locus-tag	class	description
BCER98_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCER98_RS00010	COG0592	DNA-directed DNA polymerase activity
BCER98_RS00015	COG2501	S4 domain
BCER98_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCER98_RS00025	COG0187	DNA topoisomerase II activity
BCER98_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCER98_RS00065	COG0516	GMP reductase activity
BCER98_RS00065	COG0517	IMP dehydrogenase activity
BCER98_RS00070	COG1686	Belongs to the peptidase S11 family
BCER98_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BCER98_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BCER98_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCER98_RS00100	COG1428	Deoxynucleoside kinase
BCER98_RS00105	COG1428	Deoxynucleoside kinase
BCER98_RS00110	COG1335	isochorismatase
BCER98_RS00115	COG0590	tRNA wobble adenosine to inosine editing
BCER98_RS00120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCER98_RS00125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BCER98_RS00130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCER98_RS00175	COG1982	Orn Lys Arg decarboxylase major
BCER98_RS00180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BCER98_RS00185	COG0470	DNA polymerase III
BCER98_RS00190	COG1774	PSP1 C-terminal conserved region
BCER98_RS00195	COG4467	Involved in initiation control of chromosome replication
BCER98_RS00200	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCER98_RS00210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BCER98_RS00215	COG2002	toxin-antitoxin pair type II binding
BCER98_RS00225	COG0084	hydrolase, TatD family'
BCER98_RS00235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCER98_RS00245	COG4466	Protein conserved in bacteria
BCER98_RS00255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCER98_RS00260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCER98_RS00265	COG0251	oxidation-reduction process
BCER98_RS00270	COG2088	sporulation resulting in formation of a cellular spore
BCER98_RS00275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCER98_RS00285	COG0193	aminoacyl-tRNA hydrolase activity
BCER98_RS00295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BCER98_RS00300	COG2002	toxin-antitoxin pair type II binding
BCER98_RS00305	COG2244	polysaccharide biosynthetic process
BCER98_RS00310	COG3956	TIGRFAM MazG family protein
BCER98_RS00315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BCER98_RS00335	COG1098	S1 RNA binding domain
BCER98_RS00350	COG2208	phosphoserine phosphatase activity
BCER98_RS00360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCER98_RS00365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCER98_RS00370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BCER98_RS00375	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BCER98_RS00380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCER98_RS00385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCER98_RS00390	COG0512	Glutamine amidotransferase of anthranilate synthase
BCER98_RS00395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCER98_RS00400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCER98_RS00405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCER98_RS00410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCER98_RS00415	COG1396	sequence-specific DNA binding
BCER98_RS00420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCER98_RS00425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCER98_RS00460	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCER98_RS00510	COG3880	PFAM UvrB UvrC protein
BCER98_RS00515	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BCER98_RS00520	COG0542	response to heat
BCER98_RS00525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCER98_RS00535	COG4956	integral membrane protein (PIN domain superfamily)
BCER98_RS00540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCER98_RS00545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCER98_RS00550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCER98_RS00555	COG1045	serine acetyltransferase
BCER98_RS00560	COG0215	cysteine-tRNA ligase activity
BCER98_RS00570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCER98_RS00575	COG3688	RNA-binding protein containing a PIN domain
BCER98_RS00590	COG0250	Participates in transcription elongation, termination and antitermination
BCER98_RS00595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCER98_RS00600	COG0081	regulation of translation
BCER98_RS00605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCER98_RS00610	COG0222	ribosome binding
BCER98_RS00615	COG2813	Specifically methylates the guanine in position
BCER98_RS00625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCER98_RS00630	COG1358	cellular component organization or biogenesis
BCER98_RS00635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCER98_RS00640	COG0049	tRNA binding
BCER98_RS00645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCER98_RS00650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCER98_RS00660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCER98_RS00665	COG0088	Forms part of the polypeptide exit tunnel
BCER98_RS00670	COG0089	rRNA binding
BCER98_RS00675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCER98_RS00680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCER98_RS00685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCER98_RS00690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCER98_RS00695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCER98_RS00700	COG0255	Belongs to the universal ribosomal protein uL29 family
BCER98_RS00705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCER98_RS00710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCER98_RS00715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCER98_RS00720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCER98_RS00730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCER98_RS00740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BCER98_RS00745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCER98_RS00750	COG1841	ribosomal large subunit assembly
BCER98_RS00755	COG0200	Binds to the 23S rRNA
BCER98_RS00760	COG0201	protein transport
BCER98_RS00765	COG0563	adenylate kinase activity
BCER98_RS00770	COG0024	Methionine aminopeptidase
BCER98_RS00780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BCER98_RS00785	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCER98_RS00790	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCER98_RS00795	COG0202	RNA polymerase activity
BCER98_RS00815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BCER98_RS00825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCER98_RS00830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCER98_RS00840	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCER98_RS00845	COG0489	protein tyrosine kinase activity
BCER98_RS00855	COG2194	sulfuric ester hydrolase activity
BCER98_RS00860	COG0726	polysaccharide deacetylase
BCER98_RS00940	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BCER98_RS00950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCER98_RS00965	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCER98_RS00975	COG0489	protein tyrosine kinase activity
BCER98_RS00980	COG0019	diaminopimelate decarboxylase activity
BCER98_RS01000	COG1266	CAAX protease self-immunity
BCER98_RS01075	COG3681	Belongs to the UPF0597 family
BCER98_RS01095	COG2814	Major facilitator Superfamily
BCER98_RS01105	COG0601	transmembrane transport
BCER98_RS01110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCER98_RS01115	COG0444	Belongs to the ABC transporter superfamily
BCER98_RS01120	COG4608	Belongs to the ABC transporter superfamily
BCER98_RS01125	COG4166	transmembrane transport
BCER98_RS01145	COG1309	transcriptional regulator
BCER98_RS01155	COG0656	L-ascorbic acid biosynthetic process
BCER98_RS01160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCER98_RS01170	COG4149	molybdate abc transporter
BCER98_RS01175	COG0725	ABC transporter, periplasmic molybdate-binding protein
BCER98_RS01180	COG1910	domain protein
BCER98_RS01185	COG0204	Acyl-transferase
BCER98_RS01190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS01195	COG1648	precorrin-2 dehydrogenase activity
BCER98_RS01195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCER98_RS01205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCER98_RS01205	COG1587	Uroporphyrinogen-III synthase
BCER98_RS01210	COG2146	nitrite reductase [NAD(P)H] activity
BCER98_RS01215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCER98_RS01240	COG4585	Histidine kinase
BCER98_RS01245	COG2197	response regulator
BCER98_RS01250	COG1131	(ABC) transporter
BCER98_RS01255	COG0842	Transport permease protein
BCER98_RS01255	COG1511	domain protein
BCER98_RS01260	COG0842	Transport permease protein
BCER98_RS01270	COG0747	negative chemotaxis
BCER98_RS01275	COG0601	transmembrane transport
BCER98_RS01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCER98_RS01285	COG0444	Belongs to the ABC transporter superfamily
BCER98_RS01290	COG4608	Belongs to the ABC transporter superfamily
BCER98_RS01295	COG0561	phosphatase activity
BCER98_RS01315	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BCER98_RS01320	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCER98_RS01330	COG2814	Major facilitator Superfamily
BCER98_RS01335	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCER98_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCER98_RS01350	COG0705	Rhomboid family
BCER98_RS01350	COG0457	Tetratricopeptide repeat
BCER98_RS01355	COG0736	holo-[acyl-carrier-protein] synthase activity
BCER98_RS01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCER98_RS01370	COG0864	Transcriptional regulator
BCER98_RS01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
BCER98_RS01380	COG2183	response to ionizing radiation
BCER98_RS01385	COG3091	SprT-like family
BCER98_RS01425	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCER98_RS01475	COG0802	atpase or kinase
BCER98_RS01480	COG1214	PFAM Peptidase M22, glycoprotease
BCER98_RS01485	COG0456	acetyltransferase
BCER98_RS01495	COG0488	(ABC) transporter
BCER98_RS01500	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BCER98_RS01510	COG1266	CAAX protease self-immunity
BCER98_RS01515	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCER98_RS01520	COG0459	protein refolding
BCER98_RS01525	COG0519	Catalyzes the synthesis of GMP from XMP
BCER98_RS01525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCER98_RS01530	COG2252	PERMEase
BCER98_RS01540	COG5002	protein histidine kinase activity
BCER98_RS01605	COG2205	protein histidine kinase activity
BCER98_RS01610	COG0745	RESPONSE REGULATOR receiver
BCER98_RS01630	COG0697	spore germination
BCER98_RS01650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCER98_RS01655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCER98_RS01660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCER98_RS01665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BCER98_RS01670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCER98_RS01675	COG0047	phosphoribosylformylglycinamidine synthase activity
BCER98_RS01680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCER98_RS01685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCER98_RS01690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCER98_RS01695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCER98_RS01700	COG0138	bifunctional purine biosynthesis protein purh
BCER98_RS01705	COG0151	Belongs to the GarS family
BCER98_RS01715	COG0583	DNA-binding transcription factor activity
BCER98_RS01735	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BCER98_RS01740	COG0210	DNA helicase
BCER98_RS01745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCER98_RS01750	COG4851	CamS sex pheromone cAM373 precursor
BCER98_RS01760	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS01765	COG1335	isochorismatase
BCER98_RS01775	COG2011	ABC-type metal ion transport system permease component
BCER98_RS01795	COG4682	membrane
BCER98_RS01800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCER98_RS01805	COG0154	amidase activity
BCER98_RS01810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCER98_RS01815	COG1597	lipid kinase activity
BCER98_RS01820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCER98_RS01825	COG0546	phosphoglycolate phosphatase activity
BCER98_RS01830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCER98_RS01840	COG0531	amino acid
BCER98_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS01850	COG2076	Multidrug Resistance protein
BCER98_RS01855	COG2309	aminopeptidase activity
BCER98_RS01865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCER98_RS01870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCER98_RS01875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BCER98_RS01890	COG0450	alkyl hydroperoxide reductase
BCER98_RS01915	COG0714	Associated with various cellular activities
BCER98_RS01955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS01960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS01965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCER98_RS01970	COG0492	ferredoxin-NADP+ reductase activity
BCER98_RS01980	COG0166	Belongs to the GPI family
BCER98_RS02010	COG3541	Predicted nucleotidyltransferase
BCER98_RS02015	COG2814	Major facilitator Superfamily
BCER98_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCER98_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
BCER98_RS02030	COG0765	amino acid transport
BCER98_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCER98_RS02045	COG0840	transmembrane signaling receptor activity
BCER98_RS02055	COG2235	arginine
BCER98_RS02070	COG0549	Belongs to the carbamate kinase family
BCER98_RS02075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCER98_RS02085	COG0366	Alpha amylase catalytic
BCER98_RS02090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCER98_RS02090	COG2190	(PTS) system
BCER98_RS02090	COG1263	PTS System
BCER98_RS02115	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS02120	COG4605	iron ion homeostasis
BCER98_RS02125	COG4604	ABC transporter, ATP-binding protein
BCER98_RS02130	COG4607	ABC-type enterochelin transport system periplasmic component
BCER98_RS02135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BCER98_RS02140	COG0352	thiamine-phosphate diphosphorylase activity
BCER98_RS02145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BCER98_RS02165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCER98_RS02175	COG1116	anion transmembrane transporter activity
BCER98_RS02210	COG2270	Major facilitator Superfamily
BCER98_RS02235	COG2310	stress, protein
BCER98_RS02240	COG2310	stress, protein
BCER98_RS02245	COG2310	stress, protein
BCER98_RS02250	COG0861	Integral membrane protein TerC family
BCER98_RS02260	COG3853	Toxic anion resistance protein (TelA)
BCER98_RS02270	COG4840	Belongs to the UPF0435 family
BCER98_RS02275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCER98_RS02285	COG1295	ribonuclease BN
BCER98_RS02290	COG2217	Heavy metal translocating P-type atpase
BCER98_RS02295	COG0697	spore germination
BCER98_RS02305	COG0681	Belongs to the peptidase S26 family
BCER98_RS02315	COG0586	Pfam SNARE associated Golgi protein
BCER98_RS02330	COG0387	Pfam Sodium calcium exchanger
