransferase activity
BF29_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS09460	COG1120	ATPase activity
BF29_RS09465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF29_RS09500	COG3620	sequence-specific DNA binding
BF29_RS09515	COG0519	Catalyzes the synthesis of GMP from XMP
BF29_RS09515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BF29_RS09525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BF29_RS09530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF29_RS09535	COG1335	isochorismatase
BF29_RS09540	COG4948	Mandelate Racemase Muconate Lactonizing
BF29_RS09550	COG0463	Glycosyl transferase, family 2
BF29_RS09555	COG2246	polysaccharide biosynthetic process
BF29_RS09560	COG0459	protein refolding
BF29_RS09565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BF29_RS09570	COG1266	CAAX protease self-immunity
BF29_RS09580	COG0805	protein transport
BF29_RS09585	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BF29_RS09590	COG0488	(ABC) transporter
BF29_RS09600	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF29_RS09605	COG0456	acetyltransferase
BF29_RS09610	COG1214	PFAM Peptidase M22, glycoprotease
BF29_RS09615	COG0802	atpase or kinase
BF29_RS09700	COG3091	SprT-like family
BF29_RS09705	COG2183	response to ionizing radiation
BF29_RS09710	COG2208	phosphoserine phosphatase activity
BF29_RS09715	COG1191	sigma factor activity
BF29_RS09720	COG2172	sigma factor antagonist activity
BF29_RS09725	COG1366	Belongs to the anti-sigma-factor antagonist family
BF29_RS09730	COG2208	phosphoserine phosphatase activity
BF29_RS09735	COG2172	sigma factor antagonist activity
BF29_RS09740	COG1366	Belongs to the anti-sigma-factor antagonist family
BF29_RS09745	COG1366	Belongs to the anti-sigma-factor antagonist family
BF29_RS09755	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF29_RS09760	COG0864	Transcriptional regulator
BF29_RS09765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF29_RS09770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF29_RS09775	COG0736	holo-[acyl-carrier-protein] synthase activity
BF29_RS09780	COG0705	Rhomboid family
BF29_RS09795	COG0513	Belongs to the DEAD box helicase family
BF29_RS09800	COG1280	lysine exporter protein (LysE YggA)
BF29_RS09805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF29_RS09810	COG1609	Transcriptional regulator
BF29_RS09815	COG0366	Alpha amylase catalytic
BF29_RS09825	COG2182	Extracellular solute-binding protein
BF29_RS09830	COG1175	transmembrane transport
BF29_RS09835	COG3833	ABC-type maltose transport systems, permease component
BF29_RS09840	COG5521	maltodextrose utilization protein MalA
BF29_RS09845	COG1554	hydrolase, family 65, central catalytic
BF29_RS09855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF29_RS09860	COG1181	Belongs to the D-alanine--D-alanine ligase family
BF29_RS09880	COG1253	flavin adenine dinucleotide binding
BF29_RS09885	COG0789	Transcriptional regulator
BF29_RS09890	COG1253	flavin adenine dinucleotide binding
BF29_RS09905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF29_RS09920	COG0629	single-stranded DNA binding
BF29_RS09925	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF29_RS09930	COG4786	Flagellar basal body rod
BF29_RS09935	COG4786	Flagellar basal body rod
BF29_RS09940	COG1077	Cell shape determining protein MreB Mrl
BF29_RS09950	COG1609	Transcriptional regulator
BF29_RS09955	COG0739	heme binding
BF29_RS09960	COG2385	sporulation resulting in formation of a cellular spore
BF29_RS09965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF29_RS09975	COG4836	Membrane
BF29_RS09980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BF29_RS09985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BF29_RS09990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BF29_RS09995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BF29_RS10000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BF29_RS10010	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BF29_RS10015	COG0356	it plays a direct role in the translocation of protons across the membrane
BF29_RS10025	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BF29_RS10030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BF29_RS10040	COG4475	Protein of unknown function (DUF436)
BF29_RS10045	COG0698	ribose 5-phosphate isomerase
BF29_RS10050	COG0840	transmembrane signaling receptor activity
BF29_RS10100	COG1971	Probably functions as a manganese efflux pump
BF29_RS10105	COG0009	L-threonylcarbamoyladenylate synthase
BF29_RS10120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF29_RS10130	COG1435	thymidine kinase activity
BF29_RS10135	COG0254	rRNA binding
BF29_RS10140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF29_RS10145	COG1494	fructose-1,6-bisphosphatase
BF29_RS10150	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF29_RS10155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF29_RS10160	COG0191	fructose-bisphosphate aldolase activity
BF29_RS10165	COG2204	response regulator
