locus-tag	class	description
FED51_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FED51_RS00010	COG0592	DNA-directed DNA polymerase activity
FED51_RS00015	COG2501	S4 domain
FED51_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FED51_RS00030	COG0187	DNA topoisomerase II activity
FED51_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FED51_RS00125	COG0516	GMP reductase activity
FED51_RS00125	COG0517	IMP dehydrogenase activity
FED51_RS00135	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FED51_RS00140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FED51_RS00145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FED51_RS00155	COG0737	Belongs to the 5'-nucleotidase family
FED51_RS00165	COG4608	Belongs to the ABC transporter superfamily
FED51_RS00170	COG0444	Belongs to the ABC transporter superfamily
FED51_RS00175	COG0601	transmembrane transport
FED51_RS00180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FED51_RS00185	COG0747	negative chemotaxis
FED51_RS00195	COG0590	tRNA wobble adenosine to inosine editing
FED51_RS00210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FED51_RS00215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FED51_RS00220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FED51_RS00255	COG3344	reverse transcriptase
FED51_RS00265	COG1982	Orn Lys Arg decarboxylase major
FED51_RS00270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FED51_RS00275	COG3870	Protein conserved in bacteria
FED51_RS00280	COG0470	DNA polymerase III
FED51_RS00285	COG1774	PSP1 C-terminal conserved region
FED51_RS00290	COG4467	Involved in initiation control of chromosome replication
FED51_RS00295	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FED51_RS00300	COG2827	Endonuclease containing a URI domain
FED51_RS00305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FED51_RS00310	COG2002	toxin-antitoxin pair type II binding
FED51_RS00325	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FED51_RS00325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FED51_RS00330	COG0084	hydrolase, TatD family'
FED51_RS00335	COG3584	3D domain protein
FED51_RS00335	COG3583	domain protein
FED51_RS00345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FED51_RS00355	COG4466	Protein conserved in bacteria
FED51_RS00365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FED51_RS00370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FED51_RS00375	COG0251	oxidation-reduction process
FED51_RS00380	COG2088	sporulation resulting in formation of a cellular spore
FED51_RS00385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FED51_RS00390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FED51_RS00395	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FED51_RS00400	COG0193	aminoacyl-tRNA hydrolase activity
FED51_RS00410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FED51_RS00415	COG2002	toxin-antitoxin pair type II binding
FED51_RS00420	COG2244	polysaccharide biosynthetic process
FED51_RS00425	COG3956	TIGRFAM MazG family protein
FED51_RS00430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FED51_RS00450	COG1098	S1 RNA binding domain
FED51_RS00460	COG2208	phosphoserine phosphatase activity
FED51_RS00465	COG2304	oxidoreductase activity
FED51_RS00470	COG0515	serine threonine protein kinase
FED51_RS00475	COG2966	Psort location CytoplasmicMembrane, score
FED51_RS00485	COG0037	tRNA processing
FED51_RS00490	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FED51_RS00495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FED51_RS00500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FED51_RS00505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FED51_RS00510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FED51_RS00515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FED51_RS00520	COG0512	Glutamine amidotransferase of anthranilate synthase
FED51_RS00525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FED51_RS00530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FED51_RS00535	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FED51_RS00540	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FED51_RS00545	COG1396	sequence-specific DNA binding
FED51_RS00550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FED51_RS00555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FED51_RS00565	COG3344	reverse transcriptase
FED51_RS00660	COG3344	reverse transcriptase
FED51_RS00675	COG3880	PFAM UvrB UvrC protein
FED51_RS00680	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FED51_RS00685	COG0542	response to heat
FED51_RS00690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FED51_RS00695	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FED51_RS00700	COG4956	integral membrane protein (PIN domain superfamily)
FED51_RS00705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FED51_RS00710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FED51_RS00715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FED51_RS00720	COG1045	serine acetyltransferase
FED51_RS00725	COG0215	cysteine-tRNA ligase activity
FED51_RS00735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FED51_RS00740	COG3688	RNA-binding protein containing a PIN domain
FED51_RS00750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FED51_RS00755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FED51_RS00760	COG0250	Participates in transcription elongation, termination and antitermination
FED51_RS00765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FED51_RS00770	COG0081	regulation of translation
FED51_RS00775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FED51_RS00780	COG0222	ribosome binding
FED51_RS00785	COG2813	Specifically methylates the guanine in position
FED51_RS00790	COG0085	RNA polymerase activity
FED51_RS00795	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FED51_RS00800	COG1358	cellular component organization or biogenesis
FED51_RS00805	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FED51_RS00810	COG0049	tRNA binding
FED51_RS00815	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FED51_RS00820	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FED51_RS00825	COG0051	transcription antitermination factor activity, RNA binding
FED51_RS00830	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FED51_RS00835	COG0088	Forms part of the polypeptide exit tunnel
FED51_RS00840	COG0089	rRNA binding
FED51_RS00845	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FED51_RS00850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FED51_RS00855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FED51_RS00860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FED51_RS00865	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FED51_RS00870	COG0255	Belongs to the universal ribosomal protein uL29 family
FED51_RS00875	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FED51_RS00880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FED51_RS00885	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FED51_RS00890	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FED51_RS00895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FED51_RS00900	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FED51_RS00905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FED51_RS00910	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FED51_RS00915	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FED51_RS00920	COG1841	ribosomal large subunit assembly
FED51_RS00925	COG0200	Binds to the 23S rRNA
FED51_RS00930	COG0201	protein transport
FED51_RS00935	COG0563	adenylate kinase activity
FED51_RS00940	COG0024	Methionine aminopeptidase
FED51_RS00950	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FED51_RS00955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FED51_RS00960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FED51_RS00965	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FED51_RS00970	COG0202	RNA polymerase activity
FED51_RS00975	COG0203	ribosomal protein L17
FED51_RS00980	COG1122	ATPase activity
FED51_RS00985	COG1122	ATPase activity
FED51_RS00990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FED51_RS00995	COG0101	tRNA pseudouridine synthase activity
FED51_RS01000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FED51_RS01005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FED51_RS01055	COG1653	transport
FED51_RS01060	COG1175	transmembrane transport
FED51_RS01065	COG0395	ABC-type sugar transport system, permease component
FED51_RS01070	COG5578	integral membrane protein
FED51_RS01080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FED51_RS01085	COG0765	amino acid transport
FED51_RS01090	COG1126	abc transporter atp-binding protein
FED51_RS01125	COG2723	6-phospho-beta-galactosidase activity
FED51_RS01130	COG1486	melibiose metabolic process
FED51_RS01150	COG3327	negative regulation of DNA-templated transcription, initiation
FED51_RS01160	COG3396	Phenylacetate-CoA oxygenase
FED51_RS01175	COG2151	metal-sulfur cluster biosynthetic enzyme
FED51_RS01185	COG1024	Enoyl-CoA hydratase
FED51_RS01190	COG1024	Enoyl-CoA hydratase
FED51_RS01195	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS01200	COG1250	3-hydroxyacyl-CoA dehydrogenase
FED51_RS01205	COG0183	Belongs to the thiolase family
FED51_RS01215	COG1024	Enoyl-CoA hydratase
FED51_RS01220	COG0659	secondary active sulfate transmembrane transporter activity
FED51_RS01240	COG1522	sequence-specific DNA binding
FED51_RS01265	COG0733	neurotransmitter:sodium symporter activity
FED51_RS01275	COG1620	l-lactate permease
FED51_RS01280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FED51_RS01305	COG3344	reverse transcriptase
FED51_RS01325	COG4821	SIS domain
FED51_RS01330	COG2181	nitrate reductase activity
FED51_RS01335	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FED51_RS01340	COG1140	nitrate reductase beta subunit
FED51_RS01345	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FED51_RS01350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FED51_RS01360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FED51_RS01365	COG2223	nitrite transmembrane transporter activity
FED51_RS01400	COG2814	Major facilitator Superfamily
FED51_RS01410	COG0860	N-Acetylmuramoyl-L-alanine amidase
FED51_RS01415	COG0489	protein tyrosine kinase activity
FED51_RS01425	COG2194	sulfuric ester hydrolase activity
FED51_RS01430	COG0726	polysaccharide deacetylase
FED51_RS01495	COG0831	urea catabolic process
FED51_RS01500	COG0832	Belongs to the urease beta subunit family
FED51_RS01505	COG0804	urea catabolic process
FED51_RS01510	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FED51_RS01520	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FED51_RS01525	COG0829	nickel cation binding
FED51_RS01530	COG0803	Belongs to the bacterial solute-binding protein 9 family
FED51_RS01595	COG1595	DNA-templated transcription, initiation
FED51_RS01600	COG5662	AntiSigma factor
FED51_RS01605	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FED51_RS01615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FED51_RS01620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FED51_RS01630	COG0745	RESPONSE REGULATOR receiver
FED51_RS01635	COG2205	protein histidine kinase activity
FED51_RS01640	COG1136	(ABC) transporter
FED51_RS01645	COG0577	efflux transmembrane transporter activity
FED51_RS01675	COG0346	lactoylglutathione lyase activity
FED51_RS01680	COG0384	phenazine biosynthesis protein PhzF
FED51_RS01685	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FED51_RS01690	COG1136	(ABC) transporter
FED51_RS01695	COG0577	efflux transmembrane transporter activity
FED51_RS01700	COG0745	RESPONSE REGULATOR receiver
FED51_RS01705	COG2205	protein histidine kinase activity
FED51_RS01715	COG1131	(ABC) transporter
FED51_RS01720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FED51_RS01750	COG2190	(PTS) system
FED51_RS01750	COG1263	PTS System
FED51_RS01750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS01755	COG3711	transcriptional antiterminator
FED51_RS01785	COG1959	2 iron, 2 sulfur cluster binding
FED51_RS01885	COG0515	serine threonine protein kinase
FED51_RS01885	COG2815	serine threonine protein kinase
FED51_RS01955	COG1518	maintenance of DNA repeat elements
FED51_RS01960	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FED51_RS01990	COG0601	transmembrane transport
FED51_RS01995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FED51_RS02000	COG0444	Belongs to the ABC transporter superfamily
FED51_RS02005	COG4608	Belongs to the ABC transporter superfamily
FED51_RS02075	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FED51_RS02080	COG1309	transcriptional regulator
FED51_RS02100	COG2031	fatty acid transporter
FED51_RS02130	COG0523	cobalamin synthesis protein
FED51_RS02140	COG0717	Belongs to the dCTP deaminase family
FED51_RS02145	COG0822	iron-sulfur transferase activity
FED51_RS02160	COG1193	negative regulation of DNA recombination
FED51_RS02185	COG3173	Aminoglycoside phosphotransferase
FED51_RS02190	COG1131	(ABC) transporter
FED51_RS02195	COG1725	Transcriptional regulator
FED51_RS02225	COG0697	spore germination
FED51_RS02230	COG0640	Transcriptional regulator
FED51_RS02235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FED51_RS02245	COG2169	Transcriptional regulator
FED51_RS02255	COG3290	protein histidine kinase activity
FED51_RS02260	COG4565	transcriptional regulatory protein
FED51_RS02265	COG0281	malic enzyme
FED51_RS02295	COG0778	Nitroreductase
FED51_RS02315	COG0789	Transcriptional regulator
FED51_RS02320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FED51_RS02325	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS02340	COG0366	Alpha amylase catalytic
FED51_RS02345	COG0659	secondary active sulfate transmembrane transporter activity
FED51_RS02360	COG2226	methyltransferase
FED51_RS02365	COG2188	Transcriptional regulator
FED51_RS02375	COG0363	glucosamine-6-phosphate deaminase activity
FED51_RS02380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FED51_RS02385	COG1263	PTS System
FED51_RS02385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS02390	COG1522	sequence-specific DNA binding
FED51_RS02400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FED51_RS02405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FED51_RS02405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FED51_RS02410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FED51_RS02410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FED51_RS02420	COG1609	Transcriptional regulator
FED51_RS02430	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS02440	COG0028	Belongs to the TPP enzyme family
FED51_RS02455	COG0710	3-dehydroquinate dehydratase activity
FED51_RS02460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FED51_RS02465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FED51_RS02470	COG0840	transmembrane signaling receptor activity
FED51_RS02470	COG3290	protein histidine kinase activity
FED51_RS02485	COG1309	transcriptional regulator
FED51_RS02490	COG1280	lysine exporter protein (LysE YggA)
FED51_RS02500	COG1279	arginine transmembrane transporter activity
FED51_RS02505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FED51_RS02520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FED51_RS02530	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FED51_RS02535	COG3639	organic phosphonate transmembrane transporter activity
FED51_RS02540	COG3639	organic phosphonate transmembrane transporter activity
FED51_RS02545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FED51_RS02630	COG0628	permease
FED51_RS02635	COG1968	undecaprenyl-diphosphatase activity
FED51_RS02650	COG0569	domain protein
FED51_RS02660	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FED51_RS02665	COG3639	organic phosphonate transmembrane transporter activity
FED51_RS02670	COG3639	organic phosphonate transmembrane transporter activity
FED51_RS02715	COG0395	ABC-type sugar transport system, permease component
FED51_RS02720	COG1653	transport
FED51_RS02725	COG2207	Transcriptional regulator
FED51_RS02730	COG4209	transmembrane transport
FED51_RS02735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FED51_RS02740	COG1653	transport
FED51_RS02745	COG0673	inositol 2-dehydrogenase activity
FED51_RS02750	COG5578	integral membrane protein
FED51_RS02755	COG0385	Bile acid
FED51_RS02760	COG2721	sulfolactate sulfo-lyase activity
FED51_RS02770	COG0246	Mannitol dehydrogenase
FED51_RS02795	COG0561	phosphatase activity
FED51_RS02810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FED51_RS02815	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FED51_RS02820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FED51_RS02835	COG0840	transmembrane signaling receptor activity
FED51_RS02850	COG1733	regulation of RNA biosynthetic process
FED51_RS02860	COG2239	Acts as a magnesium transporter
FED51_RS02865	COG3842	ATPase activity
FED51_RS02875	COG1178	ABC-type Fe3 transport system permease component
FED51_RS02885	COG0803	Belongs to the bacterial solute-binding protein 9 family
FED51_RS02890	COG0705	Rhomboid family
FED51_RS02895	COG0736	holo-[acyl-carrier-protein] synthase activity
FED51_RS02900	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FED51_RS02905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FED51_RS02910	COG0864	Transcriptional regulator
FED51_RS02915	COG2337	Toxic component of a toxin-antitoxin (TA) module
