locus-tag	class	description
CG479_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG479_RS00010	COG0592	DNA-directed DNA polymerase activity
CG479_RS00015	COG2501	S4 domain
CG479_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG479_RS00025	COG0187	DNA topoisomerase II activity
CG479_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG479_RS00065	COG0517	IMP dehydrogenase activity
CG479_RS00065	COG0516	GMP reductase activity
CG479_RS00070	COG1686	Belongs to the peptidase S11 family
CG479_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CG479_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG479_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG479_RS00100	COG1428	Deoxynucleoside kinase
CG479_RS00105	COG1428	Deoxynucleoside kinase
CG479_RS00110	COG1335	isochorismatase
CG479_RS00115	COG0590	tRNA wobble adenosine to inosine editing
CG479_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG479_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG479_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG479_RS00180	COG1982	Orn Lys Arg decarboxylase major
CG479_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG479_RS00190	COG0470	DNA polymerase III
CG479_RS00195	COG1774	PSP1 C-terminal conserved region
CG479_RS00200	COG4467	Involved in initiation control of chromosome replication
CG479_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CG479_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG479_RS00220	COG2002	toxin-antitoxin pair type II binding
CG479_RS00230	COG0084	hydrolase, TatD family'
CG479_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG479_RS00250	COG4466	Protein conserved in bacteria
CG479_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG479_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG479_RS00270	COG0251	oxidation-reduction process
CG479_RS00275	COG2088	sporulation resulting in formation of a cellular spore
CG479_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG479_RS00290	COG0193	aminoacyl-tRNA hydrolase activity
CG479_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG479_RS00305	COG2002	toxin-antitoxin pair type II binding
CG479_RS00310	COG2244	polysaccharide biosynthetic process
CG479_RS00315	COG3956	TIGRFAM MazG family protein
CG479_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG479_RS00340	COG1098	S1 RNA binding domain
CG479_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CG479_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG479_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG479_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG479_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG479_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG479_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
CG479_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG479_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG479_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG479_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG479_RS00420	COG1396	sequence-specific DNA binding
CG479_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG479_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG479_RS00465	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG479_RS00515	COG3880	PFAM UvrB UvrC protein
CG479_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CG479_RS00525	COG0542	response to heat
CG479_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CG479_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
CG479_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG479_RS00550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG479_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG479_RS00560	COG1045	serine acetyltransferase
CG479_RS00565	COG0215	cysteine-tRNA ligase activity
CG479_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG479_RS00580	COG3688	RNA-binding protein containing a PIN domain
CG479_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG479_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
CG479_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CG479_RS00610	COG0081	regulation of translation
CG479_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG479_RS00620	COG0222	ribosome binding
CG479_RS00625	COG2813	Specifically methylates the guanine in position
CG479_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG479_RS00640	COG1358	cellular component organization or biogenesis
CG479_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG479_RS00650	COG0049	tRNA binding
CG479_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG479_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG479_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG479_RS00675	COG0088	Forms part of the polypeptide exit tunnel
CG479_RS00680	COG0089	rRNA binding
CG479_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG479_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG479_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG479_RS00700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG479_RS00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG479_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
CG479_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG479_RS00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG479_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG479_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG479_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG479_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG479_RS00755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG479_RS00760	COG1841	ribosomal large subunit assembly
CG479_RS00765	COG0200	Binds to the 23S rRNA
CG479_RS00770	COG0201	protein transport
CG479_RS00775	COG0563	adenylate kinase activity
CG479_RS00780	COG0024	Methionine aminopeptidase
CG479_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG479_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CG479_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG479_RS00805	COG0202	RNA polymerase activity
CG479_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG479_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG479_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG479_RS00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG479_RS00860	COG0489	protein tyrosine kinase activity
CG479_RS00870	COG2194	sulfuric ester hydrolase activity
CG479_RS00875	COG0726	polysaccharide deacetylase
CG479_RS00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CG479_RS00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG479_RS00990	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG479_RS01000	COG0489	protein tyrosine kinase activity
CG479_RS01005	COG0019	diaminopimelate decarboxylase activity
CG479_RS01025	COG1266	CAAX protease self-immunity
CG479_RS01105	COG3681	Belongs to the UPF0597 family
CG479_RS01110	COG3681	Belongs to the UPF0597 family
CG479_RS01135	COG2814	Major facilitator Superfamily
CG479_RS01145	COG0601	transmembrane transport
CG479_RS01150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG479_RS01155	COG0444	Belongs to the ABC transporter superfamily
CG479_RS01160	COG4608	Belongs to the ABC transporter superfamily
CG479_RS01165	COG4166	transmembrane transport
CG479_RS01185	COG1309	transcriptional regulator
CG479_RS01195	COG0656	L-ascorbic acid biosynthetic process
CG479_RS01200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG479_RS01210	COG4149	molybdate abc transporter
CG479_RS01215	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG479_RS01220	COG1910	domain protein
CG479_RS01225	COG0204	Acyl-transferase
CG479_RS01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS01235	COG1648	precorrin-2 dehydrogenase activity
CG479_RS01235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG479_RS01245	COG1587	Uroporphyrinogen-III synthase
CG479_RS01245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG479_RS01250	COG2146	nitrite reductase [NAD(P)H] activity
CG479_RS01255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG479_RS01285	COG4585	Histidine kinase
CG479_RS01290	COG2197	response regulator
CG479_RS01295	COG1131	(ABC) transporter
CG479_RS01300	COG1511	domain protein
CG479_RS01300	COG0842	Transport permease protein
CG479_RS01305	COG0842	Transport permease protein
CG479_RS01315	COG0747	negative chemotaxis
CG479_RS01320	COG0601	transmembrane transport
CG479_RS01325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG479_RS01330	COG0444	Belongs to the ABC transporter superfamily
CG479_RS01335	COG4608	Belongs to the ABC transporter superfamily
CG479_RS01340	COG0561	phosphatase activity
CG479_RS01360	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CG479_RS01365	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG479_RS01375	COG2814	Major facilitator Superfamily
CG479_RS01380	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG479_RS01385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG479_RS01395	COG0705	Rhomboid family
CG479_RS01395	COG0457	Tetratricopeptide repeat
CG479_RS01400	COG0736	holo-[acyl-carrier-protein] synthase activity
CG479_RS01405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG479_RS01415	COG0864	Transcriptional regulator
CG479_RS01420	COG2337	Toxic component of a toxin-antitoxin (TA) module
CG479_RS01425	COG2183	response to ionizing radiation
CG479_RS01435	COG3091	SprT-like family
CG479_RS01475	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG479_RS01525	COG0802	atpase or kinase
CG479_RS01530	COG1214	PFAM Peptidase M22, glycoprotease
CG479_RS01535	COG0456	acetyltransferase
CG479_RS01545	COG0488	(ABC) transporter
CG479_RS01550	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CG479_RS01560	COG1266	CAAX protease self-immunity
CG479_RS01565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG479_RS01570	COG0459	protein refolding
CG479_RS01575	COG0519	Catalyzes the synthesis of GMP from XMP
CG479_RS01575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG479_RS01580	COG2252	PERMEase
CG479_RS01590	COG5002	protein histidine kinase activity
CG479_RS01660	COG2205	protein histidine kinase activity
CG479_RS01665	COG0745	RESPONSE REGULATOR receiver
CG479_RS01685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG479_RS01690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG479_RS01695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG479_RS01700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG479_RS01705	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG479_RS01710	COG0047	phosphoribosylformylglycinamidine synthase activity
CG479_RS01715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG479_RS01720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG479_RS01725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG479_RS01730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG479_RS01735	COG0138	bifunctional purine biosynthesis protein purh
CG479_RS01740	COG0151	Belongs to the GarS family
CG479_RS01750	COG0583	DNA-binding transcription factor activity
CG479_RS01770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CG479_RS01775	COG0210	DNA helicase
CG479_RS01780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG479_RS01785	COG4851	CamS sex pheromone cAM373 precursor
CG479_RS01795	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS01800	COG1335	isochorismatase
CG479_RS01810	COG2011	ABC-type metal ion transport system permease component
CG479_RS01830	COG4682	membrane
CG479_RS01835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG479_RS01840	COG0154	amidase activity
CG479_RS01845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG479_RS01850	COG1597	lipid kinase activity
CG479_RS01855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG479_RS01860	COG0546	phosphoglycolate phosphatase activity
CG479_RS01865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG479_RS01875	COG0531	amino acid
CG479_RS01880	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS01885	COG2076	Multidrug Resistance protein
CG479_RS01890	COG2309	aminopeptidase activity
CG479_RS01900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG479_RS01905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG479_RS01910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG479_RS01925	COG0450	alkyl hydroperoxide reductase
CG479_RS01950	COG0714	Associated with various cellular activities
CG479_RS01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS01995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG479_RS02000	COG0492	ferredoxin-NADP+ reductase activity
CG479_RS02010	COG0166	Belongs to the GPI family
CG479_RS02040	COG3541	Predicted nucleotidyltransferase
CG479_RS02045	COG2814	Major facilitator Superfamily
CG479_RS02050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG479_RS02050	COG0723	plastoquinol--plastocyanin reductase activity
CG479_RS02060	COG0765	amino acid transport
CG479_RS02065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG479_RS02075	COG0840	transmembrane signaling receptor activity
CG479_RS02085	COG2235	arginine
CG479_RS02100	COG0549	Belongs to the carbamate kinase family
CG479_RS02105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG479_RS02115	COG0366	Alpha amylase catalytic
CG479_RS02120	COG1263	PTS System
CG479_RS02120	COG2190	(PTS) system
CG479_RS02120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG479_RS02140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS02145	COG4605	iron ion homeostasis
CG479_RS02150	COG4604	ABC transporter, ATP-binding protein
CG479_RS02155	COG4607	ABC-type enterochelin transport system periplasmic component
CG479_RS02160	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CG479_RS02165	COG0352	thiamine-phosphate diphosphorylase activity
CG479_RS02170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG479_RS02190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG479_RS02200	COG1116	anion transmembrane transporter activity
CG479_RS02240	COG2270	Major facilitator Superfamily
CG479_RS02265	COG2310	stress, protein
CG479_RS02270	COG2310	stress, protein
CG479_RS02275	COG2310	stress, protein
CG479_RS02280	COG0861	Integral membrane protein TerC family
CG479_RS02290	COG3853	Toxic anion resistance protein (TelA)
CG479_RS02300	COG4840	Belongs to the UPF0435 family
CG479_RS02305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG479_RS02315	COG1295	ribonuclease BN
CG479_RS02320	COG2217	Heavy metal translocating P-type atpase
CG479_RS02325	COG0697	spore germination
CG479_RS02335	COG0681	Belongs to the peptidase S26 family
CG479_RS02345	COG0586	Pfam SNARE associated Golgi protein
CG479_RS02360	COG0387	Pfam Sodium calcium exchanger
CG479_RS02370	COG0535	radical SAM domain protein
CG479_RS02390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CG479_RS02415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG479_RS02470	COG2066	Belongs to the glutaminase family
