locus-tag	class	description
AN935_RS00005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS00015	COG0517	IMP dehydrogenase activity
AN935_RS00015	COG0516	GMP reductase activity
AN935_RS00020	COG1686	Belongs to the peptidase S11 family
AN935_RS00030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AN935_RS00035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AN935_RS00045	COG1428	Deoxynucleoside kinase
AN935_RS00050	COG1428	Deoxynucleoside kinase
AN935_RS00055	COG3858	chitin binding
AN935_RS00055	COG1388	LysM domain
AN935_RS00060	COG1335	isochorismatase
AN935_RS00065	COG0590	tRNA wobble adenosine to inosine editing
AN935_RS00075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AN935_RS00080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AN935_RS00085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN935_RS00105	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
AN935_RS00110	COG3853	Toxic anion resistance protein (TelA)
AN935_RS00115	COG1982	Orn Lys Arg decarboxylase major
AN935_RS00120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AN935_RS00125	COG3870	Protein conserved in bacteria
AN935_RS00130	COG1728	Protein conserved in bacteria
AN935_RS00135	COG0470	DNA polymerase III
AN935_RS00140	COG1774	PSP1 C-terminal conserved region
AN935_RS00145	COG4467	Involved in initiation control of chromosome replication
AN935_RS00150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AN935_RS00155	COG2827	Endonuclease containing a URI domain
AN935_RS00160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AN935_RS00165	COG2002	toxin-antitoxin pair type II binding
AN935_RS00170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_RS00170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_RS00175	COG0084	hydrolase, TatD family'
AN935_RS00180	COG3583	domain protein
AN935_RS00180	COG3584	3D domain protein
AN935_RS00185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AN935_RS00190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN935_RS00200	COG4466	Protein conserved in bacteria
AN935_RS00210	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AN935_RS00215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN935_RS00220	COG0251	oxidation-reduction process
AN935_RS00225	COG2088	sporulation resulting in formation of a cellular spore
AN935_RS00235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AN935_RS00240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN935_RS00245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AN935_RS00250	COG0193	aminoacyl-tRNA hydrolase activity
AN935_RS00260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN935_RS00265	COG2002	toxin-antitoxin pair type II binding
AN935_RS00270	COG2244	polysaccharide biosynthetic process
AN935_RS00275	COG3956	TIGRFAM MazG family protein
AN935_RS00280	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN935_RS00295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AN935_RS00300	COG1098	S1 RNA binding domain
AN935_RS00315	COG2208	phosphoserine phosphatase activity
AN935_RS00320	COG2304	oxidoreductase activity
AN935_RS00325	COG0515	serine threonine protein kinase
AN935_RS00330	COG0037	tRNA processing
AN935_RS00335	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AN935_RS00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN935_RS00345	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AN935_RS00350	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AN935_RS00355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN935_RS00360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN935_RS00365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN935_RS00370	COG0512	Glutamine amidotransferase of anthranilate synthase
AN935_RS00375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_RS00380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN935_RS00385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AN935_RS00390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN935_RS00395	COG1396	sequence-specific DNA binding
AN935_RS00400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN935_RS00405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AN935_RS00415	COG4463	regulation of RNA biosynthetic process
AN935_RS00420	COG3880	PFAM UvrB UvrC protein
AN935_RS00425	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AN935_RS00430	COG0542	response to heat
AN935_RS00435	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AN935_RS00440	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AN935_RS00445	COG4956	integral membrane protein (PIN domain superfamily)
AN935_RS00450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AN935_RS00455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AN935_RS00460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN935_RS00470	COG1045	serine acetyltransferase
AN935_RS00475	COG0215	cysteine-tRNA ligase activity
AN935_RS00480	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AN935_RS00485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN935_RS00490	COG3688	RNA-binding protein containing a PIN domain
AN935_RS00495	COG1595	DNA-templated transcription, initiation
AN935_RS00505	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN935_RS00510	COG0250	Participates in transcription elongation, termination and antitermination
AN935_RS00520	COG0081	regulation of translation
AN935_RS00525	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AN935_RS00535	COG2813	Specifically methylates the guanine in position
AN935_RS00540	COG0085	RNA polymerase activity
AN935_RS00545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AN935_RS00550	COG1358	cellular component organization or biogenesis
AN935_RS00555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AN935_RS00560	COG0049	tRNA binding
AN935_RS00565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AN935_RS00570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AN935_RS00575	COG0596	Alpha beta hydrolase
AN935_RS00585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AN935_RS00600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AN935_RS00620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AN935_RS00630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AN935_RS00635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AN935_RS00645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AN935_RS00655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AN935_RS00660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AN935_RS00665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AN935_RS00680	COG0200	Binds to the 23S rRNA
AN935_RS00685	COG0201	protein transport
AN935_RS00690	COG0563	adenylate kinase activity
AN935_RS00695	COG0024	Methionine aminopeptidase
AN935_RS00710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AN935_RS00715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AN935_RS00720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AN935_RS00725	COG0202	RNA polymerase activity
AN935_RS00730	COG0203	ribosomal protein L17
AN935_RS00735	COG1122	ATPase activity
AN935_RS00740	COG1122	ATPase activity
AN935_RS00745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AN935_RS00750	COG0101	tRNA pseudouridine synthase activity
AN935_RS00755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AN935_RS00760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AN935_RS00765	COG2226	methyltransferase
AN935_RS00775	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_RS00780	COG0489	protein tyrosine kinase activity
AN935_RS00790	COG2194	sulfuric ester hydrolase activity
AN935_RS00795	COG0726	polysaccharide deacetylase
AN935_RS00800	COG0738	Major facilitator superfamily
AN935_RS00805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN935_RS00815	COG1063	alcohol dehydrogenase
AN935_RS00820	COG0659	secondary active sulfate transmembrane transporter activity
AN935_RS00825	COG0385	Bile acid
AN935_RS00830	COG2819	hydrolase of the alpha beta superfamily
AN935_RS00835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS00840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS00845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_RS00850	COG2207	Transcriptional regulator
AN935_RS00850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_RS00855	COG3876	Protein conserved in bacteria
AN935_RS00860	COG1472	Belongs to the glycosyl hydrolase 3 family
AN935_RS00865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN935_RS00870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS00870	COG1263	PTS System
AN935_RS00875	COG1737	Transcriptional regulator
AN935_RS00880	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AN935_RS00885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS00890	COG1683	Conserved Protein
AN935_RS00905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS00935	COG1595	DNA-templated transcription, initiation
AN935_RS00940	COG5662	AntiSigma factor
AN935_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AN935_RS00950	COG4856	YbbR-like protein
AN935_RS00955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN935_RS00965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN935_RS00970	COG3002	Belongs to the UPF0753 family
AN935_RS00975	COG0288	reversible hydration of carbon dioxide
AN935_RS00985	COG5609	conserved protein (DUF2294)
AN935_RS00990	COG0640	Transcriptional regulator
AN935_RS00995	COG2814	Major facilitator Superfamily
AN935_RS01000	COG1413	lyase activity
AN935_RS01010	COG0789	Transcriptional regulator
AN935_RS01015	COG0596	Alpha beta hydrolase
AN935_RS01020	COG0745	RESPONSE REGULATOR receiver
AN935_RS01025	COG0642	Histidine kinase
AN935_RS01035	COG0515	serine threonine protein kinase
AN935_RS01050	COG1113	amino acid transport
AN935_RS01065	COG2602	Beta-lactamase
AN935_RS01070	COG2124	cytochrome p450
AN935_RS01080	COG0531	amino acid
AN935_RS01085	COG1283	sodium-dependent phosphate transmembrane transporter activity
AN935_RS01090	COG0584	glycerophosphoryl diester phosphodiesterase
AN935_RS01095	COG2271	Major facilitator Superfamily
AN935_RS01105	COG1846	Transcriptional regulator
AN935_RS01105	COG0456	acetyltransferase
AN935_RS01110	COG2271	Major facilitator Superfamily
AN935_RS01125	COG0697	spore germination
AN935_RS01130	COG2207	Transcriptional regulator
AN935_RS01130	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS01135	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AN935_RS01140	COG3591	Belongs to the peptidase S1B family
AN935_RS01150	COG0596	Alpha beta hydrolase
AN935_RS01155	COG1183	phosphatidylcholine synthase activity
AN935_RS01160	COG0586	Pfam SNARE associated Golgi protein
AN935_RS01165	COG0688	phosphatidylethanolamine metabolic process
AN935_RS01175	COG2312	Erythromycin esterase
AN935_RS01180	COG2207	Transcriptional regulator
AN935_RS01185	COG1054	Belongs to the UPF0176 family
AN935_RS01190	COG1301	dicarboxylic acid transport
AN935_RS01195	COG1263	PTS System
AN935_RS01195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS01195	COG2190	(PTS) system
AN935_RS01200	COG0363	glucosamine-6-phosphate deaminase activity
AN935_RS01205	COG2188	Transcriptional regulator
AN935_RS01215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_RS01220	COG0833	amino acid
AN935_RS01225	COG2040	homocysteine
AN935_RS01235	COG1115	amino acid carrier protein
AN935_RS01240	COG2066	Belongs to the glutaminase family
AN935_RS01245	COG4191	Histidine kinase
AN935_RS01250	COG0784	Response regulator, receiver
AN935_RS01255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN935_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS01265	COG2271	Major facilitator Superfamily
AN935_RS01270	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_RS01275	COG2186	Transcriptional regulator
AN935_RS01280	COG2721	sulfolactate sulfo-lyase activity
AN935_RS01285	COG3173	Aminoglycoside phosphotransferase
AN935_RS01295	COG0697	spore germination
AN935_RS01300	COG0745	RESPONSE REGULATOR receiver
AN935_RS01305	COG2205	protein histidine kinase activity
AN935_RS01310	COG1131	(ABC) transporter
AN935_RS01330	COG3773	Cell wall hydrolase
AN935_RS01335	COG2304	oxidoreductase activity
AN935_RS01345	COG3540	Alkaline phosphatase
AN935_RS01350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN935_RS01355	COG0805	protein transport
AN935_RS01360	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AN935_RS01365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN935_RS01370	COG0477	Major facilitator Superfamily
AN935_RS01375	COG1309	transcriptional regulator
AN935_RS01380	COG0252	asparaginase activity
AN935_RS01385	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AN935_RS01390	COG1714	RDD family
AN935_RS01395	COG1405	negative regulation of cell septum assembly
AN935_RS01395	COG3012	SEC-C Motif Domain Protein
AN935_RS01400	COG3290	protein histidine kinase activity
AN935_RS01405	COG3279	Response regulator of the LytR AlgR family
AN935_RS01410	COG4555	ABC transporter
AN935_RS01415	COG1668	transmembrane transport
AN935_RS01420	COG0667	Aldo Keto reductase
AN935_RS01430	COG1595	DNA-templated transcription, initiation
AN935_RS01435	COG1595	DNA-templated transcription, initiation
AN935_RS01445	COG0457	Tetratricopeptide repeat
AN935_RS01450	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS01455	COG0366	Alpha amylase catalytic
AN935_RS01460	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN935_RS01465	COG1121	(ABC) transporter
AN935_RS01470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN935_RS01475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS01480	COG2310	stress, protein
AN935_RS01485	COG2310	stress, protein
AN935_RS01490	COG2310	stress, protein
AN935_RS01495	COG0861	Integral membrane protein TerC family
AN935_RS01505	COG3853	Toxic anion resistance protein (TelA)
AN935_RS01510	COG0477	Major facilitator Superfamily
AN935_RS01515	COG2814	Major facilitator Superfamily
AN935_RS01520	COG0640	Transcriptional regulator
AN935_RS01525	COG0517	IMP dehydrogenase activity
AN935_RS01525	COG4175	Glycine betaine
AN935_RS01530	COG4176	ABC-type proline glycine betaine transport system permease component
AN935_RS01535	COG2113	Glycine betaine
AN935_RS01540	COG1473	amidohydrolase
AN935_RS01545	COG1288	antiporter activity
AN935_RS01560	COG0366	Alpha amylase catalytic
AN935_RS01565	COG0039	L-malate dehydrogenase activity
AN935_RS01570	COG1620	l-lactate permease
AN935_RS01575	COG2814	Major facilitator Superfamily
AN935_RS01580	COG1846	Transcriptional regulator
AN935_RS01585	COG1280	lysine exporter protein (LysE YggA)
AN935_RS01590	COG3403	YqcI/YcgG family
AN935_RS01595	COG1113	amino acid transport
AN935_RS01600	COG3665	Urea carboxylase-associated protein
AN935_RS01605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN935_RS01610	COG1660	Displays ATPase and GTPase activities
AN935_RS01615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AN935_RS01620	COG2226	methyltransferase
AN935_RS01625	COG0583	DNA-binding transcription factor activity
AN935_RS01630	COG3458	cephalosporin-C deacetylase activity
AN935_RS01635	COG3541	Predicted nucleotidyltransferase
AN935_RS01640	COG0506	proline dehydrogenase activity
AN935_RS01645	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS01650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_RS01655	COG2508	Transcriptional regulator
AN935_RS01660	COG3689	TIGRFAM TIGR03943 family protein
AN935_RS01665	COG0701	Predicted permease
AN935_RS01675	COG0492	ferredoxin-NADP+ reductase activity
AN935_RS01680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN935_RS01680	COG1587	Uroporphyrinogen-III synthase
AN935_RS01685	COG2146	nitrite reductase [NAD(P)H] activity
AN935_RS01690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN935_RS01695	COG0243	molybdopterin cofactor binding
AN935_RS01700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN935_RS01705	COG2223	nitrite transmembrane transporter activity
AN935_RS01710	COG1469	GTP cyclohydrolase I activity
AN935_RS01715	COG1376	ErfK ybiS ycfS ynhG family protein
AN935_RS01725	COG0523	cobalamin synthesis protein
AN935_RS01730	COG0765	amino acid transport
AN935_RS01735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS01740	COG1714	RDD family
AN935_RS01750	COG1846	Transcriptional regulator
AN935_RS01760	COG3842	ATPase activity
AN935_RS01765	COG2723	6-phospho-beta-galactosidase activity
AN935_RS01775	COG3209	COG3209 Rhs family protein
AN935_RS01780	COG0840	transmembrane signaling receptor activity
AN935_RS01780	COG3290	protein histidine kinase activity
AN935_RS01785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AN935_RS01790	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AN935_RS01795	COG1733	regulation of RNA biosynthetic process
AN935_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS01815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN935_RS01820	COG2814	Major facilitator Superfamily
AN935_RS01830	COG0697	spore germination
AN935_RS01835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS01845	COG2364	Membrane
AN935_RS01850	COG1126	abc transporter atp-binding protein
AN935_RS01855	COG0765	amino acid transport
AN935_RS01860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS01865	COG0583	DNA-binding transcription factor activity
AN935_RS01870	COG0163	prenyltransferase activity
AN935_RS01875	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AN935_RS01890	COG0596	Alpha beta hydrolase
AN935_RS01895	COG3104	oligopeptide transport
AN935_RS01900	COG5434	Belongs to the glycosyl hydrolase 28 family
AN935_RS01910	COG0697	spore germination
AN935_RS01920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN935_RS01925	COG1136	(ABC) transporter
AN935_RS01930	COG0577	efflux transmembrane transporter activity
AN935_RS01935	COG0745	RESPONSE REGULATOR receiver
AN935_RS01940	COG3850	Histidine kinase
AN935_RS01940	COG5002	protein histidine kinase activity
AN935_RS01945	COG0457	Tetratricopeptide repeat
AN935_RS01960	COG0527	aspartate kinase activity
AN935_RS01965	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS01970	COG4605	iron ion homeostasis
AN935_RS01975	COG4604	ABC transporter, ATP-binding protein
AN935_RS01980	COG4607	ABC-type enterochelin transport system periplasmic component
AN935_RS01985	COG2814	Major facilitator Superfamily
AN935_RS01990	COG1309	transcriptional regulator
AN935_RS01995	COG0778	Nitroreductase
AN935_RS02000	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN935_RS02005	COG0640	Transcriptional regulator
AN935_RS02010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS02015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN935_RS02020	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS02025	COG4975	Glucose uptake
AN935_RS02030	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS02035	COG4549	nuclear export factor GLE1
AN935_RS02040	COG2372	response to copper ion
AN935_RS02040	COG1276	copper resistance
AN935_RS02045	COG1349	DNA-binding transcription factor activity
AN935_RS02055	COG2213	PTS system mannitol-specific
AN935_RS02060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS02065	COG0246	Mannitol dehydrogenase
AN935_RS02070	COG0473	3-isopropylmalate dehydrogenase activity
AN935_RS02075	COG0412	Dienelactone hydrolase
AN935_RS02080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN935_RS02090	COG0561	phosphatase activity
AN935_RS02095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AN935_RS02100	COG1914	H( )-stimulated, divalent metal cation uptake system
AN935_RS02105	COG4336	lyase activity
AN935_RS02110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AN935_RS02115	COG1984	allophanate hydrolase subunit 2
AN935_RS02120	COG1414	Transcriptional regulator
AN935_RS02125	COG2755	lipolytic protein G-D-S-L family
AN935_RS02135	COG2329	Antibiotic biosynthesis monooxygenase
AN935_RS02140	COG0768	penicillin binding
AN935_RS02145	COG4989	oxidoreductase activity
AN935_RS02150	COG3711	transcriptional antiterminator
AN935_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_RS02160	COG2226	methyltransferase
AN935_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS02170	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS02180	COG3871	stress protein (general stress protein 26)
AN935_RS02190	COG2814	Major facilitator Superfamily
AN935_RS02195	COG1522	sequence-specific DNA binding
AN935_RS02200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN935_RS02200	COG0551	DNA topoisomerase type I activity
AN935_RS02205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AN935_RS02210	COG3706	GGDEF domain
AN935_RS02215	COG5298	Protein conserved in bacteria
AN935_RS02220	COG1215	transferase activity, transferring glycosyl groups
AN935_RS02230	COG0531	amino acid
AN935_RS02240	COG0028	Belongs to the TPP enzyme family
AN935_RS02255	COG1914	H( )-stimulated, divalent metal cation uptake system
AN935_RS02260	COG2261	transglycosylase associated protein
AN935_RS02265	COG4876	unkown
AN935_RS02270	COG2217	Heavy metal translocating P-type atpase
AN935_RS02275	COG3729	General stress protein
AN935_RS02280	COG0662	Cupin 2, conserved barrel domain protein
AN935_RS02285	COG2329	Antibiotic biosynthesis monooxygenase
AN935_RS02290	COG3546	catalase activity
AN935_RS02295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AN935_RS02300	COG3290	protein histidine kinase activity
AN935_RS02305	COG4565	transcriptional regulatory protein
AN935_RS02310	COG1301	dicarboxylic acid transport
AN935_RS02315	COG0628	permease
AN935_RS02320	COG1301	dicarboxylic acid transport
AN935_RS02325	COG1131	(ABC) transporter
AN935_RS02330	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AN935_RS02340	COG1960	acyl-CoA dehydrogenase activity
AN935_RS02355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN935_RS02360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS02365	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN935_RS02370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN935_RS02380	COG0513	Belongs to the DEAD box helicase family
AN935_RS02385	COG3402	PFAM membrane-flanked domain
AN935_RS02390	COG3428	Bacterial PH domain
AN935_RS02395	COG0705	Rhomboid family
AN935_RS02400	COG0736	holo-[acyl-carrier-protein] synthase activity
AN935_RS02405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AN935_RS02410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN935_RS02415	COG0864	Transcriptional regulator