FED51_RS02920	COG1366	Belongs to the anti-sigma-factor antagonist family
FED51_RS02925	COG1366	Belongs to the anti-sigma-factor antagonist family
FED51_RS02930	COG2172	sigma factor antagonist activity
FED51_RS02935	COG2208	phosphoserine phosphatase activity
FED51_RS02940	COG1366	Belongs to the anti-sigma-factor antagonist family
FED51_RS02945	COG2172	sigma factor antagonist activity
FED51_RS02950	COG1191	sigma factor activity
FED51_RS02960	COG2183	response to ionizing radiation
FED51_RS02970	COG3091	SprT-like family
FED51_RS03050	COG3852	Histidine kinase
FED51_RS03055	COG2204	response regulator
FED51_RS03065	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS03070	COG1285	pathogenesis
FED51_RS03075	COG0626	cystathionine gamma-synthase activity
FED51_RS03095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FED51_RS03100	COG0802	atpase or kinase
FED51_RS03105	COG1214	PFAM Peptidase M22, glycoprotease
FED51_RS03110	COG0456	acetyltransferase
FED51_RS03115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FED51_RS03125	COG0488	(ABC) transporter
FED51_RS03130	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FED51_RS03135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FED51_RS03140	COG0805	protein transport
FED51_RS03145	COG2814	Major facilitator Superfamily
FED51_RS03150	COG1929	Belongs to the glycerate kinase type-1 family
FED51_RS03155	COG2608	mercury ion transmembrane transporter activity
FED51_RS03160	COG2217	Heavy metal translocating P-type atpase
FED51_RS03165	COG1937	Protein conserved in bacteria
FED51_RS03175	COG1266	CAAX protease self-immunity
FED51_RS03180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FED51_RS03185	COG0459	protein refolding
FED51_RS03210	COG0747	negative chemotaxis
FED51_RS03215	COG0601	transmembrane transport
FED51_RS03220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FED51_RS03225	COG4172	Belongs to the ABC transporter superfamily
FED51_RS03230	COG4608	Belongs to the ABC transporter superfamily
FED51_RS03245	COG1695	Transcriptional regulator
FED51_RS03255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FED51_RS03260	COG2124	cytochrome p450
FED51_RS03265	COG1309	transcriptional regulator
FED51_RS03270	COG2197	response regulator
FED51_RS03275	COG4585	Histidine kinase
FED51_RS03285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FED51_RS03290	COG2188	Transcriptional regulator
FED51_RS03310	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FED51_RS03315	COG0626	cystathionine gamma-synthase activity
FED51_RS03320	COG3457	Alanine racemase
FED51_RS03325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FED51_RS03330	COG3708	Transcriptional regulator
FED51_RS03330	COG2207	Transcriptional regulator
FED51_RS03335	COG2190	(PTS) system
FED51_RS03335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS03335	COG1263	PTS System
FED51_RS03340	COG2723	6-phospho-beta-galactosidase activity
FED51_RS03345	COG0569	domain protein
FED51_RS03350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FED51_RS03355	COG1136	(ABC) transporter
FED51_RS03380	COG0714	Associated with various cellular activities
FED51_RS03385	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FED51_RS03390	COG1305	Transglutaminase-like
FED51_RS03395	COG0519	Catalyzes the synthesis of GMP from XMP
FED51_RS03395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FED51_RS03400	COG2252	PERMEase
FED51_RS03405	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FED51_RS03410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FED51_RS03450	COG2223	nitrite transmembrane transporter activity
FED51_RS03455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FED51_RS03460	COG2146	nitrite reductase [NAD(P)H] activity
FED51_RS03465	COG0243	molybdopterin cofactor binding
FED51_RS03470	COG2258	MOSC domain
FED51_RS03475	COG3424	synthase
FED51_RS03480	COG1755	Isoprenylcysteine carboxyl methyltransferase
FED51_RS03485	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FED51_RS03495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FED51_RS03500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FED51_RS03505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FED51_RS03510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FED51_RS03515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FED51_RS03520	COG0047	phosphoribosylformylglycinamidine synthase activity
FED51_RS03525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FED51_RS03530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FED51_RS03535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FED51_RS03540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FED51_RS03545	COG0138	bifunctional purine biosynthesis protein purh
FED51_RS03550	COG0151	Belongs to the GarS family
FED51_RS03560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FED51_RS03565	COG1470	cell adhesion involved in biofilm formation
FED51_RS03570	COG4496	protein, YerC YecD
FED51_RS03575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FED51_RS03590	COG0393	Putative heavy-metal-binding
FED51_RS03605	COG1078	dGTPase activity
FED51_RS03610	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FED51_RS03615	COG0210	DNA helicase
FED51_RS03620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FED51_RS03625	COG4851	CamS sex pheromone cAM373 precursor
FED51_RS03645	COG1733	regulation of RNA biosynthetic process
FED51_RS03655	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS03660	COG2226	methyltransferase
FED51_RS03670	COG0457	Tetratricopeptide repeat
FED51_RS03675	COG0038	chloride channel
FED51_RS03680	COG2323	membrane
FED51_RS03685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FED51_RS03690	COG0154	amidase activity
FED51_RS03695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FED51_RS03705	COG3708	Transcriptional regulator
FED51_RS03720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS03720	COG1263	PTS System
FED51_RS03725	COG3876	Protein conserved in bacteria
FED51_RS03730	COG1472	Belongs to the glycosyl hydrolase 3 family
FED51_RS03735	COG1597	lipid kinase activity
FED51_RS03760	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS03765	COG0095	Lipoate-protein ligase
FED51_RS03770	COG1404	Belongs to the peptidase S8 family
FED51_RS03775	COG2076	Multidrug Resistance protein
FED51_RS03780	COG2076	Multidrug Resistance protein
FED51_RS03785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FED51_RS03800	COG3942	CHAP domain
FED51_RS03800	COG1388	LysM domain
FED51_RS03805	COG1054	Belongs to the UPF0176 family
FED51_RS03810	COG1937	Protein conserved in bacteria
FED51_RS03820	COG2210	Belongs to the sulfur carrier protein TusA family
FED51_RS03830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FED51_RS03830	COG0425	Belongs to the sulfur carrier protein TusA family
FED51_RS03840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FED51_RS03840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FED51_RS03845	COG0425	Belongs to the sulfur carrier protein TusA family
FED51_RS03850	COG0730	response to heat
FED51_RS03855	COG0640	Transcriptional regulator
FED51_RS03865	COG1404	Belongs to the peptidase S8 family
FED51_RS03870	COG3340	Belongs to the peptidase S51 family
FED51_RS03895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FED51_RS03910	COG1904	glucuronate isomerase
FED51_RS03915	COG1312	Catalyzes the dehydration of D-mannonate
FED51_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS03925	COG0673	inositol 2-dehydrogenase activity
FED51_RS03945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FED51_RS03950	COG1132	(ABC) transporter
FED51_RS03980	COG2409	Drug exporters of the RND superfamily
FED51_RS04005	COG1917	Cupin 2, conserved barrel domain protein
FED51_RS04005	COG2207	Transcriptional regulator
FED51_RS04010	COG0697	spore germination
FED51_RS04040	COG0714	Associated with various cellular activities
FED51_RS04070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FED51_RS04085	COG5577	PFAM Coat F domain
FED51_RS04090	COG2217	Heavy metal translocating P-type atpase
FED51_RS04095	COG2851	Citrate transporter
FED51_RS04100	COG0402	S-adenosylhomocysteine deaminase activity
FED51_RS04110	COG0577	efflux transmembrane transporter activity
FED51_RS04115	COG1136	(ABC) transporter
FED51_RS04120	COG5002	protein histidine kinase activity
FED51_RS04125	COG0745	RESPONSE REGULATOR receiver
FED51_RS04130	COG2311	Membrane
FED51_RS04135	COG2508	Transcriptional regulator
FED51_RS04140	COG2508	Transcriptional regulator
FED51_RS04150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FED51_RS04160	COG3730	PTS system glucitol sorbitol-specific
FED51_RS04165	COG3732	PTS system glucitol sorbitol-specific
FED51_RS04185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FED51_RS04190	COG0022	dehydrogenase e1 component
FED51_RS04195	COG0508	dehydrogenase complex catalyzes the overall conversion of
FED51_RS04200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FED51_RS04210	COG3711	transcriptional antiterminator
FED51_RS04215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FED51_RS04220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FED51_RS04225	COG4585	Histidine kinase
FED51_RS04235	COG1940	carbohydrate kinase activity
FED51_RS04240	COG5578	integral membrane protein
FED51_RS04245	COG0383	alpha-mannosidase activity
FED51_RS04260	COG3275	phosphorelay sensor kinase activity
FED51_RS04265	COG4753	response regulator
FED51_RS04265	COG2207	Transcriptional regulator
FED51_RS04270	COG4209	transmembrane transport
FED51_RS04275	COG0395	ABC-type sugar transport system, permease component
FED51_RS04280	COG1653	transport
FED51_RS04285	COG1940	carbohydrate kinase activity
FED51_RS04290	COG1607	acyl-coa hydrolase
FED51_RS04300	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS04310	COG3395	kinase activity
FED51_RS04315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FED51_RS04320	COG2610	gluconate transmembrane transporter activity
FED51_RS04345	COG1376	ErfK ybiS ycfS ynhG family protein
FED51_RS04365	COG1131	(ABC) transporter
FED51_RS04370	COG2205	protein histidine kinase activity
FED51_RS04375	COG0745	RESPONSE REGULATOR receiver
FED51_RS04380	COG4106	trans-aconitate 2-methyltransferase activity
FED51_RS04385	COG2244	polysaccharide biosynthetic process
FED51_RS04390	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FED51_RS04395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FED51_RS04400	COG1349	DNA-binding transcription factor activity
FED51_RS04405	COG1105	Belongs to the carbohydrate kinase PfkB family
FED51_RS04410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FED51_RS04410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FED51_RS04410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FED51_RS04420	COG3859	Proton-coupled thiamine transporter YuaJ
FED51_RS04425	COG1404	Belongs to the peptidase S8 family
FED51_RS04440	COG0018	arginyl-trna synthetase
FED51_RS04455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FED51_RS04475	COG1077	Cell shape determining protein MreB Mrl
FED51_RS04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS04480	COG1263	PTS System
FED51_RS04480	COG2190	(PTS) system
FED51_RS04485	COG3711	transcriptional antiterminator
FED51_RS04490	COG0561	phosphatase activity
FED51_RS04495	COG1349	DNA-binding transcription factor activity
FED51_RS04515	COG2207	Transcriptional regulator
FED51_RS04520	COG3011	Protein conserved in bacteria
FED51_RS04535	COG1404	Belongs to the peptidase S8 family
FED51_RS04545	COG0385	Bile acid
FED51_RS04555	COG0534	Mate efflux family protein
FED51_RS04565	COG0328	RNA-DNA hybrid ribonuclease activity
FED51_RS04565	COG3341	Caulimovirus viroplasmin
FED51_RS04575	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS04580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FED51_RS04590	COG1522	sequence-specific DNA binding
FED51_RS04595	COG2059	Chromate
FED51_RS04600	COG2059	Chromate
FED51_RS04610	COG0366	Alpha amylase catalytic
FED51_RS04615	COG2188	Transcriptional regulator
FED51_RS04620	COG1785	Belongs to the alkaline phosphatase family
FED51_RS04625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FED51_RS04630	COG0840	transmembrane signaling receptor activity
FED51_RS04635	COG1294	oxidase, subunit
FED51_RS04640	COG1271	oxidase subunit
FED51_RS04655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FED51_RS04665	COG0477	Major facilitator Superfamily
FED51_RS04675	COG0534	Mate efflux family protein
FED51_RS04680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FED51_RS04690	COG0535	radical SAM domain protein
FED51_RS04730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FED51_RS04735	COG4405	Protein conserved in bacteria
FED51_RS04750	COG1609	Transcriptional regulator
FED51_RS04755	COG1175	transmembrane transport
FED51_RS04760	COG0395	ABC-type sugar transport system, permease component
FED51_RS04765	COG5578	integral membrane protein
FED51_RS04770	COG1653	transport
FED51_RS04775	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FED51_RS04780	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FED51_RS04790	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FED51_RS04795	COG1447	Phosphotransferase system cellobiose-specific component IIA
FED51_RS04800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FED51_RS04805	COG1486	melibiose metabolic process
FED51_RS04810	COG3394	polysaccharide catabolic process
FED51_RS04815	COG2188	Transcriptional regulator
FED51_RS04830	COG1917	Cupin 2, conserved barrel domain protein
FED51_RS04835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FED51_RS04840	COG0456	acetyltransferase
FED51_RS04855	COG2137	regulation of response to DNA damage stimulus
FED51_RS04880	COG1988	membrane-bound metal-dependent
FED51_RS04890	COG1194	a g-specific adenine glycosylase
FED51_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS04915	COG0436	Aminotransferase
FED51_RS04925	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS04935	COG3557	Belongs to the UPF0374 family
FED51_RS04940	COG1132	(ABC) transporter
FED51_RS04945	COG4129	membrane
FED51_RS04950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FED51_RS04960	COG0640	Transcriptional regulator
FED51_RS04975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FED51_RS04980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FED51_RS04985	COG3870	Protein conserved in bacteria
FED51_RS04990	COG0735	belongs to the Fur family
FED51_RS05185	COG4824	toxin secretion phage lysis holin
FED51_RS05190	COG0860	N-Acetylmuramoyl-L-alanine amidase
FED51_RS05200	COG4974	Belongs to the 'phage' integrase family
FED51_RS05275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FED51_RS05285	COG1511	domain protein
FED51_RS05300	COG4499	WXG100 protein secretion system (Wss), protein YukC
FED51_RS05305	COG1674	ftsk spoiiie
FED51_RS05450	COG0457	Tetratricopeptide repeat
FED51_RS05495	COG5578	integral membrane protein
FED51_RS05500	COG1175	transmembrane transport
FED51_RS05505	COG0395	ABC-type sugar transport system, permease component
FED51_RS05510	COG1653	transport
FED51_RS05515	COG2972	Histidine kinase
FED51_RS05520	COG2207	Transcriptional regulator
FED51_RS05520	COG4753	response regulator
FED51_RS05540	COG1794	racemase activity, acting on amino acids and derivatives
FED51_RS05555	COG0456	acetyltransferase
FED51_RS05565	COG0523	cobalamin synthesis protein
FED51_RS05575	COG0701	Predicted permease
FED51_RS05590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FED51_RS05645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FED51_RS05650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FED51_RS05650	COG2207	Transcriptional regulator
FED51_RS05655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FED51_RS05660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FED51_RS05665	COG3829	transcription factor binding
FED51_RS05670	COG0833	amino acid
FED51_RS05675	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS05680	COG2738	Putative neutral zinc metallopeptidase
FED51_RS05685	COG1469	GTP cyclohydrolase I activity
FED51_RS05705	COG1309	transcriptional regulator
FED51_RS05710	COG1131	(ABC) transporter
FED51_RS05720	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS05725	COG0840	transmembrane signaling receptor activity
FED51_RS05730	COG0326	Molecular chaperone. Has ATPase activity
FED51_RS05740	COG0697	spore germination
FED51_RS05745	COG1733	regulation of RNA biosynthetic process
FED51_RS05750	COG0655	NAD(P)H dehydrogenase (quinone) activity
FED51_RS05755	COG0667	Aldo Keto reductase
FED51_RS05765	COG4637	Psort location Cytoplasmic, score
FED51_RS05775	COG0737	Belongs to the 5'-nucleotidase family
FED51_RS05780	COG0747	negative chemotaxis
FED51_RS05790	COG0783	Belongs to the Dps family
FED51_RS05805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FED51_RS05825	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS05830	COG4605	iron ion homeostasis
FED51_RS05835	COG4604	ABC transporter, ATP-binding protein
FED51_RS05840	COG4607	ABC-type enterochelin transport system periplasmic component
FED51_RS05845	COG2766	serine protein kinase
FED51_RS05855	COG2718	Belongs to the UPF0229 family
FED51_RS05865	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FED51_RS05870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FED51_RS05890	COG1120	ATPase activity
FED51_RS05905	COG1489	DNA binding
FED51_RS05915	COG2311	Membrane
FED51_RS05930	COG4585	Histidine kinase
FED51_RS05935	COG2197	response regulator
