locus-tag	class	description
MW696_RS00015	COG1392	Phosphate transport regulator
MW696_RS00020	COG0405	Gamma-glutamyltransferase
MW696_RS00025	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MW696_RS00035	COG4208	sulfate ABC transporter
MW696_RS00045	COG5578	integral membrane protein
MW696_RS00050	COG2972	Histidine kinase
MW696_RS00055	COG2207	Transcriptional regulator
MW696_RS00055	COG4753	response regulator
MW696_RS00060	COG1653	transport
MW696_RS00065	COG1175	transmembrane transport
MW696_RS00070	COG0395	ABC-type sugar transport system, permease component
MW696_RS00075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MW696_RS00080	COG2207	Transcriptional regulator
MW696_RS00085	COG2755	lipolytic protein G-D-S-L family
MW696_RS00095	COG5578	integral membrane protein
MW696_RS00100	COG3401	FG-GAP repeat protein
MW696_RS00105	COG3401	FG-GAP repeat protein
MW696_RS00110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS00120	COG2755	lipolytic protein G-D-S-L family
MW696_RS00125	COG1874	Beta-galactosidase
MW696_RS00135	COG1653	transport
MW696_RS00140	COG4209	transmembrane transport
MW696_RS00145	COG0395	ABC-type sugar transport system, permease component
MW696_RS00150	COG0531	amino acid
MW696_RS00155	COG0346	lactoylglutathione lyase activity
MW696_RS00160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_RS00165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MW696_RS00170	COG2362	D-Aminopeptidase
MW696_RS00175	COG0601	transmembrane transport
MW696_RS00180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_RS00185	COG0444	Belongs to the ABC transporter superfamily
MW696_RS00190	COG4166	transmembrane transport
MW696_RS00195	COG1619	proteins homologs of microcin C7 resistance protein MccF
MW696_RS00200	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_RS00205	COG0791	NLP P60 protein
MW696_RS00210	COG4608	Belongs to the ABC transporter superfamily
MW696_RS00225	COG1834	amidinotransferase
MW696_RS00230	COG1607	acyl-coa hydrolase
MW696_RS00235	COG3866	Pectate lyase
MW696_RS00240	COG2318	DinB family
MW696_RS00245	COG2076	Multidrug Resistance protein
MW696_RS00250	COG2076	Multidrug Resistance protein
MW696_RS00255	COG0788	formyltetrahydrofolate deformylase activity
MW696_RS00260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MW696_RS00265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MW696_RS00270	COG1764	response to oxidative stress
MW696_RS00275	COG1846	Transcriptional regulator
MW696_RS00280	COG1764	response to oxidative stress
MW696_RS00290	COG0590	tRNA wobble adenosine to inosine editing
MW696_RS00310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MW696_RS00315	COG1404	Belongs to the peptidase S8 family
MW696_RS00325	COG2239	Acts as a magnesium transporter
MW696_RS00335	COG0789	Transcriptional regulator
MW696_RS00350	COG1846	Transcriptional regulator
MW696_RS00355	COG1793	dna ligase
MW696_RS00355	COG3285	dna ligase
MW696_RS00360	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MW696_RS00365	COG3300	MHYT domain
MW696_RS00365	COG5001	Diguanylate cyclase
MW696_RS00370	COG0586	Pfam SNARE associated Golgi protein
MW696_RS00375	COG0861	Integral membrane protein TerC family
MW696_RS00380	COG1191	sigma factor activity
MW696_RS00400	COG0501	Belongs to the peptidase M48B family
MW696_RS00405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MW696_RS00410	COG0768	penicillin binding
MW696_RS00425	COG3594	Acyltransferase
MW696_RS00430	COG5002	protein histidine kinase activity
MW696_RS00435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MW696_RS00445	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MW696_RS00450	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MW696_RS00455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MW696_RS00460	COG0436	Aminotransferase
MW696_RS00465	COG1850	ribulose-bisphosphate carboxylase activity
MW696_RS00470	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MW696_RS00470	COG0235	Class ii aldolase
MW696_RS00475	COG0235	Class ii aldolase
MW696_RS00475	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MW696_RS00480	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MW696_RS00485	COG0346	lactoylglutathione lyase activity
MW696_RS00490	COG3339	Conserved Protein
MW696_RS00500	COG3852	Histidine kinase
MW696_RS00505	COG1846	Transcriptional regulator
MW696_RS00510	COG1360	Flagellar Motor Protein
MW696_RS00515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MW696_RS00520	COG0542	response to heat
MW696_RS00525	COG3949	Membrane
MW696_RS00530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MW696_RS00535	COG0720	synthase
MW696_RS00540	COG0602	queuosine metabolic process
MW696_RS00545	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MW696_RS00560	COG0456	acetyltransferase
MW696_RS00580	COG4873	Protein conserved in bacteria
MW696_RS00590	COG3773	Cell wall hydrolase
MW696_RS00595	COG2244	polysaccharide biosynthetic process
MW696_RS00600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS00605	COG2217	Heavy metal translocating P-type atpase
MW696_RS00610	COG0006	proline dipeptidase activity
MW696_RS00615	COG1609	Transcriptional regulator
MW696_RS00620	COG3711	transcriptional antiterminator
MW696_RS00625	COG1263	PTS System
MW696_RS00625	COG2190	(PTS) system
MW696_RS00625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS00630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS00635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MW696_RS00645	COG1533	DNA photolyase activity
MW696_RS00650	COG0456	acetyltransferase
MW696_RS00655	COG0840	transmembrane signaling receptor activity
MW696_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS00665	COG2084	Dehydrogenase
MW696_RS00670	COG2340	Cysteine-rich secretory protein family
MW696_RS00675	COG0768	penicillin binding
MW696_RS00680	COG4191	Histidine kinase
MW696_RS00685	COG0436	Aminotransferase
MW696_RS00705	COG0784	Response regulator, receiver
MW696_RS00705	COG0835	chemotaxis
MW696_RS00715	COG2814	Major facilitator Superfamily
MW696_RS00720	COG1376	ErfK ybiS ycfS ynhG family protein
MW696_RS00725	COG1408	metallophosphoesterase
MW696_RS00730	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS00735	COG2200	EAL domain
MW696_RS00740	COG4703	Protein of unknown function (DUF1797)
MW696_RS00750	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MW696_RS00760	COG0517	IMP dehydrogenase activity
MW696_RS00765	COG0583	DNA-binding transcription factor activity
MW696_RS00770	COG0716	FMN binding
MW696_RS00780	COG0716	FMN binding
MW696_RS00785	COG2171	N-acyltransferase activity
MW696_RS00790	COG1473	amidohydrolase
MW696_RS00800	COG0450	alkyl hydroperoxide reductase
MW696_RS00805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS00820	COG0746	molybdenum cofactor guanylyltransferase activity
MW696_RS00825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MW696_RS00830	COG0303	'Molybdopterin
MW696_RS00835	COG1763	Mo-molybdopterin cofactor biosynthetic process
MW696_RS00840	COG0314	molybdopterin synthase activity
MW696_RS00845	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MW696_RS00855	COG1132	(ABC) transporter
MW696_RS00860	COG1132	(ABC) transporter
MW696_RS00870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MW696_RS00875	COG1136	(ABC) transporter
MW696_RS00880	COG0577	efflux transmembrane transporter activity
MW696_RS00890	COG1349	DNA-binding transcription factor activity
MW696_RS00895	COG1105	Belongs to the carbohydrate kinase PfkB family
MW696_RS00900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS00900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_RS00900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_RS00920	COG0488	(ABC) transporter
MW696_RS00925	COG2309	aminopeptidase activity
MW696_RS00935	COG1077	Cell shape determining protein MreB Mrl
MW696_RS00940	COG2002	toxin-antitoxin pair type II binding
MW696_RS00945	COG3852	Histidine kinase
MW696_RS00950	COG0569	domain protein
MW696_RS00955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MW696_RS00960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MW696_RS00965	COG5503	Protein of unknown function (DUF1447)
MW696_RS00970	COG0561	phosphatase activity
MW696_RS00975	COG0242	peptide deformylase activity
MW696_RS00985	COG0497	DNA recombination
MW696_RS00990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MW696_RS00995	COG0022	dehydrogenase e1 component
MW696_RS01000	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_RS01005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MW696_RS01010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS01020	COG1982	Orn Lys Arg decarboxylase major
MW696_RS01025	COG4476	Belongs to the UPF0223 family
MW696_RS01030	COG4493	Belongs to the UPF0637 family
MW696_RS01040	COG0483	inositol monophosphate 1-phosphatase activity
MW696_RS01060	COG1217	gtp-binding protein TYPA
MW696_RS01070	COG1846	Transcriptional regulator
MW696_RS01075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MW696_RS01080	COG4896	Protein conserved in bacteria
MW696_RS01090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MW696_RS01095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MW696_RS01100	COG2066	Belongs to the glutaminase family
MW696_RS01105	COG4838	Belongs to the UPF0358 family
MW696_RS01110	COG0772	Belongs to the SEDS family
MW696_RS01115	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MW696_RS01120	COG1612	heme a metabolic process
MW696_RS01125	COG0109	protoheme IX farnesyltransferase activity
MW696_RS01130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MW696_RS01130	COG2010	Cytochrome c
MW696_RS01135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MW696_RS01140	COG1845	cytochrome c oxidase, subunit III
MW696_RS01145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MW696_RS01150	COG3336	cytochrome c oxidase
MW696_RS01160	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MW696_RS01165	COG2340	Cysteine-rich secretory protein family
MW696_RS01190	COG3679	Belongs to the UPF0342 family
MW696_RS01195	COG4471	UPF0298 protein
MW696_RS01200	COG0742	ribosomal rna small subunit methyltransferase
MW696_RS01205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MW696_RS01210	COG3314	Sporulation integral membrane protein YlbJ
MW696_RS01215	COG3480	Lon protease (S16) C-terminal proteolytic domain
MW696_RS01220	COG1323	Belongs to the UPF0348 family
MW696_RS01225	COG1399	metal-binding, possibly nucleic acid-binding protein
MW696_RS01230	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MW696_RS01240	COG0454	-acetyltransferase
MW696_RS01245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MW696_RS01250	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MW696_RS01255	COG2001	Belongs to the MraZ family
MW696_RS01260	COG0275	rRNA processing
MW696_RS01265	COG4839	cell division protein FtsL
MW696_RS01270	COG0768	penicillin binding
MW696_RS01275	COG0768	penicillin binding
MW696_RS01280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MW696_RS01285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MW696_RS01290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MW696_RS01295	COG0772	Belongs to the SEDS family
MW696_RS01300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_RS01305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MW696_RS01310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MW696_RS01315	COG3879	Bacterial protein of unknown function (DUF881)
MW696_RS01320	COG3879	Bacterial protein of unknown function (DUF881)
MW696_RS01325	COG3856	small basic protein
MW696_RS01330	COG0849	cell division
MW696_RS01335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MW696_RS01345	COG1404	Belongs to the peptidase S8 family
MW696_RS01345	COG4412	M6 family metalloprotease domain protein
MW696_RS01355	COG1191	sigma factor activity
MW696_RS01360	COG1191	sigma factor activity
MW696_RS01365	COG1119	ATPase activity
MW696_RS01370	COG0500	methyltransferase
MW696_RS01375	COG1873	PFAM PRC-barrel domain
MW696_RS01380	COG1496	oxidoreductase activity
MW696_RS01385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MW696_RS01390	COG1799	cell septum assembly
MW696_RS01395	COG0762	integral membrane protein
MW696_RS01400	COG2302	S4 RNA-binding domain
MW696_RS01405	COG3599	regulation of cell shape
MW696_RS01410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MW696_RS01415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MW696_RS01420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MW696_RS01425	COG0564	pseudouridine synthase activity
MW696_RS01430	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MW696_RS01435	COG2233	PERMEase
MW696_RS01440	COG0540	Belongs to the ATCase OTCase family
MW696_RS01445	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MW696_RS01450	COG0505	Belongs to the CarA family
MW696_RS01455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MW696_RS01460	COG0543	2 iron, 2 sulfur cluster binding
MW696_RS01465	COG0167	dihydroorotate dehydrogenase activity
MW696_RS01470	COG0284	orotidine-5'-phosphate decarboxylase activity
MW696_RS01475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MW696_RS01490	COG0175	sulfate reduction
MW696_RS01495	COG0306	phosphate transporter
MW696_RS01500	COG2046	Belongs to the sulfate adenylyltransferase family
MW696_RS01505	COG0529	Catalyzes the synthesis of activated sulfate
MW696_RS01510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MW696_RS01515	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
MW696_RS01520	COG1648	precorrin-2 dehydrogenase activity
MW696_RS01530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MW696_RS01535	COG1561	YicC-like family, N-terminal region
MW696_RS01540	COG2052	Domain of unknown function (DUF370)
MW696_RS01545	COG0194	GDP metabolic process
MW696_RS01550	COG1758	RNA polymerase activity
MW696_RS01555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MW696_RS01560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MW696_RS01565	COG0242	peptide deformylase activity
MW696_RS01570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MW696_RS01575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MW696_RS01575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MW696_RS01580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MW696_RS01585	COG0631	protein serine/threonine phosphatase activity
MW696_RS01590	COG0515	serine threonine protein kinase
MW696_RS01590	COG2815	serine threonine protein kinase
MW696_RS01595	COG1162	GTPase activity
MW696_RS01600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MW696_RS01605	COG1564	THIamine pyrophosphokinase
MW696_RS01615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MW696_RS01620	COG1302	Protein conserved in bacteria
MW696_RS01625	COG1461	Dihydroxyacetone kinase
MW696_RS01630	COG1760	l-serine dehydratase
MW696_RS01635	COG1760	l-serine dehydratase
MW696_RS01640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MW696_RS01645	COG1349	DNA-binding transcription factor activity
MW696_RS01650	COG0416	fatty acid biosynthetic process
MW696_RS01655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MW696_RS01660	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS01665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MW696_RS01670	COG0571	ribonuclease III activity
MW696_RS01675	COG1196	nuclear chromosome segregation
MW696_RS01680	COG0552	protein localization to endoplasmic reticulum
MW696_RS01685	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MW696_RS01690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MW696_RS01695	COG0228	four-way junction DNA binding
MW696_RS01700	COG1837	Belongs to the UPF0109 family
MW696_RS01710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MW696_RS01715	COG0336	Belongs to the RNA methyltransferase TrmD family
MW696_RS01720	COG0335	large ribosomal subunit rRNA binding
MW696_RS01725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MW696_RS01730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MW696_RS01740	COG2257	FlhB HrpN YscU SpaS Family
MW696_RS01745	COG0045	succinate-CoA ligase (ADP-forming) activity
MW696_RS01750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MW696_RS01755	COG0758	DNA mediated transformation
MW696_RS01760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MW696_RS01765	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MW696_RS01770	COG4974	Belongs to the 'phage' integrase family
MW696_RS01775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MW696_RS01780	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MW696_RS01785	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MW696_RS01790	COG1815	bacterial-type flagellum-dependent cell motility
MW696_RS01795	COG1558	bacterial-type flagellum-dependent cell motility
MW696_RS01800	COG1677	Flagellar hook-basal body complex protein FliE
MW696_RS01805	COG1766	The M ring may be actively involved in energy transduction
MW696_RS01810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MW696_RS01815	COG1317	bacterial-type flagellum organization
MW696_RS01820	COG1157	protein secretion by the type III secretion system
MW696_RS01825	COG2882	bacterial-type flagellum organization
MW696_RS01835	COG3144	bacterial-type flagellum assembly
MW696_RS01840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MW696_RS01845	COG4786	Flagellar basal body rod
MW696_RS01850	COG1582	Flagellar protein (FlbD)
MW696_RS01855	COG1580	Controls the rotational direction of flagella during chemotaxis
MW696_RS01860	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MW696_RS01865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MW696_RS01865	COG1776	CheC inhibitor of MCP methylation
MW696_RS01870	COG2201	protein-glutamate methylesterase activity
MW696_RS01875	COG3190	flagellar
MW696_RS01880	COG1338	Plays a role in the flagellum-specific transport system
MW696_RS01885	COG1987	bacterial-type flagellum assembly
MW696_RS01890	COG1684	flagellar biosynthetic protein fliR
MW696_RS01895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MW696_RS01900	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MW696_RS01905	COG1419	protein localization to endoplasmic reticulum
MW696_RS01910	COG0455	bacterial-type flagellum organization
MW696_RS01915	COG2201	protein-glutamate methylesterase activity
MW696_RS01920	COG0643	Histidine kinase
MW696_RS01920	COG2198	Histidine kinase
MW696_RS01925	COG0835	chemotaxis
MW696_RS01930	COG1776	CheC inhibitor of MCP methylation
MW696_RS01935	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MW696_RS01940	COG1191	sigma factor activity
MW696_RS01950	COG0052	Belongs to the universal ribosomal protein uS2 family
MW696_RS01955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MW696_RS01960	COG0528	UMP kinase activity
MW696_RS01965	COG0233	cytoplasmic translational termination
MW696_RS01970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MW696_RS01975	COG4589	Belongs to the CDS family
MW696_RS01980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MW696_RS01985	COG0750	zinc metalloprotease
MW696_RS01990	COG0442	prolyl-tRNA aminoacylation
MW696_RS01995	COG2176	DNA-directed DNA polymerase activity
MW696_RS02005	COG0457	Tetratricopeptide repeat
MW696_RS02010	COG0779	Required for maturation of 30S ribosomal subunits
MW696_RS02015	COG0195	Participates in both transcription termination and antitermination
MW696_RS02020	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MW696_RS02025	COG1358	cellular component organization or biogenesis
MW696_RS02030	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MW696_RS02035	COG1550	Protein conserved in bacteria
MW696_RS02040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MW696_RS02045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MW696_RS02050	COG0196	riboflavin kinase activity
MW696_RS02055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MW696_RS02060	COG1185	polyribonucleotide nucleotidyltransferase activity
MW696_RS02065	COG0726	polysaccharide deacetylase
MW696_RS02070	COG0612	Peptidase, M16
MW696_RS02075	COG1873	PFAM PRC-barrel domain
MW696_RS02080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_RS02085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MW696_RS02090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MW696_RS02095	COG0527	aspartate kinase activity
MW696_RS02105	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MW696_RS02110	COG0740	serine-type endopeptidase activity
MW696_RS02120	COG4980	gas vesicle protein
MW696_RS02120	COG1674	ftsk spoiiie
MW696_RS02125	COG2188	Transcriptional regulator
MW696_RS02130	COG2814	Major facilitator Superfamily
MW696_RS02135	COG0612	Peptidase, M16
MW696_RS02140	COG0612	Peptidase, M16
MW696_RS02145	COG0300	oxidoreductase activity
MW696_RS02160	COG1426	Protein conserved in bacteria
MW696_RS02165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MW696_RS02170	COG1058	Belongs to the CinA family
MW696_RS02170	COG1546	Belongs to the CinA family
MW696_RS02180	COG1418	mRNA catabolic process
MW696_RS02185	COG1692	metallophosphoesterase
MW696_RS02190	COG2359	stage V sporulation protein S
MW696_RS02200	COG1063	alcohol dehydrogenase
MW696_RS02205	COG0156	8-amino-7-oxononanoate synthase activity
MW696_RS02210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MW696_RS02215	COG4550	Control of competence regulator ComK, YlbF/YmcA