BF29_RS10185	COG2963	transposase activity
BF29_RS10190	COG2801	Transposase and inactivated derivatives
BF29_RS10195	COG1131	(ABC) transporter
BF29_RS10200	COG1725	Transcriptional regulator
BF29_RS10205	COG0504	CTP synthase activity
BF29_RS10210	COG3343	RNA polymerase activity
BF29_RS10225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF29_RS10225	COG1703	isobutyryl-CoA mutase activity
BF29_RS10225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF29_RS10230	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF29_RS10230	COG1703	isobutyryl-CoA mutase activity
BF29_RS10230	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF29_RS10235	COG1309	transcriptional regulator
BF29_RS10240	COG1960	acyl-CoA dehydrogenase activity
BF29_RS10245	COG1960	acyl-CoA dehydrogenase activity
BF29_RS10250	COG0183	Belongs to the thiolase family
BF29_RS10255	COG2181	nitrate reductase activity
BF29_RS10255	COG0247	lactate metabolic process
BF29_RS10260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF29_RS10265	COG0018	arginyl-trna synthetase
BF29_RS10275	COG0010	Belongs to the arginase family
BF29_RS10280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF29_RS10290	COG1994	Peptidase M50
BF29_RS10300	COG3465	dGTPase activity
BF29_RS10305	COG1078	dGTPase activity
BF29_RS10315	COG0095	Lipoate-protein ligase
BF29_RS10325	COG0280	phosphate acetyltransferase
BF29_RS10330	COG3253	May function as heme-dependent peroxidase
BF29_RS10340	COG2963	transposase activity
BF29_RS10345	COG2801	Transposase and inactivated derivatives
BF29_RS10355	COG2363	Small membrane protein
BF29_RS10365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BF29_RS10390	COG3949	Membrane
BF29_RS10395	COG4948	Mandelate Racemase Muconate Lactonizing
BF29_RS10405	COG1473	amidohydrolase
BF29_RS10415	COG0351	phosphomethylpyrimidine kinase
BF29_RS10430	COG0561	phosphatase activity
BF29_RS10435	COG0514	ATP-dependent DNA helicase (RecQ)
BF29_RS10440	COG1785	Belongs to the alkaline phosphatase family
BF29_RS10445	COG1737	Transcriptional regulator
BF29_RS10455	COG5002	protein histidine kinase activity
BF29_RS10455	COG3850	Histidine kinase
BF29_RS10470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF29_RS10475	COG1346	cytolysis
BF29_RS10480	COG1380	Effector of murein hydrolase LrgA
BF29_RS10485	COG0583	DNA-binding transcription factor activity
BF29_RS10490	COG0367	asparagine synthase
BF29_RS10500	COG2801	Transposase and inactivated derivatives
BF29_RS10505	COG2963	transposase activity
BF29_RS10565	COG2966	Psort location CytoplasmicMembrane, score
BF29_RS10570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF29_RS10575	COG1966	Carbon starvation protein
BF29_RS10580	COG1464	Belongs to the NlpA lipoprotein family
BF29_RS10585	COG2011	ABC-type metal ion transport system permease component
BF29_RS10590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF29_RS10595	COG1119	ATPase activity
BF29_RS10610	COG0534	Mate efflux family protein
BF29_RS10620	COG1442	glycosyl transferase family 8
BF29_RS10625	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF29_RS10635	COG2814	Major facilitator Superfamily
BF29_RS10650	COG0028	Belongs to the TPP enzyme family
BF29_RS10675	COG3842	ATPase activity
BF29_RS10695	COG0584	glycerophosphoryl diester phosphodiesterase
BF29_RS10710	COG1132	(ABC) transporter
BF29_RS10720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BF29_RS10740	COG1366	Belongs to the anti-sigma-factor antagonist family
BF29_RS10775	COG1126	abc transporter atp-binding protein
BF29_RS10785	COG0765	amino acid transport
BF29_RS10805	COG0579	oxidoreductase
BF29_RS10880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BF29_RS10885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF29_RS10890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF29_RS10895	COG4853	Protein conserved in bacteria
BF29_RS10900	COG4863	YycH protein
BF29_RS10905	COG5002	protein histidine kinase activity
BF29_RS10910	COG0745	RESPONSE REGULATOR receiver
BF29_RS10925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BF29_RS10930	COG0305	Participates in initiation and elongation during chromosome replication
BF29_RS10935	COG0359	binds to the 23S rRNA
BF29_RS10940	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF29_RS10950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BF29_RS10960	COG0360	Binds together with S18 to 16S ribosomal RNA
BF29_RS10965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BF29_RS10970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF29_RS10970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF29_RS10975	COG0307	riboflavin synthase, alpha
BF29_RS10980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF29_RS10980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF29_RS10985	COG0012	GTP binding
BF29_RS10990	COG4481	Protein conserved in bacteria
BF29_RS10995	COG0668	transmembrane transport
BF29_RS11005	COG1811	Na channel or pump
BF29_RS11010	COG1475	DNA binding
BF29_RS11015	COG1192	Involved in chromosome partitioning
