locus-tag	class	description
CG482_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG482_RS00010	COG0592	DNA-directed DNA polymerase activity
CG482_RS00015	COG2501	S4 domain
CG482_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG482_RS00025	COG0187	DNA topoisomerase II activity
CG482_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG482_RS00065	COG0517	IMP dehydrogenase activity
CG482_RS00065	COG0516	GMP reductase activity
CG482_RS00070	COG1686	Belongs to the peptidase S11 family
CG482_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CG482_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CG482_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG482_RS00100	COG1428	Deoxynucleoside kinase
CG482_RS00105	COG1428	Deoxynucleoside kinase
CG482_RS00110	COG1335	isochorismatase
CG482_RS00115	COG0590	tRNA wobble adenosine to inosine editing
CG482_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG482_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG482_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG482_RS00180	COG1982	Orn Lys Arg decarboxylase major
CG482_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG482_RS00190	COG0470	DNA polymerase III
CG482_RS00195	COG1774	PSP1 C-terminal conserved region
CG482_RS00200	COG4467	Involved in initiation control of chromosome replication
CG482_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CG482_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG482_RS00220	COG2002	toxin-antitoxin pair type II binding
CG482_RS00230	COG0084	hydrolase, TatD family'
CG482_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG482_RS00250	COG4466	Protein conserved in bacteria
CG482_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG482_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG482_RS00270	COG0251	oxidation-reduction process
CG482_RS00275	COG2088	sporulation resulting in formation of a cellular spore
CG482_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG482_RS00290	COG0193	aminoacyl-tRNA hydrolase activity
CG482_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG482_RS00305	COG2002	toxin-antitoxin pair type II binding
CG482_RS00310	COG2244	polysaccharide biosynthetic process
CG482_RS00315	COG3956	TIGRFAM MazG family protein
CG482_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CG482_RS00340	COG1098	S1 RNA binding domain
CG482_RS00355	COG2208	phosphoserine phosphatase activity
CG482_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CG482_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG482_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CG482_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG482_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG482_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
CG482_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG482_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG482_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG482_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG482_RS00420	COG1396	sequence-specific DNA binding
CG482_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG482_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG482_RS00465	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_RS00515	COG3880	PFAM UvrB UvrC protein
CG482_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CG482_RS00525	COG0542	response to heat
CG482_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CG482_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
CG482_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG482_RS00550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG482_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG482_RS00560	COG1045	serine acetyltransferase
CG482_RS00565	COG0215	cysteine-tRNA ligase activity
CG482_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG482_RS00580	COG3688	RNA-binding protein containing a PIN domain
CG482_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG482_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
CG482_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CG482_RS00610	COG0081	regulation of translation
CG482_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG482_RS00620	COG0222	ribosome binding
CG482_RS00625	COG2813	Specifically methylates the guanine in position
CG482_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG482_RS00640	COG1358	cellular component organization or biogenesis
CG482_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG482_RS00650	COG0049	tRNA binding
CG482_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG482_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG482_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG482_RS00675	COG0088	Forms part of the polypeptide exit tunnel
CG482_RS00680	COG0089	rRNA binding
CG482_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG482_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG482_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG482_RS00700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG482_RS00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG482_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
CG482_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG482_RS00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG482_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG482_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG482_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG482_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG482_RS00755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG482_RS00760	COG1841	ribosomal large subunit assembly
CG482_RS00765	COG0200	Binds to the 23S rRNA
CG482_RS00770	COG0201	protein transport
CG482_RS00775	COG0563	adenylate kinase activity
CG482_RS00780	COG0024	Methionine aminopeptidase
CG482_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG482_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CG482_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG482_RS00805	COG0202	RNA polymerase activity
CG482_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG482_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG482_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG482_RS00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG482_RS00860	COG0489	protein tyrosine kinase activity
CG482_RS00870	COG2194	sulfuric ester hydrolase activity
CG482_RS00875	COG0726	polysaccharide deacetylase
CG482_RS00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CG482_RS00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG482_RS01030	COG0457	Tetratricopeptide repeat
CG482_RS01055	COG1266	CAAX protease self-immunity
CG482_RS01130	COG3681	Belongs to the UPF0597 family
CG482_RS01135	COG3681	Belongs to the UPF0597 family
CG482_RS01165	COG2814	Major facilitator Superfamily
CG482_RS01175	COG0601	transmembrane transport
CG482_RS01180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG482_RS01185	COG0444	Belongs to the ABC transporter superfamily
CG482_RS01190	COG4608	Belongs to the ABC transporter superfamily
CG482_RS01195	COG4166	transmembrane transport
CG482_RS01215	COG1309	transcriptional regulator
CG482_RS01225	COG0656	L-ascorbic acid biosynthetic process
CG482_RS01230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG482_RS01240	COG4149	molybdate abc transporter
CG482_RS01245	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG482_RS01250	COG1910	domain protein
CG482_RS01255	COG0204	Acyl-transferase
CG482_RS01260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS01265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG482_RS01265	COG1648	precorrin-2 dehydrogenase activity
CG482_RS01275	COG1587	Uroporphyrinogen-III synthase
CG482_RS01275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG482_RS01280	COG2146	nitrite reductase [NAD(P)H] activity
CG482_RS01285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG482_RS01315	COG4585	Histidine kinase
CG482_RS01320	COG2197	response regulator
CG482_RS01325	COG1131	(ABC) transporter
CG482_RS01330	COG1511	domain protein
CG482_RS01330	COG0842	Transport permease protein
CG482_RS01335	COG0842	Transport permease protein
CG482_RS01345	COG0747	negative chemotaxis
CG482_RS01350	COG0601	transmembrane transport
CG482_RS01360	COG0444	Belongs to the ABC transporter superfamily
CG482_RS01365	COG4608	Belongs to the ABC transporter superfamily
CG482_RS01370	COG0561	phosphatase activity
CG482_RS01390	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CG482_RS01395	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG482_RS01405	COG2814	Major facilitator Superfamily
CG482_RS01410	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG482_RS01415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CG482_RS01425	COG0705	Rhomboid family
CG482_RS01425	COG0457	Tetratricopeptide repeat
CG482_RS01430	COG0736	holo-[acyl-carrier-protein] synthase activity
CG482_RS01435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG482_RS01445	COG0864	Transcriptional regulator
CG482_RS01450	COG2337	Toxic component of a toxin-antitoxin (TA) module
CG482_RS01455	COG2183	response to ionizing radiation
CG482_RS01465	COG3091	SprT-like family
CG482_RS01505	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_RS01555	COG0802	atpase or kinase
CG482_RS01560	COG1214	PFAM Peptidase M22, glycoprotease
CG482_RS01565	COG0456	acetyltransferase
CG482_RS01575	COG0488	(ABC) transporter
CG482_RS01580	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CG482_RS01590	COG1266	CAAX protease self-immunity
CG482_RS01595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG482_RS01600	COG0459	protein refolding
CG482_RS01605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG482_RS01605	COG0519	Catalyzes the synthesis of GMP from XMP
CG482_RS01610	COG2252	PERMEase
CG482_RS01620	COG5002	protein histidine kinase activity
CG482_RS01690	COG2205	protein histidine kinase activity
CG482_RS01695	COG0745	RESPONSE REGULATOR receiver
CG482_RS01715	COG0697	spore germination
CG482_RS01740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG482_RS01745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG482_RS01750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG482_RS01755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG482_RS01760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG482_RS01765	COG0047	phosphoribosylformylglycinamidine synthase activity
CG482_RS01770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG482_RS01775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG482_RS01780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG482_RS01785	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG482_RS01790	COG0138	bifunctional purine biosynthesis protein purh
CG482_RS01795	COG0151	Belongs to the GarS family
CG482_RS01805	COG0583	DNA-binding transcription factor activity
CG482_RS01825	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CG482_RS01830	COG0210	DNA helicase
CG482_RS01835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG482_RS01840	COG4851	CamS sex pheromone cAM373 precursor
CG482_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS01855	COG1335	isochorismatase
CG482_RS01865	COG2011	ABC-type metal ion transport system permease component
CG482_RS01885	COG4682	membrane
CG482_RS01890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG482_RS01895	COG0154	amidase activity
CG482_RS01900	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG482_RS01905	COG1597	lipid kinase activity
CG482_RS01910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG482_RS01915	COG0546	phosphoglycolate phosphatase activity
CG482_RS01920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG482_RS01930	COG0531	amino acid
CG482_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS01940	COG2076	Multidrug Resistance protein
CG482_RS01945	COG2309	aminopeptidase activity
CG482_RS01955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_RS01960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG482_RS01965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG482_RS01980	COG0450	alkyl hydroperoxide reductase
CG482_RS02005	COG0714	Associated with various cellular activities
CG482_RS02040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS02045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS02050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG482_RS02055	COG0492	ferredoxin-NADP+ reductase activity
CG482_RS02065	COG0166	Belongs to the GPI family
CG482_RS02070	COG5002	protein histidine kinase activity
CG482_RS02100	COG2814	Major facilitator Superfamily
CG482_RS02105	COG0723	plastoquinol--plastocyanin reductase activity
CG482_RS02105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG482_RS02115	COG0765	amino acid transport
CG482_RS02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_RS02130	COG0840	transmembrane signaling receptor activity
CG482_RS02140	COG2235	arginine
CG482_RS02155	COG0549	Belongs to the carbamate kinase family
CG482_RS02160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG482_RS02170	COG0366	Alpha amylase catalytic
CG482_RS02175	COG2190	(PTS) system
CG482_RS02175	COG1263	PTS System
CG482_RS02175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_RS02195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS02200	COG4605	iron ion homeostasis
CG482_RS02205	COG4604	ABC transporter, ATP-binding protein
CG482_RS02210	COG4607	ABC-type enterochelin transport system periplasmic component
CG482_RS02215	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CG482_RS02220	COG0352	thiamine-phosphate diphosphorylase activity
CG482_RS02225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CG482_RS02245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_RS02255	COG1116	anion transmembrane transporter activity
CG482_RS02295	COG2270	Major facilitator Superfamily
CG482_RS02320	COG2310	stress, protein
CG482_RS02325	COG2310	stress, protein
CG482_RS02330	COG2310	stress, protein
CG482_RS02335	COG0861	Integral membrane protein TerC family
CG482_RS02345	COG3853	Toxic anion resistance protein (TelA)
CG482_RS02355	COG4840	Belongs to the UPF0435 family
CG482_RS02360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG482_RS02370	COG1295	ribonuclease BN
CG482_RS02375	COG2217	Heavy metal translocating P-type atpase
CG482_RS02380	COG0697	spore germination
CG482_RS02390	COG0681	Belongs to the peptidase S26 family
CG482_RS02400	COG0586	Pfam SNARE associated Golgi protein
CG482_RS02425	COG0535	radical SAM domain protein
CG482_RS02445	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CG482_RS02480	COG2066	Belongs to the glutaminase family
CG482_RS02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_RS02485	COG1263	PTS System
