locus-tag	class	description
D9829_RS00025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9829_RS00045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9829_RS00050	COG0640	Transcriptional regulator
D9829_RS00055	COG0589	response to stress
D9829_RS00060	COG0640	Transcriptional regulator
D9829_RS00080	COG0395	ABC-type sugar transport system, permease component
D9829_RS00085	COG4209	transmembrane transport
D9829_RS00090	COG1653	transport
D9829_RS00095	COG2207	Transcriptional regulator
D9829_RS00095	COG0662	Cupin 2, conserved barrel domain protein
D9829_RS00100	COG5578	integral membrane protein
D9829_RS00110	COG3250	beta-galactosidase activity
D9829_RS00115	COG2207	Transcriptional regulator
D9829_RS00130	COG0583	DNA-binding transcription factor activity
D9829_RS00155	COG0300	oxidoreductase activity
D9829_RS00160	COG0667	Aldo Keto reductase
D9829_RS00180	COG0657	acetylesterase activity
D9829_RS00295	COG0582	viral genome integration into host DNA
D9829_RS00305	COG2076	Multidrug Resistance protein
D9829_RS00310	COG2076	Multidrug Resistance protein
D9829_RS00315	COG4846	Membrane protein involved in cytochrome C biogenesis
D9829_RS00320	COG2201	protein-glutamate methylesterase activity
D9829_RS00325	COG0785	Cytochrome C biogenesis protein
D9829_RS00335	COG1132	(ABC) transporter
D9829_RS00340	COG1132	(ABC) transporter
D9829_RS00345	COG0791	NLP P60 protein
D9829_RS00345	COG1388	LysM domain
D9829_RS00355	COG0840	transmembrane signaling receptor activity
D9829_RS00360	COG3763	UPF0154 protein
D9829_RS00370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9829_RS00380	COG4224	UPF0291 protein
D9829_RS00385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9829_RS00390	COG1388	LysM domain
D9829_RS00395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9829_RS00405	COG0693	protein deglycase activity
D9829_RS00410	COG0174	glutamine synthetase
D9829_RS00415	COG0789	Transcriptional regulator
D9829_RS00420	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9829_RS00425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9829_RS00430	COG0464	growth
D9829_RS00440	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9829_RS00445	COG1077	Cell shape determining protein MreB Mrl
D9829_RS00460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9829_RS00465	COG1131	(ABC) transporter
D9829_RS00470	COG4473	ABC transporter
D9829_RS00485	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9829_RS00490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9829_RS00495	COG1013	pyruvate-flavodoxin oxidoreductase activity
D9829_RS00500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D9829_RS00500	COG0674	pyruvate-flavodoxin oxidoreductase activity
D9829_RS00505	COG2359	stage V sporulation protein S
D9829_RS00510	COG1692	metallophosphoesterase
D9829_RS00515	COG1418	mRNA catabolic process
D9829_RS00520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D9829_RS00525	COG1546	Belongs to the CinA family
D9829_RS00525	COG1058	Belongs to the CinA family
D9829_RS00530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9829_RS00535	COG1426	Protein conserved in bacteria
D9829_RS00550	COG0300	oxidoreductase activity
D9829_RS00555	COG0612	Peptidase, M16
D9829_RS00560	COG0612	Peptidase, M16
D9829_RS00565	COG1079	Belongs to the binding-protein-dependent transport system permease family
D9829_RS00570	COG4603	Belongs to the binding-protein-dependent transport system permease family
D9829_RS00575	COG3845	ABC transporter
D9829_RS00580	COG1744	ABC transporter substrate-binding protein PnrA-like
D9829_RS00585	COG2188	Transcriptional regulator
D9829_RS00590	COG4980	gas vesicle protein
D9829_RS00590	COG1674	ftsk spoiiie
D9829_RS00600	COG0740	serine-type endopeptidase activity
D9829_RS00605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9829_RS00615	COG0527	aspartate kinase activity
D9829_RS00620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9829_RS00625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9829_RS00630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9829_RS00635	COG1873	PFAM PRC-barrel domain
D9829_RS00640	COG0612	Peptidase, M16
D9829_RS00645	COG0726	polysaccharide deacetylase
D9829_RS00650	COG1185	polyribonucleotide nucleotidyltransferase activity
D9829_RS00660	COG0196	riboflavin kinase activity
D9829_RS00665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9829_RS00670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9829_RS00675	COG1550	Protein conserved in bacteria
D9829_RS00685	COG1358	cellular component organization or biogenesis
D9829_RS00690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9829_RS00695	COG0195	Participates in both transcription termination and antitermination
D9829_RS00700	COG0779	Required for maturation of 30S ribosomal subunits
D9829_RS00705	COG2176	DNA-directed DNA polymerase activity
D9829_RS00715	COG0750	zinc metalloprotease
D9829_RS00720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9829_RS00725	COG4589	Belongs to the CDS family
D9829_RS00735	COG0233	cytoplasmic translational termination
D9829_RS00740	COG0528	UMP kinase activity
D9829_RS00765	COG1191	sigma factor activity
D9829_RS00770	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9829_RS00775	COG1776	CheC inhibitor of MCP methylation
D9829_RS00780	COG0835	chemotaxis
D9829_RS00785	COG2198	Histidine kinase
D9829_RS00785	COG0643	Histidine kinase
D9829_RS00790	COG2201	protein-glutamate methylesterase activity
D9829_RS00795	COG0455	bacterial-type flagellum organization
D9829_RS00800	COG1419	protein localization to endoplasmic reticulum
D9829_RS00805	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9829_RS00810	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9829_RS00815	COG1684	flagellar biosynthetic protein fliR
D9829_RS00820	COG1987	bacterial-type flagellum assembly
D9829_RS00825	COG1338	Plays a role in the flagellum-specific transport system
D9829_RS00830	COG3190	flagellar
D9829_RS00835	COG2201	protein-glutamate methylesterase activity
D9829_RS00840	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9829_RS00840	COG1776	CheC inhibitor of MCP methylation
D9829_RS00845	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9829_RS00850	COG1580	Controls the rotational direction of flagella during chemotaxis
D9829_RS00855	COG1582	Flagellar protein (FlbD)
D9829_RS00860	COG4786	Flagellar basal body rod
D9829_RS00870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9829_RS00885	COG2882	bacterial-type flagellum organization
D9829_RS00890	COG1157	protein secretion by the type III secretion system
D9829_RS00895	COG1317	bacterial-type flagellum organization
D9829_RS00900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9829_RS00905	COG1766	The M ring may be actively involved in energy transduction
D9829_RS00910	COG1677	Flagellar hook-basal body complex protein FliE
D9829_RS00915	COG1558	bacterial-type flagellum-dependent cell motility
D9829_RS00920	COG1815	bacterial-type flagellum-dependent cell motility
D9829_RS00925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9829_RS00930	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9829_RS00940	COG4974	Belongs to the 'phage' integrase family
D9829_RS00945	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9829_RS00950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9829_RS00955	COG0758	DNA mediated transformation
D9829_RS00960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9829_RS00970	COG2257	FlhB HrpN YscU SpaS Family
D9829_RS01005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9829_RS01015	COG1837	Belongs to the UPF0109 family
D9829_RS01025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9829_RS01030	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9829_RS01035	COG0552	protein localization to endoplasmic reticulum
D9829_RS01040	COG1196	nuclear chromosome segregation
D9829_RS01045	COG0571	ribonuclease III activity
D9829_RS01050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9829_RS01055	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS01060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9829_RS01065	COG0416	fatty acid biosynthetic process
D9829_RS01070	COG1349	DNA-binding transcription factor activity
D9829_RS01075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9829_RS01085	COG1461	Dihydroxyacetone kinase
D9829_RS01090	COG1302	Protein conserved in bacteria
D9829_RS01095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9829_RS01105	COG1564	THIamine pyrophosphokinase
D9829_RS01110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9829_RS01115	COG1162	GTPase activity
D9829_RS01120	COG2815	serine threonine protein kinase
D9829_RS01120	COG0515	serine threonine protein kinase
D9829_RS01125	COG0631	protein serine/threonine phosphatase activity
D9829_RS01135	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9829_RS01135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9829_RS01140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9829_RS01145	COG0242	peptide deformylase activity
D9829_RS01150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9829_RS01155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9829_RS01160	COG0194	GDP metabolic process
D9829_RS01165	COG2052	Domain of unknown function (DUF370)
D9829_RS01170	COG1561	YicC-like family, N-terminal region
D9829_RS01175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9829_RS01195	COG0167	dihydroorotate dehydrogenase activity
D9829_RS01200	COG0543	2 iron, 2 sulfur cluster binding
D9829_RS01215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9829_RS01220	COG0540	Belongs to the ATCase OTCase family
D9829_RS01230	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9829_RS01235	COG0564	pseudouridine synthase activity
D9829_RS01240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9829_RS01250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9829_RS01255	COG3599	regulation of cell shape
D9829_RS01265	COG0762	integral membrane protein
D9829_RS01270	COG1799	cell septum assembly
D9829_RS01275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9829_RS01280	COG1496	oxidoreductase activity
D9829_RS01285	COG1873	PFAM PRC-barrel domain
D9829_RS01290	COG1191	sigma factor activity
D9829_RS01295	COG1191	sigma factor activity
D9829_RS01315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9829_RS01320	COG0849	cell division
D9829_RS01325	COG3856	small basic protein
D9829_RS01330	COG3879	Bacterial protein of unknown function (DUF881)
D9829_RS01335	COG3879	Bacterial protein of unknown function (DUF881)
D9829_RS01340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9829_RS01345	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9829_RS01355	COG0772	Belongs to the SEDS family
D9829_RS01360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9829_RS01365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9829_RS01375	COG0768	penicillin binding
D9829_RS01380	COG0768	penicillin binding
D9829_RS01385	COG4839	cell division protein FtsL
D9829_RS01390	COG0275	rRNA processing
D9829_RS01395	COG2001	Belongs to the MraZ family
D9829_RS01400	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9829_RS01410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9829_RS01415	COG0454	-acetyltransferase
D9829_RS01425	COG1024	Enoyl-CoA hydratase
D9829_RS01430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9829_RS01435	COG1399	metal-binding, possibly nucleic acid-binding protein
D9829_RS01440	COG1323	Belongs to the UPF0348 family
D9829_RS01445	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9829_RS01450	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9829_RS01455	COG3314	Sporulation integral membrane protein YlbJ
D9829_RS01460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9829_RS01465	COG0742	ribosomal rna small subunit methyltransferase
D9829_RS01480	COG4471	UPF0298 protein
D9829_RS01485	COG3679	Belongs to the UPF0342 family
D9829_RS01505	COG2340	Cysteine-rich secretory protein family
D9829_RS01525	COG0628	permease
D9829_RS01540	COG3336	cytochrome c oxidase
D9829_RS01565	COG0109	protoheme IX farnesyltransferase activity
D9829_RS01570	COG1612	heme a metabolic process
D9829_RS01575	COG0772	Belongs to the SEDS family
D9829_RS01580	COG4838	Belongs to the UPF0358 family
D9829_RS01585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9829_RS01590	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9829_RS01605	COG4896	Protein conserved in bacteria
D9829_RS01625	COG1217	gtp-binding protein TYPA
D9829_RS01640	COG0483	inositol monophosphate 1-phosphatase activity
D9829_RS01650	COG4493	Belongs to the UPF0637 family
D9829_RS01655	COG4476	Belongs to the UPF0223 family
D9829_RS01665	COG1982	Orn Lys Arg decarboxylase major
D9829_RS01685	COG0726	polysaccharide deacetylase
D9829_RS01695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS01705	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9829_RS01710	COG0022	dehydrogenase e1 component
D9829_RS01720	COG0497	DNA recombination
D9829_RS01730	COG0242	peptide deformylase activity
D9829_RS01740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9829_RS01745	COG0569	domain protein
D9829_RS01755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS01760	COG0450	alkyl hydroperoxide reductase
D9829_RS01765	COG1473	amidohydrolase
D9829_RS01770	COG2171	N-acyltransferase activity
D9829_RS01775	COG0583	DNA-binding transcription factor activity
D9829_RS01780	COG0517	IMP dehydrogenase activity
D9829_RS01785	COG4703	Protein of unknown function (DUF1797)
D9829_RS01790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS01795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D9829_RS01810	COG2200	EAL domain
D9829_RS01815	COG1408	metallophosphoesterase
D9829_RS01820	COG5001	Diguanylate cyclase
D9829_RS01820	COG3300	MHYT domain
D9829_RS01825	COG1376	ErfK ybiS ycfS ynhG family protein
D9829_RS01835	COG0436	Aminotransferase
D9829_RS01840	COG2084	Dehydrogenase
D9829_RS01850	COG0456	acetyltransferase
D9829_RS01860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS01870	COG4873	Protein conserved in bacteria
D9829_RS01875	COG0702	epimerase
D9829_RS01890	COG3949	Membrane
D9829_RS01895	COG0542	response to heat
D9829_RS01905	COG1846	Transcriptional regulator
D9829_RS01910	COG1704	LemA family
D9829_RS01925	COG5577	PFAM Coat F domain
D9829_RS01935	COG2223	nitrite transmembrane transporter activity
D9829_RS01950	COG0644	oxidoreductase
D9829_RS01955	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9829_RS01970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9829_RS01980	COG3594	Acyltransferase
D9829_RS01995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9829_RS02010	COG1191	sigma factor activity
D9829_RS02015	COG0861	Integral membrane protein TerC family
D9829_RS02025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9829_RS02030	COG1757	Na H antiporter
D9829_RS02035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D9829_RS02045	COG0395	ABC-type sugar transport system, permease component
D9829_RS02050	COG1175	transmembrane transport
D9829_RS02070	COG0584	glycerophosphoryl diester phosphodiesterase
D9829_RS02075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9829_RS02105	COG1876	peptidase activity
D9829_RS02110	COG4191	Histidine kinase
D9829_RS02115	COG1115	amino acid carrier protein
D9829_RS02125	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS02130	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS02135	COG0535	radical SAM domain protein
D9829_RS02140	COG0710	3-dehydroquinate dehydratase activity
D9829_RS02145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9829_RS02155	COG4607	ABC-type enterochelin transport system periplasmic component
D9829_RS02165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9829_RS02175	COG1842	Phage shock protein A
D9829_RS02180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9829_RS02190	COG0628	permease
D9829_RS02195	COG2323	membrane
D9829_RS02205	COG2233	PERMEase
D9829_RS02210	COG1309	transcriptional regulator
D9829_RS02215	COG1917	Cupin 2, conserved barrel domain protein
D9829_RS02225	COG4753	response regulator
D9829_RS02225	COG2207	Transcriptional regulator
D9829_RS02230	COG2972	Histidine kinase
D9829_RS02245	COG1472	Belongs to the glycosyl hydrolase 3 family
D9829_RS02260	COG1501	Belongs to the glycosyl hydrolase 31 family
D9829_RS02265	COG1653	transport
D9829_RS02270	COG0395	ABC-type sugar transport system, permease component
D9829_RS02275	COG4209	transmembrane transport
D9829_RS02280	COG0745	RESPONSE REGULATOR receiver
D9829_RS02325	COG2358	TRAP transporter, solute receptor (TAXI family
D9829_RS02330	COG2382	esterase
D9829_RS02335	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9829_RS02340	COG2153	protein acetylation
D9829_RS02350	COG0210	DNA helicase
D9829_RS02375	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS02390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9829_RS02490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9829_RS02530	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS02570	COG0569	domain protein
D9829_RS02570	COG0475	glutathione-regulated potassium exporter activity
D9829_RS02575	COG2239	Acts as a magnesium transporter
D9829_RS02580	COG0564	pseudouridine synthase activity
D9829_RS02590	COG2357	RelA SpoT domain protein
D9829_RS02600	COG4116	CYTH
D9829_RS02605	COG0741	lytic transglycosylase activity
D9829_RS02610	COG2346	COG2346, Truncated hemoglobins
D9829_RS02615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9829_RS02620	COG1164	Oligoendopeptidase f
D9829_RS02625	COG4469	Competence protein
D9829_RS02630	COG4862	establishment of competence for transformation
D9829_RS02635	COG1393	Belongs to the ArsC family
D9829_RS02640	COG0456	acetyltransferase
D9829_RS02655	COG4608	Belongs to the ABC transporter superfamily
D9829_RS02660	COG0444	Belongs to the ABC transporter superfamily
D9829_RS02665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9829_RS02670	COG0601	transmembrane transport
D9829_RS02675	COG4166	transmembrane transport
D9829_RS02685	COG0180	Tryptophanyl-tRNA synthetase
D9829_RS02695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9829_RS02700	COG0601	transmembrane transport
D9829_RS02710	COG4608	Belongs to the ABC transporter superfamily
D9829_RS02715	COG0444	Belongs to the ABC transporter superfamily
D9829_RS02720	COG5504	Zn-dependent protease
D9829_RS02725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9829_RS02730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9829_RS02745	COG1744	ABC transporter substrate-binding protein PnrA-like
D9829_RS02755	COG2267	carboxylic ester hydrolase activity
D9829_RS02785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9829_RS02795	COG0505	Belongs to the CarA family
D9829_RS02810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D9829_RS02815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9829_RS02830	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9829_RS02835	COG0303	'Molybdopterin
D9829_RS02840	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
D9829_RS02845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9829_RS02850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9829_RS02855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9829_RS02860	COG0535	radical SAM domain protein
D9829_RS02865	COG2223	nitrite transmembrane transporter activity
D9829_RS02870	COG2151	metal-sulfur cluster biosynthetic enzyme
D9829_RS02875	COG1073	alpha beta
D9829_RS02880	COG0561	phosphatase activity
D9829_RS02895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS02900	COG1307	EDD domain protein, DegV family
D9829_RS02910	COG2996	Protein conserved in bacteria
D9829_RS02915	COG1666	GTP binding
D9829_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS02925	COG1609	Transcriptional regulator
D9829_RS02930	COG0366	Alpha amylase catalytic
D9829_RS02930	COG1874	Beta-galactosidase
D9829_RS02935	COG3833	ABC-type maltose transport systems, permease component
D9829_RS02940	COG1175	transmembrane transport
D9829_RS02945	COG2182	Extracellular solute-binding protein
D9829_RS02955	COG0367	asparagine synthase
D9829_RS02975	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9829_RS02980	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS03020	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9829_RS03040	COG0398	Pfam SNARE associated Golgi protein
D9829_RS03050	COG1506	peptidase
D9829_RS03050	COG4946	Tricorn protease homolog
D9829_RS03050	COG0823	Involved in the tonB-independent uptake of proteins
D9829_RS03060	COG4903	ComK protein
