locus-tag	class	description
NDR85_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NDR85_RS00010	COG0592	DNA-directed DNA polymerase activity
NDR85_RS00015	COG2501	S4 domain
NDR85_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NDR85_RS00030	COG0187	DNA topoisomerase II activity
NDR85_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NDR85_RS00070	COG0516	GMP reductase activity
NDR85_RS00070	COG0517	IMP dehydrogenase activity
NDR85_RS00075	COG1686	Belongs to the peptidase S11 family
NDR85_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NDR85_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NDR85_RS00100	COG1428	Deoxynucleoside kinase
NDR85_RS00105	COG1428	Deoxynucleoside kinase
NDR85_RS00110	COG1388	LysM domain
NDR85_RS00110	COG3858	chitin binding
NDR85_RS00115	COG1335	isochorismatase
NDR85_RS00120	COG0590	tRNA wobble adenosine to inosine editing
NDR85_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NDR85_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NDR85_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NDR85_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NDR85_RS00190	COG3853	Toxic anion resistance protein (TelA)
NDR85_RS00195	COG1982	Orn Lys Arg decarboxylase major
NDR85_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NDR85_RS00205	COG3870	Protein conserved in bacteria
NDR85_RS00210	COG1728	Protein conserved in bacteria
NDR85_RS00215	COG0470	DNA polymerase III
NDR85_RS00220	COG1774	PSP1 C-terminal conserved region
NDR85_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NDR85_RS00235	COG2827	Endonuclease containing a URI domain
NDR85_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NDR85_RS00245	COG2002	toxin-antitoxin pair type II binding
NDR85_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDR85_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDR85_RS00255	COG0084	hydrolase, TatD family'
NDR85_RS00260	COG3583	domain protein
NDR85_RS00260	COG3584	3D domain protein
NDR85_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NDR85_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NDR85_RS00280	COG4466	Protein conserved in bacteria
NDR85_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NDR85_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NDR85_RS00300	COG0251	oxidation-reduction process
NDR85_RS00305	COG2088	sporulation resulting in formation of a cellular spore
NDR85_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NDR85_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NDR85_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NDR85_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
NDR85_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NDR85_RS00340	COG2002	toxin-antitoxin pair type II binding
NDR85_RS00345	COG2244	polysaccharide biosynthetic process
NDR85_RS00350	COG3956	TIGRFAM MazG family protein
NDR85_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NDR85_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NDR85_RS00375	COG1098	S1 RNA binding domain
NDR85_RS00390	COG2208	phosphoserine phosphatase activity
NDR85_RS00395	COG2304	oxidoreductase activity
NDR85_RS00400	COG0515	serine threonine protein kinase
NDR85_RS00405	COG0037	tRNA processing
NDR85_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NDR85_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NDR85_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NDR85_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NDR85_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NDR85_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NDR85_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDR85_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
NDR85_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDR85_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NDR85_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NDR85_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NDR85_RS00470	COG1396	sequence-specific DNA binding
NDR85_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDR85_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NDR85_RS00560	COG4463	regulation of RNA biosynthetic process
NDR85_RS00565	COG3880	PFAM UvrB UvrC protein
NDR85_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NDR85_RS00575	COG0542	response to heat
NDR85_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NDR85_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NDR85_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
NDR85_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NDR85_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NDR85_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NDR85_RS00610	COG1045	serine acetyltransferase
NDR85_RS00615	COG0215	cysteine-tRNA ligase activity
NDR85_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDR85_RS00630	COG3688	RNA-binding protein containing a PIN domain
NDR85_RS00635	COG1595	DNA-templated transcription, initiation
NDR85_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NDR85_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
NDR85_RS00660	COG0081	regulation of translation
NDR85_RS00675	COG2813	Specifically methylates the guanine in position
NDR85_RS00680	COG0085	RNA polymerase activity
NDR85_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NDR85_RS00690	COG1358	cellular component organization or biogenesis
NDR85_RS00700	COG0049	tRNA binding
NDR85_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NDR85_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NDR85_RS00715	COG0596	Alpha beta hydrolase
NDR85_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NDR85_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NDR85_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NDR85_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NDR85_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NDR85_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NDR85_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NDR85_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NDR85_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NDR85_RS00820	COG0200	Binds to the 23S rRNA
NDR85_RS00825	COG0201	protein transport
NDR85_RS00830	COG0563	adenylate kinase activity
NDR85_RS00835	COG0024	Methionine aminopeptidase
NDR85_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NDR85_RS00860	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NDR85_RS00865	COG0202	RNA polymerase activity
NDR85_RS00870	COG0203	ribosomal protein L17
NDR85_RS00875	COG1122	ATPase activity
NDR85_RS00880	COG1122	ATPase activity
NDR85_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDR85_RS00890	COG0101	tRNA pseudouridine synthase activity
NDR85_RS00895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NDR85_RS00905	COG2226	methyltransferase
NDR85_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS00920	COG0489	protein tyrosine kinase activity
NDR85_RS00930	COG2194	sulfuric ester hydrolase activity
NDR85_RS00935	COG0726	polysaccharide deacetylase
NDR85_RS01015	COG0659	secondary active sulfate transmembrane transporter activity
NDR85_RS01020	COG0385	Bile acid
NDR85_RS01025	COG2819	hydrolase of the alpha beta superfamily
NDR85_RS01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS01040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NDR85_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NDR85_RS01045	COG2207	Transcriptional regulator
NDR85_RS01050	COG3876	Protein conserved in bacteria
NDR85_RS01055	COG1472	Belongs to the glycosyl hydrolase 3 family
NDR85_RS01060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDR85_RS01065	COG1263	PTS System
NDR85_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS01070	COG1737	Transcriptional regulator
NDR85_RS01075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NDR85_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS01085	COG1683	Conserved Protein
NDR85_RS01115	COG1595	DNA-templated transcription, initiation
NDR85_RS01120	COG5662	AntiSigma factor
NDR85_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NDR85_RS01130	COG4856	YbbR-like protein
NDR85_RS01135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDR85_RS01140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NDR85_RS01150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NDR85_RS01155	COG3002	Belongs to the UPF0753 family
NDR85_RS01160	COG0288	reversible hydration of carbon dioxide
NDR85_RS01170	COG5609	conserved protein (DUF2294)
NDR85_RS01175	COG0640	Transcriptional regulator
NDR85_RS01180	COG2814	Major facilitator Superfamily
NDR85_RS01195	COG2205	protein histidine kinase activity
NDR85_RS01205	COG0596	Alpha beta hydrolase
NDR85_RS01210	COG0745	RESPONSE REGULATOR receiver
NDR85_RS01215	COG0642	Histidine kinase
NDR85_RS01225	COG0515	serine threonine protein kinase
NDR85_RS01240	COG1113	amino acid transport
NDR85_RS01255	COG2602	Beta-lactamase
NDR85_RS01260	COG2124	cytochrome p450
NDR85_RS01270	COG0531	amino acid
NDR85_RS01275	COG0584	glycerophosphoryl diester phosphodiesterase
NDR85_RS01280	COG2271	Major facilitator Superfamily
NDR85_RS01290	COG1846	Transcriptional regulator
NDR85_RS01290	COG0456	acetyltransferase
NDR85_RS01295	COG2271	Major facilitator Superfamily
NDR85_RS01305	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS01315	COG0371	Dehydrogenase
NDR85_RS01320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NDR85_RS01325	COG3591	Belongs to the peptidase S1B family
NDR85_RS01335	COG0596	Alpha beta hydrolase
NDR85_RS01340	COG1183	phosphatidylcholine synthase activity
NDR85_RS01345	COG0586	Pfam SNARE associated Golgi protein
NDR85_RS01350	COG0688	phosphatidylethanolamine metabolic process
NDR85_RS01360	COG2312	Erythromycin esterase
NDR85_RS01365	COG2207	Transcriptional regulator
NDR85_RS01370	COG1054	Belongs to the UPF0176 family
NDR85_RS01380	COG1301	dicarboxylic acid transport
NDR85_RS01385	COG1263	PTS System
NDR85_RS01385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS01385	COG2190	(PTS) system
NDR85_RS01390	COG0363	glucosamine-6-phosphate deaminase activity
NDR85_RS01395	COG2188	Transcriptional regulator
NDR85_RS01405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDR85_RS01410	COG0833	amino acid
NDR85_RS01415	COG2040	homocysteine
NDR85_RS01420	COG1115	amino acid carrier protein
NDR85_RS01425	COG2066	Belongs to the glutaminase family
NDR85_RS01430	COG4191	Histidine kinase
NDR85_RS01435	COG0784	Response regulator, receiver
NDR85_RS01445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDR85_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS01455	COG2271	Major facilitator Superfamily
NDR85_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
NDR85_RS01465	COG2186	Transcriptional regulator
NDR85_RS01470	COG2721	sulfolactate sulfo-lyase activity
NDR85_RS01475	COG3173	Aminoglycoside phosphotransferase
NDR85_RS01485	COG0697	spore germination
NDR85_RS01490	COG0745	RESPONSE REGULATOR receiver
NDR85_RS01495	COG2205	protein histidine kinase activity
NDR85_RS01500	COG1131	(ABC) transporter
NDR85_RS01525	COG3773	Cell wall hydrolase
NDR85_RS01530	COG2304	oxidoreductase activity
NDR85_RS01540	COG3540	Alkaline phosphatase
NDR85_RS01545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDR85_RS01550	COG0805	protein transport
NDR85_RS01555	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NDR85_RS01560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDR85_RS01565	COG0477	Major facilitator Superfamily
NDR85_RS01570	COG1309	transcriptional regulator
NDR85_RS01575	COG0252	asparaginase activity
NDR85_RS01580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NDR85_RS01585	COG1714	RDD family
NDR85_RS01590	COG3012	SEC-C Motif Domain Protein
NDR85_RS01590	COG1405	negative regulation of cell septum assembly
NDR85_RS01595	COG3290	protein histidine kinase activity
NDR85_RS01600	COG3279	Response regulator of the LytR AlgR family
NDR85_RS01605	COG4555	ABC transporter
NDR85_RS01610	COG1668	transmembrane transport
NDR85_RS01615	COG0667	Aldo Keto reductase
NDR85_RS01630	COG1595	DNA-templated transcription, initiation
NDR85_RS01635	COG1595	DNA-templated transcription, initiation
NDR85_RS01640	COG1876	peptidase activity
NDR85_RS01645	COG0457	Tetratricopeptide repeat
NDR85_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS01655	COG0366	Alpha amylase catalytic
NDR85_RS01660	COG0803	Belongs to the bacterial solute-binding protein 9 family
NDR85_RS01665	COG1121	(ABC) transporter
NDR85_RS01670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NDR85_RS01675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDR85_RS01680	COG2310	stress, protein
NDR85_RS01685	COG2310	stress, protein
NDR85_RS01690	COG2310	stress, protein
NDR85_RS01695	COG0861	Integral membrane protein TerC family
NDR85_RS01710	COG1358	cellular component organization or biogenesis
NDR85_RS01725	COG3853	Toxic anion resistance protein (TelA)
NDR85_RS01730	COG0477	Major facilitator Superfamily
NDR85_RS01735	COG2814	Major facilitator Superfamily
NDR85_RS01740	COG0640	Transcriptional regulator
NDR85_RS01745	COG0517	IMP dehydrogenase activity
NDR85_RS01745	COG4175	Glycine betaine
NDR85_RS01750	COG4176	ABC-type proline glycine betaine transport system permease component
NDR85_RS01755	COG2113	Glycine betaine
NDR85_RS01760	COG1473	amidohydrolase
NDR85_RS01765	COG1288	antiporter activity
NDR85_RS01775	COG0366	Alpha amylase catalytic
NDR85_RS01780	COG0039	L-malate dehydrogenase activity
NDR85_RS01785	COG1620	l-lactate permease
NDR85_RS01790	COG2814	Major facilitator Superfamily
NDR85_RS01795	COG1846	Transcriptional regulator
NDR85_RS01800	COG1280	lysine exporter protein (LysE YggA)
NDR85_RS01805	COG3403	YqcI/YcgG family
NDR85_RS01810	COG1113	amino acid transport
NDR85_RS01815	COG3665	Urea carboxylase-associated protein
NDR85_RS01820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NDR85_RS01825	COG1660	Displays ATPase and GTPase activities
NDR85_RS01835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NDR85_RS01845	COG3458	cephalosporin-C deacetylase activity
NDR85_RS01850	COG3541	Predicted nucleotidyltransferase
NDR85_RS01855	COG0506	proline dehydrogenase activity
NDR85_RS01860	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS01865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDR85_RS01870	COG2508	Transcriptional regulator
NDR85_RS01875	COG3689	TIGRFAM TIGR03943 family protein
NDR85_RS01880	COG0701	Predicted permease
NDR85_RS01885	COG2267	carboxylic ester hydrolase activity
NDR85_RS01890	COG0492	ferredoxin-NADP+ reductase activity
NDR85_RS01895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDR85_RS01895	COG1587	Uroporphyrinogen-III synthase
NDR85_RS01900	COG2146	nitrite reductase [NAD(P)H] activity
NDR85_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDR85_RS01910	COG0243	molybdopterin cofactor binding
NDR85_RS01915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDR85_RS01920	COG2223	nitrite transmembrane transporter activity
NDR85_RS01925	COG1469	GTP cyclohydrolase I activity
NDR85_RS01945	COG0523	cobalamin synthesis protein
NDR85_RS01950	COG0765	amino acid transport
NDR85_RS01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDR85_RS01960	COG1063	alcohol dehydrogenase
NDR85_RS01975	COG3842	ATPase activity
NDR85_RS01980	COG2723	6-phospho-beta-galactosidase activity
NDR85_RS01990	COG3209	COG3209 Rhs family protein
NDR85_RS01995	COG0840	transmembrane signaling receptor activity
NDR85_RS01995	COG3290	protein histidine kinase activity
NDR85_RS02000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NDR85_RS02005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NDR85_RS02010	COG1733	regulation of RNA biosynthetic process
NDR85_RS02015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS02040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS02045	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NDR85_RS02050	COG2814	Major facilitator Superfamily
NDR85_RS02060	COG0697	spore germination
NDR85_RS02065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDR85_RS02075	COG2364	Membrane
NDR85_RS02080	COG1126	abc transporter atp-binding protein
NDR85_RS02085	COG0765	amino acid transport
NDR85_RS02090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDR85_RS02095	COG0583	DNA-binding transcription factor activity
NDR85_RS02105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NDR85_RS02120	COG0596	Alpha beta hydrolase
NDR85_RS02125	COG3104	oligopeptide transport
NDR85_RS02130	COG5434	Belongs to the glycosyl hydrolase 28 family
NDR85_RS02140	COG0697	spore germination
NDR85_RS02150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NDR85_RS02155	COG1136	(ABC) transporter
NDR85_RS02160	COG0577	efflux transmembrane transporter activity
NDR85_RS02165	COG0745	RESPONSE REGULATOR receiver
NDR85_RS02170	COG5002	protein histidine kinase activity
NDR85_RS02170	COG3850	Histidine kinase
NDR85_RS02175	COG0457	Tetratricopeptide repeat
NDR85_RS02195	COG0527	aspartate kinase activity
NDR85_RS02200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS02205	COG4605	iron ion homeostasis
NDR85_RS02210	COG4604	ABC transporter, ATP-binding protein
NDR85_RS02215	COG4607	ABC-type enterochelin transport system periplasmic component
NDR85_RS02220	COG2814	Major facilitator Superfamily
NDR85_RS02225	COG1309	transcriptional regulator
NDR85_RS02230	COG0778	Nitroreductase
NDR85_RS02235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NDR85_RS02240	COG0640	Transcriptional regulator
NDR85_RS02245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDR85_RS02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NDR85_RS02255	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS02260	COG4975	Glucose uptake
NDR85_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS02270	COG4549	nuclear export factor GLE1
NDR85_RS02275	COG1276	copper resistance
NDR85_RS02275	COG2372	response to copper ion
NDR85_RS02280	COG1349	DNA-binding transcription factor activity
NDR85_RS02290	COG2213	PTS system mannitol-specific
NDR85_RS02295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS02300	COG0246	Mannitol dehydrogenase
NDR85_RS02305	COG0473	3-isopropylmalate dehydrogenase activity
NDR85_RS02310	COG0412	Dienelactone hydrolase
NDR85_RS02315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NDR85_RS02325	COG0561	phosphatase activity
NDR85_RS02330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NDR85_RS02335	COG1914	H( )-stimulated, divalent metal cation uptake system
NDR85_RS02340	COG4336	lyase activity
NDR85_RS02345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NDR85_RS02350	COG1984	allophanate hydrolase subunit 2
NDR85_RS02355	COG1414	Transcriptional regulator
NDR85_RS02360	COG2755	lipolytic protein G-D-S-L family
NDR85_RS02370	COG2329	Antibiotic biosynthesis monooxygenase
NDR85_RS02375	COG0768	penicillin binding
NDR85_RS02380	COG4989	oxidoreductase activity
NDR85_RS02385	COG3711	transcriptional antiterminator
NDR85_RS02390	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS02395	COG2226	methyltransferase
NDR85_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS02405	COG1917	Cupin 2, conserved barrel domain protein
NDR85_RS02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS02415	COG3871	stress protein (general stress protein 26)
NDR85_RS02425	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDR85_RS02430	COG2814	Major facilitator Superfamily
NDR85_RS02445	COG1522	sequence-specific DNA binding
NDR85_RS02450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDR85_RS02450	COG0551	DNA topoisomerase type I activity
NDR85_RS02455	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NDR85_RS02460	COG3706	GGDEF domain
NDR85_RS02465	COG5298	Protein conserved in bacteria
NDR85_RS02470	COG1215	transferase activity, transferring glycosyl groups
NDR85_RS02480	COG0531	amino acid
NDR85_RS02485	COG0494	nUDIX hydrolase
NDR85_RS02490	COG0028	Belongs to the TPP enzyme family
NDR85_RS02500	COG1914	H( )-stimulated, divalent metal cation uptake system
NDR85_RS02505	COG2261	transglycosylase associated protein
NDR85_RS02510	COG4876	unkown
NDR85_RS02515	COG2217	Heavy metal translocating P-type atpase
NDR85_RS02520	COG3729	General stress protein
NDR85_RS02525	COG0662	Cupin 2, conserved barrel domain protein
NDR85_RS02530	COG2329	Antibiotic biosynthesis monooxygenase
NDR85_RS02540	COG3546	catalase activity
NDR85_RS02545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NDR85_RS02550	COG3290	protein histidine kinase activity
NDR85_RS02555	COG4565	transcriptional regulatory protein
NDR85_RS02560	COG1301	dicarboxylic acid transport
NDR85_RS02565	COG0628	permease
NDR85_RS02570	COG1301	dicarboxylic acid transport
NDR85_RS02575	COG1131	(ABC) transporter
NDR85_RS02580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NDR85_RS02590	COG1960	acyl-CoA dehydrogenase activity
NDR85_RS02605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDR85_RS02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS02615	COG1181	Belongs to the D-alanine--D-alanine ligase family
NDR85_RS02620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NDR85_RS02625	COG0513	Belongs to the DEAD box helicase family
NDR85_RS02630	COG3402	PFAM membrane-flanked domain
NDR85_RS02635	COG3428	Bacterial PH domain
NDR85_RS02640	COG0705	Rhomboid family
NDR85_RS02645	COG0736	holo-[acyl-carrier-protein] synthase activity
NDR85_RS02650	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NDR85_RS02655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDR85_RS02660	COG0864	Transcriptional regulator
NDR85_RS02665	COG2337	Toxic component of a toxin-antitoxin (TA) module