MW696_RS02225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MW696_RS02230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MW696_RS02235	COG2273	Hydrolase Family 16
MW696_RS02245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS02290	COG4282	regulation of fungal-type cell wall biogenesis
MW696_RS02315	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MW696_RS02340	COG3866	Pectate lyase
MW696_RS02345	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_RS02350	COG1522	sequence-specific DNA binding
MW696_RS02355	COG1902	pentaerythritol trinitrate reductase activity
MW696_RS02360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MW696_RS02385	COG0402	S-adenosylhomocysteine deaminase activity
MW696_RS02415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MW696_RS02425	COG2323	membrane
MW696_RS02430	COG3619	membrane
MW696_RS02440	COG2814	Major facilitator Superfamily
MW696_RS02445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS02475	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MW696_RS02480	COG0393	Putative heavy-metal-binding
MW696_RS02485	COG0398	Pfam SNARE associated Golgi protein
MW696_RS02490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MW696_RS02495	COG1819	glycosyl
MW696_RS02500	COG0531	amino acid
MW696_RS02505	COG5577	PFAM Coat F domain
MW696_RS02515	COG3858	chitin binding
MW696_RS02515	COG1388	LysM domain
MW696_RS02520	COG1309	transcriptional regulator
MW696_RS02530	COG1764	response to oxidative stress
MW696_RS02535	COG2076	Multidrug Resistance protein
MW696_RS02540	COG2076	Multidrug Resistance protein
MW696_RS02555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MW696_RS02560	COG1923	regulation of RNA biosynthetic process
MW696_RS02570	COG1780	Probably involved in ribonucleotide reductase function
MW696_RS02575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_RS02580	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_RS02585	COG4112	unkown
MW696_RS02590	COG1802	Transcriptional regulator
MW696_RS02595	COG0697	spore germination
MW696_RS02625	COG4282	regulation of fungal-type cell wall biogenesis
MW696_RS02630	COG1073	alpha beta
MW696_RS02640	COG0464	growth
MW696_RS02645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MW696_RS02650	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MW696_RS02655	COG0789	Transcriptional regulator
MW696_RS02660	COG0174	glutamine synthetase
MW696_RS02680	COG3655	Transcriptional regulator
MW696_RS02685	COG5444	nuclease activity
MW696_RS02695	COG0457	Tetratricopeptide repeat
MW696_RS02710	COG2814	Major facilitator Superfamily
MW696_RS02715	COG0457	Tetratricopeptide repeat
MW696_RS02720	COG0457	Tetratricopeptide repeat
MW696_RS02730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MW696_RS02760	COG2814	Major facilitator Superfamily
MW696_RS02765	COG0457	Tetratricopeptide repeat
MW696_RS02770	COG0490	domain, Protein
MW696_RS02775	COG0475	glutathione-regulated potassium exporter activity
MW696_RS02795	COG0756	dUTP diphosphatase activity
MW696_RS02805	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MW696_RS02830	COG1231	oxidoreductase activity
MW696_RS02835	COG1309	transcriptional regulator
MW696_RS02840	COG2076	Multidrug Resistance protein
MW696_RS02845	COG2076	Multidrug Resistance protein
MW696_RS02850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS02925	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_RS02930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MW696_RS02935	COG1388	LysM domain
MW696_RS02940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MW696_RS02945	COG4224	UPF0291 protein
MW696_RS02950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MW696_RS02960	COG3763	UPF0154 protein
MW696_RS02970	COG0785	Cytochrome C biogenesis protein
MW696_RS02975	COG2201	protein-glutamate methylesterase activity
MW696_RS02980	COG4846	Membrane protein involved in cytochrome C biogenesis
MW696_RS02990	COG0071	Belongs to the small heat shock protein (HSP20) family
MW696_RS03005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MW696_RS03010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS03030	COG0824	Thioesterase
MW696_RS03040	COG4841	protein insertion into membrane
MW696_RS03045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MW696_RS03050	COG1832	CoA-binding protein
MW696_RS03055	COG0187	DNA topoisomerase II activity
MW696_RS03060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MW696_RS03065	COG1609	Transcriptional regulator
MW696_RS03080	COG2160	L-arabinose isomerase activity
MW696_RS03110	COG2181	nitrate reductase activity
MW696_RS03115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MW696_RS03120	COG1140	nitrate reductase beta subunit
MW696_RS03125	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MW696_RS03140	COG0535	radical SAM domain protein
MW696_RS03145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MW696_RS03155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MW696_RS03160	COG2223	nitrite transmembrane transporter activity
MW696_RS03180	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MW696_RS03190	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MW696_RS03205	COG0574	Belongs to the PEP-utilizing enzyme family
MW696_RS03205	COG3848	Pyruvate phosphate dikinase
MW696_RS03215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MW696_RS03220	COG0798	PFAM Bile acid sodium symporter
MW696_RS03225	COG0640	Transcriptional regulator
MW696_RS03230	COG0693	protein deglycase activity
MW696_RS03270	COG1024	Enoyl-CoA hydratase
MW696_RS03275	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS03280	COG2084	Dehydrogenase
MW696_RS03285	COG1960	acyl-CoA dehydrogenase activity
MW696_RS03290	COG0789	Transcriptional regulator
MW696_RS03300	COG1064	alcohol dehydrogenase
MW696_RS03305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MW696_RS03310	COG2814	Major facilitator Superfamily
MW696_RS03315	COG1388	LysM domain
MW696_RS03320	COG2205	protein histidine kinase activity
MW696_RS03345	COG1595	DNA-templated transcription, initiation
MW696_RS03350	COG1482	cell wall glycoprotein biosynthetic process
MW696_RS03355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_RS03355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_RS03355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS03360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS03360	COG3711	transcriptional antiterminator
MW696_RS03365	COG0785	Cytochrome C biogenesis protein
MW696_RS03370	COG2814	Major facilitator Superfamily
MW696_RS03400	COG1725	Transcriptional regulator
MW696_RS03415	COG1309	transcriptional regulator
MW696_RS03445	COG2404	hydrolase activity, acting on ester bonds
MW696_RS03450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MW696_RS03455	COG1882	Formate acetyltransferase
MW696_RS03470	COG2027	D-alanyl-D-alanine carboxypeptidase
MW696_RS03475	COG1252	NADH dehydrogenase
MW696_RS03485	COG0166	Belongs to the GPI family
MW696_RS03495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MW696_RS03500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MW696_RS03505	COG1024	Enoyl-CoA hydratase
MW696_RS03510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MW696_RS03515	COG0511	ligase activity, forming carbon-carbon bonds
MW696_RS03520	COG0439	Biotin carboxylase
MW696_RS03525	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_RS03530	COG1960	acyl-CoA dehydrogenase activity
MW696_RS03535	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_RS03540	COG1733	regulation of RNA biosynthetic process
MW696_RS03580	COG2323	membrane
MW696_RS03585	COG0175	sulfate reduction
MW696_RS03590	COG1809	phosphosulfolactate synthase activity
MW696_RS03595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_RS03600	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_RS03605	COG2814	Major facilitator Superfamily
MW696_RS03610	COG0463	Glycosyl transferase, family 2
MW696_RS03625	COG0493	'glutamate synthase
MW696_RS03630	COG0069	glutamate synthase activity
MW696_RS03630	COG0070	glutamate synthase
MW696_RS03630	COG0067	glutamate synthase
MW696_RS03635	COG0583	DNA-binding transcription factor activity
MW696_RS03660	COG1132	(ABC) transporter
MW696_RS03665	COG3540	Alkaline phosphatase
MW696_RS03675	COG0300	oxidoreductase activity
MW696_RS03680	COG0477	Major facilitator Superfamily
MW696_RS03685	COG0243	molybdopterin cofactor binding
MW696_RS03690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MW696_RS03695	COG1846	Transcriptional regulator
MW696_RS03700	COG2814	Major facilitator Superfamily
MW696_RS03705	COG0531	amino acid
MW696_RS03715	COG0531	amino acid
MW696_RS03720	COG0531	amino acid
MW696_RS03725	COG0697	spore germination
MW696_RS03730	COG0488	(ABC) transporter
MW696_RS03750	COG0840	transmembrane signaling receptor activity
MW696_RS03755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_RS03760	COG1404	Belongs to the peptidase S8 family
MW696_RS03770	COG1309	transcriptional regulator
MW696_RS03780	COG1309	transcriptional regulator
MW696_RS03785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS03790	COG3708	Transcriptional regulator
MW696_RS03805	COG2378	regulation of single-species biofilm formation
MW696_RS03815	COG0640	Transcriptional regulator
MW696_RS03825	COG0531	amino acid
MW696_RS03830	COG0741	lytic transglycosylase activity
MW696_RS03835	COG1086	Polysaccharide biosynthesis protein
MW696_RS03855	COG2322	membrane
MW696_RS03865	COG1619	proteins homologs of microcin C7 resistance protein MccF
MW696_RS03870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS03875	COG1388	LysM domain
MW696_RS03885	COG3584	3D domain protein
MW696_RS03885	COG1388	LysM domain
MW696_RS03890	COG0514	ATP-dependent DNA helicase (RecQ)
MW696_RS03925	COG4282	regulation of fungal-type cell wall biogenesis
MW696_RS03970	COG5444	nuclease activity
MW696_RS03985	COG0457	Tetratricopeptide repeat
MW696_RS04010	COG0702	epimerase
MW696_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS04030	COG1357	PFAM Pentapeptide repeats (8 copies)
MW696_RS04045	COG1280	lysine exporter protein (LysE YggA)
MW696_RS04050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MW696_RS04085	COG5634	Uncharacterized conserved protein (DUF2278)
MW696_RS04105	COG2318	DinB family
MW696_RS04110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MW696_RS04115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MW696_RS04120	COG2140	Oxalate decarboxylase
MW696_RS04140	COG0288	reversible hydration of carbon dioxide
MW696_RS04145	COG3002	Belongs to the UPF0753 family
MW696_RS04150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MW696_RS04155	COG5609	conserved protein (DUF2294)
MW696_RS04175	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS04195	COG0667	Aldo Keto reductase
MW696_RS04200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MW696_RS04205	COG1846	Transcriptional regulator
MW696_RS04210	COG1657	PFAM Prenyltransferase squalene oxidase
MW696_RS04215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MW696_RS04220	COG0733	neurotransmitter:sodium symporter activity
MW696_RS04225	COG0385	Bile acid
MW696_RS04230	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_RS04235	COG0567	Dehydrogenase, E1 component
MW696_RS04240	COG4548	von Willebrand factor, type A
MW696_RS04245	COG0714	Associated with various cellular activities
MW696_RS04250	COG2032	superoxide dismutase activity
MW696_RS04255	COG0791	NLP P60 protein
MW696_RS04255	COG1388	LysM domain
MW696_RS04260	COG0534	Mate efflux family protein
MW696_RS04265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MW696_RS04270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MW696_RS04280	COG2962	Rard protein
MW696_RS04290	COG4305	rare lipoprotein A
MW696_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS04305	COG1733	regulation of RNA biosynthetic process
MW696_RS04310	COG0778	Nitroreductase
MW696_RS04315	COG0400	carboxylic ester hydrolase activity
MW696_RS04320	COG0346	lactoylglutathione lyase activity
MW696_RS04330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_RS04335	COG3409	Peptidoglycan-binding domain 1 protein
MW696_RS04335	COG0793	Belongs to the peptidase S41A family
MW696_RS04340	COG2226	methyltransferase
MW696_RS04350	COG1876	peptidase activity
MW696_RS04355	COG0813	purine-nucleoside phosphorylase activity
MW696_RS04360	COG0701	Predicted permease
MW696_RS04380	COG0671	phosphoesterase, PA-phosphatase related
MW696_RS04400	COG4479	Belongs to the UPF0346 family
MW696_RS04410	COG1509	lysine 2,3-aminomutase activity
MW696_RS04415	COG0456	acetyltransferase
MW696_RS04420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MW696_RS04425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MW696_RS04430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MW696_RS04435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MW696_RS04445	COG0456	acetyltransferase
MW696_RS04450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MW696_RS04455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MW696_RS04460	COG1846	Transcriptional regulator
MW696_RS04470	COG0534	Mate efflux family protein
MW696_RS04485	COG4698	Protein conserved in bacteria
MW696_RS04490	COG2755	lipolytic protein G-D-S-L family
MW696_RS04495	COG1999	signal sequence binding
MW696_RS04510	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MW696_RS04515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MW696_RS04520	COG1272	protein, Hemolysin III
MW696_RS04525	COG0204	Acyl-transferase
MW696_RS04530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MW696_RS04535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MW696_RS04550	COG2521	methyltransferase
MW696_RS04550	COG2136	Putative SAM-dependent methyltransferase
MW696_RS04560	COG0129	dihydroxy-acid dehydratase activity
MW696_RS04565	COG1413	lyase activity
MW696_RS04570	COG1418	mRNA catabolic process
MW696_RS04575	COG0386	Belongs to the glutathione peroxidase family
MW696_RS04580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MW696_RS04585	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MW696_RS04590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_RS04600	COG1278	Cold shock
MW696_RS04620	COG0328	RNA-DNA hybrid ribonuclease activity
MW696_RS04625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MW696_RS04630	COG0328	RNA-DNA hybrid ribonuclease activity
MW696_RS04640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_RS04655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MW696_RS04665	COG1755	Isoprenylcysteine carboxyl methyltransferase
MW696_RS04670	COG3424	synthase
MW696_RS04680	COG2233	PERMEase
MW696_RS04685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MW696_RS04690	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MW696_RS04695	COG1199	ATP-dependent helicase activity
MW696_RS04710	COG0116	Belongs to the methyltransferase superfamily
MW696_RS04720	COG3599	regulation of cell shape
MW696_RS04725	COG4474	Belongs to the UPF0398 family
MW696_RS04735	COG3359	exonuclease
MW696_RS04740	COG1111	helicase
MW696_RS04740	COG1205	dead DEAH box helicase
MW696_RS04745	COG2190	(PTS) system
MW696_RS04750	COG0071	Belongs to the small heat shock protein (HSP20) family
MW696_RS04785	COG3331	DNA recombination
MW696_RS04790	COG4499	WXG100 protein secretion system (Wss), protein YukC
MW696_RS04790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_RS04800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MW696_RS04805	COG3935	DnaD domain protein
MW696_RS04810	COG0017	Asparaginyl-tRNA synthetase
MW696_RS04815	COG0436	Aminotransferase
MW696_RS04820	COG5353	protein conserved in bacteria
MW696_RS04830	COG1199	ATP-dependent helicase activity
MW696_RS04830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MW696_RS04835	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MW696_RS04840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MW696_RS04845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MW696_RS04855	COG0617	tRNA 3'-terminal CCA addition
MW696_RS04860	COG0438	transferase activity, transferring glycosyl groups
MW696_RS04865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MW696_RS04870	COG1803	Methylglyoxal synthase
MW696_RS04875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MW696_RS04880	COG1694	Mazg nucleotide pyrophosphohydrolase
MW696_RS04885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_RS04895	COG4347	Protein of unknown function (DUF1405)
MW696_RS04900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MW696_RS04900	COG2010	Cytochrome c
MW696_RS04905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MW696_RS04910	COG0723	plastoquinol--plastocyanin reductase activity
MW696_RS04920	COG5582	Belongs to the UPF0302 family
MW696_RS04925	COG0457	Tetratricopeptide repeat
MW696_RS04930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MW696_RS04935	COG0287	Prephenate dehydrogenase
MW696_RS04940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MW696_RS04945	COG0159	tryptophan synthase activity
MW696_RS04950	COG0133	tryptophan synthase activity
MW696_RS04955	COG0135	phosphoribosylanthranilate isomerase activity
MW696_RS04960	COG0134	indole-3-glycerol-phosphate synthase activity
MW696_RS04965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MW696_RS04970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MW696_RS04975	COG4401	Chorismate mutase type I
MW696_RS04980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MW696_RS04985	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MW696_RS04990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MW696_RS04995	COG0105	UTP biosynthetic process
MW696_RS05000	COG0142	geranyltranstransferase activity
MW696_RS05005	COG2226	methyltransferase
MW696_RS05010	COG0142	geranyltranstransferase activity
MW696_RS05025	COG0776	regulation of translation
MW696_RS05030	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MW696_RS05045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MW696_RS05050	COG1160	GTP binding
MW696_RS05075	COG1304	FMN binding
MW696_RS05080	COG0539	negative regulation of cytoplasmic translation
MW696_RS05085	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MW696_RS05095	COG2959	enzyme of heme biosynthesis
MW696_RS05100	COG3409	Peptidoglycan-binding domain 1 protein
MW696_RS05100	COG3773	Cell wall hydrolase
MW696_RS05105	COG2339	peptidase activity
MW696_RS05115	COG0492	ferredoxin-NADP+ reductase activity
MW696_RS05120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MW696_RS05125	COG4862	establishment of competence for transformation
MW696_RS05130	COG1408	metallophosphoesterase
MW696_RS05140	COG1388	LysM domain
MW696_RS05145	COG1266	CAAX protease self-immunity
MW696_RS05150	COG0514	ATP-dependent DNA helicase (RecQ)
MW696_RS05155	COG4955	Helix-turn-helix domain
MW696_RS05160	COG1141	Ferredoxin
MW696_RS05165	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MW696_RS05170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MW696_RS05175	COG0739	heme binding
MW696_RS05185	COG1595	DNA-templated transcription, initiation
MW696_RS05205	COG5002	protein histidine kinase activity
MW696_RS05210	COG0745	RESPONSE REGULATOR receiver
MW696_RS05215	COG5002	protein histidine kinase activity
MW696_RS05220	COG0745	RESPONSE REGULATOR receiver
MW696_RS05225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MW696_RS05230	COG1333	cytochrome c biogenesis protein
MW696_RS05235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS05240	COG1187	pseudouridine synthase activity
MW696_RS05245	COG0700	Nucleoside recognition
MW696_RS05250	COG2715	membrane protein required for spore maturation
MW696_RS05255	COG1686	Belongs to the peptidase S11 family
MW696_RS05265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MW696_RS05270	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MW696_RS05275	COG1547	Domain of unknown function (DUF309)
MW696_RS05280	COG0456	acetyltransferase
MW696_RS05285	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MW696_RS05290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MW696_RS05290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MW696_RS05295	COG0307	riboflavin synthase, alpha
MW696_RS05300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MW696_RS05300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MW696_RS05320	COG0457	Tetratricopeptide repeat
MW696_RS05325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MW696_RS05330	COG4086	secreted protein
MW696_RS05335	COG4195	phage-related replication protein
MW696_RS05345	COG0019	diaminopimelate decarboxylase activity
MW696_RS05355	COG0697	spore germination
MW696_RS05370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_RS05405	COG1686	Belongs to the peptidase S11 family
MW696_RS05410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MW696_RS05415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MW696_RS05420	COG4974	Belongs to the 'phage' integrase family
MW696_RS05430	COG0735	belongs to the Fur family
MW696_RS05435	COG1300	Membrane
MW696_RS05440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_RS05455	COG4122	O-methyltransferase activity
MW696_RS05465	COG1379	DNA repair
MW696_RS05470	COG0494	nUDIX hydrolase
MW696_RS05480	COG1309	transcriptional regulator
MW696_RS05490	COG0667	Aldo Keto reductase