CG479_RS02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG479_RS02475	COG1263	PTS System
CG479_RS02480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG479_RS02490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG479_RS02490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG479_RS02500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG479_RS02505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG479_RS02520	COG0402	S-adenosylhomocysteine deaminase activity
CG479_RS02525	COG2137	regulation of response to DNA damage stimulus
CG479_RS02550	COG1988	membrane-bound metal-dependent
CG479_RS02555	COG1194	a g-specific adenine glycosylase
CG479_RS02580	COG3557	Belongs to the UPF0374 family
CG479_RS02585	COG1132	(ABC) transporter
CG479_RS02590	COG4129	membrane
CG479_RS02595	COG0070	glutamate synthase
CG479_RS02595	COG0069	glutamate synthase activity
CG479_RS02595	COG0067	glutamate synthase
CG479_RS02600	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG479_RS02605	COG4555	ABC transporter
CG479_RS02625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG479_RS02630	COG0735	belongs to the Fur family
CG479_RS02750	COG0457	Tetratricopeptide repeat
CG479_RS02755	COG0217	transcriptional regulatory protein
CG479_RS02760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG479_RS02765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG479_RS02785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG479_RS02795	COG2766	serine protein kinase
CG479_RS02805	COG2718	Belongs to the UPF0229 family
CG479_RS02820	COG1280	lysine exporter protein (LysE YggA)
CG479_RS02860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG479_RS02870	COG1585	Membrane protein implicated in regulation of membrane protease activity
CG479_RS02875	COG2268	Band 7 protein
CG479_RS02900	COG4990	cell redox homeostasis
CG479_RS02910	COG3290	protein histidine kinase activity
CG479_RS02915	COG4565	transcriptional regulatory protein
CG479_RS02920	COG3493	citrate carrier protein
CG479_RS02925	COG0281	malic enzyme
CG479_RS02940	COG5002	protein histidine kinase activity
CG479_RS02945	COG0745	RESPONSE REGULATOR receiver
CG479_RS02955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG479_RS02960	COG3383	formate dehydrogenase (NAD+) activity
CG479_RS02965	COG2427	Protein of unknown function (DUF1641)
CG479_RS02975	COG0840	transmembrane signaling receptor activity
CG479_RS02985	COG0531	amino acid
CG479_RS03000	COG0640	Transcriptional regulator
CG479_RS03005	COG2217	Heavy metal translocating P-type atpase
CG479_RS03010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG479_RS03020	COG3227	Zinc metalloprotease (Elastase)
CG479_RS03035	COG2217	Heavy metal translocating P-type atpase
CG479_RS03055	COG2720	vancomycin resistance protein
CG479_RS03060	COG1316	TRANSCRIPTIONal
CG479_RS03070	COG1253	flavin adenine dinucleotide binding
CG479_RS03075	COG1027	Aspartate ammonia-lyase
CG479_RS03080	COG1620	l-lactate permease
CG479_RS03100	COG3104	oligopeptide transport
CG479_RS03105	COG0156	8-amino-7-oxononanoate synthase activity
CG479_RS03110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG479_RS03115	COG4548	von Willebrand factor, type A
CG479_RS03120	COG0714	Associated with various cellular activities
CG479_RS03125	COG0531	amino acid
CG479_RS03135	COG1115	amino acid carrier protein
CG479_RS03145	COG1126	abc transporter atp-binding protein
CG479_RS03150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG479_RS03155	COG0765	amino acid transport
CG479_RS03160	COG0765	amino acid transport
CG479_RS03165	COG0833	amino acid
CG479_RS03175	COG5002	protein histidine kinase activity
CG479_RS03180	COG0745	RESPONSE REGULATOR receiver
CG479_RS03190	COG0659	secondary active sulfate transmembrane transporter activity
CG479_RS03195	COG0589	response to stress
CG479_RS03205	COG0747	negative chemotaxis
CG479_RS03215	COG0601	transmembrane transport
CG479_RS03220	COG4608	Belongs to the ABC transporter superfamily
CG479_RS03230	COG2271	Major facilitator Superfamily
CG479_RS03235	COG1846	Transcriptional regulator
CG479_RS03240	COG0477	Major facilitator Superfamily
CG479_RS03245	COG1609	Transcriptional regulator
CG479_RS03250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG479_RS03255	COG1869	D-ribose catabolic process
CG479_RS03265	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG479_RS03270	COG1879	ABC-type sugar transport system periplasmic component
CG479_RS03275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG479_RS03290	COG3568	Endonuclease Exonuclease Phosphatase
CG479_RS03315	COG0840	transmembrane signaling receptor activity
CG479_RS03320	COG1388	LysM domain
CG479_RS03320	COG3584	3D domain protein
CG479_RS03325	COG1476	TRANSCRIPTIONal
CG479_RS03360	COG1114	Component of the transport system for branched-chain amino acids
CG479_RS03370	COG1113	amino acid transport
CG479_RS03375	COG2153	protein acetylation
CG479_RS03385	COG0475	glutathione-regulated potassium exporter activity
CG479_RS03385	COG0569	domain protein
CG479_RS03400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG479_RS03405	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG479_RS03410	COG0833	amino acid
CG479_RS03415	COG4990	cell redox homeostasis
CG479_RS03430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS03435	COG0697	spore germination
CG479_RS03440	COG0531	amino acid
CG479_RS03450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG479_RS03455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG479_RS03460	COG1918	ferrous iron import across plasma membrane
CG479_RS03460	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG479_RS03465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG479_RS03470	COG0573	inorganic phosphate transmembrane transporter activity
CG479_RS03475	COG0581	inorganic phosphate transmembrane transporter activity
CG479_RS03480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG479_RS03520	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG479_RS03595	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CG479_RS03620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG479_RS03625	COG1116	anion transmembrane transporter activity
CG479_RS03630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG479_RS03635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG479_RS03640	COG0352	thiamine-phosphate diphosphorylase activity
CG479_RS03645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG479_RS03650	COG2104	thiamine diphosphate biosynthetic process
CG479_RS03655	COG2022	thiamine diphosphate biosynthetic process
CG479_RS03660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG479_RS03665	COG0351	phosphomethylpyrimidine kinase
CG479_RS03695	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG479_RS03700	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG479_RS03705	COG2205	protein histidine kinase activity
CG479_RS03710	COG2814	Major facilitator Superfamily
CG479_RS03715	COG1846	Transcriptional regulator
CG479_RS03725	COG2252	PERMEase
CG479_RS03730	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS03735	COG1376	ErfK ybiS ycfS ynhG family protein
CG479_RS03790	COG0778	Nitroreductase
CG479_RS03800	COG2719	SpoVR family
CG479_RS03810	COG1316	TRANSCRIPTIONal
CG479_RS03815	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG479_RS03830	COG0577	efflux transmembrane transporter activity
CG479_RS03835	COG1136	(ABC) transporter
CG479_RS03845	COG1114	Component of the transport system for branched-chain amino acids
CG479_RS03850	COG3546	catalase activity
CG479_RS03905	COG0475	glutathione-regulated potassium exporter activity
CG479_RS03910	COG1737	Transcriptional regulator
CG479_RS03920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG479_RS03925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG479_RS03925	COG1263	PTS System
CG479_RS03975	COG1522	sequence-specific DNA binding
CG479_RS03990	COG0531	amino acid
CG479_RS04000	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS04010	COG1132	(ABC) transporter
CG479_RS04015	COG1132	(ABC) transporter
CG479_RS04025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG479_RS04030	COG0765	amino acid transport
CG479_RS04035	COG1126	abc transporter atp-binding protein
CG479_RS04050	COG0189	ligase activity
CG479_RS04055	COG4399	Belongs to the UPF0754 family
CG479_RS04060	COG3679	Belongs to the UPF0342 family
CG479_RS04065	COG4585	Histidine kinase
CG479_RS04070	COG2197	response regulator
CG479_RS04105	COG2094	Belongs to the DNA glycosylase MPG family
CG479_RS04110	COG0561	phosphatase activity
CG479_RS04120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG479_RS04150	COG2244	polysaccharide biosynthetic process
CG479_RS04160	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG479_RS04180	COG1696	Membrane protein involved in D-alanine export
CG479_RS04195	COG1024	Enoyl-CoA hydratase
CG479_RS04205	COG1363	Peptidase, m42
CG479_RS04220	COG2239	Acts as a magnesium transporter
CG479_RS04225	COG0772	Belongs to the SEDS family
CG479_RS04230	COG1115	amino acid carrier protein
CG479_RS04330	COG0457	Tetratricopeptide repeat
CG479_RS04395	COG1061	Type III restriction enzyme res subunit
CG479_RS04405	COG3829	transcription factor binding
CG479_RS04410	COG4638	Rieske (2fe-2S)
CG479_RS04415	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS04420	COG0473	3-isopropylmalate dehydrogenase activity
CG479_RS04430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS04440	COG1064	alcohol dehydrogenase
CG479_RS04455	COG3246	L-lysine catabolic process to acetate
CG479_RS04500	COG4641	Protein conserved in bacteria
CG479_RS04515	COG3711	transcriptional antiterminator
CG479_RS04520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG479_RS04520	COG1263	PTS System
CG479_RS04520	COG2190	(PTS) system
CG479_RS04525	COG2723	6-phospho-beta-galactosidase activity
CG479_RS04535	COG2376	Dihydroxyacetone kinase
CG479_RS04570	COG0420	3'-5' exonuclease activity
CG479_RS04575	COG4717	serine-type aminopeptidase activity
CG479_RS04580	COG3481	metal-dependent phosphohydrolase, HD sub domain
CG479_RS04595	COG0577	efflux transmembrane transporter activity
CG479_RS04600	COG1136	(ABC) transporter
CG479_RS04610	COG5002	protein histidine kinase activity
CG479_RS04615	COG0745	RESPONSE REGULATOR receiver
CG479_RS04625	COG1316	TRANSCRIPTIONal
CG479_RS04640	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CG479_RS04645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG479_RS04650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG479_RS04655	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG479_RS04675	COG1846	Transcriptional regulator
CG479_RS04680	COG4980	gas vesicle protein
CG479_RS04690	COG0537	adenosine 5'-monophosphoramidase activity
CG479_RS04700	COG1131	(ABC) transporter
CG479_RS04705	COG4473	ABC transporter
CG479_RS04725	COG3402	PFAM membrane-flanked domain
CG479_RS04735	COG2329	Antibiotic biosynthesis monooxygenase
CG479_RS04740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG479_RS04745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG479_RS04750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CG479_RS04755	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CG479_RS04785	COG1309	transcriptional regulator
CG479_RS04795	COG1216	Glycosyl transferase, family 2
CG479_RS04795	COG0438	transferase activity, transferring glycosyl groups
CG479_RS04805	COG1609	Transcriptional regulator
CG479_RS04815	COG1234	tRNA 3'-trailer cleavage
CG479_RS04820	COG0095	Lipoate-protein ligase
CG479_RS04830	COG0318	PFAM AMP-dependent synthetase and ligase
CG479_RS04845	COG2205	protein histidine kinase activity
CG479_RS04850	COG0745	RESPONSE REGULATOR receiver
CG479_RS04870	COG0501	Belongs to the peptidase M48B family
CG479_RS04875	COG0840	transmembrane signaling receptor activity
CG479_RS04880	COG0697	spore germination
CG479_RS04895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CG479_RS04900	COG2224	Isocitrate lyase
CG479_RS04905	COG1278	Cold shock
CG479_RS04910	COG4903	ComK protein
CG479_RS04915	COG0398	Pfam SNARE associated Golgi protein
CG479_RS04925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CG479_RS04930	COG1074	ATP-dependent DNA helicase activity
CG479_RS04970	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG479_RS04990	COG0367	asparagine synthase
CG479_RS05000	COG0753	catalase activity
CG479_RS05010	COG0366	Alpha amylase catalytic
CG479_RS05010	COG1874	Beta-galactosidase
CG479_RS05015	COG1666	GTP binding
CG479_RS05020	COG2996	Protein conserved in bacteria
CG479_RS05035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS05050	COG0561	phosphatase activity
CG479_RS05070	COG2267	carboxylic ester hydrolase activity
CG479_RS05085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG479_RS05090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG479_RS05095	COG5504	Zn-dependent protease
CG479_RS05110	COG0180	Tryptophanyl-tRNA synthetase
CG479_RS05135	COG0601	transmembrane transport
CG479_RS05140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG479_RS05145	COG0444	Belongs to the ABC transporter superfamily
CG479_RS05150	COG4608	Belongs to the ABC transporter superfamily
CG479_RS05155	COG0534	Mate efflux family protein
CG479_RS05160	COG4166	transmembrane transport
CG479_RS05180	COG0861	Integral membrane protein TerC family
CG479_RS05200	COG1164	Oligoendopeptidase f
CG479_RS05210	COG2346	COG2346, Truncated hemoglobins
CG479_RS05215	COG4116	CYTH
CG479_RS05225	COG2357	RelA SpoT domain protein
CG479_RS05235	COG0564	pseudouridine synthase activity
CG479_RS05245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG479_RS05250	COG0772	Belongs to the SEDS family
CG479_RS05295	COG1216	Glycosyl transferase, family 2
CG479_RS05340	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG479_RS05355	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG479_RS05380	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CG479_RS05385	COG2382	esterase
CG479_RS05400	COG5492	domain, Protein
CG479_RS05405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS05420	COG1620	l-lactate permease
CG479_RS05425	COG5634	Uncharacterized conserved protein (DUF2278)
CG479_RS05465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG479_RS05470	COG0567	Dehydrogenase, E1 component
CG479_RS05480	COG0583	DNA-binding transcription factor activity
CG479_RS05485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG479_RS05490	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS05505	COG0196	riboflavin kinase activity
CG479_RS05510	COG3162	membrane
CG479_RS05515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS05520	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG479_RS05535	COG0457	Tetratricopeptide repeat
CG479_RS05625	COG0457	Tetratricopeptide repeat
CG479_RS05630	COG0582	viral genome integration into host DNA
CG479_RS05670	COG1686	Belongs to the peptidase S11 family
CG479_RS05675	COG0681	Belongs to the peptidase S26 family