BF29_RS11020	COG1475	DNA binding
BF29_RS11025	COG0357	Ribosomal RNA small subunit methyltransferase G
BF29_RS11030	COG0445	tRNA wobble uridine modification
BF29_RS11035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF29_RS11045	COG1847	R3H domain protein
BF29_RS11050	COG0706	membrane insertase activity
BF29_RS11055	COG0594	ribonuclease P activity
BF29_RS11060	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BF29_RS11065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BF29_RS11070	COG0592	DNA-directed DNA polymerase activity
BF29_RS11080	COG2501	S4 domain
BF29_RS11085	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BF29_RS11095	COG0187	DNA topoisomerase II activity
BF29_RS11100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF29_RS11105	COG3437	response regulator, receiver
BF29_RS11140	COG1982	Orn Lys Arg decarboxylase major
BF29_RS11150	COG3870	Protein conserved in bacteria
BF29_RS11155	COG1728	Protein conserved in bacteria
BF29_RS11160	COG0470	DNA polymerase III
BF29_RS11165	COG1774	PSP1 C-terminal conserved region
BF29_RS11170	COG4467	Involved in initiation control of chromosome replication
BF29_RS11175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF29_RS11180	COG2827	Endonuclease containing a URI domain
BF29_RS11185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF29_RS11190	COG2002	toxin-antitoxin pair type II binding
BF29_RS11200	COG0084	hydrolase, TatD family'
BF29_RS11220	COG4466	Protein conserved in bacteria
BF29_RS11230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BF29_RS11235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF29_RS11240	COG0251	oxidation-reduction process
BF29_RS11250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BF29_RS11255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF29_RS11260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BF29_RS11275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF29_RS11285	COG2002	toxin-antitoxin pair type II binding
BF29_RS11290	COG2244	polysaccharide biosynthetic process
BF29_RS11295	COG3956	TIGRFAM MazG family protein
BF29_RS11300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF29_RS11320	COG1098	S1 RNA binding domain
BF29_RS11330	COG2208	phosphoserine phosphatase activity
BF29_RS11335	COG2304	oxidoreductase activity
BF29_RS11340	COG0515	serine threonine protein kinase
BF29_RS11345	COG0037	tRNA processing
BF29_RS11350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF29_RS11355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF29_RS11360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BF29_RS11365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BF29_RS11370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF29_RS11375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF29_RS11380	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF29_RS11385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF29_RS11475	COG0516	GMP reductase activity
BF29_RS11475	COG0517	IMP dehydrogenase activity
BF29_RS11490	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BF29_RS11500	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BF29_RS11515	COG1428	Deoxynucleoside kinase
BF29_RS11520	COG1428	Deoxynucleoside kinase
BF29_RS11535	COG0590	tRNA wobble adenosine to inosine editing
BF29_RS11540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF29_RS11545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BF29_RS11550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BF29_RS11595	COG3880	PFAM UvrB UvrC protein
BF29_RS11600	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BF29_RS11605	COG0542	response to heat
BF29_RS11610	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF29_RS11615	COG4956	integral membrane protein (PIN domain superfamily)
BF29_RS11625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BF29_RS11635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BF29_RS11640	COG1045	serine acetyltransferase
BF29_RS11645	COG0215	cysteine-tRNA ligase activity
BF29_RS11655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF29_RS11660	COG3688	RNA-binding protein containing a PIN domain
BF29_RS11675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF29_RS11680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF29_RS11685	COG0250	Participates in transcription elongation, termination and antitermination
BF29_RS11690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BF29_RS11695	COG0081	regulation of translation
BF29_RS11700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BF29_RS11710	COG2813	Specifically methylates the guanine in position
BF29_RS11715	COG0085	RNA polymerase activity
BF29_RS11725	COG1358	cellular component organization or biogenesis
BF29_RS11730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BF29_RS11735	COG0049	tRNA binding
BF29_RS11740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BF29_RS11745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BF29_RS11750	COG0051	transcription antitermination factor activity, RNA binding