FED51_RS05950	COG1131	(ABC) transporter
FED51_RS05965	COG1959	2 iron, 2 sulfur cluster binding
FED51_RS05970	COG1017	nitric oxide dioxygenase activity
FED51_RS05970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FED51_RS05975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FED51_RS05995	COG1312	Catalyzes the dehydration of D-mannonate
FED51_RS06005	COG4209	transmembrane transport
FED51_RS06010	COG0395	ABC-type sugar transport system, permease component
FED51_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS06025	COG3546	catalase activity
FED51_RS06030	COG0473	3-isopropylmalate dehydrogenase activity
FED51_RS06035	COG0179	Fumarylacetoacetate (FAA) hydrolase
FED51_RS06040	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FED51_RS06040	COG2508	Transcriptional regulator
FED51_RS06045	COG0454	-acetyltransferase
FED51_RS06070	COG3344	reverse transcriptase
FED51_RS06085	COG0395	ABC-type sugar transport system, permease component
FED51_RS06095	COG0584	glycerophosphoryl diester phosphodiesterase
FED51_RS06100	COG1120	ATPase activity
FED51_RS06105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS06110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS06115	COG0058	SHG alpha-glucan phosphorylase activity
FED51_RS06120	COG0297	glycogen (starch) synthase activity
FED51_RS06125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FED51_RS06130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FED51_RS06140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FED51_RS06140	COG3153	acetyltransferase
FED51_RS06150	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FED51_RS06155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FED51_RS06160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FED51_RS06170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FED51_RS06180	COG0697	spore germination
FED51_RS06210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FED51_RS06215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FED51_RS06220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FED51_RS06225	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FED51_RS06235	COG0393	Putative heavy-metal-binding
FED51_RS06240	COG2719	SpoVR family
FED51_RS06245	COG3401	FG-GAP repeat protein
FED51_RS06250	COG2755	lipolytic protein G-D-S-L family
FED51_RS06255	COG3401	FG-GAP repeat protein
FED51_RS06260	COG1653	transport
FED51_RS06265	COG1175	transmembrane transport
FED51_RS06270	COG0395	ABC-type sugar transport system, permease component
FED51_RS06275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FED51_RS06280	COG5578	integral membrane protein
FED51_RS06285	COG2972	Histidine kinase
FED51_RS06290	COG4753	response regulator
FED51_RS06290	COG2207	Transcriptional regulator
FED51_RS06300	COG1132	(ABC) transporter
FED51_RS06305	COG1132	(ABC) transporter
FED51_RS06310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FED51_RS06315	COG0733	neurotransmitter:sodium symporter activity
FED51_RS06320	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FED51_RS06325	COG1960	acyl-CoA dehydrogenase activity
FED51_RS06330	COG0318	PFAM AMP-dependent synthetase and ligase
FED51_RS06335	COG0439	Biotin carboxylase
FED51_RS06340	COG0511	ligase activity, forming carbon-carbon bonds
FED51_RS06345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FED51_RS06350	COG1024	Enoyl-CoA hydratase
FED51_RS06355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FED51_RS06360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FED51_RS06375	COG3842	ATPase activity
FED51_RS06380	COG2508	Transcriptional regulator
FED51_RS06405	COG0189	ligase activity
FED51_RS06415	COG4399	Belongs to the UPF0754 family
FED51_RS06420	COG3679	Belongs to the UPF0342 family
FED51_RS06430	COG0534	Mate efflux family protein
FED51_RS06435	COG0561	phosphatase activity
FED51_RS06440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FED51_RS06450	COG5002	protein histidine kinase activity
FED51_RS06460	COG3344	reverse transcriptase
FED51_RS06465	COG1132	(ABC) transporter
FED51_RS06470	COG1132	(ABC) transporter
FED51_RS06490	COG1131	(ABC) transporter
FED51_RS06495	COG4152	abc transporter atp-binding protein
FED51_RS06500	COG1668	transmembrane transport
FED51_RS06510	COG0706	membrane insertase activity
FED51_RS06525	COG0745	RESPONSE REGULATOR receiver
FED51_RS06530	COG2205	protein histidine kinase activity
FED51_RS06530	COG2770	Histidine kinase
FED51_RS06535	COG2814	Major facilitator Superfamily
FED51_RS06540	COG3481	metal-dependent phosphohydrolase, HD sub domain
FED51_RS06550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FED51_RS06580	COG1846	Transcriptional regulator
FED51_RS06595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FED51_RS06605	COG0537	adenosine 5'-monophosphoramidase activity
FED51_RS06615	COG1131	(ABC) transporter
FED51_RS06620	COG4473	ABC transporter
FED51_RS06630	COG0785	Cytochrome C biogenesis protein
FED51_RS06640	COG1842	Phage shock protein A
FED51_RS06650	COG4758	membrane
FED51_RS06655	COG4585	Histidine kinase
FED51_RS06660	COG2197	response regulator
FED51_RS06665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FED51_RS06670	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FED51_RS06675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FED51_RS06680	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FED51_RS06700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FED51_RS06710	COG3290	protein histidine kinase activity
FED51_RS06715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FED51_RS06720	COG4492	Belongs to the UPF0735 family
FED51_RS06725	COG0077	Prephenate dehydratase
FED51_RS06730	COG1827	regulation of RNA biosynthetic process
FED51_RS06735	COG1104	cysteine desulfurase activity
FED51_RS06740	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FED51_RS06745	COG0157	Belongs to the NadC ModD family
FED51_RS06750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FED51_RS06770	COG0632	four-way junction helicase activity
FED51_RS06775	COG2255	four-way junction helicase activity
FED51_RS06785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FED51_RS06790	COG0343	queuine tRNA-ribosyltransferase activity
FED51_RS06795	COG1862	Preprotein translocase
FED51_RS06810	COG2323	membrane
FED51_RS06820	COG2244	polysaccharide biosynthetic process
FED51_RS06835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FED51_RS06835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FED51_RS06840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FED51_RS06840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FED51_RS06845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FED51_RS06850	COG5416	Lipopolysaccharide assembly protein A domain
FED51_RS06855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FED51_RS06855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FED51_RS06860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FED51_RS06865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FED51_RS06870	COG1490	D-aminoacyl-tRNA deacylase activity
FED51_RS06875	COG1653	transport
FED51_RS06895	COG0673	inositol 2-dehydrogenase activity
FED51_RS06900	COG1082	Xylose isomerase domain protein TIM barrel
FED51_RS06905	COG1609	Transcriptional regulator
FED51_RS06910	COG0124	histidyl-tRNA synthetase
FED51_RS06915	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FED51_RS06925	COG0460	homoserine dehydrogenase
FED51_RS06940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FED51_RS06950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FED51_RS06955	COG2364	Membrane
FED51_RS06960	COG1959	2 iron, 2 sulfur cluster binding
FED51_RS06965	COG1104	cysteine desulfurase activity
FED51_RS06970	COG0482	sulfurtransferase activity
FED51_RS06980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FED51_RS06985	COG3881	PFAM PRC-barrel domain
FED51_RS07000	COG0628	permease
FED51_RS07005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FED51_RS07010	COG4472	Bacterial protein of unknown function (DUF965)
FED51_RS07015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FED51_RS07020	COG3906	Belongs to the UPF0473 family
FED51_RS07025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FED51_RS07030	COG4122	O-methyltransferase activity
FED51_RS07035	COG0826	peptidase U32
FED51_RS07040	COG0826	peptidase U32
FED51_RS07045	COG0572	uridine kinase
FED51_RS07050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FED51_RS07065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FED51_RS07090	COG1115	amino acid carrier protein
FED51_RS07120	COG1396	sequence-specific DNA binding
FED51_RS07125	COG2323	membrane
FED51_RS07145	COG0860	N-Acetylmuramoyl-L-alanine amidase
FED51_RS07190	COG3397	chitin binding
FED51_RS07205	COG0753	catalase activity
FED51_RS07215	COG0776	regulation of translation
FED51_RS07220	COG1183	phosphatidylcholine synthase activity
FED51_RS07225	COG0688	phosphatidylethanolamine metabolic process
FED51_RS07235	COG1320	monovalent cation:proton antiporter activity
FED51_RS07240	COG2212	antiporter activity
FED51_RS07245	COG1863	multisubunit Na H antiporter MnhE subunit
FED51_RS07250	COG0651	ATP synthesis coupled electron transport
FED51_RS07255	COG1006	Multisubunit Na H antiporter MnhC subunit
FED51_RS07260	COG2111	Na H antiporter
FED51_RS07265	COG2111	Na H antiporter
FED51_RS07265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FED51_RS07280	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FED51_RS07285	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FED51_RS07290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FED51_RS07295	COG1534	Rna-binding protein
FED51_RS07300	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FED51_RS07305	COG1713	HD superfamily hydrolase involved in NAD metabolism
FED51_RS07310	COG0799	negative regulation of ribosome biogenesis
FED51_RS07315	COG2996	Protein conserved in bacteria
FED51_RS07320	COG2226	methyltransferase
FED51_RS07325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FED51_RS07335	COG1596	polysaccharide export
FED51_RS07335	COG1555	photosystem II stabilization
FED51_RS07340	COG2131	deaminase
FED51_RS07345	COG0658	competence protein
FED51_RS07345	COG2333	competence protein COMEC
FED51_RS07355	COG1466	dna polymerase III delta subunit
FED51_RS07360	COG0268	Binds directly to 16S ribosomal RNA
FED51_RS07365	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FED51_RS07375	COG0481	GTPase activity
FED51_RS07380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FED51_RS07385	COG1420	regulation of RNA biosynthetic process
FED51_RS07390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FED51_RS07395	COG0443	Heat shock 70 kDa protein
FED51_RS07400	COG0484	heat shock protein binding
FED51_RS07405	COG2264	protein methyltransferase activity
FED51_RS07410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FED51_RS07415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FED51_RS07420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FED51_RS07425	COG1283	sodium-dependent phosphate transmembrane transporter activity
FED51_RS07430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FED51_RS07435	COG1610	YqeY-like protein
FED51_RS07440	COG1030	water channel activity
FED51_RS07445	COG4864	UPF0365 protein
FED51_RS07465	COG1702	phosphate starvation-inducible protein PhoH
FED51_RS07470	COG1480	7TM receptor with intracellular HD hydrolase
FED51_RS07475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FED51_RS07480	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FED51_RS07490	COG0295	cytidine deaminase activity
FED51_RS07495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FED51_RS07505	COG1381	Involved in DNA repair and RecF pathway recombination
FED51_RS07510	COG0752	glycyl-tRNA synthetase alpha subunit
FED51_RS07515	COG0751	glycine-tRNA ligase activity
FED51_RS07520	COG0517	IMP dehydrogenase activity
FED51_RS07525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FED51_RS07530	COG1671	Belongs to the UPF0178 family
FED51_RS07535	COG0358	DNA primase activity
FED51_RS07540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FED51_RS07550	COG2010	Cytochrome c
FED51_RS07555	COG2384	SAM-dependent methyltransferase
FED51_RS07560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FED51_RS07590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FED51_RS07595	COG1329	Transcriptional regulator
FED51_RS07605	COG0513	Belongs to the DEAD box helicase family
FED51_RS07610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FED51_RS07620	COG5002	protein histidine kinase activity
FED51_RS07625	COG1121	(ABC) transporter
FED51_RS07630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FED51_RS07640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FED51_RS07650	COG1121	(ABC) transporter
FED51_RS07655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FED51_RS07660	COG0735	belongs to the Fur family
FED51_RS07675	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FED51_RS07680	COG4709	membrane
FED51_RS07685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FED51_RS07695	COG2814	Major facilitator Superfamily
FED51_RS07700	COG4086	secreted protein
FED51_RS07715	COG0704	Plays a role in the regulation of phosphate uptake
FED51_RS07745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FED51_RS07750	COG0477	Major facilitator Superfamily
FED51_RS07760	COG0768	penicillin binding
FED51_RS07780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FED51_RS07785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FED51_RS07790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FED51_RS07800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FED51_RS07810	COG0457	Tetratricopeptide repeat
FED51_RS07810	COG0705	Rhomboid family
FED51_RS07820	COG0697	spore germination
FED51_RS07830	COG4483	Protein conserved in bacteria
FED51_RS07835	COG1940	carbohydrate kinase activity
FED51_RS07840	COG1027	Aspartate ammonia-lyase
FED51_RS07845	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS07855	COG0352	thiamine-phosphate diphosphorylase activity
FED51_RS07865	COG2022	thiamine diphosphate biosynthetic process
FED51_RS07870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FED51_RS07875	COG0351	phosphomethylpyrimidine kinase
FED51_RS07885	COG0011	TIGRFAM Protein of
FED51_RS07890	COG2153	protein acetylation
FED51_RS07895	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FED51_RS07900	COG2382	esterase
FED51_RS07905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FED51_RS07915	COG1396	sequence-specific DNA binding
FED51_RS07925	COG0114	fumarate hydratase activity
FED51_RS07930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FED51_RS07935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FED51_RS07940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FED51_RS07960	COG0456	acetyltransferase
FED51_RS07980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FED51_RS07985	COG0730	response to heat
FED51_RS07990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FED51_RS07995	COG0765	amino acid transport
FED51_RS08000	COG1126	abc transporter atp-binding protein
FED51_RS08005	COG4129	membrane
FED51_RS08010	COG1376	ErfK ybiS ycfS ynhG family protein
FED51_RS08025	COG0346	lactoylglutathione lyase activity
FED51_RS08030	COG2195	Cleaves the N-terminal amino acid of tripeptides
FED51_RS08045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FED51_RS08055	COG2257	FlhB HrpN YscU SpaS Family
FED51_RS08060	COG1516	flagellar protein fliS
FED51_RS08070	COG1728	Protein conserved in bacteria
FED51_RS08085	COG1902	pentaerythritol trinitrate reductase activity
FED51_RS08090	COG0517	IMP dehydrogenase activity
FED51_RS08110	COG0175	sulfate reduction
FED51_RS08115	COG2046	Belongs to the sulfate adenylyltransferase family
FED51_RS08120	COG0306	phosphate transporter
FED51_RS08125	COG0529	Catalyzes the synthesis of activated sulfate
FED51_RS08135	COG2861	carbohydrate metabolic process
FED51_RS08140	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS08145	COG0789	Transcriptional regulator
FED51_RS08150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FED51_RS08150	COG1587	Uroporphyrinogen-III synthase
FED51_RS08160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FED51_RS08160	COG1648	precorrin-2 dehydrogenase activity
FED51_RS08180	COG0527	aspartate kinase activity
FED51_RS08195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FED51_RS08200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FED51_RS08205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FED51_RS08210	COG0300	oxidoreductase activity
FED51_RS08220	COG0367	asparagine synthase
FED51_RS08230	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS08250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FED51_RS08255	COG2190	(PTS) system
FED51_RS08270	COG0701	Predicted permease
FED51_RS08275	COG0523	cobalamin synthesis protein
FED51_RS08285	COG1968	undecaprenyl-diphosphatase activity
FED51_RS08290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FED51_RS08310	COG1379	DNA repair
FED51_RS08315	COG1300	Membrane
FED51_RS08320	COG0735	belongs to the Fur family
FED51_RS08330	COG4974	Belongs to the 'phage' integrase family
FED51_RS08335	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FED51_RS08355	COG3832	glyoxalase III activity
FED51_RS08360	COG1686	Belongs to the peptidase S11 family
FED51_RS08370	COG2172	sigma factor antagonist activity
FED51_RS08375	COG1191	sigma factor activity