BCER98_RS02340	COG0535	radical SAM domain protein
BCER98_RS02360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BCER98_RS02385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCER98_RS02430	COG2066	Belongs to the glutaminase family
BCER98_RS02435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCER98_RS02435	COG1263	PTS System
BCER98_RS02440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCER98_RS02450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCER98_RS02450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCER98_RS02460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BCER98_RS02465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCER98_RS02475	COG0402	S-adenosylhomocysteine deaminase activity
BCER98_RS02480	COG2137	regulation of response to DNA damage stimulus
BCER98_RS02500	COG1988	membrane-bound metal-dependent
BCER98_RS02505	COG1194	a g-specific adenine glycosylase
BCER98_RS02510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BCER98_RS02530	COG3557	Belongs to the UPF0374 family
BCER98_RS02535	COG1132	(ABC) transporter
BCER98_RS02540	COG4129	membrane
BCER98_RS02545	COG0069	glutamate synthase activity
BCER98_RS02545	COG0067	glutamate synthase
BCER98_RS02545	COG0070	glutamate synthase
BCER98_RS02550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCER98_RS02555	COG4555	ABC transporter
BCER98_RS02575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BCER98_RS02580	COG0735	belongs to the Fur family
BCER98_RS02700	COG0457	Tetratricopeptide repeat
BCER98_RS02705	COG0217	transcriptional regulatory protein
BCER98_RS02710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCER98_RS02715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCER98_RS02735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCER98_RS02740	COG2766	serine protein kinase
BCER98_RS02745	COG2718	Belongs to the UPF0229 family
BCER98_RS02760	COG1280	lysine exporter protein (LysE YggA)
BCER98_RS02795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCER98_RS02805	COG1585	Membrane protein implicated in regulation of membrane protease activity
BCER98_RS02810	COG2268	Band 7 protein
BCER98_RS02840	COG4990	cell redox homeostasis
BCER98_RS02850	COG3290	protein histidine kinase activity
BCER98_RS02855	COG4565	transcriptional regulatory protein
BCER98_RS02860	COG3493	citrate carrier protein
BCER98_RS02865	COG0281	malic enzyme
BCER98_RS02880	COG5002	protein histidine kinase activity
BCER98_RS02885	COG0745	RESPONSE REGULATOR receiver
BCER98_RS02895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BCER98_RS02900	COG3383	formate dehydrogenase (NAD+) activity
BCER98_RS02905	COG2427	Protein of unknown function (DUF1641)
BCER98_RS02915	COG0840	transmembrane signaling receptor activity
BCER98_RS02925	COG0531	amino acid
BCER98_RS02930	COG0640	Transcriptional regulator
BCER98_RS02935	COG2217	Heavy metal translocating P-type atpase
BCER98_RS02940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BCER98_RS02950	COG3227	Zinc metalloprotease (Elastase)
BCER98_RS02965	COG2217	Heavy metal translocating P-type atpase
BCER98_RS02985	COG2720	vancomycin resistance protein
BCER98_RS02990	COG1316	TRANSCRIPTIONal
BCER98_RS02995	COG1253	flavin adenine dinucleotide binding
BCER98_RS03000	COG1027	Aspartate ammonia-lyase
BCER98_RS03005	COG1620	l-lactate permease
BCER98_RS03020	COG3104	oligopeptide transport
BCER98_RS03025	COG0156	8-amino-7-oxononanoate synthase activity
BCER98_RS03030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCER98_RS03035	COG4548	von Willebrand factor, type A
BCER98_RS03040	COG0714	Associated with various cellular activities
BCER98_RS03045	COG0531	amino acid
BCER98_RS03055	COG1115	amino acid carrier protein
BCER98_RS03060	COG1126	abc transporter atp-binding protein
BCER98_RS03065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCER98_RS03070	COG0765	amino acid transport
BCER98_RS03075	COG0765	amino acid transport
BCER98_RS03080	COG0833	amino acid
BCER98_RS03090	COG5002	protein histidine kinase activity
BCER98_RS03095	COG0745	RESPONSE REGULATOR receiver
BCER98_RS03105	COG0659	secondary active sulfate transmembrane transporter activity
BCER98_RS03110	COG0589	response to stress
BCER98_RS03115	COG0747	negative chemotaxis
BCER98_RS03125	COG0601	transmembrane transport
BCER98_RS03130	COG4608	Belongs to the ABC transporter superfamily
BCER98_RS03140	COG2271	Major facilitator Superfamily
BCER98_RS03145	COG1846	Transcriptional regulator
BCER98_RS03150	COG0477	Major facilitator Superfamily
BCER98_RS03155	COG1609	Transcriptional regulator
BCER98_RS03160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCER98_RS03165	COG1869	D-ribose catabolic process
BCER98_RS03175	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCER98_RS03180	COG1879	ABC-type sugar transport system periplasmic component
BCER98_RS03185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCER98_RS03200	COG3568	Endonuclease Exonuclease Phosphatase
BCER98_RS03225	COG0840	transmembrane signaling receptor activity
BCER98_RS03230	COG1388	LysM domain
BCER98_RS03230	COG3584	3D domain protein
BCER98_RS03235	COG1476	TRANSCRIPTIONal
BCER98_RS03265	COG1114	Component of the transport system for branched-chain amino acids
BCER98_RS03275	COG1113	amino acid transport
BCER98_RS03280	COG2153	protein acetylation
BCER98_RS03290	COG0569	domain protein
BCER98_RS03290	COG0475	glutathione-regulated potassium exporter activity
BCER98_RS03305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCER98_RS03310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCER98_RS03315	COG0833	amino acid
BCER98_RS03320	COG4990	cell redox homeostasis
BCER98_RS03335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS03340	COG0697	spore germination
BCER98_RS03345	COG0531	amino acid
BCER98_RS03355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCER98_RS03360	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCER98_RS03365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BCER98_RS03365	COG1918	ferrous iron import across plasma membrane
BCER98_RS03370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCER98_RS03375	COG0573	inorganic phosphate transmembrane transporter activity
BCER98_RS03380	COG0581	inorganic phosphate transmembrane transporter activity
BCER98_RS03385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCER98_RS03425	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCER98_RS03505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BCER98_RS03530	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCER98_RS03535	COG1116	anion transmembrane transporter activity
BCER98_RS03540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCER98_RS03545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCER98_RS03550	COG0352	thiamine-phosphate diphosphorylase activity
BCER98_RS03555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCER98_RS03560	COG2104	thiamine diphosphate biosynthetic process
BCER98_RS03565	COG2022	thiamine diphosphate biosynthetic process
BCER98_RS03570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCER98_RS03575	COG0351	phosphomethylpyrimidine kinase
BCER98_RS03600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BCER98_RS03605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BCER98_RS03610	COG2205	protein histidine kinase activity
BCER98_RS03615	COG2814	Major facilitator Superfamily
BCER98_RS03620	COG1846	Transcriptional regulator
BCER98_RS03630	COG2252	PERMEase
BCER98_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS03640	COG1376	ErfK ybiS ycfS ynhG family protein
BCER98_RS03695	COG0778	Nitroreductase
BCER98_RS03705	COG2719	SpoVR family
BCER98_RS03715	COG1316	TRANSCRIPTIONal
BCER98_RS03720	COG1283	sodium-dependent phosphate transmembrane transporter activity
BCER98_RS03735	COG0577	efflux transmembrane transporter activity
BCER98_RS03740	COG1136	(ABC) transporter
BCER98_RS03750	COG1114	Component of the transport system for branched-chain amino acids
BCER98_RS03755	COG3546	catalase activity
BCER98_RS03805	COG0475	glutathione-regulated potassium exporter activity
BCER98_RS03810	COG1737	Transcriptional regulator
BCER98_RS03820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCER98_RS03825	COG1263	PTS System
BCER98_RS03825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCER98_RS03870	COG1522	sequence-specific DNA binding
BCER98_RS03885	COG0531	amino acid
BCER98_RS03895	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS03900	COG1132	(ABC) transporter
BCER98_RS03905	COG1132	(ABC) transporter
BCER98_RS03910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCER98_RS03915	COG0765	amino acid transport
BCER98_RS03920	COG1126	abc transporter atp-binding protein
BCER98_RS03935	COG0189	ligase activity
BCER98_RS03940	COG4399	Belongs to the UPF0754 family
BCER98_RS03945	COG3679	Belongs to the UPF0342 family
BCER98_RS03950	COG4585	Histidine kinase
BCER98_RS03955	COG2197	response regulator
BCER98_RS03990	COG2094	Belongs to the DNA glycosylase MPG family
BCER98_RS03995	COG0561	phosphatase activity
BCER98_RS04005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCER98_RS04035	COG2244	polysaccharide biosynthetic process
BCER98_RS04045	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCER98_RS04065	COG1696	Membrane protein involved in D-alanine export
BCER98_RS04080	COG1024	Enoyl-CoA hydratase
BCER98_RS04090	COG1363	Peptidase, m42
BCER98_RS04105	COG2239	Acts as a magnesium transporter
BCER98_RS04110	COG0772	Belongs to the SEDS family
BCER98_RS04115	COG1115	amino acid carrier protein
BCER98_RS04205	COG0457	Tetratricopeptide repeat
BCER98_RS04210	COG0477	Major facilitator Superfamily
BCER98_RS04270	COG1061	Type III restriction enzyme res subunit
BCER98_RS04285	COG3829	transcription factor binding
BCER98_RS04290	COG4638	Rieske (2fe-2S)
BCER98_RS04295	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS04300	COG0473	3-isopropylmalate dehydrogenase activity
BCER98_RS04310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS04315	COG1064	alcohol dehydrogenase
BCER98_RS04330	COG3246	L-lysine catabolic process to acetate
BCER98_RS04340	COG0305	Participates in initiation and elongation during chromosome replication
BCER98_RS04370	COG4641	Protein conserved in bacteria
BCER98_RS04380	COG3711	transcriptional antiterminator
BCER98_RS04385	COG1263	PTS System
BCER98_RS04385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCER98_RS04385	COG2190	(PTS) system
BCER98_RS04390	COG2723	6-phospho-beta-galactosidase activity
BCER98_RS04430	COG0420	3'-5' exonuclease activity
BCER98_RS04435	COG4717	serine-type aminopeptidase activity
BCER98_RS04440	COG3481	metal-dependent phosphohydrolase, HD sub domain
BCER98_RS04450	COG0577	efflux transmembrane transporter activity
BCER98_RS04455	COG1136	(ABC) transporter
BCER98_RS04460	COG5002	protein histidine kinase activity
BCER98_RS04465	COG0745	RESPONSE REGULATOR receiver
BCER98_RS04470	COG1316	TRANSCRIPTIONal
BCER98_RS04485	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BCER98_RS04490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCER98_RS04495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCER98_RS04500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCER98_RS04520	COG1846	Transcriptional regulator
BCER98_RS04525	COG4980	gas vesicle protein
BCER98_RS04535	COG0537	adenosine 5'-monophosphoramidase activity
BCER98_RS04540	COG1131	(ABC) transporter
BCER98_RS04545	COG4473	ABC transporter
BCER98_RS04555	COG3402	PFAM membrane-flanked domain
BCER98_RS04565	COG2329	Antibiotic biosynthesis monooxygenase
BCER98_RS04570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCER98_RS04575	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCER98_RS04580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCER98_RS04585	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCER98_RS04615	COG1309	transcriptional regulator
BCER98_RS04625	COG0438	transferase activity, transferring glycosyl groups
BCER98_RS04625	COG1216	Glycosyl transferase, family 2
BCER98_RS04635	COG1609	Transcriptional regulator
BCER98_RS04640	COG1234	tRNA 3'-trailer cleavage
BCER98_RS04645	COG0095	Lipoate-protein ligase
BCER98_RS04655	COG0318	PFAM AMP-dependent synthetase and ligase
BCER98_RS04670	COG2205	protein histidine kinase activity
BCER98_RS04675	COG0745	RESPONSE REGULATOR receiver
BCER98_RS04695	COG0501	Belongs to the peptidase M48B family
BCER98_RS04700	COG0840	transmembrane signaling receptor activity
BCER98_RS04705	COG0697	spore germination
BCER98_RS04720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BCER98_RS04725	COG2224	Isocitrate lyase
BCER98_RS04730	COG1278	Cold shock
BCER98_RS04735	COG4903	ComK protein
BCER98_RS04740	COG0398	Pfam SNARE associated Golgi protein
BCER98_RS04750	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BCER98_RS04755	COG1074	ATP-dependent DNA helicase activity
BCER98_RS04795	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCER98_RS04815	COG0367	asparagine synthase
BCER98_RS04825	COG0753	catalase activity
BCER98_RS04835	COG0366	Alpha amylase catalytic
BCER98_RS04835	COG1874	Beta-galactosidase
BCER98_RS04840	COG1666	GTP binding
BCER98_RS04845	COG2996	Protein conserved in bacteria
BCER98_RS04855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS04870	COG0561	phosphatase activity
BCER98_RS04890	COG2267	carboxylic ester hydrolase activity
BCER98_RS04905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCER98_RS04910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCER98_RS04915	COG5504	Zn-dependent protease
BCER98_RS04925	COG0180	Tryptophanyl-tRNA synthetase
BCER98_RS04940	COG0601	transmembrane transport
BCER98_RS04945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCER98_RS04950	COG0444	Belongs to the ABC transporter superfamily
BCER98_RS04955	COG4608	Belongs to the ABC transporter superfamily
BCER98_RS04960	COG0534	Mate efflux family protein
BCER98_RS04965	COG4166	transmembrane transport
BCER98_RS04980	COG0861	Integral membrane protein TerC family
BCER98_RS05000	COG1164	Oligoendopeptidase f
BCER98_RS05010	COG2346	COG2346, Truncated hemoglobins
BCER98_RS05015	COG4116	CYTH
BCER98_RS05025	COG2357	RelA SpoT domain protein
BCER98_RS05035	COG0564	pseudouridine synthase activity
BCER98_RS05045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCER98_RS05050	COG0772	Belongs to the SEDS family
BCER98_RS05095	COG1216	Glycosyl transferase, family 2
BCER98_RS05115	COG0457	Tetratricopeptide repeat
BCER98_RS05115	COG0463	Glycosyl transferase, family 2
BCER98_RS05135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCER98_RS05150	COG1091	dTDP-4-dehydrorhamnose reductase activity
BCER98_RS05175	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCER98_RS05180	COG2382	esterase
BCER98_RS05190	COG5492	domain, Protein
BCER98_RS05195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS05205	COG1620	l-lactate permease
BCER98_RS05210	COG5634	Uncharacterized conserved protein (DUF2278)
BCER98_RS05250	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCER98_RS05255	COG0567	Dehydrogenase, E1 component
BCER98_RS05265	COG0583	DNA-binding transcription factor activity
BCER98_RS05270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCER98_RS05275	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS05290	COG0196	riboflavin kinase activity
BCER98_RS05295	COG3162	membrane
BCER98_RS05300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS05305	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCER98_RS05320	COG0457	Tetratricopeptide repeat