MW696_RS05495	COG0477	Major facilitator Superfamily
MW696_RS05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS05505	COG3420	alginic acid biosynthetic process
MW696_RS05520	COG1073	alpha beta
MW696_RS05530	COG4918	Iron-sulphur cluster biosynthesis
MW696_RS05540	COG0456	acetyltransferase
MW696_RS05540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MW696_RS05550	COG0456	acetyltransferase
MW696_RS05560	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MW696_RS05580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MW696_RS05595	COG2211	Major facilitator Superfamily
MW696_RS05600	COG0346	lactoylglutathione lyase activity
MW696_RS05605	COG1072	(Pantothenic acid kinase))
MW696_RS05615	COG1131	(ABC) transporter
MW696_RS05650	COG4195	phage-related replication protein
MW696_RS05655	COG0300	oxidoreductase activity
MW696_RS05660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS05665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MW696_RS05670	COG4187	Peptidase family M20/M25/M40
MW696_RS05675	COG1902	pentaerythritol trinitrate reductase activity
MW696_RS05680	COG0596	Alpha beta hydrolase
MW696_RS05685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MW696_RS05690	COG1234	tRNA 3'-trailer cleavage
MW696_RS05695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MW696_RS05700	COG2188	Transcriptional regulator
MW696_RS05705	COG2723	6-phospho-beta-galactosidase activity
MW696_RS05710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_RS05715	COG1447	Phosphotransferase system cellobiose-specific component IIA
MW696_RS05720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_RS05725	COG1785	Belongs to the alkaline phosphatase family
MW696_RS05730	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS05735	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MW696_RS05740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MW696_RS05750	COG0706	membrane insertase activity
MW696_RS05760	COG2195	Cleaves the N-terminal amino acid of tripeptides
MW696_RS05765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MW696_RS05775	COG4129	membrane
MW696_RS05780	COG1126	abc transporter atp-binding protein
MW696_RS05785	COG0765	amino acid transport
MW696_RS05790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_RS05800	COG1597	lipid kinase activity
MW696_RS05805	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_RS05810	COG0022	dehydrogenase e1 component
MW696_RS05815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MW696_RS05820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MW696_RS05825	COG3426	butyrate kinase activity
MW696_RS05835	COG0280	phosphate acetyltransferase
MW696_RS05840	COG3290	protein histidine kinase activity
MW696_RS05840	COG3829	transcription factor binding
MW696_RS05850	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_RS05855	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MW696_RS05870	COG0745	RESPONSE REGULATOR receiver
MW696_RS05875	COG0750	zinc metalloprotease
MW696_RS05880	COG0497	DNA recombination
MW696_RS05885	COG1438	arginine binding
MW696_RS05890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MW696_RS05895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MW696_RS05900	COG0142	geranyltranstransferase activity
MW696_RS05905	COG1722	exodeoxyribonuclease VII activity
MW696_RS05910	COG1570	exodeoxyribonuclease VII activity
MW696_RS05915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MW696_RS05920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MW696_RS05925	COG1302	Protein conserved in bacteria
MW696_RS05930	COG0439	Biotin carboxylase
MW696_RS05935	COG0511	ligase activity, forming carbon-carbon bonds
MW696_RS05975	COG3854	ATPases associated with a variety of cellular activities
MW696_RS05990	COG0006	proline dipeptidase activity
MW696_RS05995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MW696_RS06005	COG3872	metal-dependent enzyme
MW696_RS06015	COG1752	Esterase of the alpha-beta hydrolase superfamily
MW696_RS06020	COG1321	iron dependent repressor
MW696_RS06030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_RS06035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MW696_RS06040	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MW696_RS06045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MW696_RS06050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MW696_RS06075	COG0681	Belongs to the peptidase S26 family
MW696_RS06100	COG4940	Competence protein ComGF
MW696_RS06110	COG4970	Tfp pilus assembly protein FimT
MW696_RS06115	COG4537	Required for transformation and DNA binding
MW696_RS06120	COG1459	type II secretion system
MW696_RS06125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MW696_RS06130	COG1366	Belongs to the anti-sigma-factor antagonist family
MW696_RS06140	COG1393	Belongs to the ArsC family
MW696_RS06150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS06160	COG0011	TIGRFAM Protein of
MW696_RS06170	COG2866	Carboxypeptidase
MW696_RS06175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS06185	COG2116	formate transmembrane transporter activity
MW696_RS06200	COG1368	sulfuric ester hydrolase activity
MW696_RS06205	COG1940	carbohydrate kinase activity
MW696_RS06210	COG4483	Protein conserved in bacteria
MW696_RS06215	COG0697	spore germination
MW696_RS06220	COG0705	Rhomboid family
MW696_RS06220	COG0457	Tetratricopeptide repeat
MW696_RS06230	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MW696_RS06245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MW696_RS06250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MW696_RS06255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MW696_RS06260	COG0581	inorganic phosphate transmembrane transporter activity
MW696_RS06265	COG0573	inorganic phosphate transmembrane transporter activity
MW696_RS06270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MW696_RS06275	COG0768	penicillin binding
MW696_RS06280	COG0477	Major facilitator Superfamily
MW696_RS06285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MW696_RS06290	COG2839	Protein conserved in bacteria
MW696_RS06295	COG5521	maltodextrose utilization protein MalA
MW696_RS06300	COG1388	LysM domain
MW696_RS06305	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MW696_RS06310	COG4709	membrane
MW696_RS06315	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
MW696_RS06320	COG0735	belongs to the Fur family
MW696_RS06325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MW696_RS06330	COG1121	(ABC) transporter
MW696_RS06335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_RS06345	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MW696_RS06350	COG0513	Belongs to the DEAD box helicase family
MW696_RS06360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MW696_RS06365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MW696_RS06370	COG2384	SAM-dependent methyltransferase
MW696_RS06400	COG5444	nuclease activity
MW696_RS06410	COG2010	Cytochrome c
MW696_RS06415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MW696_RS06420	COG0358	DNA primase activity
MW696_RS06425	COG1671	Belongs to the UPF0178 family
MW696_RS06430	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MW696_RS06435	COG0517	IMP dehydrogenase activity
MW696_RS06440	COG0751	glycine-tRNA ligase activity
MW696_RS06445	COG0752	glycyl-tRNA synthetase alpha subunit
MW696_RS06450	COG1381	Involved in DNA repair and RecF pathway recombination
MW696_RS06460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MW696_RS06465	COG0295	cytidine deaminase activity
MW696_RS06470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MW696_RS06475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MW696_RS06480	COG1480	7TM receptor with intracellular HD hydrolase
MW696_RS06485	COG1702	phosphate starvation-inducible protein PhoH
MW696_RS06490	COG0561	phosphatase activity
MW696_RS06505	COG4864	UPF0365 protein
MW696_RS06510	COG1030	water channel activity
MW696_RS06515	COG1610	YqeY-like protein
MW696_RS06520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MW696_RS06525	COG1283	sodium-dependent phosphate transmembrane transporter activity
MW696_RS06530	COG1247	-acetyltransferase
MW696_RS06535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MW696_RS06540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MW696_RS06545	COG2264	protein methyltransferase activity
MW696_RS06550	COG0484	heat shock protein binding
MW696_RS06555	COG0443	Heat shock 70 kDa protein
MW696_RS06560	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MW696_RS06565	COG1420	regulation of RNA biosynthetic process
MW696_RS06570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MW696_RS06575	COG0481	GTPase activity
MW696_RS06585	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_RS06590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MW696_RS06595	COG0268	Binds directly to 16S ribosomal RNA
MW696_RS06600	COG1466	dna polymerase III delta subunit
MW696_RS06610	COG0658	competence protein
MW696_RS06610	COG2333	competence protein COMEC
MW696_RS06615	COG2131	deaminase
MW696_RS06620	COG1555	photosystem II stabilization
MW696_RS06620	COG1596	polysaccharide export
MW696_RS06625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MW696_RS06630	COG2226	methyltransferase
MW696_RS06635	COG0799	negative regulation of ribosome biogenesis
MW696_RS06640	COG1713	HD superfamily hydrolase involved in NAD metabolism
MW696_RS06645	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MW696_RS06650	COG1534	Rna-binding protein
MW696_RS06655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MW696_RS06660	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MW696_RS06665	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MW696_RS06680	COG2755	lipolytic protein G-D-S-L family
MW696_RS06690	COG5609	conserved protein (DUF2294)
MW696_RS06695	COG3383	formate dehydrogenase (NAD+) activity
MW696_RS06700	COG2427	Protein of unknown function (DUF1641)
MW696_RS06720	COG0457	Tetratricopeptide repeat
MW696_RS06725	COG5444	nuclease activity
MW696_RS06755	COG1793	dna ligase
MW696_RS06830	COG0551	DNA topoisomerase type I activity
MW696_RS06830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MW696_RS06885	COG0739	heme binding
MW696_RS07005	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MW696_RS07095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MW696_RS07110	COG1309	transcriptional regulator
MW696_RS07115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MW696_RS07125	COG0730	response to heat
MW696_RS07130	COG0425	Belongs to the sulfur carrier protein TusA family
MW696_RS07135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS07135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_RS07140	COG2210	Belongs to the sulfur carrier protein TusA family
MW696_RS07145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_RS07145	COG0425	Belongs to the sulfur carrier protein TusA family
MW696_RS07155	COG2210	Belongs to the sulfur carrier protein TusA family
MW696_RS07160	COG1937	Protein conserved in bacteria
MW696_RS07165	COG1054	Belongs to the UPF0176 family
MW696_RS07175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MW696_RS07215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MW696_RS07230	COG0494	nUDIX hydrolase
MW696_RS07235	COG1733	regulation of RNA biosynthetic process
MW696_RS07240	COG0477	Major facilitator Superfamily
MW696_RS07245	COG2723	6-phospho-beta-galactosidase activity
MW696_RS07250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS07250	COG1263	PTS System
MW696_RS07250	COG2190	(PTS) system
MW696_RS07255	COG3711	transcriptional antiterminator
MW696_RS07260	COG1522	sequence-specific DNA binding
MW696_RS07265	COG1335	isochorismatase
MW696_RS07285	COG0697	spore germination
MW696_RS07295	COG0583	DNA-binding transcription factor activity
MW696_RS07300	COG2070	2-Nitropropane dioxygenase
MW696_RS07310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MW696_RS07315	COG0604	alcohol dehydrogenase
MW696_RS07320	COG2188	Transcriptional regulator
MW696_RS07340	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS07345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MW696_RS07350	COG3959	Transketolase, thiamine diphosphate binding domain
MW696_RS07370	COG0789	Transcriptional regulator
MW696_RS07370	COG4978	Transcriptional regulator
MW696_RS07405	COG0071	Belongs to the small heat shock protein (HSP20) family
MW696_RS07410	COG2409	Drug exporters of the RND superfamily
MW696_RS07415	COG2197	response regulator
MW696_RS07420	COG4585	Histidine kinase
MW696_RS07435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MW696_RS07440	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
MW696_RS07445	COG1733	regulation of RNA biosynthetic process
MW696_RS07455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS07465	COG2197	response regulator
MW696_RS07470	COG4585	Histidine kinase
MW696_RS07480	COG0730	response to heat
MW696_RS07485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_RS07485	COG0425	Belongs to the sulfur carrier protein TusA family
MW696_RS07490	COG2210	Belongs to the sulfur carrier protein TusA family
MW696_RS07495	COG1937	Protein conserved in bacteria
MW696_RS07505	COG3239	Fatty acid desaturase
MW696_RS07510	COG4585	Histidine kinase
MW696_RS07515	COG2197	response regulator
MW696_RS07520	COG0492	ferredoxin-NADP+ reductase activity
MW696_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS07535	COG1942	4-Oxalocrotonate Tautomerase
MW696_RS07550	COG3443	Belongs to the bacterial solute-binding protein 9 family
MW696_RS07560	COG2124	cytochrome p450
MW696_RS07565	COG2368	4-hydroxyphenylacetate
MW696_RS07575	COG0833	amino acid
MW696_RS07580	COG4187	Peptidase family M20/M25/M40
MW696_RS07585	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MW696_RS07600	COG5583	Uncharacterized small protein (DUF2292)
MW696_RS07610	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_RS07620	COG1917	Cupin 2, conserved barrel domain protein
MW696_RS07620	COG4977	sequence-specific DNA binding
MW696_RS07630	COG1621	beta-fructofuranosidase activity
MW696_RS07635	COG3716	PTS system mannose fructose sorbose family IID component
MW696_RS07640	COG3715	PTS system
MW696_RS07645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS07650	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS07655	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MW696_RS07655	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MW696_RS07670	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MW696_RS07685	COG1113	amino acid transport
MW696_RS07700	COG1525	nuclease
MW696_RS07715	COG2814	Major facilitator Superfamily
MW696_RS07725	COG2350	Protein conserved in bacteria
MW696_RS07735	COG2169	Transcriptional regulator
MW696_RS07740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MW696_RS07745	COG0656	L-ascorbic acid biosynthetic process
MW696_RS07750	COG2814	Major facilitator Superfamily
MW696_RS07755	COG1733	regulation of RNA biosynthetic process
MW696_RS07760	COG1587	Uroporphyrinogen-III synthase
MW696_RS07770	COG0583	DNA-binding transcription factor activity
MW696_RS07775	COG2814	Major facilitator Superfamily
MW696_RS07785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MW696_RS07785	COG2124	cytochrome p450
MW696_RS07790	COG1309	transcriptional regulator
MW696_RS07800	COG1404	Belongs to the peptidase S8 family
MW696_RS07805	COG2226	methyltransferase
MW696_RS07830	COG0626	cystathionine gamma-synthase activity
MW696_RS07835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MW696_RS07840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MW696_RS07845	COG2226	methyltransferase
MW696_RS07860	COG0768	penicillin binding
MW696_RS07865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MW696_RS07870	COG0572	uridine kinase
MW696_RS07875	COG0826	peptidase U32
MW696_RS07880	COG0826	peptidase U32
MW696_RS07885	COG4122	O-methyltransferase activity
MW696_RS07890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MW696_RS07895	COG3906	Belongs to the UPF0473 family
MW696_RS07900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MW696_RS07905	COG4472	Bacterial protein of unknown function (DUF965)
MW696_RS07910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MW696_RS07915	COG0628	permease
MW696_RS07920	COG1126	abc transporter atp-binding protein
MW696_RS07925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_RS07930	COG0765	amino acid transport
MW696_RS07935	COG0765	amino acid transport
MW696_RS07950	COG3881	PFAM PRC-barrel domain
MW696_RS07955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MW696_RS07960	COG0457	Tetratricopeptide repeat
MW696_RS07965	COG0482	sulfurtransferase activity
MW696_RS07970	COG1104	cysteine desulfurase activity
MW696_RS07975	COG1959	2 iron, 2 sulfur cluster binding
MW696_RS07980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MW696_RS07990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MW696_RS08000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MW696_RS08005	COG0124	histidyl-tRNA synthetase
MW696_RS08015	COG3103	Sh3 type 3 domain protein
MW696_RS08015	COG4991	sh3 domain protein
MW696_RS08015	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_RS08020	COG1490	D-aminoacyl-tRNA deacylase activity
MW696_RS08025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MW696_RS08030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MW696_RS08035	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MW696_RS08035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MW696_RS08040	COG5416	Lipopolysaccharide assembly protein A domain
MW696_RS08045	COG0490	domain, Protein
MW696_RS08050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MW696_RS08050	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MW696_RS08060	COG2244	polysaccharide biosynthetic process
MW696_RS08065	COG2323	membrane
MW696_RS08075	COG1862	Preprotein translocase
MW696_RS08080	COG0343	queuine tRNA-ribosyltransferase activity
MW696_RS08085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MW696_RS08095	COG2255	four-way junction helicase activity
MW696_RS08100	COG0632	four-way junction helicase activity
MW696_RS08110	COG2112	serine threonine protein kinase
MW696_RS08120	COG2318	DinB family
MW696_RS08125	COG4195	phage-related replication protein
MW696_RS08140	COG0217	transcriptional regulatory protein
MW696_RS08150	COG1388	LysM domain
MW696_RS08155	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MW696_RS08160	COG0157	Belongs to the NadC ModD family
MW696_RS08165	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MW696_RS08175	COG1827	regulation of RNA biosynthetic process
MW696_RS08180	COG0077	Prephenate dehydratase
MW696_RS08185	COG4492	Belongs to the UPF0735 family
MW696_RS08190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MW696_RS08195	COG3290	protein histidine kinase activity
MW696_RS08200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MW696_RS08205	COG2868	ribosomal protein
MW696_RS08210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MW696_RS08215	COG1994	Peptidase M50
MW696_RS08220	COG0739	heme binding
MW696_RS08225	COG3832	glyoxalase III activity
MW696_RS08230	COG0640	Transcriptional regulator
MW696_RS08235	COG2894	cell division
MW696_RS08240	COG0850	regulation of cytokinetic process
MW696_RS08245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MW696_RS08255	COG1077	Cell shape determining protein MreB Mrl
MW696_RS08260	COG2003	Belongs to the UPF0758 family
MW696_RS08265	COG0424	maF-like protein
MW696_RS08275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MW696_RS08280	COG0285	dihydrofolate synthase activity
MW696_RS08285	COG0525	valine-tRNA ligase activity
MW696_RS08295	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MW696_RS08300	COG1388	LysM domain
MW696_RS08305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MW696_RS08310	COG0113	porphobilinogen synthase activity
MW696_RS08315	COG1587	Uroporphyrinogen-III synthase
MW696_RS08320	COG0181	hydroxymethylbilane synthase activity
MW696_RS08325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MW696_RS08330	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MW696_RS08340	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MW696_RS08345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MW696_RS08350	COG0470	DNA polymerase III
MW696_RS08350	COG1067	ATP-dependent peptidase activity
MW696_RS08355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MW696_RS08360	COG0544	peptidyl-prolyl cis-trans isomerase activity
MW696_RS08365	COG0457	Tetratricopeptide repeat
MW696_RS08365	COG1477	protein flavinylation
MW696_RS08370	COG0066	3-isopropylmalate dehydratase activity
MW696_RS08375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MW696_RS08380	COG0473	3-isopropylmalate dehydrogenase activity
MW696_RS08385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MW696_RS08390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MW696_RS08395	COG0440	acetolactate synthase activity
MW696_RS08400	COG0028	Belongs to the TPP enzyme family
MW696_RS08405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MW696_RS08415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MW696_RS08440	COG5444	nuclease activity
MW696_RS08450	COG0622	Phosphoesterase
MW696_RS08455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MW696_RS08460	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MW696_RS08465	COG5401	PFAM Sporulation and spore germination
MW696_RS08470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MW696_RS08475	COG1846	Transcriptional regulator
MW696_RS08480	COG2197	response regulator
MW696_RS08485	COG4221	oxidoreductase activity
MW696_RS08490	COG0824	Thioesterase
MW696_RS08495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MW696_RS08500	COG1053	succinate dehydrogenase
MW696_RS08505	COG2009	succinate dehydrogenase
MW696_RS08510	COG1719	4-vinyl reductase, 4VR
MW696_RS08520	COG0527	aspartate kinase activity
MW696_RS08525	COG0322	excinuclease ABC activity
MW696_RS08530	COG3118	belongs to the thioredoxin family
MW696_RS08535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MW696_RS08540	COG2086	electron transfer activity
MW696_RS08545	COG1024	Enoyl-CoA hydratase
MW696_RS08550	COG1309	transcriptional regulator
MW696_RS08555	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_RS08560	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_RS08570	COG3766	membrane
MW696_RS08575	COG1193	negative regulation of DNA recombination
MW696_RS08580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MW696_RS08580	COG1796	DNA polymerase
MW696_RS08585	COG1286	toxin biosynthetic process
MW696_RS08590	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MW696_RS08595	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MW696_RS08610	COG0072	phenylalanine-tRNA ligase activity
MW696_RS08610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_RS08615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MW696_RS08620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MW696_RS08630	COG1966	Carbon starvation protein
MW696_RS08635	COG1309	transcriptional regulator
MW696_RS08640	COG3402	PFAM membrane-flanked domain
MW696_RS08645	COG3428	Bacterial PH domain
MW696_RS08660	COG0395	ABC-type sugar transport system, permease component
MW696_RS08665	COG1175	transmembrane transport
MW696_RS08670	COG1653	transport
MW696_RS08675	COG0371	Dehydrogenase
MW696_RS08680	COG0235	Class ii aldolase
MW696_RS08685	COG1069	ribulokinase activity
MW696_RS08690	COG2160	L-arabinose isomerase activity
MW696_RS08700	COG1363	Peptidase, m42
MW696_RS08710	COG3326	Membrane
MW696_RS08715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MW696_RS08725	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MW696_RS08730	COG1346	cytolysis
MW696_RS08735	COG1380	Effector of murein hydrolase LrgA
MW696_RS08740	COG3540	Alkaline phosphatase
MW696_RS08745	COG3279	Response regulator of the LytR AlgR family
MW696_RS08750	COG3275	phosphorelay sensor kinase activity
MW696_RS08755	COG1011	Hydrolase
MW696_RS08770	COG0398	Pfam SNARE associated Golgi protein
MW696_RS08775	COG1484	DNA-dependent DNA replication
MW696_RS08780	COG3611	Membrane attachment protein
MW696_RS08785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MW696_RS08795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MW696_RS08800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MW696_RS08805	COG3866	Pectate lyase
MW696_RS08810	COG0237	dephospho-CoA kinase activity
MW696_RS08815	COG1971	Probably functions as a manganese efflux pump
MW696_RS08820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MW696_RS08825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_RS08825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_RS08830	COG5002	protein histidine kinase activity
MW696_RS08835	COG0745	RESPONSE REGULATOR receiver
MW696_RS08840	COG0039	L-malate dehydrogenase activity
MW696_RS08845	COG0538	isocitrate dehydrogenase activity
MW696_RS08850	COG0372	Belongs to the citrate synthase family
MW696_RS08855	COG2707	UPF0756 membrane protein
MW696_RS08860	COG0628	permease
MW696_RS08865	COG3030	protein affecting phage T7 exclusion by the F plasmid
MW696_RS08875	COG0205	6-phosphofructokinase activity
MW696_RS08880	COG0825	malonyl-CoA metabolic process
MW696_RS08885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MW696_RS08890	COG0281	malic enzyme
MW696_RS08895	COG0587	DNA-directed DNA polymerase activity
MW696_RS08915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MW696_RS08925	COG4109	DRTGG domain
MW696_RS08930	COG1695	Transcriptional regulator
MW696_RS08935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MW696_RS08940	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS08950	COG0165	Argininosuccinate lyase
MW696_RS08955	COG0137	argininosuccinate synthase activity
MW696_RS08960	COG0521	Mo-molybdopterin cofactor biosynthetic process
MW696_RS08965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MW696_RS08970	COG0827	DNA restriction-modification system
MW696_RS08975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MW696_RS08980	COG3874	Sporulation protein YtfJ
MW696_RS08990	COG1714	RDD family
MW696_RS08995	COG0616	signal peptide processing
MW696_RS09000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MW696_RS09010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MW696_RS09020	COG0301	tRNA thio-modification
MW696_RS09025	COG1104	cysteine desulfurase activity
MW696_RS09030	COG1114	Component of the transport system for branched-chain amino acids
MW696_RS09035	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MW696_RS09040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MW696_RS09045	COG1309	transcriptional regulator
MW696_RS09050	COG1956	GAF domain-containing protein
MW696_RS09055	COG2203	Gaf domain
MW696_RS09055	COG2199	diguanylate cyclase activity
MW696_RS09060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MW696_RS09080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MW696_RS09085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MW696_RS09090	COG0454	-acetyltransferase
MW696_RS09095	COG0517	IMP dehydrogenase activity
MW696_RS09100	COG0123	including yeast histone deacetylase and acetoin utilization protein
MW696_RS09105	COG1360	Flagellar Motor Protein
MW696_RS09110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MW696_RS09115	COG1609	Transcriptional regulator
MW696_RS09120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MW696_RS09120	COG1605	Chorismate mutase
MW696_RS09130	COG3118	belongs to the thioredoxin family
MW696_RS09135	COG4980	gas vesicle protein
MW696_RS09140	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MW696_RS09145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MW696_RS09150	COG1674	ftsk spoiiie
MW696_RS09155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_RS09160	COG4848	Belongs to the UPF0354 family
MW696_RS09165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS09175	COG1363	Peptidase, m42
MW696_RS09180	COG5584	Small secreted protein
MW696_RS09185	COG0281	malic enzyme
MW696_RS09190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS09195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MW696_RS09205	COG0510	thiamine kinase activity
MW696_RS09210	COG1597	lipid kinase activity
MW696_RS09220	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MW696_RS09225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MW696_RS09235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MW696_RS09240	COG2252	PERMEase
MW696_RS09245	COG1349	DNA-binding transcription factor activity
MW696_RS09250	COG1187	pseudouridine synthase activity
MW696_RS09255	COG2244	polysaccharide biosynthetic process
MW696_RS09260	COG2081	HI0933 family
MW696_RS09270	COG1349	DNA-binding transcription factor activity
MW696_RS09280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MW696_RS09295	COG0471	metal ion transport
MW696_RS09300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MW696_RS09310	COG0457	Tetratricopeptide repeat
MW696_RS09320	COG5578	integral membrane protein
MW696_RS09325	COG0673	inositol 2-dehydrogenase activity
MW696_RS09330	COG1653	transport
MW696_RS09335	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MW696_RS09340	COG4209	transmembrane transport
MW696_RS09345	COG2207	Transcriptional regulator
MW696_RS09350	COG1653	transport
MW696_RS09355	COG0395	ABC-type sugar transport system, permease component
MW696_RS09360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MW696_RS09365	COG1073	alpha beta
MW696_RS09375	COG0583	DNA-binding transcription factor activity
MW696_RS09380	COG0346	lactoylglutathione lyase activity
MW696_RS09385	COG0495	leucyl-tRNA aminoacylation
MW696_RS09395	COG2814	Major facilitator Superfamily
MW696_RS09410	COG2433	Pfam Transposase IS66
MW696_RS09415	COG0577	efflux transmembrane transporter activity
MW696_RS09420	COG1136	(ABC) transporter
MW696_RS09430	COG1131	(ABC) transporter
MW696_RS09435	COG1725	Transcriptional regulator
MW696_RS09450	COG1242	4 iron, 4 sulfur cluster binding
MW696_RS09455	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MW696_RS09460	COG1301	dicarboxylic acid transport
MW696_RS09470	COG2267	carboxylic ester hydrolase activity
MW696_RS09475	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MW696_RS09480	COG0671	phosphoesterase, PA-phosphatase related
MW696_RS09485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_RS09485	COG0438	transferase activity, transferring glycosyl groups
MW696_RS09490	COG0367	asparagine synthase
MW696_RS09495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MW696_RS09500	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MW696_RS09510	COG1506	peptidase
MW696_RS09515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MW696_RS09520	COG1116	anion transmembrane transporter activity
MW696_RS09525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MW696_RS09530	COG0494	nUDIX hydrolase
MW696_RS09545	COG4824	toxin secretion phage lysis holin
MW696_RS09550	COG0783	Belongs to the Dps family
MW696_RS09565	COG1854	S-ribosylhomocysteine lyase activity
MW696_RS09570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MW696_RS09575	COG0288	reversible hydration of carbon dioxide
MW696_RS09580	COG0803	Belongs to the bacterial solute-binding protein 9 family
MW696_RS09585	COG0254	rRNA binding
MW696_RS09590	COG1271	oxidase subunit
MW696_RS09595	COG1294	oxidase, subunit
MW696_RS09610	COG2079	MmgE PrpD family protein
MW696_RS09615	COG1473	amidohydrolase
MW696_RS09620	COG1126	abc transporter atp-binding protein
MW696_RS09625	COG0765	amino acid transport
MW696_RS09630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_RS09635	COG0456	acetyltransferase
MW696_RS09640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_RS09645	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_RS09655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MW696_RS09660	COG0596	Alpha beta hydrolase
MW696_RS09665	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MW696_RS09670	COG1169	isochorismate synthase
MW696_RS09675	COG1575	Belongs to the MenA family. Type 1 subfamily
MW696_RS09680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MW696_RS09780	COG0789	Transcriptional regulator
MW696_RS09790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MW696_RS09805	COG1609	Transcriptional regulator
MW696_RS09810	COG3859	Proton-coupled thiamine transporter YuaJ
MW696_RS09815	COG3764	Sortase (surface protein transpeptidase)
MW696_RS09830	COG0457	Tetratricopeptide repeat
MW696_RS09835	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MW696_RS09840	COG2318	DinB family
MW696_RS09850	COG1454	alcohol dehydrogenase
MW696_RS09855	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS09860	COG1510	regulation of RNA biosynthetic process
MW696_RS09865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MW696_RS09865	COG1017	nitric oxide dioxygenase activity
MW696_RS09890	COG1397	ADP-ribosylglycohydrolase
MW696_RS09895	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MW696_RS09950	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MW696_RS09965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MW696_RS09970	COG0726	polysaccharide deacetylase
MW696_RS09975	COG1408	metallophosphoesterase
MW696_RS09980	COG1968	undecaprenyl-diphosphatase activity
MW696_RS09985	COG0628	permease
MW696_RS09990	COG0673	inositol 2-dehydrogenase activity
MW696_RS09995	COG0840	transmembrane signaling receptor activity
MW696_RS10000	COG0840	transmembrane signaling receptor activity
MW696_RS10005	COG0840	transmembrane signaling receptor activity
MW696_RS10015	COG2070	2-Nitropropane dioxygenase
MW696_RS10020	COG0432	Pfam Uncharacterised protein family UPF0047
MW696_RS10025	COG0366	Alpha amylase catalytic
MW696_RS10030	COG5297	Belongs to the glycosyl hydrolase family 6
MW696_RS10035	COG1253	flavin adenine dinucleotide binding
MW696_RS10040	COG2738	Putative neutral zinc metallopeptidase
MW696_RS10055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MW696_RS10070	COG0166	Belongs to the GPI family
MW696_RS10075	COG1979	alcohol dehydrogenase
MW696_RS10080	COG2155	Conserved Protein
MW696_RS10085	COG1098	S1 RNA binding domain
MW696_RS10090	COG0436	Aminotransferase
MW696_RS10095	COG1522	sequence-specific DNA binding
MW696_RS10100	COG2267	carboxylic ester hydrolase activity
MW696_RS10110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MW696_RS10125	COG5018	Exonuclease
MW696_RS10130	COG2814	Major facilitator Superfamily
MW696_RS10135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_RS10140	COG3011	Protein conserved in bacteria
MW696_RS10150	COG3290	protein histidine kinase activity
MW696_RS10155	COG4565	transcriptional regulatory protein
MW696_RS10160	COG1744	ABC transporter substrate-binding protein PnrA-like
MW696_RS10165	COG3845	ABC transporter
MW696_RS10170	COG4603	Belongs to the binding-protein-dependent transport system permease family
MW696_RS10175	COG1079	Belongs to the binding-protein-dependent transport system permease family
MW696_RS10180	COG1183	phosphatidylcholine synthase activity
MW696_RS10185	COG0586	Pfam SNARE associated Golgi protein
MW696_RS10190	COG0688	phosphatidylethanolamine metabolic process
MW696_RS10195	COG3493	citrate carrier protein
MW696_RS10205	COG2111	Na H antiporter
MW696_RS10205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MW696_RS10210	COG2111	Na H antiporter
MW696_RS10215	COG1006	Multisubunit Na H antiporter MnhC subunit
MW696_RS10220	COG0651	ATP synthesis coupled electron transport
MW696_RS10225	COG1863	multisubunit Na H antiporter MnhE subunit
MW696_RS10230	COG2212	antiporter activity
MW696_RS10235	COG1320	monovalent cation:proton antiporter activity
MW696_RS10240	COG2050	protein possibly involved in aromatic compounds catabolism
MW696_RS10245	COG2197	response regulator
MW696_RS10250	COG4585	Histidine kinase
MW696_RS10260	COG0142	geranyltranstransferase activity
MW696_RS10275	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MW696_RS10280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MW696_RS10285	COG1335	isochorismatase
MW696_RS10290	COG5506	Protein of unknown function (DUF1694)
MW696_RS10305	COG0628	permease
MW696_RS10310	COG1959	2 iron, 2 sulfur cluster binding
MW696_RS10320	COG1418	mRNA catabolic process
MW696_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS10340	COG1511	domain protein
MW696_RS10345	COG0433	COG0433 Predicted ATPase
MW696_RS10345	COG1674	ftsk spoiiie
MW696_RS10350	COG4499	WXG100 protein secretion system (Wss), protein YukC
MW696_RS10355	COG5417	Belongs to the EsaB family
MW696_RS10360	COG4842	Belongs to the WXG100 family
MW696_RS10365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MW696_RS10365	COG2508	Transcriptional regulator
MW696_RS10370	COG0686	Belongs to the AlaDH PNT family
MW696_RS10375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MW696_RS10380	COG1268	BioY protein
MW696_RS10385	COG2056	Na+-H+ antiporter family
MW696_RS10390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MW696_RS10395	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MW696_RS10400	COG3584	3D domain protein
MW696_RS10415	COG1252	NADH dehydrogenase
MW696_RS10420	COG0492	ferredoxin-NADP+ reductase activity
MW696_RS10450	COG0316	Belongs to the HesB IscA family
MW696_RS10455	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MW696_RS10460	COG4844	belongs to the
MW696_RS10465	COG1252	NADH dehydrogenase
MW696_RS10480	COG0457	Tetratricopeptide repeat
MW696_RS10485	COG3479	Phenolic acid decarboxylase
MW696_RS10495	COG4837	Protein of unknown function (DUF1462)
MW696_RS10505	COG4946	Tricorn protease homolog
MW696_RS10505	COG0823	Involved in the tonB-independent uptake of proteins
MW696_RS10505	COG1506	peptidase
MW696_RS10510	COG0083	homoserine kinase activity
MW696_RS10515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MW696_RS10520	COG0460	homoserine dehydrogenase
MW696_RS10525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_RS10530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MW696_RS10535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MW696_RS10540	COG0647	UMP catabolic process
MW696_RS10545	COG2445	Protein of unknown function DUF86
MW696_RS10550	COG4470	Protein conserved in bacteria
MW696_RS10565	COG0739	heme binding
MW696_RS10575	COG3377	Domain of unknown function (DUF1805)
MW696_RS10580	COG0737	Belongs to the 5'-nucleotidase family
MW696_RS10585	COG0730	response to heat
MW696_RS10590	COG1801	Protein of unknown function DUF72
MW696_RS10600	COG3226	Transcriptional regulator
MW696_RS10605	COG2814	Major facilitator Superfamily
MW696_RS10610	COG2356	endonuclease I
MW696_RS10630	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MW696_RS10635	COG2068	MobA-Related Protein
MW696_RS10640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MW696_RS10645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MW696_RS10665	COG0719	Fe-S assembly protein
MW696_RS10670	COG0822	iron-sulfur transferase activity
MW696_RS10675	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MW696_RS10680	COG0719	Fe-S assembly protein
MW696_RS10685	COG0396	ATPase activity
MW696_RS10700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MW696_RS10705	COG1464	Belongs to the NlpA lipoprotein family
MW696_RS10710	COG2011	ABC-type metal ion transport system permease component
MW696_RS10715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MW696_RS10725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS10730	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MW696_RS10740	COG0509	glycine decarboxylation via glycine cleavage system
MW696_RS10745	COG1393	Belongs to the ArsC family
MW696_RS10750	COG1960	acyl-CoA dehydrogenase activity
MW696_RS10755	COG0183	Belongs to the thiolase family
MW696_RS10760	COG1250	3-hydroxyacyl-CoA dehydrogenase
MW696_RS10760	COG1024	Enoyl-CoA hydratase
MW696_RS10775	COG5577	PFAM Coat F domain
MW696_RS10790	COG1120	ATPase activity
MW696_RS10795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS10800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS10805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS10820	COG1686	Belongs to the peptidase S11 family
MW696_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS10830	COG0783	Belongs to the Dps family
MW696_RS10835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_RS10840	COG0745	RESPONSE REGULATOR receiver
MW696_RS10845	COG2770	Histidine kinase
MW696_RS10845	COG2205	protein histidine kinase activity
MW696_RS10855	COG1309	transcriptional regulator
MW696_RS10860	COG0114	fumarate hydratase activity
MW696_RS10870	COG0697	spore germination
MW696_RS10875	COG0814	amino acid
MW696_RS10890	COG2197	response regulator
MW696_RS10895	COG4585	Histidine kinase
MW696_RS10900	COG4758	membrane
MW696_RS10910	COG1842	Phage shock protein A
MW696_RS10915	COG4758	membrane
MW696_RS10920	COG4677	pectinesterase activity
MW696_RS10930	COG0297	glycogen (starch) synthase activity
MW696_RS10935	COG2096	Adenosyltransferase
MW696_RS10940	COG1120	ATPase activity
MW696_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS10950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS10955	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS10960	COG2258	MOSC domain
MW696_RS10965	COG0583	DNA-binding transcription factor activity
MW696_RS10975	COG2721	sulfolactate sulfo-lyase activity
MW696_RS10980	COG0246	Mannitol dehydrogenase
MW696_RS10985	COG1609	Transcriptional regulator
MW696_RS10990	COG2211	Major facilitator Superfamily
MW696_RS10995	COG1904	glucuronate isomerase
MW696_RS11000	COG2205	protein histidine kinase activity
MW696_RS11005	COG0745	RESPONSE REGULATOR receiver
MW696_RS11010	COG1120	ATPase activity
MW696_RS11015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS11020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS11025	COG0531	amino acid
MW696_RS11035	COG1988	membrane-bound metal-dependent
MW696_RS11040	COG1368	sulfuric ester hydrolase activity
MW696_RS11045	COG2814	Major facilitator Superfamily
MW696_RS11050	COG0656	L-ascorbic acid biosynthetic process
MW696_RS11055	COG1940	carbohydrate kinase activity
MW696_RS11065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MW696_RS11075	COG3973	AAA domain
MW696_RS11080	COG2860	membrane
MW696_RS11085	COG0456	acetyltransferase
MW696_RS11085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MW696_RS11090	COG0456	acetyltransferase
MW696_RS11095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MW696_RS11100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MW696_RS11105	COG2217	Heavy metal translocating P-type atpase