BF29_RS11770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BF29_RS11775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BF29_RS11785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BF29_RS11790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BF29_RS11795	COG0255	Belongs to the universal ribosomal protein uL29 family
BF29_RS11805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BF29_RS11815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BF29_RS11820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BF29_RS11825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BF29_RS11830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF29_RS11835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BF29_RS11840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BF29_RS11850	COG0200	Binds to the 23S rRNA
BF29_RS11855	COG0201	protein transport
BF29_RS11860	COG0563	adenylate kinase activity
BF29_RS11865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BF29_RS11870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF29_RS11875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BF29_RS11880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BF29_RS11885	COG0202	RNA polymerase activity
BF29_RS11890	COG0203	ribosomal protein L17
BF29_RS11895	COG1122	ATPase activity
BF29_RS11900	COG1122	ATPase activity
BF29_RS11905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF29_RS11915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BF29_RS11920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BF29_RS11930	COG2046	Belongs to the sulfate adenylyltransferase family
BF29_RS11935	COG0529	Catalyzes the synthesis of activated sulfate
BF29_RS11940	COG0833	amino acid
BF29_RS11950	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF29_RS11955	COG0489	protein tyrosine kinase activity
BF29_RS11970	COG2194	sulfuric ester hydrolase activity
BF29_RS11990	COG0662	Cupin 2, conserved barrel domain protein
BF29_RS12015	COG0726	polysaccharide deacetylase
BF29_RS12025	COG1271	oxidase subunit
BF29_RS12030	COG1294	oxidase, subunit
BF29_RS12035	COG4988	ABC transporter
BF29_RS12040	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF29_RS12120	COG1525	nuclease
BF29_RS12145	COG3617	BRO family, N-terminal domain
BF29_RS12180	COG5377	YqaJ viral recombinase family
BF29_RS12185	COG3723	Recombinational DNA repair protein, rece pathway
BF29_RS12260	COG0175	sulfate reduction
BF29_RS12265	COG2963	transposase activity
BF29_RS12270	COG2801	Transposase and inactivated derivatives
BF29_RS12275	COG3677	Transposase
BF29_RS12285	COG5484	DNA packaging
BF29_RS12440	COG2333	competence protein COMEC
BF29_RS12440	COG0658	competence protein
BF29_RS12450	COG1525	nuclease
BF29_RS12475	COG3617	BRO family, N-terminal domain
BF29_RS12510	COG5377	YqaJ viral recombinase family
BF29_RS12515	COG3723	Recombinational DNA repair protein, rece pathway
BF29_RS12595	COG0175	sulfate reduction
BF29_RS12600	COG2963	transposase activity
BF29_RS12605	COG2801	Transposase and inactivated derivatives
BF29_RS12610	COG3677	Transposase
BF29_RS12620	COG5484	DNA packaging
BF29_RS12780	COG0658	competence protein
BF29_RS12780	COG2333	competence protein COMEC
BF29_RS12800	COG1595	DNA-templated transcription, initiation
BF29_RS12805	COG5662	AntiSigma factor
BF29_RS12810	COG2801	Transposase and inactivated derivatives
BF29_RS12815	COG2963	transposase activity
BF29_RS12825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF29_RS12830	COG4856	YbbR-like protein
BF29_RS12835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF29_RS12845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF29_RS12860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF29_RS12900	COG3425	synthase
BF29_RS12905	COG0183	Belongs to the thiolase family
BF29_RS12925	COG1125	glycine betaine transport
BF29_RS12925	COG0517	IMP dehydrogenase activity
BF29_RS12930	COG1174	glycine betaine transport
BF29_RS12935	COG2190	(PTS) system
BF29_RS12940	COG1263	PTS System
BF29_RS12940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF29_RS12945	COG0366	Alpha amylase catalytic
BF29_RS12950	COG2188	Transcriptional regulator
BF29_RS12965	COG1070	Carbohydrate kinase
BF29_RS12975	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF29_RS12980	COG0716	FMN binding
BF29_RS12985	COG0322	excinuclease ABC activity
BF29_RS12990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF29_RS12995	COG2217	Heavy metal translocating P-type atpase
BF29_RS13000	COG2217	Heavy metal translocating P-type atpase
BF29_RS13010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF29_RS13020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF29_RS13030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF29_RS13035	COG1215	transferase activity, transferring glycosyl groups
BF29_RS13050	COG2076	Multidrug Resistance protein
BF29_RS13055	COG2076	Multidrug Resistance protein
BF29_RS13065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF29_RS13070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF29_RS13075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF29_RS13080	COG1120	ATPase activity