BCER98_RS05405	COG0457	Tetratricopeptide repeat
BCER98_RS05410	COG0582	viral genome integration into host DNA
BCER98_RS05440	COG1686	Belongs to the peptidase S11 family
BCER98_RS05445	COG0681	Belongs to the peptidase S26 family
BCER98_RS05480	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS05490	COG1176	ABC-type spermidine putrescine transport system, permease component I
BCER98_RS05495	COG1177	transmembrane transport
BCER98_RS05500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BCER98_RS05505	COG0671	phosphoesterase, PA-phosphatase related
BCER98_RS05510	COG2409	Drug exporters of the RND superfamily
BCER98_RS05520	COG0564	pseudouridine synthase activity
BCER98_RS05530	COG2340	Cysteine-rich secretory protein family
BCER98_RS05535	COG0247	lactate metabolic process
BCER98_RS05540	COG0277	FAD linked oxidase domain protein
BCER98_RS05545	COG3835	regulator
BCER98_RS05555	COG0745	RESPONSE REGULATOR receiver
BCER98_RS05560	COG5002	protein histidine kinase activity
BCER98_RS05565	COG2186	Transcriptional regulator
BCER98_RS05570	COG0247	lactate metabolic process
BCER98_RS05575	COG1139	Iron-sulfur cluster binding protein
BCER98_RS05580	COG1556	Lactate utilization protein
BCER98_RS05585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BCER98_RS05590	COG0584	glycerophosphoryl diester phosphodiesterase
BCER98_RS05600	COG2267	carboxylic ester hydrolase activity
BCER98_RS05605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCER98_RS05625	COG2116	formate transmembrane transporter activity
BCER98_RS05630	COG0861	Integral membrane protein TerC family
BCER98_RS05635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCER98_RS05645	COG2030	dehydratase
BCER98_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS05670	COG3243	poly(R)-hydroxyalkanoic acid synthase
BCER98_RS05675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCER98_RS05690	COG1840	ABC-type Fe3 transport system, periplasmic component
BCER98_RS05695	COG3842	ATPase activity
BCER98_RS05705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCER98_RS05710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BCER98_RS05715	COG1349	DNA-binding transcription factor activity
BCER98_RS05720	COG0235	Class ii aldolase
BCER98_RS05730	COG2861	carbohydrate metabolic process
BCER98_RS05745	COG3852	Histidine kinase
BCER98_RS05750	COG1846	Transcriptional regulator
BCER98_RS05770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BCER98_RS05775	COG0720	synthase
BCER98_RS05785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BCER98_RS05790	COG4873	Protein conserved in bacteria
BCER98_RS05800	COG0456	acetyltransferase
BCER98_RS05815	COG1780	Probably involved in ribonucleotide reductase function
BCER98_RS05820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCER98_RS05825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCER98_RS05830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCER98_RS05835	COG1725	Transcriptional regulator
BCER98_RS05840	COG1131	(ABC) transporter
BCER98_RS05850	COG1131	(ABC) transporter
BCER98_RS05855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCER98_RS05870	COG1522	sequence-specific DNA binding
BCER98_RS05885	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCER98_RS05890	COG2070	2-Nitropropane dioxygenase
BCER98_RS05895	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BCER98_RS05905	COG1696	Membrane protein involved in D-alanine export
BCER98_RS05910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCER98_RS05925	COG0716	FMN binding
BCER98_RS05950	COG1368	sulfuric ester hydrolase activity
BCER98_RS05975	COG5609	conserved protein (DUF2294)
BCER98_RS05980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCER98_RS05985	COG3002	Belongs to the UPF0753 family
BCER98_RS05990	COG0288	reversible hydration of carbon dioxide
BCER98_RS05995	COG0534	Mate efflux family protein
BCER98_RS06010	COG1846	Transcriptional regulator
BCER98_RS06020	COG1301	dicarboxylic acid transport
BCER98_RS06025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCER98_RS06035	COG3874	Sporulation protein YtfJ
BCER98_RS06055	COG0028	Belongs to the TPP enzyme family
BCER98_RS06060	COG0440	acetolactate synthase activity
BCER98_RS06065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCER98_RS06070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCER98_RS06080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCER98_RS06085	COG0066	3-isopropylmalate dehydratase activity
BCER98_RS06095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCER98_RS06105	COG0131	Imidazoleglycerol-phosphate dehydratase
BCER98_RS06110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCER98_RS06115	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCER98_RS06120	COG0107	imidazoleglycerol-phosphate synthase activity
BCER98_RS06125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCER98_RS06130	COG0140	phosphoribosyl-ATP diphosphatase activity
BCER98_RS06140	COG1183	phosphatidylcholine synthase activity
BCER98_RS06145	COG1368	sulfuric ester hydrolase activity
BCER98_RS06155	COG0019	diaminopimelate decarboxylase activity
BCER98_RS06160	COG0175	sulfate reduction
BCER98_RS06165	COG2046	Belongs to the sulfate adenylyltransferase family
BCER98_RS06170	COG0529	Catalyzes the synthesis of activated sulfate
BCER98_RS06175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCER98_RS06195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCER98_RS06195	COG1648	precorrin-2 dehydrogenase activity
BCER98_RS06200	COG0733	neurotransmitter:sodium symporter activity
BCER98_RS06215	COG3557	Belongs to the UPF0374 family
BCER98_RS06220	COG1757	Na H antiporter
BCER98_RS06235	COG4758	membrane
BCER98_RS06240	COG4585	Histidine kinase
BCER98_RS06245	COG2197	response regulator
BCER98_RS06250	COG1114	Component of the transport system for branched-chain amino acids
BCER98_RS06255	COG1525	nuclease
BCER98_RS06255	COG0737	Belongs to the 5'-nucleotidase family
BCER98_RS06255	COG4085	toxin activity
BCER98_RS06285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCER98_RS06285	COG3711	transcriptional antiterminator
BCER98_RS06290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCER98_RS06290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCER98_RS06290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCER98_RS06295	COG1482	cell wall glycoprotein biosynthetic process
BCER98_RS06320	COG0730	response to heat
BCER98_RS06325	COG0306	phosphate transporter
BCER98_RS06330	COG1392	Phosphate transport regulator
BCER98_RS06335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCER98_RS06345	COG3852	Histidine kinase
BCER98_RS06350	COG1801	Protein of unknown function DUF72
BCER98_RS06360	COG0582	viral genome integration into host DNA
BCER98_RS06365	COG5002	protein histidine kinase activity
BCER98_RS06370	COG0813	purine-nucleoside phosphorylase activity
BCER98_RS06380	COG0392	lysyltransferase activity
BCER98_RS06380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BCER98_RS06395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCER98_RS06400	COG1686	Belongs to the peptidase S11 family
BCER98_RS06405	COG2715	membrane protein required for spore maturation
BCER98_RS06410	COG0700	Nucleoside recognition
BCER98_RS06415	COG1187	pseudouridine synthase activity
BCER98_RS06425	COG1333	cytochrome c biogenesis protein
BCER98_RS06430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCER98_RS06435	COG0745	RESPONSE REGULATOR receiver
BCER98_RS06440	COG5002	protein histidine kinase activity
BCER98_RS06445	COG2096	Adenosyltransferase
BCER98_RS06460	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BCER98_RS06465	COG1141	Ferredoxin
BCER98_RS06475	COG0514	ATP-dependent DNA helicase (RecQ)
BCER98_RS06480	COG1266	CAAX protease self-immunity
BCER98_RS06490	COG1408	metallophosphoesterase
BCER98_RS06505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCER98_RS06520	COG0492	ferredoxin-NADP+ reductase activity
BCER98_RS06525	COG0252	asparaginase activity
BCER98_RS06530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCER98_RS06540	COG1304	FMN binding
BCER98_RS06560	COG1160	GTP binding
BCER98_RS06565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCER98_RS06585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCER98_RS06595	COG0302	gtp cyclohydrolase
BCER98_RS06600	COG0142	geranyltranstransferase activity
BCER98_RS06605	COG2226	methyltransferase
BCER98_RS06610	COG0142	geranyltranstransferase activity
BCER98_RS06620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCER98_RS06625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCER98_RS06630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCER98_RS06635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BCER98_RS06640	COG0457	Tetratricopeptide repeat
BCER98_RS06645	COG5582	Belongs to the UPF0302 family
BCER98_RS06660	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCER98_RS06670	COG4347	Protein of unknown function (DUF1405)
BCER98_RS06685	COG2738	Putative neutral zinc metallopeptidase
BCER98_RS06695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS06700	COG1694	Mazg nucleotide pyrophosphohydrolase
BCER98_RS06705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCER98_RS06710	COG1803	Methylglyoxal synthase
BCER98_RS06715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCER98_RS06720	COG0438	transferase activity, transferring glycosyl groups
BCER98_RS06725	COG0617	tRNA 3'-terminal CCA addition
BCER98_RS06735	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCER98_RS06740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BCER98_RS06745	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BCER98_RS06750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCER98_RS06750	COG1199	ATP-dependent helicase activity
BCER98_RS06765	COG3935	DnaD domain protein
BCER98_RS06770	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCER98_RS06780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCER98_RS06780	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCER98_RS06785	COG3331	DNA recombination
BCER98_RS06820	COG4474	Belongs to the UPF0398 family
BCER98_RS06825	COG3599	regulation of cell shape
BCER98_RS06830	COG0116	Belongs to the methyltransferase superfamily
BCER98_RS06835	COG4974	Belongs to the 'phage' integrase family
BCER98_RS06920	COG1199	ATP-dependent helicase activity
BCER98_RS06925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BCER98_RS06930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCER98_RS06935	COG2233	PERMEase
BCER98_RS06940	COG2311	Membrane
BCER98_RS06945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BCER98_RS06955	COG0456	acetyltransferase
BCER98_RS06985	COG3766	membrane
BCER98_RS06995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCER98_RS07000	COG1733	regulation of RNA biosynthetic process
BCER98_RS07020	COG0328	RNA-DNA hybrid ribonuclease activity
BCER98_RS07045	COG1278	Cold shock
BCER98_RS07055	COG3162	membrane
BCER98_RS07060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS07065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCER98_RS07070	COG0475	glutathione-regulated potassium exporter activity
BCER98_RS07075	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCER98_RS07080	COG2323	membrane
BCER98_RS07085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BCER98_RS07105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCER98_RS07115	COG2201	protein-glutamate methylesterase activity
BCER98_RS07120	COG0643	Histidine kinase
BCER98_RS07120	COG2198	Histidine kinase
BCER98_RS07125	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCER98_RS07125	COG1776	CheC inhibitor of MCP methylation
BCER98_RS07140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BCER98_RS07160	COG1256	bacterial-type flagellum assembly
BCER98_RS07165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCER98_RS07185	COG1815	bacterial-type flagellum-dependent cell motility
BCER98_RS07190	COG1558	bacterial-type flagellum-dependent cell motility
BCER98_RS07205	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCER98_RS07215	COG1157	protein secretion by the type III secretion system
BCER98_RS07250	COG0835	chemotaxis
BCER98_RS07250	COG0784	Response regulator, receiver
BCER98_RS07260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCER98_RS07280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BCER98_RS07285	COG0741	lytic transglycosylase activity
BCER98_RS07295	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCER98_RS07300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BCER98_RS07300	COG1776	CheC inhibitor of MCP methylation
BCER98_RS07310	COG1338	Plays a role in the flagellum-specific transport system
BCER98_RS07315	COG1987	bacterial-type flagellum assembly
BCER98_RS07325	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCER98_RS07330	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BCER98_RS07335	COG1419	protein localization to endoplasmic reticulum
BCER98_RS07340	COG4786	Flagellar basal body rod
BCER98_RS07345	COG1136	(ABC) transporter
BCER98_RS07345	COG0577	efflux transmembrane transporter activity
BCER98_RS07370	COG1309	transcriptional regulator
BCER98_RS07385	COG2814	Major facilitator Superfamily
BCER98_RS07430	COG0367	asparagine synthase
BCER98_RS07450	COG1802	Transcriptional regulator
BCER98_RS07455	COG0697	spore germination
BCER98_RS07465	COG1757	Na H antiporter
BCER98_RS07495	COG0534	Mate efflux family protein
BCER98_RS07500	COG3340	Belongs to the peptidase S51 family
BCER98_RS07505	COG2733	membrane
BCER98_RS07510	COG1280	lysine exporter protein (LysE YggA)
BCER98_RS07515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCER98_RS07520	COG2502	aspartate--ammonia ligase
BCER98_RS07525	COG1309	transcriptional regulator
BCER98_RS07530	COG0109	protoheme IX farnesyltransferase activity
BCER98_RS07555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCER98_RS07560	COG0488	(ABC) transporter
BCER98_RS07565	COG4166	transmembrane transport
BCER98_RS07570	COG2223	nitrite transmembrane transporter activity
BCER98_RS07575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCER98_RS07580	COG2244	polysaccharide biosynthetic process
BCER98_RS07585	COG0733	neurotransmitter:sodium symporter activity
BCER98_RS07590	COG5566	PFAM Mor transcription activator
BCER98_RS07600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCER98_RS07605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCER98_RS07610	COG0129	dihydroxy-acid dehydratase activity
BCER98_RS07615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCER98_RS07630	COG0745	RESPONSE REGULATOR receiver
BCER98_RS07645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCER98_RS07650	COG2814	Major facilitator Superfamily
BCER98_RS07655	COG3384	dioxygenase
BCER98_RS07675	COG0402	S-adenosylhomocysteine deaminase activity
BCER98_RS07680	COG4166	transmembrane transport
BCER98_RS07690	COG1914	H( )-stimulated, divalent metal cation uptake system
BCER98_RS07695	COG1054	Belongs to the UPF0176 family
BCER98_RS07705	COG0083	homoserine kinase activity
BCER98_RS07715	COG2390	Transcriptional regulator
BCER98_RS07720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BCER98_RS07735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCER98_RS07745	COG1510	regulation of RNA biosynthetic process