CG482_RS02500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG482_RS02500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG482_RS02510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CG482_RS02515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG482_RS02530	COG0402	S-adenosylhomocysteine deaminase activity
CG482_RS02535	COG2137	regulation of response to DNA damage stimulus
CG482_RS02560	COG1988	membrane-bound metal-dependent
CG482_RS02565	COG1194	a g-specific adenine glycosylase
CG482_RS02590	COG3557	Belongs to the UPF0374 family
CG482_RS02595	COG1132	(ABC) transporter
CG482_RS02600	COG4129	membrane
CG482_RS02605	COG0067	glutamate synthase
CG482_RS02605	COG0069	glutamate synthase activity
CG482_RS02605	COG0070	glutamate synthase
CG482_RS02610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG482_RS02615	COG4555	ABC transporter
CG482_RS02635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG482_RS02640	COG0735	belongs to the Fur family
CG482_RS02760	COG0457	Tetratricopeptide repeat
CG482_RS02765	COG0217	transcriptional regulatory protein
CG482_RS02770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG482_RS02775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG482_RS02795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG482_RS02805	COG2766	serine protein kinase
CG482_RS02815	COG2718	Belongs to the UPF0229 family
CG482_RS02830	COG1280	lysine exporter protein (LysE YggA)
CG482_RS02870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG482_RS02880	COG1585	Membrane protein implicated in regulation of membrane protease activity
CG482_RS02885	COG2268	Band 7 protein
CG482_RS02920	COG3290	protein histidine kinase activity
CG482_RS02925	COG4565	transcriptional regulatory protein
CG482_RS02930	COG3493	citrate carrier protein
CG482_RS02935	COG0281	malic enzyme
CG482_RS02950	COG5002	protein histidine kinase activity
CG482_RS02955	COG0745	RESPONSE REGULATOR receiver
CG482_RS02965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG482_RS02970	COG3383	formate dehydrogenase (NAD+) activity
CG482_RS02975	COG2427	Protein of unknown function (DUF1641)
CG482_RS02985	COG0840	transmembrane signaling receptor activity
CG482_RS02995	COG0531	amino acid
CG482_RS03015	COG0640	Transcriptional regulator
CG482_RS03025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG482_RS03035	COG3227	Zinc metalloprotease (Elastase)
CG482_RS03050	COG2217	Heavy metal translocating P-type atpase
CG482_RS03070	COG2720	vancomycin resistance protein
CG482_RS03075	COG1316	TRANSCRIPTIONal
CG482_RS03085	COG1253	flavin adenine dinucleotide binding
CG482_RS03090	COG1027	Aspartate ammonia-lyase
CG482_RS03095	COG1620	l-lactate permease
CG482_RS03115	COG3104	oligopeptide transport
CG482_RS03120	COG0156	8-amino-7-oxononanoate synthase activity
CG482_RS03125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG482_RS03130	COG4548	von Willebrand factor, type A
CG482_RS03135	COG0714	Associated with various cellular activities
CG482_RS03140	COG0531	amino acid
CG482_RS03145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_RS03160	COG1126	abc transporter atp-binding protein
CG482_RS03165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_RS03170	COG0765	amino acid transport
CG482_RS03175	COG0765	amino acid transport
CG482_RS03180	COG0833	amino acid
CG482_RS03190	COG5002	protein histidine kinase activity
CG482_RS03205	COG0659	secondary active sulfate transmembrane transporter activity
CG482_RS03210	COG0589	response to stress
CG482_RS03220	COG0747	negative chemotaxis
CG482_RS03230	COG0601	transmembrane transport
CG482_RS03235	COG4608	Belongs to the ABC transporter superfamily
CG482_RS03245	COG2271	Major facilitator Superfamily
CG482_RS03250	COG1846	Transcriptional regulator
CG482_RS03255	COG0477	Major facilitator Superfamily
CG482_RS03260	COG1609	Transcriptional regulator
CG482_RS03265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG482_RS03270	COG1869	D-ribose catabolic process
CG482_RS03280	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG482_RS03285	COG1879	ABC-type sugar transport system periplasmic component
CG482_RS03290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG482_RS03305	COG3568	Endonuclease Exonuclease Phosphatase
CG482_RS03330	COG0840	transmembrane signaling receptor activity
CG482_RS03335	COG3584	3D domain protein
CG482_RS03335	COG1388	LysM domain
CG482_RS03340	COG1476	TRANSCRIPTIONal
CG482_RS03375	COG1114	Component of the transport system for branched-chain amino acids
CG482_RS03385	COG1113	amino acid transport
CG482_RS03390	COG2153	protein acetylation
CG482_RS03400	COG0475	glutathione-regulated potassium exporter activity
CG482_RS03400	COG0569	domain protein
CG482_RS03415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG482_RS03420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG482_RS03425	COG0833	amino acid
CG482_RS03430	COG4990	cell redox homeostasis
CG482_RS03445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS03450	COG0697	spore germination
CG482_RS03455	COG0531	amino acid
CG482_RS03465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG482_RS03470	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG482_RS03475	COG1918	ferrous iron import across plasma membrane
CG482_RS03475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CG482_RS03480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG482_RS03485	COG0573	inorganic phosphate transmembrane transporter activity
CG482_RS03490	COG0581	inorganic phosphate transmembrane transporter activity
CG482_RS03495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG482_RS03535	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_RS03610	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CG482_RS03635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG482_RS03640	COG1116	anion transmembrane transporter activity
CG482_RS03645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_RS03650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG482_RS03655	COG0352	thiamine-phosphate diphosphorylase activity
CG482_RS03660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG482_RS03665	COG2104	thiamine diphosphate biosynthetic process
CG482_RS03670	COG2022	thiamine diphosphate biosynthetic process
CG482_RS03675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_RS03680	COG0351	phosphomethylpyrimidine kinase
CG482_RS03710	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG482_RS03715	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG482_RS03720	COG2205	protein histidine kinase activity
CG482_RS03725	COG2814	Major facilitator Superfamily
CG482_RS03730	COG1846	Transcriptional regulator
CG482_RS03740	COG2252	PERMEase
CG482_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS03750	COG1376	ErfK ybiS ycfS ynhG family protein
CG482_RS03805	COG0778	Nitroreductase
CG482_RS03815	COG2719	SpoVR family
CG482_RS03825	COG1316	TRANSCRIPTIONal
CG482_RS03830	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG482_RS03845	COG0577	efflux transmembrane transporter activity
CG482_RS03850	COG1136	(ABC) transporter
CG482_RS03860	COG1114	Component of the transport system for branched-chain amino acids
CG482_RS03865	COG3546	catalase activity
CG482_RS03920	COG0475	glutathione-regulated potassium exporter activity
CG482_RS03925	COG1737	Transcriptional regulator
CG482_RS03935	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CG482_RS03940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_RS03940	COG1263	PTS System
CG482_RS03955	COG1522	sequence-specific DNA binding
CG482_RS03970	COG0531	amino acid
CG482_RS03980	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS03990	COG1132	(ABC) transporter
CG482_RS03995	COG1132	(ABC) transporter
CG482_RS04005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_RS04010	COG0765	amino acid transport
CG482_RS04015	COG1126	abc transporter atp-binding protein
CG482_RS04030	COG0189	ligase activity
CG482_RS04035	COG4399	Belongs to the UPF0754 family
CG482_RS04040	COG3679	Belongs to the UPF0342 family
CG482_RS04045	COG4585	Histidine kinase
CG482_RS04050	COG2197	response regulator
CG482_RS04100	COG2094	Belongs to the DNA glycosylase MPG family
CG482_RS04105	COG0561	phosphatase activity
CG482_RS04115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG482_RS04145	COG2244	polysaccharide biosynthetic process
CG482_RS04155	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG482_RS04175	COG1696	Membrane protein involved in D-alanine export
CG482_RS04190	COG1024	Enoyl-CoA hydratase
CG482_RS04200	COG1363	Peptidase, m42
CG482_RS04215	COG2239	Acts as a magnesium transporter
CG482_RS04225	COG1115	amino acid carrier protein
CG482_RS04295	COG1476	TRANSCRIPTIONal
CG482_RS04425	COG3290	protein histidine kinase activity
CG482_RS04425	COG3829	transcription factor binding
CG482_RS04450	COG1061	Type III restriction enzyme res subunit
CG482_RS04485	COG1472	Belongs to the glycosyl hydrolase 3 family
CG482_RS04490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CG482_RS04495	COG3829	transcription factor binding
CG482_RS04500	COG4638	Rieske (2fe-2S)
CG482_RS04505	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS04510	COG0473	3-isopropylmalate dehydrogenase activity
CG482_RS04520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS04530	COG1064	alcohol dehydrogenase
CG482_RS04545	COG3246	L-lysine catabolic process to acetate
CG482_RS04590	COG4641	Protein conserved in bacteria
CG482_RS04605	COG3711	transcriptional antiterminator
CG482_RS04610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_RS04610	COG2190	(PTS) system
CG482_RS04610	COG1263	PTS System
CG482_RS04615	COG2723	6-phospho-beta-galactosidase activity
CG482_RS04625	COG2376	Dihydroxyacetone kinase
CG482_RS04660	COG0420	3'-5' exonuclease activity
CG482_RS04665	COG4717	serine-type aminopeptidase activity
CG482_RS04670	COG3481	metal-dependent phosphohydrolase, HD sub domain
CG482_RS04685	COG1136	(ABC) transporter
CG482_RS04695	COG5002	protein histidine kinase activity
CG482_RS04700	COG0745	RESPONSE REGULATOR receiver
CG482_RS04710	COG1316	TRANSCRIPTIONal
CG482_RS04725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CG482_RS04730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG482_RS04735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG482_RS04740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG482_RS04765	COG1846	Transcriptional regulator
CG482_RS04770	COG4980	gas vesicle protein
CG482_RS04780	COG0537	adenosine 5'-monophosphoramidase activity
CG482_RS04790	COG1131	(ABC) transporter
CG482_RS04795	COG4473	ABC transporter
CG482_RS04815	COG3402	PFAM membrane-flanked domain
CG482_RS04825	COG2329	Antibiotic biosynthesis monooxygenase
CG482_RS04830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_RS04835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG482_RS04840	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CG482_RS04845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CG482_RS04875	COG1309	transcriptional regulator
CG482_RS04885	COG0438	transferase activity, transferring glycosyl groups
CG482_RS04885	COG1216	Glycosyl transferase, family 2
CG482_RS04900	COG1609	Transcriptional regulator
CG482_RS04910	COG1234	tRNA 3'-trailer cleavage
CG482_RS04915	COG0095	Lipoate-protein ligase
CG482_RS04925	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_RS04940	COG2205	protein histidine kinase activity
CG482_RS04945	COG0745	RESPONSE REGULATOR receiver
CG482_RS04965	COG0501	Belongs to the peptidase M48B family
CG482_RS04970	COG0840	transmembrane signaling receptor activity
CG482_RS04975	COG0697	spore germination
CG482_RS04995	COG2224	Isocitrate lyase
CG482_RS05000	COG1278	Cold shock
CG482_RS05010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG482_RS05020	COG1396	sequence-specific DNA binding
CG482_RS05110	COG1598	PFAM Uncharacterised protein family UPF0150
CG482_RS05230	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG482_RS05245	COG2207	Transcriptional regulator
CG482_RS05245	COG3708	Transcriptional regulator
CG482_RS05280	COG0398	Pfam SNARE associated Golgi protein
CG482_RS05290	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CG482_RS05295	COG1074	ATP-dependent DNA helicase activity
CG482_RS05335	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG482_RS05355	COG0367	asparagine synthase
CG482_RS05365	COG0753	catalase activity
CG482_RS05375	COG1874	Beta-galactosidase
CG482_RS05375	COG0366	Alpha amylase catalytic
CG482_RS05380	COG1666	GTP binding
CG482_RS05385	COG2996	Protein conserved in bacteria
CG482_RS05400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS05415	COG0561	phosphatase activity
CG482_RS05435	COG2267	carboxylic ester hydrolase activity
CG482_RS05450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG482_RS05455	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG482_RS05460	COG5504	Zn-dependent protease
CG482_RS05475	COG0180	Tryptophanyl-tRNA synthetase
CG482_RS05495	COG4166	transmembrane transport
CG482_RS05500	COG0601	transmembrane transport
CG482_RS05505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG482_RS05510	COG0444	Belongs to the ABC transporter superfamily
CG482_RS05515	COG4608	Belongs to the ABC transporter superfamily
CG482_RS05520	COG0534	Mate efflux family protein
CG482_RS05525	COG4166	transmembrane transport
CG482_RS05545	COG0861	Integral membrane protein TerC family
CG482_RS05565	COG1164	Oligoendopeptidase f
CG482_RS05575	COG2346	COG2346, Truncated hemoglobins
CG482_RS05580	COG4116	CYTH
CG482_RS05590	COG2357	RelA SpoT domain protein
CG482_RS05600	COG0564	pseudouridine synthase activity
CG482_RS05610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG482_RS05615	COG0772	Belongs to the SEDS family
CG482_RS05660	COG1216	Glycosyl transferase, family 2
CG482_RS05680	COG0457	Tetratricopeptide repeat
CG482_RS05680	COG0463	Glycosyl transferase, family 2
CG482_RS05700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG482_RS05715	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG482_RS05740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CG482_RS05745	COG2382	esterase
CG482_RS05760	COG5492	domain, Protein
CG482_RS05765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS05780	COG1620	l-lactate permease
CG482_RS05785	COG5634	Uncharacterized conserved protein (DUF2278)
CG482_RS05825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG482_RS05830	COG0567	Dehydrogenase, E1 component
CG482_RS05840	COG0583	DNA-binding transcription factor activity
CG482_RS05845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG482_RS05850	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS05865	COG0196	riboflavin kinase activity
CG482_RS05870	COG3162	membrane
CG482_RS05875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS05880	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG482_RS05895	COG0457	Tetratricopeptide repeat
CG482_RS05955	COG0673	inositol 2-dehydrogenase activity
CG482_RS05985	COG0457	Tetratricopeptide repeat
CG482_RS05990	COG0582	viral genome integration into host DNA