D9829_RS03070	COG0501	Belongs to the peptidase M48B family
D9829_RS03090	COG1122	ATPase activity
D9829_RS03105	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS03110	COG0095	Lipoate-protein ligase
D9829_RS03115	COG1234	tRNA 3'-trailer cleavage
D9829_RS03125	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9829_RS03130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9829_RS03135	COG2329	Antibiotic biosynthesis monooxygenase
D9829_RS03140	COG3069	C4-dicarboxylate transmembrane transporter activity
D9829_RS03145	COG1473	amidohydrolase
D9829_RS03160	COG4473	ABC transporter
D9829_RS03165	COG1131	(ABC) transporter
D9829_RS03170	COG0537	adenosine 5'-monophosphoramidase activity
D9829_RS03175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9829_RS03190	COG1846	Transcriptional regulator
D9829_RS03215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9829_RS03225	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9829_RS03230	COG4717	serine-type aminopeptidase activity
D9829_RS03235	COG0420	3'-5' exonuclease activity
D9829_RS03245	COG1668	transmembrane transport
D9829_RS03250	COG4152	abc transporter atp-binding protein
D9829_RS03260	COG1024	Enoyl-CoA hydratase
D9829_RS03265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9829_RS03270	COG0561	phosphatase activity
D9829_RS03280	COG3679	Belongs to the UPF0342 family
D9829_RS03290	COG0189	ligase activity
D9829_RS03295	COG0189	ligase activity
D9829_RS03300	COG0189	ligase activity
D9829_RS03310	COG1937	Protein conserved in bacteria
D9829_RS03315	COG2508	Transcriptional regulator
D9829_RS03320	COG3842	ATPase activity
D9829_RS03335	COG0114	fumarate hydratase activity
D9829_RS03350	COG1595	DNA-templated transcription, initiation
D9829_RS03355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9829_RS03365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9829_RS03370	COG0589	response to stress
D9829_RS03380	COG3859	Proton-coupled thiamine transporter YuaJ
D9829_RS03385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9829_RS03390	COG3852	Histidine kinase
D9829_RS03400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS03405	COG1253	flavin adenine dinucleotide binding
D9829_RS03430	COG2719	SpoVR family
D9829_RS03440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9829_RS03445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9829_RS03445	COG3153	acetyltransferase
D9829_RS03450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9829_RS03455	COG3118	belongs to the thioredoxin family
D9829_RS03465	COG0564	pseudouridine synthase activity
D9829_RS03470	COG2261	transglycosylase associated protein
D9829_RS03475	COG1392	Phosphate transport regulator
D9829_RS03480	COG0306	phosphate transporter
D9829_RS03490	COG2252	PERMEase
D9829_RS03495	COG5002	protein histidine kinase activity
D9829_RS03500	COG0745	RESPONSE REGULATOR receiver
D9829_RS03525	COG5002	protein histidine kinase activity
D9829_RS03535	COG0628	permease
D9829_RS03540	COG2094	Belongs to the DNA glycosylase MPG family
D9829_RS03555	COG1307	EDD domain protein, DegV family
D9829_RS03600	COG0673	inositol 2-dehydrogenase activity
D9829_RS03605	COG0673	inositol 2-dehydrogenase activity
D9829_RS03625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9829_RS03640	COG1904	glucuronate isomerase
D9829_RS03650	COG0833	amino acid
D9829_RS03685	COG0406	alpha-ribazole phosphatase activity
D9829_RS03695	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9829_RS03700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS03705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS03710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9829_RS03715	COG0628	permease
D9829_RS03725	COG0726	polysaccharide deacetylase
D9829_RS03730	COG0667	Aldo Keto reductase
D9829_RS03735	COG1070	Carbohydrate kinase
D9829_RS03740	COG2115	Belongs to the xylose isomerase family
D9829_RS03750	COG5578	integral membrane protein
D9829_RS03755	COG0395	ABC-type sugar transport system, permease component
D9829_RS03770	COG4753	response regulator
D9829_RS03770	COG2207	Transcriptional regulator
D9829_RS03775	COG2972	Histidine kinase
D9829_RS03785	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS03790	COG1312	Catalyzes the dehydration of D-mannonate
D9829_RS03795	COG1802	Transcriptional regulator
D9829_RS03805	COG0673	inositol 2-dehydrogenase activity
D9829_RS03830	COG0395	ABC-type sugar transport system, permease component
D9829_RS03835	COG4209	transmembrane transport
D9829_RS03850	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D9829_RS03865	COG0673	inositol 2-dehydrogenase activity
D9829_RS03875	COG0673	inositol 2-dehydrogenase activity
D9829_RS03880	COG1115	amino acid carrier protein
D9829_RS03885	COG1064	alcohol dehydrogenase
D9829_RS03890	COG0789	Transcriptional regulator
D9829_RS03900	COG4221	oxidoreductase activity
D9829_RS03910	COG2814	Major facilitator Superfamily
D9829_RS03940	COG2718	Belongs to the UPF0229 family
D9829_RS03945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9829_RS03960	COG2010	Cytochrome c
D9829_RS03970	COG2766	serine protein kinase
D9829_RS03975	COG0778	Nitroreductase
D9829_RS03980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9829_RS03990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9829_RS03995	COG3382	B3 4 domain protein
D9829_RS04005	COG4948	Mandelate Racemase Muconate Lactonizing
D9829_RS04015	COG0800	Aldolase
D9829_RS04020	COG3250	beta-galactosidase activity
D9829_RS04025	COG0395	ABC-type sugar transport system, permease component
D9829_RS04040	COG1414	Transcriptional regulator
D9829_RS04050	COG1482	cell wall glycoprotein biosynthetic process
D9829_RS04055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9829_RS04055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS04055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9829_RS04060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS04060	COG3711	transcriptional antiterminator
D9829_RS04190	COG0735	belongs to the Fur family
D9829_RS04195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9829_RS04215	COG4555	ABC transporter
D9829_RS04220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9829_RS04225	COG0070	glutamate synthase
D9829_RS04225	COG0069	glutamate synthase activity
D9829_RS04225	COG0067	glutamate synthase
D9829_RS04230	COG4129	membrane
D9829_RS04235	COG1132	(ABC) transporter
D9829_RS04240	COG3557	Belongs to the UPF0374 family
D9829_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS04265	COG1194	a g-specific adenine glycosylase
D9829_RS04270	COG1988	membrane-bound metal-dependent
D9829_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS04300	COG1090	epimerase
D9829_RS04315	COG2814	Major facilitator Superfamily
D9829_RS04325	COG0460	homoserine dehydrogenase
D9829_RS04330	COG1132	(ABC) transporter
D9829_RS04335	COG1132	(ABC) transporter
D9829_RS04355	COG2318	DinB family
D9829_RS04360	COG0183	Belongs to the thiolase family
D9829_RS04365	COG0697	spore germination
D9829_RS04375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9829_RS04375	COG1587	Uroporphyrinogen-III synthase
D9829_RS04380	COG2146	nitrite reductase [NAD(P)H] activity
D9829_RS04385	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9829_RS04430	COG2814	Major facilitator Superfamily
D9829_RS04440	COG2116	formate transmembrane transporter activity
D9829_RS04470	COG0489	protein tyrosine kinase activity
D9829_RS04475	COG0437	4 iron, 4 sulfur cluster binding
D9829_RS04480	COG0243	molybdopterin cofactor binding
D9829_RS04490	COG0604	alcohol dehydrogenase
D9829_RS04495	COG3610	response to peptide
D9829_RS04510	COG2814	Major facilitator Superfamily
D9829_RS04520	COG4187	Peptidase family M20/M25/M40
D9829_RS04525	COG1960	acyl-CoA dehydrogenase activity
D9829_RS04540	COG0765	amino acid transport
D9829_RS04555	COG5002	protein histidine kinase activity
D9829_RS04560	COG0166	Belongs to the GPI family
D9829_RS04565	COG4821	SIS domain
D9829_RS04570	COG2188	Transcriptional regulator
D9829_RS04575	COG0363	glucosamine-6-phosphate deaminase activity
D9829_RS04580	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9829_RS04595	COG1272	protein, Hemolysin III
D9829_RS04605	COG0789	Transcriptional regulator
D9829_RS04615	COG0004	ammonium transporteR
D9829_RS04650	COG2217	Heavy metal translocating P-type atpase
D9829_RS04660	COG2151	metal-sulfur cluster biosynthetic enzyme
D9829_RS04670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9829_RS04675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9829_RS04680	COG0693	protein deglycase activity
D9829_RS04680	COG0753	catalase activity
D9829_RS04700	COG1966	Carbon starvation protein
D9829_RS04705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9829_RS04755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9829_RS04760	COG0494	nUDIX hydrolase
D9829_RS04770	COG0778	Nitroreductase
D9829_RS04790	COG0534	Mate efflux family protein
D9829_RS04795	COG1253	flavin adenine dinucleotide binding
D9829_RS04800	COG2112	serine threonine protein kinase
D9829_RS04805	COG0861	Integral membrane protein TerC family
D9829_RS04815	COG4326	sporulation control protein
D9829_RS04850	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS04850	COG1454	alcohol dehydrogenase
D9829_RS04855	COG1968	undecaprenyl-diphosphatase activity
D9829_RS04860	COG4086	secreted protein
D9829_RS04870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9829_RS04875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9829_RS04880	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS04885	COG3829	transcription factor binding
D9829_RS04890	COG1760	l-serine dehydratase
D9829_RS04895	COG1760	l-serine dehydratase
D9829_RS04920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9829_RS04925	COG4990	cell redox homeostasis
D9829_RS04940	COG1595	DNA-templated transcription, initiation
D9829_RS04965	COG1473	amidohydrolase
D9829_RS04995	COG2096	Adenosyltransferase
D9829_RS05005	COG0406	alpha-ribazole phosphatase activity
D9829_RS05010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D9829_RS05015	COG1492	cobalamin metabolic process
D9829_RS05020	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
D9829_RS05025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9829_RS05030	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D9829_RS05035	COG1120	ATPase activity
D9829_RS05040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS05045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9829_RS05050	COG3011	Protein conserved in bacteria
D9829_RS05060	COG1268	BioY protein
D9829_RS05065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9829_RS05075	COG2040	homocysteine
D9829_RS05080	COG0833	amino acid
D9829_RS05085	COG1126	abc transporter atp-binding protein
D9829_RS05090	COG0765	amino acid transport
D9829_RS05095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9829_RS05100	COG1063	alcohol dehydrogenase
D9829_RS05105	COG3507	Belongs to the glycosyl hydrolase 43 family
D9829_RS05110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9829_RS05125	COG1653	transport
D9829_RS05130	COG0395	ABC-type sugar transport system, permease component
D9829_RS05135	COG4209	transmembrane transport
D9829_RS05145	COG5578	integral membrane protein
D9829_RS05150	COG0561	phosphatase activity
D9829_RS05165	COG4807	Protein conserved in bacteria
D9829_RS05195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9829_RS05200	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9829_RS05220	COG0405	Gamma-glutamyltransferase
D9829_RS05235	COG2364	Membrane
D9829_RS05240	COG0387	Pfam Sodium calcium exchanger
D9829_RS05245	COG1765	OsmC-like protein
D9829_RS05250	COG0477	Major facilitator Superfamily
D9829_RS05255	COG2217	Heavy metal translocating P-type atpase
D9829_RS05260	COG4682	membrane
D9829_RS05265	COG1295	ribonuclease BN
D9829_RS05275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9829_RS05280	COG4840	Belongs to the UPF0435 family
D9829_RS05285	COG0024	Methionine aminopeptidase
D9829_RS05290	COG0693	protein deglycase activity
D9829_RS05320	COG1360	Flagellar Motor Protein
D9829_RS05325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9829_RS05330	COG1846	Transcriptional regulator
D9829_RS05335	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9829_RS05340	COG0561	phosphatase activity
D9829_RS05345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9829_RS05355	COG0450	alkyl hydroperoxide reductase
D9829_RS05375	COG0747	negative chemotaxis
D9829_RS05380	COG2323	membrane
D9829_RS05385	COG0697	spore germination
D9829_RS05400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS05405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9829_RS05405	COG0551	DNA topoisomerase type I activity
D9829_RS05420	COG2309	aminopeptidase activity
D9829_RS05425	COG1254	Belongs to the acylphosphatase family
D9829_RS05430	COG1970	mechanosensitive ion channel activity
D9829_RS05445	COG0598	Magnesium transport protein CorA
D9829_RS05465	COG0667	Aldo Keto reductase
D9829_RS05480	COG2244	polysaccharide biosynthetic process
D9829_RS05490	COG2197	response regulator
D9829_RS05495	COG4585	Histidine kinase
D9829_RS05515	COG2340	Cysteine-rich secretory protein family
D9829_RS05525	COG2323	membrane
D9829_RS05530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9829_RS05545	COG0154	amidase activity
D9829_RS05550	COG0513	Belongs to the DEAD box helicase family
D9829_RS05565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D9829_RS05565	COG2199	diguanylate cyclase activity
D9829_RS05570	COG5002	protein histidine kinase activity
D9829_RS05595	COG1132	(ABC) transporter
D9829_RS05630	COG1696	Membrane protein involved in D-alanine export
D9829_RS05655	COG0438	transferase activity, transferring glycosyl groups
D9829_RS05660	COG1216	Glycosyl transferase, family 2
D9829_RS05680	COG1396	sequence-specific DNA binding
D9829_RS05685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9829_RS05690	COG0110	maltose O-acetyltransferase activity
D9829_RS05695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9829_RS05700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9829_RS05710	COG0463	Glycosyl transferase, family 2
D9829_RS05715	COG0438	transferase activity, transferring glycosyl groups
D9829_RS05720	COG1216	Glycosyl transferase, family 2
D9829_RS05725	COG0438	transferase activity, transferring glycosyl groups
D9829_RS05730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9829_RS05735	COG1086	Polysaccharide biosynthesis protein
D9829_RS05740	COG0489	protein tyrosine kinase activity
D9829_RS05745	COG3944	biosynthesis protein
D9829_RS05750	COG1132	(ABC) transporter
D9829_RS05790	COG2832	Protein of unknown function (DUF454)
D9829_RS05800	COG1732	Glycine betaine
D9829_RS05810	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9829_RS05815	COG0582	viral genome integration into host DNA
D9829_RS05820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9829_RS05825	COG1253	flavin adenine dinucleotide binding
D9829_RS05830	COG2234	aminopeptidase activity
D9829_RS05835	COG1668	transmembrane transport
D9829_RS05840	COG4555	ABC transporter
D9829_RS05845	COG3279	Response regulator of the LytR AlgR family
D9829_RS05855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9829_RS05865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS05865	COG1263	PTS System
D9829_RS05890	COG2149	membrane
D9829_RS05895	COG0730	response to heat
D9829_RS05900	COG0425	Belongs to the sulfur carrier protein TusA family
D9829_RS05905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS05905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9829_RS05910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9829_RS05910	COG0425	Belongs to the sulfur carrier protein TusA family
D9829_RS05920	COG2210	Belongs to the sulfur carrier protein TusA family
D9829_RS05925	COG1937	Protein conserved in bacteria
D9829_RS05930	COG2814	Major facilitator Superfamily
D9829_RS05935	COG1309	transcriptional regulator
D9829_RS05940	COG0840	transmembrane signaling receptor activity
D9829_RS05940	COG5278	phosphoserine phosphatase activity
D9829_RS05945	COG3540	Alkaline phosphatase
D9829_RS05950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9829_RS05960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9829_RS05965	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS05970	COG0506	proline dehydrogenase activity
D9829_RS05975	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9829_RS06000	COG1609	Transcriptional regulator
D9829_RS06015	COG1595	DNA-templated transcription, initiation
D9829_RS06020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9829_RS06035	COG0514	ATP-dependent DNA helicase (RecQ)
D9829_RS06040	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9829_RS06045	COG1335	isochorismatase
D9829_RS06050	COG1597	lipid kinase activity
D9829_RS06055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9829_RS06060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9829_RS06065	COG0154	amidase activity
D9829_RS06070	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9829_RS06075	COG5506	Protein of unknown function (DUF1694)
D9829_RS06080	COG2224	Isocitrate lyase
D9829_RS06085	COG1349	DNA-binding transcription factor activity
D9829_RS06090	COG1942	4-Oxalocrotonate Tautomerase
D9829_RS06095	COG2814	Major facilitator Superfamily
D9829_RS06100	COG0191	fructose-bisphosphate aldolase activity
D9829_RS06105	COG1082	Xylose isomerase domain protein TIM barrel
D9829_RS06110	COG1082	Xylose isomerase domain protein TIM barrel
D9829_RS06115	COG0673	inositol 2-dehydrogenase activity
D9829_RS06120	COG2814	Major facilitator Superfamily
D9829_RS06125	COG1082	Xylose isomerase domain protein TIM barrel
D9829_RS06130	COG3962	Belongs to the TPP enzyme family
D9829_RS06135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS06140	COG3718	enzyme involved in inositol metabolism
D9829_RS06145	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS06150	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS06160	COG4851	CamS sex pheromone cAM373 precursor
D9829_RS06165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9829_RS06170	COG0210	DNA helicase
D9829_RS06175	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9829_RS06180	COG4496	protein, YerC YecD
D9829_RS06185	COG1470	cell adhesion involved in biofilm formation
D9829_RS06190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9829_RS06200	COG0151	Belongs to the GarS family
D9829_RS06205	COG0138	bifunctional purine biosynthesis protein purh
D9829_RS06210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9829_RS06215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9829_RS06220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9829_RS06225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9829_RS06230	COG0047	phosphoribosylformylglycinamidine synthase activity
D9829_RS06235	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9829_RS06240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9829_RS06245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9829_RS06250	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9829_RS06255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9829_RS06265	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9829_RS06290	COG2190	(PTS) system
D9829_RS06290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS06290	COG1263	PTS System
D9829_RS06295	COG3711	transcriptional antiterminator
D9829_RS06300	COG2252	PERMEase
D9829_RS06305	COG0519	Catalyzes the synthesis of GMP from XMP
D9829_RS06305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9829_RS06310	COG1305	Transglutaminase-like
D9829_RS06315	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9829_RS06320	COG0714	Associated with various cellular activities
D9829_RS06340	COG4214	carbohydrate transport
D9829_RS06350	COG4213	ABC transporter substrate-binding protein
D9829_RS06355	COG4753	response regulator
D9829_RS06355	COG2207	Transcriptional regulator
D9829_RS06360	COG2972	Histidine kinase
D9829_RS06370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9829_RS06380	COG0459	protein refolding
D9829_RS06390	COG1266	CAAX protease self-immunity
D9829_RS06400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9829_RS06410	COG0488	(ABC) transporter
D9829_RS06420	COG0456	acetyltransferase
D9829_RS06425	COG1214	PFAM Peptidase M22, glycoprotease
D9829_RS06430	COG0802	atpase or kinase
D9829_RS06520	COG3091	SprT-like family
D9829_RS06530	COG2183	response to ionizing radiation
D9829_RS06535	COG2208	phosphoserine phosphatase activity
D9829_RS06540	COG1191	sigma factor activity
D9829_RS06545	COG2172	sigma factor antagonist activity