NDR85_RS02670	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS02675	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS02680	COG2172	sigma factor antagonist activity
NDR85_RS02685	COG2208	phosphoserine phosphatase activity
NDR85_RS02690	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS02695	COG2172	sigma factor antagonist activity
NDR85_RS02700	COG1191	sigma factor activity
NDR85_RS02705	COG2208	phosphoserine phosphatase activity
NDR85_RS02710	COG2183	response to ionizing radiation
NDR85_RS02720	COG3091	SprT-like family
NDR85_RS02760	COG0582	viral genome integration into host DNA
NDR85_RS02765	COG2856	Zn peptidase
NDR85_RS02770	COG1396	sequence-specific DNA binding
NDR85_RS02800	COG1674	ftsk spoiiie
NDR85_RS02805	COG2946	Replication initiation factor
NDR85_RS02835	COG0433	COG0433 Predicted ATPase
NDR85_RS02845	COG5644	endopeptidase inhibitor activity
NDR85_RS02850	COG0791	NLP P60 protein
NDR85_RS02850	COG0741	lytic transglycosylase activity
NDR85_RS02865	COG0457	Tetratricopeptide repeat
NDR85_RS02885	COG0251	oxidation-reduction process
NDR85_RS02890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NDR85_RS02900	COG0251	oxidation-reduction process
NDR85_RS02910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDR85_RS02920	COG0659	secondary active sulfate transmembrane transporter activity
NDR85_RS02925	COG0589	response to stress
NDR85_RS02940	COG2072	flavoprotein involved in K transport
NDR85_RS02970	COG5444	nuclease activity
NDR85_RS03000	COG2249	NAD(P)H dehydrogenase (quinone) activity
NDR85_RS03005	COG1309	transcriptional regulator
NDR85_RS03030	COG1846	Transcriptional regulator
NDR85_RS03055	COG1476	TRANSCRIPTIONal
NDR85_RS03065	COG3239	Fatty acid desaturase
NDR85_RS03070	COG1278	Cold shock
NDR85_RS03075	COG1278	Cold shock
NDR85_RS03080	COG1329	Transcriptional regulator
NDR85_RS03085	COG2315	Protein conserved in bacteria
NDR85_RS03090	COG0346	lactoylglutathione lyase activity
NDR85_RS03105	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NDR85_RS03115	COG2364	Membrane
NDR85_RS03120	COG1846	Transcriptional regulator
NDR85_RS03125	COG0456	acetyltransferase
NDR85_RS03130	COG2808	Putative FMN-binding domain
NDR85_RS03145	COG0693	protein deglycase activity
NDR85_RS03155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS03160	COG4257	antibiotic catabolic process
NDR85_RS03165	COG0456	acetyltransferase
NDR85_RS03170	COG3711	transcriptional antiterminator
NDR85_RS03170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS03175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS03175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDR85_RS03175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDR85_RS03180	COG1482	cell wall glycoprotein biosynthetic process
NDR85_RS03185	COG2030	dehydratase
NDR85_RS03190	COG0697	spore germination
NDR85_RS03195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDR85_RS03200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS03205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NDR85_RS03210	COG1522	sequence-specific DNA binding
NDR85_RS03220	COG2323	membrane
NDR85_RS03225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS03230	COG1309	transcriptional regulator
NDR85_RS03250	COG0673	inositol 2-dehydrogenase activity
NDR85_RS03255	COG1609	Transcriptional regulator
NDR85_RS03260	COG2814	Major facilitator Superfamily
NDR85_RS03265	COG1082	Xylose isomerase domain protein TIM barrel
NDR85_RS03270	COG0488	(ABC) transporter
NDR85_RS03275	COG1113	amino acid transport
NDR85_RS03280	COG2318	DinB family
NDR85_RS03285	COG1846	Transcriptional regulator
NDR85_RS03290	COG1033	growth of symbiont in host cell
NDR85_RS03290	COG2409	Drug exporters of the RND superfamily
NDR85_RS03300	COG0778	Nitroreductase
NDR85_RS03310	COG1396	sequence-specific DNA binding
NDR85_RS03315	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NDR85_RS03325	COG2814	Major facilitator Superfamily
NDR85_RS03330	COG0730	response to heat
NDR85_RS03335	COG1802	Transcriptional regulator
NDR85_RS03340	COG3858	chitin binding
NDR85_RS03340	COG1388	LysM domain
NDR85_RS03345	COG1819	glycosyl
NDR85_RS03355	COG1785	Belongs to the alkaline phosphatase family
NDR85_RS03370	COG1078	dGTPase activity
NDR85_RS03375	COG1388	LysM domain
NDR85_RS03380	COG2814	Major facilitator Superfamily
NDR85_RS03385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NDR85_RS03390	COG1447	Phosphotransferase system cellobiose-specific component IIA
NDR85_RS03395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NDR85_RS03400	COG2723	6-phospho-beta-galactosidase activity
NDR85_RS03405	COG2188	Transcriptional regulator
NDR85_RS03410	COG1940	carbohydrate kinase activity
NDR85_RS03415	COG1482	cell wall glycoprotein biosynthetic process
NDR85_RS03420	COG4124	Belongs to the glycosyl hydrolase 26 family
NDR85_RS03465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NDR85_RS03470	COG0802	atpase or kinase
NDR85_RS03475	COG1214	PFAM Peptidase M22, glycoprotease
NDR85_RS03480	COG0456	acetyltransferase
NDR85_RS03485	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NDR85_RS03490	COG0488	(ABC) transporter
NDR85_RS03495	COG0315	cyclic pyranopterin monophosphate synthase activity
NDR85_RS03500	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NDR85_RS03505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDR85_RS03510	COG0805	protein transport
NDR85_RS03520	COG1266	CAAX protease self-immunity
NDR85_RS03540	COG0457	Tetratricopeptide repeat
NDR85_RS03545	COG1063	alcohol dehydrogenase
NDR85_RS03550	COG2211	Major facilitator Superfamily
NDR85_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDR85_RS03565	COG2814	Major facilitator Superfamily
NDR85_RS03570	COG1063	alcohol dehydrogenase
NDR85_RS03575	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NDR85_RS03580	COG0823	Involved in the tonB-independent uptake of proteins
NDR85_RS03595	COG2267	carboxylic ester hydrolase activity
NDR85_RS03605	COG2132	Multicopper oxidase
NDR85_RS03610	COG1113	amino acid transport
NDR85_RS03615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NDR85_RS03620	COG0714	Associated with various cellular activities
NDR85_RS03625	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NDR85_RS03630	COG1305	Transglutaminase-like
NDR85_RS03635	COG0519	Catalyzes the synthesis of GMP from XMP
NDR85_RS03635	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NDR85_RS03650	COG2252	PERMEase
NDR85_RS03655	COG3064	Membrane
NDR85_RS03665	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NDR85_RS03675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NDR85_RS03680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NDR85_RS03685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NDR85_RS03690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NDR85_RS03695	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDR85_RS03700	COG0047	phosphoribosylformylglycinamidine synthase activity
NDR85_RS03705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NDR85_RS03710	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NDR85_RS03715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NDR85_RS03720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NDR85_RS03725	COG0138	bifunctional purine biosynthesis protein purh
NDR85_RS03730	COG0151	Belongs to the GarS family
NDR85_RS03735	COG1522	sequence-specific DNA binding
NDR85_RS03750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NDR85_RS03755	COG1470	cell adhesion involved in biofilm formation
NDR85_RS03760	COG4496	protein, YerC YecD
NDR85_RS03765	COG0069	glutamate synthase activity
NDR85_RS03770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NDR85_RS03775	COG0210	DNA helicase
NDR85_RS03780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NDR85_RS03785	COG4851	CamS sex pheromone cAM373 precursor
NDR85_RS03790	COG2211	Major facilitator Superfamily
NDR85_RS03795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NDR85_RS03800	COG1285	pathogenesis
NDR85_RS03805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDR85_RS03810	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDR85_RS03815	COG0154	amidase activity
NDR85_RS03820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NDR85_RS03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NDR85_RS03835	COG1597	lipid kinase activity
NDR85_RS03840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDR85_RS03845	COG0745	RESPONSE REGULATOR receiver
NDR85_RS03860	COG3852	Histidine kinase
NDR85_RS03865	COG1024	Enoyl-CoA hydratase
NDR85_RS03870	COG1024	Enoyl-CoA hydratase
NDR85_RS03875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS03880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NDR85_RS03890	COG3321	synthase
NDR85_RS03890	COG0604	alcohol dehydrogenase
NDR85_RS03895	COG1131	(ABC) transporter
NDR85_RS03910	COG4221	oxidoreductase activity
NDR85_RS03910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS03910	COG3321	synthase
NDR85_RS03915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS03915	COG0300	oxidoreductase activity
NDR85_RS03915	COG3321	synthase
NDR85_RS03915	COG4221	oxidoreductase activity
NDR85_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS03920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS03920	COG3321	synthase
NDR85_RS03920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS03920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS03925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS03925	COG3321	synthase
NDR85_RS03925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS03925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS03930	COG4221	oxidoreductase activity
NDR85_RS03930	COG3321	synthase
NDR85_RS03930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS03930	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS03935	COG3321	synthase
NDR85_RS03935	COG0300	oxidoreductase activity
NDR85_RS03935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS03935	COG4221	oxidoreductase activity
NDR85_RS03940	COG2070	2-Nitropropane dioxygenase
NDR85_RS03940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDR85_RS03945	COG3425	synthase
NDR85_RS03950	COG3391	amine dehydrogenase activity
NDR85_RS03955	COG0457	Tetratricopeptide repeat
NDR85_RS03965	COG0217	transcriptional regulatory protein
NDR85_RS03975	COG1309	transcriptional regulator
NDR85_RS03980	COG3631	Ketosteroid isomerase-related protein
NDR85_RS04010	COG3546	catalase activity
NDR85_RS04015	COG0454	-acetyltransferase
NDR85_RS04025	COG5578	integral membrane protein
NDR85_RS04030	COG2972	Histidine kinase
NDR85_RS04035	COG4753	response regulator
NDR85_RS04035	COG2207	Transcriptional regulator
NDR85_RS04040	COG1653	transport
NDR85_RS04045	COG1175	transmembrane transport
NDR85_RS04050	COG0395	ABC-type sugar transport system, permease component
NDR85_RS04055	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NDR85_RS04060	COG2207	Transcriptional regulator
NDR85_RS04065	COG2755	lipolytic protein G-D-S-L family
NDR85_RS04075	COG5578	integral membrane protein
NDR85_RS04080	COG3401	FG-GAP repeat protein
NDR85_RS04085	COG3401	FG-GAP repeat protein
NDR85_RS04090	COG0667	Aldo Keto reductase
NDR85_RS04095	COG2755	lipolytic protein G-D-S-L family
NDR85_RS04100	COG1874	Beta-galactosidase
NDR85_RS04110	COG1653	transport
NDR85_RS04115	COG4209	transmembrane transport
NDR85_RS04120	COG0395	ABC-type sugar transport system, permease component
NDR85_RS04125	COG1486	melibiose metabolic process
NDR85_RS04130	COG2323	membrane
NDR85_RS04135	COG2329	Antibiotic biosynthesis monooxygenase
NDR85_RS04140	COG0346	lactoylglutathione lyase activity
NDR85_RS04150	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS04155	COG5583	Uncharacterized small protein (DUF2292)
NDR85_RS04160	COG0670	Belongs to the BI1 family
NDR85_RS04165	COG1846	Transcriptional regulator
NDR85_RS04170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDR85_RS04180	COG2124	cytochrome p450
NDR85_RS04180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDR85_RS04185	COG1368	sulfuric ester hydrolase activity
NDR85_RS04190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NDR85_RS04195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS04200	COG1442	glycosyl transferase family 8
NDR85_RS04205	COG1216	Glycosyl transferase, family 2
NDR85_RS04210	COG1442	glycosyl transferase family 8
NDR85_RS04215	COG2223	nitrite transmembrane transporter activity
NDR85_RS04220	COG1011	Hydrolase
NDR85_RS04225	COG0531	amino acid
NDR85_RS04230	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS04235	COG0840	transmembrane signaling receptor activity
NDR85_RS04240	COG0488	(ABC) transporter
NDR85_RS04250	COG0789	Transcriptional regulator
NDR85_RS04255	COG2814	Major facilitator Superfamily
NDR85_RS04265	COG0488	(ABC) transporter
NDR85_RS04270	COG0513	Belongs to the DEAD box helicase family
NDR85_RS04275	COG0456	acetyltransferase
NDR85_RS04280	COG2130	NADP-dependent
NDR85_RS04285	COG1120	ATPase activity
NDR85_RS04290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS04295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS04300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NDR85_RS04315	COG3866	Pectate lyase
NDR85_RS04320	COG0471	metal ion transport
NDR85_RS04335	COG4565	transcriptional regulatory protein
NDR85_RS04340	COG3181	Tripartite tricarboxylate transporter family receptor
NDR85_RS04345	COG2851	Citrate transporter
NDR85_RS04350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS04355	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NDR85_RS04360	COG1254	Belongs to the acylphosphatase family
NDR85_RS04365	COG2258	MOSC domain
NDR85_RS04385	COG0024	Methionine aminopeptidase
NDR85_RS04390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS04390	COG1263	PTS System
NDR85_RS04395	COG1368	sulfuric ester hydrolase activity
NDR85_RS04405	COG1115	amino acid carrier protein
NDR85_RS04410	COG0531	amino acid
NDR85_RS04425	COG0697	spore germination
NDR85_RS04430	COG1263	PTS System
NDR85_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS04435	COG0366	Alpha amylase catalytic
NDR85_RS04440	COG2188	Transcriptional regulator
NDR85_RS04445	COG0778	Nitroreductase
NDR85_RS04450	COG0737	Belongs to the 5'-nucleotidase family
NDR85_RS04455	COG0693	protein deglycase activity
NDR85_RS04460	COG2814	Major facilitator Superfamily
NDR85_RS04465	COG4840	Belongs to the UPF0435 family
NDR85_RS04470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDR85_RS04475	COG4980	gas vesicle protein
NDR85_RS04480	COG1295	ribonuclease BN
NDR85_RS04485	COG0477	Major facilitator Superfamily
NDR85_RS04490	COG0387	Pfam Sodium calcium exchanger
NDR85_RS04500	COG0668	transmembrane transport
NDR85_RS04505	COG0535	radical SAM domain protein
NDR85_RS04515	COG0726	polysaccharide deacetylase
NDR85_RS04520	COG2084	Dehydrogenase
NDR85_RS04525	COG0598	Magnesium transport protein CorA
NDR85_RS04530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NDR85_RS04535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NDR85_RS04540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NDR85_RS04550	COG4637	Psort location Cytoplasmic, score
NDR85_RS04560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NDR85_RS04565	COG0022	dehydrogenase e1 component
NDR85_RS04570	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDR85_RS04575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDR85_RS04580	COG3284	Transcriptional regulator
NDR85_RS04590	COG1742	UPF0060 membrane protein
NDR85_RS04615	COG4842	Belongs to the WXG100 family
NDR85_RS04620	COG1486	melibiose metabolic process
NDR85_RS04625	COG1737	Transcriptional regulator
NDR85_RS04630	COG1263	PTS System
NDR85_RS04630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS04635	COG1132	(ABC) transporter
NDR85_RS04640	COG1132	(ABC) transporter
NDR85_RS04645	COG2259	Doxx family
NDR85_RS04650	COG2514	catechol 2,3-dioxygenase activity
NDR85_RS04655	COG4585	Histidine kinase
NDR85_RS04660	COG2197	response regulator
NDR85_RS04665	COG1131	(ABC) transporter
NDR85_RS04670	COG0842	Transport permease protein
NDR85_RS04670	COG1511	domain protein
NDR85_RS04675	COG0842	Transport permease protein
NDR85_RS04685	COG1695	Transcriptional regulator
NDR85_RS04690	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NDR85_RS04695	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NDR85_RS04700	COG1309	transcriptional regulator
NDR85_RS04705	COG2814	Major facilitator Superfamily
NDR85_RS04710	COG2318	DinB family
NDR85_RS04715	COG2814	Major facilitator Superfamily
NDR85_RS04720	COG1846	Transcriptional regulator
NDR85_RS04725	COG0392	lysyltransferase activity
NDR85_RS04725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NDR85_RS04730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NDR85_RS04735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS04745	COG0384	phenazine biosynthesis protein PhzF
NDR85_RS04750	COG0778	Nitroreductase
NDR85_RS04765	COG1090	epimerase
NDR85_RS04770	COG2137	regulation of response to DNA damage stimulus
NDR85_RS04780	COG2814	Major facilitator Superfamily
NDR85_RS04800	COG1476	TRANSCRIPTIONal
NDR85_RS04805	COG3103	Sh3 type 3 domain protein
NDR85_RS04810	COG5658	integral membrane protein
NDR85_RS04815	COG0596	Alpha beta hydrolase
NDR85_RS04820	COG0463	Glycosyl transferase, family 2
NDR85_RS04825	COG4485	Bacterial membrane protein, YfhO
NDR85_RS04830	COG1988	membrane-bound metal-dependent
NDR85_RS04835	COG1194	a g-specific adenine glycosylase
NDR85_RS04845	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS04860	COG3557	Belongs to the UPF0374 family
NDR85_RS04865	COG1132	(ABC) transporter
NDR85_RS04870	COG4129	membrane
NDR85_RS04875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NDR85_RS04880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NDR85_RS04885	COG0735	belongs to the Fur family
NDR85_RS04995	COG4326	sporulation control protein
NDR85_RS05005	COG1063	alcohol dehydrogenase
NDR85_RS05010	COG5577	PFAM Coat F domain
NDR85_RS05020	COG3340	Belongs to the peptidase S51 family
NDR85_RS05025	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NDR85_RS05035	COG0753	catalase activity
NDR85_RS05040	COG1116	anion transmembrane transporter activity
NDR85_RS05045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDR85_RS05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDR85_RS05055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDR85_RS05065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NDR85_RS05075	COG1476	TRANSCRIPTIONal
NDR85_RS05085	COG3382	B3 4 domain protein
NDR85_RS05090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NDR85_RS05100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NDR85_RS05105	COG0789	Transcriptional regulator
NDR85_RS05110	COG1664	Polymer-forming cytoskeletal
NDR85_RS05115	COG1664	Polymer-forming cytoskeletal
NDR85_RS05120	COG2766	serine protein kinase
NDR85_RS05125	COG2718	Belongs to the UPF0229 family
NDR85_RS05130	COG1846	Transcriptional regulator
NDR85_RS05140	COG2814	Major facilitator Superfamily
NDR85_RS05145	COG0655	NAD(P)H dehydrogenase (quinone) activity
NDR85_RS05160	COG1725	Transcriptional regulator
NDR85_RS05165	COG1131	(ABC) transporter
NDR85_RS05170	COG1131	(ABC) transporter
NDR85_RS05175	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NDR85_RS05180	COG1278	Cold shock
NDR85_RS05185	COG1464	Belongs to the NlpA lipoprotein family
NDR85_RS05190	COG3706	GGDEF domain
NDR85_RS05195	COG1823	symporter activity
NDR85_RS05200	COG5444	nuclease activity
NDR85_RS05240	COG5577	PFAM Coat F domain
NDR85_RS05245	COG0737	Belongs to the 5'-nucleotidase family
NDR85_RS05245	COG1525	nuclease
NDR85_RS05245	COG4085	toxin activity
NDR85_RS05250	COG3764	Sortase (surface protein transpeptidase)
NDR85_RS05255	COG0564	pseudouridine synthase activity
NDR85_RS05265	COG0517	IMP dehydrogenase activity
NDR85_RS05270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NDR85_RS05275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDR85_RS05275	COG3153	acetyltransferase
NDR85_RS05285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDR85_RS05290	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NDR85_RS05295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NDR85_RS05300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NDR85_RS05305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NDR85_RS05310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NDR85_RS05315	COG2203	Gaf domain
NDR85_RS05315	COG4585	Histidine kinase
NDR85_RS05320	COG2197	response regulator
NDR85_RS05325	COG0431	NADPH-dependent FMN reductase
NDR85_RS05340	COG0791	NLP P60 protein
NDR85_RS05340	COG1388	LysM domain
NDR85_RS05345	COG1959	2 iron, 2 sulfur cluster binding
NDR85_RS05355	COG2719	SpoVR family
NDR85_RS05365	COG1785	Belongs to the alkaline phosphatase family
NDR85_RS05370	COG0791	NLP P60 protein
NDR85_RS05370	COG1388	LysM domain
NDR85_RS05375	COG0583	DNA-binding transcription factor activity
NDR85_RS05380	COG0372	Belongs to the citrate synthase family
NDR85_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS05390	COG0531	amino acid
NDR85_RS05395	COG0733	neurotransmitter:sodium symporter activity
NDR85_RS05400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDR85_RS05405	COG0456	acetyltransferase
NDR85_RS05420	COG1595	DNA-templated transcription, initiation
NDR85_RS05425	COG0667	Aldo Keto reductase
NDR85_RS05430	COG0204	Acyl-transferase
NDR85_RS05435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDR85_RS05440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS05445	COG1253	flavin adenine dinucleotide binding
NDR85_RS05450	COG0789	Transcriptional regulator
NDR85_RS05455	COG0436	Aminotransferase
NDR85_RS05460	COG1253	flavin adenine dinucleotide binding