FED51_RS08385	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FED51_RS08400	COG0697	spore germination
FED51_RS08405	COG0019	diaminopimelate decarboxylase activity
FED51_RS08415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FED51_RS08420	COG3347	Dehydrogenase
FED51_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS08425	COG1070	Carbohydrate kinase
FED51_RS08430	COG4806	L-rhamnose isomerase
FED51_RS08435	COG1349	DNA-binding transcription factor activity
FED51_RS08440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FED51_RS08440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FED51_RS08445	COG0307	riboflavin synthase, alpha
FED51_RS08450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FED51_RS08450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FED51_RS08455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FED51_RS08465	COG1547	Domain of unknown function (DUF309)
FED51_RS08470	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FED51_RS08475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FED51_RS08490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FED51_RS08500	COG2323	membrane
FED51_RS08520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FED51_RS08535	COG2323	membrane
FED51_RS08540	COG1686	Belongs to the peptidase S11 family
FED51_RS08545	COG2715	membrane protein required for spore maturation
FED51_RS08550	COG0700	Nucleoside recognition
FED51_RS08555	COG1187	pseudouridine synthase activity
FED51_RS08560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FED51_RS08565	COG1333	cytochrome c biogenesis protein
FED51_RS08570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FED51_RS08575	COG0745	RESPONSE REGULATOR receiver
FED51_RS08580	COG5002	protein histidine kinase activity
FED51_RS08600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FED51_RS08605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS08610	COG1120	ATPase activity
FED51_RS08615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FED51_RS08620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FED51_RS08625	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FED51_RS08630	COG1492	cobalamin metabolic process
FED51_RS08635	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FED51_RS08650	COG2096	Adenosyltransferase
FED51_RS08655	COG2720	vancomycin resistance protein
FED51_RS08675	COG0739	heme binding
FED51_RS08685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FED51_RS08695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FED51_RS08700	COG1141	Ferredoxin
FED51_RS08705	COG4955	Helix-turn-helix domain
FED51_RS08710	COG0514	ATP-dependent DNA helicase (RecQ)
FED51_RS08715	COG1266	CAAX protease self-immunity
FED51_RS08735	COG2105	PFAM AIG2 family protein
FED51_RS08740	COG1473	amidohydrolase
FED51_RS08745	COG0456	acetyltransferase
FED51_RS08750	COG1595	DNA-templated transcription, initiation
FED51_RS08765	COG1408	metallophosphoesterase
FED51_RS08775	COG4862	establishment of competence for transformation
FED51_RS08780	COG1181	Belongs to the D-alanine--D-alanine ligase family
FED51_RS08785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FED51_RS08790	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS08795	COG0252	asparaginase activity
FED51_RS08800	COG2339	peptidase activity
FED51_RS08805	COG0626	cystathionine gamma-synthase activity
FED51_RS08810	COG0626	cystathionine gamma-synthase activity
FED51_RS08815	COG0646	methionine synthase
FED51_RS08815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FED51_RS08820	COG0646	methionine synthase
FED51_RS08820	COG1410	methionine synthase
FED51_RS08825	COG3773	Cell wall hydrolase
FED51_RS08825	COG3409	Peptidoglycan-binding domain 1 protein
FED51_RS08830	COG2959	enzyme of heme biosynthesis
FED51_RS08840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FED51_RS08845	COG0204	Acyl-transferase
FED51_RS08850	COG0539	negative regulation of cytoplasmic translation
FED51_RS08860	COG1160	GTP binding
FED51_RS08865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FED51_RS08870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FED51_RS08890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FED51_RS08895	COG0302	gtp cyclohydrolase
FED51_RS08905	COG0142	geranyltranstransferase activity
FED51_RS08910	COG2226	methyltransferase
FED51_RS08915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FED51_RS08920	COG0163	prenyltransferase activity
FED51_RS08925	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FED51_RS08935	COG0105	UTP biosynthetic process
FED51_RS08940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FED51_RS08945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FED51_RS08950	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FED51_RS08965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FED51_RS08970	COG0134	indole-3-glycerol-phosphate synthase activity
FED51_RS08975	COG0135	phosphoribosylanthranilate isomerase activity
FED51_RS08980	COG0133	tryptophan synthase activity
FED51_RS08985	COG0159	tryptophan synthase activity
FED51_RS08990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FED51_RS08995	COG0287	Prephenate dehydrogenase
FED51_RS09000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FED51_RS09010	COG0457	Tetratricopeptide repeat
FED51_RS09015	COG5582	Belongs to the UPF0302 family
FED51_RS09025	COG0723	plastoquinol--plastocyanin reductase activity
FED51_RS09035	COG2010	Cytochrome c
FED51_RS09035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FED51_RS09040	COG4347	Protein of unknown function (DUF1405)
FED51_RS09050	COG2738	Putative neutral zinc metallopeptidase
FED51_RS09055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FED51_RS09060	COG1694	Mazg nucleotide pyrophosphohydrolase
FED51_RS09065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FED51_RS09070	COG1803	Methylglyoxal synthase
FED51_RS09075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FED51_RS09080	COG0438	transferase activity, transferring glycosyl groups
FED51_RS09085	COG0617	tRNA 3'-terminal CCA addition
FED51_RS09090	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FED51_RS09090	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FED51_RS09095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FED51_RS09100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FED51_RS09105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FED51_RS09115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FED51_RS09115	COG1199	ATP-dependent helicase activity
FED51_RS09120	COG0402	S-adenosylhomocysteine deaminase activity
FED51_RS09140	COG0017	Asparaginyl-tRNA synthetase
FED51_RS09145	COG3935	DnaD domain protein
FED51_RS09150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FED51_RS09160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FED51_RS09165	COG4499	WXG100 protein secretion system (Wss), protein YukC
FED51_RS09165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FED51_RS09170	COG3331	DNA recombination
FED51_RS09180	COG0789	Transcriptional regulator
FED51_RS09195	COG2860	membrane
FED51_RS09205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FED51_RS09210	COG0835	chemotaxis
FED51_RS09210	COG0784	Response regulator, receiver
FED51_RS09215	COG1234	tRNA 3'-trailer cleavage
FED51_RS09240	COG1413	lyase activity
FED51_RS09250	COG3402	PFAM membrane-flanked domain
FED51_RS09255	COG3428	Bacterial PH domain
FED51_RS09285	COG0067	glutamate synthase
FED51_RS09285	COG0069	glutamate synthase activity
FED51_RS09285	COG0070	glutamate synthase
FED51_RS09290	COG0493	'glutamate synthase
FED51_RS09320	COG2508	Transcriptional regulator
FED51_RS09330	COG0460	homoserine dehydrogenase
FED51_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS09340	COG0006	proline dipeptidase activity
FED51_RS09355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FED51_RS09375	COG0561	phosphatase activity
FED51_RS09380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FED51_RS09395	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FED51_RS09415	COG1136	(ABC) transporter
FED51_RS09420	COG2124	cytochrome p450
FED51_RS09435	COG3048	D-serine ammonia-lyase activity
FED51_RS09440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FED51_RS09445	COG1205	dead DEAH box helicase
FED51_RS09445	COG1111	helicase
FED51_RS09450	COG3359	exonuclease
FED51_RS09460	COG4474	Belongs to the UPF0398 family
FED51_RS09465	COG3599	regulation of cell shape
FED51_RS09470	COG0328	RNA-DNA hybrid ribonuclease activity
FED51_RS09480	COG0116	Belongs to the methyltransferase superfamily
FED51_RS09485	COG1115	amino acid carrier protein
FED51_RS09495	COG1597	lipid kinase activity
FED51_RS09500	COG2814	Major facilitator Superfamily
FED51_RS09515	COG0346	lactoylglutathione lyase activity
FED51_RS09520	COG1834	amidinotransferase
FED51_RS09550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FED51_RS09555	COG2207	Transcriptional regulator
FED51_RS09555	COG0662	Cupin 2, conserved barrel domain protein
FED51_RS09560	COG0583	DNA-binding transcription factor activity
FED51_RS09575	COG1690	Belongs to the RtcB family
FED51_RS09580	COG0523	cobalamin synthesis protein
FED51_RS09590	COG1199	ATP-dependent helicase activity
FED51_RS09595	COG1966	Carbon starvation protein
FED51_RS09605	COG0003	Pfam Anion-transporting ATPase
FED51_RS09620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FED51_RS09625	COG0444	Belongs to the ABC transporter superfamily
FED51_RS09630	COG4608	Belongs to the ABC transporter superfamily
FED51_RS09635	COG1744	ABC transporter substrate-binding protein PnrA-like
FED51_RS09640	COG3852	Histidine kinase
FED51_RS09645	COG2340	Cysteine-rich secretory protein family
FED51_RS09650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FED51_RS09660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FED51_RS09670	COG1078	dGTPase activity
FED51_RS09695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FED51_RS09700	COG1984	allophanate hydrolase subunit 2
FED51_RS09705	COG1414	Transcriptional regulator
FED51_RS09710	COG1914	H( )-stimulated, divalent metal cation uptake system
FED51_RS09715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FED51_RS09720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FED51_RS09725	COG0022	dehydrogenase e1 component
FED51_RS09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
FED51_RS09735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FED51_RS09740	COG3284	Transcriptional regulator
FED51_RS09745	COG0840	transmembrane signaling receptor activity
FED51_RS09750	COG4122	O-methyltransferase activity
FED51_RS09755	COG1063	alcohol dehydrogenase
FED51_RS09760	COG1620	l-lactate permease
FED51_RS09765	COG0247	lactate metabolic process
FED51_RS09770	COG1139	Iron-sulfur cluster binding protein
FED51_RS09775	COG1556	Lactate utilization protein
FED51_RS09780	COG2186	Transcriptional regulator
FED51_RS09790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FED51_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS09830	COG1609	Transcriptional regulator
FED51_RS09835	COG1263	PTS System
FED51_RS09835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS09840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FED51_RS09845	COG1621	beta-fructofuranosidase activity
FED51_RS09860	COG3534	alpha-L-arabinofuranosidase
FED51_RS09870	COG0371	Dehydrogenase
FED51_RS09875	COG5578	integral membrane protein
FED51_RS09885	COG1175	transmembrane transport
FED51_RS09890	COG0395	ABC-type sugar transport system, permease component
FED51_RS09895	COG3940	Belongs to the glycosyl hydrolase 43 family
FED51_RS09915	COG0235	Class ii aldolase
FED51_RS09920	COG1069	ribulokinase activity
FED51_RS09925	COG2160	L-arabinose isomerase activity
FED51_RS09930	COG3534	alpha-L-arabinofuranosidase
FED51_RS09935	COG1609	Transcriptional regulator
FED51_RS09950	COG3507	Belongs to the glycosyl hydrolase 43 family
FED51_RS09970	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FED51_RS09985	COG2357	RelA SpoT domain protein
FED51_RS09995	COG1309	transcriptional regulator
FED51_RS10000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FED51_RS10010	COG2318	DinB family
FED51_RS10020	COG2318	DinB family
FED51_RS10025	COG0494	nUDIX hydrolase
FED51_RS10030	COG0768	penicillin binding
FED51_RS10045	COG1797	cobyrinic acid a,c-diamide synthase activity
FED51_RS10055	COG0488	(ABC) transporter
FED51_RS10060	COG0697	spore germination
FED51_RS10070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FED51_RS10075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FED51_RS10085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FED51_RS10090	COG0860	N-Acetylmuramoyl-L-alanine amidase
FED51_RS10095	COG1501	Belongs to the glycosyl hydrolase 31 family
FED51_RS10100	COG2207	Transcriptional regulator
FED51_RS10100	COG1917	Cupin 2, conserved barrel domain protein
FED51_RS10105	COG5578	integral membrane protein
FED51_RS10115	COG2972	Histidine kinase
FED51_RS10125	COG4209	transmembrane transport
FED51_RS10130	COG0395	ABC-type sugar transport system, permease component
FED51_RS10160	COG3852	Histidine kinase
FED51_RS10190	COG1175	transmembrane transport
FED51_RS10195	COG0395	ABC-type sugar transport system, permease component
FED51_RS10200	COG5578	integral membrane protein
FED51_RS10205	COG1609	Transcriptional regulator
FED51_RS10210	COG1404	Belongs to the peptidase S8 family
FED51_RS10215	COG0697	spore germination
FED51_RS10220	COG0318	PFAM AMP-dependent synthetase and ligase
FED51_RS10225	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FED51_RS10235	COG0697	spore germination
FED51_RS10245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FED51_RS10260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FED51_RS10270	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FED51_RS10280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FED51_RS10290	COG0745	RESPONSE REGULATOR receiver
FED51_RS10295	COG5002	protein histidine kinase activity
FED51_RS10300	COG2239	Acts as a magnesium transporter
FED51_RS10310	COG0384	phenazine biosynthesis protein PhzF
FED51_RS10315	COG1063	alcohol dehydrogenase
FED51_RS10335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FED51_RS10340	COG4977	sequence-specific DNA binding
FED51_RS10360	COG2323	membrane
FED51_RS10375	COG2323	membrane
FED51_RS10410	COG0693	protein deglycase activity
FED51_RS10410	COG0753	catalase activity
FED51_RS10420	COG2986	histidine ammonia-lyase
FED51_RS10425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FED51_RS10430	COG1228	amidohydrolase
FED51_RS10435	COG0010	Belongs to the arginase family
FED51_RS10440	COG2056	Na+-H+ antiporter family
FED51_RS10445	COG0457	Tetratricopeptide repeat
FED51_RS10450	COG0697	spore germination
FED51_RS10470	COG2972	Histidine kinase
FED51_RS10470	COG0745	RESPONSE REGULATOR receiver
FED51_RS10490	COG3279	Response regulator of the LytR AlgR family
FED51_RS10500	COG1609	Transcriptional regulator
FED51_RS10505	COG2182	Extracellular solute-binding protein
FED51_RS10510	COG1175	transmembrane transport
FED51_RS10515	COG3833	ABC-type maltose transport systems, permease component
FED51_RS10520	COG1874	Beta-galactosidase
FED51_RS10525	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FED51_RS10530	COG0488	(ABC) transporter
FED51_RS10580	COG5646	InterPro IPR014922
FED51_RS10600	COG0312	modulator of DNA gyrase
FED51_RS10605	COG0312	modulator of DNA gyrase
FED51_RS10615	COG2814	Major facilitator Superfamily
FED51_RS10625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FED51_RS10665	COG0457	Tetratricopeptide repeat
FED51_RS10670	COG0431	NADPH-dependent FMN reductase
FED51_RS10675	COG2226	methyltransferase
FED51_RS10710	COG0586	Pfam SNARE associated Golgi protein
FED51_RS10720	COG1683	Conserved Protein
FED51_RS10730	COG1846	Transcriptional regulator
FED51_RS10735	COG0477	Major facilitator Superfamily
FED51_RS10790	COG0747	negative chemotaxis
FED51_RS10795	COG0601	transmembrane transport
FED51_RS10800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FED51_RS10805	COG0444	Belongs to the ABC transporter superfamily
FED51_RS10810	COG1124	(ABC) transporter
FED51_RS10820	COG1404	Belongs to the peptidase S8 family
FED51_RS10825	COG0583	DNA-binding transcription factor activity
FED51_RS10840	COG2197	response regulator
FED51_RS10845	COG1131	(ABC) transporter
FED51_RS10855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FED51_RS10860	COG0583	DNA-binding transcription factor activity
FED51_RS10875	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FED51_RS10885	COG5578	integral membrane protein
FED51_RS10890	COG4753	response regulator
FED51_RS10890	COG2207	Transcriptional regulator
FED51_RS10890	COG2207	Transcriptional regulator
FED51_RS10890	COG4753	response regulator
FED51_RS10895	COG2972	Histidine kinase
FED51_RS10905	COG4209	transmembrane transport
FED51_RS10910	COG0395	ABC-type sugar transport system, permease component
FED51_RS10925	COG2814	Major facilitator Superfamily
FED51_RS10930	COG0583	DNA-binding transcription factor activity
FED51_RS10935	COG2197	response regulator
FED51_RS10945	COG3693	PFAM glycoside hydrolase, family 10
FED51_RS10975	COG1396	sequence-specific DNA binding
FED51_RS11000	COG0681	Belongs to the peptidase S26 family
FED51_RS11010	COG1620	l-lactate permease
FED51_RS11015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FED51_RS11020	COG0277	FAD linked oxidase domain protein
FED51_RS11025	COG0247	lactate metabolic process
FED51_RS11030	COG0277	FAD linked oxidase domain protein