BCER98_RS07750	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS07755	COG1454	alcohol dehydrogenase
BCER98_RS07770	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS07775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BCER98_RS07785	COG0628	permease
BCER98_RS07795	COG0523	cobalamin synthesis protein
BCER98_RS07820	COG1686	Belongs to the peptidase S11 family
BCER98_RS07835	COG1388	LysM domain
BCER98_RS07835	COG0791	NLP P60 protein
BCER98_RS07840	COG0300	oxidoreductase activity
BCER98_RS07845	COG0460	homoserine dehydrogenase
BCER98_RS07855	COG0083	homoserine kinase activity
BCER98_RS07860	COG1316	TRANSCRIPTIONal
BCER98_RS07875	COG1285	pathogenesis
BCER98_RS07880	COG1247	-acetyltransferase
BCER98_RS07910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCER98_RS07915	COG0577	efflux transmembrane transporter activity
BCER98_RS07920	COG2409	Drug exporters of the RND superfamily
BCER98_RS07925	COG1404	Belongs to the peptidase S8 family
BCER98_RS07940	COG0840	transmembrane signaling receptor activity
BCER98_RS07955	COG3949	Membrane
BCER98_RS07960	COG0783	Belongs to the Dps family
BCER98_RS07980	COG0523	cobalamin synthesis protein
BCER98_RS07990	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCER98_RS08005	COG1902	pentaerythritol trinitrate reductase activity
BCER98_RS08010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCER98_RS08020	COG4166	transmembrane transport
BCER98_RS08025	COG0346	lactoylglutathione lyase activity
BCER98_RS08035	COG5337	Spore coat protein CotH
BCER98_RS08040	COG1051	belongs to the nudix hydrolase family
BCER98_RS08045	COG0586	Pfam SNARE associated Golgi protein
BCER98_RS08050	COG2244	polysaccharide biosynthetic process
BCER98_RS08060	COG0701	Predicted permease
BCER98_RS08065	COG3689	TIGRFAM TIGR03943 family protein
BCER98_RS08070	COG1607	acyl-coa hydrolase
BCER98_RS08075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCER98_RS08085	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS08095	COG2839	Protein conserved in bacteria
BCER98_RS08100	COG1253	flavin adenine dinucleotide binding
BCER98_RS08115	COG1114	Component of the transport system for branched-chain amino acids
BCER98_RS08125	COG0860	N-Acetylmuramoyl-L-alanine amidase
BCER98_RS08135	COG1876	peptidase activity
BCER98_RS08165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCER98_RS08170	COG1819	glycosyl
BCER98_RS08175	COG1819	glycosyl
BCER98_RS08180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCER98_RS08225	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCER98_RS08280	COG3874	Sporulation protein YtfJ
BCER98_RS08305	COG2226	methyltransferase
BCER98_RS08330	COG0386	Belongs to the glutathione peroxidase family
BCER98_RS08360	COG0640	Transcriptional regulator
BCER98_RS08365	COG0798	PFAM Bile acid sodium symporter
BCER98_RS08370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCER98_RS08410	COG1418	mRNA catabolic process
BCER98_RS08415	COG0488	(ABC) transporter
BCER98_RS08425	COG0629	single-stranded DNA binding
BCER98_RS08430	COG1413	lyase activity
BCER98_RS08445	COG2521	methyltransferase
BCER98_RS08445	COG2136	Putative SAM-dependent methyltransferase
BCER98_RS08450	COG0018	arginyl-trna synthetase
BCER98_RS08460	COG0733	neurotransmitter:sodium symporter activity
BCER98_RS08465	COG0596	Alpha beta hydrolase
BCER98_RS08470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCER98_RS08475	COG0477	Major facilitator Superfamily
BCER98_RS08485	COG1454	alcohol dehydrogenase
BCER98_RS08490	COG2610	gluconate transmembrane transporter activity
BCER98_RS08500	COG0456	acetyltransferase
BCER98_RS08505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BCER98_RS08515	COG1131	(ABC) transporter
BCER98_RS08520	COG4473	ABC transporter
BCER98_RS08535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCER98_RS08540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BCER98_RS08550	COG0768	penicillin binding
BCER98_RS08560	COG0204	Acyl-transferase
BCER98_RS08565	COG1272	protein, Hemolysin III
BCER98_RS08570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCER98_RS08575	COG0805	protein transport
BCER98_RS08585	COG1307	EDD domain protein, DegV family
BCER98_RS08595	COG1999	signal sequence binding
BCER98_RS08600	COG0071	Belongs to the small heat shock protein (HSP20) family
BCER98_RS08605	COG0367	asparagine synthase
BCER98_RS08615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCER98_RS08640	COG0071	Belongs to the small heat shock protein (HSP20) family
BCER98_RS08645	COG1737	Transcriptional regulator
BCER98_RS08650	COG1070	Carbohydrate kinase
BCER98_RS08660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCER98_RS08715	COG1151	hydroxylamine reductase activity
BCER98_RS08725	COG1253	flavin adenine dinucleotide binding
BCER98_RS08730	COG5506	Protein of unknown function (DUF1694)
BCER98_RS08750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCER98_RS08755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BCER98_RS08760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BCER98_RS08765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCER98_RS08770	COG0456	acetyltransferase
BCER98_RS08775	COG3829	transcription factor binding
BCER98_RS08780	COG1509	lysine 2,3-aminomutase activity
BCER98_RS08790	COG4479	Belongs to the UPF0346 family
BCER98_RS08795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCER98_RS08815	COG1357	PFAM Pentapeptide repeats (8 copies)
BCER98_RS08815	COG0515	serine threonine protein kinase
BCER98_RS08820	COG0671	phosphoesterase, PA-phosphatase related
BCER98_RS08825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCER98_RS08830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCER98_RS08860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BCER98_RS08870	COG0726	polysaccharide deacetylase
BCER98_RS08875	COG1408	metallophosphoesterase
BCER98_RS08880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCER98_RS08885	COG2323	membrane
BCER98_RS08890	COG0671	phosphoesterase, PA-phosphatase related
BCER98_RS08900	COG1280	lysine exporter protein (LysE YggA)
BCER98_RS08905	COG3403	YqcI/YcgG family
BCER98_RS08930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCER98_RS08930	COG4499	WXG100 protein secretion system (Wss), protein YukC
BCER98_RS08940	COG0372	Belongs to the citrate synthase family
BCER98_RS08945	COG2079	MmgE PrpD family protein
BCER98_RS08950	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCER98_RS08955	COG1960	acyl-CoA dehydrogenase activity
BCER98_RS08960	COG2084	Dehydrogenase
BCER98_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS08975	COG1280	lysine exporter protein (LysE YggA)
BCER98_RS08995	COG0420	3'-5' exonuclease activity
BCER98_RS09000	COG0419	ATPase involved in DNA repair
BCER98_RS09005	COG3104	oligopeptide transport
BCER98_RS09025	COG1131	(ABC) transporter
BCER98_RS09045	COG1131	(ABC) transporter
BCER98_RS09050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCER98_RS09065	COG1942	4-Oxalocrotonate Tautomerase
BCER98_RS09080	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS09085	COG1169	isochorismate synthase
BCER98_RS09090	COG1021	2,3-dihydroxybenzoate-AMP ligase
BCER98_RS09095	COG3433	isochorismatase activity
BCER98_RS09095	COG1535	isochorismatase
BCER98_RS09100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCER98_RS09105	COG3251	PFAM MbtH domain protein
BCER98_RS09110	COG2814	Major facilitator Superfamily
BCER98_RS09125	COG0776	regulation of translation
BCER98_RS09140	COG2329	Antibiotic biosynthesis monooxygenase
BCER98_RS09145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCER98_RS09175	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BCER98_RS09180	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BCER98_RS09185	COG0667	Aldo Keto reductase
BCER98_RS09205	COG0010	Belongs to the arginase family
BCER98_RS09215	COG1132	(ABC) transporter
BCER98_RS09220	COG1132	(ABC) transporter
BCER98_RS09250	COG1649	PFAM Uncharacterised BCR, COG1649
BCER98_RS09265	COG2971	BadF BadG BcrA BcrD
BCER98_RS09285	COG0588	phosphoglycerate mutase activity
BCER98_RS09315	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCER98_RS09325	COG1960	acyl-CoA dehydrogenase activity
BCER98_RS09330	COG0439	Biotin carboxylase
BCER98_RS09335	COG0511	ligase activity, forming carbon-carbon bonds
BCER98_RS09340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCER98_RS09345	COG1024	Enoyl-CoA hydratase
BCER98_RS09350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCER98_RS09355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCER98_RS09365	COG1216	Glycosyl transferase, family 2
BCER98_RS09370	COG0640	Transcriptional regulator
BCER98_RS09380	COG1686	Belongs to the peptidase S11 family
BCER98_RS09385	COG5002	protein histidine kinase activity
BCER98_RS09415	COG0789	Transcriptional regulator
BCER98_RS09430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCER98_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS09480	COG1309	transcriptional regulator
BCER98_RS09495	COG2002	toxin-antitoxin pair type II binding
BCER98_RS09515	COG0693	protein deglycase activity
BCER98_RS09520	COG0201	protein transport
BCER98_RS09540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCER98_RS09545	COG0322	excinuclease ABC activity
BCER98_RS09555	COG4667	esterase of the alpha-beta hydrolase superfamily
BCER98_RS09585	COG2223	nitrite transmembrane transporter activity
BCER98_RS09625	COG1216	Glycosyl transferase, family 2
BCER98_RS09640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCER98_RS09645	COG1279	arginine transmembrane transporter activity
BCER98_RS09675	COG1794	racemase activity, acting on amino acids and derivatives
BCER98_RS09685	COG2828	Protein conserved in bacteria
BCER98_RS09690	COG5002	protein histidine kinase activity
BCER98_RS09695	COG0561	phosphatase activity
BCER98_RS09710	COG2124	cytochrome p450
BCER98_RS09745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BCER98_RS09750	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS09755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCER98_RS09765	COG2959	enzyme of heme biosynthesis
BCER98_RS09795	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BCER98_RS09800	COG3844	kynureninase activity
BCER98_RS09810	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS09820	COG4176	ABC-type proline glycine betaine transport system permease component
BCER98_RS09825	COG0517	IMP dehydrogenase activity
BCER98_RS09825	COG4175	Glycine betaine
BCER98_RS09850	COG2153	protein acetylation
BCER98_RS09880	COG0514	ATP-dependent DNA helicase (RecQ)
BCER98_RS09895	COG4637	Psort location Cytoplasmic, score
BCER98_RS09900	COG1227	inorganic diphosphatase activity
BCER98_RS09905	COG3397	chitin binding
BCER98_RS09945	COG4166	transmembrane transport
BCER98_RS09955	COG4948	Mandelate Racemase Muconate Lactonizing
BCER98_RS09990	COG1131	(ABC) transporter
BCER98_RS09995	COG1994	Peptidase M50
BCER98_RS10000	COG2963	transposase activity
BCER98_RS10005	COG2801	Transposase and inactivated derivatives
BCER98_RS10035	COG1307	EDD domain protein, DegV family
BCER98_RS10085	COG5444	nuclease activity
BCER98_RS10165	COG2261	transglycosylase associated protein
BCER98_RS10195	COG0436	Aminotransferase
BCER98_RS10210	COG3973	AAA domain
BCER98_RS10215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCER98_RS10235	COG0628	permease
BCER98_RS10245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCER98_RS10250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCER98_RS10255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCER98_RS10270	COG2746	aminoglycoside 3-N-acetyltransferase activity
BCER98_RS10285	COG0456	acetyltransferase
BCER98_RS10285	COG0454	-acetyltransferase
BCER98_RS10310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCER98_RS10315	COG1368	sulfuric ester hydrolase activity
BCER98_RS10320	COG0488	(ABC) transporter
BCER98_RS10325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCER98_RS10325	COG1605	Chorismate mutase
BCER98_RS10345	COG0346	lactoylglutathione lyase activity
BCER98_RS10350	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BCER98_RS10390	COG2329	Antibiotic biosynthesis monooxygenase
BCER98_RS10405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCER98_RS10430	COG0494	nUDIX hydrolase
BCER98_RS10445	COG0456	acetyltransferase
BCER98_RS10465	COG0697	spore germination
BCER98_RS10470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCER98_RS10480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BCER98_RS10495	COG0730	response to heat
BCER98_RS10500	COG0833	amino acid
BCER98_RS10525	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BCER98_RS10540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BCER98_RS10545	COG1984	allophanate hydrolase subunit 2
BCER98_RS10550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BCER98_RS10555	COG1414	Transcriptional regulator
BCER98_RS10570	COG1960	acyl-CoA dehydrogenase activity
BCER98_RS10585	COG3314	Sporulation integral membrane protein YlbJ
BCER98_RS10600	COG0346	lactoylglutathione lyase activity
BCER98_RS10605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCER98_RS10610	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCER98_RS10615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCER98_RS10620	COG0438	transferase activity, transferring glycosyl groups
BCER98_RS10635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCER98_RS10640	COG0438	transferase activity, transferring glycosyl groups
BCER98_RS10645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCER98_RS10655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCER98_RS10675	COG4851	CamS sex pheromone cAM373 precursor
BCER98_RS10730	COG0477	Major facilitator Superfamily
BCER98_RS10745	COG1846	Transcriptional regulator
BCER98_RS10750	COG2814	Major facilitator Superfamily
BCER98_RS10760	COG2031	fatty acid transporter
BCER98_RS10795	COG1122	ATPase activity
BCER98_RS10820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCER98_RS10835	COG1131	(ABC) transporter
BCER98_RS10855	COG2365	Tyrosine phosphatase family
BCER98_RS10885	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BCER98_RS10890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS10895	COG0579	oxidoreductase
BCER98_RS10900	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BCER98_RS10910	COG1253	flavin adenine dinucleotide binding
BCER98_RS10915	COG0789	Transcriptional regulator
BCER98_RS10920	COG3813	Protein conserved in bacteria
BCER98_RS10935	COG0384	phenazine biosynthesis protein PhzF
BCER98_RS10965	COG1132	(ABC) transporter
BCER98_RS10970	COG1132	(ABC) transporter
BCER98_RS10990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCER98_RS11030	COG2801	Transposase and inactivated derivatives
BCER98_RS11035	COG2963	transposase activity
BCER98_RS11040	COG0577	efflux transmembrane transporter activity
BCER98_RS11040	COG1136	(ABC) transporter
BCER98_RS11160	COG2072	flavoprotein involved in K transport
BCER98_RS11185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCER98_RS11190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCER98_RS11200	COG1193	negative regulation of DNA recombination
BCER98_RS11205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BCER98_RS11210	COG1164	Oligoendopeptidase f
BCER98_RS11230	COG0584	glycerophosphoryl diester phosphodiesterase
BCER98_RS11235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCER98_RS11265	COG3397	chitin binding