D9829_RS06550	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS06555	COG2208	phosphoserine phosphatase activity
D9829_RS06560	COG2172	sigma factor antagonist activity
D9829_RS06565	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS06570	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS06575	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9829_RS06580	COG0864	Transcriptional regulator
D9829_RS06590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9829_RS06595	COG0736	holo-[acyl-carrier-protein] synthase activity
D9829_RS06600	COG0705	Rhomboid family
D9829_RS06605	COG3428	Bacterial PH domain
D9829_RS06610	COG3402	PFAM membrane-flanked domain
D9829_RS06615	COG4294	response to UV
D9829_RS06620	COG0513	Belongs to the DEAD box helicase family
D9829_RS06625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9829_RS06630	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9829_RS06635	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D9829_RS06645	COG2239	Acts as a magnesium transporter
D9829_RS06650	COG0772	Belongs to the SEDS family
D9829_RS06655	COG0668	transmembrane transport
D9829_RS06660	COG1742	UPF0060 membrane protein
D9829_RS06665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9829_RS06670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9829_RS06675	COG4856	YbbR-like protein
D9829_RS06680	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9829_RS06685	COG5662	AntiSigma factor
D9829_RS06690	COG1595	DNA-templated transcription, initiation
D9829_RS06770	COG0726	polysaccharide deacetylase
D9829_RS06775	COG2194	sulfuric ester hydrolase activity
D9829_RS06785	COG0489	protein tyrosine kinase activity
D9829_RS06790	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9829_RS06800	COG0584	glycerophosphoryl diester phosphodiesterase
D9829_RS06805	COG1793	dna ligase
D9829_RS06815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9829_RS06820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9829_RS06830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9829_RS06835	COG1122	ATPase activity
D9829_RS06840	COG1122	ATPase activity
D9829_RS06845	COG0203	ribosomal protein L17
D9829_RS06850	COG0202	RNA polymerase activity
D9829_RS06855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9829_RS06865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9829_RS06870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9829_RS06875	COG0024	Methionine aminopeptidase
D9829_RS06880	COG0563	adenylate kinase activity
D9829_RS06885	COG0201	protein transport
D9829_RS06895	COG1841	ribosomal large subunit assembly
D9829_RS06900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9829_RS06930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D9829_RS06940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9829_RS06945	COG0255	Belongs to the universal ribosomal protein uL29 family
D9829_RS06950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9829_RS06955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9829_RS06960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9829_RS06970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9829_RS06980	COG0088	Forms part of the polypeptide exit tunnel
D9829_RS06985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9829_RS06990	COG0051	transcription antitermination factor activity, RNA binding
D9829_RS07000	COG0529	Catalyzes the synthesis of activated sulfate
D9829_RS07010	COG0306	phosphate transporter
D9829_RS07015	COG0175	sulfate reduction
D9829_RS07035	COG0049	tRNA binding
D9829_RS07040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9829_RS07045	COG1358	cellular component organization or biogenesis
D9829_RS07050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9829_RS07055	COG0085	RNA polymerase activity
D9829_RS07060	COG2813	Specifically methylates the guanine in position
D9829_RS07065	COG0222	ribosome binding
D9829_RS07070	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9829_RS07075	COG0081	regulation of translation
D9829_RS07085	COG0250	Participates in transcription elongation, termination and antitermination
D9829_RS07095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9829_RS07110	COG3688	RNA-binding protein containing a PIN domain
D9829_RS07115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9829_RS07125	COG0215	cysteine-tRNA ligase activity
D9829_RS07130	COG1045	serine acetyltransferase
D9829_RS07135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9829_RS07140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9829_RS07145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9829_RS07150	COG4956	integral membrane protein (PIN domain superfamily)
D9829_RS07155	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9829_RS07160	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9829_RS07165	COG0542	response to heat
D9829_RS07170	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9829_RS07175	COG3880	PFAM UvrB UvrC protein
D9829_RS07265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9829_RS07270	COG1396	sequence-specific DNA binding
D9829_RS07275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9829_RS07280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9829_RS07285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9829_RS07290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9829_RS07295	COG0512	Glutamine amidotransferase of anthranilate synthase
D9829_RS07300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9829_RS07305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9829_RS07310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9829_RS07315	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9829_RS07320	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9829_RS07325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9829_RS07335	COG0515	serine threonine protein kinase
D9829_RS07340	COG2304	oxidoreductase activity
D9829_RS07345	COG2208	phosphoserine phosphatase activity
D9829_RS07360	COG1098	S1 RNA binding domain
D9829_RS07365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9829_RS07380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9829_RS07385	COG3956	TIGRFAM MazG family protein
D9829_RS07390	COG2244	polysaccharide biosynthetic process
D9829_RS07395	COG2002	toxin-antitoxin pair type II binding
D9829_RS07400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9829_RS07415	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9829_RS07425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9829_RS07430	COG2088	sporulation resulting in formation of a cellular spore
D9829_RS07435	COG0251	oxidation-reduction process
D9829_RS07440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9829_RS07455	COG4466	Protein conserved in bacteria
D9829_RS07465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9829_RS07470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9829_RS07475	COG3583	domain protein
D9829_RS07475	COG3584	3D domain protein
D9829_RS07480	COG0084	hydrolase, TatD family'
D9829_RS07490	COG2002	toxin-antitoxin pair type II binding
D9829_RS07495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9829_RS07500	COG2827	Endonuclease containing a URI domain
D9829_RS07505	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9829_RS07510	COG4467	Involved in initiation control of chromosome replication
D9829_RS07515	COG1774	PSP1 C-terminal conserved region
D9829_RS07520	COG0470	DNA polymerase III
D9829_RS07525	COG1728	Protein conserved in bacteria
D9829_RS07530	COG3870	Protein conserved in bacteria
D9829_RS07535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9829_RS07540	COG1982	Orn Lys Arg decarboxylase major
D9829_RS07590	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9829_RS07595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9829_RS07600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9829_RS07610	COG0590	tRNA wobble adenosine to inosine editing
D9829_RS07615	COG1335	isochorismatase
D9829_RS07620	COG3858	chitin binding
D9829_RS07620	COG1388	LysM domain
D9829_RS07625	COG1428	Deoxynucleoside kinase
D9829_RS07630	COG1428	Deoxynucleoside kinase
D9829_RS07640	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9829_RS07645	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9829_RS07660	COG0517	IMP dehydrogenase activity
D9829_RS07660	COG0516	GMP reductase activity
D9829_RS07700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9829_RS07705	COG0187	DNA topoisomerase II activity
D9829_RS07715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9829_RS07720	COG2501	S4 domain
D9829_RS07725	COG0592	DNA-directed DNA polymerase activity
D9829_RS07730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9829_RS07740	COG0594	ribonuclease P activity
D9829_RS07750	COG1847	R3H domain protein
D9829_RS07755	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9829_RS07760	COG0445	tRNA wobble uridine modification
D9829_RS07770	COG1475	DNA binding
D9829_RS07775	COG1192	Involved in chromosome partitioning
D9829_RS07780	COG1475	DNA binding
D9829_RS07795	COG0668	transmembrane transport
D9829_RS07800	COG4481	Protein conserved in bacteria
D9829_RS07805	COG0243	molybdopterin cofactor binding
D9829_RS07810	COG0012	GTP binding
D9829_RS07825	COG0360	Binds together with S18 to 16S ribosomal RNA
D9829_RS07845	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9829_RS07850	COG0359	binds to the 23S rRNA
D9829_RS07855	COG0305	Participates in initiation and elongation during chromosome replication
D9829_RS07880	COG1196	nuclear chromosome segregation
D9829_RS07880	COG0741	lytic transglycosylase activity
D9829_RS07880	COG0739	heme binding
D9829_RS07885	COG0745	RESPONSE REGULATOR receiver
D9829_RS07890	COG5002	protein histidine kinase activity
D9829_RS07895	COG4863	YycH protein
D9829_RS07900	COG4853	Protein conserved in bacteria
D9829_RS07905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9829_RS07910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9829_RS07920	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9829_RS07925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9829_RS07935	COG0450	alkyl hydroperoxide reductase
D9829_RS07945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9829_RS07955	COG1070	Carbohydrate kinase
D9829_RS07970	COG0840	transmembrane signaling receptor activity
D9829_RS07985	COG5002	protein histidine kinase activity
D9829_RS07990	COG0745	RESPONSE REGULATOR receiver
D9829_RS08000	COG2208	phosphoserine phosphatase activity
D9829_RS08005	COG0596	Alpha beta hydrolase
D9829_RS08020	COG1294	oxidase, subunit
D9829_RS08025	COG1271	oxidase subunit
D9829_RS08030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9829_RS08035	COG2321	neutral zinc metallopeptidase
D9829_RS08050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9829_RS08060	COG3104	oligopeptide transport
D9829_RS08075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9829_RS08080	COG0402	S-adenosylhomocysteine deaminase activity
D9829_RS08090	COG5002	protein histidine kinase activity
D9829_RS08095	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9829_RS08100	COG0788	formyltetrahydrofolate deformylase activity
D9829_RS08105	COG0477	Major facilitator Superfamily
D9829_RS08125	COG0723	plastoquinol--plastocyanin reductase activity
D9829_RS08125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9829_RS08130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D9829_RS08140	COG3314	Sporulation integral membrane protein YlbJ
D9829_RS08150	COG0561	phosphatase activity
D9829_RS08165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9829_RS08170	COG0351	phosphomethylpyrimidine kinase
D9829_RS08175	COG0746	molybdenum cofactor guanylyltransferase activity
D9829_RS08180	COG0303	'Molybdopterin
D9829_RS08185	COG1910	domain protein
D9829_RS08190	COG0314	molybdopterin synthase activity
D9829_RS08200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9829_RS08210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9829_RS08220	COG2363	Small membrane protein
D9829_RS08230	COG3253	May function as heme-dependent peroxidase
D9829_RS08235	COG0280	phosphate acetyltransferase
D9829_RS08255	COG1078	dGTPase activity
D9829_RS08260	COG3465	dGTPase activity
D9829_RS08270	COG1994	Peptidase M50
D9829_RS08280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9829_RS08285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9829_RS08290	COG0010	Belongs to the arginase family
D9829_RS08295	COG4506	Protein conserved in bacteria
D9829_RS08300	COG0018	arginyl-trna synthetase
D9829_RS08305	COG4294	response to UV
D9829_RS08310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9829_RS08315	COG0247	lactate metabolic process
D9829_RS08315	COG2181	nitrate reductase activity
D9829_RS08320	COG0183	Belongs to the thiolase family
D9829_RS08325	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9829_RS08330	COG1960	acyl-CoA dehydrogenase activity
D9829_RS08335	COG1960	acyl-CoA dehydrogenase activity
D9829_RS08345	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9829_RS08345	COG1703	isobutyryl-CoA mutase activity
D9829_RS08345	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9829_RS08355	COG3343	RNA polymerase activity
D9829_RS08360	COG0504	CTP synthase activity
D9829_RS08365	COG4821	SIS domain
D9829_RS08370	COG2204	response regulator
D9829_RS08375	COG0191	fructose-bisphosphate aldolase activity
D9829_RS08380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9829_RS08385	COG1494	fructose-1,6-bisphosphatase
D9829_RS08390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9829_RS08400	COG1435	thymidine kinase activity
D9829_RS08410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9829_RS08435	COG0009	L-threonylcarbamoyladenylate synthase
D9829_RS08440	COG1971	Probably functions as a manganese efflux pump
D9829_RS08450	COG0698	ribose 5-phosphate isomerase
D9829_RS08465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9829_RS08470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9829_RS08475	COG1404	Belongs to the peptidase S8 family
D9829_RS08490	COG0356	it plays a direct role in the translocation of protons across the membrane
D9829_RS08495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9829_RS08500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9829_RS08505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9829_RS08520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9829_RS08525	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9829_RS08535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9829_RS08540	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9829_RS08545	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9829_RS08550	COG0649	NAD binding
D9829_RS08555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
D9829_RS08560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D9829_RS08565	COG0839	Belongs to the complex I subunit 6 family
D9829_RS08570	COG0713	ATP synthesis coupled electron transport
D9829_RS08575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9829_RS08585	COG1007	ATP synthesis coupled electron transport
D9829_RS08590	COG4836	Membrane
D9829_RS08605	COG2385	sporulation resulting in formation of a cellular spore
D9829_RS08625	COG0739	heme binding
D9829_RS08630	COG0768	penicillin binding
D9829_RS08635	COG2182	Extracellular solute-binding protein
D9829_RS08650	COG2972	Histidine kinase
D9829_RS08655	COG2207	Transcriptional regulator
D9829_RS08655	COG4753	response regulator
D9829_RS08660	COG0366	Alpha amylase catalytic
D9829_RS08680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9829_RS08690	COG2176	DNA-directed DNA polymerase activity
D9829_RS08695	COG1609	Transcriptional regulator
D9829_RS08785	COG1077	Cell shape determining protein MreB Mrl
D9829_RS08790	COG4786	Flagellar basal body rod
D9829_RS08795	COG4786	Flagellar basal body rod
D9829_RS08815	COG1131	(ABC) transporter
D9829_RS08820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9829_RS08835	COG1368	sulfuric ester hydrolase activity
D9829_RS08850	COG0629	single-stranded DNA binding
D9829_RS08865	COG3594	Acyltransferase
D9829_RS08880	COG4990	cell redox homeostasis
D9829_RS08885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9829_RS08890	COG4715	Zinc finger, swim domain protein
D9829_RS08910	COG0668	transmembrane transport
D9829_RS08930	COG0456	acetyltransferase
D9829_RS08960	COG1823	symporter activity
D9829_RS08985	COG0791	NLP P60 protein
D9829_RS08985	COG1388	LysM domain
D9829_RS09000	COG0489	protein tyrosine kinase activity
D9829_RS09005	COG4464	protein tyrosine phosphatase activity
D9829_RS09010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9829_RS09015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9829_RS09025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9829_RS09035	COG0438	transferase activity, transferring glycosyl groups
D9829_RS09050	COG2244	polysaccharide biosynthetic process
D9829_RS09065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9829_RS09110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9829_RS09115	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9829_RS09120	COG1733	regulation of RNA biosynthetic process
D9829_RS09140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS09150	COG1609	Transcriptional regulator
D9829_RS09155	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9829_RS09160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9829_RS09165	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9829_RS09170	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9829_RS09175	COG3958	Transketolase
D9829_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS09185	COG2188	Transcriptional regulator
D9829_RS09195	COG0205	6-phosphofructokinase activity
D9829_RS09210	COG0698	ribose 5-phosphate isomerase
D9829_RS09215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9829_RS09225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D9829_RS09230	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D9829_RS09230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D9829_RS09235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D9829_RS09235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D9829_RS09240	COG2186	Transcriptional regulator
D9829_RS09255	COG2814	Major facilitator Superfamily
D9829_RS09275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9829_RS09285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9829_RS09295	COG2814	Major facilitator Superfamily
D9829_RS09305	COG3949	Membrane
D9829_RS09315	COG3655	Transcriptional regulator
D9829_RS09320	COG3507	Belongs to the glycosyl hydrolase 43 family
D9829_RS09325	COG1115	amino acid carrier protein
D9829_RS09340	COG0402	S-adenosylhomocysteine deaminase activity
D9829_RS09350	COG2188	Transcriptional regulator
D9829_RS09355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9829_RS09360	COG1136	(ABC) transporter
D9829_RS09365	COG0577	efflux transmembrane transporter activity
D9829_RS09415	COG0671	phosphoesterase, PA-phosphatase related
D9829_RS09420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9829_RS09440	COG0667	Aldo Keto reductase
D9829_RS09450	COG0656	L-ascorbic acid biosynthetic process
D9829_RS09615	COG0640	Transcriptional regulator
D9829_RS09640	COG2723	6-phospho-beta-galactosidase activity
D9829_RS09650	COG2188	Transcriptional regulator
D9829_RS09660	COG1309	transcriptional regulator
D9829_RS09665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9829_RS09705	COG2226	methyltransferase
D9829_RS09735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9829_RS09740	COG1279	arginine transmembrane transporter activity
D9829_RS09745	COG0740	serine-type endopeptidase activity
D9829_RS09770	COG0456	acetyltransferase
D9829_RS09775	COG1335	isochorismatase
D9829_RS09780	COG1522	sequence-specific DNA binding
D9829_RS09785	COG2315	Protein conserved in bacteria
D9829_RS09795	COG0384	phenazine biosynthesis protein PhzF
D9829_RS09805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9829_RS09805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9829_RS09825	COG1959	2 iron, 2 sulfur cluster binding
D9829_RS09830	COG2910	NAD(P)H-binding
D9829_RS09930	COG3340	Belongs to the peptidase S51 family
D9829_RS09945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9829_RS09950	COG3584	3D domain protein
D9829_RS09950	COG1388	LysM domain
D9829_RS09975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS09995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9829_RS10025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D9829_RS10115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9829_RS10115	COG0456	acetyltransferase