BF29_RS13100	COG0217	transcriptional regulatory protein
BF29_RS13105	COG1366	Belongs to the anti-sigma-factor antagonist family
BF29_RS13110	COG1960	acyl-CoA dehydrogenase activity
BF29_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS13125	COG1309	transcriptional regulator
BF29_RS13185	COG3226	Transcriptional regulator
BF29_RS13200	COG1012	belongs to the aldehyde dehydrogenase family
BF29_RS13215	COG5434	Belongs to the glycosyl hydrolase 28 family
BF29_RS13225	COG0175	sulfate reduction
BF29_RS13250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF29_RS13260	COG0371	Dehydrogenase
BF29_RS13275	COG0318	PFAM AMP-dependent synthetase and ligase
BF29_RS13290	COG0697	spore germination
BF29_RS13320	COG1216	Glycosyl transferase, family 2
BF29_RS13320	COG1442	glycosyl transferase family 8
BF29_RS13325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BF29_RS13350	COG0702	epimerase
BF29_RS13370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF29_RS13390	COG2848	UPF0210 protein
BF29_RS13405	COG1609	Transcriptional regulator
BF29_RS13415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BF29_RS13425	COG5577	PFAM Coat F domain
BF29_RS13430	COG0667	Aldo Keto reductase
BF29_RS13440	COG1113	amino acid transport
BF29_RS13455	COG3104	oligopeptide transport
BF29_RS13460	COG0833	amino acid
BF29_RS13475	COG3842	ATPase activity
BF29_RS13480	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF29_RS13485	COG1177	transmembrane transport
BF29_RS13515	COG0531	amino acid
BF29_RS13520	COG1556	Lactate utilization protein
BF29_RS13525	COG1139	Iron-sulfur cluster binding protein
BF29_RS13530	COG0247	lactate metabolic process
BF29_RS13535	COG0531	amino acid
BF29_RS13540	COG1979	alcohol dehydrogenase
BF29_RS13545	COG0004	ammonium transporteR
BF29_RS13550	COG3290	protein histidine kinase activity
BF29_RS13555	COG4565	transcriptional regulatory protein
BF29_RS13560	COG2851	Citrate transporter
BF29_RS13570	COG0463	Glycosyl transferase, family 2
BF29_RS13575	COG3973	AAA domain
BF29_RS13615	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF29_RS13625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF29_RS13630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BF29_RS13635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF29_RS13640	COG1301	dicarboxylic acid transport
BF29_RS13645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF29_RS13655	COG2963	transposase activity
BF29_RS13660	COG2801	Transposase and inactivated derivatives
BF29_RS13685	COG1902	pentaerythritol trinitrate reductase activity
BF29_RS13700	COG0423	glycine-tRNA ligase activity
BF29_RS13705	COG0531	amino acid
BF29_RS13715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BF29_RS13720	COG0628	permease
BF29_RS13740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF29_RS13745	COG0765	amino acid transport
BF29_RS13750	COG0765	amino acid transport
BF29_RS13765	COG1733	regulation of RNA biosynthetic process
BF29_RS13775	COG0586	Pfam SNARE associated Golgi protein
BF29_RS13780	COG0586	Pfam SNARE associated Golgi protein
BF29_RS13800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF29_RS13800	COG0646	methionine synthase
BF29_RS13805	COG1410	methionine synthase
BF29_RS13805	COG0646	methionine synthase
BF29_RS13835	COG3944	biosynthesis protein
BF29_RS13840	COG0489	protein tyrosine kinase activity
BF29_RS13845	COG4464	protein tyrosine phosphatase activity
BF29_RS13850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF29_RS13855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF29_RS13870	COG1216	Glycosyl transferase, family 2
BF29_RS13870	COG1442	glycosyl transferase family 8
BF29_RS13875	COG1216	Glycosyl transferase, family 2
BF29_RS13875	COG1442	glycosyl transferase family 8
BF29_RS13940	COG1070	Carbohydrate kinase
BF29_RS13945	COG1063	alcohol dehydrogenase
BF29_RS13950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF29_RS13965	COG4193	domain, Protein
BF29_RS13970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BF29_RS13980	COG5504	Zn-dependent protease
BF29_RS13995	COG0366	Alpha amylase catalytic
BF29_RS13995	COG5263	repeat protein
BF29_RS14025	COG2315	Protein conserved in bacteria
BF29_RS14035	COG2333	competence protein COMEC
BF29_RS14035	COG0658	competence protein
BF29_RS14090	COG0531	amino acid
BF29_RS14100	COG1316	TRANSCRIPTIONal
BF29_RS14115	COG4989	oxidoreductase activity
BF29_RS14130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BF29_RS14135	COG2130	NADP-dependent
BF29_RS14160	COG2190	(PTS) system
BF29_RS14160	COG2211	Major facilitator Superfamily
BF29_RS14175	COG2814	Major facilitator Superfamily
BF29_RS14200	COG2814	Major facilitator Superfamily
BF29_RS14205	COG1609	Transcriptional regulator
BF29_RS14225	COG1174	glycine betaine transport
BF29_RS14230	COG1732	Glycine betaine
BF29_RS14235	COG1174	glycine betaine transport
BF29_RS14240	COG0517	IMP dehydrogenase activity