CG479_RS05710	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS05720	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG479_RS05725	COG1177	transmembrane transport
CG479_RS05730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG479_RS05735	COG0671	phosphoesterase, PA-phosphatase related
CG479_RS05740	COG2409	Drug exporters of the RND superfamily
CG479_RS05750	COG0564	pseudouridine synthase activity
CG479_RS05760	COG2340	Cysteine-rich secretory protein family
CG479_RS05765	COG0247	lactate metabolic process
CG479_RS05770	COG0277	FAD linked oxidase domain protein
CG479_RS05775	COG3835	regulator
CG479_RS05785	COG0745	RESPONSE REGULATOR receiver
CG479_RS05790	COG5002	protein histidine kinase activity
CG479_RS05795	COG2186	Transcriptional regulator
CG479_RS05800	COG0247	lactate metabolic process
CG479_RS05805	COG1139	Iron-sulfur cluster binding protein
CG479_RS05810	COG1556	Lactate utilization protein
CG479_RS05815	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG479_RS05820	COG0584	glycerophosphoryl diester phosphodiesterase
CG479_RS05830	COG2267	carboxylic ester hydrolase activity
CG479_RS05835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG479_RS05855	COG2116	formate transmembrane transporter activity
CG479_RS05860	COG0861	Integral membrane protein TerC family
CG479_RS05865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG479_RS05875	COG2030	dehydratase
CG479_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS05900	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG479_RS05905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG479_RS05920	COG1840	ABC-type Fe3 transport system, periplasmic component
CG479_RS05925	COG3842	ATPase activity
CG479_RS05935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG479_RS05940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG479_RS05945	COG1349	DNA-binding transcription factor activity
CG479_RS05950	COG0235	Class ii aldolase
CG479_RS05960	COG2861	carbohydrate metabolic process
CG479_RS05970	COG3852	Histidine kinase
CG479_RS05975	COG1846	Transcriptional regulator
CG479_RS05995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG479_RS06000	COG0720	synthase
CG479_RS06010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG479_RS06015	COG4873	Protein conserved in bacteria
CG479_RS06025	COG0456	acetyltransferase
CG479_RS06045	COG1780	Probably involved in ribonucleotide reductase function
CG479_RS06065	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG479_RS06070	COG1725	Transcriptional regulator
CG479_RS06075	COG1131	(ABC) transporter
CG479_RS06085	COG1131	(ABC) transporter
CG479_RS06090	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG479_RS06105	COG1522	sequence-specific DNA binding
CG479_RS06120	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG479_RS06125	COG2070	2-Nitropropane dioxygenase
CG479_RS06130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CG479_RS06140	COG1696	Membrane protein involved in D-alanine export
CG479_RS06145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG479_RS06160	COG0716	FMN binding
CG479_RS06185	COG1368	sulfuric ester hydrolase activity
CG479_RS06195	COG3173	Aminoglycoside phosphotransferase
CG479_RS06205	COG5609	conserved protein (DUF2294)
CG479_RS06210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG479_RS06215	COG3002	Belongs to the UPF0753 family
CG479_RS06220	COG0288	reversible hydration of carbon dioxide
CG479_RS06225	COG0534	Mate efflux family protein
CG479_RS06240	COG1846	Transcriptional regulator
CG479_RS06250	COG1301	dicarboxylic acid transport
CG479_RS06255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG479_RS06265	COG3874	Sporulation protein YtfJ
CG479_RS06290	COG0028	Belongs to the TPP enzyme family
CG479_RS06295	COG0440	acetolactate synthase activity
CG479_RS06300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG479_RS06305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG479_RS06315	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG479_RS06320	COG0066	3-isopropylmalate dehydratase activity
CG479_RS06330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG479_RS06340	COG0131	Imidazoleglycerol-phosphate dehydratase
CG479_RS06345	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG479_RS06350	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG479_RS06355	COG0107	imidazoleglycerol-phosphate synthase activity
CG479_RS06360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG479_RS06365	COG0140	phosphoribosyl-ATP diphosphatase activity
CG479_RS06380	COG1183	phosphatidylcholine synthase activity
CG479_RS06385	COG1368	sulfuric ester hydrolase activity
CG479_RS06395	COG0019	diaminopimelate decarboxylase activity
CG479_RS06405	COG0175	sulfate reduction
CG479_RS06410	COG2046	Belongs to the sulfate adenylyltransferase family
CG479_RS06415	COG0529	Catalyzes the synthesis of activated sulfate
CG479_RS06420	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG479_RS06440	COG1648	precorrin-2 dehydrogenase activity
CG479_RS06440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG479_RS06445	COG0733	neurotransmitter:sodium symporter activity
CG479_RS06460	COG3557	Belongs to the UPF0374 family
CG479_RS06465	COG1757	Na H antiporter
CG479_RS06480	COG4758	membrane
CG479_RS06485	COG4585	Histidine kinase
CG479_RS06490	COG2197	response regulator
CG479_RS06495	COG1114	Component of the transport system for branched-chain amino acids
CG479_RS06500	COG1525	nuclease
CG479_RS06500	COG4085	toxin activity
CG479_RS06500	COG0737	Belongs to the 5'-nucleotidase family
CG479_RS06530	COG3711	transcriptional antiterminator
CG479_RS06530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG479_RS06535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG479_RS06535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG479_RS06535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG479_RS06540	COG1482	cell wall glycoprotein biosynthetic process
CG479_RS06550	COG2801	Transposase and inactivated derivatives
CG479_RS06570	COG0730	response to heat
CG479_RS06575	COG0306	phosphate transporter
CG479_RS06580	COG1392	Phosphate transport regulator
CG479_RS06585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG479_RS06595	COG3852	Histidine kinase
CG479_RS06600	COG1801	Protein of unknown function DUF72
CG479_RS06610	COG0582	viral genome integration into host DNA
CG479_RS06615	COG5002	protein histidine kinase activity
CG479_RS06620	COG0813	purine-nucleoside phosphorylase activity
CG479_RS06630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CG479_RS06630	COG0392	lysyltransferase activity
CG479_RS06645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG479_RS06650	COG1686	Belongs to the peptidase S11 family
CG479_RS06655	COG2715	membrane protein required for spore maturation
CG479_RS06660	COG0700	Nucleoside recognition
CG479_RS06665	COG1187	pseudouridine synthase activity
CG479_RS06675	COG1333	cytochrome c biogenesis protein
CG479_RS06680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG479_RS06685	COG0745	RESPONSE REGULATOR receiver
CG479_RS06690	COG5002	protein histidine kinase activity
CG479_RS06695	COG2096	Adenosyltransferase
CG479_RS06710	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CG479_RS06715	COG1141	Ferredoxin
CG479_RS06725	COG0514	ATP-dependent DNA helicase (RecQ)
CG479_RS06730	COG1266	CAAX protease self-immunity
CG479_RS06740	COG1408	metallophosphoesterase
CG479_RS06755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG479_RS06770	COG0492	ferredoxin-NADP+ reductase activity
CG479_RS06780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG479_RS06790	COG1304	FMN binding
CG479_RS06825	COG1160	GTP binding
CG479_RS06830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG479_RS06850	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG479_RS06860	COG0302	gtp cyclohydrolase
CG479_RS06865	COG0142	geranyltranstransferase activity
CG479_RS06870	COG2226	methyltransferase
CG479_RS06875	COG0142	geranyltranstransferase activity
CG479_RS06885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG479_RS06890	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG479_RS06895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG479_RS06900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG479_RS06905	COG0457	Tetratricopeptide repeat
CG479_RS06910	COG5582	Belongs to the UPF0302 family
CG479_RS06925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG479_RS06935	COG4347	Protein of unknown function (DUF1405)
CG479_RS06950	COG2738	Putative neutral zinc metallopeptidase
CG479_RS06960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS06965	COG1694	Mazg nucleotide pyrophosphohydrolase
CG479_RS06970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG479_RS06975	COG1803	Methylglyoxal synthase
CG479_RS06980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG479_RS06985	COG0438	transferase activity, transferring glycosyl groups
CG479_RS06990	COG0617	tRNA 3'-terminal CCA addition
CG479_RS07005	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG479_RS07010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG479_RS07015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG479_RS07020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG479_RS07020	COG1199	ATP-dependent helicase activity
CG479_RS07040	COG3935	DnaD domain protein
CG479_RS07045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG479_RS07055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG479_RS07055	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG479_RS07060	COG3331	DNA recombination
CG479_RS07095	COG4474	Belongs to the UPF0398 family
CG479_RS07100	COG3599	regulation of cell shape
CG479_RS07110	COG0116	Belongs to the methyltransferase superfamily
CG479_RS07115	COG4974	Belongs to the 'phage' integrase family
CG479_RS07200	COG1199	ATP-dependent helicase activity
CG479_RS07205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CG479_RS07215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG479_RS07220	COG2233	PERMEase
CG479_RS07225	COG2311	Membrane
CG479_RS07230	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG479_RS07240	COG0456	acetyltransferase
CG479_RS07280	COG3766	membrane
CG479_RS07290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG479_RS07295	COG1733	regulation of RNA biosynthetic process
CG479_RS07315	COG0328	RNA-DNA hybrid ribonuclease activity
CG479_RS07345	COG1278	Cold shock
CG479_RS07355	COG3162	membrane
CG479_RS07360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS07365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG479_RS07370	COG0475	glutathione-regulated potassium exporter activity
CG479_RS07375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG479_RS07380	COG2323	membrane
CG479_RS07385	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG479_RS07410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG479_RS07420	COG2201	protein-glutamate methylesterase activity
CG479_RS07425	COG2198	Histidine kinase
CG479_RS07425	COG0643	Histidine kinase
CG479_RS07430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG479_RS07430	COG1776	CheC inhibitor of MCP methylation
CG479_RS07445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG479_RS07455	COG1728	Protein conserved in bacteria
CG479_RS07465	COG1256	bacterial-type flagellum assembly
CG479_RS07470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG479_RS07490	COG1815	bacterial-type flagellum-dependent cell motility
CG479_RS07495	COG1558	bacterial-type flagellum-dependent cell motility
CG479_RS07510	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG479_RS07520	COG1157	protein secretion by the type III secretion system
CG479_RS07555	COG0835	chemotaxis
CG479_RS07555	COG0784	Response regulator, receiver
CG479_RS07565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG479_RS07570	COG0463	Glycosyl transferase, family 2
CG479_RS07570	COG0457	Tetratricopeptide repeat
CG479_RS07585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG479_RS07590	COG0741	lytic transglycosylase activity
CG479_RS07600	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG479_RS07605	COG1776	CheC inhibitor of MCP methylation
CG479_RS07605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG479_RS07615	COG1338	Plays a role in the flagellum-specific transport system
CG479_RS07620	COG1987	bacterial-type flagellum assembly
CG479_RS07630	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG479_RS07635	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG479_RS07640	COG1419	protein localization to endoplasmic reticulum
CG479_RS07645	COG4786	Flagellar basal body rod
CG479_RS07650	COG0577	efflux transmembrane transporter activity
CG479_RS07650	COG1136	(ABC) transporter
CG479_RS07680	COG1309	transcriptional regulator
CG479_RS07700	COG2814	Major facilitator Superfamily
CG479_RS07745	COG0367	asparagine synthase
CG479_RS07765	COG1802	Transcriptional regulator
CG479_RS07770	COG0697	spore germination
CG479_RS07785	COG1757	Na H antiporter
CG479_RS07815	COG0534	Mate efflux family protein
CG479_RS07820	COG3340	Belongs to the peptidase S51 family
CG479_RS07825	COG2733	membrane
CG479_RS07835	COG1280	lysine exporter protein (LysE YggA)
CG479_RS07840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG479_RS07855	COG2502	aspartate--ammonia ligase
CG479_RS07860	COG1309	transcriptional regulator
CG479_RS07865	COG0109	protoheme IX farnesyltransferase activity
CG479_RS07895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG479_RS07900	COG0488	(ABC) transporter
CG479_RS07905	COG4166	transmembrane transport
CG479_RS07910	COG2223	nitrite transmembrane transporter activity
CG479_RS07915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG479_RS07920	COG2244	polysaccharide biosynthetic process
CG479_RS07925	COG0733	neurotransmitter:sodium symporter activity
CG479_RS07930	COG5566	PFAM Mor transcription activator
CG479_RS07940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG479_RS07945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG479_RS07955	COG0129	dihydroxy-acid dehydratase activity
CG479_RS07960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG479_RS07990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG479_RS07995	COG2814	Major facilitator Superfamily
CG479_RS08000	COG3384	dioxygenase
CG479_RS08020	COG0402	S-adenosylhomocysteine deaminase activity
CG479_RS08025	COG4166	transmembrane transport
CG479_RS08035	COG1914	H( )-stimulated, divalent metal cation uptake system
CG479_RS08040	COG1054	Belongs to the UPF0176 family
CG479_RS08050	COG0083	homoserine kinase activity
CG479_RS08060	COG2390	Transcriptional regulator
CG479_RS08065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG479_RS08080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG479_RS08090	COG1510	regulation of RNA biosynthetic process
CG479_RS08095	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS08100	COG1454	alcohol dehydrogenase