D9829_RS10120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9829_RS10130	COG0579	oxidoreductase
D9829_RS10150	COG0252	asparaginase activity
D9829_RS10165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9829_RS10175	COG1116	anion transmembrane transporter activity
D9829_RS10190	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS10250	COG1176	ABC-type spermidine putrescine transport system, permease component I
D9829_RS10260	COG3842	ATPase activity
D9829_RS10265	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9829_RS10275	COG2204	response regulator
D9829_RS10290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D9829_RS10310	COG2213	PTS system mannitol-specific
D9829_RS10310	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS10315	COG3711	transcriptional antiterminator
D9829_RS10320	COG0246	Mannitol dehydrogenase
D9829_RS10330	COG2814	Major facilitator Superfamily
D9829_RS10370	COG1725	Transcriptional regulator
D9829_RS10380	COG0154	amidase activity
D9829_RS10405	COG3507	Belongs to the glycosyl hydrolase 43 family
D9829_RS10410	COG0546	phosphoglycolate phosphatase activity
D9829_RS10415	COG4977	sequence-specific DNA binding
D9829_RS10415	COG1917	Cupin 2, conserved barrel domain protein
D9829_RS10425	COG1132	(ABC) transporter
D9829_RS10430	COG1132	(ABC) transporter
D9829_RS10435	COG1609	Transcriptional regulator
D9829_RS10440	COG1653	transport
D9829_RS10445	COG1175	transmembrane transport
D9829_RS10450	COG0395	ABC-type sugar transport system, permease component
D9829_RS10455	COG3507	Belongs to the glycosyl hydrolase 43 family
D9829_RS10460	COG0667	Aldo Keto reductase
D9829_RS10470	COG1069	ribulokinase activity
D9829_RS10490	COG3534	alpha-L-arabinofuranosidase
D9829_RS10515	COG3940	Belongs to the glycosyl hydrolase 43 family
D9829_RS10520	COG3940	Belongs to the glycosyl hydrolase 43 family
D9829_RS10525	COG4990	cell redox homeostasis
D9829_RS10530	COG0483	inositol monophosphate 1-phosphatase activity
D9829_RS10540	COG2115	Belongs to the xylose isomerase family
D9829_RS10545	COG0477	Major facilitator Superfamily
D9829_RS10545	COG2814	Major facilitator Superfamily
D9829_RS10555	COG1733	regulation of RNA biosynthetic process
D9829_RS10560	COG2514	catechol 2,3-dioxygenase activity
D9829_RS10575	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9829_RS10575	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9829_RS10590	COG1994	Peptidase M50
D9829_RS10595	COG1115	amino acid carrier protein
D9829_RS10600	COG3300	MHYT domain
D9829_RS10600	COG5001	Diguanylate cyclase
D9829_RS10605	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9829_RS10610	COG1122	ATPase activity
D9829_RS10615	COG4721	ABC-type cobalt transport system, permease component
D9829_RS10625	COG0673	inositol 2-dehydrogenase activity
D9829_RS10630	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9829_RS10635	COG1653	transport
D9829_RS10640	COG1175	transmembrane transport
D9829_RS10645	COG0395	ABC-type sugar transport system, permease component
D9829_RS10650	COG5578	integral membrane protein
D9829_RS10665	COG2755	lipolytic protein G-D-S-L family
D9829_RS10680	COG1486	melibiose metabolic process
D9829_RS10690	COG1653	transport
D9829_RS10705	COG2323	membrane
D9829_RS10735	COG0604	alcohol dehydrogenase
D9829_RS10755	COG2972	Histidine kinase
D9829_RS10775	COG3250	beta-galactosidase activity
D9829_RS10785	COG4191	Histidine kinase
D9829_RS10800	COG2329	Antibiotic biosynthesis monooxygenase
D9829_RS10805	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9829_RS10810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9829_RS10815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9829_RS10820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9829_RS10835	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
D9829_RS10840	COG2234	aminopeptidase activity
D9829_RS10865	COG5002	protein histidine kinase activity
D9829_RS10870	COG0745	RESPONSE REGULATOR receiver
D9829_RS10880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9829_RS10885	COG0390	transport system, permease component
D9829_RS10890	COG1609	Transcriptional regulator
D9829_RS10895	COG2182	Extracellular solute-binding protein
D9829_RS10900	COG1175	transmembrane transport
D9829_RS10905	COG3833	ABC-type maltose transport systems, permease component
D9829_RS10910	COG1874	Beta-galactosidase
D9829_RS10915	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9829_RS10920	COG0805	protein transport
D9829_RS10925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9829_RS10935	COG0789	Transcriptional regulator
D9829_RS10940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS10955	COG2244	polysaccharide biosynthetic process
D9829_RS10960	COG0297	glycogen (starch) synthase activity
D9829_RS10960	COG0438	transferase activity, transferring glycosyl groups
D9829_RS10970	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9829_RS10975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9829_RS10980	COG3307	-O-antigen
D9829_RS10985	COG3206	protein involved in exopolysaccharide biosynthesis
D9829_RS10990	COG1215	transferase activity, transferring glycosyl groups
D9829_RS10995	COG0438	transferase activity, transferring glycosyl groups
D9829_RS11000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9829_RS11030	COG3584	3D domain protein
D9829_RS11030	COG1388	LysM domain
D9829_RS11035	COG1609	Transcriptional regulator
D9829_RS11045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9829_RS11050	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9829_RS11070	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9829_RS11075	COG3853	Toxic anion resistance protein (TelA)
D9829_RS11085	COG1215	transferase activity, transferring glycosyl groups
D9829_RS11110	COG2247	cell wall binding repeat
D9829_RS11110	COG2385	sporulation resulting in formation of a cellular spore
D9829_RS11115	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9829_RS11130	COG1316	TRANSCRIPTIONal
D9829_RS11140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9829_RS11145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9829_RS11150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9829_RS11155	COG1682	transport, permease protein
D9829_RS11160	COG1134	teichoic acid transport
D9829_RS11180	COG1388	LysM domain
D9829_RS11180	COG1705	Flagellar rod assembly protein muramidase FlgJ
D9829_RS11190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9829_RS11195	COG1316	TRANSCRIPTIONal
D9829_RS11200	COG1739	Uncharacterized protein family UPF0029
D9829_RS11205	COG4585	Histidine kinase
D9829_RS11210	COG2197	response regulator
D9829_RS11220	COG1307	EDD domain protein, DegV family
D9829_RS11225	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9829_RS11230	COG1040	competence protein
D9829_RS11240	COG2747	anti-sigma28 factor FlgM
D9829_RS11250	COG4786	Flagellar basal body rod
D9829_RS11250	COG1256	bacterial-type flagellum assembly
D9829_RS11255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9829_RS11265	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9829_RS11270	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9829_RS11280	COG3401	FG-GAP repeat protein
D9829_RS11290	COG1334	flagellar protein FlaG
D9829_RS11295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9829_RS11295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9829_RS11300	COG1516	flagellar protein fliS
D9829_RS11320	COG0653	protein targeting
D9829_RS11335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS11345	COG2884	Cell division ATP-binding protein ftsE
D9829_RS11350	COG2177	Part of the ABC transporter FtsEX involved in
D9829_RS11355	COG3883	PFAM NLP P60 protein
D9829_RS11355	COG0791	NLP P60 protein
D9829_RS11360	COG3409	Peptidoglycan-binding domain 1 protein
D9829_RS11360	COG0793	Belongs to the peptidase S41A family
D9829_RS11365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9829_RS11370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS11375	COG0346	lactoylglutathione lyase activity
D9829_RS11380	COG0833	amino acid
D9829_RS11385	COG0400	carboxylic ester hydrolase activity
D9829_RS11395	COG0398	Pfam SNARE associated Golgi protein
D9829_RS11400	COG2357	RelA SpoT domain protein
D9829_RS11405	COG2223	nitrite transmembrane transporter activity
D9829_RS11410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9829_RS11415	COG0243	molybdopterin cofactor binding
D9829_RS11420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9829_RS11425	COG2146	nitrite reductase [NAD(P)H] activity
D9829_RS11430	COG1587	Uroporphyrinogen-III synthase
D9829_RS11435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS11445	COG0556	nucleotide-excision repair
D9829_RS11450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9829_RS11455	COG0726	polysaccharide deacetylase
D9829_RS11460	COG3595	metallopeptidase activity
D9829_RS11465	COG1950	PFAM Membrane protein of
D9829_RS11480	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9829_RS11490	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9829_RS11495	COG0546	phosphoglycolate phosphatase activity
D9829_RS11500	COG0110	maltose O-acetyltransferase activity
D9829_RS11505	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D9829_RS11505	COG3264	Mechanosensitive ion channel
D9829_RS11510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9829_RS11515	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9829_RS11520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9829_RS11525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9829_RS11530	COG0131	Imidazoleglycerol-phosphate dehydratase
D9829_RS11535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9829_RS11540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9829_RS11545	COG0107	imidazoleglycerol-phosphate synthase activity
D9829_RS11550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9829_RS11550	COG0140	phosphoribosyl-ATP diphosphatase activity
D9829_RS11555	COG0457	Tetratricopeptide repeat
D9829_RS11560	COG0492	ferredoxin-NADP+ reductase activity
D9829_RS11565	COG1051	belongs to the nudix hydrolase family
D9829_RS11570	COG1660	Displays ATPase and GTPase activities
D9829_RS11575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9829_RS11580	COG1481	regulation of sporulation
D9829_RS11585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS11590	COG0740	serine-type endopeptidase activity
D9829_RS11600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9829_RS11620	COG0126	phosphoglycerate kinase activity
D9829_RS11635	COG0148	phosphopyruvate hydratase activity
D9829_RS11640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9829_RS11645	COG1647	Serine aminopeptidase, S33
D9829_RS11650	COG0557	exoribonuclease II activity
D9829_RS11655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9829_RS11665	COG1349	DNA-binding transcription factor activity
D9829_RS11670	COG1879	ABC-type sugar transport system periplasmic component
D9829_RS11675	COG1129	ABC transporter
D9829_RS11680	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9829_RS11685	COG1621	beta-fructofuranosidase activity
D9829_RS11690	COG1070	Carbohydrate kinase
D9829_RS11700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9829_RS11720	COG1846	Transcriptional regulator
D9829_RS11725	COG2409	Drug exporters of the RND superfamily
D9829_RS11725	COG1033	growth of symbiont in host cell
D9829_RS11730	COG1929	Belongs to the glycerate kinase type-1 family
D9829_RS11735	COG0471	metal ion transport
D9829_RS11740	COG1785	Belongs to the alkaline phosphatase family
D9829_RS11745	COG2391	methyltransferase activity
D9829_RS11750	COG1785	Belongs to the alkaline phosphatase family
D9829_RS11760	COG0745	RESPONSE REGULATOR receiver
D9829_RS11765	COG3850	Histidine kinase
D9829_RS11765	COG5002	protein histidine kinase activity
D9829_RS11775	COG3212	peptidase
D9829_RS11780	COG3212	peptidase
D9829_RS11785	COG1764	response to oxidative stress
D9829_RS11795	COG0673	inositol 2-dehydrogenase activity
D9829_RS11800	COG1063	alcohol dehydrogenase
D9829_RS11810	COG1114	Component of the transport system for branched-chain amino acids
D9829_RS11830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9829_RS11850	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS11870	COG1910	domain protein
D9829_RS11875	COG0772	Belongs to the SEDS family
D9829_RS11895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9829_RS11900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS11905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS11910	COG1120	ATPase activity
D9829_RS11925	COG0506	proline dehydrogenase activity
D9829_RS11935	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9829_RS11935	COG1024	Enoyl-CoA hydratase
D9829_RS11940	COG0183	Belongs to the thiolase family
D9829_RS11945	COG1960	acyl-CoA dehydrogenase activity
D9829_RS11950	COG1393	Belongs to the ArsC family
D9829_RS11955	COG0509	glycine decarboxylation via glycine cleavage system
D9829_RS11965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9829_RS11970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS11975	COG2873	o-acetylhomoserine
D9829_RS11980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9829_RS11985	COG2011	ABC-type metal ion transport system permease component
D9829_RS11990	COG1464	Belongs to the NlpA lipoprotein family
D9829_RS11995	COG0396	ATPase activity
D9829_RS12000	COG0719	Fe-S assembly protein
D9829_RS12005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9829_RS12010	COG0822	iron-sulfur transferase activity
D9829_RS12015	COG0719	Fe-S assembly protein
D9829_RS12020	COG2801	Transposase and inactivated derivatives
D9829_RS12030	COG1801	Protein of unknown function DUF72
D9829_RS12035	COG0737	Belongs to the 5'-nucleotidase family
D9829_RS12040	COG3377	Domain of unknown function (DUF1805)
D9829_RS12050	COG0733	neurotransmitter:sodium symporter activity
D9829_RS12060	COG0739	heme binding
D9829_RS12065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9829_RS12075	COG4470	Protein conserved in bacteria
D9829_RS12090	COG2445	Protein of unknown function DUF86
D9829_RS12095	COG0647	UMP catabolic process
D9829_RS12100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9829_RS12105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9829_RS12110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9829_RS12115	COG0460	homoserine dehydrogenase
D9829_RS12120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9829_RS12125	COG0083	homoserine kinase activity
D9829_RS12130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9829_RS12135	COG4837	Protein of unknown function (DUF1462)
D9829_RS12140	COG1252	NADH dehydrogenase
D9829_RS12145	COG4844	belongs to the
D9829_RS12150	COG0316	Belongs to the HesB IscA family
D9829_RS12155	COG1252	NADH dehydrogenase
D9829_RS12170	COG3584	3D domain protein
D9829_RS12175	COG0653	protein targeting
D9829_RS12180	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9829_RS12190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9829_RS12195	COG2056	Na+-H+ antiporter family
D9829_RS12200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9829_RS12215	COG2050	protein possibly involved in aromatic compounds catabolism
D9829_RS12225	COG1320	monovalent cation:proton antiporter activity
D9829_RS12230	COG2212	antiporter activity
D9829_RS12235	COG1863	multisubunit Na H antiporter MnhE subunit
D9829_RS12240	COG0651	ATP synthesis coupled electron transport
D9829_RS12245	COG1006	Multisubunit Na H antiporter MnhC subunit
D9829_RS12250	COG2111	Na H antiporter
D9829_RS12255	COG2111	Na H antiporter
D9829_RS12255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9829_RS12265	COG5018	Exonuclease
D9829_RS12275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9829_RS12285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9829_RS12295	COG2267	carboxylic ester hydrolase activity
D9829_RS12300	COG1522	sequence-specific DNA binding
D9829_RS12305	COG0436	Aminotransferase
D9829_RS12315	COG1098	S1 RNA binding domain
D9829_RS12320	COG2155	Conserved Protein
D9829_RS12325	COG1979	alcohol dehydrogenase
D9829_RS12340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9829_RS12350	COG0697	spore germination
D9829_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS12370	COG0569	domain protein
D9829_RS12380	COG2268	Band 7 protein
D9829_RS12385	COG1585	Membrane protein implicated in regulation of membrane protease activity
D9829_RS12390	COG2059	Chromate
D9829_RS12395	COG2059	Chromate
D9829_RS12405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9829_RS12425	COG2733	membrane
D9829_RS12430	COG0405	Gamma-glutamyltransferase
D9829_RS12435	COG2172	sigma factor antagonist activity
D9829_RS12450	COG2814	Major facilitator Superfamily
D9829_RS12455	COG2217	Heavy metal translocating P-type atpase
D9829_RS12460	COG0745	RESPONSE REGULATOR receiver
D9829_RS12465	COG3850	Histidine kinase
D9829_RS12465	COG5002	protein histidine kinase activity
D9829_RS12470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9829_RS12495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS12495	COG3711	transcriptional antiterminator
D9829_RS12500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS12505	COG2706	6-phosphogluconolactonase activity
D9829_RS12510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS12515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS12520	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9829_RS12525	COG1486	melibiose metabolic process
D9829_RS12530	COG2723	6-phospho-beta-galactosidase activity
D9829_RS12540	COG1368	sulfuric ester hydrolase activity
D9829_RS12545	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS12550	COG4605	iron ion homeostasis
D9829_RS12555	COG4604	ABC transporter, ATP-binding protein
D9829_RS12560	COG0753	catalase activity
D9829_RS12575	COG3773	Cell wall hydrolase
D9829_RS12580	COG2186	Transcriptional regulator
D9829_RS12585	COG0277	FAD linked oxidase domain protein
D9829_RS12590	COG0247	lactate metabolic process
D9829_RS12595	COG0277	FAD linked oxidase domain protein
D9829_RS12600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D9829_RS12605	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9829_RS12610	COG1620	l-lactate permease
D9829_RS12615	COG1609	Transcriptional regulator
D9829_RS12620	COG1263	PTS System
D9829_RS12620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS12625	COG1621	beta-fructofuranosidase activity
D9829_RS12630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS12635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9829_RS12640	COG3401	FG-GAP repeat protein
D9829_RS12645	COG3711	transcriptional antiterminator
D9829_RS12655	COG2723	6-phospho-beta-galactosidase activity
D9829_RS12660	COG0586	Pfam SNARE associated Golgi protein
D9829_RS12670	COG1253	flavin adenine dinucleotide binding
D9829_RS12675	COG3401	FG-GAP repeat protein
D9829_RS12680	COG3347	Dehydrogenase
D9829_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS12685	COG1609	Transcriptional regulator
D9829_RS12685	COG2207	Transcriptional regulator
D9829_RS12690	COG1070	Carbohydrate kinase
D9829_RS12695	COG4806	L-rhamnose isomerase
D9829_RS12700	COG1349	DNA-binding transcription factor activity
D9829_RS12710	COG1454	alcohol dehydrogenase
D9829_RS12715	COG2188	Transcriptional regulator
D9829_RS12720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS12725	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9829_RS12730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS12735	COG2723	6-phospho-beta-galactosidase activity
D9829_RS12740	COG1940	carbohydrate kinase activity
D9829_RS12745	COG1482	cell wall glycoprotein biosynthetic process
D9829_RS12755	COG0667	Aldo Keto reductase
D9829_RS12760	COG2814	Major facilitator Superfamily
D9829_RS12765	COG3458	cephalosporin-C deacetylase activity
D9829_RS12775	COG1940	carbohydrate kinase activity
D9829_RS12785	COG1175	transmembrane transport
D9829_RS12790	COG0395	ABC-type sugar transport system, permease component
D9829_RS12795	COG2182	Extracellular solute-binding protein
D9829_RS12805	COG2723	6-phospho-beta-galactosidase activity
D9829_RS12810	COG0673	inositol 2-dehydrogenase activity
D9829_RS12815	COG0673	inositol 2-dehydrogenase activity
D9829_RS12820	COG1175	transmembrane transport
D9829_RS12825	COG0395	ABC-type sugar transport system, permease component
D9829_RS12830	COG1653	transport
D9829_RS12835	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9829_RS12840	COG3866	Pectate lyase
D9829_RS12845	COG3275	phosphorelay sensor kinase activity
D9829_RS12850	COG4753	response regulator