AN935_RS02420	COG2337	Toxic component of a toxin-antitoxin (TA) module
AN935_RS02425	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS02430	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS02435	COG2172	sigma factor antagonist activity
AN935_RS02440	COG2208	phosphoserine phosphatase activity
AN935_RS02445	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS02450	COG2172	sigma factor antagonist activity
AN935_RS02455	COG1191	sigma factor activity
AN935_RS02460	COG2208	phosphoserine phosphatase activity
AN935_RS02465	COG2183	response to ionizing radiation
AN935_RS02475	COG3091	SprT-like family
AN935_RS02520	COG1846	Transcriptional regulator
AN935_RS02525	COG2070	2-Nitropropane dioxygenase
AN935_RS02530	COG0431	NADPH-dependent FMN reductase
AN935_RS02535	COG4978	Transcriptional regulator
AN935_RS02535	COG0789	Transcriptional regulator
AN935_RS02540	COG0702	epimerase
AN935_RS02545	COG0697	spore germination
AN935_RS02555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS02560	COG0697	spore germination
AN935_RS02565	COG1476	TRANSCRIPTIONal
AN935_RS02585	COG2807	transmembrane transport
AN935_RS02595	COG1278	Cold shock
AN935_RS02600	COG1329	Transcriptional regulator
AN935_RS02605	COG2207	Transcriptional regulator
AN935_RS02605	COG3708	Transcriptional regulator
AN935_RS02615	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AN935_RS02620	COG2814	Major facilitator Superfamily
AN935_RS02630	COG1309	transcriptional regulator
AN935_RS02635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS02640	COG1316	TRANSCRIPTIONal
AN935_RS02655	COG5002	protein histidine kinase activity
AN935_RS02660	COG0745	RESPONSE REGULATOR receiver
AN935_RS02665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS02680	COG1114	Component of the transport system for branched-chain amino acids
AN935_RS02685	COG0583	DNA-binding transcription factor activity
AN935_RS02690	COG0114	fumarate hydratase activity
AN935_RS02695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AN935_RS02700	COG1522	sequence-specific DNA binding
AN935_RS02705	COG0697	spore germination
AN935_RS02710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS02715	COG2030	dehydratase
AN935_RS02720	COG3545	Serine hydrolase
AN935_RS02725	COG1733	regulation of RNA biosynthetic process
AN935_RS02730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS02740	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN935_RS02745	COG0640	Transcriptional regulator
AN935_RS02750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AN935_RS02755	COG0789	Transcriptional regulator
AN935_RS02760	COG0697	spore germination
AN935_RS02765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS02770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN935_RS02775	COG0640	Transcriptional regulator
AN935_RS02780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN935_RS02790	COG4585	Histidine kinase
AN935_RS02795	COG2197	response regulator
AN935_RS02800	COG2409	Drug exporters of the RND superfamily
AN935_RS02805	COG1811	Na channel or pump
AN935_RS02810	COG4978	Transcriptional regulator
AN935_RS02810	COG0789	Transcriptional regulator
AN935_RS02815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN935_RS02820	COG0778	Nitroreductase
AN935_RS02825	COG0346	lactoylglutathione lyase activity
AN935_RS02830	COG2259	Doxx family
AN935_RS02835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS02850	COG1309	transcriptional regulator
AN935_RS02860	COG0456	acetyltransferase
AN935_RS02865	COG0673	inositol 2-dehydrogenase activity
AN935_RS02870	COG1609	Transcriptional regulator
AN935_RS02875	COG2814	Major facilitator Superfamily
AN935_RS02880	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS02885	COG0488	(ABC) transporter
AN935_RS02890	COG1113	amino acid transport
AN935_RS02895	COG2318	DinB family
AN935_RS02900	COG1846	Transcriptional regulator
AN935_RS02905	COG2409	Drug exporters of the RND superfamily
AN935_RS02905	COG1033	growth of symbiont in host cell
AN935_RS02915	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS02920	COG0778	Nitroreductase
AN935_RS02925	COG1846	Transcriptional regulator
AN935_RS02930	COG1396	sequence-specific DNA binding
AN935_RS02945	COG2814	Major facilitator Superfamily
AN935_RS02950	COG0730	response to heat
AN935_RS02955	COG1802	Transcriptional regulator
AN935_RS02960	COG3858	chitin binding
AN935_RS02960	COG1388	LysM domain
AN935_RS02965	COG1819	glycosyl
AN935_RS02975	COG1785	Belongs to the alkaline phosphatase family
AN935_RS02980	COG5646	InterPro IPR014922
AN935_RS02990	COG0454	-acetyltransferase
AN935_RS02995	COG1078	dGTPase activity
AN935_RS03000	COG1388	LysM domain
AN935_RS03005	COG2814	Major facilitator Superfamily
AN935_RS03010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_RS03015	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN935_RS03025	COG2723	6-phospho-beta-galactosidase activity
AN935_RS03030	COG2188	Transcriptional regulator
AN935_RS03035	COG1940	carbohydrate kinase activity
AN935_RS03040	COG1482	cell wall glycoprotein biosynthetic process
AN935_RS03045	COG4124	Belongs to the glycosyl hydrolase 26 family
AN935_RS03075	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AN935_RS03080	COG0802	atpase or kinase
AN935_RS03085	COG1214	PFAM Peptidase M22, glycoprotease
AN935_RS03090	COG0456	acetyltransferase
AN935_RS03095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AN935_RS03100	COG0488	(ABC) transporter
AN935_RS03105	COG0315	cyclic pyranopterin monophosphate synthase activity
AN935_RS03110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AN935_RS03115	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN935_RS03120	COG0805	protein transport
AN935_RS03130	COG1266	CAAX protease self-immunity
AN935_RS03140	COG0459	protein refolding
AN935_RS03150	COG0457	Tetratricopeptide repeat
AN935_RS03155	COG1063	alcohol dehydrogenase
AN935_RS03160	COG2211	Major facilitator Superfamily
AN935_RS03165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_RS03175	COG2814	Major facilitator Superfamily
AN935_RS03180	COG1063	alcohol dehydrogenase
AN935_RS03185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN935_RS03190	COG0823	Involved in the tonB-independent uptake of proteins
AN935_RS03205	COG2267	carboxylic ester hydrolase activity
AN935_RS03215	COG2132	Multicopper oxidase
AN935_RS03220	COG1113	amino acid transport
AN935_RS03230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AN935_RS03235	COG0714	Associated with various cellular activities
AN935_RS03240	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AN935_RS03245	COG1305	Transglutaminase-like
AN935_RS03250	COG0519	Catalyzes the synthesis of GMP from XMP
AN935_RS03250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN935_RS03265	COG2252	PERMEase
AN935_RS03270	COG3064	Membrane
AN935_RS03280	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AN935_RS03290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AN935_RS03295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AN935_RS03300	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN935_RS03305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AN935_RS03310	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN935_RS03315	COG0047	phosphoribosylformylglycinamidine synthase activity
AN935_RS03320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN935_RS03325	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AN935_RS03330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AN935_RS03335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN935_RS03340	COG0138	bifunctional purine biosynthesis protein purh
AN935_RS03345	COG0151	Belongs to the GarS family
AN935_RS03350	COG1522	sequence-specific DNA binding
AN935_RS03355	COG0531	amino acid
AN935_RS03365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AN935_RS03370	COG1470	cell adhesion involved in biofilm formation
AN935_RS03375	COG4496	protein, YerC YecD
AN935_RS03380	COG0069	glutamate synthase activity
AN935_RS03385	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AN935_RS03390	COG0210	DNA helicase
AN935_RS03395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AN935_RS03400	COG4851	CamS sex pheromone cAM373 precursor
AN935_RS03405	COG2814	Major facilitator Superfamily
AN935_RS03425	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN935_RS03430	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN935_RS03445	COG1960	acyl-CoA dehydrogenase activity
AN935_RS03475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN935_RS03480	COG1785	Belongs to the alkaline phosphatase family
AN935_RS03490	COG1285	pathogenesis
AN935_RS03495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_RS03500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN935_RS03505	COG0154	amidase activity
AN935_RS03510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN935_RS03515	COG1309	transcriptional regulator
AN935_RS03520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN935_RS03525	COG1597	lipid kinase activity
AN935_RS03530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN935_RS03580	COG3391	amine dehydrogenase activity
AN935_RS03590	COG0457	Tetratricopeptide repeat
AN935_RS03600	COG0217	transcriptional regulatory protein
AN935_RS03610	COG1309	transcriptional regulator
AN935_RS03615	COG3631	Ketosteroid isomerase-related protein
AN935_RS03620	COG0702	epimerase
AN935_RS03635	COG3546	catalase activity
AN935_RS03640	COG0454	-acetyltransferase
AN935_RS03650	COG5578	integral membrane protein
AN935_RS03655	COG2972	Histidine kinase
AN935_RS03660	COG2207	Transcriptional regulator
AN935_RS03660	COG4753	response regulator
AN935_RS03665	COG1653	transport
AN935_RS03670	COG1175	transmembrane transport
AN935_RS03675	COG0395	ABC-type sugar transport system, permease component
AN935_RS03680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AN935_RS03685	COG2207	Transcriptional regulator
AN935_RS03690	COG2755	lipolytic protein G-D-S-L family
AN935_RS03700	COG5578	integral membrane protein
AN935_RS03705	COG3401	FG-GAP repeat protein
AN935_RS03710	COG3401	FG-GAP repeat protein
AN935_RS03715	COG2755	lipolytic protein G-D-S-L family
AN935_RS03720	COG1874	Beta-galactosidase
AN935_RS03730	COG1653	transport
AN935_RS03735	COG4209	transmembrane transport
AN935_RS03740	COG0395	ABC-type sugar transport system, permease component
AN935_RS03745	COG1486	melibiose metabolic process
AN935_RS03750	COG2323	membrane
AN935_RS03755	COG2329	Antibiotic biosynthesis monooxygenase
AN935_RS03760	COG0346	lactoylglutathione lyase activity
AN935_RS03770	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS03775	COG5583	Uncharacterized small protein (DUF2292)
AN935_RS03780	COG0670	Belongs to the BI1 family
AN935_RS03785	COG0697	spore germination
AN935_RS03790	COG1846	Transcriptional regulator
AN935_RS03795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN935_RS03810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN935_RS03810	COG2124	cytochrome p450
AN935_RS03815	COG1368	sulfuric ester hydrolase activity
AN935_RS03820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AN935_RS03825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_RS03830	COG1442	glycosyl transferase family 8
AN935_RS03835	COG1216	Glycosyl transferase, family 2
AN935_RS03840	COG1442	glycosyl transferase family 8
AN935_RS03845	COG2223	nitrite transmembrane transporter activity
AN935_RS03850	COG1011	Hydrolase
AN935_RS03855	COG0531	amino acid
AN935_RS03860	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS03865	COG0840	transmembrane signaling receptor activity
AN935_RS03870	COG0488	(ABC) transporter
AN935_RS03880	COG0789	Transcriptional regulator
AN935_RS03885	COG2814	Major facilitator Superfamily
AN935_RS03890	COG0488	(ABC) transporter
AN935_RS03895	COG0513	Belongs to the DEAD box helicase family
AN935_RS03900	COG0456	acetyltransferase
AN935_RS03905	COG2130	NADP-dependent
AN935_RS03910	COG1120	ATPase activity
AN935_RS03915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS03920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS03925	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AN935_RS03940	COG3866	Pectate lyase
AN935_RS03945	COG0471	metal ion transport
AN935_RS03950	COG3290	protein histidine kinase activity
AN935_RS03955	COG4565	transcriptional regulatory protein
AN935_RS03960	COG3181	Tripartite tricarboxylate transporter family receptor
AN935_RS03970	COG2851	Citrate transporter
AN935_RS03975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS03980	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AN935_RS03985	COG1254	Belongs to the acylphosphatase family
AN935_RS03990	COG2258	MOSC domain
AN935_RS04010	COG0024	Methionine aminopeptidase
AN935_RS04015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS04015	COG1263	PTS System
AN935_RS04020	COG1368	sulfuric ester hydrolase activity
AN935_RS04030	COG1115	amino acid carrier protein
AN935_RS04040	COG1263	PTS System
AN935_RS04040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS04045	COG0366	Alpha amylase catalytic
AN935_RS04050	COG2188	Transcriptional regulator
AN935_RS04055	COG0778	Nitroreductase
AN935_RS04060	COG0737	Belongs to the 5'-nucleotidase family
AN935_RS04065	COG0693	protein deglycase activity
AN935_RS04070	COG2814	Major facilitator Superfamily
AN935_RS04075	COG4840	Belongs to the UPF0435 family
AN935_RS04080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN935_RS04085	COG4980	gas vesicle protein
AN935_RS04090	COG1295	ribonuclease BN
AN935_RS04100	COG0477	Major facilitator Superfamily
AN935_RS04110	COG0387	Pfam Sodium calcium exchanger
AN935_RS04120	COG0668	transmembrane transport
AN935_RS04125	COG0535	radical SAM domain protein
AN935_RS04135	COG0726	polysaccharide deacetylase
AN935_RS04140	COG2084	Dehydrogenase
AN935_RS04145	COG0598	Magnesium transport protein CorA
AN935_RS04150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AN935_RS04155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AN935_RS04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN935_RS04170	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AN935_RS04180	COG4637	Psort location Cytoplasmic, score
AN935_RS04185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN935_RS04190	COG0022	dehydrogenase e1 component
AN935_RS04195	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_RS04200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN935_RS04205	COG3284	Transcriptional regulator
AN935_RS04215	COG1742	UPF0060 membrane protein
AN935_RS04235	COG4842	Belongs to the WXG100 family
AN935_RS04240	COG1486	melibiose metabolic process
AN935_RS04245	COG1737	Transcriptional regulator
AN935_RS04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS04250	COG1263	PTS System
AN935_RS04255	COG1132	(ABC) transporter
AN935_RS04260	COG1132	(ABC) transporter
AN935_RS04265	COG2259	Doxx family
AN935_RS04270	COG2514	catechol 2,3-dioxygenase activity
AN935_RS04275	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS04275	COG4977	sequence-specific DNA binding
AN935_RS04280	COG2814	Major facilitator Superfamily
AN935_RS04285	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS04290	COG0673	inositol 2-dehydrogenase activity
AN935_RS04295	COG4585	Histidine kinase
AN935_RS04300	COG2197	response regulator
AN935_RS04305	COG1131	(ABC) transporter
AN935_RS04310	COG1511	domain protein
AN935_RS04310	COG0842	Transport permease protein
AN935_RS04315	COG0842	Transport permease protein
AN935_RS04325	COG1695	Transcriptional regulator
AN935_RS04330	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AN935_RS04350	COG1131	(ABC) transporter
AN935_RS04355	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AN935_RS04360	COG2318	DinB family
AN935_RS04365	COG2814	Major facilitator Superfamily
AN935_RS04370	COG1846	Transcriptional regulator
AN935_RS04375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AN935_RS04375	COG0392	lysyltransferase activity
AN935_RS04380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_RS04385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS04390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS04395	COG0384	phenazine biosynthesis protein PhzF
AN935_RS04400	COG0778	Nitroreductase
AN935_RS04415	COG1090	epimerase
AN935_RS04420	COG2137	regulation of response to DNA damage stimulus
AN935_RS04435	COG2814	Major facilitator Superfamily
AN935_RS04450	COG3103	Sh3 type 3 domain protein
AN935_RS04455	COG5658	integral membrane protein
AN935_RS04460	COG0596	Alpha beta hydrolase
AN935_RS04465	COG0463	Glycosyl transferase, family 2
AN935_RS04470	COG4485	Bacterial membrane protein, YfhO
AN935_RS04475	COG1988	membrane-bound metal-dependent
AN935_RS04480	COG1194	a g-specific adenine glycosylase
AN935_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS04505	COG3557	Belongs to the UPF0374 family
AN935_RS04510	COG1132	(ABC) transporter
AN935_RS04515	COG4129	membrane
AN935_RS04520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN935_RS04525	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN935_RS04530	COG0735	belongs to the Fur family
AN935_RS04570	COG4326	sporulation control protein
AN935_RS04580	COG5577	PFAM Coat F domain
AN935_RS04585	COG3340	Belongs to the peptidase S51 family
AN935_RS04590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AN935_RS04600	COG0753	catalase activity
AN935_RS04605	COG1116	anion transmembrane transporter activity
AN935_RS04610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN935_RS04615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN935_RS04620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS04630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AN935_RS04640	COG1476	TRANSCRIPTIONal
AN935_RS04650	COG3382	B3 4 domain protein
AN935_RS04655	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN935_RS04665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AN935_RS04670	COG0789	Transcriptional regulator
AN935_RS04675	COG1664	Polymer-forming cytoskeletal
AN935_RS04680	COG1664	Polymer-forming cytoskeletal
AN935_RS04685	COG2766	serine protein kinase
AN935_RS04690	COG2718	Belongs to the UPF0229 family
AN935_RS04700	COG1846	Transcriptional regulator
AN935_RS04705	COG1566	PFAM secretion protein HlyD family protein
AN935_RS04710	COG2814	Major facilitator Superfamily
AN935_RS04715	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN935_RS04730	COG1725	Transcriptional regulator
AN935_RS04735	COG1131	(ABC) transporter
AN935_RS04740	COG1131	(ABC) transporter
AN935_RS04745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AN935_RS04750	COG1278	Cold shock
AN935_RS04755	COG1464	Belongs to the NlpA lipoprotein family
AN935_RS04760	COG3706	GGDEF domain
AN935_RS04765	COG1823	symporter activity
AN935_RS04770	COG0456	acetyltransferase
AN935_RS04775	COG1396	sequence-specific DNA binding
AN935_RS04795	COG5577	PFAM Coat F domain
AN935_RS04800	COG4085	toxin activity
AN935_RS04800	COG0737	Belongs to the 5'-nucleotidase family
AN935_RS04800	COG1525	nuclease
AN935_RS04805	COG3764	Sortase (surface protein transpeptidase)
AN935_RS04810	COG0564	pseudouridine synthase activity
AN935_RS04820	COG0517	IMP dehydrogenase activity
AN935_RS04825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN935_RS04830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN935_RS04830	COG3153	acetyltransferase
AN935_RS04840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AN935_RS04845	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AN935_RS04850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AN935_RS04855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN935_RS04860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AN935_RS04865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN935_RS04870	COG4585	Histidine kinase
AN935_RS04870	COG2203	Gaf domain
AN935_RS04875	COG2197	response regulator
AN935_RS04880	COG0431	NADPH-dependent FMN reductase
AN935_RS04895	COG0791	NLP P60 protein
AN935_RS04895	COG1388	LysM domain
AN935_RS04900	COG1959	2 iron, 2 sulfur cluster binding
AN935_RS04905	COG0668	transmembrane transport
AN935_RS04910	COG2719	SpoVR family
AN935_RS04915	COG1785	Belongs to the alkaline phosphatase family
AN935_RS04920	COG0791	NLP P60 protein
AN935_RS04920	COG1388	LysM domain
AN935_RS04925	COG0583	DNA-binding transcription factor activity
AN935_RS04930	COG0372	Belongs to the citrate synthase family
AN935_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS04940	COG0531	amino acid
AN935_RS04945	COG0733	neurotransmitter:sodium symporter activity
AN935_RS04950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS04955	COG0456	acetyltransferase
AN935_RS04970	COG1595	DNA-templated transcription, initiation
AN935_RS04975	COG0667	Aldo Keto reductase
AN935_RS04980	COG0204	Acyl-transferase
AN935_RS04985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_RS04995	COG1253	flavin adenine dinucleotide binding
AN935_RS05000	COG0789	Transcriptional regulator
AN935_RS05005	COG0436	Aminotransferase
AN935_RS05010	COG1253	flavin adenine dinucleotide binding
AN935_RS05015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN935_RS05020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AN935_RS05025	COG0584	glycerophosphoryl diester phosphodiesterase
AN935_RS05035	COG0668	transmembrane transport
AN935_RS05040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AN935_RS05045	COG0726	polysaccharide deacetylase
AN935_RS05050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_RS05055	COG1757	Na H antiporter
AN935_RS05060	COG0589	response to stress
AN935_RS05070	COG1132	(ABC) transporter
AN935_RS05075	COG1132	(ABC) transporter
AN935_RS05080	COG0702	epimerase
AN935_RS05095	COG0189	ligase activity
AN935_RS05100	COG0189	ligase activity
AN935_RS05105	COG4399	Belongs to the UPF0754 family
AN935_RS05110	COG3679	Belongs to the UPF0342 family
AN935_RS05115	COG4335	DNA alkylation repair
AN935_RS05120	COG0561	phosphatase activity
AN935_RS05125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN935_RS05130	COG0475	glutathione-regulated potassium exporter activity
AN935_RS05135	COG0490	domain, Protein
AN935_RS05145	COG1024	Enoyl-CoA hydratase
AN935_RS05155	COG4152	abc transporter atp-binding protein
AN935_RS05160	COG1668	transmembrane transport
AN935_RS05165	COG0420	3'-5' exonuclease activity
AN935_RS05170	COG4717	serine-type aminopeptidase activity
AN935_RS05175	COG3481	metal-dependent phosphohydrolase, HD sub domain
AN935_RS05185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN935_RS05205	COG1846	Transcriptional regulator
AN935_RS05210	COG4980	gas vesicle protein
AN935_RS05225	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AN935_RS05230	COG0537	adenosine 5'-monophosphoramidase activity
AN935_RS05235	COG1131	(ABC) transporter
AN935_RS05240	COG4473	ABC transporter
AN935_RS05250	COG1473	amidohydrolase
AN935_RS05255	COG3069	C4-dicarboxylate transmembrane transporter activity
AN935_RS05265	COG2329	Antibiotic biosynthesis monooxygenase
AN935_RS05270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_RS05275	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AN935_RS05280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AN935_RS05285	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AN935_RS05290	COG1309	transcriptional regulator
AN935_RS05295	COG1511	domain protein
AN935_RS05300	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN935_RS05305	COG4377	Putative membrane peptidase family (DUF2324)
AN935_RS05315	COG1363	Peptidase, m42
AN935_RS05320	COG4405	Protein conserved in bacteria
AN935_RS05325	COG1301	dicarboxylic acid transport
AN935_RS05335	COG1234	tRNA 3'-trailer cleavage
AN935_RS05340	COG0095	Lipoate-protein ligase
AN935_RS05345	COG0702	epimerase
AN935_RS05350	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_RS05360	COG0501	Belongs to the peptidase M48B family
AN935_RS05365	COG1404	Belongs to the peptidase S8 family
AN935_RS05370	COG0456	acetyltransferase
AN935_RS05375	COG0604	alcohol dehydrogenase
AN935_RS05385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AN935_RS05390	COG0406	alpha-ribazole phosphatase activity
AN935_RS05395	COG0183	Belongs to the thiolase family
AN935_RS05400	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_RS05405	COG1268	BioY protein
AN935_RS05410	COG0840	transmembrane signaling receptor activity
AN935_RS05415	COG0723	plastoquinol--plastocyanin reductase activity
AN935_RS05415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS05430	COG4903	ComK protein
AN935_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS05445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_RS05460	COG0398	Pfam SNARE associated Golgi protein
AN935_RS05465	COG0681	Belongs to the peptidase S26 family
AN935_RS05470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN935_RS05475	COG1846	Transcriptional regulator
AN935_RS05480	COG3180	Ammonia monooxygenase
AN935_RS05485	COG0477	Major facilitator Superfamily
AN935_RS05485	COG2814	Major facilitator Superfamily
AN935_RS05490	COG4533	DNA binding
AN935_RS05500	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AN935_RS05505	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AN935_RS05510	COG1074	ATP-dependent DNA helicase activity
AN935_RS05515	COG0420	3'-5' exonuclease activity
AN935_RS05520	COG0419	ATPase involved in DNA repair
AN935_RS05525	COG1403	HNH endonuclease
AN935_RS05570	COG5337	Spore coat protein CotH
AN935_RS05575	COG0179	Fumarylacetoacetate (FAA) hydrolase
AN935_RS05585	COG1404	Belongs to the peptidase S8 family
AN935_RS05595	COG0367	asparagine synthase
AN935_RS05600	COG1562	ergosterol biosynthetic process
AN935_RS05605	COG0534	Mate efflux family protein
AN935_RS05610	COG2207	Transcriptional regulator
AN935_RS05610	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS05615	COG1609	Transcriptional regulator
AN935_RS05620	COG0673	inositol 2-dehydrogenase activity
AN935_RS05625	COG2318	DinB family
AN935_RS05630	COG1279	arginine transmembrane transporter activity
AN935_RS05635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS05640	COG1357	PFAM Pentapeptide repeats (8 copies)
AN935_RS05645	COG2267	carboxylic ester hydrolase activity
AN935_RS05650	COG0529	Catalyzes the synthesis of activated sulfate
AN935_RS05655	COG2046	Belongs to the sulfate adenylyltransferase family
AN935_RS05660	COG0175	sulfate reduction
AN935_RS05665	COG2045	Belongs to the ComB family
AN935_RS05670	COG1809	phosphosulfolactate synthase activity
AN935_RS05675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS05680	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_RS05685	COG2814	Major facilitator Superfamily
AN935_RS05690	COG0454	-acetyltransferase
AN935_RS05695	COG2153	protein acetylation
AN935_RS05700	COG0646	methionine synthase
AN935_RS05700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN935_RS05705	COG1666	GTP binding
AN935_RS05710	COG2996	Protein conserved in bacteria
AN935_RS05730	COG1695	Transcriptional regulator
AN935_RS05745	COG3227	Zinc metalloprotease (Elastase)
AN935_RS05750	COG1307	EDD domain protein, DegV family
AN935_RS05755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS05775	COG0561	phosphatase activity
AN935_RS05780	COG1073	alpha beta
AN935_RS05785	COG2151	metal-sulfur cluster biosynthetic enzyme
AN935_RS05795	COG0277	FAD linked oxidase domain protein
AN935_RS05800	COG2271	Major facilitator Superfamily
AN935_RS05805	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AN935_RS05810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AN935_RS05820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN935_RS05825	COG0505	Belongs to the CarA family
AN935_RS05830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AN935_RS05835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AN935_RS05850	COG2267	carboxylic ester hydrolase activity
AN935_RS05860	COG1744	ABC transporter substrate-binding protein PnrA-like
AN935_RS05875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN935_RS05880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN935_RS05885	COG5504	Zn-dependent protease
AN935_RS05890	COG0444	Belongs to the ABC transporter superfamily
AN935_RS05895	COG4608	Belongs to the ABC transporter superfamily
AN935_RS05905	COG0601	transmembrane transport
AN935_RS05910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_RS05920	COG0180	Tryptophanyl-tRNA synthetase
AN935_RS05925	COG4166	transmembrane transport
AN935_RS05930	COG0601	transmembrane transport
AN935_RS05935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_RS05940	COG0444	Belongs to the ABC transporter superfamily
AN935_RS05945	COG4608	Belongs to the ABC transporter superfamily
AN935_RS05950	COG2814	Major facilitator Superfamily
AN935_RS05955	COG0456	acetyltransferase
AN935_RS05960	COG1393	Belongs to the ArsC family
AN935_RS05965	COG0861	Integral membrane protein TerC family
AN935_RS05970	COG4862	establishment of competence for transformation
AN935_RS05975	COG4469	Competence protein
AN935_RS05980	COG1164	Oligoendopeptidase f
AN935_RS05995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AN935_RS06000	COG2346	COG2346, Truncated hemoglobins
AN935_RS06005	COG0741	lytic transglycosylase activity
AN935_RS06010	COG4116	CYTH
AN935_RS06020	COG2357	RelA SpoT domain protein
AN935_RS06025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN935_RS06030	COG0564	pseudouridine synthase activity
AN935_RS06035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN935_RS06040	COG0569	domain protein
AN935_RS06040	COG0475	glutathione-regulated potassium exporter activity
AN935_RS06045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN935_RS06050	COG0352	thiamine-phosphate diphosphorylase activity
AN935_RS06055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_RS06060	COG2104	thiamine diphosphate biosynthetic process
AN935_RS06065	COG2022	thiamine diphosphate biosynthetic process
AN935_RS06070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN935_RS06075	COG0351	phosphomethylpyrimidine kinase
AN935_RS06080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AN935_RS06140	COG0210	DNA helicase
AN935_RS06150	COG2153	protein acetylation
AN935_RS06155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AN935_RS06160	COG2382	esterase
AN935_RS06165	COG0626	cystathionine gamma-synthase activity
AN935_RS06170	COG0626	cystathionine gamma-synthase activity
AN935_RS06175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS06180	COG5505	Protein of unknown function (DUF819)
AN935_RS06190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN935_RS06195	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS06205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS06205	COG3711	transcriptional antiterminator
AN935_RS06210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS06210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_RS06210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_RS06215	COG1482	cell wall glycoprotein biosynthetic process
AN935_RS06230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS06240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN935_RS06255	COG0109	protoheme IX farnesyltransferase activity
AN935_RS06265	COG0726	polysaccharide deacetylase
AN935_RS06285	COG5504	Zn-dependent protease
AN935_RS06290	COG2205	protein histidine kinase activity
AN935_RS06300	COG3383	formate dehydrogenase (NAD+) activity
AN935_RS06305	COG2427	Protein of unknown function (DUF1641)
AN935_RS06315	COG1051	belongs to the nudix hydrolase family
AN935_RS06325	COG2124	cytochrome p450
AN935_RS06330	COG1819	glycosyl
AN935_RS06340	COG1587	Uroporphyrinogen-III synthase
AN935_RS06345	COG0390	transport system, permease component
AN935_RS06350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN935_RS06355	COG0697	spore germination
AN935_RS06360	COG4297	protein containing double-stranded beta helix domain
AN935_RS06370	COG1252	NADH dehydrogenase
AN935_RS06375	COG1904	glucuronate isomerase
AN935_RS06380	COG2211	Major facilitator Superfamily
AN935_RS06385	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AN935_RS06390	COG1063	alcohol dehydrogenase
AN935_RS06395	COG1312	Catalyzes the dehydration of D-mannonate
AN935_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS06405	COG2271	Major facilitator Superfamily
AN935_RS06410	COG1609	Transcriptional regulator
AN935_RS06415	COG0246	Mannitol dehydrogenase
AN935_RS06420	COG2721	sulfolactate sulfo-lyase activity
AN935_RS06425	COG0730	response to heat
AN935_RS06430	COG2318	DinB family
AN935_RS06435	COG0457	Tetratricopeptide repeat
AN935_RS06445	COG2350	Protein conserved in bacteria
AN935_RS06450	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_RS06450	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS06450	COG1388	LysM domain
AN935_RS06460	COG4195	phage-related replication protein
AN935_RS06465	COG3546	catalase activity
AN935_RS06470	COG2856	Zn peptidase
AN935_RS06475	COG1396	sequence-specific DNA binding
AN935_RS06485	COG1522	sequence-specific DNA binding
AN935_RS06490	COG1484	DNA-dependent DNA replication
AN935_RS06515	COG1595	DNA-templated transcription, initiation
AN935_RS06520	COG5484	DNA packaging
AN935_RS06520	COG3728	DNA packaging
AN935_RS06525	COG1783	phage Terminase large subunit
AN935_RS06530	COG5518	Phage portal protein
AN935_RS06535	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AN935_RS06540	COG4653	Phage capsid family
AN935_RS06590	COG3953	SLT domain
AN935_RS06590	COG5412	phage tail tape measure protein
AN935_RS06595	COG1652	LysM domain
AN935_RS06600	COG4193	domain, Protein
AN935_RS06610	COG3628	GPW Gp25 family protein
AN935_RS06615	COG3299	homolog of phage Mu protein gp47
AN935_RS06620	COG3778	Protein conserved in bacteria
AN935_RS06660	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_RS06660	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS06675	COG0306	phosphate transporter
AN935_RS06680	COG1392	Phosphate transport regulator
AN935_RS06685	COG0531	amino acid
AN935_RS06690	COG0346	lactoylglutathione lyase activity
AN935_RS06695	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AN935_RS06700	COG0463	Glycosyl transferase, family 2
AN935_RS06710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_RS06715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN935_RS06720	COG2362	D-Aminopeptidase
AN935_RS06725	COG0601	transmembrane transport
AN935_RS06730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_RS06735	COG0444	Belongs to the ABC transporter superfamily
AN935_RS06740	COG4166	transmembrane transport
AN935_RS06745	COG1619	proteins homologs of microcin C7 resistance protein MccF
AN935_RS06750	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_RS06755	COG0791	NLP P60 protein
AN935_RS06760	COG4608	Belongs to the ABC transporter superfamily
AN935_RS06765	COG2706	6-phosphogluconolactonase activity
AN935_RS06770	COG1834	amidinotransferase
AN935_RS06775	COG1607	acyl-coa hydrolase
AN935_RS06780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN935_RS06780	COG1017	nitric oxide dioxygenase activity
AN935_RS06790	COG2323	membrane
AN935_RS06795	COG2318	DinB family
AN935_RS06800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS06805	COG2076	Multidrug Resistance protein
AN935_RS06810	COG2076	Multidrug Resistance protein
AN935_RS06815	COG0788	formyltetrahydrofolate deformylase activity
AN935_RS06820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AN935_RS06825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AN935_RS06830	COG1764	response to oxidative stress
AN935_RS06835	COG1846	Transcriptional regulator
AN935_RS06840	COG1764	response to oxidative stress
AN935_RS06845	COG0457	Tetratricopeptide repeat
AN935_RS06845	COG0463	Glycosyl transferase, family 2
AN935_RS06850	COG0590	tRNA wobble adenosine to inosine editing
AN935_RS06860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN935_RS06865	COG1404	Belongs to the peptidase S8 family
AN935_RS06870	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS06875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AN935_RS06880	COG1122	ATPase activity
AN935_RS06885	COG4721	ABC-type cobalt transport system, permease component
AN935_RS06895	COG0745	RESPONSE REGULATOR receiver
AN935_RS06900	COG3850	Histidine kinase
AN935_RS06900	COG5002	protein histidine kinase activity
AN935_RS06905	COG3212	peptidase
AN935_RS06910	COG3212	peptidase
AN935_RS06925	COG2239	Acts as a magnesium transporter
AN935_RS06930	COG0789	Transcriptional regulator
AN935_RS06945	COG1846	Transcriptional regulator
AN935_RS06950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN935_RS06955	COG0726	polysaccharide deacetylase
AN935_RS06960	COG1408	metallophosphoesterase
AN935_RS06970	COG0463	Glycosyl transferase, family 2
AN935_RS06975	COG1793	dna ligase
AN935_RS06975	COG3285	dna ligase
AN935_RS06980	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AN935_RS06985	COG3300	MHYT domain
AN935_RS06985	COG5001	Diguanylate cyclase
AN935_RS06990	COG0586	Pfam SNARE associated Golgi protein
AN935_RS06995	COG0861	Integral membrane protein TerC family
AN935_RS07000	COG1191	sigma factor activity
AN935_RS07020	COG0501	Belongs to the peptidase M48B family
AN935_RS07025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN935_RS07040	COG3594	Acyltransferase
AN935_RS07045	COG5002	protein histidine kinase activity
AN935_RS07050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN935_RS07060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AN935_RS07065	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AN935_RS07070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN935_RS07075	COG0436	Aminotransferase
AN935_RS07080	COG1850	ribulose-bisphosphate carboxylase activity
AN935_RS07085	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AN935_RS07090	COG0235	Class ii aldolase
AN935_RS07095	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AN935_RS07100	COG3339	Conserved Protein
AN935_RS07115	COG3852	Histidine kinase
AN935_RS07120	COG1846	Transcriptional regulator
AN935_RS07125	COG1360	Flagellar Motor Protein
AN935_RS07130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AN935_RS07135	COG0542	response to heat
AN935_RS07140	COG3949	Membrane
AN935_RS07145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AN935_RS07150	COG0720	synthase
AN935_RS07155	COG0602	queuosine metabolic process
AN935_RS07160	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AN935_RS07165	COG1388	LysM domain
AN935_RS07165	COG4641	Protein conserved in bacteria
AN935_RS07170	COG1388	LysM domain
AN935_RS07175	COG3858	chitin binding
AN935_RS07190	COG4873	Protein conserved in bacteria
AN935_RS07205	COG3773	Cell wall hydrolase
AN935_RS07210	COG2244	polysaccharide biosynthetic process
AN935_RS07215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS07220	COG2217	Heavy metal translocating P-type atpase
AN935_RS07230	COG0006	proline dipeptidase activity
AN935_RS07240	COG1609	Transcriptional regulator
AN935_RS07245	COG3711	transcriptional antiterminator
AN935_RS07250	COG2190	(PTS) system
AN935_RS07250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS07250	COG1263	PTS System
AN935_RS07255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS07260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN935_RS07270	COG1533	DNA photolyase activity
AN935_RS07275	COG0456	acetyltransferase
AN935_RS07280	COG0840	transmembrane signaling receptor activity
AN935_RS07285	COG2084	Dehydrogenase
AN935_RS07295	COG2340	Cysteine-rich secretory protein family
AN935_RS07300	COG0768	penicillin binding
AN935_RS07305	COG4191	Histidine kinase
AN935_RS07310	COG0436	Aminotransferase
AN935_RS07320	COG0835	chemotaxis
AN935_RS07320	COG0784	Response regulator, receiver
AN935_RS07330	COG2814	Major facilitator Superfamily
AN935_RS07335	COG1376	ErfK ybiS ycfS ynhG family protein
AN935_RS07340	COG1408	metallophosphoesterase
AN935_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS07350	COG2200	EAL domain
AN935_RS07360	COG4703	Protein of unknown function (DUF1797)
AN935_RS07365	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AN935_RS07375	COG0517	IMP dehydrogenase activity
AN935_RS07380	COG0583	DNA-binding transcription factor activity
AN935_RS07385	COG0716	FMN binding
AN935_RS07395	COG0716	FMN binding
AN935_RS07400	COG2171	N-acyltransferase activity
AN935_RS07405	COG1473	amidohydrolase
AN935_RS07415	COG0668	transmembrane transport
AN935_RS07420	COG0450	alkyl hydroperoxide reductase
AN935_RS07425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS07440	COG0746	molybdenum cofactor guanylyltransferase activity
AN935_RS07445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AN935_RS07450	COG0303	'Molybdopterin
AN935_RS07455	COG1763	Mo-molybdopterin cofactor biosynthetic process
AN935_RS07460	COG0314	molybdopterin synthase activity
AN935_RS07465	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AN935_RS07470	COG1132	(ABC) transporter
AN935_RS07475	COG1132	(ABC) transporter
AN935_RS07485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN935_RS07490	COG1136	(ABC) transporter
AN935_RS07495	COG0577	efflux transmembrane transporter activity
AN935_RS07500	COG1349	DNA-binding transcription factor activity
AN935_RS07505	COG1105	Belongs to the carbohydrate kinase PfkB family
AN935_RS07510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_RS07510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN935_RS07510	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS07515	COG0681	Belongs to the peptidase S26 family
AN935_RS07525	COG0488	(ABC) transporter
AN935_RS07530	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AN935_RS07535	COG2309	aminopeptidase activity
AN935_RS07545	COG1077	Cell shape determining protein MreB Mrl
AN935_RS07550	COG2002	toxin-antitoxin pair type II binding
AN935_RS07555	COG3852	Histidine kinase
AN935_RS07560	COG2105	PFAM AIG2 family protein
AN935_RS07560	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AN935_RS07565	COG0569	domain protein
AN935_RS07570	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AN935_RS07575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AN935_RS07580	COG5503	Protein of unknown function (DUF1447)
AN935_RS07585	COG0561	phosphatase activity
AN935_RS07590	COG0242	peptide deformylase activity
AN935_RS07600	COG0497	DNA recombination
AN935_RS07605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN935_RS07610	COG0022	dehydrogenase e1 component
AN935_RS07615	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_RS07620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN935_RS07625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS07630	COG1982	Orn Lys Arg decarboxylase major
AN935_RS07635	COG4476	Belongs to the UPF0223 family
AN935_RS07640	COG4493	Belongs to the UPF0637 family
AN935_RS07650	COG0483	inositol monophosphate 1-phosphatase activity
AN935_RS07665	COG0657	acetylesterase activity
AN935_RS07670	COG1959	2 iron, 2 sulfur cluster binding
AN935_RS07690	COG1595	DNA-templated transcription, initiation
AN935_RS07710	COG1217	gtp-binding protein TYPA
AN935_RS07720	COG4896	Protein conserved in bacteria
AN935_RS07730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AN935_RS07735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN935_RS07740	COG2066	Belongs to the glutaminase family
AN935_RS07745	COG4838	Belongs to the UPF0358 family
AN935_RS07750	COG0772	Belongs to the SEDS family
AN935_RS07755	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AN935_RS07765	COG1612	heme a metabolic process
AN935_RS07770	COG0109	protoheme IX farnesyltransferase activity
AN935_RS07775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN935_RS07775	COG2010	Cytochrome c
AN935_RS07780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AN935_RS07785	COG1845	cytochrome c oxidase, subunit III
AN935_RS07790	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AN935_RS07795	COG3336	cytochrome c oxidase
AN935_RS07805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AN935_RS07810	COG2340	Cysteine-rich secretory protein family
AN935_RS07825	COG3679	Belongs to the UPF0342 family
AN935_RS07830	COG4471	UPF0298 protein
AN935_RS07835	COG0742	ribosomal rna small subunit methyltransferase
AN935_RS07840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AN935_RS07845	COG3314	Sporulation integral membrane protein YlbJ
AN935_RS07850	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN935_RS07855	COG3480	Lon protease (S16) C-terminal proteolytic domain
AN935_RS07860	COG1323	Belongs to the UPF0348 family
AN935_RS07870	COG1399	metal-binding, possibly nucleic acid-binding protein
AN935_RS07885	COG0454	-acetyltransferase
AN935_RS07890	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AN935_RS07895	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AN935_RS07900	COG2001	Belongs to the MraZ family
AN935_RS07905	COG0275	rRNA processing
AN935_RS07910	COG4839	cell division protein FtsL
AN935_RS07915	COG0768	penicillin binding
AN935_RS07925	COG0768	penicillin binding
AN935_RS07930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN935_RS07940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN935_RS07945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AN935_RS07950	COG0772	Belongs to the SEDS family
AN935_RS07955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN935_RS07960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AN935_RS07965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AN935_RS07970	COG3879	Bacterial protein of unknown function (DUF881)
AN935_RS07975	COG3879	Bacterial protein of unknown function (DUF881)
AN935_RS07980	COG3856	small basic protein
AN935_RS07985	COG0849	cell division
AN935_RS07990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN935_RS07995	COG1404	Belongs to the peptidase S8 family
AN935_RS07995	COG4412	M6 family metalloprotease domain protein
AN935_RS08005	COG1191	sigma factor activity
AN935_RS08010	COG1191	sigma factor activity
AN935_RS08015	COG1119	ATPase activity
AN935_RS08020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_RS08025	COG1873	PFAM PRC-barrel domain
AN935_RS08030	COG1496	oxidoreductase activity
AN935_RS08035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AN935_RS08040	COG1799	cell septum assembly
AN935_RS08045	COG0762	integral membrane protein
AN935_RS08050	COG2302	S4 RNA-binding domain
AN935_RS08055	COG3599	regulation of cell shape
AN935_RS08060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AN935_RS08065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN935_RS08070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AN935_RS08075	COG0564	pseudouridine synthase activity
AN935_RS08080	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AN935_RS08085	COG2233	PERMEase
AN935_RS08090	COG0540	Belongs to the ATCase OTCase family
AN935_RS08095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AN935_RS08100	COG0505	Belongs to the CarA family
AN935_RS08105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AN935_RS08110	COG0543	2 iron, 2 sulfur cluster binding
AN935_RS08115	COG0167	dihydroorotate dehydrogenase activity
AN935_RS08120	COG0284	orotidine-5'-phosphate decarboxylase activity
AN935_RS08125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AN935_RS08130	COG0175	sulfate reduction
AN935_RS08135	COG0306	phosphate transporter
AN935_RS08140	COG2046	Belongs to the sulfate adenylyltransferase family
AN935_RS08145	COG0529	Catalyzes the synthesis of activated sulfate
AN935_RS08150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN935_RS08155	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AN935_RS08160	COG1648	precorrin-2 dehydrogenase activity
AN935_RS08165	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AN935_RS08170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AN935_RS08175	COG1561	YicC-like family, N-terminal region
AN935_RS08185	COG0194	GDP metabolic process
AN935_RS08190	COG1758	RNA polymerase activity
AN935_RS08195	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN935_RS08200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN935_RS08205	COG0242	peptide deformylase activity
AN935_RS08210	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AN935_RS08215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN935_RS08215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AN935_RS08220	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AN935_RS08225	COG0631	protein serine/threonine phosphatase activity
AN935_RS08230	COG0515	serine threonine protein kinase
AN935_RS08230	COG2815	serine threonine protein kinase
AN935_RS08235	COG1162	GTPase activity
AN935_RS08240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AN935_RS08245	COG1564	THIamine pyrophosphokinase
AN935_RS08255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AN935_RS08260	COG1302	Protein conserved in bacteria
AN935_RS08265	COG1461	Dihydroxyacetone kinase
AN935_RS08270	COG1760	l-serine dehydratase
AN935_RS08275	COG1760	l-serine dehydratase
AN935_RS08280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN935_RS08285	COG2050	protein possibly involved in aromatic compounds catabolism
AN935_RS08285	COG1349	DNA-binding transcription factor activity
AN935_RS08290	COG0416	fatty acid biosynthetic process
AN935_RS08295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN935_RS08300	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS08310	COG0571	ribonuclease III activity
AN935_RS08315	COG1196	nuclear chromosome segregation
AN935_RS08320	COG0552	protein localization to endoplasmic reticulum
AN935_RS08330	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AN935_RS08335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN935_RS08340	COG0228	four-way junction DNA binding
AN935_RS08345	COG1837	Belongs to the UPF0109 family
AN935_RS08355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN935_RS08360	COG0336	Belongs to the RNA methyltransferase TrmD family
AN935_RS08365	COG0335	large ribosomal subunit rRNA binding
AN935_RS08370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AN935_RS08375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN935_RS08385	COG2257	FlhB HrpN YscU SpaS Family
AN935_RS08390	COG0045	succinate-CoA ligase (ADP-forming) activity
AN935_RS08395	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AN935_RS08400	COG0758	DNA mediated transformation
AN935_RS08405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AN935_RS08410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AN935_RS08415	COG4974	Belongs to the 'phage' integrase family
AN935_RS08420	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AN935_RS08425	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AN935_RS08430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AN935_RS08435	COG1815	bacterial-type flagellum-dependent cell motility
AN935_RS08440	COG1558	bacterial-type flagellum-dependent cell motility
AN935_RS08445	COG1677	Flagellar hook-basal body complex protein FliE
AN935_RS08450	COG1766	The M ring may be actively involved in energy transduction
AN935_RS08455	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN935_RS08460	COG1317	bacterial-type flagellum organization
AN935_RS08465	COG1157	protein secretion by the type III secretion system
AN935_RS08470	COG2882	bacterial-type flagellum organization
AN935_RS08475	COG3334	PFAM MgtE intracellular
AN935_RS08480	COG3144	bacterial-type flagellum assembly
AN935_RS08485	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AN935_RS08490	COG4786	Flagellar basal body rod
AN935_RS08495	COG1582	Flagellar protein (FlbD)
AN935_RS08500	COG1580	Controls the rotational direction of flagella during chemotaxis
AN935_RS08505	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN935_RS08510	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AN935_RS08510	COG1776	CheC inhibitor of MCP methylation
AN935_RS08515	COG2201	protein-glutamate methylesterase activity
AN935_RS08520	COG3190	flagellar
AN935_RS08525	COG1338	Plays a role in the flagellum-specific transport system
AN935_RS08530	COG1987	bacterial-type flagellum assembly
AN935_RS08535	COG1684	flagellar biosynthetic protein fliR
AN935_RS08540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AN935_RS08545	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AN935_RS08550	COG1419	protein localization to endoplasmic reticulum
AN935_RS08555	COG0455	bacterial-type flagellum organization
AN935_RS08560	COG2201	protein-glutamate methylesterase activity
AN935_RS08565	COG2198	Histidine kinase
AN935_RS08565	COG0643	Histidine kinase
AN935_RS08570	COG0835	chemotaxis
AN935_RS08575	COG1776	CheC inhibitor of MCP methylation
AN935_RS08580	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AN935_RS08585	COG1191	sigma factor activity
AN935_RS08595	COG0052	Belongs to the universal ribosomal protein uS2 family
AN935_RS08600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AN935_RS08605	COG0528	UMP kinase activity
AN935_RS08610	COG0233	cytoplasmic translational termination
AN935_RS08615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN935_RS08620	COG4589	Belongs to the CDS family
AN935_RS08625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AN935_RS08630	COG0750	zinc metalloprotease
AN935_RS08635	COG0442	prolyl-tRNA aminoacylation
AN935_RS08640	COG2176	DNA-directed DNA polymerase activity
AN935_RS08645	COG0779	Required for maturation of 30S ribosomal subunits
AN935_RS08650	COG0195	Participates in both transcription termination and antitermination
AN935_RS08655	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AN935_RS08660	COG1358	cellular component organization or biogenesis
AN935_RS08665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AN935_RS08670	COG1550	Protein conserved in bacteria
AN935_RS08675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AN935_RS08680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN935_RS08685	COG0196	riboflavin kinase activity
AN935_RS08695	COG1185	polyribonucleotide nucleotidyltransferase activity
AN935_RS08700	COG0726	polysaccharide deacetylase
AN935_RS08705	COG0612	Peptidase, M16
AN935_RS08710	COG1873	PFAM PRC-barrel domain
AN935_RS08720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN935_RS08725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN935_RS08730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AN935_RS08735	COG0527	aspartate kinase activity
AN935_RS08740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN935_RS08745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AN935_RS08750	COG0740	serine-type endopeptidase activity
AN935_RS08760	COG1674	ftsk spoiiie
AN935_RS08760	COG4980	gas vesicle protein
AN935_RS08765	COG2188	Transcriptional regulator
AN935_RS08770	COG2814	Major facilitator Superfamily
AN935_RS08775	COG0612	Peptidase, M16
AN935_RS08780	COG0612	Peptidase, M16
AN935_RS08785	COG0300	oxidoreductase activity
AN935_RS08800	COG1426	Protein conserved in bacteria
AN935_RS08805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AN935_RS08810	COG1546	Belongs to the CinA family
AN935_RS08810	COG1058	Belongs to the CinA family
AN935_RS08815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AN935_RS08820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN935_RS08825	COG1418	mRNA catabolic process
AN935_RS08830	COG1692	metallophosphoesterase
AN935_RS08835	COG2359	stage V sporulation protein S
AN935_RS08840	COG1063	alcohol dehydrogenase
AN935_RS08845	COG0156	8-amino-7-oxononanoate synthase activity
AN935_RS08850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN935_RS08855	COG4550	Control of competence regulator ComK, YlbF/YmcA
AN935_RS08865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AN935_RS08870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN935_RS08905	COG3226	Transcriptional regulator
AN935_RS08915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS08920	COG1404	Belongs to the peptidase S8 family
AN935_RS08930	COG4195	phage-related replication protein
AN935_RS08935	COG1764	response to oxidative stress
AN935_RS08960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AN935_RS08965	COG1923	regulation of RNA biosynthetic process
AN935_RS08980	COG1780	Probably involved in ribonucleotide reductase function
AN935_RS08985	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN935_RS08990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN935_RS08995	COG4112	unkown
AN935_RS09000	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_RS09005	COG0464	growth
AN935_RS09015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN935_RS09020	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AN935_RS09025	COG0789	Transcriptional regulator
AN935_RS09030	COG0174	glutamine synthetase
AN935_RS09055	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN935_RS09060	COG1733	regulation of RNA biosynthetic process
AN935_RS09090	COG0135	phosphoribosylanthranilate isomerase activity
AN935_RS09115	COG2211	Major facilitator Superfamily
AN935_RS09120	COG3507	Belongs to the glycosyl hydrolase 43 family
AN935_RS09135	COG1070	Carbohydrate kinase
AN935_RS09145	COG1525	nuclease
AN935_RS09150	COG2814	Major facilitator Superfamily
AN935_RS09160	COG0756	dUTP diphosphatase activity
AN935_RS09205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AN935_RS09215	COG3832	glyoxalase III activity
AN935_RS09230	COG2059	Chromate
AN935_RS09235	COG0697	spore germination
AN935_RS09240	COG0531	amino acid
AN935_RS09270	COG4195	phage-related replication protein
AN935_RS09280	COG0346	lactoylglutathione lyase activity
AN935_RS09290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN935_RS09295	COG1388	LysM domain
AN935_RS09300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AN935_RS09305	COG4224	UPF0291 protein
AN935_RS09310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN935_RS09320	COG3763	UPF0154 protein
AN935_RS09330	COG0785	Cytochrome C biogenesis protein
AN935_RS09335	COG2201	protein-glutamate methylesterase activity
AN935_RS09340	COG4846	Membrane protein involved in cytochrome C biogenesis
AN935_RS09350	COG0071	Belongs to the small heat shock protein (HSP20) family
AN935_RS09365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AN935_RS09370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS09390	COG0824	Thioesterase
AN935_RS09400	COG4841	protein insertion into membrane
AN935_RS09405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AN935_RS09410	COG1832	CoA-binding protein
AN935_RS09415	COG0187	DNA topoisomerase II activity
AN935_RS09420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN935_RS09435	COG1115	amino acid carrier protein
AN935_RS09450	COG5520	Belongs to the glycosyl hydrolase 30 family
AN935_RS09475	COG2246	polysaccharide biosynthetic process
AN935_RS09480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN935_RS09485	COG0586	Pfam SNARE associated Golgi protein
AN935_RS09490	COG2404	hydrolase activity, acting on ester bonds
AN935_RS09495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN935_RS09500	COG1024	Enoyl-CoA hydratase
AN935_RS09505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN935_RS09510	COG0511	ligase activity, forming carbon-carbon bonds
AN935_RS09515	COG0439	Biotin carboxylase
AN935_RS09520	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_RS09525	COG1960	acyl-CoA dehydrogenase activity
AN935_RS09545	COG1649	PFAM Uncharacterised BCR, COG1649
AN935_RS09555	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN935_RS09555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS09565	COG2027	D-alanyl-D-alanine carboxypeptidase
AN935_RS09570	COG2017	converts alpha-aldose to the beta-anomer
AN935_RS09575	COG0534	Mate efflux family protein
AN935_RS09590	COG0582	viral genome integration into host DNA
AN935_RS09595	COG0166	Belongs to the GPI family
AN935_RS09600	COG0405	Gamma-glutamyltransferase
AN935_RS09605	COG0583	DNA-binding transcription factor activity
AN935_RS09610	COG0604	alcohol dehydrogenase
AN935_RS09615	COG0493	'glutamate synthase
AN935_RS09620	COG0067	glutamate synthase
AN935_RS09620	COG0069	glutamate synthase activity
AN935_RS09620	COG0070	glutamate synthase
AN935_RS09625	COG0583	DNA-binding transcription factor activity
AN935_RS09630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AN935_RS09645	COG0300	oxidoreductase activity
AN935_RS09650	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AN935_RS09660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS09665	COG2814	Major facilitator Superfamily
AN935_RS09670	COG1070	Carbohydrate kinase
AN935_RS09675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN935_RS09680	COG0243	molybdopterin cofactor binding
AN935_RS09695	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS09710	COG5278	phosphoserine phosphatase activity
AN935_RS09710	COG0840	transmembrane signaling receptor activity
AN935_RS09715	COG2368	4-hydroxyphenylacetate
AN935_RS09720	COG4305	rare lipoprotein A
AN935_RS09725	COG3619	membrane
AN935_RS09750	COG2135	peptidase activity
AN935_RS09760	COG2140	Oxalate decarboxylase
AN935_RS09770	COG0457	Tetratricopeptide repeat
AN935_RS09795	COG2720	vancomycin resistance protein
AN935_RS09810	COG3739	integral membrane protein
AN935_RS09815	COG0583	DNA-binding transcription factor activity
AN935_RS09820	COG0697	spore germination
AN935_RS09830	COG1388	LysM domain
AN935_RS09840	COG0693	protein deglycase activity
AN935_RS09845	COG2367	Beta-lactamase
AN935_RS09850	COG4282	regulation of fungal-type cell wall biogenesis
AN935_RS09855	COG3397	chitin binding
AN935_RS09860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN935_RS09865	COG3848	Pyruvate phosphate dikinase
AN935_RS09865	COG0574	Belongs to the PEP-utilizing enzyme family
AN935_RS09875	COG4282	regulation of fungal-type cell wall biogenesis
AN935_RS09880	COG1231	oxidoreductase activity
AN935_RS09885	COG0726	polysaccharide deacetylase
AN935_RS09950	COG3655	Transcriptional regulator
AN935_RS09990	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AN935_RS09995	COG0463	Glycosyl transferase, family 2
AN935_RS10000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS10005	COG2274	protein secretion by the type I secretion system
AN935_RS10005	COG3271	cysteine-type peptidase activity
AN935_RS10020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN935_RS10075	COG1404	Belongs to the peptidase S8 family
AN935_RS10085	COG1404	Belongs to the peptidase S8 family
AN935_RS10095	COG1136	(ABC) transporter
AN935_RS10095	COG0577	efflux transmembrane transporter activity
AN935_RS10110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_RS10115	COG2207	Transcriptional regulator
AN935_RS10115	COG0662	Cupin 2, conserved barrel domain protein
AN935_RS10120	COG0456	acetyltransferase
AN935_RS10125	COG1309	transcriptional regulator
AN935_RS10130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS10135	COG3708	Transcriptional regulator
AN935_RS10140	COG2378	regulation of single-species biofilm formation
AN935_RS10150	COG0640	Transcriptional regulator
AN935_RS10155	COG0741	lytic transglycosylase activity
AN935_RS10160	COG2322	membrane
AN935_RS10175	COG1619	proteins homologs of microcin C7 resistance protein MccF
AN935_RS10180	COG3239	Fatty acid desaturase
AN935_RS10185	COG4585	Histidine kinase
AN935_RS10190	COG2197	response regulator
AN935_RS10195	COG3584	3D domain protein
AN935_RS10195	COG1388	LysM domain
AN935_RS10200	COG0514	ATP-dependent DNA helicase (RecQ)
AN935_RS10210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN935_RS10215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN935_RS10230	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS10235	COG1657	PFAM Prenyltransferase squalene oxidase
AN935_RS10240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN935_RS10245	COG0733	neurotransmitter:sodium symporter activity
AN935_RS10250	COG0385	Bile acid
AN935_RS10255	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_RS10260	COG0567	Dehydrogenase, E1 component
AN935_RS10265	COG4548	von Willebrand factor, type A
AN935_RS10270	COG0714	Associated with various cellular activities
AN935_RS10275	COG2032	superoxide dismutase activity
AN935_RS10280	COG0791	NLP P60 protein
AN935_RS10280	COG1388	LysM domain
AN935_RS10285	COG1819	glycosyl
AN935_RS10290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AN935_RS10295	COG0534	Mate efflux family protein
AN935_RS10300	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS10305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN935_RS10310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN935_RS10320	COG2962	Rard protein
AN935_RS10335	COG2610	gluconate transmembrane transporter activity
AN935_RS10340	COG1942	4-Oxalocrotonate Tautomerase
AN935_RS10350	COG1733	regulation of RNA biosynthetic process
AN935_RS10355	COG0778	Nitroreductase
AN935_RS10360	COG0400	carboxylic ester hydrolase activity
AN935_RS10365	COG0346	lactoylglutathione lyase activity
AN935_RS10375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_RS10380	COG0793	Belongs to the peptidase S41A family
AN935_RS10380	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS10385	COG2226	methyltransferase
AN935_RS10395	COG1876	peptidase activity
AN935_RS10400	COG0813	purine-nucleoside phosphorylase activity
AN935_RS10415	COG0671	phosphoesterase, PA-phosphatase related
AN935_RS10440	COG4479	Belongs to the UPF0346 family
AN935_RS10450	COG1509	lysine 2,3-aminomutase activity
AN935_RS10455	COG0456	acetyltransferase
AN935_RS10460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_RS10465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN935_RS10470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN935_RS10475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AN935_RS10490	COG0456	acetyltransferase
AN935_RS10495	COG0463	Glycosyl transferase, family 2
AN935_RS10510	COG4641	Protein conserved in bacteria
AN935_RS10515	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
AN935_RS10520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN935_RS10530	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN935_RS10535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AN935_RS10540	COG1846	Transcriptional regulator
AN935_RS10545	COG0534	Mate efflux family protein
AN935_RS10555	COG4698	Protein conserved in bacteria
AN935_RS10560	COG2755	lipolytic protein G-D-S-L family
AN935_RS10565	COG1999	signal sequence binding
AN935_RS10575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN935_RS10580	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AN935_RS10585	COG1272	protein, Hemolysin III
AN935_RS10590	COG0204	Acyl-transferase
AN935_RS10595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN935_RS10605	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN935_RS10615	COG2521	methyltransferase
AN935_RS10615	COG2136	Putative SAM-dependent methyltransferase
AN935_RS10625	COG0129	dihydroxy-acid dehydratase activity
AN935_RS10630	COG1413	lyase activity
AN935_RS10635	COG1418	mRNA catabolic process
AN935_RS10640	COG0386	Belongs to the glutathione peroxidase family
AN935_RS10645	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AN935_RS10650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AN935_RS10655	COG1278	Cold shock
AN935_RS10675	COG0328	RNA-DNA hybrid ribonuclease activity
AN935_RS10680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AN935_RS10685	COG0328	RNA-DNA hybrid ribonuclease activity
AN935_RS10695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN935_RS10710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AN935_RS10715	COG1755	Isoprenylcysteine carboxyl methyltransferase
AN935_RS10720	COG3424	synthase
AN935_RS10725	COG2233	PERMEase
AN935_RS10730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN935_RS10735	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AN935_RS10745	COG0800	Aldolase
AN935_RS10750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_RS10755	COG1609	Transcriptional regulator
AN935_RS10760	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AN935_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS10770	COG1199	ATP-dependent helicase activity
AN935_RS10780	COG0116	Belongs to the methyltransferase superfamily
AN935_RS10795	COG4474	Belongs to the UPF0398 family
AN935_RS10805	COG3359	exonuclease
AN935_RS10810	COG1111	helicase
AN935_RS10810	COG1205	dead DEAH box helicase
AN935_RS10815	COG2190	(PTS) system
AN935_RS10820	COG0071	Belongs to the small heat shock protein (HSP20) family
AN935_RS10855	COG3331	DNA recombination
AN935_RS10860	COG4499	WXG100 protein secretion system (Wss), protein YukC
AN935_RS10860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_RS10870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN935_RS10875	COG3935	DnaD domain protein
AN935_RS10880	COG0017	Asparaginyl-tRNA synthetase
AN935_RS10885	COG0436	Aminotransferase
AN935_RS10890	COG5353	protein conserved in bacteria
AN935_RS10900	COG1199	ATP-dependent helicase activity
AN935_RS10900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN935_RS10905	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AN935_RS10910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AN935_RS10915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AN935_RS10920	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AN935_RS10920	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AN935_RS10925	COG0617	tRNA 3'-terminal CCA addition
AN935_RS10930	COG0438	transferase activity, transferring glycosyl groups
AN935_RS10935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN935_RS10940	COG1803	Methylglyoxal synthase
AN935_RS10945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AN935_RS10950	COG1694	Mazg nucleotide pyrophosphohydrolase
AN935_RS10955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS10965	COG4347	Protein of unknown function (DUF1405)
AN935_RS10970	COG2010	Cytochrome c
AN935_RS10970	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AN935_RS10975	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AN935_RS10980	COG0723	plastoquinol--plastocyanin reductase activity
AN935_RS10990	COG5582	Belongs to the UPF0302 family
AN935_RS10995	COG0457	Tetratricopeptide repeat
AN935_RS11000	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AN935_RS11005	COG0287	Prephenate dehydrogenase
AN935_RS11010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AN935_RS11015	COG0159	tryptophan synthase activity
AN935_RS11020	COG0133	tryptophan synthase activity
AN935_RS11025	COG0135	phosphoribosylanthranilate isomerase activity
AN935_RS11035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN935_RS11040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN935_RS11045	COG4401	Chorismate mutase type I
AN935_RS11050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AN935_RS11055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AN935_RS11060	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AN935_RS11065	COG0105	UTP biosynthetic process
AN935_RS11070	COG0142	geranyltranstransferase activity
AN935_RS11075	COG2226	methyltransferase
AN935_RS11080	COG0142	geranyltranstransferase activity
AN935_RS11090	COG0302	gtp cyclohydrolase
AN935_RS11095	COG0776	regulation of translation
AN935_RS11100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AN935_RS11115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AN935_RS11120	COG1160	GTP binding
AN935_RS11145	COG1304	FMN binding
AN935_RS11150	COG0539	negative regulation of cytoplasmic translation
AN935_RS11155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN935_RS11165	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
AN935_RS11170	COG2959	enzyme of heme biosynthesis
AN935_RS11175	COG3773	Cell wall hydrolase
AN935_RS11175	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS11180	COG2339	peptidase activity
AN935_RS11185	COG0492	ferredoxin-NADP+ reductase activity
AN935_RS11190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN935_RS11195	COG4862	establishment of competence for transformation
AN935_RS11200	COG1408	metallophosphoesterase
AN935_RS11210	COG1388	LysM domain
AN935_RS11215	COG1266	CAAX protease self-immunity
AN935_RS11220	COG0514	ATP-dependent DNA helicase (RecQ)
AN935_RS11225	COG4955	Helix-turn-helix domain
AN935_RS11230	COG1141	Ferredoxin
AN935_RS11235	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AN935_RS11240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN935_RS11245	COG0710	3-dehydroquinate dehydratase activity
AN935_RS11255	COG1595	DNA-templated transcription, initiation
AN935_RS11260	COG5002	protein histidine kinase activity
AN935_RS11265	COG0745	RESPONSE REGULATOR receiver
AN935_RS11270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN935_RS11275	COG1333	cytochrome c biogenesis protein
AN935_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS11285	COG1187	pseudouridine synthase activity
AN935_RS11290	COG0700	Nucleoside recognition
AN935_RS11295	COG2715	membrane protein required for spore maturation
AN935_RS11300	COG1686	Belongs to the peptidase S11 family
AN935_RS11310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AN935_RS11315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AN935_RS11320	COG1547	Domain of unknown function (DUF309)
AN935_RS11325	COG0456	acetyltransferase
AN935_RS11330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AN935_RS11335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN935_RS11335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN935_RS11340	COG0307	riboflavin synthase, alpha
AN935_RS11345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN935_RS11345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN935_RS11380	COG0534	Mate efflux family protein
AN935_RS11385	COG2226	methyltransferase
AN935_RS11395	COG2070	2-Nitropropane dioxygenase
AN935_RS11395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN935_RS11400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN935_RS11405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS11420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AN935_RS11425	COG3425	synthase
AN935_RS11430	COG1024	Enoyl-CoA hydratase
AN935_RS11435	COG1024	Enoyl-CoA hydratase
AN935_RS11445	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS11450	COG1819	glycosyl
AN935_RS11465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS11480	COG0681	Belongs to the peptidase S26 family
AN935_RS11485	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AN935_RS11495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN935_RS11505	COG4086	secreted protein
AN935_RS11510	COG0019	diaminopimelate decarboxylase activity
AN935_RS11515	COG0697	spore germination
AN935_RS11530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AN935_RS11550	COG1191	sigma factor activity
AN935_RS11560	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS11565	COG1686	Belongs to the peptidase S11 family
AN935_RS11570	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AN935_RS11575	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AN935_RS11580	COG4974	Belongs to the 'phage' integrase family
AN935_RS11590	COG0735	belongs to the Fur family
AN935_RS11595	COG1300	Membrane
AN935_RS11605	COG0281	malic enzyme
AN935_RS11610	COG1757	Na H antiporter
AN935_RS11615	COG1027	Aspartate ammonia-lyase
AN935_RS11620	COG0252	asparaginase activity
AN935_RS11625	COG1396	sequence-specific DNA binding
AN935_RS11630	COG1379	DNA repair
AN935_RS11635	COG0494	nUDIX hydrolase
AN935_RS11645	COG0667	Aldo Keto reductase
AN935_RS11655	COG1073	alpha beta
AN935_RS11665	COG4918	Iron-sulphur cluster biosynthesis
AN935_RS11670	COG0456	acetyltransferase
AN935_RS11670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AN935_RS11675	COG2329	Antibiotic biosynthesis monooxygenase
AN935_RS11680	COG0456	acetyltransferase
AN935_RS11690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN935_RS11715	COG1072	(Pantothenic acid kinase))
AN935_RS11720	COG3048	D-serine ammonia-lyase activity
AN935_RS11725	COG0300	oxidoreductase activity
AN935_RS11730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS11735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN935_RS11740	COG4187	Peptidase family M20/M25/M40
AN935_RS11745	COG1902	pentaerythritol trinitrate reductase activity
AN935_RS11750	COG0596	Alpha beta hydrolase
AN935_RS11760	COG1234	tRNA 3'-trailer cleavage
AN935_RS11765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AN935_RS11770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN935_RS11775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN935_RS11785	COG0706	membrane insertase activity
AN935_RS11790	COG3361	conserved protein (COG2071)
AN935_RS11795	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN935_RS11800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN935_RS11805	COG0346	lactoylglutathione lyase activity
AN935_RS11815	COG1376	ErfK ybiS ycfS ynhG family protein
AN935_RS11820	COG4129	membrane
AN935_RS11825	COG1126	abc transporter atp-binding protein
AN935_RS11830	COG0765	amino acid transport
AN935_RS11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS11845	COG1597	lipid kinase activity
AN935_RS11850	COG2814	Major facilitator Superfamily
AN935_RS11855	COG0789	Transcriptional regulator
AN935_RS11855	COG4978	Transcriptional regulator
AN935_RS11860	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN935_RS11865	COG0022	dehydrogenase e1 component
AN935_RS11880	COG3426	butyrate kinase activity
AN935_RS11885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN935_RS11890	COG0280	phosphate acetyltransferase
AN935_RS11895	COG3829	transcription factor binding
AN935_RS11895	COG3290	protein histidine kinase activity
AN935_RS11905	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AN935_RS11910	COG2079	MmgE PrpD family protein
AN935_RS11915	COG0372	Belongs to the citrate synthase family
AN935_RS11920	COG1960	acyl-CoA dehydrogenase activity
AN935_RS11925	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN935_RS11930	COG0183	Belongs to the thiolase family
AN935_RS11935	COG0584	glycerophosphoryl diester phosphodiesterase
AN935_RS11940	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_RS11955	COG1902	pentaerythritol trinitrate reductase activity
AN935_RS11965	COG0745	RESPONSE REGULATOR receiver
AN935_RS11975	COG0750	zinc metalloprotease
AN935_RS11980	COG0497	DNA recombination
AN935_RS11985	COG1438	arginine binding
AN935_RS11990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AN935_RS11995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AN935_RS12000	COG0142	geranyltranstransferase activity
AN935_RS12005	COG1722	exodeoxyribonuclease VII activity
AN935_RS12010	COG1570	exodeoxyribonuclease VII activity
AN935_RS12015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AN935_RS12020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AN935_RS12025	COG1302	Protein conserved in bacteria
AN935_RS12030	COG0439	Biotin carboxylase
AN935_RS12035	COG0511	ligase activity, forming carbon-carbon bonds
AN935_RS12075	COG3854	ATPases associated with a variety of cellular activities
AN935_RS12085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AN935_RS12090	COG0006	proline dipeptidase activity
AN935_RS12095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AN935_RS12105	COG3872	metal-dependent enzyme
AN935_RS12115	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN935_RS12120	COG1321	iron dependent repressor
AN935_RS12125	COG0095	Lipoate-protein ligase
AN935_RS12130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_RS12135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN935_RS12140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AN935_RS12145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AN935_RS12150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN935_RS12165	COG1396	sequence-specific DNA binding
AN935_RS12175	COG0681	Belongs to the peptidase S26 family
AN935_RS12200	COG4940	Competence protein ComGF
AN935_RS12210	COG4970	Tfp pilus assembly protein FimT
AN935_RS12215	COG4537	Required for transformation and DNA binding
AN935_RS12220	COG1459	type II secretion system
AN935_RS12225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN935_RS12235	COG0517	IMP dehydrogenase activity
AN935_RS12240	COG0598	Magnesium transport protein CorA
AN935_RS12245	COG1253	flavin adenine dinucleotide binding
AN935_RS12250	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS12260	COG1393	Belongs to the ArsC family
AN935_RS12270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS12280	COG0011	TIGRFAM Protein of
AN935_RS12290	COG2866	Carboxypeptidase
AN935_RS12295	COG1368	sulfuric ester hydrolase activity
AN935_RS12300	COG1940	carbohydrate kinase activity
AN935_RS12305	COG4483	Protein conserved in bacteria
AN935_RS12310	COG0457	Tetratricopeptide repeat
AN935_RS12310	COG0705	Rhomboid family
AN935_RS12320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN935_RS12330	COG0438	transferase activity, transferring glycosyl groups
AN935_RS12345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN935_RS12350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN935_RS12355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN935_RS12360	COG0581	inorganic phosphate transmembrane transporter activity
AN935_RS12365	COG0573	inorganic phosphate transmembrane transporter activity
AN935_RS12370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN935_RS12375	COG0768	penicillin binding
AN935_RS12380	COG0477	Major facilitator Superfamily
AN935_RS12385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN935_RS12390	COG2839	Protein conserved in bacteria
AN935_RS12395	COG5521	maltodextrose utilization protein MalA
AN935_RS12400	COG1388	LysM domain
AN935_RS12405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AN935_RS12410	COG4709	membrane
AN935_RS12415	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AN935_RS12420	COG0735	belongs to the Fur family
AN935_RS12425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS12435	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AN935_RS12440	COG0513	Belongs to the DEAD box helicase family
AN935_RS12450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AN935_RS12455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN935_RS12460	COG2384	SAM-dependent methyltransferase
AN935_RS12465	COG2010	Cytochrome c
AN935_RS12470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AN935_RS12475	COG0358	DNA primase activity
AN935_RS12480	COG1671	Belongs to the UPF0178 family
AN935_RS12485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AN935_RS12490	COG0517	IMP dehydrogenase activity
AN935_RS12495	COG0751	glycine-tRNA ligase activity
AN935_RS12500	COG0752	glycyl-tRNA synthetase alpha subunit
AN935_RS12505	COG1381	Involved in DNA repair and RecF pathway recombination
AN935_RS12515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN935_RS12520	COG0295	cytidine deaminase activity
AN935_RS12525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AN935_RS12530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AN935_RS12535	COG1480	7TM receptor with intracellular HD hydrolase
AN935_RS12545	COG1702	phosphate starvation-inducible protein PhoH
AN935_RS12550	COG0561	phosphatase activity
AN935_RS12565	COG4864	UPF0365 protein
AN935_RS12570	COG1030	water channel activity
AN935_RS12575	COG1610	YqeY-like protein
AN935_RS12585	COG1283	sodium-dependent phosphate transmembrane transporter activity
AN935_RS12590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AN935_RS12595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN935_RS12600	COG2264	protein methyltransferase activity
AN935_RS12615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AN935_RS12620	COG1420	regulation of RNA biosynthetic process
AN935_RS12625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN935_RS12630	COG0481	GTPase activity
AN935_RS12640	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_RS12645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AN935_RS12650	COG0268	Binds directly to 16S ribosomal RNA
AN935_RS12655	COG1466	dna polymerase III delta subunit
AN935_RS12665	COG0658	competence protein
AN935_RS12665	COG2333	competence protein COMEC
AN935_RS12670	COG2131	deaminase
AN935_RS12675	COG1555	photosystem II stabilization
AN935_RS12675	COG1596	polysaccharide export
AN935_RS12680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AN935_RS12685	COG2226	methyltransferase
AN935_RS12690	COG0799	negative regulation of ribosome biogenesis
AN935_RS12695	COG1713	HD superfamily hydrolase involved in NAD metabolism
AN935_RS12700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AN935_RS12705	COG1534	Rna-binding protein
AN935_RS12710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AN935_RS12715	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AN935_RS12720	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AN935_RS12730	COG2755	lipolytic protein G-D-S-L family
AN935_RS12735	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_RS12735	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS12740	COG0398	Pfam SNARE associated Golgi protein
AN935_RS12745	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AN935_RS12755	COG3209	COG3209 Rhs family protein
AN935_RS12770	COG2814	Major facilitator Superfamily
AN935_RS12775	COG2814	Major facilitator Superfamily
AN935_RS12780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AN935_RS12785	COG1335	isochorismatase
AN935_RS12790	COG1522	sequence-specific DNA binding
AN935_RS12795	COG1522	sequence-specific DNA binding
AN935_RS12800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS12805	COG0730	response to heat
AN935_RS12810	COG0425	Belongs to the sulfur carrier protein TusA family
AN935_RS12815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS12815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_RS12825	COG0425	Belongs to the sulfur carrier protein TusA family
AN935_RS12825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_RS12835	COG2210	Belongs to the sulfur carrier protein TusA family
AN935_RS12840	COG1937	Protein conserved in bacteria
AN935_RS12860	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS12865	COG1309	transcriptional regulator
AN935_RS12870	COG2085	NADP oxidoreductase coenzyme F420-dependent
AN935_RS12875	COG1733	regulation of RNA biosynthetic process
AN935_RS12895	COG0457	Tetratricopeptide repeat
AN935_RS12905	COG5444	nuclease activity
AN935_RS12910	COG4282	regulation of fungal-type cell wall biogenesis
AN935_RS12920	COG2732	(Barnase) inhibitor
AN935_RS12935	COG4824	toxin secretion phage lysis holin
AN935_RS12960	COG0563	adenylate kinase activity
AN935_RS12980	COG0697	spore germination
AN935_RS12985	COG0583	DNA-binding transcription factor activity
AN935_RS12990	COG4124	Belongs to the glycosyl hydrolase 26 family
AN935_RS12995	COG0697	spore germination
AN935_RS13000	COG2207	Transcriptional regulator
AN935_RS13000	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS13005	COG0697	spore germination
AN935_RS13010	COG1802	Transcriptional regulator
AN935_RS13015	COG2318	DinB family
AN935_RS13020	COG0456	acetyltransferase
AN935_RS13025	COG0477	Major facilitator Superfamily
AN935_RS13030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN935_RS13040	COG0747	negative chemotaxis
AN935_RS13045	COG0601	transmembrane transport
AN935_RS13050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN935_RS13055	COG0444	Belongs to the ABC transporter superfamily
AN935_RS13060	COG4608	Belongs to the ABC transporter superfamily
AN935_RS13065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN935_RS13075	COG3443	Belongs to the bacterial solute-binding protein 9 family
AN935_RS13080	COG1595	DNA-templated transcription, initiation
AN935_RS13085	COG0667	Aldo Keto reductase
AN935_RS13090	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS13095	COG5566	PFAM Mor transcription activator
AN935_RS13100	COG0596	Alpha beta hydrolase
AN935_RS13105	COG0697	spore germination
AN935_RS13110	COG0110	maltose O-acetyltransferase activity
AN935_RS13115	COG4991	sh3 domain protein
AN935_RS13120	COG4991	sh3 domain protein
AN935_RS13130	COG5577	PFAM Coat F domain
AN935_RS13135	COG1063	alcohol dehydrogenase
AN935_RS13145	COG5577	PFAM Coat F domain
AN935_RS13155	COG0667	Aldo Keto reductase
AN935_RS13160	COG2207	Transcriptional regulator
AN935_RS13165	COG0789	Transcriptional regulator
AN935_RS13170	COG0789	Transcriptional regulator
AN935_RS13175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN935_RS13180	COG1064	alcohol dehydrogenase
AN935_RS13185	COG0693	protein deglycase activity
AN935_RS13190	COG1621	beta-fructofuranosidase activity
AN935_RS13195	COG3716	PTS system mannose fructose sorbose family IID component
AN935_RS13200	COG3715	PTS system
AN935_RS13205	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS13210	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS13215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AN935_RS13215	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AN935_RS13225	COG1113	amino acid transport
AN935_RS13230	COG1280	lysine exporter protein (LysE YggA)
AN935_RS13235	COG1378	Sugar-specific transcriptional regulator TrmB
AN935_RS13240	COG1595	DNA-templated transcription, initiation
AN935_RS13250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AN935_RS13250	COG2755	lipolytic protein G-D-S-L family
AN935_RS13260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN935_RS13260	COG2124	cytochrome p450
AN935_RS13265	COG1309	transcriptional regulator
AN935_RS13270	COG2226	methyltransferase
AN935_RS13280	COG2116	formate transmembrane transporter activity
AN935_RS13285	COG5609	conserved protein (DUF2294)
AN935_RS13290	COG3383	formate dehydrogenase (NAD+) activity
AN935_RS13295	COG2427	Protein of unknown function (DUF1641)
AN935_RS13305	COG0626	cystathionine gamma-synthase activity
AN935_RS13310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN935_RS13315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN935_RS13320	COG2226	methyltransferase
AN935_RS13335	COG0768	penicillin binding
AN935_RS13340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN935_RS13345	COG0572	uridine kinase
AN935_RS13350	COG0826	peptidase U32
AN935_RS13355	COG0826	peptidase U32
AN935_RS13360	COG4122	O-methyltransferase activity
AN935_RS13365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN935_RS13370	COG3906	Belongs to the UPF0473 family
AN935_RS13375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN935_RS13380	COG4472	Bacterial protein of unknown function (DUF965)
AN935_RS13385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AN935_RS13390	COG0628	permease
AN935_RS13395	COG1126	abc transporter atp-binding protein
AN935_RS13400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS13405	COG0765	amino acid transport
AN935_RS13410	COG0765	amino acid transport
AN935_RS13425	COG3881	PFAM PRC-barrel domain
AN935_RS13430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN935_RS13435	COG0457	Tetratricopeptide repeat
AN935_RS13440	COG0482	sulfurtransferase activity
AN935_RS13445	COG1104	cysteine desulfurase activity
AN935_RS13450	COG1959	2 iron, 2 sulfur cluster binding
AN935_RS13455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN935_RS13460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AN935_RS13470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AN935_RS13475	COG0124	histidyl-tRNA synthetase
AN935_RS13485	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_RS13485	COG4991	sh3 domain protein
AN935_RS13485	COG3103	Sh3 type 3 domain protein
AN935_RS13490	COG1490	D-aminoacyl-tRNA deacylase activity
AN935_RS13495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN935_RS13500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AN935_RS13505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN935_RS13505	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AN935_RS13510	COG5416	Lipopolysaccharide assembly protein A domain
AN935_RS13515	COG0490	domain, Protein
AN935_RS13520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN935_RS13520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN935_RS13530	COG2244	polysaccharide biosynthetic process
AN935_RS13535	COG2323	membrane
AN935_RS13545	COG1862	Preprotein translocase
AN935_RS13550	COG0343	queuine tRNA-ribosyltransferase activity
AN935_RS13555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AN935_RS13565	COG2255	four-way junction helicase activity
AN935_RS13570	COG0632	four-way junction helicase activity
AN935_RS13580	COG2814	Major facilitator Superfamily
AN935_RS13585	COG0673	inositol 2-dehydrogenase activity
AN935_RS13590	COG2112	serine threonine protein kinase
AN935_RS13610	COG1115	amino acid carrier protein
AN935_RS13615	COG0217	transcriptional regulatory protein
AN935_RS13625	COG1388	LysM domain
AN935_RS13630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AN935_RS13635	COG0157	Belongs to the NadC ModD family
AN935_RS13640	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AN935_RS13645	COG1104	cysteine desulfurase activity
AN935_RS13650	COG1827	regulation of RNA biosynthetic process
AN935_RS13655	COG0077	Prephenate dehydratase
AN935_RS13660	COG4492	Belongs to the UPF0735 family
AN935_RS13665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AN935_RS13670	COG3290	protein histidine kinase activity
AN935_RS13680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AN935_RS13685	COG2868	ribosomal protein
AN935_RS13690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AN935_RS13695	COG1994	Peptidase M50
AN935_RS13700	COG0739	heme binding
AN935_RS13705	COG2894	cell division
AN935_RS13710	COG0850	regulation of cytokinetic process
AN935_RS13715	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AN935_RS13725	COG1077	Cell shape determining protein MreB Mrl
AN935_RS13765	COG0457	Tetratricopeptide repeat
AN935_RS13770	COG5444	nuclease activity
AN935_RS13780	COG1388	LysM domain
AN935_RS13780	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS13780	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN935_RS13815	COG1705	Flagellar rod assembly protein muramidase FlgJ
AN935_RS13825	COG3953	SLT domain
AN935_RS13825	COG5280	Phage tail tape measure protein TP901
AN935_RS13995	COG2003	Belongs to the UPF0758 family
AN935_RS14000	COG0424	maF-like protein
AN935_RS14010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AN935_RS14015	COG0285	dihydrofolate synthase activity
AN935_RS14020	COG0525	valine-tRNA ligase activity
AN935_RS14030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN935_RS14035	COG1388	LysM domain
AN935_RS14040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AN935_RS14045	COG0113	porphobilinogen synthase activity
AN935_RS14050	COG1587	Uroporphyrinogen-III synthase
AN935_RS14055	COG0181	hydroxymethylbilane synthase activity
AN935_RS14060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AN935_RS14065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AN935_RS14075	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AN935_RS14080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AN935_RS14085	COG1067	ATP-dependent peptidase activity
AN935_RS14085	COG0470	DNA polymerase III
AN935_RS14090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AN935_RS14095	COG0544	peptidyl-prolyl cis-trans isomerase activity
AN935_RS14100	COG1477	protein flavinylation
AN935_RS14100	COG0457	Tetratricopeptide repeat
AN935_RS14105	COG0066	3-isopropylmalate dehydratase activity
AN935_RS14110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AN935_RS14115	COG0473	3-isopropylmalate dehydrogenase activity
AN935_RS14120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN935_RS14125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AN935_RS14130	COG0440	acetolactate synthase activity
AN935_RS14135	COG0028	Belongs to the TPP enzyme family
AN935_RS14145	COG0454	-acetyltransferase
AN935_RS14150	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AN935_RS14160	COG0622	Phosphoesterase
AN935_RS14165	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AN935_RS14170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AN935_RS14175	COG5401	PFAM Sporulation and spore germination
AN935_RS14180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN935_RS14185	COG1846	Transcriptional regulator
AN935_RS14190	COG2197	response regulator
AN935_RS14195	COG0824	Thioesterase
AN935_RS14200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN935_RS14205	COG1053	succinate dehydrogenase
AN935_RS14210	COG2009	succinate dehydrogenase
AN935_RS14220	COG1719	4-vinyl reductase, 4VR
AN935_RS14225	COG0527	aspartate kinase activity
AN935_RS14230	COG0322	excinuclease ABC activity
AN935_RS14235	COG3118	belongs to the thioredoxin family
AN935_RS14240	COG3534	alpha-L-arabinofuranosidase
AN935_RS14245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AN935_RS14250	COG2086	electron transfer activity
AN935_RS14255	COG1024	Enoyl-CoA hydratase
AN935_RS14260	COG1309	transcriptional regulator
AN935_RS14265	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_RS14270	COG3766	membrane
AN935_RS14275	COG1193	negative regulation of DNA recombination
AN935_RS14280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AN935_RS14280	COG1796	DNA polymerase
AN935_RS14285	COG1286	toxin biosynthetic process
AN935_RS14290	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AN935_RS14295	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN935_RS14300	COG0072	phenylalanine-tRNA ligase activity
AN935_RS14300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_RS14305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AN935_RS14315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN935_RS14325	COG3835	regulator
AN935_RS14330	COG0277	FAD linked oxidase domain protein
AN935_RS14335	COG0247	lactate metabolic process
AN935_RS14340	COG0346	lactoylglutathione lyase activity
AN935_RS14345	COG1966	Carbon starvation protein
AN935_RS14360	COG1695	Transcriptional regulator
AN935_RS14365	COG3534	alpha-L-arabinofuranosidase
AN935_RS14370	COG0395	ABC-type sugar transport system, permease component
AN935_RS14375	COG1175	transmembrane transport
AN935_RS14380	COG1653	transport
AN935_RS14385	COG0371	Dehydrogenase
AN935_RS14390	COG0647	UMP catabolic process
AN935_RS14395	COG0235	Class ii aldolase
AN935_RS14400	COG1069	ribulokinase activity
AN935_RS14405	COG2160	L-arabinose isomerase activity
AN935_RS14410	COG3507	Belongs to the glycosyl hydrolase 43 family
AN935_RS14415	COG1363	Peptidase, m42
AN935_RS14425	COG3326	Membrane
AN935_RS14430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AN935_RS14435	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AN935_RS14440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AN935_RS14450	COG1346	cytolysis
AN935_RS14455	COG1380	Effector of murein hydrolase LrgA
AN935_RS14460	COG3279	Response regulator of the LytR AlgR family
AN935_RS14465	COG3275	phosphorelay sensor kinase activity
AN935_RS14470	COG1011	Hydrolase
AN935_RS14475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN935_RS14485	COG0398	Pfam SNARE associated Golgi protein
AN935_RS14490	COG1484	DNA-dependent DNA replication
AN935_RS14495	COG3611	Membrane attachment protein
AN935_RS14500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AN935_RS14505	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AN935_RS14510	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN935_RS14515	COG1733	regulation of RNA biosynthetic process
AN935_RS14520	COG2814	Major facilitator Superfamily
AN935_RS14525	COG0656	L-ascorbic acid biosynthetic process
AN935_RS14530	COG0237	dephospho-CoA kinase activity
AN935_RS14545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AN935_RS14550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN935_RS14550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN935_RS14555	COG5002	protein histidine kinase activity
AN935_RS14560	COG0745	RESPONSE REGULATOR receiver
AN935_RS14565	COG0039	L-malate dehydrogenase activity
AN935_RS14570	COG0538	isocitrate dehydrogenase activity
AN935_RS14575	COG0372	Belongs to the citrate synthase family
AN935_RS14580	COG2707	UPF0756 membrane protein
AN935_RS14585	COG0628	permease
AN935_RS14590	COG3030	protein affecting phage T7 exclusion by the F plasmid
AN935_RS14595	COG0469	pyruvate kinase activity
AN935_RS14600	COG0205	6-phosphofructokinase activity
AN935_RS14605	COG0825	malonyl-CoA metabolic process
AN935_RS14610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AN935_RS14615	COG0281	malic enzyme
AN935_RS14620	COG0587	DNA-directed DNA polymerase activity
AN935_RS14640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AN935_RS14650	COG4109	DRTGG domain
AN935_RS14660	COG0730	response to heat
AN935_RS14665	COG1473	amidohydrolase
AN935_RS14670	COG0196	riboflavin kinase activity
AN935_RS14675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS14680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN935_RS14685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS14690	COG1126	abc transporter atp-binding protein
AN935_RS14695	COG0765	amino acid transport
AN935_RS14700	COG0765	amino acid transport
AN935_RS14705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS14710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS14715	COG0454	-acetyltransferase
AN935_RS14720	COG0583	DNA-binding transcription factor activity
AN935_RS14725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AN935_RS14730	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS14740	COG0165	Argininosuccinate lyase
AN935_RS14745	COG0137	argininosuccinate synthase activity
AN935_RS14750	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN935_RS14755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN935_RS14760	COG0827	DNA restriction-modification system
AN935_RS14765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AN935_RS14770	COG3874	Sporulation protein YtfJ
AN935_RS14780	COG1714	RDD family
AN935_RS14785	COG0616	signal peptide processing
AN935_RS14790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN935_RS14795	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AN935_RS14800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN935_RS14810	COG0301	tRNA thio-modification
AN935_RS14815	COG1104	cysteine desulfurase activity
AN935_RS14820	COG1114	Component of the transport system for branched-chain amino acids
AN935_RS14825	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AN935_RS14830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AN935_RS14835	COG1309	transcriptional regulator
AN935_RS14840	COG1956	GAF domain-containing protein
AN935_RS14845	COG2203	Gaf domain
AN935_RS14845	COG2199	diguanylate cyclase activity
AN935_RS14850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AN935_RS14860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN935_RS14865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN935_RS14870	COG0454	-acetyltransferase
AN935_RS14875	COG0517	IMP dehydrogenase activity
AN935_RS14880	COG0123	including yeast histone deacetylase and acetoin utilization protein
AN935_RS14885	COG1360	Flagellar Motor Protein
AN935_RS14890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AN935_RS14895	COG1609	Transcriptional regulator
AN935_RS14900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AN935_RS14900	COG1605	Chorismate mutase
AN935_RS14905	COG3118	belongs to the thioredoxin family
AN935_RS14910	COG4980	gas vesicle protein
AN935_RS14915	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AN935_RS14920	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN935_RS14925	COG1674	ftsk spoiiie
AN935_RS14930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN935_RS14935	COG4848	Belongs to the UPF0354 family
AN935_RS14940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS14950	COG1363	Peptidase, m42
AN935_RS14955	COG5584	Small secreted protein
AN935_RS14960	COG0281	malic enzyme
AN935_RS14965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS14970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN935_RS14980	COG0510	thiamine kinase activity
AN935_RS14985	COG1523	belongs to the glycosyl hydrolase 13 family
AN935_RS14990	COG1597	lipid kinase activity
AN935_RS15000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AN935_RS15005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN935_RS15010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_RS15015	COG2252	PERMEase
AN935_RS15020	COG4473	ABC transporter
AN935_RS15025	COG1131	(ABC) transporter
AN935_RS15030	COG1349	DNA-binding transcription factor activity
AN935_RS15035	COG1187	pseudouridine synthase activity
AN935_RS15040	COG2244	polysaccharide biosynthetic process
AN935_RS15045	COG2081	HI0933 family
AN935_RS15050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN935_RS15060	COG5578	integral membrane protein
AN935_RS15065	COG0673	inositol 2-dehydrogenase activity
AN935_RS15070	COG1653	transport
AN935_RS15075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AN935_RS15080	COG4209	transmembrane transport
AN935_RS15085	COG2207	Transcriptional regulator
AN935_RS15090	COG1653	transport
AN935_RS15095	COG0395	ABC-type sugar transport system, permease component
AN935_RS15100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_RS15105	COG2124	cytochrome p450
AN935_RS15110	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AN935_RS15120	COG0156	8-amino-7-oxononanoate synthase activity
AN935_RS15125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AN935_RS15130	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AN935_RS15140	COG1073	alpha beta
AN935_RS15145	COG1609	Transcriptional regulator
AN935_RS15150	COG1653	transport
AN935_RS15155	COG1175	transmembrane transport
AN935_RS15160	COG0395	ABC-type sugar transport system, permease component
AN935_RS15165	COG1486	melibiose metabolic process
AN935_RS15170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AN935_RS15175	COG0495	leucyl-tRNA aminoacylation
AN935_RS15185	COG2202	Pas domain
AN935_RS15185	COG1366	Belongs to the anti-sigma-factor antagonist family
AN935_RS15190	COG2814	Major facilitator Superfamily
AN935_RS15195	COG2433	Pfam Transposase IS66
AN935_RS15200	COG0577	efflux transmembrane transporter activity
AN935_RS15205	COG1136	(ABC) transporter
AN935_RS15210	COG2205	protein histidine kinase activity
AN935_RS15215	COG0745	RESPONSE REGULATOR receiver
AN935_RS15220	COG0577	efflux transmembrane transporter activity
AN935_RS15225	COG1136	(ABC) transporter
AN935_RS15240	COG1131	(ABC) transporter
AN935_RS15245	COG1725	Transcriptional regulator
AN935_RS15260	COG1242	4 iron, 4 sulfur cluster binding
AN935_RS15265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AN935_RS15275	COG2267	carboxylic ester hydrolase activity
AN935_RS15280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN935_RS15285	COG1113	amino acid transport
AN935_RS15290	COG0367	asparagine synthase
AN935_RS15295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AN935_RS15300	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AN935_RS15310	COG1506	peptidase
AN935_RS15315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN935_RS15320	COG1116	anion transmembrane transporter activity
AN935_RS15325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN935_RS15330	COG0494	nUDIX hydrolase
AN935_RS15335	COG4824	toxin secretion phage lysis holin
AN935_RS15340	COG0783	Belongs to the Dps family
AN935_RS15355	COG1854	S-ribosylhomocysteine lyase activity
AN935_RS15360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AN935_RS15365	COG0288	reversible hydration of carbon dioxide
AN935_RS15370	COG0254	rRNA binding
AN935_RS15375	COG1271	oxidase subunit
AN935_RS15380	COG1294	oxidase, subunit
AN935_RS15390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN935_RS15395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN935_RS15395	COG1321	iron dependent repressor
AN935_RS15400	COG1121	(ABC) transporter
AN935_RS15405	COG0803	Belongs to the bacterial solute-binding protein 9 family
AN935_RS15410	COG4948	Mandelate Racemase Muconate Lactonizing
AN935_RS15415	COG0318	PFAM AMP-dependent synthetase and ligase
AN935_RS15420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AN935_RS15425	COG0596	Alpha beta hydrolase
AN935_RS15430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AN935_RS15435	COG1169	isochorismate synthase
AN935_RS15440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN935_RS15445	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AN935_RS15450	COG0058	SHG alpha-glucan phosphorylase activity
AN935_RS15455	COG0297	glycogen (starch) synthase activity
AN935_RS15460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN935_RS15465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AN935_RS15470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AN935_RS15520	COG3859	Proton-coupled thiamine transporter YuaJ
AN935_RS15525	COG1247	-acetyltransferase
AN935_RS15530	COG2268	Band 7 protein
AN935_RS15535	COG1585	Membrane protein implicated in regulation of membrane protease activity
AN935_RS15540	COG2318	DinB family
AN935_RS15550	COG1454	alcohol dehydrogenase
AN935_RS15555	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS15560	COG1510	regulation of RNA biosynthetic process
AN935_RS15570	COG0569	domain protein
AN935_RS15575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN935_RS15580	COG4682	membrane
AN935_RS15585	COG1705	Flagellar rod assembly protein muramidase FlgJ
AN935_RS15590	COG0477	Major facilitator Superfamily
AN935_RS15595	COG5553	Cysteine dioxygenase type I
AN935_RS15605	COG1968	undecaprenyl-diphosphatase activity
AN935_RS15610	COG0628	permease
AN935_RS15615	COG0673	inositol 2-dehydrogenase activity
AN935_RS15620	COG4806	L-rhamnose isomerase
AN935_RS15625	COG3254	rhamnose metabolic process
AN935_RS15630	COG1070	Carbohydrate kinase
AN935_RS15635	COG1349	DNA-binding transcription factor activity
AN935_RS15640	COG3347	Dehydrogenase
AN935_RS15640	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS15645	COG0840	transmembrane signaling receptor activity
AN935_RS15650	COG0840	transmembrane signaling receptor activity
AN935_RS15660	COG0840	transmembrane signaling receptor activity
AN935_RS15675	COG2070	2-Nitropropane dioxygenase
AN935_RS15680	COG0432	Pfam Uncharacterised protein family UPF0047
AN935_RS15685	COG0366	Alpha amylase catalytic
AN935_RS15690	COG1253	flavin adenine dinucleotide binding
AN935_RS15695	COG2738	Putative neutral zinc metallopeptidase
AN935_RS15710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN935_RS15725	COG0166	Belongs to the GPI family
AN935_RS15730	COG1979	alcohol dehydrogenase
AN935_RS15735	COG1979	alcohol dehydrogenase
AN935_RS15740	COG2155	Conserved Protein
AN935_RS15745	COG1098	S1 RNA binding domain
AN935_RS15750	COG0436	Aminotransferase
AN935_RS15755	COG1522	sequence-specific DNA binding
AN935_RS15760	COG2267	carboxylic ester hydrolase activity
AN935_RS15770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AN935_RS15775	COG2205	protein histidine kinase activity
AN935_RS15785	COG5018	Exonuclease
AN935_RS15795	COG2814	Major facilitator Superfamily
AN935_RS15800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_RS15805	COG3011	Protein conserved in bacteria
AN935_RS15815	COG3290	protein histidine kinase activity
AN935_RS15820	COG4565	transcriptional regulatory protein
AN935_RS15825	COG1744	ABC transporter substrate-binding protein PnrA-like
AN935_RS15830	COG3845	ABC transporter
AN935_RS15835	COG4603	Belongs to the binding-protein-dependent transport system permease family
AN935_RS15840	COG1079	Belongs to the binding-protein-dependent transport system permease family
AN935_RS15845	COG3493	citrate carrier protein
AN935_RS15855	COG2111	Na H antiporter
AN935_RS15855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN935_RS15860	COG2111	Na H antiporter
AN935_RS15865	COG1006	Multisubunit Na H antiporter MnhC subunit
AN935_RS15870	COG0651	ATP synthesis coupled electron transport
AN935_RS15875	COG1863	multisubunit Na H antiporter MnhE subunit
AN935_RS15880	COG2212	antiporter activity
AN935_RS15885	COG1320	monovalent cation:proton antiporter activity
AN935_RS15890	COG2050	protein possibly involved in aromatic compounds catabolism
AN935_RS15895	COG2197	response regulator
AN935_RS15900	COG4585	Histidine kinase
AN935_RS15910	COG0142	geranyltranstransferase activity
AN935_RS15925	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AN935_RS15930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AN935_RS15935	COG1335	isochorismatase
AN935_RS15940	COG5506	Protein of unknown function (DUF1694)
AN935_RS15955	COG0628	permease
AN935_RS15970	COG1418	mRNA catabolic process
AN935_RS15975	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS15985	COG1511	domain protein
AN935_RS15990	COG1674	ftsk spoiiie
AN935_RS15990	COG0433	COG0433 Predicted ATPase
AN935_RS15995	COG4499	WXG100 protein secretion system (Wss), protein YukC
AN935_RS16000	COG5417	Belongs to the EsaB family
AN935_RS16005	COG4842	Belongs to the WXG100 family
AN935_RS16010	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AN935_RS16010	COG2508	Transcriptional regulator
AN935_RS16015	COG0686	Belongs to the AlaDH PNT family
AN935_RS16020	COG5634	Uncharacterized conserved protein (DUF2278)
AN935_RS16025	COG3251	PFAM MbtH domain protein
AN935_RS16030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS16035	COG3433	isochorismatase activity
AN935_RS16035	COG1535	isochorismatase
AN935_RS16040	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN935_RS16045	COG1169	isochorismate synthase
AN935_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS16055	COG2819	hydrolase of the alpha beta superfamily
AN935_RS16060	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AN935_RS16065	COG1268	BioY protein
AN935_RS16070	COG2056	Na+-H+ antiporter family
AN935_RS16075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AN935_RS16080	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AN935_RS16085	COG3584	3D domain protein
AN935_RS16100	COG1252	NADH dehydrogenase
AN935_RS16105	COG0492	ferredoxin-NADP+ reductase activity
AN935_RS16115	COG0516	GMP reductase activity
AN935_RS16120	COG2808	Putative FMN-binding domain
AN935_RS16125	COG0456	acetyltransferase
AN935_RS16130	COG0316	Belongs to the HesB IscA family
AN935_RS16135	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AN935_RS16140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN935_RS16145	COG4844	belongs to the
AN935_RS16150	COG1252	NADH dehydrogenase
AN935_RS16155	COG4837	Protein of unknown function (DUF1462)
AN935_RS16160	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AN935_RS16165	COG4946	Tricorn protease homolog
AN935_RS16165	COG1506	peptidase
AN935_RS16165	COG0823	Involved in the tonB-independent uptake of proteins
AN935_RS16170	COG0083	homoserine kinase activity
AN935_RS16175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AN935_RS16180	COG0460	homoserine dehydrogenase
AN935_RS16185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN935_RS16190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN935_RS16195	COG0647	UMP catabolic process
AN935_RS16200	COG2445	Protein of unknown function DUF86
AN935_RS16205	COG4470	Protein conserved in bacteria
AN935_RS16215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN935_RS16220	COG0739	heme binding
AN935_RS16230	COG3377	Domain of unknown function (DUF1805)
AN935_RS16235	COG0737	Belongs to the 5'-nucleotidase family
AN935_RS16240	COG0730	response to heat
AN935_RS16245	COG1801	Protein of unknown function DUF72
AN935_RS16255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AN935_RS16260	COG2508	Transcriptional regulator
AN935_RS16265	COG2233	PERMEase
AN935_RS16270	COG2233	PERMEase
AN935_RS16275	COG3648	Uricase
AN935_RS16275	COG3195	allantoin biosynthetic process
AN935_RS16280	COG2351	hydroxyisourate hydrolase activity
AN935_RS16295	COG2080	2 iron, 2 sulfur cluster binding
AN935_RS16300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN935_RS16305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AN935_RS16310	COG2068	MobA-Related Protein
AN935_RS16315	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AN935_RS16320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN935_RS16325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AN935_RS16335	COG2356	endonuclease I
AN935_RS16340	COG3842	ATPase activity
AN935_RS16345	COG2188	Transcriptional regulator
AN935_RS16350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_RS16355	COG0395	ABC-type sugar transport system, permease component
AN935_RS16360	COG1175	transmembrane transport
AN935_RS16365	COG1653	transport
AN935_RS16370	COG2222	sugar isomerase
AN935_RS16375	COG0322	excinuclease ABC activity
AN935_RS16380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN935_RS16400	COG0640	Transcriptional regulator
AN935_RS16405	COG0719	Fe-S assembly protein
AN935_RS16410	COG0822	iron-sulfur transferase activity
AN935_RS16415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN935_RS16420	COG0719	Fe-S assembly protein
AN935_RS16425	COG0396	ATPase activity
AN935_RS16435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN935_RS16440	COG1464	Belongs to the NlpA lipoprotein family
AN935_RS16445	COG2011	ABC-type metal ion transport system permease component
AN935_RS16450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN935_RS16460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AN935_RS16465	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AN935_RS16475	COG0509	glycine decarboxylation via glycine cleavage system
AN935_RS16480	COG1393	Belongs to the ArsC family
AN935_RS16485	COG1960	acyl-CoA dehydrogenase activity
AN935_RS16490	COG0183	Belongs to the thiolase family
AN935_RS16495	COG1024	Enoyl-CoA hydratase
AN935_RS16495	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN935_RS16505	COG0506	proline dehydrogenase activity
AN935_RS16515	COG5577	PFAM Coat F domain
AN935_RS16520	COG1846	Transcriptional regulator
AN935_RS16525	COG0477	Major facilitator Superfamily
AN935_RS16530	COG1942	4-Oxalocrotonate Tautomerase
AN935_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS16540	COG0583	DNA-binding transcription factor activity
AN935_RS16550	COG1120	ATPase activity
AN935_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS16570	COG0783	Belongs to the Dps family
AN935_RS16575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_RS16580	COG0745	RESPONSE REGULATOR receiver
AN935_RS16585	COG2205	protein histidine kinase activity
AN935_RS16585	COG2770	Histidine kinase
AN935_RS16595	COG1309	transcriptional regulator
AN935_RS16600	COG0114	fumarate hydratase activity
AN935_RS16610	COG0697	spore germination
AN935_RS16615	COG0814	amino acid
AN935_RS16625	COG2197	response regulator
AN935_RS16630	COG4585	Histidine kinase
AN935_RS16635	COG4758	membrane
AN935_RS16640	COG3595	metallopeptidase activity
AN935_RS16645	COG1842	Phage shock protein A
AN935_RS16650	COG4758	membrane
AN935_RS16655	COG2814	Major facilitator Superfamily
AN935_RS16660	COG2096	Adenosyltransferase
AN935_RS16665	COG1120	ATPase activity
AN935_RS16670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS16675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_RS16680	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS16685	COG3386	PFAM SMP-30 Gluconolaconase
AN935_RS16690	COG2205	protein histidine kinase activity
AN935_RS16695	COG0745	RESPONSE REGULATOR receiver
AN935_RS16705	COG1191	sigma factor activity
AN935_RS16715	COG2140	Oxalate decarboxylase
AN935_RS16725	COG0577	efflux transmembrane transporter activity
AN935_RS16730	COG1136	(ABC) transporter
AN935_RS16735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN935_RS16740	COG1120	ATPase activity
AN935_RS16745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS16750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN935_RS16755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_RS16760	COG0640	Transcriptional regulator
AN935_RS16775	COG0531	amino acid
AN935_RS16785	COG1988	membrane-bound metal-dependent
AN935_RS16790	COG1368	sulfuric ester hydrolase activity
AN935_RS16795	COG1910	domain protein
AN935_RS16800	COG0725	ABC transporter, periplasmic molybdate-binding protein
AN935_RS16805	COG4149	molybdate abc transporter
AN935_RS16810	COG0656	L-ascorbic acid biosynthetic process
AN935_RS16820	COG0025	NhaP-type Na H and K H
AN935_RS16825	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN935_RS16830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN935_RS16835	COG3973	AAA domain
AN935_RS16840	COG2860	membrane
AN935_RS16845	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AN935_RS16850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN935_RS16855	COG2217	Heavy metal translocating P-type atpase
AN935_RS16860	COG2217	Heavy metal translocating P-type atpase
AN935_RS16865	COG2608	mercury ion transmembrane transporter activity
AN935_RS16870	COG1937	Protein conserved in bacteria
AN935_RS16875	COG0673	inositol 2-dehydrogenase activity
AN935_RS16880	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN935_RS16885	COG1289	transmembrane transporter activity
AN935_RS16900	COG2076	Multidrug Resistance protein
AN935_RS16905	COG1309	transcriptional regulator
AN935_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS16930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AN935_RS16935	COG0557	exoribonuclease II activity
AN935_RS16940	COG1647	Serine aminopeptidase, S33
AN935_RS16945	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AN935_RS16950	COG0596	Alpha beta hydrolase
AN935_RS16955	COG1476	TRANSCRIPTIONal
AN935_RS16960	COG1396	sequence-specific DNA binding
AN935_RS16965	COG1396	sequence-specific DNA binding
AN935_RS16970	COG1733	regulation of RNA biosynthetic process
AN935_RS16975	COG0840	transmembrane signaling receptor activity
AN935_RS16980	COG1174	glycine betaine transport
AN935_RS16985	COG1732	Glycine betaine
AN935_RS16990	COG1174	glycine betaine transport
AN935_RS16995	COG0517	IMP dehydrogenase activity
AN935_RS16995	COG1125	glycine betaine transport
AN935_RS17000	COG1510	regulation of RNA biosynthetic process
AN935_RS17005	COG1174	glycine betaine transport
AN935_RS17010	COG1732	Glycine betaine
AN935_RS17015	COG1174	glycine betaine transport
AN935_RS17020	COG0517	IMP dehydrogenase activity
AN935_RS17020	COG1125	glycine betaine transport
AN935_RS17025	COG1510	regulation of RNA biosynthetic process
AN935_RS17035	COG3064	Membrane
AN935_RS17040	COG4640	response to antibiotic
AN935_RS17045	COG0456	acetyltransferase
AN935_RS17055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN935_RS17065	COG0126	phosphoglycerate kinase activity
AN935_RS17075	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN935_RS17080	COG2390	Transcriptional regulator
AN935_RS17085	COG2814	Major facilitator Superfamily
AN935_RS17090	COG1609	Transcriptional regulator
AN935_RS17095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS17100	COG0583	DNA-binding transcription factor activity
AN935_RS17105	COG0697	spore germination
AN935_RS17110	COG1113	amino acid transport
AN935_RS17115	COG3858	chitin binding
AN935_RS17120	COG1556	Lactate utilization protein
AN935_RS17125	COG1139	Iron-sulfur cluster binding protein
AN935_RS17130	COG0247	lactate metabolic process
AN935_RS17135	COG2197	response regulator
AN935_RS17140	COG4585	Histidine kinase
AN935_RS17145	COG0842	Transport permease protein
AN935_RS17150	COG1131	(ABC) transporter
AN935_RS17155	COG0596	Alpha beta hydrolase
AN935_RS17160	COG2208	phosphoserine phosphatase activity
AN935_RS17165	COG3867	Arabinogalactan endo-beta-1,4-galactanase
AN935_RS17170	COG1874	Beta-galactosidase
AN935_RS17175	COG3833	ABC-type maltose transport systems, permease component
AN935_RS17180	COG1175	transmembrane transport
AN935_RS17185	COG2182	Extracellular solute-binding protein
AN935_RS17190	COG1609	Transcriptional regulator
AN935_RS17195	COG2186	Transcriptional regulator
AN935_RS17200	COG1620	l-lactate permease
AN935_RS17205	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AN935_RS17215	COG5039	Polysaccharide pyruvyl transferase
AN935_RS17220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_RS17225	COG0110	maltose O-acetyltransferase activity
AN935_RS17230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AN935_RS17235	COG2244	polysaccharide biosynthetic process
AN935_RS17240	COG1216	Glycosyl transferase, family 2
AN935_RS17245	COG5039	Polysaccharide pyruvyl transferase
AN935_RS17250	COG1216	Glycosyl transferase, family 2
AN935_RS17260	COG0438	transferase activity, transferring glycosyl groups
AN935_RS17265	COG1215	transferase activity, transferring glycosyl groups
AN935_RS17270	COG0438	transferase activity, transferring glycosyl groups
AN935_RS17275	COG1086	Polysaccharide biosynthesis protein
AN935_RS17280	COG0489	protein tyrosine kinase activity
AN935_RS17285	COG3944	biosynthesis protein
AN935_RS17290	COG1396	sequence-specific DNA binding
AN935_RS17295	COG2272	Belongs to the type-B carboxylesterase lipase family
AN935_RS17305	COG3479	Phenolic acid decarboxylase
AN935_RS17315	COG1794	racemase activity, acting on amino acids and derivatives
AN935_RS17320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN935_RS17330	COG1621	beta-fructofuranosidase activity
AN935_RS17335	COG1621	beta-fructofuranosidase activity
AN935_RS17340	COG0531	amino acid
AN935_RS17345	COG1309	transcriptional regulator
AN935_RS17350	COG2076	Multidrug Resistance protein
AN935_RS17355	COG2076	Multidrug Resistance protein
AN935_RS17375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN935_RS17380	COG0366	Alpha amylase catalytic
AN935_RS17385	COG1554	hydrolase, family 65, central catalytic
AN935_RS17395	COG3833	ABC-type maltose transport systems, permease component
AN935_RS17400	COG1175	transmembrane transport
AN935_RS17405	COG2182	Extracellular solute-binding protein
AN935_RS17410	COG0366	Alpha amylase catalytic
AN935_RS17415	COG1609	Transcriptional regulator
AN935_RS17420	COG1611	Belongs to the LOG family
AN935_RS17425	COG1694	Mazg nucleotide pyrophosphohydrolase
AN935_RS17435	COG0288	reversible hydration of carbon dioxide
AN935_RS17440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AN935_RS17445	COG0577	efflux transmembrane transporter activity
AN935_RS17450	COG1136	(ABC) transporter
AN935_RS17455	COG5002	protein histidine kinase activity
AN935_RS17460	COG0745	RESPONSE REGULATOR receiver
AN935_RS17470	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AN935_RS17475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS17480	COG1481	regulation of sporulation
AN935_RS17485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AN935_RS17490	COG1660	Displays ATPase and GTPase activities
AN935_RS17495	COG1051	belongs to the nudix hydrolase family
AN935_RS17500	COG0492	ferredoxin-NADP+ reductase activity
AN935_RS17505	COG0791	NLP P60 protein
AN935_RS17505	COG3883	PFAM NLP P60 protein
AN935_RS17510	COG0457	Tetratricopeptide repeat
AN935_RS17515	COG1132	(ABC) transporter
AN935_RS17535	COG0140	phosphoribosyl-ATP diphosphatase activity
AN935_RS17535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AN935_RS17540	COG0107	imidazoleglycerol-phosphate synthase activity
AN935_RS17545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AN935_RS17550	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AN935_RS17555	COG0131	Imidazoleglycerol-phosphate dehydratase
AN935_RS17560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AN935_RS17565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN935_RS17570	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AN935_RS17575	COG4990	cell redox homeostasis
AN935_RS17580	COG5297	Belongs to the glycosyl hydrolase family 6
AN935_RS17585	COG0110	maltose O-acetyltransferase activity
AN935_RS17590	COG0546	phosphoglycolate phosphatase activity
AN935_RS17595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AN935_RS17600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AN935_RS17605	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AN935_RS17610	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AN935_RS17615	COG0363	glucosamine-6-phosphate deaminase activity
AN935_RS17620	COG2188	Transcriptional regulator
AN935_RS17625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN935_RS17630	COG1846	Transcriptional regulator
AN935_RS17635	COG2814	Major facilitator Superfamily
AN935_RS17640	COG1950	PFAM Membrane protein of
AN935_RS17645	COG1983	PspC domain protein
AN935_RS17650	COG3595	metallopeptidase activity
AN935_RS17665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN935_RS17670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN935_RS17675	COG0556	nucleotide-excision repair
AN935_RS17680	COG4897	Protein conserved in bacteria
AN935_RS17690	COG0574	Belongs to the PEP-utilizing enzyme family
AN935_RS17690	COG3848	Pyruvate phosphate dikinase
AN935_RS17695	COG1309	transcriptional regulator
AN935_RS17700	COG2814	Major facilitator Superfamily
AN935_RS17705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_RS17715	COG0793	Belongs to the peptidase S41A family
AN935_RS17715	COG3409	Peptidoglycan-binding domain 1 protein
AN935_RS17720	COG2177	Part of the ABC transporter FtsEX involved in
AN935_RS17725	COG2884	Cell division ATP-binding protein ftsE
AN935_RS17730	COG2010	Cytochrome c
AN935_RS17735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS17745	COG0653	protein targeting
AN935_RS17750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AN935_RS17765	COG1516	flagellar protein fliS
AN935_RS17770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AN935_RS17775	COG1334	flagellar protein FlaG
AN935_RS17780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN935_RS17785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AN935_RS17790	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AN935_RS17800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AN935_RS17805	COG1256	bacterial-type flagellum assembly
AN935_RS17805	COG4786	Flagellar basal body rod
AN935_RS17810	COG3418	PFAM FlgN family protein
AN935_RS17815	COG2747	anti-sigma28 factor FlgM
AN935_RS17825	COG1040	competence protein
AN935_RS17835	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AN935_RS17840	COG1307	EDD domain protein, DegV family
AN935_RS17845	COG2197	response regulator
AN935_RS17850	COG4585	Histidine kinase
AN935_RS17855	COG1739	Uncharacterized protein family UPF0029
AN935_RS17860	COG1316	TRANSCRIPTIONal
AN935_RS17865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN935_RS17870	COG0438	transferase activity, transferring glycosyl groups
AN935_RS17875	COG1215	transferase activity, transferring glycosyl groups
AN935_RS17880	COG3206	protein involved in exopolysaccharide biosynthesis
AN935_RS17885	COG3307	-O-antigen
AN935_RS17890	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AN935_RS17895	COG0438	transferase activity, transferring glycosyl groups
AN935_RS17895	COG0297	glycogen (starch) synthase activity
AN935_RS17900	COG2244	polysaccharide biosynthetic process
AN935_RS17915	COG0860	N-Acetylmuramoyl-L-alanine amidase
AN935_RS17915	COG2247	cell wall binding repeat
AN935_RS17920	COG2247	cell wall binding repeat
AN935_RS17920	COG2385	sporulation resulting in formation of a cellular spore
AN935_RS17930	COG1316	TRANSCRIPTIONal
AN935_RS17935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN935_RS17955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN935_RS17960	COG1134	teichoic acid transport
AN935_RS17965	COG1682	transport, permease protein
AN935_RS17970	COG1215	transferase activity, transferring glycosyl groups
AN935_RS17980	COG1181	Belongs to the D-alanine--D-alanine ligase family
AN935_RS17985	COG0463	Glycosyl transferase, family 2
AN935_RS17985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AN935_RS17995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AN935_RS18005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AN935_RS18040	COG4193	domain, Protein
AN935_RS18045	COG1482	cell wall glycoprotein biosynthetic process
AN935_RS18055	COG0697	spore germination
AN935_RS18060	COG0814	amino acid
AN935_RS18070	COG2814	Major facilitator Superfamily
AN935_RS18075	COG1316	TRANSCRIPTIONal
AN935_RS18080	COG0561	phosphatase activity
AN935_RS18085	COG0791	NLP P60 protein
AN935_RS18095	COG2843	Capsule synthesis protein
AN935_RS18105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AN935_RS18110	COG1609	Transcriptional regulator
AN935_RS18115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_RS18120	COG1869	D-ribose catabolic process
AN935_RS18125	COG1129	ABC transporter
AN935_RS18130	COG1172	Belongs to the binding-protein-dependent transport system permease family
AN935_RS18135	COG1879	ABC-type sugar transport system periplasmic component
AN935_RS18140	COG3103	Sh3 type 3 domain protein
AN935_RS18150	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN935_RS18155	COG3527	Alpha-acetolactate decarboxylase
AN935_RS18160	COG0028	Belongs to the TPP enzyme family
AN935_RS18165	COG0583	DNA-binding transcription factor activity
AN935_RS18170	COG5337	Spore coat protein CotH
AN935_RS18180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN935_RS18190	COG0405	Gamma-glutamyltransferase
AN935_RS18195	COG1522	sequence-specific DNA binding
AN935_RS18200	COG2059	Chromate
AN935_RS18205	COG2059	Chromate
AN935_RS18215	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN935_RS18220	COG0583	DNA-binding transcription factor activity
AN935_RS18235	COG5444	nuclease activity
AN935_RS18250	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AN935_RS18255	COG4464	protein tyrosine phosphatase activity
AN935_RS18260	COG0489	protein tyrosine kinase activity
AN935_RS18265	COG3944	biosynthesis protein
AN935_RS18275	COG4715	Zinc finger, swim domain protein
AN935_RS18280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AN935_RS18285	COG0561	phosphatase activity
AN935_RS18290	COG1349	DNA-binding transcription factor activity
AN935_RS18295	COG0629	single-stranded DNA binding
AN935_RS18310	COG2602	Beta-lactamase
AN935_RS18315	COG3764	Sortase (surface protein transpeptidase)
AN935_RS18325	COG3279	Response regulator of the LytR AlgR family
AN935_RS18330	COG2972	Histidine kinase
AN935_RS18330	COG0745	RESPONSE REGULATOR receiver
AN935_RS18335	COG1970	mechanosensitive ion channel activity
AN935_RS18340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AN935_RS18345	COG0457	Tetratricopeptide repeat
AN935_RS18350	COG4786	Flagellar basal body rod
AN935_RS18355	COG4786	Flagellar basal body rod
AN935_RS18360	COG1077	Cell shape determining protein MreB Mrl
AN935_RS18365	COG1609	Transcriptional regulator
AN935_RS18370	COG1846	Transcriptional regulator
AN935_RS18375	COG2814	Major facilitator Superfamily
AN935_RS18380	COG3420	alginic acid biosynthetic process
AN935_RS18385	COG1953	Uracil, thiamine, allantoin
AN935_RS18390	COG0477	Major facilitator Superfamily
AN935_RS18395	COG1335	isochorismatase
AN935_RS18405	COG0004	ammonium transporteR
AN935_RS18410	COG0347	Belongs to the P(II) protein family
AN935_RS18415	COG0671	phosphoesterase, PA-phosphatase related
AN935_RS18425	COG0739	heme binding
AN935_RS18430	COG1247	-acetyltransferase
AN935_RS18440	COG1086	Polysaccharide biosynthesis protein
AN935_RS18445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_RS18450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_RS18455	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AN935_RS18470	COG2089	acid synthase
AN935_RS18480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN935_RS18485	COG0789	Transcriptional regulator
AN935_RS18495	COG2910	NAD(P)H-binding
AN935_RS18500	COG1959	2 iron, 2 sulfur cluster binding
AN935_RS18505	COG0804	urea catabolic process
AN935_RS18510	COG0832	Belongs to the urease beta subunit family
AN935_RS18515	COG0831	urea catabolic process
AN935_RS18545	COG3237	CsbD-like
AN935_RS18550	COG1994	Peptidase M50
AN935_RS18555	COG0457	Tetratricopeptide repeat
AN935_RS18560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN935_RS18565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AN935_RS18575	COG2304	oxidoreductase activity
AN935_RS18580	COG2304	oxidoreductase activity
AN935_RS18585	COG2385	sporulation resulting in formation of a cellular spore
AN935_RS18590	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN935_RS18600	COG4836	Membrane
AN935_RS18620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AN935_RS18625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AN935_RS18630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AN935_RS18635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AN935_RS18640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AN935_RS18655	COG0356	it plays a direct role in the translocation of protons across the membrane
AN935_RS18665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AN935_RS18670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AN935_RS18675	COG4475	Protein of unknown function (DUF436)
AN935_RS18680	COG0698	ribose 5-phosphate isomerase
AN935_RS18685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN935_RS18690	COG1971	Probably functions as a manganese efflux pump
AN935_RS18695	COG0009	L-threonylcarbamoyladenylate synthase
AN935_RS18700	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AN935_RS18720	COG2890	protein-(glutamine-N5) methyltransferase activity
AN935_RS18725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AN935_RS18730	COG0346	lactoylglutathione lyase activity
AN935_RS18735	COG0789	Transcriptional regulator
AN935_RS18740	COG0679	Auxin Efflux Carrier
AN935_RS18745	COG0281	malic enzyme
AN935_RS18750	COG1435	thymidine kinase activity
AN935_RS18760	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AN935_RS18770	COG1494	fructose-1,6-bisphosphatase
AN935_RS18775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN935_RS18780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN935_RS18785	COG0191	fructose-bisphosphate aldolase activity
AN935_RS18790	COG2204	response regulator
AN935_RS18795	COG4821	SIS domain
AN935_RS18800	COG0504	CTP synthase activity
AN935_RS18805	COG3343	RNA polymerase activity
AN935_RS18810	COG1960	acyl-CoA dehydrogenase activity
AN935_RS18815	COG0247	lactate metabolic process
AN935_RS18815	COG2181	nitrate reductase activity
AN935_RS18820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN935_RS18825	COG4294	response to UV
AN935_RS18835	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AN935_RS18840	COG1132	(ABC) transporter
AN935_RS18845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN935_RS18855	COG2181	nitrate reductase activity
AN935_RS18860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AN935_RS18865	COG1140	nitrate reductase beta subunit
AN935_RS18870	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AN935_RS18875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN935_RS18885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN935_RS18890	COG2223	nitrite transmembrane transporter activity
AN935_RS18895	COG0018	arginyl-trna synthetase
AN935_RS18900	COG4506	Protein conserved in bacteria
AN935_RS18910	COG0535	radical SAM domain protein
AN935_RS18920	COG1131	(ABC) transporter
AN935_RS18930	COG0612	Peptidase, M16
AN935_RS18945	COG3391	amine dehydrogenase activity
AN935_RS18950	COG3391	amine dehydrogenase activity
AN935_RS18960	COG0457	Tetratricopeptide repeat
AN935_RS18975	COG0010	Belongs to the arginase family
AN935_RS18980	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AN935_RS18985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN935_RS18995	COG1994	Peptidase M50
AN935_RS19000	COG1942	4-Oxalocrotonate Tautomerase
AN935_RS19005	COG1846	Transcriptional regulator
AN935_RS19010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AN935_RS19025	COG1959	2 iron, 2 sulfur cluster binding
AN935_RS19030	COG3465	dGTPase activity
AN935_RS19035	COG1078	dGTPase activity
AN935_RS19040	COG4844	belongs to the
AN935_RS19050	COG0697	spore germination
AN935_RS19060	COG0095	Lipoate-protein ligase
AN935_RS19065	COG0583	DNA-binding transcription factor activity
AN935_RS19070	COG0280	phosphate acetyltransferase
AN935_RS19075	COG3253	May function as heme-dependent peroxidase
AN935_RS19080	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS19085	COG0436	Aminotransferase
AN935_RS19090	COG2814	Major facilitator Superfamily
AN935_RS19095	COG0151	Belongs to the GarS family
AN935_RS19100	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS19105	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS19110	COG0077	Prephenate dehydratase
AN935_RS19115	COG2814	Major facilitator Superfamily
AN935_RS19120	COG0833	amino acid
AN935_RS19125	COG4187	Peptidase family M20/M25/M40
AN935_RS19130	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS19135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN935_RS19145	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AN935_RS19150	COG1091	dTDP-4-dehydrorhamnose reductase activity
AN935_RS19155	COG1088	dTDP-glucose 4,6-dehydratase activity
AN935_RS19160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AN935_RS19165	COG0456	acetyltransferase
AN935_RS19170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_RS19170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN935_RS19175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AN935_RS19180	COG0463	Glycosyl transferase, family 2
AN935_RS19195	COG2363	Small membrane protein
AN935_RS19200	COG2233	PERMEase
AN935_RS19210	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS19215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AN935_RS19220	COG1216	Glycosyl transferase, family 2
AN935_RS19225	COG0351	phosphomethylpyrimidine kinase
AN935_RS19235	COG1621	beta-fructofuranosidase activity
AN935_RS19240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS19240	COG1263	PTS System
AN935_RS19245	COG2116	formate transmembrane transporter activity
AN935_RS19250	COG3711	transcriptional antiterminator
AN935_RS19260	COG1404	Belongs to the peptidase S8 family
AN935_RS19265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS19270	COG0778	Nitroreductase
AN935_RS19275	COG0772	Belongs to the SEDS family
AN935_RS19300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN935_RS19305	COG2261	transglycosylase associated protein
AN935_RS19310	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AN935_RS19315	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AN935_RS19320	COG2246	polysaccharide biosynthetic process
AN935_RS19325	COG1309	transcriptional regulator
AN935_RS19335	COG3162	membrane
AN935_RS19340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN935_RS19345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AN935_RS19350	COG2837	iron assimilation
AN935_RS19355	COG2822	iron ion transport
AN935_RS19360	COG0672	)-iron permease
AN935_RS19365	COG0352	thiamine-phosphate diphosphorylase activity
AN935_RS19370	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AN935_RS19375	COG0583	DNA-binding transcription factor activity
AN935_RS19380	COG1380	Effector of murein hydrolase LrgA
AN935_RS19385	COG1346	cytolysis
AN935_RS19390	COG2814	Major facilitator Superfamily
AN935_RS19395	COG4895	conserved protein (DUF2196)
AN935_RS19400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AN935_RS19405	COG0346	lactoylglutathione lyase activity
AN935_RS19415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_RS19420	COG1404	Belongs to the peptidase S8 family
AN935_RS19425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS19425	COG1263	PTS System
AN935_RS19430	COG3711	transcriptional antiterminator
AN935_RS19435	COG1442	glycosyl transferase family 8
AN935_RS19440	COG5522	Integral membrane protein (intg_mem_TP0381)
AN935_RS19445	COG1846	Transcriptional regulator
AN935_RS19455	COG2234	aminopeptidase activity
AN935_RS19470	COG2814	Major facilitator Superfamily
AN935_RS19475	COG2357	RelA SpoT domain protein
AN935_RS19480	COG1575	Belongs to the MenA family. Type 1 subfamily
AN935_RS19495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS19500	COG1696	Membrane protein involved in D-alanine export
AN935_RS19505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN935_RS19510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AN935_RS19515	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AN935_RS19520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN935_RS19525	COG1486	melibiose metabolic process
AN935_RS19530	COG1447	Phosphotransferase system cellobiose-specific component IIA
AN935_RS19535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_RS19540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AN935_RS19545	COG3711	transcriptional antiterminator
AN935_RS19545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN935_RS19555	COG2094	Belongs to the DNA glycosylase MPG family
AN935_RS19560	COG0753	catalase activity
AN935_RS19565	COG2814	Major facilitator Superfamily
AN935_RS19570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AN935_RS19575	COG1131	(ABC) transporter
AN935_RS19595	COG1595	DNA-templated transcription, initiation
AN935_RS19600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN935_RS19605	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN935_RS19610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AN935_RS19615	COG4988	ABC transporter
AN935_RS19620	COG1294	oxidase, subunit
AN935_RS19625	COG1271	oxidase subunit
AN935_RS19630	COG3493	citrate carrier protein
AN935_RS19640	COG0726	polysaccharide deacetylase
AN935_RS19650	COG3842	ATPase activity
AN935_RS19655	COG2508	Transcriptional regulator
AN935_RS19660	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS19665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AN935_RS19675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN935_RS19685	COG4585	Histidine kinase
AN935_RS19690	COG2197	response regulator
AN935_RS19695	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN935_RS19710	COG4894	glucomannan catabolic process
AN935_RS19720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AN935_RS19725	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS19730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN935_RS19735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN935_RS19740	COG2610	gluconate transmembrane transporter activity
AN935_RS19750	COG0500	methyltransferase
AN935_RS19755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN935_RS19770	COG0753	catalase activity
AN935_RS19770	COG0693	protein deglycase activity
AN935_RS19775	COG2851	Citrate transporter
AN935_RS19780	COG2273	Hydrolase Family 16
AN935_RS19790	COG2723	6-phospho-beta-galactosidase activity
AN935_RS19795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS19795	COG1263	PTS System
AN935_RS19795	COG2190	(PTS) system
AN935_RS19800	COG3711	transcriptional antiterminator
AN935_RS19810	COG2270	Major facilitator Superfamily
AN935_RS19815	COG0513	Belongs to the DEAD box helicase family
AN935_RS19820	COG3401	FG-GAP repeat protein
AN935_RS19820	COG2755	lipolytic protein G-D-S-L family
AN935_RS19905	COG0697	spore germination
AN935_RS19915	COG0861	Integral membrane protein TerC family
AN935_RS19920	COG0589	response to stress
AN935_RS19925	COG2723	6-phospho-beta-galactosidase activity
AN935_RS19930	COG1263	PTS System
AN935_RS19930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS19930	COG2190	(PTS) system
AN935_RS19970	COG5444	nuclease activity
AN935_RS20005	COG3507	Belongs to the glycosyl hydrolase 43 family
AN935_RS20020	COG2986	histidine ammonia-lyase
AN935_RS20025	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AN935_RS20030	COG1228	amidohydrolase
AN935_RS20035	COG0010	Belongs to the arginase family
AN935_RS20040	COG0833	amino acid
AN935_RS20045	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AN935_RS20050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AN935_RS20055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AN935_RS20060	COG2390	Transcriptional regulator
AN935_RS20070	COG3192	ethanolamine utilization protein
AN935_RS20075	COG2079	MmgE PrpD family protein
AN935_RS20080	COG1473	amidohydrolase
AN935_RS20085	COG1126	abc transporter atp-binding protein
AN935_RS20090	COG0765	amino acid transport
AN935_RS20095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN935_RS20100	COG0456	acetyltransferase
AN935_RS20105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN935_RS20110	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AN935_RS20115	COG0561	phosphatase activity
AN935_RS20145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AN935_RS20150	COG5294	Protein conserved in bacteria
AN935_RS20155	COG0577	efflux transmembrane transporter activity
AN935_RS20160	COG1136	(ABC) transporter
AN935_RS20165	COG2205	protein histidine kinase activity
AN935_RS20170	COG0745	RESPONSE REGULATOR receiver
AN935_RS20175	COG0191	fructose-bisphosphate aldolase activity
AN935_RS20180	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS20185	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS20190	COG0673	inositol 2-dehydrogenase activity
AN935_RS20195	COG2814	Major facilitator Superfamily
AN935_RS20200	COG1082	Xylose isomerase domain protein TIM barrel
AN935_RS20205	COG3962	Belongs to the TPP enzyme family
AN935_RS20210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN935_RS20220	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS20225	COG1349	DNA-binding transcription factor activity
AN935_RS20230	COG0667	Aldo Keto reductase
AN935_RS20245	COG2271	Major facilitator Superfamily
AN935_RS20265	COG2814	Major facilitator Superfamily
AN935_RS20270	COG0326	Molecular chaperone. Has ATPase activity
AN935_RS20280	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS20285	COG1309	transcriptional regulator
AN935_RS20290	COG1012	belongs to the aldehyde dehydrogenase family
AN935_RS20300	COG0667	Aldo Keto reductase
AN935_RS20305	COG0789	Transcriptional regulator
AN935_RS20310	COG1714	RDD family
AN935_RS20315	COG2311	Membrane
AN935_RS20320	COG1917	Cupin 2, conserved barrel domain protein
AN935_RS20325	COG1309	transcriptional regulator
AN935_RS20330	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS20335	COG1846	Transcriptional regulator
AN935_RS20340	COG1380	Effector of murein hydrolase LrgA
AN935_RS20345	COG1346	cytolysis
AN935_RS20365	COG5039	Polysaccharide pyruvyl transferase
AN935_RS20370	COG1929	Belongs to the glycerate kinase type-1 family
AN935_RS20375	COG1802	Transcriptional regulator
AN935_RS20380	COG1070	Carbohydrate kinase
AN935_RS20385	COG2610	gluconate transmembrane transporter activity
AN935_RS20390	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AN935_RS20395	COG0450	alkyl hydroperoxide reductase
AN935_RS20400	COG3634	alkyl hydroperoxide reductase activity
AN935_RS20410	COG2723	6-phospho-beta-galactosidase activity
AN935_RS20415	COG1263	PTS System
AN935_RS20415	COG2190	(PTS) system
AN935_RS20415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AN935_RS20420	COG2188	Transcriptional regulator
AN935_RS20425	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AN935_RS20440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AN935_RS20450	COG1063	alcohol dehydrogenase
AN935_RS20470	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AN935_RS20480	COG0457	Tetratricopeptide repeat
AN935_RS20490	COG0010	Belongs to the arginase family
AN935_RS20495	COG0833	amino acid
AN935_RS20500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN935_RS20505	COG3829	transcription factor binding
AN935_RS20510	COG5002	protein histidine kinase activity
AN935_RS20515	COG0745	RESPONSE REGULATOR receiver
AN935_RS20535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN935_RS20540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AN935_RS20545	COG4853	Protein conserved in bacteria
AN935_RS20550	COG4863	YycH protein
AN935_RS20555	COG5002	protein histidine kinase activity
AN935_RS20560	COG0745	RESPONSE REGULATOR receiver
AN935_RS20590	COG0346	lactoylglutathione lyase activity
AN935_RS20595	COG0305	Participates in initiation and elongation during chromosome replication
AN935_RS20615	COG3093	addiction module antidote protein HigA
AN935_RS20620	COG2807	transmembrane transport
AN935_RS20625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AN935_RS20630	COG0359	binds to the 23S rRNA
AN935_RS20635	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AN935_RS20640	COG4241	membrane
AN935_RS20650	COG5577	PFAM Coat F domain
AN935_RS20655	COG1733	regulation of RNA biosynthetic process
AN935_RS20660	COG1227	inorganic diphosphatase activity
AN935_RS20675	COG2271	Major facilitator Superfamily
AN935_RS20685	COG4319	ketosteroid isomerase
AN935_RS20690	COG1357	PFAM Pentapeptide repeats (8 copies)
AN935_RS20695	COG2814	Major facilitator Superfamily
AN935_RS20700	COG0583	DNA-binding transcription factor activity
AN935_RS20705	COG2153	protein acetylation
AN935_RS20715	COG0583	DNA-binding transcription factor activity
AN935_RS20735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN935_RS20740	COG1733	regulation of RNA biosynthetic process
AN935_RS20745	COG1846	Transcriptional regulator
AN935_RS20750	COG2153	protein acetylation
AN935_RS20755	COG2364	Membrane
AN935_RS20770	COG2315	Protein conserved in bacteria
AN935_RS20780	COG0789	Transcriptional regulator
AN935_RS20800	COG2856	Zn peptidase
AN935_RS20810	COG1331	Highly conserved protein containing a thioredoxin domain
AN935_RS20815	COG1266	CAAX protease self-immunity
AN935_RS20820	COG0477	Major facilitator Superfamily
AN935_RS20820	COG2814	Major facilitator Superfamily
AN935_RS20825	COG0346	lactoylglutathione lyase activity
AN935_RS20830	COG1609	Transcriptional regulator
AN935_RS20835	COG0708	Exodeoxyribonuclease III
AN935_RS20840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AN935_RS20845	COG0629	single-stranded DNA binding
AN935_RS20850	COG0360	Binds together with S18 to 16S ribosomal RNA
AN935_RS20855	COG0012	GTP binding
AN935_RS20860	COG0243	molybdopterin cofactor binding
AN935_RS20865	COG4481	Protein conserved in bacteria
AN935_RS20870	COG3949	Membrane
AN935_RS20880	COG1475	DNA binding
AN935_RS20885	COG1192	Involved in chromosome partitioning
AN935_RS20895	COG1475	DNA binding
AN935_RS20900	COG0357	Ribosomal RNA small subunit methyltransferase G
AN935_RS20905	COG0445	tRNA wobble uridine modification
AN935_RS20910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AN935_RS20915	COG1847	R3H domain protein
AN935_RS20920	COG0706	membrane insertase activity
AN935_RS20925	COG0594	ribonuclease P activity
AN935_RS20935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AN935_RS20940	COG0592	DNA-directed DNA polymerase activity
AN935_RS20945	COG2501	S4 domain
AN935_RS20950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AN935_RS20960	COG0187	DNA topoisomerase II activity
AN935_RS20965	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AN935_RS21165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS21275	COG0071	Belongs to the small heat shock protein (HSP20) family
AN935_RS21365	COG4974	Belongs to the 'phage' integrase family
AN935_RS21625	COG1971	Probably functions as a manganese efflux pump
AN935_RS21765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS21780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS21780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS21820	COG1073	alpha beta
AN935_RS21830	COG5444	nuclease activity
AN935_RS21920	COG3321	synthase
AN935_RS21920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN935_RS21920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN935_RS21920	COG1028	Short-chain dehydrogenase reductase Sdr
AN935_RS21920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN935_RS21940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN935_RS21945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN935_RS22040	COG1396	sequence-specific DNA binding
AN935_RS22075	COG1024	Enoyl-CoA hydratase