NDR85_RS05465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDR85_RS05470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NDR85_RS05475	COG0584	glycerophosphoryl diester phosphodiesterase
NDR85_RS05485	COG0668	transmembrane transport
NDR85_RS05490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NDR85_RS05495	COG0726	polysaccharide deacetylase
NDR85_RS05500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDR85_RS05505	COG1757	Na H antiporter
NDR85_RS05510	COG0589	response to stress
NDR85_RS05515	COG1132	(ABC) transporter
NDR85_RS05520	COG1132	(ABC) transporter
NDR85_RS05525	COG0702	epimerase
NDR85_RS05545	COG0189	ligase activity
NDR85_RS05550	COG0189	ligase activity
NDR85_RS05555	COG4399	Belongs to the UPF0754 family
NDR85_RS05560	COG3679	Belongs to the UPF0342 family
NDR85_RS05565	COG4335	DNA alkylation repair
NDR85_RS05570	COG0561	phosphatase activity
NDR85_RS05575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NDR85_RS05580	COG0475	glutathione-regulated potassium exporter activity
NDR85_RS05585	COG0490	domain, Protein
NDR85_RS05595	COG1024	Enoyl-CoA hydratase
NDR85_RS05605	COG4152	abc transporter atp-binding protein
NDR85_RS05610	COG1668	transmembrane transport
NDR85_RS05615	COG0420	3'-5' exonuclease activity
NDR85_RS05620	COG4717	serine-type aminopeptidase activity
NDR85_RS05625	COG3481	metal-dependent phosphohydrolase, HD sub domain
NDR85_RS05635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NDR85_RS05665	COG1846	Transcriptional regulator
NDR85_RS05670	COG4980	gas vesicle protein
NDR85_RS05685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NDR85_RS05690	COG0537	adenosine 5'-monophosphoramidase activity
NDR85_RS05695	COG1131	(ABC) transporter
NDR85_RS05700	COG4473	ABC transporter
NDR85_RS05710	COG1473	amidohydrolase
NDR85_RS05715	COG3069	C4-dicarboxylate transmembrane transporter activity
NDR85_RS05720	COG2329	Antibiotic biosynthesis monooxygenase
NDR85_RS05725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDR85_RS05730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NDR85_RS05735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NDR85_RS05740	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NDR85_RS05745	COG1309	transcriptional regulator
NDR85_RS05750	COG1511	domain protein
NDR85_RS05755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDR85_RS05760	COG4377	Putative membrane peptidase family (DUF2324)
NDR85_RS05770	COG1363	Peptidase, m42
NDR85_RS05775	COG4405	Protein conserved in bacteria
NDR85_RS05780	COG1301	dicarboxylic acid transport
NDR85_RS05790	COG1234	tRNA 3'-trailer cleavage
NDR85_RS05795	COG0095	Lipoate-protein ligase
NDR85_RS05800	COG0702	epimerase
NDR85_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS05815	COG0501	Belongs to the peptidase M48B family
NDR85_RS05820	COG1404	Belongs to the peptidase S8 family
NDR85_RS05825	COG0456	acetyltransferase
NDR85_RS05830	COG0604	alcohol dehydrogenase
NDR85_RS05835	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NDR85_RS05840	COG0406	alpha-ribazole phosphatase activity
NDR85_RS05845	COG0183	Belongs to the thiolase family
NDR85_RS05850	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS05855	COG1268	BioY protein
NDR85_RS05860	COG0840	transmembrane signaling receptor activity
NDR85_RS05865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDR85_RS05865	COG0723	plastoquinol--plastocyanin reductase activity
NDR85_RS05870	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS05880	COG4903	ComK protein
NDR85_RS05885	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS05895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDR85_RS05910	COG0398	Pfam SNARE associated Golgi protein
NDR85_RS05915	COG0681	Belongs to the peptidase S26 family
NDR85_RS05920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NDR85_RS05925	COG1846	Transcriptional regulator
NDR85_RS05935	COG0738	Major facilitator superfamily
NDR85_RS05940	COG0673	inositol 2-dehydrogenase activity
NDR85_RS05945	COG0561	phosphatase activity
NDR85_RS05950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NDR85_RS05955	COG1609	Transcriptional regulator
NDR85_RS05960	COG3180	Ammonia monooxygenase
NDR85_RS05965	COG0477	Major facilitator Superfamily
NDR85_RS05965	COG2814	Major facilitator Superfamily
NDR85_RS05970	COG4533	DNA binding
NDR85_RS05980	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NDR85_RS05985	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NDR85_RS05990	COG1074	ATP-dependent DNA helicase activity
NDR85_RS05995	COG0420	3'-5' exonuclease activity
NDR85_RS06000	COG0419	ATPase involved in DNA repair
NDR85_RS06005	COG1403	HNH endonuclease
NDR85_RS06045	COG5337	Spore coat protein CotH
NDR85_RS06050	COG0179	Fumarylacetoacetate (FAA) hydrolase
NDR85_RS06060	COG1404	Belongs to the peptidase S8 family
NDR85_RS06070	COG0367	asparagine synthase
NDR85_RS06075	COG2318	DinB family
NDR85_RS06085	COG0534	Mate efflux family protein
NDR85_RS06090	COG1917	Cupin 2, conserved barrel domain protein
NDR85_RS06090	COG2207	Transcriptional regulator
NDR85_RS06095	COG1609	Transcriptional regulator
NDR85_RS06100	COG0673	inositol 2-dehydrogenase activity
NDR85_RS06105	COG2318	DinB family
NDR85_RS06110	COG1279	arginine transmembrane transporter activity
NDR85_RS06115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NDR85_RS06120	COG1357	PFAM Pentapeptide repeats (8 copies)
NDR85_RS06125	COG2267	carboxylic ester hydrolase activity
NDR85_RS06130	COG0529	Catalyzes the synthesis of activated sulfate
NDR85_RS06135	COG2046	Belongs to the sulfate adenylyltransferase family
NDR85_RS06140	COG0175	sulfate reduction
NDR85_RS06145	COG2045	Belongs to the ComB family
NDR85_RS06150	COG1809	phosphosulfolactate synthase activity
NDR85_RS06155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS06160	COG4948	Mandelate Racemase Muconate Lactonizing
NDR85_RS06165	COG2814	Major facilitator Superfamily
NDR85_RS06170	COG0454	-acetyltransferase
NDR85_RS06175	COG2153	protein acetylation
NDR85_RS06180	COG0646	methionine synthase
NDR85_RS06180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NDR85_RS06185	COG1666	GTP binding
NDR85_RS06190	COG2996	Protein conserved in bacteria
NDR85_RS06210	COG1695	Transcriptional regulator
NDR85_RS06225	COG3227	Zinc metalloprotease (Elastase)
NDR85_RS06230	COG1307	EDD domain protein, DegV family
NDR85_RS06235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS06255	COG0561	phosphatase activity
NDR85_RS06260	COG1073	alpha beta
NDR85_RS06265	COG2151	metal-sulfur cluster biosynthetic enzyme
NDR85_RS06275	COG0277	FAD linked oxidase domain protein
NDR85_RS06280	COG2271	Major facilitator Superfamily
NDR85_RS06285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NDR85_RS06290	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NDR85_RS06300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDR85_RS06305	COG0505	Belongs to the CarA family
NDR85_RS06310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NDR85_RS06315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NDR85_RS06330	COG2267	carboxylic ester hydrolase activity
NDR85_RS06340	COG1744	ABC transporter substrate-binding protein PnrA-like
NDR85_RS06355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDR85_RS06360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NDR85_RS06365	COG5504	Zn-dependent protease
NDR85_RS06370	COG0444	Belongs to the ABC transporter superfamily
NDR85_RS06375	COG4608	Belongs to the ABC transporter superfamily
NDR85_RS06385	COG0601	transmembrane transport
NDR85_RS06390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDR85_RS06410	COG0180	Tryptophanyl-tRNA synthetase
NDR85_RS06415	COG4166	transmembrane transport
NDR85_RS06420	COG0601	transmembrane transport
NDR85_RS06425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDR85_RS06430	COG0444	Belongs to the ABC transporter superfamily
NDR85_RS06435	COG4608	Belongs to the ABC transporter superfamily
NDR85_RS06440	COG2814	Major facilitator Superfamily
NDR85_RS06445	COG0456	acetyltransferase
NDR85_RS06450	COG1393	Belongs to the ArsC family
NDR85_RS06455	COG0861	Integral membrane protein TerC family
NDR85_RS06465	COG4862	establishment of competence for transformation
NDR85_RS06470	COG4469	Competence protein
NDR85_RS06475	COG1164	Oligoendopeptidase f
NDR85_RS06485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NDR85_RS06490	COG2346	COG2346, Truncated hemoglobins
NDR85_RS06495	COG0741	lytic transglycosylase activity
NDR85_RS06500	COG4116	CYTH
NDR85_RS06510	COG2357	RelA SpoT domain protein
NDR85_RS06515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDR85_RS06520	COG0564	pseudouridine synthase activity
NDR85_RS06525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NDR85_RS06530	COG0475	glutathione-regulated potassium exporter activity
NDR85_RS06530	COG0569	domain protein
NDR85_RS06535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NDR85_RS06540	COG0352	thiamine-phosphate diphosphorylase activity
NDR85_RS06545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDR85_RS06550	COG2104	thiamine diphosphate biosynthetic process
NDR85_RS06555	COG2022	thiamine diphosphate biosynthetic process
NDR85_RS06560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDR85_RS06565	COG0351	phosphomethylpyrimidine kinase
NDR85_RS06570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NDR85_RS06625	COG0210	DNA helicase
NDR85_RS06635	COG2153	protein acetylation
NDR85_RS06640	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NDR85_RS06645	COG2382	esterase
NDR85_RS06650	COG0626	cystathionine gamma-synthase activity
NDR85_RS06655	COG0626	cystathionine gamma-synthase activity
NDR85_RS06660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS06685	COG5444	nuclease activity
NDR85_RS06690	COG0457	Tetratricopeptide repeat
NDR85_RS06750	COG0457	Tetratricopeptide repeat
NDR85_RS06805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS06815	COG0789	Transcriptional regulator
NDR85_RS06830	COG1846	Transcriptional regulator
NDR85_RS06845	COG1335	isochorismatase
NDR85_RS06885	COG0109	protoheme IX farnesyltransferase activity
NDR85_RS06895	COG0726	polysaccharide deacetylase
NDR85_RS06910	COG5504	Zn-dependent protease
NDR85_RS06915	COG2205	protein histidine kinase activity
NDR85_RS06925	COG3383	formate dehydrogenase (NAD+) activity
NDR85_RS06930	COG2427	Protein of unknown function (DUF1641)
NDR85_RS06940	COG1051	belongs to the nudix hydrolase family
NDR85_RS06950	COG2124	cytochrome p450
NDR85_RS06955	COG1819	glycosyl
NDR85_RS06970	COG1587	Uroporphyrinogen-III synthase
NDR85_RS06975	COG0390	transport system, permease component
NDR85_RS06980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NDR85_RS06985	COG0697	spore germination
NDR85_RS06990	COG4297	protein containing double-stranded beta helix domain
NDR85_RS07000	COG1252	NADH dehydrogenase
NDR85_RS07005	COG1904	glucuronate isomerase
NDR85_RS07010	COG2211	Major facilitator Superfamily
NDR85_RS07015	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NDR85_RS07020	COG1063	alcohol dehydrogenase
NDR85_RS07025	COG1312	Catalyzes the dehydration of D-mannonate
NDR85_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS07035	COG2271	Major facilitator Superfamily
NDR85_RS07040	COG1609	Transcriptional regulator
NDR85_RS07045	COG0246	Mannitol dehydrogenase
NDR85_RS07050	COG2721	sulfolactate sulfo-lyase activity
NDR85_RS07055	COG0730	response to heat
NDR85_RS07060	COG2318	DinB family
NDR85_RS07065	COG0457	Tetratricopeptide repeat
NDR85_RS07075	COG2350	Protein conserved in bacteria
NDR85_RS07080	COG5632	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS07080	COG1388	LysM domain
NDR85_RS07080	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS07090	COG4195	phage-related replication protein
NDR85_RS07095	COG3546	catalase activity
NDR85_RS07100	COG2856	Zn peptidase
NDR85_RS07105	COG1396	sequence-specific DNA binding
NDR85_RS07115	COG1522	sequence-specific DNA binding
NDR85_RS07120	COG1484	DNA-dependent DNA replication
NDR85_RS07140	COG1595	DNA-templated transcription, initiation
NDR85_RS07145	COG3728	DNA packaging
NDR85_RS07145	COG5484	DNA packaging
NDR85_RS07150	COG1783	phage Terminase large subunit
NDR85_RS07155	COG5518	Phage portal protein
NDR85_RS07160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NDR85_RS07215	COG3953	SLT domain
NDR85_RS07215	COG5412	phage tail tape measure protein
NDR85_RS07220	COG1652	LysM domain
NDR85_RS07225	COG4193	domain, Protein
NDR85_RS07235	COG3628	GPW Gp25 family protein
NDR85_RS07240	COG3299	homolog of phage Mu protein gp47
NDR85_RS07245	COG3778	Protein conserved in bacteria
NDR85_RS07290	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS07290	COG5632	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS07310	COG0306	phosphate transporter
NDR85_RS07315	COG1392	Phosphate transport regulator
NDR85_RS07320	COG0531	amino acid
NDR85_RS07325	COG0346	lactoylglutathione lyase activity
NDR85_RS07335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NDR85_RS07340	COG0463	Glycosyl transferase, family 2
NDR85_RS07350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDR85_RS07355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDR85_RS07360	COG2362	D-Aminopeptidase
NDR85_RS07365	COG0601	transmembrane transport
NDR85_RS07370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NDR85_RS07375	COG0444	Belongs to the ABC transporter superfamily
NDR85_RS07380	COG4166	transmembrane transport
NDR85_RS07385	COG1619	proteins homologs of microcin C7 resistance protein MccF
NDR85_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
NDR85_RS07395	COG0791	NLP P60 protein
NDR85_RS07400	COG4608	Belongs to the ABC transporter superfamily
NDR85_RS07405	COG2706	6-phosphogluconolactonase activity
NDR85_RS07410	COG1834	amidinotransferase
NDR85_RS07415	COG1607	acyl-coa hydrolase
NDR85_RS07420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NDR85_RS07420	COG1017	nitric oxide dioxygenase activity
NDR85_RS07430	COG2323	membrane
NDR85_RS07435	COG2318	DinB family
NDR85_RS07440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS07445	COG2076	Multidrug Resistance protein
NDR85_RS07450	COG2076	Multidrug Resistance protein
NDR85_RS07455	COG0788	formyltetrahydrofolate deformylase activity
NDR85_RS07460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDR85_RS07465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NDR85_RS07470	COG1764	response to oxidative stress
NDR85_RS07475	COG1846	Transcriptional regulator
NDR85_RS07480	COG1764	response to oxidative stress
NDR85_RS07485	COG0463	Glycosyl transferase, family 2
NDR85_RS07485	COG0457	Tetratricopeptide repeat
NDR85_RS07495	COG0590	tRNA wobble adenosine to inosine editing
NDR85_RS07500	COG0406	alpha-ribazole phosphatase activity
NDR85_RS07505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NDR85_RS07510	COG1404	Belongs to the peptidase S8 family
NDR85_RS07515	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS07520	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NDR85_RS07525	COG1122	ATPase activity
NDR85_RS07530	COG4721	ABC-type cobalt transport system, permease component
NDR85_RS07540	COG0745	RESPONSE REGULATOR receiver
NDR85_RS07545	COG3850	Histidine kinase
NDR85_RS07545	COG5002	protein histidine kinase activity
NDR85_RS07555	COG3212	peptidase
NDR85_RS07570	COG2239	Acts as a magnesium transporter
NDR85_RS07575	COG0789	Transcriptional regulator
NDR85_RS07590	COG1846	Transcriptional regulator
NDR85_RS07595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NDR85_RS07600	COG0726	polysaccharide deacetylase
NDR85_RS07605	COG1408	metallophosphoesterase
NDR85_RS07615	COG0463	Glycosyl transferase, family 2
NDR85_RS07620	COG1793	dna ligase
NDR85_RS07620	COG3285	dna ligase
NDR85_RS07625	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NDR85_RS07630	COG3300	MHYT domain
NDR85_RS07630	COG5001	Diguanylate cyclase
NDR85_RS07635	COG0586	Pfam SNARE associated Golgi protein
NDR85_RS07645	COG1191	sigma factor activity
NDR85_RS07665	COG0501	Belongs to the peptidase M48B family
NDR85_RS07670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NDR85_RS07685	COG3594	Acyltransferase
NDR85_RS07690	COG5002	protein histidine kinase activity
NDR85_RS07695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NDR85_RS07705	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NDR85_RS07710	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NDR85_RS07715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NDR85_RS07720	COG0436	Aminotransferase
NDR85_RS07725	COG1850	ribulose-bisphosphate carboxylase activity
NDR85_RS07730	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NDR85_RS07735	COG0235	Class ii aldolase
NDR85_RS07740	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NDR85_RS07745	COG3339	Conserved Protein
NDR85_RS07760	COG3852	Histidine kinase
NDR85_RS07765	COG1846	Transcriptional regulator
NDR85_RS07770	COG1360	Flagellar Motor Protein
NDR85_RS07775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NDR85_RS07780	COG0542	response to heat
NDR85_RS07785	COG3949	Membrane
NDR85_RS07790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NDR85_RS07795	COG0720	synthase
NDR85_RS07800	COG0602	queuosine metabolic process
NDR85_RS07805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NDR85_RS07810	COG1388	LysM domain
NDR85_RS07810	COG4641	Protein conserved in bacteria
NDR85_RS07815	COG1388	LysM domain
NDR85_RS07820	COG3858	chitin binding
NDR85_RS07830	COG4873	Protein conserved in bacteria
NDR85_RS07840	COG3773	Cell wall hydrolase
NDR85_RS07845	COG2244	polysaccharide biosynthetic process
NDR85_RS07850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS07855	COG2217	Heavy metal translocating P-type atpase
NDR85_RS07865	COG0006	proline dipeptidase activity
NDR85_RS07875	COG1609	Transcriptional regulator
NDR85_RS07880	COG3711	transcriptional antiterminator
NDR85_RS07885	COG1263	PTS System
NDR85_RS07885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS07885	COG2190	(PTS) system
NDR85_RS07890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS07895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NDR85_RS07905	COG1533	DNA photolyase activity
NDR85_RS07910	COG0456	acetyltransferase
NDR85_RS07915	COG0840	transmembrane signaling receptor activity
NDR85_RS07920	COG2084	Dehydrogenase
NDR85_RS07950	COG2340	Cysteine-rich secretory protein family
NDR85_RS07955	COG0768	penicillin binding
NDR85_RS07960	COG4191	Histidine kinase
NDR85_RS07965	COG0436	Aminotransferase
NDR85_RS07975	COG0835	chemotaxis
NDR85_RS07975	COG0784	Response regulator, receiver
NDR85_RS07985	COG2814	Major facilitator Superfamily
NDR85_RS07990	COG1376	ErfK ybiS ycfS ynhG family protein
NDR85_RS07995	COG1408	metallophosphoesterase
NDR85_RS08000	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS08005	COG2200	EAL domain
NDR85_RS08010	COG3546	catalase activity
NDR85_RS08015	COG4703	Protein of unknown function (DUF1797)
NDR85_RS08020	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NDR85_RS08030	COG0517	IMP dehydrogenase activity
NDR85_RS08040	COG0716	FMN binding
NDR85_RS08050	COG0716	FMN binding
NDR85_RS08055	COG2171	N-acyltransferase activity
NDR85_RS08060	COG1473	amidohydrolase
NDR85_RS08070	COG0668	transmembrane transport
NDR85_RS08075	COG0450	alkyl hydroperoxide reductase
NDR85_RS08080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS08095	COG0746	molybdenum cofactor guanylyltransferase activity
NDR85_RS08100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NDR85_RS08105	COG0303	'Molybdopterin
NDR85_RS08110	COG1763	Mo-molybdopterin cofactor biosynthetic process
NDR85_RS08115	COG0314	molybdopterin synthase activity
NDR85_RS08120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NDR85_RS08125	COG1132	(ABC) transporter
NDR85_RS08130	COG1132	(ABC) transporter
NDR85_RS08140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDR85_RS08145	COG1136	(ABC) transporter
NDR85_RS08150	COG0577	efflux transmembrane transporter activity
NDR85_RS08155	COG1349	DNA-binding transcription factor activity
NDR85_RS08160	COG1105	Belongs to the carbohydrate kinase PfkB family
NDR85_RS08165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDR85_RS08165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NDR85_RS08165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS08170	COG0681	Belongs to the peptidase S26 family
NDR85_RS08185	COG0488	(ABC) transporter
NDR85_RS08190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDR85_RS08195	COG2309	aminopeptidase activity
NDR85_RS08205	COG1077	Cell shape determining protein MreB Mrl
NDR85_RS08210	COG2002	toxin-antitoxin pair type II binding
NDR85_RS08215	COG3852	Histidine kinase
NDR85_RS08220	COG2105	PFAM AIG2 family protein
NDR85_RS08220	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NDR85_RS08225	COG0569	domain protein
NDR85_RS08230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NDR85_RS08235	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NDR85_RS08240	COG5503	Protein of unknown function (DUF1447)
NDR85_RS08245	COG0561	phosphatase activity
NDR85_RS08250	COG0242	peptide deformylase activity
NDR85_RS08260	COG0497	DNA recombination
NDR85_RS08265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NDR85_RS08270	COG0022	dehydrogenase e1 component
NDR85_RS08275	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDR85_RS08280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDR85_RS08285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS08295	COG1982	Orn Lys Arg decarboxylase major
NDR85_RS08300	COG4476	Belongs to the UPF0223 family
NDR85_RS08305	COG4493	Belongs to the UPF0637 family
NDR85_RS08315	COG0483	inositol monophosphate 1-phosphatase activity