FED51_RS11035	COG1414	Transcriptional regulator
FED51_RS11040	COG1988	membrane-bound metal-dependent
FED51_RS11045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FED51_RS11050	COG0187	DNA topoisomerase II activity
FED51_RS11055	COG1832	CoA-binding protein
FED51_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS11070	COG1309	transcriptional regulator
FED51_RS11075	COG1511	domain protein
FED51_RS11085	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FED51_RS11090	COG4841	protein insertion into membrane
FED51_RS11100	COG1011	Hydrolase
FED51_RS11105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FED51_RS11110	COG1247	-acetyltransferase
FED51_RS11115	COG0656	L-ascorbic acid biosynthetic process
FED51_RS11120	COG0346	lactoylglutathione lyase activity
FED51_RS11125	COG3069	C4-dicarboxylate transmembrane transporter activity
FED51_RS11130	COG1587	Uroporphyrinogen-III synthase
FED51_RS11145	COG0673	inositol 2-dehydrogenase activity
FED51_RS11150	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FED51_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS11160	COG1349	DNA-binding transcription factor activity
FED51_RS11170	COG1280	lysine exporter protein (LysE YggA)
FED51_RS11175	COG1113	amino acid transport
FED51_RS11185	COG2151	metal-sulfur cluster biosynthetic enzyme
FED51_RS11190	COG0400	carboxylic ester hydrolase activity
FED51_RS11195	COG0346	lactoylglutathione lyase activity
FED51_RS11205	COG0697	spore germination
FED51_RS11210	COG1960	acyl-CoA dehydrogenase activity
FED51_RS11215	COG0542	response to heat
FED51_RS11220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FED51_RS11235	COG1404	Belongs to the peptidase S8 family
FED51_RS11250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FED51_RS11255	COG3546	catalase activity
FED51_RS11280	COG0436	Aminotransferase
FED51_RS11295	COG0180	Tryptophanyl-tRNA synthetase
FED51_RS11300	COG2323	membrane
FED51_RS11305	COG0586	Pfam SNARE associated Golgi protein
FED51_RS11320	COG0508	dehydrogenase complex catalyzes the overall conversion of
FED51_RS11325	COG0567	Dehydrogenase, E1 component
FED51_RS11335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FED51_RS11340	COG3285	dna ligase
FED51_RS11340	COG1793	dna ligase
FED51_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS11350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FED51_RS11360	COG2197	response regulator
FED51_RS11365	COG4585	Histidine kinase
FED51_RS11365	COG2203	Gaf domain
FED51_RS11375	COG1263	PTS System
FED51_RS11375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS11390	COG1609	Transcriptional regulator
FED51_RS11395	COG0673	inositol 2-dehydrogenase activity
FED51_RS11400	COG0673	inositol 2-dehydrogenase activity
FED51_RS11405	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FED51_RS11415	COG0395	ABC-type sugar transport system, permease component
FED51_RS11420	COG1175	transmembrane transport
FED51_RS11425	COG1653	transport
FED51_RS11430	COG1609	Transcriptional regulator
FED51_RS11435	COG1486	melibiose metabolic process
FED51_RS11440	COG2207	Transcriptional regulator
FED51_RS11460	COG0745	RESPONSE REGULATOR receiver
FED51_RS11470	COG0778	Nitroreductase
FED51_RS11475	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS11480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FED51_RS11505	COG2312	Erythromycin esterase
FED51_RS11510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FED51_RS11520	COG0720	synthase
FED51_RS11525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FED51_RS11530	COG2309	aminopeptidase activity
FED51_RS11550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FED51_RS11555	COG3314	Sporulation integral membrane protein YlbJ
FED51_RS11565	COG4841	protein insertion into membrane
FED51_RS11575	COG1509	lysine 2,3-aminomutase activity
FED51_RS11590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FED51_RS11595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FED51_RS11600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FED51_RS11610	COG0784	Response regulator, receiver
FED51_RS11610	COG0835	chemotaxis
FED51_RS11615	COG5002	protein histidine kinase activity
FED51_RS11615	COG5002	protein histidine kinase activity
FED51_RS11620	COG0745	RESPONSE REGULATOR receiver
FED51_RS11650	COG1119	ATPase activity
FED51_RS11675	COG0840	transmembrane signaling receptor activity
FED51_RS11685	COG2200	EAL domain
FED51_RS11690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FED51_RS11695	COG2267	carboxylic ester hydrolase activity
FED51_RS11700	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FED51_RS11705	COG0328	RNA-DNA hybrid ribonuclease activity
FED51_RS11710	COG0613	PHP domain protein
FED51_RS11720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FED51_RS11735	COG0824	Thioesterase
FED51_RS11740	COG0464	growth
FED51_RS11755	COG1388	LysM domain
FED51_RS11755	COG3858	chitin binding
FED51_RS11760	COG0398	Pfam SNARE associated Golgi protein
FED51_RS11780	COG2323	membrane
FED51_RS11785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FED51_RS11800	COG1607	acyl-coa hydrolase
FED51_RS11810	COG1288	antiporter activity
FED51_RS11815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FED51_RS11820	COG1082	Xylose isomerase domain protein TIM barrel
FED51_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS11835	COG1609	Transcriptional regulator
FED51_RS11840	COG0191	fructose-bisphosphate aldolase activity
FED51_RS11845	COG1082	Xylose isomerase domain protein TIM barrel
FED51_RS11850	COG0673	inositol 2-dehydrogenase activity
FED51_RS11855	COG1082	Xylose isomerase domain protein TIM barrel
FED51_RS11860	COG3962	Belongs to the TPP enzyme family
FED51_RS11865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FED51_RS11870	COG3718	enzyme involved in inositol metabolism
FED51_RS11875	COG1172	Belongs to the binding-protein-dependent transport system permease family
FED51_RS11880	COG1129	ABC transporter
FED51_RS11915	COG0686	Belongs to the AlaDH PNT family
FED51_RS11925	COG2226	methyltransferase
FED51_RS11935	COG4846	Membrane protein involved in cytochrome C biogenesis
FED51_RS11945	COG1132	(ABC) transporter
FED51_RS11950	COG1132	(ABC) transporter
FED51_RS11955	COG3763	UPF0154 protein
FED51_RS11965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FED51_RS11970	COG4224	UPF0291 protein
FED51_RS11975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FED51_RS11985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FED51_RS11995	COG0174	glutamine synthetase
FED51_RS12000	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FED51_RS12005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FED51_RS12010	COG0464	growth
FED51_RS12020	COG1923	regulation of RNA biosynthetic process
FED51_RS12025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FED51_RS12030	COG2136	Putative SAM-dependent methyltransferase
FED51_RS12030	COG2521	methyltransferase
FED51_RS12035	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FED51_RS12040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FED51_RS12055	COG4550	Control of competence regulator ComK, YlbF/YmcA
FED51_RS12060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FED51_RS12065	COG1013	pyruvate-flavodoxin oxidoreductase activity
FED51_RS12070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FED51_RS12070	COG0674	pyruvate-flavodoxin oxidoreductase activity
FED51_RS12075	COG2359	stage V sporulation protein S
FED51_RS12080	COG1692	metallophosphoesterase
FED51_RS12085	COG1418	mRNA catabolic process
FED51_RS12100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FED51_RS12110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FED51_RS12115	COG0513	Belongs to the DEAD box helicase family
FED51_RS12120	COG1058	Belongs to the CinA family
FED51_RS12120	COG1546	Belongs to the CinA family
FED51_RS12125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FED51_RS12130	COG1666	GTP binding
FED51_RS12135	COG1426	Protein conserved in bacteria
FED51_RS12150	COG0300	oxidoreductase activity
FED51_RS12155	COG0612	Peptidase, M16
FED51_RS12160	COG0612	Peptidase, M16
FED51_RS12165	COG2188	Transcriptional regulator
FED51_RS12170	COG1674	ftsk spoiiie
FED51_RS12180	COG0740	serine-type endopeptidase activity
FED51_RS12185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FED51_RS12190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FED51_RS12195	COG0527	aspartate kinase activity
FED51_RS12200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FED51_RS12205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FED51_RS12210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FED51_RS12215	COG1873	PFAM PRC-barrel domain
FED51_RS12220	COG0612	Peptidase, M16
FED51_RS12225	COG0726	polysaccharide deacetylase
FED51_RS12230	COG1185	polyribonucleotide nucleotidyltransferase activity
FED51_RS12235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FED51_RS12240	COG0196	riboflavin kinase activity
FED51_RS12245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FED51_RS12250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FED51_RS12255	COG1550	Protein conserved in bacteria
FED51_RS12260	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FED51_RS12265	COG1358	cellular component organization or biogenesis
FED51_RS12270	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FED51_RS12275	COG0195	Participates in both transcription termination and antitermination
FED51_RS12280	COG0779	Required for maturation of 30S ribosomal subunits
FED51_RS12285	COG2176	DNA-directed DNA polymerase activity
FED51_RS12290	COG0442	prolyl-tRNA aminoacylation
FED51_RS12295	COG0750	zinc metalloprotease
FED51_RS12300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FED51_RS12305	COG4589	Belongs to the CDS family
FED51_RS12310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FED51_RS12315	COG0233	cytoplasmic translational termination
FED51_RS12320	COG0528	UMP kinase activity
FED51_RS12325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FED51_RS12330	COG0052	Belongs to the universal ribosomal protein uS2 family
FED51_RS12350	COG1191	sigma factor activity
FED51_RS12360	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FED51_RS12365	COG1776	CheC inhibitor of MCP methylation
FED51_RS12370	COG2201	protein-glutamate methylesterase activity
FED51_RS12375	COG0455	bacterial-type flagellum organization
FED51_RS12380	COG1419	protein localization to endoplasmic reticulum
FED51_RS12385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FED51_RS12390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FED51_RS12395	COG1684	flagellar biosynthetic protein fliR
FED51_RS12400	COG1987	bacterial-type flagellum assembly
FED51_RS12405	COG1338	Plays a role in the flagellum-specific transport system
FED51_RS12410	COG3190	flagellar
FED51_RS12415	COG2201	protein-glutamate methylesterase activity
FED51_RS12420	COG1776	CheC inhibitor of MCP methylation
FED51_RS12420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FED51_RS12425	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FED51_RS12435	COG1582	Flagellar protein (FlbD)
FED51_RS12440	COG4786	Flagellar basal body rod
FED51_RS12450	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FED51_RS12470	COG1157	protein secretion by the type III secretion system
FED51_RS12475	COG1317	bacterial-type flagellum organization
FED51_RS12480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FED51_RS12485	COG1766	The M ring may be actively involved in energy transduction
FED51_RS12490	COG1677	Flagellar hook-basal body complex protein FliE
FED51_RS12495	COG1558	bacterial-type flagellum-dependent cell motility
FED51_RS12500	COG1815	bacterial-type flagellum-dependent cell motility
FED51_RS12510	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FED51_RS12515	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FED51_RS12520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FED51_RS12525	COG4974	Belongs to the 'phage' integrase family
FED51_RS12530	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FED51_RS12535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FED51_RS12540	COG0758	DNA mediated transformation
FED51_RS12545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FED51_RS12550	COG0045	succinate-CoA ligase (ADP-forming) activity
FED51_RS12560	COG2257	FlhB HrpN YscU SpaS Family
FED51_RS12570	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FED51_RS12580	COG0335	large ribosomal subunit rRNA binding
FED51_RS12585	COG0336	Belongs to the RNA methyltransferase TrmD family
FED51_RS12590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FED51_RS12600	COG1837	Belongs to the UPF0109 family
FED51_RS12605	COG0228	four-way junction DNA binding
FED51_RS12610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FED51_RS12615	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FED51_RS12620	COG0552	protein localization to endoplasmic reticulum
FED51_RS12625	COG1196	nuclear chromosome segregation
FED51_RS12630	COG4840	Belongs to the UPF0435 family
FED51_RS12635	COG0571	ribonuclease III activity
FED51_RS12640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FED51_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS12650	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FED51_RS12655	COG0416	fatty acid biosynthetic process
FED51_RS12660	COG1349	DNA-binding transcription factor activity
FED51_RS12665	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FED51_RS12670	COG1760	l-serine dehydratase
FED51_RS12675	COG1760	l-serine dehydratase
FED51_RS12680	COG1461	Dihydroxyacetone kinase
FED51_RS12685	COG1302	Protein conserved in bacteria
FED51_RS12690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FED51_RS12700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FED51_RS12705	COG1162	GTPase activity
FED51_RS12715	COG2815	serine threonine protein kinase
FED51_RS12715	COG0515	serine threonine protein kinase
FED51_RS12720	COG0631	protein serine/threonine phosphatase activity
FED51_RS12725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FED51_RS12730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FED51_RS12730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FED51_RS12735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FED51_RS12740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FED51_RS12745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FED51_RS12750	COG1758	RNA polymerase activity
FED51_RS12755	COG0194	GDP metabolic process
FED51_RS12760	COG2052	Domain of unknown function (DUF370)
FED51_RS12765	COG1561	YicC-like family, N-terminal region
FED51_RS12770	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FED51_RS12785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FED51_RS12790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FED51_RS12795	COG2223	nitrite transmembrane transporter activity
FED51_RS12800	COG5609	conserved protein (DUF2294)
FED51_RS12810	COG2226	methyltransferase
FED51_RS12815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FED51_RS12820	COG0284	orotidine-5'-phosphate decarboxylase activity
FED51_RS12825	COG0167	dihydroorotate dehydrogenase activity
FED51_RS12830	COG0543	2 iron, 2 sulfur cluster binding
FED51_RS12835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FED51_RS12840	COG0505	Belongs to the CarA family
FED51_RS12845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FED51_RS12850	COG0540	Belongs to the ATCase OTCase family
FED51_RS12855	COG2233	PERMEase
FED51_RS12860	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FED51_RS12865	COG0564	pseudouridine synthase activity
FED51_RS12870	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FED51_RS12875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FED51_RS12885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FED51_RS12890	COG3599	regulation of cell shape
FED51_RS12895	COG2302	S4 RNA-binding domain
FED51_RS12900	COG0762	integral membrane protein
FED51_RS12905	COG1799	cell septum assembly
FED51_RS12910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FED51_RS12915	COG1496	oxidoreductase activity
FED51_RS12920	COG1873	PFAM PRC-barrel domain
FED51_RS12925	COG0861	Integral membrane protein TerC family
FED51_RS12930	COG1191	sigma factor activity
FED51_RS12935	COG1191	sigma factor activity
FED51_RS12950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FED51_RS12955	COG0849	cell division
FED51_RS12960	COG3856	small basic protein
FED51_RS12965	COG3879	Bacterial protein of unknown function (DUF881)
FED51_RS12970	COG3879	Bacterial protein of unknown function (DUF881)
FED51_RS12975	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FED51_RS12980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FED51_RS12985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FED51_RS12995	COG0772	Belongs to the SEDS family
FED51_RS13000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FED51_RS13005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FED51_RS13010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FED51_RS13015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FED51_RS13020	COG0768	penicillin binding
FED51_RS13025	COG0768	penicillin binding
FED51_RS13030	COG4839	cell division protein FtsL
FED51_RS13035	COG0275	rRNA processing
FED51_RS13040	COG2001	Belongs to the MraZ family
FED51_RS13045	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FED51_RS13055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FED51_RS13060	COG0454	-acetyltransferase
