locus-tag	class	description
DIC78_RS00005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS00010	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DIC78_RS00010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS00020	COG1649	PFAM Uncharacterised BCR, COG1649
DIC78_RS00030	COG1309	transcriptional regulator
DIC78_RS00035	COG1960	acyl-CoA dehydrogenase activity
DIC78_RS00040	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS00045	COG0439	Biotin carboxylase
DIC78_RS00050	COG0511	ligase activity, forming carbon-carbon bonds
DIC78_RS00055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIC78_RS00060	COG1024	Enoyl-CoA hydratase
DIC78_RS00065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIC78_RS00070	COG2404	hydrolase activity, acting on ester bonds
DIC78_RS00075	COG0586	Pfam SNARE associated Golgi protein
DIC78_RS00085	COG2246	polysaccharide biosynthetic process
DIC78_RS00095	COG3507	Belongs to the glycosyl hydrolase 43 family
DIC78_RS00100	COG5520	Belongs to the glycosyl hydrolase 30 family
DIC78_RS00115	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DIC78_RS00120	COG1115	amino acid carrier protein
DIC78_RS00130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIC78_RS00135	COG0187	DNA topoisomerase II activity
DIC78_RS00140	COG1832	CoA-binding protein
DIC78_RS00145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DIC78_RS00150	COG4841	protein insertion into membrane
DIC78_RS00160	COG0824	Thioesterase
DIC78_RS00180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS00185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DIC78_RS00200	COG0071	Belongs to the small heat shock protein (HSP20) family
DIC78_RS00210	COG4846	Membrane protein involved in cytochrome C biogenesis
DIC78_RS00215	COG2201	protein-glutamate methylesterase activity
DIC78_RS00220	COG0785	Cytochrome C biogenesis protein
DIC78_RS00230	COG3763	UPF0154 protein
DIC78_RS00240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DIC78_RS00245	COG4224	UPF0291 protein
DIC78_RS00250	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DIC78_RS00255	COG1388	LysM domain
DIC78_RS00260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DIC78_RS00275	COG0346	lactoylglutathione lyase activity
DIC78_RS00295	COG4195	phage-related replication protein
DIC78_RS00330	COG3832	glyoxalase III activity
DIC78_RS00340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIC78_RS00365	COG3655	Transcriptional regulator
DIC78_RS00370	COG3739	integral membrane protein
DIC78_RS00375	COG2720	vancomycin resistance protein
DIC78_RS00380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DIC78_RS00405	COG0726	polysaccharide deacetylase
DIC78_RS00435	COG0457	Tetratricopeptide repeat
DIC78_RS00445	COG2273	Hydrolase Family 16
DIC78_RS00480	COG0456	acetyltransferase
DIC78_RS00535	COG0583	DNA-binding transcription factor activity
DIC78_RS00540	COG0697	spore germination
DIC78_RS00550	COG1388	LysM domain
DIC78_RS00570	COG0174	glutamine synthetase
DIC78_RS00575	COG0789	Transcriptional regulator
DIC78_RS00580	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DIC78_RS00585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DIC78_RS00590	COG0464	growth
DIC78_RS00600	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS00605	COG4112	unkown
DIC78_RS00610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIC78_RS00615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DIC78_RS00620	COG1780	Probably involved in ribonucleotide reductase function
DIC78_RS00640	COG1923	regulation of RNA biosynthetic process
DIC78_RS00645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DIC78_RS00670	COG1764	response to oxidative stress
DIC78_RS00675	COG4195	phage-related replication protein
DIC78_RS00685	COG1404	Belongs to the peptidase S8 family
DIC78_RS00695	COG2124	cytochrome p450
DIC78_RS00700	COG3321	synthase
DIC78_RS00700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIC78_RS00700	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DIC78_RS00700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DIC78_RS00705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS00705	COG3321	synthase
DIC78_RS00705	COG4221	oxidoreductase activity
DIC78_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS00710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIC78_RS00710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIC78_RS00710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS00710	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS00710	COG3321	synthase
DIC78_RS00715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIC78_RS00715	COG0300	oxidoreductase activity
DIC78_RS00715	COG3321	synthase
DIC78_RS00715	COG4221	oxidoreductase activity
DIC78_RS00720	COG3321	synthase
DIC78_RS00720	COG0300	oxidoreductase activity
DIC78_RS00720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS00720	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS00725	COG1024	Enoyl-CoA hydratase
DIC78_RS00730	COG1024	Enoyl-CoA hydratase
DIC78_RS00735	COG3425	synthase
DIC78_RS00740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIC78_RS00745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIC78_RS00750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DIC78_RS00750	COG2070	2-Nitropropane dioxygenase
DIC78_RS00755	COG3321	synthase
DIC78_RS00760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DIC78_RS00765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS00770	COG3226	Transcriptional regulator
DIC78_RS00805	COG0582	viral genome integration into host DNA
DIC78_RS00815	COG4195	phage-related replication protein
DIC78_RS00845	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DIC78_RS00850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DIC78_RS00860	COG4550	Control of competence regulator ComK, YlbF/YmcA
DIC78_RS00865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIC78_RS00870	COG0156	8-amino-7-oxononanoate synthase activity
DIC78_RS00875	COG1063	alcohol dehydrogenase
DIC78_RS00880	COG2359	stage V sporulation protein S
DIC78_RS00885	COG1692	metallophosphoesterase
DIC78_RS00890	COG1418	mRNA catabolic process
DIC78_RS00895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIC78_RS00900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DIC78_RS00905	COG1546	Belongs to the CinA family
DIC78_RS00905	COG1058	Belongs to the CinA family
DIC78_RS00910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DIC78_RS00915	COG1426	Protein conserved in bacteria
DIC78_RS00930	COG0300	oxidoreductase activity
DIC78_RS00935	COG0612	Peptidase, M16
DIC78_RS00940	COG0612	Peptidase, M16
DIC78_RS00945	COG2814	Major facilitator Superfamily
DIC78_RS00950	COG2188	Transcriptional regulator
DIC78_RS00955	COG1674	ftsk spoiiie
DIC78_RS00955	COG4980	gas vesicle protein
DIC78_RS00965	COG0740	serine-type endopeptidase activity
DIC78_RS00970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIC78_RS00975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIC78_RS00980	COG0527	aspartate kinase activity
DIC78_RS00985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DIC78_RS00990	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DIC78_RS00995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIC78_RS01000	COG1873	PFAM PRC-barrel domain
DIC78_RS01005	COG0612	Peptidase, M16
DIC78_RS01010	COG0726	polysaccharide deacetylase
DIC78_RS01015	COG1185	polyribonucleotide nucleotidyltransferase activity
DIC78_RS01025	COG0196	riboflavin kinase activity
DIC78_RS01030	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DIC78_RS01035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DIC78_RS01040	COG1550	Protein conserved in bacteria
DIC78_RS01045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DIC78_RS01050	COG1358	cellular component organization or biogenesis
DIC78_RS01055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DIC78_RS01060	COG0195	Participates in both transcription termination and antitermination
DIC78_RS01065	COG0779	Required for maturation of 30S ribosomal subunits
DIC78_RS01070	COG2176	DNA-directed DNA polymerase activity
DIC78_RS01075	COG0442	prolyl-tRNA aminoacylation
DIC78_RS01080	COG0750	zinc metalloprotease
DIC78_RS01085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DIC78_RS01090	COG4589	Belongs to the CDS family
DIC78_RS01095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DIC78_RS01100	COG0233	cytoplasmic translational termination
DIC78_RS01105	COG0528	UMP kinase activity
DIC78_RS01110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DIC78_RS01115	COG0052	Belongs to the universal ribosomal protein uS2 family
DIC78_RS01125	COG1191	sigma factor activity
DIC78_RS01130	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DIC78_RS01135	COG1776	CheC inhibitor of MCP methylation
DIC78_RS01140	COG0835	chemotaxis
DIC78_RS01145	COG2198	Histidine kinase
DIC78_RS01145	COG0643	Histidine kinase
DIC78_RS01150	COG2201	protein-glutamate methylesterase activity
DIC78_RS01155	COG0455	bacterial-type flagellum organization
DIC78_RS01160	COG1419	protein localization to endoplasmic reticulum
DIC78_RS01165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DIC78_RS01170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DIC78_RS01175	COG1684	flagellar biosynthetic protein fliR
DIC78_RS01180	COG1987	bacterial-type flagellum assembly
DIC78_RS01185	COG1338	Plays a role in the flagellum-specific transport system
DIC78_RS01190	COG3190	flagellar
DIC78_RS01195	COG2201	protein-glutamate methylesterase activity
DIC78_RS01200	COG1776	CheC inhibitor of MCP methylation
DIC78_RS01200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DIC78_RS01205	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DIC78_RS01210	COG1580	Controls the rotational direction of flagella during chemotaxis
DIC78_RS01215	COG1582	Flagellar protein (FlbD)
DIC78_RS01220	COG4786	Flagellar basal body rod
DIC78_RS01225	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DIC78_RS01230	COG3144	bacterial-type flagellum assembly
DIC78_RS01235	COG3334	PFAM MgtE intracellular
DIC78_RS01240	COG2882	bacterial-type flagellum organization
DIC78_RS01245	COG1157	protein secretion by the type III secretion system
DIC78_RS01250	COG1317	bacterial-type flagellum organization
DIC78_RS01255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DIC78_RS01260	COG1766	The M ring may be actively involved in energy transduction
DIC78_RS01265	COG1677	Flagellar hook-basal body complex protein FliE
DIC78_RS01270	COG1558	bacterial-type flagellum-dependent cell motility
DIC78_RS01275	COG1815	bacterial-type flagellum-dependent cell motility
DIC78_RS01280	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DIC78_RS01285	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DIC78_RS01290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DIC78_RS01295	COG4974	Belongs to the 'phage' integrase family
DIC78_RS01300	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DIC78_RS01305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DIC78_RS01310	COG0758	DNA mediated transformation
DIC78_RS01315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DIC78_RS01320	COG0045	succinate-CoA ligase (ADP-forming) activity
DIC78_RS01325	COG2257	FlhB HrpN YscU SpaS Family
DIC78_RS01335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIC78_RS01340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DIC78_RS01345	COG0335	large ribosomal subunit rRNA binding
DIC78_RS01350	COG0336	Belongs to the RNA methyltransferase TrmD family
DIC78_RS01355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DIC78_RS01365	COG1837	Belongs to the UPF0109 family
DIC78_RS01370	COG0228	four-way junction DNA binding
DIC78_RS01375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DIC78_RS01380	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DIC78_RS01390	COG0552	protein localization to endoplasmic reticulum
DIC78_RS01395	COG1196	nuclear chromosome segregation
DIC78_RS01400	COG0571	ribonuclease III activity
DIC78_RS01410	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS01415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DIC78_RS01420	COG0416	fatty acid biosynthetic process
DIC78_RS01425	COG2050	protein possibly involved in aromatic compounds catabolism
DIC78_RS01425	COG1349	DNA-binding transcription factor activity
DIC78_RS01430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DIC78_RS01435	COG1760	l-serine dehydratase
DIC78_RS01440	COG1760	l-serine dehydratase
DIC78_RS01445	COG1461	Dihydroxyacetone kinase
DIC78_RS01450	COG1302	Protein conserved in bacteria
DIC78_RS01455	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DIC78_RS01465	COG1564	THIamine pyrophosphokinase
DIC78_RS01470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DIC78_RS01475	COG1162	GTPase activity
DIC78_RS01480	COG2815	serine threonine protein kinase
DIC78_RS01480	COG0515	serine threonine protein kinase
DIC78_RS01485	COG0631	protein serine/threonine phosphatase activity
DIC78_RS01490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DIC78_RS01495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DIC78_RS01495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DIC78_RS01500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DIC78_RS01505	COG0242	peptide deformylase activity
DIC78_RS01510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIC78_RS01515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DIC78_RS01520	COG1758	RNA polymerase activity
DIC78_RS01525	COG0194	GDP metabolic process
DIC78_RS01535	COG1561	YicC-like family, N-terminal region
DIC78_RS01540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DIC78_RS01545	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DIC78_RS01550	COG1648	precorrin-2 dehydrogenase activity
DIC78_RS01555	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DIC78_RS01560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DIC78_RS01565	COG0529	Catalyzes the synthesis of activated sulfate
DIC78_RS01570	COG2046	Belongs to the sulfate adenylyltransferase family
DIC78_RS01575	COG0306	phosphate transporter
DIC78_RS01580	COG0175	sulfate reduction
DIC78_RS01585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DIC78_RS01590	COG0284	orotidine-5'-phosphate decarboxylase activity
DIC78_RS01595	COG0167	dihydroorotate dehydrogenase activity
DIC78_RS01600	COG0543	2 iron, 2 sulfur cluster binding
DIC78_RS01605	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DIC78_RS01610	COG0505	Belongs to the CarA family
DIC78_RS01615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIC78_RS01620	COG0540	Belongs to the ATCase OTCase family
DIC78_RS01625	COG2233	PERMEase
DIC78_RS01630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DIC78_RS01640	COG0564	pseudouridine synthase activity
DIC78_RS01645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DIC78_RS01650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DIC78_RS01655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DIC78_RS01660	COG3599	regulation of cell shape
DIC78_RS01665	COG2302	S4 RNA-binding domain
DIC78_RS01670	COG0762	integral membrane protein
DIC78_RS01675	COG1799	cell septum assembly
DIC78_RS01680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DIC78_RS01685	COG1496	oxidoreductase activity
DIC78_RS01690	COG1873	PFAM PRC-barrel domain
DIC78_RS01700	COG1119	ATPase activity
DIC78_RS01705	COG1191	sigma factor activity
DIC78_RS01710	COG1191	sigma factor activity
DIC78_RS01720	COG1404	Belongs to the peptidase S8 family
DIC78_RS01720	COG4412	M6 family metalloprotease domain protein
DIC78_RS01725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DIC78_RS01730	COG0849	cell division
DIC78_RS01735	COG3856	small basic protein
DIC78_RS01740	COG3879	Bacterial protein of unknown function (DUF881)
DIC78_RS01745	COG3879	Bacterial protein of unknown function (DUF881)
DIC78_RS01750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DIC78_RS01755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DIC78_RS01760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIC78_RS01765	COG0772	Belongs to the SEDS family
DIC78_RS01770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DIC78_RS01775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIC78_RS01780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DIC78_RS01785	COG0768	penicillin binding
DIC78_RS01790	COG0768	penicillin binding
DIC78_RS01795	COG4839	cell division protein FtsL
DIC78_RS01800	COG0275	rRNA processing
DIC78_RS01805	COG2001	Belongs to the MraZ family
DIC78_RS01810	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DIC78_RS01815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DIC78_RS01820	COG0454	-acetyltransferase
DIC78_RS01835	COG1399	metal-binding, possibly nucleic acid-binding protein
DIC78_RS01840	COG1323	Belongs to the UPF0348 family
DIC78_RS01850	COG3480	Lon protease (S16) C-terminal proteolytic domain
DIC78_RS01855	COG1752	Esterase of the alpha-beta hydrolase superfamily
DIC78_RS01860	COG3314	Sporulation integral membrane protein YlbJ
DIC78_RS01865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DIC78_RS01870	COG0742	ribosomal rna small subunit methyltransferase
DIC78_RS01875	COG4471	UPF0298 protein
DIC78_RS01880	COG3679	Belongs to the UPF0342 family
DIC78_RS01895	COG2340	Cysteine-rich secretory protein family
DIC78_RS01900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DIC78_RS01910	COG3336	cytochrome c oxidase
DIC78_RS01915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DIC78_RS01920	COG1845	cytochrome c oxidase, subunit III
DIC78_RS01925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DIC78_RS01930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DIC78_RS01930	COG2010	Cytochrome c
DIC78_RS01935	COG0109	protoheme IX farnesyltransferase activity
DIC78_RS01940	COG1612	heme a metabolic process
DIC78_RS01945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DIC78_RS01950	COG0772	Belongs to the SEDS family
DIC78_RS01955	COG4838	Belongs to the UPF0358 family
DIC78_RS01960	COG2066	Belongs to the glutaminase family
DIC78_RS01965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DIC78_RS01970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DIC78_RS01980	COG4896	Protein conserved in bacteria
DIC78_RS01990	COG1217	gtp-binding protein TYPA
DIC78_RS02030	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DIC78_RS02040	COG0483	inositol monophosphate 1-phosphatase activity
DIC78_RS02050	COG4493	Belongs to the UPF0637 family
DIC78_RS02055	COG4476	Belongs to the UPF0223 family
DIC78_RS02060	COG1982	Orn Lys Arg decarboxylase major
DIC78_RS02070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS02075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIC78_RS02080	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIC78_RS02085	COG0022	dehydrogenase e1 component
DIC78_RS02090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DIC78_RS02095	COG0497	DNA recombination
DIC78_RS02105	COG0242	peptide deformylase activity
DIC78_RS02110	COG0561	phosphatase activity
DIC78_RS02115	COG5503	Protein of unknown function (DUF1447)
DIC78_RS02120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DIC78_RS02125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DIC78_RS02130	COG0569	domain protein
DIC78_RS02135	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DIC78_RS02135	COG2105	PFAM AIG2 family protein
DIC78_RS02140	COG3852	Histidine kinase
DIC78_RS02145	COG2002	toxin-antitoxin pair type II binding
DIC78_RS02155	COG1077	Cell shape determining protein MreB Mrl
DIC78_RS02165	COG2309	aminopeptidase activity
DIC78_RS02170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DIC78_RS02175	COG0488	(ABC) transporter
DIC78_RS02185	COG0681	Belongs to the peptidase S26 family
DIC78_RS02190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS02190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DIC78_RS02190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DIC78_RS02195	COG1105	Belongs to the carbohydrate kinase PfkB family
DIC78_RS02200	COG1349	DNA-binding transcription factor activity
DIC78_RS02205	COG0577	efflux transmembrane transporter activity
DIC78_RS02210	COG1136	(ABC) transporter
DIC78_RS02215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIC78_RS02225	COG1132	(ABC) transporter
DIC78_RS02230	COG1132	(ABC) transporter
DIC78_RS02235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DIC78_RS02240	COG0314	molybdopterin synthase activity
DIC78_RS02245	COG1763	Mo-molybdopterin cofactor biosynthetic process
DIC78_RS02250	COG0303	'Molybdopterin
DIC78_RS02255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DIC78_RS02260	COG0746	molybdenum cofactor guanylyltransferase activity
DIC78_RS02275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS02280	COG0450	alkyl hydroperoxide reductase
DIC78_RS02285	COG0668	transmembrane transport
DIC78_RS02295	COG1473	amidohydrolase
DIC78_RS02300	COG2171	N-acyltransferase activity
DIC78_RS02305	COG0716	FMN binding
DIC78_RS02315	COG0716	FMN binding
DIC78_RS02320	COG0583	DNA-binding transcription factor activity
DIC78_RS02325	COG0517	IMP dehydrogenase activity
DIC78_RS02335	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DIC78_RS02340	COG4703	Protein of unknown function (DUF1797)
DIC78_RS02345	COG3546	catalase activity
DIC78_RS02350	COG2200	EAL domain
DIC78_RS02360	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS02365	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS02370	COG1408	metallophosphoesterase
DIC78_RS02375	COG1376	ErfK ybiS ycfS ynhG family protein
DIC78_RS02380	COG2814	Major facilitator Superfamily
DIC78_RS02390	COG0784	Response regulator, receiver
DIC78_RS02390	COG0835	chemotaxis
DIC78_RS02400	COG0436	Aminotransferase
DIC78_RS02405	COG4191	Histidine kinase
DIC78_RS02410	COG0768	penicillin binding
DIC78_RS02415	COG2340	Cysteine-rich secretory protein family
DIC78_RS02420	COG2084	Dehydrogenase
DIC78_RS02425	COG0840	transmembrane signaling receptor activity
DIC78_RS02435	COG1533	DNA photolyase activity