NDR85_RS08325	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NDR85_RS08355	COG1217	gtp-binding protein TYPA
NDR85_RS08365	COG4896	Protein conserved in bacteria
NDR85_RS08375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NDR85_RS08380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NDR85_RS08385	COG2066	Belongs to the glutaminase family
NDR85_RS08390	COG4838	Belongs to the UPF0358 family
NDR85_RS08395	COG0772	Belongs to the SEDS family
NDR85_RS08400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NDR85_RS08405	COG1612	heme a metabolic process
NDR85_RS08410	COG0109	protoheme IX farnesyltransferase activity
NDR85_RS08415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NDR85_RS08415	COG2010	Cytochrome c
NDR85_RS08420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDR85_RS08425	COG1845	cytochrome c oxidase, subunit III
NDR85_RS08430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NDR85_RS08435	COG3336	cytochrome c oxidase
NDR85_RS08445	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NDR85_RS08450	COG2340	Cysteine-rich secretory protein family
NDR85_RS08465	COG3679	Belongs to the UPF0342 family
NDR85_RS08470	COG4471	UPF0298 protein
NDR85_RS08475	COG0742	ribosomal rna small subunit methyltransferase
NDR85_RS08480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NDR85_RS08485	COG3314	Sporulation integral membrane protein YlbJ
NDR85_RS08490	COG1752	Esterase of the alpha-beta hydrolase superfamily
NDR85_RS08495	COG3480	Lon protease (S16) C-terminal proteolytic domain
NDR85_RS08500	COG1323	Belongs to the UPF0348 family
NDR85_RS08510	COG1399	metal-binding, possibly nucleic acid-binding protein
NDR85_RS08525	COG0454	-acetyltransferase
NDR85_RS08530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NDR85_RS08535	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NDR85_RS08540	COG2001	Belongs to the MraZ family
NDR85_RS08545	COG0275	rRNA processing
NDR85_RS08550	COG4839	cell division protein FtsL
NDR85_RS08555	COG0768	penicillin binding
NDR85_RS08560	COG0768	penicillin binding
NDR85_RS08565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NDR85_RS08570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NDR85_RS08575	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NDR85_RS08580	COG0772	Belongs to the SEDS family
NDR85_RS08585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NDR85_RS08590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NDR85_RS08595	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NDR85_RS08600	COG3879	Bacterial protein of unknown function (DUF881)
NDR85_RS08605	COG3879	Bacterial protein of unknown function (DUF881)
NDR85_RS08610	COG3856	small basic protein
NDR85_RS08615	COG0849	cell division
NDR85_RS08620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NDR85_RS08625	COG1404	Belongs to the peptidase S8 family
NDR85_RS08625	COG4412	M6 family metalloprotease domain protein
NDR85_RS08635	COG1191	sigma factor activity
NDR85_RS08640	COG1191	sigma factor activity
NDR85_RS08645	COG1119	ATPase activity
NDR85_RS08650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDR85_RS08655	COG1873	PFAM PRC-barrel domain
NDR85_RS08660	COG1496	oxidoreductase activity
NDR85_RS08665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NDR85_RS08670	COG1799	cell septum assembly
NDR85_RS08675	COG0762	integral membrane protein
NDR85_RS08680	COG2302	S4 RNA-binding domain
NDR85_RS08685	COG3599	regulation of cell shape
NDR85_RS08690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NDR85_RS08695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NDR85_RS08700	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NDR85_RS08705	COG0564	pseudouridine synthase activity
NDR85_RS08710	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NDR85_RS08715	COG2233	PERMEase
NDR85_RS08720	COG0540	Belongs to the ATCase OTCase family
NDR85_RS08725	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NDR85_RS08730	COG0505	Belongs to the CarA family
NDR85_RS08735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NDR85_RS08740	COG0543	2 iron, 2 sulfur cluster binding
NDR85_RS08745	COG0167	dihydroorotate dehydrogenase activity
NDR85_RS08750	COG0284	orotidine-5'-phosphate decarboxylase activity
NDR85_RS08755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NDR85_RS08760	COG0175	sulfate reduction
NDR85_RS08765	COG0306	phosphate transporter
NDR85_RS08770	COG2046	Belongs to the sulfate adenylyltransferase family
NDR85_RS08775	COG0529	Catalyzes the synthesis of activated sulfate
NDR85_RS08780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NDR85_RS08785	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NDR85_RS08790	COG1648	precorrin-2 dehydrogenase activity
NDR85_RS08795	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NDR85_RS08800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NDR85_RS08805	COG1561	YicC-like family, N-terminal region
NDR85_RS08815	COG0194	GDP metabolic process
NDR85_RS08820	COG1758	RNA polymerase activity
NDR85_RS08825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDR85_RS08830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NDR85_RS08835	COG0242	peptide deformylase activity
NDR85_RS08840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NDR85_RS08845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NDR85_RS08845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDR85_RS08850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NDR85_RS08855	COG0631	protein serine/threonine phosphatase activity
NDR85_RS08860	COG0515	serine threonine protein kinase
NDR85_RS08860	COG2815	serine threonine protein kinase
NDR85_RS08865	COG1162	GTPase activity
NDR85_RS08870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NDR85_RS08875	COG1564	THIamine pyrophosphokinase
NDR85_RS08885	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NDR85_RS08890	COG1302	Protein conserved in bacteria
NDR85_RS08895	COG1461	Dihydroxyacetone kinase
NDR85_RS08900	COG1760	l-serine dehydratase
NDR85_RS08905	COG1760	l-serine dehydratase
NDR85_RS08910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NDR85_RS08915	COG1349	DNA-binding transcription factor activity
NDR85_RS08915	COG2050	protein possibly involved in aromatic compounds catabolism
NDR85_RS08920	COG0416	fatty acid biosynthetic process
NDR85_RS08925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDR85_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS08940	COG0571	ribonuclease III activity
NDR85_RS08945	COG1196	nuclear chromosome segregation
NDR85_RS08950	COG1196	nuclear chromosome segregation
NDR85_RS08955	COG0552	protein localization to endoplasmic reticulum
NDR85_RS08965	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NDR85_RS08970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NDR85_RS08975	COG0228	four-way junction DNA binding
NDR85_RS08980	COG1837	Belongs to the UPF0109 family
NDR85_RS08990	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NDR85_RS08995	COG0336	Belongs to the RNA methyltransferase TrmD family
NDR85_RS09000	COG0335	large ribosomal subunit rRNA binding
NDR85_RS09005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NDR85_RS09010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDR85_RS09020	COG2257	FlhB HrpN YscU SpaS Family
NDR85_RS09025	COG0045	succinate-CoA ligase (ADP-forming) activity
NDR85_RS09030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NDR85_RS09035	COG0758	DNA mediated transformation
NDR85_RS09040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NDR85_RS09045	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NDR85_RS09050	COG4974	Belongs to the 'phage' integrase family
NDR85_RS09055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NDR85_RS09060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NDR85_RS09065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NDR85_RS09070	COG1815	bacterial-type flagellum-dependent cell motility
NDR85_RS09075	COG1558	bacterial-type flagellum-dependent cell motility
NDR85_RS09080	COG1677	Flagellar hook-basal body complex protein FliE
NDR85_RS09085	COG1766	The M ring may be actively involved in energy transduction
NDR85_RS09090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NDR85_RS09095	COG1317	bacterial-type flagellum organization
NDR85_RS09100	COG1157	protein secretion by the type III secretion system
NDR85_RS09105	COG2882	bacterial-type flagellum organization
NDR85_RS09110	COG3334	PFAM MgtE intracellular
NDR85_RS09115	COG3144	bacterial-type flagellum assembly
NDR85_RS09120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NDR85_RS09125	COG4786	Flagellar basal body rod
NDR85_RS09130	COG1582	Flagellar protein (FlbD)
NDR85_RS09135	COG1580	Controls the rotational direction of flagella during chemotaxis
NDR85_RS09140	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NDR85_RS09145	COG1776	CheC inhibitor of MCP methylation
NDR85_RS09145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NDR85_RS09150	COG2201	protein-glutamate methylesterase activity
NDR85_RS09155	COG3190	flagellar
NDR85_RS09160	COG1338	Plays a role in the flagellum-specific transport system
NDR85_RS09165	COG1987	bacterial-type flagellum assembly
NDR85_RS09170	COG1684	flagellar biosynthetic protein fliR
NDR85_RS09175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDR85_RS09180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NDR85_RS09185	COG1419	protein localization to endoplasmic reticulum
NDR85_RS09190	COG0455	bacterial-type flagellum organization
NDR85_RS09195	COG2201	protein-glutamate methylesterase activity
NDR85_RS09200	COG0643	Histidine kinase
NDR85_RS09200	COG2198	Histidine kinase
NDR85_RS09205	COG0835	chemotaxis
NDR85_RS09210	COG1776	CheC inhibitor of MCP methylation
NDR85_RS09215	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NDR85_RS09220	COG1191	sigma factor activity
NDR85_RS09230	COG0052	Belongs to the universal ribosomal protein uS2 family
NDR85_RS09235	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NDR85_RS09240	COG0528	UMP kinase activity
NDR85_RS09245	COG0233	cytoplasmic translational termination
NDR85_RS09250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NDR85_RS09255	COG4589	Belongs to the CDS family
NDR85_RS09260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NDR85_RS09265	COG0750	zinc metalloprotease
NDR85_RS09270	COG0442	prolyl-tRNA aminoacylation
NDR85_RS09275	COG2176	DNA-directed DNA polymerase activity
NDR85_RS09280	COG0779	Required for maturation of 30S ribosomal subunits
NDR85_RS09285	COG0195	Participates in both transcription termination and antitermination
NDR85_RS09290	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NDR85_RS09295	COG1358	cellular component organization or biogenesis
NDR85_RS09300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NDR85_RS09305	COG1550	Protein conserved in bacteria
NDR85_RS09310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NDR85_RS09315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NDR85_RS09320	COG0196	riboflavin kinase activity
NDR85_RS09330	COG1185	polyribonucleotide nucleotidyltransferase activity
NDR85_RS09335	COG0726	polysaccharide deacetylase
NDR85_RS09340	COG0612	Peptidase, M16
NDR85_RS09345	COG1873	PFAM PRC-barrel domain
NDR85_RS09350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDR85_RS09355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NDR85_RS09360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NDR85_RS09365	COG0527	aspartate kinase activity
NDR85_RS09370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NDR85_RS09375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NDR85_RS09380	COG0740	serine-type endopeptidase activity
NDR85_RS09390	COG1674	ftsk spoiiie
NDR85_RS09390	COG4980	gas vesicle protein
NDR85_RS09395	COG2188	Transcriptional regulator
NDR85_RS09400	COG2814	Major facilitator Superfamily
NDR85_RS09405	COG0612	Peptidase, M16
NDR85_RS09410	COG0612	Peptidase, M16
NDR85_RS09415	COG0300	oxidoreductase activity
NDR85_RS09430	COG1426	Protein conserved in bacteria
NDR85_RS09435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NDR85_RS09440	COG1058	Belongs to the CinA family
NDR85_RS09440	COG1546	Belongs to the CinA family
NDR85_RS09445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NDR85_RS09450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDR85_RS09455	COG1418	mRNA catabolic process
NDR85_RS09460	COG1692	metallophosphoesterase
NDR85_RS09465	COG2359	stage V sporulation protein S
NDR85_RS09470	COG1063	alcohol dehydrogenase
NDR85_RS09475	COG0156	8-amino-7-oxononanoate synthase activity
NDR85_RS09480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NDR85_RS09485	COG4550	Control of competence regulator ComK, YlbF/YmcA
NDR85_RS09495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NDR85_RS09500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NDR85_RS09540	COG3226	Transcriptional regulator
NDR85_RS09545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS09550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDR85_RS09555	COG3321	synthase
NDR85_RS09560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NDR85_RS09560	COG2070	2-Nitropropane dioxygenase
NDR85_RS09565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS09570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NDR85_RS09575	COG3425	synthase
NDR85_RS09580	COG1024	Enoyl-CoA hydratase
NDR85_RS09585	COG1024	Enoyl-CoA hydratase
NDR85_RS09590	COG3321	synthase
NDR85_RS09590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS09590	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS09590	COG0300	oxidoreductase activity
NDR85_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS09595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS09595	COG3321	synthase
NDR85_RS09595	COG4221	oxidoreductase activity
NDR85_RS09595	COG0300	oxidoreductase activity
NDR85_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS09600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS09600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS09600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS09600	COG3321	synthase
NDR85_RS09605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS09605	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS09605	COG3321	synthase
NDR85_RS09605	COG4221	oxidoreductase activity
NDR85_RS09610	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NDR85_RS09610	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NDR85_RS09610	COG3321	synthase
NDR85_RS09610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS09615	COG2124	cytochrome p450
NDR85_RS09625	COG1404	Belongs to the peptidase S8 family
NDR85_RS09635	COG4195	phage-related replication protein
NDR85_RS09640	COG1764	response to oxidative stress
NDR85_RS09665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NDR85_RS09670	COG1923	regulation of RNA biosynthetic process
NDR85_RS09690	COG1780	Probably involved in ribonucleotide reductase function
NDR85_RS09695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDR85_RS09700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NDR85_RS09705	COG4112	unkown
NDR85_RS09710	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS09715	COG0464	growth
NDR85_RS09720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NDR85_RS09725	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NDR85_RS09730	COG0789	Transcriptional regulator
NDR85_RS09735	COG0174	glutamine synthetase
NDR85_RS09750	COG5444	nuclease activity
NDR85_RS09775	COG2273	Hydrolase Family 16
NDR85_RS09785	COG0457	Tetratricopeptide repeat
NDR85_RS09840	COG0726	polysaccharide deacetylase
NDR85_RS09875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NDR85_RS09880	COG2720	vancomycin resistance protein
NDR85_RS09885	COG3739	integral membrane protein
NDR85_RS09890	COG3655	Transcriptional regulator
NDR85_RS09900	COG2135	peptidase activity
NDR85_RS09905	COG5434	Belongs to the glycosyl hydrolase 28 family
NDR85_RS09925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NDR85_RS09935	COG3832	glyoxalase III activity
NDR85_RS09965	COG4195	phage-related replication protein
NDR85_RS09975	COG5577	PFAM Coat F domain
NDR85_RS09985	COG0346	lactoylglutathione lyase activity
NDR85_RS09995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NDR85_RS10000	COG1388	LysM domain
NDR85_RS10005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NDR85_RS10010	COG4224	UPF0291 protein
NDR85_RS10015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NDR85_RS10025	COG3763	UPF0154 protein
NDR85_RS10035	COG0785	Cytochrome C biogenesis protein
NDR85_RS10040	COG2201	protein-glutamate methylesterase activity
NDR85_RS10045	COG4846	Membrane protein involved in cytochrome C biogenesis
NDR85_RS10055	COG0071	Belongs to the small heat shock protein (HSP20) family
NDR85_RS10070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NDR85_RS10075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS10095	COG0824	Thioesterase
NDR85_RS10105	COG4841	protein insertion into membrane
NDR85_RS10110	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NDR85_RS10115	COG1832	CoA-binding protein
NDR85_RS10120	COG0187	DNA topoisomerase II activity
NDR85_RS10125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NDR85_RS10140	COG1115	amino acid carrier protein
NDR85_RS10145	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NDR85_RS10170	COG3507	Belongs to the glycosyl hydrolase 43 family
NDR85_RS10185	COG2246	polysaccharide biosynthetic process
NDR85_RS10190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NDR85_RS10195	COG0586	Pfam SNARE associated Golgi protein
NDR85_RS10200	COG2404	hydrolase activity, acting on ester bonds
NDR85_RS10205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NDR85_RS10210	COG1024	Enoyl-CoA hydratase
NDR85_RS10215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDR85_RS10220	COG0511	ligase activity, forming carbon-carbon bonds
NDR85_RS10225	COG0439	Biotin carboxylase
NDR85_RS10230	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS10235	COG1960	acyl-CoA dehydrogenase activity
NDR85_RS10250	COG1649	PFAM Uncharacterised BCR, COG1649
NDR85_RS10260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS10260	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NDR85_RS10265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS10270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS10275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS10280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS10285	COG2027	D-alanyl-D-alanine carboxypeptidase
NDR85_RS10290	COG2017	converts alpha-aldose to the beta-anomer
NDR85_RS10295	COG0534	Mate efflux family protein
NDR85_RS10310	COG0582	viral genome integration into host DNA
NDR85_RS10315	COG0166	Belongs to the GPI family
NDR85_RS10320	COG0405	Gamma-glutamyltransferase
NDR85_RS10325	COG0583	DNA-binding transcription factor activity
NDR85_RS10330	COG0604	alcohol dehydrogenase
NDR85_RS10335	COG0493	'glutamate synthase
NDR85_RS10340	COG0070	glutamate synthase
NDR85_RS10340	COG0069	glutamate synthase activity
NDR85_RS10340	COG0067	glutamate synthase
NDR85_RS10345	COG0583	DNA-binding transcription factor activity
NDR85_RS10350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NDR85_RS10370	COG0300	oxidoreductase activity
NDR85_RS10375	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NDR85_RS10385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS10400	COG1131	(ABC) transporter
NDR85_RS10410	COG2814	Major facilitator Superfamily
NDR85_RS10415	COG1070	Carbohydrate kinase
NDR85_RS10420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NDR85_RS10425	COG0243	molybdopterin cofactor binding
NDR85_RS10435	COG4305	rare lipoprotein A
NDR85_RS10440	COG3619	membrane
NDR85_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS10495	COG2814	Major facilitator Superfamily
NDR85_RS10505	COG1231	oxidoreductase activity
NDR85_RS10515	COG1070	Carbohydrate kinase
NDR85_RS10530	COG3507	Belongs to the glycosyl hydrolase 43 family
NDR85_RS10535	COG2211	Major facilitator Superfamily
NDR85_RS10560	COG3397	chitin binding
NDR85_RS10565	COG2318	DinB family
NDR85_RS10575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NDR85_RS10605	COG0457	Tetratricopeptide repeat
NDR85_RS10620	COG0574	Belongs to the PEP-utilizing enzyme family
NDR85_RS10620	COG3848	Pyruvate phosphate dikinase
NDR85_RS10630	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS10635	COG1733	regulation of RNA biosynthetic process
NDR85_RS10640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDR85_RS10645	COG0662	Cupin 2, conserved barrel domain protein
NDR85_RS10645	COG2207	Transcriptional regulator
NDR85_RS10650	COG0456	acetyltransferase
NDR85_RS10655	COG1309	transcriptional regulator
NDR85_RS10660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS10665	COG3708	Transcriptional regulator
NDR85_RS10670	COG2378	regulation of single-species biofilm formation
NDR85_RS10680	COG0640	Transcriptional regulator
NDR85_RS10685	COG0741	lytic transglycosylase activity
NDR85_RS10690	COG2322	membrane
NDR85_RS10705	COG1619	proteins homologs of microcin C7 resistance protein MccF
NDR85_RS10710	COG3239	Fatty acid desaturase
NDR85_RS10715	COG4585	Histidine kinase
NDR85_RS10720	COG2197	response regulator
NDR85_RS10740	COG3584	3D domain protein
NDR85_RS10740	COG1388	LysM domain
NDR85_RS10745	COG0514	ATP-dependent DNA helicase (RecQ)
NDR85_RS10755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDR85_RS10760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NDR85_RS10775	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS10780	COG1657	PFAM Prenyltransferase squalene oxidase
NDR85_RS10785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDR85_RS10790	COG0733	neurotransmitter:sodium symporter activity
NDR85_RS10800	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDR85_RS10805	COG0567	Dehydrogenase, E1 component
NDR85_RS10810	COG4548	von Willebrand factor, type A
NDR85_RS10815	COG0714	Associated with various cellular activities
NDR85_RS10820	COG2032	superoxide dismutase activity
NDR85_RS10825	COG0791	NLP P60 protein
NDR85_RS10825	COG1388	LysM domain
NDR85_RS10830	COG1819	glycosyl
NDR85_RS10835	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NDR85_RS10840	COG0534	Mate efflux family protein
NDR85_RS10845	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS10850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NDR85_RS10855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NDR85_RS10865	COG2962	Rard protein
NDR85_RS10880	COG1942	4-Oxalocrotonate Tautomerase
NDR85_RS10890	COG1733	regulation of RNA biosynthetic process
NDR85_RS10895	COG0778	Nitroreductase
NDR85_RS10900	COG0400	carboxylic ester hydrolase activity
NDR85_RS10905	COG0346	lactoylglutathione lyase activity
NDR85_RS10915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDR85_RS10920	COG0793	Belongs to the peptidase S41A family
NDR85_RS10920	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS10925	COG2226	methyltransferase
NDR85_RS10935	COG1876	peptidase activity
NDR85_RS10940	COG0813	purine-nucleoside phosphorylase activity
NDR85_RS10950	COG1309	transcriptional regulator
NDR85_RS10955	COG2814	Major facilitator Superfamily
NDR85_RS10975	COG0671	phosphoesterase, PA-phosphatase related
NDR85_RS10995	COG4479	Belongs to the UPF0346 family
NDR85_RS11005	COG1509	lysine 2,3-aminomutase activity
NDR85_RS11010	COG0456	acetyltransferase
NDR85_RS11015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDR85_RS11020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDR85_RS11025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDR85_RS11030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDR85_RS11040	COG0456	acetyltransferase
NDR85_RS11045	COG0463	Glycosyl transferase, family 2
NDR85_RS11060	COG4641	Protein conserved in bacteria
NDR85_RS11065	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NDR85_RS11070	COG1086	Polysaccharide biosynthesis protein
NDR85_RS11080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NDR85_RS11085	COG1846	Transcriptional regulator
NDR85_RS11090	COG0534	Mate efflux family protein
NDR85_RS11100	COG4698	Protein conserved in bacteria
NDR85_RS11105	COG2755	lipolytic protein G-D-S-L family
NDR85_RS11110	COG1999	signal sequence binding
NDR85_RS11120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NDR85_RS11125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NDR85_RS11130	COG1272	protein, Hemolysin III
NDR85_RS11135	COG0204	Acyl-transferase
NDR85_RS11140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NDR85_RS11150	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NDR85_RS11160	COG2521	methyltransferase
NDR85_RS11160	COG2136	Putative SAM-dependent methyltransferase
NDR85_RS11170	COG0129	dihydroxy-acid dehydratase activity
NDR85_RS11175	COG1413	lyase activity
NDR85_RS11180	COG1418	mRNA catabolic process
NDR85_RS11185	COG0386	Belongs to the glutathione peroxidase family
NDR85_RS11190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NDR85_RS11195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NDR85_RS11205	COG1278	Cold shock
NDR85_RS11225	COG0328	RNA-DNA hybrid ribonuclease activity
NDR85_RS11230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NDR85_RS11235	COG0328	RNA-DNA hybrid ribonuclease activity
NDR85_RS11245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDR85_RS11260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NDR85_RS11270	COG1755	Isoprenylcysteine carboxyl methyltransferase
NDR85_RS11275	COG3424	synthase
NDR85_RS11280	COG2233	PERMEase
NDR85_RS11285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NDR85_RS11290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NDR85_RS11300	COG0800	Aldolase
NDR85_RS11305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDR85_RS11310	COG1609	Transcriptional regulator
NDR85_RS11315	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NDR85_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS11325	COG1199	ATP-dependent helicase activity
NDR85_RS11340	COG0116	Belongs to the methyltransferase superfamily
NDR85_RS11355	COG4474	Belongs to the UPF0398 family
NDR85_RS11370	COG3359	exonuclease
NDR85_RS11375	COG1111	helicase
NDR85_RS11375	COG1205	dead DEAH box helicase
NDR85_RS11380	COG2190	(PTS) system
NDR85_RS11385	COG0071	Belongs to the small heat shock protein (HSP20) family
NDR85_RS11420	COG3331	DNA recombination
NDR85_RS11425	COG4499	WXG100 protein secretion system (Wss), protein YukC
NDR85_RS11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDR85_RS11435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NDR85_RS11440	COG3935	DnaD domain protein
NDR85_RS11445	COG0017	Asparaginyl-tRNA synthetase
NDR85_RS11450	COG0436	Aminotransferase
NDR85_RS11455	COG5353	protein conserved in bacteria
NDR85_RS11465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NDR85_RS11465	COG1199	ATP-dependent helicase activity
NDR85_RS11470	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NDR85_RS11475	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NDR85_RS11480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NDR85_RS11485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NDR85_RS11485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NDR85_RS11490	COG0617	tRNA 3'-terminal CCA addition
NDR85_RS11495	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS11500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NDR85_RS11505	COG1803	Methylglyoxal synthase
NDR85_RS11510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NDR85_RS11515	COG1694	Mazg nucleotide pyrophosphohydrolase
NDR85_RS11520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS11530	COG4347	Protein of unknown function (DUF1405)
NDR85_RS11535	COG2010	Cytochrome c
NDR85_RS11535	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NDR85_RS11540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NDR85_RS11545	COG0723	plastoquinol--plastocyanin reductase activity
NDR85_RS11555	COG5582	Belongs to the UPF0302 family
NDR85_RS11560	COG0457	Tetratricopeptide repeat
NDR85_RS11565	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NDR85_RS11570	COG0287	Prephenate dehydrogenase
NDR85_RS11575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NDR85_RS11580	COG0159	tryptophan synthase activity
NDR85_RS11585	COG0133	tryptophan synthase activity
NDR85_RS11590	COG0135	phosphoribosylanthranilate isomerase activity
NDR85_RS11600	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NDR85_RS11605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NDR85_RS11610	COG4401	Chorismate mutase type I
NDR85_RS11615	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NDR85_RS11620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NDR85_RS11625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NDR85_RS11630	COG0105	UTP biosynthetic process
NDR85_RS11635	COG0142	geranyltranstransferase activity
NDR85_RS11640	COG2226	methyltransferase
NDR85_RS11645	COG0142	geranyltranstransferase activity
NDR85_RS11655	COG0302	gtp cyclohydrolase
NDR85_RS11660	COG0776	regulation of translation
NDR85_RS11665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NDR85_RS11680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NDR85_RS11685	COG1160	GTP binding
NDR85_RS11710	COG1304	FMN binding
NDR85_RS11715	COG0539	negative regulation of cytoplasmic translation
NDR85_RS11720	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NDR85_RS11730	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NDR85_RS11735	COG2959	enzyme of heme biosynthesis
NDR85_RS11740	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS11740	COG3773	Cell wall hydrolase
NDR85_RS11745	COG2339	peptidase activity
NDR85_RS11750	COG0492	ferredoxin-NADP+ reductase activity
NDR85_RS11755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NDR85_RS11760	COG4862	establishment of competence for transformation
NDR85_RS11765	COG1408	metallophosphoesterase
NDR85_RS11775	COG1388	LysM domain
NDR85_RS11780	COG1266	CAAX protease self-immunity
NDR85_RS11785	COG0514	ATP-dependent DNA helicase (RecQ)
NDR85_RS11790	COG4955	Helix-turn-helix domain
NDR85_RS11795	COG1141	Ferredoxin
NDR85_RS11800	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NDR85_RS11805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NDR85_RS11810	COG0710	3-dehydroquinate dehydratase activity
NDR85_RS11820	COG1595	DNA-templated transcription, initiation
NDR85_RS11825	COG5002	protein histidine kinase activity
NDR85_RS11830	COG0745	RESPONSE REGULATOR receiver
NDR85_RS11835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NDR85_RS11840	COG1333	cytochrome c biogenesis protein
NDR85_RS11845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS11850	COG1187	pseudouridine synthase activity
NDR85_RS11855	COG0700	Nucleoside recognition
NDR85_RS11860	COG2715	membrane protein required for spore maturation
NDR85_RS11865	COG1686	Belongs to the peptidase S11 family
NDR85_RS11875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NDR85_RS11880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NDR85_RS11890	COG1547	Domain of unknown function (DUF309)
NDR85_RS11895	COG0456	acetyltransferase
NDR85_RS11900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NDR85_RS11905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDR85_RS11905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NDR85_RS11910	COG0307	riboflavin synthase, alpha
NDR85_RS11915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDR85_RS11915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NDR85_RS11925	COG0681	Belongs to the peptidase S26 family
NDR85_RS11930	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NDR85_RS11935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NDR85_RS11940	COG4086	secreted protein
NDR85_RS11945	COG0019	diaminopimelate decarboxylase activity
NDR85_RS11950	COG0697	spore germination
NDR85_RS11965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NDR85_RS11985	COG1191	sigma factor activity
NDR85_RS11990	COG2172	sigma factor antagonist activity
NDR85_RS11995	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS12000	COG1686	Belongs to the peptidase S11 family
NDR85_RS12005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NDR85_RS12010	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NDR85_RS12015	COG4974	Belongs to the 'phage' integrase family
NDR85_RS12025	COG0735	belongs to the Fur family
NDR85_RS12030	COG1300	Membrane
NDR85_RS12040	COG0281	malic enzyme
NDR85_RS12045	COG1757	Na H antiporter
NDR85_RS12050	COG1027	Aspartate ammonia-lyase
NDR85_RS12055	COG0252	asparaginase activity
NDR85_RS12060	COG1396	sequence-specific DNA binding
NDR85_RS12065	COG1379	DNA repair
NDR85_RS12070	COG0494	nUDIX hydrolase
NDR85_RS12080	COG0667	Aldo Keto reductase
NDR85_RS12090	COG1073	alpha beta
NDR85_RS12100	COG4918	Iron-sulphur cluster biosynthesis
NDR85_RS12105	COG0456	acetyltransferase
NDR85_RS12105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NDR85_RS12115	COG0456	acetyltransferase
NDR85_RS12125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDR85_RS12135	COG2211	Major facilitator Superfamily
NDR85_RS12150	COG1072	(Pantothenic acid kinase))
NDR85_RS12155	COG3048	D-serine ammonia-lyase activity
NDR85_RS12160	COG0300	oxidoreductase activity
NDR85_RS12165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS12170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDR85_RS12175	COG4187	Peptidase family M20/M25/M40
NDR85_RS12180	COG1902	pentaerythritol trinitrate reductase activity
NDR85_RS12185	COG0596	Alpha beta hydrolase
NDR85_RS12195	COG1234	tRNA 3'-trailer cleavage
NDR85_RS12200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NDR85_RS12210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NDR85_RS12215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NDR85_RS12225	COG0706	membrane insertase activity
NDR85_RS12230	COG3361	conserved protein (COG2071)
NDR85_RS12235	COG2195	Cleaves the N-terminal amino acid of tripeptides
NDR85_RS12240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NDR85_RS12245	COG0346	lactoylglutathione lyase activity
NDR85_RS12255	COG1376	ErfK ybiS ycfS ynhG family protein
NDR85_RS12260	COG4129	membrane
NDR85_RS12265	COG1126	abc transporter atp-binding protein
NDR85_RS12270	COG0765	amino acid transport
NDR85_RS12275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDR85_RS12285	COG1597	lipid kinase activity
NDR85_RS12290	COG2814	Major facilitator Superfamily
NDR85_RS12295	COG0789	Transcriptional regulator
NDR85_RS12295	COG4978	Transcriptional regulator
NDR85_RS12300	COG0508	dehydrogenase complex catalyzes the overall conversion of
NDR85_RS12305	COG0022	dehydrogenase e1 component
NDR85_RS12310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NDR85_RS12315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NDR85_RS12320	COG3426	butyrate kinase activity
NDR85_RS12325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NDR85_RS12330	COG0280	phosphate acetyltransferase
NDR85_RS12335	COG3290	protein histidine kinase activity
NDR85_RS12335	COG3829	transcription factor binding
NDR85_RS12345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NDR85_RS12350	COG2079	MmgE PrpD family protein
NDR85_RS12355	COG0372	Belongs to the citrate synthase family
NDR85_RS12360	COG1960	acyl-CoA dehydrogenase activity
NDR85_RS12365	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDR85_RS12370	COG0183	Belongs to the thiolase family
NDR85_RS12375	COG0584	glycerophosphoryl diester phosphodiesterase
NDR85_RS12380	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS12395	COG1902	pentaerythritol trinitrate reductase activity
NDR85_RS12400	COG0745	RESPONSE REGULATOR receiver
NDR85_RS12405	COG0750	zinc metalloprotease
NDR85_RS12410	COG0497	DNA recombination
NDR85_RS12415	COG1438	arginine binding
NDR85_RS12420	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NDR85_RS12425	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NDR85_RS12430	COG0142	geranyltranstransferase activity
NDR85_RS12435	COG1722	exodeoxyribonuclease VII activity
NDR85_RS12440	COG1570	exodeoxyribonuclease VII activity
NDR85_RS12445	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NDR85_RS12450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NDR85_RS12455	COG1302	Protein conserved in bacteria
NDR85_RS12460	COG0439	Biotin carboxylase
NDR85_RS12465	COG0511	ligase activity, forming carbon-carbon bonds
NDR85_RS12505	COG3854	ATPases associated with a variety of cellular activities
NDR85_RS12515	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NDR85_RS12520	COG0006	proline dipeptidase activity
NDR85_RS12525	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NDR85_RS12535	COG3872	metal-dependent enzyme
NDR85_RS12545	COG1752	Esterase of the alpha-beta hydrolase superfamily
NDR85_RS12550	COG1321	iron dependent repressor
NDR85_RS12555	COG0095	Lipoate-protein ligase
NDR85_RS12560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDR85_RS12565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDR85_RS12570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NDR85_RS12575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NDR85_RS12580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDR85_RS12595	COG1396	sequence-specific DNA binding
NDR85_RS12605	COG0681	Belongs to the peptidase S26 family
NDR85_RS12630	COG4940	Competence protein ComGF
NDR85_RS12640	COG4970	Tfp pilus assembly protein FimT
NDR85_RS12645	COG4537	Required for transformation and DNA binding
NDR85_RS12650	COG1459	type II secretion system
NDR85_RS12655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NDR85_RS12660	COG0517	IMP dehydrogenase activity
NDR85_RS12665	COG0598	Magnesium transport protein CorA
NDR85_RS12675	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS12685	COG1393	Belongs to the ArsC family
NDR85_RS12695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS12705	COG0011	TIGRFAM Protein of
NDR85_RS12715	COG2866	Carboxypeptidase
NDR85_RS12725	COG1940	carbohydrate kinase activity
NDR85_RS12730	COG4483	Protein conserved in bacteria
NDR85_RS12735	COG0705	Rhomboid family
NDR85_RS12735	COG0457	Tetratricopeptide repeat
NDR85_RS12745	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NDR85_RS12755	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS12770	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDR85_RS12775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NDR85_RS12780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NDR85_RS12785	COG0581	inorganic phosphate transmembrane transporter activity
NDR85_RS12790	COG0573	inorganic phosphate transmembrane transporter activity
NDR85_RS12795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NDR85_RS12800	COG0768	penicillin binding
NDR85_RS12805	COG0477	Major facilitator Superfamily
NDR85_RS12810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NDR85_RS12815	COG2839	Protein conserved in bacteria
NDR85_RS12820	COG5521	maltodextrose utilization protein MalA
NDR85_RS12835	COG1388	LysM domain
NDR85_RS12840	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NDR85_RS12845	COG4709	membrane
NDR85_RS12850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NDR85_RS12855	COG0735	belongs to the Fur family
NDR85_RS12860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS12870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NDR85_RS12875	COG0513	Belongs to the DEAD box helicase family
NDR85_RS12885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NDR85_RS12890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NDR85_RS12895	COG2384	SAM-dependent methyltransferase
NDR85_RS12900	COG2010	Cytochrome c
NDR85_RS12905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NDR85_RS12910	COG0358	DNA primase activity
NDR85_RS12915	COG1671	Belongs to the UPF0178 family
NDR85_RS12920	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NDR85_RS12925	COG0517	IMP dehydrogenase activity
NDR85_RS12930	COG0751	glycine-tRNA ligase activity
NDR85_RS12935	COG0752	glycyl-tRNA synthetase alpha subunit
NDR85_RS12940	COG1381	Involved in DNA repair and RecF pathway recombination
NDR85_RS12950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NDR85_RS12955	COG0295	cytidine deaminase activity
NDR85_RS12960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NDR85_RS12965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NDR85_RS12970	COG1480	7TM receptor with intracellular HD hydrolase
NDR85_RS12975	COG1702	phosphate starvation-inducible protein PhoH
NDR85_RS12980	COG0561	phosphatase activity
NDR85_RS12995	COG4864	UPF0365 protein
NDR85_RS13000	COG1030	water channel activity
NDR85_RS13005	COG1610	YqeY-like protein
NDR85_RS13015	COG1283	sodium-dependent phosphate transmembrane transporter activity
NDR85_RS13020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NDR85_RS13025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NDR85_RS13030	COG2264	protein methyltransferase activity
NDR85_RS13035	COG0484	heat shock protein binding
NDR85_RS13045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NDR85_RS13050	COG1420	regulation of RNA biosynthetic process
NDR85_RS13055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NDR85_RS13060	COG0481	GTPase activity
NDR85_RS13070	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS13075	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NDR85_RS13085	COG1466	dna polymerase III delta subunit
NDR85_RS13100	COG0658	competence protein
NDR85_RS13100	COG2333	competence protein COMEC
NDR85_RS13105	COG2131	deaminase
NDR85_RS13110	COG1596	polysaccharide export
NDR85_RS13110	COG1555	photosystem II stabilization
NDR85_RS13115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NDR85_RS13120	COG2226	methyltransferase
NDR85_RS13125	COG0799	negative regulation of ribosome biogenesis
NDR85_RS13130	COG1713	HD superfamily hydrolase involved in NAD metabolism
NDR85_RS13135	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NDR85_RS13140	COG1534	Rna-binding protein
NDR85_RS13145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NDR85_RS13150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NDR85_RS13155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NDR85_RS13170	COG2755	lipolytic protein G-D-S-L family
NDR85_RS13175	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS13175	COG5632	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS13180	COG0398	Pfam SNARE associated Golgi protein
NDR85_RS13185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
NDR85_RS13200	COG3209	COG3209 Rhs family protein
NDR85_RS13220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDR85_RS13225	COG0798	PFAM Bile acid sodium symporter
NDR85_RS13230	COG0346	lactoylglutathione lyase activity
NDR85_RS13235	COG0640	Transcriptional regulator
NDR85_RS13255	COG0604	alcohol dehydrogenase
NDR85_RS13265	COG2315	Protein conserved in bacteria
NDR85_RS13270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NDR85_RS13275	COG0457	Tetratricopeptide repeat
NDR85_RS13280	COG5444	nuclease activity
NDR85_RS13290	COG5632	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS13290	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS13290	COG1388	LysM domain
NDR85_RS13295	COG4824	toxin secretion phage lysis holin
NDR85_RS13310	COG1794	racemase activity, acting on amino acids and derivatives
NDR85_RS13330	COG0563	adenylate kinase activity
NDR85_RS13365	COG3223	Belongs to the PsiE family
