locus-tag	class	description
BC359_RS00040	COG0726	polysaccharide deacetylase
BC359_RS00045	COG2194	sulfuric ester hydrolase activity
BC359_RS00055	COG0489	protein tyrosine kinase activity
BC359_RS00060	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS00080	COG3341	Caulimovirus viroplasmin
BC359_RS00080	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_RS00085	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC359_RS00090	COG0732	type I restriction modification DNA specificity domain
BC359_RS00095	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BC359_RS00130	COG0582	viral genome integration into host DNA
BC359_RS00140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BC359_RS00145	COG0101	tRNA pseudouridine synthase activity
BC359_RS00150	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BC359_RS00155	COG1122	ATPase activity
BC359_RS00160	COG1122	ATPase activity
BC359_RS00165	COG0203	ribosomal protein L17
BC359_RS00170	COG0202	RNA polymerase activity
BC359_RS00175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BC359_RS00180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BC359_RS00185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC359_RS00190	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BC359_RS00195	COG0024	Methionine aminopeptidase
BC359_RS00200	COG0563	adenylate kinase activity
BC359_RS00205	COG0201	protein transport
BC359_RS00210	COG0200	Binds to the 23S rRNA
BC359_RS00215	COG1841	ribosomal large subunit assembly
BC359_RS00220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BC359_RS00240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC359_RS00250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BC359_RS00255	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BC359_RS00260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BC359_RS00270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BC359_RS00275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BC359_RS00280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BC359_RS00290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BC359_RS00295	COG0089	rRNA binding
BC359_RS00300	COG0088	Forms part of the polypeptide exit tunnel
BC359_RS00305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BC359_RS00315	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BC359_RS00325	COG0049	tRNA binding
BC359_RS00330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BC359_RS00335	COG1358	cellular component organization or biogenesis
BC359_RS00345	COG0085	RNA polymerase activity
BC359_RS00350	COG2813	Specifically methylates the guanine in position
BC359_RS00355	COG0222	ribosome binding
BC359_RS00360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BC359_RS00365	COG0081	regulation of translation
BC359_RS00370	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BC359_RS00375	COG0250	Participates in transcription elongation, termination and antitermination
BC359_RS00380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC359_RS00385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC359_RS00395	COG3688	RNA-binding protein containing a PIN domain
BC359_RS00410	COG0215	cysteine-tRNA ligase activity
BC359_RS00415	COG1045	serine acetyltransferase
BC359_RS00420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BC359_RS00425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BC359_RS00430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BC359_RS00435	COG4956	integral membrane protein (PIN domain superfamily)
BC359_RS00440	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BC359_RS00445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BC359_RS00450	COG0542	response to heat
BC359_RS00455	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BC359_RS00460	COG3880	PFAM UvrB UvrC protein
BC359_RS00485	COG1523	belongs to the glycosyl hydrolase 13 family
BC359_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BC359_RS00495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC359_RS00500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC359_RS00505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC359_RS00510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC359_RS00515	COG0512	Glutamine amidotransferase of anthranilate synthase
BC359_RS00520	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BC359_RS00525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_RS00530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BC359_RS00535	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BC359_RS00540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC359_RS00545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BC359_RS00555	COG0515	serine threonine protein kinase
BC359_RS00560	COG2304	oxidoreductase activity
BC359_RS00580	COG1098	S1 RNA binding domain
BC359_RS00585	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BC359_RS00600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BC359_RS00605	COG3956	TIGRFAM MazG family protein
BC359_RS00610	COG2244	polysaccharide biosynthetic process
BC359_RS00615	COG2002	toxin-antitoxin pair type II binding
BC359_RS00620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BC359_RS00635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BC359_RS00645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BC359_RS00650	COG2088	sporulation resulting in formation of a cellular spore
BC359_RS00660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC359_RS00675	COG4466	Protein conserved in bacteria
BC359_RS00685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC359_RS00695	COG0084	hydrolase, TatD family'
BC359_RS00705	COG2002	toxin-antitoxin pair type II binding
BC359_RS00710	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BC359_RS00720	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BC359_RS00725	COG4467	Involved in initiation control of chromosome replication
BC359_RS00730	COG1774	PSP1 C-terminal conserved region
BC359_RS00735	COG0470	DNA polymerase III
BC359_RS00740	COG3870	Protein conserved in bacteria
BC359_RS00745	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BC359_RS00750	COG1982	Orn Lys Arg decarboxylase major
BC359_RS00855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BC359_RS00860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BC359_RS00865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC359_RS00875	COG0590	tRNA wobble adenosine to inosine editing
BC359_RS00880	COG1335	isochorismatase
BC359_RS00885	COG1388	LysM domain
BC359_RS00885	COG3858	chitin binding
BC359_RS00890	COG1428	Deoxynucleoside kinase
BC359_RS00895	COG1428	Deoxynucleoside kinase
BC359_RS00910	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BC359_RS00925	COG0516	GMP reductase activity
BC359_RS00925	COG0517	IMP dehydrogenase activity
BC359_RS00960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC359_RS00970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BC359_RS00975	COG2501	S4 domain
BC359_RS00980	COG0592	DNA-directed DNA polymerase activity
BC359_RS00985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BC359_RS00995	COG0594	ribonuclease P activity
BC359_RS01000	COG0706	membrane insertase activity
BC359_RS01005	COG1847	R3H domain protein
BC359_RS01010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BC359_RS01015	COG0445	tRNA wobble uridine modification
BC359_RS01025	COG1475	DNA binding
BC359_RS01030	COG1192	Involved in chromosome partitioning
BC359_RS01035	COG1475	DNA binding
BC359_RS01045	COG3949	Membrane
BC359_RS01050	COG0668	transmembrane transport
BC359_RS01055	COG4481	Protein conserved in bacteria
BC359_RS01060	COG0012	GTP binding
BC359_RS01065	COG0360	Binds together with S18 to 16S ribosomal RNA
BC359_RS01075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BC359_RS01085	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BC359_RS01095	COG0305	Participates in initiation and elongation during chromosome replication
BC359_RS01100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BC359_RS01135	COG0745	RESPONSE REGULATOR receiver
BC359_RS01140	COG5002	protein histidine kinase activity
BC359_RS01145	COG4863	YycH protein
BC359_RS01150	COG4853	Protein conserved in bacteria
BC359_RS01155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BC359_RS01160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC359_RS01175	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_RS01195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_RS01205	COG0732	type I restriction modification DNA specificity domain
BC359_RS01345	COG0210	DNA helicase
BC359_RS01385	COG3645	SOS response
BC359_RS01390	COG0732	type I restriction modification DNA specificity domain
BC359_RS01395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC359_RS01420	COG1401	restriction endodeoxyribonuclease activity
BC359_RS01475	COG2814	Major facilitator Superfamily
BC359_RS01480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC359_RS01495	COG1464	Belongs to the NlpA lipoprotein family
BC359_RS01505	COG3634	alkyl hydroperoxide reductase activity
BC359_RS01510	COG0450	alkyl hydroperoxide reductase
BC359_RS01515	COG2972	Histidine kinase
BC359_RS01520	COG3279	Response regulator of the LytR AlgR family
BC359_RS01525	COG2182	Extracellular solute-binding protein
BC359_RS01530	COG1621	beta-fructofuranosidase activity
BC359_RS01535	COG1621	beta-fructofuranosidase activity
BC359_RS01555	COG2966	Psort location CytoplasmicMembrane, score
BC359_RS01560	COG3610	response to peptide
BC359_RS01565	COG1368	sulfuric ester hydrolase activity
BC359_RS01575	COG0728	peptidoglycan biosynthetic process
BC359_RS01600	COG0438	transferase activity, transferring glycosyl groups
BC359_RS01610	COG1263	PTS System
BC359_RS01610	COG2190	(PTS) system
BC359_RS01610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS01615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC359_RS01620	COG0561	phosphatase activity
BC359_RS01625	COG0351	phosphomethylpyrimidine kinase
BC359_RS01630	COG0686	Belongs to the AlaDH PNT family
BC359_RS01635	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BC359_RS01635	COG2508	Transcriptional regulator
BC359_RS01640	COG1115	amino acid carrier protein
BC359_RS01645	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BC359_RS01650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC359_RS01660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BC359_RS01670	COG2363	Small membrane protein
BC359_RS01680	COG3773	Cell wall hydrolase
BC359_RS01690	COG0280	phosphate acetyltransferase
BC359_RS01695	COG0095	Lipoate-protein ligase
BC359_RS01710	COG1078	dGTPase activity
BC359_RS01715	COG3465	dGTPase activity
BC359_RS01725	COG1994	Peptidase M50
BC359_RS01735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_RS01740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BC359_RS01745	COG0010	Belongs to the arginase family
BC359_RS01765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_RS01770	COG2181	nitrate reductase activity
BC359_RS01770	COG0247	lactate metabolic process
BC359_RS01780	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC359_RS01785	COG1960	acyl-CoA dehydrogenase activity
BC359_RS01790	COG1960	acyl-CoA dehydrogenase activity
BC359_RS01800	COG1703	isobutyryl-CoA mutase activity
BC359_RS01800	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_RS01800	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_RS01805	COG3343	RNA polymerase activity
BC359_RS01810	COG0504	CTP synthase activity
BC359_RS01815	COG4821	SIS domain
BC359_RS01820	COG2204	response regulator
BC359_RS01825	COG0191	fructose-bisphosphate aldolase activity
BC359_RS01830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BC359_RS01840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC359_RS01850	COG1435	thymidine kinase activity
BC359_RS01860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BC359_RS01865	COG2890	protein-(glutamine-N5) methyltransferase activity
BC359_RS01885	COG1971	Probably functions as a manganese efflux pump
BC359_RS01895	COG0698	ribose 5-phosphate isomerase
BC359_RS01910	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BC359_RS01915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BC359_RS01935	COG0356	it plays a direct role in the translocation of protons across the membrane
BC359_RS01940	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC359_RS01945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BC359_RS01950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BC359_RS01955	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BC359_RS01960	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BC359_RS01965	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BC359_RS01970	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BC359_RS01975	COG4836	Membrane
BC359_RS01995	COG2385	sporulation resulting in formation of a cellular spore
BC359_RS02000	COG0739	heme binding
BC359_RS02005	COG1609	Transcriptional regulator
BC359_RS02015	COG4786	Flagellar basal body rod
BC359_RS02020	COG4786	Flagellar basal body rod
BC359_RS02045	COG0629	single-stranded DNA binding
BC359_RS02050	COG0791	NLP P60 protein
BC359_RS02050	COG1388	LysM domain
BC359_RS02055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC359_RS02065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC359_RS02075	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BC359_RS02080	COG2268	Band 7 protein
BC359_RS02085	COG1585	Membrane protein implicated in regulation of membrane protease activity
BC359_RS02090	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC359_RS02095	COG1316	TRANSCRIPTIONal
BC359_RS02100	COG1739	Uncharacterized protein family UPF0029
BC359_RS02105	COG4585	Histidine kinase
BC359_RS02110	COG2197	response regulator
BC359_RS02130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_RS02135	COG1728	Protein conserved in bacteria
BC359_RS02140	COG1307	EDD domain protein, DegV family
BC359_RS02145	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BC359_RS02150	COG1040	competence protein
BC359_RS02160	COG2747	anti-sigma28 factor FlgM
BC359_RS02170	COG4786	Flagellar basal body rod
BC359_RS02170	COG1256	bacterial-type flagellum assembly
BC359_RS02175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_RS02185	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BC359_RS02190	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BC359_RS02195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_RS02200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC359_RS02225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BC359_RS02230	COG1516	flagellar protein fliS
BC359_RS02240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC359_RS02245	COG0653	protein targeting
BC359_RS02250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC359_RS02260	COG2010	Cytochrome c
BC359_RS02265	COG2884	Cell division ATP-binding protein ftsE
BC359_RS02270	COG2177	Part of the ABC transporter FtsEX involved in
BC359_RS02275	COG0739	heme binding
BC359_RS02280	COG0793	Belongs to the peptidase S41A family
BC359_RS02280	COG3409	Peptidoglycan-binding domain 1 protein
BC359_RS02285	COG1733	regulation of RNA biosynthetic process
BC359_RS02290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BC359_RS02300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC359_RS02305	COG0506	proline dehydrogenase activity
BC359_RS02310	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS02315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_RS02330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC359_RS02335	COG3595	metallopeptidase activity