DIC78_RS02445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DIC78_RS02450	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS02455	COG2190	(PTS) system
DIC78_RS02455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS02455	COG1263	PTS System
DIC78_RS02460	COG3711	transcriptional antiterminator
DIC78_RS02465	COG1609	Transcriptional regulator
DIC78_RS02470	COG0006	proline dipeptidase activity
DIC78_RS02480	COG2217	Heavy metal translocating P-type atpase
DIC78_RS02485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS02490	COG2244	polysaccharide biosynthetic process
DIC78_RS02495	COG3773	Cell wall hydrolase
DIC78_RS02505	COG4873	Protein conserved in bacteria
DIC78_RS02520	COG3858	chitin binding
DIC78_RS02525	COG1388	LysM domain
DIC78_RS02530	COG1388	LysM domain
DIC78_RS02530	COG4641	Protein conserved in bacteria
DIC78_RS02535	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DIC78_RS02540	COG0602	queuosine metabolic process
DIC78_RS02545	COG0720	synthase
DIC78_RS02550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DIC78_RS02555	COG3949	Membrane
DIC78_RS02560	COG0542	response to heat
DIC78_RS02565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DIC78_RS02570	COG1360	Flagellar Motor Protein
DIC78_RS02575	COG1846	Transcriptional regulator
DIC78_RS02585	COG3852	Histidine kinase
DIC78_RS02600	COG3339	Conserved Protein
DIC78_RS02605	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DIC78_RS02610	COG0235	Class ii aldolase
DIC78_RS02615	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DIC78_RS02620	COG1850	ribulose-bisphosphate carboxylase activity
DIC78_RS02625	COG0436	Aminotransferase
DIC78_RS02630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIC78_RS02635	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DIC78_RS02640	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DIC78_RS02650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DIC78_RS02655	COG5002	protein histidine kinase activity
DIC78_RS02660	COG3594	Acyltransferase
DIC78_RS02675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DIC78_RS02680	COG0501	Belongs to the peptidase M48B family
DIC78_RS02700	COG1191	sigma factor activity
DIC78_RS02705	COG0861	Integral membrane protein TerC family
DIC78_RS02710	COG0586	Pfam SNARE associated Golgi protein
DIC78_RS02715	COG3300	MHYT domain
DIC78_RS02715	COG5001	Diguanylate cyclase
DIC78_RS02720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DIC78_RS02725	COG1793	dna ligase
DIC78_RS02725	COG3285	dna ligase
DIC78_RS02730	COG0463	Glycosyl transferase, family 2
DIC78_RS02740	COG1408	metallophosphoesterase
DIC78_RS02745	COG0726	polysaccharide deacetylase
DIC78_RS02750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIC78_RS02755	COG1846	Transcriptional regulator
DIC78_RS02770	COG0789	Transcriptional regulator
DIC78_RS02775	COG2239	Acts as a magnesium transporter
DIC78_RS02790	COG3212	peptidase
DIC78_RS02795	COG3212	peptidase
DIC78_RS02800	COG3850	Histidine kinase
DIC78_RS02800	COG5002	protein histidine kinase activity
DIC78_RS02805	COG0745	RESPONSE REGULATOR receiver
DIC78_RS02815	COG4721	ABC-type cobalt transport system, permease component
DIC78_RS02820	COG1122	ATPase activity
DIC78_RS02825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIC78_RS02830	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS02835	COG1404	Belongs to the peptidase S8 family
DIC78_RS02840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DIC78_RS02845	COG0406	alpha-ribazole phosphatase activity
DIC78_RS02850	COG0590	tRNA wobble adenosine to inosine editing
DIC78_RS02855	COG0457	Tetratricopeptide repeat
DIC78_RS02855	COG0463	Glycosyl transferase, family 2
DIC78_RS02860	COG1764	response to oxidative stress
DIC78_RS02865	COG1846	Transcriptional regulator
DIC78_RS02870	COG1764	response to oxidative stress
DIC78_RS02875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DIC78_RS02880	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DIC78_RS02885	COG0788	formyltetrahydrofolate deformylase activity
DIC78_RS02890	COG2076	Multidrug Resistance protein
DIC78_RS02895	COG2076	Multidrug Resistance protein
DIC78_RS02900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS02905	COG2318	DinB family
DIC78_RS02910	COG2323	membrane
DIC78_RS02920	COG1017	nitric oxide dioxygenase activity
DIC78_RS02920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DIC78_RS02925	COG1607	acyl-coa hydrolase
DIC78_RS02930	COG1834	amidinotransferase
DIC78_RS02935	COG2706	6-phosphogluconolactonase activity
DIC78_RS02940	COG4608	Belongs to the ABC transporter superfamily
DIC78_RS02945	COG0791	NLP P60 protein
DIC78_RS02950	COG4948	Mandelate Racemase Muconate Lactonizing
DIC78_RS02955	COG1619	proteins homologs of microcin C7 resistance protein MccF
DIC78_RS02960	COG4166	transmembrane transport
DIC78_RS02965	COG0444	Belongs to the ABC transporter superfamily
DIC78_RS02970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIC78_RS02975	COG0601	transmembrane transport
DIC78_RS02980	COG2362	D-Aminopeptidase
DIC78_RS02985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DIC78_RS02990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIC78_RS02995	COG0463	Glycosyl transferase, family 2
DIC78_RS03000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DIC78_RS03005	COG0346	lactoylglutathione lyase activity
DIC78_RS03010	COG0531	amino acid
DIC78_RS03015	COG1392	Phosphate transport regulator
DIC78_RS03020	COG0306	phosphate transporter
DIC78_RS03040	COG5632	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS03040	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS03080	COG3778	Protein conserved in bacteria
DIC78_RS03085	COG3299	homolog of phage Mu protein gp47
DIC78_RS03090	COG3628	GPW Gp25 family protein
DIC78_RS03100	COG4193	domain, Protein
DIC78_RS03105	COG1652	LysM domain
DIC78_RS03110	COG3953	SLT domain
DIC78_RS03110	COG5412	phage tail tape measure protein
DIC78_RS03160	COG4653	Phage capsid family
DIC78_RS03165	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DIC78_RS03170	COG5518	Phage portal protein
DIC78_RS03175	COG1783	phage Terminase large subunit
DIC78_RS03180	COG3728	DNA packaging
DIC78_RS03180	COG5484	DNA packaging
DIC78_RS03185	COG1595	DNA-templated transcription, initiation
DIC78_RS03205	COG1484	DNA-dependent DNA replication
DIC78_RS03210	COG1522	sequence-specific DNA binding
DIC78_RS03220	COG1396	sequence-specific DNA binding
DIC78_RS03225	COG2856	Zn peptidase
DIC78_RS03230	COG3546	catalase activity
DIC78_RS03235	COG4195	phage-related replication protein
DIC78_RS03245	COG1388	LysM domain
DIC78_RS03245	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS03245	COG5632	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS03250	COG2350	Protein conserved in bacteria
DIC78_RS03260	COG0457	Tetratricopeptide repeat
DIC78_RS03265	COG2318	DinB family
DIC78_RS03270	COG0730	response to heat
DIC78_RS03275	COG2721	sulfolactate sulfo-lyase activity
DIC78_RS03280	COG0246	Mannitol dehydrogenase
DIC78_RS03285	COG1609	Transcriptional regulator
DIC78_RS03290	COG2271	Major facilitator Superfamily
DIC78_RS03295	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS03300	COG1312	Catalyzes the dehydration of D-mannonate
DIC78_RS03305	COG1063	alcohol dehydrogenase
DIC78_RS03310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DIC78_RS03315	COG2211	Major facilitator Superfamily
DIC78_RS03320	COG1904	glucuronate isomerase
DIC78_RS03325	COG1252	NADH dehydrogenase
DIC78_RS03335	COG4297	protein containing double-stranded beta helix domain
DIC78_RS03340	COG0697	spore germination
DIC78_RS03345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DIC78_RS03350	COG0390	transport system, permease component
DIC78_RS03355	COG1587	Uroporphyrinogen-III synthase
DIC78_RS03370	COG1819	glycosyl
DIC78_RS03375	COG2124	cytochrome p450
DIC78_RS03385	COG1051	belongs to the nudix hydrolase family
DIC78_RS03395	COG2427	Protein of unknown function (DUF1641)
DIC78_RS03400	COG3383	formate dehydrogenase (NAD+) activity
DIC78_RS03410	COG2205	protein histidine kinase activity
DIC78_RS03415	COG5504	Zn-dependent protease
DIC78_RS03430	COG0726	polysaccharide deacetylase
DIC78_RS03440	COG0109	protoheme IX farnesyltransferase activity
DIC78_RS03460	COG0789	Transcriptional regulator
DIC78_RS03470	COG0697	spore germination
DIC78_RS03475	COG0583	DNA-binding transcription factor activity
DIC78_RS03480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS03500	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS03535	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DIC78_RS03545	COG0457	Tetratricopeptide repeat
DIC78_RS03605	COG5505	Protein of unknown function (DUF819)
DIC78_RS03610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS03615	COG0626	cystathionine gamma-synthase activity
DIC78_RS03620	COG0626	cystathionine gamma-synthase activity
DIC78_RS03625	COG2382	esterase
DIC78_RS03630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DIC78_RS03635	COG2153	protein acetylation
DIC78_RS03645	COG0210	DNA helicase
DIC78_RS03700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DIC78_RS03705	COG0351	phosphomethylpyrimidine kinase
DIC78_RS03710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DIC78_RS03715	COG2022	thiamine diphosphate biosynthetic process
DIC78_RS03720	COG2104	thiamine diphosphate biosynthetic process
DIC78_RS03725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIC78_RS03730	COG0352	thiamine-phosphate diphosphorylase activity
DIC78_RS03735	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DIC78_RS03740	COG0569	domain protein
DIC78_RS03740	COG0475	glutathione-regulated potassium exporter activity
DIC78_RS03745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DIC78_RS03750	COG0564	pseudouridine synthase activity
DIC78_RS03755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIC78_RS03760	COG2357	RelA SpoT domain protein
DIC78_RS03770	COG4116	CYTH
DIC78_RS03775	COG0741	lytic transglycosylase activity
DIC78_RS03780	COG2346	COG2346, Truncated hemoglobins
DIC78_RS03785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DIC78_RS03800	COG1164	Oligoendopeptidase f
DIC78_RS03805	COG4469	Competence protein
DIC78_RS03810	COG4862	establishment of competence for transformation
DIC78_RS03820	COG0861	Integral membrane protein TerC family
DIC78_RS03825	COG1393	Belongs to the ArsC family
DIC78_RS03830	COG0456	acetyltransferase
DIC78_RS03835	COG2814	Major facilitator Superfamily
DIC78_RS03840	COG4608	Belongs to the ABC transporter superfamily
DIC78_RS03845	COG0444	Belongs to the ABC transporter superfamily
DIC78_RS03850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIC78_RS03855	COG0601	transmembrane transport
DIC78_RS03860	COG4166	transmembrane transport
DIC78_RS03870	COG0180	Tryptophanyl-tRNA synthetase
DIC78_RS03880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIC78_RS03885	COG0601	transmembrane transport
DIC78_RS03895	COG4608	Belongs to the ABC transporter superfamily
DIC78_RS03900	COG0444	Belongs to the ABC transporter superfamily
DIC78_RS03905	COG5504	Zn-dependent protease
DIC78_RS03910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIC78_RS03915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIC78_RS03930	COG1744	ABC transporter substrate-binding protein PnrA-like
DIC78_RS03940	COG2267	carboxylic ester hydrolase activity
DIC78_RS03955	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DIC78_RS03960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DIC78_RS03965	COG0505	Belongs to the CarA family
DIC78_RS03970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIC78_RS03980	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DIC78_RS03985	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DIC78_RS03990	COG2271	Major facilitator Superfamily
DIC78_RS03995	COG0277	FAD linked oxidase domain protein
DIC78_RS04005	COG2151	metal-sulfur cluster biosynthetic enzyme
DIC78_RS04010	COG1073	alpha beta
DIC78_RS04015	COG0561	phosphatase activity
DIC78_RS04030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS04035	COG1307	EDD domain protein, DegV family
DIC78_RS04040	COG3227	Zinc metalloprotease (Elastase)
DIC78_RS04055	COG1695	Transcriptional regulator
DIC78_RS04075	COG2996	Protein conserved in bacteria
DIC78_RS04080	COG1666	GTP binding
DIC78_RS04085	COG0646	methionine synthase
DIC78_RS04085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DIC78_RS04090	COG2153	protein acetylation
DIC78_RS04095	COG0454	-acetyltransferase
DIC78_RS04100	COG2814	Major facilitator Superfamily
DIC78_RS04105	COG4948	Mandelate Racemase Muconate Lactonizing
DIC78_RS04110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS04115	COG1809	phosphosulfolactate synthase activity
DIC78_RS04120	COG2045	Belongs to the ComB family
DIC78_RS04125	COG0175	sulfate reduction
DIC78_RS04130	COG2046	Belongs to the sulfate adenylyltransferase family
DIC78_RS04135	COG0529	Catalyzes the synthesis of activated sulfate
DIC78_RS04140	COG2267	carboxylic ester hydrolase activity
DIC78_RS04145	COG1357	PFAM Pentapeptide repeats (8 copies)
DIC78_RS04150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS04155	COG1279	arginine transmembrane transporter activity
DIC78_RS04160	COG2318	DinB family
DIC78_RS04165	COG0673	inositol 2-dehydrogenase activity
DIC78_RS04170	COG1609	Transcriptional regulator
DIC78_RS04175	COG1917	Cupin 2, conserved barrel domain protein
DIC78_RS04175	COG2207	Transcriptional regulator
DIC78_RS04180	COG0534	Mate efflux family protein
DIC78_RS04185	COG1562	ergosterol biosynthetic process
DIC78_RS04190	COG2318	DinB family
DIC78_RS04195	COG0367	asparagine synthase
DIC78_RS04205	COG1404	Belongs to the peptidase S8 family
DIC78_RS04215	COG0179	Fumarylacetoacetate (FAA) hydrolase
DIC78_RS04220	COG5337	Spore coat protein CotH
DIC78_RS04260	COG1403	HNH endonuclease
DIC78_RS04265	COG0419	ATPase involved in DNA repair
DIC78_RS04270	COG0420	3'-5' exonuclease activity
DIC78_RS04275	COG1074	ATP-dependent DNA helicase activity
DIC78_RS04280	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DIC78_RS04285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DIC78_RS04295	COG4533	DNA binding
DIC78_RS04300	COG0477	Major facilitator Superfamily
DIC78_RS04300	COG2814	Major facilitator Superfamily
DIC78_RS04305	COG3180	Ammonia monooxygenase
DIC78_RS04310	COG1609	Transcriptional regulator
DIC78_RS04315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIC78_RS04320	COG0561	phosphatase activity
DIC78_RS04325	COG0673	inositol 2-dehydrogenase activity
DIC78_RS04330	COG0738	Major facilitator superfamily
DIC78_RS04340	COG1846	Transcriptional regulator
DIC78_RS04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIC78_RS04350	COG0681	Belongs to the peptidase S26 family
DIC78_RS04355	COG0398	Pfam SNARE associated Golgi protein
DIC78_RS04370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIC78_RS04385	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS04395	COG4903	ComK protein
DIC78_RS04405	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS04410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIC78_RS04410	COG0723	plastoquinol--plastocyanin reductase activity
DIC78_RS04415	COG0840	transmembrane signaling receptor activity
DIC78_RS04420	COG1268	BioY protein
DIC78_RS04425	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS04430	COG0183	Belongs to the thiolase family
DIC78_RS04435	COG0406	alpha-ribazole phosphatase activity
DIC78_RS04440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DIC78_RS04445	COG0604	alcohol dehydrogenase
DIC78_RS04450	COG0456	acetyltransferase
DIC78_RS04455	COG1404	Belongs to the peptidase S8 family
DIC78_RS04460	COG0501	Belongs to the peptidase M48B family
DIC78_RS04470	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS04475	COG0702	epimerase
DIC78_RS04480	COG0095	Lipoate-protein ligase
DIC78_RS04485	COG1234	tRNA 3'-trailer cleavage
DIC78_RS04495	COG1301	dicarboxylic acid transport
DIC78_RS04500	COG4405	Protein conserved in bacteria
DIC78_RS04505	COG1363	Peptidase, m42
DIC78_RS04515	COG4377	Putative membrane peptidase family (DUF2324)
DIC78_RS04520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIC78_RS04525	COG1511	domain protein
DIC78_RS04530	COG1309	transcriptional regulator
DIC78_RS04535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DIC78_RS04540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DIC78_RS04545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DIC78_RS04550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIC78_RS04555	COG2329	Antibiotic biosynthesis monooxygenase
DIC78_RS04565	COG3069	C4-dicarboxylate transmembrane transporter activity
DIC78_RS04570	COG1473	amidohydrolase
DIC78_RS04580	COG4473	ABC transporter
DIC78_RS04585	COG1131	(ABC) transporter
DIC78_RS04590	COG0537	adenosine 5'-monophosphoramidase activity
DIC78_RS04595	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DIC78_RS04610	COG4980	gas vesicle protein
DIC78_RS04615	COG1846	Transcriptional regulator
DIC78_RS04645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DIC78_RS04655	COG3481	metal-dependent phosphohydrolase, HD sub domain
DIC78_RS04660	COG4717	serine-type aminopeptidase activity
DIC78_RS04665	COG0420	3'-5' exonuclease activity
DIC78_RS04670	COG1668	transmembrane transport
DIC78_RS04675	COG4152	abc transporter atp-binding protein
DIC78_RS04685	COG1024	Enoyl-CoA hydratase
DIC78_RS04695	COG0490	domain, Protein
DIC78_RS04700	COG0475	glutathione-regulated potassium exporter activity
DIC78_RS04705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DIC78_RS04710	COG0561	phosphatase activity
DIC78_RS04715	COG4335	DNA alkylation repair
DIC78_RS04720	COG3679	Belongs to the UPF0342 family
DIC78_RS04725	COG4399	Belongs to the UPF0754 family
DIC78_RS04730	COG0189	ligase activity
DIC78_RS04735	COG0189	ligase activity
DIC78_RS04755	COG0702	epimerase
DIC78_RS04760	COG1132	(ABC) transporter
DIC78_RS04765	COG1132	(ABC) transporter
DIC78_RS04775	COG0589	response to stress
DIC78_RS04780	COG1757	Na H antiporter
DIC78_RS04785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIC78_RS04790	COG0726	polysaccharide deacetylase
DIC78_RS04795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DIC78_RS04800	COG0668	transmembrane transport
DIC78_RS04810	COG0584	glycerophosphoryl diester phosphodiesterase
DIC78_RS04815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIC78_RS04820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DIC78_RS04825	COG1253	flavin adenine dinucleotide binding
DIC78_RS04830	COG0436	Aminotransferase
DIC78_RS04835	COG0789	Transcriptional regulator
DIC78_RS04840	COG1253	flavin adenine dinucleotide binding
DIC78_RS04845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIC78_RS04850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIC78_RS04855	COG0204	Acyl-transferase
DIC78_RS04860	COG0667	Aldo Keto reductase
DIC78_RS04865	COG1595	DNA-templated transcription, initiation
DIC78_RS04880	COG0456	acetyltransferase
DIC78_RS04885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS04890	COG0733	neurotransmitter:sodium symporter activity
DIC78_RS04895	COG0531	amino acid
DIC78_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS04905	COG0372	Belongs to the citrate synthase family
DIC78_RS04910	COG0583	DNA-binding transcription factor activity
DIC78_RS04915	COG0791	NLP P60 protein
DIC78_RS04915	COG1388	LysM domain
DIC78_RS04920	COG1785	Belongs to the alkaline phosphatase family
DIC78_RS04925	COG2719	SpoVR family
DIC78_RS04930	COG0668	transmembrane transport
DIC78_RS04935	COG1959	2 iron, 2 sulfur cluster binding
DIC78_RS04940	COG0791	NLP P60 protein
DIC78_RS04940	COG1388	LysM domain
DIC78_RS04960	COG0431	NADPH-dependent FMN reductase
DIC78_RS04965	COG2197	response regulator
DIC78_RS04970	COG2203	Gaf domain
DIC78_RS04970	COG4585	Histidine kinase
DIC78_RS04975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIC78_RS04980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DIC78_RS04985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DIC78_RS04990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DIC78_RS04995	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DIC78_RS05000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIC78_RS05010	COG3153	acetyltransferase
DIC78_RS05010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DIC78_RS05015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DIC78_RS05020	COG0517	IMP dehydrogenase activity
DIC78_RS05030	COG0564	pseudouridine synthase activity
DIC78_RS05035	COG3764	Sortase (surface protein transpeptidase)
DIC78_RS05040	COG4085	toxin activity
DIC78_RS05040	COG0737	Belongs to the 5'-nucleotidase family
DIC78_RS05040	COG1525	nuclease
DIC78_RS05045	COG5577	PFAM Coat F domain
DIC78_RS05065	COG1823	symporter activity
DIC78_RS05070	COG3706	GGDEF domain
DIC78_RS05075	COG1464	Belongs to the NlpA lipoprotein family
DIC78_RS05085	COG1278	Cold shock
DIC78_RS05090	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DIC78_RS05095	COG1131	(ABC) transporter
DIC78_RS05100	COG1131	(ABC) transporter
DIC78_RS05105	COG1725	Transcriptional regulator
DIC78_RS05120	COG0655	NAD(P)H dehydrogenase (quinone) activity
DIC78_RS05125	COG2814	Major facilitator Superfamily
DIC78_RS05130	COG1566	PFAM secretion protein HlyD family protein
DIC78_RS05135	COG1846	Transcriptional regulator
DIC78_RS05140	COG2718	Belongs to the UPF0229 family
DIC78_RS05145	COG2766	serine protein kinase
DIC78_RS05150	COG1664	Polymer-forming cytoskeletal
DIC78_RS05155	COG1664	Polymer-forming cytoskeletal
DIC78_RS05160	COG0789	Transcriptional regulator
DIC78_RS05165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DIC78_RS05175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DIC78_RS05180	COG3382	B3 4 domain protein
DIC78_RS05190	COG1476	TRANSCRIPTIONal
DIC78_RS05200	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DIC78_RS05210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS05215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIC78_RS05220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DIC78_RS05225	COG1116	anion transmembrane transporter activity