NDR85_RS13370	COG5002	protein histidine kinase activity
NDR85_RS13370	COG0642	Histidine kinase
NDR85_RS13375	COG0745	RESPONSE REGULATOR receiver
NDR85_RS13380	COG2311	Membrane
NDR85_RS13385	COG0454	-acetyltransferase
NDR85_RS13390	COG2732	(Barnase) inhibitor
NDR85_RS13415	COG1725	Transcriptional regulator
NDR85_RS13460	COG3443	Belongs to the bacterial solute-binding protein 9 family
NDR85_RS13470	COG2851	Citrate transporter
NDR85_RS13475	COG0583	DNA-binding transcription factor activity
NDR85_RS13480	COG2828	Protein conserved in bacteria
NDR85_RS13485	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS13490	COG5566	PFAM Mor transcription activator
NDR85_RS13495	COG0596	Alpha beta hydrolase
NDR85_RS13500	COG0697	spore germination
NDR85_RS13510	COG4991	sh3 domain protein
NDR85_RS13515	COG4991	sh3 domain protein
NDR85_RS13540	COG0693	protein deglycase activity
NDR85_RS13550	COG3716	PTS system mannose fructose sorbose family IID component
NDR85_RS13555	COG3715	PTS system
NDR85_RS13560	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS13565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS13570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NDR85_RS13570	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NDR85_RS13575	COG1113	amino acid transport
NDR85_RS13580	COG1280	lysine exporter protein (LysE YggA)
NDR85_RS13585	COG1378	Sugar-specific transcriptional regulator TrmB
NDR85_RS13590	COG1595	DNA-templated transcription, initiation
NDR85_RS13600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NDR85_RS13600	COG2755	lipolytic protein G-D-S-L family
NDR85_RS13610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDR85_RS13610	COG2124	cytochrome p450
NDR85_RS13615	COG1309	transcriptional regulator
NDR85_RS13635	COG2116	formate transmembrane transporter activity
NDR85_RS13640	COG5609	conserved protein (DUF2294)
NDR85_RS13645	COG3383	formate dehydrogenase (NAD+) activity
NDR85_RS13650	COG2427	Protein of unknown function (DUF1641)
NDR85_RS13660	COG0626	cystathionine gamma-synthase activity
NDR85_RS13670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NDR85_RS13675	COG2226	methyltransferase
NDR85_RS13690	COG0768	penicillin binding
NDR85_RS13695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NDR85_RS13700	COG0572	uridine kinase
NDR85_RS13705	COG0826	peptidase U32
NDR85_RS13710	COG0826	peptidase U32
NDR85_RS13715	COG4122	O-methyltransferase activity
NDR85_RS13720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NDR85_RS13725	COG3906	Belongs to the UPF0473 family
NDR85_RS13730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NDR85_RS13735	COG4472	Bacterial protein of unknown function (DUF965)
NDR85_RS13740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NDR85_RS13745	COG0628	permease
NDR85_RS13750	COG1126	abc transporter atp-binding protein
NDR85_RS13755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDR85_RS13760	COG0765	amino acid transport
NDR85_RS13765	COG0765	amino acid transport
NDR85_RS13780	COG3881	PFAM PRC-barrel domain
NDR85_RS13785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NDR85_RS13790	COG0457	Tetratricopeptide repeat
NDR85_RS13795	COG0482	sulfurtransferase activity
NDR85_RS13800	COG1104	cysteine desulfurase activity
NDR85_RS13805	COG1959	2 iron, 2 sulfur cluster binding
NDR85_RS13810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NDR85_RS13815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NDR85_RS13825	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NDR85_RS13830	COG0124	histidyl-tRNA synthetase
NDR85_RS13840	COG4991	sh3 domain protein
NDR85_RS13840	COG3103	Sh3 type 3 domain protein
NDR85_RS13840	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS13845	COG1490	D-aminoacyl-tRNA deacylase activity
NDR85_RS13850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NDR85_RS13855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NDR85_RS13860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NDR85_RS13860	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NDR85_RS13865	COG5416	Lipopolysaccharide assembly protein A domain
NDR85_RS13870	COG0490	domain, Protein
NDR85_RS13875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NDR85_RS13875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NDR85_RS13885	COG2244	polysaccharide biosynthetic process
NDR85_RS13890	COG2323	membrane
NDR85_RS13900	COG1862	Preprotein translocase
NDR85_RS13905	COG0343	queuine tRNA-ribosyltransferase activity
NDR85_RS13910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NDR85_RS13920	COG2255	four-way junction helicase activity
NDR85_RS13925	COG0632	four-way junction helicase activity
NDR85_RS13935	COG2814	Major facilitator Superfamily
NDR85_RS13940	COG0673	inositol 2-dehydrogenase activity
NDR85_RS13945	COG2112	serine threonine protein kinase
NDR85_RS13960	COG1115	amino acid carrier protein
NDR85_RS13965	COG0217	transcriptional regulatory protein
NDR85_RS13975	COG1388	LysM domain
NDR85_RS13980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NDR85_RS13985	COG0157	Belongs to the NadC ModD family
NDR85_RS13990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NDR85_RS13995	COG1104	cysteine desulfurase activity
NDR85_RS14000	COG1827	regulation of RNA biosynthetic process
NDR85_RS14005	COG0077	Prephenate dehydratase
NDR85_RS14010	COG4492	Belongs to the UPF0735 family
NDR85_RS14015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NDR85_RS14020	COG3290	protein histidine kinase activity
NDR85_RS14030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NDR85_RS14035	COG2868	ribosomal protein
NDR85_RS14040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NDR85_RS14045	COG1994	Peptidase M50
NDR85_RS14050	COG0739	heme binding
NDR85_RS14055	COG2894	cell division
NDR85_RS14060	COG0850	regulation of cytokinetic process
NDR85_RS14065	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NDR85_RS14075	COG1077	Cell shape determining protein MreB Mrl
NDR85_RS14080	COG2003	Belongs to the UPF0758 family
NDR85_RS14085	COG0424	maF-like protein
NDR85_RS14095	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NDR85_RS14100	COG0285	dihydrofolate synthase activity
NDR85_RS14105	COG0525	valine-tRNA ligase activity
NDR85_RS14115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NDR85_RS14120	COG1388	LysM domain
NDR85_RS14125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NDR85_RS14130	COG0113	porphobilinogen synthase activity
NDR85_RS14135	COG1587	Uroporphyrinogen-III synthase
NDR85_RS14140	COG0181	hydroxymethylbilane synthase activity
NDR85_RS14145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NDR85_RS14150	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NDR85_RS14160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NDR85_RS14165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NDR85_RS14170	COG1067	ATP-dependent peptidase activity
NDR85_RS14170	COG0470	DNA polymerase III
NDR85_RS14175	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NDR85_RS14180	COG0544	peptidyl-prolyl cis-trans isomerase activity
NDR85_RS14185	COG0457	Tetratricopeptide repeat
NDR85_RS14185	COG1477	protein flavinylation
NDR85_RS14190	COG0066	3-isopropylmalate dehydratase activity
NDR85_RS14195	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NDR85_RS14200	COG0473	3-isopropylmalate dehydrogenase activity
NDR85_RS14205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NDR85_RS14210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NDR85_RS14215	COG0440	acetolactate synthase activity
NDR85_RS14220	COG0028	Belongs to the TPP enzyme family
NDR85_RS14230	COG0454	-acetyltransferase
NDR85_RS14240	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NDR85_RS14250	COG0622	Phosphoesterase
NDR85_RS14255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NDR85_RS14260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NDR85_RS14265	COG5401	PFAM Sporulation and spore germination
NDR85_RS14270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NDR85_RS14275	COG1846	Transcriptional regulator
NDR85_RS14280	COG2197	response regulator
NDR85_RS14285	COG0824	Thioesterase
NDR85_RS14290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NDR85_RS14295	COG1053	succinate dehydrogenase
NDR85_RS14300	COG2009	succinate dehydrogenase
NDR85_RS14305	COG1719	4-vinyl reductase, 4VR
NDR85_RS14310	COG0527	aspartate kinase activity
NDR85_RS14315	COG0322	excinuclease ABC activity
NDR85_RS14320	COG3118	belongs to the thioredoxin family
NDR85_RS14325	COG3534	alpha-L-arabinofuranosidase
NDR85_RS14330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NDR85_RS14340	COG1024	Enoyl-CoA hydratase
NDR85_RS14345	COG1309	transcriptional regulator
NDR85_RS14350	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS14355	COG3766	membrane
NDR85_RS14360	COG1193	negative regulation of DNA recombination
NDR85_RS14365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NDR85_RS14365	COG1796	DNA polymerase
NDR85_RS14370	COG1286	toxin biosynthetic process
NDR85_RS14375	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NDR85_RS14380	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NDR85_RS14385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDR85_RS14385	COG0072	phenylalanine-tRNA ligase activity
NDR85_RS14390	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NDR85_RS14400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NDR85_RS14415	COG0277	FAD linked oxidase domain protein
NDR85_RS14420	COG0247	lactate metabolic process
NDR85_RS14425	COG0346	lactoylglutathione lyase activity
NDR85_RS14430	COG1966	Carbon starvation protein
NDR85_RS14445	COG1695	Transcriptional regulator
NDR85_RS14450	COG3534	alpha-L-arabinofuranosidase
NDR85_RS14455	COG0395	ABC-type sugar transport system, permease component
NDR85_RS14460	COG1175	transmembrane transport
NDR85_RS14465	COG1653	transport
NDR85_RS14470	COG0371	Dehydrogenase
NDR85_RS14475	COG0647	UMP catabolic process
NDR85_RS14480	COG0235	Class ii aldolase
NDR85_RS14485	COG1069	ribulokinase activity
NDR85_RS14490	COG2160	L-arabinose isomerase activity
NDR85_RS14495	COG3507	Belongs to the glycosyl hydrolase 43 family
NDR85_RS14500	COG1363	Peptidase, m42
NDR85_RS14510	COG3326	Membrane
NDR85_RS14515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NDR85_RS14520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NDR85_RS14525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NDR85_RS14540	COG1346	cytolysis
NDR85_RS14545	COG1380	Effector of murein hydrolase LrgA
NDR85_RS14550	COG3279	Response regulator of the LytR AlgR family
NDR85_RS14560	COG1011	Hydrolase
NDR85_RS14565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDR85_RS14575	COG0398	Pfam SNARE associated Golgi protein
NDR85_RS14580	COG1484	DNA-dependent DNA replication
NDR85_RS14585	COG3611	Membrane attachment protein
NDR85_RS14590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NDR85_RS14595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NDR85_RS14600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NDR85_RS14605	COG1733	regulation of RNA biosynthetic process
NDR85_RS14610	COG2814	Major facilitator Superfamily
NDR85_RS14615	COG0656	L-ascorbic acid biosynthetic process
NDR85_RS14620	COG0237	dephospho-CoA kinase activity
NDR85_RS14630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NDR85_RS14635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDR85_RS14635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NDR85_RS14640	COG5002	protein histidine kinase activity
NDR85_RS14645	COG0745	RESPONSE REGULATOR receiver
NDR85_RS14650	COG0039	L-malate dehydrogenase activity
NDR85_RS14655	COG0538	isocitrate dehydrogenase activity
NDR85_RS14660	COG0372	Belongs to the citrate synthase family
NDR85_RS14665	COG2707	UPF0756 membrane protein
NDR85_RS14670	COG0628	permease
NDR85_RS14675	COG3030	protein affecting phage T7 exclusion by the F plasmid
NDR85_RS14680	COG0469	pyruvate kinase activity
NDR85_RS14685	COG0205	6-phosphofructokinase activity
NDR85_RS14690	COG0825	malonyl-CoA metabolic process
NDR85_RS14695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NDR85_RS14700	COG0281	malic enzyme
NDR85_RS14705	COG0587	DNA-directed DNA polymerase activity
NDR85_RS14725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NDR85_RS14735	COG4109	DRTGG domain
NDR85_RS14740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NDR85_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS14755	COG0165	Argininosuccinate lyase
NDR85_RS14760	COG0137	argininosuccinate synthase activity
NDR85_RS14765	COG0521	Mo-molybdopterin cofactor biosynthetic process
NDR85_RS14770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NDR85_RS14775	COG0827	DNA restriction-modification system
NDR85_RS14780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NDR85_RS14785	COG3874	Sporulation protein YtfJ
NDR85_RS14795	COG1714	RDD family
NDR85_RS14800	COG0616	signal peptide processing
NDR85_RS14805	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NDR85_RS14810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NDR85_RS14815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NDR85_RS14825	COG0301	tRNA thio-modification
NDR85_RS14830	COG1104	cysteine desulfurase activity
NDR85_RS14835	COG1114	Component of the transport system for branched-chain amino acids
NDR85_RS14840	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NDR85_RS14845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NDR85_RS14850	COG1309	transcriptional regulator
NDR85_RS14855	COG1956	GAF domain-containing protein
NDR85_RS14860	COG2199	diguanylate cyclase activity
NDR85_RS14860	COG2203	Gaf domain
NDR85_RS14875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDR85_RS14880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NDR85_RS14885	COG0454	-acetyltransferase
NDR85_RS14890	COG0517	IMP dehydrogenase activity
NDR85_RS14895	COG0123	including yeast histone deacetylase and acetoin utilization protein
NDR85_RS14900	COG1360	Flagellar Motor Protein
NDR85_RS14905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NDR85_RS14910	COG1609	Transcriptional regulator
NDR85_RS14915	COG1605	Chorismate mutase
NDR85_RS14915	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NDR85_RS14920	COG3118	belongs to the thioredoxin family
NDR85_RS14925	COG4980	gas vesicle protein
NDR85_RS14930	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NDR85_RS14935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NDR85_RS14940	COG1674	ftsk spoiiie
NDR85_RS14945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NDR85_RS14950	COG4848	Belongs to the UPF0354 family
NDR85_RS14955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS14970	COG1363	Peptidase, m42
NDR85_RS14975	COG5584	Small secreted protein
NDR85_RS14980	COG0281	malic enzyme
NDR85_RS14985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS14990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NDR85_RS15000	COG0510	thiamine kinase activity
NDR85_RS15005	COG1523	belongs to the glycosyl hydrolase 13 family
NDR85_RS15010	COG1597	lipid kinase activity
NDR85_RS15020	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NDR85_RS15025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NDR85_RS15030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDR85_RS15035	COG2252	PERMEase
NDR85_RS15040	COG4473	ABC transporter
NDR85_RS15045	COG1131	(ABC) transporter
NDR85_RS15050	COG1349	DNA-binding transcription factor activity
NDR85_RS15055	COG1187	pseudouridine synthase activity
NDR85_RS15060	COG2244	polysaccharide biosynthetic process
NDR85_RS15065	COG2081	HI0933 family
NDR85_RS15070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NDR85_RS15080	COG5578	integral membrane protein
NDR85_RS15085	COG0673	inositol 2-dehydrogenase activity
NDR85_RS15090	COG1653	transport
NDR85_RS15095	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NDR85_RS15100	COG4209	transmembrane transport
NDR85_RS15105	COG2207	Transcriptional regulator
NDR85_RS15110	COG1653	transport
NDR85_RS15115	COG0395	ABC-type sugar transport system, permease component
NDR85_RS15120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS15125	COG2124	cytochrome p450
NDR85_RS15130	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NDR85_RS15140	COG0156	8-amino-7-oxononanoate synthase activity
NDR85_RS15145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NDR85_RS15155	COG1073	alpha beta
NDR85_RS15160	COG1609	Transcriptional regulator
NDR85_RS15165	COG1653	transport
NDR85_RS15170	COG1175	transmembrane transport
NDR85_RS15175	COG0395	ABC-type sugar transport system, permease component
NDR85_RS15180	COG1486	melibiose metabolic process
NDR85_RS15185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NDR85_RS15190	COG0495	leucyl-tRNA aminoacylation
NDR85_RS15200	COG1366	Belongs to the anti-sigma-factor antagonist family
NDR85_RS15200	COG2202	Pas domain
NDR85_RS15205	COG2814	Major facilitator Superfamily
NDR85_RS15210	COG2433	Pfam Transposase IS66
NDR85_RS15215	COG0577	efflux transmembrane transporter activity
NDR85_RS15220	COG1136	(ABC) transporter
NDR85_RS15225	COG2205	protein histidine kinase activity
NDR85_RS15230	COG0745	RESPONSE REGULATOR receiver
NDR85_RS15235	COG0577	efflux transmembrane transporter activity
NDR85_RS15240	COG1136	(ABC) transporter
NDR85_RS15255	COG1131	(ABC) transporter
NDR85_RS15260	COG1725	Transcriptional regulator
NDR85_RS15275	COG1242	4 iron, 4 sulfur cluster binding
NDR85_RS15280	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NDR85_RS15290	COG2267	carboxylic ester hydrolase activity
NDR85_RS15295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NDR85_RS15300	COG1113	amino acid transport
NDR85_RS15305	COG0367	asparagine synthase
NDR85_RS15310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NDR85_RS15315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NDR85_RS15325	COG1506	peptidase
NDR85_RS15330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NDR85_RS15335	COG1116	anion transmembrane transporter activity
NDR85_RS15340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NDR85_RS15345	COG0494	nUDIX hydrolase
NDR85_RS15350	COG4824	toxin secretion phage lysis holin
NDR85_RS15355	COG0783	Belongs to the Dps family
NDR85_RS15370	COG1854	S-ribosylhomocysteine lyase activity
NDR85_RS15375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NDR85_RS15380	COG0288	reversible hydration of carbon dioxide
NDR85_RS15385	COG0254	rRNA binding
NDR85_RS15390	COG1271	oxidase subunit
NDR85_RS15395	COG1294	oxidase, subunit
NDR85_RS15405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NDR85_RS15410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NDR85_RS15410	COG1321	iron dependent repressor
NDR85_RS15415	COG1121	(ABC) transporter
NDR85_RS15420	COG0803	Belongs to the bacterial solute-binding protein 9 family
NDR85_RS15425	COG4948	Mandelate Racemase Muconate Lactonizing
NDR85_RS15430	COG0318	PFAM AMP-dependent synthetase and ligase
NDR85_RS15435	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NDR85_RS15440	COG0596	Alpha beta hydrolase
NDR85_RS15445	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NDR85_RS15450	COG1169	isochorismate synthase
NDR85_RS15455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NDR85_RS15460	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NDR85_RS15465	COG0058	SHG alpha-glucan phosphorylase activity
NDR85_RS15470	COG0297	glycogen (starch) synthase activity
NDR85_RS15475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NDR85_RS15480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NDR85_RS15485	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NDR85_RS15610	COG3859	Proton-coupled thiamine transporter YuaJ
NDR85_RS15615	COG1247	-acetyltransferase
NDR85_RS15620	COG2268	Band 7 protein
NDR85_RS15625	COG1585	Membrane protein implicated in regulation of membrane protease activity
NDR85_RS15630	COG2318	DinB family
NDR85_RS15640	COG1454	alcohol dehydrogenase
NDR85_RS15645	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS15650	COG1510	regulation of RNA biosynthetic process
NDR85_RS15660	COG0569	domain protein
NDR85_RS15665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NDR85_RS15670	COG4682	membrane
NDR85_RS15675	COG1705	Flagellar rod assembly protein muramidase FlgJ
NDR85_RS15680	COG0477	Major facilitator Superfamily
NDR85_RS15685	COG5553	Cysteine dioxygenase type I
NDR85_RS15695	COG1968	undecaprenyl-diphosphatase activity
NDR85_RS15700	COG0628	permease
NDR85_RS15705	COG0673	inositol 2-dehydrogenase activity
NDR85_RS15710	COG4806	L-rhamnose isomerase
NDR85_RS15715	COG3254	rhamnose metabolic process
NDR85_RS15720	COG1070	Carbohydrate kinase
NDR85_RS15725	COG1349	DNA-binding transcription factor activity
NDR85_RS15730	COG3347	Dehydrogenase
NDR85_RS15730	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS15735	COG0840	transmembrane signaling receptor activity
NDR85_RS15740	COG0840	transmembrane signaling receptor activity
NDR85_RS15745	COG0840	transmembrane signaling receptor activity
NDR85_RS15750	COG0840	transmembrane signaling receptor activity
NDR85_RS15765	COG2070	2-Nitropropane dioxygenase
NDR85_RS15770	COG0432	Pfam Uncharacterised protein family UPF0047
NDR85_RS15775	COG0366	Alpha amylase catalytic
NDR85_RS15780	COG1253	flavin adenine dinucleotide binding
NDR85_RS15785	COG2738	Putative neutral zinc metallopeptidase
NDR85_RS15800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NDR85_RS15815	COG0166	Belongs to the GPI family
NDR85_RS15820	COG1979	alcohol dehydrogenase
NDR85_RS15825	COG1979	alcohol dehydrogenase
NDR85_RS15830	COG2155	Conserved Protein
NDR85_RS15835	COG1098	S1 RNA binding domain
NDR85_RS15840	COG0436	Aminotransferase
NDR85_RS15845	COG1522	sequence-specific DNA binding