BCER98_RS11275	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BCER98_RS11280	COG0277	FAD linked oxidase domain protein
BCER98_RS11285	COG1285	pathogenesis
BCER98_RS11290	COG2720	vancomycin resistance protein
BCER98_RS11310	COG1278	Cold shock
BCER98_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS11325	COG0165	Argininosuccinate lyase
BCER98_RS11340	COG4145	pantothenate transmembrane transporter activity
BCER98_RS11350	COG1012	belongs to the aldehyde dehydrogenase family
BCER98_RS11360	COG1657	PFAM Prenyltransferase squalene oxidase
BCER98_RS11365	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BCER98_RS11370	COG2962	Rard protein
BCER98_RS11405	COG2226	methyltransferase
BCER98_RS11410	COG4166	transmembrane transport
BCER98_RS11415	COG4166	transmembrane transport
BCER98_RS11420	COG1301	dicarboxylic acid transport
BCER98_RS11425	COG0673	inositol 2-dehydrogenase activity
BCER98_RS11430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCER98_RS11435	COG0187	DNA topoisomerase II activity
BCER98_RS11440	COG1832	CoA-binding protein
BCER98_RS11445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCER98_RS11450	COG0745	RESPONSE REGULATOR receiver
BCER98_RS11465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BCER98_RS11470	COG4841	protein insertion into membrane
BCER98_RS11475	COG0824	Thioesterase
BCER98_RS11500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCER98_RS11505	COG3655	Transcriptional regulator
BCER98_RS11520	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCER98_RS11560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCER98_RS11565	COG0318	PFAM AMP-dependent synthetase and ligase
BCER98_RS11595	COG0457	Tetratricopeptide repeat
BCER98_RS11600	COG2801	Transposase and inactivated derivatives
BCER98_RS11630	COG2963	transposase activity
BCER98_RS11635	COG2801	Transposase and inactivated derivatives
BCER98_RS11680	COG2826	transposase and inactivated derivatives, IS30 family
BCER98_RS11695	COG0534	Mate efflux family protein
BCER98_RS11725	COG3023	N-Acetylmuramoyl-L-alanine amidase
BCER98_RS11735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS11745	COG5002	protein histidine kinase activity
BCER98_RS11750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCER98_RS11755	COG0010	Belongs to the arginase family
BCER98_RS11760	COG1228	amidohydrolase
BCER98_RS11765	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BCER98_RS11770	COG2986	histidine ammonia-lyase
BCER98_RS11790	COG4846	Membrane protein involved in cytochrome C biogenesis
BCER98_RS11795	COG0785	Cytochrome C biogenesis protein
BCER98_RS11805	COG1473	amidohydrolase
BCER98_RS11810	COG0583	DNA-binding transcription factor activity
BCER98_RS11815	COG1380	Effector of murein hydrolase LrgA
BCER98_RS11820	COG1346	cytolysis
BCER98_RS11825	COG4187	Peptidase family M20/M25/M40
BCER98_RS11835	COG0833	amino acid
BCER98_RS11845	COG0730	response to heat
BCER98_RS11855	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCER98_RS11855	COG3409	Peptidoglycan-binding domain 1 protein
BCER98_RS11870	COG1132	(ABC) transporter
BCER98_RS11875	COG1132	(ABC) transporter
BCER98_RS11880	COG3763	UPF0154 protein
BCER98_RS11895	COG3639	organic phosphonate transmembrane transporter activity
BCER98_RS11900	COG3639	organic phosphonate transmembrane transporter activity
BCER98_RS11915	COG0737	Belongs to the 5'-nucleotidase family
BCER98_RS11920	COG4224	UPF0291 protein
BCER98_RS11925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCER98_RS11930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCER98_RS11945	COG1695	Transcriptional regulator
BCER98_RS11985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCER98_RS12000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCER98_RS12010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCER98_RS12030	COG0730	response to heat
BCER98_RS12085	COG0174	glutamine synthetase
BCER98_RS12090	COG0789	Transcriptional regulator
BCER98_RS12095	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BCER98_RS12100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCER98_RS12105	COG2860	membrane
BCER98_RS12110	COG0464	growth
BCER98_RS12125	COG1923	regulation of RNA biosynthetic process
BCER98_RS12130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCER98_RS12140	COG1388	LysM domain
BCER98_RS12140	COG3584	3D domain protein
BCER98_RS12145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCER98_RS12145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BCER98_RS12145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCER98_RS12150	COG1105	Belongs to the carbohydrate kinase PfkB family
BCER98_RS12155	COG1349	DNA-binding transcription factor activity
BCER98_RS12160	COG2322	membrane
BCER98_RS12180	COG2116	formate transmembrane transporter activity
BCER98_RS12190	COG1937	Protein conserved in bacteria
BCER98_RS12195	COG2819	hydrolase of the alpha beta superfamily
BCER98_RS12200	COG1120	ATPase activity
BCER98_RS12205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS12210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS12215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCER98_RS12220	COG2706	6-phosphogluconolactonase activity
BCER98_RS12225	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCER98_RS12235	COG0346	lactoylglutathione lyase activity
BCER98_RS12245	COG1113	amino acid transport
BCER98_RS12260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BCER98_RS12265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BCER98_RS12275	COG4550	Control of competence regulator ComK, YlbF/YmcA
BCER98_RS12280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCER98_RS12285	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCER98_RS12290	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCER98_RS12290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCER98_RS12300	COG2359	stage V sporulation protein S
BCER98_RS12305	COG1692	metallophosphoesterase
BCER98_RS12310	COG1418	mRNA catabolic process
BCER98_RS12315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCER98_RS12320	COG1546	Belongs to the CinA family
BCER98_RS12320	COG1058	Belongs to the CinA family
BCER98_RS12325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCER98_RS12330	COG1426	Protein conserved in bacteria
BCER98_RS12345	COG0300	oxidoreductase activity
BCER98_RS12350	COG0612	Peptidase, M16
BCER98_RS12355	COG0612	Peptidase, M16
BCER98_RS12360	COG1079	Belongs to the binding-protein-dependent transport system permease family
BCER98_RS12365	COG4603	Belongs to the binding-protein-dependent transport system permease family
BCER98_RS12370	COG3845	ABC transporter
BCER98_RS12375	COG1744	ABC transporter substrate-binding protein PnrA-like
BCER98_RS12380	COG2188	Transcriptional regulator
BCER98_RS12385	COG1674	ftsk spoiiie
BCER98_RS12400	COG0740	serine-type endopeptidase activity
BCER98_RS12405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCER98_RS12420	COG0527	aspartate kinase activity
BCER98_RS12425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BCER98_RS12430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCER98_RS12435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCER98_RS12440	COG1873	PFAM PRC-barrel domain
BCER98_RS12445	COG0612	Peptidase, M16
BCER98_RS12450	COG0726	polysaccharide deacetylase
BCER98_RS12455	COG1185	polyribonucleotide nucleotidyltransferase activity
BCER98_RS12465	COG0196	riboflavin kinase activity
BCER98_RS12470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCER98_RS12475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCER98_RS12480	COG1550	Protein conserved in bacteria
BCER98_RS12485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCER98_RS12490	COG1358	cellular component organization or biogenesis
BCER98_RS12495	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BCER98_RS12500	COG0195	Participates in both transcription termination and antitermination
BCER98_RS12505	COG0779	Required for maturation of 30S ribosomal subunits
BCER98_RS12515	COG0442	prolyl-tRNA aminoacylation
BCER98_RS12520	COG0750	zinc metalloprotease
BCER98_RS12530	COG4589	Belongs to the CDS family
BCER98_RS12540	COG0233	cytoplasmic translational termination
BCER98_RS12545	COG0528	UMP kinase activity
BCER98_RS12550	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCER98_RS12555	COG0052	Belongs to the universal ribosomal protein uS2 family
BCER98_RS12560	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BCER98_RS12565	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BCER98_RS12570	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BCER98_RS12575	COG4974	Belongs to the 'phage' integrase family
BCER98_RS12580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BCER98_RS12585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCER98_RS12590	COG0758	DNA mediated transformation
BCER98_RS12595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCER98_RS12600	COG0045	succinate-CoA ligase (ADP-forming) activity
BCER98_RS12605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCER98_RS12620	COG0335	large ribosomal subunit rRNA binding
BCER98_RS12625	COG0336	Belongs to the RNA methyltransferase TrmD family
BCER98_RS12630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCER98_RS12635	COG1837	Belongs to the UPF0109 family
BCER98_RS12640	COG0228	four-way junction DNA binding
BCER98_RS12645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCER98_RS12650	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BCER98_RS12655	COG0552	protein localization to endoplasmic reticulum
BCER98_RS12660	COG1196	nuclear chromosome segregation
BCER98_RS12665	COG0571	ribonuclease III activity
BCER98_RS12670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCER98_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS12680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BCER98_RS12685	COG0416	fatty acid biosynthetic process
BCER98_RS12690	COG2050	protein possibly involved in aromatic compounds catabolism
BCER98_RS12690	COG1349	DNA-binding transcription factor activity
BCER98_RS12695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCER98_RS12700	COG1461	Dihydroxyacetone kinase
BCER98_RS12705	COG1302	Protein conserved in bacteria
BCER98_RS12710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCER98_RS12720	COG1564	THIamine pyrophosphokinase
BCER98_RS12725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCER98_RS12730	COG1162	GTPase activity
BCER98_RS12735	COG0515	serine threonine protein kinase
BCER98_RS12735	COG2815	serine threonine protein kinase
BCER98_RS12740	COG0631	protein serine/threonine phosphatase activity
BCER98_RS12745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCER98_RS12750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BCER98_RS12750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCER98_RS12755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCER98_RS12760	COG0242	peptide deformylase activity
BCER98_RS12765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCER98_RS12770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCER98_RS12775	COG1758	RNA polymerase activity
BCER98_RS12790	COG1561	YicC-like family, N-terminal region
BCER98_RS12795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCER98_RS12810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCER98_RS12815	COG0284	orotidine-5'-phosphate decarboxylase activity
BCER98_RS12820	COG0167	dihydroorotate dehydrogenase activity
BCER98_RS12825	COG0543	2 iron, 2 sulfur cluster binding
BCER98_RS12830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCER98_RS12840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCER98_RS12845	COG0540	Belongs to the ATCase OTCase family
BCER98_RS12855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BCER98_RS12860	COG0564	pseudouridine synthase activity
BCER98_RS12865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCER98_RS12875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BCER98_RS12880	COG3599	regulation of cell shape
BCER98_RS12885	COG2302	S4 RNA-binding domain
BCER98_RS12890	COG0762	integral membrane protein
BCER98_RS12895	COG1799	cell septum assembly
BCER98_RS12900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BCER98_RS12910	COG1873	PFAM PRC-barrel domain
BCER98_RS12915	COG1191	sigma factor activity
BCER98_RS12920	COG1191	sigma factor activity
BCER98_RS12930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCER98_RS12935	COG0849	cell division
BCER98_RS12940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BCER98_RS12950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCER98_RS12955	COG0772	Belongs to the SEDS family
BCER98_RS12960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCER98_RS12965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCER98_RS12970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCER98_RS12975	COG0768	penicillin binding
BCER98_RS12980	COG0768	penicillin binding
BCER98_RS12985	COG4839	cell division protein FtsL
BCER98_RS12990	COG0275	rRNA processing
BCER98_RS12995	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BCER98_RS13000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BCER98_RS13005	COG0454	-acetyltransferase
BCER98_RS13015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCER98_RS13020	COG1399	metal-binding, possibly nucleic acid-binding protein
BCER98_RS13130	COG4626	Terminase
BCER98_RS13130	COG1802	Transcriptional regulator
BCER98_RS13215	COG0756	dUTP diphosphatase activity
BCER98_RS13245	COG3723	Recombinational DNA repair protein, rece pathway
BCER98_RS13255	COG5377	YqaJ viral recombinase family
BCER98_RS13295	COG0582	viral genome integration into host DNA
BCER98_RS13300	COG1323	Belongs to the UPF0348 family
BCER98_RS13305	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCER98_RS13310	COG1752	Esterase of the alpha-beta hydrolase superfamily
BCER98_RS13315	COG3314	Sporulation integral membrane protein YlbJ
BCER98_RS13320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCER98_RS13325	COG0742	ribosomal rna small subunit methyltransferase
BCER98_RS13335	COG4471	UPF0298 protein
BCER98_RS13340	COG3679	Belongs to the UPF0342 family
BCER98_RS13345	COG0406	alpha-ribazole phosphatase activity
BCER98_RS13360	COG2340	Cysteine-rich secretory protein family
BCER98_RS13370	COG3336	cytochrome c oxidase
BCER98_RS13395	COG0109	protoheme IX farnesyltransferase activity
BCER98_RS13400	COG1612	heme a metabolic process
BCER98_RS13405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BCER98_RS13410	COG0772	Belongs to the SEDS family
BCER98_RS13415	COG4838	Belongs to the UPF0358 family
BCER98_RS13420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCER98_RS13425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCER98_RS13435	COG4896	Protein conserved in bacteria
BCER98_RS13450	COG1217	gtp-binding protein TYPA
BCER98_RS13460	COG0483	inositol monophosphate 1-phosphatase activity
BCER98_RS13470	COG4493	Belongs to the UPF0637 family
BCER98_RS13475	COG4476	Belongs to the UPF0223 family
BCER98_RS13480	COG1982	Orn Lys Arg decarboxylase major
BCER98_RS13520	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCER98_RS13530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCER98_RS13540	COG0242	peptide deformylase activity
BCER98_RS13545	COG0561	phosphatase activity
BCER98_RS13550	COG5503	Protein of unknown function (DUF1447)
BCER98_RS13555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCER98_RS13560	COG0569	domain protein