BF29_RS14240	COG1125	glycine betaine transport
BF29_RS14245	COG1510	regulation of RNA biosynthetic process
BF29_RS14250	COG0110	maltose O-acetyltransferase activity
BF29_RS14270	COG4297	protein containing double-stranded beta helix domain
BF29_RS14280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF29_RS14285	COG2272	Belongs to the type-B carboxylesterase lipase family
BF29_RS14290	COG0606	chelatase, subunit chli
BF29_RS14300	COG0371	Dehydrogenase
BF29_RS14310	COG0157	Belongs to the NadC ModD family
BF29_RS14315	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF29_RS14320	COG1104	cysteine desulfurase activity
BF29_RS14340	COG1131	(ABC) transporter
BF29_RS14370	COG4720	Psort location CytoplasmicMembrane, score
BF29_RS14405	COG0584	glycerophosphoryl diester phosphodiesterase
BF29_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF29_RS14455	COG0737	Belongs to the 5'-nucleotidase family
BF29_RS14460	COG1363	Peptidase, m42
BF29_RS14480	COG1620	l-lactate permease
BF29_RS14485	COG2186	Transcriptional regulator
BF29_RS14545	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF29_RS14565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF29_RS14565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF29_RS14570	COG2723	6-phospho-beta-galactosidase activity
BF29_RS14580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF29_RS14580	COG3711	transcriptional antiterminator
BF29_RS14585	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BF29_RS14595	COG0626	cystathionine gamma-synthase activity
BF29_RS14600	COG0626	cystathionine gamma-synthase activity
BF29_RS14620	COG1653	transport
BF29_RS14625	COG2207	Transcriptional regulator
BF29_RS14640	COG0604	alcohol dehydrogenase
BF29_RS14645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF29_RS14650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF29_RS14680	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BF29_RS14690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF29_RS14700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF29_RS14705	COG1316	TRANSCRIPTIONal
BF29_RS14710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF29_RS14715	COG1554	hydrolase, family 65, central catalytic
BF29_RS14725	COG1609	Transcriptional regulator
BF29_RS14730	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BF29_RS14745	COG3584	3D domain protein
BF29_RS14745	COG1388	LysM domain
BF29_RS14755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF29_RS14770	COG0011	TIGRFAM Protein of
BF29_RS14775	COG2706	6-phosphogluconolactonase activity
BF29_RS14790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF29_RS14790	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF29_RS14795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF29_RS14795	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF29_RS14805	COG3715	PTS system
BF29_RS14810	COG3716	PTS system mannose fructose sorbose family IID component
BF29_RS14825	COG2079	MmgE PrpD family protein
BF29_RS14830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF29_RS14840	COG0154	amidase activity
BF29_RS14850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF29_RS14855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF29_RS14860	COG1116	anion transmembrane transporter activity
BF29_RS14865	COG0083	homoserine kinase activity
BF29_RS14870	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BF29_RS14875	COG0460	homoserine dehydrogenase
BF29_RS14880	COG0010	Belongs to the arginase family
BF29_RS14890	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BF29_RS14895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF29_RS14905	COG4145	pantothenate transmembrane transporter activity
BF29_RS14920	COG1454	alcohol dehydrogenase
BF29_RS14920	COG1012	belongs to the aldehyde dehydrogenase family
BF29_RS14935	COG0791	NLP P60 protein
BF29_RS14935	COG1388	LysM domain
BF29_RS14940	COG0024	Methionine aminopeptidase
BF29_RS14945	COG1268	BioY protein
BF29_RS14965	COG2323	membrane
BF29_RS14975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF29_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS14990	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF29_RS14995	COG2244	polysaccharide biosynthetic process
BF29_RS15000	COG0589	response to stress
BF29_RS15015	COG0535	radical SAM domain protein
BF29_RS15025	COG0561	phosphatase activity
BF29_RS15045	COG0431	NADPH-dependent FMN reductase
BF29_RS15060	COG0420	3'-5' exonuclease activity
BF29_RS15065	COG4717	serine-type aminopeptidase activity
BF29_RS15075	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF29_RS15080	COG0534	Mate efflux family protein
BF29_RS15090	COG0789	Transcriptional regulator
BF29_RS15095	COG0436	Aminotransferase
BF29_RS15100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF29_RS15110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF29_RS15155	COG0798	PFAM Bile acid sodium symporter
BF29_RS15165	COG2226	methyltransferase
BF29_RS15180	COG1090	epimerase
