locus-tag	class	description
N288_RS00010	COG0592	DNA-directed DNA polymerase activity
N288_RS00020	COG2501	S4 domain
N288_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N288_RS00035	COG0187	DNA topoisomerase II activity
N288_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N288_RS00080	COG0516	GMP reductase activity
N288_RS00080	COG0517	IMP dehydrogenase activity
N288_RS00090	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N288_RS00095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N288_RS00115	COG1428	Deoxynucleoside kinase
N288_RS00120	COG1428	Deoxynucleoside kinase
N288_RS00125	COG3858	chitin binding
N288_RS00125	COG1388	LysM domain
N288_RS00130	COG1335	isochorismatase
N288_RS00135	COG0590	tRNA wobble adenosine to inosine editing
N288_RS00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N288_RS00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N288_RS00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N288_RS00200	COG1982	Orn Lys Arg decarboxylase major
N288_RS00205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N288_RS00210	COG3870	Protein conserved in bacteria
N288_RS00215	COG1728	Protein conserved in bacteria
N288_RS00220	COG0470	DNA polymerase III
N288_RS00225	COG1774	PSP1 C-terminal conserved region
N288_RS00230	COG4467	Involved in initiation control of chromosome replication
N288_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N288_RS00240	COG2827	Endonuclease containing a URI domain
N288_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N288_RS00250	COG2002	toxin-antitoxin pair type II binding
N288_RS00260	COG0084	hydrolase, TatD family'
N288_RS00270	COG3583	domain protein
N288_RS00270	COG3584	3D domain protein
N288_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N288_RS00290	COG4466	Protein conserved in bacteria
N288_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N288_RS00310	COG0251	oxidation-reduction process
N288_RS00320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
N288_RS00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N288_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N288_RS00350	COG2002	toxin-antitoxin pair type II binding
N288_RS00355	COG2244	polysaccharide biosynthetic process
N288_RS00360	COG3956	TIGRFAM MazG family protein
N288_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N288_RS00385	COG1098	S1 RNA binding domain
N288_RS00400	COG2208	phosphoserine phosphatase activity
N288_RS00405	COG2304	oxidoreductase activity
N288_RS00410	COG0515	serine threonine protein kinase
N288_RS00415	COG0037	tRNA processing
N288_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N288_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N288_RS00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N288_RS00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N288_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N288_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N288_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N288_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
N288_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N288_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N288_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N288_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N288_RS00480	COG1396	sequence-specific DNA binding
N288_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N288_RS00575	COG3880	PFAM UvrB UvrC protein
N288_RS00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N288_RS00585	COG0542	response to heat
N288_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N288_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
N288_RS00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N288_RS00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N288_RS00620	COG1045	serine acetyltransferase
N288_RS00625	COG0215	cysteine-tRNA ligase activity
N288_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N288_RS00640	COG3688	RNA-binding protein containing a PIN domain
N288_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N288_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
N288_RS00670	COG0081	regulation of translation
N288_RS00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N288_RS00680	COG0222	ribosome binding
N288_RS00685	COG2813	Specifically methylates the guanine in position
N288_RS00695	COG0085	RNA polymerase activity
N288_RS00700	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N288_RS00705	COG1358	cellular component organization or biogenesis
N288_RS00710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N288_RS00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N288_RS00730	COG0051	transcription antitermination factor activity, RNA binding
N288_RS00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N288_RS00740	COG0088	Forms part of the polypeptide exit tunnel
N288_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N288_RS00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N288_RS00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N288_RS00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N288_RS00770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
N288_RS00775	COG0255	Belongs to the universal ribosomal protein uL29 family
N288_RS00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N288_RS00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N288_RS00800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N288_RS00805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N288_RS00810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N288_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N288_RS00820	COG1841	ribosomal large subunit assembly
N288_RS00825	COG0200	Binds to the 23S rRNA
N288_RS00830	COG0201	protein transport
N288_RS00835	COG0563	adenylate kinase activity
N288_RS00840	COG0024	Methionine aminopeptidase
N288_RS00845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
N288_RS00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N288_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N288_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N288_RS00870	COG0202	RNA polymerase activity
N288_RS00875	COG0203	ribosomal protein L17
N288_RS00880	COG1122	ATPase activity
N288_RS00885	COG1122	ATPase activity
N288_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N288_RS00895	COG0101	tRNA pseudouridine synthase activity
N288_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N288_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N288_RS00915	COG0860	N-Acetylmuramoyl-L-alanine amidase
N288_RS00920	COG0489	protein tyrosine kinase activity
N288_RS00930	COG2194	sulfuric ester hydrolase activity
N288_RS00935	COG0726	polysaccharide deacetylase
N288_RS01015	COG1595	DNA-templated transcription, initiation
N288_RS01020	COG5662	AntiSigma factor
N288_RS01025	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N288_RS01030	COG4856	YbbR-like protein
N288_RS01035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N288_RS01040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N288_RS01065	COG5566	PFAM Mor transcription activator
N288_RS01075	COG2323	membrane
N288_RS01080	COG0406	alpha-ribazole phosphatase activity
N288_RS01090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N288_RS01095	COG1968	undecaprenyl-diphosphatase activity
N288_RS01100	COG1301	dicarboxylic acid transport
N288_RS01110	COG0582	viral genome integration into host DNA
N288_RS01120	COG2706	6-phosphogluconolactonase activity
N288_RS01130	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS01145	COG3403	YqcI/YcgG family
N288_RS01150	COG0668	transmembrane transport
N288_RS01155	COG1595	DNA-templated transcription, initiation
N288_RS01165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N288_RS01170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS01175	COG1597	lipid kinase activity
N288_RS01185	COG0783	Belongs to the Dps family
N288_RS01190	COG1238	metal cluster binding
N288_RS01200	COG1695	Transcriptional regulator
N288_RS01205	COG0730	response to heat
N288_RS01210	COG0018	arginyl-trna synthetase
N288_RS01215	COG0772	Belongs to the SEDS family
N288_RS01230	COG2814	Major facilitator Superfamily
N288_RS01235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N288_RS01240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N288_RS01245	COG1120	ATPase activity
N288_RS01250	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
N288_RS01260	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
N288_RS01265	COG1492	cobalamin metabolic process
N288_RS01270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
N288_RS01280	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
N288_RS01285	COG2096	Adenosyltransferase
N288_RS01325	COG2076	Multidrug Resistance protein
N288_RS01330	COG1609	Transcriptional regulator
N288_RS01350	COG0395	ABC-type sugar transport system, permease component
N288_RS01355	COG0346	lactoylglutathione lyase activity
N288_RS01365	COG0659	secondary active sulfate transmembrane transporter activity
N288_RS01370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N288_RS01380	COG1181	Belongs to the D-alanine--D-alanine ligase family
N288_RS01385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N288_RS01395	COG1595	DNA-templated transcription, initiation
N288_RS01415	COG0513	Belongs to the DEAD box helicase family
N288_RS01420	COG4294	response to UV
N288_RS01425	COG3402	PFAM membrane-flanked domain
N288_RS01430	COG3428	Bacterial PH domain
N288_RS01435	COG0705	Rhomboid family
N288_RS01445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N288_RS01455	COG0864	Transcriptional regulator
N288_RS01460	COG2337	Toxic component of a toxin-antitoxin (TA) module
N288_RS01465	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS01470	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS01475	COG2172	sigma factor antagonist activity
N288_RS01480	COG2208	phosphoserine phosphatase activity
N288_RS01485	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS01490	COG2172	sigma factor antagonist activity
N288_RS01495	COG1191	sigma factor activity
N288_RS01500	COG2208	phosphoserine phosphatase activity
N288_RS01505	COG2183	response to ionizing radiation
N288_RS01510	COG3091	SprT-like family
N288_RS01585	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N288_RS01595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N288_RS01600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N288_RS01605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N288_RS01610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N288_RS01615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N288_RS01620	COG0047	phosphoribosylformylglycinamidine synthase activity
N288_RS01625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N288_RS01630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N288_RS01635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N288_RS01640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N288_RS01650	COG0151	Belongs to the GarS family
N288_RS01665	COG1470	cell adhesion involved in biofilm formation
N288_RS01670	COG4496	protein, YerC YecD
N288_RS01680	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N288_RS01685	COG0210	DNA helicase
N288_RS01690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N288_RS01695	COG4851	CamS sex pheromone cAM373 precursor
N288_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS01715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N288_RS01720	COG2224	Isocitrate lyase
N288_RS01725	COG5506	Protein of unknown function (DUF1694)
N288_RS01745	COG2814	Major facilitator Superfamily
N288_RS01750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N288_RS01755	COG0154	amidase activity
N288_RS01780	COG1301	dicarboxylic acid transport
N288_RS01785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N288_RS01790	COG4106	trans-aconitate 2-methyltransferase activity
N288_RS01795	COG0681	Belongs to the peptidase S26 family
N288_RS01800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N288_RS01810	COG1522	sequence-specific DNA binding
N288_RS01820	COG1335	isochorismatase
N288_RS01825	COG1595	DNA-templated transcription, initiation
N288_RS01850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N288_RS01870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS01875	COG1309	transcriptional regulator
N288_RS01880	COG1597	lipid kinase activity
N288_RS01895	COG2066	Belongs to the glutaminase family
N288_RS01905	COG2814	Major facilitator Superfamily
N288_RS01910	COG0778	Nitroreductase
N288_RS01915	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N288_RS01920	COG1280	lysine exporter protein (LysE YggA)
N288_RS01925	COG0166	Belongs to the GPI family
N288_RS01945	COG0492	ferredoxin-NADP+ reductase activity
N288_RS01965	COG1595	DNA-templated transcription, initiation
N288_RS01985	COG1595	DNA-templated transcription, initiation
N288_RS01995	COG2814	Major facilitator Superfamily
N288_RS02000	COG1846	Transcriptional regulator
N288_RS02005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N288_RS02010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N288_RS02010	COG2169	Transcriptional regulator
N288_RS02015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N288_RS02020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N288_RS02035	COG1609	Transcriptional regulator
N288_RS02045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N288_RS02050	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N288_RS02075	COG2130	NADP-dependent
N288_RS02080	COG2207	Transcriptional regulator
N288_RS02080	COG4753	response regulator
N288_RS02085	COG2972	Histidine kinase
N288_RS02105	COG3250	beta-galactosidase activity
N288_RS02120	COG2186	Transcriptional regulator
N288_RS02125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N288_RS02130	COG0385	Bile acid
N288_RS02135	COG0501	Belongs to the peptidase M48B family
N288_RS02145	COG2814	Major facilitator Superfamily
N288_RS02160	COG1131	(ABC) transporter
N288_RS02175	COG1595	DNA-templated transcription, initiation
N288_RS02190	COG2321	neutral zinc metallopeptidase
N288_RS02195	COG4297	protein containing double-stranded beta helix domain
N288_RS02205	COG0110	maltose O-acetyltransferase activity
N288_RS02230	COG5002	protein histidine kinase activity
N288_RS02245	COG0604	alcohol dehydrogenase
N288_RS02255	COG1842	Phage shock protein A
N288_RS02260	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS02290	COG0494	nUDIX hydrolase
N288_RS02305	COG1764	response to oxidative stress
N288_RS02310	COG1846	Transcriptional regulator
N288_RS02355	COG3813	Protein conserved in bacteria
N288_RS02385	COG1247	-acetyltransferase
N288_RS02405	COG0753	catalase activity
N288_RS02410	COG2199	diguanylate cyclase activity
N288_RS02420	COG2124	cytochrome p450
N288_RS02435	COG3344	reverse transcriptase
N288_RS02440	COG1704	LemA family
N288_RS02465	COG1966	Carbon starvation protein
N288_RS02475	COG0546	phosphoglycolate phosphatase activity
N288_RS02500	COG5434	Belongs to the glycosyl hydrolase 28 family
N288_RS02505	COG3885	ferrous iron binding
N288_RS02505	COG2078	PFAM AMMECR1 domain protein
N288_RS02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N288_RS02515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N288_RS02530	COG0217	transcriptional regulatory protein
N288_RS02540	COG0346	lactoylglutathione lyase activity
N288_RS02560	COG0598	Magnesium transport protein CorA
N288_RS02570	COG5001	Diguanylate cyclase
N288_RS02570	COG3300	MHYT domain
N288_RS02575	COG0789	Transcriptional regulator
N288_RS02580	COG1733	regulation of RNA biosynthetic process
N288_RS02585	COG2814	Major facilitator Superfamily
N288_RS02590	COG0656	L-ascorbic acid biosynthetic process
N288_RS02595	COG2304	oxidoreductase activity
N288_RS02600	COG0386	Belongs to the glutathione peroxidase family
N288_RS02615	COG3104	oligopeptide transport
N288_RS02620	COG0778	Nitroreductase
N288_RS02635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N288_RS02665	COG2814	Major facilitator Superfamily
N288_RS02670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N288_RS02675	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
N288_RS02680	COG1160	GTP binding
N288_RS02685	COG4682	membrane
N288_RS02690	COG1131	(ABC) transporter
N288_RS02695	COG0842	Transport permease protein
N288_RS02700	COG4585	Histidine kinase
N288_RS02705	COG2197	response regulator
N288_RS02715	COG0527	aspartate kinase activity
N288_RS02735	COG1562	ergosterol biosynthetic process
N288_RS02775	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS02795	COG0725	ABC transporter, periplasmic molybdate-binding protein
N288_RS02800	COG1388	LysM domain
N288_RS02805	COG1476	TRANSCRIPTIONal
N288_RS02815	COG1131	(ABC) transporter
N288_RS02840	COG1595	DNA-templated transcription, initiation
N288_RS02850	COG0406	alpha-ribazole phosphatase activity
N288_RS02870	COG1131	(ABC) transporter
N288_RS02875	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N288_RS02885	COG2318	DinB family
N288_RS02890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N288_RS02905	COG2205	protein histidine kinase activity
N288_RS02910	COG0745	RESPONSE REGULATOR receiver
N288_RS02915	COG2311	Membrane
N288_RS02920	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
N288_RS02930	COG1073	alpha beta
N288_RS02930	COG2226	methyltransferase
N288_RS02935	COG0025	NhaP-type Na H and K H
N288_RS02940	COG2966	Psort location CytoplasmicMembrane, score
N288_RS02945	COG3610	response to peptide
N288_RS02950	COG1132	(ABC) transporter
N288_RS02955	COG1132	(ABC) transporter
N288_RS02960	COG1115	amino acid carrier protein
N288_RS02975	COG0697	spore germination
N288_RS02980	COG1522	sequence-specific DNA binding
N288_RS02985	COG0352	thiamine-phosphate diphosphorylase activity
N288_RS02990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N288_RS03000	COG2022	thiamine diphosphate biosynthetic process
N288_RS03005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N288_RS03025	COG1063	alcohol dehydrogenase
N288_RS03040	COG0154	amidase activity
N288_RS03050	COG1695	Transcriptional regulator
N288_RS03080	COG0723	plastoquinol--plastocyanin reductase activity
N288_RS03080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N288_RS03090	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N288_RS03095	COG0697	spore germination
N288_RS03115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N288_RS03120	COG1657	PFAM Prenyltransferase squalene oxidase
N288_RS03125	COG1994	Peptidase M50
N288_RS03150	COG2197	response regulator
N288_RS03165	COG0488	(ABC) transporter
N288_RS03170	COG3546	catalase activity
N288_RS03185	COG2244	polysaccharide biosynthetic process
N288_RS03195	COG1595	DNA-templated transcription, initiation
N288_RS03210	COG0598	Magnesium transport protein CorA
N288_RS03215	COG0300	oxidoreductase activity
N288_RS03220	COG1309	transcriptional regulator
N288_RS03225	COG1607	acyl-coa hydrolase
N288_RS03240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N288_RS03250	COG0805	protein transport
N288_RS03255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N288_RS03315	COG0670	Belongs to the BI1 family
N288_RS03320	COG1970	mechanosensitive ion channel activity
N288_RS03325	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N288_RS03330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N288_RS03340	COG4145	pantothenate transmembrane transporter activity
N288_RS03345	COG1254	Belongs to the acylphosphatase family
N288_RS03355	COG2309	aminopeptidase activity
N288_RS03380	COG1183	phosphatidylcholine synthase activity
N288_RS03385	COG2986	histidine ammonia-lyase
N288_RS03390	COG0450	alkyl hydroperoxide reductase
N288_RS03395	COG0450	alkyl hydroperoxide reductase
N288_RS03400	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N288_RS03410	COG2323	membrane
N288_RS03415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N288_RS03420	COG1360	Flagellar Motor Protein
N288_RS03425	COG2211	Major facilitator Superfamily
N288_RS03435	COG2814	Major facilitator Superfamily
N288_RS03445	COG1115	amino acid carrier protein
N288_RS03450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N288_RS03450	COG1522	sequence-specific DNA binding
N288_RS03455	COG2313	pseudouridylate synthase activity
N288_RS03460	COG3764	Sortase (surface protein transpeptidase)
N288_RS03465	COG1396	sequence-specific DNA binding
N288_RS03470	COG0681	Belongs to the peptidase S26 family
N288_RS03505	COG1960	acyl-CoA dehydrogenase activity
N288_RS03515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N288_RS03520	COG4106	trans-aconitate 2-methyltransferase activity
N288_RS03530	COG2188	Transcriptional regulator
N288_RS03535	COG3486	L-lysine 6-monooxygenase (NADPH) activity
N288_RS03540	COG0693	protein deglycase activity
N288_RS03545	COG0024	Methionine aminopeptidase
N288_RS03550	COG2226	methyltransferase
N288_RS03560	COG4840	Belongs to the UPF0435 family
N288_RS03565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N288_RS03575	COG1295	ribonuclease BN
N288_RS03585	COG2217	Heavy metal translocating P-type atpase
N288_RS03590	COG0477	Major facilitator Superfamily
N288_RS03600	COG3871	stress protein (general stress protein 26)
N288_RS03605	COG0387	Pfam Sodium calcium exchanger
N288_RS03610	COG2364	Membrane
N288_RS03620	COG0346	lactoylglutathione lyase activity
N288_RS03670	COG0535	radical SAM domain protein
N288_RS03680	COG0405	Gamma-glutamyltransferase
N288_RS03685	COG2323	membrane
N288_RS03705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N288_RS03710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N288_RS03740	COG1129	ABC transporter
N288_RS03745	COG4211	Belongs to the binding-protein-dependent transport system permease family
N288_RS03750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N288_RS03765	COG0488	(ABC) transporter
N288_RS03875	COG0305	Participates in initiation and elongation during chromosome replication
N288_RS03920	COG2205	protein histidine kinase activity
N288_RS03975	COG0640	Transcriptional regulator
N288_RS03980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N288_RS03985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N288_RS04010	COG5002	protein histidine kinase activity
N288_RS04035	COG5505	Protein of unknown function (DUF819)
N288_RS04045	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS04060	COG0693	protein deglycase activity
N288_RS04095	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N288_RS04100	COG4605	iron ion homeostasis
N288_RS04105	COG4604	ABC transporter, ATP-binding protein
N288_RS04110	COG4607	ABC-type enterochelin transport system periplasmic component
N288_RS04115	COG4122	O-methyltransferase activity
N288_RS04120	COG2329	Antibiotic biosynthesis monooxygenase
N288_RS04125	COG2203	Gaf domain
N288_RS04125	COG2199	diguanylate cyclase activity
N288_RS04155	COG0514	ATP-dependent DNA helicase (RecQ)
N288_RS04170	COG0494	nUDIX hydrolase
N288_RS04195	COG1228	amidohydrolase
N288_RS04200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N288_RS04205	COG0006	proline dipeptidase activity
N288_RS04270	COG2207	Transcriptional regulator
N288_RS04275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS04305	COG3443	Belongs to the bacterial solute-binding protein 9 family
N288_RS04310	COG0861	Integral membrane protein TerC family
N288_RS04325	COG2816	NAD+ diphosphatase activity
N288_RS04355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N288_RS04375	COG0656	L-ascorbic acid biosynthetic process
N288_RS04385	COG0300	oxidoreductase activity
N288_RS04405	COG1595	DNA-templated transcription, initiation
N288_RS04410	COG0860	N-Acetylmuramoyl-L-alanine amidase
N288_RS04420	COG0840	transmembrane signaling receptor activity
N288_RS04425	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N288_RS04440	COG0069	glutamate synthase activity
N288_RS04445	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N288_RS04510	COG1278	Cold shock
N288_RS04520	COG3239	Fatty acid desaturase
N288_RS04545	COG0596	Alpha beta hydrolase
N288_RS04565	COG5002	protein histidine kinase activity
N288_RS04570	COG0745	RESPONSE REGULATOR receiver
N288_RS04580	COG3507	Belongs to the glycosyl hydrolase 43 family
N288_RS04585	COG1940	carbohydrate kinase activity
N288_RS04595	COG1175	transmembrane transport
N288_RS04600	COG0395	ABC-type sugar transport system, permease component
N288_RS04605	COG5578	integral membrane protein
N288_RS04610	COG2115	Belongs to the xylose isomerase family
N288_RS04615	COG1070	Carbohydrate kinase
N288_RS04620	COG0667	Aldo Keto reductase
N288_RS04625	COG2814	Major facilitator Superfamily
N288_RS04625	COG0477	Major facilitator Superfamily
N288_RS04630	COG0730	response to heat
N288_RS04635	COG3290	protein histidine kinase activity
N288_RS04640	COG4565	transcriptional regulatory protein
N288_RS04645	COG3493	citrate carrier protein
N288_RS04650	COG0281	malic enzyme
N288_RS04655	COG3173	Aminoglycoside phosphotransferase
N288_RS04665	COG3706	GGDEF domain
N288_RS04690	COG0488	(ABC) transporter
N288_RS04695	COG1126	abc transporter atp-binding protein
N288_RS04700	COG0765	amino acid transport
N288_RS04705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N288_RS04710	COG3173	Aminoglycoside phosphotransferase
N288_RS04725	COG0488	(ABC) transporter
N288_RS04730	COG4807	Protein conserved in bacteria
N288_RS04745	COG1250	3-hydroxyacyl-CoA dehydrogenase
N288_RS04745	COG1024	Enoyl-CoA hydratase
N288_RS04750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N288_RS04755	COG2272	Belongs to the type-B carboxylesterase lipase family
N288_RS04760	COG3835	regulator
N288_RS04765	COG2610	gluconate transmembrane transporter activity
N288_RS04770	COG1929	Belongs to the glycerate kinase type-1 family
N288_RS04775	COG2172	sigma factor antagonist activity
N288_RS04795	COG3459	Glycosyltransferase 36 associated
N288_RS04805	COG1653	transport
N288_RS04810	COG1175	transmembrane transport
N288_RS04815	COG0395	ABC-type sugar transport system, permease component
N288_RS04825	COG1609	Transcriptional regulator
N288_RS04830	COG1757	Na H antiporter
N288_RS04850	COG2723	6-phospho-beta-galactosidase activity
N288_RS04860	COG0142	geranyltranstransferase activity
N288_RS04870	COG0861	Integral membrane protein TerC family
N288_RS04875	COG0300	oxidoreductase activity
N288_RS04890	COG1473	amidohydrolase
N288_RS04895	COG0456	acetyltransferase
N288_RS04900	COG0435	Glutathione S-transferase
N288_RS04930	COG2207	Transcriptional regulator
N288_RS04940	COG0243	molybdopterin cofactor binding
N288_RS04945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N288_RS04985	COG2186	Transcriptional regulator
N288_RS04990	COG1620	l-lactate permease
N288_RS04995	COG0247	lactate metabolic process
N288_RS05000	COG1139	Iron-sulfur cluster binding protein
N288_RS05005	COG1556	Lactate utilization protein
N288_RS05025	COG1073	alpha beta
N288_RS05030	COG1263	PTS System
N288_RS05030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N288_RS05050	COG1566	PFAM secretion protein HlyD family protein
N288_RS05055	COG0655	NAD(P)H dehydrogenase (quinone) activity
N288_RS05065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N288_RS05070	COG0765	amino acid transport
N288_RS05075	COG1126	abc transporter atp-binding protein
N288_RS05080	COG2832	Protein of unknown function (DUF454)
N288_RS05095	COG1757	Na H antiporter
N288_RS05100	COG3832	glyoxalase III activity
N288_RS05140	COG0861	Integral membrane protein TerC family
N288_RS05150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N288_RS05155	COG1522	sequence-specific DNA binding
N288_RS05165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N288_RS05170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N288_RS05175	COG2182	Extracellular solute-binding protein
N288_RS05185	COG3842	ATPase activity
N288_RS05190	COG1175	transmembrane transport
N288_RS05195	COG0395	ABC-type sugar transport system, permease component
N288_RS05200	COG0584	glycerophosphoryl diester phosphodiesterase
N288_RS05205	COG0463	Glycosyl transferase, family 2
N288_RS05215	COG4485	Bacterial membrane protein, YfhO
N288_RS05230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N288_RS05235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N288_RS05250	COG1695	Transcriptional regulator
N288_RS05265	COG1090	epimerase
N288_RS05275	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS05295	COG1988	membrane-bound metal-dependent
N288_RS05305	COG1194	a g-specific adenine glycosylase
N288_RS05315	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS05335	COG1132	(ABC) transporter
N288_RS05340	COG0444	Belongs to the ABC transporter superfamily
N288_RS05345	COG4608	Belongs to the ABC transporter superfamily
N288_RS05350	COG0747	negative chemotaxis
N288_RS05355	COG0601	transmembrane transport
N288_RS05360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS05365	COG4129	membrane
N288_RS05370	COG0070	glutamate synthase
N288_RS05370	COG0069	glutamate synthase activity
N288_RS05370	COG0067	glutamate synthase
N288_RS05375	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N288_RS05380	COG4555	ABC transporter
N288_RS05405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N288_RS05415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N288_RS05425	COG0735	belongs to the Fur family
N288_RS05550	COG2972	Histidine kinase
N288_RS05555	COG4753	response regulator
N288_RS05555	COG2207	Transcriptional regulator
N288_RS05565	COG0673	inositol 2-dehydrogenase activity
N288_RS05570	COG0673	inositol 2-dehydrogenase activity
N288_RS05575	COG3382	B3 4 domain protein
N288_RS05580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N288_RS05590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N288_RS05595	COG0778	Nitroreductase
N288_RS05600	COG2766	serine protein kinase
N288_RS05610	COG2718	Belongs to the UPF0229 family
N288_RS05620	COG2310	stress, protein
N288_RS05630	COG0656	L-ascorbic acid biosynthetic process
N288_RS05655	COG2094	Belongs to the DNA glycosylase MPG family
N288_RS05660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N288_RS05695	COG0745	RESPONSE REGULATOR receiver
N288_RS05700	COG5002	protein histidine kinase activity
N288_RS05705	COG1823	symporter activity
N288_RS05710	COG2226	methyltransferase
N288_RS05715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS05725	COG2252	PERMEase
N288_RS05730	COG4187	Peptidase family M20/M25/M40
N288_RS05740	COG0745	RESPONSE REGULATOR receiver
N288_RS05745	COG2205	protein histidine kinase activity
N288_RS05755	COG1609	Transcriptional regulator
N288_RS05765	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
N288_RS05770	COG1737	Transcriptional regulator
N288_RS05775	COG2610	gluconate transmembrane transporter activity
N288_RS05780	COG1070	Carbohydrate kinase
N288_RS05785	COG0306	phosphate transporter
N288_RS05790	COG1392	Phosphate transport regulator
N288_RS05795	COG3973	AAA domain
N288_RS05805	COG2261	transglycosylase associated protein
N288_RS05810	COG0564	pseudouridine synthase activity
N288_RS05820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS05825	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N288_RS05835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N288_RS05835	COG3153	acetyltransferase
N288_RS05840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N288_RS05845	COG4585	Histidine kinase
N288_RS05845	COG2203	Gaf domain
N288_RS05850	COG2197	response regulator
N288_RS05855	COG0431	NADPH-dependent FMN reductase
N288_RS05875	COG2719	SpoVR family
N288_RS05885	COG0492	ferredoxin-NADP+ reductase activity
N288_RS05920	COG3118	belongs to the thioredoxin family
N288_RS05920	COG0492	ferredoxin-NADP+ reductase activity
N288_RS05935	COG1309	transcriptional regulator
N288_RS05940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N288_RS05950	COG1695	Transcriptional regulator
N288_RS05960	COG2112	serine threonine protein kinase
N288_RS05985	COG3290	protein histidine kinase activity
N288_RS05990	COG3279	Response regulator of the LytR AlgR family
N288_RS05995	COG4555	ABC transporter
N288_RS06000	COG1668	transmembrane transport
N288_RS06005	COG2814	Major facilitator Superfamily
N288_RS06015	COG1295	ribonuclease BN
N288_RS06020	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N288_RS06025	COG2252	PERMEase
N288_RS06030	COG0778	Nitroreductase
N288_RS06050	COG0745	RESPONSE REGULATOR receiver
N288_RS06055	COG5002	protein histidine kinase activity
N288_RS06055	COG3850	Histidine kinase
N288_RS06060	COG1253	flavin adenine dinucleotide binding
N288_RS06065	COG0789	Transcriptional regulator
N288_RS06070	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS06075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS06090	COG0589	response to stress
N288_RS06095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N288_RS06105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N288_RS06110	COG2213	PTS system mannitol-specific
N288_RS06110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS06115	COG3711	transcriptional antiterminator
N288_RS06120	COG0246	Mannitol dehydrogenase
N288_RS06125	COG2814	Major facilitator Superfamily
N288_RS06130	COG0662	Cupin 2, conserved barrel domain protein
N288_RS06140	COG0546	phosphoglycolate phosphatase activity
N288_RS06155	COG1595	DNA-templated transcription, initiation
N288_RS06175	COG0393	Putative heavy-metal-binding
N288_RS06180	COG1132	(ABC) transporter
N288_RS06185	COG1132	(ABC) transporter
N288_RS06205	COG3842	ATPase activity
N288_RS06210	COG2508	Transcriptional regulator
N288_RS06215	COG1937	Protein conserved in bacteria
N288_RS06230	COG0189	ligase activity
N288_RS06235	COG0189	ligase activity
N288_RS06240	COG0189	ligase activity
N288_RS06245	COG0189	ligase activity
N288_RS06250	COG4399	Belongs to the UPF0754 family
N288_RS06270	COG1090	epimerase
N288_RS06275	COG0561	phosphatase activity
N288_RS06280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N288_RS06285	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N288_RS06290	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS06295	COG1024	Enoyl-CoA hydratase
N288_RS06305	COG4152	abc transporter atp-binding protein
N288_RS06310	COG1668	transmembrane transport
N288_RS06315	COG1280	lysine exporter protein (LysE YggA)
N288_RS06330	COG0420	3'-5' exonuclease activity
N288_RS06335	COG4717	serine-type aminopeptidase activity
N288_RS06340	COG3481	metal-dependent phosphohydrolase, HD sub domain
N288_RS06355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N288_RS06385	COG1846	Transcriptional regulator
N288_RS06405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N288_RS06410	COG0537	adenosine 5'-monophosphoramidase activity
N288_RS06420	COG1131	(ABC) transporter
N288_RS06425	COG4473	ABC transporter
N288_RS06435	COG1473	amidohydrolase
N288_RS06440	COG0671	phosphoesterase, PA-phosphatase related
N288_RS06450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N288_RS06455	COG4191	Histidine kinase
N288_RS06460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N288_RS06465	COG2720	vancomycin resistance protein
N288_RS06475	COG2304	oxidoreductase activity
N288_RS06480	COG2861	carbohydrate metabolic process
N288_RS06495	COG4895	conserved protein (DUF2196)
N288_RS06500	COG3069	C4-dicarboxylate transmembrane transporter activity
N288_RS06510	COG4585	Histidine kinase
N288_RS06515	COG2197	response regulator
N288_RS06520	COG2329	Antibiotic biosynthesis monooxygenase
N288_RS06530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N288_RS06535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N288_RS06540	COG1309	transcriptional regulator
N288_RS06545	COG1511	domain protein
N288_RS06550	COG1234	tRNA 3'-trailer cleavage
N288_RS06555	COG0095	Lipoate-protein ligase
N288_RS06560	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS06565	COG1024	Enoyl-CoA hydratase
N288_RS06575	COG4120	Belongs to the binding-protein-dependent transport system permease family
N288_RS06580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N288_RS06585	COG1396	sequence-specific DNA binding
N288_RS06590	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N288_RS06600	COG0501	Belongs to the peptidase M48B family
N288_RS06615	COG4903	ComK protein
N288_RS06625	COG1506	peptidase
N288_RS06625	COG4946	Tricorn protease homolog
N288_RS06625	COG0823	Involved in the tonB-independent uptake of proteins
N288_RS06635	COG0398	Pfam SNARE associated Golgi protein
N288_RS06670	COG0559	Belongs to the binding-protein-dependent transport system permease family
N288_RS06685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N288_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS06700	COG0183	Belongs to the thiolase family
N288_RS06705	COG1335	isochorismatase
N288_RS06710	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS06725	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N288_RS06730	COG1074	ATP-dependent DNA helicase activity
N288_RS06735	COG1403	HNH endonuclease
N288_RS06770	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS06775	COG2311	Membrane
N288_RS06785	COG0179	Fumarylacetoacetate (FAA) hydrolase
N288_RS06800	COG4585	Histidine kinase
N288_RS06805	COG2197	response regulator
N288_RS06810	COG1131	(ABC) transporter
N288_RS06815	COG1511	domain protein
N288_RS06815	COG0842	Transport permease protein
N288_RS06830	COG0367	asparagine synthase
N288_RS06845	COG1562	ergosterol biosynthetic process
N288_RS06850	COG0534	Mate efflux family protein
N288_RS06860	COG2182	Extracellular solute-binding protein
N288_RS06865	COG1175	transmembrane transport
N288_RS06870	COG3833	ABC-type maltose transport systems, permease component
N288_RS06875	COG1874	Beta-galactosidase
N288_RS06875	COG0366	Alpha amylase catalytic
N288_RS06885	COG1609	Transcriptional regulator
N288_RS06890	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS06900	COG1666	GTP binding
N288_RS06905	COG2996	Protein conserved in bacteria
N288_RS06910	COG1307	EDD domain protein, DegV family
N288_RS06915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS06930	COG0561	phosphatase activity
N288_RS06935	COG1073	alpha beta
N288_RS06940	COG2151	metal-sulfur cluster biosynthetic enzyme
N288_RS06950	COG0303	'Molybdopterin
N288_RS06960	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N288_RS06965	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N288_RS06990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N288_RS07015	COG2267	carboxylic ester hydrolase activity
N288_RS07025	COG1744	ABC transporter substrate-binding protein PnrA-like
N288_RS07040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N288_RS07045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N288_RS07050	COG5504	Zn-dependent protease
N288_RS07055	COG0444	Belongs to the ABC transporter superfamily
N288_RS07060	COG4608	Belongs to the ABC transporter superfamily
N288_RS07070	COG0601	transmembrane transport
N288_RS07075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS07090	COG0180	Tryptophanyl-tRNA synthetase
N288_RS07095	COG4166	transmembrane transport
N288_RS07100	COG0601	transmembrane transport
N288_RS07105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS07110	COG0444	Belongs to the ABC transporter superfamily
N288_RS07115	COG4608	Belongs to the ABC transporter superfamily
N288_RS07130	COG0456	acetyltransferase
N288_RS07135	COG1393	Belongs to the ArsC family
N288_RS07140	COG4862	establishment of competence for transformation
N288_RS07145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N288_RS07155	COG1164	Oligoendopeptidase f
N288_RS07165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N288_RS07170	COG2346	COG2346, Truncated hemoglobins
N288_RS07175	COG0741	lytic transglycosylase activity
N288_RS07180	COG4116	CYTH
N288_RS07190	COG2357	RelA SpoT domain protein
N288_RS07200	COG0564	pseudouridine synthase activity
N288_RS07205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N288_RS07210	COG2239	Acts as a magnesium transporter
N288_RS07215	COG0475	glutathione-regulated potassium exporter activity
N288_RS07215	COG0569	domain protein
N288_RS07220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N288_RS07250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N288_RS07260	COG2323	membrane
N288_RS07270	COG1960	acyl-CoA dehydrogenase activity
N288_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS07280	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS07285	COG1309	transcriptional regulator
N288_RS07290	COG1250	3-hydroxyacyl-CoA dehydrogenase
N288_RS07295	COG1024	Enoyl-CoA hydratase
N288_RS07315	COG1960	acyl-CoA dehydrogenase activity
N288_RS07335	COG0210	DNA helicase
N288_RS07345	COG2323	membrane
N288_RS07350	COG2153	protein acetylation
N288_RS07355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N288_RS07360	COG2382	esterase
N288_RS07365	COG2358	TRAP transporter, solute receptor (TAXI family
N288_RS07385	COG3842	ATPase activity
N288_RS07400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N288_RS07415	COG2362	D-Aminopeptidase
N288_RS07420	COG0601	transmembrane transport
N288_RS07425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS07430	COG0444	Belongs to the ABC transporter superfamily
N288_RS07435	COG4166	transmembrane transport
N288_RS07440	COG1619	proteins homologs of microcin C7 resistance protein MccF
N288_RS07445	COG4948	Mandelate Racemase Muconate Lactonizing
N288_RS07450	COG0791	NLP P60 protein
N288_RS07455	COG4608	Belongs to the ABC transporter superfamily
N288_RS07475	COG0546	phosphoglycolate phosphatase activity
N288_RS07480	COG3871	stress protein (general stress protein 26)
N288_RS07500	COG0697	spore germination
N288_RS07520	COG4242	Belongs to the peptidase S51 family
N288_RS07535	COG0584	glycerophosphoryl diester phosphodiesterase
N288_RS07550	COG1585	Membrane protein implicated in regulation of membrane protease activity
N288_RS07555	COG2268	Band 7 protein
N288_RS07585	COG1404	Belongs to the peptidase S8 family
N288_RS07585	COG4412	M6 family metalloprotease domain protein
N288_RS07590	COG1595	DNA-templated transcription, initiation
N288_RS07600	COG1653	transport
N288_RS07605	COG1175	transmembrane transport
N288_RS07610	COG0395	ABC-type sugar transport system, permease component
N288_RS07625	COG1116	anion transmembrane transporter activity
N288_RS07630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N288_RS07645	COG3773	Cell wall hydrolase
N288_RS07655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N288_RS07660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N288_RS07660	COG1263	PTS System
N288_RS07665	COG0366	Alpha amylase catalytic
N288_RS07670	COG0366	Alpha amylase catalytic
N288_RS07675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N288_RS07680	COG1988	membrane-bound metal-dependent
N288_RS07685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N288_RS07690	COG2200	EAL domain
N288_RS07695	COG0456	acetyltransferase
N288_RS07700	COG1757	Na H antiporter
N288_RS07705	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N288_RS07710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N288_RS07725	COG1191	sigma factor activity
N288_RS07740	COG0247	lactate metabolic process
N288_RS07745	COG0277	FAD linked oxidase domain protein
N288_RS07750	COG3835	regulator
N288_RS07755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N288_RS07770	COG3594	Acyltransferase
N288_RS07775	COG0840	transmembrane signaling receptor activity
N288_RS07785	COG5002	protein histidine kinase activity
N288_RS07800	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N288_RS07805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N288_RS07810	COG0436	Aminotransferase
N288_RS07815	COG1850	ribulose-bisphosphate carboxylase activity
N288_RS07820	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N288_RS07825	COG0235	Class ii aldolase
N288_RS07850	COG2223	nitrite transmembrane transporter activity
N288_RS07855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N288_RS07860	COG3852	Histidine kinase
N288_RS07865	COG0737	Belongs to the 5'-nucleotidase family
N288_RS07870	COG1846	Transcriptional regulator
N288_RS07880	COG5002	protein histidine kinase activity
N288_RS07885	COG0542	response to heat
N288_RS07890	COG3949	Membrane
N288_RS07905	COG0702	epimerase
N288_RS07910	COG4873	Protein conserved in bacteria
N288_RS07920	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS07930	COG0714	Associated with various cellular activities
N288_RS07955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N288_RS07960	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS07970	COG2084	Dehydrogenase
N288_RS07975	COG0436	Aminotransferase
N288_RS07980	COG1714	RDD family
N288_RS08000	COG0835	chemotaxis
N288_RS08000	COG0784	Response regulator, receiver
N288_RS08010	COG2814	Major facilitator Superfamily
N288_RS08020	COG1376	ErfK ybiS ycfS ynhG family protein
N288_RS08025	COG1408	metallophosphoesterase
N288_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS08035	COG4990	cell redox homeostasis
N288_RS08045	COG2200	EAL domain
N288_RS08070	COG4703	Protein of unknown function (DUF1797)
N288_RS08075	COG0517	IMP dehydrogenase activity
N288_RS08085	COG0583	DNA-binding transcription factor activity
N288_RS08090	COG2171	N-acyltransferase activity
N288_RS08095	COG1473	amidohydrolase
N288_RS08100	COG0668	transmembrane transport
N288_RS08105	COG1132	(ABC) transporter
N288_RS08110	COG1132	(ABC) transporter
N288_RS08120	COG1271	oxidase subunit
N288_RS08125	COG1294	oxidase, subunit
N288_RS08130	COG0569	domain protein
N288_RS08135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N288_RS08140	COG5503	Protein of unknown function (DUF1447)
N288_RS08145	COG0697	spore germination
N288_RS08150	COG0561	phosphatase activity
N288_RS08155	COG0242	peptide deformylase activity
N288_RS08165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N288_RS08175	COG0508	dehydrogenase complex catalyzes the overall conversion of
N288_RS08185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS08195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N288_RS08200	COG0726	polysaccharide deacetylase
N288_RS08215	COG1982	Orn Lys Arg decarboxylase major
N288_RS08225	COG4476	Belongs to the UPF0223 family
N288_RS08230	COG4493	Belongs to the UPF0637 family
N288_RS08240	COG0483	inositol monophosphate 1-phosphatase activity
N288_RS08255	COG1217	gtp-binding protein TYPA
N288_RS08275	COG4896	Protein conserved in bacteria
N288_RS08290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N288_RS08295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N288_RS08300	COG4838	Belongs to the UPF0358 family
N288_RS08305	COG0772	Belongs to the SEDS family
N288_RS08310	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N288_RS08315	COG1612	heme a metabolic process
N288_RS08345	COG3336	cytochrome c oxidase
N288_RS08360	COG0628	permease
N288_RS08370	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N288_RS08375	COG2340	Cysteine-rich secretory protein family
N288_RS08405	COG3679	Belongs to the UPF0342 family
N288_RS08410	COG4471	UPF0298 protein
N288_RS08425	COG0742	ribosomal rna small subunit methyltransferase
N288_RS08430	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N288_RS08435	COG3314	Sporulation integral membrane protein YlbJ
N288_RS08440	COG1752	Esterase of the alpha-beta hydrolase superfamily
N288_RS08445	COG3480	Lon protease (S16) C-terminal proteolytic domain
N288_RS08450	COG1323	Belongs to the UPF0348 family
N288_RS08455	COG1399	metal-binding, possibly nucleic acid-binding protein
N288_RS08460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N288_RS08465	COG1024	Enoyl-CoA hydratase
N288_RS08475	COG0454	-acetyltransferase
N288_RS08480	COG0439	Biotin carboxylase
N288_RS08485	COG0511	ligase activity, forming carbon-carbon bonds
N288_RS08490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N288_RS08495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N288_RS08505	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N288_RS08515	COG2001	Belongs to the MraZ family
N288_RS08525	COG4839	cell division protein FtsL
N288_RS08530	COG0768	penicillin binding
N288_RS08535	COG0768	penicillin binding
N288_RS08540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N288_RS08545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N288_RS08550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N288_RS08555	COG0772	Belongs to the SEDS family
N288_RS08570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N288_RS08575	COG3879	Bacterial protein of unknown function (DUF881)
N288_RS08580	COG3879	Bacterial protein of unknown function (DUF881)
N288_RS08585	COG3856	small basic protein
N288_RS08590	COG0849	cell division
N288_RS08595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N288_RS08605	COG1191	sigma factor activity
N288_RS08610	COG1191	sigma factor activity
N288_RS08615	COG1873	PFAM PRC-barrel domain
N288_RS08625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N288_RS08630	COG1799	cell septum assembly
N288_RS08635	COG0762	integral membrane protein
N288_RS08640	COG2302	S4 RNA-binding domain
N288_RS08645	COG3599	regulation of cell shape
N288_RS08660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N288_RS08665	COG0564	pseudouridine synthase activity
N288_RS08670	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N288_RS08685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N288_RS08695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N288_RS08700	COG0543	2 iron, 2 sulfur cluster binding
N288_RS08705	COG0167	dihydroorotate dehydrogenase activity
N288_RS08710	COG0284	orotidine-5'-phosphate decarboxylase activity
N288_RS08715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N288_RS08725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N288_RS08730	COG1561	YicC-like family, N-terminal region
N288_RS08740	COG0194	GDP metabolic process
N288_RS08750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N288_RS08755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N288_RS08760	COG0242	peptide deformylase activity
N288_RS08765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N288_RS08770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N288_RS08770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N288_RS08775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N288_RS08780	COG0631	protein serine/threonine phosphatase activity
N288_RS08785	COG0515	serine threonine protein kinase
N288_RS08785	COG2815	serine threonine protein kinase
N288_RS08795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N288_RS08800	COG1564	THIamine pyrophosphokinase
N288_RS08810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N288_RS08815	COG1302	Protein conserved in bacteria
N288_RS08820	COG1461	Dihydroxyacetone kinase
N288_RS08825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N288_RS08830	COG1349	DNA-binding transcription factor activity
N288_RS08835	COG0416	fatty acid biosynthetic process
N288_RS08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N288_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS08850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N288_RS08855	COG0571	ribonuclease III activity
N288_RS08860	COG1196	nuclear chromosome segregation
N288_RS08865	COG0552	protein localization to endoplasmic reticulum
N288_RS08875	COG1131	(ABC) transporter
N288_RS08890	COG0714	Associated with various cellular activities
N288_RS08910	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N288_RS08915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N288_RS08925	COG1837	Belongs to the UPF0109 family
N288_RS08935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N288_RS08940	COG0336	Belongs to the RNA methyltransferase TrmD family
N288_RS08945	COG0335	large ribosomal subunit rRNA binding
N288_RS08975	COG2257	FlhB HrpN YscU SpaS Family
N288_RS08980	COG0045	succinate-CoA ligase (ADP-forming) activity
N288_RS08985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N288_RS08990	COG0758	DNA mediated transformation
N288_RS08995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N288_RS09000	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N288_RS09005	COG4974	Belongs to the 'phage' integrase family
N288_RS09010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N288_RS09015	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N288_RS09020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N288_RS09025	COG1815	bacterial-type flagellum-dependent cell motility
N288_RS09030	COG1558	bacterial-type flagellum-dependent cell motility
N288_RS09035	COG1677	Flagellar hook-basal body complex protein FliE
N288_RS09040	COG1766	The M ring may be actively involved in energy transduction
N288_RS09045	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N288_RS09050	COG1317	bacterial-type flagellum organization
N288_RS09055	COG1157	protein secretion by the type III secretion system
N288_RS09060	COG2882	bacterial-type flagellum organization
N288_RS09075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N288_RS09085	COG4786	Flagellar basal body rod
N288_RS09090	COG1582	Flagellar protein (FlbD)
N288_RS09095	COG1580	Controls the rotational direction of flagella during chemotaxis
N288_RS09100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N288_RS09105	COG1776	CheC inhibitor of MCP methylation
N288_RS09105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N288_RS09110	COG2201	protein-glutamate methylesterase activity
N288_RS09115	COG3190	flagellar
N288_RS09120	COG1338	Plays a role in the flagellum-specific transport system
N288_RS09125	COG1987	bacterial-type flagellum assembly
N288_RS09130	COG1684	flagellar biosynthetic protein fliR
N288_RS09135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N288_RS09140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N288_RS09145	COG1419	protein localization to endoplasmic reticulum
N288_RS09150	COG0455	bacterial-type flagellum organization
N288_RS09155	COG2201	protein-glutamate methylesterase activity
N288_RS09160	COG2198	Histidine kinase
N288_RS09160	COG0643	Histidine kinase
N288_RS09165	COG0835	chemotaxis
N288_RS09170	COG1776	CheC inhibitor of MCP methylation
N288_RS09175	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N288_RS09185	COG1191	sigma factor activity
N288_RS09210	COG0528	UMP kinase activity
N288_RS09215	COG0233	cytoplasmic translational termination
N288_RS09225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N288_RS09230	COG4589	Belongs to the CDS family
N288_RS09235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N288_RS09240	COG0750	zinc metalloprotease
N288_RS09250	COG3547	Transposase (IS116 IS110 IS902 family)
N288_RS09255	COG2176	DNA-directed DNA polymerase activity
N288_RS09260	COG0779	Required for maturation of 30S ribosomal subunits
N288_RS09265	COG0195	Participates in both transcription termination and antitermination
N288_RS09270	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N288_RS09275	COG1358	cellular component organization or biogenesis
N288_RS09285	COG1550	Protein conserved in bacteria
N288_RS09290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N288_RS09295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N288_RS09300	COG0196	riboflavin kinase activity
N288_RS09305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N288_RS09310	COG1185	polyribonucleotide nucleotidyltransferase activity
N288_RS09315	COG0726	polysaccharide deacetylase
N288_RS09320	COG0612	Peptidase, M16
N288_RS09325	COG1873	PFAM PRC-barrel domain
N288_RS09330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N288_RS09335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N288_RS09340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N288_RS09345	COG0527	aspartate kinase activity
N288_RS09355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N288_RS09360	COG0740	serine-type endopeptidase activity
N288_RS09370	COG1674	ftsk spoiiie
N288_RS09370	COG4980	gas vesicle protein
N288_RS09375	COG2188	Transcriptional regulator
N288_RS09380	COG1744	ABC transporter substrate-binding protein PnrA-like
N288_RS09385	COG3845	ABC transporter
N288_RS09390	COG4603	Belongs to the binding-protein-dependent transport system permease family
N288_RS09395	COG1079	Belongs to the binding-protein-dependent transport system permease family
N288_RS09400	COG3706	GGDEF domain
N288_RS09405	COG0612	Peptidase, M16
N288_RS09410	COG0612	Peptidase, M16
N288_RS09415	COG0300	oxidoreductase activity
N288_RS09430	COG1426	Protein conserved in bacteria
N288_RS09435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N288_RS09440	COG1058	Belongs to the CinA family
N288_RS09440	COG1546	Belongs to the CinA family
N288_RS09445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N288_RS09455	COG1692	metallophosphoesterase
N288_RS09460	COG2359	stage V sporulation protein S
N288_RS09470	COG0674	pyruvate-flavodoxin oxidoreductase activity
N288_RS09470	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
N288_RS09475	COG1013	pyruvate-flavodoxin oxidoreductase activity
N288_RS09480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N288_RS09485	COG4550	Control of competence regulator ComK, YlbF/YmcA
N288_RS09495	COG0346	lactoylglutathione lyase activity
N288_RS09500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N288_RS09505	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N288_RS09520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N288_RS09535	COG1077	Cell shape determining protein MreB Mrl
N288_RS09540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N288_RS09545	COG1923	regulation of RNA biosynthetic process
N288_RS09555	COG0464	growth
N288_RS09560	COG2860	membrane
N288_RS09565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N288_RS09570	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N288_RS09575	COG0789	Transcriptional regulator
N288_RS09580	COG0174	glutamine synthetase
N288_RS09610	COG3620	sequence-specific DNA binding
N288_RS09625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N288_RS09630	COG1388	LysM domain
N288_RS09635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N288_RS09640	COG4224	UPF0291 protein
N288_RS09655	COG3763	UPF0154 protein
N288_RS09670	COG1132	(ABC) transporter
N288_RS09675	COG1132	(ABC) transporter
N288_RS09685	COG0785	Cytochrome C biogenesis protein
N288_RS09690	COG2201	protein-glutamate methylesterase activity
N288_RS09695	COG4846	Membrane protein involved in cytochrome C biogenesis
N288_RS09730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS09755	COG0697	spore germination
N288_RS09775	COG1715	Restriction endonuclease
N288_RS09780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N288_RS09790	COG2222	sugar isomerase
N288_RS09795	COG1653	transport
N288_RS09800	COG1175	transmembrane transport
N288_RS09805	COG0395	ABC-type sugar transport system, permease component
N288_RS09810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N288_RS09820	COG3711	transcriptional antiterminator
N288_RS09820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS09825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N288_RS09830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N288_RS09840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N288_RS09845	COG1447	Phosphotransferase system cellobiose-specific component IIA
N288_RS09850	COG1486	melibiose metabolic process
N288_RS09855	COG0583	DNA-binding transcription factor activity
N288_RS09860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N288_RS09865	COG3773	Cell wall hydrolase
N288_RS09870	COG0579	oxidoreductase
N288_RS09875	COG0406	alpha-ribazole phosphatase activity
N288_RS09875	COG0494	nUDIX hydrolase
N288_RS09900	COG0492	ferredoxin-NADP+ reductase activity
N288_RS09905	COG2226	methyltransferase
N288_RS09915	COG0653	protein targeting
N288_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS09950	COG5278	phosphoserine phosphatase activity
N288_RS09950	COG0840	transmembrane signaling receptor activity
N288_RS09955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N288_RS09960	COG1794	racemase activity, acting on amino acids and derivatives
N288_RS09965	COG1132	(ABC) transporter
N288_RS09970	COG2755	lipolytic protein G-D-S-L family
N288_RS09975	COG2207	Transcriptional regulator
N288_RS09980	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N288_RS09990	COG1073	alpha beta
N288_RS09995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N288_RS10005	COG0395	ABC-type sugar transport system, permease component
N288_RS10010	COG4209	transmembrane transport
N288_RS10015	COG5578	integral membrane protein
N288_RS10020	COG1653	transport
N288_RS10025	COG4677	pectinesterase activity
N288_RS10030	COG4677	pectinesterase activity
N288_RS10035	COG0657	acetylesterase activity
N288_RS10035	COG2755	lipolytic protein G-D-S-L family
N288_RS10045	COG0667	Aldo Keto reductase
N288_RS10050	COG1904	glucuronate isomerase
N288_RS10055	COG1609	Transcriptional regulator
N288_RS10060	COG0246	Mannitol dehydrogenase
N288_RS10065	COG2721	sulfolactate sulfo-lyase activity
N288_RS10080	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N288_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS10095	COG2720	vancomycin resistance protein
N288_RS10115	COG1966	Carbon starvation protein
N288_RS10130	COG2814	Major facilitator Superfamily
N288_RS10155	COG0420	3'-5' exonuclease activity
N288_RS10160	COG0419	ATPase involved in DNA repair
N288_RS10175	COG1309	transcriptional regulator
N288_RS10185	COG5522	Integral membrane protein (intg_mem_TP0381)
N288_RS10205	COG5146	pantothenate kinase activity
N288_RS10215	COG2234	aminopeptidase activity
N288_RS10220	COG1388	LysM domain
N288_RS10220	COG0791	NLP P60 protein
N288_RS10225	COG1876	peptidase activity
N288_RS10230	COG1363	Peptidase, m42
N288_RS10235	COG5002	protein histidine kinase activity
N288_RS10240	COG0628	permease
N288_RS10245	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
N288_RS10245	COG3264	Mechanosensitive ion channel
N288_RS10255	COG1388	LysM domain
N288_RS10255	COG0791	NLP P60 protein
N288_RS10275	COG2364	Membrane
N288_RS10280	COG1368	sulfuric ester hydrolase activity
N288_RS10295	COG1595	DNA-templated transcription, initiation
N288_RS10310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N288_RS10325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N288_RS10330	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N288_RS10340	COG1760	l-serine dehydratase
N288_RS10345	COG1760	l-serine dehydratase
N288_RS10355	COG0500	methyltransferase
N288_RS10395	COG0494	nUDIX hydrolase
N288_RS10420	COG2199	diguanylate cyclase activity
N288_RS10435	COG1846	Transcriptional regulator
N288_RS10440	COG0477	Major facilitator Superfamily
N288_RS10450	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
N288_RS10460	COG3973	AAA domain
N288_RS10485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N288_RS10495	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
N288_RS10500	COG3396	Phenylacetate-CoA oxygenase
N288_RS10515	COG2151	metal-sulfur cluster biosynthetic enzyme
N288_RS10525	COG1024	Enoyl-CoA hydratase
N288_RS10530	COG1250	3-hydroxyacyl-CoA dehydrogenase
N288_RS10535	COG0183	Belongs to the thiolase family
N288_RS10540	COG3327	negative regulation of DNA-templated transcription, initiation
N288_RS10545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N288_RS10550	COG2046	Belongs to the sulfate adenylyltransferase family
N288_RS10555	COG0529	Catalyzes the synthesis of activated sulfate
N288_RS10560	COG0471	metal ion transport
N288_RS10560	COG3273	potassium ion transport
N288_RS10570	COG1086	Polysaccharide biosynthesis protein
N288_RS10580	COG1086	Polysaccharide biosynthesis protein
N288_RS10585	COG1216	Glycosyl transferase, family 2
N288_RS10595	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N288_RS10600	COG1091	dTDP-4-dehydrorhamnose reductase activity
N288_RS10605	COG1088	dTDP-glucose 4,6-dehydratase activity
N288_RS10610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N288_RS10645	COG1216	Glycosyl transferase, family 2
N288_RS10665	COG0438	transferase activity, transferring glycosyl groups
N288_RS10670	COG1216	Glycosyl transferase, family 2
N288_RS10710	COG2070	2-Nitropropane dioxygenase
N288_RS10720	COG4120	Belongs to the binding-protein-dependent transport system permease family
N288_RS10725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N288_RS10750	COG0508	dehydrogenase complex catalyzes the overall conversion of
N288_RS10760	COG3185	4-Hydroxyphenylpyruvate dioxygenase
N288_RS10765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N288_RS10770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N288_RS10775	COG0179	Fumarylacetoacetate (FAA) hydrolase
N288_RS10790	COG1307	EDD domain protein, DegV family
N288_RS10800	COG1960	acyl-CoA dehydrogenase activity
N288_RS10805	COG0183	Belongs to the thiolase family
N288_RS10815	COG2323	membrane
N288_RS10820	COG3546	catalase activity
N288_RS10835	COG1054	Belongs to the UPF0176 family
N288_RS10845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N288_RS10855	COG3437	response regulator, receiver
N288_RS10855	COG2770	Histidine kinase
N288_RS10905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N288_RS10910	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N288_RS10920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS10940	COG0464	growth
N288_RS10945	COG0824	Thioesterase
N288_RS10955	COG4841	protein insertion into membrane
N288_RS10965	COG5002	protein histidine kinase activity
N288_RS10970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N288_RS10975	COG0254	rRNA binding
N288_RS11000	COG2233	PERMEase
N288_RS11010	COG1832	CoA-binding protein
N288_RS11015	COG0187	DNA topoisomerase II activity
N288_RS11020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N288_RS11025	COG1115	amino acid carrier protein
N288_RS11050	COG0590	tRNA wobble adenosine to inosine editing
N288_RS11055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N288_RS11075	COG0709	Synthesizes selenophosphate from selenide and ATP
N288_RS11085	COG3639	organic phosphonate transmembrane transporter activity
N288_RS11090	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
N288_RS11100	COG0494	nUDIX hydrolase
N288_RS11105	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
N288_RS11110	COG0415	Belongs to the DNA photolyase family
N288_RS11115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N288_RS11125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N288_RS11145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N288_RS11150	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS11175	COG0493	'glutamate synthase
N288_RS11185	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N288_RS11190	COG1473	amidohydrolase
N288_RS11195	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS11205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N288_RS11210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N288_RS11220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N288_RS11230	COG2027	D-alanyl-D-alanine carboxypeptidase
N288_RS11250	COG1404	Belongs to the peptidase S8 family
N288_RS11260	COG0708	Exodeoxyribonuclease III
N288_RS11265	COG3663	DNA glycosylase
N288_RS11270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N288_RS11275	COG0840	transmembrane signaling receptor activity
N288_RS11280	COG1418	mRNA catabolic process
N288_RS11290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N288_RS11295	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS11300	COG0346	lactoylglutathione lyase activity
N288_RS11310	COG2814	Major facilitator Superfamily
N288_RS11320	COG3858	chitin binding
N288_RS11320	COG1388	LysM domain
N288_RS11340	COG4989	oxidoreductase activity
N288_RS11365	COG1388	LysM domain
N288_RS11365	COG3584	3D domain protein
N288_RS11370	COG1164	Oligoendopeptidase f
N288_RS11395	COG3361	conserved protein (COG2071)
N288_RS11420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N288_RS11425	COG1193	negative regulation of DNA recombination
N288_RS11430	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS11435	COG1999	signal sequence binding
N288_RS11440	COG0488	(ABC) transporter
N288_RS11450	COG1686	Belongs to the peptidase S11 family
N288_RS11460	COG2404	hydrolase activity, acting on ester bonds
N288_RS11470	COG2340	Cysteine-rich secretory protein family
N288_RS11485	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N288_RS11490	COG1335	isochorismatase
N288_RS11500	COG1268	BioY protein
N288_RS11505	COG0392	lysyltransferase activity
N288_RS11505	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N288_RS11540	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N288_RS11540	COG2105	PFAM AIG2 family protein
N288_RS11545	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS11555	COG0432	Pfam Uncharacterised protein family UPF0047
N288_RS11565	COG2746	aminoglycoside 3-N-acetyltransferase activity
N288_RS11575	COG0508	dehydrogenase complex catalyzes the overall conversion of
N288_RS11580	COG0567	Dehydrogenase, E1 component
N288_RS11595	COG0626	cystathionine gamma-synthase activity
N288_RS11600	COG0626	cystathionine gamma-synthase activity
N288_RS11605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N288_RS11605	COG0646	methionine synthase
N288_RS11610	COG1410	methionine synthase
N288_RS11610	COG0646	methionine synthase
N288_RS11620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N288_RS11625	COG1984	allophanate hydrolase subunit 2
N288_RS11630	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N288_RS11655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N288_RS11665	COG1253	flavin adenine dinucleotide binding
N288_RS11670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS11675	COG1834	amidinotransferase
N288_RS11685	COG0628	permease
N288_RS11710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N288_RS11715	COG1966	Carbon starvation protein
N288_RS11735	COG1268	BioY protein
N288_RS11750	COG0726	polysaccharide deacetylase
N288_RS11770	COG0697	spore germination
N288_RS11775	COG1960	acyl-CoA dehydrogenase activity
N288_RS11795	COG0640	Transcriptional regulator
N288_RS11805	COG1664	Polymer-forming cytoskeletal
N288_RS11815	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS11830	COG1607	acyl-coa hydrolase
N288_RS11840	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
N288_RS11900	COG0463	Glycosyl transferase, family 2
N288_RS11910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N288_RS11915	COG0534	Mate efflux family protein
N288_RS11930	COG3226	Transcriptional regulator
N288_RS11950	COG0697	spore germination
N288_RS11955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N288_RS11965	COG0242	peptide deformylase activity
N288_RS11970	COG5002	protein histidine kinase activity
N288_RS11980	COG0702	epimerase
N288_RS11990	COG0720	synthase
N288_RS12000	COG0561	phosphatase activity
N288_RS12005	COG0204	Acyl-transferase
N288_RS12030	COG1595	DNA-templated transcription, initiation
N288_RS12035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS12050	COG0456	acetyltransferase
N288_RS12055	COG1764	response to oxidative stress
N288_RS12060	COG0024	Methionine aminopeptidase
N288_RS12070	COG1733	regulation of RNA biosynthetic process
N288_RS12075	COG2514	catechol 2,3-dioxygenase activity
N288_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS12095	COG0753	catalase activity
N288_RS12130	COG0352	thiamine-phosphate diphosphorylase activity
N288_RS12135	COG0351	phosphomethylpyrimidine kinase
N288_RS12145	COG5002	protein histidine kinase activity
N288_RS12150	COG0745	RESPONSE REGULATOR receiver
N288_RS12160	COG4990	cell redox homeostasis
N288_RS12170	COG2124	cytochrome p450
N288_RS12195	COG1595	DNA-templated transcription, initiation
N288_RS12220	COG1113	amino acid transport
N288_RS12235	COG0385	Bile acid
N288_RS12245	COG1272	protein, Hemolysin III
N288_RS12255	COG0697	spore germination
N288_RS12260	COG3403	YqcI/YcgG family
N288_RS12280	COG1959	2 iron, 2 sulfur cluster binding
N288_RS12300	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N288_RS12305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N288_RS12315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N288_RS12320	COG0529	Catalyzes the synthesis of activated sulfate
N288_RS12325	COG2046	Belongs to the sulfate adenylyltransferase family
N288_RS12330	COG0306	phosphate transporter
N288_RS12360	COG0714	Associated with various cellular activities
N288_RS12385	COG0768	penicillin binding
N288_RS12395	COG1595	DNA-templated transcription, initiation
N288_RS12400	COG2197	response regulator
N288_RS12405	COG4585	Histidine kinase
N288_RS12410	COG3239	Fatty acid desaturase
N288_RS12440	COG4166	transmembrane transport
N288_RS12460	COG2205	protein histidine kinase activity
N288_RS12485	COG3559	Exporter of polyketide antibiotics
N288_RS12490	COG1131	(ABC) transporter
N288_RS12495	COG1309	transcriptional regulator
N288_RS12525	COG0628	permease
N288_RS12530	COG1253	flavin adenine dinucleotide binding
N288_RS12550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N288_RS12555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N288_RS12560	COG0431	NADPH-dependent FMN reductase
N288_RS12570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N288_RS12600	COG3878	Protein conserved in bacteria
N288_RS12615	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS12625	COG1309	transcriptional regulator
N288_RS12645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS12665	COG0561	phosphatase activity
N288_RS12675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N288_RS12680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N288_RS12685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N288_RS12690	COG0438	transferase activity, transferring glycosyl groups
N288_RS12760	COG3708	Transcriptional regulator
N288_RS12760	COG2207	Transcriptional regulator
N288_RS12790	COG1132	(ABC) transporter
N288_RS12800	COG1846	Transcriptional regulator
N288_RS12805	COG3852	Histidine kinase
N288_RS12855	COG1114	Component of the transport system for branched-chain amino acids
N288_RS12860	COG1802	Transcriptional regulator
N288_RS12870	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS12875	COG1454	alcohol dehydrogenase
N288_RS12880	COG0655	NAD(P)H dehydrogenase (quinone) activity
N288_RS12905	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS12905	COG2202	Pas domain
N288_RS12930	COG1393	Belongs to the ArsC family
N288_RS12970	COG1476	TRANSCRIPTIONal
N288_RS12975	COG3655	Transcriptional regulator
N288_RS12990	COG0456	acetyltransferase
N288_RS13000	COG0494	nUDIX hydrolase
N288_RS13025	COG1595	DNA-templated transcription, initiation
N288_RS13075	COG1368	sulfuric ester hydrolase activity
N288_RS13080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N288_RS13090	COG0406	alpha-ribazole phosphatase activity
N288_RS13115	COG2814	Major facilitator Superfamily
N288_RS13125	COG2323	membrane
N288_RS13135	COG0667	Aldo Keto reductase
N288_RS13150	COG0395	ABC-type sugar transport system, permease component
N288_RS13155	COG1175	transmembrane transport
N288_RS13160	COG1653	transport
N288_RS13165	COG2723	6-phospho-beta-galactosidase activity
N288_RS13170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS13175	COG0400	carboxylic ester hydrolase activity
N288_RS13180	COG1357	PFAM Pentapeptide repeats (8 copies)
N288_RS13190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N288_RS13255	COG1164	Oligoendopeptidase f
N288_RS13280	COG1368	sulfuric ester hydrolase activity
N288_RS13300	COG1476	TRANSCRIPTIONal
N288_RS13330	COG0523	cobalamin synthesis protein
N288_RS13340	COG0701	Predicted permease
N288_RS13345	COG3689	TIGRFAM TIGR03943 family protein
N288_RS13385	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS13390	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS13415	COG2226	methyltransferase
N288_RS13450	COG0860	N-Acetylmuramoyl-L-alanine amidase
N288_RS13455	COG0697	spore germination
N288_RS13460	COG0577	efflux transmembrane transporter activity
N288_RS13465	COG1136	(ABC) transporter
N288_RS13470	COG2205	protein histidine kinase activity
N288_RS13475	COG0745	RESPONSE REGULATOR receiver
N288_RS13490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS13495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N288_RS13505	COG0124	histidyl-tRNA synthetase
N288_RS13515	COG0753	catalase activity
N288_RS13525	COG3708	Transcriptional regulator
N288_RS13525	COG2207	Transcriptional regulator
N288_RS13530	COG0747	negative chemotaxis
N288_RS13535	COG0747	negative chemotaxis
N288_RS13540	COG1595	DNA-templated transcription, initiation
N288_RS13545	COG5002	protein histidine kinase activity
N288_RS13565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N288_RS13570	COG0501	Belongs to the peptidase M48B family
N288_RS13580	COG5002	protein histidine kinase activity
N288_RS13585	COG0745	RESPONSE REGULATOR receiver
N288_RS13600	COG0840	transmembrane signaling receptor activity
N288_RS13605	COG1088	dTDP-glucose 4,6-dehydratase activity
N288_RS13615	COG2267	carboxylic ester hydrolase activity
N288_RS13620	COG3679	Belongs to the UPF0342 family
N288_RS13650	COG1595	DNA-templated transcription, initiation
N288_RS13660	COG1476	TRANSCRIPTIONal
N288_RS13670	COG3340	Belongs to the peptidase S51 family
N288_RS13690	COG0534	Mate efflux family protein
N288_RS13705	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS13720	COG2233	PERMEase
N288_RS13730	COG0586	Pfam SNARE associated Golgi protein
N288_RS13740	COG3546	catalase activity
N288_RS13795	COG0477	Major facilitator Superfamily
N288_RS13800	COG1309	transcriptional regulator
N288_RS13805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS13820	COG0405	Gamma-glutamyltransferase
N288_RS13830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N288_RS13845	COG3181	Tripartite tricarboxylate transporter family receptor
N288_RS13850	COG4565	transcriptional regulatory protein
N288_RS13855	COG3290	protein histidine kinase activity
N288_RS13865	COG4572	Cation transport regulator
N288_RS13870	COG1346	cytolysis
N288_RS13875	COG1380	Effector of murein hydrolase LrgA
N288_RS13880	COG2814	Major facilitator Superfamily
N288_RS13885	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS13915	COG0673	inositol 2-dehydrogenase activity
N288_RS13930	COG1408	metallophosphoesterase
N288_RS13955	COG1247	-acetyltransferase
N288_RS13965	COG1595	DNA-templated transcription, initiation
N288_RS13970	COG0322	excinuclease ABC activity
N288_RS13980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N288_RS14000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N288_RS14010	COG5002	protein histidine kinase activity
N288_RS14020	COG0628	permease
N288_RS14030	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS14045	COG0384	phenazine biosynthesis protein PhzF
N288_RS14055	COG4149	molybdate abc transporter
N288_RS14060	COG0778	Nitroreductase
N288_RS14080	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N288_RS14090	COG0071	Belongs to the small heat shock protein (HSP20) family
N288_RS14110	COG0640	Transcriptional regulator
N288_RS14135	COG1253	flavin adenine dinucleotide binding
N288_RS14145	COG0840	transmembrane signaling receptor activity
N288_RS14150	COG0791	NLP P60 protein
N288_RS14150	COG3883	PFAM NLP P60 protein
N288_RS14170	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N288_RS14190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N288_RS14210	COG2217	Heavy metal translocating P-type atpase
N288_RS14215	COG2608	mercury ion transmembrane transporter activity
N288_RS14240	COG1902	pentaerythritol trinitrate reductase activity
N288_RS14245	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N288_RS14255	COG1263	PTS System
N288_RS14255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N288_RS14270	COG0730	response to heat
N288_RS14280	COG4166	transmembrane transport
N288_RS14285	COG4608	Belongs to the ABC transporter superfamily
N288_RS14290	COG0444	Belongs to the ABC transporter superfamily
N288_RS14295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N288_RS14300	COG0601	transmembrane transport
N288_RS14305	COG2362	D-Aminopeptidase
N288_RS14310	COG1363	Peptidase, m42
N288_RS14315	COG1522	sequence-specific DNA binding
N288_RS14320	COG1228	amidohydrolase
N288_RS14325	COG2223	nitrite transmembrane transporter activity
N288_RS14330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N288_RS14335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N288_RS14340	COG1764	response to oxidative stress
N288_RS14345	COG0561	phosphatase activity
N288_RS14350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N288_RS14355	COG0471	metal ion transport
N288_RS14360	COG1737	Transcriptional regulator
N288_RS14370	COG0789	Transcriptional regulator
N288_RS14380	COG0456	acetyltransferase
N288_RS14385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N288_RS14385	COG3153	acetyltransferase
N288_RS14390	COG3300	MHYT domain
N288_RS14390	COG5001	Diguanylate cyclase
N288_RS14395	COG1132	(ABC) transporter
N288_RS14415	COG2135	peptidase activity
N288_RS14420	COG3546	catalase activity
N288_RS14430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N288_RS14435	COG2226	methyltransferase
N288_RS14475	COG0134	indole-3-glycerol-phosphate synthase activity
N288_RS14485	COG0512	Glutamine amidotransferase of anthranilate synthase
N288_RS14500	COG2258	MOSC domain
N288_RS14505	COG2814	Major facilitator Superfamily
N288_RS14510	COG0840	transmembrane signaling receptor activity
N288_RS14515	COG0596	Alpha beta hydrolase
N288_RS14540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N288_RS14540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS14540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N288_RS14545	COG1105	Belongs to the carbohydrate kinase PfkB family
N288_RS14550	COG1349	DNA-binding transcription factor activity
N288_RS14560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N288_RS14565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N288_RS14570	COG3314	Sporulation integral membrane protein YlbJ
N288_RS14575	COG0010	Belongs to the arginase family
N288_RS14580	COG1228	amidohydrolase
N288_RS14585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
N288_RS14595	COG4129	membrane
N288_RS14620	COG2814	Major facilitator Superfamily
N288_RS14625	COG0745	RESPONSE REGULATOR receiver
N288_RS14630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N288_RS14635	COG2205	protein histidine kinase activity
N288_RS14635	COG0784	Response regulator, receiver
N288_RS14645	COG2239	Acts as a magnesium transporter
N288_RS14650	COG1280	lysine exporter protein (LysE YggA)
N288_RS14670	COG2755	lipolytic protein G-D-S-L family
N288_RS14675	COG3852	Histidine kinase
N288_RS14715	COG0513	Belongs to the DEAD box helicase family
N288_RS14725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N288_RS14735	COG0671	phosphoesterase, PA-phosphatase related
N288_RS14740	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N288_RS14745	COG3285	dna ligase
N288_RS14745	COG1793	dna ligase
N288_RS14750	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N288_RS14760	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N288_RS14770	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N288_RS14775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N288_RS14775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N288_RS14780	COG0307	riboflavin synthase, alpha
N288_RS14785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N288_RS14785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N288_RS14790	COG2217	Heavy metal translocating P-type atpase
N288_RS14795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS14810	COG4667	esterase of the alpha-beta hydrolase superfamily
N288_RS14825	COG0586	Pfam SNARE associated Golgi protein
N288_RS14850	COG0668	transmembrane transport
N288_RS14855	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
N288_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS14880	COG2340	Cysteine-rich secretory protein family
N288_RS14885	COG2205	protein histidine kinase activity
N288_RS14890	COG0745	RESPONSE REGULATOR receiver
N288_RS14915	COG1846	Transcriptional regulator
N288_RS14920	COG0523	cobalamin synthesis protein
N288_RS14930	COG0793	Belongs to the peptidase S41A family
N288_RS14930	COG3409	Peptidoglycan-binding domain 1 protein
N288_RS14940	COG1876	peptidase activity
N288_RS14960	COG4326	sporulation control protein
N288_RS14975	COG4479	Belongs to the UPF0346 family
N288_RS14985	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
N288_RS15000	COG1509	lysine 2,3-aminomutase activity
N288_RS15005	COG3829	transcription factor binding
N288_RS15010	COG0456	acetyltransferase
N288_RS15015	COG1012	belongs to the aldehyde dehydrogenase family
N288_RS15020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N288_RS15025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N288_RS15030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N288_RS15035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N288_RS15050	COG0840	transmembrane signaling receptor activity
N288_RS15050	COG5278	phosphoserine phosphatase activity
N288_RS15070	COG2190	(PTS) system
N288_RS15075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N288_RS15100	COG2755	lipolytic protein G-D-S-L family
N288_RS15105	COG1999	signal sequence binding
N288_RS15130	COG1307	EDD domain protein, DegV family
N288_RS15145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N288_RS15155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N288_RS15170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N288_RS15180	COG2310	stress, protein
N288_RS15185	COG2310	stress, protein
N288_RS15190	COG3853	Toxic anion resistance protein (TelA)
N288_RS15225	COG0861	Integral membrane protein TerC family
N288_RS15230	COG2310	stress, protein
N288_RS15240	COG0436	Aminotransferase
N288_RS15245	COG2521	methyltransferase
N288_RS15245	COG2136	Putative SAM-dependent methyltransferase
N288_RS15255	COG0129	dihydroxy-acid dehydratase activity
N288_RS15260	COG1413	lyase activity
N288_RS15265	COG0488	(ABC) transporter
N288_RS15270	COG1418	mRNA catabolic process
N288_RS15275	COG1307	EDD domain protein, DegV family
N288_RS15290	COG0386	Belongs to the glutathione peroxidase family
N288_RS15325	COG1321	iron dependent repressor
N288_RS15330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N288_RS15335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N288_RS15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N288_RS15340	COG1321	iron dependent repressor
N288_RS15345	COG1121	(ABC) transporter
N288_RS15350	COG0803	Belongs to the bacterial solute-binding protein 9 family
N288_RS15365	COG1278	Cold shock
N288_RS15370	COG0328	RNA-DNA hybrid ribonuclease activity
N288_RS15375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N288_RS15380	COG0328	RNA-DNA hybrid ribonuclease activity
N288_RS15395	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N288_RS15405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N288_RS15425	COG3541	Predicted nucleotidyltransferase
N288_RS15430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N288_RS15435	COG1755	Isoprenylcysteine carboxyl methyltransferase
N288_RS15440	COG3424	synthase
N288_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS15470	COG2233	PERMEase
N288_RS15485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N288_RS15490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N288_RS15500	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N288_RS15505	COG1199	ATP-dependent helicase activity
N288_RS15510	COG0116	Belongs to the methyltransferase superfamily
N288_RS15530	COG4474	Belongs to the UPF0398 family
N288_RS15540	COG3359	exonuclease
N288_RS15545	COG1205	dead DEAH box helicase
N288_RS15545	COG1111	helicase
N288_RS15570	COG0601	transmembrane transport
N288_RS15600	COG3331	DNA recombination
N288_RS15605	COG4499	WXG100 protein secretion system (Wss), protein YukC
N288_RS15605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N288_RS15615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N288_RS15620	COG3935	DnaD domain protein
N288_RS15640	COG1199	ATP-dependent helicase activity
N288_RS15640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N288_RS15650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N288_RS15655	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N288_RS15675	COG0617	tRNA 3'-terminal CCA addition
N288_RS15680	COG0438	transferase activity, transferring glycosyl groups
N288_RS15685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N288_RS15690	COG1803	Methylglyoxal synthase
N288_RS15695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N288_RS15700	COG1694	Mazg nucleotide pyrophosphohydrolase
N288_RS15705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS15710	COG2738	Putative neutral zinc metallopeptidase
N288_RS15720	COG4347	Protein of unknown function (DUF1405)
N288_RS15730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N288_RS15745	COG5582	Belongs to the UPF0302 family
N288_RS15750	COG0457	Tetratricopeptide repeat
N288_RS15760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N288_RS15765	COG0287	Prephenate dehydrogenase
N288_RS15770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N288_RS15775	COG4401	Chorismate mutase type I
N288_RS15780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N288_RS15785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N288_RS15790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N288_RS15795	COG0105	UTP biosynthetic process
N288_RS15800	COG0142	geranyltranstransferase activity
N288_RS15805	COG2226	methyltransferase
N288_RS15810	COG0142	geranyltranstransferase activity
N288_RS15820	COG0302	gtp cyclohydrolase
N288_RS15825	COG0776	regulation of translation
N288_RS15830	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N288_RS15845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N288_RS15870	COG1304	FMN binding
N288_RS15875	COG0539	negative regulation of cytoplasmic translation
N288_RS15880	COG0204	Acyl-transferase
N288_RS15885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N288_RS15900	COG2959	enzyme of heme biosynthesis
N288_RS15905	COG3773	Cell wall hydrolase
N288_RS15905	COG3409	Peptidoglycan-binding domain 1 protein
N288_RS15910	COG2339	peptidase activity
N288_RS15920	COG0492	ferredoxin-NADP+ reductase activity
N288_RS15925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N288_RS15930	COG4862	establishment of competence for transformation
N288_RS15940	COG1408	metallophosphoesterase
N288_RS15960	COG1388	LysM domain
N288_RS15965	COG1266	CAAX protease self-immunity
N288_RS15970	COG0514	ATP-dependent DNA helicase (RecQ)
N288_RS15975	COG4955	Helix-turn-helix domain
N288_RS15980	COG1141	Ferredoxin
N288_RS15985	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N288_RS15990	COG0693	protein deglycase activity
N288_RS15995	COG0789	Transcriptional regulator
N288_RS16005	COG0733	neurotransmitter:sodium symporter activity
N288_RS16010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N288_RS16015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N288_RS16020	COG0739	heme binding
N288_RS16030	COG1595	DNA-templated transcription, initiation
N288_RS16035	COG5002	protein histidine kinase activity
N288_RS16040	COG0745	RESPONSE REGULATOR receiver
N288_RS16045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N288_RS16050	COG1333	cytochrome c biogenesis protein
N288_RS16055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS16060	COG1187	pseudouridine synthase activity
N288_RS16065	COG0700	Nucleoside recognition
N288_RS16070	COG2715	membrane protein required for spore maturation
N288_RS16075	COG1686	Belongs to the peptidase S11 family
N288_RS16080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N288_RS16095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N288_RS16100	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N288_RS16105	COG1547	Domain of unknown function (DUF309)
N288_RS16115	COG4086	secreted protein
N288_RS16125	COG0697	spore germination
N288_RS16150	COG2172	sigma factor antagonist activity
N288_RS16160	COG1686	Belongs to the peptidase S11 family
N288_RS16180	COG4974	Belongs to the 'phage' integrase family
N288_RS16195	COG0735	belongs to the Fur family
N288_RS16200	COG1300	Membrane
N288_RS16210	COG1379	DNA repair
N288_RS16220	COG0667	Aldo Keto reductase
N288_RS16225	COG0456	acetyltransferase
N288_RS16225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N288_RS16245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N288_RS16255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N288_RS16260	COG1073	alpha beta
N288_RS16285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N288_RS16295	COG0300	oxidoreductase activity
N288_RS16300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N288_RS16305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N288_RS16310	COG1216	Glycosyl transferase, family 2
N288_RS16315	COG1902	pentaerythritol trinitrate reductase activity
N288_RS16325	COG1234	tRNA 3'-trailer cleavage
N288_RS16330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N288_RS16335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N288_RS16340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N288_RS16350	COG2195	Cleaves the N-terminal amino acid of tripeptides
N288_RS16355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N288_RS16360	COG0346	lactoylglutathione lyase activity
N288_RS16365	COG1376	ErfK ybiS ycfS ynhG family protein
N288_RS16370	COG4129	membrane
N288_RS16375	COG1126	abc transporter atp-binding protein
N288_RS16380	COG0765	amino acid transport
N288_RS16385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N288_RS16395	COG1703	isobutyryl-CoA mutase activity
N288_RS16400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N288_RS16400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N288_RS16405	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N288_RS16410	COG0508	dehydrogenase complex catalyzes the overall conversion of
N288_RS16415	COG0022	dehydrogenase e1 component
N288_RS16420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N288_RS16425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N288_RS16430	COG3426	butyrate kinase activity
N288_RS16440	COG0280	phosphate acetyltransferase
N288_RS16445	COG3829	transcription factor binding
N288_RS16445	COG3290	protein histidine kinase activity
N288_RS16460	COG0745	RESPONSE REGULATOR receiver
N288_RS16465	COG0750	zinc metalloprotease
N288_RS16470	COG0497	DNA recombination
N288_RS16475	COG1438	arginine binding
N288_RS16480	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N288_RS16485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N288_RS16500	COG1722	exodeoxyribonuclease VII activity
N288_RS16505	COG1570	exodeoxyribonuclease VII activity
N288_RS16510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N288_RS16515	COG1302	Protein conserved in bacteria
N288_RS16520	COG0439	Biotin carboxylase
N288_RS16525	COG0511	ligase activity, forming carbon-carbon bonds
N288_RS16530	COG5278	phosphoserine phosphatase activity
N288_RS16530	COG0840	transmembrane signaling receptor activity
N288_RS16570	COG3854	ATPases associated with a variety of cellular activities
N288_RS16580	COG2968	Membrane
N288_RS16585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N288_RS16590	COG0006	proline dipeptidase activity
N288_RS16595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N288_RS16605	COG3872	metal-dependent enzyme
N288_RS16615	COG1752	Esterase of the alpha-beta hydrolase superfamily
N288_RS16625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N288_RS16630	COG0095	Lipoate-protein ligase
N288_RS16635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N288_RS16640	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N288_RS16645	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N288_RS16650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N288_RS16660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N288_RS16680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N288_RS16705	COG4537	Required for transformation and DNA binding
N288_RS16710	COG1459	type II secretion system
N288_RS16715	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N288_RS16725	COG1393	Belongs to the ArsC family
N288_RS16745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N288_RS16760	COG0011	TIGRFAM Protein of
N288_RS16775	COG1368	sulfuric ester hydrolase activity
N288_RS16780	COG1940	carbohydrate kinase activity
N288_RS16790	COG0697	spore germination
N288_RS16795	COG0457	Tetratricopeptide repeat
N288_RS16795	COG0705	Rhomboid family
N288_RS16810	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N288_RS16815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N288_RS16825	COG0438	transferase activity, transferring glycosyl groups
N288_RS16845	COG0704	Plays a role in the regulation of phosphate uptake
N288_RS16850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N288_RS16855	COG0581	inorganic phosphate transmembrane transporter activity
N288_RS16860	COG0573	inorganic phosphate transmembrane transporter activity
N288_RS16865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N288_RS16870	COG0768	penicillin binding
N288_RS16875	COG0477	Major facilitator Superfamily
N288_RS16885	COG2839	Protein conserved in bacteria
N288_RS16890	COG1283	sodium-dependent phosphate transmembrane transporter activity
N288_RS16895	COG5521	maltodextrose utilization protein MalA
N288_RS16900	COG0840	transmembrane signaling receptor activity
N288_RS16915	COG4709	membrane
N288_RS16920	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N288_RS16925	COG0735	belongs to the Fur family
N288_RS16930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N288_RS16935	COG1121	(ABC) transporter
N288_RS16945	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N288_RS16950	COG0513	Belongs to the DEAD box helicase family
N288_RS16960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N288_RS16965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N288_RS16970	COG2384	SAM-dependent methyltransferase
N288_RS16975	COG2010	Cytochrome c
N288_RS16980	COG1960	acyl-CoA dehydrogenase activity
N288_RS16990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N288_RS16995	COG0358	DNA primase activity
N288_RS17000	COG1671	Belongs to the UPF0178 family
N288_RS17005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N288_RS17010	COG0517	IMP dehydrogenase activity
N288_RS17015	COG0751	glycine-tRNA ligase activity
N288_RS17025	COG1381	Involved in DNA repair and RecF pathway recombination
N288_RS17030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N288_RS17035	COG0295	cytidine deaminase activity
N288_RS17040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N288_RS17045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N288_RS17050	COG1480	7TM receptor with intracellular HD hydrolase
N288_RS17055	COG1702	phosphate starvation-inducible protein PhoH
N288_RS17075	COG4864	UPF0365 protein
N288_RS17080	COG1030	water channel activity
N288_RS17085	COG1610	YqeY-like protein
N288_RS17095	COG1283	sodium-dependent phosphate transmembrane transporter activity
N288_RS17100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N288_RS17105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N288_RS17110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N288_RS17115	COG2264	protein methyltransferase activity
N288_RS17125	COG0443	Heat shock 70 kDa protein
N288_RS17130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N288_RS17135	COG1420	regulation of RNA biosynthetic process
N288_RS17140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N288_RS17145	COG0481	GTPase activity
N288_RS17155	COG0860	N-Acetylmuramoyl-L-alanine amidase
N288_RS17165	COG0268	Binds directly to 16S ribosomal RNA
N288_RS17170	COG1466	dna polymerase III delta subunit
N288_RS17180	COG2333	competence protein COMEC
N288_RS17180	COG0658	competence protein
N288_RS17185	COG2131	deaminase
N288_RS17195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N288_RS17200	COG2226	methyltransferase
N288_RS17205	COG0799	negative regulation of ribosome biogenesis
N288_RS17210	COG1713	HD superfamily hydrolase involved in NAD metabolism
N288_RS17215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N288_RS17220	COG1534	Rna-binding protein
N288_RS17225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N288_RS17230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N288_RS17235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N288_RS17245	COG0688	phosphatidylethanolamine metabolic process
N288_RS17250	COG1183	phosphatidylcholine synthase activity
N288_RS17255	COG1164	Oligoendopeptidase f
N288_RS17280	COG0626	cystathionine gamma-synthase activity
N288_RS17285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N288_RS17290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N288_RS17295	COG2226	methyltransferase
N288_RS17310	COG0768	penicillin binding
N288_RS17315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N288_RS17320	COG0572	uridine kinase
N288_RS17325	COG0826	peptidase U32
N288_RS17330	COG0826	peptidase U32
N288_RS17335	COG4122	O-methyltransferase activity
N288_RS17340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N288_RS17345	COG3906	Belongs to the UPF0473 family
N288_RS17355	COG4472	Bacterial protein of unknown function (DUF965)
N288_RS17360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N288_RS17365	COG0628	permease
N288_RS17380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N288_RS17390	COG0482	sulfurtransferase activity
N288_RS17395	COG1104	cysteine desulfurase activity
N288_RS17400	COG1959	2 iron, 2 sulfur cluster binding
N288_RS17405	COG2364	Membrane
N288_RS17410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N288_RS17420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N288_RS17425	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
N288_RS17430	COG0124	histidyl-tRNA synthetase
N288_RS17440	COG0860	N-Acetylmuramoyl-L-alanine amidase
N288_RS17440	COG3103	Sh3 type 3 domain protein
N288_RS17440	COG4991	sh3 domain protein
N288_RS17445	COG1490	D-aminoacyl-tRNA deacylase activity
N288_RS17450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N288_RS17455	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N288_RS17460	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N288_RS17460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N288_RS17465	COG5416	Lipopolysaccharide assembly protein A domain
N288_RS17470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N288_RS17475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N288_RS17475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N288_RS17485	COG2244	polysaccharide biosynthetic process
N288_RS17490	COG2323	membrane
N288_RS17500	COG1862	Preprotein translocase
N288_RS17510	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N288_RS17515	COG2255	four-way junction helicase activity
N288_RS17545	COG1388	LysM domain
N288_RS17550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N288_RS17555	COG0157	Belongs to the NadC ModD family
N288_RS17560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N288_RS17565	COG1104	cysteine desulfurase activity
N288_RS17570	COG1827	regulation of RNA biosynthetic process
N288_RS17575	COG0077	Prephenate dehydratase
N288_RS17580	COG4492	Belongs to the UPF0735 family
N288_RS17585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N288_RS17590	COG3290	protein histidine kinase activity
N288_RS17600	COG2868	ribosomal protein
N288_RS17605	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N288_RS17615	COG1994	Peptidase M50
N288_RS17620	COG0739	heme binding
N288_RS17625	COG2894	cell division
N288_RS17630	COG0850	regulation of cytokinetic process
N288_RS17645	COG1792	Involved in formation and maintenance of cell shape
N288_RS17650	COG1077	Cell shape determining protein MreB Mrl
N288_RS17655	COG2003	Belongs to the UPF0758 family
N288_RS17660	COG0424	maF-like protein
N288_RS17690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N288_RS17700	COG1459	type II secretion system
N288_RS17710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N288_RS17755	COG0285	dihydrofolate synthase activity
N288_RS17760	COG0525	valine-tRNA ligase activity
N288_RS17770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N288_RS17775	COG1388	LysM domain
N288_RS17780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N288_RS17785	COG0113	porphobilinogen synthase activity
N288_RS17800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N288_RS17815	COG1126	abc transporter atp-binding protein
N288_RS17820	COG0765	amino acid transport
N288_RS17825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N288_RS17835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N288_RS17840	COG0470	DNA polymerase III
N288_RS17840	COG1067	ATP-dependent peptidase activity
N288_RS17845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N288_RS17850	COG0544	peptidyl-prolyl cis-trans isomerase activity
N288_RS17855	COG0457	Tetratricopeptide repeat
N288_RS17855	COG1477	protein flavinylation
N288_RS17860	COG0066	3-isopropylmalate dehydratase activity
N288_RS17865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N288_RS17870	COG0473	3-isopropylmalate dehydrogenase activity
N288_RS17875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N288_RS17880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N288_RS17885	COG0440	acetolactate synthase activity
N288_RS17890	COG0028	Belongs to the TPP enzyme family
N288_RS17895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N288_RS17905	COG0622	Phosphoesterase
N288_RS17910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N288_RS17920	COG5401	PFAM Sporulation and spore germination
N288_RS17925	COG0514	ATP-dependent DNA helicase (RecQ)
N288_RS17930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N288_RS17935	COG1846	Transcriptional regulator
N288_RS17940	COG2197	response regulator
N288_RS17945	COG0824	Thioesterase
N288_RS17950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N288_RS17955	COG1053	succinate dehydrogenase
N288_RS17960	COG2009	succinate dehydrogenase
N288_RS17965	COG1719	4-vinyl reductase, 4VR
N288_RS17975	COG0322	excinuclease ABC activity
N288_RS17980	COG3118	belongs to the thioredoxin family
N288_RS17985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N288_RS17990	COG2086	electron transfer activity
N288_RS17995	COG1024	Enoyl-CoA hydratase
N288_RS18000	COG1309	transcriptional regulator
N288_RS18005	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS18010	COG3766	membrane
N288_RS18020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N288_RS18020	COG1796	DNA polymerase
N288_RS18025	COG1286	toxin biosynthetic process
N288_RS18030	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N288_RS18035	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N288_RS18040	COG0072	phenylalanine-tRNA ligase activity
N288_RS18040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N288_RS18045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N288_RS18050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N288_RS18060	COG1363	Peptidase, m42
N288_RS18080	COG3326	Membrane
N288_RS18085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N288_RS18095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N288_RS18100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N288_RS18110	COG1484	DNA-dependent DNA replication
N288_RS18115	COG3611	Membrane attachment protein
N288_RS18120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N288_RS18130	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N288_RS18135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N288_RS18140	COG0237	dephospho-CoA kinase activity
N288_RS18145	COG1971	Probably functions as a manganese efflux pump
N288_RS18150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N288_RS18155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N288_RS18155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N288_RS18160	COG0330	HflC and HflK could
N288_RS18165	COG0330	HflC and HflK could
N288_RS18170	COG5002	protein histidine kinase activity
N288_RS18175	COG0745	RESPONSE REGULATOR receiver
N288_RS18185	COG0039	L-malate dehydrogenase activity
N288_RS18190	COG0538	isocitrate dehydrogenase activity
N288_RS18195	COG0372	Belongs to the citrate synthase family
N288_RS18200	COG2707	UPF0756 membrane protein
N288_RS18205	COG0628	permease
N288_RS18210	COG3030	protein affecting phage T7 exclusion by the F plasmid
N288_RS18225	COG0825	malonyl-CoA metabolic process
N288_RS18235	COG2186	Transcriptional regulator
N288_RS18240	COG0281	malic enzyme
N288_RS18245	COG0587	DNA-directed DNA polymerase activity
N288_RS18260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N288_RS18270	COG4109	DRTGG domain
N288_RS18280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N288_RS18285	COG0006	proline dipeptidase activity
N288_RS18305	COG0589	response to stress
N288_RS18310	COG0165	Argininosuccinate lyase
N288_RS18315	COG0137	argininosuccinate synthase activity
N288_RS18325	COG0521	Mo-molybdopterin cofactor biosynthetic process
N288_RS18335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N288_RS18340	COG0827	DNA restriction-modification system
N288_RS18345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N288_RS18350	COG3874	Sporulation protein YtfJ
N288_RS18360	COG1714	RDD family
N288_RS18365	COG0616	signal peptide processing
N288_RS18370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N288_RS18375	COG2962	Rard protein
N288_RS18380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
N288_RS18385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N288_RS18395	COG0301	tRNA thio-modification
N288_RS18400	COG1104	cysteine desulfurase activity
N288_RS18405	COG1114	Component of the transport system for branched-chain amino acids
N288_RS18410	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N288_RS18415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N288_RS18420	COG1309	transcriptional regulator
N288_RS18425	COG1956	GAF domain-containing protein
N288_RS18435	COG0626	cystathionine gamma-synthase activity
N288_RS18440	COG2203	Gaf domain
N288_RS18440	COG2199	diguanylate cyclase activity
N288_RS18450	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N288_RS18465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N288_RS18470	COG0454	-acetyltransferase
N288_RS18475	COG0517	IMP dehydrogenase activity
N288_RS18480	COG0123	including yeast histone deacetylase and acetoin utilization protein
N288_RS18505	COG1605	Chorismate mutase
N288_RS18505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N288_RS18515	COG3118	belongs to the thioredoxin family
N288_RS18520	COG4980	gas vesicle protein
N288_RS18525	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N288_RS18530	COG2309	aminopeptidase activity
N288_RS18535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N288_RS18555	COG4848	Belongs to the UPF0354 family
N288_RS18560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS18580	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
N288_RS18585	COG1363	Peptidase, m42
N288_RS18590	COG5584	Small secreted protein
N288_RS18595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N288_RS18600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N288_RS18615	COG0510	thiamine kinase activity
N288_RS18620	COG1523	belongs to the glycosyl hydrolase 13 family
N288_RS18635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N288_RS18645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N288_RS18650	COG4473	ABC transporter
N288_RS18655	COG1131	(ABC) transporter
N288_RS18670	COG1187	pseudouridine synthase activity
N288_RS18680	COG2244	polysaccharide biosynthetic process
N288_RS18685	COG2081	HI0933 family
N288_RS18695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N288_RS18700	COG0495	leucyl-tRNA aminoacylation
N288_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS18710	COG2610	gluconate transmembrane transporter activity
N288_RS18715	COG3829	transcription factor binding
N288_RS18715	COG3290	protein histidine kinase activity
N288_RS18725	COG2814	Major facilitator Superfamily
N288_RS18730	COG2267	carboxylic ester hydrolase activity
N288_RS18745	COG1242	4 iron, 4 sulfur cluster binding
N288_RS18750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N288_RS18760	COG2267	carboxylic ester hydrolase activity
N288_RS18765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N288_RS18770	COG4990	cell redox homeostasis
N288_RS18775	COG0367	asparagine synthase
N288_RS18780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N288_RS18795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N288_RS18800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N288_RS18835	COG0583	DNA-binding transcription factor activity
N288_RS18840	COG0372	Belongs to the citrate synthase family
N288_RS18850	COG1506	peptidase
N288_RS18855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N288_RS18860	COG1116	anion transmembrane transporter activity
N288_RS18865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N288_RS18870	COG0494	nUDIX hydrolase
N288_RS18890	COG0783	Belongs to the Dps family
N288_RS18900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N288_RS18905	COG1854	S-ribosylhomocysteine lyase activity
N288_RS18910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N288_RS18915	COG0288	reversible hydration of carbon dioxide
N288_RS18925	COG1271	oxidase subunit
N288_RS18930	COG1294	oxidase, subunit
N288_RS18940	COG4948	Mandelate Racemase Muconate Lactonizing
N288_RS18945	COG0318	PFAM AMP-dependent synthetase and ligase
N288_RS18950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N288_RS18955	COG0596	Alpha beta hydrolase
N288_RS18960	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N288_RS18965	COG1169	isochorismate synthase
N288_RS18970	COG1575	Belongs to the MenA family. Type 1 subfamily
N288_RS18975	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N288_RS18980	COG0058	SHG alpha-glucan phosphorylase activity
N288_RS18985	COG0297	glycogen (starch) synthase activity
N288_RS18990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N288_RS18995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
N288_RS19130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS19140	COG1285	pathogenesis
N288_RS19150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS19155	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N288_RS19160	COG0673	inositol 2-dehydrogenase activity
N288_RS19165	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS19170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N288_RS19185	COG1979	alcohol dehydrogenase
N288_RS19190	COG2155	Conserved Protein
N288_RS19195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N288_RS19200	COG3829	transcription factor binding
N288_RS19205	COG1098	S1 RNA binding domain
N288_RS19215	COG0436	Aminotransferase
N288_RS19220	COG1522	sequence-specific DNA binding
N288_RS19230	COG2267	carboxylic ester hydrolase activity
N288_RS19240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N288_RS19250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N288_RS19260	COG5018	Exonuclease
N288_RS19265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N288_RS19285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N288_RS19285	COG2111	Na H antiporter
N288_RS19290	COG2111	Na H antiporter
N288_RS19295	COG1006	Multisubunit Na H antiporter MnhC subunit
N288_RS19300	COG0651	ATP synthesis coupled electron transport
N288_RS19305	COG1863	multisubunit Na H antiporter MnhE subunit
N288_RS19310	COG2212	antiporter activity
N288_RS19315	COG1320	monovalent cation:proton antiporter activity
N288_RS19320	COG2050	protein possibly involved in aromatic compounds catabolism
N288_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS19370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N288_RS19375	COG2056	Na+-H+ antiporter family
N288_RS19380	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N288_RS19390	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N288_RS19400	COG3584	3D domain protein
N288_RS19410	COG0494	nUDIX hydrolase
N288_RS19415	COG1252	NADH dehydrogenase
N288_RS19420	COG0492	ferredoxin-NADP+ reductase activity
N288_RS19435	COG0316	Belongs to the HesB IscA family
N288_RS19445	COG4844	belongs to the
N288_RS19450	COG1252	NADH dehydrogenase
N288_RS19460	COG4837	Protein of unknown function (DUF1462)
N288_RS19465	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
N288_RS19475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N288_RS19480	COG0460	homoserine dehydrogenase
N288_RS19490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N288_RS19495	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N288_RS19500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N288_RS19510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N288_RS19515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N288_RS19520	COG0647	UMP catabolic process
N288_RS19525	COG2445	Protein of unknown function DUF86
N288_RS19530	COG3300	MHYT domain
N288_RS19530	COG5001	Diguanylate cyclase
N288_RS19545	COG4470	Protein conserved in bacteria
N288_RS19555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N288_RS19560	COG0739	heme binding
N288_RS19565	COG0733	neurotransmitter:sodium symporter activity
N288_RS19570	COG1757	Na H antiporter
N288_RS19585	COG3377	Domain of unknown function (DUF1805)
N288_RS19590	COG0737	Belongs to the 5'-nucleotidase family
N288_RS19595	COG1801	Protein of unknown function DUF72
N288_RS19600	COG0719	Fe-S assembly protein
N288_RS19605	COG0822	iron-sulfur transferase activity
N288_RS19610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N288_RS19615	COG0719	Fe-S assembly protein
N288_RS19620	COG0396	ATPase activity
N288_RS19625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N288_RS19630	COG1464	Belongs to the NlpA lipoprotein family
N288_RS19635	COG2011	ABC-type metal ion transport system permease component
N288_RS19640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N288_RS19650	COG2873	o-acetylhomoserine
N288_RS19660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS19665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N288_RS19680	COG0509	glycine decarboxylation via glycine cleavage system
N288_RS19685	COG1393	Belongs to the ArsC family
N288_RS19690	COG1960	acyl-CoA dehydrogenase activity
N288_RS19695	COG0183	Belongs to the thiolase family
N288_RS19700	COG1024	Enoyl-CoA hydratase
N288_RS19700	COG1250	3-hydroxyacyl-CoA dehydrogenase
N288_RS19710	COG0506	proline dehydrogenase activity
N288_RS19725	COG1120	ATPase activity
N288_RS19730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N288_RS19735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N288_RS19740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N288_RS19760	COG0772	Belongs to the SEDS family
N288_RS19820	COG0004	ammonium transporteR
N288_RS19825	COG2427	Protein of unknown function (DUF1641)
N288_RS19830	COG3383	formate dehydrogenase (NAD+) activity
N288_RS19845	COG4990	cell redox homeostasis
N288_RS19850	COG1733	regulation of RNA biosynthetic process
N288_RS19855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N288_RS19860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N288_RS19865	COG0300	oxidoreductase activity
N288_RS19875	COG0730	response to heat
N288_RS19880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N288_RS19880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N288_RS19885	COG0425	Belongs to the sulfur carrier protein TusA family
N288_RS19885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N288_RS19890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N288_RS19895	COG2210	Belongs to the sulfur carrier protein TusA family
N288_RS19900	COG0425	Belongs to the sulfur carrier protein TusA family
N288_RS19905	COG1937	Protein conserved in bacteria
N288_RS19925	COG4152	abc transporter atp-binding protein
N288_RS19930	COG1121	(ABC) transporter
N288_RS19945	COG0840	transmembrane signaling receptor activity
N288_RS19950	COG2409	Drug exporters of the RND superfamily
N288_RS19950	COG1033	growth of symbiont in host cell
N288_RS19955	COG1846	Transcriptional regulator
N288_RS19965	COG0517	IMP dehydrogenase activity
N288_RS19965	COG1125	glycine betaine transport
N288_RS19970	COG3706	GGDEF domain
N288_RS19975	COG1174	glycine betaine transport
N288_RS19980	COG0517	IMP dehydrogenase activity
N288_RS19980	COG1125	glycine betaine transport
N288_RS19985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS19990	COG0655	NAD(P)H dehydrogenase (quinone) activity
N288_RS20005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N288_RS20010	COG0557	exoribonuclease II activity
N288_RS20015	COG1647	Serine aminopeptidase, S33
N288_RS20020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N288_RS20035	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N288_RS20050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N288_RS20065	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N288_RS20080	COG0740	serine-type endopeptidase activity
N288_RS20085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS20090	COG1481	regulation of sporulation
N288_RS20095	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N288_RS20100	COG1660	Displays ATPase and GTPase activities
N288_RS20105	COG1051	belongs to the nudix hydrolase family
N288_RS20110	COG0492	ferredoxin-NADP+ reductase activity
N288_RS20115	COG0457	Tetratricopeptide repeat
N288_RS20120	COG0140	phosphoribosyl-ATP diphosphatase activity
N288_RS20120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N288_RS20125	COG0107	imidazoleglycerol-phosphate synthase activity
N288_RS20130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N288_RS20135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N288_RS20140	COG0131	Imidazoleglycerol-phosphate dehydratase
N288_RS20145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N288_RS20150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N288_RS20155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N288_RS20160	COG0110	maltose O-acetyltransferase activity
N288_RS20170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N288_RS20180	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N288_RS20185	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N288_RS20190	COG0363	glucosamine-6-phosphate deaminase activity
N288_RS20195	COG2188	Transcriptional regulator
N288_RS20205	COG1950	PFAM Membrane protein of
N288_RS20210	COG3595	metallopeptidase activity
N288_RS20225	COG2755	lipolytic protein G-D-S-L family
N288_RS20230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N288_RS20235	COG0556	nucleotide-excision repair
N288_RS20240	COG4897	Protein conserved in bacteria
N288_RS20250	COG1473	amidohydrolase
N288_RS20255	COG1464	Belongs to the NlpA lipoprotein family
N288_RS20260	COG2011	ABC-type metal ion transport system permease component
N288_RS20265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N288_RS20270	COG4191	Histidine kinase
N288_RS20275	COG0840	transmembrane signaling receptor activity
N288_RS20280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N288_RS20295	COG0673	inositol 2-dehydrogenase activity
N288_RS20300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N288_RS20305	COG0793	Belongs to the peptidase S41A family
N288_RS20305	COG3409	Peptidoglycan-binding domain 1 protein
N288_RS20310	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS20315	COG0791	NLP P60 protein
N288_RS20315	COG3883	PFAM NLP P60 protein
N288_RS20320	COG2177	Part of the ABC transporter FtsEX involved in
N288_RS20325	COG2884	Cell division ATP-binding protein ftsE
N288_RS20335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS20350	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
N288_RS20355	COG0653	protein targeting
N288_RS20380	COG1744	ABC transporter substrate-binding protein PnrA-like
N288_RS20385	COG0840	transmembrane signaling receptor activity
N288_RS20390	COG2059	Chromate
N288_RS20395	COG2059	Chromate
N288_RS20400	COG4326	sporulation control protein
N288_RS20420	COG1516	flagellar protein fliS
N288_RS20425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N288_RS20425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N288_RS20430	COG1334	flagellar protein FlaG
N288_RS20445	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N288_RS20450	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N288_RS20460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N288_RS20465	COG1256	bacterial-type flagellum assembly
N288_RS20465	COG4786	Flagellar basal body rod
N288_RS20485	COG1040	competence protein
N288_RS20490	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N288_RS20500	COG1227	inorganic diphosphatase activity
N288_RS20505	COG1307	EDD domain protein, DegV family
N288_RS20515	COG2197	response regulator
N288_RS20520	COG4585	Histidine kinase
N288_RS20525	COG1739	Uncharacterized protein family UPF0029
N288_RS20530	COG1316	TRANSCRIPTIONal
N288_RS20550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N288_RS20555	COG0653	protein targeting
N288_RS20575	COG1696	Membrane protein involved in D-alanine export
N288_RS20595	COG3266	domain, Protein
N288_RS20595	COG2911	Protein conserved in bacteria
N288_RS20595	COG1361	Conserved repeat domain
N288_RS20605	COG1316	TRANSCRIPTIONal
N288_RS20630	COG0584	glycerophosphoryl diester phosphodiesterase
N288_RS20635	COG0584	glycerophosphoryl diester phosphodiesterase
N288_RS20645	COG3876	Protein conserved in bacteria
N288_RS20650	COG1472	Belongs to the glycosyl hydrolase 3 family
N288_RS20665	COG3853	Toxic anion resistance protein (TelA)
N288_RS20670	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N288_RS20680	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N288_RS20690	COG2267	carboxylic ester hydrolase activity
N288_RS20695	COG0840	transmembrane signaling receptor activity
N288_RS20695	COG3290	protein histidine kinase activity
N288_RS20715	COG3583	domain protein
N288_RS20715	COG3584	3D domain protein
N288_RS20725	COG1361	Conserved repeat domain
N288_RS20735	COG0366	Alpha amylase catalytic
N288_RS20740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N288_RS20745	COG0366	Alpha amylase catalytic
N288_RS20765	COG1609	Transcriptional regulator
N288_RS20780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N288_RS20785	COG1473	amidohydrolase
N288_RS20790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
N288_RS20810	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS20815	COG1312	Catalyzes the dehydration of D-mannonate
N288_RS20820	COG0800	Aldolase
N288_RS20825	COG1063	alcohol dehydrogenase
N288_RS20830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
N288_RS20840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N288_RS20845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N288_RS20860	COG1609	Transcriptional regulator
N288_RS20865	COG0726	polysaccharide deacetylase
N288_RS20870	COG1215	transferase activity, transferring glycosyl groups
N288_RS20880	COG0366	Alpha amylase catalytic
N288_RS20900	COG5632	N-Acetylmuramoyl-L-alanine amidase
N288_RS20900	COG3409	Peptidoglycan-binding domain 1 protein
N288_RS20900	COG1388	LysM domain
N288_RS20915	COG0402	S-adenosylhomocysteine deaminase activity
N288_RS20920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N288_RS20925	COG1914	H( )-stimulated, divalent metal cation uptake system
N288_RS20935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N288_RS20950	COG1653	transport
N288_RS20955	COG0395	ABC-type sugar transport system, permease component
N288_RS20960	COG4209	transmembrane transport
N288_RS20965	COG5578	integral membrane protein
N288_RS20975	COG2188	Transcriptional regulator
N288_RS20990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N288_RS21005	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N288_RS21025	COG1361	Conserved repeat domain
N288_RS21035	COG2188	Transcriptional regulator
N288_RS21040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N288_RS21045	COG2222	sugar isomerase
N288_RS21050	COG0531	amino acid
N288_RS21055	COG1082	Xylose isomerase domain protein TIM barrel
N288_RS21070	COG0277	FAD linked oxidase domain protein
N288_RS21085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N288_RS21100	COG3732	PTS system glucitol sorbitol-specific
N288_RS21115	COG3711	transcriptional antiterminator
N288_RS21115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS21130	COG1940	carbohydrate kinase activity
N288_RS21135	COG2188	Transcriptional regulator
N288_RS21140	COG2723	6-phospho-beta-galactosidase activity
N288_RS21145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS21145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N288_RS21145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N288_RS21150	COG3711	transcriptional antiterminator
N288_RS21150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N288_RS21155	COG1482	cell wall glycoprotein biosynthetic process
N288_RS21170	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS21175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N288_RS21200	COG2723	6-phospho-beta-galactosidase activity
N288_RS21205	COG2207	Transcriptional regulator
N288_RS21205	COG4753	response regulator
N288_RS21205	COG2207	Transcriptional regulator
N288_RS21205	COG4753	response regulator
N288_RS21210	COG2972	Histidine kinase
N288_RS21220	COG1175	transmembrane transport
N288_RS21240	COG4821	SIS domain
N288_RS21245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N288_RS21250	COG0363	glucosamine-6-phosphate deaminase activity
N288_RS21290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N288_RS21305	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
N288_RS21310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N288_RS21315	COG1609	Transcriptional regulator
N288_RS21320	COG0395	ABC-type sugar transport system, permease component
N288_RS21325	COG1175	transmembrane transport
N288_RS21330	COG1653	transport
N288_RS21335	COG0698	ribose 5-phosphate isomerase
N288_RS21350	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
N288_RS21360	COG3458	cephalosporin-C deacetylase activity
N288_RS21370	COG0383	alpha-mannosidase activity
N288_RS21380	COG0395	ABC-type sugar transport system, permease component
N288_RS21390	COG1653	transport
N288_RS21410	COG0395	ABC-type sugar transport system, permease component
N288_RS21415	COG1175	transmembrane transport
N288_RS21425	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N288_RS21435	COG4753	response regulator
N288_RS21435	COG2207	Transcriptional regulator
N288_RS21440	COG2972	Histidine kinase
N288_RS21445	COG5578	integral membrane protein
N288_RS21450	COG2304	oxidoreductase activity
N288_RS21540	COG2814	Major facilitator Superfamily
N288_RS21555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N288_RS21570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N288_RS21590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N288_RS21600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N288_RS21610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N288_RS21615	COG0673	inositol 2-dehydrogenase activity
N288_RS21640	COG0438	transferase activity, transferring glycosyl groups
N288_RS21650	COG0438	transferase activity, transferring glycosyl groups
N288_RS21650	COG0297	glycogen (starch) synthase activity
N288_RS21655	COG0438	transferase activity, transferring glycosyl groups
N288_RS21660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N288_RS21665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N288_RS21670	COG1086	Polysaccharide biosynthesis protein
N288_RS21675	COG4464	protein tyrosine phosphatase activity
N288_RS21680	COG0489	protein tyrosine kinase activity
N288_RS21685	COG3944	biosynthesis protein
N288_RS21695	COG2356	endonuclease I
N288_RS21700	COG0737	Belongs to the 5'-nucleotidase family
N288_RS21735	COG0438	transferase activity, transferring glycosyl groups
N288_RS21740	COG0728	peptidoglycan biosynthetic process
N288_RS21750	COG1595	DNA-templated transcription, initiation
N288_RS21770	COG4193	domain, Protein
N288_RS21770	COG5263	repeat protein
N288_RS21775	COG0791	NLP P60 protein
N288_RS21775	COG1388	LysM domain
N288_RS21780	COG1404	Belongs to the peptidase S8 family
N288_RS21800	COG0737	Belongs to the 5'-nucleotidase family
N288_RS21820	COG4715	Zinc finger, swim domain protein
N288_RS21825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N288_RS21850	COG0629	single-stranded DNA binding
N288_RS21880	COG4786	Flagellar basal body rod
N288_RS21885	COG4786	Flagellar basal body rod
N288_RS21890	COG1077	Cell shape determining protein MreB Mrl
N288_RS21895	COG1609	Transcriptional regulator
N288_RS21900	COG0791	NLP P60 protein
N288_RS21900	COG1388	LysM domain
N288_RS21905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N288_RS21920	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
N288_RS21930	COG0739	heme binding
N288_RS21940	COG2385	sporulation resulting in formation of a cellular spore
N288_RS21960	COG1007	ATP synthesis coupled electron transport
N288_RS21965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N288_RS21970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N288_RS21975	COG0713	ATP synthesis coupled electron transport
N288_RS21980	COG0839	Belongs to the complex I subunit 6 family
N288_RS21985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N288_RS21990	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
N288_RS21995	COG0649	NAD binding
N288_RS22000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N288_RS22005	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N288_RS22010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N288_RS22015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N288_RS22020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N288_RS22025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N288_RS22035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N288_RS22040	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N288_RS22045	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N288_RS22050	COG0356	it plays a direct role in the translocation of protons across the membrane
N288_RS22065	COG1404	Belongs to the peptidase S8 family
N288_RS22075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N288_RS22085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N288_RS22095	COG1595	DNA-templated transcription, initiation
N288_RS22105	COG0698	ribose 5-phosphate isomerase
N288_RS22120	COG0840	transmembrane signaling receptor activity
N288_RS22130	COG1971	Probably functions as a manganese efflux pump
N288_RS22135	COG0009	L-threonylcarbamoyladenylate synthase
N288_RS22155	COG2890	protein-(glutamine-N5) methyltransferase activity
N288_RS22160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N288_RS22170	COG1435	thymidine kinase activity
N288_RS22180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N288_RS22185	COG1494	fructose-1,6-bisphosphatase
N288_RS22195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N288_RS22200	COG0191	fructose-bisphosphate aldolase activity
N288_RS22205	COG2204	response regulator
N288_RS22215	COG4821	SIS domain
N288_RS22225	COG3343	RNA polymerase activity
N288_RS22235	COG1703	isobutyryl-CoA mutase activity
N288_RS22235	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N288_RS22235	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
N288_RS22245	COG1960	acyl-CoA dehydrogenase activity
N288_RS22250	COG1960	acyl-CoA dehydrogenase activity
N288_RS22255	COG1250	3-hydroxyacyl-CoA dehydrogenase
N288_RS22260	COG0183	Belongs to the thiolase family
N288_RS22265	COG0247	lactate metabolic process
N288_RS22265	COG2181	nitrate reductase activity
N288_RS22270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N288_RS22275	COG4294	response to UV
N288_RS22290	COG0018	arginyl-trna synthetase
N288_RS22295	COG4506	Protein conserved in bacteria
N288_RS22300	COG0010	Belongs to the arginase family
N288_RS22305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N288_RS22310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N288_RS22320	COG1994	Peptidase M50
N288_RS22330	COG3465	dGTPase activity
N288_RS22335	COG1078	dGTPase activity
N288_RS22340	COG4844	belongs to the
N288_RS22355	COG0280	phosphate acetyltransferase
N288_RS22360	COG3253	May function as heme-dependent peroxidase
N288_RS22370	COG3773	Cell wall hydrolase
N288_RS22380	COG2363	Small membrane protein
N288_RS22395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N288_RS22410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N288_RS22415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N288_RS22420	COG0314	molybdopterin synthase activity
N288_RS22425	COG0746	molybdenum cofactor guanylyltransferase activity
N288_RS22445	COG0642	Histidine kinase
N288_RS22450	COG0745	RESPONSE REGULATOR receiver
N288_RS22455	COG0351	phosphomethylpyrimidine kinase
N288_RS22460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N288_RS22475	COG1131	(ABC) transporter
N288_RS22490	COG2133	pyrroloquinoline quinone binding
N288_RS22495	COG0561	phosphatase activity
N288_RS22525	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS22530	COG2031	fatty acid transporter
N288_RS22535	COG0789	Transcriptional regulator
N288_RS22540	COG1132	(ABC) transporter
N288_RS22545	COG3314	Sporulation integral membrane protein YlbJ
N288_RS22560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N288_RS22565	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N288_RS22570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N288_RS22575	COG0366	Alpha amylase catalytic
N288_RS22585	COG2226	methyltransferase
N288_RS22590	COG0492	ferredoxin-NADP+ reductase activity
N288_RS22595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N288_RS22610	COG4187	Peptidase family M20/M25/M40
N288_RS22615	COG0346	lactoylglutathione lyase activity
N288_RS22625	COG2195	Cleaves the N-terminal amino acid of tripeptides
N288_RS22660	COG4211	Belongs to the binding-protein-dependent transport system permease family
N288_RS22665	COG1129	ABC transporter
N288_RS22675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N288_RS22675	COG2207	Transcriptional regulator
N288_RS22680	COG3275	phosphorelay sensor kinase activity
N288_RS22690	COG2207	Transcriptional regulator
N288_RS22690	COG4753	response regulator
N288_RS22725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N288_RS22725	COG2190	(PTS) system
N288_RS22725	COG1263	PTS System
N288_RS22735	COG0477	Major facilitator Superfamily
N288_RS22745	COG2080	2 iron, 2 sulfur cluster binding
N288_RS22755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N288_RS22760	COG2068	MobA-Related Protein
N288_RS22765	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
N288_RS22770	COG0745	RESPONSE REGULATOR receiver
N288_RS22775	COG0642	Histidine kinase
N288_RS22780	COG1136	(ABC) transporter
N288_RS22785	COG0577	efflux transmembrane transporter activity
N288_RS22790	COG1279	arginine transmembrane transporter activity
N288_RS22795	COG0450	alkyl hydroperoxide reductase
N288_RS22800	COG3634	alkyl hydroperoxide reductase activity
N288_RS22805	COG2814	Major facilitator Superfamily
N288_RS22810	COG1309	transcriptional regulator
N288_RS22830	COG0300	oxidoreductase activity
N288_RS22835	COG0640	Transcriptional regulator
N288_RS22850	COG2368	4-hydroxyphenylacetate
N288_RS22855	COG3739	integral membrane protein
N288_RS22860	COG3655	Transcriptional regulator
N288_RS22870	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS22880	COG0662	Cupin 2, conserved barrel domain protein
N288_RS22895	COG5577	PFAM Coat F domain
N288_RS22900	COG1063	alcohol dehydrogenase
N288_RS22910	COG5577	PFAM Coat F domain
N288_RS22915	COG0753	catalase activity
N288_RS22945	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
N288_RS22950	COG1683	Conserved Protein
N288_RS22960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N288_RS22975	COG0295	cytidine deaminase activity
N288_RS22985	COG2323	membrane
N288_RS23010	COG2188	Transcriptional regulator
N288_RS23015	COG1263	PTS System
N288_RS23015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N288_RS23020	COG1388	LysM domain
N288_RS23025	COG5002	protein histidine kinase activity
N288_RS23030	COG0745	RESPONSE REGULATOR receiver
N288_RS23060	COG3386	PFAM SMP-30 Gluconolaconase
N288_RS23085	COG1846	Transcriptional regulator
N288_RS23090	COG1380	Effector of murein hydrolase LrgA
N288_RS23095	COG1346	cytolysis
N288_RS23110	COG1131	(ABC) transporter
N288_RS23120	COG2816	NAD+ diphosphatase activity
N288_RS23125	COG1266	CAAX protease self-immunity
N288_RS23130	COG4978	Transcriptional regulator
N288_RS23130	COG0789	Transcriptional regulator
N288_RS23155	COG1263	PTS System
N288_RS23155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N288_RS23155	COG2190	(PTS) system
N288_RS23160	COG4948	Mandelate Racemase Muconate Lactonizing
N288_RS23165	COG2188	Transcriptional regulator
N288_RS23200	COG1720	tRNA m6t6A37 methyltransferase activity
N288_RS23220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N288_RS23270	COG3708	Transcriptional regulator
N288_RS23270	COG2207	Transcriptional regulator
N288_RS23285	COG0596	Alpha beta hydrolase
N288_RS23290	COG2808	Putative FMN-binding domain
N288_RS23295	COG0456	acetyltransferase
N288_RS23300	COG1846	Transcriptional regulator
N288_RS23330	COG1027	Aspartate ammonia-lyase
N288_RS23340	COG2807	transmembrane transport
N288_RS23350	COG1028	Short-chain dehydrogenase reductase Sdr
N288_RS23435	COG1329	Transcriptional regulator
N288_RS23440	COG0456	acetyltransferase
N288_RS23470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N288_RS23495	COG3290	protein histidine kinase activity
N288_RS23495	COG0840	transmembrane signaling receptor activity
N288_RS23505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N288_RS23510	COG0346	lactoylglutathione lyase activity
N288_RS23515	COG0431	NADPH-dependent FMN reductase
N288_RS23520	COG1846	Transcriptional regulator
N288_RS23545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N288_RS23550	COG1131	(ABC) transporter
N288_RS23565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N288_RS23580	COG5002	protein histidine kinase activity
N288_RS23580	COG3850	Histidine kinase
N288_RS23585	COG0745	RESPONSE REGULATOR receiver
N288_RS23605	COG2205	protein histidine kinase activity
N288_RS23615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N288_RS23660	COG2304	oxidoreductase activity
N288_RS23695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N288_RS23700	COG2814	Major facilitator Superfamily
N288_RS23710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N288_RS23740	COG3142	Participates in the control of copper homeostasis
N288_RS23750	COG1113	amino acid transport
N288_RS23755	COG1785	Belongs to the alkaline phosphatase family
N288_RS23765	COG2318	DinB family
N288_RS23775	COG0577	efflux transmembrane transporter activity
N288_RS23780	COG1136	(ABC) transporter
N288_RS23795	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS23800	COG0697	spore germination
N288_RS23815	COG1126	abc transporter atp-binding protein
N288_RS23820	COG0765	amino acid transport
N288_RS23840	COG2113	Glycine betaine
N288_RS23845	COG4176	ABC-type proline glycine betaine transport system permease component
N288_RS23850	COG0517	IMP dehydrogenase activity
N288_RS23850	COG4175	Glycine betaine
N288_RS23855	COG1510	regulation of RNA biosynthetic process
N288_RS23865	COG3420	alginic acid biosynthetic process
N288_RS23875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N288_RS23880	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N288_RS23885	COG1120	ATPase activity
N288_RS23890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N288_RS23895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N288_RS23905	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N288_RS23920	COG5609	conserved protein (DUF2294)
N288_RS23925	COG2427	Protein of unknown function (DUF1641)
N288_RS23930	COG3383	formate dehydrogenase (NAD+) activity
N288_RS23935	COG2116	formate transmembrane transporter activity
N288_RS23960	COG2223	nitrite transmembrane transporter activity
N288_RS23965	COG3279	Response regulator of the LytR AlgR family
N288_RS23970	COG3275	phosphorelay sensor kinase activity
N288_RS23975	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N288_RS23980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N288_RS23985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N288_RS23990	COG4853	Protein conserved in bacteria
N288_RS23995	COG4863	YycH protein
N288_RS24000	COG5002	protein histidine kinase activity
N288_RS24005	COG0745	RESPONSE REGULATOR receiver
N288_RS24010	COG0741	lytic transglycosylase activity
N288_RS24010	COG1196	nuclear chromosome segregation
N288_RS24010	COG0739	heme binding
N288_RS24035	COG1136	(ABC) transporter
N288_RS24035	COG0577	efflux transmembrane transporter activity
N288_RS24040	COG1136	(ABC) transporter
N288_RS24045	COG3850	Histidine kinase
N288_RS24045	COG5002	protein histidine kinase activity
N288_RS24050	COG0745	RESPONSE REGULATOR receiver
N288_RS24065	COG0305	Participates in initiation and elongation during chromosome replication
N288_RS24070	COG0359	binds to the 23S rRNA
N288_RS24075	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N288_RS24085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N288_RS24090	COG0629	single-stranded DNA binding
N288_RS24095	COG0360	Binds together with S18 to 16S ribosomal RNA
N288_RS24100	COG0438	transferase activity, transferring glycosyl groups
N288_RS24105	COG0671	phosphoesterase, PA-phosphatase related
N288_RS24110	COG0012	GTP binding
N288_RS24115	COG4481	Protein conserved in bacteria
N288_RS24120	COG0668	transmembrane transport
N288_RS24135	COG1475	DNA binding
N288_RS24140	COG1192	Involved in chromosome partitioning
N288_RS24150	COG1475	DNA binding
N288_RS24155	COG0357	Ribosomal RNA small subunit methyltransferase G
N288_RS24165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N288_RS24170	COG1847	R3H domain protein
N288_RS24260	COG1309	transcriptional regulator
N288_RS24290	COG2340	Cysteine-rich secretory protein family
N288_RS24310	COG1366	Belongs to the anti-sigma-factor antagonist family
N288_RS24345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N288_RS24365	COG1596	polysaccharide export
N288_RS24365	COG1555	photosystem II stabilization
N288_RS24370	COG1674	ftsk spoiiie
N288_RS24385	COG1405	negative regulation of cell septum assembly
N288_RS24385	COG3012	SEC-C Motif Domain Protein
N288_RS24390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N288_RS24390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N288_RS24395	COG1361	Conserved repeat domain
N288_RS24400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N288_RS24415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N288_RS24440	COG0791	NLP P60 protein