BCER98_RS13570	COG1473	amidohydrolase
BCER98_RS13575	COG2171	N-acyltransferase activity
BCER98_RS13580	COG0583	DNA-binding transcription factor activity
BCER98_RS13585	COG0517	IMP dehydrogenase activity
BCER98_RS13595	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BCER98_RS13600	COG4703	Protein of unknown function (DUF1797)
BCER98_RS13615	COG2200	EAL domain
BCER98_RS13620	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS13625	COG1408	metallophosphoesterase
BCER98_RS13635	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCER98_RS13675	COG2814	Major facilitator Superfamily
BCER98_RS13680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BCER98_RS13690	COG3209	COG3209 Rhs family protein
BCER98_RS13700	COG2205	protein histidine kinase activity
BCER98_RS13710	COG0436	Aminotransferase
BCER98_RS13715	COG1609	Transcriptional regulator
BCER98_RS13720	COG3833	ABC-type maltose transport systems, permease component
BCER98_RS13725	COG1175	transmembrane transport
BCER98_RS13730	COG2182	Extracellular solute-binding protein
BCER98_RS13740	COG0366	Alpha amylase catalytic
BCER98_RS13745	COG3842	ATPase activity
BCER98_RS13770	COG0183	Belongs to the thiolase family
BCER98_RS13795	COG1695	Transcriptional regulator
BCER98_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS13810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BCER98_RS13815	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BCER98_RS13820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCER98_RS13825	COG0436	Aminotransferase
BCER98_RS13830	COG1850	ribulose-bisphosphate carboxylase activity
BCER98_RS13835	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BCER98_RS13840	COG0235	Class ii aldolase
BCER98_RS13845	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BCER98_RS13860	COG2084	Dehydrogenase
BCER98_RS13870	COG2199	diguanylate cyclase activity
BCER98_RS13875	COG0778	Nitroreductase
BCER98_RS13900	COG2190	(PTS) system
BCER98_RS13900	COG1263	PTS System
BCER98_RS13900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCER98_RS13905	COG3711	transcriptional antiterminator
BCER98_RS13915	COG2188	Transcriptional regulator
BCER98_RS13920	COG0363	glucosamine-6-phosphate deaminase activity
BCER98_RS13935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCER98_RS13940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BCER98_RS13945	COG1547	Domain of unknown function (DUF309)
BCER98_RS13955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCER98_RS13960	COG4086	secreted protein
BCER98_RS13965	COG0561	phosphatase activity
BCER98_RS13970	COG0697	spore germination
BCER98_RS13985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCER98_RS14010	COG0733	neurotransmitter:sodium symporter activity
BCER98_RS14020	COG2172	sigma factor antagonist activity
BCER98_RS14030	COG1686	Belongs to the peptidase S11 family
BCER98_RS14035	COG1725	Transcriptional regulator
BCER98_RS14040	COG1131	(ABC) transporter
BCER98_RS14060	COG1846	Transcriptional regulator
BCER98_RS14075	COG0598	Magnesium transport protein CorA
BCER98_RS14105	COG4974	Belongs to the 'phage' integrase family
BCER98_RS14115	COG0735	belongs to the Fur family
BCER98_RS14120	COG1300	Membrane
BCER98_RS14140	COG0667	Aldo Keto reductase
BCER98_RS14145	COG0656	L-ascorbic acid biosynthetic process
BCER98_RS14150	COG0456	acetyltransferase
BCER98_RS14150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCER98_RS14160	COG4085	toxin activity
BCER98_RS14160	COG1525	nuclease
BCER98_RS14160	COG0737	Belongs to the 5'-nucleotidase family
BCER98_RS14170	COG0596	Alpha beta hydrolase
BCER98_RS14175	COG2056	Na+-H+ antiporter family
BCER98_RS14180	COG1609	Transcriptional regulator
BCER98_RS14185	COG0456	acetyltransferase
BCER98_RS14190	COG1073	alpha beta
BCER98_RS14205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCER98_RS14205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCER98_RS14210	COG0307	riboflavin synthase, alpha
BCER98_RS14215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCER98_RS14215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BCER98_RS14230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BCER98_RS14235	COG4106	trans-aconitate 2-methyltransferase activity
BCER98_RS14240	COG0596	Alpha beta hydrolase
BCER98_RS14245	COG0156	8-amino-7-oxononanoate synthase activity
BCER98_RS14255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCER98_RS14265	COG1757	Na H antiporter
BCER98_RS14270	COG0737	Belongs to the 5'-nucleotidase family
BCER98_RS14295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCER98_RS14305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCER98_RS14315	COG0300	oxidoreductase activity
BCER98_RS14320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCER98_RS14325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCER98_RS14330	COG1760	l-serine dehydratase
BCER98_RS14335	COG1760	l-serine dehydratase
BCER98_RS14345	COG1234	tRNA 3'-trailer cleavage
BCER98_RS14365	COG2195	Cleaves the N-terminal amino acid of tripeptides
BCER98_RS14370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCER98_RS14380	COG1376	ErfK ybiS ycfS ynhG family protein
BCER98_RS14385	COG4129	membrane
BCER98_RS14390	COG1126	abc transporter atp-binding protein
BCER98_RS14395	COG0765	amino acid transport
BCER98_RS14400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCER98_RS14415	COG2816	NAD+ diphosphatase activity
BCER98_RS14420	COG0772	Belongs to the SEDS family
BCER98_RS14425	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCER98_RS14430	COG0022	dehydrogenase e1 component
BCER98_RS14435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BCER98_RS14440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCER98_RS14445	COG3426	butyrate kinase activity
BCER98_RS14455	COG0280	phosphate acetyltransferase
BCER98_RS14460	COG3290	protein histidine kinase activity
BCER98_RS14460	COG3829	transcription factor binding
BCER98_RS14470	COG0584	glycerophosphoryl diester phosphodiesterase
BCER98_RS14475	COG0745	RESPONSE REGULATOR receiver
BCER98_RS14480	COG0750	zinc metalloprotease
BCER98_RS14485	COG0497	DNA recombination
BCER98_RS14495	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BCER98_RS14500	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCER98_RS14510	COG1722	exodeoxyribonuclease VII activity
BCER98_RS14515	COG1570	exodeoxyribonuclease VII activity
BCER98_RS14520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCER98_RS14525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCER98_RS14530	COG1302	Protein conserved in bacteria
BCER98_RS14535	COG0439	Biotin carboxylase
BCER98_RS14540	COG0511	ligase activity, forming carbon-carbon bonds
BCER98_RS14585	COG3854	ATPases associated with a variety of cellular activities
BCER98_RS14605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCER98_RS14610	COG0006	proline dipeptidase activity
BCER98_RS14615	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCER98_RS14625	COG3872	metal-dependent enzyme
BCER98_RS14635	COG1321	iron dependent repressor
BCER98_RS14650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCER98_RS14660	COG1609	Transcriptional regulator
BCER98_RS14670	COG2076	Multidrug Resistance protein
BCER98_RS14675	COG2076	Multidrug Resistance protein
BCER98_RS14690	COG1131	(ABC) transporter
BCER98_RS14695	COG1725	Transcriptional regulator
BCER98_RS14710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCER98_RS14715	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCER98_RS14720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCER98_RS14725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCER98_RS14750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCER98_RS14775	COG1459	type II secretion system
BCER98_RS14780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BCER98_RS14800	COG4824	toxin secretion phage lysis holin
BCER98_RS14880	COG3728	DNA packaging
BCER98_RS14885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCER98_RS14990	COG1396	sequence-specific DNA binding
BCER98_RS15030	COG1078	dGTPase activity
BCER98_RS15045	COG1410	methionine synthase
BCER98_RS15045	COG0646	methionine synthase
BCER98_RS15050	COG0646	methionine synthase
BCER98_RS15050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BCER98_RS15055	COG0626	cystathionine gamma-synthase activity
BCER98_RS15060	COG0626	cystathionine gamma-synthase activity
BCER98_RS15075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCER98_RS15085	COG1940	carbohydrate kinase activity
BCER98_RS15090	COG4483	Protein conserved in bacteria
BCER98_RS15095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCER98_RS15100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCER98_RS15105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BCER98_RS15110	COG0704	Plays a role in the regulation of phosphate uptake
BCER98_RS15120	COG0581	inorganic phosphate transmembrane transporter activity
BCER98_RS15125	COG0573	inorganic phosphate transmembrane transporter activity
BCER98_RS15130	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BCER98_RS15135	COG0768	penicillin binding
BCER98_RS15140	COG0477	Major facilitator Superfamily
BCER98_RS15145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCER98_RS15165	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCER98_RS15170	COG0735	belongs to the Fur family
BCER98_RS15175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCER98_RS15180	COG1121	(ABC) transporter
BCER98_RS15185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS15195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BCER98_RS15210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BCER98_RS15215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCER98_RS15220	COG2384	SAM-dependent methyltransferase
BCER98_RS15230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCER98_RS15235	COG0358	DNA primase activity
BCER98_RS15240	COG1671	Belongs to the UPF0178 family
BCER98_RS15245	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BCER98_RS15250	COG0517	IMP dehydrogenase activity
BCER98_RS15255	COG1381	Involved in DNA repair and RecF pathway recombination
BCER98_RS15260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCER98_RS15265	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BCER98_RS15270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCER98_RS15275	COG1480	7TM receptor with intracellular HD hydrolase
BCER98_RS15280	COG1702	phosphate starvation-inducible protein PhoH
BCER98_RS15295	COG1610	YqeY-like protein
BCER98_RS15300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BCER98_RS15305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCER98_RS15310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BCER98_RS15315	COG2264	protein methyltransferase activity
BCER98_RS15320	COG0484	heat shock protein binding
BCER98_RS15325	COG0443	Heat shock 70 kDa protein
BCER98_RS15330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCER98_RS15335	COG1420	regulation of RNA biosynthetic process
BCER98_RS15340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCER98_RS15345	COG1733	regulation of RNA biosynthetic process
BCER98_RS15350	COG0693	protein deglycase activity
BCER98_RS15355	COG0481	GTPase activity
BCER98_RS15365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BCER98_RS15370	COG0268	Binds directly to 16S ribosomal RNA
BCER98_RS15375	COG1466	dna polymerase III delta subunit
BCER98_RS15385	COG0658	competence protein
BCER98_RS15385	COG2333	competence protein COMEC
BCER98_RS15390	COG2131	deaminase
BCER98_RS15395	COG1596	polysaccharide export
BCER98_RS15395	COG1555	photosystem II stabilization
BCER98_RS15400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCER98_RS15405	COG2226	methyltransferase
BCER98_RS15410	COG0799	negative regulation of ribosome biogenesis
BCER98_RS15415	COG1713	HD superfamily hydrolase involved in NAD metabolism
BCER98_RS15420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCER98_RS15425	COG1534	Rna-binding protein
BCER98_RS15430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCER98_RS15435	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BCER98_RS15440	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BCER98_RS15450	COG0688	phosphatidylethanolamine metabolic process
BCER98_RS15465	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCER98_RS15470	COG2357	RelA SpoT domain protein
BCER98_RS15475	COG1785	Belongs to the alkaline phosphatase family
BCER98_RS15480	COG0456	acetyltransferase
BCER98_RS15485	COG2267	carboxylic ester hydrolase activity
BCER98_RS15510	COG3186	Phenylalanine-4-hydroxylase
BCER98_RS15515	COG2154	pterin-4-alpha-carbinolamine dehydratase
BCER98_RS15520	COG2514	catechol 2,3-dioxygenase activity
BCER98_RS15525	COG2259	Doxx family
BCER98_RS15545	COG1609	Transcriptional regulator
BCER98_RS15555	COG0626	cystathionine gamma-synthase activity
BCER98_RS15560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BCER98_RS15565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BCER98_RS15570	COG2226	methyltransferase
BCER98_RS15585	COG0768	penicillin binding
BCER98_RS15595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCER98_RS15600	COG0572	uridine kinase
BCER98_RS15605	COG0826	peptidase U32
BCER98_RS15610	COG0826	peptidase U32
BCER98_RS15615	COG4122	O-methyltransferase activity
BCER98_RS15620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BCER98_RS15630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCER98_RS15635	COG4472	Bacterial protein of unknown function (DUF965)
BCER98_RS15640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCER98_RS15645	COG0628	permease
BCER98_RS15665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCER98_RS15675	COG0482	sulfurtransferase activity
BCER98_RS15680	COG1104	cysteine desulfurase activity
BCER98_RS15685	COG1959	2 iron, 2 sulfur cluster binding
BCER98_RS15690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BCER98_RS15710	COG2207	Transcriptional regulator
BCER98_RS15720	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BCER98_RS15730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCER98_RS15735	COG0124	histidyl-tRNA synthetase
BCER98_RS15755	COG1490	D-aminoacyl-tRNA deacylase activity
BCER98_RS15760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCER98_RS15765	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCER98_RS15770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCER98_RS15770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BCER98_RS15775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BCER98_RS15780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCER98_RS15780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCER98_RS15790	COG2244	polysaccharide biosynthetic process
BCER98_RS15810	COG1862	Preprotein translocase
BCER98_RS15815	COG0343	queuine tRNA-ribosyltransferase activity
BCER98_RS15820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BCER98_RS15830	COG2255	four-way junction helicase activity
BCER98_RS15835	COG0632	four-way junction helicase activity
BCER98_RS15840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BCER98_RS15860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCER98_RS15865	COG0157	Belongs to the NadC ModD family
BCER98_RS15870	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCER98_RS15875	COG1104	cysteine desulfurase activity
BCER98_RS15880	COG1827	regulation of RNA biosynthetic process