FED51_RS13070	COG1024	Enoyl-CoA hydratase
FED51_RS13075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FED51_RS13080	COG1399	metal-binding, possibly nucleic acid-binding protein
FED51_RS13085	COG1323	Belongs to the UPF0348 family
FED51_RS13090	COG3480	Lon protease (S16) C-terminal proteolytic domain
FED51_RS13095	COG1752	Esterase of the alpha-beta hydrolase superfamily
FED51_RS13100	COG3314	Sporulation integral membrane protein YlbJ
FED51_RS13105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FED51_RS13110	COG0742	ribosomal rna small subunit methyltransferase
FED51_RS13120	COG2814	Major facilitator Superfamily
FED51_RS13130	COG4471	UPF0298 protein
FED51_RS13140	COG3679	Belongs to the UPF0342 family
FED51_RS13145	COG4294	response to UV
FED51_RS13180	COG2340	Cysteine-rich secretory protein family
FED51_RS13185	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FED51_RS13195	COG0628	permease
FED51_RS13205	COG2322	membrane
FED51_RS13210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FED51_RS13215	COG1845	cytochrome c oxidase, subunit III
FED51_RS13220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FED51_RS13225	COG2010	Cytochrome c
FED51_RS13225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FED51_RS13230	COG0109	protoheme IX farnesyltransferase activity
FED51_RS13235	COG1612	heme a metabolic process
FED51_RS13265	COG0076	glutamate decarboxylase activity
FED51_RS13275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FED51_RS13280	COG4838	Belongs to the UPF0358 family
FED51_RS13285	COG2066	Belongs to the glutaminase family
FED51_RS13290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FED51_RS13295	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FED51_RS13305	COG4896	Protein conserved in bacteria
FED51_RS13315	COG1217	gtp-binding protein TYPA
FED51_RS13330	COG2084	Dehydrogenase
FED51_RS13335	COG0483	inositol monophosphate 1-phosphatase activity
FED51_RS13345	COG4493	Belongs to the UPF0637 family
FED51_RS13350	COG4476	Belongs to the UPF0223 family
FED51_RS13360	COG1982	Orn Lys Arg decarboxylase major
FED51_RS13380	COG4129	membrane
FED51_RS13385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FED51_RS13395	COG1725	Transcriptional regulator
FED51_RS13400	COG1131	(ABC) transporter
FED51_RS13420	COG0508	dehydrogenase complex catalyzes the overall conversion of
FED51_RS13425	COG0022	dehydrogenase e1 component
FED51_RS13445	COG0242	peptide deformylase activity
FED51_RS13450	COG0561	phosphatase activity
FED51_RS13455	COG5503	Protein of unknown function (DUF1447)
FED51_RS13460	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FED51_RS13465	COG0569	domain protein
FED51_RS13470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FED51_RS13475	COG0450	alkyl hydroperoxide reductase
FED51_RS13480	COG0668	transmembrane transport
FED51_RS13495	COG1473	amidohydrolase
FED51_RS13500	COG2171	N-acyltransferase activity
FED51_RS13510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FED51_RS13510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FED51_RS13515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FED51_RS13515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FED51_RS13520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FED51_RS13525	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FED51_RS13530	COG1737	Transcriptional regulator
FED51_RS13540	COG2224	Isocitrate lyase
FED51_RS13545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FED51_RS13550	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FED51_RS13555	COG1116	anion transmembrane transporter activity
FED51_RS13560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FED51_RS13565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FED51_RS13570	COG0668	transmembrane transport
FED51_RS13600	COG0438	transferase activity, transferring glycosyl groups
FED51_RS13610	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FED51_RS13615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FED51_RS13625	COG0561	phosphatase activity
FED51_RS13635	COG2271	Major facilitator Superfamily
FED51_RS13640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FED51_RS13645	COG0501	Belongs to the peptidase M48B family
FED51_RS13650	COG0673	inositol 2-dehydrogenase activity
FED51_RS13665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FED51_RS13670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FED51_RS13685	COG0583	DNA-binding transcription factor activity
FED51_RS13690	COG1115	amino acid carrier protein
FED51_RS13695	COG0784	Response regulator, receiver
FED51_RS13700	COG4191	Histidine kinase
FED51_RS13705	COG2066	Belongs to the glutaminase family
FED51_RS13710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FED51_RS13715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FED51_RS13720	COG0662	Cupin 2, conserved barrel domain protein
FED51_RS13735	COG3250	beta-galactosidase activity
FED51_RS13755	COG2972	Histidine kinase
FED51_RS13760	COG2207	Transcriptional regulator
FED51_RS13760	COG4753	response regulator
FED51_RS13765	COG0247	lactate metabolic process
FED51_RS13770	COG0277	FAD linked oxidase domain protein
FED51_RS13775	COG3835	regulator
FED51_RS13790	COG4282	regulation of fungal-type cell wall biogenesis
FED51_RS13810	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS13825	COG0506	proline dehydrogenase activity
FED51_RS13830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FED51_RS13845	COG1742	UPF0060 membrane protein
FED51_RS13860	COG0697	spore germination
FED51_RS13865	COG2249	NAD(P)H dehydrogenase (quinone) activity
FED51_RS13870	COG2211	Major facilitator Superfamily
FED51_RS13875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FED51_RS13880	COG4565	transcriptional regulatory protein
FED51_RS13885	COG3290	protein histidine kinase activity
FED51_RS13890	COG0582	viral genome integration into host DNA
FED51_RS13975	COG0747	negative chemotaxis
FED51_RS13985	COG1070	Carbohydrate kinase
FED51_RS13990	COG2115	Belongs to the xylose isomerase family
FED51_RS13995	COG1940	carbohydrate kinase activity
FED51_RS14005	COG0803	Belongs to the bacterial solute-binding protein 9 family
FED51_RS14005	COG3443	Belongs to the bacterial solute-binding protein 9 family
FED51_RS14010	COG0508	dehydrogenase complex catalyzes the overall conversion of
FED51_RS14015	COG0022	dehydrogenase e1 component
FED51_RS14020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FED51_RS14025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FED51_RS14030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FED51_RS14035	COG3290	protein histidine kinase activity
FED51_RS14035	COG3829	transcription factor binding
FED51_RS14050	COG0463	Glycosyl transferase, family 2
FED51_RS14070	COG0745	RESPONSE REGULATOR receiver
FED51_RS14075	COG0750	zinc metalloprotease
FED51_RS14080	COG0497	DNA recombination
FED51_RS14085	COG1438	arginine binding
FED51_RS14090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FED51_RS14095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FED51_RS14105	COG0142	geranyltranstransferase activity
FED51_RS14110	COG1722	exodeoxyribonuclease VII activity
FED51_RS14115	COG1570	exodeoxyribonuclease VII activity
FED51_RS14120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FED51_RS14125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FED51_RS14130	COG1302	Protein conserved in bacteria
FED51_RS14135	COG0439	Biotin carboxylase
FED51_RS14140	COG0511	ligase activity, forming carbon-carbon bonds
FED51_RS14185	COG3854	ATPases associated with a variety of cellular activities
FED51_RS14195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FED51_RS14200	COG0006	proline dipeptidase activity
FED51_RS14205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FED51_RS14215	COG3872	metal-dependent enzyme
FED51_RS14225	COG1752	Esterase of the alpha-beta hydrolase superfamily
FED51_RS14235	COG1321	iron dependent repressor
FED51_RS14240	COG1533	DNA photolyase activity
FED51_RS14260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FED51_RS14270	COG0095	Lipoate-protein ligase
FED51_RS14275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FED51_RS14280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FED51_RS14285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FED51_RS14290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FED51_RS14295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FED51_RS14315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FED51_RS14345	COG4970	Tfp pilus assembly protein FimT
FED51_RS14350	COG4537	Required for transformation and DNA binding
FED51_RS14355	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FED51_RS14405	COG0386	Belongs to the glutathione peroxidase family
FED51_RS14410	COG1459	type II secretion system
FED51_RS14415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FED51_RS14430	COG0210	DNA helicase
FED51_RS14435	COG1418	mRNA catabolic process
FED51_RS14470	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FED51_RS14475	COG0475	glutathione-regulated potassium exporter activity
FED51_RS14475	COG0589	response to stress
FED51_RS14480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FED51_RS14490	COG0564	pseudouridine synthase activity
FED51_RS14495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FED51_RS14500	COG2357	RelA SpoT domain protein
FED51_RS14515	COG0741	lytic transglycosylase activity
FED51_RS14525	COG0243	molybdopterin cofactor binding
FED51_RS14530	COG2346	COG2346, Truncated hemoglobins
FED51_RS14535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FED51_RS14540	COG1164	Oligoendopeptidase f
FED51_RS14545	COG4469	Competence protein
FED51_RS14550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FED51_RS14560	COG4862	establishment of competence for transformation
FED51_RS14565	COG0861	Integral membrane protein TerC family
FED51_RS14570	COG1393	Belongs to the ArsC family
FED51_RS14580	COG0456	acetyltransferase
FED51_RS14590	COG1272	protein, Hemolysin III
FED51_RS14595	COG1418	mRNA catabolic process
FED51_RS14605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FED51_RS14615	COG0180	Tryptophanyl-tRNA synthetase
FED51_RS14630	COG5504	Zn-dependent protease
FED51_RS14635	COG1072	(Pantothenic acid kinase))
FED51_RS14650	COG1686	Belongs to the peptidase S11 family
FED51_RS14655	COG2340	Cysteine-rich secretory protein family
FED51_RS14660	COG3773	Cell wall hydrolase
FED51_RS14670	COG0617	tRNA 3'-terminal CCA addition
FED51_RS14675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FED51_RS14680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FED51_RS14700	COG2226	methyltransferase
FED51_RS14710	COG1744	ABC transporter substrate-binding protein PnrA-like
FED51_RS14720	COG2267	carboxylic ester hydrolase activity
FED51_RS14730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FED51_RS14735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FED51_RS14740	COG0505	Belongs to the CarA family
FED51_RS14745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FED51_RS14750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FED51_RS14755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FED51_RS14760	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FED51_RS14770	COG0366	Alpha amylase catalytic
FED51_RS14775	COG1999	signal sequence binding
FED51_RS14780	COG3336	cytochrome c oxidase
FED51_RS14785	COG0561	phosphatase activity
FED51_RS14800	COG1396	sequence-specific DNA binding
FED51_RS14805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FED51_RS14820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FED51_RS14840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FED51_RS14845	COG1073	alpha beta
FED51_RS14860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FED51_RS14865	COG0628	permease
FED51_RS14870	COG1609	Transcriptional regulator
FED51_RS14875	COG3833	ABC-type maltose transport systems, permease component
FED51_RS14880	COG1175	transmembrane transport
FED51_RS14885	COG2182	Extracellular solute-binding protein
FED51_RS14905	COG3480	Lon protease (S16) C-terminal proteolytic domain
FED51_RS14910	COG2270	Major facilitator Superfamily
FED51_RS14920	COG1280	lysine exporter protein (LysE YggA)
FED51_RS14930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FED51_RS14940	COG0534	Mate efflux family protein
FED51_RS14945	COG2358	TRAP transporter, solute receptor (TAXI family
FED51_RS14965	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FED51_RS14970	COG1509	lysine 2,3-aminomutase activity
FED51_RS14990	COG2358	TRAP transporter, solute receptor (TAXI family
FED51_RS14995	COG2204	response regulator
FED51_RS15000	COG3852	Histidine kinase
FED51_RS15015	COG0778	Nitroreductase
FED51_RS15020	COG1703	isobutyryl-CoA mutase activity
FED51_RS15025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FED51_RS15025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FED51_RS15030	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FED51_RS15035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FED51_RS15040	COG1309	transcriptional regulator
FED51_RS15065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FED51_RS15080	COG2201	protein-glutamate methylesterase activity
FED51_RS15085	COG0835	chemotaxis
FED51_RS15090	COG0643	Histidine kinase
FED51_RS15090	COG2198	Histidine kinase
FED51_RS15095	COG5001	Diguanylate cyclase
FED51_RS15095	COG3300	MHYT domain
FED51_RS15110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FED51_RS15115	COG3639	organic phosphonate transmembrane transporter activity
FED51_RS15120	COG3639	organic phosphonate transmembrane transporter activity
FED51_RS15130	COG1074	ATP-dependent DNA helicase activity
FED51_RS15135	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FED51_RS15155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FED51_RS15160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FED51_RS15185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FED51_RS15190	COG0581	inorganic phosphate transmembrane transporter activity
FED51_RS15195	COG0573	inorganic phosphate transmembrane transporter activity
FED51_RS15200	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FED51_RS15205	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS15210	COG0640	Transcriptional regulator
FED51_RS15225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FED51_RS15230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FED51_RS15235	COG0640	Transcriptional regulator
FED51_RS15240	COG0110	maltose O-acetyltransferase activity
FED51_RS15245	COG1234	tRNA 3'-trailer cleavage
FED51_RS15265	COG4948	Mandelate Racemase Muconate Lactonizing
FED51_RS15275	COG1228	amidohydrolase
FED51_RS15280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FED51_RS15285	COG2868	ribosomal protein
FED51_RS15290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FED51_RS15300	COG1530	ribonuclease E activity
FED51_RS15305	COG1994	Peptidase M50
FED51_RS15310	COG0739	heme binding
FED51_RS15315	COG0746	molybdenum cofactor guanylyltransferase activity
FED51_RS15325	COG0314	molybdopterin synthase activity
FED51_RS15330	COG1763	Mo-molybdopterin cofactor biosynthetic process
FED51_RS15335	COG0303	'Molybdopterin
FED51_RS15340	COG0521	Mo-molybdopterin cofactor biosynthetic process
FED51_RS15345	COG0315	cyclic pyranopterin monophosphate synthase activity
FED51_RS15355	COG0693	protein deglycase activity
FED51_RS15360	COG0747	negative chemotaxis
FED51_RS15370	COG2894	cell division
FED51_RS15375	COG0850	regulation of cytokinetic process
FED51_RS15380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FED51_RS15385	COG1792	Involved in formation and maintenance of cell shape
FED51_RS15390	COG1077	Cell shape determining protein MreB Mrl
FED51_RS15395	COG2003	Belongs to the UPF0758 family
FED51_RS15400	COG0424	maF-like protein
FED51_RS15410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FED51_RS15415	COG3706	GGDEF domain
FED51_RS15420	COG0285	dihydrofolate synthase activity
FED51_RS15425	COG0525	valine-tRNA ligase activity
FED51_RS15445	COG1388	LysM domain
FED51_RS15445	COG1388	LysM domain
FED51_RS15450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FED51_RS15455	COG0113	porphobilinogen synthase activity
FED51_RS15460	COG1587	Uroporphyrinogen-III synthase
FED51_RS15465	COG0181	hydroxymethylbilane synthase activity
FED51_RS15470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FED51_RS15475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FED51_RS15480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FED51_RS15485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FED51_RS15490	COG1067	ATP-dependent peptidase activity
FED51_RS15490	COG0470	DNA polymerase III
FED51_RS15495	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FED51_RS15500	COG0544	peptidyl-prolyl cis-trans isomerase activity
FED51_RS15505	COG1477	protein flavinylation
FED51_RS15505	COG0457	Tetratricopeptide repeat
FED51_RS15510	COG0066	3-isopropylmalate dehydratase activity
FED51_RS15515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FED51_RS15520	COG0473	3-isopropylmalate dehydrogenase activity
FED51_RS15525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FED51_RS15530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FED51_RS15535	COG0440	acetolactate synthase activity
FED51_RS15540	COG0028	Belongs to the TPP enzyme family
FED51_RS15545	COG0129	dihydroxy-acid dehydratase activity
FED51_RS15575	COG0622	Phosphoesterase