MW696_RS11120	COG1175	transmembrane transport
MW696_RS11125	COG0395	ABC-type sugar transport system, permease component
MW696_RS11130	COG1501	Belongs to the glycosyl hydrolase 31 family
MW696_RS11135	COG1472	Belongs to the glycosyl hydrolase 3 family
MW696_RS11140	COG1121	(ABC) transporter
MW696_RS11145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MW696_RS11150	COG0803	Belongs to the bacterial solute-binding protein 9 family
MW696_RS11160	COG1105	Belongs to the carbohydrate kinase PfkB family
MW696_RS11165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_RS11165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS11165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MW696_RS11180	COG2217	Heavy metal translocating P-type atpase
MW696_RS11185	COG2608	mercury ion transmembrane transporter activity
MW696_RS11190	COG1937	Protein conserved in bacteria
MW696_RS11195	COG0693	protein deglycase activity
MW696_RS11200	COG1349	DNA-binding transcription factor activity
MW696_RS11205	COG1070	Carbohydrate kinase
MW696_RS11210	COG4952	isomerase
MW696_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS11220	COG3347	Dehydrogenase
MW696_RS11225	COG2814	Major facilitator Superfamily
MW696_RS11230	COG3340	Belongs to the peptidase S51 family
MW696_RS11235	COG2814	Major facilitator Superfamily
MW696_RS11240	COG1846	Transcriptional regulator
MW696_RS11245	COG1819	glycosyl
MW696_RS11250	COG0673	inositol 2-dehydrogenase activity
MW696_RS11255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MW696_RS11260	COG1054	Belongs to the UPF0176 family
MW696_RS11270	COG1191	sigma factor activity
MW696_RS11280	COG2140	Oxalate decarboxylase
MW696_RS11295	COG5520	Belongs to the glycosyl hydrolase 30 family
MW696_RS11300	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_RS11310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MW696_RS11315	COG0557	exoribonuclease II activity
MW696_RS11320	COG1647	Serine aminopeptidase, S33
MW696_RS11325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MW696_RS11330	COG2002	toxin-antitoxin pair type II binding
MW696_RS11335	COG1476	TRANSCRIPTIONal
MW696_RS11340	COG1396	sequence-specific DNA binding
MW696_RS11345	COG1396	sequence-specific DNA binding
MW696_RS11350	COG1174	glycine betaine transport
MW696_RS11355	COG1732	Glycine betaine
MW696_RS11360	COG1174	glycine betaine transport
MW696_RS11365	COG0517	IMP dehydrogenase activity
MW696_RS11365	COG1125	glycine betaine transport
MW696_RS11370	COG1510	regulation of RNA biosynthetic process
MW696_RS11375	COG2095	MarC family integral membrane protein
MW696_RS11380	COG3064	Membrane
MW696_RS11385	COG4640	response to antibiotic
MW696_RS11390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS11400	COG0148	phosphopyruvate hydratase activity
MW696_RS11405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MW696_RS11410	COG0149	triose-phosphate isomerase activity
MW696_RS11415	COG0126	phosphoglycerate kinase activity
MW696_RS11420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MW696_RS11425	COG2390	Transcriptional regulator
MW696_RS11435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_RS11440	COG1113	amino acid transport
MW696_RS11450	COG1881	PFAM PEBP family protein
MW696_RS11460	COG4585	Histidine kinase
MW696_RS11465	COG2197	response regulator
MW696_RS11475	COG1131	(ABC) transporter
MW696_RS11485	COG4978	Transcriptional regulator
MW696_RS11485	COG0789	Transcriptional regulator
MW696_RS11495	COG1556	Lactate utilization protein
MW696_RS11500	COG1139	Iron-sulfur cluster binding protein
MW696_RS11505	COG0247	lactate metabolic process
MW696_RS11510	COG2186	Transcriptional regulator
MW696_RS11515	COG1620	l-lactate permease
MW696_RS11520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MW696_RS11530	COG5039	Polysaccharide pyruvyl transferase
MW696_RS11535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MW696_RS11540	COG0110	maltose O-acetyltransferase activity
MW696_RS11545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MW696_RS11550	COG2244	polysaccharide biosynthetic process
MW696_RS11555	COG1216	Glycosyl transferase, family 2
MW696_RS11560	COG5039	Polysaccharide pyruvyl transferase
MW696_RS11565	COG1216	Glycosyl transferase, family 2
MW696_RS11575	COG0438	transferase activity, transferring glycosyl groups
MW696_RS11580	COG1215	transferase activity, transferring glycosyl groups
MW696_RS11585	COG0438	transferase activity, transferring glycosyl groups
MW696_RS11590	COG1086	Polysaccharide biosynthesis protein
MW696_RS11595	COG0489	protein tyrosine kinase activity
MW696_RS11600	COG3944	biosynthesis protein
MW696_RS11605	COG1396	sequence-specific DNA binding
MW696_RS11610	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_RS11615	COG2271	Major facilitator Superfamily
MW696_RS11625	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MW696_RS11635	COG1454	alcohol dehydrogenase
MW696_RS11640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MW696_RS11650	COG1733	regulation of RNA biosynthetic process
MW696_RS11655	COG1902	pentaerythritol trinitrate reductase activity
MW696_RS11660	COG1621	beta-fructofuranosidase activity
MW696_RS11665	COG1621	beta-fructofuranosidase activity
MW696_RS11685	COG0457	Tetratricopeptide repeat
MW696_RS11690	COG0457	Tetratricopeptide repeat
MW696_RS11695	COG5444	nuclease activity
MW696_RS11730	COG5632	N-Acetylmuramoyl-L-alanine amidase
MW696_RS11730	COG3409	Peptidoglycan-binding domain 1 protein
MW696_RS11730	COG1388	LysM domain
MW696_RS11750	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_RS11850	COG0582	viral genome integration into host DNA
MW696_RS11950	COG3584	3D domain protein
MW696_RS11955	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MW696_RS11980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_RS11995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MW696_RS12005	COG1780	Probably involved in ribonucleotide reductase function
MW696_RS12020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MW696_RS12040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_RS12040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MW696_RS12175	COG4974	Belongs to the 'phage' integrase family
MW696_RS12185	COG0740	serine-type endopeptidase activity
MW696_RS12195	COG1611	Belongs to the LOG family
MW696_RS12200	COG1694	Mazg nucleotide pyrophosphohydrolase
MW696_RS12205	COG1078	dGTPase activity
MW696_RS12210	COG0659	secondary active sulfate transmembrane transporter activity
MW696_RS12215	COG0288	reversible hydration of carbon dioxide
MW696_RS12220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_RS12225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MW696_RS12230	COG0640	Transcriptional regulator
MW696_RS12235	COG0577	efflux transmembrane transporter activity
MW696_RS12240	COG1136	(ABC) transporter
MW696_RS12245	COG5002	protein histidine kinase activity
MW696_RS12250	COG0745	RESPONSE REGULATOR receiver
MW696_RS12255	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MW696_RS12260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS12265	COG1481	regulation of sporulation
MW696_RS12270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MW696_RS12275	COG1660	Displays ATPase and GTPase activities
MW696_RS12280	COG1051	belongs to the nudix hydrolase family
MW696_RS12285	COG0492	ferredoxin-NADP+ reductase activity
MW696_RS12290	COG0457	Tetratricopeptide repeat
MW696_RS12295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MW696_RS12295	COG0140	phosphoribosyl-ATP diphosphatase activity
MW696_RS12300	COG0107	imidazoleglycerol-phosphate synthase activity
MW696_RS12305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MW696_RS12310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MW696_RS12315	COG0131	Imidazoleglycerol-phosphate dehydratase
MW696_RS12320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MW696_RS12325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MW696_RS12330	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MW696_RS12335	COG4990	cell redox homeostasis
MW696_RS12340	COG3858	chitin binding
MW696_RS12345	COG5297	Belongs to the glycosyl hydrolase family 6
MW696_RS12350	COG0110	maltose O-acetyltransferase activity
MW696_RS12355	COG0546	phosphoglycolate phosphatase activity
MW696_RS12360	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MW696_RS12365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MW696_RS12370	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MW696_RS12375	COG1846	Transcriptional regulator
MW696_RS12380	COG2814	Major facilitator Superfamily
MW696_RS12385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MW696_RS12390	COG1950	PFAM Membrane protein of
MW696_RS12395	COG1983	PspC domain protein
MW696_RS12400	COG3595	metallopeptidase activity
MW696_RS12415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MW696_RS12420	COG0556	nucleotide-excision repair
MW696_RS12425	COG4897	Protein conserved in bacteria
MW696_RS12435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_RS12445	COG0793	Belongs to the peptidase S41A family
MW696_RS12445	COG3409	Peptidoglycan-binding domain 1 protein
MW696_RS12450	COG0473	3-isopropylmalate dehydrogenase activity
MW696_RS12455	COG0791	NLP P60 protein
MW696_RS12455	COG3883	PFAM NLP P60 protein
MW696_RS12460	COG2177	Part of the ABC transporter FtsEX involved in
MW696_RS12465	COG2884	Cell division ATP-binding protein ftsE
MW696_RS12470	COG2010	Cytochrome c
MW696_RS12475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_RS12485	COG0653	protein targeting
MW696_RS12490	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MW696_RS12505	COG1516	flagellar protein fliS
MW696_RS12510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MW696_RS12515	COG1334	flagellar protein FlaG
MW696_RS12520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MW696_RS12525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MW696_RS12530	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MW696_RS12540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MW696_RS12545	COG1256	bacterial-type flagellum assembly
MW696_RS12545	COG4786	Flagellar basal body rod
MW696_RS12550	COG3418	PFAM FlgN family protein
MW696_RS12555	COG2747	anti-sigma28 factor FlgM
MW696_RS12565	COG1040	competence protein
MW696_RS12575	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MW696_RS12580	COG1307	EDD domain protein, DegV family
MW696_RS12585	COG2197	response regulator
MW696_RS12590	COG4585	Histidine kinase
MW696_RS12595	COG1739	Uncharacterized protein family UPF0029
MW696_RS12600	COG1316	TRANSCRIPTIONal
MW696_RS12605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MW696_RS12610	COG0438	transferase activity, transferring glycosyl groups
MW696_RS12615	COG1215	transferase activity, transferring glycosyl groups
MW696_RS12620	COG3206	protein involved in exopolysaccharide biosynthesis
MW696_RS12625	COG3307	-O-antigen
MW696_RS12630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MW696_RS12635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MW696_RS12640	COG0297	glycogen (starch) synthase activity
MW696_RS12640	COG0438	transferase activity, transferring glycosyl groups
MW696_RS12645	COG2244	polysaccharide biosynthetic process
MW696_RS12655	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_RS12655	COG2247	cell wall binding repeat
MW696_RS12660	COG2385	sporulation resulting in formation of a cellular spore
MW696_RS12660	COG2247	cell wall binding repeat
MW696_RS12670	COG1316	TRANSCRIPTIONal
MW696_RS12675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MW696_RS12680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MW696_RS12685	COG1134	teichoic acid transport
MW696_RS12690	COG1682	transport, permease protein
MW696_RS12695	COG1215	transferase activity, transferring glycosyl groups
MW696_RS12710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MW696_RS12720	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MW696_RS12725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MW696_RS12735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MW696_RS12740	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MW696_RS12745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MW696_RS12750	COG4193	domain, Protein
MW696_RS12755	COG1482	cell wall glycoprotein biosynthetic process
MW696_RS12765	COG1328	CTP reductase activity
MW696_RS12775	COG0800	Aldolase
MW696_RS12780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_RS12785	COG1609	Transcriptional regulator
MW696_RS12790	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MW696_RS12795	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS12800	COG1063	alcohol dehydrogenase
MW696_RS12810	COG2814	Major facilitator Superfamily
MW696_RS12815	COG1316	TRANSCRIPTIONal
MW696_RS12820	COG0561	phosphatase activity
MW696_RS12825	COG0791	NLP P60 protein
MW696_RS12835	COG2843	Capsule synthesis protein
MW696_RS12845	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MW696_RS12850	COG1609	Transcriptional regulator
MW696_RS12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_RS12860	COG1869	D-ribose catabolic process
MW696_RS12865	COG1129	ABC transporter
MW696_RS12870	COG1172	Belongs to the binding-protein-dependent transport system permease family
MW696_RS12875	COG1879	ABC-type sugar transport system periplasmic component
MW696_RS12880	COG0583	DNA-binding transcription factor activity
MW696_RS12885	COG2226	methyltransferase
MW696_RS12890	COG3527	Alpha-acetolactate decarboxylase
MW696_RS12895	COG0028	Belongs to the TPP enzyme family
MW696_RS12900	COG0583	DNA-binding transcription factor activity
MW696_RS12910	COG1522	sequence-specific DNA binding
MW696_RS12915	COG2059	Chromate
MW696_RS12920	COG2059	Chromate
MW696_RS12925	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MW696_RS12930	COG4464	protein tyrosine phosphatase activity
MW696_RS12935	COG3944	biosynthesis protein
MW696_RS12945	COG4715	Zinc finger, swim domain protein
MW696_RS12950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MW696_RS12955	COG0831	urea catabolic process
MW696_RS12960	COG0832	Belongs to the urease beta subunit family
MW696_RS12965	COG0804	urea catabolic process
MW696_RS12970	COG0561	phosphatase activity
MW696_RS12975	COG1349	DNA-binding transcription factor activity
MW696_RS12980	COG0629	single-stranded DNA binding
MW696_RS12995	COG1970	mechanosensitive ion channel activity
MW696_RS13000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MW696_RS13005	COG4786	Flagellar basal body rod
MW696_RS13010	COG4786	Flagellar basal body rod
MW696_RS13015	COG1077	Cell shape determining protein MreB Mrl
MW696_RS13020	COG1609	Transcriptional regulator
MW696_RS13025	COG1846	Transcriptional regulator
MW696_RS13030	COG2814	Major facilitator Superfamily
MW696_RS13035	COG0671	phosphoesterase, PA-phosphatase related
MW696_RS13040	COG1227	inorganic diphosphatase activity
MW696_RS13045	COG3546	catalase activity
MW696_RS13050	COG3361	conserved protein (COG2071)
MW696_RS13055	COG0517	IMP dehydrogenase activity
MW696_RS13060	COG0598	Magnesium transport protein CorA
MW696_RS13065	COG1253	flavin adenine dinucleotide binding
MW696_RS13070	COG0004	ammonium transporteR
MW696_RS13075	COG0347	Belongs to the P(II) protein family
MW696_RS13085	COG0740	serine-type endopeptidase activity
MW696_RS13095	COG0739	heme binding
MW696_RS13100	COG1247	-acetyltransferase
MW696_RS13110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MW696_RS13115	COG0477	Major facilitator Superfamily
MW696_RS13120	COG3251	PFAM MbtH domain protein
MW696_RS13125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS13130	COG3433	isochorismatase activity
MW696_RS13130	COG1535	isochorismatase
MW696_RS13135	COG1021	2,3-dihydroxybenzoate-AMP ligase
MW696_RS13140	COG1169	isochorismate synthase
MW696_RS13145	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS13150	COG2819	hydrolase of the alpha beta superfamily
MW696_RS13155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS13160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS13165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS13170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS13170	COG2207	Transcriptional regulator
MW696_RS13180	COG2910	NAD(P)H-binding
MW696_RS13185	COG1959	2 iron, 2 sulfur cluster binding
MW696_RS13195	COG1994	Peptidase M50
MW696_RS13200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MW696_RS13205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MW696_RS13210	COG2223	nitrite transmembrane transporter activity
MW696_RS13220	COG2304	oxidoreductase activity
MW696_RS13225	COG2304	oxidoreductase activity
MW696_RS13230	COG2385	sporulation resulting in formation of a cellular spore
MW696_RS13235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MW696_RS13245	COG4836	Membrane
MW696_RS13250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MW696_RS13255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MW696_RS13260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MW696_RS13265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MW696_RS13270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MW696_RS13275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MW696_RS13280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MW696_RS13295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MW696_RS13300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MW696_RS13305	COG4475	Protein of unknown function (DUF436)
MW696_RS13310	COG0698	ribose 5-phosphate isomerase
MW696_RS13315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MW696_RS13320	COG1971	Probably functions as a manganese efflux pump
MW696_RS13325	COG0009	L-threonylcarbamoyladenylate synthase
MW696_RS13330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MW696_RS13340	COG0738	Major facilitator superfamily
MW696_RS13345	COG0673	inositol 2-dehydrogenase activity
MW696_RS13350	COG0561	phosphatase activity
MW696_RS13355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MW696_RS13360	COG1609	Transcriptional regulator
MW696_RS13365	COG2890	protein-(glutamine-N5) methyltransferase activity
MW696_RS13370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MW696_RS13375	COG0346	lactoylglutathione lyase activity
MW696_RS13380	COG0789	Transcriptional regulator
MW696_RS13385	COG0679	Auxin Efflux Carrier
MW696_RS13390	COG0281	malic enzyme
MW696_RS13395	COG1435	thymidine kinase activity
MW696_RS13405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MW696_RS13410	COG1494	fructose-1,6-bisphosphatase
MW696_RS13415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MW696_RS13420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MW696_RS13425	COG0191	fructose-bisphosphate aldolase activity
MW696_RS13430	COG2204	response regulator
MW696_RS13435	COG4821	SIS domain
MW696_RS13440	COG0504	CTP synthase activity
MW696_RS13445	COG3343	RNA polymerase activity
MW696_RS13450	COG1960	acyl-CoA dehydrogenase activity
MW696_RS13455	COG1960	acyl-CoA dehydrogenase activity
MW696_RS13460	COG1250	3-hydroxyacyl-CoA dehydrogenase
MW696_RS13465	COG0183	Belongs to the thiolase family
MW696_RS13470	COG0247	lactate metabolic process
MW696_RS13470	COG2181	nitrate reductase activity
MW696_RS13490	COG0018	arginyl-trna synthetase
MW696_RS13495	COG4506	Protein conserved in bacteria
MW696_RS13500	COG0010	Belongs to the arginase family
MW696_RS13505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MW696_RS13510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_RS13520	COG1994	Peptidase M50
MW696_RS13525	COG1942	4-Oxalocrotonate Tautomerase
MW696_RS13535	COG3465	dGTPase activity
MW696_RS13540	COG1078	dGTPase activity
MW696_RS13545	COG4844	belongs to the
MW696_RS13570	COG2814	Major facilitator Superfamily
MW696_RS13595	COG1414	Transcriptional regulator
MW696_RS13605	COG0280	phosphate acetyltransferase
MW696_RS13610	COG3253	May function as heme-dependent peroxidase
MW696_RS13635	COG1131	(ABC) transporter
MW696_RS13645	COG2197	response regulator
MW696_RS13650	COG2363	Small membrane protein
MW696_RS13655	COG2233	PERMEase
MW696_RS13665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MW696_RS13670	COG1216	Glycosyl transferase, family 2
MW696_RS13675	COG0351	phosphomethylpyrimidine kinase
MW696_RS13685	COG1621	beta-fructofuranosidase activity
MW696_RS13690	COG1263	PTS System
MW696_RS13690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS13695	COG3711	transcriptional antiterminator
MW696_RS13705	COG1404	Belongs to the peptidase S8 family
MW696_RS13715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_RS13725	COG0778	Nitroreductase
MW696_RS13730	COG1473	amidohydrolase
MW696_RS13735	COG0772	Belongs to the SEDS family
MW696_RS13740	COG0772	Belongs to the SEDS family
MW696_RS13745	COG3314	Sporulation integral membrane protein YlbJ
MW696_RS13785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MW696_RS13795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MW696_RS13800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MW696_RS13805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_RS13820	COG0655	NAD(P)H dehydrogenase (quinone) activity
MW696_RS13825	COG3162	membrane
MW696_RS13830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_RS13835	COG1070	Carbohydrate kinase