BCER98_RS15885	COG2258	MOSC domain
BCER98_RS15890	COG0077	Prephenate dehydratase
BCER98_RS15895	COG0577	efflux transmembrane transporter activity
BCER98_RS15900	COG0577	efflux transmembrane transporter activity
BCER98_RS15905	COG1136	(ABC) transporter
BCER98_RS15910	COG5002	protein histidine kinase activity
BCER98_RS15915	COG0745	RESPONSE REGULATOR receiver
BCER98_RS15925	COG3290	protein histidine kinase activity
BCER98_RS15930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCER98_RS15935	COG2868	ribosomal protein
BCER98_RS15940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCER98_RS15945	COG1530	ribonuclease E activity
BCER98_RS15950	COG1994	Peptidase M50
BCER98_RS15955	COG0739	heme binding
BCER98_RS15960	COG2894	cell division
BCER98_RS15965	COG0850	regulation of cytokinetic process
BCER98_RS15975	COG1792	Involved in formation and maintenance of cell shape
BCER98_RS15980	COG1077	Cell shape determining protein MreB Mrl
BCER98_RS15995	COG0424	maF-like protein
BCER98_RS16005	COG0285	dihydrofolate synthase activity
BCER98_RS16030	COG1388	LysM domain
BCER98_RS16030	COG1388	LysM domain
BCER98_RS16035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCER98_RS16040	COG0113	porphobilinogen synthase activity
BCER98_RS16045	COG1587	Uroporphyrinogen-III synthase
BCER98_RS16050	COG0181	hydroxymethylbilane synthase activity
BCER98_RS16055	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCER98_RS16060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCER98_RS16065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BCER98_RS16075	COG1067	ATP-dependent peptidase activity
BCER98_RS16075	COG0470	DNA polymerase III
BCER98_RS16080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCER98_RS16085	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCER98_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS16110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BCER98_RS16110	COG3321	synthase
BCER98_RS16110	COG4221	oxidoreductase activity
BCER98_RS16125	COG2409	Drug exporters of the RND superfamily
BCER98_RS16125	COG1033	growth of symbiont in host cell
BCER98_RS16135	COG1309	transcriptional regulator
BCER98_RS16155	COG0622	Phosphoesterase
BCER98_RS16165	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BCER98_RS16170	COG5401	PFAM Sporulation and spore germination
BCER98_RS16180	COG2197	response regulator
BCER98_RS16190	COG1959	2 iron, 2 sulfur cluster binding
BCER98_RS16195	COG1668	transmembrane transport
BCER98_RS16200	COG4152	abc transporter atp-binding protein
BCER98_RS16205	COG1360	Flagellar Motor Protein
BCER98_RS16210	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BCER98_RS16215	COG1876	peptidase activity
BCER98_RS16225	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCER98_RS16230	COG1053	succinate dehydrogenase
BCER98_RS16235	COG2009	succinate dehydrogenase
BCER98_RS16240	COG1719	4-vinyl reductase, 4VR
BCER98_RS16255	COG3118	belongs to the thioredoxin family
BCER98_RS16260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCER98_RS16265	COG2086	electron transfer activity
BCER98_RS16270	COG1024	Enoyl-CoA hydratase
BCER98_RS16275	COG1309	transcriptional regulator
BCER98_RS16280	COG0318	PFAM AMP-dependent synthetase and ligase
BCER98_RS16290	COG2318	DinB family
BCER98_RS16305	COG1131	(ABC) transporter
BCER98_RS16310	COG2205	protein histidine kinase activity
BCER98_RS16315	COG0745	RESPONSE REGULATOR receiver
BCER98_RS16320	COG4895	conserved protein (DUF2196)
BCER98_RS16325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BCER98_RS16330	COG1114	Component of the transport system for branched-chain amino acids
BCER98_RS16335	COG1187	pseudouridine synthase activity
BCER98_RS16340	COG1193	negative regulation of DNA recombination
BCER98_RS16345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCER98_RS16345	COG1796	DNA polymerase
BCER98_RS16350	COG1286	toxin biosynthetic process
BCER98_RS16355	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BCER98_RS16360	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCER98_RS16370	COG0017	Asparaginyl-tRNA synthetase
BCER98_RS16380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCER98_RS16385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCER98_RS16395	COG1418	mRNA catabolic process
BCER98_RS16405	COG2814	Major facilitator Superfamily
BCER98_RS16410	COG1566	PFAM secretion protein HlyD family protein
BCER98_RS16415	COG1309	transcriptional regulator
BCER98_RS16420	COG1363	Peptidase, m42
BCER98_RS16430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCER98_RS16435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BCER98_RS16445	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCER98_RS16455	COG1484	DNA-dependent DNA replication
BCER98_RS16460	COG3611	Membrane attachment protein
BCER98_RS16465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BCER98_RS16470	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BCER98_RS16475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCER98_RS16485	COG1971	Probably functions as a manganese efflux pump
BCER98_RS16495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCER98_RS16495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCER98_RS16500	COG5002	protein histidine kinase activity
BCER98_RS16505	COG0745	RESPONSE REGULATOR receiver
BCER98_RS16515	COG0039	L-malate dehydrogenase activity
BCER98_RS16520	COG0538	isocitrate dehydrogenase activity
BCER98_RS16525	COG0372	Belongs to the citrate synthase family
BCER98_RS16530	COG2707	UPF0756 membrane protein
BCER98_RS16535	COG0628	permease
BCER98_RS16540	COG3030	protein affecting phage T7 exclusion by the F plasmid
BCER98_RS16550	COG0205	6-phosphofructokinase activity
BCER98_RS16555	COG0825	malonyl-CoA metabolic process
BCER98_RS16560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BCER98_RS16565	COG1725	Transcriptional regulator
BCER98_RS16570	COG0281	malic enzyme
BCER98_RS16575	COG0587	DNA-directed DNA polymerase activity
BCER98_RS16590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BCER98_RS16600	COG4109	DRTGG domain
BCER98_RS16605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCER98_RS16610	COG0006	proline dipeptidase activity
BCER98_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
BCER98_RS16640	COG0589	response to stress
BCER98_RS16660	COG0165	Argininosuccinate lyase
BCER98_RS16665	COG0137	argininosuccinate synthase activity
BCER98_RS16675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS16685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCER98_RS16690	COG0827	DNA restriction-modification system
BCER98_RS16695	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BCER98_RS16700	COG3874	Sporulation protein YtfJ
BCER98_RS16715	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BCER98_RS16720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCER98_RS16730	COG0301	tRNA thio-modification
BCER98_RS16735	COG1104	cysteine desulfurase activity
BCER98_RS16740	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BCER98_RS16745	COG0583	DNA-binding transcription factor activity
BCER98_RS16750	COG0697	spore germination
BCER98_RS16755	COG1309	transcriptional regulator
BCER98_RS16760	COG1956	GAF domain-containing protein
BCER98_RS16765	COG0626	cystathionine gamma-synthase activity
BCER98_RS16770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCER98_RS16795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCER98_RS16800	COG0454	-acetyltransferase
BCER98_RS16805	COG0517	IMP dehydrogenase activity
BCER98_RS16810	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCER98_RS16815	COG1970	mechanosensitive ion channel activity
BCER98_RS16825	COG1609	Transcriptional regulator
BCER98_RS16830	COG1605	Chorismate mutase
BCER98_RS16830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BCER98_RS16835	COG3118	belongs to the thioredoxin family
BCER98_RS16845	COG2309	aminopeptidase activity
BCER98_RS16855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCER98_RS16860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCER98_RS16870	COG1674	ftsk spoiiie
BCER98_RS16880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCER98_RS16885	COG4848	Belongs to the UPF0354 family
BCER98_RS16890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCER98_RS16895	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BCER98_RS16905	COG0675	Transposase, IS605 OrfB family
BCER98_RS16915	COG1363	Peptidase, m42
BCER98_RS16925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCER98_RS16930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BCER98_RS16940	COG0510	thiamine kinase activity
BCER98_RS16945	COG1523	belongs to the glycosyl hydrolase 13 family
BCER98_RS16955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCER98_RS16960	COG1349	DNA-binding transcription factor activity
BCER98_RS16965	COG1187	pseudouridine synthase activity
BCER98_RS16970	COG2244	polysaccharide biosynthetic process
BCER98_RS16975	COG2081	HI0933 family
BCER98_RS16980	COG2814	Major facilitator Superfamily
BCER98_RS16990	COG3832	glyoxalase III activity
BCER98_RS17060	COG1329	Transcriptional regulator
BCER98_RS17070	COG2223	nitrite transmembrane transporter activity
BCER98_RS17080	COG0314	molybdopterin synthase activity
BCER98_RS17085	COG1763	Mo-molybdopterin cofactor biosynthetic process
BCER98_RS17090	COG0303	'Molybdopterin
BCER98_RS17095	COG0315	cyclic pyranopterin monophosphate synthase activity
BCER98_RS17100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCER98_RS17105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BCER98_RS17110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCER98_RS17115	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BCER98_RS17120	COG1140	nitrate reductase beta subunit
BCER98_RS17125	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCER98_RS17130	COG2181	nitrate reductase activity
BCER98_RS17145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCER98_RS17155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCER98_RS17190	COG0495	leucyl-tRNA aminoacylation
BCER98_RS17195	COG2814	Major facilitator Superfamily
BCER98_RS17205	COG1136	(ABC) transporter
BCER98_RS17210	COG0346	lactoylglutathione lyase activity
BCER98_RS17225	COG1242	4 iron, 4 sulfur cluster binding
BCER98_RS17230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BCER98_RS17235	COG1121	(ABC) transporter
BCER98_RS17245	COG1794	racemase activity, acting on amino acids and derivatives
BCER98_RS17255	COG2378	regulation of single-species biofilm formation
BCER98_RS17265	COG2267	carboxylic ester hydrolase activity
BCER98_RS17270	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BCER98_RS17275	COG0746	molybdenum cofactor guanylyltransferase activity
BCER98_RS17295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCER98_RS17300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BCER98_RS17340	COG2801	Transposase and inactivated derivatives
BCER98_RS17345	COG3409	Peptidoglycan-binding domain 1 protein
BCER98_RS17345	COG5632	N-Acetylmuramoyl-L-alanine amidase
BCER98_RS17355	COG1368	sulfuric ester hydrolase activity
BCER98_RS17370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCER98_RS17375	COG1116	anion transmembrane transporter activity
BCER98_RS17380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCER98_RS17395	COG0494	nUDIX hydrolase
BCER98_RS17405	COG1854	S-ribosylhomocysteine lyase activity
BCER98_RS17410	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BCER98_RS17415	COG0288	reversible hydration of carbon dioxide
BCER98_RS17420	COG1271	oxidase subunit
BCER98_RS17425	COG1294	oxidase, subunit
BCER98_RS17455	COG1842	Phage shock protein A
BCER98_RS17490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BCER98_RS17495	COG1597	lipid kinase activity
BCER98_RS17500	COG1136	(ABC) transporter
BCER98_RS17505	COG0745	RESPONSE REGULATOR receiver
BCER98_RS17510	COG2205	protein histidine kinase activity
BCER98_RS17515	COG0577	efflux transmembrane transporter activity
BCER98_RS17520	COG1136	(ABC) transporter
BCER98_RS17525	COG0577	efflux transmembrane transporter activity
BCER98_RS17530	COG0577	efflux transmembrane transporter activity
BCER98_RS17535	COG4948	Mandelate Racemase Muconate Lactonizing
BCER98_RS17540	COG0318	PFAM AMP-dependent synthetase and ligase
BCER98_RS17545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCER98_RS17550	COG0596	Alpha beta hydrolase
BCER98_RS17555	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BCER98_RS17560	COG1169	isochorismate synthase
BCER98_RS17565	COG1575	Belongs to the MenA family. Type 1 subfamily
BCER98_RS17570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCER98_RS17590	COG0058	SHG alpha-glucan phosphorylase activity
BCER98_RS17595	COG0297	glycogen (starch) synthase activity
BCER98_RS17600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCER98_RS17605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BCER98_RS17610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCER98_RS17710	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCER98_RS17745	COG1285	pathogenesis
BCER98_RS17750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCER98_RS17760	COG0166	Belongs to the GPI family
BCER98_RS17765	COG2155	Conserved Protein
BCER98_RS17770	COG1098	S1 RNA binding domain
BCER98_RS17775	COG0436	Aminotransferase
BCER98_RS17780	COG1522	sequence-specific DNA binding
BCER98_RS17785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BCER98_RS17790	COG2267	carboxylic ester hydrolase activity
BCER98_RS17800	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BCER98_RS17805	COG2032	superoxide dismutase activity
BCER98_RS17815	COG5018	Exonuclease
BCER98_RS17820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BCER98_RS17840	COG2050	protein possibly involved in aromatic compounds catabolism
BCER98_RS17850	COG1268	BioY protein
BCER98_RS17855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BCER98_RS17860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCER98_RS17870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCER98_RS17880	COG3584	3D domain protein
BCER98_RS17900	COG1252	NADH dehydrogenase
BCER98_RS17905	COG0492	ferredoxin-NADP+ reductase activity
BCER98_RS17920	COG1683	Conserved Protein
BCER98_RS17930	COG0316	Belongs to the HesB IscA family
BCER98_RS17935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCER98_RS17940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCER98_RS17950	COG1252	NADH dehydrogenase
BCER98_RS17955	COG2824	Alkylphosphonate utilization operon protein PhnA
BCER98_RS17960	COG3655	Transcriptional regulator
BCER98_RS17975	COG4837	Protein of unknown function (DUF1462)
BCER98_RS17980	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BCER98_RS17985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCER98_RS17990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCER98_RS17995	COG0647	UMP catabolic process
BCER98_RS18005	COG2445	Protein of unknown function DUF86
BCER98_RS18010	COG1494	fructose-1,6-bisphosphatase
BCER98_RS18020	COG4470	Protein conserved in bacteria
BCER98_RS18030	COG0789	Transcriptional regulator
BCER98_RS18035	COG4377	Putative membrane peptidase family (DUF2324)
BCER98_RS18050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCER98_RS18055	COG0739	heme binding
BCER98_RS18065	COG3377	Domain of unknown function (DUF1805)
BCER98_RS18070	COG0737	Belongs to the 5'-nucleotidase family
BCER98_RS18085	COG0719	Fe-S assembly protein