D9829_RS12850	COG2207	Transcriptional regulator
D9829_RS12860	COG1609	Transcriptional regulator
D9829_RS12865	COG0246	Mannitol dehydrogenase
D9829_RS12870	COG2721	sulfolactate sulfo-lyase activity
D9829_RS12885	COG2972	Histidine kinase
D9829_RS12890	COG2207	Transcriptional regulator
D9829_RS12890	COG4753	response regulator
D9829_RS12895	COG1653	transport
D9829_RS12900	COG2207	Transcriptional regulator
D9829_RS12905	COG5578	integral membrane protein
D9829_RS12910	COG1874	Beta-galactosidase
D9829_RS12915	COG0823	Involved in the tonB-independent uptake of proteins
D9829_RS12925	COG1653	transport
D9829_RS12930	COG4209	transmembrane transport
D9829_RS12935	COG0395	ABC-type sugar transport system, permease component
D9829_RS12940	COG2755	lipolytic protein G-D-S-L family
D9829_RS12945	COG1874	Beta-galactosidase
D9829_RS12950	COG1414	Transcriptional regulator
D9829_RS12955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9829_RS12975	COG1349	DNA-binding transcription factor activity
D9829_RS12980	COG3254	rhamnose metabolic process
D9829_RS12985	COG0800	Aldolase
D9829_RS12995	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9829_RS13000	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS13020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9829_RS13035	COG1278	Cold shock
D9829_RS13045	COG1285	pathogenesis
D9829_RS13180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9829_RS13185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9829_RS13190	COG0297	glycogen (starch) synthase activity
D9829_RS13195	COG0058	SHG alpha-glucan phosphorylase activity
D9829_RS13205	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9829_RS13215	COG1575	Belongs to the MenA family. Type 1 subfamily
D9829_RS13220	COG1169	isochorismate synthase
D9829_RS13225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9829_RS13230	COG0596	Alpha beta hydrolase
D9829_RS13235	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9829_RS13240	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS13245	COG4948	Mandelate Racemase Muconate Lactonizing
D9829_RS13265	COG0288	reversible hydration of carbon dioxide
D9829_RS13270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9829_RS13275	COG1854	S-ribosylhomocysteine lyase activity
D9829_RS13285	COG0783	Belongs to the Dps family
D9829_RS13305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9829_RS13310	COG1116	anion transmembrane transporter activity
D9829_RS13315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9829_RS13320	COG1506	peptidase
D9829_RS13335	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9829_RS13340	COG0367	asparagine synthase
D9829_RS13345	COG4990	cell redox homeostasis
D9829_RS13350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9829_RS13355	COG2267	carboxylic ester hydrolase activity
D9829_RS13365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9829_RS13370	COG1242	4 iron, 4 sulfur cluster binding
D9829_RS13385	COG2814	Major facilitator Superfamily
D9829_RS13390	COG1556	Lactate utilization protein
D9829_RS13395	COG1139	Iron-sulfur cluster binding protein
D9829_RS13400	COG0247	lactate metabolic process
D9829_RS13405	COG2186	Transcriptional regulator
D9829_RS13410	COG0495	leucyl-tRNA aminoacylation
D9829_RS13420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9829_RS13435	COG2081	HI0933 family
D9829_RS13440	COG2244	polysaccharide biosynthetic process
D9829_RS13450	COG1187	pseudouridine synthase activity
D9829_RS13455	COG1349	DNA-binding transcription factor activity
D9829_RS13460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9829_RS13470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9829_RS13475	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9829_RS13490	COG1523	belongs to the glycosyl hydrolase 13 family
D9829_RS13495	COG0510	thiamine kinase activity
D9829_RS13505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9829_RS13510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS13520	COG1363	Peptidase, m42
D9829_RS13525	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D9829_RS13540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS13545	COG4848	Belongs to the UPF0354 family
D9829_RS13550	COG1674	ftsk spoiiie
D9829_RS13555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9829_RS13565	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9829_RS13570	COG4980	gas vesicle protein
D9829_RS13575	COG3118	belongs to the thioredoxin family
D9829_RS13580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9829_RS13580	COG1605	Chorismate mutase
D9829_RS13590	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9829_RS13595	COG0517	IMP dehydrogenase activity
D9829_RS13600	COG0454	-acetyltransferase
D9829_RS13605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9829_RS13620	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9829_RS13630	COG1956	GAF domain-containing protein
D9829_RS13635	COG1309	transcriptional regulator
D9829_RS13640	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9829_RS13645	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9829_RS13650	COG1104	cysteine desulfurase activity
D9829_RS13655	COG0301	tRNA thio-modification
D9829_RS13665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9829_RS13670	COG2962	Rard protein
D9829_RS13675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9829_RS13680	COG0616	signal peptide processing
D9829_RS13685	COG1714	RDD family
D9829_RS13695	COG3874	Sporulation protein YtfJ
D9829_RS13700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9829_RS13705	COG0827	DNA restriction-modification system
D9829_RS13710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9829_RS13720	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9829_RS13730	COG0137	argininosuccinate synthase activity
D9829_RS13735	COG0165	Argininosuccinate lyase
D9829_RS13740	COG0589	response to stress
D9829_RS13755	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9829_RS13760	COG0006	proline dipeptidase activity
D9829_RS13765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9829_RS13775	COG4109	DRTGG domain
D9829_RS13785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9829_RS13800	COG0587	DNA-directed DNA polymerase activity
D9829_RS13805	COG0281	malic enzyme
D9829_RS13810	COG1725	Transcriptional regulator
D9829_RS13815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9829_RS13820	COG0825	malonyl-CoA metabolic process
D9829_RS13825	COG0205	6-phosphofructokinase activity
D9829_RS13835	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9829_RS13840	COG0628	permease
D9829_RS13845	COG2707	UPF0756 membrane protein
D9829_RS13850	COG0372	Belongs to the citrate synthase family
D9829_RS13855	COG0538	isocitrate dehydrogenase activity
D9829_RS13860	COG0039	L-malate dehydrogenase activity
D9829_RS13870	COG0745	RESPONSE REGULATOR receiver
D9829_RS13875	COG5002	protein histidine kinase activity
D9829_RS13880	COG0330	HflC and HflK could
D9829_RS13885	COG0330	HflC and HflK could
D9829_RS13890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9829_RS13890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9829_RS13895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9829_RS13900	COG0737	Belongs to the 5'-nucleotidase family
D9829_RS13905	COG1971	Probably functions as a manganese efflux pump
D9829_RS13915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9829_RS13930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9829_RS13935	COG3611	Membrane attachment protein
D9829_RS13940	COG1484	DNA-dependent DNA replication
D9829_RS13950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9829_RS13955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9829_RS13965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9829_RS13970	COG3326	Membrane
D9829_RS13985	COG1363	Peptidase, m42
D9829_RS13995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9829_RS14000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9829_RS14005	COG0072	phenylalanine-tRNA ligase activity
D9829_RS14005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9829_RS14010	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9829_RS14015	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9829_RS14020	COG1286	toxin biosynthetic process
D9829_RS14025	COG1796	DNA polymerase
D9829_RS14025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9829_RS14035	COG3766	membrane
D9829_RS14040	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS14045	COG1309	transcriptional regulator
D9829_RS14050	COG1024	Enoyl-CoA hydratase
D9829_RS14055	COG2086	electron transfer activity
D9829_RS14060	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9829_RS14065	COG3118	belongs to the thioredoxin family
D9829_RS14070	COG0322	excinuclease ABC activity
D9829_RS14080	COG1719	4-vinyl reductase, 4VR
D9829_RS14085	COG2009	succinate dehydrogenase
D9829_RS14090	COG1053	succinate dehydrogenase
D9829_RS14095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9829_RS14105	COG0444	Belongs to the ABC transporter superfamily
D9829_RS14110	COG4608	Belongs to the ABC transporter superfamily
D9829_RS14115	COG0747	negative chemotaxis
D9829_RS14120	COG0601	transmembrane transport
D9829_RS14125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9829_RS14130	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
D9829_RS14140	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
D9829_RS14145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D9829_RS14150	COG2080	2 iron, 2 sulfur cluster binding
D9829_RS14155	COG1523	belongs to the glycosyl hydrolase 13 family
D9829_RS14160	COG2197	response regulator
D9829_RS14165	COG1846	Transcriptional regulator
D9829_RS14175	COG5401	PFAM Sporulation and spore germination
D9829_RS14185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9829_RS14190	COG0622	Phosphoesterase
D9829_RS14200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9829_RS14205	COG0028	Belongs to the TPP enzyme family
D9829_RS14210	COG0440	acetolactate synthase activity
D9829_RS14215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9829_RS14220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9829_RS14230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9829_RS14235	COG0066	3-isopropylmalate dehydratase activity
D9829_RS14245	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9829_RS14255	COG1067	ATP-dependent peptidase activity
D9829_RS14255	COG0470	DNA polymerase III
D9829_RS14260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9829_RS14265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9829_RS14280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9829_RS14285	COG0181	hydroxymethylbilane synthase activity
D9829_RS14295	COG0113	porphobilinogen synthase activity
D9829_RS14300	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9829_RS14305	COG1388	LysM domain
D9829_RS14320	COG0525	valine-tRNA ligase activity
D9829_RS14325	COG0285	dihydrofolate synthase activity
D9829_RS14330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9829_RS14345	COG2003	Belongs to the UPF0758 family
D9829_RS14350	COG1077	Cell shape determining protein MreB Mrl
D9829_RS14355	COG1792	Involved in formation and maintenance of cell shape
D9829_RS14365	COG0850	regulation of cytokinetic process
D9829_RS14370	COG2894	cell division
D9829_RS14375	COG0739	heme binding
D9829_RS14380	COG1994	Peptidase M50
D9829_RS14385	COG1530	ribonuclease E activity
D9829_RS14390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9829_RS14395	COG2868	ribosomal protein
D9829_RS14405	COG3290	protein histidine kinase activity
D9829_RS14410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9829_RS14415	COG4492	Belongs to the UPF0735 family
D9829_RS14420	COG0077	Prephenate dehydratase
D9829_RS14425	COG1827	regulation of RNA biosynthetic process
D9829_RS14430	COG1104	cysteine desulfurase activity
D9829_RS14435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9829_RS14440	COG0157	Belongs to the NadC ModD family
D9829_RS14485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9829_RS14495	COG1862	Preprotein translocase
D9829_RS14505	COG2323	membrane
D9829_RS14510	COG2244	polysaccharide biosynthetic process
D9829_RS14520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9829_RS14520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9829_RS14525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9829_RS14525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9829_RS14530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9829_RS14535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9829_RS14540	COG1490	D-aminoacyl-tRNA deacylase activity
D9829_RS14545	COG3103	Sh3 type 3 domain protein
D9829_RS14545	COG4991	sh3 domain protein
D9829_RS14545	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9829_RS14550	COG0124	histidyl-tRNA synthetase
D9829_RS14555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9829_RS14565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9829_RS14575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9829_RS14600	COG1793	dna ligase
D9829_RS14675	COG1715	Restriction endonuclease
D9829_RS14680	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9829_RS14745	COG1959	2 iron, 2 sulfur cluster binding
D9829_RS14750	COG1104	cysteine desulfurase activity
D9829_RS14765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9829_RS14770	COG3881	PFAM PRC-barrel domain
D9829_RS14780	COG0628	permease
D9829_RS14785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9829_RS14790	COG4472	Bacterial protein of unknown function (DUF965)
D9829_RS14795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9829_RS14800	COG3906	Belongs to the UPF0473 family
D9829_RS14805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9829_RS14810	COG4122	O-methyltransferase activity
D9829_RS14815	COG0826	peptidase U32
D9829_RS14820	COG0826	peptidase U32
D9829_RS14825	COG0572	uridine kinase
D9829_RS14830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9829_RS14835	COG0768	penicillin binding
D9829_RS14850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9829_RS14875	COG0688	phosphatidylethanolamine metabolic process
D9829_RS14885	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9829_RS14890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9829_RS14900	COG1534	Rna-binding protein
D9829_RS14905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9829_RS14910	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9829_RS14915	COG0799	negative regulation of ribosome biogenesis
D9829_RS14920	COG2226	methyltransferase
D9829_RS14925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9829_RS14930	COG1596	polysaccharide export
D9829_RS14930	COG1555	photosystem II stabilization
D9829_RS14935	COG2131	deaminase
D9829_RS14940	COG2333	competence protein COMEC
D9829_RS14940	COG0658	competence protein
D9829_RS14950	COG1466	dna polymerase III delta subunit
D9829_RS14955	COG0268	Binds directly to 16S ribosomal RNA
D9829_RS14960	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9829_RS14965	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9829_RS14975	COG0481	GTPase activity
D9829_RS14980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9829_RS14985	COG1420	regulation of RNA biosynthetic process
D9829_RS14990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9829_RS14995	COG0443	Heat shock 70 kDa protein
D9829_RS15000	COG0484	heat shock protein binding
D9829_RS15005	COG2264	protein methyltransferase activity
D9829_RS15010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9829_RS15015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9829_RS15020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9829_RS15025	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9829_RS15030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9829_RS15035	COG1610	YqeY-like protein
D9829_RS15040	COG1030	water channel activity
D9829_RS15045	COG4864	UPF0365 protein
D9829_RS15065	COG1702	phosphate starvation-inducible protein PhoH
D9829_RS15070	COG1480	7TM receptor with intracellular HD hydrolase
D9829_RS15075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9829_RS15080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9829_RS15085	COG0295	cytidine deaminase activity
D9829_RS15100	COG1381	Involved in DNA repair and RecF pathway recombination
D9829_RS15110	COG0751	glycine-tRNA ligase activity
D9829_RS15115	COG0517	IMP dehydrogenase activity
D9829_RS15120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9829_RS15125	COG1671	Belongs to the UPF0178 family
D9829_RS15130	COG0358	DNA primase activity
D9829_RS15135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9829_RS15140	COG2010	Cytochrome c
D9829_RS15145	COG2384	SAM-dependent methyltransferase
D9829_RS15150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9829_RS15155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9829_RS15170	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9829_RS15180	COG1121	(ABC) transporter
D9829_RS15185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9829_RS15190	COG0735	belongs to the Fur family
D9829_RS15200	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9829_RS15215	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9829_RS15225	COG5521	maltodextrose utilization protein MalA
D9829_RS15230	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9829_RS15235	COG2839	Protein conserved in bacteria
D9829_RS15240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9829_RS15250	COG0477	Major facilitator Superfamily
D9829_RS15255	COG0768	penicillin binding
D9829_RS15260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9829_RS15265	COG0573	inorganic phosphate transmembrane transporter activity
D9829_RS15270	COG0581	inorganic phosphate transmembrane transporter activity
D9829_RS15275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9829_RS15280	COG0704	Plays a role in the regulation of phosphate uptake
D9829_RS15300	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9829_RS15320	COG0705	Rhomboid family
D9829_RS15320	COG0457	Tetratricopeptide repeat
D9829_RS15330	COG0697	spore germination
D9829_RS15340	COG1940	carbohydrate kinase activity
D9829_RS15345	COG1368	sulfuric ester hydrolase activity
D9829_RS15355	COG0011	TIGRFAM Protein of
D9829_RS15370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS15390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9829_RS15395	COG1459	type II secretion system
D9829_RS15400	COG4537	Required for transformation and DNA binding
D9829_RS15435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9829_RS15440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9829_RS15445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9829_RS15450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9829_RS15455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9829_RS15460	COG0095	Lipoate-protein ligase
D9829_RS15465	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9829_RS15475	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9829_RS15485	COG3872	metal-dependent enzyme
D9829_RS15495	COG0006	proline dipeptidase activity
D9829_RS15500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9829_RS15510	COG3854	ATPases associated with a variety of cellular activities
D9829_RS15550	COG0511	ligase activity, forming carbon-carbon bonds
D9829_RS15555	COG0439	Biotin carboxylase
D9829_RS15560	COG1302	Protein conserved in bacteria
D9829_RS15575	COG1570	exodeoxyribonuclease VII activity
D9829_RS15580	COG1722	exodeoxyribonuclease VII activity
D9829_RS15590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9829_RS15595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9829_RS15605	COG0497	DNA recombination
D9829_RS15610	COG0750	zinc metalloprotease
D9829_RS15620	COG0745	RESPONSE REGULATOR receiver
D9829_RS15625	COG3093	addiction module antidote protein HigA
D9829_RS15630	COG0584	glycerophosphoryl diester phosphodiesterase
D9829_RS15640	COG3829	transcription factor binding
D9829_RS15640	COG3290	protein histidine kinase activity
D9829_RS15650	COG3426	butyrate kinase activity
D9829_RS15655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9829_RS15660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9829_RS15665	COG0022	dehydrogenase e1 component
D9829_RS15670	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9829_RS15685	COG1703	isobutyryl-CoA mutase activity
D9829_RS15695	COG4129	membrane
D9829_RS15700	COG1376	ErfK ybiS ycfS ynhG family protein
D9829_RS15705	COG0346	lactoylglutathione lyase activity