BC359_RS02340	COG1983	PspC domain protein
BC359_RS02345	COG1950	PFAM Membrane protein of
BC359_RS02350	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BC359_RS02355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BC359_RS02360	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC359_RS02365	COG0546	phosphoglycolate phosphatase activity
BC359_RS02370	COG0110	maltose O-acetyltransferase activity
BC359_RS02375	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BC359_RS02380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BC359_RS02385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BC359_RS02390	COG0131	Imidazoleglycerol-phosphate dehydratase
BC359_RS02395	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BC359_RS02400	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BC359_RS02405	COG0107	imidazoleglycerol-phosphate synthase activity
BC359_RS02410	COG0140	phosphoribosyl-ATP diphosphatase activity
BC359_RS02410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BC359_RS02415	COG0457	Tetratricopeptide repeat
BC359_RS02420	COG0492	ferredoxin-NADP+ reductase activity
BC359_RS02425	COG1051	belongs to the nudix hydrolase family
BC359_RS02430	COG1660	Displays ATPase and GTPase activities
BC359_RS02435	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC359_RS02440	COG1481	regulation of sporulation
BC359_RS02445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC359_RS02465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC359_RS02505	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC359_RS02510	COG1647	Serine aminopeptidase, S33
BC359_RS02515	COG0557	exoribonuclease II activity
BC359_RS02520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BC359_RS02540	COG0477	Major facilitator Superfamily
BC359_RS02550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC359_RS02555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_RS02560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_RS02565	COG1120	ATPase activity
BC359_RS02590	COG1024	Enoyl-CoA hydratase
BC359_RS02590	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC359_RS02595	COG0183	Belongs to the thiolase family
BC359_RS02600	COG1960	acyl-CoA dehydrogenase activity
BC359_RS02605	COG1393	Belongs to the ArsC family
BC359_RS02610	COG0509	glycine decarboxylation via glycine cleavage system
BC359_RS02620	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BC359_RS02630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BC359_RS02635	COG2011	ABC-type metal ion transport system permease component
BC359_RS02640	COG1464	Belongs to the NlpA lipoprotein family
BC359_RS02645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC359_RS02650	COG0396	ATPase activity
BC359_RS02655	COG0719	Fe-S assembly protein
BC359_RS02660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC359_RS02665	COG0822	iron-sulfur transferase activity
BC359_RS02670	COG0719	Fe-S assembly protein
BC359_RS02675	COG1801	Protein of unknown function DUF72
BC359_RS02680	COG3377	Domain of unknown function (DUF1805)
BC359_RS02695	COG1757	Na H antiporter
BC359_RS02700	COG0733	neurotransmitter:sodium symporter activity
BC359_RS02715	COG0739	heme binding
BC359_RS02720	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BC359_RS02730	COG4470	Protein conserved in bacteria
BC359_RS02740	COG2445	Protein of unknown function DUF86
BC359_RS02745	COG0647	UMP catabolic process
BC359_RS02750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC359_RS02755	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC359_RS02760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC359_RS02765	COG0460	homoserine dehydrogenase
BC359_RS02770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BC359_RS02775	COG0083	homoserine kinase activity
BC359_RS02780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BC359_RS02785	COG4837	Protein of unknown function (DUF1462)
BC359_RS02790	COG1252	NADH dehydrogenase
BC359_RS02795	COG4844	belongs to the
BC359_RS02805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BC359_RS02810	COG0316	Belongs to the HesB IscA family
BC359_RS02815	COG4974	Belongs to the 'phage' integrase family
BC359_RS02900	COG0316	Belongs to the HesB IscA family
BC359_RS02910	COG0492	ferredoxin-NADP+ reductase activity
BC359_RS02915	COG1252	NADH dehydrogenase
BC359_RS02925	COG3584	3D domain protein
BC359_RS02930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BC359_RS02935	COG2056	Na+-H+ antiporter family
BC359_RS02950	COG2050	protein possibly involved in aromatic compounds catabolism
BC359_RS02955	COG5018	Exonuclease
BC359_RS02970	COG2032	superoxide dismutase activity
BC359_RS02975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BC359_RS02980	COG2267	carboxylic ester hydrolase activity
BC359_RS02985	COG1522	sequence-specific DNA binding
BC359_RS02990	COG0436	Aminotransferase
BC359_RS02995	COG1098	S1 RNA binding domain
BC359_RS03000	COG2155	Conserved Protein
BC359_RS03005	COG1979	alcohol dehydrogenase
BC359_RS03010	COG1320	monovalent cation:proton antiporter activity
BC359_RS03015	COG2212	antiporter activity
BC359_RS03020	COG1863	multisubunit Na H antiporter MnhE subunit
BC359_RS03025	COG0651	ATP synthesis coupled electron transport
BC359_RS03030	COG1006	Multisubunit Na H antiporter MnhC subunit
BC359_RS03035	COG2111	Na H antiporter
BC359_RS03040	COG2111	Na H antiporter
BC359_RS03040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC359_RS03050	COG0166	Belongs to the GPI family
BC359_RS03060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BC359_RS03065	COG0346	lactoylglutathione lyase activity
BC359_RS03075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC359_RS03090	COG0306	phosphate transporter
BC359_RS03100	COG0529	Catalyzes the synthesis of activated sulfate
BC359_RS03120	COG1285	pathogenesis
BC359_RS03125	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_RS03255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BC359_RS03260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BC359_RS03265	COG0297	glycogen (starch) synthase activity
BC359_RS03270	COG0058	SHG alpha-glucan phosphorylase activity
BC359_RS03275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC359_RS03280	COG1169	isochorismate synthase
BC359_RS03285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BC359_RS03290	COG0596	Alpha beta hydrolase
BC359_RS03295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC359_RS03300	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_RS03305	COG4948	Mandelate Racemase Muconate Lactonizing
BC359_RS03310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC359_RS03315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC359_RS03340	COG1294	oxidase, subunit
BC359_RS03345	COG1271	oxidase subunit
BC359_RS03350	COG0254	rRNA binding
BC359_RS03355	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC359_RS03360	COG0523	cobalamin synthesis protein
BC359_RS03365	COG0288	reversible hydration of carbon dioxide
BC359_RS03370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BC359_RS03375	COG1854	S-ribosylhomocysteine lyase activity
BC359_RS03385	COG0783	Belongs to the Dps family
BC359_RS03390	COG4824	toxin secretion phage lysis holin
BC359_RS03400	COG0494	nUDIX hydrolase
BC359_RS03405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC359_RS03410	COG1116	anion transmembrane transporter activity
BC359_RS03415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC359_RS03420	COG1506	peptidase
BC359_RS03430	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BC359_RS03435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BC359_RS03440	COG0438	transferase activity, transferring glycosyl groups
BC359_RS03440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC359_RS03450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BC359_RS03455	COG2267	carboxylic ester hydrolase activity
BC359_RS03465	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BC359_RS03470	COG1242	4 iron, 4 sulfur cluster binding
BC359_RS03485	COG2814	Major facilitator Superfamily
BC359_RS03490	COG2610	gluconate transmembrane transporter activity
BC359_RS03495	COG0495	leucyl-tRNA aminoacylation
BC359_RS03500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_RS03510	COG2081	HI0933 family
BC359_RS03515	COG2244	polysaccharide biosynthetic process
BC359_RS03520	COG1187	pseudouridine synthase activity
BC359_RS03525	COG1349	DNA-binding transcription factor activity
BC359_RS03530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC359_RS03535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_RS03545	COG1523	belongs to the glycosyl hydrolase 13 family
BC359_RS03550	COG0510	thiamine kinase activity
BC359_RS03560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BC359_RS03565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_RS03575	COG1363	Peptidase, m42
BC359_RS03580	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BC359_RS03585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_RS03590	COG4848	Belongs to the UPF0354 family
BC359_RS03595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC359_RS03600	COG1674	ftsk spoiiie
BC359_RS03610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BC359_RS03625	COG4980	gas vesicle protein
BC359_RS03630	COG3118	belongs to the thioredoxin family
BC359_RS03635	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC359_RS03635	COG1605	Chorismate mutase
BC359_RS03655	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC359_RS03660	COG0517	IMP dehydrogenase activity
BC359_RS03665	COG0454	-acetyltransferase
BC359_RS03670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC359_RS03690	COG2203	Gaf domain
BC359_RS03690	COG2199	diguanylate cyclase activity
BC359_RS03695	COG1956	GAF domain-containing protein
BC359_RS03700	COG1309	transcriptional regulator
BC359_RS03705	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC359_RS03710	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BC359_RS03715	COG1114	Component of the transport system for branched-chain amino acids
BC359_RS03720	COG1104	cysteine desulfurase activity
BC359_RS03725	COG0301	tRNA thio-modification
BC359_RS03735	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BC359_RS03740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BC359_RS03745	COG0616	signal peptide processing
BC359_RS03750	COG1714	RDD family
BC359_RS03760	COG3874	Sporulation protein YtfJ
BC359_RS03765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BC359_RS03770	COG0827	DNA restriction-modification system
BC359_RS03775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BC359_RS03790	COG0137	argininosuccinate synthase activity
BC359_RS03795	COG0165	Argininosuccinate lyase
BC359_RS03805	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BC359_RS03815	COG4109	DRTGG domain
BC359_RS03830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC359_RS03845	COG0587	DNA-directed DNA polymerase activity
BC359_RS03855	COG1725	Transcriptional regulator
BC359_RS03860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BC359_RS03865	COG0825	malonyl-CoA metabolic process
BC359_RS03875	COG3030	protein affecting phage T7 exclusion by the F plasmid
BC359_RS03880	COG0628	permease
BC359_RS03885	COG2707	UPF0756 membrane protein
BC359_RS03890	COG0372	Belongs to the citrate synthase family
BC359_RS03895	COG0538	isocitrate dehydrogenase activity
BC359_RS03900	COG0039	L-malate dehydrogenase activity
BC359_RS03910	COG0745	RESPONSE REGULATOR receiver
BC359_RS03915	COG5002	protein histidine kinase activity
BC359_RS03920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC359_RS03920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC359_RS03925	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BC359_RS03930	COG1971	Probably functions as a manganese efflux pump
BC359_RS03935	COG0237	dephospho-CoA kinase activity
BC359_RS03940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC359_RS03955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BC359_RS03960	COG3611	Membrane attachment protein
BC359_RS03965	COG1484	DNA-dependent DNA replication
BC359_RS03975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC359_RS03980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BC359_RS03985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BC359_RS03990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BC359_RS03995	COG3326	Membrane
BC359_RS04015	COG1363	Peptidase, m42
BC359_RS04025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC359_RS04030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BC359_RS04040	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC359_RS04045	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BC359_RS04050	COG1286	toxin biosynthetic process
BC359_RS04055	COG1796	DNA polymerase
BC359_RS04055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC359_RS04060	COG1193	negative regulation of DNA recombination
BC359_RS04065	COG3766	membrane
BC359_RS04070	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_RS04075	COG1309	transcriptional regulator
BC359_RS04080	COG1024	Enoyl-CoA hydratase
BC359_RS04085	COG2086	electron transfer activity
BC359_RS04090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BC359_RS04095	COG3118	belongs to the thioredoxin family
BC359_RS04100	COG0322	excinuclease ABC activity
BC359_RS04105	COG0527	aspartate kinase activity
BC359_RS04110	COG1719	4-vinyl reductase, 4VR
BC359_RS04115	COG2009	succinate dehydrogenase
BC359_RS04120	COG1053	succinate dehydrogenase
BC359_RS04130	COG2197	response regulator
BC359_RS04140	COG0490	domain, Protein
BC359_RS04145	COG0475	glutathione-regulated potassium exporter activity
BC359_RS04160	COG1392	Phosphate transport regulator
BC359_RS04165	COG0306	phosphate transporter
BC359_RS04170	COG1846	Transcriptional regulator
BC359_RS04180	COG5401	PFAM Sporulation and spore germination
BC359_RS04185	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BC359_RS04195	COG0622	Phosphoesterase
BC359_RS04205	COG0028	Belongs to the TPP enzyme family
BC359_RS04210	COG0440	acetolactate synthase activity
BC359_RS04215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BC359_RS04220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC359_RS04230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BC359_RS04235	COG0066	3-isopropylmalate dehydratase activity
BC359_RS04240	COG0457	Tetratricopeptide repeat
BC359_RS04240	COG1477	protein flavinylation
BC359_RS04245	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC359_RS04250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BC359_RS04255	COG1067	ATP-dependent peptidase activity
BC359_RS04255	COG0470	DNA polymerase III
BC359_RS04265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BC359_RS04280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC359_RS04285	COG0181	hydroxymethylbilane synthase activity
BC359_RS04295	COG0113	porphobilinogen synthase activity
BC359_RS04305	COG1388	LysM domain
BC359_RS04320	COG0525	valine-tRNA ligase activity
BC359_RS04330	COG0285	dihydrofolate synthase activity
BC359_RS04340	COG2322	membrane
BC359_RS04350	COG1459	type II secretion system
BC359_RS04360	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BC359_RS04395	COG2003	Belongs to the UPF0758 family
BC359_RS04400	COG1077	Cell shape determining protein MreB Mrl
BC359_RS04405	COG1792	Involved in formation and maintenance of cell shape
BC359_RS04410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BC359_RS04420	COG2894	cell division
BC359_RS04425	COG0739	heme binding
BC359_RS04430	COG1994	Peptidase M50
BC359_RS04435	COG1530	ribonuclease E activity
BC359_RS04445	COG2868	ribosomal protein
BC359_RS04450	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BC359_RS04455	COG3290	protein histidine kinase activity
BC359_RS04465	COG4492	Belongs to the UPF0735 family
BC359_RS04470	COG0077	Prephenate dehydratase
BC359_RS04475	COG1827	regulation of RNA biosynthetic process
BC359_RS04480	COG1104	cysteine desulfurase activity
BC359_RS04490	COG0157	Belongs to the NadC ModD family
BC359_RS04500	COG1388	LysM domain
BC359_RS04520	COG0632	four-way junction helicase activity
BC359_RS04535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BC359_RS04540	COG0343	queuine tRNA-ribosyltransferase activity
BC359_RS04545	COG1862	Preprotein translocase
BC359_RS04555	COG2323	membrane
BC359_RS04560	COG2244	polysaccharide biosynthetic process
BC359_RS04570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC359_RS04570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC359_RS04575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC359_RS04585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC359_RS04590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC359_RS04600	COG4991	sh3 domain protein
BC359_RS04600	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS04600	COG3103	Sh3 type 3 domain protein
BC359_RS04610	COG0124	histidyl-tRNA synthetase
BC359_RS04615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BC359_RS04625	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BC359_RS04630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC359_RS04635	COG1959	2 iron, 2 sulfur cluster binding
BC359_RS04640	COG1104	cysteine desulfurase activity
BC359_RS04645	COG0482	sulfurtransferase activity
BC359_RS04655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC359_RS04670	COG0628	permease
BC359_RS04675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC359_RS04680	COG4472	Bacterial protein of unknown function (DUF965)
BC359_RS04690	COG3906	Belongs to the UPF0473 family
BC359_RS04695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BC359_RS04700	COG4122	O-methyltransferase activity
BC359_RS04705	COG0826	peptidase U32
BC359_RS04710	COG0826	peptidase U32
BC359_RS04715	COG0572	uridine kinase
BC359_RS04720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BC359_RS04725	COG0768	penicillin binding
BC359_RS04740	COG2226	methyltransferase
BC359_RS04745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC359_RS04750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_RS04755	COG0626	cystathionine gamma-synthase activity
BC359_RS04780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BC359_RS04785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BC359_RS04795	COG1534	Rna-binding protein
BC359_RS04800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BC359_RS04805	COG1713	HD superfamily hydrolase involved in NAD metabolism
BC359_RS04810	COG0799	negative regulation of ribosome biogenesis
BC359_RS04815	COG2226	methyltransferase
BC359_RS04820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_RS04825	COG1555	photosystem II stabilization
BC359_RS04825	COG1596	polysaccharide export
BC359_RS04830	COG2131	deaminase
BC359_RS04835	COG0658	competence protein
BC359_RS04835	COG2333	competence protein COMEC
BC359_RS04845	COG1466	dna polymerase III delta subunit
BC359_RS04850	COG0268	Binds directly to 16S ribosomal RNA
BC359_RS04855	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BC359_RS04865	COG0481	GTPase activity
BC359_RS04870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC359_RS04880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BC359_RS04885	COG0443	Heat shock 70 kDa protein
BC359_RS04890	COG0484	heat shock protein binding
BC359_RS04895	COG2264	protein methyltransferase activity
BC359_RS04900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BC359_RS04905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC359_RS04915	COG1610	YqeY-like protein
BC359_RS04920	COG1030	water channel activity
BC359_RS04945	COG1702	phosphate starvation-inducible protein PhoH
BC359_RS04950	COG1480	7TM receptor with intracellular HD hydrolase
BC359_RS04960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BC359_RS04965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC359_RS04975	COG1381	Involved in DNA repair and RecF pathway recombination
BC359_RS04980	COG0517	IMP dehydrogenase activity
BC359_RS04985	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BC359_RS04990	COG1671	Belongs to the UPF0178 family
BC359_RS04995	COG0358	DNA primase activity
BC359_RS05000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC359_RS05005	COG1960	acyl-CoA dehydrogenase activity
BC359_RS05015	COG2384	SAM-dependent methyltransferase
BC359_RS05020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC359_RS05025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BC359_RS05040	COG0513	Belongs to the DEAD box helicase family
BC359_RS05055	COG1121	(ABC) transporter
BC359_RS05060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC359_RS05065	COG0735	belongs to the Fur family
BC359_RS05070	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BC359_RS05075	COG4709	membrane
BC359_RS05080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BC359_RS05090	COG2814	Major facilitator Superfamily
BC359_RS05110	COG2839	Protein conserved in bacteria
BC359_RS05145	COG0477	Major facilitator Superfamily
BC359_RS05150	COG0768	penicillin binding
BC359_RS05155	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC359_RS05160	COG0573	inorganic phosphate transmembrane transporter activity
BC359_RS05165	COG0581	inorganic phosphate transmembrane transporter activity
BC359_RS05175	COG0704	Plays a role in the regulation of phosphate uptake
BC359_RS05200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC359_RS05210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC359_RS05220	COG0705	Rhomboid family
BC359_RS05220	COG0457	Tetratricopeptide repeat
BC359_RS05225	COG4483	Protein conserved in bacteria
BC359_RS05230	COG1940	carbohydrate kinase activity
BC359_RS05235	COG1368	sulfuric ester hydrolase activity
BC359_RS05250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_RS05260	COG1393	Belongs to the ArsC family
BC359_RS05265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BC359_RS05270	COG1459	type II secretion system
BC359_RS05275	COG4537	Required for transformation and DNA binding
BC359_RS05280	COG4970	Tfp pilus assembly protein FimT
BC359_RS05315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC359_RS05320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BC359_RS05330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BC359_RS05335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_RS05340	COG0095	Lipoate-protein ligase
BC359_RS05345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC359_RS05350	COG1321	iron dependent repressor
BC359_RS05360	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC359_RS05370	COG3872	metal-dependent enzyme
BC359_RS05380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BC359_RS05385	COG0006	proline dipeptidase activity
BC359_RS05390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BC359_RS05400	COG3854	ATPases associated with a variety of cellular activities
BC359_RS05440	COG0511	ligase activity, forming carbon-carbon bonds
BC359_RS05445	COG0439	Biotin carboxylase
BC359_RS05450	COG1302	Protein conserved in bacteria
BC359_RS05455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC359_RS05465	COG1722	exodeoxyribonuclease VII activity
BC359_RS05470	COG0142	geranyltranstransferase activity
BC359_RS05480	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BC359_RS05490	COG0497	DNA recombination
BC359_RS05495	COG0750	zinc metalloprotease
BC359_RS05500	COG0745	RESPONSE REGULATOR receiver
BC359_RS05510	COG1620	l-lactate permease
BC359_RS05515	COG0039	L-malate dehydrogenase activity
BC359_RS05520	COG3093	addiction module antidote protein HigA
BC359_RS05525	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_RS05535	COG3829	transcription factor binding
BC359_RS05535	COG3290	protein histidine kinase activity
BC359_RS05560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC359_RS05565	COG0022	dehydrogenase e1 component
BC359_RS05570	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC359_RS05575	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_RS05575	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_RS05580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_RS05580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BC359_RS05595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC359_RS05600	COG0765	amino acid transport
BC359_RS05605	COG1126	abc transporter atp-binding protein
BC359_RS05610	COG4129	membrane
BC359_RS05615	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_RS05620	COG0346	lactoylglutathione lyase activity
BC359_RS05625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC359_RS05630	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC359_RS05635	COG0493	'glutamate synthase
BC359_RS05665	COG2508	Transcriptional regulator
BC359_RS05670	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS05675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC359_RS05685	COG1902	pentaerythritol trinitrate reductase activity
BC359_RS05690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_RS05695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_RS05700	COG0300	oxidoreductase activity
BC359_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS05715	COG4918	Iron-sulphur cluster biosynthesis
BC359_RS05720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC359_RS05730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BC359_RS05735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC359_RS05745	COG0667	Aldo Keto reductase
BC359_RS05755	COG0494	nUDIX hydrolase
BC359_RS05760	COG1300	Membrane
BC359_RS05765	COG0735	belongs to the Fur family
BC359_RS05780	COG4974	Belongs to the 'phage' integrase family
BC359_RS05800	COG1686	Belongs to the peptidase S11 family
BC359_RS05835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC359_RS05850	COG0697	spore germination
BC359_RS05860	COG4086	secreted protein
BC359_RS05865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC359_RS05875	COG1547	Domain of unknown function (DUF309)
BC359_RS05890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BC359_RS05895	COG1686	Belongs to the peptidase S11 family
BC359_RS05900	COG2715	membrane protein required for spore maturation
BC359_RS05905	COG0700	Nucleoside recognition
BC359_RS05915	COG0700	Nucleoside recognition
BC359_RS05920	COG1187	pseudouridine synthase activity
BC359_RS05925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_RS05930	COG1333	cytochrome c biogenesis protein
BC359_RS05935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC359_RS05940	COG0745	RESPONSE REGULATOR receiver
BC359_RS05945	COG5002	protein histidine kinase activity
BC359_RS05950	COG0739	heme binding
BC359_RS05955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC359_RS05960	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BC359_RS05975	COG0514	ATP-dependent DNA helicase (RecQ)
BC359_RS05990	COG1408	metallophosphoesterase
BC359_RS05995	COG0789	Transcriptional regulator
BC359_RS06005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC359_RS06010	COG0492	ferredoxin-NADP+ reductase activity
BC359_RS06015	COG0252	asparaginase activity
BC359_RS06020	COG2339	peptidase activity
BC359_RS06025	COG3409	Peptidoglycan-binding domain 1 protein
BC359_RS06025	COG3773	Cell wall hydrolase
BC359_RS06040	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BC359_RS06050	COG0539	negative regulation of cytoplasmic translation
BC359_RS06060	COG2271	Major facilitator Superfamily
BC359_RS06095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC359_RS06100	COG0776	regulation of translation
BC359_RS06105	COG0302	gtp cyclohydrolase
BC359_RS06115	COG0142	geranyltranstransferase activity
BC359_RS06120	COG2226	methyltransferase
BC359_RS06125	COG0142	geranyltranstransferase activity
BC359_RS06130	COG0105	UTP biosynthetic process
BC359_RS06135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC359_RS06140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BC359_RS06145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BC359_RS06155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC359_RS06160	COG0134	indole-3-glycerol-phosphate synthase activity
BC359_RS06165	COG0135	phosphoribosylanthranilate isomerase activity
BC359_RS06170	COG0133	tryptophan synthase activity
BC359_RS06175	COG0159	tryptophan synthase activity
BC359_RS06180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC359_RS06185	COG0287	Prephenate dehydrogenase
BC359_RS06190	COG0457	Tetratricopeptide repeat
BC359_RS06195	COG5582	Belongs to the UPF0302 family
BC359_RS06210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC359_RS06220	COG4347	Protein of unknown function (DUF1405)
BC359_RS06240	COG3679	Belongs to the UPF0342 family
BC359_RS06260	COG0742	ribosomal rna small subunit methyltransferase
BC359_RS06265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BC359_RS06270	COG3314	Sporulation integral membrane protein YlbJ
BC359_RS06275	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC359_RS06280	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC359_RS06285	COG1323	Belongs to the UPF0348 family
BC359_RS06290	COG1399	metal-binding, possibly nucleic acid-binding protein
BC359_RS06295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BC359_RS06300	COG1024	Enoyl-CoA hydratase
BC359_RS06310	COG0454	-acetyltransferase
BC359_RS06315	COG0439	Biotin carboxylase
BC359_RS06320	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC359_RS06325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC359_RS06330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC359_RS06340	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BC359_RS06350	COG4839	cell division protein FtsL
BC359_RS06370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC359_RS06375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BC359_RS06380	COG0772	Belongs to the SEDS family
BC359_RS06385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BC359_RS06390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BC359_RS06395	COG0849	cell division
BC359_RS06400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC359_RS06410	COG1191	sigma factor activity
BC359_RS06415	COG1191	sigma factor activity
BC359_RS06420	COG1873	PFAM PRC-barrel domain
BC359_RS06425	COG1496	oxidoreductase activity
BC359_RS06430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BC359_RS06435	COG1799	cell septum assembly
BC359_RS06440	COG0762	integral membrane protein
BC359_RS06445	COG2302	S4 RNA-binding domain
BC359_RS06450	COG3599	regulation of cell shape
BC359_RS06465	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BC359_RS06470	COG0564	pseudouridine synthase activity
BC359_RS06475	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BC359_RS06480	COG2233	PERMEase
BC359_RS06485	COG0540	Belongs to the ATCase OTCase family
BC359_RS06490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC359_RS06505	COG0543	2 iron, 2 sulfur cluster binding
BC359_RS06510	COG0167	dihydroorotate dehydrogenase activity
BC359_RS06520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BC359_RS06530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BC359_RS06535	COG1561	YicC-like family, N-terminal region
BC359_RS06540	COG2052	Domain of unknown function (DUF370)
BC359_RS06545	COG0194	GDP metabolic process
BC359_RS06555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC359_RS06560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BC359_RS06565	COG0242	peptide deformylase activity
BC359_RS06570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC359_RS06575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC359_RS06575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BC359_RS06585	COG0631	protein serine/threonine phosphatase activity
BC359_RS06590	COG0515	serine threonine protein kinase
BC359_RS06590	COG2815	serine threonine protein kinase
BC359_RS06600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC359_RS06605	COG1564	THIamine pyrophosphokinase
BC359_RS06615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BC359_RS06620	COG1302	Protein conserved in bacteria
BC359_RS06625	COG1461	Dihydroxyacetone kinase
BC359_RS06635	COG1760	l-serine dehydratase
BC359_RS06640	COG1760	l-serine dehydratase
BC359_RS06645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BC359_RS06650	COG1349	DNA-binding transcription factor activity
BC359_RS06655	COG0416	fatty acid biosynthetic process
BC359_RS06660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BC359_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS06675	COG0571	ribonuclease III activity
BC359_RS06680	COG1196	nuclear chromosome segregation
BC359_RS06685	COG0552	protein localization to endoplasmic reticulum
BC359_RS06695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC359_RS06700	COG0228	four-way junction DNA binding
BC359_RS06705	COG1837	Belongs to the UPF0109 family
BC359_RS06715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BC359_RS06725	COG0335	large ribosomal subunit rRNA binding
BC359_RS06740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BC359_RS06750	COG2257	FlhB HrpN YscU SpaS Family
BC359_RS06760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC359_RS06765	COG0758	DNA mediated transformation
BC359_RS06770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC359_RS06780	COG4974	Belongs to the 'phage' integrase family
BC359_RS06790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BC359_RS06795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BC359_RS06800	COG1815	bacterial-type flagellum-dependent cell motility
BC359_RS06805	COG1558	bacterial-type flagellum-dependent cell motility
BC359_RS06810	COG1677	Flagellar hook-basal body complex protein FliE
BC359_RS06815	COG1766	The M ring may be actively involved in energy transduction
BC359_RS06820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC359_RS06825	COG1317	bacterial-type flagellum organization
BC359_RS06830	COG1157	protein secretion by the type III secretion system
BC359_RS06835	COG2882	bacterial-type flagellum organization
BC359_RS06850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BC359_RS06855	COG4786	Flagellar basal body rod
BC359_RS06860	COG1582	Flagellar protein (FlbD)
BC359_RS06865	COG1580	Controls the rotational direction of flagella during chemotaxis
BC359_RS06870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC359_RS06875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC359_RS06875	COG1776	CheC inhibitor of MCP methylation
BC359_RS06880	COG2201	protein-glutamate methylesterase activity
BC359_RS06885	COG3190	flagellar
BC359_RS06890	COG1338	Plays a role in the flagellum-specific transport system
BC359_RS06895	COG1987	bacterial-type flagellum assembly
BC359_RS06900	COG1684	flagellar biosynthetic protein fliR
BC359_RS06905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC359_RS06910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC359_RS06915	COG1419	protein localization to endoplasmic reticulum
BC359_RS06920	COG0455	bacterial-type flagellum organization
BC359_RS06925	COG2201	protein-glutamate methylesterase activity
BC359_RS06930	COG2198	Histidine kinase
BC359_RS06930	COG0643	Histidine kinase
BC359_RS06935	COG0835	chemotaxis
BC359_RS06940	COG1776	CheC inhibitor of MCP methylation
BC359_RS06945	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BC359_RS06950	COG1191	sigma factor activity
BC359_RS06965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BC359_RS06975	COG0233	cytoplasmic translational termination
BC359_RS06985	COG4589	Belongs to the CDS family
BC359_RS06995	COG0750	zinc metalloprotease
BC359_RS07000	COG0442	prolyl-tRNA aminoacylation
BC359_RS07005	COG2176	DNA-directed DNA polymerase activity
BC359_RS07020	COG2176	DNA-directed DNA polymerase activity
BC359_RS07025	COG0779	Required for maturation of 30S ribosomal subunits
BC359_RS07030	COG0195	Participates in both transcription termination and antitermination
BC359_RS07035	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BC359_RS07040	COG1358	cellular component organization or biogenesis
BC359_RS07045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BC359_RS07050	COG1550	Protein conserved in bacteria
BC359_RS07055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BC359_RS07065	COG0196	riboflavin kinase activity
BC359_RS07070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BC359_RS07075	COG1185	polyribonucleotide nucleotidyltransferase activity
BC359_RS07080	COG0726	polysaccharide deacetylase
BC359_RS07085	COG0612	Peptidase, M16
BC359_RS07090	COG1873	PFAM PRC-barrel domain
BC359_RS07095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC359_RS07100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC359_RS07105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC359_RS07110	COG0527	aspartate kinase activity
BC359_RS07125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC359_RS07130	COG0740	serine-type endopeptidase activity
BC359_RS07150	COG2188	Transcriptional regulator
BC359_RS07155	COG1744	ABC transporter substrate-binding protein PnrA-like
BC359_RS07160	COG3845	ABC transporter
BC359_RS07165	COG4603	Belongs to the binding-protein-dependent transport system permease family
BC359_RS07170	COG1079	Belongs to the binding-protein-dependent transport system permease family
BC359_RS07175	COG0612	Peptidase, M16
BC359_RS07185	COG0300	oxidoreductase activity
BC359_RS07200	COG1426	Protein conserved in bacteria
BC359_RS07205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BC359_RS07210	COG1058	Belongs to the CinA family
BC359_RS07210	COG1546	Belongs to the CinA family
BC359_RS07225	COG1692	metallophosphoesterase
BC359_RS07230	COG2359	stage V sporulation protein S
BC359_RS07240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BC359_RS07240	COG0674	pyruvate-flavodoxin oxidoreductase activity
BC359_RS07245	COG1013	pyruvate-flavodoxin oxidoreductase activity
BC359_RS07255	COG0156	8-amino-7-oxononanoate synthase activity
BC359_RS07260	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC359_RS07265	COG4550	Control of competence regulator ComK, YlbF/YmcA
BC359_RS07275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BC359_RS07290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BC359_RS07300	COG0464	growth
BC359_RS07305	COG2860	membrane
BC359_RS07310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC359_RS07315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BC359_RS07320	COG0789	Transcriptional regulator
BC359_RS07325	COG0174	glutamine synthetase
BC359_RS07330	COG0582	viral genome integration into host DNA
BC359_RS07335	COG2856	Zn peptidase
BC359_RS07380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC359_RS07400	COG0583	DNA-binding transcription factor activity
BC359_RS07405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_RS07410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC359_RS07415	COG1587	Uroporphyrinogen-III synthase
BC359_RS07420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC359_RS07425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BC359_RS07440	COG1982	Orn Lys Arg decarboxylase major
BC359_RS07450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC359_RS07450	COG1017	nitric oxide dioxygenase activity
BC359_RS07455	COG1959	2 iron, 2 sulfur cluster binding
BC359_RS07480	COG1271	oxidase subunit
BC359_RS07485	COG1294	oxidase, subunit
BC359_RS07490	COG1271	oxidase subunit
BC359_RS07495	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BC359_RS07535	COG0531	amino acid
BC359_RS07540	COG1846	Transcriptional regulator
BC359_RS07545	COG0456	acetyltransferase
BC359_RS07555	COG1078	dGTPase activity
BC359_RS07555	COG1078	dGTPase activity
BC359_RS07560	COG0662	Cupin 2, conserved barrel domain protein
BC359_RS07565	COG2814	Major facilitator Superfamily
BC359_RS07575	COG0531	amino acid
BC359_RS07595	COG0659	secondary active sulfate transmembrane transporter activity
BC359_RS07595	COG0659	secondary active sulfate transmembrane transporter activity
BC359_RS07605	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BC359_RS07625	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC359_RS07625	COG3409	Peptidoglycan-binding domain 1 protein
BC359_RS07635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC359_RS07645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_RS07650	COG4224	UPF0291 protein
BC359_RS07665	COG3763	UPF0154 protein
BC359_RS07670	COG1132	(ABC) transporter
BC359_RS07675	COG1132	(ABC) transporter
BC359_RS07685	COG0785	Cytochrome C biogenesis protein
BC359_RS07690	COG2201	protein-glutamate methylesterase activity
BC359_RS07695	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BC359_RS07710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC359_RS07725	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS07730	COG1966	Carbon starvation protein
BC359_RS07740	COG5002	protein histidine kinase activity
BC359_RS07750	COG3142	Participates in the control of copper homeostasis
BC359_RS07760	COG0076	glutamate decarboxylase activity
BC359_RS07795	COG0788	formyltetrahydrofolate deformylase activity
BC359_RS07800	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BC359_RS07805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC359_RS07820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC359_RS07830	COG1307	EDD domain protein, DegV family
BC359_RS07835	COG5002	protein histidine kinase activity
BC359_RS07840	COG1999	signal sequence binding
BC359_RS07845	COG2755	lipolytic protein G-D-S-L family
BC359_RS07870	COG4191	Histidine kinase
BC359_RS07880	COG0577	efflux transmembrane transporter activity
BC359_RS07885	COG1136	(ABC) transporter
BC359_RS07890	COG2205	protein histidine kinase activity
BC359_RS07895	COG0745	RESPONSE REGULATOR receiver
BC359_RS07900	COG1301	dicarboxylic acid transport
BC359_RS07905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC359_RS07910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC359_RS07915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC359_RS07925	COG1509	lysine 2,3-aminomutase activity
BC359_RS07940	COG3594	Acyltransferase
BC359_RS07970	COG0515	serine threonine protein kinase
BC359_RS07975	COG4326	sporulation control protein
BC359_RS07980	COG0671	phosphoesterase, PA-phosphatase related
BC359_RS07990	COG0813	purine-nucleoside phosphorylase activity
BC359_RS07995	COG0659	secondary active sulfate transmembrane transporter activity
BC359_RS08005	COG0772	Belongs to the SEDS family
BC359_RS08025	COG2190	(PTS) system
BC359_RS08030	COG3711	transcriptional antiterminator
BC359_RS08035	COG1263	PTS System
BC359_RS08035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS08050	COG0706	membrane insertase activity
BC359_RS08060	COG0456	acetyltransferase
BC359_RS08065	COG4555	ABC transporter
BC359_RS08075	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_RS08090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_RS08125	COG0697	spore germination
BC359_RS08130	COG0432	Pfam Uncharacterised protein family UPF0047
BC359_RS08135	COG0791	NLP P60 protein
BC359_RS08135	COG1388	LysM domain
BC359_RS08140	COG0205	6-phosphofructokinase activity
BC359_RS08145	COG0589	response to stress
BC359_RS08150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BC359_RS08160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BC359_RS08170	COG1253	flavin adenine dinucleotide binding
BC359_RS08175	COG2340	Cysteine-rich secretory protein family
BC359_RS08180	COG0668	transmembrane transport
BC359_RS08185	COG2323	membrane
BC359_RS08195	COG2514	catechol 2,3-dioxygenase activity
BC359_RS08210	COG2205	protein histidine kinase activity
BC359_RS08215	COG1609	Transcriptional regulator
BC359_RS08235	COG0395	ABC-type sugar transport system, permease component
BC359_RS08240	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BC359_RS08245	COG1737	Transcriptional regulator
BC359_RS08250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS08250	COG1263	PTS System
BC359_RS08260	COG3876	Protein conserved in bacteria
BC359_RS08265	COG1472	Belongs to the glycosyl hydrolase 3 family
BC359_RS08275	COG1309	transcriptional regulator
BC359_RS08280	COG2814	Major facilitator Superfamily
BC359_RS08305	COG0517	IMP dehydrogenase activity
BC359_RS08305	COG1125	glycine betaine transport
BC359_RS08310	COG1174	glycine betaine transport
BC359_RS08330	COG0006	proline dipeptidase activity
BC359_RS08355	COG0789	Transcriptional regulator
BC359_RS08360	COG1607	acyl-coa hydrolase
BC359_RS08365	COG2247	cell wall binding repeat
BC359_RS08365	COG2385	sporulation resulting in formation of a cellular spore
BC359_RS08370	COG2205	protein histidine kinase activity
BC359_RS08370	COG2770	Histidine kinase
BC359_RS08375	COG0745	RESPONSE REGULATOR receiver
BC359_RS08380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC359_RS08390	COG1522	sequence-specific DNA binding
BC359_RS08395	COG0569	domain protein
BC359_RS08400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC359_RS08410	COG1404	Belongs to the peptidase S8 family
BC359_RS08415	COG0840	transmembrane signaling receptor activity
BC359_RS08420	COG0791	NLP P60 protein
BC359_RS08420	COG1388	LysM domain
BC359_RS08445	COG1216	Glycosyl transferase, family 2
BC359_RS08450	COG2259	Doxx family
BC359_RS08465	COG4980	gas vesicle protein
BC359_RS08475	COG1764	response to oxidative stress
BC359_RS08490	COG0454	-acetyltransferase
BC359_RS08495	COG2814	Major facilitator Superfamily
BC359_RS08505	COG4195	phage-related replication protein
BC359_RS08510	COG3226	Transcriptional regulator
BC359_RS08520	COG0861	Integral membrane protein TerC family
BC359_RS08525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BC359_RS08525	COG2755	lipolytic protein G-D-S-L family
BC359_RS08540	COG0561	phosphatase activity
BC359_RS08570	COG1937	Protein conserved in bacteria
BC359_RS08575	COG2608	mercury ion transmembrane transporter activity
BC359_RS08580	COG2217	Heavy metal translocating P-type atpase
BC359_RS08585	COG2312	Erythromycin esterase
BC359_RS08590	COG0346	lactoylglutathione lyase activity
BC359_RS08600	COG4948	Mandelate Racemase Muconate Lactonizing
BC359_RS08635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_RS08640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC359_RS08660	COG4335	DNA alkylation repair
BC359_RS08665	COG1187	pseudouridine synthase activity
BC359_RS08680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_RS08685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_RS08690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC359_RS08695	COG1120	ATPase activity
BC359_RS08710	COG1114	Component of the transport system for branched-chain amino acids
BC359_RS08720	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BC359_RS08730	COG0640	Transcriptional regulator
BC359_RS08740	COG0405	Gamma-glutamyltransferase
BC359_RS08745	COG1253	flavin adenine dinucleotide binding
BC359_RS08750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC359_RS08765	COG0024	Methionine aminopeptidase
BC359_RS08775	COG0346	lactoylglutathione lyase activity
BC359_RS08780	COG2807	transmembrane transport
BC359_RS08790	COG1609	Transcriptional regulator
BC359_RS08800	COG2814	Major facilitator Superfamily
BC359_RS08810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC359_RS08815	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC359_RS08820	COG3695	enzyme binding
BC359_RS08845	COG1609	Transcriptional regulator
BC359_RS08850	COG2211	Major facilitator Superfamily
BC359_RS08870	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC359_RS08895	COG2244	polysaccharide biosynthetic process
BC359_RS08905	COG0604	alcohol dehydrogenase
BC359_RS08905	COG3321	synthase
BC359_RS08910	COG1979	alcohol dehydrogenase
BC359_RS08920	COG1309	transcriptional regulator
BC359_RS08925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_RS08935	COG1846	Transcriptional regulator
BC359_RS08940	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BC359_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS08965	COG0371	Dehydrogenase
BC359_RS08980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BC359_RS08995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BC359_RS09000	COG2186	Transcriptional regulator
BC359_RS09030	COG1278	Cold shock
BC359_RS09035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BC359_RS09040	COG2076	Multidrug Resistance protein
BC359_RS09050	COG4195	phage-related replication protein
BC359_RS09065	COG1742	UPF0060 membrane protein
BC359_RS09070	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BC359_RS09085	COG0456	acetyltransferase
BC359_RS09095	COG1464	Belongs to the NlpA lipoprotein family
BC359_RS09105	COG2011	ABC-type metal ion transport system permease component
BC359_RS09110	COG0039	L-malate dehydrogenase activity
BC359_RS09140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BC359_RS09145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BC359_RS09165	COG5566	PFAM Mor transcription activator
BC359_RS09205	COG2357	RelA SpoT domain protein
BC359_RS09215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_RS09220	COG0730	response to heat
BC359_RS09225	COG3764	Sortase (surface protein transpeptidase)
BC359_RS09240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BC359_RS09255	COG1937	Protein conserved in bacteria
BC359_RS09270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC359_RS09280	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BC359_RS09305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_RS09310	COG1316	TRANSCRIPTIONal
BC359_RS09330	COG2814	Major facilitator Superfamily
BC359_RS09335	COG1309	transcriptional regulator
BC359_RS09340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC359_RS09370	COG0583	DNA-binding transcription factor activity
BC359_RS09375	COG0372	Belongs to the citrate synthase family
BC359_RS09405	COG1597	lipid kinase activity
BC359_RS09425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BC359_RS09440	COG2318	DinB family
BC359_RS09445	COG0733	neurotransmitter:sodium symporter activity
BC359_RS09450	COG2002	toxin-antitoxin pair type II binding
BC359_RS09460	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BC359_RS09465	COG4991	sh3 domain protein
BC359_RS09465	COG3103	Sh3 type 3 domain protein
BC359_RS09465	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS09470	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS09470	COG4991	sh3 domain protein
BC359_RS09470	COG3103	Sh3 type 3 domain protein
BC359_RS09495	COG0640	Transcriptional regulator
BC359_RS09515	COG0681	Belongs to the peptidase S26 family
BC359_RS09520	COG1902	pentaerythritol trinitrate reductase activity
BC359_RS09525	COG0730	response to heat
BC359_RS09550	COG0754	glutathionylspermidine amidase activity
BC359_RS09570	COG0733	neurotransmitter:sodium symporter activity
BC359_RS09580	COG0753	catalase activity
BC359_RS09585	COG0791	NLP P60 protein
BC359_RS09585	COG1388	LysM domain
BC359_RS09590	COG0011	TIGRFAM Protein of
BC359_RS09595	COG2508	Transcriptional regulator
BC359_RS09610	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC359_RS09620	COG2059	Chromate
BC359_RS09625	COG2059	Chromate
BC359_RS09630	COG1605	Chorismate mutase
BC359_RS09630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC359_RS09640	COG0287	Prephenate dehydrogenase
BC359_RS09655	COG0723	plastoquinol--plastocyanin reductase activity
BC359_RS09655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC359_RS09675	COG0517	IMP dehydrogenase activity
BC359_RS09675	COG0516	GMP reductase activity
BC359_RS09685	COG1695	Transcriptional regulator
BC359_RS09690	COG2059	Chromate
BC359_RS09700	COG1253	flavin adenine dinucleotide binding
BC359_RS09705	COG3878	Protein conserved in bacteria
BC359_RS09710	COG5577	PFAM Coat F domain
BC359_RS09720	COG0783	Belongs to the Dps family
BC359_RS09755	COG1132	(ABC) transporter
BC359_RS09775	COG5002	protein histidine kinase activity
BC359_RS09780	COG0745	RESPONSE REGULATOR receiver
BC359_RS09785	COG1469	GTP cyclohydrolase I activity
BC359_RS09790	COG2244	polysaccharide biosynthetic process
BC359_RS09795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_RS09800	COG0400	carboxylic ester hydrolase activity
BC359_RS09815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BC359_RS09820	COG0778	Nitroreductase
BC359_RS09825	COG1388	LysM domain
BC359_RS09825	COG3584	3D domain protein
BC359_RS09845	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BC359_RS09855	COG0831	urea catabolic process
BC359_RS09860	COG0832	Belongs to the urease beta subunit family
BC359_RS09905	COG1233	COG1233 Phytoene dehydrogenase and related
BC359_RS09915	COG1301	dicarboxylic acid transport
BC359_RS09920	COG2404	hydrolase activity, acting on ester bonds
BC359_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS09930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BC359_RS09935	COG1733	regulation of RNA biosynthetic process
BC359_RS09950	COG4145	pantothenate transmembrane transporter activity
BC359_RS09955	COG1492	cobalamin metabolic process
BC359_RS09960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_RS09965	COG4604	ABC transporter, ATP-binding protein
BC359_RS09980	COG1960	acyl-CoA dehydrogenase activity
BC359_RS09995	COG1215	transferase activity, transferring glycosyl groups
BC359_RS10005	COG1086	Polysaccharide biosynthesis protein
BC359_RS10020	COG2182	Extracellular solute-binding protein
BC359_RS10025	COG1175	transmembrane transport
BC359_RS10030	COG3833	ABC-type maltose transport systems, permease component
BC359_RS10045	COG0438	transferase activity, transferring glycosyl groups
BC359_RS10050	COG1216	Glycosyl transferase, family 2
BC359_RS10060	COG0456	acetyltransferase
BC359_RS10060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC359_RS10105	COG2311	Membrane
BC359_RS10115	COG1764	response to oxidative stress
BC359_RS10120	COG0567	Dehydrogenase, E1 component
BC359_RS10125	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC359_RS10145	COG4682	membrane
BC359_RS10155	COG1301	dicarboxylic acid transport
BC359_RS10175	COG2390	Transcriptional regulator
BC359_RS10185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BC359_RS10190	COG0295	cytidine deaminase activity
BC359_RS10195	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC359_RS10205	COG2309	aminopeptidase activity
BC359_RS10245	COG1114	Component of the transport system for branched-chain amino acids
BC359_RS10255	COG1525	nuclease
BC359_RS10280	COG0673	inositol 2-dehydrogenase activity
BC359_RS10285	COG0673	inositol 2-dehydrogenase activity
BC359_RS10290	COG1082	Xylose isomerase domain protein TIM barrel
BC359_RS10295	COG2814	Major facilitator Superfamily
BC359_RS10315	COG0656	L-ascorbic acid biosynthetic process
BC359_RS10330	COG2375	cellular response to nickel ion
BC359_RS10330	COG1132	(ABC) transporter
BC359_RS10335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_RS10345	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC359_RS10355	COG0156	8-amino-7-oxononanoate synthase activity
BC359_RS10360	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BC359_RS10400	COG0444	Belongs to the ABC transporter superfamily
BC359_RS10405	COG4608	Belongs to the ABC transporter superfamily
BC359_RS10415	COG1396	sequence-specific DNA binding
BC359_RS10430	COG1280	lysine exporter protein (LysE YggA)
BC359_RS10435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC359_RS10470	COG0778	Nitroreductase
BC359_RS10480	COG0697	spore germination
BC359_RS10500	COG2814	Major facilitator Superfamily
BC359_RS10500	COG0477	Major facilitator Superfamily
BC359_RS10510	COG2391	methyltransferase activity
BC359_RS10520	COG2814	Major facilitator Superfamily
BC359_RS10555	COG0346	lactoylglutathione lyase activity
BC359_RS10580	COG2188	Transcriptional regulator
BC359_RS10600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC359_RS10605	COG1683	Conserved Protein
BC359_RS10615	COG2814	Major facilitator Superfamily
BC359_RS10620	COG0583	DNA-binding transcription factor activity
BC359_RS10640	COG1917	Cupin 2, conserved barrel domain protein
BC359_RS10640	COG2207	Transcriptional regulator
BC359_RS10675	COG4319	ketosteroid isomerase
BC359_RS10700	COG1263	PTS System
BC359_RS10700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS10720	COG0488	(ABC) transporter
BC359_RS10725	COG0697	spore germination
BC359_RS10730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_RS10765	COG0561	phosphatase activity
BC359_RS10785	COG0456	acetyltransferase
BC359_RS10800	COG0456	acetyltransferase
BC359_RS10820	COG0656	L-ascorbic acid biosynthetic process
BC359_RS10865	COG5444	nuclease activity
BC359_RS10945	COG5444	nuclease activity
BC359_RS10995	COG0617	tRNA 3'-terminal CCA addition
BC359_RS11015	COG0523	cobalamin synthesis protein
BC359_RS11025	COG1937	Protein conserved in bacteria
BC359_RS11030	COG0425	Belongs to the sulfur carrier protein TusA family
BC359_RS11035	COG2210	Belongs to the sulfur carrier protein TusA family
BC359_RS11040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_RS11045	COG0425	Belongs to the sulfur carrier protein TusA family
BC359_RS11045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_RS11050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC359_RS11050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC359_RS11055	COG0425	Belongs to the sulfur carrier protein TusA family
BC359_RS11060	COG0730	response to heat
BC359_RS11065	COG0109	protoheme IX farnesyltransferase activity
BC359_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS11075	COG1309	transcriptional regulator
BC359_RS11080	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC359_RS11090	COG1960	acyl-CoA dehydrogenase activity
BC359_RS11125	COG0393	Putative heavy-metal-binding
BC359_RS11145	COG3583	domain protein
BC359_RS11145	COG3584	3D domain protein
BC359_RS11155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_RS11170	COG2723	6-phospho-beta-galactosidase activity
BC359_RS11190	COG0579	oxidoreductase
BC359_RS11205	COG2329	Antibiotic biosynthesis monooxygenase
BC359_RS11210	COG1278	Cold shock
BC359_RS11230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC359_RS11235	COG0583	DNA-binding transcription factor activity
BC359_RS11350	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC359_RS11365	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_RS11380	COG3973	AAA domain
BC359_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS11390	COG3773	Cell wall hydrolase
BC359_RS11450	COG2204	response regulator
BC359_RS11455	COG3284	Transcriptional regulator
BC359_RS11460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC359_RS11470	COG1595	DNA-templated transcription, initiation
BC359_RS11475	COG0326	Molecular chaperone. Has ATPase activity
BC359_RS11510	COG2124	cytochrome p450
BC359_RS11515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BC359_RS11525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC359_RS11530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC359_RS11550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC359_RS11555	COG2720	vancomycin resistance protein
BC359_RS11560	COG1846	Transcriptional regulator
BC359_RS11570	COG0702	epimerase
BC359_RS11575	COG0494	nUDIX hydrolase
BC359_RS11595	COG0456	acetyltransferase
BC359_RS11600	COG3153	acetyltransferase
BC359_RS11600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_RS11610	COG3883	PFAM NLP P60 protein
BC359_RS11610	COG0791	NLP P60 protein
BC359_RS11615	COG1587	Uroporphyrinogen-III synthase
BC359_RS11620	COG1414	Transcriptional regulator
BC359_RS11625	COG0439	Biotin carboxylase
BC359_RS11630	COG0511	ligase activity, forming carbon-carbon bonds
BC359_RS11635	COG1984	allophanate hydrolase subunit 2
BC359_RS11640	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_RS11645	COG4336	lyase activity
BC359_RS11650	COG1914	H( )-stimulated, divalent metal cation uptake system
BC359_RS11655	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_RS11660	COG0791	NLP P60 protein
BC359_RS11680	COG2197	response regulator
BC359_RS11685	COG4585	Histidine kinase
BC359_RS11685	COG2203	Gaf domain
BC359_RS11700	COG0129	dihydroxy-acid dehydratase activity
BC359_RS11705	COG1227	inorganic diphosphatase activity
BC359_RS11720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC359_RS11730	COG2233	PERMEase
BC359_RS11745	COG1247	-acetyltransferase
BC359_RS11755	COG1011	Hydrolase
BC359_RS11770	COG4974	Belongs to the 'phage' integrase family
BC359_RS11795	COG1335	isochorismatase
BC359_RS11805	COG3403	YqcI/YcgG family
BC359_RS11810	COG2267	carboxylic ester hydrolase activity
BC359_RS11820	COG0187	DNA topoisomerase II activity
BC359_RS11825	COG1832	CoA-binding protein
BC359_RS11830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BC359_RS11835	COG4841	protein insertion into membrane
BC359_RS11840	COG0824	Thioesterase
BC359_RS11865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_RS11870	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC359_RS11895	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BC359_RS11930	COG2814	Major facilitator Superfamily
BC359_RS11935	COG1295	ribonuclease BN
BC359_RS11945	COG2814	Major facilitator Superfamily
BC359_RS11950	COG0789	Transcriptional regulator
BC359_RS11955	COG0659	secondary active sulfate transmembrane transporter activity
BC359_RS11960	COG0454	-acetyltransferase
BC359_RS11975	COG1247	-acetyltransferase
BC359_RS11995	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS12000	COG5002	protein histidine kinase activity
BC359_RS12020	COG0004	ammonium transporteR
BC359_RS12035	COG1252	NADH dehydrogenase
BC359_RS12040	COG0402	S-adenosylhomocysteine deaminase activity
BC359_RS12050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC359_RS12070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC359_RS12085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC359_RS12090	COG0438	transferase activity, transferring glycosyl groups
BC359_RS12105	COG0438	transferase activity, transferring glycosyl groups
BC359_RS12110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC359_RS12145	COG0456	acetyltransferase
BC359_RS12150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC359_RS12160	COG0586	Pfam SNARE associated Golgi protein
BC359_RS12165	COG0534	Mate efflux family protein
BC359_RS12175	COG1164	Oligoendopeptidase f
BC359_RS12180	COG0708	Exodeoxyribonuclease III
BC359_RS12185	COG0737	Belongs to the 5'-nucleotidase family
BC359_RS12200	COG1295	ribonuclease BN
BC359_RS12205	COG1834	amidinotransferase
BC359_RS12210	COG2409	Drug exporters of the RND superfamily
BC359_RS12235	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BC359_RS12240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BC359_RS12245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_RS12270	COG3584	3D domain protein
BC359_RS12270	COG1388	LysM domain
BC359_RS12280	COG1846	Transcriptional regulator
BC359_RS12285	COG1764	response to oxidative stress
BC359_RS12310	COG1131	(ABC) transporter
BC359_RS12315	COG1725	Transcriptional regulator
BC359_RS12320	COG0583	DNA-binding transcription factor activity
BC359_RS12335	COG3546	catalase activity
BC359_RS12340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC359_RS12345	COG1575	Belongs to the MenA family. Type 1 subfamily
BC359_RS12365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC359_RS12375	COG0551	DNA topoisomerase type I activity
BC359_RS12375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC359_RS12400	COG1609	Transcriptional regulator
BC359_RS12420	COG1131	(ABC) transporter
BC359_RS12430	COG0488	(ABC) transporter
BC359_RS12440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC359_RS12445	COG2378	regulation of single-species biofilm formation
BC359_RS12455	COG2223	nitrite transmembrane transporter activity
BC359_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS12465	COG3835	regulator
BC359_RS12475	COG0247	lactate metabolic process
BC359_RS12490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC359_RS12495	COG1335	isochorismatase
BC359_RS12500	COG0494	nUDIX hydrolase
BC359_RS12510	COG1132	(ABC) transporter
BC359_RS12545	COG0297	glycogen (starch) synthase activity
BC359_RS12560	COG1396	sequence-specific DNA binding
BC359_RS12565	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC359_RS12570	COG0110	maltose O-acetyltransferase activity
BC359_RS12575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC359_RS12585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC359_RS12595	COG1215	transferase activity, transferring glycosyl groups
BC359_RS12600	COG0438	transferase activity, transferring glycosyl groups
BC359_RS12605	COG0438	transferase activity, transferring glycosyl groups
BC359_RS12610	COG1086	Polysaccharide biosynthesis protein
BC359_RS12615	COG0489	protein tyrosine kinase activity
BC359_RS12620	COG3944	biosynthesis protein
BC359_RS12635	COG2720	vancomycin resistance protein
BC359_RS12640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC359_RS12665	COG1657	PFAM Prenyltransferase squalene oxidase
BC359_RS12670	COG1119	ATPase activity
BC359_RS12680	COG2207	Transcriptional regulator
BC359_RS12695	COG4548	von Willebrand factor, type A
BC359_RS12700	COG0714	Associated with various cellular activities
BC359_RS12705	COG4873	Protein conserved in bacteria
BC359_RS12710	COG1595	DNA-templated transcription, initiation
BC359_RS12730	COG3871	stress protein (general stress protein 26)
BC359_RS12735	COG0352	thiamine-phosphate diphosphorylase activity
BC359_RS12740	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BC359_RS12755	COG2094	Belongs to the DNA glycosylase MPG family
BC359_RS12765	COG0673	inositol 2-dehydrogenase activity
BC359_RS12770	COG0673	inositol 2-dehydrogenase activity
BC359_RS12785	COG3773	Cell wall hydrolase
BC359_RS12790	COG0733	neurotransmitter:sodium symporter activity
BC359_RS12810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC359_RS12815	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS12825	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS12845	COG2032	superoxide dismutase activity
BC359_RS12855	COG0527	aspartate kinase activity
BC359_RS12860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC359_RS12860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC359_RS12860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC359_RS12865	COG1105	Belongs to the carbohydrate kinase PfkB family
BC359_RS12870	COG1349	DNA-binding transcription factor activity
BC359_RS12880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_RS12890	COG4974	Belongs to the 'phage' integrase family
BC359_RS12895	COG2323	membrane
BC359_RS12900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_RS12910	COG2323	membrane
BC359_RS12925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC359_RS12955	COG5002	protein histidine kinase activity
BC359_RS12965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC359_RS12970	COG2246	polysaccharide biosynthetic process
BC359_RS12975	COG0463	Glycosyl transferase, family 2
BC359_RS12985	COG3546	catalase activity
BC359_RS13005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BC359_RS13010	COG0628	permease
BC359_RS13015	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS13035	COG0493	'glutamate synthase
BC359_RS13040	COG0069	glutamate synthase activity
BC359_RS13040	COG0067	glutamate synthase
BC359_RS13040	COG0070	glutamate synthase
BC359_RS13045	COG0583	DNA-binding transcription factor activity
BC359_RS13060	COG1278	Cold shock
BC359_RS13065	COG3830	Belongs to the UPF0237 family
BC359_RS13070	COG2848	UPF0210 protein
BC359_RS13085	COG3402	PFAM membrane-flanked domain
BC359_RS13090	COG0281	malic enzyme
BC359_RS13095	COG1027	Aspartate ammonia-lyase
BC359_RS13100	COG1611	Belongs to the LOG family
BC359_RS13105	COG2323	membrane
BC359_RS13120	COG0281	malic enzyme
BC359_RS13135	COG3104	oligopeptide transport
BC359_RS13140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BC359_RS13145	COG5002	protein histidine kinase activity
BC359_RS13155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC359_RS13165	COG0833	amino acid
BC359_RS13170	COG1757	Na H antiporter
BC359_RS13175	COG3361	conserved protein (COG2071)
BC359_RS13185	COG1360	Flagellar Motor Protein
BC359_RS13190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC359_RS13195	COG2112	serine threonine protein kinase
BC359_RS13200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BC359_RS13200	COG2124	cytochrome p450
BC359_RS13205	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS13210	COG1823	symporter activity
BC359_RS13220	COG2234	aminopeptidase activity
BC359_RS13245	COG3853	Toxic anion resistance protein (TelA)
BC359_RS13255	COG1368	sulfuric ester hydrolase activity
BC359_RS13260	COG1233	COG1233 Phytoene dehydrogenase and related
BC359_RS13265	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS13275	COG2002	toxin-antitoxin pair type II binding
BC359_RS13300	COG1595	DNA-templated transcription, initiation
BC359_RS13305	COG3011	Protein conserved in bacteria
BC359_RS13310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC359_RS13320	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC359_RS13325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC359_RS13340	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC359_RS13355	COG2962	Rard protein
BC359_RS13360	COG2096	Adenosyltransferase
BC359_RS13370	COG0588	phosphoglycerate mutase activity
BC359_RS13375	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BC359_RS13390	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BC359_RS13400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC359_RS13410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC359_RS13425	COG2136	Putative SAM-dependent methyltransferase
BC359_RS13425	COG2521	methyltransferase
BC359_RS13440	COG1413	lyase activity
BC359_RS13445	COG0488	(ABC) transporter
BC359_RS13450	COG1418	mRNA catabolic process
BC359_RS13455	COG0386	Belongs to the glutathione peroxidase family
BC359_RS13470	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BC359_RS13480	COG2226	methyltransferase
BC359_RS13500	COG1940	carbohydrate kinase activity
BC359_RS13505	COG2182	Extracellular solute-binding protein
BC359_RS13520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC359_RS13520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC359_RS13525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_RS13525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_RS13530	COG2814	Major facilitator Superfamily
BC359_RS13540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC359_RS13555	COG0477	Major facilitator Superfamily
BC359_RS13560	COG1819	glycosyl
BC359_RS13570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC359_RS13610	COG0534	Mate efflux family protein
BC359_RS13615	COG4608	Belongs to the ABC transporter superfamily
BC359_RS13620	COG0444	Belongs to the ABC transporter superfamily
BC359_RS13625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC359_RS13630	COG0601	transmembrane transport
BC359_RS13635	COG0747	negative chemotaxis
BC359_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS13665	COG0561	phosphatase activity
BC359_RS13680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC359_RS13685	COG0640	Transcriptional regulator
BC359_RS13695	COG0640	Transcriptional regulator
BC359_RS13700	COG0346	lactoylglutathione lyase activity
BC359_RS13710	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC359_RS13715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC359_RS13725	COG2271	Major facilitator Superfamily
BC359_RS13730	COG1388	LysM domain
BC359_RS13735	COG0745	RESPONSE REGULATOR receiver
BC359_RS13740	COG5002	protein histidine kinase activity
BC359_RS13745	COG0596	Alpha beta hydrolase
BC359_RS13760	COG2197	response regulator
BC359_RS13765	COG4585	Histidine kinase
BC359_RS13770	COG3239	Fatty acid desaturase
BC359_RS13780	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC359_RS13800	COG4608	Belongs to the ABC transporter superfamily
BC359_RS13805	COG0791	NLP P60 protein
BC359_RS13815	COG4166	transmembrane transport
BC359_RS13820	COG0444	Belongs to the ABC transporter superfamily
BC359_RS13825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC359_RS13830	COG0601	transmembrane transport
BC359_RS13835	COG2362	D-Aminopeptidase
BC359_RS13860	COG2814	Major facilitator Superfamily
BC359_RS13865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC359_RS13885	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_RS13890	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_RS13920	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC359_RS13925	COG1755	Isoprenylcysteine carboxyl methyltransferase
BC359_RS13940	COG2233	PERMEase
BC359_RS13945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC359_RS13950	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BC359_RS13955	COG1199	ATP-dependent helicase activity
BC359_RS13970	COG0116	Belongs to the methyltransferase superfamily
BC359_RS13975	COG0366	Alpha amylase catalytic
BC359_RS13980	COG2197	response regulator
BC359_RS13985	COG4585	Histidine kinase
BC359_RS14010	COG3599	regulation of cell shape
BC359_RS14015	COG4474	Belongs to the UPF0398 family
BC359_RS14025	COG3359	exonuclease
BC359_RS14030	COG1111	helicase
BC359_RS14030	COG1205	dead DEAH box helicase
BC359_RS14045	COG1331	Highly conserved protein containing a thioredoxin domain
BC359_RS14060	COG4607	ABC-type enterochelin transport system periplasmic component
BC359_RS14065	COG4604	ABC transporter, ATP-binding protein
BC359_RS14070	COG4605	iron ion homeostasis
BC359_RS14075	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC359_RS14120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_RS14135	COG0626	cystathionine gamma-synthase activity
BC359_RS14140	COG0626	cystathionine gamma-synthase activity
BC359_RS14145	COG5337	Spore coat protein CotH
BC359_RS14180	COG3331	DNA recombination
BC359_RS14185	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC359_RS14185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_RS14195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BC359_RS14200	COG3935	DnaD domain protein
BC359_RS14205	COG0017	Asparaginyl-tRNA synthetase
BC359_RS14210	COG0436	Aminotransferase
BC359_RS14230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BC359_RS14230	COG1199	ATP-dependent helicase activity
BC359_RS14235	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BC359_RS14240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BC359_RS14245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BC359_RS14255	COG0617	tRNA 3'-terminal CCA addition
BC359_RS14260	COG0438	transferase activity, transferring glycosyl groups
BC359_RS14265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC359_RS14270	COG1803	Methylglyoxal synthase
BC359_RS14275	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BC359_RS14280	COG1694	Mazg nucleotide pyrophosphohydrolase
BC359_RS14285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_RS14290	COG2738	Putative neutral zinc metallopeptidase
BC359_RS14300	COG2340	Cysteine-rich secretory protein family
BC359_RS14305	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BC359_RS14315	COG3336	cytochrome c oxidase
BC359_RS14345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC359_RS14350	COG0772	Belongs to the SEDS family
BC359_RS14355	COG4838	Belongs to the UPF0358 family
BC359_RS14360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC359_RS14365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC359_RS14380	COG4896	Protein conserved in bacteria
BC359_RS14395	COG1217	gtp-binding protein TYPA
BC359_RS14405	COG0483	inositol monophosphate 1-phosphatase activity
BC359_RS14415	COG4493	Belongs to the UPF0637 family
BC359_RS14420	COG4476	Belongs to the UPF0223 family
BC359_RS14425	COG1982	Orn Lys Arg decarboxylase major
BC359_RS14440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC359_RS14450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC359_RS14455	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC359_RS14460	COG0022	dehydrogenase e1 component
BC359_RS14480	COG0242	peptide deformylase activity
BC359_RS14485	COG0561	phosphatase activity
BC359_RS14495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC359_RS14510	COG1131	(ABC) transporter
BC359_RS14515	COG2197	response regulator
BC359_RS14520	COG4585	Histidine kinase
BC359_RS14525	COG0569	domain protein
BC359_RS14530	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_RS14535	COG0450	alkyl hydroperoxide reductase
BC359_RS14540	COG0668	transmembrane transport
BC359_RS14545	COG1473	amidohydrolase
BC359_RS14550	COG2171	N-acyltransferase activity
BC359_RS14555	COG0583	DNA-binding transcription factor activity
BC359_RS14560	COG4703	Protein of unknown function (DUF1797)
BC359_RS14575	COG2200	EAL domain
BC359_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS14585	COG1408	metallophosphoesterase
BC359_RS14600	COG0248	Ppx GppA phosphatase
BC359_RS14605	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_RS14615	COG4975	Glucose uptake
BC359_RS14625	COG0784	Response regulator, receiver
BC359_RS14625	COG0835	chemotaxis
BC359_RS14640	COG0436	Aminotransferase
BC359_RS14650	COG2084	Dehydrogenase
BC359_RS14655	COG0778	Nitroreductase
BC359_RS14670	COG0583	DNA-binding transcription factor activity
BC359_RS14675	COG1733	regulation of RNA biosynthetic process
BC359_RS14680	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BC359_RS14685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BC359_RS14695	COG1346	cytolysis
BC359_RS14715	COG1263	PTS System
BC359_RS14715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS14715	COG2190	(PTS) system
BC359_RS14720	COG3711	transcriptional antiterminator
BC359_RS14730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BC359_RS14735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_RS14735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC359_RS14740	COG0307	riboflavin synthase, alpha
BC359_RS14745	COG3949	Membrane
BC359_RS14750	COG4989	oxidoreductase activity
BC359_RS14755	COG0646	methionine synthase
BC359_RS14755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BC359_RS14760	COG1410	methionine synthase
BC359_RS14760	COG0646	methionine synthase
BC359_RS14765	COG1966	Carbon starvation protein
BC359_RS14800	COG5506	Protein of unknown function (DUF1694)
BC359_RS14805	COG3773	Cell wall hydrolase
BC359_RS14825	COG4873	Protein conserved in bacteria
BC359_RS14830	COG0702	epimerase
BC359_RS14835	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BC359_RS14840	COG0602	queuosine metabolic process
BC359_RS14845	COG0720	synthase
BC359_RS14850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BC359_RS14855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BC359_RS14860	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BC359_RS14880	COG0697	spore germination
BC359_RS14885	COG0300	oxidoreductase activity
BC359_RS14895	COG1757	Na H antiporter
BC359_RS14905	COG0542	response to heat
BC359_RS14920	COG1846	Transcriptional regulator
BC359_RS14945	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC359_RS14950	COG1129	ABC transporter
BC359_RS14970	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BC359_RS14975	COG1850	ribulose-bisphosphate carboxylase activity
BC359_RS14980	COG0436	Aminotransferase
BC359_RS14985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_RS14990	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BC359_RS14995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BC359_RS15005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC359_RS15020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC359_RS15025	COG1032	radical SAM domain protein
BC359_RS15030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC359_RS15065	COG0861	Integral membrane protein TerC family
BC359_RS15070	COG0784	Response regulator, receiver
BC359_RS15080	COG3279	Response regulator of the LytR AlgR family
BC359_RS15090	COG1785	Belongs to the alkaline phosphatase family
BC359_RS15110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC359_RS15110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC359_RS15115	COG0477	Major facilitator Superfamily
BC359_RS15120	COG1846	Transcriptional regulator
BC359_RS15135	COG2252	PERMEase
BC359_RS15180	COG0346	lactoylglutathione lyase activity
BC359_RS15190	COG1253	flavin adenine dinucleotide binding
BC359_RS15195	COG4085	toxin activity
BC359_RS15195	COG1525	nuclease
BC359_RS15195	COG0737	Belongs to the 5'-nucleotidase family
BC359_RS15200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BC359_RS15205	COG4988	ABC transporter
BC359_RS15210	COG1294	oxidase, subunit
BC359_RS15215	COG1271	oxidase subunit
BC359_RS15225	COG1063	alcohol dehydrogenase
BC359_RS15230	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_RS15245	COG1131	(ABC) transporter
BC359_RS15270	COG2190	(PTS) system
BC359_RS15270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS15270	COG1263	PTS System
BC359_RS15275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BC359_RS15280	COG0363	glucosamine-6-phosphate deaminase activity
BC359_RS15285	COG2188	Transcriptional regulator
BC359_RS15320	COG0561	phosphatase activity
BC359_RS15325	COG1609	Transcriptional regulator
BC359_RS15330	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BC359_RS15365	COG3314	Sporulation integral membrane protein YlbJ
BC359_RS15370	COG4948	Mandelate Racemase Muconate Lactonizing
BC359_RS15380	COG1737	Transcriptional regulator
BC359_RS15385	COG1473	amidohydrolase
BC359_RS15405	COG0861	Integral membrane protein TerC family
BC359_RS15505	COG5444	nuclease activity
BC359_RS15520	COG1959	2 iron, 2 sulfur cluster binding
BC359_RS15525	COG0702	epimerase
BC359_RS15535	COG5577	PFAM Coat F domain
BC359_RS15540	COG1063	alcohol dehydrogenase
BC359_RS15550	COG5577	PFAM Coat F domain
BC359_RS15560	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS15600	COG0489	protein tyrosine kinase activity
BC359_RS15605	COG3944	biosynthesis protein
BC359_RS15610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC359_RS15615	COG1482	cell wall glycoprotein biosynthetic process
BC359_RS15630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC359_RS15655	COG0438	transferase activity, transferring glycosyl groups
BC359_RS15665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC359_RS15670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC359_RS15675	COG4464	protein tyrosine phosphatase activity
BC359_RS15700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC359_RS15735	COG1309	transcriptional regulator
BC359_RS15745	COG0840	transmembrane signaling receptor activity
BC359_RS15750	COG0791	NLP P60 protein
BC359_RS15760	COG5001	Diguanylate cyclase
BC359_RS15760	COG5002	protein histidine kinase activity
BC359_RS15760	COG3447	MASE1 domain protein
BC359_RS15770	COG1472	Belongs to the glycosyl hydrolase 3 family
BC359_RS15775	COG4640	response to antibiotic
BC359_RS15785	COG4640	response to antibiotic
BC359_RS15800	COG4842	Belongs to the WXG100 family
BC359_RS15805	COG0753	catalase activity
BC359_RS15830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC359_RS15835	COG3300	MHYT domain
BC359_RS15835	COG5001	Diguanylate cyclase
BC359_RS15845	COG1131	(ABC) transporter
BC359_RS15850	COG1725	Transcriptional regulator
BC359_RS15865	COG3718	enzyme involved in inositol metabolism
BC359_RS15890	COG0673	inositol 2-dehydrogenase activity
BC359_RS15895	COG2814	Major facilitator Superfamily
BC359_RS15900	COG0673	inositol 2-dehydrogenase activity
BC359_RS15915	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC359_RS15920	COG1129	ABC transporter
BC359_RS15935	COG0154	amidase activity
BC359_RS15945	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_RS15960	COG0492	ferredoxin-NADP+ reductase activity
BC359_RS15975	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BC359_RS15980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_RS15990	COG0628	permease
BC359_RS16060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC359_RS16085	COG0673	inositol 2-dehydrogenase activity
BC359_RS16105	COG1278	Cold shock
BC359_RS16110	COG0402	S-adenosylhomocysteine deaminase activity
BC359_RS16130	COG1272	protein, Hemolysin III
BC359_RS16140	COG0701	Predicted permease
BC359_RS16145	COG1914	H( )-stimulated, divalent metal cation uptake system
BC359_RS16150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_RS16155	COG1984	allophanate hydrolase subunit 2
BC359_RS16160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC359_RS16165	COG2188	Transcriptional regulator
BC359_RS16170	COG0366	Alpha amylase catalytic
BC359_RS16180	COG0697	spore germination
BC359_RS16190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BC359_RS16195	COG2252	PERMEase
BC359_RS16200	COG0402	S-adenosylhomocysteine deaminase activity
BC359_RS16220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC359_RS16230	COG0406	alpha-ribazole phosphatase activity
BC359_RS16240	COG0716	FMN binding
BC359_RS16260	COG5002	protein histidine kinase activity
BC359_RS16300	COG3583	domain protein
BC359_RS16300	COG3584	3D domain protein
BC359_RS16305	COG1879	ABC-type sugar transport system periplasmic component
BC359_RS16310	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC359_RS16315	COG1129	ABC transporter
BC359_RS16320	COG1869	D-ribose catabolic process
BC359_RS16325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC359_RS16330	COG1609	Transcriptional regulator
BC359_RS16335	COG0656	L-ascorbic acid biosynthetic process
BC359_RS16340	COG1414	Transcriptional regulator
BC359_RS16360	COG3162	membrane
BC359_RS16365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_RS16380	COG1733	regulation of RNA biosynthetic process
BC359_RS16385	COG1511	domain protein
BC359_RS16390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC359_RS16395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC359_RS16400	COG1116	anion transmembrane transporter activity
BC359_RS16405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC359_RS16410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC359_RS16415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC359_RS16425	COG2226	methyltransferase
BC359_RS16430	COG3180	Ammonia monooxygenase
BC359_RS16435	COG0583	DNA-binding transcription factor activity
BC359_RS16440	COG3181	Tripartite tricarboxylate transporter family receptor
BC359_RS16445	COG4565	transcriptional regulatory protein
BC359_RS16450	COG3290	protein histidine kinase activity
BC359_RS16455	COG2851	Citrate transporter
BC359_RS16475	COG3290	protein histidine kinase activity
BC359_RS16480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BC359_RS16485	COG1301	dicarboxylic acid transport
BC359_RS16500	COG3773	Cell wall hydrolase
BC359_RS16515	COG0577	efflux transmembrane transporter activity
BC359_RS16520	COG1136	(ABC) transporter
BC359_RS16525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BC359_RS16540	COG1607	acyl-coa hydrolase
BC359_RS16550	COG4297	protein containing double-stranded beta helix domain
BC359_RS16555	COG2814	Major facilitator Superfamily
BC359_RS16560	COG1733	regulation of RNA biosynthetic process
BC359_RS16565	COG4895	conserved protein (DUF2196)
BC359_RS16570	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_RS16575	COG1620	l-lactate permease
BC359_RS16580	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC359_RS16585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC359_RS16590	COG0277	FAD linked oxidase domain protein
BC359_RS16595	COG0247	lactate metabolic process
BC359_RS16605	COG2186	Transcriptional regulator
BC359_RS16610	COG0735	belongs to the Fur family
BC359_RS16620	COG1595	DNA-templated transcription, initiation
BC359_RS16640	COG0697	spore germination
BC359_RS16645	COG1802	Transcriptional regulator
BC359_RS16650	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_RS16650	COG2202	Pas domain
BC359_RS16660	COG2116	formate transmembrane transporter activity
BC359_RS16670	COG2146	nitrite reductase [NAD(P)H] activity
BC359_RS16675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC359_RS16680	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC359_RS16685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC359_RS16690	COG1121	(ABC) transporter
BC359_RS16740	COG0582	viral genome integration into host DNA
BC359_RS16745	COG0582	viral genome integration into host DNA
BC359_RS16770	COG1070	Carbohydrate kinase
BC359_RS16775	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_RS16780	COG1737	Transcriptional regulator
BC359_RS16790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC359_RS16800	COG2382	esterase
BC359_RS16810	COG2153	protein acetylation
BC359_RS16825	COG2323	membrane
BC359_RS16835	COG0210	DNA helicase
BC359_RS16890	COG0569	domain protein
BC359_RS16890	COG0475	glutathione-regulated potassium exporter activity
BC359_RS16895	COG2239	Acts as a magnesium transporter
BC359_RS16900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC359_RS16905	COG0564	pseudouridine synthase activity
BC359_RS16915	COG2357	RelA SpoT domain protein
BC359_RS16925	COG4116	CYTH
BC359_RS16930	COG0741	lytic transglycosylase activity
BC359_RS16935	COG2346	COG2346, Truncated hemoglobins
BC359_RS16940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC359_RS16945	COG1164	Oligoendopeptidase f
BC359_RS16955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC359_RS16965	COG0861	Integral membrane protein TerC family
BC359_RS16970	COG1393	Belongs to the ArsC family
BC359_RS16985	COG0456	acetyltransferase
BC359_RS16990	COG4608	Belongs to the ABC transporter superfamily
BC359_RS16995	COG0444	Belongs to the ABC transporter superfamily
BC359_RS17000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC359_RS17005	COG0601	transmembrane transport
BC359_RS17010	COG4166	transmembrane transport
BC359_RS17015	COG0180	Tryptophanyl-tRNA synthetase
BC359_RS17025	COG5504	Zn-dependent protease
BC359_RS17030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC359_RS17035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC359_RS17055	COG2267	carboxylic ester hydrolase activity
BC359_RS17065	COG1874	Beta-galactosidase
BC359_RS17070	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BC359_RS17075	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC359_RS17080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BC359_RS17105	COG0542	response to heat
BC359_RS17120	COG0702	epimerase
BC359_RS17125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BC359_RS17135	COG0505	Belongs to the CarA family
BC359_RS17145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BC359_RS17150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BC359_RS17155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BC359_RS17160	COG2151	metal-sulfur cluster biosynthetic enzyme
BC359_RS17170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_RS17175	COG1307	EDD domain protein, DegV family
BC359_RS17185	COG2996	Protein conserved in bacteria
BC359_RS17190	COG1666	GTP binding
BC359_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS17200	COG3829	transcription factor binding
BC359_RS17205	COG4187	Peptidase family M20/M25/M40
BC359_RS17210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC359_RS17215	COG1012	belongs to the aldehyde dehydrogenase family
BC359_RS17220	COG1609	Transcriptional regulator
BC359_RS17225	COG0366	Alpha amylase catalytic
BC359_RS17230	COG0004	ammonium transporteR
BC359_RS17235	COG0347	Belongs to the P(II) protein family
BC359_RS17240	COG1562	ergosterol biosynthetic process
BC359_RS17255	COG0367	asparagine synthase
BC359_RS17300	COG1403	HNH endonuclease
BC359_RS17305	COG0419	ATPase involved in DNA repair
BC359_RS17310	COG0420	3'-5' exonuclease activity
BC359_RS17315	COG1074	ATP-dependent DNA helicase activity
BC359_RS17330	COG0398	Pfam SNARE associated Golgi protein
BC359_RS17400	COG2224	Isocitrate lyase
BC359_RS17405	COG0501	Belongs to the peptidase M48B family
BC359_RS17410	COG1024	Enoyl-CoA hydratase
BC359_RS17415	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_RS17420	COG0095	Lipoate-protein ligase
BC359_RS17425	COG1234	tRNA 3'-trailer cleavage
BC359_RS17440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC359_RS17445	COG2207	Transcriptional regulator
BC359_RS17450	COG2972	Histidine kinase
BC359_RS17460	COG0768	penicillin binding
BC359_RS17465	COG1309	transcriptional regulator
BC359_RS17470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BC359_RS17475	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BC359_RS17480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BC359_RS17485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC359_RS17490	COG2329	Antibiotic biosynthesis monooxygenase
BC359_RS17495	COG3069	C4-dicarboxylate transmembrane transporter activity
BC359_RS17545	COG3409	Peptidoglycan-binding domain 1 protein
BC359_RS17545	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC359_RS17545	COG1388	LysM domain
BC359_RS17620	COG0740	serine-type endopeptidase activity
BC359_RS17710	COG0305	Participates in initiation and elongation during chromosome replication