BF29_RS15185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF29_RS15205	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF29_RS15220	COG1960	acyl-CoA dehydrogenase activity
BF29_RS15235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF29_RS15240	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BF29_RS15250	COG2017	converts alpha-aldose to the beta-anomer
BF29_RS15255	COG1609	Transcriptional regulator
BF29_RS15280	COG2996	Protein conserved in bacteria
BF29_RS15285	COG0346	lactoylglutathione lyase activity
BF29_RS15290	COG1482	cell wall glycoprotein biosynthetic process
BF29_RS15300	COG0477	Major facilitator Superfamily
BF29_RS15305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF29_RS15315	COG2188	Transcriptional regulator
BF29_RS15320	COG0791	NLP P60 protein
BF29_RS15320	COG1388	LysM domain
BF29_RS15335	COG0768	penicillin binding
BF29_RS15340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF29_RS15345	COG1739	Uncharacterized protein family UPF0029
BF29_RS15355	COG2197	response regulator
BF29_RS15365	COG0531	amino acid
BF29_RS15370	COG1307	EDD domain protein, DegV family
BF29_RS15375	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF29_RS15380	COG1040	competence protein
BF29_RS15390	COG2747	anti-sigma28 factor FlgM
BF29_RS15400	COG1256	bacterial-type flagellum assembly
BF29_RS15400	COG4786	Flagellar basal body rod
BF29_RS15405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF29_RS15415	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BF29_RS15430	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF29_RS15435	COG1285	pathogenesis
BF29_RS15440	COG0647	UMP catabolic process
BF29_RS15450	COG2271	Major facilitator Superfamily
BF29_RS15455	COG1113	amino acid transport
BF29_RS15460	COG1067	ATP-dependent peptidase activity
BF29_RS15500	COG2094	Belongs to the DNA glycosylase MPG family
BF29_RS15510	COG1334	flagellar protein FlaG
BF29_RS15515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BF29_RS15520	COG1516	flagellar protein fliS
BF29_RS15535	COG0405	Gamma-glutamyltransferase
BF29_RS15550	COG0653	protein targeting
BF29_RS15555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF29_RS15560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF29_RS15570	COG2884	Cell division ATP-binding protein ftsE
BF29_RS15575	COG2177	Part of the ABC transporter FtsEX involved in
BF29_RS15580	COG0739	heme binding
BF29_RS15595	COG0460	homoserine dehydrogenase
BF29_RS15605	COG3409	Peptidoglycan-binding domain 1 protein
BF29_RS15605	COG0793	Belongs to the peptidase S41A family
BF29_RS15610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF29_RS15615	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF29_RS15620	COG4605	iron ion homeostasis
BF29_RS15625	COG4604	ABC transporter, ATP-binding protein
BF29_RS15630	COG4607	ABC-type enterochelin transport system periplasmic component
BF29_RS15655	COG0745	RESPONSE REGULATOR receiver
BF29_RS15660	COG5002	protein histidine kinase activity
BF29_RS15665	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF29_RS15675	COG0573	inorganic phosphate transmembrane transporter activity
BF29_RS15680	COG0581	inorganic phosphate transmembrane transporter activity
BF29_RS15685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF29_RS15690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF29_RS15715	COG0556	nucleotide-excision repair
BF29_RS15720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF29_RS15725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BF29_RS15735	COG0463	Glycosyl transferase, family 2
BF29_RS15765	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BF29_RS15770	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BF29_RS15775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BF29_RS15780	COG1682	transport, permease protein
BF29_RS15790	COG3595	metallopeptidase activity
BF29_RS15800	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BF29_RS15810	COG0546	phosphoglycolate phosphatase activity
BF29_RS15815	COG0110	maltose O-acetyltransferase activity
BF29_RS15820	COG0457	Tetratricopeptide repeat
BF29_RS15825	COG0492	ferredoxin-NADP+ reductase activity
BF29_RS15835	COG1051	belongs to the nudix hydrolase family
BF29_RS15840	COG1660	Displays ATPase and GTPase activities
BF29_RS15845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF29_RS15850	COG1481	regulation of sporulation
BF29_RS15855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF29_RS15895	COG3842	ATPase activity
BF29_RS15905	COG2508	Transcriptional regulator
BF29_RS15915	COG0189	ligase activity
BF29_RS15920	COG0189	ligase activity
BF29_RS15935	COG4399	Belongs to the UPF0754 family
BF29_RS15945	COG0561	phosphatase activity
BF29_RS15950	COG1024	Enoyl-CoA hydratase
BF29_RS15960	COG0861	Integral membrane protein TerC family
BF29_RS15965	COG0701	Predicted permease
BF29_RS15970	COG3689	TIGRFAM TIGR03943 family protein
BF29_RS15975	COG0420	3'-5' exonuclease activity
BF29_RS15980	COG4717	serine-type aminopeptidase activity
BF29_RS15985	COG3481	metal-dependent phosphohydrolase, HD sub domain