DIC78_RS05230	COG0753	catalase activity
DIC78_RS05245	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DIC78_RS05250	COG3340	Belongs to the peptidase S51 family
DIC78_RS05260	COG5577	PFAM Coat F domain
DIC78_RS05265	COG1063	alcohol dehydrogenase
DIC78_RS05275	COG4326	sporulation control protein
DIC78_RS05385	COG0735	belongs to the Fur family
DIC78_RS05390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DIC78_RS05395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DIC78_RS05400	COG4129	membrane
DIC78_RS05405	COG1132	(ABC) transporter
DIC78_RS05410	COG3557	Belongs to the UPF0374 family
DIC78_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS05435	COG1194	a g-specific adenine glycosylase
DIC78_RS05440	COG1988	membrane-bound metal-dependent
DIC78_RS05445	COG4485	Bacterial membrane protein, YfhO
DIC78_RS05450	COG0463	Glycosyl transferase, family 2
DIC78_RS05455	COG0596	Alpha beta hydrolase
DIC78_RS05460	COG5658	integral membrane protein
DIC78_RS05465	COG3103	Sh3 type 3 domain protein
DIC78_RS05470	COG1476	TRANSCRIPTIONal
DIC78_RS05490	COG2814	Major facilitator Superfamily
DIC78_RS05500	COG2137	regulation of response to DNA damage stimulus
DIC78_RS05505	COG1090	epimerase
DIC78_RS05520	COG0778	Nitroreductase
DIC78_RS05525	COG0384	phenazine biosynthesis protein PhzF
DIC78_RS05530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS05535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS05540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIC78_RS05545	COG0392	lysyltransferase activity
DIC78_RS05545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DIC78_RS05550	COG1846	Transcriptional regulator
DIC78_RS05555	COG2814	Major facilitator Superfamily
DIC78_RS05565	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DIC78_RS05575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DIC78_RS05580	COG1695	Transcriptional regulator
DIC78_RS05585	COG0842	Transport permease protein
DIC78_RS05590	COG1511	domain protein
DIC78_RS05590	COG0842	Transport permease protein
DIC78_RS05595	COG1131	(ABC) transporter
DIC78_RS05600	COG2197	response regulator
DIC78_RS05605	COG4585	Histidine kinase
DIC78_RS05610	COG0673	inositol 2-dehydrogenase activity
DIC78_RS05615	COG1082	Xylose isomerase domain protein TIM barrel
DIC78_RS05620	COG2814	Major facilitator Superfamily
DIC78_RS05625	COG4977	sequence-specific DNA binding
DIC78_RS05625	COG1917	Cupin 2, conserved barrel domain protein
DIC78_RS05630	COG2514	catechol 2,3-dioxygenase activity
DIC78_RS05635	COG2259	Doxx family
DIC78_RS05640	COG1132	(ABC) transporter
DIC78_RS05645	COG1132	(ABC) transporter
DIC78_RS05650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS05650	COG1263	PTS System
DIC78_RS05655	COG1737	Transcriptional regulator
DIC78_RS05660	COG1486	melibiose metabolic process
DIC78_RS05665	COG4842	Belongs to the WXG100 family
DIC78_RS05690	COG1742	UPF0060 membrane protein
DIC78_RS05700	COG3284	Transcriptional regulator
DIC78_RS05705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIC78_RS05710	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIC78_RS05715	COG0022	dehydrogenase e1 component
DIC78_RS05720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DIC78_RS05730	COG4637	Psort location Cytoplasmic, score
DIC78_RS05745	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DIC78_RS05755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DIC78_RS05770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIC78_RS05775	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DIC78_RS05780	COG0598	Magnesium transport protein CorA
DIC78_RS05785	COG2084	Dehydrogenase
DIC78_RS05790	COG0726	polysaccharide deacetylase
DIC78_RS05800	COG0535	radical SAM domain protein
DIC78_RS05805	COG0668	transmembrane transport
DIC78_RS05815	COG0387	Pfam Sodium calcium exchanger
DIC78_RS05820	COG0477	Major facilitator Superfamily
DIC78_RS05825	COG1295	ribonuclease BN
DIC78_RS05830	COG4980	gas vesicle protein
DIC78_RS05835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIC78_RS05840	COG4840	Belongs to the UPF0435 family
DIC78_RS05845	COG2814	Major facilitator Superfamily
DIC78_RS05850	COG0693	protein deglycase activity
DIC78_RS05855	COG0737	Belongs to the 5'-nucleotidase family
DIC78_RS05860	COG0778	Nitroreductase
DIC78_RS05865	COG2188	Transcriptional regulator
DIC78_RS05870	COG0366	Alpha amylase catalytic
DIC78_RS05875	COG1263	PTS System
DIC78_RS05875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS05880	COG1115	amino acid carrier protein
DIC78_RS05890	COG1368	sulfuric ester hydrolase activity
DIC78_RS05900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS05900	COG1263	PTS System
DIC78_RS05905	COG0024	Methionine aminopeptidase
DIC78_RS05925	COG2258	MOSC domain
DIC78_RS05930	COG1254	Belongs to the acylphosphatase family
DIC78_RS05935	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DIC78_RS05940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS05945	COG2851	Citrate transporter
DIC78_RS05950	COG3181	Tripartite tricarboxylate transporter family receptor
DIC78_RS05955	COG4565	transcriptional regulatory protein
DIC78_RS05960	COG3290	protein histidine kinase activity
DIC78_RS05970	COG0463	Glycosyl transferase, family 2
DIC78_RS05990	COG0471	metal ion transport
DIC78_RS05995	COG3866	Pectate lyase
DIC78_RS06010	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DIC78_RS06015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS06020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS06025	COG1120	ATPase activity
DIC78_RS06030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DIC78_RS06035	COG2211	Major facilitator Superfamily
DIC78_RS06045	COG2130	NADP-dependent
DIC78_RS06050	COG0456	acetyltransferase
DIC78_RS06055	COG0513	Belongs to the DEAD box helicase family
DIC78_RS06060	COG0488	(ABC) transporter
DIC78_RS06075	COG2814	Major facilitator Superfamily
DIC78_RS06080	COG0789	Transcriptional regulator
DIC78_RS06090	COG0488	(ABC) transporter
DIC78_RS06095	COG0840	transmembrane signaling receptor activity
DIC78_RS06100	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS06105	COG0531	amino acid
DIC78_RS06110	COG1011	Hydrolase
DIC78_RS06115	COG2223	nitrite transmembrane transporter activity
DIC78_RS06120	COG1442	glycosyl transferase family 8
DIC78_RS06125	COG1216	Glycosyl transferase, family 2
DIC78_RS06130	COG1442	glycosyl transferase family 8
DIC78_RS06135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIC78_RS06140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DIC78_RS06145	COG1368	sulfuric ester hydrolase activity
DIC78_RS06150	COG2124	cytochrome p450
DIC78_RS06150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DIC78_RS06160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIC78_RS06165	COG1846	Transcriptional regulator
DIC78_RS06170	COG0670	Belongs to the BI1 family
DIC78_RS06175	COG5583	Uncharacterized small protein (DUF2292)
DIC78_RS06180	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS06190	COG0346	lactoylglutathione lyase activity
DIC78_RS06195	COG2329	Antibiotic biosynthesis monooxygenase
DIC78_RS06200	COG2323	membrane
DIC78_RS06205	COG1486	melibiose metabolic process
DIC78_RS06210	COG0395	ABC-type sugar transport system, permease component
DIC78_RS06215	COG4209	transmembrane transport
DIC78_RS06220	COG1653	transport
DIC78_RS06230	COG1874	Beta-galactosidase
DIC78_RS06235	COG2755	lipolytic protein G-D-S-L family
DIC78_RS06240	COG0667	Aldo Keto reductase
DIC78_RS06245	COG3401	FG-GAP repeat protein
DIC78_RS06250	COG3401	FG-GAP repeat protein
DIC78_RS06255	COG5578	integral membrane protein
DIC78_RS06265	COG2755	lipolytic protein G-D-S-L family
DIC78_RS06270	COG2207	Transcriptional regulator
DIC78_RS06275	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DIC78_RS06280	COG0395	ABC-type sugar transport system, permease component
DIC78_RS06285	COG1175	transmembrane transport
DIC78_RS06290	COG1653	transport
DIC78_RS06295	COG4753	response regulator
DIC78_RS06295	COG2207	Transcriptional regulator
DIC78_RS06300	COG2972	Histidine kinase
DIC78_RS06305	COG5578	integral membrane protein
DIC78_RS06315	COG0454	-acetyltransferase
DIC78_RS06320	COG3546	catalase activity
DIC78_RS06335	COG1309	transcriptional regulator
DIC78_RS06340	COG2159	amidohydrolase
DIC78_RS06345	COG0702	epimerase
DIC78_RS06350	COG3631	Ketosteroid isomerase-related protein
DIC78_RS06355	COG1309	transcriptional regulator
DIC78_RS06365	COG0217	transcriptional regulatory protein
DIC78_RS06375	COG0457	Tetratricopeptide repeat
DIC78_RS06390	COG3391	amine dehydrogenase activity
DIC78_RS06395	COG5444	nuclease activity
DIC78_RS06435	COG0457	Tetratricopeptide repeat
DIC78_RS06450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DIC78_RS06455	COG1597	lipid kinase activity
DIC78_RS06460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DIC78_RS06465	COG1309	transcriptional regulator
DIC78_RS06470	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIC78_RS06475	COG0154	amidase activity
DIC78_RS06480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DIC78_RS06485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIC78_RS06490	COG1285	pathogenesis
DIC78_RS06495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DIC78_RS06500	COG4851	CamS sex pheromone cAM373 precursor
DIC78_RS06505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DIC78_RS06510	COG0210	DNA helicase
DIC78_RS06515	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DIC78_RS06520	COG0069	glutamate synthase activity
DIC78_RS06525	COG4496	protein, YerC YecD
DIC78_RS06530	COG1470	cell adhesion involved in biofilm formation
DIC78_RS06535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DIC78_RS06545	COG0531	amino acid
DIC78_RS06550	COG1522	sequence-specific DNA binding
DIC78_RS06555	COG0151	Belongs to the GarS family
DIC78_RS06560	COG0138	bifunctional purine biosynthesis protein purh
DIC78_RS06565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DIC78_RS06570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DIC78_RS06575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DIC78_RS06580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIC78_RS06585	COG0047	phosphoribosylformylglycinamidine synthase activity
DIC78_RS06590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DIC78_RS06595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DIC78_RS06600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DIC78_RS06605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DIC78_RS06610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DIC78_RS06620	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DIC78_RS06630	COG3064	Membrane
DIC78_RS06640	COG2252	PERMEase
DIC78_RS06660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DIC78_RS06660	COG0519	Catalyzes the synthesis of GMP from XMP
DIC78_RS06665	COG1305	Transglutaminase-like
DIC78_RS06670	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DIC78_RS06675	COG0714	Associated with various cellular activities
DIC78_RS06680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DIC78_RS06690	COG1113	amino acid transport
DIC78_RS06695	COG2132	Multicopper oxidase
DIC78_RS06705	COG2267	carboxylic ester hydrolase activity
DIC78_RS06715	COG0823	Involved in the tonB-independent uptake of proteins
DIC78_RS06720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DIC78_RS06725	COG1063	alcohol dehydrogenase
DIC78_RS06730	COG2814	Major facilitator Superfamily
DIC78_RS06740	COG4260	virion core protein, lumpy skin disease virus
DIC78_RS06745	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DIC78_RS06750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DIC78_RS06755	COG1842	Phage shock protein A
DIC78_RS06760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIC78_RS06765	COG2211	Major facilitator Superfamily
DIC78_RS06770	COG1063	alcohol dehydrogenase
DIC78_RS06775	COG0457	Tetratricopeptide repeat
DIC78_RS06780	COG1073	alpha beta
DIC78_RS06795	COG1266	CAAX protease self-immunity
DIC78_RS06805	COG0805	protein transport
DIC78_RS06810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIC78_RS06815	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DIC78_RS06820	COG0315	cyclic pyranopterin monophosphate synthase activity
DIC78_RS06825	COG0488	(ABC) transporter
DIC78_RS06830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DIC78_RS06835	COG0456	acetyltransferase
DIC78_RS06840	COG1214	PFAM Peptidase M22, glycoprotease
DIC78_RS06845	COG0802	atpase or kinase
DIC78_RS06850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DIC78_RS06895	COG4124	Belongs to the glycosyl hydrolase 26 family
DIC78_RS06900	COG1482	cell wall glycoprotein biosynthetic process
DIC78_RS06905	COG1940	carbohydrate kinase activity
DIC78_RS06910	COG2188	Transcriptional regulator
DIC78_RS06915	COG2723	6-phospho-beta-galactosidase activity
DIC78_RS06920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DIC78_RS06925	COG1447	Phosphotransferase system cellobiose-specific component IIA
DIC78_RS06930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DIC78_RS06935	COG2814	Major facilitator Superfamily
DIC78_RS06940	COG1388	LysM domain
DIC78_RS06945	COG1078	dGTPase activity
DIC78_RS06950	COG1785	Belongs to the alkaline phosphatase family
DIC78_RS06965	COG1819	glycosyl
DIC78_RS06970	COG3858	chitin binding
DIC78_RS06970	COG1388	LysM domain
DIC78_RS06975	COG1802	Transcriptional regulator
DIC78_RS06980	COG0730	response to heat
DIC78_RS06985	COG2814	Major facilitator Superfamily
DIC78_RS07000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DIC78_RS07005	COG1396	sequence-specific DNA binding
DIC78_RS07010	COG1846	Transcriptional regulator
DIC78_RS07015	COG0778	Nitroreductase
DIC78_RS07025	COG2409	Drug exporters of the RND superfamily
DIC78_RS07025	COG1033	growth of symbiont in host cell
DIC78_RS07030	COG1846	Transcriptional regulator
DIC78_RS07035	COG2318	DinB family
DIC78_RS07040	COG1113	amino acid transport
DIC78_RS07045	COG0488	(ABC) transporter
DIC78_RS07050	COG1082	Xylose isomerase domain protein TIM barrel
DIC78_RS07055	COG2814	Major facilitator Superfamily
DIC78_RS07060	COG1609	Transcriptional regulator
DIC78_RS07065	COG0673	inositol 2-dehydrogenase activity
DIC78_RS07075	COG0456	acetyltransferase
DIC78_RS07085	COG1309	transcriptional regulator
DIC78_RS07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS07095	COG2259	Doxx family
DIC78_RS07100	COG0346	lactoylglutathione lyase activity
DIC78_RS07105	COG0778	Nitroreductase
DIC78_RS07120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS07125	COG0596	Alpha beta hydrolase
DIC78_RS07130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS07135	COG0697	spore germination
DIC78_RS07140	COG2030	dehydratase
DIC78_RS07145	COG1482	cell wall glycoprotein biosynthetic process
DIC78_RS07150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DIC78_RS07150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DIC78_RS07150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS07155	COG3711	transcriptional antiterminator
DIC78_RS07155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS07165	COG0702	epimerase
DIC78_RS07170	COG0789	Transcriptional regulator
DIC78_RS07170	COG4978	Transcriptional regulator
DIC78_RS07175	COG0456	acetyltransferase
DIC78_RS07185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS07195	COG3764	Sortase (surface protein transpeptidase)
DIC78_RS07205	COG0346	lactoylglutathione lyase activity
DIC78_RS07210	COG0640	Transcriptional regulator
DIC78_RS07215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS07220	COG0697	spore germination
DIC78_RS07235	COG4978	Transcriptional regulator
DIC78_RS07235	COG0789	Transcriptional regulator
DIC78_RS07240	COG0697	spore germination
DIC78_RS07250	COG2808	Putative FMN-binding domain
DIC78_RS07255	COG0456	acetyltransferase
DIC78_RS07260	COG1846	Transcriptional regulator
DIC78_RS07265	COG2364	Membrane
DIC78_RS07280	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
DIC78_RS07305	COG0346	lactoylglutathione lyase activity
DIC78_RS07310	COG2315	Protein conserved in bacteria
DIC78_RS07315	COG1329	Transcriptional regulator
DIC78_RS07320	COG1278	Cold shock
DIC78_RS07325	COG1278	Cold shock
DIC78_RS07330	COG3239	Fatty acid desaturase
DIC78_RS07340	COG0457	Tetratricopeptide repeat
DIC78_RS07345	COG5444	nuclease activity
DIC78_RS07380	COG0791	NLP P60 protein
DIC78_RS07380	COG0741	lytic transglycosylase activity
DIC78_RS07385	COG5644	endopeptidase inhibitor activity
DIC78_RS07395	COG0433	COG0433 Predicted ATPase
DIC78_RS07435	COG2946	Replication initiation factor
DIC78_RS07440	COG1674	ftsk spoiiie
DIC78_RS07470	COG1396	sequence-specific DNA binding
DIC78_RS07475	COG2856	Zn peptidase
DIC78_RS07480	COG0582	viral genome integration into host DNA
DIC78_RS07520	COG3091	SprT-like family
DIC78_RS07530	COG2183	response to ionizing radiation
DIC78_RS07535	COG1846	Transcriptional regulator
DIC78_RS07540	COG1673	EVE domain
DIC78_RS07550	COG2208	phosphoserine phosphatase activity
DIC78_RS07555	COG1191	sigma factor activity
DIC78_RS07560	COG2172	sigma factor antagonist activity
DIC78_RS07565	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS07570	COG2208	phosphoserine phosphatase activity
DIC78_RS07575	COG2172	sigma factor antagonist activity
DIC78_RS07580	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS07585	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS07590	COG2337	Toxic component of a toxin-antitoxin (TA) module
DIC78_RS07595	COG0864	Transcriptional regulator
DIC78_RS07600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DIC78_RS07605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DIC78_RS07610	COG0736	holo-[acyl-carrier-protein] synthase activity
DIC78_RS07615	COG0705	Rhomboid family
DIC78_RS07620	COG3428	Bacterial PH domain
DIC78_RS07625	COG3402	PFAM membrane-flanked domain
DIC78_RS07630	COG0513	Belongs to the DEAD box helicase family
DIC78_RS07635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DIC78_RS07640	COG1181	Belongs to the D-alanine--D-alanine ligase family
DIC78_RS07645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS07650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DIC78_RS07665	COG1960	acyl-CoA dehydrogenase activity
DIC78_RS07675	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DIC78_RS07680	COG1131	(ABC) transporter
DIC78_RS07685	COG1301	dicarboxylic acid transport
DIC78_RS07690	COG0628	permease
DIC78_RS07695	COG1301	dicarboxylic acid transport
DIC78_RS07700	COG4565	transcriptional regulatory protein
DIC78_RS07705	COG3290	protein histidine kinase activity
DIC78_RS07710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DIC78_RS07715	COG3546	catalase activity
DIC78_RS07730	COG0662	Cupin 2, conserved barrel domain protein
DIC78_RS07735	COG3729	General stress protein
DIC78_RS07740	COG2217	Heavy metal translocating P-type atpase
DIC78_RS07745	COG4876	unkown
DIC78_RS07750	COG2261	transglycosylase associated protein
DIC78_RS07755	COG1914	H( )-stimulated, divalent metal cation uptake system
DIC78_RS07765	COG0028	Belongs to the TPP enzyme family
DIC78_RS07770	COG0494	nUDIX hydrolase
DIC78_RS07775	COG0531	amino acid
DIC78_RS07785	COG1215	transferase activity, transferring glycosyl groups
DIC78_RS07790	COG5298	Protein conserved in bacteria
DIC78_RS07795	COG3706	GGDEF domain
DIC78_RS07800	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DIC78_RS07805	COG0551	DNA topoisomerase type I activity
DIC78_RS07805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DIC78_RS07810	COG1522	sequence-specific DNA binding
DIC78_RS07815	COG2814	Major facilitator Superfamily
DIC78_RS07820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIC78_RS07830	COG3871	stress protein (general stress protein 26)
DIC78_RS07835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS07840	COG1917	Cupin 2, conserved barrel domain protein
DIC78_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS07850	COG2226	methyltransferase
DIC78_RS07855	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS07860	COG3711	transcriptional antiterminator
DIC78_RS07865	COG4989	oxidoreductase activity
DIC78_RS07870	COG0768	penicillin binding
DIC78_RS07875	COG2329	Antibiotic biosynthesis monooxygenase
DIC78_RS07885	COG2755	lipolytic protein G-D-S-L family
DIC78_RS07890	COG1414	Transcriptional regulator
DIC78_RS07895	COG1984	allophanate hydrolase subunit 2
DIC78_RS07900	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DIC78_RS07905	COG4336	lyase activity
DIC78_RS07910	COG1914	H( )-stimulated, divalent metal cation uptake system
DIC78_RS07915	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DIC78_RS07920	COG0561	phosphatase activity
DIC78_RS07930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DIC78_RS07935	COG0681	Belongs to the peptidase S26 family
DIC78_RS07940	COG0473	3-isopropylmalate dehydrogenase activity
DIC78_RS07945	COG0246	Mannitol dehydrogenase
DIC78_RS07950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS07955	COG2213	PTS system mannitol-specific
DIC78_RS07965	COG1349	DNA-binding transcription factor activity
DIC78_RS07970	COG1276	copper resistance
DIC78_RS07970	COG2372	response to copper ion
DIC78_RS07975	COG4549	nuclear export factor GLE1
DIC78_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS07985	COG4975	Glucose uptake
DIC78_RS07990	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS07995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DIC78_RS08000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS08005	COG0640	Transcriptional regulator
DIC78_RS08010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DIC78_RS08015	COG0778	Nitroreductase
DIC78_RS08020	COG1309	transcriptional regulator
DIC78_RS08025	COG2814	Major facilitator Superfamily
DIC78_RS08030	COG4607	ABC-type enterochelin transport system periplasmic component
DIC78_RS08035	COG4604	ABC transporter, ATP-binding protein
DIC78_RS08040	COG4605	iron ion homeostasis
DIC78_RS08045	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS08050	COG0527	aspartate kinase activity
DIC78_RS08070	COG0457	Tetratricopeptide repeat
DIC78_RS08075	COG3850	Histidine kinase
DIC78_RS08075	COG5002	protein histidine kinase activity
DIC78_RS08080	COG0745	RESPONSE REGULATOR receiver
DIC78_RS08085	COG0577	efflux transmembrane transporter activity
DIC78_RS08090	COG1136	(ABC) transporter
DIC78_RS08095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DIC78_RS08105	COG0697	spore germination
DIC78_RS08115	COG5434	Belongs to the glycosyl hydrolase 28 family
DIC78_RS08120	COG3104	oligopeptide transport
DIC78_RS08125	COG0596	Alpha beta hydrolase
DIC78_RS08140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DIC78_RS08145	COG0163	prenyltransferase activity
DIC78_RS08150	COG0583	DNA-binding transcription factor activity
DIC78_RS08155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS08160	COG0765	amino acid transport
DIC78_RS08165	COG1126	abc transporter atp-binding protein
DIC78_RS08170	COG2364	Membrane
DIC78_RS08180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS08190	COG0697	spore germination
DIC78_RS08200	COG2814	Major facilitator Superfamily
DIC78_RS08205	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DIC78_RS08210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS08215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS08220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS08225	COG1733	regulation of RNA biosynthetic process
DIC78_RS08230	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DIC78_RS08235	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DIC78_RS08240	COG0840	transmembrane signaling receptor activity
DIC78_RS08240	COG3290	protein histidine kinase activity
DIC78_RS08245	COG3209	COG3209 Rhs family protein
DIC78_RS08255	COG2723	6-phospho-beta-galactosidase activity
DIC78_RS08260	COG3842	ATPase activity
DIC78_RS08275	COG1063	alcohol dehydrogenase
DIC78_RS08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS08285	COG0765	amino acid transport
DIC78_RS08290	COG0523	cobalamin synthesis protein
DIC78_RS08300	COG1376	ErfK ybiS ycfS ynhG family protein
DIC78_RS08305	COG1469	GTP cyclohydrolase I activity
DIC78_RS08310	COG2223	nitrite transmembrane transporter activity
DIC78_RS08315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIC78_RS08320	COG0243	molybdopterin cofactor binding
DIC78_RS08325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIC78_RS08330	COG2146	nitrite reductase [NAD(P)H] activity
DIC78_RS08335	COG1587	Uroporphyrinogen-III synthase
DIC78_RS08335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DIC78_RS08340	COG0492	ferredoxin-NADP+ reductase activity
DIC78_RS08345	COG0701	Predicted permease
DIC78_RS08350	COG3689	TIGRFAM TIGR03943 family protein
DIC78_RS08355	COG2508	Transcriptional regulator
DIC78_RS08360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIC78_RS08365	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS08370	COG0506	proline dehydrogenase activity
DIC78_RS08375	COG3541	Predicted nucleotidyltransferase
DIC78_RS08380	COG3458	cephalosporin-C deacetylase activity
DIC78_RS08385	COG0583	DNA-binding transcription factor activity
DIC78_RS08390	COG2226	methyltransferase
DIC78_RS08395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DIC78_RS08405	COG1660	Displays ATPase and GTPase activities
DIC78_RS08410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DIC78_RS08415	COG3665	Urea carboxylase-associated protein
DIC78_RS08420	COG1113	amino acid transport
DIC78_RS08425	COG3403	YqcI/YcgG family
DIC78_RS08430	COG1280	lysine exporter protein (LysE YggA)
DIC78_RS08435	COG1846	Transcriptional regulator
DIC78_RS08440	COG2814	Major facilitator Superfamily
DIC78_RS08445	COG1620	l-lactate permease
DIC78_RS08450	COG0039	L-malate dehydrogenase activity
DIC78_RS08455	COG0366	Alpha amylase catalytic
DIC78_RS08465	COG1288	antiporter activity
DIC78_RS08470	COG1473	amidohydrolase
DIC78_RS08475	COG2113	Glycine betaine
DIC78_RS08480	COG4176	ABC-type proline glycine betaine transport system permease component
DIC78_RS08485	COG4175	Glycine betaine
DIC78_RS08485	COG0517	IMP dehydrogenase activity
DIC78_RS08490	COG0640	Transcriptional regulator
DIC78_RS08495	COG2814	Major facilitator Superfamily
DIC78_RS08500	COG0477	Major facilitator Superfamily
DIC78_RS08505	COG3853	Toxic anion resistance protein (TelA)
DIC78_RS08520	COG1358	cellular component organization or biogenesis
DIC78_RS08535	COG0861	Integral membrane protein TerC family
DIC78_RS08540	COG2310	stress, protein
DIC78_RS08545	COG2310	stress, protein
DIC78_RS08550	COG2310	stress, protein
DIC78_RS08555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS08560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIC78_RS08565	COG1121	(ABC) transporter
DIC78_RS08570	COG0803	Belongs to the bacterial solute-binding protein 9 family
DIC78_RS08575	COG0366	Alpha amylase catalytic
DIC78_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS08585	COG0457	Tetratricopeptide repeat
DIC78_RS08590	COG1876	peptidase activity
DIC78_RS08595	COG1595	DNA-templated transcription, initiation
DIC78_RS08600	COG1595	DNA-templated transcription, initiation
DIC78_RS08615	COG0667	Aldo Keto reductase
DIC78_RS08620	COG1668	transmembrane transport
DIC78_RS08625	COG4555	ABC transporter
DIC78_RS08630	COG3279	Response regulator of the LytR AlgR family
DIC78_RS08635	COG3290	protein histidine kinase activity
DIC78_RS08640	COG3012	SEC-C Motif Domain Protein
DIC78_RS08640	COG1405	negative regulation of cell septum assembly
DIC78_RS08645	COG1714	RDD family
DIC78_RS08650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DIC78_RS08655	COG0252	asparaginase activity
DIC78_RS08660	COG1309	transcriptional regulator
DIC78_RS08665	COG0477	Major facilitator Superfamily
DIC78_RS08670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DIC78_RS08675	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DIC78_RS08680	COG0805	protein transport
DIC78_RS08685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DIC78_RS08690	COG3540	Alkaline phosphatase
DIC78_RS08700	COG2304	oxidoreductase activity
DIC78_RS08705	COG3773	Cell wall hydrolase
DIC78_RS08725	COG1131	(ABC) transporter
DIC78_RS08730	COG2205	protein histidine kinase activity
DIC78_RS08735	COG0745	RESPONSE REGULATOR receiver
DIC78_RS08745	COG3173	Aminoglycoside phosphotransferase
DIC78_RS08750	COG2721	sulfolactate sulfo-lyase activity
DIC78_RS08755	COG2186	Transcriptional regulator
DIC78_RS08760	COG4948	Mandelate Racemase Muconate Lactonizing
DIC78_RS08765	COG2271	Major facilitator Superfamily
DIC78_RS08770	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS08775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DIC78_RS08785	COG0784	Response regulator, receiver
DIC78_RS08790	COG4191	Histidine kinase
DIC78_RS08795	COG2066	Belongs to the glutaminase family
DIC78_RS08800	COG1115	amino acid carrier protein
DIC78_RS08805	COG2040	homocysteine
DIC78_RS08810	COG0833	amino acid
DIC78_RS08815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIC78_RS08825	COG2188	Transcriptional regulator
DIC78_RS08830	COG0363	glucosamine-6-phosphate deaminase activity
DIC78_RS08835	COG2190	(PTS) system
DIC78_RS08835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS08835	COG1263	PTS System
DIC78_RS08840	COG1301	dicarboxylic acid transport
DIC78_RS08845	COG1054	Belongs to the UPF0176 family
DIC78_RS08850	COG2207	Transcriptional regulator
DIC78_RS08860	COG2312	Erythromycin esterase
DIC78_RS08870	COG0688	phosphatidylethanolamine metabolic process
DIC78_RS08875	COG0586	Pfam SNARE associated Golgi protein
DIC78_RS08880	COG1183	phosphatidylcholine synthase activity
DIC78_RS08885	COG0596	Alpha beta hydrolase
DIC78_RS08895	COG3591	Belongs to the peptidase S1B family
DIC78_RS08900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DIC78_RS08905	COG0371	Dehydrogenase
DIC78_RS08910	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS08920	COG2271	Major facilitator Superfamily
DIC78_RS08925	COG1846	Transcriptional regulator
DIC78_RS08925	COG0456	acetyltransferase
DIC78_RS08940	COG2271	Major facilitator Superfamily
DIC78_RS08945	COG0584	glycerophosphoryl diester phosphodiesterase
DIC78_RS08950	COG0531	amino acid
DIC78_RS08960	COG2124	cytochrome p450
DIC78_RS08965	COG2602	Beta-lactamase
DIC78_RS08980	COG1113	amino acid transport
DIC78_RS08995	COG0515	serine threonine protein kinase
DIC78_RS09005	COG0642	Histidine kinase
DIC78_RS09010	COG0745	RESPONSE REGULATOR receiver
DIC78_RS09015	COG0596	Alpha beta hydrolase
DIC78_RS09025	COG1413	lyase activity
DIC78_RS09035	COG2814	Major facilitator Superfamily
DIC78_RS09040	COG0640	Transcriptional regulator
DIC78_RS09045	COG5609	conserved protein (DUF2294)
DIC78_RS09055	COG0288	reversible hydration of carbon dioxide
DIC78_RS09060	COG3002	Belongs to the UPF0753 family
DIC78_RS09065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIC78_RS09080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DIC78_RS09085	COG4856	YbbR-like protein
DIC78_RS09090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DIC78_RS09095	COG5662	AntiSigma factor
DIC78_RS09100	COG1595	DNA-templated transcription, initiation
DIC78_RS09130	COG1683	Conserved Protein
DIC78_RS09135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS09140	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DIC78_RS09145	COG1737	Transcriptional regulator
DIC78_RS09150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS09150	COG1263	PTS System
DIC78_RS09155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIC78_RS09160	COG1472	Belongs to the glycosyl hydrolase 3 family
DIC78_RS09165	COG3876	Protein conserved in bacteria
DIC78_RS09170	COG2207	Transcriptional regulator
DIC78_RS09170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIC78_RS09175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIC78_RS09180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS09185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS09190	COG2819	hydrolase of the alpha beta superfamily
DIC78_RS09195	COG0385	Bile acid
DIC78_RS09200	COG0659	secondary active sulfate transmembrane transporter activity
DIC78_RS09285	COG0726	polysaccharide deacetylase
DIC78_RS09290	COG2194	sulfuric ester hydrolase activity
DIC78_RS09300	COG0489	protein tyrosine kinase activity
DIC78_RS09305	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS09315	COG2226	methyltransferase
DIC78_RS09325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DIC78_RS09330	COG0101	tRNA pseudouridine synthase activity
DIC78_RS09335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DIC78_RS09340	COG1122	ATPase activity
DIC78_RS09345	COG1122	ATPase activity
DIC78_RS09350	COG0203	ribosomal protein L17
DIC78_RS09355	COG0202	RNA polymerase activity
DIC78_RS09360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DIC78_RS09370	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DIC78_RS09385	COG0024	Methionine aminopeptidase
DIC78_RS09390	COG0563	adenylate kinase activity
DIC78_RS09395	COG0201	protein transport
DIC78_RS09400	COG0200	Binds to the 23S rRNA
DIC78_RS09415	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DIC78_RS09420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DIC78_RS09425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DIC78_RS09435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DIC78_RS09445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DIC78_RS09450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DIC78_RS09460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DIC78_RS09480	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DIC78_RS09495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DIC78_RS09505	COG0596	Alpha beta hydrolase
DIC78_RS09510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DIC78_RS09515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DIC78_RS09520	COG0049	tRNA binding
DIC78_RS09530	COG1358	cellular component organization or biogenesis
DIC78_RS09535	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DIC78_RS09540	COG0085	RNA polymerase activity
DIC78_RS09545	COG2813	Specifically methylates the guanine in position
DIC78_RS09560	COG0081	regulation of translation
DIC78_RS09570	COG0250	Participates in transcription elongation, termination and antitermination
DIC78_RS09575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DIC78_RS09585	COG1595	DNA-templated transcription, initiation
DIC78_RS09590	COG3688	RNA-binding protein containing a PIN domain
DIC78_RS09595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIC78_RS09600	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DIC78_RS09605	COG0215	cysteine-tRNA ligase activity
DIC78_RS09610	COG1045	serine acetyltransferase
DIC78_RS09615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DIC78_RS09620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DIC78_RS09625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DIC78_RS09630	COG4956	integral membrane protein (PIN domain superfamily)
DIC78_RS09635	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DIC78_RS09640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DIC78_RS09645	COG0542	response to heat
DIC78_RS09650	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DIC78_RS09655	COG3880	PFAM UvrB UvrC protein
DIC78_RS09660	COG4463	regulation of RNA biosynthetic process
DIC78_RS09740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DIC78_RS09745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DIC78_RS09750	COG1396	sequence-specific DNA binding
DIC78_RS09755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DIC78_RS09760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DIC78_RS09765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DIC78_RS09770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIC78_RS09775	COG0512	Glutamine amidotransferase of anthranilate synthase
DIC78_RS09780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIC78_RS09785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DIC78_RS09790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DIC78_RS09795	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DIC78_RS09800	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DIC78_RS09805	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DIC78_RS09810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DIC78_RS09815	COG0037	tRNA processing
DIC78_RS09820	COG0515	serine threonine protein kinase
DIC78_RS09825	COG2304	oxidoreductase activity
DIC78_RS09830	COG2208	phosphoserine phosphatase activity
DIC78_RS09845	COG1098	S1 RNA binding domain
DIC78_RS09850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DIC78_RS09865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DIC78_RS09870	COG3956	TIGRFAM MazG family protein
DIC78_RS09875	COG2244	polysaccharide biosynthetic process
DIC78_RS09880	COG2002	toxin-antitoxin pair type II binding
DIC78_RS09885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DIC78_RS09895	COG0193	aminoacyl-tRNA hydrolase activity
DIC78_RS09900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DIC78_RS09905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DIC78_RS09910	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DIC78_RS09915	COG2088	sporulation resulting in formation of a cellular spore
DIC78_RS09920	COG0251	oxidation-reduction process
DIC78_RS09925	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIC78_RS09930	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DIC78_RS09940	COG4466	Protein conserved in bacteria
DIC78_RS09950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DIC78_RS09955	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DIC78_RS09960	COG3584	3D domain protein
DIC78_RS09960	COG3583	domain protein
DIC78_RS09965	COG0084	hydrolase, TatD family'
DIC78_RS09970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIC78_RS09970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIC78_RS09975	COG2002	toxin-antitoxin pair type II binding
DIC78_RS09980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DIC78_RS09985	COG2827	Endonuclease containing a URI domain
DIC78_RS09990	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DIC78_RS10000	COG1774	PSP1 C-terminal conserved region
DIC78_RS10005	COG0470	DNA polymerase III
DIC78_RS10010	COG1728	Protein conserved in bacteria
DIC78_RS10015	COG3870	Protein conserved in bacteria
DIC78_RS10020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DIC78_RS10025	COG1982	Orn Lys Arg decarboxylase major
DIC78_RS10030	COG3853	Toxic anion resistance protein (TelA)
DIC78_RS10035	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DIC78_RS10080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DIC78_RS10085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DIC78_RS10090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DIC78_RS10100	COG0590	tRNA wobble adenosine to inosine editing
DIC78_RS10105	COG1335	isochorismatase
DIC78_RS10110	COG1388	LysM domain
DIC78_RS10110	COG3858	chitin binding
DIC78_RS10115	COG1428	Deoxynucleoside kinase
DIC78_RS10120	COG1428	Deoxynucleoside kinase
DIC78_RS10130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DIC78_RS10135	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DIC78_RS10145	COG1686	Belongs to the peptidase S11 family
DIC78_RS10150	COG0517	IMP dehydrogenase activity
DIC78_RS10150	COG0516	GMP reductase activity
DIC78_RS10185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DIC78_RS10195	COG0187	DNA topoisomerase II activity
DIC78_RS10205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DIC78_RS10210	COG2501	S4 domain
DIC78_RS10215	COG0592	DNA-directed DNA polymerase activity
DIC78_RS10220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DIC78_RS10230	COG0594	ribonuclease P activity
DIC78_RS10235	COG0706	membrane insertase activity
DIC78_RS10240	COG1847	R3H domain protein
DIC78_RS10245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DIC78_RS10250	COG0445	tRNA wobble uridine modification
DIC78_RS10255	COG0357	Ribosomal RNA small subunit methyltransferase G
DIC78_RS10260	COG1475	DNA binding
DIC78_RS10270	COG1192	Involved in chromosome partitioning
DIC78_RS10275	COG1475	DNA binding
DIC78_RS10285	COG3949	Membrane
DIC78_RS10290	COG4481	Protein conserved in bacteria
DIC78_RS10295	COG0243	molybdopterin cofactor binding
DIC78_RS10300	COG0012	GTP binding
DIC78_RS10305	COG0360	Binds together with S18 to 16S ribosomal RNA
DIC78_RS10310	COG0629	single-stranded DNA binding
DIC78_RS10320	COG0708	Exodeoxyribonuclease III
DIC78_RS10325	COG1609	Transcriptional regulator
DIC78_RS10330	COG0346	lactoylglutathione lyase activity
DIC78_RS10335	COG0110	maltose O-acetyltransferase activity
DIC78_RS10340	COG2814	Major facilitator Superfamily
DIC78_RS10340	COG0477	Major facilitator Superfamily
DIC78_RS10345	COG1266	CAAX protease self-immunity
DIC78_RS10350	COG1331	Highly conserved protein containing a thioredoxin domain
DIC78_RS10385	COG2856	Zn peptidase
DIC78_RS10390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DIC78_RS10410	COG1331	Highly conserved protein containing a thioredoxin domain
DIC78_RS10415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DIC78_RS10435	COG2207	Transcriptional regulator
DIC78_RS10435	COG3708	Transcriptional regulator
DIC78_RS10440	COG1811	Na channel or pump
DIC78_RS10445	COG0789	Transcriptional regulator
DIC78_RS10445	COG4978	Transcriptional regulator
DIC78_RS10460	COG1063	alcohol dehydrogenase
DIC78_RS10470	COG1309	transcriptional regulator
DIC78_RS10475	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIC78_RS10475	COG0596	Alpha beta hydrolase
DIC78_RS10480	COG1902	pentaerythritol trinitrate reductase activity
DIC78_RS10485	COG0300	oxidoreductase activity
DIC78_RS10520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIC78_RS10525	COG0640	Transcriptional regulator
DIC78_RS10535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS10550	COG0583	DNA-binding transcription factor activity
DIC78_RS10560	COG2153	protein acetylation
DIC78_RS10565	COG0583	DNA-binding transcription factor activity
DIC78_RS10570	COG2814	Major facilitator Superfamily
DIC78_RS10575	COG1357	PFAM Pentapeptide repeats (8 copies)
DIC78_RS10580	COG4319	ketosteroid isomerase
DIC78_RS10590	COG4978	Transcriptional regulator
DIC78_RS10590	COG0789	Transcriptional regulator
DIC78_RS10595	COG2271	Major facilitator Superfamily
DIC78_RS10605	COG1227	inorganic diphosphatase activity
DIC78_RS10610	COG1733	regulation of RNA biosynthetic process
DIC78_RS10615	COG5577	PFAM Coat F domain
DIC78_RS10625	COG4241	membrane
DIC78_RS10630	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DIC78_RS10635	COG0359	binds to the 23S rRNA
DIC78_RS10640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DIC78_RS10645	COG2807	transmembrane transport
DIC78_RS10650	COG3093	addiction module antidote protein HigA
DIC78_RS10665	COG0305	Participates in initiation and elongation during chromosome replication
DIC78_RS10670	COG0346	lactoylglutathione lyase activity
DIC78_RS10700	COG0745	RESPONSE REGULATOR receiver
DIC78_RS10705	COG5002	protein histidine kinase activity
DIC78_RS10710	COG4863	YycH protein
DIC78_RS10715	COG4853	Protein conserved in bacteria
DIC78_RS10720	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DIC78_RS10725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIC78_RS10735	COG3829	transcription factor binding
DIC78_RS10740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DIC78_RS10745	COG0833	amino acid
DIC78_RS10750	COG0010	Belongs to the arginase family
DIC78_RS10760	COG0457	Tetratricopeptide repeat
DIC78_RS10765	COG0456	acetyltransferase
DIC78_RS10770	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DIC78_RS10785	COG1063	alcohol dehydrogenase
DIC78_RS10800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DIC78_RS10820	COG0210	DNA helicase
DIC78_RS10825	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DIC78_RS10835	COG2188	Transcriptional regulator
DIC78_RS10840	COG1263	PTS System
DIC78_RS10840	COG2190	(PTS) system
DIC78_RS10840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS10845	COG2723	6-phospho-beta-galactosidase activity
DIC78_RS10855	COG3634	alkyl hydroperoxide reductase activity
DIC78_RS10860	COG0450	alkyl hydroperoxide reductase
DIC78_RS10865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DIC78_RS10870	COG2610	gluconate transmembrane transporter activity
DIC78_RS10875	COG1070	Carbohydrate kinase
DIC78_RS10880	COG1802	Transcriptional regulator
DIC78_RS10885	COG1929	Belongs to the glycerate kinase type-1 family
DIC78_RS10890	COG5039	Polysaccharide pyruvyl transferase
DIC78_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS10920	COG1309	transcriptional regulator
DIC78_RS10925	COG1917	Cupin 2, conserved barrel domain protein
DIC78_RS10930	COG2311	Membrane
DIC78_RS10935	COG1714	RDD family
DIC78_RS10940	COG0789	Transcriptional regulator
DIC78_RS10950	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS10955	COG1309	transcriptional regulator
DIC78_RS10960	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS10970	COG0326	Molecular chaperone. Has ATPase activity
DIC78_RS10975	COG2814	Major facilitator Superfamily
DIC78_RS11000	COG0667	Aldo Keto reductase
DIC78_RS11005	COG1349	DNA-binding transcription factor activity
DIC78_RS11010	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS11020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIC78_RS11025	COG3962	Belongs to the TPP enzyme family
DIC78_RS11030	COG1082	Xylose isomerase domain protein TIM barrel
DIC78_RS11035	COG2814	Major facilitator Superfamily
DIC78_RS11040	COG0673	inositol 2-dehydrogenase activity
DIC78_RS11045	COG1082	Xylose isomerase domain protein TIM barrel
DIC78_RS11055	COG0191	fructose-bisphosphate aldolase activity
DIC78_RS11060	COG0745	RESPONSE REGULATOR receiver
DIC78_RS11065	COG2205	protein histidine kinase activity
DIC78_RS11070	COG1136	(ABC) transporter
DIC78_RS11075	COG0577	efflux transmembrane transporter activity
DIC78_RS11080	COG5294	Protein conserved in bacteria
DIC78_RS11085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIC78_RS11115	COG0561	phosphatase activity
DIC78_RS11120	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DIC78_RS11130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS11135	COG0456	acetyltransferase
DIC78_RS11140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS11145	COG0765	amino acid transport
DIC78_RS11150	COG1126	abc transporter atp-binding protein
DIC78_RS11155	COG1473	amidohydrolase
DIC78_RS11160	COG2079	MmgE PrpD family protein
DIC78_RS11165	COG3192	ethanolamine utilization protein
DIC78_RS11175	COG2390	Transcriptional regulator
DIC78_RS11180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DIC78_RS11185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DIC78_RS11190	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DIC78_RS11195	COG0833	amino acid
DIC78_RS11200	COG0010	Belongs to the arginase family
DIC78_RS11205	COG1228	amidohydrolase
DIC78_RS11210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DIC78_RS11215	COG2986	histidine ammonia-lyase
DIC78_RS11230	COG3507	Belongs to the glycosyl hydrolase 43 family
DIC78_RS11275	COG1263	PTS System
DIC78_RS11275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS11275	COG2190	(PTS) system
DIC78_RS11280	COG2723	6-phospho-beta-galactosidase activity
DIC78_RS11285	COG0589	response to stress
DIC78_RS11290	COG0697	spore germination
DIC78_RS11355	COG3401	FG-GAP repeat protein
DIC78_RS11355	COG2755	lipolytic protein G-D-S-L family
DIC78_RS11360	COG0513	Belongs to the DEAD box helicase family
DIC78_RS11365	COG2270	Major facilitator Superfamily
DIC78_RS11375	COG3711	transcriptional antiterminator
DIC78_RS11380	COG1263	PTS System
DIC78_RS11380	COG2190	(PTS) system
DIC78_RS11380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS11385	COG2723	6-phospho-beta-galactosidase activity
DIC78_RS11395	COG2851	Citrate transporter
DIC78_RS11400	COG0693	protein deglycase activity
DIC78_RS11400	COG0753	catalase activity
DIC78_RS11415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DIC78_RS11420	COG0500	methyltransferase
DIC78_RS11425	COG2610	gluconate transmembrane transporter activity
DIC78_RS11430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIC78_RS11435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DIC78_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS11445	COG3829	transcription factor binding
DIC78_RS11445	COG3290	protein histidine kinase activity
DIC78_RS11450	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DIC78_RS11455	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DIC78_RS11465	COG2195	Cleaves the N-terminal amino acid of tripeptides
DIC78_RS11480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DIC78_RS11490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS11495	COG2508	Transcriptional regulator
DIC78_RS11500	COG3842	ATPase activity
DIC78_RS11510	COG0726	polysaccharide deacetylase
DIC78_RS11525	COG3493	citrate carrier protein
DIC78_RS11530	COG1271	oxidase subunit
DIC78_RS11535	COG1294	oxidase, subunit
DIC78_RS11540	COG4988	ABC transporter
DIC78_RS11545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DIC78_RS11550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DIC78_RS11555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DIC78_RS11560	COG1595	DNA-templated transcription, initiation
DIC78_RS11580	COG1131	(ABC) transporter
DIC78_RS11585	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DIC78_RS11590	COG2814	Major facilitator Superfamily
DIC78_RS11595	COG0753	catalase activity
DIC78_RS11600	COG2094	Belongs to the DNA glycosylase MPG family
DIC78_RS11610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS11610	COG3711	transcriptional antiterminator
DIC78_RS11615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DIC78_RS11620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DIC78_RS11625	COG1447	Phosphotransferase system cellobiose-specific component IIA
DIC78_RS11630	COG1486	melibiose metabolic process
DIC78_RS11635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DIC78_RS11640	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DIC78_RS11645	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DIC78_RS11650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DIC78_RS11655	COG1696	Membrane protein involved in D-alanine export
DIC78_RS11660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS11670	COG1575	Belongs to the MenA family. Type 1 subfamily
DIC78_RS11675	COG2357	RelA SpoT domain protein
DIC78_RS11680	COG2814	Major facilitator Superfamily
DIC78_RS11695	COG2234	aminopeptidase activity
DIC78_RS11700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIC78_RS11705	COG1846	Transcriptional regulator
DIC78_RS11710	COG5522	Integral membrane protein (intg_mem_TP0381)
DIC78_RS11715	COG1442	glycosyl transferase family 8
DIC78_RS11720	COG3711	transcriptional antiterminator
DIC78_RS11725	COG1263	PTS System
DIC78_RS11725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS11730	COG1404	Belongs to the peptidase S8 family
DIC78_RS11740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DIC78_RS11750	COG0346	lactoylglutathione lyase activity
DIC78_RS11755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DIC78_RS11760	COG4895	conserved protein (DUF2196)
DIC78_RS11765	COG2814	Major facilitator Superfamily
DIC78_RS11770	COG1346	cytolysis
DIC78_RS11775	COG1380	Effector of murein hydrolase LrgA
DIC78_RS11780	COG0583	DNA-binding transcription factor activity
DIC78_RS11785	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DIC78_RS11790	COG0352	thiamine-phosphate diphosphorylase activity
DIC78_RS11795	COG0672	)-iron permease
DIC78_RS11800	COG2822	iron ion transport
DIC78_RS11805	COG2837	iron assimilation
DIC78_RS11810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DIC78_RS11815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIC78_RS11820	COG3162	membrane
DIC78_RS11830	COG1309	transcriptional regulator
DIC78_RS11835	COG2246	polysaccharide biosynthetic process
DIC78_RS11840	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DIC78_RS11845	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DIC78_RS11850	COG2261	transglycosylase associated protein
DIC78_RS11855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DIC78_RS11860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DIC78_RS11880	COG0772	Belongs to the SEDS family
DIC78_RS11885	COG0778	Nitroreductase
DIC78_RS11890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS11895	COG1404	Belongs to the peptidase S8 family
DIC78_RS11905	COG3711	transcriptional antiterminator
DIC78_RS11910	COG2116	formate transmembrane transporter activity
DIC78_RS11915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS11915	COG1263	PTS System
DIC78_RS11920	COG1621	beta-fructofuranosidase activity
DIC78_RS11930	COG0351	phosphomethylpyrimidine kinase
DIC78_RS11935	COG1695	Transcriptional regulator
DIC78_RS11950	COG1216	Glycosyl transferase, family 2
DIC78_RS11955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DIC78_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS11970	COG2233	PERMEase
DIC78_RS11975	COG2363	Small membrane protein
DIC78_RS11985	COG0463	Glycosyl transferase, family 2
DIC78_RS11990	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DIC78_RS11995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIC78_RS12000	COG0456	acetyltransferase
DIC78_RS12005	COG2089	acid synthase
DIC78_RS12010	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DIC78_RS12015	COG3980	spore coat polysaccharide biosynthesis protein
DIC78_RS12020	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DIC78_RS12025	COG1088	dTDP-glucose 4,6-dehydratase activity
DIC78_RS12030	COG1091	dTDP-4-dehydrorhamnose reductase activity
DIC78_RS12035	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DIC78_RS12045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIC78_RS12050	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS12055	COG4187	Peptidase family M20/M25/M40
DIC78_RS12060	COG0833	amino acid
DIC78_RS12070	COG2814	Major facilitator Superfamily
DIC78_RS12075	COG0077	Prephenate dehydratase
DIC78_RS12080	COG1917	Cupin 2, conserved barrel domain protein
DIC78_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS12090	COG0151	Belongs to the GarS family
DIC78_RS12095	COG2814	Major facilitator Superfamily
DIC78_RS12100	COG0436	Aminotransferase
DIC78_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS12110	COG3253	May function as heme-dependent peroxidase
DIC78_RS12115	COG0280	phosphate acetyltransferase
DIC78_RS12120	COG0583	DNA-binding transcription factor activity
DIC78_RS12125	COG0095	Lipoate-protein ligase
DIC78_RS12130	COG0697	spore germination
DIC78_RS12140	COG4844	belongs to the
DIC78_RS12145	COG1078	dGTPase activity
DIC78_RS12150	COG3465	dGTPase activity
DIC78_RS12155	COG1959	2 iron, 2 sulfur cluster binding
DIC78_RS12160	COG0477	Major facilitator Superfamily
DIC78_RS12165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DIC78_RS12170	COG1846	Transcriptional regulator
DIC78_RS12175	COG1942	4-Oxalocrotonate Tautomerase
DIC78_RS12180	COG1994	Peptidase M50
DIC78_RS12195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIC78_RS12200	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DIC78_RS12205	COG0010	Belongs to the arginase family
DIC78_RS12215	COG0457	Tetratricopeptide repeat
DIC78_RS12225	COG3391	amine dehydrogenase activity
DIC78_RS12245	COG0612	Peptidase, M16
DIC78_RS12255	COG1131	(ABC) transporter
DIC78_RS12265	COG0535	radical SAM domain protein
DIC78_RS12280	COG4506	Protein conserved in bacteria
DIC78_RS12285	COG0018	arginyl-trna synthetase
DIC78_RS12290	COG2223	nitrite transmembrane transporter activity
DIC78_RS12295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DIC78_RS12305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DIC78_RS12310	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DIC78_RS12315	COG1140	nitrate reductase beta subunit
DIC78_RS12320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DIC78_RS12325	COG2181	nitrate reductase activity
DIC78_RS12335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIC78_RS12340	COG1132	(ABC) transporter
DIC78_RS12345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIC78_RS12355	COG4294	response to UV
DIC78_RS12360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIC78_RS12365	COG2181	nitrate reductase activity
DIC78_RS12365	COG0247	lactate metabolic process
DIC78_RS12370	COG1960	acyl-CoA dehydrogenase activity
DIC78_RS12375	COG3343	RNA polymerase activity
DIC78_RS12380	COG0504	CTP synthase activity
DIC78_RS12385	COG4821	SIS domain
DIC78_RS12390	COG2204	response regulator
DIC78_RS12395	COG0191	fructose-bisphosphate aldolase activity
DIC78_RS12400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DIC78_RS12405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIC78_RS12410	COG1494	fructose-1,6-bisphosphatase
DIC78_RS12420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DIC78_RS12430	COG1435	thymidine kinase activity
DIC78_RS12435	COG0281	malic enzyme
DIC78_RS12440	COG0679	Auxin Efflux Carrier
DIC78_RS12445	COG0789	Transcriptional regulator
DIC78_RS12450	COG0346	lactoylglutathione lyase activity
DIC78_RS12455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DIC78_RS12460	COG2890	protein-(glutamine-N5) methyltransferase activity
DIC78_RS12480	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DIC78_RS12485	COG0009	L-threonylcarbamoyladenylate synthase
DIC78_RS12490	COG1971	Probably functions as a manganese efflux pump
DIC78_RS12495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIC78_RS12500	COG0698	ribose 5-phosphate isomerase
DIC78_RS12505	COG4475	Protein of unknown function (DUF436)
DIC78_RS12510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DIC78_RS12515	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DIC78_RS12525	COG0356	it plays a direct role in the translocation of protons across the membrane
DIC78_RS12535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DIC78_RS12540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DIC78_RS12550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DIC78_RS12555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DIC78_RS12560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DIC78_RS12570	COG4836	Membrane
DIC78_RS12580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DIC78_RS12585	COG2385	sporulation resulting in formation of a cellular spore
DIC78_RS12590	COG2304	oxidoreductase activity
DIC78_RS12595	COG2304	oxidoreductase activity
DIC78_RS12605	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DIC78_RS12610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DIC78_RS12615	COG0457	Tetratricopeptide repeat
DIC78_RS12620	COG1994	Peptidase M50
DIC78_RS12625	COG3237	CsbD-like
DIC78_RS12655	COG0831	urea catabolic process
DIC78_RS12660	COG0832	Belongs to the urease beta subunit family
DIC78_RS12665	COG0804	urea catabolic process
DIC78_RS12670	COG1959	2 iron, 2 sulfur cluster binding
DIC78_RS12675	COG2910	NAD(P)H-binding
DIC78_RS12685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DIC78_RS12700	COG1247	-acetyltransferase
DIC78_RS12705	COG0739	heme binding
DIC78_RS12715	COG0671	phosphoesterase, PA-phosphatase related
DIC78_RS12720	COG0347	Belongs to the P(II) protein family
DIC78_RS12725	COG0004	ammonium transporteR
DIC78_RS12735	COG1335	isochorismatase
DIC78_RS12740	COG0477	Major facilitator Superfamily
DIC78_RS12745	COG1953	Uracil, thiamine, allantoin
DIC78_RS12750	COG3420	alginic acid biosynthetic process
DIC78_RS12755	COG2814	Major facilitator Superfamily
DIC78_RS12760	COG1846	Transcriptional regulator
DIC78_RS12770	COG1609	Transcriptional regulator
DIC78_RS12775	COG1077	Cell shape determining protein MreB Mrl
DIC78_RS12780	COG4786	Flagellar basal body rod
DIC78_RS12785	COG4786	Flagellar basal body rod
DIC78_RS12790	COG0457	Tetratricopeptide repeat
DIC78_RS12795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DIC78_RS12800	COG1970	mechanosensitive ion channel activity
DIC78_RS12805	COG2602	Beta-lactamase
DIC78_RS12820	COG0629	single-stranded DNA binding
DIC78_RS12825	COG1349	DNA-binding transcription factor activity
DIC78_RS12830	COG0561	phosphatase activity
DIC78_RS12835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DIC78_RS12840	COG4715	Zinc finger, swim domain protein
DIC78_RS12850	COG3944	biosynthesis protein
DIC78_RS12855	COG0489	protein tyrosine kinase activity
DIC78_RS12860	COG4464	protein tyrosine phosphatase activity
DIC78_RS12865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DIC78_RS12890	COG5444	nuclease activity
DIC78_RS12930	COG0583	DNA-binding transcription factor activity
DIC78_RS12935	COG0655	NAD(P)H dehydrogenase (quinone) activity
DIC78_RS12945	COG2059	Chromate
DIC78_RS12950	COG2059	Chromate
DIC78_RS12955	COG1522	sequence-specific DNA binding
DIC78_RS12960	COG0405	Gamma-glutamyltransferase
DIC78_RS12970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DIC78_RS12985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS12990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DIC78_RS13000	COG5337	Spore coat protein CotH
DIC78_RS13015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DIC78_RS13020	COG0583	DNA-binding transcription factor activity
DIC78_RS13025	COG0028	Belongs to the TPP enzyme family
DIC78_RS13030	COG3527	Alpha-acetolactate decarboxylase
DIC78_RS13035	COG2249	NAD(P)H dehydrogenase (quinone) activity
DIC78_RS13045	COG3103	Sh3 type 3 domain protein
DIC78_RS13050	COG1879	ABC-type sugar transport system periplasmic component
DIC78_RS13055	COG1172	Belongs to the binding-protein-dependent transport system permease family
DIC78_RS13060	COG1129	ABC transporter
DIC78_RS13065	COG1869	D-ribose catabolic process
DIC78_RS13070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIC78_RS13075	COG1609	Transcriptional regulator
DIC78_RS13080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DIC78_RS13090	COG2843	Capsule synthesis protein
DIC78_RS13100	COG0791	NLP P60 protein
DIC78_RS13105	COG0561	phosphatase activity
DIC78_RS13110	COG1316	TRANSCRIPTIONal
DIC78_RS13115	COG2814	Major facilitator Superfamily
DIC78_RS13125	COG0814	amino acid
DIC78_RS13130	COG0697	spore germination
DIC78_RS13135	COG1482	cell wall glycoprotein biosynthetic process
DIC78_RS13140	COG4193	domain, Protein
DIC78_RS13185	COG0463	Glycosyl transferase, family 2
DIC78_RS13205	COG1682	transport, permease protein
DIC78_RS13210	COG1134	teichoic acid transport
DIC78_RS13215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DIC78_RS13235	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DIC78_RS13240	COG1316	TRANSCRIPTIONal
DIC78_RS13250	COG2247	cell wall binding repeat
DIC78_RS13250	COG2385	sporulation resulting in formation of a cellular spore
DIC78_RS13255	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS13255	COG2247	cell wall binding repeat
DIC78_RS13270	COG2244	polysaccharide biosynthetic process
DIC78_RS13275	COG0297	glycogen (starch) synthase activity
DIC78_RS13275	COG0438	transferase activity, transferring glycosyl groups
DIC78_RS13280	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DIC78_RS13285	COG3307	-O-antigen
DIC78_RS13290	COG3206	protein involved in exopolysaccharide biosynthesis
DIC78_RS13295	COG1215	transferase activity, transferring glycosyl groups
DIC78_RS13300	COG0438	transferase activity, transferring glycosyl groups
DIC78_RS13305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DIC78_RS13310	COG1316	TRANSCRIPTIONal
DIC78_RS13315	COG1739	Uncharacterized protein family UPF0029
DIC78_RS13320	COG4585	Histidine kinase
DIC78_RS13325	COG2197	response regulator
DIC78_RS13330	COG1307	EDD domain protein, DegV family
DIC78_RS13335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DIC78_RS13345	COG1040	competence protein
DIC78_RS13355	COG2747	anti-sigma28 factor FlgM
DIC78_RS13360	COG3418	PFAM FlgN family protein
DIC78_RS13365	COG1256	bacterial-type flagellum assembly
DIC78_RS13365	COG4786	Flagellar basal body rod
DIC78_RS13370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DIC78_RS13380	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DIC78_RS13385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DIC78_RS13390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DIC78_RS13395	COG1334	flagellar protein FlaG
DIC78_RS13400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DIC78_RS13405	COG1516	flagellar protein fliS
DIC78_RS13420	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DIC78_RS13425	COG0653	protein targeting
DIC78_RS13435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS13440	COG2010	Cytochrome c
DIC78_RS13445	COG2884	Cell division ATP-binding protein ftsE
DIC78_RS13450	COG2177	Part of the ABC transporter FtsEX involved in
DIC78_RS13455	COG0793	Belongs to the peptidase S41A family
DIC78_RS13455	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS13465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIC78_RS13470	COG2814	Major facilitator Superfamily
DIC78_RS13475	COG1309	transcriptional regulator
DIC78_RS13480	COG3848	Pyruvate phosphate dikinase
DIC78_RS13480	COG0574	Belongs to the PEP-utilizing enzyme family
DIC78_RS13485	COG4897	Protein conserved in bacteria
DIC78_RS13495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DIC78_RS13510	COG3595	metallopeptidase activity
DIC78_RS13515	COG1983	PspC domain protein
DIC78_RS13520	COG1950	PFAM Membrane protein of
DIC78_RS13525	COG2814	Major facilitator Superfamily
DIC78_RS13530	COG1846	Transcriptional regulator
DIC78_RS13540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DIC78_RS13545	COG2188	Transcriptional regulator
DIC78_RS13550	COG0363	glucosamine-6-phosphate deaminase activity
DIC78_RS13555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DIC78_RS13560	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DIC78_RS13565	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DIC78_RS13570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DIC78_RS13575	COG0546	phosphoglycolate phosphatase activity
DIC78_RS13580	COG0110	maltose O-acetyltransferase activity
DIC78_RS13585	COG5297	Belongs to the glycosyl hydrolase family 6
DIC78_RS13590	COG4990	cell redox homeostasis
DIC78_RS13595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DIC78_RS13600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DIC78_RS13605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DIC78_RS13610	COG0131	Imidazoleglycerol-phosphate dehydratase
DIC78_RS13615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DIC78_RS13620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DIC78_RS13625	COG0107	imidazoleglycerol-phosphate synthase activity
DIC78_RS13630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DIC78_RS13630	COG0140	phosphoribosyl-ATP diphosphatase activity
DIC78_RS13650	COG1132	(ABC) transporter
DIC78_RS13655	COG0457	Tetratricopeptide repeat
DIC78_RS13660	COG3883	PFAM NLP P60 protein
DIC78_RS13660	COG0791	NLP P60 protein
DIC78_RS13665	COG0492	ferredoxin-NADP+ reductase activity
DIC78_RS13670	COG1051	belongs to the nudix hydrolase family
DIC78_RS13675	COG1660	Displays ATPase and GTPase activities
DIC78_RS13680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DIC78_RS13685	COG1481	regulation of sporulation
DIC78_RS13690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS13695	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DIC78_RS13705	COG0745	RESPONSE REGULATOR receiver
DIC78_RS13710	COG5002	protein histidine kinase activity
DIC78_RS13715	COG1136	(ABC) transporter
DIC78_RS13720	COG0577	efflux transmembrane transporter activity
DIC78_RS13725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DIC78_RS13730	COG0288	reversible hydration of carbon dioxide
DIC78_RS13735	COG0659	secondary active sulfate transmembrane transporter activity
DIC78_RS13740	COG1694	Mazg nucleotide pyrophosphohydrolase
DIC78_RS13745	COG1611	Belongs to the LOG family
DIC78_RS13765	COG2076	Multidrug Resistance protein
DIC78_RS13770	COG2076	Multidrug Resistance protein
DIC78_RS13775	COG1309	transcriptional regulator
DIC78_RS13780	COG0531	amino acid
DIC78_RS13785	COG1621	beta-fructofuranosidase activity
DIC78_RS13790	COG1621	beta-fructofuranosidase activity
DIC78_RS13795	COG0640	Transcriptional regulator
DIC78_RS13800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DIC78_RS13805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DIC78_RS13815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DIC78_RS13820	COG1794	racemase activity, acting on amino acids and derivatives
DIC78_RS13830	COG3479	Phenolic acid decarboxylase
DIC78_RS13840	COG2272	Belongs to the type-B carboxylesterase lipase family
DIC78_RS13845	COG1396	sequence-specific DNA binding
DIC78_RS13850	COG3944	biosynthesis protein
DIC78_RS13855	COG0489	protein tyrosine kinase activity
DIC78_RS13860	COG1086	Polysaccharide biosynthesis protein
DIC78_RS13865	COG0438	transferase activity, transferring glycosyl groups
DIC78_RS13870	COG1215	transferase activity, transferring glycosyl groups
DIC78_RS13875	COG0438	transferase activity, transferring glycosyl groups
DIC78_RS13885	COG1216	Glycosyl transferase, family 2
DIC78_RS13890	COG5039	Polysaccharide pyruvyl transferase
DIC78_RS13895	COG1216	Glycosyl transferase, family 2
DIC78_RS13900	COG2244	polysaccharide biosynthetic process
DIC78_RS13905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DIC78_RS13910	COG0110	maltose O-acetyltransferase activity
DIC78_RS13915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIC78_RS13920	COG5039	Polysaccharide pyruvyl transferase
DIC78_RS13930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DIC78_RS13935	COG1620	l-lactate permease
DIC78_RS13940	COG2186	Transcriptional regulator
DIC78_RS13945	COG1609	Transcriptional regulator
DIC78_RS13950	COG2182	Extracellular solute-binding protein
DIC78_RS13955	COG1175	transmembrane transport
DIC78_RS13960	COG3833	ABC-type maltose transport systems, permease component
DIC78_RS13965	COG1874	Beta-galactosidase
DIC78_RS13970	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DIC78_RS13975	COG2208	phosphoserine phosphatase activity
DIC78_RS13980	COG0596	Alpha beta hydrolase
DIC78_RS13985	COG1131	(ABC) transporter
DIC78_RS13990	COG0842	Transport permease protein
DIC78_RS13995	COG4585	Histidine kinase
DIC78_RS14000	COG2197	response regulator
DIC78_RS14010	COG0247	lactate metabolic process
DIC78_RS14015	COG1139	Iron-sulfur cluster binding protein
DIC78_RS14020	COG1556	Lactate utilization protein
DIC78_RS14030	COG1113	amino acid transport
DIC78_RS14035	COG0697	spore germination
DIC78_RS14040	COG0583	DNA-binding transcription factor activity
DIC78_RS14045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS14050	COG1609	Transcriptional regulator
DIC78_RS14055	COG2814	Major facilitator Superfamily
DIC78_RS14060	COG2390	Transcriptional regulator
DIC78_RS14065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DIC78_RS14070	COG0126	phosphoglycerate kinase activity
DIC78_RS14075	COG0149	triose-phosphate isomerase activity
DIC78_RS14080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DIC78_RS14090	COG2234	aminopeptidase activity
DIC78_RS14100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DIC78_RS14105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIC78_RS14125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIC78_RS14140	COG0456	acetyltransferase
DIC78_RS14145	COG4640	response to antibiotic
DIC78_RS14150	COG3064	Membrane
DIC78_RS14160	COG1510	regulation of RNA biosynthetic process
DIC78_RS14165	COG1125	glycine betaine transport
DIC78_RS14165	COG0517	IMP dehydrogenase activity
DIC78_RS14170	COG1174	glycine betaine transport
DIC78_RS14175	COG1732	Glycine betaine
DIC78_RS14180	COG1174	glycine betaine transport
DIC78_RS14185	COG0640	Transcriptional regulator
DIC78_RS14190	COG5658	integral membrane protein
DIC78_RS14210	COG1510	regulation of RNA biosynthetic process
DIC78_RS14215	COG1125	glycine betaine transport
DIC78_RS14215	COG0517	IMP dehydrogenase activity
DIC78_RS14220	COG1174	glycine betaine transport
DIC78_RS14225	COG1732	Glycine betaine
DIC78_RS14230	COG1174	glycine betaine transport
DIC78_RS14235	COG0840	transmembrane signaling receptor activity
DIC78_RS14240	COG1733	regulation of RNA biosynthetic process
DIC78_RS14245	COG1396	sequence-specific DNA binding
DIC78_RS14250	COG1396	sequence-specific DNA binding
DIC78_RS14255	COG1476	TRANSCRIPTIONal
DIC78_RS14260	COG0596	Alpha beta hydrolase
DIC78_RS14265	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DIC78_RS14270	COG1647	Serine aminopeptidase, S33
DIC78_RS14275	COG0557	exoribonuclease II activity
DIC78_RS14280	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DIC78_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS14305	COG1309	transcriptional regulator
DIC78_RS14310	COG2076	Multidrug Resistance protein
DIC78_RS14320	COG0697	spore germination
DIC78_RS14325	COG1802	Transcriptional regulator
DIC78_RS14330	COG1289	transmembrane transporter activity
DIC78_RS14335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DIC78_RS14340	COG0673	inositol 2-dehydrogenase activity
DIC78_RS14345	COG1937	Protein conserved in bacteria
DIC78_RS14350	COG2608	mercury ion transmembrane transporter activity
DIC78_RS14355	COG2217	Heavy metal translocating P-type atpase
DIC78_RS14360	COG2217	Heavy metal translocating P-type atpase
DIC78_RS14365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DIC78_RS14370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DIC78_RS14380	COG2860	membrane
DIC78_RS14390	COG3973	AAA domain
DIC78_RS14395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DIC78_RS14400	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DIC78_RS14405	COG0025	NhaP-type Na H and K H
DIC78_RS14415	COG0656	L-ascorbic acid biosynthetic process
DIC78_RS14420	COG4149	molybdate abc transporter
DIC78_RS14425	COG0725	ABC transporter, periplasmic molybdate-binding protein
DIC78_RS14430	COG1910	domain protein
DIC78_RS14435	COG1368	sulfuric ester hydrolase activity
DIC78_RS14440	COG1988	membrane-bound metal-dependent
DIC78_RS14450	COG0531	amino acid
DIC78_RS14460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIC78_RS14465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS14470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS14475	COG1120	ATPase activity
DIC78_RS14480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DIC78_RS14485	COG1136	(ABC) transporter
DIC78_RS14490	COG0577	efflux transmembrane transporter activity
DIC78_RS14500	COG2140	Oxalate decarboxylase
DIC78_RS14510	COG1191	sigma factor activity
DIC78_RS14520	COG0745	RESPONSE REGULATOR receiver
DIC78_RS14525	COG2205	protein histidine kinase activity
DIC78_RS14530	COG3386	PFAM SMP-30 Gluconolaconase
DIC78_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS14540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DIC78_RS14545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DIC78_RS14550	COG1120	ATPase activity
DIC78_RS14555	COG2096	Adenosyltransferase
DIC78_RS14560	COG2814	Major facilitator Superfamily
DIC78_RS14565	COG4758	membrane
DIC78_RS14570	COG1842	Phage shock protein A
DIC78_RS14575	COG3595	metallopeptidase activity
DIC78_RS14580	COG4758	membrane
DIC78_RS14585	COG4585	Histidine kinase
DIC78_RS14590	COG2197	response regulator
DIC78_RS14600	COG0814	amino acid
DIC78_RS14605	COG0697	spore germination
DIC78_RS14615	COG0114	fumarate hydratase activity
DIC78_RS14620	COG1309	transcriptional regulator
DIC78_RS14630	COG2205	protein histidine kinase activity
DIC78_RS14630	COG2770	Histidine kinase
DIC78_RS14635	COG0745	RESPONSE REGULATOR receiver
DIC78_RS14640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DIC78_RS14645	COG0783	Belongs to the Dps family
DIC78_RS14650	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS14665	COG1120	ATPase activity
DIC78_RS14675	COG0583	DNA-binding transcription factor activity
DIC78_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS14685	COG1942	4-Oxalocrotonate Tautomerase
DIC78_RS14690	COG0477	Major facilitator Superfamily
DIC78_RS14695	COG1846	Transcriptional regulator
DIC78_RS14700	COG5577	PFAM Coat F domain
DIC78_RS14710	COG0506	proline dehydrogenase activity
DIC78_RS14720	COG1024	Enoyl-CoA hydratase
DIC78_RS14720	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIC78_RS14725	COG0183	Belongs to the thiolase family
DIC78_RS14730	COG1960	acyl-CoA dehydrogenase activity
DIC78_RS14735	COG1393	Belongs to the ArsC family
DIC78_RS14740	COG0509	glycine decarboxylation via glycine cleavage system
DIC78_RS14750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DIC78_RS14755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS14765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DIC78_RS14770	COG2011	ABC-type metal ion transport system permease component
DIC78_RS14775	COG1464	Belongs to the NlpA lipoprotein family
DIC78_RS14780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DIC78_RS14790	COG0396	ATPase activity
DIC78_RS14795	COG0719	Fe-S assembly protein
DIC78_RS14800	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DIC78_RS14805	COG0822	iron-sulfur transferase activity
DIC78_RS14810	COG0719	Fe-S assembly protein
DIC78_RS14830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DIC78_RS14855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DIC78_RS14860	COG0322	excinuclease ABC activity
DIC78_RS14865	COG2222	sugar isomerase
DIC78_RS14870	COG1653	transport
DIC78_RS14875	COG1175	transmembrane transport
DIC78_RS14880	COG0395	ABC-type sugar transport system, permease component
DIC78_RS14885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIC78_RS14890	COG2188	Transcriptional regulator
DIC78_RS14895	COG3842	ATPase activity
DIC78_RS14900	COG2356	endonuclease I
DIC78_RS14905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIC78_RS14910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DIC78_RS14915	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DIC78_RS14920	COG2068	MobA-Related Protein
DIC78_RS14925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
DIC78_RS14930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DIC78_RS14935	COG2080	2 iron, 2 sulfur cluster binding
DIC78_RS14945	COG2351	hydroxyisourate hydrolase activity
DIC78_RS14950	COG3195	allantoin biosynthetic process
DIC78_RS14950	COG3648	Uricase
DIC78_RS14955	COG2233	PERMEase
DIC78_RS14960	COG2233	PERMEase
DIC78_RS14965	COG2508	Transcriptional regulator
DIC78_RS14970	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DIC78_RS14980	COG1801	Protein of unknown function DUF72
DIC78_RS14985	COG0730	response to heat
DIC78_RS14990	COG0737	Belongs to the 5'-nucleotidase family
DIC78_RS14995	COG3377	Domain of unknown function (DUF1805)
DIC78_RS15005	COG0739	heme binding
DIC78_RS15020	COG4470	Protein conserved in bacteria
DIC78_RS15025	COG2445	Protein of unknown function DUF86
DIC78_RS15030	COG0647	UMP catabolic process
DIC78_RS15035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DIC78_RS15040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DIC78_RS15045	COG0460	homoserine dehydrogenase
DIC78_RS15050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DIC78_RS15055	COG0083	homoserine kinase activity
DIC78_RS15060	COG0823	Involved in the tonB-independent uptake of proteins
DIC78_RS15060	COG1506	peptidase
DIC78_RS15060	COG4946	Tricorn protease homolog
DIC78_RS15065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DIC78_RS15070	COG4837	Protein of unknown function (DUF1462)
DIC78_RS15075	COG1252	NADH dehydrogenase
DIC78_RS15080	COG4844	belongs to the
DIC78_RS15085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DIC78_RS15090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DIC78_RS15095	COG0316	Belongs to the HesB IscA family
DIC78_RS15100	COG0516	GMP reductase activity
DIC78_RS15110	COG0492	ferredoxin-NADP+ reductase activity
DIC78_RS15115	COG1252	NADH dehydrogenase
DIC78_RS15130	COG3584	3D domain protein
DIC78_RS15135	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DIC78_RS15140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DIC78_RS15145	COG2056	Na+-H+ antiporter family
DIC78_RS15150	COG1268	BioY protein
DIC78_RS15155	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DIC78_RS15160	COG2819	hydrolase of the alpha beta superfamily
DIC78_RS15165	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS15170	COG1169	isochorismate synthase
DIC78_RS15175	COG1021	2,3-dihydroxybenzoate-AMP ligase
DIC78_RS15180	COG1535	isochorismatase
DIC78_RS15180	COG3433	isochorismatase activity
DIC78_RS15185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS15190	COG3251	PFAM MbtH domain protein
DIC78_RS15195	COG5634	Uncharacterized conserved protein (DUF2278)
DIC78_RS15200	COG0686	Belongs to the AlaDH PNT family
DIC78_RS15205	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DIC78_RS15205	COG2508	Transcriptional regulator
DIC78_RS15210	COG4842	Belongs to the WXG100 family
DIC78_RS15215	COG5417	Belongs to the EsaB family
DIC78_RS15220	COG4499	WXG100 protein secretion system (Wss), protein YukC
DIC78_RS15225	COG0433	COG0433 Predicted ATPase
DIC78_RS15225	COG1674	ftsk spoiiie
DIC78_RS15230	COG1511	domain protein
DIC78_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS15245	COG1418	mRNA catabolic process
DIC78_RS15260	COG0628	permease
DIC78_RS15275	COG5506	Protein of unknown function (DUF1694)
DIC78_RS15280	COG1335	isochorismatase
DIC78_RS15285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DIC78_RS15290	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DIC78_RS15305	COG0142	geranyltranstransferase activity
DIC78_RS15315	COG4585	Histidine kinase
DIC78_RS15320	COG2197	response regulator
DIC78_RS15325	COG2050	protein possibly involved in aromatic compounds catabolism
DIC78_RS15330	COG1320	monovalent cation:proton antiporter activity
DIC78_RS15335	COG2212	antiporter activity
DIC78_RS15340	COG1863	multisubunit Na H antiporter MnhE subunit
DIC78_RS15345	COG0651	ATP synthesis coupled electron transport
DIC78_RS15350	COG1006	Multisubunit Na H antiporter MnhC subunit
DIC78_RS15355	COG2111	Na H antiporter
DIC78_RS15360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DIC78_RS15360	COG2111	Na H antiporter
DIC78_RS15370	COG3493	citrate carrier protein
DIC78_RS15375	COG1079	Belongs to the binding-protein-dependent transport system permease family
DIC78_RS15380	COG4603	Belongs to the binding-protein-dependent transport system permease family
DIC78_RS15385	COG3845	ABC transporter
DIC78_RS15390	COG1744	ABC transporter substrate-binding protein PnrA-like
DIC78_RS15395	COG4565	transcriptional regulatory protein
DIC78_RS15400	COG3290	protein histidine kinase activity
DIC78_RS15410	COG3011	Protein conserved in bacteria
DIC78_RS15415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIC78_RS15420	COG2814	Major facilitator Superfamily
DIC78_RS15430	COG5018	Exonuclease
DIC78_RS15440	COG2205	protein histidine kinase activity
DIC78_RS15445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DIC78_RS15455	COG2267	carboxylic ester hydrolase activity
DIC78_RS15460	COG1522	sequence-specific DNA binding
DIC78_RS15465	COG0436	Aminotransferase
DIC78_RS15470	COG1098	S1 RNA binding domain
DIC78_RS15475	COG2155	Conserved Protein
DIC78_RS15480	COG1979	alcohol dehydrogenase
DIC78_RS15485	COG1979	alcohol dehydrogenase
DIC78_RS15490	COG0166	Belongs to the GPI family
DIC78_RS15505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DIC78_RS15520	COG2738	Putative neutral zinc metallopeptidase
DIC78_RS15525	COG1253	flavin adenine dinucleotide binding
DIC78_RS15530	COG0366	Alpha amylase catalytic
DIC78_RS15540	COG0432	Pfam Uncharacterised protein family UPF0047
DIC78_RS15545	COG2070	2-Nitropropane dioxygenase
DIC78_RS15560	COG0840	transmembrane signaling receptor activity
DIC78_RS15565	COG0840	transmembrane signaling receptor activity
DIC78_RS15570	COG0840	transmembrane signaling receptor activity
DIC78_RS15575	COG0840	transmembrane signaling receptor activity
DIC78_RS15580	COG3347	Dehydrogenase
DIC78_RS15580	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS15585	COG1349	DNA-binding transcription factor activity
DIC78_RS15590	COG1070	Carbohydrate kinase
DIC78_RS15595	COG3254	rhamnose metabolic process
DIC78_RS15600	COG4806	L-rhamnose isomerase
DIC78_RS15605	COG0673	inositol 2-dehydrogenase activity
DIC78_RS15610	COG0628	permease
DIC78_RS15615	COG1968	undecaprenyl-diphosphatase activity
DIC78_RS15625	COG0582	viral genome integration into host DNA
DIC78_RS15630	COG2856	Zn peptidase
DIC78_RS15640	COG1396	sequence-specific DNA binding
DIC78_RS15655	COG3646	Phage regulatory protein
DIC78_RS15655	COG3645	SOS response
DIC78_RS15695	COG3935	DnaD domain protein
DIC78_RS15700	COG1484	DNA-dependent DNA replication
DIC78_RS15775	COG3677	Transposase
DIC78_RS15785	COG5484	DNA packaging
DIC78_RS15890	COG4824	toxin secretion phage lysis holin
DIC78_RS15895	COG5632	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS15895	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS15920	COG5553	Cysteine dioxygenase type I
DIC78_RS15925	COG0477	Major facilitator Superfamily
DIC78_RS15930	COG1705	Flagellar rod assembly protein muramidase FlgJ
DIC78_RS15935	COG4682	membrane
DIC78_RS15940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DIC78_RS15945	COG0569	domain protein
DIC78_RS15955	COG1510	regulation of RNA biosynthetic process
DIC78_RS15960	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS15965	COG1454	alcohol dehydrogenase
DIC78_RS15975	COG2318	DinB family
DIC78_RS15980	COG1585	Membrane protein implicated in regulation of membrane protease activity
DIC78_RS15985	COG2268	Band 7 protein
DIC78_RS15990	COG1247	-acetyltransferase
DIC78_RS15995	COG3859	Proton-coupled thiamine transporter YuaJ
DIC78_RS16120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DIC78_RS16125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DIC78_RS16130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DIC78_RS16135	COG0297	glycogen (starch) synthase activity
DIC78_RS16140	COG0058	SHG alpha-glucan phosphorylase activity
DIC78_RS16145	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DIC78_RS16150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DIC78_RS16155	COG1169	isochorismate synthase
DIC78_RS16160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DIC78_RS16165	COG0596	Alpha beta hydrolase
DIC78_RS16170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DIC78_RS16175	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS16180	COG4948	Mandelate Racemase Muconate Lactonizing
DIC78_RS16185	COG0803	Belongs to the bacterial solute-binding protein 9 family
DIC78_RS16190	COG1121	(ABC) transporter
DIC78_RS16195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIC78_RS16195	COG1321	iron dependent repressor
DIC78_RS16200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DIC78_RS16210	COG1294	oxidase, subunit
DIC78_RS16215	COG1271	oxidase subunit
DIC78_RS16220	COG0254	rRNA binding
DIC78_RS16225	COG0288	reversible hydration of carbon dioxide
DIC78_RS16230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DIC78_RS16235	COG1854	S-ribosylhomocysteine lyase activity
DIC78_RS16250	COG0783	Belongs to the Dps family
DIC78_RS16255	COG4824	toxin secretion phage lysis holin
DIC78_RS16260	COG0494	nUDIX hydrolase
DIC78_RS16265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DIC78_RS16270	COG1116	anion transmembrane transporter activity
DIC78_RS16275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DIC78_RS16280	COG1506	peptidase
DIC78_RS16290	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DIC78_RS16295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DIC78_RS16300	COG0367	asparagine synthase
DIC78_RS16305	COG1113	amino acid transport
DIC78_RS16310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DIC78_RS16315	COG2267	carboxylic ester hydrolase activity
DIC78_RS16325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DIC78_RS16330	COG1242	4 iron, 4 sulfur cluster binding
DIC78_RS16345	COG1725	Transcriptional regulator
DIC78_RS16350	COG1131	(ABC) transporter
DIC78_RS16365	COG1136	(ABC) transporter
DIC78_RS16370	COG0577	efflux transmembrane transporter activity
DIC78_RS16375	COG0745	RESPONSE REGULATOR receiver
DIC78_RS16380	COG2205	protein histidine kinase activity
DIC78_RS16385	COG1136	(ABC) transporter
DIC78_RS16390	COG0577	efflux transmembrane transporter activity
DIC78_RS16395	COG2433	Pfam Transposase IS66
DIC78_RS16400	COG2814	Major facilitator Superfamily
DIC78_RS16405	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS16405	COG2202	Pas domain
DIC78_RS16415	COG0495	leucyl-tRNA aminoacylation
DIC78_RS16420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIC78_RS16425	COG1486	melibiose metabolic process
DIC78_RS16430	COG0395	ABC-type sugar transport system, permease component
DIC78_RS16435	COG1175	transmembrane transport
DIC78_RS16440	COG1653	transport
DIC78_RS16445	COG1609	Transcriptional regulator
DIC78_RS16450	COG1073	alpha beta
DIC78_RS16460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIC78_RS16465	COG0156	8-amino-7-oxononanoate synthase activity
DIC78_RS16475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DIC78_RS16480	COG2124	cytochrome p450
DIC78_RS16485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DIC78_RS16490	COG0395	ABC-type sugar transport system, permease component
DIC78_RS16495	COG1653	transport
DIC78_RS16500	COG2207	Transcriptional regulator
DIC78_RS16505	COG4209	transmembrane transport
DIC78_RS16510	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DIC78_RS16515	COG1653	transport
DIC78_RS16520	COG0673	inositol 2-dehydrogenase activity
DIC78_RS16525	COG5578	integral membrane protein
DIC78_RS16535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DIC78_RS16540	COG2081	HI0933 family
DIC78_RS16545	COG2244	polysaccharide biosynthetic process
DIC78_RS16550	COG1187	pseudouridine synthase activity
DIC78_RS16555	COG1349	DNA-binding transcription factor activity
DIC78_RS16560	COG1131	(ABC) transporter
DIC78_RS16565	COG4473	ABC transporter
DIC78_RS16570	COG2252	PERMEase
DIC78_RS16575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIC78_RS16580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DIC78_RS16585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DIC78_RS16595	COG1597	lipid kinase activity
DIC78_RS16600	COG1523	belongs to the glycosyl hydrolase 13 family
DIC78_RS16605	COG0510	thiamine kinase activity
DIC78_RS16615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DIC78_RS16620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS16625	COG0281	malic enzyme
DIC78_RS16630	COG5584	Small secreted protein
DIC78_RS16635	COG1363	Peptidase, m42
DIC78_RS16650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS16655	COG4848	Belongs to the UPF0354 family
DIC78_RS16660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIC78_RS16665	COG1674	ftsk spoiiie
DIC78_RS16670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DIC78_RS16675	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DIC78_RS16680	COG4980	gas vesicle protein
DIC78_RS16685	COG3118	belongs to the thioredoxin family
DIC78_RS16690	COG1605	Chorismate mutase
DIC78_RS16690	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DIC78_RS16695	COG1609	Transcriptional regulator
DIC78_RS16700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DIC78_RS16705	COG1360	Flagellar Motor Protein
DIC78_RS16710	COG0123	including yeast histone deacetylase and acetoin utilization protein
DIC78_RS16715	COG0517	IMP dehydrogenase activity
DIC78_RS16720	COG0454	-acetyltransferase
DIC78_RS16725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIC78_RS16730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DIC78_RS16745	COG2203	Gaf domain
DIC78_RS16745	COG2199	diguanylate cyclase activity
DIC78_RS16750	COG1956	GAF domain-containing protein
DIC78_RS16755	COG1309	transcriptional regulator
DIC78_RS16760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DIC78_RS16765	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DIC78_RS16770	COG1114	Component of the transport system for branched-chain amino acids
DIC78_RS16775	COG1104	cysteine desulfurase activity
DIC78_RS16780	COG0301	tRNA thio-modification
DIC78_RS16790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DIC78_RS16795	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DIC78_RS16800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DIC78_RS16805	COG0616	signal peptide processing
DIC78_RS16810	COG1714	RDD family
DIC78_RS16820	COG3874	Sporulation protein YtfJ
DIC78_RS16825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DIC78_RS16830	COG0827	DNA restriction-modification system
DIC78_RS16835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DIC78_RS16840	COG0521	Mo-molybdopterin cofactor biosynthetic process
DIC78_RS16845	COG0137	argininosuccinate synthase activity
DIC78_RS16850	COG0165	Argininosuccinate lyase
DIC78_RS16860	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS16865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DIC78_RS16870	COG0583	DNA-binding transcription factor activity
DIC78_RS16875	COG0454	-acetyltransferase
DIC78_RS16880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS16885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS16890	COG0765	amino acid transport
DIC78_RS16895	COG0765	amino acid transport
DIC78_RS16900	COG1126	abc transporter atp-binding protein
DIC78_RS16905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS16910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DIC78_RS16915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DIC78_RS16920	COG0196	riboflavin kinase activity
DIC78_RS16925	COG1473	amidohydrolase
DIC78_RS16930	COG0730	response to heat
DIC78_RS16935	COG4109	DRTGG domain
DIC78_RS16945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DIC78_RS16965	COG0587	DNA-directed DNA polymerase activity
DIC78_RS16970	COG0281	malic enzyme
DIC78_RS16975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DIC78_RS16980	COG0825	malonyl-CoA metabolic process
DIC78_RS16985	COG0205	6-phosphofructokinase activity
DIC78_RS16990	COG0469	pyruvate kinase activity
DIC78_RS16995	COG3030	protein affecting phage T7 exclusion by the F plasmid
DIC78_RS17000	COG0628	permease
DIC78_RS17005	COG2707	UPF0756 membrane protein
DIC78_RS17010	COG0372	Belongs to the citrate synthase family
DIC78_RS17015	COG0538	isocitrate dehydrogenase activity
DIC78_RS17020	COG0039	L-malate dehydrogenase activity
DIC78_RS17025	COG0745	RESPONSE REGULATOR receiver
DIC78_RS17030	COG5002	protein histidine kinase activity
DIC78_RS17035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIC78_RS17035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIC78_RS17040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DIC78_RS17045	COG1971	Probably functions as a manganese efflux pump
DIC78_RS17050	COG0237	dephospho-CoA kinase activity
DIC78_RS17055	COG0656	L-ascorbic acid biosynthetic process
DIC78_RS17060	COG2814	Major facilitator Superfamily
DIC78_RS17065	COG1733	regulation of RNA biosynthetic process
DIC78_RS17070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DIC78_RS17075	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DIC78_RS17080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DIC78_RS17085	COG3611	Membrane attachment protein
DIC78_RS17090	COG1484	DNA-dependent DNA replication
DIC78_RS17095	COG0398	Pfam SNARE associated Golgi protein
DIC78_RS17105	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DIC78_RS17110	COG1011	Hydrolase
DIC78_RS17115	COG3275	phosphorelay sensor kinase activity
DIC78_RS17120	COG3279	Response regulator of the LytR AlgR family
DIC78_RS17125	COG1380	Effector of murein hydrolase LrgA
DIC78_RS17130	COG1346	cytolysis
DIC78_RS17140	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DIC78_RS17145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DIC78_RS17150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DIC78_RS17155	COG3326	Membrane
DIC78_RS17165	COG1363	Peptidase, m42
DIC78_RS17170	COG3507	Belongs to the glycosyl hydrolase 43 family
DIC78_RS17175	COG2160	L-arabinose isomerase activity
DIC78_RS17180	COG1069	ribulokinase activity
DIC78_RS17185	COG0235	Class ii aldolase
DIC78_RS17190	COG0647	UMP catabolic process
DIC78_RS17195	COG0371	Dehydrogenase
DIC78_RS17200	COG1653	transport
DIC78_RS17205	COG1175	transmembrane transport
DIC78_RS17210	COG0395	ABC-type sugar transport system, permease component
DIC78_RS17215	COG3534	alpha-L-arabinofuranosidase
DIC78_RS17220	COG1695	Transcriptional regulator
DIC78_RS17235	COG1966	Carbon starvation protein
DIC78_RS17240	COG0346	lactoylglutathione lyase activity
DIC78_RS17245	COG0247	lactate metabolic process
DIC78_RS17250	COG0277	FAD linked oxidase domain protein
DIC78_RS17255	COG3835	regulator
DIC78_RS17265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DIC78_RS17275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DIC78_RS17280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIC78_RS17280	COG0072	phenylalanine-tRNA ligase activity
DIC78_RS17285	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DIC78_RS17290	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DIC78_RS17295	COG1286	toxin biosynthetic process
DIC78_RS17300	COG1796	DNA polymerase
DIC78_RS17300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DIC78_RS17305	COG1193	negative regulation of DNA recombination
DIC78_RS17310	COG3766	membrane
DIC78_RS17315	COG0318	PFAM AMP-dependent synthetase and ligase
DIC78_RS17320	COG1309	transcriptional regulator
DIC78_RS17325	COG1024	Enoyl-CoA hydratase
DIC78_RS17330	COG2086	electron transfer activity
DIC78_RS17335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DIC78_RS17340	COG3534	alpha-L-arabinofuranosidase
DIC78_RS17345	COG3118	belongs to the thioredoxin family
DIC78_RS17350	COG0322	excinuclease ABC activity
DIC78_RS17360	COG0527	aspartate kinase activity
DIC78_RS17365	COG1719	4-vinyl reductase, 4VR
DIC78_RS17370	COG2009	succinate dehydrogenase
DIC78_RS17375	COG1053	succinate dehydrogenase
DIC78_RS17380	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DIC78_RS17385	COG0824	Thioesterase
DIC78_RS17390	COG2197	response regulator
DIC78_RS17395	COG1846	Transcriptional regulator
DIC78_RS17400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DIC78_RS17405	COG5401	PFAM Sporulation and spore germination
DIC78_RS17410	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DIC78_RS17415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DIC78_RS17420	COG0622	Phosphoesterase
DIC78_RS17430	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
DIC78_RS17435	COG0454	-acetyltransferase
DIC78_RS17445	COG0028	Belongs to the TPP enzyme family
DIC78_RS17450	COG0440	acetolactate synthase activity
DIC78_RS17455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DIC78_RS17460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DIC78_RS17465	COG0473	3-isopropylmalate dehydrogenase activity
DIC78_RS17470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DIC78_RS17475	COG0066	3-isopropylmalate dehydratase activity
DIC78_RS17480	COG0457	Tetratricopeptide repeat
DIC78_RS17480	COG1477	protein flavinylation
DIC78_RS17485	COG0544	peptidyl-prolyl cis-trans isomerase activity
DIC78_RS17490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DIC78_RS17495	COG0470	DNA polymerase III
DIC78_RS17495	COG1067	ATP-dependent peptidase activity
DIC78_RS17500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DIC78_RS17505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DIC78_RS17515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DIC78_RS17520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DIC78_RS17525	COG0181	hydroxymethylbilane synthase activity
DIC78_RS17530	COG1587	Uroporphyrinogen-III synthase
DIC78_RS17535	COG0113	porphobilinogen synthase activity
DIC78_RS17540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DIC78_RS17545	COG1388	LysM domain
DIC78_RS17550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DIC78_RS17560	COG0525	valine-tRNA ligase activity
DIC78_RS17565	COG0285	dihydrofolate synthase activity
DIC78_RS17570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DIC78_RS17580	COG0424	maF-like protein
DIC78_RS17585	COG2003	Belongs to the UPF0758 family
DIC78_RS17590	COG1077	Cell shape determining protein MreB Mrl
DIC78_RS17600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DIC78_RS17605	COG0850	regulation of cytokinetic process
DIC78_RS17610	COG2894	cell division
DIC78_RS17615	COG0739	heme binding
DIC78_RS17620	COG1994	Peptidase M50
DIC78_RS17625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DIC78_RS17630	COG2868	ribosomal protein
DIC78_RS17635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DIC78_RS17645	COG3290	protein histidine kinase activity
DIC78_RS17650	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DIC78_RS17655	COG4492	Belongs to the UPF0735 family
DIC78_RS17660	COG0077	Prephenate dehydratase
DIC78_RS17665	COG1827	regulation of RNA biosynthetic process
DIC78_RS17670	COG1104	cysteine desulfurase activity
DIC78_RS17675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DIC78_RS17680	COG0157	Belongs to the NadC ModD family
DIC78_RS17685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DIC78_RS17690	COG1388	LysM domain
DIC78_RS17700	COG0217	transcriptional regulatory protein
DIC78_RS17705	COG1115	amino acid carrier protein
DIC78_RS17720	COG2112	serine threonine protein kinase
DIC78_RS17725	COG0673	inositol 2-dehydrogenase activity
DIC78_RS17730	COG2814	Major facilitator Superfamily
DIC78_RS17740	COG0632	four-way junction helicase activity
DIC78_RS17745	COG2255	four-way junction helicase activity
DIC78_RS17755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DIC78_RS17760	COG0343	queuine tRNA-ribosyltransferase activity
DIC78_RS17765	COG1862	Preprotein translocase
DIC78_RS17775	COG2323	membrane
DIC78_RS17780	COG2244	polysaccharide biosynthetic process
DIC78_RS17790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIC78_RS17790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DIC78_RS17795	COG0490	domain, Protein
DIC78_RS17800	COG5416	Lipopolysaccharide assembly protein A domain
DIC78_RS17805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DIC78_RS17805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DIC78_RS17810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIC78_RS17815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DIC78_RS17820	COG1490	D-aminoacyl-tRNA deacylase activity
DIC78_RS17825	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS17825	COG4991	sh3 domain protein
DIC78_RS17825	COG3103	Sh3 type 3 domain protein
DIC78_RS17835	COG0124	histidyl-tRNA synthetase
DIC78_RS17840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DIC78_RS17850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DIC78_RS17855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DIC78_RS17860	COG1959	2 iron, 2 sulfur cluster binding
DIC78_RS17865	COG1104	cysteine desulfurase activity
DIC78_RS17870	COG0482	sulfurtransferase activity
DIC78_RS17875	COG0457	Tetratricopeptide repeat
DIC78_RS17880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DIC78_RS17885	COG3881	PFAM PRC-barrel domain
DIC78_RS17900	COG0765	amino acid transport
DIC78_RS17905	COG0765	amino acid transport
DIC78_RS17910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS17915	COG1126	abc transporter atp-binding protein
DIC78_RS17920	COG0628	permease
DIC78_RS17925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DIC78_RS17930	COG4472	Bacterial protein of unknown function (DUF965)
DIC78_RS17935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DIC78_RS17940	COG3906	Belongs to the UPF0473 family
DIC78_RS17945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIC78_RS17950	COG4122	O-methyltransferase activity
DIC78_RS17955	COG0826	peptidase U32
DIC78_RS17960	COG0826	peptidase U32
DIC78_RS17965	COG0572	uridine kinase
DIC78_RS17970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DIC78_RS17975	COG0768	penicillin binding
DIC78_RS17990	COG2226	methyltransferase
DIC78_RS17995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DIC78_RS18000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DIC78_RS18005	COG0626	cystathionine gamma-synthase activity
DIC78_RS18015	COG2427	Protein of unknown function (DUF1641)
DIC78_RS18020	COG3383	formate dehydrogenase (NAD+) activity
DIC78_RS18025	COG5609	conserved protein (DUF2294)
DIC78_RS18030	COG2116	formate transmembrane transporter activity
DIC78_RS18045	COG2226	methyltransferase
DIC78_RS18050	COG1309	transcriptional regulator
DIC78_RS18055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DIC78_RS18055	COG2124	cytochrome p450
DIC78_RS18065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DIC78_RS18065	COG2755	lipolytic protein G-D-S-L family
DIC78_RS18075	COG1595	DNA-templated transcription, initiation
DIC78_RS18080	COG1378	Sugar-specific transcriptional regulator TrmB
DIC78_RS18085	COG1280	lysine exporter protein (LysE YggA)
DIC78_RS18090	COG1113	amino acid transport
DIC78_RS18095	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DIC78_RS18095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DIC78_RS18100	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DIC78_RS18105	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DIC78_RS18110	COG3715	PTS system
DIC78_RS18115	COG3716	PTS system mannose fructose sorbose family IID component
DIC78_RS18125	COG0693	protein deglycase activity
DIC78_RS18130	COG1064	alcohol dehydrogenase
DIC78_RS18140	COG0789	Transcriptional regulator
DIC78_RS18165	COG4991	sh3 domain protein
DIC78_RS18170	COG4991	sh3 domain protein
DIC78_RS18180	COG3443	Belongs to the bacterial solute-binding protein 9 family
DIC78_RS18185	COG4608	Belongs to the ABC transporter superfamily
DIC78_RS18190	COG0444	Belongs to the ABC transporter superfamily
DIC78_RS18195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DIC78_RS18200	COG0601	transmembrane transport
DIC78_RS18205	COG0747	negative chemotaxis
DIC78_RS18225	COG1725	Transcriptional regulator
DIC78_RS18230	COG1131	(ABC) transporter
DIC78_RS18250	COG2732	(Barnase) inhibitor
DIC78_RS18285	COG1733	regulation of RNA biosynthetic process
DIC78_RS18290	COG2085	NADP oxidoreductase coenzyme F420-dependent
DIC78_RS18300	COG0583	DNA-binding transcription factor activity
DIC78_RS18305	COG0114	fumarate hydratase activity
DIC78_RS18320	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DIC78_RS18340	COG1309	transcriptional regulator
DIC78_RS18350	COG0509	glycine decarboxylation via glycine cleavage system
DIC78_RS18360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS18375	COG0492	ferredoxin-NADP+ reductase activity
DIC78_RS18395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DIC78_RS18400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS18425	COG0563	adenylate kinase activity
DIC78_RS18440	COG5632	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS18440	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS18445	COG0697	spore germination
DIC78_RS18475	COG1230	cation diffusion facilitator family transporter
DIC78_RS18480	COG2072	flavoprotein involved in K transport
DIC78_RS18485	COG0457	Tetratricopeptide repeat
DIC78_RS18490	COG2814	Major facilitator Superfamily
DIC78_RS18505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DIC78_RS18535	COG3209	COG3209 Rhs family protein
DIC78_RS18545	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DIC78_RS18550	COG0398	Pfam SNARE associated Golgi protein
DIC78_RS18555	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS18555	COG5632	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS18560	COG2755	lipolytic protein G-D-S-L family
DIC78_RS18570	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DIC78_RS18575	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DIC78_RS18580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DIC78_RS18585	COG1534	Rna-binding protein
DIC78_RS18590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DIC78_RS18595	COG1713	HD superfamily hydrolase involved in NAD metabolism
DIC78_RS18600	COG0799	negative regulation of ribosome biogenesis
DIC78_RS18605	COG2226	methyltransferase
DIC78_RS18610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DIC78_RS18615	COG1596	polysaccharide export
DIC78_RS18615	COG1555	photosystem II stabilization
DIC78_RS18620	COG2131	deaminase
DIC78_RS18625	COG2333	competence protein COMEC
DIC78_RS18625	COG0658	competence protein
DIC78_RS18640	COG1466	dna polymerase III delta subunit
DIC78_RS18650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DIC78_RS18655	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS18665	COG0481	GTPase activity
DIC78_RS18670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DIC78_RS18675	COG1420	regulation of RNA biosynthetic process
DIC78_RS18680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DIC78_RS18690	COG0484	heat shock protein binding
DIC78_RS18695	COG2264	protein methyltransferase activity
DIC78_RS18700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DIC78_RS18705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DIC78_RS18710	COG1283	sodium-dependent phosphate transmembrane transporter activity
DIC78_RS18720	COG1610	YqeY-like protein
DIC78_RS18725	COG1030	water channel activity
DIC78_RS18730	COG4864	UPF0365 protein
DIC78_RS18745	COG0561	phosphatase activity
DIC78_RS18750	COG1702	phosphate starvation-inducible protein PhoH
DIC78_RS18755	COG1480	7TM receptor with intracellular HD hydrolase
DIC78_RS18760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DIC78_RS18765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DIC78_RS18770	COG0295	cytidine deaminase activity
DIC78_RS18775	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DIC78_RS18785	COG1381	Involved in DNA repair and RecF pathway recombination
DIC78_RS18790	COG0752	glycyl-tRNA synthetase alpha subunit
DIC78_RS18795	COG0751	glycine-tRNA ligase activity