CG482_RS06030	COG1686	Belongs to the peptidase S11 family
CG482_RS06035	COG0681	Belongs to the peptidase S26 family
CG482_RS06070	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS06080	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG482_RS06085	COG1177	transmembrane transport
CG482_RS06090	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CG482_RS06095	COG0671	phosphoesterase, PA-phosphatase related
CG482_RS06100	COG2409	Drug exporters of the RND superfamily
CG482_RS06110	COG0564	pseudouridine synthase activity
CG482_RS06120	COG2340	Cysteine-rich secretory protein family
CG482_RS06125	COG0247	lactate metabolic process
CG482_RS06130	COG0277	FAD linked oxidase domain protein
CG482_RS06135	COG3835	regulator
CG482_RS06145	COG0745	RESPONSE REGULATOR receiver
CG482_RS06150	COG5002	protein histidine kinase activity
CG482_RS06155	COG2186	Transcriptional regulator
CG482_RS06160	COG0247	lactate metabolic process
CG482_RS06165	COG1139	Iron-sulfur cluster binding protein
CG482_RS06170	COG1556	Lactate utilization protein
CG482_RS06175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CG482_RS06180	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_RS06190	COG2267	carboxylic ester hydrolase activity
CG482_RS06195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG482_RS06205	COG2116	formate transmembrane transporter activity
CG482_RS06210	COG0861	Integral membrane protein TerC family
CG482_RS06215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG482_RS06225	COG2030	dehydratase
CG482_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS06250	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG482_RS06255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG482_RS06270	COG1840	ABC-type Fe3 transport system, periplasmic component
CG482_RS06275	COG3842	ATPase activity
CG482_RS06285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG482_RS06290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG482_RS06295	COG1349	DNA-binding transcription factor activity
CG482_RS06300	COG0235	Class ii aldolase
CG482_RS06310	COG2861	carbohydrate metabolic process
CG482_RS06320	COG3852	Histidine kinase
CG482_RS06325	COG1846	Transcriptional regulator
CG482_RS06345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG482_RS06350	COG0720	synthase
CG482_RS06360	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG482_RS06365	COG4873	Protein conserved in bacteria
CG482_RS06375	COG0456	acetyltransferase
CG482_RS06395	COG1780	Probably involved in ribonucleotide reductase function
CG482_RS06415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG482_RS06420	COG1725	Transcriptional regulator
CG482_RS06425	COG1131	(ABC) transporter
CG482_RS06435	COG1131	(ABC) transporter
CG482_RS06440	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG482_RS06455	COG1522	sequence-specific DNA binding
CG482_RS06470	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG482_RS06475	COG2070	2-Nitropropane dioxygenase
CG482_RS06480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CG482_RS06490	COG1696	Membrane protein involved in D-alanine export
CG482_RS06495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG482_RS06510	COG0716	FMN binding
CG482_RS06535	COG1368	sulfuric ester hydrolase activity
CG482_RS06545	COG3173	Aminoglycoside phosphotransferase
CG482_RS06555	COG5609	conserved protein (DUF2294)
CG482_RS06560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG482_RS06565	COG3002	Belongs to the UPF0753 family
CG482_RS06570	COG0288	reversible hydration of carbon dioxide
CG482_RS06575	COG0534	Mate efflux family protein
CG482_RS06590	COG1846	Transcriptional regulator
CG482_RS06600	COG1301	dicarboxylic acid transport
CG482_RS06605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG482_RS06615	COG3874	Sporulation protein YtfJ
CG482_RS06640	COG0028	Belongs to the TPP enzyme family
CG482_RS06645	COG0440	acetolactate synthase activity
CG482_RS06650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG482_RS06655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG482_RS06665	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG482_RS06670	COG0066	3-isopropylmalate dehydratase activity
CG482_RS06680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG482_RS06690	COG0131	Imidazoleglycerol-phosphate dehydratase
CG482_RS06695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG482_RS06705	COG0107	imidazoleglycerol-phosphate synthase activity
CG482_RS06710	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG482_RS06715	COG0140	phosphoribosyl-ATP diphosphatase activity
CG482_RS06730	COG1183	phosphatidylcholine synthase activity
CG482_RS06735	COG1368	sulfuric ester hydrolase activity
CG482_RS06745	COG0019	diaminopimelate decarboxylase activity
CG482_RS06755	COG0175	sulfate reduction
CG482_RS06760	COG2046	Belongs to the sulfate adenylyltransferase family
CG482_RS06765	COG0529	Catalyzes the synthesis of activated sulfate
CG482_RS06770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG482_RS06790	COG1648	precorrin-2 dehydrogenase activity
CG482_RS06790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG482_RS06795	COG0733	neurotransmitter:sodium symporter activity
CG482_RS06810	COG3557	Belongs to the UPF0374 family
CG482_RS06815	COG1757	Na H antiporter
CG482_RS06830	COG4758	membrane
CG482_RS06835	COG4585	Histidine kinase
CG482_RS06840	COG2197	response regulator
CG482_RS06845	COG1114	Component of the transport system for branched-chain amino acids
CG482_RS06850	COG0737	Belongs to the 5'-nucleotidase family
CG482_RS06850	COG1525	nuclease
CG482_RS06850	COG4085	toxin activity
CG482_RS06880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_RS06880	COG3711	transcriptional antiterminator
CG482_RS06885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_RS06885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_RS06885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_RS06905	COG2801	Transposase and inactivated derivatives
CG482_RS06925	COG0730	response to heat
CG482_RS06930	COG0306	phosphate transporter
CG482_RS06935	COG1392	Phosphate transport regulator
CG482_RS06940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_RS06950	COG3852	Histidine kinase
CG482_RS06955	COG1801	Protein of unknown function DUF72
CG482_RS06965	COG0582	viral genome integration into host DNA
CG482_RS06970	COG5002	protein histidine kinase activity
CG482_RS06975	COG0813	purine-nucleoside phosphorylase activity
CG482_RS06985	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CG482_RS06985	COG0392	lysyltransferase activity
CG482_RS07005	COG1686	Belongs to the peptidase S11 family
CG482_RS07010	COG2715	membrane protein required for spore maturation
CG482_RS07015	COG0700	Nucleoside recognition
CG482_RS07020	COG1187	pseudouridine synthase activity
CG482_RS07030	COG1333	cytochrome c biogenesis protein
CG482_RS07035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG482_RS07040	COG0745	RESPONSE REGULATOR receiver
CG482_RS07045	COG5002	protein histidine kinase activity
CG482_RS07050	COG2096	Adenosyltransferase
CG482_RS07065	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CG482_RS07070	COG1141	Ferredoxin
CG482_RS07080	COG0514	ATP-dependent DNA helicase (RecQ)
CG482_RS07085	COG1266	CAAX protease self-immunity
CG482_RS07095	COG1408	metallophosphoesterase
CG482_RS07110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CG482_RS07135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG482_RS07145	COG1304	FMN binding
CG482_RS07180	COG1160	GTP binding
CG482_RS07185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG482_RS07205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG482_RS07215	COG0302	gtp cyclohydrolase
CG482_RS07220	COG0142	geranyltranstransferase activity
CG482_RS07225	COG2226	methyltransferase
CG482_RS07230	COG0142	geranyltranstransferase activity
CG482_RS07240	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG482_RS07245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG482_RS07250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG482_RS07255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG482_RS07260	COG0457	Tetratricopeptide repeat
CG482_RS07265	COG5582	Belongs to the UPF0302 family
CG482_RS07280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG482_RS07290	COG4347	Protein of unknown function (DUF1405)
CG482_RS07305	COG2738	Putative neutral zinc metallopeptidase
CG482_RS07315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS07320	COG1694	Mazg nucleotide pyrophosphohydrolase
CG482_RS07325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG482_RS07330	COG1803	Methylglyoxal synthase
CG482_RS07335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG482_RS07340	COG0438	transferase activity, transferring glycosyl groups
CG482_RS07345	COG0617	tRNA 3'-terminal CCA addition
CG482_RS07355	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG482_RS07360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG482_RS07365	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CG482_RS07370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG482_RS07370	COG1199	ATP-dependent helicase activity
CG482_RS07390	COG3935	DnaD domain protein
CG482_RS07395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CG482_RS07405	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG482_RS07405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_RS07410	COG3331	DNA recombination
CG482_RS07445	COG4474	Belongs to the UPF0398 family
CG482_RS07450	COG3599	regulation of cell shape
CG482_RS07460	COG0116	Belongs to the methyltransferase superfamily
CG482_RS07470	COG1199	ATP-dependent helicase activity
CG482_RS07475	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CG482_RS07485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG482_RS07490	COG2233	PERMEase
CG482_RS07495	COG2311	Membrane
CG482_RS07500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CG482_RS07510	COG0456	acetyltransferase
CG482_RS07550	COG3766	membrane
CG482_RS07560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_RS07565	COG1733	regulation of RNA biosynthetic process
CG482_RS07585	COG0328	RNA-DNA hybrid ribonuclease activity
CG482_RS07615	COG1278	Cold shock
CG482_RS07625	COG3162	membrane
CG482_RS07630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS07635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG482_RS07640	COG0475	glutathione-regulated potassium exporter activity
CG482_RS07645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG482_RS07650	COG2323	membrane
CG482_RS07655	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CG482_RS07680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG482_RS07690	COG2201	protein-glutamate methylesterase activity
CG482_RS07695	COG0643	Histidine kinase
CG482_RS07695	COG2198	Histidine kinase
CG482_RS07700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_RS07700	COG1776	CheC inhibitor of MCP methylation
CG482_RS07715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG482_RS07725	COG1728	Protein conserved in bacteria
CG482_RS07735	COG1256	bacterial-type flagellum assembly
CG482_RS07740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG482_RS07760	COG1815	bacterial-type flagellum-dependent cell motility
CG482_RS07765	COG1558	bacterial-type flagellum-dependent cell motility
CG482_RS07780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_RS07790	COG1157	protein secretion by the type III secretion system
CG482_RS07825	COG0835	chemotaxis
CG482_RS07825	COG0784	Response regulator, receiver
CG482_RS07835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG482_RS07840	COG0457	Tetratricopeptide repeat
CG482_RS07840	COG0463	Glycosyl transferase, family 2
CG482_RS07855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG482_RS07860	COG0741	lytic transglycosylase activity
CG482_RS07870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_RS07875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG482_RS07875	COG1776	CheC inhibitor of MCP methylation
CG482_RS07885	COG1338	Plays a role in the flagellum-specific transport system
CG482_RS07890	COG1987	bacterial-type flagellum assembly
CG482_RS07900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG482_RS07905	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG482_RS07910	COG1419	protein localization to endoplasmic reticulum
CG482_RS07915	COG4786	Flagellar basal body rod
CG482_RS07920	COG1136	(ABC) transporter
CG482_RS07920	COG0577	efflux transmembrane transporter activity
CG482_RS07950	COG1309	transcriptional regulator
CG482_RS07970	COG2814	Major facilitator Superfamily
CG482_RS08015	COG0367	asparagine synthase
CG482_RS08035	COG1802	Transcriptional regulator
CG482_RS08055	COG1757	Na H antiporter
CG482_RS08085	COG0534	Mate efflux family protein
CG482_RS08090	COG3340	Belongs to the peptidase S51 family
CG482_RS08095	COG2733	membrane
CG482_RS08105	COG1280	lysine exporter protein (LysE YggA)
CG482_RS08110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG482_RS08125	COG2502	aspartate--ammonia ligase
CG482_RS08130	COG1309	transcriptional regulator
CG482_RS08135	COG0109	protoheme IX farnesyltransferase activity
CG482_RS08165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG482_RS08170	COG0488	(ABC) transporter
CG482_RS08175	COG4166	transmembrane transport
CG482_RS08180	COG2223	nitrite transmembrane transporter activity
CG482_RS08185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG482_RS08190	COG2244	polysaccharide biosynthetic process
CG482_RS08195	COG0733	neurotransmitter:sodium symporter activity
CG482_RS08200	COG5566	PFAM Mor transcription activator
CG482_RS08210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG482_RS08215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG482_RS08225	COG0129	dihydroxy-acid dehydratase activity
CG482_RS08230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG482_RS08235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_RS08240	COG2814	Major facilitator Superfamily
CG482_RS08245	COG3384	dioxygenase
CG482_RS08265	COG0402	S-adenosylhomocysteine deaminase activity
CG482_RS08270	COG4166	transmembrane transport
CG482_RS08280	COG1914	H( )-stimulated, divalent metal cation uptake system
CG482_RS08285	COG1054	Belongs to the UPF0176 family
CG482_RS08295	COG0083	homoserine kinase activity
CG482_RS08305	COG2390	Transcriptional regulator
CG482_RS08310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG482_RS08325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG482_RS08335	COG1510	regulation of RNA biosynthetic process
CG482_RS08340	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS08345	COG1454	alcohol dehydrogenase
CG482_RS08360	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS08365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG482_RS08375	COG0628	permease
CG482_RS08390	COG0523	cobalamin synthesis protein
CG482_RS08415	COG1686	Belongs to the peptidase S11 family