BC359_RS17745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC359_RS17750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC359_RS17760	COG1473	amidohydrolase
BC359_RS17770	COG4473	ABC transporter
BC359_RS17775	COG1131	(ABC) transporter
BC359_RS17780	COG0537	adenosine 5'-monophosphoramidase activity
BC359_RS17785	COG2153	protein acetylation
BC359_RS17795	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BC359_RS17810	COG1846	Transcriptional regulator
BC359_RS17835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BC359_RS17850	COG1668	transmembrane transport
BC359_RS17855	COG4152	abc transporter atp-binding protein
BC359_RS17870	COG1024	Enoyl-CoA hydratase
BC359_RS17875	COG0318	PFAM AMP-dependent synthetase and ligase
BC359_RS17880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC359_RS17885	COG0561	phosphatase activity
BC359_RS17895	COG1131	(ABC) transporter
BC359_RS17910	COG3679	Belongs to the UPF0342 family
BC359_RS17915	COG4399	Belongs to the UPF0754 family
BC359_RS17920	COG0189	ligase activity
BC359_RS17925	COG0189	ligase activity
BC359_RS17930	COG0189	ligase activity
BC359_RS17935	COG0189	ligase activity
BC359_RS17945	COG2508	Transcriptional regulator
BC359_RS17950	COG3842	ATPase activity
BC359_RS17965	COG1253	flavin adenine dinucleotide binding
BC359_RS17970	COG0702	epimerase
BC359_RS17975	COG0351	phosphomethylpyrimidine kinase
BC359_RS17980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC359_RS17985	COG2022	thiamine diphosphate biosynthetic process
BC359_RS17995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC359_RS18010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC359_RS18015	COG0765	amino acid transport
BC359_RS18020	COG1126	abc transporter atp-binding protein
BC359_RS18025	COG0604	alcohol dehydrogenase
BC359_RS18035	COG2719	SpoVR family
BC359_RS18045	COG1268	BioY protein
BC359_RS18050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC359_RS18055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC359_RS18060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BC359_RS18065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC359_RS18070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC359_RS18100	COG0840	transmembrane signaling receptor activity
BC359_RS18105	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC359_RS18110	COG0584	glycerophosphoryl diester phosphodiesterase
BC359_RS18130	COG3842	ATPase activity
BC359_RS18135	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC359_RS18145	COG3290	protein histidine kinase activity
BC359_RS18145	COG3829	transcription factor binding
BC359_RS18150	COG2610	gluconate transmembrane transporter activity
BC359_RS18155	COG2217	Heavy metal translocating P-type atpase
BC359_RS18160	COG0586	Pfam SNARE associated Golgi protein
BC359_RS18165	COG0628	permease
BC359_RS18170	COG1301	dicarboxylic acid transport
BC359_RS18175	COG1968	undecaprenyl-diphosphatase activity
BC359_RS18180	COG1114	Component of the transport system for branched-chain amino acids
BC359_RS18190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BC359_RS18205	COG0697	spore germination
BC359_RS18210	COG0688	phosphatidylethanolamine metabolic process
BC359_RS18220	COG1846	Transcriptional regulator
BC359_RS18225	COG2718	Belongs to the UPF0229 family
BC359_RS18230	COG2766	serine protein kinase
BC359_RS18235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BC359_RS18250	COG3382	B3 4 domain protein
BC359_RS18260	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BC359_RS18315	COG4974	Belongs to the 'phage' integrase family
BC359_RS18345	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BC359_RS18530	COG0735	belongs to the Fur family
BC359_RS18535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC359_RS18560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BC359_RS18565	COG4129	membrane
BC359_RS18570	COG1132	(ABC) transporter
BC359_RS18590	COG1028	Short-chain dehydrogenase reductase Sdr
BC359_RS18600	COG1194	a g-specific adenine glycosylase
BC359_RS18605	COG1988	membrane-bound metal-dependent
BC359_RS18625	COG4221	oxidoreductase activity
BC359_RS18630	COG2137	regulation of response to DNA damage stimulus
BC359_RS18650	COG1090	epimerase
BC359_RS18675	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC359_RS18685	COG0840	transmembrane signaling receptor activity
BC359_RS18690	COG0778	Nitroreductase
BC359_RS18700	COG1280	lysine exporter protein (LysE YggA)
BC359_RS18705	COG0778	Nitroreductase
BC359_RS18715	COG0745	RESPONSE REGULATOR receiver
BC359_RS18720	COG5002	protein histidine kinase activity
BC359_RS18725	COG0577	efflux transmembrane transporter activity
BC359_RS18730	COG1136	(ABC) transporter
BC359_RS18735	COG1113	amino acid transport
BC359_RS18750	COG3844	kynureninase activity
BC359_RS18760	COG1309	transcriptional regulator
BC359_RS18770	COG1126	abc transporter atp-binding protein
BC359_RS18775	COG0765	amino acid transport
BC359_RS18785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC359_RS18835	COG1131	(ABC) transporter
BC359_RS18850	COG3279	Response regulator of the LytR AlgR family
BC359_RS18860	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC359_RS18865	COG2079	MmgE PrpD family protein
BC359_RS18870	COG0372	Belongs to the citrate synthase family
BC359_RS18885	COG0494	nUDIX hydrolase
BC359_RS18930	COG4974	Belongs to the 'phage' integrase family
BC359_RS18955	COG1192	Involved in chromosome partitioning
BC359_RS18960	COG3048	D-serine ammonia-lyase activity
BC359_RS18980	COG2610	gluconate transmembrane transporter activity
BC359_RS18985	COG0191	fructose-bisphosphate aldolase activity
BC359_RS18995	COG2084	Dehydrogenase
BC359_RS19000	COG1802	Transcriptional regulator
BC359_RS19020	COG1982	Orn Lys Arg decarboxylase major
BC359_RS19030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC359_RS19035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC359_RS19040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC359_RS19040	COG1263	PTS System
BC359_RS19050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC359_RS19075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC359_RS19090	COG2365	Tyrosine phosphatase family
BC359_RS19120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BC359_RS19135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC359_RS19140	COG0697	spore germination
BC359_RS19145	COG0662	Cupin 2, conserved barrel domain protein
BC359_RS19145	COG2207	Transcriptional regulator
BC359_RS19150	COG1929	Belongs to the glycerate kinase type-1 family
BC359_RS19160	COG3835	regulator
BC359_RS19165	COG0583	DNA-binding transcription factor activity
BC359_RS19170	COG2814	Major facilitator Superfamily
BC359_RS19180	COG1253	flavin adenine dinucleotide binding
BC359_RS19195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BC359_RS19205	COG0477	Major facilitator Superfamily
BC359_RS19215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BC359_RS19230	COG2318	DinB family
BC359_RS19235	COG1051	belongs to the nudix hydrolase family
BC359_RS19245	COG0535	radical SAM domain protein
BC359_RS19255	COG0387	Pfam Sodium calcium exchanger
BC359_RS19260	COG3871	stress protein (general stress protein 26)
BC359_RS19305	COG0477	Major facilitator Superfamily
BC359_RS19315	COG0640	Transcriptional regulator
BC359_RS19325	COG2217	Heavy metal translocating P-type atpase
BC359_RS19330	COG1295	ribonuclease BN
BC359_RS19335	COG4980	gas vesicle protein
BC359_RS19340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC359_RS19345	COG4840	Belongs to the UPF0435 family
BC359_RS19350	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC359_RS19355	COG2340	Cysteine-rich secretory protein family
BC359_RS19365	COG0693	protein deglycase activity
BC359_RS19370	COG1115	amino acid carrier protein
BC359_RS19380	COG1017	nitric oxide dioxygenase activity
BC359_RS19380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BC359_RS19385	COG1959	2 iron, 2 sulfur cluster binding
BC359_RS19390	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BC359_RS19400	COG0488	(ABC) transporter
BC359_RS19415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC359_RS19425	COG2356	endonuclease I
BC359_RS19440	COG1511	domain protein
BC359_RS19445	COG0433	COG0433 Predicted ATPase
BC359_RS19445	COG1674	ftsk spoiiie
BC359_RS19450	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC359_RS19455	COG5417	Belongs to the EsaB family
BC359_RS19460	COG4842	Belongs to the WXG100 family
BC359_RS19480	COG0513	Belongs to the DEAD box helicase family
BC359_RS19485	COG2205	protein histidine kinase activity
BC359_RS19485	COG0784	Response regulator, receiver
BC359_RS19490	COG2311	Membrane
BC359_RS19495	COG3852	Histidine kinase
BC359_RS19505	COG0598	Magnesium transport protein CorA
BC359_RS19515	COG1115	amino acid carrier protein
BC359_RS19525	COG2318	DinB family
BC359_RS19555	COG0693	protein deglycase activity
BC359_RS19560	COG0745	RESPONSE REGULATOR receiver
BC359_RS19565	COG5002	protein histidine kinase activity
BC359_RS19565	COG3850	Histidine kinase
BC359_RS19585	COG1876	peptidase activity
BC359_RS19595	COG2070	2-Nitropropane dioxygenase
BC359_RS19600	COG2706	6-phosphogluconolactonase activity
BC359_RS19605	COG0024	Methionine aminopeptidase
BC359_RS19610	COG3852	Histidine kinase
BC359_RS19615	COG1744	ABC transporter substrate-binding protein PnrA-like
BC359_RS19620	COG0166	Belongs to the GPI family
BC359_RS19625	COG1187	pseudouridine synthase activity
BC359_RS19630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BC359_RS19635	COG0581	inorganic phosphate transmembrane transporter activity
BC359_RS19640	COG0573	inorganic phosphate transmembrane transporter activity
BC359_RS19645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC359_RS19650	COG1132	(ABC) transporter
BC359_RS19655	COG1253	flavin adenine dinucleotide binding
BC359_RS19685	COG1404	Belongs to the peptidase S8 family
BC359_RS19745	COG1597	lipid kinase activity
BC359_RS19755	COG0154	amidase activity
BC359_RS19760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BC359_RS19770	COG4851	CamS sex pheromone cAM373 precursor
BC359_RS19775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BC359_RS19780	COG0210	DNA helicase
BC359_RS19785	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BC359_RS19790	COG0423	glycine-tRNA ligase activity
BC359_RS19795	COG4496	protein, YerC YecD
BC359_RS19800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BC359_RS19810	COG0151	Belongs to the GarS family
BC359_RS19815	COG0138	bifunctional purine biosynthesis protein purh
BC359_RS19820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BC359_RS19825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BC359_RS19830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BC359_RS19835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC359_RS19840	COG0047	phosphoribosylformylglycinamidine synthase activity
BC359_RS19845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC359_RS19850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BC359_RS19855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC359_RS19860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BC359_RS19865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC359_RS19905	COG2252	PERMEase
BC359_RS19910	COG0519	Catalyzes the synthesis of GMP from XMP
BC359_RS19910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BC359_RS19915	COG1305	Transglutaminase-like
BC359_RS19920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BC359_RS19925	COG0714	Associated with various cellular activities
BC359_RS19940	COG1733	regulation of RNA biosynthetic process
BC359_RS19950	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC359_RS19955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BC359_RS19965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BC359_RS19975	COG0300	oxidoreductase activity
BC359_RS19995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BC359_RS20000	COG1266	CAAX protease self-immunity
BC359_RS20010	COG0805	protein transport
BC359_RS20015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BC359_RS20020	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BC359_RS20025	COG0488	(ABC) transporter
BC359_RS20035	COG0456	acetyltransferase
BC359_RS20040	COG1214	PFAM Peptidase M22, glycoprotease
BC359_RS20045	COG0802	atpase or kinase
BC359_RS20135	COG2183	response to ionizing radiation
BC359_RS20140	COG2208	phosphoserine phosphatase activity
BC359_RS20145	COG1191	sigma factor activity
BC359_RS20155	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_RS20160	COG2208	phosphoserine phosphatase activity
BC359_RS20165	COG2172	sigma factor antagonist activity
BC359_RS20170	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_RS20175	COG1366	Belongs to the anti-sigma-factor antagonist family
BC359_RS20180	COG2337	Toxic component of a toxin-antitoxin (TA) module
BC359_RS20185	COG0864	Transcriptional regulator
BC359_RS20190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC359_RS20195	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BC359_RS20200	COG0736	holo-[acyl-carrier-protein] synthase activity
BC359_RS20205	COG0705	Rhomboid family
BC359_RS20210	COG4294	response to UV
BC359_RS20215	COG0513	Belongs to the DEAD box helicase family
BC359_RS20220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC359_RS20225	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC359_RS20235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BC359_RS20250	COG3842	ATPase activity
BC359_RS20260	COG3527	Alpha-acetolactate decarboxylase
BC359_RS20270	COG0246	Mannitol dehydrogenase
BC359_RS20275	COG3711	transcriptional antiterminator
BC359_RS20280	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC359_RS20280	COG2213	PTS system mannitol-specific
BC359_RS20290	COG1556	Lactate utilization protein
BC359_RS20295	COG1139	Iron-sulfur cluster binding protein
BC359_RS20300	COG0247	lactate metabolic process
BC359_RS20305	COG2186	Transcriptional regulator
BC359_RS20310	COG1620	l-lactate permease
BC359_RS20320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BC359_RS20325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC359_RS20330	COG4856	YbbR-like protein
BC359_RS20335	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC359_RS20340	COG5662	AntiSigma factor
BC359_RS20345	COG1595	DNA-templated transcription, initiation
BC359_RS20420	COG0726	polysaccharide deacetylase
BC359_RS20425	COG2194	sulfuric ester hydrolase activity
BC359_RS20435	COG0489	protein tyrosine kinase activity
BC359_RS20440	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC359_RS20465	COG3341	Caulimovirus viroplasmin
BC359_RS20465	COG0328	RNA-DNA hybrid ribonuclease activity
BC359_RS20490	COG1346	cytolysis
BC359_RS20605	COG1073	alpha beta
BC359_RS20610	COG5002	protein histidine kinase activity
BC359_RS20615	COG2197	response regulator
BC359_RS20690	COG0741	lytic transglycosylase activity
BC359_RS20690	COG0791	NLP P60 protein
BC359_RS20760	COG1376	ErfK ybiS ycfS ynhG family protein
BC359_RS20830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC359_RS20895	COG3344	reverse transcriptase
BC359_RS20910	COG5002	protein histidine kinase activity
BC359_RS20915	COG2002	toxin-antitoxin pair type II binding
BC359_RS20945	COG1725	Transcriptional regulator
BC359_RS20955	COG1380	Effector of murein hydrolase LrgA
BC359_RS20960	COG1346	cytolysis
BC359_RS20980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BC359_RS20985	COG0583	DNA-binding transcription factor activity