CG479_RS08120	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG479_RS08130	COG0628	permease
CG479_RS08145	COG0523	cobalamin synthesis protein
CG479_RS08170	COG1686	Belongs to the peptidase S11 family
CG479_RS08185	COG0791	NLP P60 protein
CG479_RS08185	COG1388	LysM domain
CG479_RS08190	COG0300	oxidoreductase activity
CG479_RS08200	COG0460	homoserine dehydrogenase
CG479_RS08210	COG0083	homoserine kinase activity
CG479_RS08215	COG1316	TRANSCRIPTIONal
CG479_RS08230	COG1285	pathogenesis
CG479_RS08235	COG1247	-acetyltransferase
CG479_RS08270	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CG479_RS08275	COG0577	efflux transmembrane transporter activity
CG479_RS08280	COG2409	Drug exporters of the RND superfamily
CG479_RS08285	COG1404	Belongs to the peptidase S8 family
CG479_RS08300	COG0840	transmembrane signaling receptor activity
CG479_RS08315	COG3949	Membrane
CG479_RS08320	COG0783	Belongs to the Dps family
CG479_RS08340	COG0523	cobalamin synthesis protein
CG479_RS08350	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG479_RS08365	COG1902	pentaerythritol trinitrate reductase activity
CG479_RS08370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG479_RS08380	COG4166	transmembrane transport
CG479_RS08385	COG0346	lactoylglutathione lyase activity
CG479_RS08395	COG5337	Spore coat protein CotH
CG479_RS08400	COG1051	belongs to the nudix hydrolase family
CG479_RS08405	COG0586	Pfam SNARE associated Golgi protein
CG479_RS08410	COG2244	polysaccharide biosynthetic process
CG479_RS08420	COG0701	Predicted permease
CG479_RS08425	COG3689	TIGRFAM TIGR03943 family protein
CG479_RS08430	COG1607	acyl-coa hydrolase
CG479_RS08440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG479_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS08460	COG2839	Protein conserved in bacteria
CG479_RS08465	COG1253	flavin adenine dinucleotide binding
CG479_RS08480	COG1114	Component of the transport system for branched-chain amino acids
CG479_RS08500	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG479_RS08510	COG1876	peptidase activity
CG479_RS08540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG479_RS08545	COG1819	glycosyl
CG479_RS08550	COG1819	glycosyl
CG479_RS08555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG479_RS08600	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG479_RS08660	COG3874	Sporulation protein YtfJ
CG479_RS08685	COG2226	methyltransferase
CG479_RS08710	COG0386	Belongs to the glutathione peroxidase family
CG479_RS08740	COG0640	Transcriptional regulator
CG479_RS08745	COG0798	PFAM Bile acid sodium symporter
CG479_RS08750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG479_RS08795	COG1418	mRNA catabolic process
CG479_RS08800	COG0488	(ABC) transporter
CG479_RS08810	COG0629	single-stranded DNA binding
CG479_RS08815	COG1413	lyase activity
CG479_RS08830	COG2521	methyltransferase
CG479_RS08830	COG2136	Putative SAM-dependent methyltransferase
CG479_RS08835	COG0018	arginyl-trna synthetase
CG479_RS08845	COG0733	neurotransmitter:sodium symporter activity
CG479_RS08850	COG0596	Alpha beta hydrolase
CG479_RS08870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG479_RS08875	COG0477	Major facilitator Superfamily
CG479_RS08895	COG1454	alcohol dehydrogenase
CG479_RS08900	COG2610	gluconate transmembrane transporter activity
CG479_RS08910	COG0456	acetyltransferase
CG479_RS08915	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG479_RS08925	COG1131	(ABC) transporter
CG479_RS08930	COG4473	ABC transporter
CG479_RS08945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG479_RS08950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG479_RS08960	COG0768	penicillin binding
CG479_RS08970	COG0204	Acyl-transferase
CG479_RS08980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG479_RS08985	COG0805	protein transport
CG479_RS08995	COG1307	EDD domain protein, DegV family
CG479_RS09005	COG1999	signal sequence binding
CG479_RS09010	COG0071	Belongs to the small heat shock protein (HSP20) family
CG479_RS09015	COG0367	asparagine synthase
CG479_RS09030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG479_RS09060	COG0071	Belongs to the small heat shock protein (HSP20) family
CG479_RS09070	COG1737	Transcriptional regulator
CG479_RS09075	COG1070	Carbohydrate kinase
CG479_RS09085	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CG479_RS09140	COG1151	hydroxylamine reductase activity
CG479_RS09150	COG1253	flavin adenine dinucleotide binding
CG479_RS09155	COG5506	Protein of unknown function (DUF1694)
CG479_RS09175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG479_RS09180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CG479_RS09185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG479_RS09190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG479_RS09195	COG0456	acetyltransferase
CG479_RS09200	COG3829	transcription factor binding
CG479_RS09210	COG1509	lysine 2,3-aminomutase activity
CG479_RS09220	COG4479	Belongs to the UPF0346 family
CG479_RS09225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG479_RS09255	COG1357	PFAM Pentapeptide repeats (8 copies)
CG479_RS09255	COG0515	serine threonine protein kinase
CG479_RS09260	COG0671	phosphoesterase, PA-phosphatase related
CG479_RS09265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG479_RS09270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG479_RS09320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CG479_RS09330	COG0726	polysaccharide deacetylase
CG479_RS09335	COG1408	metallophosphoesterase
CG479_RS09340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG479_RS09345	COG2323	membrane
CG479_RS09350	COG0671	phosphoesterase, PA-phosphatase related
CG479_RS09360	COG1280	lysine exporter protein (LysE YggA)
CG479_RS09365	COG3403	YqcI/YcgG family
CG479_RS09395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG479_RS09395	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG479_RS09405	COG0372	Belongs to the citrate synthase family
CG479_RS09410	COG2079	MmgE PrpD family protein
CG479_RS09415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CG479_RS09420	COG1960	acyl-CoA dehydrogenase activity
CG479_RS09425	COG2084	Dehydrogenase
CG479_RS09430	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS09440	COG1280	lysine exporter protein (LysE YggA)
CG479_RS09465	COG0420	3'-5' exonuclease activity
CG479_RS09470	COG0419	ATPase involved in DNA repair
CG479_RS09475	COG3104	oligopeptide transport
CG479_RS09505	COG1131	(ABC) transporter
CG479_RS09525	COG1131	(ABC) transporter
CG479_RS09530	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG479_RS09550	COG1942	4-Oxalocrotonate Tautomerase
CG479_RS09565	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS09570	COG1169	isochorismate synthase
CG479_RS09575	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG479_RS09580	COG1535	isochorismatase
CG479_RS09580	COG3433	isochorismatase activity
CG479_RS09585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG479_RS09590	COG3251	PFAM MbtH domain protein
CG479_RS09595	COG2814	Major facilitator Superfamily
CG479_RS09610	COG0776	regulation of translation
CG479_RS09625	COG2329	Antibiotic biosynthesis monooxygenase
CG479_RS09630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG479_RS09670	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CG479_RS09675	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CG479_RS09680	COG0667	Aldo Keto reductase
CG479_RS09700	COG0010	Belongs to the arginase family
CG479_RS09710	COG1132	(ABC) transporter
CG479_RS09715	COG1132	(ABC) transporter
CG479_RS09745	COG1649	PFAM Uncharacterised BCR, COG1649
CG479_RS09765	COG2971	BadF BadG BcrA BcrD
CG479_RS09785	COG0588	phosphoglycerate mutase activity
CG479_RS09820	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG479_RS09830	COG1960	acyl-CoA dehydrogenase activity
CG479_RS09835	COG0439	Biotin carboxylase
CG479_RS09840	COG0511	ligase activity, forming carbon-carbon bonds
CG479_RS09845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG479_RS09850	COG1024	Enoyl-CoA hydratase
CG479_RS09855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG479_RS09860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG479_RS09870	COG1216	Glycosyl transferase, family 2
CG479_RS09875	COG0640	Transcriptional regulator
CG479_RS09890	COG1686	Belongs to the peptidase S11 family
CG479_RS09895	COG5002	protein histidine kinase activity
CG479_RS09930	COG0789	Transcriptional regulator
CG479_RS09955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG479_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS09985	COG0475	glutathione-regulated potassium exporter activity
CG479_RS09990	COG0475	glutathione-regulated potassium exporter activity
CG479_RS10010	COG1309	transcriptional regulator
CG479_RS10025	COG2002	toxin-antitoxin pair type II binding
CG479_RS10045	COG0693	protein deglycase activity
CG479_RS10050	COG0201	protein transport
CG479_RS10075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG479_RS10080	COG0322	excinuclease ABC activity
CG479_RS10090	COG4667	esterase of the alpha-beta hydrolase superfamily
CG479_RS10135	COG2223	nitrite transmembrane transporter activity
CG479_RS10180	COG1216	Glycosyl transferase, family 2
CG479_RS10195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG479_RS10200	COG1279	arginine transmembrane transporter activity
CG479_RS10235	COG1794	racemase activity, acting on amino acids and derivatives
CG479_RS10245	COG2828	Protein conserved in bacteria
CG479_RS10250	COG5002	protein histidine kinase activity
CG479_RS10255	COG0561	phosphatase activity
CG479_RS10275	COG2124	cytochrome p450
CG479_RS10310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG479_RS10315	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS10320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG479_RS10330	COG2959	enzyme of heme biosynthesis
CG479_RS10360	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG479_RS10365	COG3844	kynureninase activity
CG479_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS10385	COG4176	ABC-type proline glycine betaine transport system permease component
CG479_RS10390	COG0517	IMP dehydrogenase activity
CG479_RS10390	COG4175	Glycine betaine
CG479_RS10420	COG2153	protein acetylation
CG479_RS10450	COG0514	ATP-dependent DNA helicase (RecQ)
CG479_RS10470	COG4637	Psort location Cytoplasmic, score
CG479_RS10475	COG1227	inorganic diphosphatase activity
CG479_RS10485	COG3397	chitin binding
CG479_RS10525	COG4166	transmembrane transport
CG479_RS10535	COG4948	Mandelate Racemase Muconate Lactonizing
CG479_RS10565	COG1131	(ABC) transporter
CG479_RS10570	COG1994	Peptidase M50
CG479_RS10605	COG1307	EDD domain protein, DegV family
CG479_RS10665	COG5444	nuclease activity
CG479_RS10765	COG2261	transglycosylase associated protein
CG479_RS10795	COG0436	Aminotransferase
CG479_RS10810	COG3973	AAA domain
CG479_RS10820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG479_RS10845	COG0628	permease
CG479_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG479_RS10865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG479_RS10870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG479_RS10885	COG2746	aminoglycoside 3-N-acetyltransferase activity
CG479_RS10900	COG0454	-acetyltransferase
CG479_RS10900	COG0456	acetyltransferase
CG479_RS10925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG479_RS10930	COG1368	sulfuric ester hydrolase activity
CG479_RS10935	COG0488	(ABC) transporter
CG479_RS10940	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG479_RS10940	COG1605	Chorismate mutase
CG479_RS10960	COG0346	lactoylglutathione lyase activity
CG479_RS10970	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG479_RS11010	COG2329	Antibiotic biosynthesis monooxygenase
CG479_RS11025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG479_RS11050	COG0494	nUDIX hydrolase
CG479_RS11065	COG0456	acetyltransferase
CG479_RS11085	COG0697	spore germination
CG479_RS11090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG479_RS11100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG479_RS11115	COG0730	response to heat
CG479_RS11125	COG0833	amino acid
CG479_RS11150	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CG479_RS11165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG479_RS11170	COG1984	allophanate hydrolase subunit 2
CG479_RS11175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG479_RS11180	COG1414	Transcriptional regulator
CG479_RS11195	COG1960	acyl-CoA dehydrogenase activity
CG479_RS11210	COG3314	Sporulation integral membrane protein YlbJ
CG479_RS11225	COG0346	lactoylglutathione lyase activity
CG479_RS11235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG479_RS11240	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG479_RS11245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG479_RS11250	COG0438	transferase activity, transferring glycosyl groups
CG479_RS11265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG479_RS11270	COG0438	transferase activity, transferring glycosyl groups
CG479_RS11275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG479_RS11290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG479_RS11310	COG4851	CamS sex pheromone cAM373 precursor
CG479_RS11380	COG0477	Major facilitator Superfamily
CG479_RS11395	COG1846	Transcriptional regulator
CG479_RS11400	COG2814	Major facilitator Superfamily
CG479_RS11410	COG2031	fatty acid transporter
CG479_RS11440	COG1122	ATPase activity
CG479_RS11465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG479_RS11480	COG1131	(ABC) transporter
CG479_RS11500	COG2365	Tyrosine phosphatase family
CG479_RS11540	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CG479_RS11545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS11550	COG0579	oxidoreductase
CG479_RS11555	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CG479_RS11565	COG1253	flavin adenine dinucleotide binding
CG479_RS11570	COG0789	Transcriptional regulator
CG479_RS11575	COG3813	Protein conserved in bacteria
CG479_RS11590	COG0384	phenazine biosynthesis protein PhzF
CG479_RS11650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG479_RS11690	COG0577	efflux transmembrane transporter activity
CG479_RS11690	COG1136	(ABC) transporter
CG479_RS11795	COG2076	Multidrug Resistance protein
CG479_RS11810	COG2072	flavoprotein involved in K transport
CG479_RS11840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG479_RS11845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG479_RS11855	COG1193	negative regulation of DNA recombination
CG479_RS11860	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CG479_RS11865	COG1164	Oligoendopeptidase f
CG479_RS11885	COG0584	glycerophosphoryl diester phosphodiesterase
CG479_RS11890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG479_RS11920	COG3397	chitin binding
CG479_RS11930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG479_RS11935	COG0277	FAD linked oxidase domain protein