BCER98_RS18090	COG0822	iron-sulfur transferase activity
BCER98_RS18095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCER98_RS18100	COG0719	Fe-S assembly protein
BCER98_RS18105	COG0396	ATPase activity
BCER98_RS18110	COG1464	Belongs to the NlpA lipoprotein family
BCER98_RS18115	COG2011	ABC-type metal ion transport system permease component
BCER98_RS18130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCER98_RS18135	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BCER98_RS18140	COG0509	glycine decarboxylation via glycine cleavage system
BCER98_RS18145	COG1393	Belongs to the ArsC family
BCER98_RS18185	COG1960	acyl-CoA dehydrogenase activity
BCER98_RS18190	COG0183	Belongs to the thiolase family
BCER98_RS18195	COG1024	Enoyl-CoA hydratase
BCER98_RS18195	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCER98_RS18200	COG1686	Belongs to the peptidase S11 family
BCER98_RS18215	COG0011	TIGRFAM Protein of
BCER98_RS18220	COG0840	transmembrane signaling receptor activity
BCER98_RS18230	COG2814	Major facilitator Superfamily
BCER98_RS18235	COG0531	amino acid
BCER98_RS18240	COG0706	membrane insertase activity
BCER98_RS18250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BCER98_RS18260	COG0586	Pfam SNARE associated Golgi protein
BCER98_RS18270	COG1376	ErfK ybiS ycfS ynhG family protein
BCER98_RS18275	COG0745	RESPONSE REGULATOR receiver
BCER98_RS18280	COG5002	protein histidine kinase activity
BCER98_RS18285	COG0840	transmembrane signaling receptor activity
BCER98_RS18290	COG0840	transmembrane signaling receptor activity
BCER98_RS18295	COG2151	metal-sulfur cluster biosynthetic enzyme
BCER98_RS18305	COG1741	Belongs to the pirin family
BCER98_RS18320	COG0783	Belongs to the Dps family
BCER98_RS18325	COG1611	Belongs to the LOG family
BCER98_RS18355	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCER98_RS18360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCER98_RS18365	COG1121	(ABC) transporter
BCER98_RS18390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCER98_RS18395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCER98_RS18400	COG1115	amino acid carrier protein
BCER98_RS18405	COG2910	NAD(P)H-binding
BCER98_RS18420	COG1252	NADH dehydrogenase
BCER98_RS18435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCER98_RS18450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCER98_RS18455	COG4977	sequence-specific DNA binding
BCER98_RS18455	COG1917	Cupin 2, conserved barrel domain protein
BCER98_RS18465	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BCER98_RS18485	COG0697	spore germination
BCER98_RS18495	COG1063	alcohol dehydrogenase
BCER98_RS18505	COG2124	cytochrome p450
BCER98_RS18510	COG0657	acetylesterase activity
BCER98_RS18515	COG2124	cytochrome p450
BCER98_RS18520	COG1309	transcriptional regulator
BCER98_RS18525	COG0657	acetylesterase activity
BCER98_RS18545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCER98_RS18550	COG0557	exoribonuclease II activity
BCER98_RS18555	COG1647	Serine aminopeptidase, S33
BCER98_RS18560	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCER98_RS18565	COG1346	cytolysis
BCER98_RS18575	COG0148	phosphopyruvate hydratase activity
BCER98_RS18580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BCER98_RS18585	COG0149	triose-phosphate isomerase activity
BCER98_RS18590	COG0126	phosphoglycerate kinase activity
BCER98_RS18595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BCER98_RS18610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BCER98_RS18635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCER98_RS18650	COG2323	membrane
BCER98_RS18660	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCER98_RS18665	COG1481	regulation of sporulation
BCER98_RS18670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BCER98_RS18675	COG1660	Displays ATPase and GTPase activities
BCER98_RS18680	COG1051	belongs to the nudix hydrolase family
BCER98_RS18690	COG0492	ferredoxin-NADP+ reductase activity
BCER98_RS18695	COG0457	Tetratricopeptide repeat
BCER98_RS18700	COG0110	maltose O-acetyltransferase activity
BCER98_RS18710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCER98_RS18715	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BCER98_RS18720	COG1950	PFAM Membrane protein of
BCER98_RS18730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCER98_RS18745	COG0789	Transcriptional regulator
BCER98_RS18765	COG0583	DNA-binding transcription factor activity
BCER98_RS18775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCER98_RS18780	COG3409	Peptidoglycan-binding domain 1 protein
BCER98_RS18780	COG0793	Belongs to the peptidase S41A family
BCER98_RS18785	COG2177	Part of the ABC transporter FtsEX involved in
BCER98_RS18790	COG2884	Cell division ATP-binding protein ftsE
BCER98_RS18800	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCER98_RS18815	COG1278	Cold shock
BCER98_RS18820	COG1040	competence protein
BCER98_RS18825	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BCER98_RS18830	COG0791	NLP P60 protein
BCER98_RS18830	COG1388	LysM domain
BCER98_RS18835	COG1733	regulation of RNA biosynthetic process
BCER98_RS18840	COG1307	EDD domain protein, DegV family
BCER98_RS18845	COG1739	Uncharacterized protein family UPF0029
BCER98_RS18850	COG1316	TRANSCRIPTIONal
BCER98_RS18870	COG0457	Tetratricopeptide repeat
BCER98_RS18900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCER98_RS18910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCER98_RS18920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BCER98_RS18920	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BCER98_RS18935	COG1486	melibiose metabolic process
BCER98_RS18940	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCER98_RS18955	COG1447	Phosphotransferase system cellobiose-specific component IIA
BCER98_RS18960	COG1301	dicarboxylic acid transport
BCER98_RS18965	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BCER98_RS18970	COG1271	oxidase subunit
BCER98_RS18975	COG1294	oxidase, subunit
BCER98_RS18980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BCER98_RS18985	COG1620	l-lactate permease
BCER98_RS18990	COG2389	metal-binding protein
BCER98_RS19000	COG1368	sulfuric ester hydrolase activity
BCER98_RS19010	COG0791	NLP P60 protein
BCER98_RS19010	COG1388	LysM domain
BCER98_RS19015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BCER98_RS19025	COG1215	transferase activity, transferring glycosyl groups
BCER98_RS19030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BCER98_RS19035	COG3584	3D domain protein
BCER98_RS19035	COG1388	LysM domain
BCER98_RS19045	COG4715	Zinc finger, swim domain protein
BCER98_RS19050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCER98_RS19090	COG0577	efflux transmembrane transporter activity
BCER98_RS19095	COG1136	(ABC) transporter
BCER98_RS19130	COG3850	Histidine kinase
BCER98_RS19130	COG5002	protein histidine kinase activity
BCER98_RS19135	COG0745	RESPONSE REGULATOR receiver
BCER98_RS19145	COG1316	TRANSCRIPTIONal
BCER98_RS19150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BCER98_RS19160	COG1609	Transcriptional regulator
BCER98_RS19165	COG0739	heme binding
BCER98_RS19180	COG3279	Response regulator of the LytR AlgR family
BCER98_RS19185	COG2385	sporulation resulting in formation of a cellular spore
BCER98_RS19200	COG4836	Membrane
BCER98_RS19205	COG1007	ATP synthesis coupled electron transport
BCER98_RS19210	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCER98_RS19215	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCER98_RS19220	COG0713	ATP synthesis coupled electron transport
BCER98_RS19225	COG0839	Belongs to the complex I subunit 6 family
BCER98_RS19235	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BCER98_RS19240	COG0649	NAD binding
BCER98_RS19245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCER98_RS19250	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCER98_RS19255	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCER98_RS19265	COG5001	Diguanylate cyclase
BCER98_RS19265	COG3300	MHYT domain
BCER98_RS19280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCER98_RS19285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCER98_RS19290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCER98_RS19295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCER98_RS19300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCER98_RS19305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCER98_RS19310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCER98_RS19330	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCER98_RS19335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCER98_RS19345	COG0698	ribose 5-phosphate isomerase
BCER98_RS19365	COG2259	Doxx family
BCER98_RS19370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BCER98_RS19385	COG0009	L-threonylcarbamoyladenylate synthase
BCER98_RS19400	COG2890	protein-(glutamine-N5) methyltransferase activity
BCER98_RS19405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCER98_RS19410	COG1435	thymidine kinase activity
BCER98_RS19420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BCER98_RS19425	COG1494	fructose-1,6-bisphosphatase
BCER98_RS19445	COG4821	SIS domain
BCER98_RS19450	COG0504	CTP synthase activity
BCER98_RS19465	COG1960	acyl-CoA dehydrogenase activity
BCER98_RS19470	COG1960	acyl-CoA dehydrogenase activity
BCER98_RS19475	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCER98_RS19480	COG0183	Belongs to the thiolase family
BCER98_RS19485	COG2181	nitrate reductase activity
BCER98_RS19485	COG0247	lactate metabolic process
BCER98_RS19490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCER98_RS19505	COG2197	response regulator
BCER98_RS19510	COG4585	Histidine kinase
BCER98_RS19515	COG0842	Transport permease protein
BCER98_RS19520	COG1131	(ABC) transporter
BCER98_RS19525	COG0024	Methionine aminopeptidase
BCER98_RS19530	COG2234	aminopeptidase activity
BCER98_RS19545	COG4506	Protein conserved in bacteria
BCER98_RS19550	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCER98_RS19570	COG0010	Belongs to the arginase family
BCER98_RS19575	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BCER98_RS19580	COG2814	Major facilitator Superfamily
BCER98_RS19585	COG0789	Transcriptional regulator
BCER98_RS19590	COG0584	glycerophosphoryl diester phosphodiesterase
BCER98_RS19595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCER98_RS19605	COG1404	Belongs to the peptidase S8 family
BCER98_RS19625	COG1994	Peptidase M50
BCER98_RS19635	COG1078	dGTPase activity
BCER98_RS19640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BCER98_RS19645	COG1120	ATPase activity
BCER98_RS19650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS19655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCER98_RS19660	COG4844	belongs to the
BCER98_RS19675	COG0280	phosphate acetyltransferase
BCER98_RS19680	COG3253	May function as heme-dependent peroxidase
BCER98_RS19690	COG3773	Cell wall hydrolase
BCER98_RS19700	COG2363	Small membrane protein
BCER98_RS19710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BCER98_RS19715	COG2233	PERMEase
BCER98_RS19720	COG0561	phosphatase activity
BCER98_RS19725	COG2814	Major facilitator Superfamily
BCER98_RS19730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCER98_RS19735	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BCER98_RS19740	COG1131	(ABC) transporter
BCER98_RS19745	COG2755	lipolytic protein G-D-S-L family
BCER98_RS19750	COG0460	homoserine dehydrogenase
BCER98_RS19755	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BCER98_RS19760	COG2873	o-acetylhomoserine
BCER98_RS19770	COG0351	phosphomethylpyrimidine kinase
BCER98_RS19780	COG1966	Carbon starvation protein
BCER98_RS19785	COG3279	Response regulator of the LytR AlgR family
BCER98_RS19795	COG2801	Transposase and inactivated derivatives
BCER98_RS19800	COG0477	Major facilitator Superfamily
BCER98_RS19805	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BCER98_RS19810	COG0438	transferase activity, transferring glycosyl groups
BCER98_RS19825	COG0840	transmembrane signaling receptor activity
BCER98_RS19845	COG1607	acyl-coa hydrolase
BCER98_RS19850	COG1216	Glycosyl transferase, family 2
BCER98_RS19865	COG0463	Glycosyl transferase, family 2
BCER98_RS19880	COG0463	Glycosyl transferase, family 2
BCER98_RS19885	COG0488	(ABC) transporter
BCER98_RS19890	COG1309	transcriptional regulator
BCER98_RS19895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BCER98_RS19900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCER98_RS19900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCER98_RS19905	COG0628	permease
BCER98_RS19910	COG1346	cytolysis
BCER98_RS19920	COG3279	Response regulator of the LytR AlgR family
BCER98_RS19925	COG3275	phosphorelay sensor kinase activity
BCER98_RS19930	COG2814	Major facilitator Superfamily
BCER98_RS19935	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BCER98_RS19940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCER98_RS19955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCER98_RS19960	COG3711	transcriptional antiterminator
BCER98_RS19960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCER98_RS20060	COG0457	Tetratricopeptide repeat
BCER98_RS20110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BCER98_RS20115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BCER98_RS20125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCER98_RS20130	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BCER98_RS20135	COG4853	Protein conserved in bacteria
BCER98_RS20145	COG5002	protein histidine kinase activity
BCER98_RS20150	COG0745	RESPONSE REGULATOR receiver
BCER98_RS20175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCER98_RS20180	COG0305	Participates in initiation and elongation during chromosome replication
BCER98_RS20185	COG0359	binds to the 23S rRNA
BCER98_RS20190	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BCER98_RS20195	COG4241	membrane
BCER98_RS20200	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCER98_RS20210	COG0360	Binds together with S18 to 16S ribosomal RNA
BCER98_RS20215	COG0012	GTP binding
BCER98_RS20220	COG4481	Protein conserved in bacteria
BCER98_RS20225	COG0668	transmembrane transport
BCER98_RS20235	COG1475	DNA binding
BCER98_RS20240	COG1192	Involved in chromosome partitioning
BCER98_RS20245	COG1475	DNA binding
BCER98_RS20250	COG0357	Ribosomal RNA small subunit methyltransferase G
BCER98_RS20255	COG0445	tRNA wobble uridine modification
BCER98_RS20260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCER98_RS20265	COG1847	R3H domain protein
BCER98_RS20270	COG0706	membrane insertase activity
BCER98_RS20275	COG0594	ribonuclease P activity
BCER98_RS20280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCER98_RS20365	COG3681	Belongs to the UPF0597 family
BCER98_RS20390	COG2376	Dihydroxyacetone kinase
BCER98_RS20395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BCER98_RS20415	COG0457	Tetratricopeptide repeat
BCER98_RS20415	COG0463	Glycosyl transferase, family 2
BCER98_RS20430	COG0475	glutathione-regulated potassium exporter activity
BCER98_RS20435	COG0475	glutathione-regulated potassium exporter activity
BCER98_RS20450	COG3328	transposase activity
BCER98_RS20455	COG3328	transposase activity
BCER98_RS20475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCER98_RS20480	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family