NDR85_RS15850	COG2267	carboxylic ester hydrolase activity
NDR85_RS15860	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NDR85_RS15865	COG2205	protein histidine kinase activity
NDR85_RS15875	COG5018	Exonuclease
NDR85_RS15885	COG2814	Major facilitator Superfamily
NDR85_RS15890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDR85_RS15895	COG3011	Protein conserved in bacteria
NDR85_RS15905	COG3290	protein histidine kinase activity
NDR85_RS15910	COG4565	transcriptional regulatory protein
NDR85_RS15915	COG1744	ABC transporter substrate-binding protein PnrA-like
NDR85_RS15920	COG3845	ABC transporter
NDR85_RS15925	COG4603	Belongs to the binding-protein-dependent transport system permease family
NDR85_RS15930	COG1079	Belongs to the binding-protein-dependent transport system permease family
NDR85_RS15935	COG3493	citrate carrier protein
NDR85_RS15945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NDR85_RS15945	COG2111	Na H antiporter
NDR85_RS15950	COG2111	Na H antiporter
NDR85_RS15955	COG1006	Multisubunit Na H antiporter MnhC subunit
NDR85_RS15960	COG0651	ATP synthesis coupled electron transport
NDR85_RS15965	COG1863	multisubunit Na H antiporter MnhE subunit
NDR85_RS15970	COG2212	antiporter activity
NDR85_RS15975	COG1320	monovalent cation:proton antiporter activity
NDR85_RS15980	COG2050	protein possibly involved in aromatic compounds catabolism
NDR85_RS15985	COG2197	response regulator
NDR85_RS15990	COG4585	Histidine kinase
NDR85_RS16000	COG0142	geranyltranstransferase activity
NDR85_RS16015	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NDR85_RS16020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NDR85_RS16025	COG1335	isochorismatase
NDR85_RS16030	COG5506	Protein of unknown function (DUF1694)
NDR85_RS16045	COG0628	permease
NDR85_RS16055	COG1418	mRNA catabolic process
NDR85_RS16060	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS16070	COG1511	domain protein
NDR85_RS16075	COG1674	ftsk spoiiie
NDR85_RS16075	COG0433	COG0433 Predicted ATPase
NDR85_RS16080	COG4499	WXG100 protein secretion system (Wss), protein YukC
NDR85_RS16085	COG5417	Belongs to the EsaB family
NDR85_RS16090	COG4842	Belongs to the WXG100 family
NDR85_RS16095	COG2508	Transcriptional regulator
NDR85_RS16095	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NDR85_RS16100	COG0686	Belongs to the AlaDH PNT family
NDR85_RS16105	COG5634	Uncharacterized conserved protein (DUF2278)
NDR85_RS16110	COG3251	PFAM MbtH domain protein
NDR85_RS16115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS16120	COG1535	isochorismatase
NDR85_RS16120	COG3433	isochorismatase activity
NDR85_RS16125	COG1021	2,3-dihydroxybenzoate-AMP ligase
NDR85_RS16130	COG1169	isochorismate synthase
NDR85_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS16140	COG2819	hydrolase of the alpha beta superfamily
NDR85_RS16145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NDR85_RS16150	COG1268	BioY protein
NDR85_RS16155	COG2056	Na+-H+ antiporter family
NDR85_RS16160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NDR85_RS16165	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NDR85_RS16170	COG3584	3D domain protein
NDR85_RS16185	COG1252	NADH dehydrogenase
NDR85_RS16190	COG0492	ferredoxin-NADP+ reductase activity
NDR85_RS16200	COG0516	GMP reductase activity
NDR85_RS16205	COG0316	Belongs to the HesB IscA family
NDR85_RS16210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NDR85_RS16215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDR85_RS16220	COG4844	belongs to the
NDR85_RS16225	COG1252	NADH dehydrogenase
NDR85_RS16230	COG4837	Protein of unknown function (DUF1462)
NDR85_RS16235	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NDR85_RS16240	COG1506	peptidase
NDR85_RS16240	COG4946	Tricorn protease homolog
NDR85_RS16240	COG0823	Involved in the tonB-independent uptake of proteins
NDR85_RS16245	COG0083	homoserine kinase activity
NDR85_RS16250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NDR85_RS16255	COG0460	homoserine dehydrogenase
NDR85_RS16260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NDR85_RS16265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NDR85_RS16270	COG0647	UMP catabolic process
NDR85_RS16275	COG2445	Protein of unknown function DUF86
NDR85_RS16280	COG4470	Protein conserved in bacteria
NDR85_RS16295	COG0739	heme binding
NDR85_RS16305	COG3377	Domain of unknown function (DUF1805)
NDR85_RS16310	COG0737	Belongs to the 5'-nucleotidase family
NDR85_RS16315	COG0730	response to heat
NDR85_RS16320	COG1801	Protein of unknown function DUF72
NDR85_RS16330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NDR85_RS16335	COG2508	Transcriptional regulator
NDR85_RS16340	COG2233	PERMEase
NDR85_RS16345	COG2233	PERMEase
NDR85_RS16350	COG3195	allantoin biosynthetic process
NDR85_RS16350	COG3648	Uricase
NDR85_RS16355	COG2351	hydroxyisourate hydrolase activity
NDR85_RS16370	COG2080	2 iron, 2 sulfur cluster binding
NDR85_RS16375	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NDR85_RS16380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NDR85_RS16385	COG2068	MobA-Related Protein
NDR85_RS16390	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NDR85_RS16395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NDR85_RS16400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NDR85_RS16405	COG2356	endonuclease I
NDR85_RS16410	COG3842	ATPase activity
NDR85_RS16415	COG2188	Transcriptional regulator
NDR85_RS16420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDR85_RS16425	COG0395	ABC-type sugar transport system, permease component
NDR85_RS16430	COG1175	transmembrane transport
NDR85_RS16435	COG1653	transport
NDR85_RS16440	COG2222	sugar isomerase
NDR85_RS16445	COG0322	excinuclease ABC activity
NDR85_RS16450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NDR85_RS16465	COG0719	Fe-S assembly protein
NDR85_RS16470	COG0822	iron-sulfur transferase activity
NDR85_RS16475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NDR85_RS16480	COG0719	Fe-S assembly protein
NDR85_RS16485	COG0396	ATPase activity
NDR85_RS16495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NDR85_RS16500	COG1464	Belongs to the NlpA lipoprotein family
NDR85_RS16505	COG2011	ABC-type metal ion transport system permease component
NDR85_RS16510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NDR85_RS16520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NDR85_RS16525	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NDR85_RS16535	COG0509	glycine decarboxylation via glycine cleavage system
NDR85_RS16540	COG1393	Belongs to the ArsC family
NDR85_RS16545	COG1960	acyl-CoA dehydrogenase activity
NDR85_RS16550	COG0183	Belongs to the thiolase family
NDR85_RS16555	COG1250	3-hydroxyacyl-CoA dehydrogenase
NDR85_RS16555	COG1024	Enoyl-CoA hydratase
NDR85_RS16565	COG0506	proline dehydrogenase activity
NDR85_RS16575	COG5577	PFAM Coat F domain
NDR85_RS16580	COG1846	Transcriptional regulator
NDR85_RS16585	COG0477	Major facilitator Superfamily
NDR85_RS16590	COG1942	4-Oxalocrotonate Tautomerase
NDR85_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS16600	COG0583	DNA-binding transcription factor activity
NDR85_RS16610	COG1120	ATPase activity
NDR85_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS16630	COG0783	Belongs to the Dps family
NDR85_RS16635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDR85_RS16640	COG0745	RESPONSE REGULATOR receiver
NDR85_RS16645	COG2205	protein histidine kinase activity
NDR85_RS16645	COG2770	Histidine kinase
NDR85_RS16655	COG1309	transcriptional regulator
NDR85_RS16660	COG0114	fumarate hydratase activity
NDR85_RS16670	COG0697	spore germination
NDR85_RS16675	COG0814	amino acid
NDR85_RS16685	COG2197	response regulator
NDR85_RS16690	COG4585	Histidine kinase
NDR85_RS16695	COG4758	membrane
NDR85_RS16700	COG3595	metallopeptidase activity
NDR85_RS16705	COG1842	Phage shock protein A
NDR85_RS16710	COG4758	membrane
NDR85_RS16715	COG2814	Major facilitator Superfamily
NDR85_RS16720	COG2096	Adenosyltransferase
NDR85_RS16725	COG1120	ATPase activity
NDR85_RS16730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS16735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NDR85_RS16740	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS16745	COG3386	PFAM SMP-30 Gluconolaconase
NDR85_RS16750	COG2205	protein histidine kinase activity
NDR85_RS16755	COG0745	RESPONSE REGULATOR receiver
NDR85_RS16765	COG1191	sigma factor activity
NDR85_RS16775	COG2140	Oxalate decarboxylase
NDR85_RS16785	COG0577	efflux transmembrane transporter activity
NDR85_RS16790	COG1136	(ABC) transporter
NDR85_RS16795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NDR85_RS16800	COG1120	ATPase activity
NDR85_RS16805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS16810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NDR85_RS16815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NDR85_RS16820	COG0531	amino acid
NDR85_RS16830	COG1988	membrane-bound metal-dependent
NDR85_RS16835	COG1368	sulfuric ester hydrolase activity
NDR85_RS16840	COG1910	domain protein
NDR85_RS16845	COG0725	ABC transporter, periplasmic molybdate-binding protein
NDR85_RS16850	COG4149	molybdate abc transporter
NDR85_RS16855	COG0656	L-ascorbic acid biosynthetic process
NDR85_RS16870	COG0025	NhaP-type Na H and K H
NDR85_RS16875	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NDR85_RS16880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NDR85_RS16885	COG3973	AAA domain
NDR85_RS16895	COG2860	membrane
NDR85_RS16900	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NDR85_RS16905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NDR85_RS16910	COG2217	Heavy metal translocating P-type atpase
NDR85_RS16915	COG2217	Heavy metal translocating P-type atpase
NDR85_RS16920	COG2608	mercury ion transmembrane transporter activity
NDR85_RS16925	COG1937	Protein conserved in bacteria
NDR85_RS16930	COG0673	inositol 2-dehydrogenase activity
NDR85_RS16935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NDR85_RS16940	COG1289	transmembrane transporter activity
NDR85_RS16945	COG1802	Transcriptional regulator
NDR85_RS16950	COG0697	spore germination
NDR85_RS16960	COG2076	Multidrug Resistance protein
NDR85_RS16965	COG1309	transcriptional regulator
NDR85_RS16970	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS16985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NDR85_RS16990	COG0557	exoribonuclease II activity
NDR85_RS16995	COG1647	Serine aminopeptidase, S33
NDR85_RS17000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NDR85_RS17005	COG0596	Alpha beta hydrolase
NDR85_RS17010	COG1476	TRANSCRIPTIONal
NDR85_RS17015	COG1396	sequence-specific DNA binding
NDR85_RS17020	COG1396	sequence-specific DNA binding
NDR85_RS17025	COG1733	regulation of RNA biosynthetic process
NDR85_RS17030	COG0840	transmembrane signaling receptor activity
NDR85_RS17035	COG1174	glycine betaine transport
NDR85_RS17040	COG1732	Glycine betaine
NDR85_RS17045	COG1174	glycine betaine transport
NDR85_RS17050	COG0517	IMP dehydrogenase activity
NDR85_RS17050	COG1125	glycine betaine transport
NDR85_RS17055	COG1510	regulation of RNA biosynthetic process
NDR85_RS17060	COG1174	glycine betaine transport
NDR85_RS17065	COG1732	Glycine betaine
NDR85_RS17070	COG1174	glycine betaine transport
NDR85_RS17075	COG1125	glycine betaine transport
NDR85_RS17075	COG0517	IMP dehydrogenase activity
NDR85_RS17080	COG1510	regulation of RNA biosynthetic process
NDR85_RS17090	COG3064	Membrane
NDR85_RS17095	COG4640	response to antibiotic
NDR85_RS17100	COG0456	acetyltransferase
NDR85_RS17115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NDR85_RS17135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NDR85_RS17140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NDR85_RS17150	COG2234	aminopeptidase activity
NDR85_RS17160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NDR85_RS17165	COG0149	triose-phosphate isomerase activity
NDR85_RS17170	COG0126	phosphoglycerate kinase activity
NDR85_RS17180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NDR85_RS17185	COG2390	Transcriptional regulator
NDR85_RS17190	COG2814	Major facilitator Superfamily
NDR85_RS17195	COG1609	Transcriptional regulator
NDR85_RS17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDR85_RS17205	COG0583	DNA-binding transcription factor activity
NDR85_RS17210	COG0697	spore germination
NDR85_RS17215	COG1113	amino acid transport
NDR85_RS17220	COG3858	chitin binding
NDR85_RS17225	COG1556	Lactate utilization protein
NDR85_RS17230	COG1139	Iron-sulfur cluster binding protein
NDR85_RS17235	COG0247	lactate metabolic process
NDR85_RS17245	COG0596	Alpha beta hydrolase
NDR85_RS17250	COG2208	phosphoserine phosphatase activity
NDR85_RS17255	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NDR85_RS17260	COG1874	Beta-galactosidase
NDR85_RS17265	COG3833	ABC-type maltose transport systems, permease component
NDR85_RS17270	COG1175	transmembrane transport
NDR85_RS17275	COG2182	Extracellular solute-binding protein
NDR85_RS17280	COG1609	Transcriptional regulator
NDR85_RS17285	COG2186	Transcriptional regulator
NDR85_RS17290	COG1620	l-lactate permease
NDR85_RS17295	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NDR85_RS17305	COG5039	Polysaccharide pyruvyl transferase
NDR85_RS17310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NDR85_RS17315	COG0110	maltose O-acetyltransferase activity
NDR85_RS17320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NDR85_RS17325	COG2244	polysaccharide biosynthetic process
NDR85_RS17330	COG1216	Glycosyl transferase, family 2
NDR85_RS17335	COG5039	Polysaccharide pyruvyl transferase
NDR85_RS17340	COG1216	Glycosyl transferase, family 2
NDR85_RS17350	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS17355	COG1215	transferase activity, transferring glycosyl groups
NDR85_RS17360	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS17365	COG1086	Polysaccharide biosynthesis protein
NDR85_RS17370	COG0489	protein tyrosine kinase activity
NDR85_RS17380	COG1396	sequence-specific DNA binding
NDR85_RS17385	COG2272	Belongs to the type-B carboxylesterase lipase family
NDR85_RS17395	COG3479	Phenolic acid decarboxylase
NDR85_RS17405	COG1794	racemase activity, acting on amino acids and derivatives
NDR85_RS17410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NDR85_RS17420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDR85_RS17425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NDR85_RS17430	COG0640	Transcriptional regulator
NDR85_RS17435	COG1621	beta-fructofuranosidase activity
NDR85_RS17440	COG1621	beta-fructofuranosidase activity
NDR85_RS17445	COG0531	amino acid
NDR85_RS17450	COG1309	transcriptional regulator
NDR85_RS17455	COG2076	Multidrug Resistance protein
NDR85_RS17460	COG2076	Multidrug Resistance protein
NDR85_RS17480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NDR85_RS17485	COG0366	Alpha amylase catalytic
NDR85_RS17490	COG1554	hydrolase, family 65, central catalytic
NDR85_RS17495	COG5521	maltodextrose utilization protein MalA
NDR85_RS17500	COG3833	ABC-type maltose transport systems, permease component
NDR85_RS17505	COG1175	transmembrane transport
NDR85_RS17510	COG2182	Extracellular solute-binding protein
NDR85_RS17520	COG1609	Transcriptional regulator
NDR85_RS17525	COG1611	Belongs to the LOG family
NDR85_RS17530	COG1694	Mazg nucleotide pyrophosphohydrolase
NDR85_RS17535	COG0659	secondary active sulfate transmembrane transporter activity
NDR85_RS17540	COG0288	reversible hydration of carbon dioxide
NDR85_RS17545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NDR85_RS17550	COG0577	efflux transmembrane transporter activity
NDR85_RS17555	COG1136	(ABC) transporter
NDR85_RS17560	COG5002	protein histidine kinase activity
NDR85_RS17565	COG0745	RESPONSE REGULATOR receiver
NDR85_RS17575	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NDR85_RS17580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS17585	COG1481	regulation of sporulation
NDR85_RS17590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NDR85_RS17595	COG1660	Displays ATPase and GTPase activities
NDR85_RS17600	COG1051	belongs to the nudix hydrolase family
NDR85_RS17605	COG0492	ferredoxin-NADP+ reductase activity
NDR85_RS17610	COG3883	PFAM NLP P60 protein
NDR85_RS17610	COG0791	NLP P60 protein
NDR85_RS17615	COG0457	Tetratricopeptide repeat
NDR85_RS17620	COG1132	(ABC) transporter
NDR85_RS17650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NDR85_RS17650	COG0140	phosphoribosyl-ATP diphosphatase activity
NDR85_RS17655	COG0107	imidazoleglycerol-phosphate synthase activity
NDR85_RS17660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NDR85_RS17665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NDR85_RS17670	COG0131	Imidazoleglycerol-phosphate dehydratase
NDR85_RS17675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NDR85_RS17680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NDR85_RS17685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NDR85_RS17690	COG4990	cell redox homeostasis
NDR85_RS17695	COG5297	Belongs to the glycosyl hydrolase family 6
NDR85_RS17700	COG0110	maltose O-acetyltransferase activity
NDR85_RS17705	COG0546	phosphoglycolate phosphatase activity
NDR85_RS17710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NDR85_RS17715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NDR85_RS17720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NDR85_RS17725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NDR85_RS17730	COG0363	glucosamine-6-phosphate deaminase activity
NDR85_RS17735	COG2188	Transcriptional regulator
NDR85_RS17740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NDR85_RS17745	COG1846	Transcriptional regulator
NDR85_RS17750	COG2814	Major facilitator Superfamily
NDR85_RS17755	COG1950	PFAM Membrane protein of
NDR85_RS17760	COG1983	PspC domain protein
NDR85_RS17765	COG3595	metallopeptidase activity
NDR85_RS17780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NDR85_RS17790	COG4897	Protein conserved in bacteria
NDR85_RS17795	COG0574	Belongs to the PEP-utilizing enzyme family
NDR85_RS17795	COG3848	Pyruvate phosphate dikinase
NDR85_RS17800	COG1309	transcriptional regulator
NDR85_RS17805	COG2814	Major facilitator Superfamily
NDR85_RS17810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDR85_RS17820	COG0793	Belongs to the peptidase S41A family
NDR85_RS17820	COG3409	Peptidoglycan-binding domain 1 protein
NDR85_RS17825	COG2177	Part of the ABC transporter FtsEX involved in
NDR85_RS17830	COG2884	Cell division ATP-binding protein ftsE
NDR85_RS17835	COG2010	Cytochrome c
NDR85_RS17840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS17850	COG0653	protein targeting
NDR85_RS17855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NDR85_RS17870	COG1516	flagellar protein fliS
NDR85_RS17875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NDR85_RS17880	COG1334	flagellar protein FlaG
NDR85_RS17885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NDR85_RS17890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NDR85_RS17895	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NDR85_RS17905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NDR85_RS17910	COG4786	Flagellar basal body rod
NDR85_RS17910	COG1256	bacterial-type flagellum assembly
NDR85_RS17915	COG3418	PFAM FlgN family protein
NDR85_RS17920	COG2747	anti-sigma28 factor FlgM
NDR85_RS17930	COG1040	competence protein
NDR85_RS17940	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NDR85_RS17945	COG1307	EDD domain protein, DegV family
NDR85_RS17950	COG2197	response regulator
NDR85_RS17955	COG4585	Histidine kinase
NDR85_RS17960	COG1739	Uncharacterized protein family UPF0029
NDR85_RS17965	COG1316	TRANSCRIPTIONal
NDR85_RS17970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NDR85_RS17975	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS17980	COG1215	transferase activity, transferring glycosyl groups
NDR85_RS17985	COG3206	protein involved in exopolysaccharide biosynthesis
NDR85_RS17990	COG3307	-O-antigen
NDR85_RS17995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDR85_RS18000	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS18000	COG0297	glycogen (starch) synthase activity
NDR85_RS18005	COG2244	polysaccharide biosynthetic process
NDR85_RS18015	COG2247	cell wall binding repeat
NDR85_RS18015	COG0860	N-Acetylmuramoyl-L-alanine amidase
NDR85_RS18020	COG2247	cell wall binding repeat
NDR85_RS18020	COG2385	sporulation resulting in formation of a cellular spore
NDR85_RS18030	COG1316	TRANSCRIPTIONal
NDR85_RS18035	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NDR85_RS18040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NDR85_RS18055	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS18060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NDR85_RS18085	COG1134	teichoic acid transport
NDR85_RS18090	COG1682	transport, permease protein
NDR85_RS18095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NDR85_RS18100	COG0438	transferase activity, transferring glycosyl groups
NDR85_RS18105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NDR85_RS18110	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NDR85_RS18115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NDR85_RS18125	COG4193	domain, Protein
NDR85_RS18130	COG1482	cell wall glycoprotein biosynthetic process
NDR85_RS18135	COG0697	spore germination
NDR85_RS18140	COG0814	amino acid
NDR85_RS18150	COG2814	Major facilitator Superfamily
NDR85_RS18155	COG1316	TRANSCRIPTIONal
NDR85_RS18160	COG0561	phosphatase activity
NDR85_RS18165	COG0791	NLP P60 protein
NDR85_RS18175	COG2843	Capsule synthesis protein