CG479_RS11940	COG1285	pathogenesis
CG479_RS11945	COG2720	vancomycin resistance protein
CG479_RS11965	COG1278	Cold shock
CG479_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS11980	COG0165	Argininosuccinate lyase
CG479_RS11995	COG4145	pantothenate transmembrane transporter activity
CG479_RS12000	COG3924	membrane
CG479_RS12005	COG1012	belongs to the aldehyde dehydrogenase family
CG479_RS12015	COG1657	PFAM Prenyltransferase squalene oxidase
CG479_RS12020	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CG479_RS12025	COG2962	Rard protein
CG479_RS12060	COG2226	methyltransferase
CG479_RS12065	COG4166	transmembrane transport
CG479_RS12070	COG4166	transmembrane transport
CG479_RS12075	COG1301	dicarboxylic acid transport
CG479_RS12085	COG0673	inositol 2-dehydrogenase activity
CG479_RS12090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG479_RS12095	COG0187	DNA topoisomerase II activity
CG479_RS12105	COG1832	CoA-binding protein
CG479_RS12110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG479_RS12115	COG0745	RESPONSE REGULATOR receiver
CG479_RS12130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG479_RS12135	COG4841	protein insertion into membrane
CG479_RS12140	COG0824	Thioesterase
CG479_RS12170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG479_RS12175	COG3655	Transcriptional regulator
CG479_RS12195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG479_RS12235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG479_RS12240	COG0318	PFAM AMP-dependent synthetase and ligase
CG479_RS12350	COG2826	transposase and inactivated derivatives, IS30 family
CG479_RS12365	COG0534	Mate efflux family protein
CG479_RS12395	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG479_RS12405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS12415	COG5002	protein histidine kinase activity
CG479_RS12420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG479_RS12425	COG0010	Belongs to the arginase family
CG479_RS12430	COG1228	amidohydrolase
CG479_RS12435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CG479_RS12440	COG2986	histidine ammonia-lyase
CG479_RS12460	COG4846	Membrane protein involved in cytochrome C biogenesis
CG479_RS12465	COG0785	Cytochrome C biogenesis protein
CG479_RS12480	COG0583	DNA-binding transcription factor activity
CG479_RS12485	COG1380	Effector of murein hydrolase LrgA
CG479_RS12490	COG1346	cytolysis
CG479_RS12495	COG4187	Peptidase family M20/M25/M40
CG479_RS12505	COG0833	amino acid
CG479_RS12515	COG0730	response to heat
CG479_RS12525	COG3409	Peptidoglycan-binding domain 1 protein
CG479_RS12525	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG479_RS12540	COG1132	(ABC) transporter
CG479_RS12545	COG1132	(ABC) transporter
CG479_RS12550	COG3763	UPF0154 protein
CG479_RS12565	COG3639	organic phosphonate transmembrane transporter activity
CG479_RS12570	COG3639	organic phosphonate transmembrane transporter activity
CG479_RS12585	COG0737	Belongs to the 5'-nucleotidase family
CG479_RS12590	COG4224	UPF0291 protein
CG479_RS12595	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG479_RS12600	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG479_RS12615	COG1695	Transcriptional regulator
CG479_RS12655	COG3328	transposase activity
CG479_RS12660	COG3328	transposase activity
CG479_RS12665	COG3328	transposase activity
CG479_RS12680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG479_RS12705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG479_RS12725	COG0730	response to heat
CG479_RS12780	COG0174	glutamine synthetase
CG479_RS12785	COG0789	Transcriptional regulator
CG479_RS12790	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CG479_RS12795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG479_RS12800	COG2860	membrane
CG479_RS12805	COG0464	growth
CG479_RS12820	COG1923	regulation of RNA biosynthetic process
CG479_RS12825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG479_RS12835	COG3584	3D domain protein
CG479_RS12835	COG1388	LysM domain
CG479_RS12840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG479_RS12840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG479_RS12840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG479_RS12845	COG1105	Belongs to the carbohydrate kinase PfkB family
CG479_RS12850	COG1349	DNA-binding transcription factor activity
CG479_RS12855	COG2322	membrane
CG479_RS12880	COG2116	formate transmembrane transporter activity
CG479_RS12890	COG1937	Protein conserved in bacteria
CG479_RS12895	COG2819	hydrolase of the alpha beta superfamily
CG479_RS12900	COG1120	ATPase activity
CG479_RS12905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS12910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS12915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG479_RS12920	COG2706	6-phosphogluconolactonase activity
CG479_RS12925	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG479_RS12935	COG0346	lactoylglutathione lyase activity
CG479_RS12950	COG1113	amino acid transport
CG479_RS12975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG479_RS12980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG479_RS12990	COG4550	Control of competence regulator ComK, YlbF/YmcA
CG479_RS12995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG479_RS13000	COG1013	pyruvate-flavodoxin oxidoreductase activity
CG479_RS13005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CG479_RS13005	COG0674	pyruvate-flavodoxin oxidoreductase activity
CG479_RS13015	COG2359	stage V sporulation protein S
CG479_RS13020	COG1692	metallophosphoesterase
CG479_RS13025	COG1418	mRNA catabolic process
CG479_RS13030	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG479_RS13035	COG1058	Belongs to the CinA family
CG479_RS13035	COG1546	Belongs to the CinA family
CG479_RS13040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG479_RS13045	COG1426	Protein conserved in bacteria
CG479_RS13060	COG0300	oxidoreductase activity
CG479_RS13065	COG0612	Peptidase, M16
CG479_RS13070	COG0612	Peptidase, M16
CG479_RS13075	COG1079	Belongs to the binding-protein-dependent transport system permease family
CG479_RS13080	COG4603	Belongs to the binding-protein-dependent transport system permease family
CG479_RS13085	COG3845	ABC transporter
CG479_RS13090	COG1744	ABC transporter substrate-binding protein PnrA-like
CG479_RS13095	COG2188	Transcriptional regulator
CG479_RS13100	COG1674	ftsk spoiiie
CG479_RS13115	COG0740	serine-type endopeptidase activity
CG479_RS13120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG479_RS13135	COG0527	aspartate kinase activity
CG479_RS13140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG479_RS13145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG479_RS13150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG479_RS13155	COG1873	PFAM PRC-barrel domain
CG479_RS13160	COG0612	Peptidase, M16
CG479_RS13165	COG0726	polysaccharide deacetylase
CG479_RS13170	COG1185	polyribonucleotide nucleotidyltransferase activity
CG479_RS13180	COG0196	riboflavin kinase activity
CG479_RS13185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG479_RS13190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG479_RS13195	COG1550	Protein conserved in bacteria
CG479_RS13200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG479_RS13205	COG1358	cellular component organization or biogenesis
CG479_RS13210	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CG479_RS13215	COG0195	Participates in both transcription termination and antitermination
CG479_RS13220	COG0779	Required for maturation of 30S ribosomal subunits
CG479_RS13230	COG0442	prolyl-tRNA aminoacylation
CG479_RS13235	COG0750	zinc metalloprotease
CG479_RS13245	COG4589	Belongs to the CDS family
CG479_RS13255	COG0233	cytoplasmic translational termination
CG479_RS13260	COG0528	UMP kinase activity
CG479_RS13265	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG479_RS13270	COG0052	Belongs to the universal ribosomal protein uS2 family
CG479_RS13275	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CG479_RS13280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG479_RS13285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG479_RS13290	COG4974	Belongs to the 'phage' integrase family
CG479_RS13295	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CG479_RS13300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG479_RS13305	COG0758	DNA mediated transformation
CG479_RS13310	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG479_RS13315	COG0045	succinate-CoA ligase (ADP-forming) activity
CG479_RS13320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG479_RS13335	COG0335	large ribosomal subunit rRNA binding
CG479_RS13340	COG0336	Belongs to the RNA methyltransferase TrmD family
CG479_RS13345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG479_RS13350	COG1837	Belongs to the UPF0109 family
CG479_RS13355	COG0228	four-way junction DNA binding
CG479_RS13360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG479_RS13365	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CG479_RS13370	COG0552	protein localization to endoplasmic reticulum
CG479_RS13375	COG1196	nuclear chromosome segregation
CG479_RS13380	COG0571	ribonuclease III activity
CG479_RS13385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG479_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS13395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG479_RS13400	COG0416	fatty acid biosynthetic process
CG479_RS13405	COG1349	DNA-binding transcription factor activity
CG479_RS13405	COG2050	protein possibly involved in aromatic compounds catabolism
CG479_RS13410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG479_RS13415	COG1461	Dihydroxyacetone kinase
CG479_RS13420	COG1302	Protein conserved in bacteria
CG479_RS13425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG479_RS13435	COG1564	THIamine pyrophosphokinase
CG479_RS13440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG479_RS13445	COG1162	GTPase activity
CG479_RS13450	COG0515	serine threonine protein kinase
CG479_RS13450	COG2815	serine threonine protein kinase
CG479_RS13455	COG0631	protein serine/threonine phosphatase activity
CG479_RS13460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG479_RS13465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG479_RS13465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG479_RS13470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG479_RS13475	COG0242	peptide deformylase activity
CG479_RS13480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG479_RS13490	COG1758	RNA polymerase activity
CG479_RS13505	COG1561	YicC-like family, N-terminal region
CG479_RS13510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG479_RS13535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG479_RS13540	COG0284	orotidine-5'-phosphate decarboxylase activity
CG479_RS13545	COG0167	dihydroorotate dehydrogenase activity
CG479_RS13550	COG0543	2 iron, 2 sulfur cluster binding
CG479_RS13555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG479_RS13565	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CG479_RS13570	COG0540	Belongs to the ATCase OTCase family
CG479_RS13580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CG479_RS13590	COG0564	pseudouridine synthase activity
CG479_RS13595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG479_RS13605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG479_RS13610	COG3599	regulation of cell shape
CG479_RS13615	COG2302	S4 RNA-binding domain
CG479_RS13620	COG0762	integral membrane protein
CG479_RS13625	COG1799	cell septum assembly
CG479_RS13630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG479_RS13640	COG1873	PFAM PRC-barrel domain
CG479_RS13645	COG1191	sigma factor activity
CG479_RS13650	COG1191	sigma factor activity
CG479_RS13660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG479_RS13665	COG0849	cell division
CG479_RS13670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG479_RS13680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG479_RS13685	COG0772	Belongs to the SEDS family
CG479_RS13690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG479_RS13695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG479_RS13700	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG479_RS13705	COG0768	penicillin binding
CG479_RS13710	COG0768	penicillin binding
CG479_RS13715	COG4839	cell division protein FtsL
CG479_RS13720	COG0275	rRNA processing
CG479_RS13725	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CG479_RS13730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CG479_RS13735	COG0454	-acetyltransferase
CG479_RS13745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CG479_RS13750	COG1399	metal-binding, possibly nucleic acid-binding protein
CG479_RS13860	COG4626	Terminase
CG479_RS13860	COG1802	Transcriptional regulator
CG479_RS13950	COG0756	dUTP diphosphatase activity
CG479_RS13980	COG3723	Recombinational DNA repair protein, rece pathway
CG479_RS13990	COG5377	YqaJ viral recombinase family
CG479_RS14030	COG0582	viral genome integration into host DNA
CG479_RS14035	COG1323	Belongs to the UPF0348 family
CG479_RS14040	COG3480	Lon protease (S16) C-terminal proteolytic domain
CG479_RS14045	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG479_RS14050	COG3314	Sporulation integral membrane protein YlbJ
CG479_RS14055	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG479_RS14060	COG0742	ribosomal rna small subunit methyltransferase
CG479_RS14070	COG4471	UPF0298 protein
CG479_RS14075	COG3679	Belongs to the UPF0342 family
CG479_RS14080	COG0406	alpha-ribazole phosphatase activity
CG479_RS14095	COG2340	Cysteine-rich secretory protein family
CG479_RS14105	COG3336	cytochrome c oxidase
CG479_RS14130	COG0109	protoheme IX farnesyltransferase activity
CG479_RS14135	COG1612	heme a metabolic process
CG479_RS14140	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CG479_RS14150	COG0772	Belongs to the SEDS family
CG479_RS14155	COG4838	Belongs to the UPF0358 family
CG479_RS14160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG479_RS14165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG479_RS14175	COG4896	Protein conserved in bacteria
CG479_RS14190	COG1217	gtp-binding protein TYPA
CG479_RS14200	COG0483	inositol monophosphate 1-phosphatase activity
CG479_RS14210	COG4493	Belongs to the UPF0637 family
CG479_RS14215	COG4476	Belongs to the UPF0223 family
CG479_RS14220	COG1982	Orn Lys Arg decarboxylase major
CG479_RS14260	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG479_RS14270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG479_RS14285	COG0561	phosphatase activity
CG479_RS14295	COG5503	Protein of unknown function (DUF1447)
CG479_RS14300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG479_RS14305	COG0569	domain protein
CG479_RS14315	COG1473	amidohydrolase
CG479_RS14320	COG2171	N-acyltransferase activity
CG479_RS14325	COG0583	DNA-binding transcription factor activity
CG479_RS14330	COG0517	IMP dehydrogenase activity
CG479_RS14340	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CG479_RS14355	COG4703	Protein of unknown function (DUF1797)
CG479_RS14370	COG2200	EAL domain
CG479_RS14375	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS14380	COG1408	metallophosphoesterase
CG479_RS14390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG479_RS14430	COG2814	Major facilitator Superfamily
CG479_RS14435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG479_RS14445	COG3209	COG3209 Rhs family protein
CG479_RS14455	COG2205	protein histidine kinase activity
CG479_RS14465	COG0436	Aminotransferase
CG479_RS14470	COG1609	Transcriptional regulator
CG479_RS14475	COG3833	ABC-type maltose transport systems, permease component
CG479_RS14480	COG1175	transmembrane transport
CG479_RS14485	COG2182	Extracellular solute-binding protein
CG479_RS14500	COG0366	Alpha amylase catalytic
CG479_RS14505	COG3842	ATPase activity
CG479_RS14535	COG0183	Belongs to the thiolase family
CG479_RS14565	COG1695	Transcriptional regulator
CG479_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS14580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CG479_RS14585	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CG479_RS14590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG479_RS14595	COG0436	Aminotransferase
CG479_RS14600	COG1850	ribulose-bisphosphate carboxylase activity
CG479_RS14605	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CG479_RS14610	COG0235	Class ii aldolase
CG479_RS14615	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CG479_RS14630	COG2084	Dehydrogenase
CG479_RS14640	COG2199	diguanylate cyclase activity
CG479_RS14645	COG0778	Nitroreductase
CG479_RS14670	COG1263	PTS System
CG479_RS14670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG479_RS14670	COG2190	(PTS) system
CG479_RS14675	COG3711	transcriptional antiterminator
CG479_RS14685	COG2188	Transcriptional regulator
CG479_RS14690	COG0363	glucosamine-6-phosphate deaminase activity
CG479_RS14705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG479_RS14710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG479_RS14720	COG1547	Domain of unknown function (DUF309)
CG479_RS14730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG479_RS14735	COG4086	secreted protein
CG479_RS14740	COG0561	phosphatase activity
CG479_RS14745	COG0697	spore germination
CG479_RS14760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG479_RS14785	COG0733	neurotransmitter:sodium symporter activity
CG479_RS14795	COG2172	sigma factor antagonist activity
CG479_RS14805	COG1686	Belongs to the peptidase S11 family
CG479_RS14815	COG1725	Transcriptional regulator
CG479_RS14820	COG1131	(ABC) transporter
CG479_RS14845	COG1846	Transcriptional regulator
CG479_RS14860	COG0598	Magnesium transport protein CorA
CG479_RS14890	COG4974	Belongs to the 'phage' integrase family
CG479_RS14900	COG0735	belongs to the Fur family
CG479_RS14905	COG1300	Membrane
CG479_RS14925	COG0667	Aldo Keto reductase
CG479_RS14930	COG0656	L-ascorbic acid biosynthetic process
CG479_RS14935	COG0456	acetyltransferase
CG479_RS14935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CG479_RS14945	COG4085	toxin activity
CG479_RS14945	COG1525	nuclease
CG479_RS14945	COG0737	Belongs to the 5'-nucleotidase family
CG479_RS14955	COG0596	Alpha beta hydrolase
CG479_RS14960	COG2056	Na+-H+ antiporter family
CG479_RS14965	COG1609	Transcriptional regulator
CG479_RS14970	COG0456	acetyltransferase
CG479_RS14975	COG1073	alpha beta
CG479_RS14990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG479_RS14990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG479_RS14995	COG0307	riboflavin synthase, alpha
CG479_RS15000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG479_RS15000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG479_RS15015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG479_RS15020	COG4106	trans-aconitate 2-methyltransferase activity
CG479_RS15025	COG0596	Alpha beta hydrolase
CG479_RS15030	COG0156	8-amino-7-oxononanoate synthase activity
CG479_RS15040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG479_RS15050	COG1757	Na H antiporter
CG479_RS15055	COG0737	Belongs to the 5'-nucleotidase family
CG479_RS15080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG479_RS15090	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG479_RS15100	COG0300	oxidoreductase activity
CG479_RS15105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG479_RS15110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG479_RS15115	COG1760	l-serine dehydratase
CG479_RS15120	COG1760	l-serine dehydratase
CG479_RS15130	COG1234	tRNA 3'-trailer cleavage
CG479_RS15155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG479_RS15170	COG1376	ErfK ybiS ycfS ynhG family protein
CG479_RS15175	COG4129	membrane
CG479_RS15180	COG1126	abc transporter atp-binding protein
CG479_RS15185	COG0765	amino acid transport
CG479_RS15190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG479_RS15205	COG2816	NAD+ diphosphatase activity
CG479_RS15210	COG0772	Belongs to the SEDS family
CG479_RS15220	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG479_RS15225	COG0022	dehydrogenase e1 component
CG479_RS15230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG479_RS15235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG479_RS15240	COG3426	butyrate kinase activity
CG479_RS15250	COG0280	phosphate acetyltransferase
CG479_RS15260	COG3829	transcription factor binding
CG479_RS15260	COG3290	protein histidine kinase activity
CG479_RS15270	COG0584	glycerophosphoryl diester phosphodiesterase
CG479_RS15275	COG3093	addiction module antidote protein HigA
CG479_RS15280	COG0745	RESPONSE REGULATOR receiver
CG479_RS15290	COG0750	zinc metalloprotease
CG479_RS15295	COG0497	DNA recombination
CG479_RS15305	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG479_RS15310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG479_RS15320	COG1722	exodeoxyribonuclease VII activity
CG479_RS15325	COG1570	exodeoxyribonuclease VII activity
CG479_RS15330	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG479_RS15335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG479_RS15340	COG1302	Protein conserved in bacteria
CG479_RS15345	COG0439	Biotin carboxylase
CG479_RS15350	COG0511	ligase activity, forming carbon-carbon bonds
CG479_RS15395	COG3854	ATPases associated with a variety of cellular activities
CG479_RS15415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG479_RS15420	COG0006	proline dipeptidase activity
CG479_RS15425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG479_RS15435	COG3872	metal-dependent enzyme
CG479_RS15445	COG1321	iron dependent repressor
CG479_RS15460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG479_RS15470	COG1609	Transcriptional regulator
CG479_RS15480	COG2076	Multidrug Resistance protein
CG479_RS15485	COG2076	Multidrug Resistance protein
CG479_RS15505	COG1131	(ABC) transporter
CG479_RS15510	COG1725	Transcriptional regulator
CG479_RS15525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG479_RS15530	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG479_RS15535	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG479_RS15540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG479_RS15570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG479_RS15595	COG1459	type II secretion system
CG479_RS15620	COG4824	toxin secretion phage lysis holin
CG479_RS15705	COG3728	DNA packaging
CG479_RS15715	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG479_RS15780	COG1484	DNA-dependent DNA replication
CG479_RS15795	COG3723	Recombinational DNA repair protein, rece pathway
CG479_RS15800	COG5377	YqaJ viral recombinase family
CG479_RS15825	COG1396	sequence-specific DNA binding
CG479_RS15840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG479_RS15875	COG1078	dGTPase activity
CG479_RS15895	COG1410	methionine synthase
CG479_RS15895	COG0646	methionine synthase
CG479_RS15900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG479_RS15900	COG0646	methionine synthase
CG479_RS15905	COG0626	cystathionine gamma-synthase activity
CG479_RS15910	COG0626	cystathionine gamma-synthase activity
CG479_RS15930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG479_RS15940	COG1940	carbohydrate kinase activity
CG479_RS15945	COG4483	Protein conserved in bacteria
CG479_RS15950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG479_RS15955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG479_RS15960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG479_RS15965	COG0704	Plays a role in the regulation of phosphate uptake
CG479_RS15975	COG0581	inorganic phosphate transmembrane transporter activity
CG479_RS15980	COG0573	inorganic phosphate transmembrane transporter activity
CG479_RS15985	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG479_RS15990	COG0768	penicillin binding
CG479_RS15995	COG0477	Major facilitator Superfamily
CG479_RS16000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG479_RS16020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG479_RS16025	COG0735	belongs to the Fur family
CG479_RS16030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG479_RS16035	COG1121	(ABC) transporter
CG479_RS16040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS16050	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CG479_RS16065	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG479_RS16070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG479_RS16075	COG2384	SAM-dependent methyltransferase
CG479_RS16085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG479_RS16090	COG0358	DNA primase activity
CG479_RS16095	COG1671	Belongs to the UPF0178 family
CG479_RS16100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG479_RS16105	COG0517	IMP dehydrogenase activity
CG479_RS16110	COG1381	Involved in DNA repair and RecF pathway recombination
CG479_RS16120	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG479_RS16130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG479_RS16135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG479_RS16140	COG1480	7TM receptor with intracellular HD hydrolase
CG479_RS16145	COG1702	phosphate starvation-inducible protein PhoH
CG479_RS16160	COG1610	YqeY-like protein
CG479_RS16165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG479_RS16170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG479_RS16175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG479_RS16180	COG2264	protein methyltransferase activity
CG479_RS16185	COG0484	heat shock protein binding
CG479_RS16190	COG0443	Heat shock 70 kDa protein
CG479_RS16195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG479_RS16200	COG1420	regulation of RNA biosynthetic process
CG479_RS16205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG479_RS16210	COG1733	regulation of RNA biosynthetic process
CG479_RS16215	COG0693	protein deglycase activity
CG479_RS16220	COG0481	GTPase activity
CG479_RS16230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CG479_RS16235	COG0268	Binds directly to 16S ribosomal RNA
CG479_RS16240	COG1466	dna polymerase III delta subunit
CG479_RS16250	COG2333	competence protein COMEC
CG479_RS16250	COG0658	competence protein
CG479_RS16255	COG2131	deaminase
CG479_RS16260	COG1596	polysaccharide export
CG479_RS16260	COG1555	photosystem II stabilization
CG479_RS16265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG479_RS16270	COG2226	methyltransferase
CG479_RS16275	COG0799	negative regulation of ribosome biogenesis
CG479_RS16280	COG1713	HD superfamily hydrolase involved in NAD metabolism
CG479_RS16285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG479_RS16290	COG1534	Rna-binding protein
CG479_RS16295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG479_RS16300	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG479_RS16305	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CG479_RS16315	COG0688	phosphatidylethanolamine metabolic process
CG479_RS16330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG479_RS16335	COG2357	RelA SpoT domain protein
CG479_RS16340	COG1785	Belongs to the alkaline phosphatase family
CG479_RS16345	COG0456	acetyltransferase
CG479_RS16350	COG2267	carboxylic ester hydrolase activity
CG479_RS16375	COG3186	Phenylalanine-4-hydroxylase
CG479_RS16380	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG479_RS16385	COG2514	catechol 2,3-dioxygenase activity
CG479_RS16390	COG2259	Doxx family
CG479_RS16410	COG1609	Transcriptional regulator
CG479_RS16425	COG0626	cystathionine gamma-synthase activity
CG479_RS16430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG479_RS16435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG479_RS16440	COG2226	methyltransferase
CG479_RS16455	COG0768	penicillin binding
CG479_RS16465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG479_RS16470	COG0572	uridine kinase
CG479_RS16475	COG0826	peptidase U32
CG479_RS16480	COG0826	peptidase U32
CG479_RS16485	COG4122	O-methyltransferase activity
CG479_RS16490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG479_RS16500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG479_RS16505	COG4472	Bacterial protein of unknown function (DUF965)
CG479_RS16510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG479_RS16515	COG0628	permease
CG479_RS16535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG479_RS16545	COG0482	sulfurtransferase activity
CG479_RS16550	COG1104	cysteine desulfurase activity
CG479_RS16555	COG1959	2 iron, 2 sulfur cluster binding
CG479_RS16560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG479_RS16580	COG2207	Transcriptional regulator
CG479_RS16590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG479_RS16600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG479_RS16605	COG0124	histidyl-tRNA synthetase
CG479_RS16625	COG1490	D-aminoacyl-tRNA deacylase activity
CG479_RS16630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG479_RS16635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG479_RS16640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG479_RS16640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CG479_RS16645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG479_RS16650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG479_RS16650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG479_RS16660	COG2244	polysaccharide biosynthetic process
CG479_RS16685	COG1862	Preprotein translocase
CG479_RS16690	COG0343	queuine tRNA-ribosyltransferase activity
CG479_RS16695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG479_RS16705	COG2255	four-way junction helicase activity
CG479_RS16710	COG0632	four-way junction helicase activity
CG479_RS16715	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CG479_RS16735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CG479_RS16740	COG0157	Belongs to the NadC ModD family