BF29_RS15995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF29_RS16010	COG1846	Transcriptional regulator
BF29_RS16035	COG0537	adenosine 5'-monophosphoramidase activity
BF29_RS16040	COG1131	(ABC) transporter
BF29_RS16045	COG4473	ABC transporter
BF29_RS16055	COG1473	amidohydrolase
BF29_RS16060	COG3069	C4-dicarboxylate transmembrane transporter activity
BF29_RS16070	COG2329	Antibiotic biosynthesis monooxygenase
BF29_RS16075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF29_RS16080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF29_RS16085	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF29_RS16095	COG1309	transcriptional regulator
BF29_RS16100	COG1511	domain protein
BF29_RS16105	COG2814	Major facilitator Superfamily
BF29_RS16110	COG0697	spore germination
BF29_RS16115	COG1012	belongs to the aldehyde dehydrogenase family
BF29_RS16120	COG1999	signal sequence binding
BF29_RS16130	COG0095	Lipoate-protein ligase
BF29_RS16135	COG0318	PFAM AMP-dependent synthetase and ligase
BF29_RS16145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BF29_RS16155	COG0501	Belongs to the peptidase M48B family
BF29_RS16165	COG4903	ComK protein
BF29_RS16180	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF29_RS16185	COG1074	ATP-dependent DNA helicase activity
BF29_RS16220	COG2311	Membrane
BF29_RS16225	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF29_RS16245	COG1307	EDD domain protein, DegV family
BF29_RS16255	COG0561	phosphatase activity
BF29_RS16260	COG2151	metal-sulfur cluster biosynthetic enzyme
BF29_RS16295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF29_RS16300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF29_RS16320	COG4608	Belongs to the ABC transporter superfamily
BF29_RS16325	COG0601	transmembrane transport
BF29_RS16345	COG0180	Tryptophanyl-tRNA synthetase
BF29_RS16360	COG4166	transmembrane transport
BF29_RS16365	COG0601	transmembrane transport
BF29_RS16370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF29_RS16375	COG0444	Belongs to the ABC transporter superfamily
BF29_RS16380	COG4608	Belongs to the ABC transporter superfamily
BF29_RS16385	COG1393	Belongs to the ArsC family
BF29_RS16395	COG4862	establishment of competence for transformation
BF29_RS16400	COG4469	Competence protein
BF29_RS16405	COG1164	Oligoendopeptidase f
BF29_RS16415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF29_RS16420	COG2346	COG2346, Truncated hemoglobins
BF29_RS16425	COG0741	lytic transglycosylase activity
BF29_RS16430	COG4116	CYTH
BF29_RS16440	COG2357	RelA SpoT domain protein
BF29_RS16450	COG0564	pseudouridine synthase activity
BF29_RS16455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF29_RS16460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BF29_RS16500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF29_RS16525	COG2153	protein acetylation
BF29_RS16535	COG2382	esterase
BF29_RS16545	COG1940	carbohydrate kinase activity
BF29_RS16555	COG4152	abc transporter atp-binding protein
BF29_RS16560	COG1668	transmembrane transport
BF29_RS16575	COG3579	cysteine-type endopeptidase activity
BF29_RS16600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF29_RS16605	COG2059	Chromate
BF29_RS16610	COG2059	Chromate
BF29_RS16615	COG1522	sequence-specific DNA binding
BF29_RS16635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF29_RS16640	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BF29_RS16670	COG2963	transposase activity
BF29_RS16675	COG2801	Transposase and inactivated derivatives
BF29_RS16680	COG2323	membrane
BF29_RS16700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF29_RS16730	COG0477	Major facilitator Superfamily
BF29_RS16745	COG1959	2 iron, 2 sulfur cluster binding
BF29_RS16760	COG0730	response to heat
BF29_RS16765	COG0783	Belongs to the Dps family
BF29_RS16770	COG0673	inositol 2-dehydrogenase activity
BF29_RS16775	COG3852	Histidine kinase
BF29_RS16780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BF29_RS16790	COG0861	Integral membrane protein TerC family
BF29_RS16805	COG5002	protein histidine kinase activity
BF29_RS16810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF29_RS16830	COG0542	response to heat
BF29_RS16835	COG3949	Membrane
BF29_RS16850	COG4873	Protein conserved in bacteria
BF29_RS16865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF29_RS16880	COG2084	Dehydrogenase
BF29_RS16885	COG0436	Aminotransferase
BF29_RS16890	COG0784	Response regulator, receiver
BF29_RS16890	COG0835	chemotaxis
BF29_RS16900	COG1033	growth of symbiont in host cell
BF29_RS16900	COG2409	Drug exporters of the RND superfamily
BF29_RS16905	COG3300	MHYT domain
BF29_RS16905	COG5001	Diguanylate cyclase
BF29_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
BF29_RS16930	COG4703	Protein of unknown function (DUF1797)
BF29_RS16935	COG0517	IMP dehydrogenase activity
BF29_RS16965	COG0697	spore germination
BF29_RS16970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF29_RS16995	COG4372	Transposase
BF29_RS17000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein