locus-tag	class	description
OP701_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OP701_RS00010	COG0592	DNA-directed DNA polymerase activity
OP701_RS00015	COG2501	S4 domain
OP701_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OP701_RS00030	COG0187	DNA topoisomerase II activity
OP701_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OP701_RS00070	COG0516	GMP reductase activity
OP701_RS00070	COG0517	IMP dehydrogenase activity
OP701_RS00075	COG1686	Belongs to the peptidase S11 family
OP701_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OP701_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OP701_RS00100	COG1428	Deoxynucleoside kinase
OP701_RS00105	COG1428	Deoxynucleoside kinase
OP701_RS00110	COG1388	LysM domain
OP701_RS00110	COG3858	chitin binding
OP701_RS00115	COG1335	isochorismatase
OP701_RS00120	COG0590	tRNA wobble adenosine to inosine editing
OP701_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OP701_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OP701_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OP701_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OP701_RS00190	COG3853	Toxic anion resistance protein (TelA)
OP701_RS00195	COG1982	Orn Lys Arg decarboxylase major
OP701_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OP701_RS00205	COG3870	Protein conserved in bacteria
OP701_RS00210	COG1728	Protein conserved in bacteria
OP701_RS00215	COG0470	DNA polymerase III
OP701_RS00220	COG1774	PSP1 C-terminal conserved region
OP701_RS00225	COG4467	Involved in initiation control of chromosome replication
OP701_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OP701_RS00235	COG2827	Endonuclease containing a URI domain
OP701_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OP701_RS00245	COG2002	toxin-antitoxin pair type II binding
OP701_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP701_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP701_RS00255	COG0084	hydrolase, TatD family'
OP701_RS00260	COG3583	domain protein
OP701_RS00260	COG3584	3D domain protein
OP701_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OP701_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OP701_RS00280	COG4466	Protein conserved in bacteria
OP701_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OP701_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OP701_RS00300	COG0251	oxidation-reduction process
OP701_RS00305	COG2088	sporulation resulting in formation of a cellular spore
OP701_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OP701_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OP701_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OP701_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
OP701_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OP701_RS00340	COG2002	toxin-antitoxin pair type II binding
OP701_RS00345	COG2244	polysaccharide biosynthetic process
OP701_RS00350	COG3956	TIGRFAM MazG family protein
OP701_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OP701_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OP701_RS00375	COG1098	S1 RNA binding domain
OP701_RS00390	COG2208	phosphoserine phosphatase activity
OP701_RS00395	COG2304	oxidoreductase activity
OP701_RS00400	COG0515	serine threonine protein kinase
OP701_RS00405	COG0037	tRNA processing
OP701_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OP701_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OP701_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OP701_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OP701_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OP701_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OP701_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OP701_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
OP701_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OP701_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OP701_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OP701_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OP701_RS00470	COG1396	sequence-specific DNA binding
OP701_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OP701_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OP701_RS00560	COG4463	regulation of RNA biosynthetic process
OP701_RS00565	COG3880	PFAM UvrB UvrC protein
OP701_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OP701_RS00575	COG0542	response to heat
OP701_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OP701_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OP701_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
OP701_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OP701_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OP701_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OP701_RS00610	COG1045	serine acetyltransferase
OP701_RS00615	COG0215	cysteine-tRNA ligase activity
OP701_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OP701_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OP701_RS00630	COG3688	RNA-binding protein containing a PIN domain
OP701_RS00635	COG1595	DNA-templated transcription, initiation
OP701_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OP701_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
OP701_RS00660	COG0081	regulation of translation
OP701_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OP701_RS00675	COG2813	Specifically methylates the guanine in position
OP701_RS00680	COG0085	RNA polymerase activity
OP701_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OP701_RS00690	COG1358	cellular component organization or biogenesis
OP701_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OP701_RS00700	COG0049	tRNA binding
OP701_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OP701_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OP701_RS00715	COG0596	Alpha beta hydrolase
OP701_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OP701_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OP701_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OP701_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OP701_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OP701_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OP701_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OP701_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OP701_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OP701_RS00820	COG0200	Binds to the 23S rRNA
OP701_RS00825	COG0201	protein transport
OP701_RS00830	COG0563	adenylate kinase activity
OP701_RS00835	COG0024	Methionine aminopeptidase
OP701_RS00845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OP701_RS00850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OP701_RS00855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OP701_RS00860	COG0202	RNA polymerase activity
OP701_RS00865	COG0203	ribosomal protein L17
OP701_RS00870	COG1122	ATPase activity
OP701_RS00875	COG1122	ATPase activity
OP701_RS00880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OP701_RS00885	COG0101	tRNA pseudouridine synthase activity
OP701_RS00890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OP701_RS00895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OP701_RS00900	COG2226	methyltransferase
OP701_RS00910	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP701_RS00915	COG0489	protein tyrosine kinase activity
OP701_RS00925	COG2194	sulfuric ester hydrolase activity
OP701_RS00930	COG0726	polysaccharide deacetylase
OP701_RS01010	COG0738	Major facilitator superfamily
OP701_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OP701_RS01025	COG1063	alcohol dehydrogenase
OP701_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
OP701_RS01035	COG0385	Bile acid
OP701_RS01040	COG2819	hydrolase of the alpha beta superfamily
OP701_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP701_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP701_RS01060	COG2207	Transcriptional regulator
OP701_RS01065	COG3876	Protein conserved in bacteria
OP701_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
OP701_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OP701_RS01080	COG1263	PTS System
OP701_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS01085	COG1737	Transcriptional regulator
OP701_RS01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OP701_RS01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS01100	COG1683	Conserved Protein
OP701_RS01130	COG1595	DNA-templated transcription, initiation
OP701_RS01135	COG5662	AntiSigma factor
OP701_RS01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OP701_RS01145	COG4856	YbbR-like protein
OP701_RS01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OP701_RS01160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OP701_RS01165	COG3002	Belongs to the UPF0753 family
OP701_RS01170	COG0288	reversible hydration of carbon dioxide
OP701_RS01180	COG5609	conserved protein (DUF2294)
OP701_RS01185	COG0640	Transcriptional regulator
OP701_RS01190	COG2814	Major facilitator Superfamily
OP701_RS01195	COG1413	lyase activity
OP701_RS01205	COG0789	Transcriptional regulator
OP701_RS01210	COG0596	Alpha beta hydrolase
OP701_RS01215	COG0745	RESPONSE REGULATOR receiver
OP701_RS01220	COG0642	Histidine kinase
OP701_RS01230	COG0515	serine threonine protein kinase
OP701_RS01245	COG1113	amino acid transport
OP701_RS01260	COG2602	Beta-lactamase
OP701_RS01265	COG2124	cytochrome p450
OP701_RS01275	COG0531	amino acid
OP701_RS01280	COG1283	sodium-dependent phosphate transmembrane transporter activity
OP701_RS01285	COG0584	glycerophosphoryl diester phosphodiesterase
OP701_RS01290	COG2271	Major facilitator Superfamily
OP701_RS01300	COG0456	acetyltransferase
OP701_RS01300	COG1846	Transcriptional regulator
OP701_RS01305	COG2271	Major facilitator Superfamily
OP701_RS01320	COG0697	spore germination
OP701_RS01325	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS01325	COG2207	Transcriptional regulator
OP701_RS01330	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OP701_RS01335	COG3591	Belongs to the peptidase S1B family
OP701_RS01345	COG0596	Alpha beta hydrolase
OP701_RS01350	COG1183	phosphatidylcholine synthase activity
OP701_RS01355	COG0586	Pfam SNARE associated Golgi protein
OP701_RS01360	COG0688	phosphatidylethanolamine metabolic process
OP701_RS01370	COG2312	Erythromycin esterase
OP701_RS01375	COG2207	Transcriptional regulator
OP701_RS01380	COG1054	Belongs to the UPF0176 family
OP701_RS01385	COG1301	dicarboxylic acid transport
OP701_RS01390	COG2190	(PTS) system
OP701_RS01390	COG1263	PTS System
OP701_RS01390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS01395	COG0363	glucosamine-6-phosphate deaminase activity
OP701_RS01400	COG2188	Transcriptional regulator
OP701_RS01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OP701_RS01415	COG0833	amino acid
OP701_RS01420	COG2040	homocysteine
OP701_RS01425	COG1115	amino acid carrier protein
OP701_RS01430	COG2066	Belongs to the glutaminase family
OP701_RS01435	COG4191	Histidine kinase
OP701_RS01440	COG0784	Response regulator, receiver
OP701_RS01445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OP701_RS01450	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS01455	COG2271	Major facilitator Superfamily
OP701_RS01460	COG4948	Mandelate Racemase Muconate Lactonizing
OP701_RS01465	COG2186	Transcriptional regulator
OP701_RS01470	COG2721	sulfolactate sulfo-lyase activity
OP701_RS01475	COG3173	Aminoglycoside phosphotransferase
OP701_RS01485	COG0697	spore germination
OP701_RS01490	COG0745	RESPONSE REGULATOR receiver
OP701_RS01495	COG2205	protein histidine kinase activity
OP701_RS01500	COG1131	(ABC) transporter
OP701_RS01525	COG3773	Cell wall hydrolase
OP701_RS01530	COG2304	oxidoreductase activity
OP701_RS01540	COG3540	Alkaline phosphatase
OP701_RS01545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OP701_RS01550	COG0805	protein transport
OP701_RS01555	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OP701_RS01560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OP701_RS01565	COG0477	Major facilitator Superfamily
OP701_RS01570	COG1309	transcriptional regulator
OP701_RS01575	COG0252	asparaginase activity
OP701_RS01580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OP701_RS01585	COG1714	RDD family
OP701_RS01590	COG1405	negative regulation of cell septum assembly
OP701_RS01590	COG3012	SEC-C Motif Domain Protein
OP701_RS01595	COG3290	protein histidine kinase activity
OP701_RS01600	COG3279	Response regulator of the LytR AlgR family
OP701_RS01605	COG4555	ABC transporter
OP701_RS01610	COG1668	transmembrane transport
OP701_RS01615	COG0667	Aldo Keto reductase
OP701_RS01630	COG1595	DNA-templated transcription, initiation
OP701_RS01635	COG1595	DNA-templated transcription, initiation
OP701_RS01645	COG0457	Tetratricopeptide repeat
OP701_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS01655	COG0366	Alpha amylase catalytic
OP701_RS01660	COG0803	Belongs to the bacterial solute-binding protein 9 family
OP701_RS01665	COG1121	(ABC) transporter
OP701_RS01670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP701_RS01675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS01680	COG2310	stress, protein
OP701_RS01685	COG2310	stress, protein
OP701_RS01690	COG2310	stress, protein
OP701_RS01695	COG0861	Integral membrane protein TerC family
OP701_RS01705	COG3853	Toxic anion resistance protein (TelA)
OP701_RS01710	COG0477	Major facilitator Superfamily
OP701_RS01715	COG2814	Major facilitator Superfamily
OP701_RS01720	COG0640	Transcriptional regulator
OP701_RS01725	COG4175	Glycine betaine
OP701_RS01725	COG0517	IMP dehydrogenase activity
OP701_RS01730	COG4176	ABC-type proline glycine betaine transport system permease component
OP701_RS01735	COG2113	Glycine betaine
OP701_RS01740	COG1473	amidohydrolase
OP701_RS01745	COG1288	antiporter activity
OP701_RS01755	COG0366	Alpha amylase catalytic
OP701_RS01760	COG0039	L-malate dehydrogenase activity
OP701_RS01765	COG1620	l-lactate permease
OP701_RS01770	COG2814	Major facilitator Superfamily
OP701_RS01775	COG1846	Transcriptional regulator
OP701_RS01780	COG1280	lysine exporter protein (LysE YggA)
OP701_RS01785	COG3403	YqcI/YcgG family
OP701_RS01790	COG1113	amino acid transport
OP701_RS01795	COG3665	Urea carboxylase-associated protein
OP701_RS01800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OP701_RS01805	COG1660	Displays ATPase and GTPase activities
OP701_RS01810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OP701_RS01815	COG2226	methyltransferase
OP701_RS01820	COG0583	DNA-binding transcription factor activity
OP701_RS01825	COG3458	cephalosporin-C deacetylase activity
OP701_RS01830	COG3541	Predicted nucleotidyltransferase
OP701_RS01835	COG0506	proline dehydrogenase activity
OP701_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS01845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OP701_RS01850	COG2508	Transcriptional regulator
OP701_RS01855	COG3689	TIGRFAM TIGR03943 family protein
OP701_RS01860	COG0701	Predicted permease
OP701_RS01870	COG0492	ferredoxin-NADP+ reductase activity
OP701_RS01875	COG1587	Uroporphyrinogen-III synthase
OP701_RS01875	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OP701_RS01880	COG2146	nitrite reductase [NAD(P)H] activity
OP701_RS01885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OP701_RS01890	COG0243	molybdopterin cofactor binding
OP701_RS01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OP701_RS01900	COG2223	nitrite transmembrane transporter activity
OP701_RS01905	COG1469	GTP cyclohydrolase I activity
OP701_RS01910	COG1376	ErfK ybiS ycfS ynhG family protein
OP701_RS01920	COG0523	cobalamin synthesis protein
OP701_RS01925	COG0765	amino acid transport
OP701_RS01930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS01940	COG1714	RDD family
OP701_RS01950	COG1846	Transcriptional regulator
OP701_RS01960	COG3842	ATPase activity
OP701_RS01965	COG2723	6-phospho-beta-galactosidase activity
OP701_RS01975	COG3209	COG3209 Rhs family protein
OP701_RS01980	COG0840	transmembrane signaling receptor activity
OP701_RS01980	COG3290	protein histidine kinase activity
OP701_RS01985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OP701_RS01990	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OP701_RS01995	COG1733	regulation of RNA biosynthetic process
OP701_RS02000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS02030	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OP701_RS02035	COG2814	Major facilitator Superfamily
OP701_RS02045	COG0697	spore germination
OP701_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS02060	COG2364	Membrane
OP701_RS02065	COG1126	abc transporter atp-binding protein
OP701_RS02070	COG0765	amino acid transport
OP701_RS02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS02080	COG0583	DNA-binding transcription factor activity
OP701_RS02085	COG0163	prenyltransferase activity
OP701_RS02090	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OP701_RS02105	COG0596	Alpha beta hydrolase
OP701_RS02110	COG3104	oligopeptide transport
OP701_RS02115	COG5434	Belongs to the glycosyl hydrolase 28 family
OP701_RS02125	COG0697	spore germination
OP701_RS02135	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OP701_RS02140	COG1136	(ABC) transporter
OP701_RS02145	COG0577	efflux transmembrane transporter activity
OP701_RS02150	COG0745	RESPONSE REGULATOR receiver
OP701_RS02155	COG5002	protein histidine kinase activity
OP701_RS02155	COG3850	Histidine kinase
OP701_RS02160	COG0457	Tetratricopeptide repeat
OP701_RS02175	COG0527	aspartate kinase activity
OP701_RS02180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS02185	COG4605	iron ion homeostasis
OP701_RS02190	COG4604	ABC transporter, ATP-binding protein
OP701_RS02195	COG4607	ABC-type enterochelin transport system periplasmic component
OP701_RS02200	COG2814	Major facilitator Superfamily
OP701_RS02205	COG1309	transcriptional regulator
OP701_RS02210	COG0778	Nitroreductase
OP701_RS02215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OP701_RS02220	COG0640	Transcriptional regulator
OP701_RS02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS02230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OP701_RS02235	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS02240	COG4975	Glucose uptake
OP701_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS02250	COG4549	nuclear export factor GLE1
OP701_RS02255	COG2372	response to copper ion
OP701_RS02255	COG1276	copper resistance
OP701_RS02260	COG1349	DNA-binding transcription factor activity
OP701_RS02270	COG2213	PTS system mannitol-specific
OP701_RS02275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS02280	COG0246	Mannitol dehydrogenase
OP701_RS02285	COG0473	3-isopropylmalate dehydrogenase activity
OP701_RS02290	COG0412	Dienelactone hydrolase
OP701_RS02295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OP701_RS02305	COG0561	phosphatase activity
OP701_RS02310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OP701_RS02315	COG1914	H( )-stimulated, divalent metal cation uptake system
OP701_RS02320	COG4336	lyase activity
OP701_RS02325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OP701_RS02330	COG1984	allophanate hydrolase subunit 2
OP701_RS02335	COG1414	Transcriptional regulator
OP701_RS02340	COG2755	lipolytic protein G-D-S-L family
OP701_RS02350	COG2329	Antibiotic biosynthesis monooxygenase
OP701_RS02355	COG0768	penicillin binding
OP701_RS02360	COG4989	oxidoreductase activity
OP701_RS02365	COG3711	transcriptional antiterminator
OP701_RS02370	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS02375	COG2226	methyltransferase
OP701_RS02380	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS02385	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS02395	COG3871	stress protein (general stress protein 26)
OP701_RS02405	COG2814	Major facilitator Superfamily
OP701_RS02410	COG1522	sequence-specific DNA binding
OP701_RS02415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OP701_RS02415	COG0551	DNA topoisomerase type I activity
OP701_RS02420	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OP701_RS02425	COG3706	GGDEF domain
OP701_RS02430	COG5298	Protein conserved in bacteria
OP701_RS02435	COG1215	transferase activity, transferring glycosyl groups
OP701_RS02445	COG0531	amino acid
OP701_RS02455	COG0028	Belongs to the TPP enzyme family
OP701_RS02465	COG1914	H( )-stimulated, divalent metal cation uptake system
OP701_RS02470	COG2261	transglycosylase associated protein
OP701_RS02475	COG4876	unkown
OP701_RS02480	COG2217	Heavy metal translocating P-type atpase
OP701_RS02485	COG3729	General stress protein
OP701_RS02490	COG0662	Cupin 2, conserved barrel domain protein
OP701_RS02495	COG2329	Antibiotic biosynthesis monooxygenase
OP701_RS02500	COG3546	catalase activity
OP701_RS02505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OP701_RS02510	COG3290	protein histidine kinase activity
OP701_RS02515	COG4565	transcriptional regulatory protein
OP701_RS02520	COG1301	dicarboxylic acid transport
OP701_RS02525	COG0628	permease
OP701_RS02530	COG1301	dicarboxylic acid transport
OP701_RS02535	COG1131	(ABC) transporter
OP701_RS02540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OP701_RS02550	COG1960	acyl-CoA dehydrogenase activity
OP701_RS02565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OP701_RS02570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS02575	COG1181	Belongs to the D-alanine--D-alanine ligase family
OP701_RS02580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OP701_RS02585	COG0513	Belongs to the DEAD box helicase family
OP701_RS02590	COG3402	PFAM membrane-flanked domain
OP701_RS02595	COG3428	Bacterial PH domain
OP701_RS02600	COG0705	Rhomboid family
OP701_RS02605	COG0736	holo-[acyl-carrier-protein] synthase activity
OP701_RS02610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OP701_RS02615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OP701_RS02620	COG0864	Transcriptional regulator
OP701_RS02625	COG2337	Toxic component of a toxin-antitoxin (TA) module
OP701_RS02630	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS02635	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS02640	COG2172	sigma factor antagonist activity
OP701_RS02645	COG2208	phosphoserine phosphatase activity
OP701_RS02650	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS02655	COG2172	sigma factor antagonist activity
OP701_RS02660	COG1191	sigma factor activity
OP701_RS02665	COG2208	phosphoserine phosphatase activity
OP701_RS02670	COG2183	response to ionizing radiation
OP701_RS02680	COG3091	SprT-like family
OP701_RS02735	COG1846	Transcriptional regulator
OP701_RS02740	COG2070	2-Nitropropane dioxygenase
OP701_RS02745	COG0431	NADPH-dependent FMN reductase
OP701_RS02750	COG4978	Transcriptional regulator
OP701_RS02750	COG0789	Transcriptional regulator
OP701_RS02755	COG0702	epimerase
OP701_RS02760	COG0697	spore germination
OP701_RS02770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS02775	COG0697	spore germination
OP701_RS02795	COG1476	TRANSCRIPTIONal
OP701_RS02820	COG2807	transmembrane transport
OP701_RS02830	COG1278	Cold shock
OP701_RS02835	COG1329	Transcriptional regulator
OP701_RS02840	COG3708	Transcriptional regulator
OP701_RS02840	COG2207	Transcriptional regulator
OP701_RS02855	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OP701_RS02860	COG2814	Major facilitator Superfamily
OP701_RS02875	COG1309	transcriptional regulator
OP701_RS02880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS02885	COG1316	TRANSCRIPTIONal
OP701_RS02900	COG5002	protein histidine kinase activity
OP701_RS02905	COG0745	RESPONSE REGULATOR receiver
OP701_RS02910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS02925	COG1114	Component of the transport system for branched-chain amino acids
OP701_RS02930	COG0583	DNA-binding transcription factor activity
OP701_RS02935	COG0114	fumarate hydratase activity
OP701_RS02940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OP701_RS02945	COG1522	sequence-specific DNA binding
OP701_RS02950	COG0697	spore germination
OP701_RS02955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS02960	COG2030	dehydratase
OP701_RS02965	COG3545	Serine hydrolase
OP701_RS02970	COG1733	regulation of RNA biosynthetic process
OP701_RS02975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS02985	COG0446	pyridine nucleotide-disulphide oxidoreductase
OP701_RS02990	COG0640	Transcriptional regulator
OP701_RS02995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OP701_RS03000	COG0789	Transcriptional regulator
OP701_RS03005	COG0697	spore germination
OP701_RS03010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS03015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OP701_RS03020	COG0640	Transcriptional regulator
OP701_RS03025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OP701_RS03040	COG4585	Histidine kinase
OP701_RS03045	COG2197	response regulator
OP701_RS03050	COG2409	Drug exporters of the RND superfamily
OP701_RS03055	COG1811	Na channel or pump
OP701_RS03060	COG0789	Transcriptional regulator
OP701_RS03060	COG4978	Transcriptional regulator
OP701_RS03065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OP701_RS03070	COG0778	Nitroreductase
OP701_RS03075	COG0346	lactoylglutathione lyase activity
OP701_RS03080	COG2259	Doxx family
OP701_RS03085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS03090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS03100	COG1309	transcriptional regulator
OP701_RS03110	COG0456	acetyltransferase
OP701_RS03120	COG0673	inositol 2-dehydrogenase activity
OP701_RS03125	COG1609	Transcriptional regulator
OP701_RS03130	COG2814	Major facilitator Superfamily
OP701_RS03135	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS03145	COG0488	(ABC) transporter
OP701_RS03150	COG1113	amino acid transport
OP701_RS03155	COG2318	DinB family
OP701_RS03160	COG1846	Transcriptional regulator
OP701_RS03165	COG2409	Drug exporters of the RND superfamily
OP701_RS03165	COG1033	growth of symbiont in host cell
OP701_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS03180	COG0778	Nitroreductase
OP701_RS03185	COG1846	Transcriptional regulator
OP701_RS03190	COG1396	sequence-specific DNA binding
OP701_RS03205	COG2814	Major facilitator Superfamily
OP701_RS03210	COG0730	response to heat
OP701_RS03215	COG1802	Transcriptional regulator
OP701_RS03220	COG1388	LysM domain
OP701_RS03220	COG3858	chitin binding
OP701_RS03225	COG1819	glycosyl
OP701_RS03235	COG1785	Belongs to the alkaline phosphatase family
OP701_RS03240	COG5646	InterPro IPR014922
OP701_RS03250	COG0454	-acetyltransferase
OP701_RS03255	COG1078	dGTPase activity
OP701_RS03260	COG1388	LysM domain
OP701_RS03265	COG2814	Major facilitator Superfamily
OP701_RS03270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP701_RS03275	COG1447	Phosphotransferase system cellobiose-specific component IIA
OP701_RS03280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP701_RS03285	COG2723	6-phospho-beta-galactosidase activity
OP701_RS03290	COG2188	Transcriptional regulator
OP701_RS03295	COG1940	carbohydrate kinase activity
OP701_RS03300	COG1482	cell wall glycoprotein biosynthetic process
OP701_RS03305	COG4124	Belongs to the glycosyl hydrolase 26 family
OP701_RS03350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OP701_RS03355	COG0802	atpase or kinase
OP701_RS03360	COG1214	PFAM Peptidase M22, glycoprotease
OP701_RS03365	COG0456	acetyltransferase
OP701_RS03370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OP701_RS03375	COG0488	(ABC) transporter
OP701_RS03380	COG0315	cyclic pyranopterin monophosphate synthase activity
OP701_RS03385	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OP701_RS03390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OP701_RS03395	COG0805	protein transport
OP701_RS03405	COG1266	CAAX protease self-immunity
OP701_RS03415	COG0459	protein refolding
OP701_RS03425	COG1073	alpha beta
OP701_RS03430	COG0457	Tetratricopeptide repeat
OP701_RS03435	COG1063	alcohol dehydrogenase
OP701_RS03440	COG2211	Major facilitator Superfamily
OP701_RS03445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP701_RS03455	COG2814	Major facilitator Superfamily
OP701_RS03460	COG1063	alcohol dehydrogenase
OP701_RS03465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OP701_RS03470	COG0823	Involved in the tonB-independent uptake of proteins
OP701_RS03485	COG2267	carboxylic ester hydrolase activity
OP701_RS03495	COG2132	Multicopper oxidase
OP701_RS03500	COG1113	amino acid transport
OP701_RS03505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OP701_RS03510	COG0714	Associated with various cellular activities
OP701_RS03515	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OP701_RS03520	COG1305	Transglutaminase-like
OP701_RS03525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OP701_RS03525	COG0519	Catalyzes the synthesis of GMP from XMP
OP701_RS03540	COG2252	PERMEase
OP701_RS03545	COG3064	Membrane
OP701_RS03555	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OP701_RS03565	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OP701_RS03570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OP701_RS03575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OP701_RS03580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OP701_RS03585	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OP701_RS03590	COG0047	phosphoribosylformylglycinamidine synthase activity
OP701_RS03595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OP701_RS03600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OP701_RS03605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OP701_RS03610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OP701_RS03615	COG0138	bifunctional purine biosynthesis protein purh
OP701_RS03620	COG0151	Belongs to the GarS family
OP701_RS03625	COG1522	sequence-specific DNA binding
OP701_RS03630	COG0531	amino acid
OP701_RS03640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OP701_RS03645	COG1470	cell adhesion involved in biofilm formation
OP701_RS03650	COG4496	protein, YerC YecD
OP701_RS03655	COG0069	glutamate synthase activity
OP701_RS03660	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OP701_RS03665	COG0210	DNA helicase
OP701_RS03670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OP701_RS03675	COG4851	CamS sex pheromone cAM373 precursor
OP701_RS03680	COG2814	Major facilitator Superfamily
OP701_RS03700	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OP701_RS03705	COG1250	3-hydroxyacyl-CoA dehydrogenase
OP701_RS03720	COG1960	acyl-CoA dehydrogenase activity
OP701_RS03750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OP701_RS03755	COG1785	Belongs to the alkaline phosphatase family
OP701_RS03760	COG1285	pathogenesis
OP701_RS03765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OP701_RS03770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OP701_RS03775	COG0154	amidase activity
OP701_RS03780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OP701_RS03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP701_RS03795	COG1597	lipid kinase activity
OP701_RS03800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OP701_RS03855	COG3391	amine dehydrogenase activity
OP701_RS03865	COG0457	Tetratricopeptide repeat
OP701_RS03875	COG0217	transcriptional regulatory protein
OP701_RS03885	COG1309	transcriptional regulator
OP701_RS03890	COG3631	Ketosteroid isomerase-related protein
OP701_RS03910	COG3546	catalase activity
OP701_RS03915	COG0454	-acetyltransferase
OP701_RS03925	COG5578	integral membrane protein
OP701_RS03930	COG2972	Histidine kinase
OP701_RS03935	COG4753	response regulator
OP701_RS03935	COG2207	Transcriptional regulator
OP701_RS03940	COG1653	transport
OP701_RS03945	COG1175	transmembrane transport
OP701_RS03950	COG0395	ABC-type sugar transport system, permease component
OP701_RS03955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OP701_RS03960	COG2207	Transcriptional regulator
OP701_RS03965	COG2755	lipolytic protein G-D-S-L family
OP701_RS03975	COG5578	integral membrane protein
OP701_RS03980	COG3401	FG-GAP repeat protein
OP701_RS03985	COG3401	FG-GAP repeat protein
OP701_RS03990	COG2755	lipolytic protein G-D-S-L family
OP701_RS03995	COG1874	Beta-galactosidase
OP701_RS04005	COG1653	transport
OP701_RS04010	COG4209	transmembrane transport
OP701_RS04015	COG0395	ABC-type sugar transport system, permease component
OP701_RS04020	COG1486	melibiose metabolic process
OP701_RS04025	COG2323	membrane
OP701_RS04030	COG2329	Antibiotic biosynthesis monooxygenase
OP701_RS04035	COG0346	lactoylglutathione lyase activity
OP701_RS04045	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS04050	COG5583	Uncharacterized small protein (DUF2292)
OP701_RS04055	COG0670	Belongs to the BI1 family
OP701_RS04060	COG0697	spore germination
OP701_RS04065	COG1846	Transcriptional regulator
OP701_RS04070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OP701_RS04085	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OP701_RS04085	COG2124	cytochrome p450
OP701_RS04090	COG1368	sulfuric ester hydrolase activity
OP701_RS04095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OP701_RS04100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS04105	COG1442	glycosyl transferase family 8
OP701_RS04110	COG1216	Glycosyl transferase, family 2
OP701_RS04115	COG1442	glycosyl transferase family 8
OP701_RS04120	COG2223	nitrite transmembrane transporter activity
OP701_RS04125	COG1011	Hydrolase
OP701_RS04130	COG0531	amino acid
OP701_RS04135	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS04140	COG0840	transmembrane signaling receptor activity
OP701_RS04145	COG0488	(ABC) transporter
OP701_RS04155	COG0789	Transcriptional regulator
OP701_RS04160	COG2814	Major facilitator Superfamily
OP701_RS04165	COG0488	(ABC) transporter
OP701_RS04170	COG0513	Belongs to the DEAD box helicase family
OP701_RS04175	COG0456	acetyltransferase
OP701_RS04180	COG2130	NADP-dependent
OP701_RS04185	COG1120	ATPase activity
OP701_RS04190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS04195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS04200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OP701_RS04215	COG3866	Pectate lyase
OP701_RS04220	COG0471	metal ion transport
OP701_RS04225	COG3290	protein histidine kinase activity
OP701_RS04230	COG4565	transcriptional regulatory protein
OP701_RS04235	COG3181	Tripartite tricarboxylate transporter family receptor
OP701_RS04240	COG2851	Citrate transporter
OP701_RS04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS04250	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OP701_RS04255	COG1254	Belongs to the acylphosphatase family
OP701_RS04260	COG2258	MOSC domain
OP701_RS04280	COG0024	Methionine aminopeptidase
OP701_RS04285	COG1263	PTS System
OP701_RS04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS04290	COG1368	sulfuric ester hydrolase activity
OP701_RS04300	COG1115	amino acid carrier protein
OP701_RS04315	COG1263	PTS System
OP701_RS04315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS04320	COG0366	Alpha amylase catalytic
OP701_RS04325	COG2188	Transcriptional regulator
OP701_RS04330	COG0778	Nitroreductase
OP701_RS04340	COG0693	protein deglycase activity
OP701_RS04345	COG2814	Major facilitator Superfamily
OP701_RS04350	COG4840	Belongs to the UPF0435 family
OP701_RS04355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OP701_RS04360	COG4980	gas vesicle protein
OP701_RS04365	COG1295	ribonuclease BN
OP701_RS04370	COG0477	Major facilitator Superfamily
OP701_RS04375	COG0387	Pfam Sodium calcium exchanger
OP701_RS04385	COG0668	transmembrane transport
OP701_RS04390	COG0535	radical SAM domain protein
OP701_RS04400	COG0726	polysaccharide deacetylase
OP701_RS04405	COG2084	Dehydrogenase
OP701_RS04410	COG0598	Magnesium transport protein CorA
OP701_RS04415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OP701_RS04420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OP701_RS04425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OP701_RS04435	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OP701_RS04445	COG4637	Psort location Cytoplasmic, score
OP701_RS04455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OP701_RS04460	COG0022	dehydrogenase e1 component
OP701_RS04465	COG0508	dehydrogenase complex catalyzes the overall conversion of
OP701_RS04470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP701_RS04475	COG3284	Transcriptional regulator
OP701_RS04485	COG1742	UPF0060 membrane protein
OP701_RS04505	COG4842	Belongs to the WXG100 family
OP701_RS04510	COG1486	melibiose metabolic process
OP701_RS04515	COG1737	Transcriptional regulator
OP701_RS04520	COG1263	PTS System
OP701_RS04520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS04525	COG1132	(ABC) transporter
OP701_RS04530	COG1132	(ABC) transporter
OP701_RS04535	COG2259	Doxx family
OP701_RS04540	COG2514	catechol 2,3-dioxygenase activity
OP701_RS04545	COG4977	sequence-specific DNA binding
OP701_RS04545	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS04550	COG2814	Major facilitator Superfamily
OP701_RS04555	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS04560	COG0673	inositol 2-dehydrogenase activity
OP701_RS04565	COG4585	Histidine kinase
OP701_RS04570	COG2197	response regulator
OP701_RS04575	COG1131	(ABC) transporter
OP701_RS04580	COG0842	Transport permease protein
OP701_RS04580	COG1511	domain protein
OP701_RS04585	COG0842	Transport permease protein
OP701_RS04595	COG1695	Transcriptional regulator
OP701_RS04600	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OP701_RS04620	COG1131	(ABC) transporter
OP701_RS04625	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OP701_RS04630	COG2318	DinB family
OP701_RS04635	COG2814	Major facilitator Superfamily
OP701_RS04640	COG1846	Transcriptional regulator
OP701_RS04645	COG0392	lysyltransferase activity
OP701_RS04645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OP701_RS04650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP701_RS04655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS04660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS04665	COG0384	phenazine biosynthesis protein PhzF
OP701_RS04670	COG0778	Nitroreductase
OP701_RS04685	COG1090	epimerase
OP701_RS04690	COG2137	regulation of response to DNA damage stimulus
OP701_RS04700	COG2814	Major facilitator Superfamily
OP701_RS04715	COG3103	Sh3 type 3 domain protein
OP701_RS04720	COG5658	integral membrane protein
OP701_RS04725	COG0596	Alpha beta hydrolase
OP701_RS04730	COG0463	Glycosyl transferase, family 2
OP701_RS04735	COG4485	Bacterial membrane protein, YfhO
OP701_RS04740	COG1988	membrane-bound metal-dependent
OP701_RS04745	COG1194	a g-specific adenine glycosylase
OP701_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04770	COG3557	Belongs to the UPF0374 family
OP701_RS04775	COG1132	(ABC) transporter
OP701_RS04780	COG4129	membrane
OP701_RS04785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OP701_RS04790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OP701_RS04795	COG0735	belongs to the Fur family
OP701_RS04915	COG0534	Mate efflux family protein
OP701_RS04920	COG2226	methyltransferase
OP701_RS04930	COG2070	2-Nitropropane dioxygenase
OP701_RS04930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OP701_RS04935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS04940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS04950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS04950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04950	COG3321	synthase
OP701_RS04950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS04960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS04960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS04960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS04960	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04960	COG3321	synthase
OP701_RS04965	COG3321	synthase
OP701_RS04965	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS04965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS04965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS04975	COG3321	synthase
OP701_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS04975	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS04975	COG0300	oxidoreductase activity
OP701_RS04980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS04980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS04980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04980	COG3321	synthase
OP701_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS04985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS04985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS04985	COG3321	synthase
OP701_RS04985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS04990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OP701_RS04995	COG3425	synthase
OP701_RS05000	COG1024	Enoyl-CoA hydratase
OP701_RS05005	COG1024	Enoyl-CoA hydratase
OP701_RS05010	COG1024	Enoyl-CoA hydratase
OP701_RS05015	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS05020	COG1819	glycosyl
OP701_RS05050	COG4326	sporulation control protein
OP701_RS05060	COG5577	PFAM Coat F domain
OP701_RS05065	COG3340	Belongs to the peptidase S51 family
OP701_RS05070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OP701_RS05080	COG0753	catalase activity
OP701_RS05085	COG1116	anion transmembrane transporter activity
OP701_RS05090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OP701_RS05095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OP701_RS05100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS05110	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OP701_RS05120	COG1476	TRANSCRIPTIONal
OP701_RS05130	COG3382	B3 4 domain protein
OP701_RS05135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OP701_RS05145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OP701_RS05150	COG0789	Transcriptional regulator
OP701_RS05155	COG1664	Polymer-forming cytoskeletal
OP701_RS05160	COG1664	Polymer-forming cytoskeletal
OP701_RS05165	COG2766	serine protein kinase
OP701_RS05170	COG2718	Belongs to the UPF0229 family
OP701_RS05175	COG1846	Transcriptional regulator
OP701_RS05180	COG1566	PFAM secretion protein HlyD family protein
OP701_RS05185	COG2814	Major facilitator Superfamily
OP701_RS05190	COG0655	NAD(P)H dehydrogenase (quinone) activity
OP701_RS05205	COG1725	Transcriptional regulator
OP701_RS05210	COG1131	(ABC) transporter
OP701_RS05215	COG1131	(ABC) transporter
OP701_RS05220	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OP701_RS05225	COG1278	Cold shock
OP701_RS05230	COG1464	Belongs to the NlpA lipoprotein family
OP701_RS05235	COG3706	GGDEF domain
OP701_RS05240	COG1823	symporter activity
OP701_RS05245	COG0456	acetyltransferase
OP701_RS05255	COG1396	sequence-specific DNA binding
OP701_RS05275	COG5577	PFAM Coat F domain
OP701_RS05280	COG0737	Belongs to the 5'-nucleotidase family
OP701_RS05280	COG4085	toxin activity
OP701_RS05280	COG1525	nuclease
OP701_RS05285	COG3764	Sortase (surface protein transpeptidase)
OP701_RS05290	COG0564	pseudouridine synthase activity
OP701_RS05300	COG0517	IMP dehydrogenase activity
OP701_RS05305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OP701_RS05310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OP701_RS05310	COG3153	acetyltransferase
OP701_RS05320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OP701_RS05325	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OP701_RS05330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OP701_RS05335	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OP701_RS05340	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OP701_RS05345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OP701_RS05350	COG4585	Histidine kinase
OP701_RS05350	COG2203	Gaf domain
OP701_RS05355	COG2197	response regulator
OP701_RS05360	COG0431	NADPH-dependent FMN reductase
OP701_RS05375	COG0791	NLP P60 protein
OP701_RS05375	COG1388	LysM domain
OP701_RS05380	COG1959	2 iron, 2 sulfur cluster binding
OP701_RS05390	COG2719	SpoVR family
OP701_RS05395	COG1785	Belongs to the alkaline phosphatase family
OP701_RS05400	COG0791	NLP P60 protein
OP701_RS05400	COG1388	LysM domain
OP701_RS05405	COG0583	DNA-binding transcription factor activity
OP701_RS05410	COG0372	Belongs to the citrate synthase family
OP701_RS05415	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS05420	COG0531	amino acid
OP701_RS05425	COG0733	neurotransmitter:sodium symporter activity
OP701_RS05430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS05435	COG0456	acetyltransferase
OP701_RS05450	COG1595	DNA-templated transcription, initiation
OP701_RS05455	COG0667	Aldo Keto reductase
OP701_RS05460	COG0204	Acyl-transferase
OP701_RS05465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OP701_RS05475	COG1253	flavin adenine dinucleotide binding
OP701_RS05480	COG0789	Transcriptional regulator
OP701_RS05485	COG0436	Aminotransferase
OP701_RS05490	COG1253	flavin adenine dinucleotide binding
OP701_RS05495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OP701_RS05500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OP701_RS05505	COG0584	glycerophosphoryl diester phosphodiesterase
OP701_RS05515	COG0668	transmembrane transport
OP701_RS05520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OP701_RS05525	COG0726	polysaccharide deacetylase
OP701_RS05530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OP701_RS05535	COG1757	Na H antiporter
OP701_RS05540	COG0589	response to stress
OP701_RS05550	COG1132	(ABC) transporter
OP701_RS05555	COG1132	(ABC) transporter
OP701_RS05560	COG0702	epimerase
OP701_RS05580	COG0189	ligase activity
OP701_RS05585	COG0189	ligase activity
OP701_RS05590	COG4399	Belongs to the UPF0754 family
OP701_RS05595	COG3679	Belongs to the UPF0342 family
OP701_RS05600	COG4335	DNA alkylation repair
OP701_RS05605	COG0561	phosphatase activity
OP701_RS05610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OP701_RS05615	COG0475	glutathione-regulated potassium exporter activity
OP701_RS05620	COG0490	domain, Protein
OP701_RS05630	COG1024	Enoyl-CoA hydratase
OP701_RS05640	COG4152	abc transporter atp-binding protein
OP701_RS05645	COG1668	transmembrane transport
OP701_RS05650	COG0420	3'-5' exonuclease activity
OP701_RS05655	COG4717	serine-type aminopeptidase activity
OP701_RS05660	COG3481	metal-dependent phosphohydrolase, HD sub domain
OP701_RS05670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OP701_RS05695	COG1846	Transcriptional regulator
OP701_RS05700	COG4980	gas vesicle protein
OP701_RS05715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OP701_RS05720	COG0537	adenosine 5'-monophosphoramidase activity
OP701_RS05725	COG1131	(ABC) transporter
OP701_RS05730	COG4473	ABC transporter
OP701_RS05740	COG1473	amidohydrolase
OP701_RS05745	COG3069	C4-dicarboxylate transmembrane transporter activity
OP701_RS05755	COG2329	Antibiotic biosynthesis monooxygenase
OP701_RS05760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OP701_RS05765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OP701_RS05770	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OP701_RS05775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OP701_RS05780	COG1309	transcriptional regulator
OP701_RS05785	COG1511	domain protein
OP701_RS05790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OP701_RS05795	COG4377	Putative membrane peptidase family (DUF2324)
OP701_RS05805	COG1363	Peptidase, m42
OP701_RS05810	COG4405	Protein conserved in bacteria
OP701_RS05815	COG1301	dicarboxylic acid transport
OP701_RS05825	COG1234	tRNA 3'-trailer cleavage
OP701_RS05830	COG0095	Lipoate-protein ligase
OP701_RS05835	COG0702	epimerase
OP701_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS05850	COG0501	Belongs to the peptidase M48B family
OP701_RS05855	COG1404	Belongs to the peptidase S8 family
OP701_RS05860	COG0456	acetyltransferase
OP701_RS05865	COG0604	alcohol dehydrogenase
OP701_RS05875	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OP701_RS05880	COG0406	alpha-ribazole phosphatase activity
OP701_RS05885	COG0183	Belongs to the thiolase family
OP701_RS05890	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS05895	COG1268	BioY protein
OP701_RS05900	COG0840	transmembrane signaling receptor activity
OP701_RS05905	COG0723	plastoquinol--plastocyanin reductase activity
OP701_RS05905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OP701_RS05910	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS05920	COG4903	ComK protein
OP701_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS05935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OP701_RS05950	COG0398	Pfam SNARE associated Golgi protein
OP701_RS05955	COG0681	Belongs to the peptidase S26 family
OP701_RS05960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OP701_RS05965	COG1846	Transcriptional regulator
OP701_RS05975	COG3180	Ammonia monooxygenase
OP701_RS05980	COG0477	Major facilitator Superfamily
OP701_RS05980	COG2814	Major facilitator Superfamily
OP701_RS05985	COG4533	DNA binding
OP701_RS05995	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OP701_RS06000	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OP701_RS06005	COG1074	ATP-dependent DNA helicase activity
OP701_RS06010	COG0420	3'-5' exonuclease activity
OP701_RS06015	COG0419	ATPase involved in DNA repair
OP701_RS06020	COG1403	HNH endonuclease
OP701_RS06060	COG5337	Spore coat protein CotH
OP701_RS06065	COG0179	Fumarylacetoacetate (FAA) hydrolase
OP701_RS06075	COG1404	Belongs to the peptidase S8 family
OP701_RS06085	COG0367	asparagine synthase
OP701_RS06095	COG0534	Mate efflux family protein
OP701_RS06100	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS06100	COG2207	Transcriptional regulator
OP701_RS06105	COG1609	Transcriptional regulator
OP701_RS06110	COG0673	inositol 2-dehydrogenase activity
OP701_RS06115	COG2318	DinB family
OP701_RS06120	COG1279	arginine transmembrane transporter activity
OP701_RS06125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS06130	COG1357	PFAM Pentapeptide repeats (8 copies)
OP701_RS06135	COG2267	carboxylic ester hydrolase activity
OP701_RS06140	COG0529	Catalyzes the synthesis of activated sulfate
OP701_RS06145	COG2046	Belongs to the sulfate adenylyltransferase family
OP701_RS06150	COG0175	sulfate reduction
OP701_RS06155	COG2045	Belongs to the ComB family
OP701_RS06160	COG1809	phosphosulfolactate synthase activity
OP701_RS06165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS06170	COG4948	Mandelate Racemase Muconate Lactonizing
OP701_RS06175	COG2814	Major facilitator Superfamily
OP701_RS06180	COG0454	-acetyltransferase
OP701_RS06185	COG2153	protein acetylation
OP701_RS06190	COG0646	methionine synthase
OP701_RS06190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OP701_RS06195	COG1666	GTP binding
OP701_RS06220	COG1695	Transcriptional regulator
OP701_RS06235	COG3227	Zinc metalloprotease (Elastase)
OP701_RS06240	COG1307	EDD domain protein, DegV family
OP701_RS06245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS06265	COG0561	phosphatase activity
OP701_RS06270	COG1073	alpha beta
OP701_RS06275	COG2151	metal-sulfur cluster biosynthetic enzyme
OP701_RS06285	COG0277	FAD linked oxidase domain protein
OP701_RS06290	COG2271	Major facilitator Superfamily
OP701_RS06295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OP701_RS06300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OP701_RS06310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OP701_RS06315	COG0505	Belongs to the CarA family
OP701_RS06320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OP701_RS06325	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OP701_RS06340	COG2267	carboxylic ester hydrolase activity
OP701_RS06350	COG1744	ABC transporter substrate-binding protein PnrA-like
OP701_RS06365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OP701_RS06370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OP701_RS06375	COG5504	Zn-dependent protease
OP701_RS06380	COG0444	Belongs to the ABC transporter superfamily
OP701_RS06385	COG4608	Belongs to the ABC transporter superfamily
OP701_RS06395	COG0601	transmembrane transport
OP701_RS06400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP701_RS06410	COG0180	Tryptophanyl-tRNA synthetase
OP701_RS06415	COG4166	transmembrane transport
OP701_RS06420	COG0601	transmembrane transport
OP701_RS06425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP701_RS06430	COG0444	Belongs to the ABC transporter superfamily
OP701_RS06435	COG4608	Belongs to the ABC transporter superfamily
OP701_RS06440	COG2814	Major facilitator Superfamily
OP701_RS06445	COG0456	acetyltransferase
OP701_RS06450	COG1393	Belongs to the ArsC family
OP701_RS06455	COG0861	Integral membrane protein TerC family
OP701_RS06465	COG4862	establishment of competence for transformation
OP701_RS06470	COG4469	Competence protein
OP701_RS06475	COG1164	Oligoendopeptidase f
OP701_RS06485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OP701_RS06490	COG2346	COG2346, Truncated hemoglobins
OP701_RS06495	COG0741	lytic transglycosylase activity
OP701_RS06500	COG4116	CYTH
OP701_RS06510	COG2357	RelA SpoT domain protein
OP701_RS06515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OP701_RS06520	COG0564	pseudouridine synthase activity
OP701_RS06525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OP701_RS06530	COG0475	glutathione-regulated potassium exporter activity
OP701_RS06530	COG0569	domain protein
OP701_RS06535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OP701_RS06540	COG0352	thiamine-phosphate diphosphorylase activity
OP701_RS06545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OP701_RS06550	COG2104	thiamine diphosphate biosynthetic process
OP701_RS06555	COG2022	thiamine diphosphate biosynthetic process
OP701_RS06560	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OP701_RS06565	COG0351	phosphomethylpyrimidine kinase
OP701_RS06570	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OP701_RS06625	COG0210	DNA helicase
OP701_RS06635	COG2153	protein acetylation
OP701_RS06640	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OP701_RS06645	COG2382	esterase
OP701_RS06650	COG0626	cystathionine gamma-synthase activity
OP701_RS06655	COG0626	cystathionine gamma-synthase activity
OP701_RS06660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS06665	COG5505	Protein of unknown function (DUF819)
OP701_RS06675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OP701_RS06690	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS06700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS06700	COG3711	transcriptional antiterminator
OP701_RS06705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OP701_RS06705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OP701_RS06705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS06710	COG1482	cell wall glycoprotein biosynthetic process
OP701_RS06725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS06735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OP701_RS06755	COG0109	protoheme IX farnesyltransferase activity
OP701_RS06765	COG0726	polysaccharide deacetylase
OP701_RS06780	COG5504	Zn-dependent protease
OP701_RS06785	COG2205	protein histidine kinase activity
OP701_RS06795	COG3383	formate dehydrogenase (NAD+) activity
OP701_RS06800	COG2427	Protein of unknown function (DUF1641)
OP701_RS06810	COG1051	belongs to the nudix hydrolase family
OP701_RS06820	COG2124	cytochrome p450
OP701_RS06825	COG1819	glycosyl
OP701_RS06835	COG1587	Uroporphyrinogen-III synthase
OP701_RS06840	COG0390	transport system, permease component
OP701_RS06845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OP701_RS06850	COG0697	spore germination
OP701_RS06855	COG4297	protein containing double-stranded beta helix domain
OP701_RS06865	COG1252	NADH dehydrogenase
OP701_RS06870	COG1904	glucuronate isomerase
OP701_RS06875	COG2211	Major facilitator Superfamily
OP701_RS06880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OP701_RS06885	COG1063	alcohol dehydrogenase
OP701_RS06890	COG1312	Catalyzes the dehydration of D-mannonate
OP701_RS06895	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS06900	COG2271	Major facilitator Superfamily
OP701_RS06905	COG1609	Transcriptional regulator
OP701_RS06910	COG0246	Mannitol dehydrogenase
OP701_RS06915	COG2721	sulfolactate sulfo-lyase activity
OP701_RS06920	COG0730	response to heat
OP701_RS06925	COG2318	DinB family
OP701_RS06930	COG0457	Tetratricopeptide repeat
OP701_RS06940	COG2350	Protein conserved in bacteria
OP701_RS06945	COG5632	N-Acetylmuramoyl-L-alanine amidase
OP701_RS06945	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS06945	COG1388	LysM domain
OP701_RS06955	COG4195	phage-related replication protein
OP701_RS06960	COG3546	catalase activity
OP701_RS06965	COG2856	Zn peptidase
OP701_RS06970	COG1396	sequence-specific DNA binding
OP701_RS06980	COG1522	sequence-specific DNA binding
OP701_RS06985	COG1484	DNA-dependent DNA replication
OP701_RS07005	COG1595	DNA-templated transcription, initiation
OP701_RS07010	COG5484	DNA packaging
OP701_RS07010	COG3728	DNA packaging
OP701_RS07015	COG1783	phage Terminase large subunit
OP701_RS07020	COG5518	Phage portal protein
OP701_RS07025	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OP701_RS07030	COG4653	Phage capsid family
OP701_RS07080	COG3953	SLT domain
OP701_RS07080	COG5412	phage tail tape measure protein
OP701_RS07085	COG1652	LysM domain
OP701_RS07090	COG4193	domain, Protein
OP701_RS07100	COG3628	GPW Gp25 family protein
OP701_RS07105	COG3299	homolog of phage Mu protein gp47
OP701_RS07110	COG3778	Protein conserved in bacteria
OP701_RS07155	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS07155	COG5632	N-Acetylmuramoyl-L-alanine amidase
OP701_RS07175	COG0306	phosphate transporter
OP701_RS07180	COG1392	Phosphate transport regulator
OP701_RS07185	COG0531	amino acid
OP701_RS07190	COG0346	lactoylglutathione lyase activity
OP701_RS07200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OP701_RS07205	COG0463	Glycosyl transferase, family 2
OP701_RS07210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP701_RS07215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OP701_RS07220	COG2362	D-Aminopeptidase
OP701_RS07225	COG0601	transmembrane transport
OP701_RS07230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP701_RS07235	COG0444	Belongs to the ABC transporter superfamily
OP701_RS07240	COG4166	transmembrane transport
OP701_RS07245	COG1619	proteins homologs of microcin C7 resistance protein MccF
OP701_RS07250	COG4948	Mandelate Racemase Muconate Lactonizing
OP701_RS07255	COG0791	NLP P60 protein
OP701_RS07260	COG4608	Belongs to the ABC transporter superfamily
OP701_RS07265	COG2706	6-phosphogluconolactonase activity
OP701_RS07270	COG1834	amidinotransferase
OP701_RS07275	COG1607	acyl-coa hydrolase
OP701_RS07280	COG1017	nitric oxide dioxygenase activity
OP701_RS07280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OP701_RS07290	COG2323	membrane
OP701_RS07295	COG2318	DinB family
OP701_RS07300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS07305	COG2076	Multidrug Resistance protein
OP701_RS07310	COG2076	Multidrug Resistance protein
OP701_RS07315	COG0788	formyltetrahydrofolate deformylase activity
OP701_RS07320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OP701_RS07325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OP701_RS07330	COG1764	response to oxidative stress
OP701_RS07335	COG1846	Transcriptional regulator
OP701_RS07340	COG1764	response to oxidative stress
OP701_RS07345	COG0463	Glycosyl transferase, family 2
OP701_RS07345	COG0457	Tetratricopeptide repeat
OP701_RS07350	COG0590	tRNA wobble adenosine to inosine editing
OP701_RS07360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OP701_RS07365	COG1404	Belongs to the peptidase S8 family
OP701_RS07370	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS07375	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OP701_RS07380	COG1122	ATPase activity
OP701_RS07385	COG4721	ABC-type cobalt transport system, permease component
OP701_RS07395	COG0745	RESPONSE REGULATOR receiver
OP701_RS07400	COG3850	Histidine kinase
OP701_RS07400	COG5002	protein histidine kinase activity
OP701_RS07405	COG3212	peptidase
OP701_RS07410	COG3212	peptidase
OP701_RS07425	COG2239	Acts as a magnesium transporter
OP701_RS07430	COG0789	Transcriptional regulator
OP701_RS07445	COG1846	Transcriptional regulator
OP701_RS07455	COG0726	polysaccharide deacetylase
OP701_RS07460	COG1408	metallophosphoesterase
OP701_RS07470	COG0463	Glycosyl transferase, family 2
OP701_RS07475	COG1793	dna ligase
OP701_RS07475	COG3285	dna ligase
OP701_RS07480	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OP701_RS07485	COG5001	Diguanylate cyclase
OP701_RS07485	COG3300	MHYT domain
OP701_RS07490	COG0586	Pfam SNARE associated Golgi protein
OP701_RS07495	COG0861	Integral membrane protein TerC family
OP701_RS07500	COG1191	sigma factor activity
OP701_RS07520	COG0501	Belongs to the peptidase M48B family
OP701_RS07525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OP701_RS07540	COG3594	Acyltransferase
OP701_RS07545	COG5002	protein histidine kinase activity
OP701_RS07550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OP701_RS07560	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OP701_RS07565	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OP701_RS07570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OP701_RS07575	COG0436	Aminotransferase
OP701_RS07580	COG1850	ribulose-bisphosphate carboxylase activity
OP701_RS07585	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OP701_RS07590	COG0235	Class ii aldolase
OP701_RS07595	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OP701_RS07600	COG3339	Conserved Protein
OP701_RS07615	COG3852	Histidine kinase
OP701_RS07620	COG1846	Transcriptional regulator
OP701_RS07625	COG1360	Flagellar Motor Protein
OP701_RS07630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OP701_RS07635	COG0542	response to heat
OP701_RS07640	COG3949	Membrane
OP701_RS07645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OP701_RS07650	COG0720	synthase
OP701_RS07655	COG0602	queuosine metabolic process
OP701_RS07660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OP701_RS07665	COG1388	LysM domain
OP701_RS07665	COG4641	Protein conserved in bacteria
OP701_RS07670	COG1388	LysM domain
OP701_RS07675	COG3858	chitin binding
OP701_RS07685	COG4873	Protein conserved in bacteria
OP701_RS07695	COG3773	Cell wall hydrolase
OP701_RS07700	COG2244	polysaccharide biosynthetic process
OP701_RS07705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS07710	COG2217	Heavy metal translocating P-type atpase
OP701_RS07720	COG0006	proline dipeptidase activity
OP701_RS07725	COG1609	Transcriptional regulator
OP701_RS07730	COG3711	transcriptional antiterminator
OP701_RS07735	COG1263	PTS System
OP701_RS07735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS07735	COG2190	(PTS) system
OP701_RS07740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS07745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OP701_RS07755	COG1533	DNA photolyase activity
OP701_RS07760	COG0456	acetyltransferase
OP701_RS07765	COG0840	transmembrane signaling receptor activity
OP701_RS07770	COG2084	Dehydrogenase
OP701_RS07780	COG2340	Cysteine-rich secretory protein family
OP701_RS07785	COG0768	penicillin binding
OP701_RS07790	COG4191	Histidine kinase
OP701_RS07795	COG0436	Aminotransferase
OP701_RS07805	COG0835	chemotaxis
OP701_RS07805	COG0784	Response regulator, receiver
OP701_RS07815	COG2814	Major facilitator Superfamily
OP701_RS07820	COG1376	ErfK ybiS ycfS ynhG family protein
OP701_RS07825	COG1408	metallophosphoesterase
OP701_RS07830	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS07835	COG2200	EAL domain
OP701_RS07845	COG4703	Protein of unknown function (DUF1797)
OP701_RS07850	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OP701_RS07860	COG0517	IMP dehydrogenase activity
OP701_RS07865	COG0583	DNA-binding transcription factor activity
OP701_RS07870	COG0716	FMN binding
OP701_RS07880	COG0716	FMN binding
OP701_RS07885	COG2171	N-acyltransferase activity
OP701_RS07890	COG1473	amidohydrolase
OP701_RS07900	COG0668	transmembrane transport
OP701_RS07905	COG0450	alkyl hydroperoxide reductase
OP701_RS07910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS07925	COG0746	molybdenum cofactor guanylyltransferase activity
OP701_RS07930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OP701_RS07935	COG0303	'Molybdopterin
OP701_RS07940	COG1763	Mo-molybdopterin cofactor biosynthetic process
OP701_RS07945	COG0314	molybdopterin synthase activity
OP701_RS07950	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OP701_RS07955	COG1132	(ABC) transporter
OP701_RS07960	COG1132	(ABC) transporter
OP701_RS07970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP701_RS07975	COG1136	(ABC) transporter
OP701_RS07980	COG0577	efflux transmembrane transporter activity
OP701_RS07985	COG1349	DNA-binding transcription factor activity
OP701_RS07990	COG1105	Belongs to the carbohydrate kinase PfkB family
OP701_RS07995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS07995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OP701_RS07995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OP701_RS08000	COG0681	Belongs to the peptidase S26 family
OP701_RS08010	COG0488	(ABC) transporter
OP701_RS08015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OP701_RS08020	COG2309	aminopeptidase activity
OP701_RS08030	COG1077	Cell shape determining protein MreB Mrl
OP701_RS08035	COG2002	toxin-antitoxin pair type II binding
OP701_RS08040	COG3852	Histidine kinase
OP701_RS08045	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
OP701_RS08045	COG2105	PFAM AIG2 family protein
OP701_RS08050	COG0569	domain protein
OP701_RS08055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OP701_RS08060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OP701_RS08065	COG5503	Protein of unknown function (DUF1447)
OP701_RS08070	COG0561	phosphatase activity
OP701_RS08075	COG0242	peptide deformylase activity
OP701_RS08085	COG0497	DNA recombination
OP701_RS08090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OP701_RS08095	COG0022	dehydrogenase e1 component
OP701_RS08100	COG0508	dehydrogenase complex catalyzes the overall conversion of
OP701_RS08105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP701_RS08110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS08125	COG1982	Orn Lys Arg decarboxylase major
OP701_RS08130	COG4476	Belongs to the UPF0223 family
OP701_RS08135	COG4493	Belongs to the UPF0637 family
OP701_RS08145	COG0483	inositol monophosphate 1-phosphatase activity
OP701_RS08160	COG0657	acetylesterase activity
OP701_RS08165	COG1959	2 iron, 2 sulfur cluster binding
OP701_RS08185	COG1595	DNA-templated transcription, initiation
OP701_RS08205	COG1217	gtp-binding protein TYPA
OP701_RS08215	COG4896	Protein conserved in bacteria
OP701_RS08225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OP701_RS08230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OP701_RS08235	COG2066	Belongs to the glutaminase family
OP701_RS08240	COG4838	Belongs to the UPF0358 family
OP701_RS08245	COG0772	Belongs to the SEDS family
OP701_RS08250	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OP701_RS08255	COG1612	heme a metabolic process
OP701_RS08260	COG0109	protoheme IX farnesyltransferase activity
OP701_RS08265	COG2010	Cytochrome c
OP701_RS08265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OP701_RS08270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OP701_RS08275	COG1845	cytochrome c oxidase, subunit III
OP701_RS08280	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OP701_RS08285	COG3336	cytochrome c oxidase
OP701_RS08295	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OP701_RS08300	COG2340	Cysteine-rich secretory protein family
OP701_RS08315	COG3679	Belongs to the UPF0342 family
OP701_RS08320	COG4471	UPF0298 protein
OP701_RS08325	COG0742	ribosomal rna small subunit methyltransferase
OP701_RS08330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OP701_RS08335	COG3314	Sporulation integral membrane protein YlbJ
OP701_RS08340	COG1752	Esterase of the alpha-beta hydrolase superfamily
OP701_RS08345	COG3480	Lon protease (S16) C-terminal proteolytic domain
OP701_RS08350	COG1323	Belongs to the UPF0348 family
OP701_RS08360	COG1399	metal-binding, possibly nucleic acid-binding protein
OP701_RS08375	COG0454	-acetyltransferase
OP701_RS08380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OP701_RS08385	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OP701_RS08390	COG2001	Belongs to the MraZ family
OP701_RS08395	COG0275	rRNA processing
OP701_RS08400	COG4839	cell division protein FtsL
OP701_RS08405	COG0768	penicillin binding
OP701_RS08410	COG0768	penicillin binding
OP701_RS08415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OP701_RS08420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OP701_RS08425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OP701_RS08430	COG0772	Belongs to the SEDS family
OP701_RS08435	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OP701_RS08440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OP701_RS08445	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OP701_RS08450	COG3879	Bacterial protein of unknown function (DUF881)
OP701_RS08455	COG3879	Bacterial protein of unknown function (DUF881)
OP701_RS08460	COG3856	small basic protein
OP701_RS08465	COG0849	cell division
OP701_RS08470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OP701_RS08475	COG1404	Belongs to the peptidase S8 family
OP701_RS08475	COG4412	M6 family metalloprotease domain protein
OP701_RS08485	COG1191	sigma factor activity
OP701_RS08490	COG1191	sigma factor activity
OP701_RS08495	COG1119	ATPase activity
OP701_RS08500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OP701_RS08505	COG1873	PFAM PRC-barrel domain
OP701_RS08510	COG1496	oxidoreductase activity
OP701_RS08515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OP701_RS08520	COG1799	cell septum assembly
OP701_RS08525	COG0762	integral membrane protein
OP701_RS08530	COG2302	S4 RNA-binding domain
OP701_RS08535	COG3599	regulation of cell shape
OP701_RS08540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OP701_RS08545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OP701_RS08550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OP701_RS08555	COG0564	pseudouridine synthase activity
OP701_RS08560	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OP701_RS08565	COG2233	PERMEase
OP701_RS08570	COG0540	Belongs to the ATCase OTCase family
OP701_RS08575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OP701_RS08580	COG0505	Belongs to the CarA family
OP701_RS08585	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OP701_RS08590	COG0543	2 iron, 2 sulfur cluster binding
OP701_RS08595	COG0167	dihydroorotate dehydrogenase activity
OP701_RS08600	COG0284	orotidine-5'-phosphate decarboxylase activity
OP701_RS08605	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OP701_RS08610	COG0175	sulfate reduction
OP701_RS08615	COG0306	phosphate transporter
OP701_RS08620	COG2046	Belongs to the sulfate adenylyltransferase family
OP701_RS08625	COG0529	Catalyzes the synthesis of activated sulfate
OP701_RS08630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OP701_RS08635	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OP701_RS08640	COG1648	precorrin-2 dehydrogenase activity
OP701_RS08645	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OP701_RS08650	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OP701_RS08655	COG1561	YicC-like family, N-terminal region
OP701_RS08665	COG0194	GDP metabolic process
OP701_RS08670	COG1758	RNA polymerase activity
OP701_RS08675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OP701_RS08680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OP701_RS08685	COG0242	peptide deformylase activity
OP701_RS08690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OP701_RS08695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OP701_RS08695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OP701_RS08700	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OP701_RS08705	COG0631	protein serine/threonine phosphatase activity
OP701_RS08710	COG0515	serine threonine protein kinase
OP701_RS08710	COG2815	serine threonine protein kinase
OP701_RS08715	COG1162	GTPase activity
OP701_RS08720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OP701_RS08725	COG1564	THIamine pyrophosphokinase
OP701_RS08735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OP701_RS08740	COG1302	Protein conserved in bacteria
OP701_RS08745	COG1461	Dihydroxyacetone kinase
OP701_RS08750	COG1760	l-serine dehydratase
OP701_RS08755	COG1760	l-serine dehydratase
OP701_RS08760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OP701_RS08765	COG1349	DNA-binding transcription factor activity
OP701_RS08765	COG2050	protein possibly involved in aromatic compounds catabolism
OP701_RS08770	COG0416	fatty acid biosynthetic process
OP701_RS08775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OP701_RS08780	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS08790	COG0571	ribonuclease III activity
OP701_RS08795	COG1196	nuclear chromosome segregation
OP701_RS08800	COG0552	protein localization to endoplasmic reticulum
OP701_RS08810	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OP701_RS08815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OP701_RS08820	COG0228	four-way junction DNA binding
OP701_RS08825	COG1837	Belongs to the UPF0109 family
OP701_RS08835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OP701_RS08840	COG0336	Belongs to the RNA methyltransferase TrmD family
OP701_RS08845	COG0335	large ribosomal subunit rRNA binding
OP701_RS08850	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OP701_RS08855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OP701_RS08865	COG2257	FlhB HrpN YscU SpaS Family
OP701_RS08870	COG0045	succinate-CoA ligase (ADP-forming) activity
OP701_RS08875	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OP701_RS08880	COG0758	DNA mediated transformation
OP701_RS08885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OP701_RS08890	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OP701_RS08895	COG4974	Belongs to the 'phage' integrase family
OP701_RS08900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OP701_RS08905	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OP701_RS08910	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OP701_RS08915	COG1815	bacterial-type flagellum-dependent cell motility
OP701_RS08920	COG1558	bacterial-type flagellum-dependent cell motility
OP701_RS08925	COG1677	Flagellar hook-basal body complex protein FliE
OP701_RS08930	COG1766	The M ring may be actively involved in energy transduction
OP701_RS08935	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OP701_RS08940	COG1317	bacterial-type flagellum organization
OP701_RS08945	COG1157	protein secretion by the type III secretion system
OP701_RS08950	COG2882	bacterial-type flagellum organization
OP701_RS08955	COG3334	PFAM MgtE intracellular
OP701_RS08960	COG3144	bacterial-type flagellum assembly
OP701_RS08965	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OP701_RS08970	COG4786	Flagellar basal body rod
OP701_RS08975	COG1582	Flagellar protein (FlbD)
OP701_RS08980	COG1580	Controls the rotational direction of flagella during chemotaxis
OP701_RS08985	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OP701_RS08990	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OP701_RS08990	COG1776	CheC inhibitor of MCP methylation
OP701_RS08995	COG2201	protein-glutamate methylesterase activity
OP701_RS09000	COG3190	flagellar
OP701_RS09005	COG1338	Plays a role in the flagellum-specific transport system
OP701_RS09010	COG1987	bacterial-type flagellum assembly
OP701_RS09020	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OP701_RS09025	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OP701_RS09030	COG1419	protein localization to endoplasmic reticulum
OP701_RS09035	COG0455	bacterial-type flagellum organization
OP701_RS09040	COG2201	protein-glutamate methylesterase activity
OP701_RS09045	COG0643	Histidine kinase
OP701_RS09045	COG2198	Histidine kinase
OP701_RS09050	COG0835	chemotaxis
OP701_RS09055	COG1776	CheC inhibitor of MCP methylation
OP701_RS09060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OP701_RS09065	COG1191	sigma factor activity
OP701_RS09075	COG0052	Belongs to the universal ribosomal protein uS2 family
OP701_RS09080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OP701_RS09085	COG0528	UMP kinase activity
OP701_RS09090	COG0233	cytoplasmic translational termination
OP701_RS09095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OP701_RS09100	COG4589	Belongs to the CDS family
OP701_RS09105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OP701_RS09110	COG0750	zinc metalloprotease
OP701_RS09115	COG0442	prolyl-tRNA aminoacylation
OP701_RS09120	COG2176	DNA-directed DNA polymerase activity
OP701_RS09125	COG0779	Required for maturation of 30S ribosomal subunits
OP701_RS09130	COG0195	Participates in both transcription termination and antitermination
OP701_RS09135	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OP701_RS09140	COG1358	cellular component organization or biogenesis
OP701_RS09145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OP701_RS09150	COG1550	Protein conserved in bacteria
OP701_RS09155	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OP701_RS09160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OP701_RS09165	COG0196	riboflavin kinase activity
OP701_RS09175	COG1185	polyribonucleotide nucleotidyltransferase activity
OP701_RS09180	COG0726	polysaccharide deacetylase
OP701_RS09185	COG0612	Peptidase, M16
OP701_RS09190	COG1873	PFAM PRC-barrel domain
OP701_RS09195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OP701_RS09200	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OP701_RS09205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OP701_RS09210	COG0527	aspartate kinase activity
OP701_RS09215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OP701_RS09220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OP701_RS09225	COG0740	serine-type endopeptidase activity
OP701_RS09235	COG1674	ftsk spoiiie
OP701_RS09235	COG4980	gas vesicle protein
OP701_RS09240	COG2188	Transcriptional regulator
OP701_RS09245	COG2814	Major facilitator Superfamily
OP701_RS09250	COG0612	Peptidase, M16
OP701_RS09255	COG0612	Peptidase, M16
OP701_RS09260	COG0300	oxidoreductase activity
OP701_RS09275	COG1426	Protein conserved in bacteria
OP701_RS09280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OP701_RS09285	COG1058	Belongs to the CinA family
OP701_RS09285	COG1546	Belongs to the CinA family
OP701_RS09290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OP701_RS09295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OP701_RS09300	COG1418	mRNA catabolic process
OP701_RS09305	COG1692	metallophosphoesterase
OP701_RS09310	COG2359	stage V sporulation protein S
OP701_RS09315	COG1063	alcohol dehydrogenase
OP701_RS09320	COG0156	8-amino-7-oxononanoate synthase activity
OP701_RS09325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OP701_RS09330	COG4550	Control of competence regulator ComK, YlbF/YmcA
OP701_RS09340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OP701_RS09345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OP701_RS09350	COG4974	Belongs to the 'phage' integrase family
OP701_RS09390	COG3226	Transcriptional regulator
OP701_RS09400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS09405	COG1404	Belongs to the peptidase S8 family
OP701_RS09415	COG4195	phage-related replication protein
OP701_RS09420	COG1764	response to oxidative stress
OP701_RS09445	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OP701_RS09450	COG1923	regulation of RNA biosynthetic process
OP701_RS09465	COG1780	Probably involved in ribonucleotide reductase function
OP701_RS09470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OP701_RS09475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OP701_RS09480	COG4112	unkown
OP701_RS09485	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP701_RS09490	COG0464	growth
OP701_RS09495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OP701_RS09500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OP701_RS09505	COG0789	Transcriptional regulator
OP701_RS09510	COG0174	glutamine synthetase
OP701_RS09545	COG2249	NAD(P)H dehydrogenase (quinone) activity
OP701_RS09550	COG1733	regulation of RNA biosynthetic process
OP701_RS09590	COG0135	phosphoribosylanthranilate isomerase activity
OP701_RS09625	COG2211	Major facilitator Superfamily
OP701_RS09630	COG3507	Belongs to the glycosyl hydrolase 43 family
OP701_RS09645	COG1070	Carbohydrate kinase
OP701_RS09655	COG1525	nuclease
OP701_RS09660	COG2814	Major facilitator Superfamily
OP701_RS09670	COG0756	dUTP diphosphatase activity
OP701_RS09720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OP701_RS09735	COG3832	glyoxalase III activity
OP701_RS09745	COG2059	Chromate
OP701_RS09750	COG0697	spore germination
OP701_RS09755	COG0531	amino acid
OP701_RS09785	COG4195	phage-related replication protein
OP701_RS09795	COG0346	lactoylglutathione lyase activity
OP701_RS09805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OP701_RS09810	COG1388	LysM domain
OP701_RS09815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OP701_RS09820	COG4224	UPF0291 protein
OP701_RS09825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OP701_RS09835	COG3763	UPF0154 protein
OP701_RS09845	COG0785	Cytochrome C biogenesis protein
OP701_RS09850	COG2201	protein-glutamate methylesterase activity
OP701_RS09855	COG4846	Membrane protein involved in cytochrome C biogenesis
OP701_RS09865	COG0071	Belongs to the small heat shock protein (HSP20) family
OP701_RS09880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OP701_RS09885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS09905	COG0824	Thioesterase
OP701_RS09915	COG4841	protein insertion into membrane
OP701_RS09920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OP701_RS09925	COG1832	CoA-binding protein
OP701_RS09930	COG0187	DNA topoisomerase II activity
OP701_RS09935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OP701_RS09950	COG1115	amino acid carrier protein
OP701_RS09965	COG5520	Belongs to the glycosyl hydrolase 30 family
OP701_RS10000	COG2246	polysaccharide biosynthetic process
OP701_RS10005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OP701_RS10010	COG0586	Pfam SNARE associated Golgi protein
OP701_RS10015	COG2404	hydrolase activity, acting on ester bonds
OP701_RS10020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OP701_RS10025	COG1024	Enoyl-CoA hydratase
OP701_RS10030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OP701_RS10035	COG0511	ligase activity, forming carbon-carbon bonds
OP701_RS10040	COG0439	Biotin carboxylase
OP701_RS10045	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS10050	COG1960	acyl-CoA dehydrogenase activity
OP701_RS10070	COG1649	PFAM Uncharacterised BCR, COG1649
OP701_RS10080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS10080	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OP701_RS10085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS10090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS10095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS10100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS10105	COG2027	D-alanyl-D-alanine carboxypeptidase
OP701_RS10110	COG2017	converts alpha-aldose to the beta-anomer
OP701_RS10115	COG0534	Mate efflux family protein
OP701_RS10130	COG0582	viral genome integration into host DNA
OP701_RS10135	COG0166	Belongs to the GPI family
OP701_RS10140	COG0405	Gamma-glutamyltransferase
OP701_RS10145	COG0583	DNA-binding transcription factor activity
OP701_RS10150	COG0604	alcohol dehydrogenase
OP701_RS10155	COG0493	'glutamate synthase
OP701_RS10160	COG0070	glutamate synthase
OP701_RS10160	COG0069	glutamate synthase activity
OP701_RS10160	COG0067	glutamate synthase
OP701_RS10165	COG0583	DNA-binding transcription factor activity
OP701_RS10170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OP701_RS10185	COG0300	oxidoreductase activity
OP701_RS10190	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OP701_RS10200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS10205	COG2814	Major facilitator Superfamily
OP701_RS10210	COG1070	Carbohydrate kinase
OP701_RS10215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OP701_RS10220	COG0243	molybdopterin cofactor binding
OP701_RS10235	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS10250	COG5278	phosphoserine phosphatase activity
OP701_RS10250	COG0840	transmembrane signaling receptor activity
OP701_RS10255	COG2368	4-hydroxyphenylacetate
OP701_RS10260	COG4305	rare lipoprotein A
OP701_RS10265	COG3619	membrane
OP701_RS10290	COG2135	peptidase activity
OP701_RS10300	COG2140	Oxalate decarboxylase
OP701_RS10310	COG0457	Tetratricopeptide repeat
OP701_RS10335	COG2720	vancomycin resistance protein
OP701_RS10350	COG3739	integral membrane protein
OP701_RS10355	COG0583	DNA-binding transcription factor activity
OP701_RS10360	COG0697	spore germination
OP701_RS10365	COG1388	LysM domain
OP701_RS10375	COG0693	protein deglycase activity
OP701_RS10380	COG2367	Beta-lactamase
OP701_RS10390	COG3397	chitin binding
OP701_RS10395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP701_RS10400	COG0574	Belongs to the PEP-utilizing enzyme family
OP701_RS10400	COG3848	Pyruvate phosphate dikinase
OP701_RS10420	COG4282	regulation of fungal-type cell wall biogenesis
OP701_RS10425	COG1231	oxidoreductase activity
OP701_RS10435	COG0726	polysaccharide deacetylase
OP701_RS10510	COG3655	Transcriptional regulator
OP701_RS10550	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OP701_RS10555	COG0463	Glycosyl transferase, family 2
OP701_RS10560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS10565	COG2274	protein secretion by the type I secretion system
OP701_RS10565	COG3271	cysteine-type peptidase activity
OP701_RS10580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OP701_RS10650	COG1404	Belongs to the peptidase S8 family
OP701_RS10660	COG1404	Belongs to the peptidase S8 family
OP701_RS10670	COG0577	efflux transmembrane transporter activity
OP701_RS10670	COG1136	(ABC) transporter
OP701_RS10685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP701_RS10690	COG2207	Transcriptional regulator
OP701_RS10690	COG0662	Cupin 2, conserved barrel domain protein
OP701_RS10695	COG0456	acetyltransferase
OP701_RS10700	COG1309	transcriptional regulator
OP701_RS10705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS10710	COG3708	Transcriptional regulator
OP701_RS10715	COG2378	regulation of single-species biofilm formation
OP701_RS10725	COG0640	Transcriptional regulator
OP701_RS10730	COG0741	lytic transglycosylase activity
OP701_RS10735	COG2322	membrane
OP701_RS10750	COG1619	proteins homologs of microcin C7 resistance protein MccF
OP701_RS10755	COG3239	Fatty acid desaturase
OP701_RS10760	COG4585	Histidine kinase
OP701_RS10765	COG2197	response regulator
OP701_RS10770	COG3584	3D domain protein
OP701_RS10770	COG1388	LysM domain
OP701_RS10775	COG0514	ATP-dependent DNA helicase (RecQ)
OP701_RS10785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OP701_RS10790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OP701_RS10805	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS10810	COG1657	PFAM Prenyltransferase squalene oxidase
OP701_RS10815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OP701_RS10820	COG0733	neurotransmitter:sodium symporter activity
OP701_RS10825	COG0385	Bile acid
OP701_RS10830	COG0508	dehydrogenase complex catalyzes the overall conversion of
OP701_RS10835	COG0567	Dehydrogenase, E1 component
OP701_RS10840	COG4548	von Willebrand factor, type A
OP701_RS10845	COG0714	Associated with various cellular activities
OP701_RS10850	COG2032	superoxide dismutase activity
OP701_RS10855	COG0791	NLP P60 protein
OP701_RS10855	COG1388	LysM domain
OP701_RS10860	COG1819	glycosyl
OP701_RS10865	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OP701_RS10870	COG0534	Mate efflux family protein
OP701_RS10875	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS10880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OP701_RS10885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OP701_RS10895	COG2962	Rard protein
OP701_RS10910	COG2610	gluconate transmembrane transporter activity
OP701_RS10915	COG1942	4-Oxalocrotonate Tautomerase
OP701_RS10925	COG1733	regulation of RNA biosynthetic process
OP701_RS10930	COG0778	Nitroreductase
OP701_RS10935	COG0400	carboxylic ester hydrolase activity
OP701_RS10940	COG0346	lactoylglutathione lyase activity
OP701_RS10950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OP701_RS10955	COG0793	Belongs to the peptidase S41A family
OP701_RS10955	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS10960	COG2226	methyltransferase
OP701_RS10970	COG1876	peptidase activity
OP701_RS10975	COG0813	purine-nucleoside phosphorylase activity
OP701_RS10990	COG0671	phosphoesterase, PA-phosphatase related
OP701_RS11010	COG4479	Belongs to the UPF0346 family
OP701_RS11020	COG1509	lysine 2,3-aminomutase activity
OP701_RS11025	COG0456	acetyltransferase
OP701_RS11030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OP701_RS11035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OP701_RS11040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OP701_RS11045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OP701_RS11055	COG0456	acetyltransferase
OP701_RS11060	COG0463	Glycosyl transferase, family 2
OP701_RS11075	COG4641	Protein conserved in bacteria
OP701_RS11080	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
OP701_RS11085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OP701_RS11090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OP701_RS11095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OP701_RS11100	COG1846	Transcriptional regulator
OP701_RS11105	COG0534	Mate efflux family protein
OP701_RS11115	COG4698	Protein conserved in bacteria
OP701_RS11120	COG2755	lipolytic protein G-D-S-L family
OP701_RS11125	COG1999	signal sequence binding
OP701_RS11135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OP701_RS11140	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OP701_RS11145	COG1272	protein, Hemolysin III
OP701_RS11150	COG0204	Acyl-transferase
OP701_RS11155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OP701_RS11165	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OP701_RS11175	COG2136	Putative SAM-dependent methyltransferase
OP701_RS11175	COG2521	methyltransferase
OP701_RS11185	COG0129	dihydroxy-acid dehydratase activity
OP701_RS11190	COG1413	lyase activity
OP701_RS11195	COG1418	mRNA catabolic process
OP701_RS11200	COG0386	Belongs to the glutathione peroxidase family
OP701_RS11205	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OP701_RS11210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OP701_RS11220	COG1278	Cold shock
OP701_RS11240	COG0328	RNA-DNA hybrid ribonuclease activity
OP701_RS11245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OP701_RS11250	COG0328	RNA-DNA hybrid ribonuclease activity
OP701_RS11260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OP701_RS11275	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OP701_RS11285	COG1755	Isoprenylcysteine carboxyl methyltransferase
OP701_RS11290	COG3424	synthase
OP701_RS11295	COG2233	PERMEase
OP701_RS11300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OP701_RS11305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OP701_RS11315	COG0800	Aldolase
OP701_RS11320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP701_RS11325	COG1609	Transcriptional regulator
OP701_RS11330	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OP701_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS11340	COG1199	ATP-dependent helicase activity
OP701_RS11355	COG0116	Belongs to the methyltransferase superfamily
OP701_RS11370	COG4474	Belongs to the UPF0398 family
OP701_RS11385	COG3359	exonuclease
OP701_RS11390	COG1111	helicase
OP701_RS11390	COG1205	dead DEAH box helicase
OP701_RS11395	COG2190	(PTS) system
OP701_RS11400	COG0071	Belongs to the small heat shock protein (HSP20) family
OP701_RS11435	COG3331	DNA recombination
OP701_RS11440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OP701_RS11440	COG4499	WXG100 protein secretion system (Wss), protein YukC
OP701_RS11450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OP701_RS11455	COG3935	DnaD domain protein
OP701_RS11460	COG0017	Asparaginyl-tRNA synthetase
OP701_RS11465	COG0436	Aminotransferase
OP701_RS11470	COG5353	protein conserved in bacteria
OP701_RS11480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OP701_RS11480	COG1199	ATP-dependent helicase activity
OP701_RS11485	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OP701_RS11490	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OP701_RS11495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OP701_RS11500	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OP701_RS11500	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OP701_RS11505	COG0617	tRNA 3'-terminal CCA addition
OP701_RS11510	COG0438	transferase activity, transferring glycosyl groups
OP701_RS11515	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OP701_RS11520	COG1803	Methylglyoxal synthase
OP701_RS11525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OP701_RS11530	COG1694	Mazg nucleotide pyrophosphohydrolase
OP701_RS11535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS11545	COG4347	Protein of unknown function (DUF1405)
OP701_RS11550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OP701_RS11550	COG2010	Cytochrome c
OP701_RS11555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OP701_RS11560	COG0723	plastoquinol--plastocyanin reductase activity
OP701_RS11570	COG5582	Belongs to the UPF0302 family
OP701_RS11575	COG0457	Tetratricopeptide repeat
OP701_RS11580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OP701_RS11585	COG0287	Prephenate dehydrogenase
OP701_RS11590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OP701_RS11595	COG0159	tryptophan synthase activity
OP701_RS11600	COG0133	tryptophan synthase activity
OP701_RS11605	COG0135	phosphoribosylanthranilate isomerase activity
OP701_RS11615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OP701_RS11620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OP701_RS11625	COG4401	Chorismate mutase type I
OP701_RS11630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OP701_RS11635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OP701_RS11640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OP701_RS11645	COG0105	UTP biosynthetic process
OP701_RS11650	COG0142	geranyltranstransferase activity
OP701_RS11655	COG2226	methyltransferase
OP701_RS11660	COG0142	geranyltranstransferase activity
OP701_RS11670	COG0302	gtp cyclohydrolase
OP701_RS11675	COG0776	regulation of translation
OP701_RS11680	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OP701_RS11695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OP701_RS11700	COG1160	GTP binding
OP701_RS11725	COG1304	FMN binding
OP701_RS11730	COG0539	negative regulation of cytoplasmic translation
OP701_RS11735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OP701_RS11745	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OP701_RS11750	COG2959	enzyme of heme biosynthesis
OP701_RS11755	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS11755	COG3773	Cell wall hydrolase
OP701_RS11760	COG2339	peptidase activity
OP701_RS11765	COG0492	ferredoxin-NADP+ reductase activity
OP701_RS11770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OP701_RS11775	COG4862	establishment of competence for transformation
OP701_RS11780	COG1408	metallophosphoesterase
OP701_RS11790	COG1388	LysM domain
OP701_RS11795	COG1266	CAAX protease self-immunity
OP701_RS11800	COG0514	ATP-dependent DNA helicase (RecQ)
OP701_RS11805	COG4955	Helix-turn-helix domain
OP701_RS11810	COG1141	Ferredoxin
OP701_RS11815	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OP701_RS11820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OP701_RS11825	COG0710	3-dehydroquinate dehydratase activity
OP701_RS11835	COG1595	DNA-templated transcription, initiation
OP701_RS11840	COG5002	protein histidine kinase activity
OP701_RS11845	COG0745	RESPONSE REGULATOR receiver
OP701_RS11850	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OP701_RS11855	COG1333	cytochrome c biogenesis protein
OP701_RS11860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS11865	COG1187	pseudouridine synthase activity
OP701_RS11870	COG0700	Nucleoside recognition
OP701_RS11875	COG2715	membrane protein required for spore maturation
OP701_RS11880	COG1686	Belongs to the peptidase S11 family
OP701_RS11890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OP701_RS11895	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OP701_RS11900	COG1547	Domain of unknown function (DUF309)
OP701_RS11905	COG0456	acetyltransferase
OP701_RS11910	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OP701_RS11915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OP701_RS11915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OP701_RS11920	COG0307	riboflavin synthase, alpha
OP701_RS11925	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OP701_RS11925	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OP701_RS11940	COG0681	Belongs to the peptidase S26 family
OP701_RS11945	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
OP701_RS11960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OP701_RS11965	COG4086	secreted protein
OP701_RS11970	COG0019	diaminopimelate decarboxylase activity
OP701_RS11975	COG0697	spore germination
OP701_RS11990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OP701_RS12010	COG1191	sigma factor activity
OP701_RS12020	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS12025	COG1686	Belongs to the peptidase S11 family
OP701_RS12030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OP701_RS12035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OP701_RS12040	COG4974	Belongs to the 'phage' integrase family
OP701_RS12050	COG0735	belongs to the Fur family
OP701_RS12055	COG1300	Membrane
OP701_RS12065	COG0281	malic enzyme
OP701_RS12070	COG1757	Na H antiporter
OP701_RS12075	COG1027	Aspartate ammonia-lyase
OP701_RS12080	COG0252	asparaginase activity
OP701_RS12085	COG1396	sequence-specific DNA binding
OP701_RS12090	COG1379	DNA repair
OP701_RS12095	COG0494	nUDIX hydrolase
OP701_RS12105	COG0667	Aldo Keto reductase
OP701_RS12115	COG1073	alpha beta
OP701_RS12125	COG4918	Iron-sulphur cluster biosynthesis
OP701_RS12130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OP701_RS12130	COG0456	acetyltransferase
OP701_RS12135	COG2329	Antibiotic biosynthesis monooxygenase
OP701_RS12140	COG0456	acetyltransferase
OP701_RS12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OP701_RS12180	COG1072	(Pantothenic acid kinase))
OP701_RS12185	COG3048	D-serine ammonia-lyase activity
OP701_RS12190	COG0300	oxidoreductase activity
OP701_RS12195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS12200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OP701_RS12205	COG4187	Peptidase family M20/M25/M40
OP701_RS12210	COG1902	pentaerythritol trinitrate reductase activity
OP701_RS12215	COG0596	Alpha beta hydrolase
OP701_RS12225	COG1234	tRNA 3'-trailer cleavage
OP701_RS12230	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OP701_RS12235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OP701_RS12240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OP701_RS12250	COG0706	membrane insertase activity
OP701_RS12255	COG3361	conserved protein (COG2071)
OP701_RS12260	COG2195	Cleaves the N-terminal amino acid of tripeptides
OP701_RS12265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OP701_RS12270	COG0346	lactoylglutathione lyase activity
OP701_RS12280	COG1376	ErfK ybiS ycfS ynhG family protein
OP701_RS12285	COG4129	membrane
OP701_RS12290	COG1126	abc transporter atp-binding protein
OP701_RS12295	COG0765	amino acid transport
OP701_RS12300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS12310	COG1597	lipid kinase activity
OP701_RS12315	COG2814	Major facilitator Superfamily
OP701_RS12320	COG0789	Transcriptional regulator
OP701_RS12320	COG4978	Transcriptional regulator
OP701_RS12325	COG0508	dehydrogenase complex catalyzes the overall conversion of
OP701_RS12330	COG0022	dehydrogenase e1 component
OP701_RS12335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OP701_RS12340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP701_RS12345	COG3426	butyrate kinase activity
OP701_RS12350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OP701_RS12355	COG0280	phosphate acetyltransferase
OP701_RS12360	COG3829	transcription factor binding
OP701_RS12360	COG3290	protein histidine kinase activity
OP701_RS12370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OP701_RS12375	COG2079	MmgE PrpD family protein
OP701_RS12380	COG0372	Belongs to the citrate synthase family
OP701_RS12385	COG1960	acyl-CoA dehydrogenase activity
OP701_RS12390	COG1250	3-hydroxyacyl-CoA dehydrogenase
OP701_RS12395	COG0183	Belongs to the thiolase family
OP701_RS12400	COG0584	glycerophosphoryl diester phosphodiesterase
OP701_RS12405	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP701_RS12420	COG1902	pentaerythritol trinitrate reductase activity
OP701_RS12430	COG0745	RESPONSE REGULATOR receiver
OP701_RS12435	COG0750	zinc metalloprotease
OP701_RS12440	COG0497	DNA recombination
OP701_RS12445	COG1438	arginine binding
OP701_RS12450	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OP701_RS12455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OP701_RS12460	COG0142	geranyltranstransferase activity
OP701_RS12465	COG1722	exodeoxyribonuclease VII activity
OP701_RS12470	COG1570	exodeoxyribonuclease VII activity
OP701_RS12475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OP701_RS12480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OP701_RS12485	COG1302	Protein conserved in bacteria
OP701_RS12490	COG0439	Biotin carboxylase
OP701_RS12495	COG0511	ligase activity, forming carbon-carbon bonds
OP701_RS12535	COG3854	ATPases associated with a variety of cellular activities
OP701_RS12545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OP701_RS12550	COG0006	proline dipeptidase activity
OP701_RS12555	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OP701_RS12565	COG3872	metal-dependent enzyme
OP701_RS12575	COG1752	Esterase of the alpha-beta hydrolase superfamily
OP701_RS12580	COG1321	iron dependent repressor
OP701_RS12585	COG0095	Lipoate-protein ligase
OP701_RS12590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OP701_RS12595	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OP701_RS12600	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OP701_RS12605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OP701_RS12610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OP701_RS12625	COG1396	sequence-specific DNA binding
OP701_RS12635	COG0681	Belongs to the peptidase S26 family
OP701_RS12660	COG4940	Competence protein ComGF
OP701_RS12670	COG4970	Tfp pilus assembly protein FimT
OP701_RS12675	COG4537	Required for transformation and DNA binding
OP701_RS12680	COG1459	type II secretion system
OP701_RS12685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OP701_RS12695	COG0517	IMP dehydrogenase activity
OP701_RS12700	COG0598	Magnesium transport protein CorA
OP701_RS12705	COG1253	flavin adenine dinucleotide binding
OP701_RS12710	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS12720	COG1393	Belongs to the ArsC family
OP701_RS12730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS12740	COG0011	TIGRFAM Protein of
OP701_RS12750	COG2866	Carboxypeptidase
OP701_RS12755	COG1368	sulfuric ester hydrolase activity
OP701_RS12760	COG1940	carbohydrate kinase activity
OP701_RS12770	COG0457	Tetratricopeptide repeat
OP701_RS12770	COG0705	Rhomboid family
OP701_RS12780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OP701_RS12790	COG0438	transferase activity, transferring glycosyl groups
OP701_RS12805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OP701_RS12810	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OP701_RS12815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OP701_RS12820	COG0581	inorganic phosphate transmembrane transporter activity
OP701_RS12825	COG0573	inorganic phosphate transmembrane transporter activity
OP701_RS12830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OP701_RS12835	COG0768	penicillin binding
OP701_RS12840	COG0477	Major facilitator Superfamily
OP701_RS12845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OP701_RS12850	COG2839	Protein conserved in bacteria
OP701_RS12855	COG5521	maltodextrose utilization protein MalA
OP701_RS12860	COG1388	LysM domain
OP701_RS12865	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OP701_RS12870	COG4709	membrane
OP701_RS12875	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OP701_RS12880	COG0735	belongs to the Fur family
OP701_RS12885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS12895	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OP701_RS12900	COG0513	Belongs to the DEAD box helicase family
OP701_RS12910	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OP701_RS12915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OP701_RS12920	COG2384	SAM-dependent methyltransferase
OP701_RS12925	COG2010	Cytochrome c
OP701_RS12930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OP701_RS12935	COG0358	DNA primase activity
OP701_RS12940	COG1671	Belongs to the UPF0178 family
OP701_RS12945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OP701_RS12950	COG0517	IMP dehydrogenase activity
OP701_RS12955	COG0751	glycine-tRNA ligase activity
OP701_RS12960	COG0752	glycyl-tRNA synthetase alpha subunit
OP701_RS12965	COG1381	Involved in DNA repair and RecF pathway recombination
OP701_RS12975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OP701_RS12980	COG0295	cytidine deaminase activity
OP701_RS12985	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OP701_RS12990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OP701_RS12995	COG1480	7TM receptor with intracellular HD hydrolase
OP701_RS13000	COG1702	phosphate starvation-inducible protein PhoH
OP701_RS13005	COG0561	phosphatase activity
OP701_RS13020	COG4864	UPF0365 protein
OP701_RS13025	COG1030	water channel activity
OP701_RS13030	COG1610	YqeY-like protein
OP701_RS13040	COG1283	sodium-dependent phosphate transmembrane transporter activity
OP701_RS13045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OP701_RS13050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OP701_RS13055	COG2264	protein methyltransferase activity
OP701_RS13070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OP701_RS13075	COG1420	regulation of RNA biosynthetic process
OP701_RS13080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OP701_RS13085	COG0481	GTPase activity
OP701_RS13095	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP701_RS13100	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OP701_RS13105	COG0268	Binds directly to 16S ribosomal RNA
OP701_RS13110	COG1466	dna polymerase III delta subunit
OP701_RS13125	COG2333	competence protein COMEC
OP701_RS13125	COG0658	competence protein
OP701_RS13130	COG2131	deaminase
OP701_RS13135	COG1596	polysaccharide export
OP701_RS13135	COG1555	photosystem II stabilization
OP701_RS13140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OP701_RS13145	COG2226	methyltransferase
OP701_RS13150	COG0799	negative regulation of ribosome biogenesis
OP701_RS13155	COG1713	HD superfamily hydrolase involved in NAD metabolism
OP701_RS13160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OP701_RS13165	COG1534	Rna-binding protein
OP701_RS13170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OP701_RS13175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OP701_RS13180	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OP701_RS13195	COG2755	lipolytic protein G-D-S-L family
OP701_RS13200	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS13200	COG5632	N-Acetylmuramoyl-L-alanine amidase
OP701_RS13205	COG0398	Pfam SNARE associated Golgi protein
OP701_RS13210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OP701_RS13220	COG3209	COG3209 Rhs family protein
OP701_RS13245	COG2814	Major facilitator Superfamily
OP701_RS13250	COG2814	Major facilitator Superfamily
OP701_RS13255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OP701_RS13260	COG1335	isochorismatase
OP701_RS13265	COG1522	sequence-specific DNA binding
OP701_RS13270	COG1522	sequence-specific DNA binding
OP701_RS13275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS13280	COG0730	response to heat
OP701_RS13285	COG0425	Belongs to the sulfur carrier protein TusA family
OP701_RS13300	COG0425	Belongs to the sulfur carrier protein TusA family
OP701_RS13300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OP701_RS13310	COG2210	Belongs to the sulfur carrier protein TusA family
OP701_RS13315	COG1937	Protein conserved in bacteria
OP701_RS13340	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS13345	COG1309	transcriptional regulator
OP701_RS13350	COG2085	NADP oxidoreductase coenzyme F420-dependent
OP701_RS13355	COG1733	regulation of RNA biosynthetic process
OP701_RS13380	COG0457	Tetratricopeptide repeat
OP701_RS13390	COG5444	nuclease activity
OP701_RS13395	COG4282	regulation of fungal-type cell wall biogenesis
OP701_RS13410	COG2732	(Barnase) inhibitor
OP701_RS13420	COG4824	toxin secretion phage lysis holin
OP701_RS13445	COG0563	adenylate kinase activity
OP701_RS13455	COG0583	DNA-binding transcription factor activity
OP701_RS13465	COG0697	spore germination
OP701_RS13470	COG0583	DNA-binding transcription factor activity
OP701_RS13475	COG4124	Belongs to the glycosyl hydrolase 26 family
OP701_RS13485	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS13485	COG2207	Transcriptional regulator
OP701_RS13490	COG0697	spore germination
OP701_RS13495	COG1802	Transcriptional regulator
OP701_RS13500	COG2318	DinB family
OP701_RS13505	COG0456	acetyltransferase
OP701_RS13510	COG0477	Major facilitator Superfamily
OP701_RS13515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP701_RS13540	COG0747	negative chemotaxis
OP701_RS13545	COG0601	transmembrane transport
OP701_RS13550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP701_RS13555	COG0444	Belongs to the ABC transporter superfamily
OP701_RS13560	COG4608	Belongs to the ABC transporter superfamily
OP701_RS13565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OP701_RS13575	COG3443	Belongs to the bacterial solute-binding protein 9 family
OP701_RS13580	COG1595	DNA-templated transcription, initiation
OP701_RS13585	COG0667	Aldo Keto reductase
OP701_RS13590	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS13595	COG5566	PFAM Mor transcription activator
OP701_RS13600	COG0596	Alpha beta hydrolase
OP701_RS13605	COG0697	spore germination
OP701_RS13610	COG0110	maltose O-acetyltransferase activity
OP701_RS13615	COG4991	sh3 domain protein
OP701_RS13620	COG4991	sh3 domain protein
OP701_RS13630	COG5577	PFAM Coat F domain
OP701_RS13635	COG1063	alcohol dehydrogenase
OP701_RS13645	COG5577	PFAM Coat F domain
OP701_RS13655	COG0667	Aldo Keto reductase
OP701_RS13660	COG2207	Transcriptional regulator
OP701_RS13665	COG0789	Transcriptional regulator
OP701_RS13670	COG0789	Transcriptional regulator
OP701_RS13680	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OP701_RS13685	COG1064	alcohol dehydrogenase
OP701_RS13690	COG0693	protein deglycase activity
OP701_RS13695	COG1621	beta-fructofuranosidase activity
OP701_RS13705	COG3716	PTS system mannose fructose sorbose family IID component
OP701_RS13710	COG3715	PTS system
OP701_RS13715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS13720	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS13725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OP701_RS13725	COG3933	PFAM sigma-54 factor interaction domain-containing protein
OP701_RS13735	COG1113	amino acid transport
OP701_RS13740	COG1280	lysine exporter protein (LysE YggA)
OP701_RS13745	COG1378	Sugar-specific transcriptional regulator TrmB
OP701_RS13750	COG1595	DNA-templated transcription, initiation
OP701_RS13760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OP701_RS13760	COG2755	lipolytic protein G-D-S-L family
OP701_RS13770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OP701_RS13770	COG2124	cytochrome p450
OP701_RS13775	COG1309	transcriptional regulator
OP701_RS13780	COG2226	methyltransferase
OP701_RS13795	COG2116	formate transmembrane transporter activity
OP701_RS13800	COG5609	conserved protein (DUF2294)
OP701_RS13805	COG3383	formate dehydrogenase (NAD+) activity
OP701_RS13810	COG2427	Protein of unknown function (DUF1641)
OP701_RS13820	COG0626	cystathionine gamma-synthase activity
OP701_RS13825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OP701_RS13830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OP701_RS13835	COG2226	methyltransferase
OP701_RS13850	COG0768	penicillin binding
OP701_RS13855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OP701_RS13860	COG0572	uridine kinase
OP701_RS13865	COG0826	peptidase U32
OP701_RS13870	COG0826	peptidase U32
OP701_RS13875	COG4122	O-methyltransferase activity
OP701_RS13880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OP701_RS13885	COG3906	Belongs to the UPF0473 family
OP701_RS13890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OP701_RS13895	COG4472	Bacterial protein of unknown function (DUF965)
OP701_RS13900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OP701_RS13905	COG0628	permease
OP701_RS13910	COG1126	abc transporter atp-binding protein
OP701_RS13915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS13920	COG0765	amino acid transport
OP701_RS13925	COG0765	amino acid transport
OP701_RS13940	COG3881	PFAM PRC-barrel domain
OP701_RS13945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OP701_RS13950	COG0457	Tetratricopeptide repeat
OP701_RS13955	COG0482	sulfurtransferase activity
OP701_RS13960	COG1104	cysteine desulfurase activity
OP701_RS13965	COG1959	2 iron, 2 sulfur cluster binding
OP701_RS13970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OP701_RS13975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OP701_RS13985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OP701_RS13990	COG0124	histidyl-tRNA synthetase
OP701_RS14000	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP701_RS14000	COG3103	Sh3 type 3 domain protein
OP701_RS14000	COG4991	sh3 domain protein
OP701_RS14005	COG1490	D-aminoacyl-tRNA deacylase activity
OP701_RS14010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OP701_RS14015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OP701_RS14020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OP701_RS14020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OP701_RS14025	COG5416	Lipopolysaccharide assembly protein A domain
OP701_RS14030	COG0490	domain, Protein
OP701_RS14035	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OP701_RS14035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OP701_RS14045	COG2244	polysaccharide biosynthetic process
OP701_RS14050	COG2323	membrane
OP701_RS14060	COG1862	Preprotein translocase
OP701_RS14065	COG0343	queuine tRNA-ribosyltransferase activity
OP701_RS14070	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OP701_RS14080	COG2255	four-way junction helicase activity
OP701_RS14085	COG0632	four-way junction helicase activity
OP701_RS14095	COG2814	Major facilitator Superfamily
OP701_RS14100	COG0673	inositol 2-dehydrogenase activity
OP701_RS14105	COG2112	serine threonine protein kinase
OP701_RS14125	COG1115	amino acid carrier protein
OP701_RS14130	COG0217	transcriptional regulatory protein
OP701_RS14140	COG1388	LysM domain
OP701_RS14145	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OP701_RS14150	COG0157	Belongs to the NadC ModD family
OP701_RS14155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OP701_RS14160	COG1104	cysteine desulfurase activity
OP701_RS14165	COG1827	regulation of RNA biosynthetic process
OP701_RS14170	COG0077	Prephenate dehydratase
OP701_RS14175	COG4492	Belongs to the UPF0735 family
OP701_RS14180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OP701_RS14185	COG3290	protein histidine kinase activity
OP701_RS14195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OP701_RS14200	COG2868	ribosomal protein
OP701_RS14205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OP701_RS14210	COG1994	Peptidase M50
OP701_RS14215	COG0739	heme binding
OP701_RS14220	COG2894	cell division
OP701_RS14225	COG0850	regulation of cytokinetic process
OP701_RS14230	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OP701_RS14240	COG1077	Cell shape determining protein MreB Mrl
OP701_RS14290	COG0457	Tetratricopeptide repeat
OP701_RS14295	COG5444	nuclease activity
OP701_RS14305	COG5632	N-Acetylmuramoyl-L-alanine amidase
OP701_RS14305	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS14305	COG1388	LysM domain
OP701_RS14350	COG1705	Flagellar rod assembly protein muramidase FlgJ
OP701_RS14360	COG3953	SLT domain
OP701_RS14360	COG5280	Phage tail tape measure protein TP901
OP701_RS14540	COG0424	maF-like protein
OP701_RS14550	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OP701_RS14555	COG0285	dihydrofolate synthase activity
OP701_RS14560	COG0525	valine-tRNA ligase activity
OP701_RS14570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OP701_RS14575	COG1388	LysM domain
OP701_RS14580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OP701_RS14585	COG0113	porphobilinogen synthase activity
OP701_RS14590	COG1587	Uroporphyrinogen-III synthase
OP701_RS14595	COG0181	hydroxymethylbilane synthase activity
OP701_RS14600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OP701_RS14605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OP701_RS14615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OP701_RS14620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OP701_RS14625	COG0470	DNA polymerase III
OP701_RS14625	COG1067	ATP-dependent peptidase activity
OP701_RS14630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OP701_RS14635	COG0544	peptidyl-prolyl cis-trans isomerase activity
OP701_RS14640	COG0457	Tetratricopeptide repeat
OP701_RS14640	COG1477	protein flavinylation
OP701_RS14645	COG0066	3-isopropylmalate dehydratase activity
OP701_RS14650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OP701_RS14655	COG0473	3-isopropylmalate dehydrogenase activity
OP701_RS14660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OP701_RS14665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OP701_RS14670	COG0440	acetolactate synthase activity
OP701_RS14675	COG0028	Belongs to the TPP enzyme family
OP701_RS14685	COG0454	-acetyltransferase
OP701_RS14690	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OP701_RS14700	COG0622	Phosphoesterase
OP701_RS14705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OP701_RS14710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OP701_RS14715	COG5401	PFAM Sporulation and spore germination
OP701_RS14720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OP701_RS14725	COG1846	Transcriptional regulator
OP701_RS14730	COG2197	response regulator
OP701_RS14735	COG0824	Thioesterase
OP701_RS14740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OP701_RS14745	COG1053	succinate dehydrogenase
OP701_RS14750	COG2009	succinate dehydrogenase
OP701_RS14755	COG1719	4-vinyl reductase, 4VR
OP701_RS14760	COG0527	aspartate kinase activity
OP701_RS14765	COG0322	excinuclease ABC activity
OP701_RS14770	COG3118	belongs to the thioredoxin family
OP701_RS14775	COG3534	alpha-L-arabinofuranosidase
OP701_RS14780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OP701_RS14785	COG2086	electron transfer activity
OP701_RS14790	COG1024	Enoyl-CoA hydratase
OP701_RS14795	COG1309	transcriptional regulator
OP701_RS14800	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS14805	COG3766	membrane
OP701_RS14810	COG1193	negative regulation of DNA recombination
OP701_RS14815	COG1796	DNA polymerase
OP701_RS14815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OP701_RS14820	COG1286	toxin biosynthetic process
OP701_RS14825	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OP701_RS14830	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OP701_RS14835	COG0072	phenylalanine-tRNA ligase activity
OP701_RS14835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP701_RS14840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OP701_RS14850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OP701_RS14860	COG3835	regulator
OP701_RS14865	COG0277	FAD linked oxidase domain protein
OP701_RS14870	COG0247	lactate metabolic process
OP701_RS14875	COG0346	lactoylglutathione lyase activity
OP701_RS14885	COG1966	Carbon starvation protein
OP701_RS14900	COG1695	Transcriptional regulator
OP701_RS14905	COG3534	alpha-L-arabinofuranosidase
OP701_RS14910	COG0395	ABC-type sugar transport system, permease component
OP701_RS14915	COG1175	transmembrane transport
OP701_RS14920	COG1653	transport
OP701_RS14925	COG0371	Dehydrogenase
OP701_RS14930	COG0647	UMP catabolic process
OP701_RS14935	COG0235	Class ii aldolase
OP701_RS14940	COG1069	ribulokinase activity
OP701_RS14945	COG2160	L-arabinose isomerase activity
OP701_RS14950	COG3507	Belongs to the glycosyl hydrolase 43 family
OP701_RS14955	COG1363	Peptidase, m42
OP701_RS14965	COG3326	Membrane
OP701_RS14970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OP701_RS14975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OP701_RS14980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OP701_RS14990	COG1346	cytolysis
OP701_RS14995	COG1380	Effector of murein hydrolase LrgA
OP701_RS15000	COG3279	Response regulator of the LytR AlgR family
OP701_RS15005	COG3275	phosphorelay sensor kinase activity
OP701_RS15010	COG1011	Hydrolase
OP701_RS15015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OP701_RS15025	COG0398	Pfam SNARE associated Golgi protein
OP701_RS15030	COG1484	DNA-dependent DNA replication
OP701_RS15035	COG3611	Membrane attachment protein
OP701_RS15040	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OP701_RS15045	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OP701_RS15050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OP701_RS15055	COG1733	regulation of RNA biosynthetic process
OP701_RS15060	COG2814	Major facilitator Superfamily
OP701_RS15065	COG0656	L-ascorbic acid biosynthetic process
OP701_RS15070	COG0237	dephospho-CoA kinase activity
OP701_RS15080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OP701_RS15085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OP701_RS15085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OP701_RS15090	COG5002	protein histidine kinase activity
OP701_RS15095	COG0745	RESPONSE REGULATOR receiver
OP701_RS15100	COG0039	L-malate dehydrogenase activity
OP701_RS15105	COG0538	isocitrate dehydrogenase activity
OP701_RS15110	COG0372	Belongs to the citrate synthase family
OP701_RS15115	COG2707	UPF0756 membrane protein
OP701_RS15120	COG0628	permease
OP701_RS15125	COG3030	protein affecting phage T7 exclusion by the F plasmid
OP701_RS15130	COG0469	pyruvate kinase activity
OP701_RS15135	COG0205	6-phosphofructokinase activity
OP701_RS15140	COG0825	malonyl-CoA metabolic process
OP701_RS15145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OP701_RS15150	COG0281	malic enzyme
OP701_RS15155	COG0587	DNA-directed DNA polymerase activity
OP701_RS15175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OP701_RS15185	COG4109	DRTGG domain
OP701_RS15190	COG0730	response to heat
OP701_RS15200	COG0196	riboflavin kinase activity
OP701_RS15205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS15210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OP701_RS15215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS15220	COG1126	abc transporter atp-binding protein
OP701_RS15225	COG0765	amino acid transport
OP701_RS15230	COG0765	amino acid transport
OP701_RS15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS15240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS15245	COG0454	-acetyltransferase
OP701_RS15250	COG0583	DNA-binding transcription factor activity
OP701_RS15255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OP701_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS15270	COG0165	Argininosuccinate lyase
OP701_RS15275	COG0137	argininosuccinate synthase activity
OP701_RS15280	COG0521	Mo-molybdopterin cofactor biosynthetic process
OP701_RS15285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OP701_RS15290	COG0827	DNA restriction-modification system
OP701_RS15295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OP701_RS15300	COG3874	Sporulation protein YtfJ
OP701_RS15310	COG1714	RDD family
OP701_RS15315	COG0616	signal peptide processing
OP701_RS15320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OP701_RS15325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OP701_RS15330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OP701_RS15340	COG0301	tRNA thio-modification
OP701_RS15345	COG1104	cysteine desulfurase activity
OP701_RS15350	COG1114	Component of the transport system for branched-chain amino acids
OP701_RS15355	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OP701_RS15360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OP701_RS15365	COG1309	transcriptional regulator
OP701_RS15370	COG1956	GAF domain-containing protein
OP701_RS15375	COG2199	diguanylate cyclase activity
OP701_RS15375	COG2203	Gaf domain
OP701_RS15380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OP701_RS15390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OP701_RS15395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OP701_RS15400	COG0454	-acetyltransferase
OP701_RS15405	COG0517	IMP dehydrogenase activity
OP701_RS15410	COG0123	including yeast histone deacetylase and acetoin utilization protein
OP701_RS15415	COG1360	Flagellar Motor Protein
OP701_RS15420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OP701_RS15425	COG1609	Transcriptional regulator
OP701_RS15430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OP701_RS15430	COG1605	Chorismate mutase
OP701_RS15435	COG3118	belongs to the thioredoxin family
OP701_RS15440	COG4980	gas vesicle protein
OP701_RS15445	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OP701_RS15450	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OP701_RS15455	COG1674	ftsk spoiiie
OP701_RS15460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP701_RS15465	COG4848	Belongs to the UPF0354 family
OP701_RS15470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS15485	COG1363	Peptidase, m42
OP701_RS15490	COG5584	Small secreted protein
OP701_RS15495	COG0281	malic enzyme
OP701_RS15500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS15505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OP701_RS15515	COG0510	thiamine kinase activity
OP701_RS15520	COG1523	belongs to the glycosyl hydrolase 13 family
OP701_RS15525	COG1597	lipid kinase activity
OP701_RS15535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OP701_RS15540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OP701_RS15545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OP701_RS15550	COG2252	PERMEase
OP701_RS15555	COG4473	ABC transporter
OP701_RS15560	COG1131	(ABC) transporter
OP701_RS15565	COG1349	DNA-binding transcription factor activity
OP701_RS15570	COG1187	pseudouridine synthase activity
OP701_RS15575	COG2244	polysaccharide biosynthetic process
OP701_RS15580	COG2081	HI0933 family
OP701_RS15585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OP701_RS15595	COG5578	integral membrane protein
OP701_RS15600	COG0673	inositol 2-dehydrogenase activity
OP701_RS15605	COG1653	transport
OP701_RS15610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OP701_RS15615	COG4209	transmembrane transport
OP701_RS15620	COG2207	Transcriptional regulator
OP701_RS15625	COG1653	transport
OP701_RS15630	COG0395	ABC-type sugar transport system, permease component
OP701_RS15635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS15640	COG2124	cytochrome p450
OP701_RS15645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OP701_RS15655	COG0156	8-amino-7-oxononanoate synthase activity
OP701_RS15660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OP701_RS15665	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OP701_RS15675	COG1073	alpha beta
OP701_RS15680	COG1609	Transcriptional regulator
OP701_RS15685	COG1653	transport
OP701_RS15690	COG1175	transmembrane transport
OP701_RS15695	COG0395	ABC-type sugar transport system, permease component
OP701_RS15700	COG1486	melibiose metabolic process
OP701_RS15705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OP701_RS15710	COG0495	leucyl-tRNA aminoacylation
OP701_RS15720	COG1366	Belongs to the anti-sigma-factor antagonist family
OP701_RS15720	COG2202	Pas domain
OP701_RS15725	COG2814	Major facilitator Superfamily
OP701_RS15730	COG2433	Pfam Transposase IS66
OP701_RS15735	COG0577	efflux transmembrane transporter activity
OP701_RS15740	COG1136	(ABC) transporter
OP701_RS15745	COG2205	protein histidine kinase activity
OP701_RS15750	COG0745	RESPONSE REGULATOR receiver
OP701_RS15755	COG0577	efflux transmembrane transporter activity
OP701_RS15760	COG1136	(ABC) transporter
OP701_RS15775	COG1131	(ABC) transporter
OP701_RS15780	COG1725	Transcriptional regulator
OP701_RS15795	COG1242	4 iron, 4 sulfur cluster binding
OP701_RS15800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OP701_RS15810	COG2267	carboxylic ester hydrolase activity
OP701_RS15815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OP701_RS15820	COG1113	amino acid transport
OP701_RS15825	COG0367	asparagine synthase
OP701_RS15830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OP701_RS15835	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OP701_RS15845	COG1506	peptidase
OP701_RS15850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OP701_RS15855	COG1116	anion transmembrane transporter activity
OP701_RS15860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OP701_RS15865	COG0494	nUDIX hydrolase
OP701_RS15870	COG4824	toxin secretion phage lysis holin
OP701_RS15875	COG0783	Belongs to the Dps family
OP701_RS15890	COG1854	S-ribosylhomocysteine lyase activity
OP701_RS15895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OP701_RS15900	COG0288	reversible hydration of carbon dioxide
OP701_RS15905	COG0254	rRNA binding
OP701_RS15910	COG1271	oxidase subunit
OP701_RS15915	COG1294	oxidase, subunit
OP701_RS15925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP701_RS15930	COG1321	iron dependent repressor
OP701_RS15930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP701_RS15935	COG1121	(ABC) transporter
OP701_RS15940	COG0803	Belongs to the bacterial solute-binding protein 9 family
OP701_RS15945	COG4948	Mandelate Racemase Muconate Lactonizing
OP701_RS15950	COG0318	PFAM AMP-dependent synthetase and ligase
OP701_RS15955	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OP701_RS15960	COG0596	Alpha beta hydrolase
OP701_RS15965	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OP701_RS15970	COG1169	isochorismate synthase
OP701_RS15975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OP701_RS15980	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OP701_RS15985	COG0058	SHG alpha-glucan phosphorylase activity
OP701_RS15990	COG0297	glycogen (starch) synthase activity
OP701_RS15995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OP701_RS16000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OP701_RS16005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OP701_RS16130	COG3859	Proton-coupled thiamine transporter YuaJ
OP701_RS16135	COG1247	-acetyltransferase
OP701_RS16140	COG2268	Band 7 protein
OP701_RS16145	COG1585	Membrane protein implicated in regulation of membrane protease activity
OP701_RS16150	COG2318	DinB family
OP701_RS16160	COG1454	alcohol dehydrogenase
OP701_RS16165	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS16170	COG1510	regulation of RNA biosynthetic process
OP701_RS16180	COG0569	domain protein
OP701_RS16185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OP701_RS16190	COG4682	membrane
OP701_RS16195	COG1705	Flagellar rod assembly protein muramidase FlgJ
OP701_RS16200	COG0477	Major facilitator Superfamily
OP701_RS16205	COG5553	Cysteine dioxygenase type I
OP701_RS16215	COG1968	undecaprenyl-diphosphatase activity
OP701_RS16220	COG0628	permease
OP701_RS16225	COG0673	inositol 2-dehydrogenase activity
OP701_RS16230	COG4806	L-rhamnose isomerase
OP701_RS16235	COG3254	rhamnose metabolic process
OP701_RS16240	COG1070	Carbohydrate kinase
OP701_RS16245	COG1349	DNA-binding transcription factor activity
OP701_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS16250	COG3347	Dehydrogenase
OP701_RS16255	COG0840	transmembrane signaling receptor activity
OP701_RS16260	COG0840	transmembrane signaling receptor activity
OP701_RS16270	COG0840	transmembrane signaling receptor activity
OP701_RS16285	COG2070	2-Nitropropane dioxygenase
OP701_RS16290	COG0432	Pfam Uncharacterised protein family UPF0047
OP701_RS16295	COG0366	Alpha amylase catalytic
OP701_RS16300	COG1253	flavin adenine dinucleotide binding
OP701_RS16305	COG2738	Putative neutral zinc metallopeptidase
OP701_RS16320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OP701_RS16335	COG0166	Belongs to the GPI family
OP701_RS16340	COG1979	alcohol dehydrogenase
OP701_RS16345	COG1979	alcohol dehydrogenase
OP701_RS16350	COG2155	Conserved Protein
OP701_RS16355	COG1098	S1 RNA binding domain
OP701_RS16360	COG0436	Aminotransferase
OP701_RS16365	COG1522	sequence-specific DNA binding
OP701_RS16370	COG2267	carboxylic ester hydrolase activity
OP701_RS16380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OP701_RS16385	COG2205	protein histidine kinase activity
OP701_RS16395	COG5018	Exonuclease
OP701_RS16405	COG2814	Major facilitator Superfamily
OP701_RS16410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OP701_RS16415	COG3011	Protein conserved in bacteria
OP701_RS16425	COG3290	protein histidine kinase activity
OP701_RS16430	COG4565	transcriptional regulatory protein
OP701_RS16435	COG1744	ABC transporter substrate-binding protein PnrA-like
OP701_RS16440	COG3845	ABC transporter
OP701_RS16445	COG4603	Belongs to the binding-protein-dependent transport system permease family
OP701_RS16450	COG1079	Belongs to the binding-protein-dependent transport system permease family
OP701_RS16455	COG3493	citrate carrier protein
OP701_RS16465	COG2111	Na H antiporter
OP701_RS16465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OP701_RS16470	COG2111	Na H antiporter
OP701_RS16475	COG1006	Multisubunit Na H antiporter MnhC subunit
OP701_RS16480	COG0651	ATP synthesis coupled electron transport
OP701_RS16485	COG1863	multisubunit Na H antiporter MnhE subunit
OP701_RS16490	COG2212	antiporter activity
OP701_RS16495	COG1320	monovalent cation:proton antiporter activity
OP701_RS16500	COG2050	protein possibly involved in aromatic compounds catabolism
OP701_RS16510	COG4585	Histidine kinase
OP701_RS16520	COG0142	geranyltranstransferase activity
OP701_RS16540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OP701_RS16545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OP701_RS16550	COG1335	isochorismatase
OP701_RS16555	COG5506	Protein of unknown function (DUF1694)
OP701_RS16570	COG0628	permease
OP701_RS16585	COG1418	mRNA catabolic process
OP701_RS16590	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS16600	COG1511	domain protein
OP701_RS16605	COG0433	COG0433 Predicted ATPase
OP701_RS16605	COG1674	ftsk spoiiie
OP701_RS16610	COG4499	WXG100 protein secretion system (Wss), protein YukC
OP701_RS16615	COG5417	Belongs to the EsaB family
OP701_RS16620	COG4842	Belongs to the WXG100 family
OP701_RS16625	COG2508	Transcriptional regulator
OP701_RS16625	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OP701_RS16630	COG0686	Belongs to the AlaDH PNT family
OP701_RS16635	COG5634	Uncharacterized conserved protein (DUF2278)
OP701_RS16640	COG3251	PFAM MbtH domain protein
OP701_RS16645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS16650	COG3433	isochorismatase activity
OP701_RS16650	COG1535	isochorismatase
OP701_RS16655	COG1021	2,3-dihydroxybenzoate-AMP ligase
OP701_RS16660	COG1169	isochorismate synthase
OP701_RS16665	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS16670	COG2819	hydrolase of the alpha beta superfamily
OP701_RS16675	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OP701_RS16680	COG1268	BioY protein
OP701_RS16685	COG2056	Na+-H+ antiporter family
OP701_RS16690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OP701_RS16695	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OP701_RS16700	COG3584	3D domain protein
OP701_RS16715	COG1252	NADH dehydrogenase
OP701_RS16720	COG0492	ferredoxin-NADP+ reductase activity
OP701_RS16730	COG0516	GMP reductase activity
OP701_RS16735	COG2808	Putative FMN-binding domain
OP701_RS16740	COG0456	acetyltransferase
OP701_RS16745	COG0316	Belongs to the HesB IscA family
OP701_RS16750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OP701_RS16755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OP701_RS16760	COG4844	belongs to the
OP701_RS16765	COG1252	NADH dehydrogenase
OP701_RS16770	COG4837	Protein of unknown function (DUF1462)
OP701_RS16775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OP701_RS16780	COG0823	Involved in the tonB-independent uptake of proteins
OP701_RS16780	COG1506	peptidase
OP701_RS16780	COG4946	Tricorn protease homolog
OP701_RS16785	COG0083	homoserine kinase activity
OP701_RS16790	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OP701_RS16795	COG0460	homoserine dehydrogenase
OP701_RS16800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OP701_RS16805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OP701_RS16810	COG0647	UMP catabolic process
OP701_RS16815	COG2445	Protein of unknown function DUF86
OP701_RS16820	COG4470	Protein conserved in bacteria
OP701_RS16830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OP701_RS16835	COG0739	heme binding
OP701_RS16845	COG3377	Domain of unknown function (DUF1805)
OP701_RS16850	COG0737	Belongs to the 5'-nucleotidase family
OP701_RS16855	COG0730	response to heat
OP701_RS16860	COG1801	Protein of unknown function DUF72
OP701_RS16870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OP701_RS16875	COG2508	Transcriptional regulator
OP701_RS16880	COG2233	PERMEase
OP701_RS16885	COG2233	PERMEase
OP701_RS16890	COG3195	allantoin biosynthetic process
OP701_RS16890	COG3648	Uricase
OP701_RS16895	COG2351	hydroxyisourate hydrolase activity
OP701_RS16920	COG2080	2 iron, 2 sulfur cluster binding
OP701_RS16925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OP701_RS16930	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OP701_RS16935	COG2068	MobA-Related Protein
OP701_RS16940	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OP701_RS16945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OP701_RS16950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OP701_RS16960	COG2356	endonuclease I
OP701_RS16965	COG3842	ATPase activity
OP701_RS16970	COG2188	Transcriptional regulator
OP701_RS16975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP701_RS16980	COG0395	ABC-type sugar transport system, permease component
OP701_RS16985	COG1175	transmembrane transport
OP701_RS16990	COG1653	transport
OP701_RS16995	COG2222	sugar isomerase
OP701_RS17000	COG0322	excinuclease ABC activity
OP701_RS17005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OP701_RS17020	COG0346	lactoylglutathione lyase activity
OP701_RS17025	COG0640	Transcriptional regulator
OP701_RS17030	COG0719	Fe-S assembly protein
OP701_RS17035	COG0822	iron-sulfur transferase activity
OP701_RS17040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OP701_RS17045	COG0719	Fe-S assembly protein
OP701_RS17050	COG0396	ATPase activity
OP701_RS17060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OP701_RS17065	COG1464	Belongs to the NlpA lipoprotein family
OP701_RS17070	COG2011	ABC-type metal ion transport system permease component
OP701_RS17075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OP701_RS17085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP701_RS17090	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OP701_RS17100	COG0509	glycine decarboxylation via glycine cleavage system
OP701_RS17105	COG1393	Belongs to the ArsC family
OP701_RS17110	COG1960	acyl-CoA dehydrogenase activity
OP701_RS17115	COG0183	Belongs to the thiolase family
OP701_RS17120	COG1250	3-hydroxyacyl-CoA dehydrogenase
OP701_RS17120	COG1024	Enoyl-CoA hydratase
OP701_RS17130	COG0506	proline dehydrogenase activity
OP701_RS17140	COG5577	PFAM Coat F domain
OP701_RS17145	COG1846	Transcriptional regulator
OP701_RS17150	COG0477	Major facilitator Superfamily
OP701_RS17155	COG1942	4-Oxalocrotonate Tautomerase
OP701_RS17160	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS17165	COG0583	DNA-binding transcription factor activity
OP701_RS17175	COG1120	ATPase activity
OP701_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS17195	COG0783	Belongs to the Dps family
OP701_RS17200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP701_RS17205	COG0745	RESPONSE REGULATOR receiver
OP701_RS17210	COG2205	protein histidine kinase activity
OP701_RS17210	COG2770	Histidine kinase
OP701_RS17220	COG1309	transcriptional regulator
OP701_RS17225	COG0114	fumarate hydratase activity
OP701_RS17235	COG0697	spore germination
OP701_RS17240	COG0814	amino acid
OP701_RS17250	COG2197	response regulator
OP701_RS17255	COG4585	Histidine kinase
OP701_RS17260	COG4758	membrane
OP701_RS17265	COG3595	metallopeptidase activity
OP701_RS17270	COG1842	Phage shock protein A
OP701_RS17275	COG4758	membrane
OP701_RS17280	COG2814	Major facilitator Superfamily
OP701_RS17285	COG2096	Adenosyltransferase
OP701_RS17290	COG1120	ATPase activity
OP701_RS17295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS17300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP701_RS17305	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS17310	COG3386	PFAM SMP-30 Gluconolaconase
OP701_RS17315	COG2205	protein histidine kinase activity
OP701_RS17320	COG0745	RESPONSE REGULATOR receiver
OP701_RS17330	COG1191	sigma factor activity
OP701_RS17340	COG2140	Oxalate decarboxylase
OP701_RS17350	COG0577	efflux transmembrane transporter activity
OP701_RS17355	COG1136	(ABC) transporter
OP701_RS17360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP701_RS17365	COG1120	ATPase activity
OP701_RS17370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS17375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP701_RS17380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP701_RS17385	COG0640	Transcriptional regulator
OP701_RS17400	COG0531	amino acid
OP701_RS17410	COG1988	membrane-bound metal-dependent
OP701_RS17415	COG1368	sulfuric ester hydrolase activity
OP701_RS17420	COG1910	domain protein
OP701_RS17425	COG0725	ABC transporter, periplasmic molybdate-binding protein
OP701_RS17430	COG4149	molybdate abc transporter
OP701_RS17435	COG0656	L-ascorbic acid biosynthetic process
OP701_RS17445	COG0025	NhaP-type Na H and K H
OP701_RS17450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OP701_RS17455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OP701_RS17460	COG3973	AAA domain
OP701_RS17465	COG2860	membrane
OP701_RS17470	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OP701_RS17475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OP701_RS17480	COG2217	Heavy metal translocating P-type atpase
OP701_RS17485	COG2217	Heavy metal translocating P-type atpase
OP701_RS17490	COG2608	mercury ion transmembrane transporter activity
OP701_RS17495	COG1937	Protein conserved in bacteria
OP701_RS17500	COG0673	inositol 2-dehydrogenase activity
OP701_RS17505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OP701_RS17510	COG1289	transmembrane transporter activity
OP701_RS17525	COG2076	Multidrug Resistance protein
OP701_RS17530	COG1309	transcriptional regulator
OP701_RS17535	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS17555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OP701_RS17560	COG0557	exoribonuclease II activity
OP701_RS17565	COG1647	Serine aminopeptidase, S33
OP701_RS17570	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OP701_RS17575	COG0596	Alpha beta hydrolase
OP701_RS17580	COG1476	TRANSCRIPTIONal
OP701_RS17585	COG1396	sequence-specific DNA binding
OP701_RS17590	COG1396	sequence-specific DNA binding
OP701_RS17595	COG1733	regulation of RNA biosynthetic process
OP701_RS17600	COG0840	transmembrane signaling receptor activity
OP701_RS17605	COG1174	glycine betaine transport
OP701_RS17610	COG1732	Glycine betaine
OP701_RS17615	COG1174	glycine betaine transport
OP701_RS17620	COG0517	IMP dehydrogenase activity
OP701_RS17620	COG1125	glycine betaine transport
OP701_RS17625	COG1510	regulation of RNA biosynthetic process
OP701_RS17630	COG1174	glycine betaine transport
OP701_RS17635	COG1732	Glycine betaine
OP701_RS17640	COG1174	glycine betaine transport
OP701_RS17645	COG0517	IMP dehydrogenase activity
OP701_RS17645	COG1125	glycine betaine transport
OP701_RS17650	COG1510	regulation of RNA biosynthetic process
OP701_RS17660	COG3064	Membrane
OP701_RS17665	COG4640	response to antibiotic
OP701_RS17670	COG0456	acetyltransferase
OP701_RS17680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OP701_RS17690	COG0126	phosphoglycerate kinase activity
OP701_RS17695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OP701_RS17700	COG2390	Transcriptional regulator
OP701_RS17705	COG2814	Major facilitator Superfamily
OP701_RS17710	COG1609	Transcriptional regulator
OP701_RS17715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS17720	COG0583	DNA-binding transcription factor activity
OP701_RS17725	COG0697	spore germination
OP701_RS17730	COG1113	amino acid transport
OP701_RS17735	COG3858	chitin binding
OP701_RS17740	COG1556	Lactate utilization protein
OP701_RS17745	COG1139	Iron-sulfur cluster binding protein
OP701_RS17750	COG0247	lactate metabolic process
OP701_RS17755	COG2197	response regulator
OP701_RS17760	COG4585	Histidine kinase
OP701_RS17765	COG0842	Transport permease protein
OP701_RS17770	COG1131	(ABC) transporter
OP701_RS17775	COG0596	Alpha beta hydrolase
OP701_RS17780	COG2208	phosphoserine phosphatase activity
OP701_RS17785	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OP701_RS17790	COG1874	Beta-galactosidase
OP701_RS17795	COG3833	ABC-type maltose transport systems, permease component
OP701_RS17800	COG1175	transmembrane transport
OP701_RS17805	COG2182	Extracellular solute-binding protein
OP701_RS17810	COG1609	Transcriptional regulator
OP701_RS17815	COG2186	Transcriptional regulator
OP701_RS17820	COG1620	l-lactate permease
OP701_RS17825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OP701_RS17835	COG5039	Polysaccharide pyruvyl transferase
OP701_RS17840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OP701_RS17845	COG0110	maltose O-acetyltransferase activity
OP701_RS17850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OP701_RS17855	COG2244	polysaccharide biosynthetic process
OP701_RS17860	COG1216	Glycosyl transferase, family 2
OP701_RS17865	COG5039	Polysaccharide pyruvyl transferase
OP701_RS17870	COG1216	Glycosyl transferase, family 2
OP701_RS17880	COG0438	transferase activity, transferring glycosyl groups
OP701_RS17885	COG1215	transferase activity, transferring glycosyl groups
OP701_RS17890	COG0438	transferase activity, transferring glycosyl groups
OP701_RS17895	COG1086	Polysaccharide biosynthesis protein
OP701_RS17900	COG0489	protein tyrosine kinase activity
OP701_RS17905	COG3944	biosynthesis protein
OP701_RS17910	COG1396	sequence-specific DNA binding
OP701_RS17915	COG2272	Belongs to the type-B carboxylesterase lipase family
OP701_RS17925	COG3479	Phenolic acid decarboxylase
OP701_RS17935	COG1794	racemase activity, acting on amino acids and derivatives
OP701_RS17940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OP701_RS17950	COG1621	beta-fructofuranosidase activity
OP701_RS17955	COG1621	beta-fructofuranosidase activity
OP701_RS17960	COG0531	amino acid
OP701_RS17965	COG1309	transcriptional regulator
OP701_RS17970	COG2076	Multidrug Resistance protein
OP701_RS17975	COG2076	Multidrug Resistance protein
OP701_RS17995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OP701_RS18000	COG0366	Alpha amylase catalytic
OP701_RS18005	COG1554	hydrolase, family 65, central catalytic
OP701_RS18015	COG3833	ABC-type maltose transport systems, permease component
OP701_RS18020	COG1175	transmembrane transport
OP701_RS18025	COG2182	Extracellular solute-binding protein
OP701_RS18030	COG0366	Alpha amylase catalytic
OP701_RS18035	COG1609	Transcriptional regulator
OP701_RS18040	COG1611	Belongs to the LOG family
OP701_RS18045	COG1694	Mazg nucleotide pyrophosphohydrolase
OP701_RS18050	COG0659	secondary active sulfate transmembrane transporter activity
OP701_RS18055	COG0288	reversible hydration of carbon dioxide
OP701_RS18060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OP701_RS18065	COG0577	efflux transmembrane transporter activity
OP701_RS18070	COG1136	(ABC) transporter
OP701_RS18075	COG5002	protein histidine kinase activity
OP701_RS18080	COG0745	RESPONSE REGULATOR receiver
OP701_RS18090	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OP701_RS18095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS18100	COG1481	regulation of sporulation
OP701_RS18105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OP701_RS18110	COG1660	Displays ATPase and GTPase activities
OP701_RS18115	COG1051	belongs to the nudix hydrolase family
OP701_RS18120	COG0492	ferredoxin-NADP+ reductase activity
OP701_RS18125	COG3883	PFAM NLP P60 protein
OP701_RS18125	COG0791	NLP P60 protein
OP701_RS18130	COG0457	Tetratricopeptide repeat
OP701_RS18135	COG1132	(ABC) transporter
OP701_RS18155	COG0140	phosphoribosyl-ATP diphosphatase activity
OP701_RS18155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OP701_RS18160	COG0107	imidazoleglycerol-phosphate synthase activity
OP701_RS18165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OP701_RS18170	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OP701_RS18175	COG0131	Imidazoleglycerol-phosphate dehydratase
OP701_RS18180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OP701_RS18185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OP701_RS18190	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OP701_RS18195	COG4990	cell redox homeostasis
OP701_RS18200	COG5297	Belongs to the glycosyl hydrolase family 6
OP701_RS18205	COG0110	maltose O-acetyltransferase activity
OP701_RS18210	COG0546	phosphoglycolate phosphatase activity
OP701_RS18215	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OP701_RS18220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OP701_RS18225	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OP701_RS18230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OP701_RS18235	COG0363	glucosamine-6-phosphate deaminase activity
OP701_RS18240	COG2188	Transcriptional regulator
OP701_RS18245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OP701_RS18250	COG1846	Transcriptional regulator
OP701_RS18255	COG2814	Major facilitator Superfamily
OP701_RS18265	COG1950	PFAM Membrane protein of
OP701_RS18270	COG1983	PspC domain protein
OP701_RS18275	COG3595	metallopeptidase activity
OP701_RS18290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OP701_RS18295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OP701_RS18300	COG0556	nucleotide-excision repair
OP701_RS18305	COG4897	Protein conserved in bacteria
OP701_RS18315	COG3848	Pyruvate phosphate dikinase
OP701_RS18315	COG0574	Belongs to the PEP-utilizing enzyme family
OP701_RS18320	COG1309	transcriptional regulator
OP701_RS18325	COG2814	Major facilitator Superfamily
OP701_RS18330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP701_RS18340	COG0793	Belongs to the peptidase S41A family
OP701_RS18340	COG3409	Peptidoglycan-binding domain 1 protein
OP701_RS18345	COG2177	Part of the ABC transporter FtsEX involved in
OP701_RS18350	COG2884	Cell division ATP-binding protein ftsE
OP701_RS18355	COG2010	Cytochrome c
OP701_RS18360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS18370	COG0653	protein targeting
OP701_RS18375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OP701_RS18390	COG1516	flagellar protein fliS
OP701_RS18395	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OP701_RS18400	COG1334	flagellar protein FlaG
OP701_RS18405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OP701_RS18410	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OP701_RS18415	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OP701_RS18425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OP701_RS18430	COG1256	bacterial-type flagellum assembly
OP701_RS18430	COG4786	Flagellar basal body rod
OP701_RS18435	COG3418	PFAM FlgN family protein
OP701_RS18440	COG2747	anti-sigma28 factor FlgM
OP701_RS18450	COG1040	competence protein
OP701_RS18460	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OP701_RS18465	COG1307	EDD domain protein, DegV family
OP701_RS18470	COG2197	response regulator
OP701_RS18475	COG4585	Histidine kinase
OP701_RS18480	COG1739	Uncharacterized protein family UPF0029
OP701_RS18485	COG1316	TRANSCRIPTIONal
OP701_RS18490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OP701_RS18495	COG0438	transferase activity, transferring glycosyl groups
OP701_RS18500	COG1215	transferase activity, transferring glycosyl groups
OP701_RS18505	COG3206	protein involved in exopolysaccharide biosynthesis
OP701_RS18510	COG3307	-O-antigen
OP701_RS18515	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OP701_RS18520	COG0297	glycogen (starch) synthase activity
OP701_RS18520	COG0438	transferase activity, transferring glycosyl groups
OP701_RS18525	COG2244	polysaccharide biosynthetic process
OP701_RS18540	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP701_RS18540	COG2247	cell wall binding repeat
OP701_RS18545	COG2247	cell wall binding repeat
OP701_RS18545	COG2385	sporulation resulting in formation of a cellular spore
OP701_RS18555	COG1316	TRANSCRIPTIONal
OP701_RS18560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OP701_RS18585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OP701_RS18590	COG1134	teichoic acid transport
OP701_RS18595	COG1682	transport, permease protein
OP701_RS18600	COG1215	transferase activity, transferring glycosyl groups
OP701_RS18610	COG1181	Belongs to the D-alanine--D-alanine ligase family
OP701_RS18615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OP701_RS18615	COG0463	Glycosyl transferase, family 2
OP701_RS18625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OP701_RS18635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OP701_RS18670	COG4193	domain, Protein
OP701_RS18675	COG1482	cell wall glycoprotein biosynthetic process
OP701_RS18680	COG0697	spore germination
OP701_RS18685	COG0814	amino acid
OP701_RS18695	COG2814	Major facilitator Superfamily
OP701_RS18700	COG1316	TRANSCRIPTIONal
OP701_RS18705	COG0561	phosphatase activity
OP701_RS18710	COG0791	NLP P60 protein
OP701_RS18720	COG2843	Capsule synthesis protein
OP701_RS18730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OP701_RS18735	COG1609	Transcriptional regulator
OP701_RS18740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP701_RS18745	COG1869	D-ribose catabolic process
OP701_RS18750	COG1129	ABC transporter
OP701_RS18755	COG1172	Belongs to the binding-protein-dependent transport system permease family
OP701_RS18760	COG1879	ABC-type sugar transport system periplasmic component
OP701_RS18765	COG3103	Sh3 type 3 domain protein
OP701_RS18775	COG2249	NAD(P)H dehydrogenase (quinone) activity
OP701_RS18780	COG3527	Alpha-acetolactate decarboxylase
OP701_RS18785	COG0028	Belongs to the TPP enzyme family
OP701_RS18790	COG0583	DNA-binding transcription factor activity
OP701_RS18795	COG5337	Spore coat protein CotH
OP701_RS18805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OP701_RS18815	COG0405	Gamma-glutamyltransferase
OP701_RS18820	COG1522	sequence-specific DNA binding
OP701_RS18825	COG2059	Chromate
OP701_RS18830	COG2059	Chromate
OP701_RS18840	COG0655	NAD(P)H dehydrogenase (quinone) activity
OP701_RS18845	COG0583	DNA-binding transcription factor activity
OP701_RS18865	COG5444	nuclease activity
OP701_RS18880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OP701_RS18885	COG4464	protein tyrosine phosphatase activity
OP701_RS18890	COG0489	protein tyrosine kinase activity
OP701_RS18895	COG3944	biosynthesis protein
OP701_RS18905	COG4715	Zinc finger, swim domain protein
OP701_RS18910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OP701_RS18915	COG0561	phosphatase activity
OP701_RS18920	COG1349	DNA-binding transcription factor activity
OP701_RS18925	COG0629	single-stranded DNA binding
OP701_RS18940	COG2602	Beta-lactamase
OP701_RS18945	COG3764	Sortase (surface protein transpeptidase)
OP701_RS18955	COG3279	Response regulator of the LytR AlgR family
OP701_RS18965	COG0745	RESPONSE REGULATOR receiver
OP701_RS18965	COG2972	Histidine kinase
OP701_RS18970	COG1970	mechanosensitive ion channel activity
OP701_RS18975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OP701_RS18980	COG0457	Tetratricopeptide repeat
OP701_RS18985	COG4786	Flagellar basal body rod
OP701_RS18990	COG4786	Flagellar basal body rod
OP701_RS18995	COG1077	Cell shape determining protein MreB Mrl
OP701_RS19000	COG1609	Transcriptional regulator
OP701_RS19010	COG1846	Transcriptional regulator
OP701_RS19015	COG2814	Major facilitator Superfamily
OP701_RS19020	COG3420	alginic acid biosynthetic process
OP701_RS19025	COG1953	Uracil, thiamine, allantoin
OP701_RS19030	COG0477	Major facilitator Superfamily
OP701_RS19035	COG1335	isochorismatase
OP701_RS19045	COG0004	ammonium transporteR
OP701_RS19050	COG0347	Belongs to the P(II) protein family
OP701_RS19055	COG0671	phosphoesterase, PA-phosphatase related
OP701_RS19065	COG0739	heme binding
OP701_RS19070	COG1247	-acetyltransferase
OP701_RS19080	COG1086	Polysaccharide biosynthesis protein
OP701_RS19085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP701_RS19090	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OP701_RS19095	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OP701_RS19110	COG2089	acid synthase
OP701_RS19120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OP701_RS19125	COG0789	Transcriptional regulator
OP701_RS19135	COG2910	NAD(P)H-binding
OP701_RS19140	COG1959	2 iron, 2 sulfur cluster binding
OP701_RS19145	COG0804	urea catabolic process
OP701_RS19150	COG0832	Belongs to the urease beta subunit family
OP701_RS19155	COG0831	urea catabolic process
OP701_RS19185	COG3237	CsbD-like
OP701_RS19190	COG1994	Peptidase M50
OP701_RS19195	COG0457	Tetratricopeptide repeat
OP701_RS19200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OP701_RS19205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OP701_RS19215	COG2304	oxidoreductase activity
OP701_RS19220	COG2304	oxidoreductase activity
OP701_RS19225	COG2385	sporulation resulting in formation of a cellular spore
OP701_RS19230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OP701_RS19240	COG4836	Membrane
OP701_RS19255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OP701_RS19260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OP701_RS19265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OP701_RS19270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OP701_RS19275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OP701_RS19285	COG0356	it plays a direct role in the translocation of protons across the membrane
OP701_RS19295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OP701_RS19300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OP701_RS19305	COG4475	Protein of unknown function (DUF436)
OP701_RS19310	COG0698	ribose 5-phosphate isomerase
OP701_RS19315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OP701_RS19320	COG1971	Probably functions as a manganese efflux pump
OP701_RS19325	COG0009	L-threonylcarbamoyladenylate synthase
OP701_RS19330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OP701_RS19350	COG2890	protein-(glutamine-N5) methyltransferase activity
OP701_RS19355	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OP701_RS19360	COG0346	lactoylglutathione lyase activity
OP701_RS19365	COG0789	Transcriptional regulator
OP701_RS19370	COG0679	Auxin Efflux Carrier
OP701_RS19375	COG0281	malic enzyme
OP701_RS19380	COG1435	thymidine kinase activity
OP701_RS19390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OP701_RS19400	COG1494	fructose-1,6-bisphosphatase
OP701_RS19405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OP701_RS19410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OP701_RS19415	COG0191	fructose-bisphosphate aldolase activity
OP701_RS19420	COG2204	response regulator
OP701_RS19425	COG4821	SIS domain
OP701_RS19430	COG0504	CTP synthase activity
OP701_RS19435	COG3343	RNA polymerase activity
OP701_RS19440	COG1960	acyl-CoA dehydrogenase activity
OP701_RS19445	COG0247	lactate metabolic process
OP701_RS19445	COG2181	nitrate reductase activity
OP701_RS19450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OP701_RS19455	COG4294	response to UV
OP701_RS19465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OP701_RS19470	COG1132	(ABC) transporter
OP701_RS19475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OP701_RS19485	COG2181	nitrate reductase activity
OP701_RS19490	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OP701_RS19495	COG1140	nitrate reductase beta subunit
OP701_RS19500	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OP701_RS19505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OP701_RS19515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OP701_RS19520	COG2223	nitrite transmembrane transporter activity
OP701_RS19525	COG0018	arginyl-trna synthetase
OP701_RS19530	COG4506	Protein conserved in bacteria
OP701_RS19545	COG0535	radical SAM domain protein
OP701_RS19555	COG1131	(ABC) transporter
OP701_RS19565	COG0612	Peptidase, M16
OP701_RS19580	COG3391	amine dehydrogenase activity
OP701_RS19585	COG3391	amine dehydrogenase activity
OP701_RS19590	COG0457	Tetratricopeptide repeat
OP701_RS19605	COG0010	Belongs to the arginase family
OP701_RS19610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OP701_RS19615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OP701_RS19625	COG1994	Peptidase M50
OP701_RS19630	COG1942	4-Oxalocrotonate Tautomerase
OP701_RS19635	COG1846	Transcriptional regulator
OP701_RS19640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OP701_RS19655	COG1959	2 iron, 2 sulfur cluster binding
OP701_RS19660	COG3465	dGTPase activity
OP701_RS19665	COG1078	dGTPase activity
OP701_RS19670	COG4844	belongs to the
OP701_RS19680	COG0697	spore germination
OP701_RS19690	COG0095	Lipoate-protein ligase
OP701_RS19695	COG0583	DNA-binding transcription factor activity
OP701_RS19700	COG0280	phosphate acetyltransferase
OP701_RS19705	COG3253	May function as heme-dependent peroxidase
OP701_RS19710	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS19715	COG0436	Aminotransferase
OP701_RS19720	COG2814	Major facilitator Superfamily
OP701_RS19725	COG0151	Belongs to the GarS family
OP701_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS19735	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS19740	COG0077	Prephenate dehydratase
OP701_RS19745	COG2814	Major facilitator Superfamily
OP701_RS19750	COG0833	amino acid
OP701_RS19755	COG4187	Peptidase family M20/M25/M40
OP701_RS19760	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS19765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OP701_RS19775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OP701_RS19780	COG1091	dTDP-4-dehydrorhamnose reductase activity
OP701_RS19785	COG1088	dTDP-glucose 4,6-dehydratase activity
OP701_RS19790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OP701_RS19800	COG0456	acetyltransferase
OP701_RS19815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OP701_RS19820	COG0463	Glycosyl transferase, family 2
OP701_RS19830	COG2363	Small membrane protein
OP701_RS19835	COG2233	PERMEase
OP701_RS19845	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS19850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OP701_RS19855	COG1216	Glycosyl transferase, family 2
OP701_RS19860	COG0351	phosphomethylpyrimidine kinase
OP701_RS19870	COG1621	beta-fructofuranosidase activity
OP701_RS19875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS19875	COG1263	PTS System
OP701_RS19880	COG2116	formate transmembrane transporter activity
OP701_RS19885	COG3711	transcriptional antiterminator
OP701_RS19895	COG1404	Belongs to the peptidase S8 family
OP701_RS19900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS19905	COG0778	Nitroreductase
OP701_RS19910	COG0772	Belongs to the SEDS family
OP701_RS19935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OP701_RS19940	COG2261	transglycosylase associated protein
OP701_RS19945	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OP701_RS19950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OP701_RS19955	COG2246	polysaccharide biosynthetic process
OP701_RS19960	COG1309	transcriptional regulator
OP701_RS19970	COG3162	membrane
OP701_RS19975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OP701_RS19980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OP701_RS19985	COG2837	iron assimilation
OP701_RS19990	COG2822	iron ion transport
OP701_RS19995	COG0672	)-iron permease
OP701_RS20000	COG0352	thiamine-phosphate diphosphorylase activity
OP701_RS20005	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OP701_RS20010	COG0583	DNA-binding transcription factor activity
OP701_RS20015	COG1380	Effector of murein hydrolase LrgA
OP701_RS20020	COG1346	cytolysis
OP701_RS20030	COG4895	conserved protein (DUF2196)
OP701_RS20035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OP701_RS20040	COG0346	lactoylglutathione lyase activity
OP701_RS20050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP701_RS20055	COG1404	Belongs to the peptidase S8 family
OP701_RS20060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS20060	COG1263	PTS System
OP701_RS20065	COG3711	transcriptional antiterminator
OP701_RS20070	COG1442	glycosyl transferase family 8
OP701_RS20075	COG5522	Integral membrane protein (intg_mem_TP0381)
OP701_RS20080	COG1846	Transcriptional regulator
OP701_RS20090	COG2234	aminopeptidase activity
OP701_RS20105	COG2814	Major facilitator Superfamily
OP701_RS20110	COG2357	RelA SpoT domain protein
OP701_RS20115	COG1575	Belongs to the MenA family. Type 1 subfamily
OP701_RS20130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP701_RS20135	COG1696	Membrane protein involved in D-alanine export
OP701_RS20140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OP701_RS20145	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OP701_RS20150	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OP701_RS20155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OP701_RS20160	COG1486	melibiose metabolic process
OP701_RS20165	COG1447	Phosphotransferase system cellobiose-specific component IIA
OP701_RS20170	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP701_RS20175	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP701_RS20180	COG3711	transcriptional antiterminator
OP701_RS20180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP701_RS20190	COG2094	Belongs to the DNA glycosylase MPG family
OP701_RS20195	COG0753	catalase activity
OP701_RS20200	COG2814	Major facilitator Superfamily
OP701_RS20205	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OP701_RS20210	COG1131	(ABC) transporter
OP701_RS20230	COG1595	DNA-templated transcription, initiation
OP701_RS20235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OP701_RS20240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OP701_RS20245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OP701_RS20250	COG4988	ABC transporter
OP701_RS20255	COG1294	oxidase, subunit
OP701_RS20260	COG1271	oxidase subunit
OP701_RS20265	COG3493	citrate carrier protein
OP701_RS20275	COG0726	polysaccharide deacetylase
OP701_RS20285	COG3842	ATPase activity
OP701_RS20290	COG2508	Transcriptional regulator
OP701_RS20295	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS20300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OP701_RS20310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OP701_RS20320	COG4585	Histidine kinase
OP701_RS20325	COG2197	response regulator
OP701_RS20330	COG2195	Cleaves the N-terminal amino acid of tripeptides
OP701_RS20345	COG4894	glucomannan catabolic process
OP701_RS20355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OP701_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS20365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OP701_RS20370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OP701_RS20375	COG2610	gluconate transmembrane transporter activity
OP701_RS20380	COG0500	methyltransferase
OP701_RS20385	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OP701_RS20400	COG0753	catalase activity
OP701_RS20400	COG0693	protein deglycase activity
OP701_RS20405	COG2851	Citrate transporter
OP701_RS20410	COG2273	Hydrolase Family 16
OP701_RS20415	COG2723	6-phospho-beta-galactosidase activity
OP701_RS20420	COG2190	(PTS) system
OP701_RS20420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS20420	COG1263	PTS System
OP701_RS20425	COG3711	transcriptional antiterminator
OP701_RS20435	COG2270	Major facilitator Superfamily
OP701_RS20440	COG0513	Belongs to the DEAD box helicase family
OP701_RS20445	COG3401	FG-GAP repeat protein
OP701_RS20445	COG2755	lipolytic protein G-D-S-L family
OP701_RS20465	COG0697	spore germination
OP701_RS20535	COG0697	spore germination
OP701_RS20545	COG0861	Integral membrane protein TerC family
OP701_RS20550	COG0589	response to stress
OP701_RS20555	COG2723	6-phospho-beta-galactosidase activity
OP701_RS20560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS20560	COG2190	(PTS) system
OP701_RS20560	COG1263	PTS System
OP701_RS20595	COG5444	nuclease activity
OP701_RS20630	COG3507	Belongs to the glycosyl hydrolase 43 family
OP701_RS20645	COG2986	histidine ammonia-lyase
OP701_RS20650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OP701_RS20655	COG1228	amidohydrolase
OP701_RS20660	COG0010	Belongs to the arginase family
OP701_RS20665	COG0833	amino acid
OP701_RS20670	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OP701_RS20675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OP701_RS20680	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OP701_RS20685	COG2390	Transcriptional regulator
OP701_RS20695	COG3192	ethanolamine utilization protein
OP701_RS20700	COG2079	MmgE PrpD family protein
OP701_RS20705	COG1473	amidohydrolase
OP701_RS20710	COG1126	abc transporter atp-binding protein
OP701_RS20715	COG0765	amino acid transport
OP701_RS20720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP701_RS20725	COG0456	acetyltransferase
OP701_RS20730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP701_RS20735	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OP701_RS20740	COG0561	phosphatase activity
OP701_RS20770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP701_RS20775	COG5294	Protein conserved in bacteria
OP701_RS20780	COG0577	efflux transmembrane transporter activity
OP701_RS20785	COG1136	(ABC) transporter
OP701_RS20790	COG2205	protein histidine kinase activity
OP701_RS20795	COG0745	RESPONSE REGULATOR receiver
OP701_RS20800	COG0191	fructose-bisphosphate aldolase activity
OP701_RS20805	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS20810	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS20815	COG0673	inositol 2-dehydrogenase activity
OP701_RS20820	COG2814	Major facilitator Superfamily
OP701_RS20825	COG1082	Xylose isomerase domain protein TIM barrel
OP701_RS20830	COG3962	Belongs to the TPP enzyme family
OP701_RS20835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP701_RS20845	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS20850	COG1349	DNA-binding transcription factor activity
OP701_RS20855	COG0667	Aldo Keto reductase
OP701_RS20870	COG2271	Major facilitator Superfamily
OP701_RS20890	COG2814	Major facilitator Superfamily
OP701_RS20895	COG0326	Molecular chaperone. Has ATPase activity
OP701_RS20905	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS20910	COG1309	transcriptional regulator
OP701_RS20915	COG1012	belongs to the aldehyde dehydrogenase family
OP701_RS20925	COG0667	Aldo Keto reductase
OP701_RS20930	COG0789	Transcriptional regulator
OP701_RS20935	COG1714	RDD family
OP701_RS20940	COG2311	Membrane
OP701_RS20945	COG1917	Cupin 2, conserved barrel domain protein
OP701_RS20950	COG1309	transcriptional regulator
OP701_RS20955	COG1028	Short-chain dehydrogenase reductase Sdr
OP701_RS20960	COG1846	Transcriptional regulator
OP701_RS20965	COG1380	Effector of murein hydrolase LrgA
OP701_RS20970	COG1346	cytolysis
OP701_RS20990	COG5039	Polysaccharide pyruvyl transferase
OP701_RS20995	COG1929	Belongs to the glycerate kinase type-1 family
OP701_RS21000	COG1802	Transcriptional regulator
OP701_RS21005	COG1070	Carbohydrate kinase
OP701_RS21010	COG2610	gluconate transmembrane transporter activity
OP701_RS21015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OP701_RS21020	COG0450	alkyl hydroperoxide reductase
OP701_RS21025	COG3634	alkyl hydroperoxide reductase activity
OP701_RS21035	COG2723	6-phospho-beta-galactosidase activity
OP701_RS21040	COG2190	(PTS) system
OP701_RS21040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP701_RS21040	COG1263	PTS System
OP701_RS21045	COG2188	Transcriptional regulator
OP701_RS21050	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
OP701_RS21065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OP701_RS21080	COG1063	alcohol dehydrogenase
OP701_RS21100	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OP701_RS21105	COG0456	acetyltransferase
OP701_RS21110	COG0457	Tetratricopeptide repeat
OP701_RS21120	COG0010	Belongs to the arginase family
OP701_RS21125	COG0833	amino acid
OP701_RS21130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OP701_RS21135	COG3829	transcription factor binding
OP701_RS21140	COG5002	protein histidine kinase activity
OP701_RS21145	COG0745	RESPONSE REGULATOR receiver
OP701_RS21165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP701_RS21170	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OP701_RS21175	COG4853	Protein conserved in bacteria
OP701_RS21180	COG4863	YycH protein
OP701_RS21185	COG5002	protein histidine kinase activity
OP701_RS21190	COG0745	RESPONSE REGULATOR receiver
OP701_RS21220	COG0346	lactoylglutathione lyase activity
OP701_RS21225	COG0305	Participates in initiation and elongation during chromosome replication
OP701_RS21240	COG3093	addiction module antidote protein HigA
OP701_RS21245	COG2807	transmembrane transport
OP701_RS21250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OP701_RS21255	COG0359	binds to the 23S rRNA
OP701_RS21260	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OP701_RS21265	COG4241	membrane
OP701_RS21275	COG5577	PFAM Coat F domain
OP701_RS21280	COG1733	regulation of RNA biosynthetic process
OP701_RS21285	COG1227	inorganic diphosphatase activity
OP701_RS21295	COG2271	Major facilitator Superfamily
OP701_RS21305	COG4319	ketosteroid isomerase
OP701_RS21310	COG1357	PFAM Pentapeptide repeats (8 copies)
OP701_RS21315	COG2814	Major facilitator Superfamily
OP701_RS21320	COG0583	DNA-binding transcription factor activity
OP701_RS21325	COG2153	protein acetylation
OP701_RS21335	COG0583	DNA-binding transcription factor activity
OP701_RS21355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP701_RS21360	COG1733	regulation of RNA biosynthetic process
OP701_RS21365	COG1846	Transcriptional regulator
OP701_RS21370	COG2153	protein acetylation
OP701_RS21375	COG2364	Membrane
OP701_RS21395	COG2315	Protein conserved in bacteria
OP701_RS21405	COG0789	Transcriptional regulator
OP701_RS21425	COG2856	Zn peptidase
OP701_RS21435	COG1331	Highly conserved protein containing a thioredoxin domain
OP701_RS21440	COG1266	CAAX protease self-immunity
OP701_RS21445	COG0477	Major facilitator Superfamily
OP701_RS21445	COG2814	Major facilitator Superfamily
OP701_RS21450	COG0346	lactoylglutathione lyase activity
OP701_RS21455	COG1609	Transcriptional regulator
OP701_RS21460	COG0708	Exodeoxyribonuclease III
OP701_RS21465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OP701_RS21470	COG0629	single-stranded DNA binding
OP701_RS21475	COG0360	Binds together with S18 to 16S ribosomal RNA
OP701_RS21480	COG0012	GTP binding
OP701_RS21485	COG0243	molybdopterin cofactor binding
OP701_RS21490	COG4481	Protein conserved in bacteria
OP701_RS21495	COG3949	Membrane
OP701_RS21510	COG1475	DNA binding
OP701_RS21515	COG1192	Involved in chromosome partitioning
OP701_RS21525	COG1475	DNA binding
OP701_RS21530	COG0357	Ribosomal RNA small subunit methyltransferase G
OP701_RS21535	COG0445	tRNA wobble uridine modification
OP701_RS21540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OP701_RS21545	COG1847	R3H domain protein
OP701_RS21550	COG0706	membrane insertase activity
OP701_RS21555	COG0594	ribonuclease P activity