FED51_RS15580	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FED51_RS15585	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FED51_RS15590	COG5401	PFAM Sporulation and spore germination
FED51_RS15605	COG1846	Transcriptional regulator
FED51_RS15610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FED51_RS15615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FED51_RS15620	COG2197	response regulator
FED51_RS15640	COG2808	Putative FMN-binding domain
FED51_RS15645	COG0456	acetyltransferase
FED51_RS15650	COG1846	Transcriptional regulator
FED51_RS15675	COG0251	oxidation-reduction process
FED51_RS15690	COG3739	integral membrane protein
FED51_RS15705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FED51_RS15710	COG1053	succinate dehydrogenase
FED51_RS15715	COG2009	succinate dehydrogenase
FED51_RS15720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FED51_RS15725	COG1719	4-vinyl reductase, 4VR
FED51_RS15740	COG0322	excinuclease ABC activity
FED51_RS15745	COG3118	belongs to the thioredoxin family
FED51_RS15750	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FED51_RS15755	COG2086	electron transfer activity
FED51_RS15760	COG1024	Enoyl-CoA hydratase
FED51_RS15765	COG1309	transcriptional regulator
FED51_RS15770	COG0318	PFAM AMP-dependent synthetase and ligase
FED51_RS15775	COG0318	PFAM AMP-dependent synthetase and ligase
FED51_RS15780	COG3766	membrane
FED51_RS15785	COG1193	negative regulation of DNA recombination
FED51_RS15790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FED51_RS15790	COG1796	DNA polymerase
FED51_RS15795	COG1286	toxin biosynthetic process
FED51_RS15800	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FED51_RS15805	COG1280	lysine exporter protein (LysE YggA)
FED51_RS15810	COG3403	YqcI/YcgG family
FED51_RS15815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FED51_RS15815	COG0072	phenylalanine-tRNA ligase activity
FED51_RS15820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FED51_RS15825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FED51_RS15840	COG2318	DinB family
FED51_RS15850	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FED51_RS15860	COG0740	serine-type endopeptidase activity
FED51_RS15875	COG0577	efflux transmembrane transporter activity
FED51_RS15880	COG1136	(ABC) transporter
FED51_RS15900	COG1363	Peptidase, m42
FED51_RS15920	COG3326	Membrane
FED51_RS15925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FED51_RS15930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FED51_RS15935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FED51_RS15940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FED51_RS15950	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FED51_RS15955	COG1484	DNA-dependent DNA replication
FED51_RS15960	COG3611	Membrane attachment protein
FED51_RS15965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FED51_RS15975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FED51_RS15980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FED51_RS15985	COG0237	dephospho-CoA kinase activity
FED51_RS15990	COG1971	Probably functions as a manganese efflux pump
FED51_RS15995	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FED51_RS16000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FED51_RS16000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FED51_RS16005	COG0330	HflC and HflK could
FED51_RS16010	COG0330	HflC and HflK could
FED51_RS16015	COG5002	protein histidine kinase activity
FED51_RS16020	COG0745	RESPONSE REGULATOR receiver
FED51_RS16025	COG0039	L-malate dehydrogenase activity
FED51_RS16030	COG0538	isocitrate dehydrogenase activity
FED51_RS16035	COG0372	Belongs to the citrate synthase family
FED51_RS16040	COG2707	UPF0756 membrane protein
FED51_RS16045	COG3030	protein affecting phage T7 exclusion by the F plasmid
FED51_RS16055	COG0205	6-phosphofructokinase activity
FED51_RS16060	COG0825	malonyl-CoA metabolic process
FED51_RS16065	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FED51_RS16070	COG2186	Transcriptional regulator
FED51_RS16075	COG0281	malic enzyme
FED51_RS16080	COG0587	DNA-directed DNA polymerase activity
FED51_RS16100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FED51_RS16110	COG4109	DRTGG domain
FED51_RS16125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FED51_RS16130	COG0006	proline dipeptidase activity
FED51_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS16150	COG0589	response to stress
FED51_RS16165	COG0165	Argininosuccinate lyase
FED51_RS16170	COG0137	argininosuccinate synthase activity
FED51_RS16185	COG2217	Heavy metal translocating P-type atpase
FED51_RS16190	COG3481	metal-dependent phosphohydrolase, HD sub domain
FED51_RS16195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FED51_RS16200	COG0827	DNA restriction-modification system
FED51_RS16205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FED51_RS16210	COG3874	Sporulation protein YtfJ
FED51_RS16220	COG1714	RDD family
FED51_RS16225	COG0616	signal peptide processing
FED51_RS16230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FED51_RS16235	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FED51_RS16240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FED51_RS16250	COG0301	tRNA thio-modification
FED51_RS16255	COG1104	cysteine desulfurase activity
FED51_RS16260	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FED51_RS16265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FED51_RS16270	COG1309	transcriptional regulator
FED51_RS16275	COG1956	GAF domain-containing protein
FED51_RS16280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FED51_RS16315	COG1595	DNA-templated transcription, initiation
FED51_RS16360	COG2239	Acts as a magnesium transporter
FED51_RS16365	COG1285	pathogenesis
FED51_RS16375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FED51_RS16390	COG1609	Transcriptional regulator
FED51_RS16405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FED51_RS16410	COG0454	-acetyltransferase
FED51_RS16415	COG0517	IMP dehydrogenase activity
FED51_RS16420	COG0123	including yeast histone deacetylase and acetoin utilization protein
FED51_RS16425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FED51_RS16435	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FED51_RS16440	COG1609	Transcriptional regulator
FED51_RS16445	COG1605	Chorismate mutase
FED51_RS16445	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FED51_RS16450	COG0849	cell division
FED51_RS16455	COG4980	gas vesicle protein
FED51_RS16465	COG2309	aminopeptidase activity
FED51_RS16470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FED51_RS16480	COG1674	ftsk spoiiie
FED51_RS16485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FED51_RS16490	COG4848	Belongs to the UPF0354 family
FED51_RS16495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FED51_RS16510	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FED51_RS16515	COG1363	Peptidase, m42
FED51_RS16520	COG5584	Small secreted protein
FED51_RS16525	COG0217	transcriptional regulatory protein
FED51_RS16530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FED51_RS16535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FED51_RS16545	COG0510	thiamine kinase activity
FED51_RS16550	COG1523	belongs to the glycosyl hydrolase 13 family
FED51_RS16555	COG0788	formyltetrahydrofolate deformylase activity
FED51_RS16570	COG1346	cytolysis
FED51_RS16575	COG1380	Effector of murein hydrolase LrgA
FED51_RS16585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FED51_RS16590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FED51_RS16595	COG1349	DNA-binding transcription factor activity
FED51_RS16600	COG1187	pseudouridine synthase activity
FED51_RS16610	COG0772	Belongs to the SEDS family
FED51_RS16615	COG0772	Belongs to the SEDS family
FED51_RS16620	COG2244	polysaccharide biosynthetic process
FED51_RS16630	COG2081	HI0933 family
FED51_RS16640	COG0495	leucyl-tRNA aminoacylation
FED51_RS16650	COG2814	Major facilitator Superfamily
FED51_RS16655	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FED51_RS16660	COG1242	4 iron, 4 sulfur cluster binding
FED51_RS16665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FED51_RS16670	COG0288	reversible hydration of carbon dioxide
FED51_RS16680	COG2267	carboxylic ester hydrolase activity
FED51_RS16685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FED51_RS16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS16705	COG1120	ATPase activity
FED51_RS16710	COG2329	Antibiotic biosynthesis monooxygenase
FED51_RS16715	COG4509	Sortase family
FED51_RS16735	COG5386	Cell surface protein
FED51_RS16740	COG5386	Cell surface protein
FED51_RS16745	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FED51_RS16755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FED51_RS16760	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FED51_RS16765	COG1733	regulation of RNA biosynthetic process
FED51_RS16775	COG2514	catechol 2,3-dioxygenase activity
FED51_RS16780	COG1506	peptidase
FED51_RS16790	COG0494	nUDIX hydrolase
FED51_RS16795	COG2814	Major facilitator Superfamily
FED51_RS16810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FED51_RS16815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FED51_RS16825	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS16835	COG2814	Major facilitator Superfamily
FED51_RS16850	COG0431	NADPH-dependent FMN reductase
FED51_RS16855	COG3584	3D domain protein
FED51_RS16855	COG3583	domain protein
FED51_RS16865	COG2188	Transcriptional regulator
FED51_RS16870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FED51_RS16875	COG4821	SIS domain
FED51_RS16880	COG3458	cephalosporin-C deacetylase activity
FED51_RS16885	COG0471	metal ion transport
FED51_RS16890	COG4149	molybdate abc transporter
FED51_RS16895	COG0725	ABC transporter, periplasmic molybdate-binding protein
FED51_RS16920	COG1999	signal sequence binding
FED51_RS16945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FED51_RS16960	COG0166	Belongs to the GPI family
FED51_RS16965	COG1979	alcohol dehydrogenase
FED51_RS16970	COG2155	Conserved Protein
FED51_RS16985	COG1098	S1 RNA binding domain
FED51_RS16995	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FED51_RS17000	COG0436	Aminotransferase
FED51_RS17005	COG1522	sequence-specific DNA binding
FED51_RS17010	COG5506	Protein of unknown function (DUF1694)
FED51_RS17015	COG1854	S-ribosylhomocysteine lyase activity
FED51_RS17025	COG1295	ribonuclease BN
FED51_RS17030	COG0776	regulation of translation
FED51_RS17040	COG1714	RDD family
FED51_RS17050	COG1268	BioY protein
FED51_RS17055	COG2056	Na+-H+ antiporter family
FED51_RS17065	COG0457	Tetratricopeptide repeat
FED51_RS17140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FED51_RS17145	COG1088	dTDP-glucose 4,6-dehydratase activity
FED51_RS17150	COG1091	dTDP-4-dehydrorhamnose reductase activity
FED51_RS17155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FED51_RS17185	COG0613	PHP domain protein
FED51_RS17190	COG0463	Glycosyl transferase, family 2
FED51_RS17220	COG1216	Glycosyl transferase, family 2
FED51_RS17240	COG1216	Glycosyl transferase, family 2
FED51_RS17255	COG1086	Polysaccharide biosynthesis protein
FED51_RS17270	COG0471	metal ion transport
FED51_RS17270	COG3273	potassium ion transport
FED51_RS17275	COG0529	Catalyzes the synthesis of activated sulfate
FED51_RS17285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FED51_RS17295	COG0768	penicillin binding
FED51_RS17300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FED51_RS17305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FED51_RS17310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FED51_RS17315	COG2376	Dihydroxyacetone kinase
FED51_RS17320	COG1309	transcriptional regulator
FED51_RS17325	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FED51_RS17330	COG1461	Dihydroxyacetone kinase
FED51_RS17335	COG2376	Dihydroxyacetone kinase
FED51_RS17340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FED51_RS17350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FED51_RS17355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FED51_RS17360	COG3584	3D domain protein
FED51_RS17375	COG1252	NADH dehydrogenase
FED51_RS17380	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS17385	COG0316	Belongs to the HesB IscA family
FED51_RS17395	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FED51_RS17400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FED51_RS17410	COG4844	belongs to the
FED51_RS17415	COG1252	NADH dehydrogenase
FED51_RS17420	COG4837	Protein of unknown function (DUF1462)
FED51_RS17425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FED51_RS17440	COG0083	homoserine kinase activity
FED51_RS17445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FED51_RS17450	COG0460	homoserine dehydrogenase
FED51_RS17455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FED51_RS17460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FED51_RS17465	COG2205	protein histidine kinase activity
FED51_RS17470	COG0745	RESPONSE REGULATOR receiver
FED51_RS17475	COG2311	Membrane
FED51_RS17480	COG0647	UMP catabolic process
FED51_RS17490	COG2445	Protein of unknown function DUF86
FED51_RS17495	COG1494	fructose-1,6-bisphosphatase
FED51_RS17505	COG4470	Protein conserved in bacteria
FED51_RS17515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FED51_RS17520	COG0739	heme binding
FED51_RS17535	COG0733	neurotransmitter:sodium symporter activity
FED51_RS17540	COG4214	carbohydrate transport
FED51_RS17545	COG1129	ABC transporter
FED51_RS17550	COG4213	ABC transporter substrate-binding protein
FED51_RS17555	COG2197	response regulator
FED51_RS17560	COG2972	Histidine kinase
FED51_RS17570	COG1757	Na H antiporter
FED51_RS17575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FED51_RS17580	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FED51_RS17585	COG3377	Domain of unknown function (DUF1805)
FED51_RS17590	COG0737	Belongs to the 5'-nucleotidase family
FED51_RS17595	COG0730	response to heat
FED51_RS17600	COG1801	Protein of unknown function DUF72
FED51_RS17610	COG0789	Transcriptional regulator
FED51_RS17650	COG0719	Fe-S assembly protein
FED51_RS17655	COG0822	iron-sulfur transferase activity
FED51_RS17660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FED51_RS17665	COG0719	Fe-S assembly protein
FED51_RS17670	COG0396	ATPase activity
FED51_RS17680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FED51_RS17690	COG4512	PFAM Accessory gene regulator B
FED51_RS17705	COG1464	Belongs to the NlpA lipoprotein family
FED51_RS17710	COG2011	ABC-type metal ion transport system permease component
FED51_RS17715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FED51_RS17735	COG0509	glycine decarboxylation via glycine cleavage system
FED51_RS17740	COG1393	Belongs to the ArsC family
FED51_RS17745	COG1960	acyl-CoA dehydrogenase activity
FED51_RS17750	COG0183	Belongs to the thiolase family
FED51_RS17755	COG1024	Enoyl-CoA hydratase
FED51_RS17755	COG1250	3-hydroxyacyl-CoA dehydrogenase
FED51_RS17765	COG5577	PFAM Coat F domain
FED51_RS17780	COG1131	(ABC) transporter
FED51_RS17795	COG0432	Pfam Uncharacterised protein family UPF0047
FED51_RS17800	COG2268	Band 7 protein
FED51_RS17830	COG1136	(ABC) transporter
FED51_RS17835	COG2207	Transcriptional regulator
FED51_RS17965	COG5484	DNA packaging
FED51_RS18055	COG1396	sequence-specific DNA binding
FED51_RS18075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FED51_RS18080	COG0557	exoribonuclease II activity
FED51_RS18085	COG1647	Serine aminopeptidase, S33
FED51_RS18090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FED51_RS18095	COG0148	phosphopyruvate hydratase activity
FED51_RS18100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FED51_RS18105	COG0149	triose-phosphate isomerase activity
FED51_RS18110	COG0126	phosphoglycerate kinase activity
FED51_RS18115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FED51_RS18130	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FED51_RS18135	COG0740	serine-type endopeptidase activity
FED51_RS18145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FED51_RS18150	COG1481	regulation of sporulation
FED51_RS18155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FED51_RS18160	COG1660	Displays ATPase and GTPase activities
FED51_RS18165	COG1051	belongs to the nudix hydrolase family
FED51_RS18175	COG0492	ferredoxin-NADP+ reductase activity
FED51_RS18180	COG0457	Tetratricopeptide repeat
FED51_RS18190	COG1263	PTS System
FED51_RS18190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FED51_RS18195	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FED51_RS18200	COG1737	Transcriptional regulator
FED51_RS18205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FED51_RS18205	COG0140	phosphoribosyl-ATP diphosphatase activity
FED51_RS18210	COG0107	imidazoleglycerol-phosphate synthase activity
FED51_RS18215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FED51_RS18220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FED51_RS18225	COG0131	Imidazoleglycerol-phosphate dehydratase
FED51_RS18230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FED51_RS18235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FED51_RS18240	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FED51_RS18245	COG0110	maltose O-acetyltransferase activity
FED51_RS18250	COG0546	phosphoglycolate phosphatase activity