MW696_RS13840	COG2115	Belongs to the xylose isomerase family
MW696_RS13850	COG0352	thiamine-phosphate diphosphorylase activity
MW696_RS13855	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MW696_RS13860	COG0583	DNA-binding transcription factor activity
MW696_RS13875	COG1380	Effector of murein hydrolase LrgA
MW696_RS13880	COG1346	cytolysis
MW696_RS13885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_RS13890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MW696_RS13895	COG0346	lactoylglutathione lyase activity
MW696_RS13900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MW696_RS13905	COG1442	glycosyl transferase family 8
MW696_RS13910	COG5522	Integral membrane protein (intg_mem_TP0381)
MW696_RS13915	COG2271	Major facilitator Superfamily
MW696_RS13920	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_RS13925	COG0800	Aldolase
MW696_RS13930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_RS13935	COG1414	Transcriptional regulator
MW696_RS13940	COG2234	aminopeptidase activity
MW696_RS13960	COG0477	Major facilitator Superfamily
MW696_RS13965	COG1335	isochorismatase
MW696_RS13970	COG2357	RelA SpoT domain protein
MW696_RS13985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS13990	COG1696	Membrane protein involved in D-alanine export
MW696_RS13995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MW696_RS14000	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MW696_RS14005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MW696_RS14010	COG2814	Major facilitator Superfamily
MW696_RS14015	COG1486	melibiose metabolic process
MW696_RS14020	COG1447	Phosphotransferase system cellobiose-specific component IIA
MW696_RS14025	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_RS14030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_RS14035	COG3711	transcriptional antiterminator
MW696_RS14035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS14040	COG2094	Belongs to the DNA glycosylase MPG family
MW696_RS14065	COG0372	Belongs to the citrate synthase family
MW696_RS14070	COG2079	MmgE PrpD family protein
MW696_RS14075	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MW696_RS14080	COG1132	(ABC) transporter
MW696_RS14085	COG2755	lipolytic protein G-D-S-L family
MW696_RS14105	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MW696_RS14110	COG1131	(ABC) transporter
MW696_RS14130	COG1595	DNA-templated transcription, initiation
MW696_RS14135	COG2814	Major facilitator Superfamily
MW696_RS14145	COG0753	catalase activity
MW696_RS14155	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MW696_RS14165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MW696_RS14170	COG2311	Membrane
MW696_RS14175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MW696_RS14180	COG4988	ABC transporter
MW696_RS14185	COG1294	oxidase, subunit
MW696_RS14190	COG1271	oxidase subunit
MW696_RS14195	COG3001	Fructosamine kinase
MW696_RS14200	COG2116	formate transmembrane transporter activity
MW696_RS14210	COG0281	malic enzyme
MW696_RS14215	COG1757	Na H antiporter
MW696_RS14220	COG1027	Aspartate ammonia-lyase
MW696_RS14225	COG0252	asparaginase activity
MW696_RS14230	COG1396	sequence-specific DNA binding
MW696_RS14235	COG2706	6-phosphogluconolactonase activity
MW696_RS14240	COG0745	RESPONSE REGULATOR receiver
MW696_RS14255	COG5294	Protein conserved in bacteria
MW696_RS14270	COG0726	polysaccharide deacetylase
MW696_RS14275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS14290	COG3493	citrate carrier protein
MW696_RS14295	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_RS14315	COG5444	nuclease activity
MW696_RS14325	COG1368	sulfuric ester hydrolase activity
MW696_RS14340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_RS14345	COG1438	arginine binding
MW696_RS14350	COG2235	arginine
MW696_RS14355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MW696_RS14365	COG0549	Belongs to the carbamate kinase family
MW696_RS14375	COG2205	protein histidine kinase activity
MW696_RS14380	COG2723	6-phospho-beta-galactosidase activity
MW696_RS14385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MW696_RS14395	COG1595	DNA-templated transcription, initiation
MW696_RS14405	COG2195	Cleaves the N-terminal amino acid of tripeptides
MW696_RS14415	COG1621	beta-fructofuranosidase activity
MW696_RS14420	COG2223	nitrite transmembrane transporter activity
MW696_RS14425	COG1609	Transcriptional regulator
MW696_RS14440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MW696_RS14445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MW696_RS14450	COG0463	Glycosyl transferase, family 2
MW696_RS14455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_RS14465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MW696_RS14470	COG1476	TRANSCRIPTIONal
MW696_RS14475	COG0693	protein deglycase activity
MW696_RS14475	COG0753	catalase activity
MW696_RS14480	COG2851	Citrate transporter
MW696_RS14485	COG2723	6-phospho-beta-galactosidase activity
MW696_RS14495	COG3711	transcriptional antiterminator
MW696_RS14500	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MW696_RS14505	COG1122	ATPase activity
MW696_RS14510	COG4721	ABC-type cobalt transport system, permease component
MW696_RS14515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MW696_RS14530	COG2224	Isocitrate lyase
MW696_RS14535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MW696_RS14545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MW696_RS14550	COG0577	efflux transmembrane transporter activity
MW696_RS14555	COG1136	(ABC) transporter
MW696_RS14560	COG2205	protein histidine kinase activity
MW696_RS14565	COG0745	RESPONSE REGULATOR receiver
MW696_RS14570	COG2723	6-phospho-beta-galactosidase activity
MW696_RS14575	COG1263	PTS System
MW696_RS14575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS14575	COG2190	(PTS) system
MW696_RS14585	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MW696_RS14600	COG0513	Belongs to the DEAD box helicase family
MW696_RS14605	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MW696_RS14610	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MW696_RS14615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MW696_RS14620	COG2390	Transcriptional regulator
MW696_RS14625	COG0457	Tetratricopeptide repeat
MW696_RS14630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MW696_RS14635	COG3706	GGDEF domain
MW696_RS14645	COG1215	transferase activity, transferring glycosyl groups
MW696_RS14655	COG3977	Valine--pyruvate aminotransferase
MW696_RS14670	COG1181	Belongs to the D-alanine--D-alanine ligase family
MW696_RS14680	COG0191	fructose-bisphosphate aldolase activity
MW696_RS14685	COG1082	Xylose isomerase domain protein TIM barrel
MW696_RS14690	COG1082	Xylose isomerase domain protein TIM barrel
MW696_RS14695	COG0673	inositol 2-dehydrogenase activity
MW696_RS14700	COG2814	Major facilitator Superfamily
MW696_RS14705	COG1082	Xylose isomerase domain protein TIM barrel
MW696_RS14710	COG3962	Belongs to the TPP enzyme family
MW696_RS14715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MW696_RS14720	COG3718	enzyme involved in inositol metabolism
MW696_RS14725	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS14730	COG1349	DNA-binding transcription factor activity
MW696_RS14735	COG0667	Aldo Keto reductase
MW696_RS14740	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_RS14745	COG2271	Major facilitator Superfamily
MW696_RS14750	COG0326	Molecular chaperone. Has ATPase activity
MW696_RS14755	COG0488	(ABC) transporter
MW696_RS14760	COG0561	phosphatase activity
MW696_RS14780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MW696_RS14805	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MW696_RS14810	COG0577	efflux transmembrane transporter activity
MW696_RS14815	COG1136	(ABC) transporter
MW696_RS14820	COG2205	protein histidine kinase activity
MW696_RS14825	COG0745	RESPONSE REGULATOR receiver
MW696_RS14835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS14840	COG3867	Arabinogalactan endo-beta-1,4-galactanase
MW696_RS14845	COG1874	Beta-galactosidase
MW696_RS14850	COG3833	ABC-type maltose transport systems, permease component
MW696_RS14855	COG1175	transmembrane transport
MW696_RS14860	COG2182	Extracellular solute-binding protein
MW696_RS14865	COG1609	Transcriptional regulator
MW696_RS14875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_RS14880	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MW696_RS14885	COG1940	carbohydrate kinase activity
MW696_RS14890	COG1802	Transcriptional regulator
MW696_RS14895	COG1070	Carbohydrate kinase
MW696_RS14900	COG2610	gluconate transmembrane transporter activity
MW696_RS14910	COG1454	alcohol dehydrogenase
MW696_RS14910	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS14920	COG0450	alkyl hydroperoxide reductase
MW696_RS14925	COG3634	alkyl hydroperoxide reductase activity
MW696_RS14930	COG1113	amino acid transport
MW696_RS14950	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
MW696_RS14975	COG1131	(ABC) transporter
MW696_RS14980	COG0842	Transport permease protein
MW696_RS14985	COG4585	Histidine kinase
MW696_RS14990	COG2197	response regulator
MW696_RS15000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MW696_RS15005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MW696_RS15020	COG0456	acetyltransferase
MW696_RS15035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MW696_RS15040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MW696_RS15045	COG4853	Protein conserved in bacteria
MW696_RS15050	COG4863	YycH protein
MW696_RS15055	COG5002	protein histidine kinase activity
MW696_RS15060	COG0745	RESPONSE REGULATOR receiver
MW696_RS15085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MW696_RS15095	COG0305	Participates in initiation and elongation during chromosome replication
MW696_RS15105	COG3093	addiction module antidote protein HigA
MW696_RS15110	COG2807	transmembrane transport
MW696_RS15115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MW696_RS15120	COG0363	glucosamine-6-phosphate deaminase activity
MW696_RS15125	COG2188	Transcriptional regulator
MW696_RS15130	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MW696_RS15135	COG1263	PTS System
MW696_RS15135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS15140	COG0359	binds to the 23S rRNA
MW696_RS15145	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MW696_RS15150	COG4241	membrane
MW696_RS15160	COG5577	PFAM Coat F domain
MW696_RS15165	COG0659	secondary active sulfate transmembrane transporter activity
MW696_RS15170	COG2271	Major facilitator Superfamily
MW696_RS15175	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MW696_RS15180	COG0629	single-stranded DNA binding
MW696_RS15185	COG0360	Binds together with S18 to 16S ribosomal RNA
MW696_RS15190	COG0012	GTP binding
MW696_RS15195	COG4481	Protein conserved in bacteria
MW696_RS15200	COG3949	Membrane
MW696_RS15210	COG1475	DNA binding
MW696_RS15215	COG1192	Involved in chromosome partitioning
MW696_RS15220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MW696_RS15225	COG1595	DNA-templated transcription, initiation
MW696_RS15230	COG1475	DNA binding
MW696_RS15235	COG0357	Ribosomal RNA small subunit methyltransferase G
MW696_RS15240	COG0445	tRNA wobble uridine modification
MW696_RS15245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MW696_RS15250	COG1847	R3H domain protein
MW696_RS15255	COG0706	membrane insertase activity
MW696_RS15260	COG0594	ribonuclease P activity
MW696_RS15270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MW696_RS15275	COG0592	DNA-directed DNA polymerase activity
MW696_RS15280	COG2501	S4 domain
MW696_RS15285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MW696_RS15295	COG0187	DNA topoisomerase II activity
MW696_RS15300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MW696_RS15320	COG0516	GMP reductase activity
MW696_RS15320	COG0517	IMP dehydrogenase activity
MW696_RS15325	COG1686	Belongs to the peptidase S11 family
MW696_RS15330	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MW696_RS15335	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MW696_RS15340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MW696_RS15345	COG1929	Belongs to the glycerate kinase type-1 family
MW696_RS15350	COG2610	gluconate transmembrane transporter activity
MW696_RS15355	COG3835	regulator
MW696_RS15360	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MW696_RS15370	COG1309	transcriptional regulator
MW696_RS15375	COG1428	Deoxynucleoside kinase
MW696_RS15380	COG1428	Deoxynucleoside kinase
MW696_RS15385	COG1388	LysM domain
MW696_RS15385	COG3858	chitin binding
MW696_RS15390	COG1335	isochorismatase
MW696_RS15395	COG0590	tRNA wobble adenosine to inosine editing
MW696_RS15405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MW696_RS15410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MW696_RS15415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MW696_RS15435	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MW696_RS15440	COG3853	Toxic anion resistance protein (TelA)
MW696_RS15445	COG1982	Orn Lys Arg decarboxylase major
MW696_RS15450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MW696_RS15455	COG3870	Protein conserved in bacteria
MW696_RS15460	COG1728	Protein conserved in bacteria
MW696_RS15465	COG0470	DNA polymerase III
MW696_RS15470	COG1774	PSP1 C-terminal conserved region
MW696_RS15475	COG4467	Involved in initiation control of chromosome replication
MW696_RS15480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MW696_RS15485	COG2827	Endonuclease containing a URI domain
MW696_RS15490	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MW696_RS15495	COG2002	toxin-antitoxin pair type II binding
MW696_RS15500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_RS15500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MW696_RS15505	COG0084	hydrolase, TatD family'
MW696_RS15510	COG3583	domain protein
MW696_RS15510	COG3584	3D domain protein
MW696_RS15515	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MW696_RS15520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MW696_RS15530	COG4466	Protein conserved in bacteria
MW696_RS15540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MW696_RS15550	COG0251	oxidation-reduction process
MW696_RS15555	COG2088	sporulation resulting in formation of a cellular spore
MW696_RS15560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MW696_RS15565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MW696_RS15570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MW696_RS15575	COG0193	aminoacyl-tRNA hydrolase activity
MW696_RS15585	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MW696_RS15590	COG2002	toxin-antitoxin pair type II binding
MW696_RS15595	COG2244	polysaccharide biosynthetic process
MW696_RS15600	COG3956	TIGRFAM MazG family protein
MW696_RS15605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MW696_RS15620	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MW696_RS15625	COG1098	S1 RNA binding domain
MW696_RS15640	COG2208	phosphoserine phosphatase activity
MW696_RS15645	COG2304	oxidoreductase activity
MW696_RS15650	COG0515	serine threonine protein kinase
MW696_RS15655	COG0037	tRNA processing
MW696_RS15660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MW696_RS15665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MW696_RS15670	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MW696_RS15675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MW696_RS15680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MW696_RS15685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MW696_RS15690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MW696_RS15695	COG0512	Glutamine amidotransferase of anthranilate synthase
MW696_RS15700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MW696_RS15705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MW696_RS15710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MW696_RS15715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MW696_RS15720	COG1396	sequence-specific DNA binding
MW696_RS15725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MW696_RS15730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MW696_RS15755	COG4463	regulation of RNA biosynthetic process
MW696_RS15760	COG3880	PFAM UvrB UvrC protein
MW696_RS15765	COG3869	Catalyzes the specific phosphorylation of arginine residues in
MW696_RS15770	COG0542	response to heat
MW696_RS15775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MW696_RS15780	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MW696_RS15785	COG4956	integral membrane protein (PIN domain superfamily)
MW696_RS15790	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MW696_RS15795	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MW696_RS15800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MW696_RS15805	COG1045	serine acetyltransferase
MW696_RS15810	COG0215	cysteine-tRNA ligase activity
MW696_RS15820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MW696_RS15825	COG3688	RNA-binding protein containing a PIN domain
MW696_RS15835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MW696_RS15845	COG0250	Participates in transcription elongation, termination and antitermination
MW696_RS15850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MW696_RS15855	COG0081	regulation of translation
MW696_RS15860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MW696_RS15865	COG0222	ribosome binding
MW696_RS15870	COG2813	Specifically methylates the guanine in position
MW696_RS15875	COG0085	RNA polymerase activity
MW696_RS15880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MW696_RS15885	COG1358	cellular component organization or biogenesis
MW696_RS15890	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MW696_RS15895	COG0049	tRNA binding
MW696_RS15900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MW696_RS15905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MW696_RS15915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MW696_RS15920	COG0088	Forms part of the polypeptide exit tunnel
MW696_RS15925	COG0089	rRNA binding
MW696_RS15930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MW696_RS15935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MW696_RS15940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MW696_RS15945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MW696_RS15950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MW696_RS15955	COG0255	Belongs to the universal ribosomal protein uL29 family
MW696_RS15960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MW696_RS15965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MW696_RS15970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MW696_RS15975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MW696_RS15980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MW696_RS15985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MW696_RS15990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MW696_RS15995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MW696_RS16000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MW696_RS16010	COG0200	Binds to the 23S rRNA
MW696_RS16015	COG0201	protein transport
MW696_RS16020	COG0563	adenylate kinase activity
MW696_RS16025	COG0024	Methionine aminopeptidase
MW696_RS16030	COG2163	COG2163 Ribosomal protein L14E L6E L27E
MW696_RS16035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MW696_RS16040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MW696_RS16045	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MW696_RS16050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MW696_RS16055	COG0202	RNA polymerase activity
MW696_RS16060	COG0203	ribosomal protein L17
MW696_RS16065	COG1122	ATPase activity
MW696_RS16070	COG1122	ATPase activity
MW696_RS16075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MW696_RS16080	COG0101	tRNA pseudouridine synthase activity
MW696_RS16085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MW696_RS16090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MW696_RS16105	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_RS16110	COG0489	protein tyrosine kinase activity
MW696_RS16120	COG2194	sulfuric ester hydrolase activity
MW696_RS16125	COG0726	polysaccharide deacetylase
MW696_RS16140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MW696_RS16150	COG0385	Bile acid
MW696_RS16155	COG3876	Protein conserved in bacteria
MW696_RS16160	COG1472	Belongs to the glycosyl hydrolase 3 family
MW696_RS16165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MW696_RS16170	COG1263	PTS System
MW696_RS16170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS16175	COG1737	Transcriptional regulator
MW696_RS16180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MW696_RS16185	COG1683	Conserved Protein
MW696_RS16210	COG1595	DNA-templated transcription, initiation
MW696_RS16215	COG5662	AntiSigma factor
MW696_RS16220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MW696_RS16225	COG4856	YbbR-like protein
MW696_RS16230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MW696_RS16235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MW696_RS16240	COG5646	InterPro IPR014922
MW696_RS16245	COG0640	Transcriptional regulator
MW696_RS16250	COG2814	Major facilitator Superfamily