D9829_RS15710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9829_RS15715	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9829_RS15725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9829_RS15730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9829_RS15735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9829_RS15740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9829_RS15745	COG1234	tRNA 3'-trailer cleavage
D9829_RS15750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9829_RS15760	COG0300	oxidoreductase activity
D9829_RS15770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9829_RS15795	COG1073	alpha beta
D9829_RS15805	COG0456	acetyltransferase
D9829_RS15805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9829_RS15810	COG0667	Aldo Keto reductase
D9829_RS15825	COG1379	DNA repair
D9829_RS15830	COG1300	Membrane
D9829_RS15835	COG0735	belongs to the Fur family
D9829_RS15845	COG4974	Belongs to the 'phage' integrase family
D9829_RS15865	COG1686	Belongs to the peptidase S11 family
D9829_RS15875	COG2172	sigma factor antagonist activity
D9829_RS15900	COG0697	spore germination
D9829_RS15915	COG1547	Domain of unknown function (DUF309)
D9829_RS15925	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9829_RS15945	COG1686	Belongs to the peptidase S11 family
D9829_RS15950	COG2715	membrane protein required for spore maturation
D9829_RS15955	COG0700	Nucleoside recognition
D9829_RS15960	COG1187	pseudouridine synthase activity
D9829_RS15965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS15970	COG1333	cytochrome c biogenesis protein
D9829_RS15975	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9829_RS15980	COG0745	RESPONSE REGULATOR receiver
D9829_RS15985	COG5002	protein histidine kinase activity
D9829_RS15990	COG1595	DNA-templated transcription, initiation
D9829_RS16005	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9829_RS16010	COG1141	Ferredoxin
D9829_RS16015	COG4955	Helix-turn-helix domain
D9829_RS16020	COG0514	ATP-dependent DNA helicase (RecQ)
D9829_RS16025	COG1266	CAAX protease self-immunity
D9829_RS16030	COG1388	LysM domain
D9829_RS16050	COG1408	metallophosphoesterase
D9829_RS16055	COG4862	establishment of competence for transformation
D9829_RS16060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9829_RS16065	COG0492	ferredoxin-NADP+ reductase activity
D9829_RS16070	COG0252	asparaginase activity
D9829_RS16075	COG2339	peptidase activity
D9829_RS16080	COG3409	Peptidoglycan-binding domain 1 protein
D9829_RS16080	COG3773	Cell wall hydrolase
D9829_RS16085	COG2959	enzyme of heme biosynthesis
D9829_RS16100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9829_RS16110	COG0539	negative regulation of cytoplasmic translation
D9829_RS16140	COG1160	GTP binding
D9829_RS16145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9829_RS16160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9829_RS16165	COG0776	regulation of translation
D9829_RS16170	COG0302	gtp cyclohydrolase
D9829_RS16185	COG2226	methyltransferase
D9829_RS16190	COG0142	geranyltranstransferase activity
D9829_RS16195	COG0105	UTP biosynthetic process
D9829_RS16200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9829_RS16205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9829_RS16210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9829_RS16215	COG4401	Chorismate mutase type I
D9829_RS16220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9829_RS16225	COG0287	Prephenate dehydrogenase
D9829_RS16230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9829_RS16240	COG0457	Tetratricopeptide repeat
D9829_RS16245	COG5582	Belongs to the UPF0302 family
D9829_RS16255	COG0723	plastoquinol--plastocyanin reductase activity
D9829_RS16270	COG4347	Protein of unknown function (DUF1405)
D9829_RS16280	COG2738	Putative neutral zinc metallopeptidase
D9829_RS16285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS16290	COG1694	Mazg nucleotide pyrophosphohydrolase
D9829_RS16300	COG1803	Methylglyoxal synthase
D9829_RS16305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9829_RS16310	COG0438	transferase activity, transferring glycosyl groups
D9829_RS16325	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9829_RS16330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9829_RS16335	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9829_RS16340	COG1199	ATP-dependent helicase activity
D9829_RS16340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9829_RS16360	COG0017	Asparaginyl-tRNA synthetase
D9829_RS16365	COG3935	DnaD domain protein
D9829_RS16370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9829_RS16380	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9829_RS16380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9829_RS16385	COG3331	DNA recombination
D9829_RS16415	COG1151	hydroxylamine reductase activity
D9829_RS16420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9829_RS16425	COG1205	dead DEAH box helicase
D9829_RS16425	COG1111	helicase
D9829_RS16430	COG3359	exonuclease
D9829_RS16455	COG0116	Belongs to the methyltransferase superfamily
D9829_RS16460	COG1199	ATP-dependent helicase activity
D9829_RS16465	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9829_RS16470	COG0697	spore germination
D9829_RS16475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9829_RS16480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9829_RS16495	COG2233	PERMEase
D9829_RS16500	COG1278	Cold shock
D9829_RS16510	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS16515	COG3424	synthase
D9829_RS16520	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9829_RS16525	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9829_RS16530	COG3541	Predicted nucleotidyltransferase
D9829_RS16540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9829_RS16550	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9829_RS16565	COG0328	RNA-DNA hybrid ribonuclease activity
D9829_RS16570	COG0328	RNA-DNA hybrid ribonuclease activity
D9829_RS16580	COG1278	Cold shock
D9829_RS16595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9829_RS16600	COG1321	iron dependent repressor
D9829_RS16620	COG1307	EDD domain protein, DegV family
D9829_RS16625	COG1418	mRNA catabolic process
D9829_RS16630	COG0488	(ABC) transporter
D9829_RS16635	COG1413	lyase activity
D9829_RS16650	COG2136	Putative SAM-dependent methyltransferase
D9829_RS16650	COG2521	methyltransferase
D9829_RS16670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9829_RS16675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9829_RS16680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9829_RS16685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9829_RS16690	COG0805	protein transport
D9829_RS16695	COG1307	EDD domain protein, DegV family
D9829_RS16700	COG1999	signal sequence binding
D9829_RS16705	COG2755	lipolytic protein G-D-S-L family
D9829_RS16720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9829_RS16725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9829_RS16745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9829_RS16750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9829_RS16755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9829_RS16760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9829_RS16765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9829_RS16770	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS16775	COG0456	acetyltransferase
D9829_RS16780	COG3829	transcription factor binding
D9829_RS16785	COG1509	lysine 2,3-aminomutase activity
D9829_RS16905	COG2801	Transposase and inactivated derivatives
D9829_RS16915	COG1404	Belongs to the peptidase S8 family
D9829_RS16920	COG0583	DNA-binding transcription factor activity
D9829_RS16925	COG0070	glutamate synthase
D9829_RS16925	COG0069	glutamate synthase activity
D9829_RS16925	COG0067	glutamate synthase
D9829_RS16930	COG0493	'glutamate synthase
D9829_RS16935	COG0861	Integral membrane protein TerC family
D9829_RS16955	COG2135	peptidase activity
D9829_RS16960	COG2807	transmembrane transport
D9829_RS16970	COG1312	Catalyzes the dehydration of D-mannonate
D9829_RS16975	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS16980	COG1802	Transcriptional regulator
D9829_RS16985	COG0671	phosphoesterase, PA-phosphatase related
D9829_RS16990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9829_RS17000	COG1011	Hydrolase
D9829_RS17010	COG0778	Nitroreductase
D9829_RS17045	COG0515	serine threonine protein kinase
D9829_RS17045	COG3266	domain, Protein
D9829_RS17050	COG4326	sporulation control protein
D9829_RS17060	COG1876	peptidase activity
D9829_RS17065	COG2217	Heavy metal translocating P-type atpase
D9829_RS17070	COG3409	Peptidoglycan-binding domain 1 protein
D9829_RS17070	COG0793	Belongs to the peptidase S41A family
D9829_RS17085	COG4876	unkown
D9829_RS17105	COG2340	Cysteine-rich secretory protein family
D9829_RS17120	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS17125	COG0534	Mate efflux family protein
D9829_RS17140	COG1228	amidohydrolase
D9829_RS17160	COG4667	esterase of the alpha-beta hydrolase superfamily
D9829_RS17165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS17180	COG3285	dna ligase
D9829_RS17180	COG1793	dna ligase
D9829_RS17185	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9829_RS17210	COG1113	amino acid transport
D9829_RS17220	COG1280	lysine exporter protein (LysE YggA)
D9829_RS17245	COG1607	acyl-coa hydrolase
D9829_RS17255	COG0024	Methionine aminopeptidase
D9829_RS17270	COG2801	Transposase and inactivated derivatives
D9829_RS17280	COG1349	DNA-binding transcription factor activity
D9829_RS17285	COG1105	Belongs to the carbohydrate kinase PfkB family
D9829_RS17290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS17290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9829_RS17290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9829_RS17300	COG2814	Major facilitator Superfamily
D9829_RS17305	COG2258	MOSC domain
D9829_RS17310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9829_RS17315	COG0512	Glutamine amidotransferase of anthranilate synthase
D9829_RS17315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9829_RS17345	COG2226	methyltransferase
D9829_RS17350	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
D9829_RS17360	COG0567	Dehydrogenase, E1 component
D9829_RS17365	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9829_RS17390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9829_RS17395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9829_RS17400	COG0488	(ABC) transporter
D9829_RS17405	COG0706	membrane insertase activity
D9829_RS17420	COG1268	BioY protein
D9829_RS17425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D9829_RS17440	COG2404	hydrolase activity, acting on ester bonds
D9829_RS17445	COG1686	Belongs to the peptidase S11 family
D9829_RS17450	COG4149	molybdate abc transporter
D9829_RS17455	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9829_RS17470	COG0488	(ABC) transporter
D9829_RS17475	COG1999	signal sequence binding
D9829_RS17480	COG2116	formate transmembrane transporter activity
D9829_RS17515	COG5002	protein histidine kinase activity
D9829_RS17520	COG3584	3D domain protein
D9829_RS17520	COG1388	LysM domain
D9829_RS17530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9829_RS17535	COG1295	ribonuclease BN
D9829_RS17545	COG2409	Drug exporters of the RND superfamily
D9829_RS17560	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
D9829_RS17580	COG3663	DNA glycosylase
D9829_RS17585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9829_RS17590	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS17605	COG1960	acyl-CoA dehydrogenase activity
D9829_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS17615	COG2390	Transcriptional regulator
D9829_RS17620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9829_RS17625	COG0646	methionine synthase
D9829_RS17625	COG1410	methionine synthase
D9829_RS17630	COG0646	methionine synthase
D9829_RS17630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9829_RS17635	COG0626	cystathionine gamma-synthase activity
D9829_RS17640	COG0626	cystathionine gamma-synthase activity
D9829_RS17645	COG0415	Belongs to the DNA photolyase family
D9829_RS17655	COG1609	Transcriptional regulator
D9829_RS17660	COG1175	transmembrane transport
D9829_RS17665	COG0395	ABC-type sugar transport system, permease component
D9829_RS17670	COG5578	integral membrane protein
D9829_RS17675	COG1653	transport
D9829_RS17690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9829_RS17700	COG1914	H( )-stimulated, divalent metal cation uptake system
D9829_RS17705	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9829_RS17710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9829_RS17715	COG1984	allophanate hydrolase subunit 2
D9829_RS17725	COG2814	Major facilitator Superfamily
D9829_RS17735	COG2602	Beta-lactamase
D9829_RS17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9829_RS17745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS17755	COG0516	GMP reductase activity
D9829_RS17760	COG1357	PFAM Pentapeptide repeats (8 copies)
D9829_RS17770	COG2323	membrane
D9829_RS17785	COG0701	Predicted permease
D9829_RS17800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9829_RS17810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS17815	COG1414	Transcriptional regulator
D9829_RS17820	COG0656	L-ascorbic acid biosynthetic process
D9829_RS17855	COG0730	response to heat
D9829_RS17885	COG1309	transcriptional regulator
D9829_RS17890	COG0477	Major facilitator Superfamily
D9829_RS17910	COG4844	belongs to the
D9829_RS17915	COG2814	Major facilitator Superfamily
D9829_RS17935	COG0346	lactoylglutathione lyase activity
D9829_RS17960	COG1396	sequence-specific DNA binding
D9829_RS17965	COG1272	protein, Hemolysin III
D9829_RS17970	COG1595	DNA-templated transcription, initiation
D9829_RS17980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9829_RS17985	COG1098	S1 RNA binding domain
D9829_RS17995	COG0492	ferredoxin-NADP+ reductase activity
D9829_RS18000	COG1120	ATPase activity
D9829_RS18005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9829_RS18010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS18015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS18040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9829_RS18055	COG1695	Transcriptional regulator
D9829_RS18105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9829_RS18110	COG0584	glycerophosphoryl diester phosphodiesterase
D9829_RS18125	COG3328	transposase activity
D9829_RS18135	COG0840	transmembrane signaling receptor activity
D9829_RS18140	COG4213	ABC transporter substrate-binding protein
D9829_RS18170	COG2814	Major facilitator Superfamily
D9829_RS18210	COG2205	protein histidine kinase activity
D9829_RS18210	COG0784	Response regulator, receiver
D9829_RS18215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9829_RS18220	COG5002	protein histidine kinase activity
D9829_RS18235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS18240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9829_RS18250	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9829_RS18270	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D9829_RS18270	COG2199	diguanylate cyclase activity
D9829_RS18275	COG3706	GGDEF domain
D9829_RS18275	COG4251	negative regulation of phosphorylation
D9829_RS18275	COG5001	Diguanylate cyclase
D9829_RS18275	COG2203	Gaf domain
D9829_RS18310	COG0657	acetylesterase activity
D9829_RS18310	COG2755	lipolytic protein G-D-S-L family
D9829_RS18315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D9829_RS18320	COG1595	DNA-templated transcription, initiation
D9829_RS18345	COG1309	transcriptional regulator
D9829_RS18365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9829_RS18370	COG0805	protein transport
D9829_RS18375	COG1393	Belongs to the ArsC family
D9829_RS18385	COG1959	2 iron, 2 sulfur cluster binding
D9829_RS18395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9829_RS18425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9829_RS18470	COG2721	sulfolactate sulfo-lyase activity
D9829_RS18475	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS18480	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS18490	COG3618	amidohydrolase
D9829_RS18495	COG4191	Histidine kinase
D9829_RS18500	COG2197	response regulator
D9829_RS18510	COG0737	Belongs to the 5'-nucleotidase family
D9829_RS18535	COG3773	Cell wall hydrolase
D9829_RS18540	COG1609	Transcriptional regulator
D9829_RS18545	COG1653	transport
D9829_RS18550	COG1175	transmembrane transport
D9829_RS18555	COG0395	ABC-type sugar transport system, permease component
D9829_RS18560	COG1486	melibiose metabolic process
D9829_RS18565	COG2329	Antibiotic biosynthesis monooxygenase
D9829_RS18585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9829_RS18585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9829_RS18590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9829_RS18600	COG1388	LysM domain
D9829_RS18600	COG3858	chitin binding
D9829_RS18605	COG2124	cytochrome p450
D9829_RS18635	COG1511	domain protein
D9829_RS18645	COG2207	Transcriptional regulator
D9829_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS18685	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS18720	COG1114	Component of the transport system for branched-chain amino acids
D9829_RS18725	COG2851	Citrate transporter
D9829_RS18730	COG3290	protein histidine kinase activity
D9829_RS18735	COG4565	transcriptional regulatory protein
D9829_RS18740	COG3181	Tripartite tricarboxylate transporter family receptor
D9829_RS18755	COG1131	(ABC) transporter
D9829_RS18790	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS18820	COG1621	beta-fructofuranosidase activity
D9829_RS18825	COG0531	amino acid
D9829_RS18855	COG0667	Aldo Keto reductase
D9829_RS18865	COG1846	Transcriptional regulator
D9829_RS18870	COG0456	acetyltransferase
D9829_RS18875	COG2808	Putative FMN-binding domain
D9829_RS18890	COG3858	chitin binding
D9829_RS18890	COG1388	LysM domain
D9829_RS18910	COG3848	Pyruvate phosphate dikinase
D9829_RS18910	COG0574	Belongs to the PEP-utilizing enzyme family
D9829_RS18920	COG3507	Belongs to the glycosyl hydrolase 43 family
D9829_RS18940	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9829_RS18960	COG1942	4-Oxalocrotonate Tautomerase
D9829_RS18965	COG0109	protoheme IX farnesyltransferase activity
D9829_RS18985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9829_RS19000	COG0346	lactoylglutathione lyase activity
D9829_RS19010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9829_RS19020	COG2072	flavoprotein involved in K transport
D9829_RS19025	COG0657	acetylesterase activity
D9829_RS19030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9829_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS19095	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS19115	COG1902	pentaerythritol trinitrate reductase activity
D9829_RS19130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9829_RS19135	COG0477	Major facilitator Superfamily
D9829_RS19155	COG4145	pantothenate transmembrane transporter activity
D9829_RS19195	COG0305	Participates in initiation and elongation during chromosome replication
D9829_RS19200	COG1522	sequence-specific DNA binding
D9829_RS19210	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS19215	COG3706	GGDEF domain
D9829_RS19235	COG0583	DNA-binding transcription factor activity
D9829_RS19240	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9829_RS19290	COG1595	DNA-templated transcription, initiation
D9829_RS19300	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS19310	COG2318	DinB family
D9829_RS19315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9829_RS19320	COG1522	sequence-specific DNA binding
D9829_RS19335	COG3655	Transcriptional regulator
D9829_RS19375	COG0747	negative chemotaxis
D9829_RS19380	COG0601	transmembrane transport
D9829_RS19385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9829_RS19390	COG0444	Belongs to the ABC transporter superfamily
D9829_RS19410	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9829_RS19460	COG0778	Nitroreductase
D9829_RS19490	COG4319	ketosteroid isomerase
D9829_RS19505	COG0346	lactoylglutathione lyase activity
D9829_RS19515	COG0697	spore germination
D9829_RS19520	COG2207	Transcriptional regulator
D9829_RS19520	COG1917	Cupin 2, conserved barrel domain protein
D9829_RS19525	COG2207	Transcriptional regulator
D9829_RS19560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS19600	COG0517	IMP dehydrogenase activity
D9829_RS19605	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS19615	COG3773	Cell wall hydrolase
D9829_RS19675	COG2226	methyltransferase
D9829_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS19725	COG1368	sulfuric ester hydrolase activity
D9829_RS19745	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D9829_RS19765	COG1131	(ABC) transporter
D9829_RS19780	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS19855	COG5444	nuclease activity
D9829_RS19865	COG5444	nuclease activity
D9829_RS19905	COG2205	protein histidine kinase activity
D9829_RS19910	COG3596	GTP binding
D9829_RS19915	COG1525	nuclease
D9829_RS19975	COG1486	melibiose metabolic process
D9829_RS20040	COG1846	Transcriptional regulator
D9829_RS20050	COG0346	lactoylglutathione lyase activity
D9829_RS20055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9829_RS20085	COG3764	Sortase (surface protein transpeptidase)
D9829_RS20090	COG2267	carboxylic ester hydrolase activity
D9829_RS20105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9829_RS20110	COG0154	amidase activity
D9829_RS20175	COG0018	arginyl-trna synthetase
D9829_RS20215	COG0697	spore germination
D9829_RS20240	COG1136	(ABC) transporter
D9829_RS20245	COG5002	protein histidine kinase activity
D9829_RS20245	COG3850	Histidine kinase
D9829_RS20250	COG0745	RESPONSE REGULATOR receiver
D9829_RS20255	COG0657	acetylesterase activity
D9829_RS20275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9829_RS20305	COG1388	LysM domain
D9829_RS20310	COG2222	sugar isomerase
D9829_RS20315	COG1653	transport
D9829_RS20320	COG1175	transmembrane transport
D9829_RS20325	COG0395	ABC-type sugar transport system, permease component
D9829_RS20330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS20335	COG2188	Transcriptional regulator
D9829_RS20345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9829_RS20350	COG0346	lactoylglutathione lyase activity
D9829_RS20370	COG0596	Alpha beta hydrolase
D9829_RS20375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9829_RS20395	COG1846	Transcriptional regulator
D9829_RS20400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS20420	COG0753	catalase activity
D9829_RS20425	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS20430	COG2814	Major facilitator Superfamily
D9829_RS20465	COG0604	alcohol dehydrogenase
D9829_RS20475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9829_RS20490	COG0861	Integral membrane protein TerC family
D9829_RS20505	COG1846	Transcriptional regulator
D9829_RS20515	COG1132	(ABC) transporter
D9829_RS20520	COG0412	Dienelactone hydrolase
D9829_RS20530	COG1737	Transcriptional regulator
D9829_RS20535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9829_RS20535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9829_RS20535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9829_RS20540	COG0383	alpha-mannosidase activity
D9829_RS20545	COG1929	Belongs to the glycerate kinase type-1 family
D9829_RS20550	COG1309	transcriptional regulator
D9829_RS20560	COG2860	membrane
D9829_RS20570	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS20600	COG0662	Cupin 2, conserved barrel domain protein
D9829_RS20605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9829_RS20610	COG1609	Transcriptional regulator
D9829_RS20615	COG0561	phosphatase activity
D9829_RS20625	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS20630	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS20670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9829_RS20715	COG0604	alcohol dehydrogenase
D9829_RS20730	COG3386	PFAM SMP-30 Gluconolaconase
D9829_RS20740	COG0768	penicillin binding
D9829_RS20750	COG0494	nUDIX hydrolase
D9829_RS20755	COG0776	regulation of translation
D9829_RS20800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9829_RS20810	COG0438	transferase activity, transferring glycosyl groups
D9829_RS20825	COG2814	Major facilitator Superfamily
D9829_RS20830	COG0789	Transcriptional regulator
D9829_RS20830	COG4978	Transcriptional regulator
D9829_RS20850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9829_RS20855	COG0583	DNA-binding transcription factor activity
D9829_RS20860	COG0384	phenazine biosynthesis protein PhzF
D9829_RS20900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9829_RS20900	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9829_RS20905	COG2318	DinB family
D9829_RS20910	COG2199	diguanylate cyclase activity
D9829_RS20910	COG2203	Gaf domain
D9829_RS20915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9829_RS20920	COG0546	phosphoglycolate phosphatase activity
D9829_RS20935	COG0281	malic enzyme
D9829_RS20945	COG0076	glutamate decarboxylase activity
D9829_RS20990	COG2814	Major facilitator Superfamily
D9829_RS21005	COG4209	transmembrane transport
D9829_RS21010	COG0395	ABC-type sugar transport system, permease component
D9829_RS21020	COG1609	Transcriptional regulator
D9829_RS21060	COG0726	polysaccharide deacetylase
D9829_RS21070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9829_RS21080	COG5566	PFAM Mor transcription activator
D9829_RS21105	COG2155	Conserved Protein
D9829_RS21110	COG2323	membrane
D9829_RS21115	COG0583	DNA-binding transcription factor activity
D9829_RS21140	COG1266	CAAX protease self-immunity
D9829_RS21145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9829_RS21150	COG1472	Belongs to the glycosyl hydrolase 3 family
D9829_RS21155	COG3876	Protein conserved in bacteria
D9829_RS21160	COG0561	phosphatase activity
D9829_RS21170	COG1737	Transcriptional regulator
D9829_RS21175	COG1263	PTS System
D9829_RS21175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS21185	COG2267	carboxylic ester hydrolase activity
D9829_RS21205	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9829_RS21205	COG0392	lysyltransferase activity
D9829_RS21235	COG1757	Na H antiporter
D9829_RS21260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9829_RS21265	COG0626	cystathionine gamma-synthase activity
D9829_RS21270	COG0730	response to heat
D9829_RS21275	COG0431	NADPH-dependent FMN reductase
D9829_RS21290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9829_RS21300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9829_RS21305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9829_RS21310	COG1959	2 iron, 2 sulfur cluster binding
D9829_RS21315	COG5583	Uncharacterized small protein (DUF2292)
D9829_RS21320	COG3048	D-serine ammonia-lyase activity
D9829_RS21340	COG1115	amino acid carrier protein
D9829_RS21345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9829_RS21355	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS21365	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D9829_RS21370	COG1378	Sugar-specific transcriptional regulator TrmB
D9829_RS21375	COG1573	uracil-dna glycosylase
D9829_RS21385	COG5416	Lipopolysaccharide assembly protein A domain
D9829_RS21390	COG1683	Conserved Protein
D9829_RS21410	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS21415	COG4873	Protein conserved in bacteria
D9829_RS21425	COG0456	acetyltransferase
D9829_RS21430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9829_RS21445	COG2259	Doxx family
D9829_RS21455	COG4677	pectinesterase activity
D9829_RS21460	COG2755	lipolytic protein G-D-S-L family
D9829_RS21490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9829_RS21495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9829_RS21515	COG0129	dihydroxy-acid dehydratase activity
D9829_RS21520	COG1114	Component of the transport system for branched-chain amino acids
D9829_RS21525	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS21540	COG5577	PFAM Coat F domain
D9829_RS21555	COG3973	AAA domain
D9829_RS21585	COG0534	Mate efflux family protein
D9829_RS21590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9829_RS21600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9829_RS21605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9829_RS21610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9829_RS21625	COG1404	Belongs to the peptidase S8 family
D9829_RS21640	COG1115	amino acid carrier protein
D9829_RS21645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9829_RS21650	COG0187	DNA topoisomerase II activity
D9829_RS21660	COG3973	AAA domain
D9829_RS21665	COG1832	CoA-binding protein
D9829_RS21680	COG4191	Histidine kinase
D9829_RS21685	COG2843	Capsule synthesis protein
D9829_RS21690	COG4841	protein insertion into membrane
D9829_RS21705	COG0824	Thioesterase
D9829_RS21710	COG0464	growth
D9829_RS21740	COG0583	DNA-binding transcription factor activity
D9829_RS21750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9829_RS21795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS21800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9829_RS21810	COG1183	phosphatidylcholine synthase activity
D9829_RS21815	COG2002	toxin-antitoxin pair type II binding
D9829_RS21825	COG0488	(ABC) transporter
D9829_RS21830	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
D9829_RS21835	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D9829_RS21845	COG0628	permease
D9829_RS21850	COG1418	mRNA catabolic process
D9829_RS21855	COG0300	oxidoreductase activity
D9829_RS21860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9829_RS21860	COG3153	acetyltransferase
D9829_RS21865	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9829_RS21875	COG0527	aspartate kinase activity
D9829_RS21880	COG0494	nUDIX hydrolase
D9829_RS21885	COG0561	phosphatase activity
D9829_RS21890	COG1027	Aspartate ammonia-lyase
D9829_RS21925	COG2197	response regulator
D9829_RS21930	COG2203	Gaf domain
D9829_RS21930	COG4585	Histidine kinase
D9829_RS21940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D9829_RS21950	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS21955	COG2197	response regulator
D9829_RS21960	COG4585	Histidine kinase
D9829_RS21965	COG3239	Fatty acid desaturase
D9829_RS21970	COG3832	glyoxalase III activity
D9829_RS21975	COG0733	neurotransmitter:sodium symporter activity
D9829_RS21980	COG3773	Cell wall hydrolase
D9829_RS21995	COG0590	tRNA wobble adenosine to inosine editing
D9829_RS22005	COG0702	epimerase
D9829_RS22010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9829_RS22030	COG1346	cytolysis
D9829_RS22035	COG0432	Pfam Uncharacterised protein family UPF0047
D9829_RS22050	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS22065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9829_RS22070	COG5002	protein histidine kinase activity
D9829_RS22075	COG2070	2-Nitropropane dioxygenase
D9829_RS22080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS22085	COG1403	HNH endonuclease
D9829_RS22100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9829_RS22105	COG0583	DNA-binding transcription factor activity
D9829_RS22110	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS22110	COG2202	Pas domain
D9829_RS22125	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS22130	COG0656	L-ascorbic acid biosynthetic process
D9829_RS22135	COG2814	Major facilitator Superfamily
D9829_RS22140	COG1733	regulation of RNA biosynthetic process
D9829_RS22155	COG0640	Transcriptional regulator
D9829_RS22170	COG3832	glyoxalase III activity
D9829_RS22180	COG0659	secondary active sulfate transmembrane transporter activity
D9829_RS22195	COG0741	lytic transglycosylase activity
D9829_RS22220	COG2388	GCN5-related N-acetyl-transferase
D9829_RS22225	COG0778	Nitroreductase
D9829_RS22235	COG0154	amidase activity
D9829_RS22240	COG2027	D-alanyl-D-alanine carboxypeptidase
D9829_RS22245	COG2409	Drug exporters of the RND superfamily
D9829_RS22255	COG1132	(ABC) transporter
D9829_RS22260	COG4989	oxidoreductase activity
D9829_RS22265	COG2154	pterin-4-alpha-carbinolamine dehydratase
D9829_RS22295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9829_RS22305	COG1054	Belongs to the UPF0176 family
D9829_RS22310	COG2608	mercury ion transmembrane transporter activity
D9829_RS22315	COG1132	(ABC) transporter
D9829_RS22320	COG1164	Oligoendopeptidase f
D9829_RS22330	COG1966	Carbon starvation protein
D9829_RS22340	COG0133	tryptophan synthase activity
D9829_RS22350	COG1657	PFAM Prenyltransferase squalene oxidase
D9829_RS22365	COG4948	Mandelate Racemase Muconate Lactonizing
D9829_RS22370	COG3314	Sporulation integral membrane protein YlbJ
D9829_RS22385	COG0322	excinuclease ABC activity
D9829_RS22395	COG2226	methyltransferase
D9829_RS22400	COG2226	methyltransferase
D9829_RS22405	COG1834	amidinotransferase
D9829_RS22435	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9829_RS22440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9829_RS22445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9829_RS22450	COG0693	protein deglycase activity
D9829_RS22455	COG0010	Belongs to the arginase family
D9829_RS22460	COG1228	amidohydrolase
D9829_RS22465	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D9829_RS22470	COG2986	histidine ammonia-lyase
D9829_RS22495	COG2271	Major facilitator Superfamily
D9829_RS22500	COG0277	FAD linked oxidase domain protein
D9829_RS22520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9829_RS22525	COG1116	anion transmembrane transporter activity
D9829_RS22530	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9829_RS22535	COG5002	protein histidine kinase activity
D9829_RS22540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9829_RS22545	COG2022	thiamine diphosphate biosynthetic process
D9829_RS22550	COG2104	thiamine diphosphate biosynthetic process
D9829_RS22555	COG0352	thiamine-phosphate diphosphorylase activity
D9829_RS22565	COG2066	Belongs to the glutaminase family
D9829_RS22575	COG0574	Belongs to the PEP-utilizing enzyme family
D9829_RS22575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9829_RS22580	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9829_RS22585	COG0708	Exodeoxyribonuclease III
D9829_RS22590	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9829_RS22595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9829_RS22595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9829_RS22600	COG0307	riboflavin synthase, alpha
D9829_RS22635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9829_RS22640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9829_RS22665	COG4873	Protein conserved in bacteria
D9829_RS22680	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9829_RS22680	COG2105	PFAM AIG2 family protein
D9829_RS22685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9829_RS22690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9829_RS22695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9829_RS22700	COG1024	Enoyl-CoA hydratase
D9829_RS22705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9829_RS22710	COG0511	ligase activity, forming carbon-carbon bonds
D9829_RS22715	COG0439	Biotin carboxylase
D9829_RS22720	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS22725	COG1960	acyl-CoA dehydrogenase activity
D9829_RS22730	COG1309	transcriptional regulator
D9829_RS22735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9829_RS22765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9829_RS22770	COG2304	oxidoreductase activity
D9829_RS22780	COG1063	alcohol dehydrogenase
D9829_RS22785	COG5577	PFAM Coat F domain
D9829_RS22800	COG5577	PFAM Coat F domain
D9829_RS22805	COG0670	Belongs to the BI1 family
D9829_RS22830	COG0740	serine-type endopeptidase activity
D9829_RS22845	COG1126	abc transporter atp-binding protein
D9829_RS22850	COG0765	amino acid transport
D9829_RS22860	COG4873	Protein conserved in bacteria
D9829_RS22865	COG2323	membrane
D9829_RS22870	COG2814	Major facilitator Superfamily
D9829_RS22875	COG3254	rhamnose metabolic process
D9829_RS22880	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9829_RS22890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS22915	COG0584	glycerophosphoryl diester phosphodiesterase
D9829_RS22920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9829_RS22930	COG0583	DNA-binding transcription factor activity
D9829_RS22935	COG1380	Effector of murein hydrolase LrgA
D9829_RS22940	COG1346	cytolysis
D9829_RS22975	COG2323	membrane
D9829_RS22980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9829_RS23000	COG2234	aminopeptidase activity
D9829_RS23020	COG2755	lipolytic protein G-D-S-L family
D9829_RS23020	COG3401	FG-GAP repeat protein
D9829_RS23025	COG3401	FG-GAP repeat protein
D9829_RS23030	COG0667	Aldo Keto reductase
D9829_RS23040	COG2340	Cysteine-rich secretory protein family
D9829_RS23060	COG1131	(ABC) transporter
D9829_RS23065	COG0561	phosphatase activity
D9829_RS23070	COG3546	catalase activity
D9829_RS23090	COG2270	Major facilitator Superfamily
D9829_RS23095	COG2223	nitrite transmembrane transporter activity
D9829_RS23110	COG0697	spore germination
D9829_RS23115	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D9829_RS23130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS23145	COG0385	Bile acid
D9829_RS23150	COG0352	thiamine-phosphate diphosphorylase activity
D9829_RS23155	COG0351	phosphomethylpyrimidine kinase
D9829_RS23160	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9829_RS23165	COG5434	Belongs to the glycosyl hydrolase 28 family
D9829_RS23170	COG2746	aminoglycoside 3-N-acetyltransferase activity
D9829_RS23175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9829_RS23180	COG0765	amino acid transport
D9829_RS23185	COG1126	abc transporter atp-binding protein
D9829_RS23195	COG4129	membrane
D9829_RS23200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS23240	COG1864	DNA RNA non-specific endonuclease
D9829_RS23240	COG3591	Belongs to the peptidase S1B family
D9829_RS23260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9829_RS23265	COG0436	Aminotransferase
D9829_RS23290	COG0697	spore germination
D9829_RS23295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9829_RS23300	COG5522	Integral membrane protein (intg_mem_TP0381)
D9829_RS23305	COG2124	cytochrome p450
D9829_RS23325	COG1408	metallophosphoesterase
D9829_RS23330	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D9829_RS23340	COG1247	-acetyltransferase
D9829_RS23345	COG1595	DNA-templated transcription, initiation
D9829_RS23355	COG1131	(ABC) transporter
D9829_RS23360	COG1725	Transcriptional regulator
D9829_RS23365	COG2720	vancomycin resistance protein
D9829_RS23370	COG1757	Na H antiporter
D9829_RS23375	COG0084	hydrolase, TatD family'
D9829_RS23380	COG0768	penicillin binding
D9829_RS23390	COG0584	glycerophosphoryl diester phosphodiesterase
D9829_RS23395	COG0561	phosphatase activity
D9829_RS23400	COG1876	peptidase activity
D9829_RS23430	COG0683	leucine binding
D9829_RS23445	COG0346	lactoylglutathione lyase activity
D9829_RS23455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9829_RS23460	COG0789	Transcriptional regulator
D9829_RS23465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9829_RS23515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9829_RS23530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D9829_RS23535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9829_RS23540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9829_RS23545	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS23550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9829_RS23570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9829_RS23585	COG0598	Magnesium transport protein CorA
D9829_RS23590	COG3546	catalase activity
D9829_RS23595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9829_RS23605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9829_RS23610	COG1131	(ABC) transporter
D9829_RS23615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9829_RS23625	COG3546	catalase activity
D9829_RS23635	COG0463	Glycosyl transferase, family 2
D9829_RS23645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9829_RS23660	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
D9829_RS23665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9829_RS23670	COG1199	ATP-dependent helicase activity
D9829_RS23695	COG0517	IMP dehydrogenase activity
D9829_RS23705	COG0346	lactoylglutathione lyase activity
D9829_RS23710	COG1388	LysM domain
D9829_RS23710	COG0791	NLP P60 protein
D9829_RS23715	COG2323	membrane
D9829_RS23730	COG5146	pantothenate kinase activity
D9829_RS23740	COG0419	ATPase involved in DNA repair
D9829_RS23755	COG0735	belongs to the Fur family
D9829_RS23760	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9829_RS23765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9829_RS23770	COG2351	hydroxyisourate hydrolase activity
D9829_RS23785	COG2508	Transcriptional regulator
D9829_RS23800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9829_RS23815	COG0028	Belongs to the TPP enzyme family