CG482_RS08430	COG1388	LysM domain
CG482_RS08430	COG0791	NLP P60 protein
CG482_RS08435	COG0300	oxidoreductase activity
CG482_RS08445	COG0460	homoserine dehydrogenase
CG482_RS08455	COG0083	homoserine kinase activity
CG482_RS08460	COG1316	TRANSCRIPTIONal
CG482_RS08475	COG1285	pathogenesis
CG482_RS08480	COG1247	-acetyltransferase
CG482_RS08515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CG482_RS08520	COG0577	efflux transmembrane transporter activity
CG482_RS08525	COG2409	Drug exporters of the RND superfamily
CG482_RS08530	COG1404	Belongs to the peptidase S8 family
CG482_RS08545	COG0840	transmembrane signaling receptor activity
CG482_RS08565	COG0783	Belongs to the Dps family
CG482_RS08585	COG0523	cobalamin synthesis protein
CG482_RS08595	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG482_RS08610	COG1902	pentaerythritol trinitrate reductase activity
CG482_RS08615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG482_RS08625	COG4166	transmembrane transport
CG482_RS08630	COG0346	lactoylglutathione lyase activity
CG482_RS08640	COG5337	Spore coat protein CotH
CG482_RS08645	COG1051	belongs to the nudix hydrolase family
CG482_RS08650	COG0586	Pfam SNARE associated Golgi protein
CG482_RS08655	COG2244	polysaccharide biosynthetic process
CG482_RS08665	COG0701	Predicted permease
CG482_RS08670	COG3689	TIGRFAM TIGR03943 family protein
CG482_RS08675	COG1607	acyl-coa hydrolase
CG482_RS08685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG482_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS08705	COG2839	Protein conserved in bacteria
CG482_RS08710	COG1253	flavin adenine dinucleotide binding
CG482_RS08750	COG0860	N-Acetylmuramoyl-L-alanine amidase
CG482_RS08760	COG1876	peptidase activity
CG482_RS08810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG482_RS08815	COG1819	glycosyl
CG482_RS08820	COG1819	glycosyl
CG482_RS08825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_RS08870	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG482_RS08910	COG3874	Sporulation protein YtfJ
CG482_RS08935	COG2226	methyltransferase
CG482_RS08960	COG0386	Belongs to the glutathione peroxidase family
CG482_RS08990	COG0640	Transcriptional regulator
CG482_RS08995	COG0798	PFAM Bile acid sodium symporter
CG482_RS09000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG482_RS09045	COG1418	mRNA catabolic process
CG482_RS09050	COG0488	(ABC) transporter
CG482_RS09060	COG0629	single-stranded DNA binding
CG482_RS09065	COG1413	lyase activity
CG482_RS09080	COG2521	methyltransferase
CG482_RS09080	COG2136	Putative SAM-dependent methyltransferase
CG482_RS09085	COG0018	arginyl-trna synthetase
CG482_RS09095	COG0733	neurotransmitter:sodium symporter activity
CG482_RS09100	COG0596	Alpha beta hydrolase
CG482_RS09120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_RS09125	COG0477	Major facilitator Superfamily
CG482_RS09145	COG1454	alcohol dehydrogenase
CG482_RS09160	COG0456	acetyltransferase
CG482_RS09165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG482_RS09175	COG1131	(ABC) transporter
CG482_RS09180	COG4473	ABC transporter
CG482_RS09195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG482_RS09200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG482_RS09210	COG0768	penicillin binding
CG482_RS09220	COG0204	Acyl-transferase
CG482_RS09230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG482_RS09235	COG0805	protein transport
CG482_RS09245	COG1307	EDD domain protein, DegV family
CG482_RS09255	COG1999	signal sequence binding
CG482_RS09260	COG0071	Belongs to the small heat shock protein (HSP20) family
CG482_RS09265	COG0367	asparagine synthase
CG482_RS09280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG482_RS09305	COG0071	Belongs to the small heat shock protein (HSP20) family
CG482_RS09315	COG1737	Transcriptional regulator
CG482_RS09320	COG1070	Carbohydrate kinase
CG482_RS09330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CG482_RS09385	COG1151	hydroxylamine reductase activity
CG482_RS09395	COG1253	flavin adenine dinucleotide binding
CG482_RS09400	COG5506	Protein of unknown function (DUF1694)
CG482_RS09420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG482_RS09425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CG482_RS09430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG482_RS09435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG482_RS09440	COG0456	acetyltransferase
CG482_RS09445	COG3829	transcription factor binding
CG482_RS09455	COG1509	lysine 2,3-aminomutase activity
CG482_RS09465	COG4479	Belongs to the UPF0346 family
CG482_RS09470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG482_RS09500	COG1357	PFAM Pentapeptide repeats (8 copies)
CG482_RS09500	COG0515	serine threonine protein kinase
CG482_RS09510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG482_RS09515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_RS09565	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CG482_RS09575	COG0726	polysaccharide deacetylase
CG482_RS09580	COG1408	metallophosphoesterase
CG482_RS09585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG482_RS09590	COG2323	membrane
CG482_RS09595	COG0671	phosphoesterase, PA-phosphatase related
CG482_RS09605	COG1280	lysine exporter protein (LysE YggA)
CG482_RS09610	COG3403	YqcI/YcgG family
CG482_RS09640	COG4499	WXG100 protein secretion system (Wss), protein YukC
CG482_RS09640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_RS09650	COG0372	Belongs to the citrate synthase family
CG482_RS09655	COG2079	MmgE PrpD family protein
CG482_RS09660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CG482_RS09665	COG1960	acyl-CoA dehydrogenase activity
CG482_RS09670	COG2084	Dehydrogenase
CG482_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS09685	COG1280	lysine exporter protein (LysE YggA)
CG482_RS09710	COG0420	3'-5' exonuclease activity
CG482_RS09715	COG0419	ATPase involved in DNA repair
CG482_RS09720	COG3104	oligopeptide transport
CG482_RS09755	COG1131	(ABC) transporter
CG482_RS09775	COG1131	(ABC) transporter
CG482_RS09780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG482_RS09800	COG1942	4-Oxalocrotonate Tautomerase
CG482_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS09820	COG1169	isochorismate synthase
CG482_RS09825	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG482_RS09830	COG1535	isochorismatase
CG482_RS09830	COG3433	isochorismatase activity
CG482_RS09835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG482_RS09840	COG3251	PFAM MbtH domain protein
CG482_RS09845	COG2814	Major facilitator Superfamily
CG482_RS09910	COG0776	regulation of translation
CG482_RS09925	COG2329	Antibiotic biosynthesis monooxygenase
CG482_RS09970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CG482_RS09975	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CG482_RS09980	COG0667	Aldo Keto reductase
CG482_RS10000	COG0010	Belongs to the arginase family
CG482_RS10010	COG1132	(ABC) transporter
CG482_RS10015	COG1132	(ABC) transporter
CG482_RS10045	COG1649	PFAM Uncharacterised BCR, COG1649
CG482_RS10065	COG2971	BadF BadG BcrA BcrD
CG482_RS10085	COG0588	phosphoglycerate mutase activity
CG482_RS10120	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG482_RS10130	COG1960	acyl-CoA dehydrogenase activity
CG482_RS10135	COG0439	Biotin carboxylase
CG482_RS10140	COG0511	ligase activity, forming carbon-carbon bonds
CG482_RS10145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG482_RS10150	COG1024	Enoyl-CoA hydratase
CG482_RS10155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG482_RS10160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG482_RS10170	COG1216	Glycosyl transferase, family 2
CG482_RS10175	COG0640	Transcriptional regulator
CG482_RS10190	COG1686	Belongs to the peptidase S11 family
CG482_RS10195	COG5002	protein histidine kinase activity
CG482_RS10225	COG0789	Transcriptional regulator
CG482_RS10250	COG0745	RESPONSE REGULATOR receiver
CG482_RS10270	COG2002	toxin-antitoxin pair type II binding
CG482_RS10290	COG0693	protein deglycase activity
CG482_RS10295	COG0201	protein transport
CG482_RS10320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG482_RS10325	COG0322	excinuclease ABC activity
CG482_RS10330	COG2318	DinB family
CG482_RS10340	COG4667	esterase of the alpha-beta hydrolase superfamily
CG482_RS10385	COG2223	nitrite transmembrane transporter activity
CG482_RS10430	COG1216	Glycosyl transferase, family 2
CG482_RS10445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_RS10450	COG1279	arginine transmembrane transporter activity
CG482_RS10485	COG1794	racemase activity, acting on amino acids and derivatives
CG482_RS10495	COG2828	Protein conserved in bacteria
CG482_RS10500	COG5002	protein histidine kinase activity
CG482_RS10505	COG0561	phosphatase activity
CG482_RS10525	COG2124	cytochrome p450
CG482_RS10570	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG482_RS10600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CG482_RS10605	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS10610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_RS10620	COG2959	enzyme of heme biosynthesis
CG482_RS10650	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CG482_RS10655	COG3844	kynureninase activity
CG482_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS10675	COG4176	ABC-type proline glycine betaine transport system permease component
CG482_RS10680	COG4175	Glycine betaine
CG482_RS10680	COG0517	IMP dehydrogenase activity
CG482_RS10710	COG2153	protein acetylation
CG482_RS10735	COG0514	ATP-dependent DNA helicase (RecQ)
CG482_RS10755	COG4637	Psort location Cytoplasmic, score
CG482_RS10760	COG1227	inorganic diphosphatase activity
CG482_RS10770	COG3397	chitin binding
CG482_RS10810	COG4166	transmembrane transport
CG482_RS10820	COG4948	Mandelate Racemase Muconate Lactonizing
CG482_RS10890	COG1307	EDD domain protein, DegV family
CG482_RS10955	COG2261	transglycosylase associated protein
CG482_RS10975	COG2826	transposase and inactivated derivatives, IS30 family
CG482_RS10990	COG0436	Aminotransferase
CG482_RS11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_RS11040	COG0628	permease
CG482_RS11055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG482_RS11060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_RS11065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG482_RS11080	COG2746	aminoglycoside 3-N-acetyltransferase activity
CG482_RS11095	COG0456	acetyltransferase
CG482_RS11095	COG0454	-acetyltransferase
CG482_RS11120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_RS11125	COG1368	sulfuric ester hydrolase activity
CG482_RS11130	COG0488	(ABC) transporter
CG482_RS11135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG482_RS11135	COG1605	Chorismate mutase
CG482_RS11155	COG0346	lactoylglutathione lyase activity
CG482_RS11165	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CG482_RS11170	COG1518	maintenance of DNA repeat elements
CG482_RS11210	COG2329	Antibiotic biosynthesis monooxygenase
CG482_RS11225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_RS11250	COG0494	nUDIX hydrolase
CG482_RS11265	COG0456	acetyltransferase
CG482_RS11270	COG0477	Major facilitator Superfamily
CG482_RS11285	COG0697	spore germination
CG482_RS11290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_RS11300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CG482_RS11315	COG0730	response to heat
CG482_RS11325	COG0833	amino acid
CG482_RS11345	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CG482_RS11360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG482_RS11365	COG1984	allophanate hydrolase subunit 2
CG482_RS11370	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG482_RS11375	COG1414	Transcriptional regulator
CG482_RS11390	COG1960	acyl-CoA dehydrogenase activity
CG482_RS11405	COG3314	Sporulation integral membrane protein YlbJ
CG482_RS11420	COG0346	lactoylglutathione lyase activity
CG482_RS11430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG482_RS11435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG482_RS11440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG482_RS11445	COG0438	transferase activity, transferring glycosyl groups
CG482_RS11460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_RS11465	COG0438	transferase activity, transferring glycosyl groups
CG482_RS11470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_RS11485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG482_RS11505	COG4851	CamS sex pheromone cAM373 precursor
CG482_RS11600	COG0477	Major facilitator Superfamily
CG482_RS11615	COG1846	Transcriptional regulator
CG482_RS11620	COG2814	Major facilitator Superfamily
CG482_RS11630	COG2031	fatty acid transporter
CG482_RS11660	COG1122	ATPase activity
CG482_RS11665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG482_RS11685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG482_RS11700	COG1131	(ABC) transporter
CG482_RS11720	COG2365	Tyrosine phosphatase family
CG482_RS11760	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CG482_RS11765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS11770	COG0579	oxidoreductase
CG482_RS11775	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CG482_RS11785	COG1253	flavin adenine dinucleotide binding
CG482_RS11790	COG0789	Transcriptional regulator
CG482_RS11795	COG3813	Protein conserved in bacteria
CG482_RS11810	COG0384	phenazine biosynthesis protein PhzF
CG482_RS11870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG482_RS11910	COG1136	(ABC) transporter
CG482_RS11910	COG0577	efflux transmembrane transporter activity
CG482_RS11975	COG1136	(ABC) transporter
CG482_RS11975	COG0577	efflux transmembrane transporter activity
CG482_RS12025	COG2072	flavoprotein involved in K transport
CG482_RS12055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG482_RS12060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG482_RS12070	COG1193	negative regulation of DNA recombination
CG482_RS12080	COG1164	Oligoendopeptidase f
CG482_RS12100	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_RS12105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_RS12135	COG3397	chitin binding
CG482_RS12145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG482_RS12150	COG0277	FAD linked oxidase domain protein
CG482_RS12155	COG1285	pathogenesis
CG482_RS12160	COG2720	vancomycin resistance protein
CG482_RS12200	COG4824	toxin secretion phage lysis holin
CG482_RS12310	COG0270	DNA (cytosine-5-)-methyltransferase activity
CG482_RS12355	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG482_RS12375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_RS12375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_RS12445	COG1484	DNA-dependent DNA replication
CG482_RS12485	COG0582	viral genome integration into host DNA
CG482_RS12510	COG1278	Cold shock