FED51_RS18255	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FED51_RS18260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FED51_RS18265	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FED51_RS18270	COG1950	PFAM Membrane protein of
FED51_RS18275	COG1983	PspC domain protein
FED51_RS18280	COG3595	metallopeptidase activity
FED51_RS18285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FED51_RS18290	COG0556	nucleotide-excision repair
FED51_RS18295	COG3764	Sortase (surface protein transpeptidase)
FED51_RS18305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FED51_RS18310	COG3409	Peptidoglycan-binding domain 1 protein
FED51_RS18310	COG0793	Belongs to the peptidase S41A family
FED51_RS18315	COG0739	heme binding
FED51_RS18320	COG2177	Part of the ABC transporter FtsEX involved in
FED51_RS18325	COG2884	Cell division ATP-binding protein ftsE
FED51_RS18330	COG4654	Cytochrome c, class I
FED51_RS18335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FED51_RS18345	COG0653	protein targeting
FED51_RS18355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FED51_RS18365	COG1278	Cold shock
FED51_RS18385	COG1516	flagellar protein fliS
FED51_RS18390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FED51_RS18395	COG1334	flagellar protein FlaG
FED51_RS18400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FED51_RS18405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FED51_RS18410	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FED51_RS18420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FED51_RS18425	COG4786	Flagellar basal body rod
FED51_RS18425	COG1256	bacterial-type flagellum assembly
FED51_RS18445	COG1040	competence protein
FED51_RS18450	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FED51_RS18455	COG1307	EDD domain protein, DegV family
FED51_RS18470	COG1739	Uncharacterized protein family UPF0029
FED51_RS18490	COG3708	Transcriptional regulator
FED51_RS18490	COG2207	Transcriptional regulator
FED51_RS18510	COG0601	transmembrane transport
FED51_RS18515	COG4608	Belongs to the ABC transporter superfamily
FED51_RS18525	COG1522	sequence-specific DNA binding
FED51_RS18530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FED51_RS18535	COG0601	transmembrane transport
FED51_RS18540	COG0747	negative chemotaxis
FED51_RS18545	COG4608	Belongs to the ABC transporter superfamily
FED51_RS18550	COG0444	Belongs to the ABC transporter superfamily
FED51_RS18555	COG1316	TRANSCRIPTIONal
FED51_RS18560	COG2385	sporulation resulting in formation of a cellular spore
FED51_RS18565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FED51_RS18570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FED51_RS18575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FED51_RS18580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FED51_RS18580	COG0189	ligase activity
FED51_RS18590	COG1181	Belongs to the D-alanine--D-alanine ligase family
FED51_RS18590	COG2918	glutathione biosynthetic process
FED51_RS18605	COG1215	transferase activity, transferring glycosyl groups
FED51_RS18610	COG1216	Glycosyl transferase, family 2
FED51_RS18615	COG1134	teichoic acid transport
FED51_RS18620	COG1682	transport, permease protein
FED51_RS18625	COG1215	transferase activity, transferring glycosyl groups
FED51_RS18635	COG0438	transferase activity, transferring glycosyl groups
FED51_RS18640	COG0860	N-Acetylmuramoyl-L-alanine amidase
FED51_RS18640	COG2247	cell wall binding repeat
FED51_RS18675	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FED51_RS18680	COG0732	type I restriction modification DNA specificity domain
FED51_RS18690	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FED51_RS18695	COG4464	protein tyrosine phosphatase activity
FED51_RS18700	COG0489	protein tyrosine kinase activity
FED51_RS18705	COG3944	biosynthesis protein
FED51_RS18710	COG1316	TRANSCRIPTIONal
FED51_RS18720	COG0791	NLP P60 protein
FED51_RS18720	COG1388	LysM domain
FED51_RS18725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FED51_RS18730	COG1136	(ABC) transporter
FED51_RS18735	COG0577	efflux transmembrane transporter activity
FED51_RS18755	COG3547	Transposase (IS116 IS110 IS902 family)
FED51_RS18760	COG2072	flavoprotein involved in K transport
FED51_RS18765	COG2972	Histidine kinase
FED51_RS18770	COG2207	Transcriptional regulator
FED51_RS18770	COG4753	response regulator
FED51_RS18775	COG1653	transport
FED51_RS18780	COG1175	transmembrane transport
FED51_RS18785	COG0395	ABC-type sugar transport system, permease component
FED51_RS18790	COG3507	Belongs to the glycosyl hydrolase 43 family
FED51_RS18795	COG5578	integral membrane protein
FED51_RS18800	COG2318	DinB family
FED51_RS18835	COG1609	Transcriptional regulator
FED51_RS18840	COG2311	Membrane
FED51_RS18850	COG0457	Tetratricopeptide repeat
FED51_RS18855	COG1523	belongs to the glycosyl hydrolase 13 family
FED51_RS18865	COG3328	transposase activity
FED51_RS18885	COG0584	glycerophosphoryl diester phosphodiesterase
FED51_RS18910	COG5444	nuclease activity
FED51_RS18915	COG0457	Tetratricopeptide repeat
FED51_RS18980	COG1216	Glycosyl transferase, family 2
FED51_RS18985	COG0438	transferase activity, transferring glycosyl groups
FED51_RS18995	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FED51_RS19010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FED51_RS19015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FED51_RS19020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FED51_RS19030	COG2336	PFAM SpoVT AbrB
FED51_RS19035	COG2337	Toxic component of a toxin-antitoxin (TA) module
FED51_RS19040	COG0800	Aldolase
FED51_RS19045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FED51_RS19050	COG1414	Transcriptional regulator
FED51_RS19060	COG1609	Transcriptional regulator
FED51_RS19065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FED51_RS19070	COG1869	D-ribose catabolic process
FED51_RS19075	COG1129	ABC transporter
FED51_RS19080	COG1172	Belongs to the binding-protein-dependent transport system permease family
FED51_RS19085	COG1879	ABC-type sugar transport system periplasmic component
FED51_RS19100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FED51_RS19110	COG4786	Flagellar basal body rod
FED51_RS19115	COG4786	Flagellar basal body rod
FED51_RS19120	COG1077	Cell shape determining protein MreB Mrl
FED51_RS19125	COG1609	Transcriptional regulator
FED51_RS19130	COG1199	ATP-dependent helicase activity
FED51_RS19130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FED51_RS19135	COG0617	tRNA 3'-terminal CCA addition
FED51_RS19135	COG0517	IMP dehydrogenase activity
FED51_RS19135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FED51_RS19140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FED51_RS19150	COG0739	heme binding
FED51_RS19160	COG2385	sporulation resulting in formation of a cellular spore
FED51_RS19165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FED51_RS19175	COG4836	Membrane
FED51_RS19180	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FED51_RS19185	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FED51_RS19190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FED51_RS19195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FED51_RS19200	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FED51_RS19205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FED51_RS19210	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FED51_RS19215	COG0356	it plays a direct role in the translocation of protons across the membrane
FED51_RS19230	COG1404	Belongs to the peptidase S8 family
FED51_RS19235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FED51_RS19240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FED51_RS19245	COG4475	Protein of unknown function (DUF436)
FED51_RS19250	COG0698	ribose 5-phosphate isomerase
FED51_RS19255	COG0840	transmembrane signaling receptor activity
FED51_RS19265	COG1971	Probably functions as a manganese efflux pump
FED51_RS19270	COG0009	L-threonylcarbamoyladenylate synthase
FED51_RS19290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FED51_RS19300	COG1335	isochorismatase
FED51_RS19310	COG1435	thymidine kinase activity
FED51_RS19315	COG0254	rRNA binding
FED51_RS19320	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FED51_RS19325	COG1494	fructose-1,6-bisphosphatase
FED51_RS19330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FED51_RS19335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FED51_RS19345	COG0191	fructose-bisphosphate aldolase activity
FED51_RS19350	COG2204	response regulator
FED51_RS19360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS19365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FED51_RS19370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FED51_RS19380	COG0504	CTP synthase activity
FED51_RS19385	COG3343	RNA polymerase activity
FED51_RS19395	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FED51_RS19395	COG1703	isobutyryl-CoA mutase activity
FED51_RS19395	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FED51_RS19405	COG1960	acyl-CoA dehydrogenase activity
FED51_RS19410	COG1960	acyl-CoA dehydrogenase activity
FED51_RS19415	COG1250	3-hydroxyacyl-CoA dehydrogenase
FED51_RS19420	COG0183	Belongs to the thiolase family
FED51_RS19425	COG2181	nitrate reductase activity
FED51_RS19425	COG0247	lactate metabolic process
FED51_RS19430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FED51_RS19435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FED51_RS19440	COG2267	carboxylic ester hydrolase activity
FED51_RS19450	COG2839	Protein conserved in bacteria
FED51_RS19455	COG0018	arginyl-trna synthetase
FED51_RS19465	COG0010	Belongs to the arginase family
FED51_RS19470	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FED51_RS19475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FED51_RS19485	COG1942	4-Oxalocrotonate Tautomerase
FED51_RS19500	COG3465	dGTPase activity
FED51_RS19505	COG1078	dGTPase activity
FED51_RS19515	COG1301	dicarboxylic acid transport
FED51_RS19520	COG4844	belongs to the
FED51_RS19525	COG0095	Lipoate-protein ligase
FED51_RS19530	COG0280	phosphate acetyltransferase
FED51_RS19535	COG1024	Enoyl-CoA hydratase
FED51_RS19540	COG3253	May function as heme-dependent peroxidase
FED51_RS19545	COG3773	Cell wall hydrolase
FED51_RS19555	COG2363	Small membrane protein
FED51_RS19560	COG0456	acetyltransferase
FED51_RS19575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FED51_RS19585	COG0004	ammonium transporteR
FED51_RS19595	COG2368	4-hydroxyphenylacetate
FED51_RS19605	COG4565	transcriptional regulatory protein
FED51_RS19610	COG3290	protein histidine kinase activity
FED51_RS19620	COG2972	Histidine kinase
FED51_RS19625	COG4753	response regulator
FED51_RS19625	COG2207	Transcriptional regulator
FED51_RS19645	COG1175	transmembrane transport
FED51_RS19650	COG0395	ABC-type sugar transport system, permease component
FED51_RS19660	COG0656	L-ascorbic acid biosynthetic process
FED51_RS19665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FED51_RS19670	COG0246	Mannitol dehydrogenase
FED51_RS19675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FED51_RS19680	COG3711	transcriptional antiterminator
FED51_RS19685	COG2213	PTS system mannitol-specific
FED51_RS19715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FED51_RS19720	COG2234	aminopeptidase activity
FED51_RS19730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FED51_RS19745	COG2962	Rard protein
FED51_RS19760	COG0366	Alpha amylase catalytic
FED51_RS19770	COG5609	conserved protein (DUF2294)
FED51_RS19775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FED51_RS19775	COG0723	plastoquinol--plastocyanin reductase activity
FED51_RS19785	COG0028	Belongs to the TPP enzyme family
FED51_RS19800	COG5582	Belongs to the UPF0302 family
FED51_RS19805	COG1522	sequence-specific DNA binding
FED51_RS19820	COG2814	Major facilitator Superfamily
FED51_RS19835	COG2329	Antibiotic biosynthesis monooxygenase
FED51_RS19840	COG1733	regulation of RNA biosynthetic process
FED51_RS19845	COG2249	NAD(P)H dehydrogenase (quinone) activity
FED51_RS19850	COG2814	Major facilitator Superfamily
FED51_RS19855	COG5577	PFAM Coat F domain
FED51_RS19875	COG1132	(ABC) transporter
FED51_RS19890	COG1131	(ABC) transporter
FED51_RS19900	COG1028	Short-chain dehydrogenase reductase Sdr
FED51_RS19905	COG2610	gluconate transmembrane transporter activity
FED51_RS19915	COG3290	protein histidine kinase activity
FED51_RS19915	COG3829	transcription factor binding
FED51_RS19920	COG0726	polysaccharide deacetylase
FED51_RS19925	COG0840	transmembrane signaling receptor activity
FED51_RS19935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FED51_RS19940	COG0805	protein transport
FED51_RS19945	COG0156	8-amino-7-oxononanoate synthase activity
FED51_RS19950	COG0596	Alpha beta hydrolase
FED51_RS19955	COG4106	trans-aconitate 2-methyltransferase activity
FED51_RS19970	COG0745	RESPONSE REGULATOR receiver
FED51_RS19975	COG0642	Histidine kinase
FED51_RS19980	COG1136	(ABC) transporter
FED51_RS19985	COG0577	efflux transmembrane transporter activity
FED51_RS19990	COG0840	transmembrane signaling receptor activity
FED51_RS19995	COG1482	cell wall glycoprotein biosynthetic process
FED51_RS20000	COG2188	Transcriptional regulator
FED51_RS20005	COG2723	6-phospho-beta-galactosidase activity
FED51_RS20010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FED51_RS20015	COG1447	Phosphotransferase system cellobiose-specific component IIA
FED51_RS20020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FED51_RS20025	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FED51_RS20030	COG2079	MmgE PrpD family protein
FED51_RS20035	COG0372	Belongs to the citrate synthase family
FED51_RS20040	COG0583	DNA-binding transcription factor activity
FED51_RS20045	COG1115	amino acid carrier protein
FED51_RS20050	COG4989	oxidoreductase activity
FED51_RS20060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FED51_RS20090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FED51_RS20115	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FED51_RS20120	COG1329	Transcriptional regulator
FED51_RS20125	COG1620	l-lactate permease
FED51_RS20130	COG0039	L-malate dehydrogenase activity
FED51_RS20140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FED51_RS20145	COG1012	belongs to the aldehyde dehydrogenase family
FED51_RS20155	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FED51_RS20160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FED51_RS20165	COG3829	transcription factor binding
FED51_RS20170	COG1757	Na H antiporter
FED51_RS20175	COG3314	Sporulation integral membrane protein YlbJ
FED51_RS20185	COG1063	alcohol dehydrogenase
FED51_RS20205	COG1136	(ABC) transporter
FED51_RS20245	COG0579	oxidoreductase
FED51_RS20250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FED51_RS20270	COG2002	toxin-antitoxin pair type II binding
FED51_RS20285	COG4988	ABC transporter
FED51_RS20290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FED51_RS20295	COG1294	oxidase, subunit
FED51_RS20300	COG1271	oxidase subunit
FED51_RS20315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FED51_RS20330	COG1476	TRANSCRIPTIONal
FED51_RS20355	COG3645	SOS response
FED51_RS20370	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FED51_RS20445	COG0202	RNA polymerase activity
FED51_RS20525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FED51_RS20530	COG3328	transposase activity
FED51_RS20540	COG0765	amino acid transport
FED51_RS20560	COG1126	abc transporter atp-binding protein
FED51_RS20565	COG2040	homocysteine
FED51_RS20600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FED51_RS20610	COG2002	toxin-antitoxin pair type II binding
FED51_RS20625	COG3328	transposase activity
FED51_RS20715	COG0457	Tetratricopeptide repeat
FED51_RS20745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FED51_RS20750	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FED51_RS20755	COG4853	Protein conserved in bacteria
FED51_RS20760	COG4863	YycH protein
FED51_RS20765	COG5002	protein histidine kinase activity
FED51_RS20770	COG0745	RESPONSE REGULATOR receiver
FED51_RS20805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FED51_RS20810	COG0305	Participates in initiation and elongation during chromosome replication
FED51_RS20815	COG0359	binds to the 23S rRNA
FED51_RS20820	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FED51_RS20825	COG4241	membrane
FED51_RS20830	COG1115	amino acid carrier protein
FED51_RS20860	COG0582	viral genome integration into host DNA
FED51_RS20880	COG0789	Transcriptional regulator
FED51_RS20880	COG4978	Transcriptional regulator
FED51_RS20885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FED51_RS20890	COG0629	single-stranded DNA binding
FED51_RS20895	COG0360	Binds together with S18 to 16S ribosomal RNA
FED51_RS20900	COG0012	GTP binding
FED51_RS20905	COG4481	Protein conserved in bacteria
FED51_RS20910	COG3949	Membrane
FED51_RS20920	COG1811	Na channel or pump
FED51_RS20925	COG1104	cysteine desulfurase activity
FED51_RS20930	COG1475	DNA binding
FED51_RS20935	COG1192	Involved in chromosome partitioning
FED51_RS20940	COG1475	DNA binding
FED51_RS20945	COG0357	Ribosomal RNA small subunit methyltransferase G
FED51_RS20950	COG0445	tRNA wobble uridine modification
FED51_RS20955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FED51_RS20960	COG1847	R3H domain protein
FED51_RS20965	COG0706	membrane insertase activity
FED51_RS20970	COG0594	ribonuclease P activity
FED51_RS20975	COG0230	Belongs to the bacterial ribosomal protein bL34 family