CG479_RS16745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG479_RS16750	COG1104	cysteine desulfurase activity
CG479_RS16755	COG1827	regulation of RNA biosynthetic process
CG479_RS16760	COG2258	MOSC domain
CG479_RS16765	COG0077	Prephenate dehydratase
CG479_RS16770	COG0577	efflux transmembrane transporter activity
CG479_RS16775	COG0577	efflux transmembrane transporter activity
CG479_RS16780	COG1136	(ABC) transporter
CG479_RS16785	COG5002	protein histidine kinase activity
CG479_RS16790	COG0745	RESPONSE REGULATOR receiver
CG479_RS16800	COG3290	protein histidine kinase activity
CG479_RS16805	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG479_RS16810	COG2868	ribosomal protein
CG479_RS16815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CG479_RS16820	COG1530	ribonuclease E activity
CG479_RS16825	COG1994	Peptidase M50
CG479_RS16830	COG0739	heme binding
CG479_RS16835	COG2894	cell division
CG479_RS16840	COG0850	regulation of cytokinetic process
CG479_RS16850	COG1792	Involved in formation and maintenance of cell shape
CG479_RS16855	COG1077	Cell shape determining protein MreB Mrl
CG479_RS16875	COG0424	maF-like protein
CG479_RS16885	COG0285	dihydrofolate synthase activity
CG479_RS16910	COG1388	LysM domain
CG479_RS16910	COG1388	LysM domain
CG479_RS16915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG479_RS16920	COG0113	porphobilinogen synthase activity
CG479_RS16925	COG1587	Uroporphyrinogen-III synthase
CG479_RS16930	COG0181	hydroxymethylbilane synthase activity
CG479_RS16935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG479_RS16940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG479_RS16945	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG479_RS16955	COG1067	ATP-dependent peptidase activity
CG479_RS16955	COG0470	DNA polymerase III
CG479_RS16960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG479_RS16965	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG479_RS17005	COG1033	growth of symbiont in host cell
CG479_RS17005	COG2409	Drug exporters of the RND superfamily
CG479_RS17015	COG1309	transcriptional regulator
CG479_RS17035	COG0622	Phosphoesterase
CG479_RS17045	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG479_RS17050	COG5401	PFAM Sporulation and spore germination
CG479_RS17060	COG2197	response regulator
CG479_RS17070	COG1959	2 iron, 2 sulfur cluster binding
CG479_RS17075	COG1668	transmembrane transport
CG479_RS17080	COG4152	abc transporter atp-binding protein
CG479_RS17085	COG1360	Flagellar Motor Protein
CG479_RS17090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG479_RS17100	COG1876	peptidase activity
CG479_RS17110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG479_RS17115	COG1053	succinate dehydrogenase
CG479_RS17120	COG2009	succinate dehydrogenase
CG479_RS17125	COG1719	4-vinyl reductase, 4VR
CG479_RS17140	COG3118	belongs to the thioredoxin family
CG479_RS17145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CG479_RS17150	COG2086	electron transfer activity
CG479_RS17155	COG1024	Enoyl-CoA hydratase
CG479_RS17160	COG1309	transcriptional regulator
CG479_RS17165	COG0318	PFAM AMP-dependent synthetase and ligase
CG479_RS17175	COG2318	DinB family
CG479_RS17190	COG1131	(ABC) transporter
CG479_RS17195	COG2205	protein histidine kinase activity
CG479_RS17200	COG0745	RESPONSE REGULATOR receiver
CG479_RS17210	COG4895	conserved protein (DUF2196)
CG479_RS17215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG479_RS17220	COG1114	Component of the transport system for branched-chain amino acids
CG479_RS17225	COG1187	pseudouridine synthase activity
CG479_RS17235	COG1193	negative regulation of DNA recombination
CG479_RS17240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CG479_RS17240	COG1796	DNA polymerase
CG479_RS17245	COG1286	toxin biosynthetic process
CG479_RS17250	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CG479_RS17255	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG479_RS17275	COG0017	Asparaginyl-tRNA synthetase
CG479_RS17285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG479_RS17290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG479_RS17300	COG1418	mRNA catabolic process
CG479_RS17315	COG2814	Major facilitator Superfamily
CG479_RS17320	COG1566	PFAM secretion protein HlyD family protein
CG479_RS17325	COG1309	transcriptional regulator
CG479_RS17330	COG1363	Peptidase, m42
CG479_RS17340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG479_RS17345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG479_RS17355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG479_RS17365	COG1484	DNA-dependent DNA replication
CG479_RS17370	COG3611	Membrane attachment protein
CG479_RS17375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG479_RS17380	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CG479_RS17385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG479_RS17395	COG1971	Probably functions as a manganese efflux pump
CG479_RS17405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG479_RS17405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG479_RS17410	COG5002	protein histidine kinase activity
CG479_RS17415	COG0745	RESPONSE REGULATOR receiver
CG479_RS17425	COG0039	L-malate dehydrogenase activity
CG479_RS17430	COG0538	isocitrate dehydrogenase activity
CG479_RS17435	COG0372	Belongs to the citrate synthase family
CG479_RS17445	COG2707	UPF0756 membrane protein
CG479_RS17455	COG0628	permease
CG479_RS17460	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG479_RS17470	COG0205	6-phosphofructokinase activity
CG479_RS17475	COG0825	malonyl-CoA metabolic process
CG479_RS17480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG479_RS17485	COG1725	Transcriptional regulator
CG479_RS17490	COG0281	malic enzyme
CG479_RS17495	COG0587	DNA-directed DNA polymerase activity
CG479_RS17510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CG479_RS17525	COG4109	DRTGG domain
CG479_RS17530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG479_RS17535	COG0006	proline dipeptidase activity
CG479_RS17560	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS17565	COG0589	response to stress
CG479_RS17590	COG0165	Argininosuccinate lyase
CG479_RS17595	COG0137	argininosuccinate synthase activity
CG479_RS17605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS17615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG479_RS17620	COG0827	DNA restriction-modification system
CG479_RS17625	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CG479_RS17630	COG3874	Sporulation protein YtfJ
CG479_RS17645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CG479_RS17650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG479_RS17660	COG0301	tRNA thio-modification
CG479_RS17665	COG1104	cysteine desulfurase activity
CG479_RS17670	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CG479_RS17675	COG0583	DNA-binding transcription factor activity
CG479_RS17680	COG0697	spore germination
CG479_RS17685	COG1309	transcriptional regulator
CG479_RS17690	COG1956	GAF domain-containing protein
CG479_RS17695	COG0626	cystathionine gamma-synthase activity
CG479_RS17705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG479_RS17735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG479_RS17740	COG0454	-acetyltransferase
CG479_RS17745	COG0517	IMP dehydrogenase activity
CG479_RS17750	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG479_RS17755	COG1970	mechanosensitive ion channel activity
CG479_RS17765	COG1609	Transcriptional regulator
CG479_RS17775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG479_RS17775	COG1605	Chorismate mutase
CG479_RS17780	COG3118	belongs to the thioredoxin family
CG479_RS17790	COG2309	aminopeptidase activity
CG479_RS17805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG479_RS17815	COG1674	ftsk spoiiie
CG479_RS17825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG479_RS17830	COG4848	Belongs to the UPF0354 family
CG479_RS17835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG479_RS17840	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CG479_RS17850	COG0675	Transposase, IS605 OrfB family
CG479_RS17860	COG1363	Peptidase, m42
CG479_RS17870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG479_RS17875	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG479_RS17885	COG0510	thiamine kinase activity
CG479_RS17890	COG1523	belongs to the glycosyl hydrolase 13 family
CG479_RS17900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG479_RS17905	COG1349	DNA-binding transcription factor activity
CG479_RS17910	COG1187	pseudouridine synthase activity
CG479_RS17915	COG2244	polysaccharide biosynthetic process
CG479_RS17920	COG2081	HI0933 family
CG479_RS17935	COG3832	glyoxalase III activity
CG479_RS17955	COG0463	Glycosyl transferase, family 2
CG479_RS18005	COG1329	Transcriptional regulator
CG479_RS18015	COG2223	nitrite transmembrane transporter activity
CG479_RS18025	COG0314	molybdopterin synthase activity
CG479_RS18030	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG479_RS18035	COG0303	'Molybdopterin
CG479_RS18040	COG0315	cyclic pyranopterin monophosphate synthase activity
CG479_RS18045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG479_RS18050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG479_RS18055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG479_RS18060	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CG479_RS18065	COG1140	nitrate reductase beta subunit
CG479_RS18070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CG479_RS18075	COG2181	nitrate reductase activity
CG479_RS18090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG479_RS18100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG479_RS18140	COG0495	leucyl-tRNA aminoacylation
CG479_RS18145	COG2814	Major facilitator Superfamily
CG479_RS18155	COG1136	(ABC) transporter
CG479_RS18160	COG0346	lactoylglutathione lyase activity
CG479_RS18175	COG1242	4 iron, 4 sulfur cluster binding
CG479_RS18180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CG479_RS18185	COG1121	(ABC) transporter
CG479_RS18195	COG1794	racemase activity, acting on amino acids and derivatives
CG479_RS18205	COG2378	regulation of single-species biofilm formation
CG479_RS18215	COG2267	carboxylic ester hydrolase activity
CG479_RS18220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CG479_RS18230	COG0746	molybdenum cofactor guanylyltransferase activity
CG479_RS18255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG479_RS18265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG479_RS18310	COG3409	Peptidoglycan-binding domain 1 protein
CG479_RS18310	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG479_RS18320	COG1368	sulfuric ester hydrolase activity
CG479_RS18335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG479_RS18340	COG1116	anion transmembrane transporter activity
CG479_RS18345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG479_RS18360	COG0494	nUDIX hydrolase
CG479_RS18370	COG1854	S-ribosylhomocysteine lyase activity
CG479_RS18375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG479_RS18380	COG0288	reversible hydration of carbon dioxide
CG479_RS18385	COG1271	oxidase subunit
CG479_RS18390	COG1294	oxidase, subunit
CG479_RS18420	COG1842	Phage shock protein A
CG479_RS18460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CG479_RS18465	COG1597	lipid kinase activity
CG479_RS18470	COG1136	(ABC) transporter
CG479_RS18480	COG0745	RESPONSE REGULATOR receiver
CG479_RS18485	COG2205	protein histidine kinase activity
CG479_RS18490	COG0577	efflux transmembrane transporter activity
CG479_RS18495	COG1136	(ABC) transporter
CG479_RS18500	COG0577	efflux transmembrane transporter activity
CG479_RS18515	COG4948	Mandelate Racemase Muconate Lactonizing
CG479_RS18520	COG0318	PFAM AMP-dependent synthetase and ligase
CG479_RS18525	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG479_RS18530	COG0596	Alpha beta hydrolase
CG479_RS18535	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG479_RS18540	COG1169	isochorismate synthase
CG479_RS18545	COG1575	Belongs to the MenA family. Type 1 subfamily
CG479_RS18550	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG479_RS18570	COG0058	SHG alpha-glucan phosphorylase activity
CG479_RS18575	COG0297	glycogen (starch) synthase activity
CG479_RS18580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG479_RS18585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG479_RS18590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG479_RS18695	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG479_RS18730	COG1285	pathogenesis
CG479_RS18735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG479_RS18745	COG0166	Belongs to the GPI family
CG479_RS18755	COG2155	Conserved Protein
CG479_RS18760	COG1098	S1 RNA binding domain
CG479_RS18765	COG0436	Aminotransferase
CG479_RS18770	COG1522	sequence-specific DNA binding
CG479_RS18775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG479_RS18780	COG2267	carboxylic ester hydrolase activity
CG479_RS18790	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CG479_RS18795	COG2032	superoxide dismutase activity
CG479_RS18805	COG5018	Exonuclease
CG479_RS18810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG479_RS18830	COG2050	protein possibly involved in aromatic compounds catabolism
CG479_RS18840	COG1268	BioY protein
CG479_RS18845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG479_RS18850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG479_RS18860	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG479_RS18870	COG3584	3D domain protein
CG479_RS18890	COG1252	NADH dehydrogenase
CG479_RS18895	COG0492	ferredoxin-NADP+ reductase activity
CG479_RS18910	COG1683	Conserved Protein
CG479_RS18920	COG0316	Belongs to the HesB IscA family
CG479_RS18925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG479_RS18930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG479_RS18940	COG1252	NADH dehydrogenase
CG479_RS18945	COG2824	Alkylphosphonate utilization operon protein PhnA
CG479_RS18955	COG3655	Transcriptional regulator
CG479_RS18970	COG4837	Protein of unknown function (DUF1462)
CG479_RS18975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG479_RS18980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG479_RS18985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG479_RS18990	COG0647	UMP catabolic process
CG479_RS19000	COG2445	Protein of unknown function DUF86
CG479_RS19015	COG4470	Protein conserved in bacteria
CG479_RS19025	COG0789	Transcriptional regulator
CG479_RS19030	COG4377	Putative membrane peptidase family (DUF2324)
CG479_RS19045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG479_RS19050	COG0739	heme binding
CG479_RS19060	COG3377	Domain of unknown function (DUF1805)
CG479_RS19065	COG0737	Belongs to the 5'-nucleotidase family
CG479_RS19085	COG0719	Fe-S assembly protein