CG482_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS12525	COG0165	Argininosuccinate lyase
CG482_RS12540	COG3409	Peptidoglycan-binding domain 1 protein
CG482_RS12555	COG4145	pantothenate transmembrane transporter activity
CG482_RS12565	COG1012	belongs to the aldehyde dehydrogenase family
CG482_RS12580	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CG482_RS12585	COG2962	Rard protein
CG482_RS12620	COG2226	methyltransferase
CG482_RS12625	COG4166	transmembrane transport
CG482_RS12630	COG4166	transmembrane transport
CG482_RS12635	COG1301	dicarboxylic acid transport
CG482_RS12645	COG0673	inositol 2-dehydrogenase activity
CG482_RS12650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG482_RS12655	COG0187	DNA topoisomerase II activity
CG482_RS12665	COG1832	CoA-binding protein
CG482_RS12670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG482_RS12675	COG0745	RESPONSE REGULATOR receiver
CG482_RS12690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG482_RS12695	COG4841	protein insertion into membrane
CG482_RS12700	COG0824	Thioesterase
CG482_RS12730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_RS12735	COG3655	Transcriptional regulator
CG482_RS12755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG482_RS12795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG482_RS12800	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_RS12830	COG0457	Tetratricopeptide repeat
CG482_RS12915	COG2826	transposase and inactivated derivatives, IS30 family
CG482_RS12930	COG0534	Mate efflux family protein
CG482_RS12960	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG482_RS12970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS12980	COG5002	protein histidine kinase activity
CG482_RS12985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CG482_RS12990	COG0010	Belongs to the arginase family
CG482_RS12995	COG1228	amidohydrolase
CG482_RS13000	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CG482_RS13005	COG2986	histidine ammonia-lyase
CG482_RS13030	COG4846	Membrane protein involved in cytochrome C biogenesis
CG482_RS13035	COG0785	Cytochrome C biogenesis protein
CG482_RS13045	COG1473	amidohydrolase
CG482_RS13050	COG0583	DNA-binding transcription factor activity
CG482_RS13055	COG1380	Effector of murein hydrolase LrgA
CG482_RS13060	COG1346	cytolysis
CG482_RS13065	COG4187	Peptidase family M20/M25/M40
CG482_RS13075	COG0833	amino acid
CG482_RS13085	COG0730	response to heat
CG482_RS13095	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG482_RS13095	COG3409	Peptidoglycan-binding domain 1 protein
CG482_RS13110	COG1132	(ABC) transporter
CG482_RS13115	COG1132	(ABC) transporter
CG482_RS13120	COG3763	UPF0154 protein
CG482_RS13135	COG3639	organic phosphonate transmembrane transporter activity
CG482_RS13140	COG3639	organic phosphonate transmembrane transporter activity
CG482_RS13155	COG0737	Belongs to the 5'-nucleotidase family
CG482_RS13160	COG4224	UPF0291 protein
CG482_RS13165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG482_RS13170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG482_RS13185	COG1695	Transcriptional regulator
CG482_RS13225	COG3328	transposase activity
CG482_RS13230	COG3328	transposase activity
CG482_RS13245	COG1598	PFAM Uncharacterised protein family UPF0150
CG482_RS13255	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CG482_RS13280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG482_RS13300	COG0730	response to heat
CG482_RS13385	COG4824	toxin secretion phage lysis holin
CG482_RS13465	COG3728	DNA packaging
CG482_RS13475	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG482_RS13605	COG0582	viral genome integration into host DNA
CG482_RS13610	COG0174	glutamine synthetase
CG482_RS13615	COG0789	Transcriptional regulator
CG482_RS13620	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CG482_RS13625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG482_RS13630	COG2860	membrane
CG482_RS13635	COG0464	growth
CG482_RS13650	COG1923	regulation of RNA biosynthetic process
CG482_RS13655	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG482_RS13665	COG3584	3D domain protein
CG482_RS13665	COG1388	LysM domain
CG482_RS13670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_RS13670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CG482_RS13670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_RS13675	COG1105	Belongs to the carbohydrate kinase PfkB family
CG482_RS13680	COG1349	DNA-binding transcription factor activity
CG482_RS13685	COG2322	membrane
CG482_RS13710	COG2116	formate transmembrane transporter activity
CG482_RS13720	COG1937	Protein conserved in bacteria
CG482_RS13725	COG2819	hydrolase of the alpha beta superfamily
CG482_RS13730	COG1120	ATPase activity
CG482_RS13735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS13740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS13745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG482_RS13750	COG2706	6-phosphogluconolactonase activity
CG482_RS13755	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG482_RS13765	COG0346	lactoylglutathione lyase activity
CG482_RS13780	COG1113	amino acid transport
CG482_RS13805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG482_RS13810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG482_RS13820	COG4550	Control of competence regulator ComK, YlbF/YmcA
CG482_RS13825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG482_RS13830	COG1013	pyruvate-flavodoxin oxidoreductase activity
CG482_RS13835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CG482_RS13835	COG0674	pyruvate-flavodoxin oxidoreductase activity
CG482_RS13845	COG2359	stage V sporulation protein S
CG482_RS13850	COG1692	metallophosphoesterase
CG482_RS13855	COG1418	mRNA catabolic process
CG482_RS13860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG482_RS13865	COG1058	Belongs to the CinA family
CG482_RS13865	COG1546	Belongs to the CinA family
CG482_RS13870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG482_RS13875	COG1426	Protein conserved in bacteria
CG482_RS13900	COG0612	Peptidase, M16
CG482_RS13905	COG0612	Peptidase, M16
CG482_RS13910	COG1079	Belongs to the binding-protein-dependent transport system permease family
CG482_RS13915	COG4603	Belongs to the binding-protein-dependent transport system permease family
CG482_RS13920	COG3845	ABC transporter
CG482_RS13925	COG1744	ABC transporter substrate-binding protein PnrA-like
CG482_RS13930	COG2188	Transcriptional regulator
CG482_RS13935	COG1674	ftsk spoiiie
CG482_RS13950	COG0740	serine-type endopeptidase activity
CG482_RS13975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG482_RS13995	COG0527	aspartate kinase activity
CG482_RS14000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG482_RS14005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG482_RS14010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG482_RS14015	COG1873	PFAM PRC-barrel domain
CG482_RS14020	COG0612	Peptidase, M16
CG482_RS14025	COG0726	polysaccharide deacetylase
CG482_RS14030	COG1185	polyribonucleotide nucleotidyltransferase activity
CG482_RS14040	COG0196	riboflavin kinase activity
CG482_RS14045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG482_RS14050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG482_RS14055	COG1550	Protein conserved in bacteria
CG482_RS14060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG482_RS14065	COG1358	cellular component organization or biogenesis
CG482_RS14070	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CG482_RS14075	COG0195	Participates in both transcription termination and antitermination
CG482_RS14080	COG0779	Required for maturation of 30S ribosomal subunits
CG482_RS14090	COG0442	prolyl-tRNA aminoacylation
CG482_RS14095	COG0750	zinc metalloprotease
CG482_RS14105	COG4589	Belongs to the CDS family
CG482_RS14115	COG0233	cytoplasmic translational termination
CG482_RS14120	COG0528	UMP kinase activity
CG482_RS14125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG482_RS14130	COG0052	Belongs to the universal ribosomal protein uS2 family
CG482_RS14135	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CG482_RS14140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG482_RS14145	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG482_RS14150	COG4974	Belongs to the 'phage' integrase family
CG482_RS14155	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CG482_RS14160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG482_RS14165	COG0758	DNA mediated transformation
CG482_RS14170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG482_RS14175	COG0045	succinate-CoA ligase (ADP-forming) activity
CG482_RS14180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG482_RS14195	COG0335	large ribosomal subunit rRNA binding
CG482_RS14200	COG0336	Belongs to the RNA methyltransferase TrmD family
CG482_RS14205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG482_RS14210	COG1837	Belongs to the UPF0109 family
CG482_RS14215	COG0228	four-way junction DNA binding
CG482_RS14220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG482_RS14225	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CG482_RS14230	COG0552	protein localization to endoplasmic reticulum
CG482_RS14235	COG1196	nuclear chromosome segregation
CG482_RS14240	COG0571	ribonuclease III activity
CG482_RS14245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG482_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS14255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG482_RS14260	COG0416	fatty acid biosynthetic process
CG482_RS14265	COG1349	DNA-binding transcription factor activity
CG482_RS14265	COG2050	protein possibly involved in aromatic compounds catabolism
CG482_RS14270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG482_RS14275	COG1461	Dihydroxyacetone kinase
CG482_RS14280	COG1302	Protein conserved in bacteria
CG482_RS14285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG482_RS14295	COG1564	THIamine pyrophosphokinase
CG482_RS14300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CG482_RS14305	COG1162	GTPase activity
CG482_RS14310	COG0515	serine threonine protein kinase
CG482_RS14310	COG2815	serine threonine protein kinase
CG482_RS14315	COG0631	protein serine/threonine phosphatase activity
CG482_RS14320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG482_RS14325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG482_RS14325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG482_RS14330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG482_RS14335	COG0242	peptide deformylase activity
CG482_RS14340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CG482_RS14345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG482_RS14350	COG1758	RNA polymerase activity
CG482_RS14365	COG1561	YicC-like family, N-terminal region
CG482_RS14370	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CG482_RS14395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG482_RS14400	COG0284	orotidine-5'-phosphate decarboxylase activity
CG482_RS14405	COG0167	dihydroorotate dehydrogenase activity
CG482_RS14410	COG0543	2 iron, 2 sulfur cluster binding
CG482_RS14415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG482_RS14425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CG482_RS14430	COG0540	Belongs to the ATCase OTCase family
CG482_RS14440	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CG482_RS14450	COG0564	pseudouridine synthase activity
CG482_RS14455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG482_RS14465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG482_RS14470	COG3599	regulation of cell shape
CG482_RS14475	COG2302	S4 RNA-binding domain
CG482_RS14480	COG0762	integral membrane protein
CG482_RS14485	COG1799	cell septum assembly
CG482_RS14490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG482_RS14500	COG1873	PFAM PRC-barrel domain
CG482_RS14505	COG1191	sigma factor activity
CG482_RS14510	COG1191	sigma factor activity
CG482_RS14520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG482_RS14525	COG0849	cell division
CG482_RS14530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG482_RS14540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG482_RS14545	COG0772	Belongs to the SEDS family
CG482_RS14550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG482_RS14555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG482_RS14560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG482_RS14565	COG0768	penicillin binding
CG482_RS14570	COG0768	penicillin binding
CG482_RS14575	COG4839	cell division protein FtsL
CG482_RS14580	COG0275	rRNA processing
CG482_RS14585	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CG482_RS14590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CG482_RS14595	COG0454	-acetyltransferase
CG482_RS14605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CG482_RS14610	COG1399	metal-binding, possibly nucleic acid-binding protein
CG482_RS14720	COG4626	Terminase
CG482_RS14720	COG1802	Transcriptional regulator
CG482_RS14805	COG0756	dUTP diphosphatase activity
CG482_RS14835	COG3723	Recombinational DNA repair protein, rece pathway
CG482_RS14845	COG5377	YqaJ viral recombinase family
CG482_RS14885	COG0582	viral genome integration into host DNA
CG482_RS14890	COG1323	Belongs to the UPF0348 family
CG482_RS14895	COG3480	Lon protease (S16) C-terminal proteolytic domain
CG482_RS14900	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG482_RS14905	COG3314	Sporulation integral membrane protein YlbJ
CG482_RS14910	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG482_RS14915	COG0742	ribosomal rna small subunit methyltransferase
CG482_RS14925	COG4471	UPF0298 protein
CG482_RS14930	COG3679	Belongs to the UPF0342 family
CG482_RS14935	COG0406	alpha-ribazole phosphatase activity
CG482_RS14950	COG2340	Cysteine-rich secretory protein family
CG482_RS14960	COG3336	cytochrome c oxidase
CG482_RS14985	COG0109	protoheme IX farnesyltransferase activity
CG482_RS14990	COG1612	heme a metabolic process
CG482_RS14995	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CG482_RS15005	COG0772	Belongs to the SEDS family
CG482_RS15010	COG4838	Belongs to the UPF0358 family
CG482_RS15015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG482_RS15020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CG482_RS15030	COG4896	Protein conserved in bacteria
CG482_RS15045	COG1217	gtp-binding protein TYPA
CG482_RS15055	COG0483	inositol monophosphate 1-phosphatase activity
CG482_RS15065	COG4493	Belongs to the UPF0637 family
CG482_RS15070	COG4476	Belongs to the UPF0223 family
CG482_RS15075	COG1982	Orn Lys Arg decarboxylase major
CG482_RS15115	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG482_RS15125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG482_RS15140	COG0561	phosphatase activity
CG482_RS15150	COG5503	Protein of unknown function (DUF1447)
CG482_RS15155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CG482_RS15160	COG0569	domain protein
CG482_RS15170	COG1473	amidohydrolase
CG482_RS15175	COG2171	N-acyltransferase activity
CG482_RS15180	COG0583	DNA-binding transcription factor activity
CG482_RS15185	COG0517	IMP dehydrogenase activity
CG482_RS15195	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CG482_RS15205	COG4703	Protein of unknown function (DUF1797)
CG482_RS15220	COG2200	EAL domain
CG482_RS15225	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS15230	COG1408	metallophosphoesterase
CG482_RS15240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG482_RS15280	COG2814	Major facilitator Superfamily
CG482_RS15285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG482_RS15295	COG3209	COG3209 Rhs family protein
CG482_RS15305	COG2205	protein histidine kinase activity
CG482_RS15315	COG0436	Aminotransferase
CG482_RS15320	COG1609	Transcriptional regulator
CG482_RS15355	COG0183	Belongs to the thiolase family
CG482_RS15385	COG1695	Transcriptional regulator
CG482_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS15400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CG482_RS15405	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CG482_RS15410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG482_RS15415	COG0436	Aminotransferase
CG482_RS15420	COG1850	ribulose-bisphosphate carboxylase activity
CG482_RS15425	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CG482_RS15430	COG0235	Class ii aldolase
CG482_RS15435	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CG482_RS15450	COG2084	Dehydrogenase
CG482_RS15465	COG0778	Nitroreductase
CG482_RS15490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG482_RS15490	COG1263	PTS System
CG482_RS15490	COG2190	(PTS) system
CG482_RS15495	COG3711	transcriptional antiterminator
CG482_RS15505	COG2188	Transcriptional regulator
CG482_RS15510	COG0363	glucosamine-6-phosphate deaminase activity
CG482_RS15525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG482_RS15530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG482_RS15540	COG1547	Domain of unknown function (DUF309)
CG482_RS15550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG482_RS15555	COG4086	secreted protein
CG482_RS15560	COG0561	phosphatase activity
CG482_RS15565	COG0697	spore germination
CG482_RS15580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG482_RS15605	COG0733	neurotransmitter:sodium symporter activity
CG482_RS15615	COG2172	sigma factor antagonist activity
CG482_RS15625	COG1686	Belongs to the peptidase S11 family
CG482_RS15635	COG1725	Transcriptional regulator
CG482_RS15640	COG1131	(ABC) transporter
CG482_RS15660	COG1846	Transcriptional regulator
CG482_RS15675	COG0598	Magnesium transport protein CorA
CG482_RS15700	COG4974	Belongs to the 'phage' integrase family
CG482_RS15710	COG0735	belongs to the Fur family
CG482_RS15715	COG1300	Membrane
CG482_RS15735	COG0667	Aldo Keto reductase
CG482_RS15740	COG0656	L-ascorbic acid biosynthetic process
CG482_RS15745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CG482_RS15745	COG0456	acetyltransferase
CG482_RS15755	COG0737	Belongs to the 5'-nucleotidase family
CG482_RS15755	COG1525	nuclease
CG482_RS15755	COG4085	toxin activity
CG482_RS15765	COG0596	Alpha beta hydrolase
CG482_RS15770	COG2056	Na+-H+ antiporter family
CG482_RS15775	COG1609	Transcriptional regulator
CG482_RS15780	COG0456	acetyltransferase
CG482_RS15785	COG1073	alpha beta
CG482_RS15800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG482_RS15800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG482_RS15805	COG0307	riboflavin synthase, alpha
CG482_RS15810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG482_RS15810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG482_RS15825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG482_RS15830	COG4106	trans-aconitate 2-methyltransferase activity
CG482_RS15835	COG0596	Alpha beta hydrolase
CG482_RS15840	COG0156	8-amino-7-oxononanoate synthase activity
CG482_RS15850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG482_RS15860	COG1757	Na H antiporter
CG482_RS15865	COG0737	Belongs to the 5'-nucleotidase family
CG482_RS15890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG482_RS15900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG482_RS15910	COG0300	oxidoreductase activity
CG482_RS15915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_RS15920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG482_RS15925	COG1760	l-serine dehydratase
CG482_RS15930	COG1760	l-serine dehydratase
CG482_RS15940	COG1234	tRNA 3'-trailer cleavage
CG482_RS15960	COG2195	Cleaves the N-terminal amino acid of tripeptides
CG482_RS15965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG482_RS15980	COG1376	ErfK ybiS ycfS ynhG family protein
CG482_RS15985	COG4129	membrane
CG482_RS15990	COG1126	abc transporter atp-binding protein
CG482_RS15995	COG0765	amino acid transport
CG482_RS16000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG482_RS16015	COG2816	NAD+ diphosphatase activity
CG482_RS16020	COG0772	Belongs to the SEDS family
CG482_RS16030	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG482_RS16035	COG0022	dehydrogenase e1 component
CG482_RS16040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG482_RS16045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG482_RS16050	COG3426	butyrate kinase activity
CG482_RS16060	COG0280	phosphate acetyltransferase
CG482_RS16070	COG3290	protein histidine kinase activity
CG482_RS16070	COG3829	transcription factor binding
CG482_RS16080	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_RS16085	COG3093	addiction module antidote protein HigA
CG482_RS16090	COG0745	RESPONSE REGULATOR receiver
CG482_RS16105	COG0750	zinc metalloprotease
CG482_RS16110	COG0497	DNA recombination
CG482_RS16120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG482_RS16125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG482_RS16135	COG1722	exodeoxyribonuclease VII activity
CG482_RS16140	COG1570	exodeoxyribonuclease VII activity
CG482_RS16145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG482_RS16150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG482_RS16155	COG1302	Protein conserved in bacteria
CG482_RS16160	COG0439	Biotin carboxylase
CG482_RS16165	COG0511	ligase activity, forming carbon-carbon bonds
CG482_RS16210	COG3854	ATPases associated with a variety of cellular activities
CG482_RS16230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG482_RS16235	COG0006	proline dipeptidase activity
CG482_RS16240	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG482_RS16250	COG3872	metal-dependent enzyme
CG482_RS16260	COG1321	iron dependent repressor
CG482_RS16275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG482_RS16285	COG1609	Transcriptional regulator
CG482_RS16295	COG2076	Multidrug Resistance protein
CG482_RS16300	COG2076	Multidrug Resistance protein
CG482_RS16320	COG1131	(ABC) transporter
CG482_RS16325	COG1725	Transcriptional regulator
CG482_RS16340	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG482_RS16345	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG482_RS16350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG482_RS16385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG482_RS16410	COG1459	type II secretion system
CG482_RS16435	COG4824	toxin secretion phage lysis holin
CG482_RS16515	COG3728	DNA packaging
CG482_RS16525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CG482_RS16635	COG1396	sequence-specific DNA binding
CG482_RS16650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG482_RS16685	COG1078	dGTPase activity
CG482_RS16705	COG1410	methionine synthase
CG482_RS16705	COG0646	methionine synthase
CG482_RS16710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG482_RS16710	COG0646	methionine synthase
CG482_RS16715	COG0626	cystathionine gamma-synthase activity
CG482_RS16720	COG0626	cystathionine gamma-synthase activity
CG482_RS16740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_RS16750	COG1940	carbohydrate kinase activity
CG482_RS16755	COG4483	Protein conserved in bacteria
CG482_RS16760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CG482_RS16765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG482_RS16775	COG0704	Plays a role in the regulation of phosphate uptake
CG482_RS16785	COG0581	inorganic phosphate transmembrane transporter activity
CG482_RS16790	COG0573	inorganic phosphate transmembrane transporter activity
CG482_RS16795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG482_RS16800	COG0768	penicillin binding
CG482_RS16805	COG0477	Major facilitator Superfamily
CG482_RS16810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG482_RS16830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG482_RS16835	COG0735	belongs to the Fur family
CG482_RS16840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG482_RS16845	COG1121	(ABC) transporter
CG482_RS16850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS16860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CG482_RS16875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG482_RS16880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CG482_RS16885	COG2384	SAM-dependent methyltransferase
CG482_RS16895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG482_RS16900	COG0358	DNA primase activity
CG482_RS16905	COG1671	Belongs to the UPF0178 family
CG482_RS16910	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG482_RS16915	COG0517	IMP dehydrogenase activity
CG482_RS16920	COG1381	Involved in DNA repair and RecF pathway recombination
CG482_RS16930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG482_RS16940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG482_RS16945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG482_RS16950	COG1480	7TM receptor with intracellular HD hydrolase
CG482_RS16955	COG1702	phosphate starvation-inducible protein PhoH
CG482_RS16970	COG1610	YqeY-like protein
CG482_RS16975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG482_RS16980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG482_RS16985	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CG482_RS16990	COG2264	protein methyltransferase activity
CG482_RS16995	COG0484	heat shock protein binding
CG482_RS17000	COG0443	Heat shock 70 kDa protein
CG482_RS17005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG482_RS17015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG482_RS17020	COG1733	regulation of RNA biosynthetic process
CG482_RS17025	COG0693	protein deglycase activity
CG482_RS17030	COG0481	GTPase activity
CG482_RS17040	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CG482_RS17045	COG0268	Binds directly to 16S ribosomal RNA
CG482_RS17050	COG1466	dna polymerase III delta subunit
CG482_RS17060	COG0658	competence protein
CG482_RS17060	COG2333	competence protein COMEC
CG482_RS17065	COG2131	deaminase
CG482_RS17070	COG1555	photosystem II stabilization
CG482_RS17070	COG1596	polysaccharide export
CG482_RS17075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG482_RS17080	COG2226	methyltransferase
CG482_RS17085	COG0799	negative regulation of ribosome biogenesis
CG482_RS17090	COG1713	HD superfamily hydrolase involved in NAD metabolism
CG482_RS17095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG482_RS17100	COG1534	Rna-binding protein
CG482_RS17105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG482_RS17110	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CG482_RS17115	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CG482_RS17125	COG0688	phosphatidylethanolamine metabolic process
CG482_RS17140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG482_RS17145	COG2357	RelA SpoT domain protein
CG482_RS17150	COG1785	Belongs to the alkaline phosphatase family
CG482_RS17155	COG0456	acetyltransferase
CG482_RS17160	COG2267	carboxylic ester hydrolase activity
CG482_RS17185	COG3186	Phenylalanine-4-hydroxylase
CG482_RS17190	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG482_RS17195	COG2514	catechol 2,3-dioxygenase activity
CG482_RS17200	COG2259	Doxx family
CG482_RS17220	COG1609	Transcriptional regulator
CG482_RS17230	COG0626	cystathionine gamma-synthase activity
CG482_RS17235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG482_RS17240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG482_RS17245	COG2226	methyltransferase
CG482_RS17265	COG0768	penicillin binding
CG482_RS17275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG482_RS17280	COG0572	uridine kinase
CG482_RS17285	COG0826	peptidase U32
CG482_RS17290	COG0826	peptidase U32
CG482_RS17295	COG4122	O-methyltransferase activity
CG482_RS17300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG482_RS17310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG482_RS17315	COG4472	Bacterial protein of unknown function (DUF965)
CG482_RS17320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG482_RS17325	COG0628	permease
CG482_RS17345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG482_RS17355	COG0482	sulfurtransferase activity
CG482_RS17360	COG1104	cysteine desulfurase activity
CG482_RS17365	COG1959	2 iron, 2 sulfur cluster binding
CG482_RS17370	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG482_RS17390	COG2207	Transcriptional regulator
CG482_RS17400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CG482_RS17405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG482_RS17410	COG0124	histidyl-tRNA synthetase
CG482_RS17430	COG1490	D-aminoacyl-tRNA deacylase activity
CG482_RS17435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CG482_RS17440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG482_RS17445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CG482_RS17445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG482_RS17450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG482_RS17455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG482_RS17455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CG482_RS17465	COG2244	polysaccharide biosynthetic process
CG482_RS17490	COG1862	Preprotein translocase
CG482_RS17495	COG0343	queuine tRNA-ribosyltransferase activity
CG482_RS17500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG482_RS17510	COG2255	four-way junction helicase activity
CG482_RS17515	COG0632	four-way junction helicase activity
CG482_RS17520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CG482_RS17540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CG482_RS17545	COG0157	Belongs to the NadC ModD family
CG482_RS17550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG482_RS17555	COG1104	cysteine desulfurase activity
CG482_RS17560	COG1827	regulation of RNA biosynthetic process
CG482_RS17565	COG2258	MOSC domain
CG482_RS17575	COG0077	Prephenate dehydratase
CG482_RS17580	COG0577	efflux transmembrane transporter activity
CG482_RS17585	COG0577	efflux transmembrane transporter activity
CG482_RS17590	COG1136	(ABC) transporter
CG482_RS17595	COG5002	protein histidine kinase activity
CG482_RS17600	COG0745	RESPONSE REGULATOR receiver
CG482_RS17610	COG3290	protein histidine kinase activity
CG482_RS17615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG482_RS17620	COG2868	ribosomal protein
CG482_RS17625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CG482_RS17630	COG1530	ribonuclease E activity
CG482_RS17635	COG1994	Peptidase M50
CG482_RS17640	COG0739	heme binding
CG482_RS17645	COG2894	cell division
CG482_RS17650	COG0850	regulation of cytokinetic process
CG482_RS17660	COG1792	Involved in formation and maintenance of cell shape
CG482_RS17665	COG1077	Cell shape determining protein MreB Mrl
CG482_RS17685	COG0424	maF-like protein
CG482_RS17695	COG0285	dihydrofolate synthase activity
CG482_RS17720	COG1388	LysM domain
CG482_RS17720	COG1388	LysM domain
CG482_RS17725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CG482_RS17730	COG0113	porphobilinogen synthase activity
CG482_RS17735	COG1587	Uroporphyrinogen-III synthase
CG482_RS17740	COG0181	hydroxymethylbilane synthase activity
CG482_RS17745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG482_RS17750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CG482_RS17755	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG482_RS17765	COG1067	ATP-dependent peptidase activity
CG482_RS17765	COG0470	DNA polymerase III
CG482_RS17770	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG482_RS17775	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_RS17800	COG3321	synthase
CG482_RS17800	COG4221	oxidoreductase activity
CG482_RS17800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG482_RS17800	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS17815	COG2409	Drug exporters of the RND superfamily
CG482_RS17815	COG1033	growth of symbiont in host cell
CG482_RS17825	COG1309	transcriptional regulator
CG482_RS17845	COG0622	Phosphoesterase
CG482_RS17855	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG482_RS17860	COG5401	PFAM Sporulation and spore germination
CG482_RS17870	COG2197	response regulator
CG482_RS17910	COG2197	response regulator
CG482_RS17920	COG1959	2 iron, 2 sulfur cluster binding
CG482_RS17925	COG1668	transmembrane transport
CG482_RS17930	COG4152	abc transporter atp-binding protein
CG482_RS17935	COG1360	Flagellar Motor Protein
CG482_RS17940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG482_RS17950	COG1876	peptidase activity
CG482_RS17960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CG482_RS17965	COG1053	succinate dehydrogenase
CG482_RS17970	COG2009	succinate dehydrogenase
CG482_RS17975	COG1719	4-vinyl reductase, 4VR
CG482_RS17990	COG3118	belongs to the thioredoxin family
CG482_RS17995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CG482_RS18000	COG2086	electron transfer activity
CG482_RS18005	COG1024	Enoyl-CoA hydratase
CG482_RS18010	COG1309	transcriptional regulator
CG482_RS18015	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_RS18025	COG2318	DinB family
CG482_RS18040	COG1131	(ABC) transporter
CG482_RS18045	COG2205	protein histidine kinase activity
CG482_RS18050	COG0745	RESPONSE REGULATOR receiver
CG482_RS18060	COG4895	conserved protein (DUF2196)
CG482_RS18065	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG482_RS18070	COG1114	Component of the transport system for branched-chain amino acids
CG482_RS18075	COG1187	pseudouridine synthase activity
CG482_RS18085	COG1193	negative regulation of DNA recombination
CG482_RS18090	COG1796	DNA polymerase
CG482_RS18090	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CG482_RS18095	COG1286	toxin biosynthetic process
CG482_RS18100	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CG482_RS18105	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG482_RS18125	COG0017	Asparaginyl-tRNA synthetase
CG482_RS18135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG482_RS18140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG482_RS18150	COG1418	mRNA catabolic process
CG482_RS18165	COG2814	Major facilitator Superfamily
CG482_RS18170	COG1566	PFAM secretion protein HlyD family protein
CG482_RS18175	COG1309	transcriptional regulator
CG482_RS18180	COG1363	Peptidase, m42
CG482_RS18190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG482_RS18195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG482_RS18205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG482_RS18215	COG1484	DNA-dependent DNA replication
CG482_RS18220	COG3611	Membrane attachment protein
CG482_RS18225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG482_RS18230	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CG482_RS18235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG482_RS18245	COG1971	Probably functions as a manganese efflux pump
CG482_RS18255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_RS18255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG482_RS18260	COG5002	protein histidine kinase activity
CG482_RS18265	COG0745	RESPONSE REGULATOR receiver
CG482_RS18275	COG0039	L-malate dehydrogenase activity
CG482_RS18280	COG0538	isocitrate dehydrogenase activity
CG482_RS18285	COG0372	Belongs to the citrate synthase family
CG482_RS18295	COG2707	UPF0756 membrane protein
CG482_RS18305	COG0628	permease
CG482_RS18310	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG482_RS18320	COG0205	6-phosphofructokinase activity
CG482_RS18325	COG0825	malonyl-CoA metabolic process
CG482_RS18330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG482_RS18335	COG1725	Transcriptional regulator
CG482_RS18340	COG0281	malic enzyme
CG482_RS18345	COG0587	DNA-directed DNA polymerase activity
CG482_RS18360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CG482_RS18375	COG4109	DRTGG domain
CG482_RS18380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG482_RS18385	COG0006	proline dipeptidase activity
CG482_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS18415	COG0589	response to stress
CG482_RS18440	COG0165	Argininosuccinate lyase
CG482_RS18445	COG0137	argininosuccinate synthase activity
CG482_RS18455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS18465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CG482_RS18470	COG0827	DNA restriction-modification system
CG482_RS18475	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CG482_RS18480	COG3874	Sporulation protein YtfJ
CG482_RS18495	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CG482_RS18500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG482_RS18510	COG0301	tRNA thio-modification
CG482_RS18515	COG1104	cysteine desulfurase activity
CG482_RS18520	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CG482_RS18530	COG0697	spore germination
CG482_RS18535	COG1309	transcriptional regulator
CG482_RS18540	COG1956	GAF domain-containing protein
CG482_RS18545	COG0626	cystathionine gamma-synthase activity
CG482_RS18555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG482_RS18585	COG1595	DNA-templated transcription, initiation
CG482_RS18600	COG0454	-acetyltransferase
CG482_RS18605	COG0517	IMP dehydrogenase activity
CG482_RS18610	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG482_RS18615	COG1970	mechanosensitive ion channel activity
CG482_RS18625	COG1609	Transcriptional regulator
CG482_RS18635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CG482_RS18635	COG1605	Chorismate mutase
CG482_RS18640	COG3118	belongs to the thioredoxin family
CG482_RS18650	COG2309	aminopeptidase activity
CG482_RS18665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG482_RS18685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG482_RS18690	COG4848	Belongs to the UPF0354 family
CG482_RS18695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_RS18700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CG482_RS18710	COG0675	Transposase, IS605 OrfB family
CG482_RS18720	COG1363	Peptidase, m42
CG482_RS18730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG482_RS18735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG482_RS18745	COG0510	thiamine kinase activity
CG482_RS18750	COG1523	belongs to the glycosyl hydrolase 13 family
CG482_RS18760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG482_RS18765	COG1349	DNA-binding transcription factor activity
CG482_RS18770	COG1187	pseudouridine synthase activity
CG482_RS18775	COG2244	polysaccharide biosynthetic process
CG482_RS18780	COG2081	HI0933 family
CG482_RS18785	COG2814	Major facilitator Superfamily
CG482_RS18795	COG3832	glyoxalase III activity
CG482_RS18815	COG0463	Glycosyl transferase, family 2
CG482_RS18870	COG1329	Transcriptional regulator
CG482_RS18880	COG2223	nitrite transmembrane transporter activity
CG482_RS18890	COG0314	molybdopterin synthase activity
CG482_RS18895	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG482_RS18900	COG0303	'Molybdopterin
CG482_RS18905	COG0315	cyclic pyranopterin monophosphate synthase activity
CG482_RS18910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CG482_RS18915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG482_RS18920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG482_RS18925	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CG482_RS18930	COG1140	nitrate reductase beta subunit
CG482_RS18935	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CG482_RS18940	COG2181	nitrate reductase activity
CG482_RS18955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG482_RS18965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CG482_RS19005	COG0495	leucyl-tRNA aminoacylation
CG482_RS19010	COG2814	Major facilitator Superfamily
CG482_RS19020	COG1136	(ABC) transporter
CG482_RS19025	COG0346	lactoylglutathione lyase activity
CG482_RS19040	COG1242	4 iron, 4 sulfur cluster binding
CG482_RS19045	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CG482_RS19050	COG1121	(ABC) transporter
CG482_RS19060	COG1794	racemase activity, acting on amino acids and derivatives
CG482_RS19070	COG2378	regulation of single-species biofilm formation
CG482_RS19095	COG0746	molybdenum cofactor guanylyltransferase activity
CG482_RS19120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG482_RS19130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG482_RS19175	COG3409	Peptidoglycan-binding domain 1 protein
CG482_RS19175	COG5632	N-Acetylmuramoyl-L-alanine amidase
CG482_RS19185	COG1368	sulfuric ester hydrolase activity
CG482_RS19200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG482_RS19205	COG1116	anion transmembrane transporter activity
CG482_RS19210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG482_RS19225	COG0494	nUDIX hydrolase
CG482_RS19235	COG1854	S-ribosylhomocysteine lyase activity
CG482_RS19240	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG482_RS19245	COG0288	reversible hydration of carbon dioxide
CG482_RS19250	COG1271	oxidase subunit
CG482_RS19255	COG1294	oxidase, subunit
CG482_RS19285	COG1842	Phage shock protein A
CG482_RS19325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CG482_RS19330	COG1597	lipid kinase activity
CG482_RS19335	COG0586	Pfam SNARE associated Golgi protein
CG482_RS19340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG482_RS19345	COG1136	(ABC) transporter
CG482_RS19355	COG0745	RESPONSE REGULATOR receiver
CG482_RS19360	COG2205	protein histidine kinase activity
CG482_RS19365	COG0577	efflux transmembrane transporter activity
CG482_RS19370	COG1136	(ABC) transporter
CG482_RS19390	COG4948	Mandelate Racemase Muconate Lactonizing
CG482_RS19395	COG0318	PFAM AMP-dependent synthetase and ligase
CG482_RS19400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG482_RS19405	COG0596	Alpha beta hydrolase
CG482_RS19410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CG482_RS19415	COG1169	isochorismate synthase
CG482_RS19420	COG1575	Belongs to the MenA family. Type 1 subfamily
CG482_RS19425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG482_RS19445	COG0058	SHG alpha-glucan phosphorylase activity
CG482_RS19450	COG0297	glycogen (starch) synthase activity
CG482_RS19455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG482_RS19460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG482_RS19465	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG482_RS19570	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG482_RS19605	COG1285	pathogenesis
CG482_RS19610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG482_RS19620	COG0166	Belongs to the GPI family
CG482_RS19630	COG2155	Conserved Protein
CG482_RS19635	COG1098	S1 RNA binding domain
CG482_RS19640	COG0436	Aminotransferase
CG482_RS19645	COG1522	sequence-specific DNA binding
CG482_RS19650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG482_RS19655	COG2267	carboxylic ester hydrolase activity
CG482_RS19665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CG482_RS19670	COG2032	superoxide dismutase activity
CG482_RS19680	COG5018	Exonuclease
CG482_RS19685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CG482_RS19705	COG2050	protein possibly involved in aromatic compounds catabolism
CG482_RS19715	COG1268	BioY protein
CG482_RS19720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG482_RS19725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG482_RS19735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG482_RS19745	COG3584	3D domain protein
CG482_RS19765	COG1252	NADH dehydrogenase
CG482_RS19770	COG0492	ferredoxin-NADP+ reductase activity
CG482_RS19785	COG1683	Conserved Protein
CG482_RS19795	COG0316	Belongs to the HesB IscA family
CG482_RS19800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG482_RS19805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_RS19815	COG1252	NADH dehydrogenase
CG482_RS19820	COG2824	Alkylphosphonate utilization operon protein PhnA
CG482_RS19830	COG3655	Transcriptional regulator
CG482_RS19845	COG4837	Protein of unknown function (DUF1462)
CG482_RS19850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG482_RS19855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG482_RS19860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CG482_RS19865	COG0647	UMP catabolic process
CG482_RS19875	COG2445	Protein of unknown function DUF86
CG482_RS19880	COG1494	fructose-1,6-bisphosphatase
CG482_RS19890	COG4470	Protein conserved in bacteria
CG482_RS19900	COG0789	Transcriptional regulator
CG482_RS19905	COG4377	Putative membrane peptidase family (DUF2324)
CG482_RS19920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG482_RS19925	COG0739	heme binding
CG482_RS19935	COG3377	Domain of unknown function (DUF1805)
CG482_RS19940	COG0737	Belongs to the 5'-nucleotidase family
CG482_RS19960	COG0719	Fe-S assembly protein
CG482_RS19965	COG0822	iron-sulfur transferase activity
CG482_RS19970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG482_RS19975	COG0719	Fe-S assembly protein
CG482_RS19980	COG0396	ATPase activity
CG482_RS19985	COG1464	Belongs to the NlpA lipoprotein family
CG482_RS19990	COG2011	ABC-type metal ion transport system permease component
CG482_RS20010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG482_RS20015	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CG482_RS20020	COG0509	glycine decarboxylation via glycine cleavage system
CG482_RS20025	COG1393	Belongs to the ArsC family
CG482_RS20070	COG1960	acyl-CoA dehydrogenase activity
CG482_RS20075	COG0183	Belongs to the thiolase family
CG482_RS20080	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG482_RS20080	COG1024	Enoyl-CoA hydratase
CG482_RS20090	COG1686	Belongs to the peptidase S11 family
CG482_RS20115	COG0011	TIGRFAM Protein of
CG482_RS20120	COG0840	transmembrane signaling receptor activity
CG482_RS20135	COG0531	amino acid
CG482_RS20140	COG0706	membrane insertase activity
CG482_RS20150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CG482_RS20160	COG5002	protein histidine kinase activity
CG482_RS20165	COG0745	RESPONSE REGULATOR receiver
CG482_RS20180	COG1131	(ABC) transporter
CG482_RS20190	COG0586	Pfam SNARE associated Golgi protein
CG482_RS20200	COG1376	ErfK ybiS ycfS ynhG family protein
CG482_RS20210	COG5002	protein histidine kinase activity
CG482_RS20215	COG0840	transmembrane signaling receptor activity
CG482_RS20220	COG0840	transmembrane signaling receptor activity
CG482_RS20225	COG2151	metal-sulfur cluster biosynthetic enzyme
CG482_RS20230	COG3227	Zinc metalloprotease (Elastase)
CG482_RS20235	COG1741	Belongs to the pirin family
CG482_RS20250	COG0783	Belongs to the Dps family
CG482_RS20255	COG1611	Belongs to the LOG family
CG482_RS20280	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG482_RS20285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG482_RS20290	COG1121	(ABC) transporter
CG482_RS20315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_RS20320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_RS20325	COG1115	amino acid carrier protein
CG482_RS20330	COG2910	NAD(P)H-binding
CG482_RS20345	COG1252	NADH dehydrogenase
CG482_RS20360	COG1595	DNA-templated transcription, initiation
CG482_RS20370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG482_RS20385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG482_RS20390	COG4977	sequence-specific DNA binding
CG482_RS20390	COG1917	Cupin 2, conserved barrel domain protein
CG482_RS20400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CG482_RS20420	COG0697	spore germination
CG482_RS20435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG482_RS20440	COG0557	exoribonuclease II activity
CG482_RS20445	COG1647	Serine aminopeptidase, S33
CG482_RS20450	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CG482_RS20455	COG1346	cytolysis
CG482_RS20465	COG0148	phosphopyruvate hydratase activity
CG482_RS20470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG482_RS20475	COG0149	triose-phosphate isomerase activity
CG482_RS20480	COG0126	phosphoglycerate kinase activity
CG482_RS20485	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CG482_RS20500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CG482_RS20525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG482_RS20540	COG2323	membrane
CG482_RS20555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_RS20560	COG1481	regulation of sporulation
CG482_RS20565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CG482_RS20570	COG1660	Displays ATPase and GTPase activities
CG482_RS20575	COG1051	belongs to the nudix hydrolase family
CG482_RS20585	COG0492	ferredoxin-NADP+ reductase activity
CG482_RS20590	COG0457	Tetratricopeptide repeat
CG482_RS20595	COG0110	maltose O-acetyltransferase activity
CG482_RS20605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG482_RS20610	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG482_RS20615	COG1950	PFAM Membrane protein of
CG482_RS20625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG482_RS20640	COG0789	Transcriptional regulator
CG482_RS20660	COG0583	DNA-binding transcription factor activity
CG482_RS20675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG482_RS20680	COG3409	Peptidoglycan-binding domain 1 protein
CG482_RS20680	COG0793	Belongs to the peptidase S41A family
CG482_RS20685	COG2177	Part of the ABC transporter FtsEX involved in
CG482_RS20690	COG2884	Cell division ATP-binding protein ftsE
CG482_RS20715	COG1278	Cold shock
CG482_RS20720	COG1040	competence protein
CG482_RS20725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CG482_RS20730	COG0791	NLP P60 protein
CG482_RS20730	COG1388	LysM domain
CG482_RS20735	COG1733	regulation of RNA biosynthetic process
CG482_RS20740	COG1307	EDD domain protein, DegV family
CG482_RS20745	COG1739	Uncharacterized protein family UPF0029
CG482_RS20750	COG1316	TRANSCRIPTIONal
CG482_RS20770	COG0457	Tetratricopeptide repeat
CG482_RS20800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CG482_RS20810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG482_RS20820	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CG482_RS20820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CG482_RS20835	COG1486	melibiose metabolic process
CG482_RS20840	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG482_RS20855	COG1447	Phosphotransferase system cellobiose-specific component IIA
CG482_RS20860	COG1301	dicarboxylic acid transport
CG482_RS20865	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CG482_RS20870	COG1271	oxidase subunit
CG482_RS20875	COG1294	oxidase, subunit
CG482_RS20880	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG482_RS20885	COG1620	l-lactate permease
CG482_RS20890	COG2389	metal-binding protein
CG482_RS20900	COG1368	sulfuric ester hydrolase activity
CG482_RS20915	COG1388	LysM domain
CG482_RS20915	COG0791	NLP P60 protein
CG482_RS20920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CG482_RS20930	COG1215	transferase activity, transferring glycosyl groups
CG482_RS20940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CG482_RS20945	COG1388	LysM domain
CG482_RS20945	COG3584	3D domain protein
CG482_RS20960	COG4715	Zinc finger, swim domain protein
CG482_RS20965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CG482_RS21005	COG0577	efflux transmembrane transporter activity
CG482_RS21010	COG1136	(ABC) transporter
CG482_RS21045	COG5002	protein histidine kinase activity
CG482_RS21045	COG3850	Histidine kinase
CG482_RS21050	COG0745	RESPONSE REGULATOR receiver
CG482_RS21055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG482_RS21065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG482_RS21070	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG482_RS21075	COG1134	teichoic acid transport
CG482_RS21080	COG1682	transport, permease protein
CG482_RS21085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG482_RS21095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG482_RS21100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CG482_RS21105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CG482_RS21115	COG1609	Transcriptional regulator
CG482_RS21125	COG0739	heme binding
CG482_RS21140	COG3279	Response regulator of the LytR AlgR family
CG482_RS21145	COG2385	sporulation resulting in formation of a cellular spore
CG482_RS21160	COG4836	Membrane
CG482_RS21165	COG1007	ATP synthesis coupled electron transport
CG482_RS21170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_RS21175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG482_RS21180	COG0713	ATP synthesis coupled electron transport
CG482_RS21185	COG0839	Belongs to the complex I subunit 6 family
CG482_RS21200	COG0649	NAD binding
CG482_RS21205	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_RS21210	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_RS21215	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG482_RS21220	COG5001	Diguanylate cyclase
CG482_RS21220	COG3300	MHYT domain
CG482_RS21225	COG3300	MHYT domain
CG482_RS21225	COG5001	Diguanylate cyclase
CG482_RS21240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG482_RS21245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG482_RS21250	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG482_RS21260	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG482_RS21265	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG482_RS21270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG482_RS21275	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG482_RS21300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG482_RS21305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG482_RS21315	COG0698	ribose 5-phosphate isomerase
CG482_RS21340	COG2259	Doxx family
CG482_RS21345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG482_RS21360	COG0009	L-threonylcarbamoyladenylate synthase
CG482_RS21375	COG2890	protein-(glutamine-N5) methyltransferase activity
CG482_RS21380	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG482_RS21385	COG1435	thymidine kinase activity
CG482_RS21395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG482_RS21400	COG1494	fructose-1,6-bisphosphatase
CG482_RS21420	COG4821	SIS domain
CG482_RS21425	COG0504	CTP synthase activity
CG482_RS21440	COG1960	acyl-CoA dehydrogenase activity
CG482_RS21445	COG1960	acyl-CoA dehydrogenase activity
CG482_RS21450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG482_RS21455	COG0183	Belongs to the thiolase family
CG482_RS21460	COG0247	lactate metabolic process
CG482_RS21460	COG2181	nitrate reductase activity
CG482_RS21465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG482_RS21485	COG2197	response regulator
CG482_RS21490	COG4585	Histidine kinase
CG482_RS21495	COG0842	Transport permease protein
CG482_RS21500	COG1131	(ABC) transporter
CG482_RS21510	COG2234	aminopeptidase activity
CG482_RS21525	COG4506	Protein conserved in bacteria
CG482_RS21530	COG1619	proteins homologs of microcin C7 resistance protein MccF
CG482_RS21550	COG0010	Belongs to the arginase family
CG482_RS21555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CG482_RS21560	COG2814	Major facilitator Superfamily
CG482_RS21565	COG0789	Transcriptional regulator
CG482_RS21570	COG0584	glycerophosphoryl diester phosphodiesterase
CG482_RS21575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG482_RS21580	COG2801	Transposase and inactivated derivatives
CG482_RS21585	COG1404	Belongs to the peptidase S8 family
CG482_RS21605	COG1994	Peptidase M50
CG482_RS21620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CG482_RS21625	COG1120	ATPase activity
CG482_RS21630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS21635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG482_RS21640	COG4844	belongs to the
CG482_RS21655	COG0280	phosphate acetyltransferase
CG482_RS21660	COG3253	May function as heme-dependent peroxidase
CG482_RS21670	COG3773	Cell wall hydrolase
CG482_RS21680	COG2363	Small membrane protein
CG482_RS21690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG482_RS21695	COG2233	PERMEase
CG482_RS21700	COG0561	phosphatase activity
CG482_RS21705	COG2814	Major facilitator Superfamily
CG482_RS21710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG482_RS21715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CG482_RS21720	COG1131	(ABC) transporter
CG482_RS21730	COG0460	homoserine dehydrogenase
CG482_RS21735	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CG482_RS21740	COG2873	o-acetylhomoserine
CG482_RS21750	COG0351	phosphomethylpyrimidine kinase
CG482_RS21760	COG1966	Carbon starvation protein
CG482_RS21765	COG3279	Response regulator of the LytR AlgR family
CG482_RS21775	COG0477	Major facilitator Superfamily
CG482_RS21785	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CG482_RS21790	COG0438	transferase activity, transferring glycosyl groups
CG482_RS21805	COG0840	transmembrane signaling receptor activity
CG482_RS21830	COG1607	acyl-coa hydrolase
CG482_RS21835	COG1216	Glycosyl transferase, family 2
CG482_RS21850	COG0463	Glycosyl transferase, family 2
CG482_RS21865	COG0463	Glycosyl transferase, family 2
CG482_RS21870	COG0488	(ABC) transporter
CG482_RS21875	COG1309	transcriptional regulator
CG482_RS21880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG482_RS21885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG482_RS21885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG482_RS21890	COG0628	permease
CG482_RS21895	COG1346	cytolysis
CG482_RS21905	COG3279	Response regulator of the LytR AlgR family
CG482_RS21910	COG3275	phosphorelay sensor kinase activity
CG482_RS21915	COG2814	Major facilitator Superfamily
CG482_RS21920	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CG482_RS21925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG482_RS21935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG482_RS21940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG482_RS21940	COG3711	transcriptional antiterminator
CG482_RS22030	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG482_RS22040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG482_RS22045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG482_RS22050	COG4853	Protein conserved in bacteria
CG482_RS22060	COG5002	protein histidine kinase activity
CG482_RS22065	COG0745	RESPONSE REGULATOR receiver
CG482_RS22090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG482_RS22095	COG0305	Participates in initiation and elongation during chromosome replication
CG482_RS22100	COG0359	binds to the 23S rRNA
CG482_RS22105	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CG482_RS22110	COG4241	membrane
CG482_RS22115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG482_RS22125	COG0360	Binds together with S18 to 16S ribosomal RNA
CG482_RS22130	COG0012	GTP binding
CG482_RS22135	COG4481	Protein conserved in bacteria
CG482_RS22140	COG0668	transmembrane transport
CG482_RS22150	COG1475	DNA binding
CG482_RS22155	COG1192	Involved in chromosome partitioning
CG482_RS22160	COG1475	DNA binding
CG482_RS22165	COG0357	Ribosomal RNA small subunit methyltransferase G
CG482_RS22170	COG0445	tRNA wobble uridine modification
CG482_RS22175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG482_RS22180	COG1847	R3H domain protein
CG482_RS22185	COG0706	membrane insertase activity
CG482_RS22190	COG0594	ribonuclease P activity
CG482_RS22195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CG482_RS22290	COG0457	Tetratricopeptide repeat
CG482_RS22325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG482_RS22330	COG3209	COG3209 Rhs family protein
CG482_RS22585	COG4974	Belongs to the 'phage' integrase family
CG482_RS22620	COG4166	transmembrane transport
CG482_RS22630	COG0457	Tetratricopeptide repeat
CG482_RS22670	COG1192	Involved in chromosome partitioning
CG482_RS22765	COG1028	Short-chain dehydrogenase reductase Sdr
CG482_RS22785	COG0583	DNA-binding transcription factor activity
CG482_RS22830	COG0741	lytic transglycosylase activity
CG482_RS22830	COG0791	NLP P60 protein