D9829_RS23825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9829_RS23830	COG3959	Transketolase, thiamine diphosphate binding domain
D9829_RS23835	COG1414	Transcriptional regulator
D9829_RS23840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9829_RS23850	COG0726	polysaccharide deacetylase
D9829_RS23860	COG5577	PFAM Coat F domain
D9829_RS23865	COG1368	sulfuric ester hydrolase activity
D9829_RS23875	COG1119	ATPase activity
D9829_RS23880	COG0861	Integral membrane protein TerC family
D9829_RS23885	COG0730	response to heat
D9829_RS23895	COG2814	Major facilitator Superfamily
D9829_RS23910	COG0175	sulfate reduction
D9829_RS23915	COG2046	Belongs to the sulfate adenylyltransferase family
D9829_RS23920	COG0529	Catalyzes the synthesis of activated sulfate
D9829_RS23925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9829_RS23940	COG1131	(ABC) transporter
D9829_RS23945	COG1309	transcriptional regulator
D9829_RS23950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9829_RS23965	COG2720	vancomycin resistance protein
D9829_RS23975	COG0720	synthase
D9829_RS23985	COG0385	Bile acid
D9829_RS24000	COG1305	Transglutaminase-like
D9829_RS24010	COG2308	Evidence 4 Homologs of previously reported genes of
D9829_RS24025	COG1595	DNA-templated transcription, initiation
D9829_RS24030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9829_RS24045	COG3250	beta-galactosidase activity
D9829_RS24055	COG0395	ABC-type sugar transport system, permease component
D9829_RS24060	COG4209	transmembrane transport
D9829_RS24070	COG1609	Transcriptional regulator
D9829_RS24075	COG0019	diaminopimelate decarboxylase activity
D9829_RS24085	COG4264	IucA IucC family
D9829_RS24090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS24090	COG2190	(PTS) system
D9829_RS24090	COG1263	PTS System
D9829_RS24095	COG2723	6-phospho-beta-galactosidase activity
D9829_RS24105	COG2112	serine threonine protein kinase
D9829_RS24135	COG2211	Major facilitator Superfamily
D9829_RS24140	COG1940	carbohydrate kinase activity
D9829_RS24155	COG3250	beta-galactosidase activity
D9829_RS24165	COG0395	ABC-type sugar transport system, permease component
D9829_RS24170	COG1175	transmembrane transport
D9829_RS24180	COG4753	response regulator
D9829_RS24180	COG2207	Transcriptional regulator
D9829_RS24185	COG2972	Histidine kinase
D9829_RS24190	COG1472	Belongs to the glycosyl hydrolase 3 family
D9829_RS24245	COG0383	alpha-mannosidase activity
D9829_RS24255	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS24260	COG1940	carbohydrate kinase activity
D9829_RS24265	COG2723	6-phospho-beta-galactosidase activity
D9829_RS24270	COG2201	protein-glutamate methylesterase activity
D9829_RS24275	COG2972	Histidine kinase
D9829_RS24280	COG1653	transport
D9829_RS24285	COG0395	ABC-type sugar transport system, permease component
D9829_RS24290	COG4209	transmembrane transport
D9829_RS24295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D9829_RS24295	COG3291	Pkd domain containing protein
D9829_RS24315	COG3711	transcriptional antiterminator
D9829_RS24340	COG0383	alpha-mannosidase activity
D9829_RS24370	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS24380	COG1609	Transcriptional regulator
D9829_RS24385	COG1653	transport
D9829_RS24390	COG0395	ABC-type sugar transport system, permease component
D9829_RS24395	COG4209	transmembrane transport
D9829_RS24400	COG1063	alcohol dehydrogenase
D9829_RS24420	COG2814	Major facilitator Superfamily
D9829_RS24430	COG1120	ATPase activity
D9829_RS24435	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS24440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9829_RS24465	COG1764	response to oxidative stress
D9829_RS24470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS24480	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9829_RS24490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9829_RS24495	COG1408	metallophosphoesterase
D9829_RS24500	COG0726	polysaccharide deacetylase
D9829_RS24505	COG2188	Transcriptional regulator
D9829_RS24510	COG0366	Alpha amylase catalytic
D9829_RS24515	COG0366	Alpha amylase catalytic
D9829_RS24520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS24520	COG1263	PTS System
D9829_RS24530	COG0477	Major facilitator Superfamily
D9829_RS24540	COG4677	pectinesterase activity
D9829_RS24545	COG1073	alpha beta
D9829_RS24555	COG1653	transport
D9829_RS24560	COG5578	integral membrane protein
D9829_RS24565	COG4209	transmembrane transport
D9829_RS24570	COG0395	ABC-type sugar transport system, permease component
D9829_RS24575	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9829_RS24580	COG2207	Transcriptional regulator
D9829_RS24585	COG2755	lipolytic protein G-D-S-L family
D9829_RS24590	COG1653	transport
D9829_RS24600	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9829_RS24605	COG3507	Belongs to the glycosyl hydrolase 43 family
D9829_RS24610	COG2755	lipolytic protein G-D-S-L family
D9829_RS24610	COG0657	acetylesterase activity
D9829_RS24625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9829_RS24635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9829_RS24640	COG3383	formate dehydrogenase (NAD+) activity
D9829_RS24645	COG2427	Protein of unknown function (DUF1641)
D9829_RS24660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9829_RS24665	COG2755	lipolytic protein G-D-S-L family
D9829_RS24685	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS24710	COG0693	protein deglycase activity
D9829_RS24725	COG0667	Aldo Keto reductase
D9829_RS24730	COG0667	Aldo Keto reductase
D9829_RS24760	COG0673	inositol 2-dehydrogenase activity
D9829_RS24765	COG1082	Xylose isomerase domain protein TIM barrel
D9829_RS24770	COG0395	ABC-type sugar transport system, permease component
D9829_RS24775	COG1175	transmembrane transport
D9829_RS24780	COG1653	transport
D9829_RS24810	COG1940	carbohydrate kinase activity
D9829_RS24815	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9829_RS24845	COG5578	integral membrane protein
D9829_RS24870	COG2972	Histidine kinase
D9829_RS24880	COG0395	ABC-type sugar transport system, permease component
D9829_RS24885	COG1175	transmembrane transport
D9829_RS24915	COG0523	cobalamin synthesis protein
D9829_RS24930	COG0534	Mate efflux family protein
D9829_RS24935	COG4608	Belongs to the ABC transporter superfamily
D9829_RS24940	COG0444	Belongs to the ABC transporter superfamily
D9829_RS24955	COG4166	transmembrane transport
D9829_RS25000	COG3708	Transcriptional regulator
D9829_RS25000	COG2207	Transcriptional regulator
D9829_RS25005	COG2186	Transcriptional regulator
D9829_RS25010	COG1929	Belongs to the glycerate kinase type-1 family
D9829_RS25015	COG2084	Dehydrogenase
D9829_RS25020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9829_RS25030	COG2271	Major facilitator Superfamily
D9829_RS25055	COG2608	mercury ion transmembrane transporter activity
D9829_RS25070	COG1363	Peptidase, m42
D9829_RS25080	COG4895	conserved protein (DUF2196)
D9829_RS25085	COG4193	domain, Protein
D9829_RS25090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9829_RS25100	COG5577	PFAM Coat F domain
D9829_RS25110	COG0386	Belongs to the glutathione peroxidase family
D9829_RS25115	COG2226	methyltransferase
D9829_RS25155	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS25160	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS25165	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS25185	COG0110	maltose O-acetyltransferase activity
D9829_RS25245	COG2814	Major facilitator Superfamily
D9829_RS25270	COG0456	acetyltransferase
D9829_RS25275	COG3852	Histidine kinase
D9829_RS25290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9829_RS25300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9829_RS25315	COG0745	RESPONSE REGULATOR receiver
D9829_RS25320	COG2205	protein histidine kinase activity
D9829_RS25325	COG1136	(ABC) transporter
D9829_RS25330	COG0577	efflux transmembrane transporter activity
D9829_RS25355	COG1595	DNA-templated transcription, initiation
D9829_RS25370	COG1278	Cold shock
D9829_RS25375	COG0772	Belongs to the SEDS family
D9829_RS25385	COG1396	sequence-specific DNA binding
D9829_RS25395	COG1917	Cupin 2, conserved barrel domain protein
D9829_RS25395	COG2207	Transcriptional regulator
D9829_RS25405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9829_RS25440	COG1070	Carbohydrate kinase
D9829_RS25540	COG2723	6-phospho-beta-galactosidase activity
D9829_RS25545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS25545	COG2190	(PTS) system
D9829_RS25545	COG1263	PTS System
D9829_RS25550	COG3711	transcriptional antiterminator
D9829_RS25555	COG0531	amino acid
D9829_RS25565	COG3665	Urea carboxylase-associated protein
D9829_RS25570	COG0439	Biotin carboxylase
D9829_RS25585	COG2169	Transcriptional regulator
D9829_RS25605	COG0395	ABC-type sugar transport system, permease component
D9829_RS25610	COG4209	transmembrane transport
D9829_RS25620	COG2972	Histidine kinase
D9829_RS25625	COG4753	response regulator
D9829_RS25625	COG2207	Transcriptional regulator
D9829_RS25630	COG5578	integral membrane protein
D9829_RS25640	COG1486	melibiose metabolic process
D9829_RS25650	COG3940	Belongs to the glycosyl hydrolase 43 family
D9829_RS25655	COG0823	Involved in the tonB-independent uptake of proteins
D9829_RS25660	COG1653	transport
D9829_RS25680	COG1278	Cold shock
D9829_RS25695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9829_RS25715	COG0673	inositol 2-dehydrogenase activity
D9829_RS25720	COG1653	transport
D9829_RS25725	COG0395	ABC-type sugar transport system, permease component
D9829_RS25730	COG4209	transmembrane transport
D9829_RS25780	COG4977	sequence-specific DNA binding
D9829_RS25805	COG1486	melibiose metabolic process
D9829_RS25815	COG0475	glutathione-regulated potassium exporter activity
D9829_RS25825	COG0129	dihydroxy-acid dehydratase activity
D9829_RS25830	COG2233	PERMEase
D9829_RS25845	COG1621	beta-fructofuranosidase activity
D9829_RS25850	COG1621	beta-fructofuranosidase activity
D9829_RS25855	COG1653	transport
D9829_RS25860	COG4753	response regulator
D9829_RS25860	COG2207	Transcriptional regulator
D9829_RS25865	COG2972	Histidine kinase
D9829_RS25880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9829_RS25885	COG1621	beta-fructofuranosidase activity
D9829_RS25895	COG0395	ABC-type sugar transport system, permease component
D9829_RS25900	COG4209	transmembrane transport
D9829_RS25910	COG4753	response regulator
D9829_RS25910	COG2207	Transcriptional regulator
D9829_RS25915	COG3275	phosphorelay sensor kinase activity
D9829_RS25925	COG0768	penicillin binding
D9829_RS25930	COG0840	transmembrane signaling receptor activity
D9829_RS25935	COG3250	beta-galactosidase activity
D9829_RS25950	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9829_RS25955	COG1129	ABC transporter
D9829_RS25960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9829_RS25960	COG2207	Transcriptional regulator
D9829_RS25965	COG2972	Histidine kinase
D9829_RS25990	COG0674	pyruvate-flavodoxin oxidoreductase activity
D9829_RS25995	COG0281	malic enzyme
D9829_RS26025	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D9829_RS26030	COG0105	UTP biosynthetic process
D9829_RS26040	COG4122	O-methyltransferase activity
D9829_RS26055	COG1175	transmembrane transport
D9829_RS26060	COG0395	ABC-type sugar transport system, permease component
D9829_RS26075	COG0673	inositol 2-dehydrogenase activity
D9829_RS26090	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
D9829_RS26095	COG1940	carbohydrate kinase activity
D9829_RS26110	COG3458	cephalosporin-C deacetylase activity
D9829_RS26140	COG2003	Belongs to the UPF0758 family
D9829_RS26160	COG0515	serine threonine protein kinase
D9829_RS26170	COG0671	phosphoesterase, PA-phosphatase related
D9829_RS26180	COG2326	polyphosphate kinase activity
D9829_RS26200	COG1175	transmembrane transport
D9829_RS26205	COG3833	ABC-type maltose transport systems, permease component
D9829_RS26215	COG1609	Transcriptional regulator
D9829_RS26230	COG4209	transmembrane transport
D9829_RS26235	COG0395	ABC-type sugar transport system, permease component
D9829_RS26240	COG1653	transport
D9829_RS26250	COG3275	phosphorelay sensor kinase activity
D9829_RS26295	COG1902	pentaerythritol trinitrate reductase activity
D9829_RS26300	COG1733	regulation of RNA biosynthetic process
D9829_RS26305	COG2814	Major facilitator Superfamily
D9829_RS26315	COG1733	regulation of RNA biosynthetic process
D9829_RS26355	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS26360	COG1366	Belongs to the anti-sigma-factor antagonist family
D9829_RS26365	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9829_RS26385	COG4974	Belongs to the 'phage' integrase family
D9829_RS26405	COG0730	response to heat
D9829_RS26415	COG2814	Major facilitator Superfamily
D9829_RS26420	COG2723	6-phospho-beta-galactosidase activity
D9829_RS26425	COG2190	(PTS) system
D9829_RS26425	COG1263	PTS System
D9829_RS26425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS26430	COG3711	transcriptional antiterminator
D9829_RS26470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D9829_RS26475	COG0732	type I restriction modification DNA specificity domain
D9829_RS26480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
D9829_RS26485	COG4974	Belongs to the 'phage' integrase family
D9829_RS26535	COG1131	(ABC) transporter
D9829_RS26540	COG1725	Transcriptional regulator
D9829_RS26550	COG1595	DNA-templated transcription, initiation
D9829_RS26565	COG1595	DNA-templated transcription, initiation
D9829_RS26585	COG2211	Major facilitator Superfamily
D9829_RS26595	COG4974	Belongs to the 'phage' integrase family
D9829_RS26620	COG1388	LysM domain
D9829_RS26620	COG0791	NLP P60 protein
D9829_RS26625	COG1388	LysM domain
D9829_RS26625	COG0791	NLP P60 protein
D9829_RS26630	COG4227	nucleotidyltransferase activity
D9829_RS26695	COG1733	regulation of RNA biosynthetic process
D9829_RS26700	COG0640	Transcriptional regulator
D9829_RS26705	COG0477	Major facilitator Superfamily
D9829_RS26710	COG0702	epimerase
D9829_RS26775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9829_RS26915	COG2801	Transposase and inactivated derivatives
D9829_RS26920	COG2801	Transposase and inactivated derivatives
D9829_RS26950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9829_RS26955	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS26960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9829_RS26970	COG3118	belongs to the thioredoxin family
D9829_RS26975	COG1725	Transcriptional regulator
D9829_RS27015	COG1378	Sugar-specific transcriptional regulator TrmB
D9829_RS27020	COG1280	lysine exporter protein (LysE YggA)
D9829_RS27050	COG2217	Heavy metal translocating P-type atpase
D9829_RS27055	COG2608	mercury ion transmembrane transporter activity
D9829_RS27075	COG2608	mercury ion transmembrane transporter activity
D9829_RS27105	COG0730	response to heat
D9829_RS27110	COG0425	Belongs to the sulfur carrier protein TusA family
D9829_RS27115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9829_RS27115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9829_RS27130	COG0425	Belongs to the sulfur carrier protein TusA family
D9829_RS27130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9829_RS27145	COG2210	Belongs to the sulfur carrier protein TusA family
D9829_RS27150	COG1937	Protein conserved in bacteria
D9829_RS27160	COG0785	Cytochrome C biogenesis protein
D9829_RS27165	COG0745	RESPONSE REGULATOR receiver
D9829_RS27170	COG5002	protein histidine kinase activity
D9829_RS27185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS27195	COG2197	response regulator
D9829_RS27200	COG4585	Histidine kinase
D9829_RS27235	COG3119	arylsulfatase activity
D9829_RS27240	COG2211	Major facilitator Superfamily
D9829_RS27250	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D9829_RS27255	COG0583	DNA-binding transcription factor activity
D9829_RS27260	COG2723	6-phospho-beta-galactosidase activity
D9829_RS27275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9829_RS27305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9829_RS27325	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9829_RS27330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9829_RS27335	COG1733	regulation of RNA biosynthetic process
D9829_RS27370	COG2217	Heavy metal translocating P-type atpase
D9829_RS27375	COG2608	mercury ion transmembrane transporter activity
D9829_RS27390	COG2814	Major facilitator Superfamily
D9829_RS27400	COG0477	Major facilitator Superfamily
D9829_RS27405	COG2723	6-phospho-beta-galactosidase activity
D9829_RS27410	COG2190	(PTS) system
D9829_RS27410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS27410	COG1263	PTS System
D9829_RS27415	COG3711	transcriptional antiterminator
D9829_RS27420	COG1522	sequence-specific DNA binding
D9829_RS27425	COG1335	isochorismatase
D9829_RS27435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9829_RS27445	COG1846	Transcriptional regulator
D9829_RS27465	COG0492	ferredoxin-NADP+ reductase activity
D9829_RS27475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9829_RS27475	COG2190	(PTS) system
D9829_RS27475	COG1263	PTS System
D9829_RS27520	COG0183	Belongs to the thiolase family
D9829_RS27535	COG1414	Transcriptional regulator
D9829_RS27565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9829_RS27570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9829_RS27615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9829_RS27630	COG3321	synthase
D9829_RS27630	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS27630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9829_RS27630	COG0318	PFAM AMP-dependent synthetase and ligase
D9829_RS27630	COG0300	oxidoreductase activity
D9829_RS27650	COG2002	toxin-antitoxin pair type II binding
D9829_RS27685	COG1476	TRANSCRIPTIONal
D9829_RS27695	COG4974	Belongs to the 'phage' integrase family
D9829_RS27865	COG1929	Belongs to the glycerate kinase type-1 family
D9829_RS27870	COG2610	gluconate transmembrane transporter activity
D9829_RS27875	COG3835	regulator
D9829_RS27880	COG0698	ribose 5-phosphate isomerase
D9829_RS27885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9829_RS27890	COG1012	belongs to the aldehyde dehydrogenase family
D9829_RS27900	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9829_RS27905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D9829_RS27910	COG1609	Transcriptional regulator
D9829_RS27915	COG0395	ABC-type sugar transport system, permease component
D9829_RS27920	COG1175	transmembrane transport
D9829_RS27925	COG1653	transport
D9829_RS27940	COG0697	spore germination
D9829_RS27945	COG2271	Major facilitator Superfamily
D9829_RS27955	COG3275	phosphorelay sensor kinase activity
D9829_RS27965	COG2801	Transposase and inactivated derivatives
D9829_RS27970	COG0673	inositol 2-dehydrogenase activity
D9829_RS27980	COG0673	inositol 2-dehydrogenase activity
D9829_RS27990	COG1653	transport
D9829_RS27995	COG0395	ABC-type sugar transport system, permease component
D9829_RS28000	COG4209	transmembrane transport
D9829_RS28005	COG5000	phosphorelay sensor kinase activity
D9829_RS28020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D9829_RS28025	COG0248	Ppx GppA phosphatase
D9829_RS28040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9829_RS28045	COG0640	Transcriptional regulator
D9829_RS28050	COG3639	organic phosphonate transmembrane transporter activity
D9829_RS28055	COG3639	organic phosphonate transmembrane transporter activity
D9829_RS28060	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
D9829_RS28070	COG4778	phosphonate C-P lyase system protein PhnL
D9829_RS28075	COG3454	Phosphonate metabolism
D9829_RS28080	COG4107	phosphonate C-P lyase system protein PhnK
D9829_RS28085	COG3627	carbon phosphorus lyase activity
D9829_RS28105	COG1609	Transcriptional regulator
D9829_RS28115	COG0613	PHP domain protein
D9829_RS28120	COG3540	Alkaline phosphatase
D9829_RS28140	COG4191	Histidine kinase
D9829_RS28330	COG1595	DNA-templated transcription, initiation
D9829_RS28340	COG1595	DNA-templated transcription, initiation
D9829_RS28350	COG1278	Cold shock
D9829_RS28365	COG2002	toxin-antitoxin pair type II binding
D9829_RS28370	COG2333	competence protein COMEC
D9829_RS28370	COG0658	competence protein
D9829_RS28385	COG1793	dna ligase
D9829_RS28390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9829_RS28400	COG1028	Short-chain dehydrogenase reductase Sdr
D9829_RS28405	COG1733	regulation of RNA biosynthetic process
D9829_RS28480	COG1192	Involved in chromosome partitioning
D9829_RS28530	COG0741	lytic transglycosylase activity
D9829_RS28530	COG0791	NLP P60 protein
D9829_RS28570	COG0673	inositol 2-dehydrogenase activity