MW696_RS16275	COG1725	Transcriptional regulator
MW696_RS16280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS16300	COG0596	Alpha beta hydrolase
MW696_RS16305	COG0745	RESPONSE REGULATOR receiver
MW696_RS16310	COG0642	Histidine kinase
MW696_RS16315	COG1132	(ABC) transporter
MW696_RS16330	COG1131	(ABC) transporter
MW696_RS16340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MW696_RS16360	COG2312	Erythromycin esterase
MW696_RS16380	COG1011	Hydrolase
MW696_RS16385	COG1113	amino acid transport
MW696_RS16425	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_RS16430	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_RS16435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MW696_RS16445	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_RS16475	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_RS16480	COG2315	Protein conserved in bacteria
MW696_RS16485	COG1331	Highly conserved protein containing a thioredoxin domain
MW696_RS16490	COG3621	Patatin-like phospholipase
MW696_RS16520	COG1733	regulation of RNA biosynthetic process
MW696_RS16525	COG0596	Alpha beta hydrolase
MW696_RS16530	COG2211	Major facilitator Superfamily
MW696_RS16535	COG0860	N-Acetylmuramoyl-L-alanine amidase
MW696_RS16535	COG3103	Sh3 type 3 domain protein
MW696_RS16535	COG4991	sh3 domain protein
MW696_RS16550	COG3764	Sortase (surface protein transpeptidase)
MW696_RS16560	COG2002	toxin-antitoxin pair type II binding
MW696_RS16575	COG0477	Major facilitator Superfamily
MW696_RS16580	COG1794	racemase activity, acting on amino acids and derivatives
MW696_RS16600	COG2226	methyltransferase
MW696_RS16605	COG0076	glutamate decarboxylase activity
MW696_RS16615	COG1846	Transcriptional regulator
MW696_RS16620	COG2409	Drug exporters of the RND superfamily
MW696_RS16620	COG1033	growth of symbiont in host cell
MW696_RS16630	COG0778	Nitroreductase
MW696_RS16635	COG1802	Transcriptional regulator
MW696_RS16640	COG0730	response to heat
MW696_RS16650	COG4682	membrane
MW696_RS16670	COG0697	spore germination
MW696_RS16675	COG1917	Cupin 2, conserved barrel domain protein
MW696_RS16675	COG2207	Transcriptional regulator
MW696_RS16695	COG0371	Dehydrogenase
MW696_RS16705	COG4257	antibiotic catabolic process
MW696_RS16720	COG3394	polysaccharide catabolic process
MW696_RS16725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS16725	COG1263	PTS System
MW696_RS16735	COG0789	Transcriptional regulator
MW696_RS16740	COG0531	amino acid
MW696_RS16745	COG2205	protein histidine kinase activity
MW696_RS16750	COG2304	oxidoreductase activity
MW696_RS16755	COG1115	amino acid carrier protein
MW696_RS16760	COG2066	Belongs to the glutaminase family
MW696_RS16765	COG4191	Histidine kinase
MW696_RS16770	COG0784	Response regulator, receiver
MW696_RS16780	COG3540	Alkaline phosphatase
MW696_RS16785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MW696_RS16790	COG0805	protein transport
MW696_RS16795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MW696_RS16800	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS16805	COG2271	Major facilitator Superfamily
MW696_RS16810	COG4948	Mandelate Racemase Muconate Lactonizing
MW696_RS16815	COG2186	Transcriptional regulator
MW696_RS16820	COG2721	sulfolactate sulfo-lyase activity
MW696_RS16850	COG3173	Aminoglycoside phosphotransferase
MW696_RS16855	COG1846	Transcriptional regulator
MW696_RS16860	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_RS16880	COG0789	Transcriptional regulator
MW696_RS16890	COG0697	spore germination
MW696_RS16900	COG1714	RDD family
MW696_RS16905	COG3012	SEC-C Motif Domain Protein
MW696_RS16905	COG1405	negative regulation of cell septum assembly
MW696_RS16910	COG1131	(ABC) transporter
MW696_RS16935	COG0583	DNA-binding transcription factor activity
MW696_RS16940	COG1942	4-Oxalocrotonate Tautomerase
MW696_RS16945	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS16950	COG4106	trans-aconitate 2-methyltransferase activity
MW696_RS16970	COG0252	asparaginase activity
MW696_RS16975	COG0456	acetyltransferase
MW696_RS16985	COG1164	Oligoendopeptidase f
MW696_RS16990	COG2261	transglycosylase associated protein
MW696_RS17000	COG0247	lactate metabolic process
MW696_RS17005	COG0277	FAD linked oxidase domain protein
MW696_RS17010	COG3591	Belongs to the peptidase S1B family
MW696_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS17025	COG1595	DNA-templated transcription, initiation
MW696_RS17040	COG3773	Cell wall hydrolase
MW696_RS17045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_RS17050	COG3883	PFAM NLP P60 protein
MW696_RS17050	COG0791	NLP P60 protein
MW696_RS17060	COG1131	(ABC) transporter
MW696_RS17065	COG1309	transcriptional regulator
MW696_RS17090	COG2310	stress, protein
MW696_RS17095	COG2310	stress, protein
MW696_RS17100	COG2310	stress, protein
MW696_RS17105	COG0861	Integral membrane protein TerC family
MW696_RS17120	COG1358	cellular component organization or biogenesis
MW696_RS17140	COG3853	Toxic anion resistance protein (TelA)
MW696_RS17145	COG0517	IMP dehydrogenase activity
MW696_RS17145	COG4175	Glycine betaine
MW696_RS17150	COG4176	ABC-type proline glycine betaine transport system permease component
MW696_RS17155	COG2113	Glycine betaine
MW696_RS17160	COG1473	amidohydrolase
MW696_RS17165	COG1288	antiporter activity
MW696_RS17170	COG2223	nitrite transmembrane transporter activity
MW696_RS17175	COG0477	Major facilitator Superfamily
MW696_RS17180	COG0039	L-malate dehydrogenase activity
MW696_RS17185	COG1620	l-lactate permease
MW696_RS17190	COG1280	lysine exporter protein (LysE YggA)
MW696_RS17195	COG1113	amino acid transport
MW696_RS17200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MW696_RS17205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MW696_RS17210	COG3541	Predicted nucleotidyltransferase
MW696_RS17215	COG0506	proline dehydrogenase activity
MW696_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS17225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_RS17230	COG2508	Transcriptional regulator
MW696_RS17235	COG3689	TIGRFAM TIGR03943 family protein
MW696_RS17240	COG0701	Predicted permease
MW696_RS17245	COG3458	cephalosporin-C deacetylase activity
MW696_RS17270	COG0765	amino acid transport
MW696_RS17275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_RS17290	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MW696_RS17295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS17300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS17305	COG1120	ATPase activity
MW696_RS17310	COG3842	ATPase activity
MW696_RS17315	COG2723	6-phospho-beta-galactosidase activity
MW696_RS17340	COG5444	nuclease activity
MW696_RS17360	COG3842	ATPase activity
MW696_RS17365	COG1176	ABC-type spermidine putrescine transport system, permease component I
MW696_RS17375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS17385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MW696_RS17390	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MW696_RS17395	COG0697	spore germination
MW696_RS17400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS17410	COG2819	hydrolase of the alpha beta superfamily
MW696_RS17415	COG2207	Transcriptional regulator
MW696_RS17415	COG3708	Transcriptional regulator
MW696_RS17425	COG2364	Membrane
MW696_RS17450	COG1126	abc transporter atp-binding protein
MW696_RS17455	COG0765	amino acid transport
MW696_RS17460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MW696_RS17465	COG3829	transcription factor binding
MW696_RS17470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MW696_RS17475	COG0833	amino acid
MW696_RS17480	COG0010	Belongs to the arginase family
MW696_RS17485	COG2364	Membrane
MW696_RS17490	COG1846	Transcriptional regulator
MW696_RS17495	COG0456	acetyltransferase
MW696_RS17500	COG2808	Putative FMN-binding domain
MW696_RS17505	COG0583	DNA-binding transcription factor activity
MW696_RS17510	COG0163	prenyltransferase activity
MW696_RS17515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MW696_RS17550	COG5444	nuclease activity
MW696_RS17570	COG2972	Histidine kinase
MW696_RS17575	COG2197	response regulator
MW696_RS17580	COG4213	ABC transporter substrate-binding protein
MW696_RS17590	COG4214	carbohydrate transport
MW696_RS17595	COG2271	Major facilitator Superfamily
MW696_RS17600	COG0456	acetyltransferase
MW696_RS17600	COG1846	Transcriptional regulator
MW696_RS17605	COG1874	Beta-galactosidase
MW696_RS17610	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
MW696_RS17620	COG3104	oligopeptide transport
MW696_RS17625	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_RS17635	COG0697	spore germination
MW696_RS17645	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MW696_RS17650	COG0789	Transcriptional regulator
MW696_RS17655	COG1136	(ABC) transporter
MW696_RS17660	COG0577	efflux transmembrane transporter activity
MW696_RS17665	COG0745	RESPONSE REGULATOR receiver
MW696_RS17670	COG3850	Histidine kinase
MW696_RS17670	COG5002	protein histidine kinase activity
MW696_RS17675	COG5278	phosphoserine phosphatase activity
MW696_RS17675	COG0840	transmembrane signaling receptor activity
MW696_RS17680	COG0527	aspartate kinase activity
MW696_RS17685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS17690	COG4605	iron ion homeostasis
MW696_RS17695	COG4604	ABC transporter, ATP-binding protein
MW696_RS17700	COG4607	ABC-type enterochelin transport system periplasmic component
MW696_RS17705	COG2814	Major facilitator Superfamily
MW696_RS17710	COG1309	transcriptional regulator
MW696_RS17720	COG0778	Nitroreductase
MW696_RS17725	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MW696_RS17730	COG0640	Transcriptional regulator
MW696_RS17735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS17740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MW696_RS17745	COG0531	amino acid
MW696_RS17750	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS17755	COG4221	oxidoreductase activity
MW696_RS17760	COG4549	nuclear export factor GLE1
MW696_RS17765	COG1276	copper resistance
MW696_RS17765	COG2372	response to copper ion
MW696_RS17770	COG1349	DNA-binding transcription factor activity
MW696_RS17775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MW696_RS17780	COG0243	molybdopterin cofactor binding
MW696_RS17785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MW696_RS17790	COG2146	nitrite reductase [NAD(P)H] activity
MW696_RS17795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MW696_RS17795	COG1587	Uroporphyrinogen-III synthase
MW696_RS17800	COG0789	Transcriptional regulator
MW696_RS17815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MW696_RS17825	COG0561	phosphatase activity
MW696_RS17830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MW696_RS17835	COG1914	H( )-stimulated, divalent metal cation uptake system
MW696_RS17840	COG4336	lyase activity
MW696_RS17845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MW696_RS17850	COG1984	allophanate hydrolase subunit 2
MW696_RS17855	COG1414	Transcriptional regulator
MW696_RS17860	COG2755	lipolytic protein G-D-S-L family
MW696_RS17865	COG2213	PTS system mannitol-specific
MW696_RS17870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MW696_RS17875	COG0246	Mannitol dehydrogenase
MW696_RS17880	COG3711	transcriptional antiterminator
MW696_RS17885	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS17890	COG1917	Cupin 2, conserved barrel domain protein
MW696_RS17895	COG3871	stress protein (general stress protein 26)
MW696_RS17910	COG2814	Major facilitator Superfamily
MW696_RS17920	COG1522	sequence-specific DNA binding
MW696_RS17925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MW696_RS17925	COG0551	DNA topoisomerase type I activity
MW696_RS17935	COG0287	Prephenate dehydrogenase
MW696_RS17940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MW696_RS17940	COG0512	Glutamine amidotransferase of anthranilate synthase
MW696_RS17945	COG1605	Chorismate mutase
MW696_RS17950	COG0531	amino acid
MW696_RS17955	COG0028	Belongs to the TPP enzyme family
MW696_RS17965	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS17975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS17980	COG1914	H( )-stimulated, divalent metal cation uptake system
MW696_RS17985	COG2261	transglycosylase associated protein
MW696_RS17990	COG1027	Aspartate ammonia-lyase
MW696_RS17995	COG1819	glycosyl
MW696_RS18000	COG4876	unkown
MW696_RS18005	COG2217	Heavy metal translocating P-type atpase
MW696_RS18020	COG0662	Cupin 2, conserved barrel domain protein
MW696_RS18030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MW696_RS18035	COG3290	protein histidine kinase activity
MW696_RS18040	COG4565	transcriptional regulatory protein
MW696_RS18045	COG1301	dicarboxylic acid transport
MW696_RS18050	COG0628	permease
MW696_RS18060	COG1131	(ABC) transporter
MW696_RS18065	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MW696_RS18075	COG1960	acyl-CoA dehydrogenase activity
MW696_RS18090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MW696_RS18095	COG1181	Belongs to the D-alanine--D-alanine ligase family
MW696_RS18100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MW696_RS18110	COG0513	Belongs to the DEAD box helicase family
MW696_RS18115	COG3402	PFAM membrane-flanked domain
MW696_RS18120	COG3428	Bacterial PH domain
MW696_RS18125	COG0705	Rhomboid family
MW696_RS18130	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MW696_RS18135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MW696_RS18140	COG0864	Transcriptional regulator
MW696_RS18145	COG2337	Toxic component of a toxin-antitoxin (TA) module
MW696_RS18150	COG1366	Belongs to the anti-sigma-factor antagonist family
MW696_RS18155	COG1366	Belongs to the anti-sigma-factor antagonist family
MW696_RS18160	COG2172	sigma factor antagonist activity
MW696_RS18165	COG2208	phosphoserine phosphatase activity
MW696_RS18180	COG1191	sigma factor activity
MW696_RS18185	COG2208	phosphoserine phosphatase activity
MW696_RS18190	COG2183	response to ionizing radiation
MW696_RS18200	COG3091	SprT-like family
MW696_RS18240	COG1476	TRANSCRIPTIONal
MW696_RS18250	COG3239	Fatty acid desaturase
MW696_RS18255	COG1278	Cold shock
MW696_RS18260	COG0582	viral genome integration into host DNA
MW696_RS18270	COG0726	polysaccharide deacetylase
MW696_RS18290	COG0457	Tetratricopeptide repeat
MW696_RS18295	COG0640	Transcriptional regulator
MW696_RS18305	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
MW696_RS18315	COG1733	regulation of RNA biosynthetic process
MW696_RS18320	COG0697	spore germination
MW696_RS18325	COG2207	Transcriptional regulator
MW696_RS18325	COG1917	Cupin 2, conserved barrel domain protein
MW696_RS18330	COG0697	spore germination
MW696_RS18335	COG2814	Major facilitator Superfamily
MW696_RS18340	COG1309	transcriptional regulator
MW696_RS18345	COG0110	maltose O-acetyltransferase activity
MW696_RS18350	COG2814	Major facilitator Superfamily
MW696_RS18355	COG0789	Transcriptional regulator
MW696_RS18355	COG4978	Transcriptional regulator
MW696_RS18360	COG1114	Component of the transport system for branched-chain amino acids
MW696_RS18365	COG3621	Patatin-like phospholipase
MW696_RS18370	COG1733	regulation of RNA biosynthetic process
MW696_RS18375	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_RS18380	COG1113	amino acid transport
MW696_RS18385	COG1216	Glycosyl transferase, family 2
MW696_RS18395	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MW696_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS18415	COG0778	Nitroreductase
MW696_RS18425	COG0596	Alpha beta hydrolase
MW696_RS18430	COG5566	PFAM Mor transcription activator
MW696_RS18435	COG1595	DNA-templated transcription, initiation
MW696_RS18445	COG2755	lipolytic protein G-D-S-L family
MW696_RS18445	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MW696_RS18450	COG0494	nUDIX hydrolase
MW696_RS18455	COG2814	Major facilitator Superfamily
MW696_RS18460	COG1979	alcohol dehydrogenase
MW696_RS18465	COG0745	RESPONSE REGULATOR receiver
MW696_RS18465	COG2972	Histidine kinase
MW696_RS18475	COG3279	Response regulator of the LytR AlgR family
MW696_RS18480	COG1388	LysM domain
MW696_RS18480	COG4932	domain protein
MW696_RS18485	COG3764	Sortase (surface protein transpeptidase)
MW696_RS18490	COG2851	Citrate transporter
MW696_RS18495	COG3181	Tripartite tricarboxylate transporter family receptor
MW696_RS18500	COG4565	transcriptional regulatory protein
MW696_RS18510	COG2814	Major facilitator Superfamily
MW696_RS18540	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MW696_RS18545	COG0802	atpase or kinase
MW696_RS18550	COG1214	PFAM Peptidase M22, glycoprotease
MW696_RS18555	COG0456	acetyltransferase
MW696_RS18560	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MW696_RS18565	COG0488	(ABC) transporter
MW696_RS18570	COG0315	cyclic pyranopterin monophosphate synthase activity
MW696_RS18575	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MW696_RS18580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MW696_RS18585	COG0805	protein transport
MW696_RS18595	COG1266	CAAX protease self-immunity
MW696_RS18600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MW696_RS18605	COG0459	protein refolding
MW696_RS18630	COG0756	dUTP diphosphatase activity
MW696_RS18670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_RS18685	COG2323	membrane
MW696_RS18690	COG2135	peptidase activity
MW696_RS18695	COG0346	lactoylglutathione lyase activity
MW696_RS18700	COG0531	amino acid
MW696_RS18735	COG3189	MarR family transcriptional regulator
MW696_RS18740	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MW696_RS18745	COG2272	Belongs to the type-B carboxylesterase lipase family
MW696_RS18750	COG2814	Major facilitator Superfamily
MW696_RS18760	COG1378	Sugar-specific transcriptional regulator TrmB
MW696_RS18765	COG1280	lysine exporter protein (LysE YggA)
MW696_RS18770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MW696_RS18800	COG0726	polysaccharide deacetylase
MW696_RS18810	COG1609	Transcriptional regulator
MW696_RS18820	COG2182	Extracellular solute-binding protein
MW696_RS18825	COG1175	transmembrane transport
MW696_RS18830	COG3833	ABC-type maltose transport systems, permease component
MW696_RS18835	COG5521	maltodextrose utilization protein MalA
MW696_RS18840	COG1554	hydrolase, family 65, central catalytic
MW696_RS18845	COG0366	Alpha amylase catalytic
MW696_RS18850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MW696_RS18875	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MW696_RS18880	COG0823	Involved in the tonB-independent uptake of proteins
MW696_RS18900	COG0702	epimerase
MW696_RS18910	COG2132	Multicopper oxidase
MW696_RS18920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MW696_RS18925	COG0714	Associated with various cellular activities
MW696_RS18930	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MW696_RS18935	COG1305	Transglutaminase-like
MW696_RS18940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MW696_RS18940	COG0519	Catalyzes the synthesis of GMP from XMP
MW696_RS18945	COG2252	PERMEase
MW696_RS18960	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
MW696_RS18970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MW696_RS18975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MW696_RS18980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MW696_RS18985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MW696_RS18990	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MW696_RS18995	COG0047	phosphoribosylformylglycinamidine synthase activity
MW696_RS19000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MW696_RS19005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MW696_RS19010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MW696_RS19015	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MW696_RS19020	COG0138	bifunctional purine biosynthesis protein purh
MW696_RS19025	COG0151	Belongs to the GarS family
MW696_RS19045	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MW696_RS19050	COG1470	cell adhesion involved in biofilm formation
MW696_RS19055	COG4496	protein, YerC YecD
MW696_RS19060	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MW696_RS19065	COG0210	DNA helicase
MW696_RS19070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MW696_RS19075	COG4851	CamS sex pheromone cAM373 precursor
MW696_RS19080	COG1285	pathogenesis
MW696_RS19090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MW696_RS19095	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MW696_RS19100	COG0154	amidase activity
MW696_RS19105	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MW696_RS19110	COG4124	Belongs to the glycosyl hydrolase 26 family
MW696_RS19115	COG1063	alcohol dehydrogenase
MW696_RS19120	COG1309	transcriptional regulator
MW696_RS19125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MW696_RS19130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MW696_RS19135	COG1957	nucleoside hydrolase
MW696_RS19140	COG1597	lipid kinase activity
MW696_RS19145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MW696_RS19165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MW696_RS19170	COG3711	transcriptional antiterminator
MW696_RS19175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MW696_RS19180	COG0457	Tetratricopeptide repeat
MW696_RS19185	COG0457	Tetratricopeptide repeat