CG479_RS19090	COG0822	iron-sulfur transferase activity
CG479_RS19095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG479_RS19100	COG0719	Fe-S assembly protein
CG479_RS19105	COG0396	ATPase activity
CG479_RS19110	COG1464	Belongs to the NlpA lipoprotein family
CG479_RS19115	COG2011	ABC-type metal ion transport system permease component
CG479_RS19130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG479_RS19135	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CG479_RS19140	COG0509	glycine decarboxylation via glycine cleavage system
CG479_RS19145	COG1393	Belongs to the ArsC family
CG479_RS19185	COG1960	acyl-CoA dehydrogenase activity
CG479_RS19190	COG0183	Belongs to the thiolase family
CG479_RS19195	COG1024	Enoyl-CoA hydratase
CG479_RS19195	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG479_RS19205	COG1686	Belongs to the peptidase S11 family
CG479_RS19230	COG0011	TIGRFAM Protein of
CG479_RS19235	COG0840	transmembrane signaling receptor activity
CG479_RS19250	COG0531	amino acid
CG479_RS19255	COG0706	membrane insertase activity
CG479_RS19265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG479_RS19275	COG0586	Pfam SNARE associated Golgi protein
CG479_RS19285	COG1376	ErfK ybiS ycfS ynhG family protein
CG479_RS19290	COG0745	RESPONSE REGULATOR receiver
CG479_RS19295	COG5002	protein histidine kinase activity
CG479_RS19300	COG0840	transmembrane signaling receptor activity
CG479_RS19305	COG0840	transmembrane signaling receptor activity
CG479_RS19310	COG2151	metal-sulfur cluster biosynthetic enzyme
CG479_RS19315	COG3227	Zinc metalloprotease (Elastase)
CG479_RS19320	COG1741	Belongs to the pirin family
CG479_RS19335	COG0783	Belongs to the Dps family
CG479_RS19340	COG1611	Belongs to the LOG family
CG479_RS19375	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG479_RS19380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG479_RS19385	COG1121	(ABC) transporter
CG479_RS19410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG479_RS19415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG479_RS19420	COG1115	amino acid carrier protein
CG479_RS19425	COG2910	NAD(P)H-binding
CG479_RS19440	COG1252	NADH dehydrogenase
CG479_RS19455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG479_RS19470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG479_RS19475	COG1917	Cupin 2, conserved barrel domain protein
CG479_RS19475	COG4977	sequence-specific DNA binding
CG479_RS19485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CG479_RS19505	COG0697	spore germination
CG479_RS19515	COG1063	alcohol dehydrogenase
CG479_RS19525	COG2124	cytochrome p450
CG479_RS19530	COG0657	acetylesterase activity
CG479_RS19535	COG2124	cytochrome p450
CG479_RS19540	COG1309	transcriptional regulator
CG479_RS19545	COG0657	acetylesterase activity
CG479_RS19575	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG479_RS19580	COG0557	exoribonuclease II activity
CG479_RS19585	COG1647	Serine aminopeptidase, S33
CG479_RS19590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG479_RS19595	COG1346	cytolysis
CG479_RS19605	COG0148	phosphopyruvate hydratase activity
CG479_RS19610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG479_RS19615	COG0149	triose-phosphate isomerase activity
CG479_RS19620	COG0126	phosphoglycerate kinase activity
CG479_RS19625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG479_RS19640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG479_RS19665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG479_RS19680	COG2323	membrane
CG479_RS19695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG479_RS19700	COG1481	regulation of sporulation
CG479_RS19705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CG479_RS19710	COG1660	Displays ATPase and GTPase activities
CG479_RS19715	COG1051	belongs to the nudix hydrolase family
CG479_RS19725	COG0492	ferredoxin-NADP+ reductase activity
CG479_RS19730	COG0457	Tetratricopeptide repeat
CG479_RS19735	COG0110	maltose O-acetyltransferase activity
CG479_RS19745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG479_RS19750	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG479_RS19755	COG1950	PFAM Membrane protein of
CG479_RS19765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG479_RS19780	COG0789	Transcriptional regulator
CG479_RS19800	COG0583	DNA-binding transcription factor activity
CG479_RS19815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG479_RS19820	COG0793	Belongs to the peptidase S41A family
CG479_RS19820	COG3409	Peptidoglycan-binding domain 1 protein
CG479_RS19825	COG2177	Part of the ABC transporter FtsEX involved in
CG479_RS19830	COG2884	Cell division ATP-binding protein ftsE
CG479_RS19855	COG1278	Cold shock
CG479_RS19860	COG1040	competence protein
CG479_RS19865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CG479_RS19870	COG0791	NLP P60 protein
CG479_RS19870	COG1388	LysM domain
CG479_RS19875	COG1733	regulation of RNA biosynthetic process
CG479_RS19880	COG1307	EDD domain protein, DegV family
CG479_RS19885	COG1739	Uncharacterized protein family UPF0029
CG479_RS19890	COG1316	TRANSCRIPTIONal
CG479_RS19910	COG0457	Tetratricopeptide repeat
CG479_RS19940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CG479_RS19950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG479_RS19960	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CG479_RS19960	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CG479_RS19975	COG1486	melibiose metabolic process
CG479_RS19980	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG479_RS19995	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG479_RS20000	COG1301	dicarboxylic acid transport
CG479_RS20005	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CG479_RS20010	COG1271	oxidase subunit
CG479_RS20015	COG1294	oxidase, subunit
CG479_RS20020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG479_RS20025	COG1620	l-lactate permease
CG479_RS20030	COG2389	metal-binding protein
CG479_RS20040	COG1368	sulfuric ester hydrolase activity
CG479_RS20050	COG1388	LysM domain
CG479_RS20050	COG0791	NLP P60 protein
CG479_RS20055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG479_RS20065	COG1215	transferase activity, transferring glycosyl groups
CG479_RS20075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG479_RS20080	COG1388	LysM domain
CG479_RS20080	COG3584	3D domain protein
CG479_RS20095	COG4715	Zinc finger, swim domain protein
CG479_RS20100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG479_RS20140	COG0577	efflux transmembrane transporter activity
CG479_RS20145	COG1136	(ABC) transporter
CG479_RS20180	COG3850	Histidine kinase
CG479_RS20180	COG5002	protein histidine kinase activity
CG479_RS20185	COG0745	RESPONSE REGULATOR receiver
CG479_RS20195	COG1316	TRANSCRIPTIONal
CG479_RS20200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG479_RS20210	COG1609	Transcriptional regulator
CG479_RS20220	COG0739	heme binding
CG479_RS20235	COG3279	Response regulator of the LytR AlgR family
CG479_RS20240	COG2385	sporulation resulting in formation of a cellular spore
CG479_RS20255	COG4836	Membrane
CG479_RS20260	COG1007	ATP synthesis coupled electron transport
CG479_RS20265	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG479_RS20270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG479_RS20275	COG0713	ATP synthesis coupled electron transport
CG479_RS20280	COG0839	Belongs to the complex I subunit 6 family
CG479_RS20290	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CG479_RS20295	COG0649	NAD binding
CG479_RS20300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG479_RS20305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG479_RS20310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG479_RS20315	COG5001	Diguanylate cyclase
CG479_RS20315	COG3300	MHYT domain
CG479_RS20320	COG5001	Diguanylate cyclase
CG479_RS20320	COG3300	MHYT domain
CG479_RS20335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG479_RS20340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG479_RS20345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG479_RS20350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG479_RS20355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG479_RS20360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG479_RS20365	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG479_RS20390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG479_RS20395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG479_RS20405	COG0698	ribose 5-phosphate isomerase
CG479_RS20430	COG2259	Doxx family
CG479_RS20435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG479_RS20450	COG0009	L-threonylcarbamoyladenylate synthase
CG479_RS20465	COG2890	protein-(glutamine-N5) methyltransferase activity
CG479_RS20470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG479_RS20475	COG1435	thymidine kinase activity
CG479_RS20485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG479_RS20490	COG1494	fructose-1,6-bisphosphatase
CG479_RS20510	COG4821	SIS domain
CG479_RS20515	COG0504	CTP synthase activity
CG479_RS20530	COG1960	acyl-CoA dehydrogenase activity
CG479_RS20535	COG1960	acyl-CoA dehydrogenase activity
CG479_RS20540	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG479_RS20545	COG0183	Belongs to the thiolase family
CG479_RS20550	COG2181	nitrate reductase activity
CG479_RS20550	COG0247	lactate metabolic process
CG479_RS20555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG479_RS20575	COG2197	response regulator
CG479_RS20580	COG4585	Histidine kinase
CG479_RS20585	COG0842	Transport permease protein
CG479_RS20590	COG1131	(ABC) transporter
CG479_RS20600	COG2234	aminopeptidase activity
CG479_RS20615	COG4506	Protein conserved in bacteria
CG479_RS20620	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG479_RS20640	COG0010	Belongs to the arginase family
CG479_RS20645	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CG479_RS20650	COG2814	Major facilitator Superfamily
CG479_RS20655	COG0789	Transcriptional regulator
CG479_RS20660	COG0584	glycerophosphoryl diester phosphodiesterase
CG479_RS20665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG479_RS20670	COG2801	Transposase and inactivated derivatives
CG479_RS20675	COG1404	Belongs to the peptidase S8 family
CG479_RS20695	COG1994	Peptidase M50
CG479_RS20705	COG1078	dGTPase activity
CG479_RS20710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG479_RS20715	COG1120	ATPase activity
CG479_RS20720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS20725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG479_RS20730	COG4844	belongs to the
CG479_RS20745	COG0280	phosphate acetyltransferase
CG479_RS20750	COG3253	May function as heme-dependent peroxidase
CG479_RS20760	COG3773	Cell wall hydrolase
CG479_RS20770	COG2363	Small membrane protein
CG479_RS20780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG479_RS20785	COG2233	PERMEase
CG479_RS20790	COG0561	phosphatase activity
CG479_RS20795	COG2814	Major facilitator Superfamily
CG479_RS20800	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG479_RS20805	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG479_RS20810	COG1131	(ABC) transporter
CG479_RS20815	COG2755	lipolytic protein G-D-S-L family
CG479_RS20820	COG0460	homoserine dehydrogenase
CG479_RS20825	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CG479_RS20830	COG2873	o-acetylhomoserine
CG479_RS20840	COG0351	phosphomethylpyrimidine kinase
CG479_RS20850	COG1966	Carbon starvation protein
CG479_RS20855	COG3279	Response regulator of the LytR AlgR family
CG479_RS20865	COG0477	Major facilitator Superfamily
CG479_RS20875	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CG479_RS20880	COG0438	transferase activity, transferring glycosyl groups
CG479_RS20895	COG0840	transmembrane signaling receptor activity
CG479_RS20920	COG1607	acyl-coa hydrolase
CG479_RS20925	COG1216	Glycosyl transferase, family 2
CG479_RS20940	COG0463	Glycosyl transferase, family 2
CG479_RS20955	COG0463	Glycosyl transferase, family 2
CG479_RS20960	COG0488	(ABC) transporter
CG479_RS20965	COG1309	transcriptional regulator
CG479_RS20970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG479_RS20975	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG479_RS20975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG479_RS20980	COG0628	permease
CG479_RS20985	COG1346	cytolysis
CG479_RS20995	COG3279	Response regulator of the LytR AlgR family
CG479_RS21000	COG3275	phosphorelay sensor kinase activity
CG479_RS21005	COG2814	Major facilitator Superfamily
CG479_RS21010	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CG479_RS21015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG479_RS21030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG479_RS21035	COG3711	transcriptional antiterminator
CG479_RS21035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG479_RS21135	COG0457	Tetratricopeptide repeat
CG479_RS21185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG479_RS21190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG479_RS21200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG479_RS21205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG479_RS21210	COG4853	Protein conserved in bacteria
CG479_RS21220	COG5002	protein histidine kinase activity
CG479_RS21225	COG0745	RESPONSE REGULATOR receiver
CG479_RS21250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG479_RS21255	COG0305	Participates in initiation and elongation during chromosome replication
CG479_RS21260	COG0359	binds to the 23S rRNA
CG479_RS21265	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CG479_RS21270	COG4241	membrane
CG479_RS21275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG479_RS21285	COG0360	Binds together with S18 to 16S ribosomal RNA
CG479_RS21290	COG0012	GTP binding
CG479_RS21295	COG4481	Protein conserved in bacteria
CG479_RS21300	COG0668	transmembrane transport
CG479_RS21310	COG1475	DNA binding
CG479_RS21315	COG1192	Involved in chromosome partitioning
CG479_RS21320	COG1475	DNA binding
CG479_RS21325	COG0357	Ribosomal RNA small subunit methyltransferase G
CG479_RS21330	COG0445	tRNA wobble uridine modification
CG479_RS21335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG479_RS21340	COG1847	R3H domain protein
CG479_RS21345	COG0706	membrane insertase activity
CG479_RS21350	COG0594	ribonuclease P activity
CG479_RS21355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CG479_RS21395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG479_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
CG479_RS21470	COG0583	DNA-binding transcription factor activity
CG479_RS21495	COG4974	Belongs to the 'phage' integrase family
CG479_RS21530	COG4166	transmembrane transport
CG479_RS21540	COG0457	Tetratricopeptide repeat
CG479_RS21580	COG1192	Involved in chromosome partitioning
CG479_RS21730	COG0741	lytic transglycosylase activity
CG479_RS21730	COG0791	NLP P60 protein