NDR85_RS18185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NDR85_RS18190	COG1609	Transcriptional regulator
NDR85_RS18195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDR85_RS18200	COG1869	D-ribose catabolic process
NDR85_RS18205	COG1129	ABC transporter
NDR85_RS18210	COG1172	Belongs to the binding-protein-dependent transport system permease family
NDR85_RS18215	COG1879	ABC-type sugar transport system periplasmic component
NDR85_RS18220	COG3103	Sh3 type 3 domain protein
NDR85_RS18230	COG2249	NAD(P)H dehydrogenase (quinone) activity
NDR85_RS18235	COG3527	Alpha-acetolactate decarboxylase
NDR85_RS18240	COG0028	Belongs to the TPP enzyme family
NDR85_RS18245	COG0583	DNA-binding transcription factor activity
NDR85_RS18250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NDR85_RS18265	COG5337	Spore coat protein CotH
NDR85_RS18275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDR85_RS18280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS18295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NDR85_RS18305	COG0405	Gamma-glutamyltransferase
NDR85_RS18310	COG1522	sequence-specific DNA binding
NDR85_RS18315	COG2059	Chromate
NDR85_RS18320	COG2059	Chromate
NDR85_RS18330	COG0655	NAD(P)H dehydrogenase (quinone) activity
NDR85_RS18335	COG0583	DNA-binding transcription factor activity
NDR85_RS18350	COG5444	nuclease activity
NDR85_RS18370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NDR85_RS18375	COG4464	protein tyrosine phosphatase activity
NDR85_RS18380	COG0489	protein tyrosine kinase activity
NDR85_RS18385	COG3944	biosynthesis protein
NDR85_RS18395	COG4715	Zinc finger, swim domain protein
NDR85_RS18400	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NDR85_RS18405	COG0561	phosphatase activity
NDR85_RS18410	COG1349	DNA-binding transcription factor activity
NDR85_RS18415	COG0629	single-stranded DNA binding
NDR85_RS18430	COG2602	Beta-lactamase
NDR85_RS18435	COG1970	mechanosensitive ion channel activity
NDR85_RS18440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NDR85_RS18445	COG0457	Tetratricopeptide repeat
NDR85_RS18450	COG4786	Flagellar basal body rod
NDR85_RS18455	COG4786	Flagellar basal body rod
NDR85_RS18460	COG1077	Cell shape determining protein MreB Mrl
NDR85_RS18465	COG1609	Transcriptional regulator
NDR85_RS18475	COG1846	Transcriptional regulator
NDR85_RS18480	COG2814	Major facilitator Superfamily
NDR85_RS18485	COG3420	alginic acid biosynthetic process
NDR85_RS18490	COG1953	Uracil, thiamine, allantoin
NDR85_RS18495	COG0477	Major facilitator Superfamily
NDR85_RS18500	COG1335	isochorismatase
NDR85_RS18510	COG0004	ammonium transporteR
NDR85_RS18515	COG0347	Belongs to the P(II) protein family
NDR85_RS18520	COG0671	phosphoesterase, PA-phosphatase related
NDR85_RS18530	COG0739	heme binding
NDR85_RS18535	COG1247	-acetyltransferase
NDR85_RS18550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDR85_RS18560	COG2910	NAD(P)H-binding
NDR85_RS18565	COG1959	2 iron, 2 sulfur cluster binding
NDR85_RS18570	COG0804	urea catabolic process
NDR85_RS18575	COG0832	Belongs to the urease beta subunit family
NDR85_RS18580	COG0831	urea catabolic process
NDR85_RS18610	COG3237	CsbD-like
NDR85_RS18615	COG1994	Peptidase M50
NDR85_RS18620	COG0457	Tetratricopeptide repeat
NDR85_RS18625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NDR85_RS18630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NDR85_RS18640	COG2304	oxidoreductase activity
NDR85_RS18645	COG2304	oxidoreductase activity
NDR85_RS18650	COG2385	sporulation resulting in formation of a cellular spore
NDR85_RS18655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDR85_RS18665	COG4836	Membrane
NDR85_RS18675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NDR85_RS18680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NDR85_RS18685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NDR85_RS18695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NDR85_RS18700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NDR85_RS18710	COG0356	it plays a direct role in the translocation of protons across the membrane
NDR85_RS18720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NDR85_RS18725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NDR85_RS18730	COG4475	Protein of unknown function (DUF436)
NDR85_RS18735	COG0698	ribose 5-phosphate isomerase
NDR85_RS18740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NDR85_RS18745	COG1971	Probably functions as a manganese efflux pump
NDR85_RS18750	COG0009	L-threonylcarbamoyladenylate synthase
NDR85_RS18755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NDR85_RS18775	COG2890	protein-(glutamine-N5) methyltransferase activity
NDR85_RS18780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NDR85_RS18785	COG0346	lactoylglutathione lyase activity
NDR85_RS18790	COG0789	Transcriptional regulator
NDR85_RS18795	COG0679	Auxin Efflux Carrier
NDR85_RS18800	COG0281	malic enzyme
NDR85_RS18805	COG1435	thymidine kinase activity
NDR85_RS18815	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NDR85_RS18825	COG1494	fructose-1,6-bisphosphatase
NDR85_RS18830	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NDR85_RS18835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NDR85_RS18840	COG0191	fructose-bisphosphate aldolase activity
NDR85_RS18845	COG2204	response regulator
NDR85_RS18850	COG4821	SIS domain
NDR85_RS18855	COG0504	CTP synthase activity
NDR85_RS18860	COG3343	RNA polymerase activity
NDR85_RS18865	COG1960	acyl-CoA dehydrogenase activity
NDR85_RS18870	COG2181	nitrate reductase activity
NDR85_RS18870	COG0247	lactate metabolic process
NDR85_RS18875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDR85_RS18880	COG4294	response to UV
NDR85_RS18890	COG1476	TRANSCRIPTIONal
NDR85_RS18900	COG1132	(ABC) transporter
NDR85_RS18905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NDR85_RS18915	COG2181	nitrate reductase activity
NDR85_RS18920	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NDR85_RS18925	COG1140	nitrate reductase beta subunit
NDR85_RS18930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NDR85_RS18935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDR85_RS18945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NDR85_RS18950	COG2223	nitrite transmembrane transporter activity
NDR85_RS18955	COG0018	arginyl-trna synthetase
NDR85_RS18960	COG4506	Protein conserved in bacteria
NDR85_RS18975	COG0535	radical SAM domain protein
NDR85_RS18985	COG1131	(ABC) transporter
NDR85_RS18995	COG0612	Peptidase, M16
NDR85_RS19015	COG3391	amine dehydrogenase activity
NDR85_RS19020	COG0457	Tetratricopeptide repeat
NDR85_RS19030	COG0010	Belongs to the arginase family
NDR85_RS19035	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NDR85_RS19040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NDR85_RS19055	COG1994	Peptidase M50
NDR85_RS19060	COG1942	4-Oxalocrotonate Tautomerase
NDR85_RS19065	COG1846	Transcriptional regulator
NDR85_RS19070	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NDR85_RS19080	COG0477	Major facilitator Superfamily
NDR85_RS19085	COG1959	2 iron, 2 sulfur cluster binding
NDR85_RS19090	COG3465	dGTPase activity
NDR85_RS19095	COG1078	dGTPase activity
NDR85_RS19100	COG4844	belongs to the
NDR85_RS19110	COG0697	spore germination
NDR85_RS19115	COG0095	Lipoate-protein ligase
NDR85_RS19120	COG0583	DNA-binding transcription factor activity
NDR85_RS19125	COG0280	phosphate acetyltransferase
NDR85_RS19130	COG3253	May function as heme-dependent peroxidase
NDR85_RS19135	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS19140	COG0436	Aminotransferase
NDR85_RS19145	COG2814	Major facilitator Superfamily
NDR85_RS19150	COG0151	Belongs to the GarS family
NDR85_RS19155	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS19160	COG1917	Cupin 2, conserved barrel domain protein
NDR85_RS19165	COG0077	Prephenate dehydratase
NDR85_RS19170	COG2814	Major facilitator Superfamily
NDR85_RS19175	COG2814	Major facilitator Superfamily
NDR85_RS19180	COG0833	amino acid
NDR85_RS19185	COG4187	Peptidase family M20/M25/M40
NDR85_RS19190	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS19195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NDR85_RS19205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NDR85_RS19210	COG1091	dTDP-4-dehydrorhamnose reductase activity
NDR85_RS19215	COG1088	dTDP-glucose 4,6-dehydratase activity
NDR85_RS19220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NDR85_RS19225	COG3980	spore coat polysaccharide biosynthesis protein
NDR85_RS19230	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NDR85_RS19235	COG2089	acid synthase
NDR85_RS19240	COG0456	acetyltransferase
NDR85_RS19245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NDR85_RS19250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NDR85_RS19255	COG0463	Glycosyl transferase, family 2
NDR85_RS19265	COG2363	Small membrane protein
NDR85_RS19270	COG2233	PERMEase
NDR85_RS19280	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS19285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NDR85_RS19290	COG1216	Glycosyl transferase, family 2
NDR85_RS19305	COG1695	Transcriptional regulator
NDR85_RS19310	COG0351	phosphomethylpyrimidine kinase
NDR85_RS19320	COG1621	beta-fructofuranosidase activity
NDR85_RS19325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS19325	COG1263	PTS System
NDR85_RS19330	COG2116	formate transmembrane transporter activity
NDR85_RS19335	COG3711	transcriptional antiterminator
NDR85_RS19345	COG1404	Belongs to the peptidase S8 family
NDR85_RS19350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDR85_RS19355	COG0778	Nitroreductase
NDR85_RS19360	COG0772	Belongs to the SEDS family
NDR85_RS19385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NDR85_RS19390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NDR85_RS19395	COG2261	transglycosylase associated protein
NDR85_RS19400	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NDR85_RS19405	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NDR85_RS19410	COG2246	polysaccharide biosynthetic process
NDR85_RS19415	COG1309	transcriptional regulator
NDR85_RS19425	COG3162	membrane
NDR85_RS19430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NDR85_RS19435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NDR85_RS19440	COG2837	iron assimilation
NDR85_RS19445	COG2822	iron ion transport
NDR85_RS19450	COG0672	)-iron permease
NDR85_RS19455	COG0352	thiamine-phosphate diphosphorylase activity
NDR85_RS19460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NDR85_RS19465	COG0583	DNA-binding transcription factor activity
NDR85_RS19470	COG1380	Effector of murein hydrolase LrgA
NDR85_RS19475	COG1346	cytolysis
NDR85_RS19480	COG2814	Major facilitator Superfamily
NDR85_RS19485	COG4895	conserved protein (DUF2196)
NDR85_RS19490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NDR85_RS19495	COG0346	lactoylglutathione lyase activity
NDR85_RS19505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NDR85_RS19510	COG1404	Belongs to the peptidase S8 family
NDR85_RS19515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS19515	COG1263	PTS System
NDR85_RS19520	COG3711	transcriptional antiterminator
NDR85_RS19525	COG1442	glycosyl transferase family 8
NDR85_RS19530	COG5522	Integral membrane protein (intg_mem_TP0381)
NDR85_RS19535	COG1846	Transcriptional regulator
NDR85_RS19540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NDR85_RS19545	COG2234	aminopeptidase activity
NDR85_RS19560	COG2814	Major facilitator Superfamily
NDR85_RS19565	COG2357	RelA SpoT domain protein
NDR85_RS19570	COG1575	Belongs to the MenA family. Type 1 subfamily
NDR85_RS19580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NDR85_RS19585	COG1696	Membrane protein involved in D-alanine export
NDR85_RS19590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NDR85_RS19595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NDR85_RS19600	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NDR85_RS19605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NDR85_RS19610	COG1486	melibiose metabolic process
NDR85_RS19615	COG1447	Phosphotransferase system cellobiose-specific component IIA
NDR85_RS19620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NDR85_RS19625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NDR85_RS19630	COG3711	transcriptional antiterminator
NDR85_RS19630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NDR85_RS19640	COG2094	Belongs to the DNA glycosylase MPG family
NDR85_RS19645	COG0753	catalase activity
NDR85_RS19650	COG2814	Major facilitator Superfamily
NDR85_RS19655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NDR85_RS19660	COG1131	(ABC) transporter
NDR85_RS19680	COG1595	DNA-templated transcription, initiation
NDR85_RS19685	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NDR85_RS19695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NDR85_RS19700	COG4988	ABC transporter
NDR85_RS19705	COG1294	oxidase, subunit
NDR85_RS19710	COG1271	oxidase subunit
NDR85_RS19715	COG3493	citrate carrier protein
NDR85_RS19720	COG0501	Belongs to the peptidase M48B family
NDR85_RS19730	COG0726	polysaccharide deacetylase
NDR85_RS19740	COG3842	ATPase activity
NDR85_RS19745	COG2508	Transcriptional regulator
NDR85_RS19750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NDR85_RS19760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NDR85_RS19765	COG1881	PFAM PEBP family protein
NDR85_RS19770	COG0583	DNA-binding transcription factor activity
NDR85_RS19785	COG2195	Cleaves the N-terminal amino acid of tripeptides
NDR85_RS19800	COG4894	glucomannan catabolic process
NDR85_RS19805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NDR85_RS19810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NDR85_RS19815	COG3290	protein histidine kinase activity
NDR85_RS19815	COG3829	transcription factor binding
NDR85_RS19820	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS19825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NDR85_RS19830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NDR85_RS19835	COG2610	gluconate transmembrane transporter activity
NDR85_RS19840	COG0500	methyltransferase
NDR85_RS19845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDR85_RS19860	COG0753	catalase activity
NDR85_RS19860	COG0693	protein deglycase activity
NDR85_RS19865	COG2851	Citrate transporter
NDR85_RS19875	COG2723	6-phospho-beta-galactosidase activity
NDR85_RS19880	COG2190	(PTS) system
NDR85_RS19880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS19880	COG1263	PTS System
NDR85_RS19885	COG3711	transcriptional antiterminator
NDR85_RS19895	COG2270	Major facilitator Superfamily
NDR85_RS19900	COG0513	Belongs to the DEAD box helicase family
NDR85_RS19905	COG3401	FG-GAP repeat protein
NDR85_RS19905	COG2755	lipolytic protein G-D-S-L family
NDR85_RS19985	COG0697	spore germination
NDR85_RS19990	COG0589	response to stress
NDR85_RS19995	COG2723	6-phospho-beta-galactosidase activity
NDR85_RS20000	COG1263	PTS System
NDR85_RS20000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NDR85_RS20000	COG2190	(PTS) system
NDR85_RS20015	COG5444	nuclease activity
NDR85_RS20030	COG3507	Belongs to the glycosyl hydrolase 43 family
NDR85_RS20045	COG2986	histidine ammonia-lyase
NDR85_RS20050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NDR85_RS20055	COG1228	amidohydrolase
NDR85_RS20060	COG0010	Belongs to the arginase family
NDR85_RS20065	COG0833	amino acid
NDR85_RS20070	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NDR85_RS20075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NDR85_RS20080	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NDR85_RS20085	COG2390	Transcriptional regulator
NDR85_RS20100	COG2079	MmgE PrpD family protein
NDR85_RS20105	COG1473	amidohydrolase
NDR85_RS20110	COG1126	abc transporter atp-binding protein
NDR85_RS20115	COG0765	amino acid transport
NDR85_RS20120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NDR85_RS20125	COG0456	acetyltransferase
NDR85_RS20130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NDR85_RS20140	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NDR85_RS20145	COG0561	phosphatase activity
NDR85_RS20175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NDR85_RS20180	COG5294	Protein conserved in bacteria
NDR85_RS20185	COG0577	efflux transmembrane transporter activity
NDR85_RS20190	COG1136	(ABC) transporter
NDR85_RS20195	COG2205	protein histidine kinase activity
NDR85_RS20200	COG0745	RESPONSE REGULATOR receiver
NDR85_RS20205	COG0191	fructose-bisphosphate aldolase activity
NDR85_RS20215	COG1082	Xylose isomerase domain protein TIM barrel
NDR85_RS20220	COG0673	inositol 2-dehydrogenase activity
NDR85_RS20225	COG2814	Major facilitator Superfamily
NDR85_RS20230	COG1082	Xylose isomerase domain protein TIM barrel
NDR85_RS20235	COG3962	Belongs to the TPP enzyme family
NDR85_RS20240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NDR85_RS20250	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS20255	COG1349	DNA-binding transcription factor activity
NDR85_RS20260	COG0667	Aldo Keto reductase
NDR85_RS20285	COG2814	Major facilitator Superfamily
NDR85_RS20290	COG0326	Molecular chaperone. Has ATPase activity
NDR85_RS20300	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS20305	COG1309	transcriptional regulator
NDR85_RS20310	COG1012	belongs to the aldehyde dehydrogenase family
NDR85_RS20315	COG1714	RDD family
NDR85_RS20320	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NDR85_RS20330	COG1714	RDD family
NDR85_RS20335	COG2311	Membrane
NDR85_RS20340	COG1917	Cupin 2, conserved barrel domain protein
NDR85_RS20345	COG1309	transcriptional regulator
NDR85_RS20350	COG1028	Short-chain dehydrogenase reductase Sdr
NDR85_RS20380	COG5039	Polysaccharide pyruvyl transferase
NDR85_RS20385	COG1929	Belongs to the glycerate kinase type-1 family
NDR85_RS20390	COG1802	Transcriptional regulator
NDR85_RS20395	COG1070	Carbohydrate kinase
NDR85_RS20400	COG2610	gluconate transmembrane transporter activity
NDR85_RS20405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NDR85_RS20410	COG0450	alkyl hydroperoxide reductase
NDR85_RS20415	COG3634	alkyl hydroperoxide reductase activity
NDR85_RS20435	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NDR85_RS20450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NDR85_RS20465	COG1063	alcohol dehydrogenase
NDR85_RS20485	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NDR85_RS20495	COG0457	Tetratricopeptide repeat
NDR85_RS20505	COG0010	Belongs to the arginase family
NDR85_RS20510	COG0833	amino acid
NDR85_RS20515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NDR85_RS20535	COG5658	integral membrane protein
NDR85_RS20540	COG0640	Transcriptional regulator
NDR85_RS20545	COG3829	transcription factor binding
NDR85_RS20550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NDR85_RS20555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NDR85_RS20560	COG4853	Protein conserved in bacteria
NDR85_RS20565	COG4863	YycH protein
NDR85_RS20570	COG5002	protein histidine kinase activity
NDR85_RS20575	COG0745	RESPONSE REGULATOR receiver
NDR85_RS20605	COG0346	lactoylglutathione lyase activity
NDR85_RS20610	COG0305	Participates in initiation and elongation during chromosome replication
NDR85_RS20625	COG3093	addiction module antidote protein HigA
NDR85_RS20630	COG2807	transmembrane transport
NDR85_RS20635	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NDR85_RS20640	COG0359	binds to the 23S rRNA
NDR85_RS20645	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NDR85_RS20650	COG4241	membrane
NDR85_RS20660	COG5577	PFAM Coat F domain
NDR85_RS20665	COG1733	regulation of RNA biosynthetic process
NDR85_RS20670	COG1227	inorganic diphosphatase activity
NDR85_RS20680	COG2271	Major facilitator Superfamily
NDR85_RS20700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NDR85_RS20710	COG0640	Transcriptional regulator
NDR85_RS20715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NDR85_RS20720	COG2409	Drug exporters of the RND superfamily
NDR85_RS20725	COG2197	response regulator
NDR85_RS20730	COG4585	Histidine kinase
NDR85_RS20745	COG0789	Transcriptional regulator
NDR85_RS20745	COG4978	Transcriptional regulator
NDR85_RS20750	COG1811	Na channel or pump
NDR85_RS20760	COG0789	Transcriptional regulator
NDR85_RS20765	COG0697	spore germination
NDR85_RS20795	COG1331	Highly conserved protein containing a thioredoxin domain
NDR85_RS20800	COG1522	sequence-specific DNA binding
NDR85_RS20815	COG0789	Transcriptional regulator
NDR85_RS20820	COG1331	Highly conserved protein containing a thioredoxin domain
NDR85_RS20825	COG1266	CAAX protease self-immunity
NDR85_RS20830	COG2814	Major facilitator Superfamily
NDR85_RS20830	COG0477	Major facilitator Superfamily
NDR85_RS20835	COG0110	maltose O-acetyltransferase activity
NDR85_RS20840	COG0346	lactoylglutathione lyase activity
NDR85_RS20845	COG1609	Transcriptional regulator
NDR85_RS20850	COG0708	Exodeoxyribonuclease III
NDR85_RS20860	COG0629	single-stranded DNA binding
NDR85_RS20865	COG0360	Binds together with S18 to 16S ribosomal RNA
NDR85_RS20870	COG0012	GTP binding
NDR85_RS20875	COG0243	molybdopterin cofactor binding
NDR85_RS20880	COG4481	Protein conserved in bacteria
NDR85_RS20885	COG3949	Membrane
NDR85_RS20895	COG1475	DNA binding
NDR85_RS20900	COG1192	Involved in chromosome partitioning
NDR85_RS20910	COG1475	DNA binding
NDR85_RS20915	COG0357	Ribosomal RNA small subunit methyltransferase G
NDR85_RS20920	COG0445	tRNA wobble uridine modification
NDR85_RS20925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NDR85_RS20930	COG1847	R3H domain protein
NDR85_RS20935	COG0706	membrane insertase activity
NDR85_RS20940	COG0594	ribonuclease P activity