MW696_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS19215	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
MW696_RS19215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MW696_RS19220	COG3586	endonuclease activity
MW696_RS19225	COG0697	spore germination
MW696_RS19230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS19235	COG0697	spore germination
MW696_RS19240	COG0217	transcriptional regulatory protein
MW696_RS19255	COG0471	metal ion transport
MW696_RS19260	COG0281	malic enzyme
MW696_RS19265	COG0583	DNA-binding transcription factor activity
MW696_RS19270	COG1012	belongs to the aldehyde dehydrogenase family
MW696_RS19275	COG0840	transmembrane signaling receptor activity
MW696_RS19280	COG0109	protoheme IX farnesyltransferase activity
MW696_RS19285	COG1309	transcriptional regulator
MW696_RS19290	COG0471	metal ion transport
MW696_RS19295	COG0488	(ABC) transporter
MW696_RS19300	COG0640	Transcriptional regulator
MW696_RS19305	COG2814	Major facilitator Superfamily
MW696_RS19310	COG1469	GTP cyclohydrolase I activity
MW696_RS19315	COG0523	cobalamin synthesis protein
MW696_RS19320	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MW696_RS19325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MW696_RS19330	COG0156	8-amino-7-oxononanoate synthase activity
MW696_RS19335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MW696_RS19340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MW696_RS19345	COG2124	cytochrome p450
MW696_RS19350	COG0789	Transcriptional regulator
MW696_RS19355	COG2814	Major facilitator Superfamily
MW696_RS19360	COG0488	(ABC) transporter
MW696_RS19365	COG0513	Belongs to the DEAD box helicase family
MW696_RS19380	COG0471	metal ion transport
MW696_RS19390	COG1136	(ABC) transporter
MW696_RS19410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MW696_RS19420	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MW696_RS19425	COG3858	chitin binding
MW696_RS19435	COG5658	integral membrane protein
MW696_RS19440	COG0640	Transcriptional regulator
MW696_RS19445	COG1254	Belongs to the acylphosphatase family
MW696_RS19450	COG2258	MOSC domain
MW696_RS19465	COG0024	Methionine aminopeptidase
MW696_RS19470	COG1368	sulfuric ester hydrolase activity
MW696_RS19480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS19480	COG1263	PTS System
MW696_RS19485	COG0366	Alpha amylase catalytic
MW696_RS19490	COG2188	Transcriptional regulator
MW696_RS19505	COG0463	Glycosyl transferase, family 2
MW696_RS19510	COG0457	Tetratricopeptide repeat
MW696_RS19510	COG0463	Glycosyl transferase, family 2
MW696_RS19515	COG0438	transferase activity, transferring glycosyl groups
MW696_RS19530	COG0673	inositol 2-dehydrogenase activity
MW696_RS19545	COG2076	Multidrug Resistance protein
MW696_RS19550	COG1309	transcriptional regulator
MW696_RS19555	COG0657	acetylesterase activity
MW696_RS19560	COG1733	regulation of RNA biosynthetic process
MW696_RS19565	COG0778	Nitroreductase
MW696_RS19580	COG0737	Belongs to the 5'-nucleotidase family
MW696_RS19585	COG0693	protein deglycase activity
MW696_RS19590	COG4840	Belongs to the UPF0435 family
MW696_RS19595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MW696_RS19600	COG4980	gas vesicle protein
MW696_RS19605	COG1295	ribonuclease BN
MW696_RS19610	COG0477	Major facilitator Superfamily
MW696_RS19620	COG0387	Pfam Sodium calcium exchanger
MW696_RS19630	COG0535	radical SAM domain protein
MW696_RS19640	COG0726	polysaccharide deacetylase
MW696_RS19645	COG0371	Dehydrogenase
MW696_RS19660	COG0598	Magnesium transport protein CorA
MW696_RS19665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MW696_RS19670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MW696_RS19675	COG4637	Psort location Cytoplasmic, score
MW696_RS19695	COG1819	glycosyl
MW696_RS19705	COG0477	Major facilitator Superfamily
MW696_RS19710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS19710	COG1263	PTS System
MW696_RS19715	COG3711	transcriptional antiterminator
MW696_RS19725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MW696_RS19730	COG0022	dehydrogenase e1 component
MW696_RS19735	COG0508	dehydrogenase complex catalyzes the overall conversion of
MW696_RS19740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MW696_RS19745	COG3284	Transcriptional regulator
MW696_RS19750	COG1742	UPF0060 membrane protein
MW696_RS19755	COG1486	melibiose metabolic process
MW696_RS19760	COG1737	Transcriptional regulator
MW696_RS19765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MW696_RS19765	COG1263	PTS System
MW696_RS19775	COG1733	regulation of RNA biosynthetic process
MW696_RS19780	COG2259	Doxx family
MW696_RS19785	COG2514	catechol 2,3-dioxygenase activity
MW696_RS19795	COG3507	Belongs to the glycosyl hydrolase 43 family
MW696_RS19800	COG2207	Transcriptional regulator
MW696_RS19800	COG1917	Cupin 2, conserved barrel domain protein
MW696_RS19805	COG1653	transport
MW696_RS19810	COG1653	transport
MW696_RS19815	COG1309	transcriptional regulator
MW696_RS19820	COG2814	Major facilitator Superfamily
MW696_RS19825	COG2249	NAD(P)H dehydrogenase (quinone) activity
MW696_RS19830	COG1051	belongs to the nudix hydrolase family
MW696_RS19840	COG0392	lysyltransferase activity
MW696_RS19840	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MW696_RS19845	COG0384	phenazine biosynthesis protein PhzF
MW696_RS19850	COG0778	Nitroreductase
MW696_RS19875	COG2137	regulation of response to DNA damage stimulus
MW696_RS19900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MW696_RS19905	COG0463	Glycosyl transferase, family 2
MW696_RS19915	COG4485	Bacterial membrane protein, YfhO
MW696_RS19920	COG1988	membrane-bound metal-dependent
MW696_RS19925	COG1194	a g-specific adenine glycosylase
MW696_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS19950	COG3557	Belongs to the UPF0374 family
MW696_RS19955	COG1132	(ABC) transporter
MW696_RS19960	COG0444	Belongs to the ABC transporter superfamily
MW696_RS19965	COG4608	Belongs to the ABC transporter superfamily
MW696_RS19970	COG0747	negative chemotaxis
MW696_RS19975	COG0601	transmembrane transport
MW696_RS19980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_RS19985	COG4129	membrane
MW696_RS19990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MW696_RS19995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MW696_RS20000	COG0735	belongs to the Fur family
MW696_RS20075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MW696_RS20095	COG0710	3-dehydroquinate dehydratase activity
MW696_RS20100	COG4326	sporulation control protein
MW696_RS20105	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MW696_RS20110	COG1116	anion transmembrane transporter activity
MW696_RS20115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MW696_RS20120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MW696_RS20125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MW696_RS20135	COG1476	TRANSCRIPTIONal
MW696_RS20145	COG1122	ATPase activity
MW696_RS20165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MW696_RS20175	COG3382	B3 4 domain protein
MW696_RS20180	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MW696_RS20190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MW696_RS20195	COG0789	Transcriptional regulator
MW696_RS20200	COG1664	Polymer-forming cytoskeletal
MW696_RS20210	COG2766	serine protein kinase
MW696_RS20215	COG2718	Belongs to the UPF0229 family
MW696_RS20220	COG1566	PFAM secretion protein HlyD family protein
MW696_RS20225	COG2814	Major facilitator Superfamily
MW696_RS20230	COG0655	NAD(P)H dehydrogenase (quinone) activity
MW696_RS20245	COG1725	Transcriptional regulator
MW696_RS20250	COG1131	(ABC) transporter
MW696_RS20255	COG1131	(ABC) transporter
MW696_RS20260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MW696_RS20265	COG1278	Cold shock
MW696_RS20270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MW696_RS20275	COG2011	ABC-type metal ion transport system permease component
MW696_RS20280	COG1464	Belongs to the NlpA lipoprotein family
MW696_RS20285	COG1823	symporter activity
MW696_RS20310	COG5577	PFAM Coat F domain
MW696_RS20315	COG5002	protein histidine kinase activity
MW696_RS20320	COG4085	toxin activity
MW696_RS20320	COG0737	Belongs to the 5'-nucleotidase family
MW696_RS20320	COG1525	nuclease
MW696_RS20325	COG3764	Sortase (surface protein transpeptidase)
MW696_RS20330	COG0517	IMP dehydrogenase activity
MW696_RS20330	COG1125	glycine betaine transport
MW696_RS20335	COG1174	glycine betaine transport
MW696_RS20340	COG1732	Glycine betaine
MW696_RS20345	COG1174	glycine betaine transport
MW696_RS20350	COG0564	pseudouridine synthase activity
MW696_RS20360	COG0517	IMP dehydrogenase activity
MW696_RS20365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MW696_RS20370	COG3153	acetyltransferase
MW696_RS20370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MW696_RS20375	COG0488	(ABC) transporter
MW696_RS20390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MW696_RS20395	COG0604	alcohol dehydrogenase
MW696_RS20400	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MW696_RS20405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MW696_RS20410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MW696_RS20415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MW696_RS20420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MW696_RS20445	COG4585	Histidine kinase
MW696_RS20445	COG2203	Gaf domain
MW696_RS20450	COG2197	response regulator
MW696_RS20455	COG0431	NADPH-dependent FMN reductase
MW696_RS20470	COG1959	2 iron, 2 sulfur cluster binding
MW696_RS20475	COG1017	nitric oxide dioxygenase activity
MW696_RS20475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MW696_RS20480	COG2719	SpoVR family
MW696_RS20485	COG1785	Belongs to the alkaline phosphatase family
MW696_RS20495	COG1388	LysM domain
MW696_RS20495	COG0791	NLP P60 protein
MW696_RS20500	COG0583	DNA-binding transcription factor activity
MW696_RS20505	COG0372	Belongs to the citrate synthase family
MW696_RS20510	COG1846	Transcriptional regulator
MW696_RS20515	COG0531	amino acid
MW696_RS20520	COG0733	neurotransmitter:sodium symporter activity
MW696_RS20530	COG3708	Transcriptional regulator
MW696_RS20530	COG2207	Transcriptional regulator
MW696_RS20535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS20555	COG1595	DNA-templated transcription, initiation
MW696_RS20560	COG0204	Acyl-transferase
MW696_RS20575	COG1253	flavin adenine dinucleotide binding
MW696_RS20580	COG0789	Transcriptional regulator
MW696_RS20585	COG1253	flavin adenine dinucleotide binding
MW696_RS20605	COG3739	integral membrane protein
MW696_RS20610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MW696_RS20615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MW696_RS20620	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_RS20630	COG0668	transmembrane transport
MW696_RS20635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MW696_RS20640	COG0454	-acetyltransferase
MW696_RS20645	COG0726	polysaccharide deacetylase
MW696_RS20655	COG1757	Na H antiporter
MW696_RS20660	COG2017	converts alpha-aldose to the beta-anomer
MW696_RS20685	COG0589	response to stress
MW696_RS20690	COG1132	(ABC) transporter
MW696_RS20695	COG1132	(ABC) transporter
MW696_RS20700	COG0702	epimerase
MW696_RS20725	COG3842	ATPase activity
MW696_RS20730	COG2508	Transcriptional regulator
MW696_RS20740	COG0189	ligase activity
MW696_RS20745	COG0189	ligase activity
MW696_RS20750	COG4399	Belongs to the UPF0754 family
MW696_RS20755	COG3679	Belongs to the UPF0342 family
MW696_RS20760	COG0561	phosphatase activity
MW696_RS20775	COG0475	glutathione-regulated potassium exporter activity
MW696_RS20780	COG0490	domain, Protein
MW696_RS20790	COG1024	Enoyl-CoA hydratase
MW696_RS20795	COG0457	Tetratricopeptide repeat
MW696_RS20810	COG4152	abc transporter atp-binding protein
MW696_RS20815	COG1668	transmembrane transport
MW696_RS20820	COG0420	3'-5' exonuclease activity
MW696_RS20825	COG4717	serine-type aminopeptidase activity
MW696_RS20830	COG3481	metal-dependent phosphohydrolase, HD sub domain
MW696_RS20840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MW696_RS20870	COG1846	Transcriptional regulator
MW696_RS20875	COG4980	gas vesicle protein
MW696_RS20890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MW696_RS20895	COG0537	adenosine 5'-monophosphoramidase activity
MW696_RS20900	COG1131	(ABC) transporter
MW696_RS20905	COG4473	ABC transporter
MW696_RS20915	COG1473	amidohydrolase
MW696_RS20925	COG2329	Antibiotic biosynthesis monooxygenase
MW696_RS20930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MW696_RS20935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MW696_RS20940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MW696_RS20945	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MW696_RS20950	COG1309	transcriptional regulator
MW696_RS20955	COG1511	domain protein
MW696_RS20960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_RS20965	COG1363	Peptidase, m42
MW696_RS20975	COG1301	dicarboxylic acid transport
MW696_RS20985	COG1234	tRNA 3'-trailer cleavage
MW696_RS20990	COG0095	Lipoate-protein ligase
MW696_RS20995	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_RS21005	COG1396	sequence-specific DNA binding
MW696_RS21020	COG0501	Belongs to the peptidase M48B family
MW696_RS21030	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MW696_RS21035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS21040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MW696_RS21045	COG0406	alpha-ribazole phosphatase activity
MW696_RS21050	COG0840	transmembrane signaling receptor activity
MW696_RS21055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MW696_RS21055	COG0723	plastoquinol--plastocyanin reductase activity
MW696_RS21060	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS21070	COG4903	ComK protein
MW696_RS21080	COG0398	Pfam SNARE associated Golgi protein
MW696_RS21085	COG0681	Belongs to the peptidase S26 family
MW696_RS21105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MW696_RS21115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MW696_RS21120	COG3257	ureidoglycine aminohydrolase activity
MW696_RS21125	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MW696_RS21130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MW696_RS21135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MW696_RS21140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MW696_RS21150	COG0549	Belongs to the carbamate kinase family
MW696_RS21160	COG0457	Tetratricopeptide repeat
MW696_RS21170	COG3180	Ammonia monooxygenase
MW696_RS21185	COG3546	catalase activity
MW696_RS21190	COG0318	PFAM AMP-dependent synthetase and ligase
MW696_RS21195	COG2720	vancomycin resistance protein
MW696_RS21200	COG5002	protein histidine kinase activity
MW696_RS21205	COG0745	RESPONSE REGULATOR receiver
MW696_RS21210	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MW696_RS21215	COG0725	ABC transporter, periplasmic molybdate-binding protein
MW696_RS21220	COG4149	molybdate abc transporter
MW696_RS21225	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MW696_RS21230	COG1074	ATP-dependent DNA helicase activity
MW696_RS21235	COG0420	3'-5' exonuclease activity
MW696_RS21240	COG0419	ATPase involved in DNA repair
MW696_RS21285	COG5337	Spore coat protein CotH
MW696_RS21295	COG0179	Fumarylacetoacetate (FAA) hydrolase
MW696_RS21315	COG0367	asparagine synthase
MW696_RS21320	COG0534	Mate efflux family protein
MW696_RS21325	COG1917	Cupin 2, conserved barrel domain protein
MW696_RS21325	COG2207	Transcriptional regulator
MW696_RS21355	COG0697	spore germination
MW696_RS21360	COG1279	arginine transmembrane transporter activity
MW696_RS21365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MW696_RS21375	COG0076	glutamate decarboxylase activity
MW696_RS21400	COG2153	protein acetylation
MW696_RS21405	COG0646	methionine synthase
MW696_RS21405	COG1410	methionine synthase
MW696_RS21410	COG0646	methionine synthase
MW696_RS21410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MW696_RS21415	COG1666	GTP binding
MW696_RS21420	COG2996	Protein conserved in bacteria
MW696_RS21435	COG1307	EDD domain protein, DegV family
MW696_RS21440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MW696_RS21450	COG0516	GMP reductase activity
MW696_RS21465	COG0561	phosphatase activity
MW696_RS21470	COG1073	alpha beta
MW696_RS21475	COG2151	metal-sulfur cluster biosynthetic enzyme
MW696_RS21480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MW696_RS21485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MW696_RS21490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MW696_RS21495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MW696_RS21500	COG0505	Belongs to the CarA family
MW696_RS21505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MW696_RS21510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MW696_RS21525	COG2267	carboxylic ester hydrolase activity
MW696_RS21535	COG1744	ABC transporter substrate-binding protein PnrA-like
MW696_RS21550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MW696_RS21555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MW696_RS21560	COG5504	Zn-dependent protease
MW696_RS21565	COG0444	Belongs to the ABC transporter superfamily
MW696_RS21570	COG4608	Belongs to the ABC transporter superfamily
MW696_RS21580	COG0601	transmembrane transport
MW696_RS21585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_RS21595	COG0180	Tryptophanyl-tRNA synthetase
MW696_RS21600	COG4166	transmembrane transport
MW696_RS21605	COG0601	transmembrane transport
MW696_RS21610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MW696_RS21615	COG0444	Belongs to the ABC transporter superfamily
MW696_RS21620	COG4608	Belongs to the ABC transporter superfamily
MW696_RS21625	COG0456	acetyltransferase
MW696_RS21630	COG1393	Belongs to the ArsC family
MW696_RS21635	COG0861	Integral membrane protein TerC family
MW696_RS21645	COG4862	establishment of competence for transformation
MW696_RS21650	COG4469	Competence protein
MW696_RS21655	COG1164	Oligoendopeptidase f
MW696_RS21665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MW696_RS21670	COG2346	COG2346, Truncated hemoglobins
MW696_RS21675	COG0741	lytic transglycosylase activity
MW696_RS21680	COG4116	CYTH
MW696_RS21690	COG2357	RelA SpoT domain protein
MW696_RS21695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MW696_RS21700	COG0564	pseudouridine synthase activity
MW696_RS21705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MW696_RS21710	COG0475	glutathione-regulated potassium exporter activity
MW696_RS21710	COG0569	domain protein
MW696_RS21715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MW696_RS21720	COG0352	thiamine-phosphate diphosphorylase activity
MW696_RS21730	COG2104	thiamine diphosphate biosynthetic process
MW696_RS21735	COG2022	thiamine diphosphate biosynthetic process
MW696_RS21740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MW696_RS21745	COG0351	phosphomethylpyrimidine kinase
MW696_RS21750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MW696_RS21805	COG0210	DNA helicase
MW696_RS21815	COG0586	Pfam SNARE associated Golgi protein
MW696_RS21820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MW696_RS21830	COG2246	polysaccharide biosynthetic process
MW696_RS21835	COG2153	protein acetylation
MW696_RS21840	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MW696_RS21845	COG2382	esterase
MW696_RS21850	COG0626	cystathionine gamma-synthase activity
MW696_RS21855	COG0626	cystathionine gamma-synthase activity
MW696_RS21880	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MW696_RS21890	COG3591	Belongs to the peptidase S1B family
MW696_RS21915	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS21920	COG0346	lactoylglutathione lyase activity
MW696_RS21940	COG2267	carboxylic ester hydrolase activity
MW696_RS21960	COG0531	amino acid
MW696_RS21970	COG0583	DNA-binding transcription factor activity
MW696_RS21975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MW696_RS21980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MW696_RS21985	COG0583	DNA-binding transcription factor activity
MW696_RS21990	COG0697	spore germination
MW696_RS21995	COG0346	lactoylglutathione lyase activity
MW696_RS22005	COG3584	3D domain protein
MW696_RS22005	COG1388	LysM domain
MW696_RS22015	COG5434	Belongs to the glycosyl hydrolase 28 family
MW696_RS22020	COG2814	Major facilitator Superfamily
MW696_RS22025	COG1309	transcriptional regulator
MW696_RS22060	COG5444	nuclease activity
MW696_RS22065	COG0457	Tetratricopeptide repeat
MW696_RS22090	COG5444	nuclease activity
MW696_RS22105	COG4195	phage-related replication protein
MW696_RS22110	COG2856	Zn peptidase
MW696_RS22115	COG1396	sequence-specific DNA binding
MW696_RS22130	COG1522	sequence-specific DNA binding
MW696_RS22135	COG1484	DNA-dependent DNA replication
MW696_RS22155	COG1595	DNA-templated transcription, initiation
MW696_RS22165	COG0584	glycerophosphoryl diester phosphodiesterase
MW696_RS22185	COG1802	Transcriptional regulator
MW696_RS22190	COG1063	alcohol dehydrogenase
MW696_RS22195	COG1312	Catalyzes the dehydration of D-mannonate
MW696_RS22200	COG1028	Short-chain dehydrogenase reductase Sdr
MW696_RS22205	COG1063	alcohol dehydrogenase
MW696_RS22210	COG2271	Major facilitator Superfamily