DIC78_RS18800	COG0517	IMP dehydrogenase activity
DIC78_RS18805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DIC78_RS18810	COG1671	Belongs to the UPF0178 family
DIC78_RS18815	COG0358	DNA primase activity
DIC78_RS18820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DIC78_RS18825	COG2010	Cytochrome c
DIC78_RS18830	COG2384	SAM-dependent methyltransferase
DIC78_RS18835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DIC78_RS18840	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DIC78_RS18850	COG0513	Belongs to the DEAD box helicase family
DIC78_RS18855	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DIC78_RS18865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS18870	COG0735	belongs to the Fur family
DIC78_RS18875	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DIC78_RS18880	COG4709	membrane
DIC78_RS18885	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DIC78_RS18890	COG1388	LysM domain
DIC78_RS18895	COG5521	maltodextrose utilization protein MalA
DIC78_RS18900	COG2839	Protein conserved in bacteria
DIC78_RS18905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DIC78_RS18910	COG0477	Major facilitator Superfamily
DIC78_RS18915	COG0768	penicillin binding
DIC78_RS18920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DIC78_RS18925	COG0573	inorganic phosphate transmembrane transporter activity
DIC78_RS18930	COG0581	inorganic phosphate transmembrane transporter activity
DIC78_RS18935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DIC78_RS18940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DIC78_RS18945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DIC78_RS18960	COG0438	transferase activity, transferring glycosyl groups
DIC78_RS18970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DIC78_RS18980	COG0705	Rhomboid family
DIC78_RS18980	COG0457	Tetratricopeptide repeat
DIC78_RS18985	COG4483	Protein conserved in bacteria
DIC78_RS18990	COG1940	carbohydrate kinase activity
DIC78_RS18995	COG1368	sulfuric ester hydrolase activity
DIC78_RS19000	COG2866	Carboxypeptidase
DIC78_RS19010	COG0011	TIGRFAM Protein of
DIC78_RS19020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS19030	COG1393	Belongs to the ArsC family
DIC78_RS19040	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS19045	COG1253	flavin adenine dinucleotide binding
DIC78_RS19050	COG0598	Magnesium transport protein CorA
DIC78_RS19055	COG0517	IMP dehydrogenase activity
DIC78_RS19060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DIC78_RS19065	COG1459	type II secretion system
DIC78_RS19070	COG4537	Required for transformation and DNA binding
DIC78_RS19075	COG4970	Tfp pilus assembly protein FimT
DIC78_RS19085	COG4940	Competence protein ComGF
DIC78_RS19110	COG0681	Belongs to the peptidase S26 family
DIC78_RS19120	COG1396	sequence-specific DNA binding
DIC78_RS19135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DIC78_RS19140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DIC78_RS19145	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DIC78_RS19150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DIC78_RS19155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DIC78_RS19160	COG0095	Lipoate-protein ligase
DIC78_RS19165	COG1321	iron dependent repressor
DIC78_RS19170	COG1752	Esterase of the alpha-beta hydrolase superfamily
DIC78_RS19180	COG3872	metal-dependent enzyme
DIC78_RS19190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DIC78_RS19195	COG0006	proline dipeptidase activity
DIC78_RS19200	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DIC78_RS19210	COG3854	ATPases associated with a variety of cellular activities
DIC78_RS19250	COG0511	ligase activity, forming carbon-carbon bonds
DIC78_RS19255	COG0439	Biotin carboxylase
DIC78_RS19260	COG1302	Protein conserved in bacteria
DIC78_RS19265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DIC78_RS19270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DIC78_RS19275	COG1570	exodeoxyribonuclease VII activity
DIC78_RS19280	COG1722	exodeoxyribonuclease VII activity
DIC78_RS19285	COG0142	geranyltranstransferase activity
DIC78_RS19290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DIC78_RS19295	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DIC78_RS19300	COG1438	arginine binding
DIC78_RS19305	COG0497	DNA recombination
DIC78_RS19310	COG0750	zinc metalloprotease
DIC78_RS19315	COG0745	RESPONSE REGULATOR receiver
DIC78_RS19325	COG1902	pentaerythritol trinitrate reductase activity
DIC78_RS19340	COG0860	N-Acetylmuramoyl-L-alanine amidase
DIC78_RS19345	COG0584	glycerophosphoryl diester phosphodiesterase
DIC78_RS19350	COG0183	Belongs to the thiolase family
DIC78_RS19355	COG1250	3-hydroxyacyl-CoA dehydrogenase
DIC78_RS19360	COG1960	acyl-CoA dehydrogenase activity
DIC78_RS19365	COG0372	Belongs to the citrate synthase family
DIC78_RS19370	COG2079	MmgE PrpD family protein
DIC78_RS19375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DIC78_RS19385	COG3290	protein histidine kinase activity
DIC78_RS19385	COG3829	transcription factor binding
DIC78_RS19390	COG0280	phosphate acetyltransferase
DIC78_RS19395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIC78_RS19400	COG3426	butyrate kinase activity
DIC78_RS19405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DIC78_RS19410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DIC78_RS19415	COG0022	dehydrogenase e1 component
DIC78_RS19420	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIC78_RS19425	COG4978	Transcriptional regulator
DIC78_RS19425	COG0789	Transcriptional regulator
DIC78_RS19430	COG2814	Major facilitator Superfamily
DIC78_RS19435	COG1597	lipid kinase activity
DIC78_RS19445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DIC78_RS19450	COG0765	amino acid transport
DIC78_RS19455	COG1126	abc transporter atp-binding protein
DIC78_RS19460	COG4129	membrane
DIC78_RS19465	COG1376	ErfK ybiS ycfS ynhG family protein
DIC78_RS19470	COG0346	lactoylglutathione lyase activity
DIC78_RS19475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DIC78_RS19480	COG2195	Cleaves the N-terminal amino acid of tripeptides
DIC78_RS19485	COG3361	conserved protein (COG2071)
DIC78_RS19490	COG0706	membrane insertase activity
DIC78_RS19500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIC78_RS19505	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DIC78_RS19515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DIC78_RS19520	COG1234	tRNA 3'-trailer cleavage
DIC78_RS19530	COG0596	Alpha beta hydrolase
DIC78_RS19535	COG1902	pentaerythritol trinitrate reductase activity
DIC78_RS19540	COG4187	Peptidase family M20/M25/M40
DIC78_RS19545	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DIC78_RS19550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS19555	COG0300	oxidoreductase activity
DIC78_RS19560	COG3048	D-serine ammonia-lyase activity
DIC78_RS19565	COG1072	(Pantothenic acid kinase))
DIC78_RS19570	COG0346	lactoylglutathione lyase activity
DIC78_RS19575	COG2211	Major facilitator Superfamily
DIC78_RS19580	COG3547	Transposase (IS116 IS110 IS902 family)
DIC78_RS19590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DIC78_RS19600	COG0456	acetyltransferase
DIC78_RS19605	COG2329	Antibiotic biosynthesis monooxygenase
DIC78_RS19610	COG0456	acetyltransferase
DIC78_RS19610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DIC78_RS19615	COG4918	Iron-sulphur cluster biosynthesis
DIC78_RS19625	COG1073	alpha beta
DIC78_RS19635	COG0667	Aldo Keto reductase
DIC78_RS19645	COG0494	nUDIX hydrolase
DIC78_RS19650	COG1379	DNA repair
DIC78_RS19655	COG1396	sequence-specific DNA binding
DIC78_RS19660	COG0252	asparaginase activity
DIC78_RS19665	COG1027	Aspartate ammonia-lyase
DIC78_RS19670	COG1757	Na H antiporter
DIC78_RS19675	COG0281	malic enzyme
DIC78_RS19685	COG1300	Membrane
DIC78_RS19690	COG0735	belongs to the Fur family
DIC78_RS19700	COG4974	Belongs to the 'phage' integrase family
DIC78_RS19705	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DIC78_RS19710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DIC78_RS19715	COG1686	Belongs to the peptidase S11 family
DIC78_RS19720	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS19725	COG2172	sigma factor antagonist activity
DIC78_RS19730	COG1191	sigma factor activity
DIC78_RS19750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DIC78_RS19765	COG0697	spore germination
DIC78_RS19770	COG0019	diaminopimelate decarboxylase activity
DIC78_RS19775	COG4086	secreted protein
DIC78_RS19780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DIC78_RS19785	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DIC78_RS19790	COG0681	Belongs to the peptidase S26 family
DIC78_RS19800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DIC78_RS19800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DIC78_RS19805	COG0307	riboflavin synthase, alpha
DIC78_RS19810	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIC78_RS19810	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DIC78_RS19815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DIC78_RS19820	COG0456	acetyltransferase
DIC78_RS19825	COG1547	Domain of unknown function (DUF309)
DIC78_RS19835	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DIC78_RS19840	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DIC78_RS19850	COG1686	Belongs to the peptidase S11 family
DIC78_RS19855	COG2715	membrane protein required for spore maturation
DIC78_RS19860	COG0700	Nucleoside recognition
DIC78_RS19865	COG1187	pseudouridine synthase activity
DIC78_RS19870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DIC78_RS19875	COG1333	cytochrome c biogenesis protein
DIC78_RS19880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DIC78_RS19885	COG0745	RESPONSE REGULATOR receiver
DIC78_RS19890	COG5002	protein histidine kinase activity
DIC78_RS19895	COG1595	DNA-templated transcription, initiation
DIC78_RS19905	COG0710	3-dehydroquinate dehydratase activity
DIC78_RS19910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIC78_RS19915	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DIC78_RS19920	COG1141	Ferredoxin
DIC78_RS19925	COG4955	Helix-turn-helix domain
DIC78_RS19930	COG0514	ATP-dependent DNA helicase (RecQ)
DIC78_RS19935	COG1266	CAAX protease self-immunity
DIC78_RS19940	COG1388	LysM domain
DIC78_RS19950	COG1408	metallophosphoesterase
DIC78_RS19955	COG4862	establishment of competence for transformation
DIC78_RS19960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DIC78_RS19965	COG0492	ferredoxin-NADP+ reductase activity
DIC78_RS19970	COG2339	peptidase activity
DIC78_RS19975	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS19975	COG3773	Cell wall hydrolase
DIC78_RS19980	COG2959	enzyme of heme biosynthesis
DIC78_RS19985	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DIC78_RS19995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DIC78_RS20000	COG0539	negative regulation of cytoplasmic translation
DIC78_RS20005	COG1304	FMN binding
DIC78_RS20030	COG1160	GTP binding
DIC78_RS20035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DIC78_RS20050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DIC78_RS20055	COG0776	regulation of translation
DIC78_RS20060	COG0302	gtp cyclohydrolase
DIC78_RS20070	COG0142	geranyltranstransferase activity
DIC78_RS20075	COG2226	methyltransferase
DIC78_RS20080	COG0142	geranyltranstransferase activity
DIC78_RS20085	COG0105	UTP biosynthetic process
DIC78_RS20090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DIC78_RS20095	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DIC78_RS20100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DIC78_RS20105	COG4401	Chorismate mutase type I
DIC78_RS20110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DIC78_RS20115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DIC78_RS20125	COG0135	phosphoribosylanthranilate isomerase activity
DIC78_RS20130	COG0133	tryptophan synthase activity
DIC78_RS20135	COG0159	tryptophan synthase activity
DIC78_RS20140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DIC78_RS20145	COG0287	Prephenate dehydrogenase
DIC78_RS20150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DIC78_RS20155	COG0457	Tetratricopeptide repeat
DIC78_RS20160	COG5582	Belongs to the UPF0302 family
DIC78_RS20170	COG0723	plastoquinol--plastocyanin reductase activity
DIC78_RS20175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DIC78_RS20180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DIC78_RS20180	COG2010	Cytochrome c
DIC78_RS20185	COG4347	Protein of unknown function (DUF1405)
DIC78_RS20195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DIC78_RS20200	COG1694	Mazg nucleotide pyrophosphohydrolase
DIC78_RS20205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DIC78_RS20210	COG1803	Methylglyoxal synthase
DIC78_RS20215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIC78_RS20220	COG0438	transferase activity, transferring glycosyl groups
DIC78_RS20225	COG0617	tRNA 3'-terminal CCA addition
DIC78_RS20230	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DIC78_RS20230	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DIC78_RS20235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DIC78_RS20240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DIC78_RS20245	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DIC78_RS20250	COG1199	ATP-dependent helicase activity
DIC78_RS20250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DIC78_RS20260	COG5353	protein conserved in bacteria
DIC78_RS20265	COG0436	Aminotransferase
DIC78_RS20270	COG0017	Asparaginyl-tRNA synthetase
DIC78_RS20275	COG3935	DnaD domain protein
DIC78_RS20280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DIC78_RS20290	COG4499	WXG100 protein secretion system (Wss), protein YukC
DIC78_RS20290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DIC78_RS20295	COG3331	DNA recombination
DIC78_RS20330	COG0071	Belongs to the small heat shock protein (HSP20) family
DIC78_RS20335	COG2190	(PTS) system
DIC78_RS20340	COG1205	dead DEAH box helicase
DIC78_RS20340	COG1111	helicase
DIC78_RS20345	COG3359	exonuclease
DIC78_RS20360	COG4474	Belongs to the UPF0398 family
DIC78_RS20375	COG0116	Belongs to the methyltransferase superfamily
DIC78_RS20390	COG1199	ATP-dependent helicase activity
DIC78_RS20395	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS20400	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DIC78_RS20405	COG1609	Transcriptional regulator
DIC78_RS20410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DIC78_RS20415	COG0800	Aldolase
DIC78_RS20425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DIC78_RS20430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DIC78_RS20435	COG2233	PERMEase
DIC78_RS20440	COG3424	synthase
DIC78_RS20445	COG1755	Isoprenylcysteine carboxyl methyltransferase
DIC78_RS20455	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DIC78_RS20470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DIC78_RS20480	COG0328	RNA-DNA hybrid ribonuclease activity
DIC78_RS20485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DIC78_RS20490	COG0328	RNA-DNA hybrid ribonuclease activity
DIC78_RS20510	COG1278	Cold shock
DIC78_RS20515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DIC78_RS20520	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DIC78_RS20525	COG0386	Belongs to the glutathione peroxidase family
DIC78_RS20530	COG1418	mRNA catabolic process
DIC78_RS20535	COG1413	lyase activity
DIC78_RS20540	COG0129	dihydroxy-acid dehydratase activity
DIC78_RS20550	COG2521	methyltransferase
DIC78_RS20550	COG2136	Putative SAM-dependent methyltransferase
DIC78_RS20560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DIC78_RS20570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DIC78_RS20575	COG0204	Acyl-transferase
DIC78_RS20580	COG1272	protein, Hemolysin III
DIC78_RS20585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DIC78_RS20590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DIC78_RS20600	COG1999	signal sequence binding
DIC78_RS20605	COG2755	lipolytic protein G-D-S-L family
DIC78_RS20610	COG4698	Protein conserved in bacteria
DIC78_RS20620	COG0534	Mate efflux family protein
DIC78_RS20625	COG1846	Transcriptional regulator
DIC78_RS20630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DIC78_RS20640	COG1086	Polysaccharide biosynthesis protein
DIC78_RS20645	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
DIC78_RS20655	COG4641	Protein conserved in bacteria
DIC78_RS20670	COG0463	Glycosyl transferase, family 2
DIC78_RS20675	COG0456	acetyltransferase
DIC78_RS20685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DIC78_RS20690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DIC78_RS20695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DIC78_RS20700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DIC78_RS20705	COG0456	acetyltransferase
DIC78_RS20710	COG1509	lysine 2,3-aminomutase activity
DIC78_RS20720	COG4479	Belongs to the UPF0346 family
DIC78_RS20745	COG0671	phosphoesterase, PA-phosphatase related
DIC78_RS20760	COG0813	purine-nucleoside phosphorylase activity
DIC78_RS20765	COG1876	peptidase activity
DIC78_RS20775	COG2226	methyltransferase
DIC78_RS20780	COG3409	Peptidoglycan-binding domain 1 protein
DIC78_RS20780	COG0793	Belongs to the peptidase S41A family
DIC78_RS20785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DIC78_RS20795	COG0346	lactoylglutathione lyase activity
DIC78_RS20800	COG0400	carboxylic ester hydrolase activity
DIC78_RS20805	COG0778	Nitroreductase
DIC78_RS20810	COG1733	regulation of RNA biosynthetic process
DIC78_RS20820	COG1942	4-Oxalocrotonate Tautomerase
DIC78_RS20840	COG2962	Rard protein
DIC78_RS20850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIC78_RS20855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DIC78_RS20860	COG1366	Belongs to the anti-sigma-factor antagonist family
DIC78_RS20865	COG0534	Mate efflux family protein
DIC78_RS20870	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DIC78_RS20875	COG1819	glycosyl
DIC78_RS20880	COG1388	LysM domain
DIC78_RS20880	COG0791	NLP P60 protein
DIC78_RS20885	COG2032	superoxide dismutase activity
DIC78_RS20890	COG0714	Associated with various cellular activities
DIC78_RS20895	COG4548	von Willebrand factor, type A
DIC78_RS20900	COG0567	Dehydrogenase, E1 component
DIC78_RS20905	COG0508	dehydrogenase complex catalyzes the overall conversion of
DIC78_RS20910	COG0385	Bile acid
DIC78_RS20915	COG0733	neurotransmitter:sodium symporter activity
DIC78_RS20920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DIC78_RS20925	COG1657	PFAM Prenyltransferase squalene oxidase
DIC78_RS20930	COG1012	belongs to the aldehyde dehydrogenase family
DIC78_RS20945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DIC78_RS20950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DIC78_RS20960	COG0514	ATP-dependent DNA helicase (RecQ)
DIC78_RS20965	COG3584	3D domain protein
DIC78_RS20965	COG1388	LysM domain
DIC78_RS20975	COG2197	response regulator
DIC78_RS20980	COG4585	Histidine kinase
DIC78_RS20985	COG3239	Fatty acid desaturase
DIC78_RS20990	COG1619	proteins homologs of microcin C7 resistance protein MccF
DIC78_RS21005	COG2322	membrane
DIC78_RS21010	COG0741	lytic transglycosylase activity
DIC78_RS21015	COG0640	Transcriptional regulator
DIC78_RS21025	COG2378	regulation of single-species biofilm formation
DIC78_RS21030	COG3708	Transcriptional regulator
DIC78_RS21035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DIC78_RS21040	COG1309	transcriptional regulator
DIC78_RS21045	COG0456	acetyltransferase
DIC78_RS21050	COG2207	Transcriptional regulator
DIC78_RS21050	COG0662	Cupin 2, conserved barrel domain protein
DIC78_RS21055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DIC78_RS21065	COG1733	regulation of RNA biosynthetic process
DIC78_RS21070	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS21085	COG3848	Pyruvate phosphate dikinase
DIC78_RS21085	COG0574	Belongs to the PEP-utilizing enzyme family
DIC78_RS21095	COG0457	Tetratricopeptide repeat
DIC78_RS21190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DIC78_RS21200	COG2318	DinB family
DIC78_RS21205	COG3397	chitin binding
DIC78_RS21230	COG2211	Major facilitator Superfamily
DIC78_RS21235	COG3507	Belongs to the glycosyl hydrolase 43 family
DIC78_RS21250	COG1070	Carbohydrate kinase
DIC78_RS21260	COG1231	oxidoreductase activity
DIC78_RS21265	COG1525	nuclease
DIC78_RS21270	COG2814	Major facilitator Superfamily
DIC78_RS21305	COG1028	Short-chain dehydrogenase reductase Sdr
DIC78_RS21315	COG3619	membrane
DIC78_RS21320	COG4305	rare lipoprotein A
DIC78_RS21325	COG1609	Transcriptional regulator
DIC78_RS21330	COG1082	Xylose isomerase domain protein TIM barrel
DIC78_RS21335	COG0673	inositol 2-dehydrogenase activity
DIC78_RS21350	COG0243	molybdopterin cofactor binding
DIC78_RS21355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DIC78_RS21360	COG1070	Carbohydrate kinase
DIC78_RS21365	COG2814	Major facilitator Superfamily
DIC78_RS21380	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DIC78_RS21385	COG0300	oxidoreductase activity
DIC78_RS21405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DIC78_RS21410	COG0583	DNA-binding transcription factor activity
DIC78_RS21415	COG0070	glutamate synthase
DIC78_RS21415	COG0069	glutamate synthase activity
DIC78_RS21415	COG0067	glutamate synthase
DIC78_RS21420	COG0493	'glutamate synthase
DIC78_RS21425	COG0604	alcohol dehydrogenase
DIC78_RS21430	COG0583	DNA-binding transcription factor activity
DIC78_RS21435	COG0405	Gamma-glutamyltransferase
DIC78_RS21440	COG0166	Belongs to the GPI family
DIC78_RS21445	COG0582	viral genome integration into host DNA
DIC78_RS21460	COG0534	Mate efflux family protein
DIC78_RS21470	COG2017	converts alpha-aldose to the beta-anomer
DIC78_RS21475	COG2027	D-alanyl-D-alanine carboxypeptidase
DIC78_RS21480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS21485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DIC78_RS21490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity