locus-tag	class	description
CKF48_RS00005	COG1368	sulfuric ester hydrolase activity
CKF48_RS00015	COG2814	Major facilitator Superfamily
CKF48_RS00020	COG1309	transcriptional regulator
CKF48_RS00025	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CKF48_RS00040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CKF48_RS00045	COG3162	membrane
CKF48_RS00060	COG4846	Membrane protein involved in cytochrome C biogenesis
CKF48_RS00065	COG2201	protein-glutamate methylesterase activity
CKF48_RS00070	COG0785	Cytochrome C biogenesis protein
CKF48_RS00080	COG3763	UPF0154 protein
CKF48_RS00100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CKF48_RS00105	COG1388	LysM domain
CKF48_RS00110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CKF48_RS00140	COG0174	glutamine synthetase
CKF48_RS00145	COG0789	Transcriptional regulator
CKF48_RS00150	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CKF48_RS00160	COG2860	membrane
CKF48_RS00165	COG0464	growth
CKF48_RS00170	COG1923	regulation of RNA biosynthetic process
CKF48_RS00175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CKF48_RS00180	COG1077	Cell shape determining protein MreB Mrl
CKF48_RS00185	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CKF48_RS00190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CKF48_RS00200	COG4550	Control of competence regulator ComK, YlbF/YmcA
CKF48_RS00205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKF48_RS00210	COG1013	pyruvate-flavodoxin oxidoreductase activity
CKF48_RS00215	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CKF48_RS00215	COG0674	pyruvate-flavodoxin oxidoreductase activity
CKF48_RS00225	COG2359	stage V sporulation protein S
CKF48_RS00230	COG1692	metallophosphoesterase
CKF48_RS00235	COG1418	mRNA catabolic process
CKF48_RS00240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CKF48_RS00245	COG1058	Belongs to the CinA family
CKF48_RS00245	COG1546	Belongs to the CinA family
CKF48_RS00250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CKF48_RS00255	COG1426	Protein conserved in bacteria
CKF48_RS00270	COG0300	oxidoreductase activity
CKF48_RS00275	COG0612	Peptidase, M16
CKF48_RS00280	COG0612	Peptidase, M16
CKF48_RS00285	COG1079	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS00290	COG4603	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS00295	COG3845	ABC transporter
CKF48_RS00300	COG1744	ABC transporter substrate-binding protein PnrA-like
CKF48_RS00305	COG2188	Transcriptional regulator
CKF48_RS00310	COG4980	gas vesicle protein
CKF48_RS00310	COG1674	ftsk spoiiie
CKF48_RS00320	COG0740	serine-type endopeptidase activity
CKF48_RS00325	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CKF48_RS00335	COG0527	aspartate kinase activity
CKF48_RS00340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKF48_RS00345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKF48_RS00350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_RS00360	COG0612	Peptidase, M16
CKF48_RS00365	COG0726	polysaccharide deacetylase
CKF48_RS00370	COG1185	polyribonucleotide nucleotidyltransferase activity
CKF48_RS00380	COG0196	riboflavin kinase activity
CKF48_RS00385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CKF48_RS00395	COG1550	Protein conserved in bacteria
CKF48_RS00405	COG1358	cellular component organization or biogenesis
CKF48_RS00410	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CKF48_RS00420	COG0779	Required for maturation of 30S ribosomal subunits
CKF48_RS00425	COG2176	DNA-directed DNA polymerase activity
CKF48_RS00430	COG0442	prolyl-tRNA aminoacylation
CKF48_RS00435	COG0750	zinc metalloprotease
CKF48_RS00440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CKF48_RS00445	COG4589	Belongs to the CDS family
CKF48_RS00450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CKF48_RS00455	COG0233	cytoplasmic translational termination
CKF48_RS00465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CKF48_RS00485	COG1191	sigma factor activity
CKF48_RS00490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CKF48_RS00495	COG1776	CheC inhibitor of MCP methylation
CKF48_RS00500	COG0835	chemotaxis
CKF48_RS00505	COG0643	Histidine kinase
CKF48_RS00505	COG2198	Histidine kinase
CKF48_RS00510	COG2201	protein-glutamate methylesterase activity
CKF48_RS00515	COG0455	bacterial-type flagellum organization
CKF48_RS00520	COG1419	protein localization to endoplasmic reticulum
CKF48_RS00525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKF48_RS00530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CKF48_RS00535	COG1684	flagellar biosynthetic protein fliR
CKF48_RS00540	COG1987	bacterial-type flagellum assembly
CKF48_RS00545	COG1338	Plays a role in the flagellum-specific transport system
CKF48_RS00550	COG3190	flagellar
CKF48_RS00555	COG2201	protein-glutamate methylesterase activity
CKF48_RS00560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKF48_RS00560	COG1776	CheC inhibitor of MCP methylation
CKF48_RS00565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKF48_RS00570	COG1580	Controls the rotational direction of flagella during chemotaxis
CKF48_RS00575	COG1582	Flagellar protein (FlbD)
CKF48_RS00585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CKF48_RS00600	COG2882	bacterial-type flagellum organization
CKF48_RS00605	COG1157	protein secretion by the type III secretion system
CKF48_RS00615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CKF48_RS00620	COG1766	The M ring may be actively involved in energy transduction
CKF48_RS00625	COG1677	Flagellar hook-basal body complex protein FliE
CKF48_RS00630	COG1558	bacterial-type flagellum-dependent cell motility
CKF48_RS00635	COG1815	bacterial-type flagellum-dependent cell motility
CKF48_RS00645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CKF48_RS00650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CKF48_RS00655	COG4974	Belongs to the 'phage' integrase family
CKF48_RS00660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CKF48_RS00670	COG0758	DNA mediated transformation
CKF48_RS00675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CKF48_RS00680	COG0045	succinate-CoA ligase (ADP-forming) activity
CKF48_RS00695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CKF48_RS00710	COG0335	large ribosomal subunit rRNA binding
CKF48_RS00715	COG0336	Belongs to the RNA methyltransferase TrmD family
CKF48_RS00720	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CKF48_RS00730	COG1837	Belongs to the UPF0109 family
CKF48_RS00740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CKF48_RS00745	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CKF48_RS00750	COG0552	protein localization to endoplasmic reticulum
CKF48_RS00755	COG1196	nuclear chromosome segregation
CKF48_RS00760	COG0571	ribonuclease III activity
CKF48_RS00765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKF48_RS00770	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS00775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CKF48_RS00780	COG0416	fatty acid biosynthetic process
CKF48_RS00785	COG1349	DNA-binding transcription factor activity
CKF48_RS00790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CKF48_RS00795	COG1461	Dihydroxyacetone kinase
CKF48_RS00800	COG1302	Protein conserved in bacteria
CKF48_RS00805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CKF48_RS00815	COG1564	THIamine pyrophosphokinase
CKF48_RS00825	COG1162	GTPase activity
CKF48_RS00830	COG2815	serine threonine protein kinase
CKF48_RS00830	COG0515	serine threonine protein kinase
CKF48_RS00835	COG0631	protein serine/threonine phosphatase activity
CKF48_RS00840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CKF48_RS00845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CKF48_RS00845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKF48_RS00850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CKF48_RS00855	COG0242	peptide deformylase activity
CKF48_RS00860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CKF48_RS00865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CKF48_RS00875	COG0194	GDP metabolic process
CKF48_RS00880	COG2052	Domain of unknown function (DUF370)
CKF48_RS00885	COG1561	YicC-like family, N-terminal region
CKF48_RS00910	COG2197	response regulator
CKF48_RS00925	COG0167	dihydroorotate dehydrogenase activity
CKF48_RS00930	COG0543	2 iron, 2 sulfur cluster binding
CKF48_RS00935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKF48_RS00945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CKF48_RS00950	COG0540	Belongs to the ATCase OTCase family
CKF48_RS00965	COG0564	pseudouridine synthase activity
CKF48_RS00970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CKF48_RS00980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CKF48_RS00985	COG3599	regulation of cell shape
CKF48_RS00990	COG2302	S4 RNA-binding domain
CKF48_RS00995	COG0762	integral membrane protein
CKF48_RS01000	COG1799	cell septum assembly
CKF48_RS01005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CKF48_RS01010	COG1496	oxidoreductase activity
CKF48_RS01015	COG1873	PFAM PRC-barrel domain
CKF48_RS01020	COG1191	sigma factor activity
CKF48_RS01025	COG1191	sigma factor activity
CKF48_RS01035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CKF48_RS01040	COG0849	cell division
CKF48_RS01045	COG3856	small basic protein
CKF48_RS01050	COG3879	Bacterial protein of unknown function (DUF881)
CKF48_RS01055	COG3879	Bacterial protein of unknown function (DUF881)
CKF48_RS01060	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CKF48_RS01075	COG0772	Belongs to the SEDS family
CKF48_RS01085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKF48_RS01090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKF48_RS01095	COG0768	penicillin binding
CKF48_RS01100	COG0768	penicillin binding
CKF48_RS01105	COG4839	cell division protein FtsL
CKF48_RS01110	COG0275	rRNA processing
CKF48_RS01115	COG2001	Belongs to the MraZ family
CKF48_RS01120	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CKF48_RS01130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKF48_RS01145	COG0511	ligase activity, forming carbon-carbon bonds
CKF48_RS01150	COG0439	Biotin carboxylase
CKF48_RS01155	COG0454	-acetyltransferase
CKF48_RS01165	COG1024	Enoyl-CoA hydratase
CKF48_RS01170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CKF48_RS01175	COG1399	metal-binding, possibly nucleic acid-binding protein
CKF48_RS01190	COG3480	Lon protease (S16) C-terminal proteolytic domain
CKF48_RS01195	COG1752	Esterase of the alpha-beta hydrolase superfamily
CKF48_RS01200	COG3314	Sporulation integral membrane protein YlbJ
CKF48_RS01205	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CKF48_RS01210	COG0742	ribosomal rna small subunit methyltransferase
CKF48_RS01225	COG4471	UPF0298 protein
CKF48_RS01230	COG3679	Belongs to the UPF0342 family
CKF48_RS01255	COG2340	Cysteine-rich secretory protein family
CKF48_RS01275	COG3336	cytochrome c oxidase
CKF48_RS01300	COG1612	heme a metabolic process
CKF48_RS01305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CKF48_RS01310	COG0772	Belongs to the SEDS family
CKF48_RS01315	COG4838	Belongs to the UPF0358 family
CKF48_RS01320	COG2066	Belongs to the glutaminase family
CKF48_RS01325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CKF48_RS01330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CKF48_RS01340	COG4896	Protein conserved in bacteria
CKF48_RS01360	COG1217	gtp-binding protein TYPA
CKF48_RS01370	COG0483	inositol monophosphate 1-phosphatase activity
CKF48_RS01380	COG4493	Belongs to the UPF0637 family
CKF48_RS01385	COG4476	Belongs to the UPF0223 family
CKF48_RS01390	COG1982	Orn Lys Arg decarboxylase major
CKF48_RS01415	COG0726	polysaccharide deacetylase
CKF48_RS01435	COG0022	dehydrogenase e1 component
CKF48_RS01455	COG0242	peptide deformylase activity
CKF48_RS01460	COG0561	phosphatase activity
CKF48_RS01465	COG5503	Protein of unknown function (DUF1447)
CKF48_RS01470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CKF48_RS01475	COG0569	domain protein
CKF48_RS01480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_RS01485	COG0450	alkyl hydroperoxide reductase
CKF48_RS01490	COG1473	amidohydrolase
CKF48_RS01495	COG2171	N-acyltransferase activity
CKF48_RS01500	COG0583	DNA-binding transcription factor activity
CKF48_RS01505	COG0517	IMP dehydrogenase activity
CKF48_RS01515	COG4703	Protein of unknown function (DUF1797)
CKF48_RS01530	COG2200	EAL domain
CKF48_RS01535	COG1408	metallophosphoesterase
CKF48_RS01550	COG0835	chemotaxis
CKF48_RS01550	COG0784	Response regulator, receiver
CKF48_RS01560	COG0436	Aminotransferase
CKF48_RS01565	COG2084	Dehydrogenase
CKF48_RS01575	COG2391	methyltransferase activity
CKF48_RS01580	COG0425	Belongs to the sulfur carrier protein TusA family
CKF48_RS01590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKF48_RS01600	COG4873	Protein conserved in bacteria
CKF48_RS01615	COG3949	Membrane
CKF48_RS01620	COG0542	response to heat
CKF48_RS01630	COG1846	Transcriptional regulator
CKF48_RS01635	COG3852	Histidine kinase
CKF48_RS01640	COG2223	nitrite transmembrane transporter activity
CKF48_RS01655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKF48_RS01660	COG0640	Transcriptional regulator
CKF48_RS01665	COG5002	protein histidine kinase activity
CKF48_RS01670	COG0840	transmembrane signaling receptor activity
CKF48_RS01675	COG3594	Acyltransferase
CKF48_RS01730	COG1191	sigma factor activity
CKF48_RS01735	COG1757	Na H antiporter
CKF48_RS01740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CKF48_RS01745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKF48_RS01750	COG3773	Cell wall hydrolase
CKF48_RS01755	COG1595	DNA-templated transcription, initiation
CKF48_RS01760	COG1404	Belongs to the peptidase S8 family
CKF48_RS01760	COG4412	M6 family metalloprotease domain protein
CKF48_RS01780	COG1510	regulation of RNA biosynthetic process
CKF48_RS01785	COG0517	IMP dehydrogenase activity
CKF48_RS01785	COG4175	Glycine betaine
CKF48_RS01790	COG4176	ABC-type proline glycine betaine transport system permease component
CKF48_RS01795	COG2113	Glycine betaine
CKF48_RS01800	COG2268	Band 7 protein
CKF48_RS01805	COG1585	Membrane protein implicated in regulation of membrane protease activity
CKF48_RS01815	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_RS01820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKF48_RS01825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CKF48_RS01835	COG1966	Carbon starvation protein
CKF48_RS01845	COG2197	response regulator
CKF48_RS01850	COG4585	Histidine kinase
CKF48_RS01855	COG0842	Transport permease protein
CKF48_RS01860	COG1131	(ABC) transporter
CKF48_RS01875	COG0004	ammonium transporteR
CKF48_RS01895	COG2155	Conserved Protein
CKF48_RS01915	COG2382	esterase
CKF48_RS01925	COG2153	protein acetylation
CKF48_RS01930	COG2323	membrane
CKF48_RS01940	COG0210	DNA helicase
CKF48_RS01960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_RS01995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CKF48_RS02000	COG0475	glutathione-regulated potassium exporter activity
CKF48_RS02000	COG0569	domain protein
CKF48_RS02005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKF48_RS02010	COG0564	pseudouridine synthase activity
CKF48_RS02020	COG2357	RelA SpoT domain protein
CKF48_RS02030	COG4116	CYTH
CKF48_RS02035	COG0739	heme binding
CKF48_RS02035	COG0741	lytic transglycosylase activity
CKF48_RS02035	COG1196	nuclear chromosome segregation
CKF48_RS02040	COG2346	COG2346, Truncated hemoglobins
CKF48_RS02045	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CKF48_RS02050	COG1164	Oligoendopeptidase f
CKF48_RS02060	COG4862	establishment of competence for transformation
CKF48_RS02065	COG1393	Belongs to the ArsC family
CKF48_RS02070	COG0456	acetyltransferase
CKF48_RS02085	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS02090	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS02095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS02100	COG0601	transmembrane transport
CKF48_RS02105	COG4166	transmembrane transport
CKF48_RS02110	COG0180	Tryptophanyl-tRNA synthetase
CKF48_RS02120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS02125	COG0601	transmembrane transport
CKF48_RS02135	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS02140	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS02145	COG5504	Zn-dependent protease
CKF48_RS02150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKF48_RS02155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_RS02170	COG1744	ABC transporter substrate-binding protein PnrA-like
CKF48_RS02180	COG2267	carboxylic ester hydrolase activity
CKF48_RS02200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CKF48_RS02225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CKF48_RS02230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CKF48_RS02235	COG1763	Mo-molybdopterin cofactor biosynthetic process
CKF48_RS02240	COG0303	'Molybdopterin
CKF48_RS02245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CKF48_RS02250	COG2151	metal-sulfur cluster biosynthetic enzyme
CKF48_RS02255	COG1073	alpha beta
CKF48_RS02260	COG0561	phosphatase activity
CKF48_RS02270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_RS02275	COG1307	EDD domain protein, DegV family
CKF48_RS02285	COG2996	Protein conserved in bacteria
CKF48_RS02290	COG1666	GTP binding
CKF48_RS02295	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS02305	COG0367	asparagine synthase
CKF48_RS02315	COG3300	MHYT domain
CKF48_RS02315	COG5001	Diguanylate cyclase
CKF48_RS02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_RS02330	COG2311	Membrane
CKF48_RS02335	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS02375	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CKF48_RS02380	COG0398	Pfam SNARE associated Golgi protein
CKF48_RS02390	COG0823	Involved in the tonB-independent uptake of proteins
CKF48_RS02390	COG1506	peptidase
CKF48_RS02390	COG4946	Tricorn protease homolog
CKF48_RS02400	COG4903	ComK protein
CKF48_RS02410	COG0501	Belongs to the peptidase M48B family
CKF48_RS02420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CKF48_RS02425	COG1396	sequence-specific DNA binding
CKF48_RS02430	COG1846	Transcriptional regulator
CKF48_RS02435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKF48_RS02440	COG2368	4-hydroxyphenylacetate
CKF48_RS02445	COG5553	Cysteine dioxygenase type I
CKF48_RS02450	COG1959	2 iron, 2 sulfur cluster binding
CKF48_RS02455	COG1122	ATPase activity
CKF48_RS02500	COG4509	Sortase family
CKF48_RS02520	COG5386	Cell surface protein
CKF48_RS02530	COG1024	Enoyl-CoA hydratase
CKF48_RS02535	COG2267	carboxylic ester hydrolase activity
CKF48_RS02540	COG0431	NADPH-dependent FMN reductase
CKF48_RS02565	COG1464	Belongs to the NlpA lipoprotein family
CKF48_RS02575	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS02580	COG0095	Lipoate-protein ligase
CKF48_RS02595	COG1309	transcriptional regulator
CKF48_RS02600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CKF48_RS02605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CKF48_RS02610	COG2329	Antibiotic biosynthesis monooxygenase
CKF48_RS02615	COG3069	C4-dicarboxylate transmembrane transporter activity
CKF48_RS02625	COG4473	ABC transporter
CKF48_RS02630	COG1131	(ABC) transporter
CKF48_RS02635	COG0537	adenosine 5'-monophosphoramidase activity
CKF48_RS02640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CKF48_RS02655	COG1846	Transcriptional regulator
CKF48_RS02680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKF48_RS02695	COG4717	serine-type aminopeptidase activity
CKF48_RS02700	COG0420	3'-5' exonuclease activity
CKF48_RS02705	COG2197	response regulator
CKF48_RS02710	COG4585	Histidine kinase
CKF48_RS02725	COG1131	(ABC) transporter
CKF48_RS02730	COG1668	transmembrane transport
CKF48_RS02745	COG1024	Enoyl-CoA hydratase
CKF48_RS02755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKF48_RS02760	COG0561	phosphatase activity
CKF48_RS02770	COG4399	Belongs to the UPF0754 family
CKF48_RS02780	COG0189	ligase activity
CKF48_RS02785	COG0189	ligase activity
CKF48_RS02790	COG0189	ligase activity
CKF48_RS02810	COG1937	Protein conserved in bacteria
CKF48_RS02830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKF48_RS02845	COG1301	dicarboxylic acid transport
CKF48_RS02850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKF48_RS02855	COG1253	flavin adenine dinucleotide binding
CKF48_RS02860	COG3850	Histidine kinase
CKF48_RS02860	COG5002	protein histidine kinase activity
CKF48_RS02865	COG0745	RESPONSE REGULATOR receiver
CKF48_RS02870	COG0640	Transcriptional regulator
CKF48_RS02880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_RS02885	COG2719	SpoVR family
CKF48_RS02900	COG2197	response regulator
CKF48_RS02905	COG4585	Histidine kinase
CKF48_RS02905	COG2203	Gaf domain
CKF48_RS02910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKF48_RS02915	COG3153	acetyltransferase
CKF48_RS02915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKF48_RS02935	COG0564	pseudouridine synthase activity
CKF48_RS02940	COG2261	transglycosylase associated protein
CKF48_RS02945	COG0656	L-ascorbic acid biosynthetic process
CKF48_RS02950	COG3973	AAA domain
CKF48_RS02955	COG1392	Phosphate transport regulator
CKF48_RS02960	COG0306	phosphate transporter
CKF48_RS02965	COG2252	PERMEase
CKF48_RS02970	COG1823	symporter activity
CKF48_RS02975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_RS02980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKF48_RS02985	COG1309	transcriptional regulator
CKF48_RS02995	COG0460	homoserine dehydrogenase
CKF48_RS03000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_RS03010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_RS03015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_RS03040	COG2766	serine protein kinase
CKF48_RS03045	COG0778	Nitroreductase
CKF48_RS03050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CKF48_RS03060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CKF48_RS03065	COG3382	B3 4 domain protein
CKF48_RS03070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS03075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS03080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_RS03085	COG1120	ATPase activity
CKF48_RS03200	COG0735	belongs to the Fur family
CKF48_RS03205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CKF48_RS03215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKF48_RS03220	COG0070	glutamate synthase
CKF48_RS03220	COG0069	glutamate synthase activity
CKF48_RS03220	COG0067	glutamate synthase
CKF48_RS03225	COG4129	membrane
CKF48_RS03230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS03235	COG0601	transmembrane transport
CKF48_RS03240	COG0747	negative chemotaxis
CKF48_RS03245	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS03250	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS03255	COG1132	(ABC) transporter
CKF48_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS03285	COG1988	membrane-bound metal-dependent
CKF48_RS03315	COG1090	epimerase
CKF48_RS03330	COG1132	(ABC) transporter
CKF48_RS03335	COG1132	(ABC) transporter
CKF48_RS03345	COG2076	Multidrug Resistance protein
CKF48_RS03350	COG2076	Multidrug Resistance protein
CKF48_RS03355	COG1309	transcriptional regulator
CKF48_RS03385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CKF48_RS03390	COG2508	Transcriptional regulator
CKF48_RS03395	COG1473	amidohydrolase
CKF48_RS03415	COG1657	PFAM Prenyltransferase squalene oxidase
CKF48_RS03420	COG1473	amidohydrolase
CKF48_RS03435	COG0788	formyltetrahydrofolate deformylase activity
CKF48_RS03460	COG2207	Transcriptional regulator
CKF48_RS03460	COG3708	Transcriptional regulator
CKF48_RS03465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CKF48_RS03470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CKF48_RS03475	COG1136	(ABC) transporter
CKF48_RS03480	COG0577	efflux transmembrane transporter activity
CKF48_RS03510	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CKF48_RS03515	COG3844	kynureninase activity
CKF48_RS03530	COG0385	Bile acid
CKF48_RS03535	COG0277	FAD linked oxidase domain protein
CKF48_RS03540	COG2186	Transcriptional regulator
CKF48_RS03545	COG0386	Belongs to the glutathione peroxidase family
CKF48_RS03550	COG0506	proline dehydrogenase activity
CKF48_RS03555	COG1556	Lactate utilization protein
CKF48_RS03560	COG1139	Iron-sulfur cluster binding protein
CKF48_RS03565	COG0247	lactate metabolic process
CKF48_RS03585	COG0840	transmembrane signaling receptor activity
CKF48_RS03605	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS03620	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS03625	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS03630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKF48_RS03635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CKF48_RS03640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKF48_RS03645	COG5337	Spore coat protein CotH
CKF48_RS03655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKF48_RS03660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CKF48_RS03680	COG0535	radical SAM domain protein
CKF48_RS03690	COG0387	Pfam Sodium calcium exchanger
CKF48_RS03695	COG0477	Major facilitator Superfamily
CKF48_RS03705	COG1295	ribonuclease BN
CKF48_RS03715	COG4840	Belongs to the UPF0435 family
CKF48_RS03720	COG0024	Methionine aminopeptidase
CKF48_RS03725	COG0693	protein deglycase activity
CKF48_RS03740	COG2313	pseudouridylate synthase activity
CKF48_RS03750	COG1360	Flagellar Motor Protein
CKF48_RS03755	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CKF48_RS03775	COG2309	aminopeptidase activity
CKF48_RS03790	COG1970	mechanosensitive ion channel activity
CKF48_RS03795	COG0670	Belongs to the BI1 family
CKF48_RS03810	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CKF48_RS03815	COG0805	protein transport
CKF48_RS03825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKF48_RS03840	COG1607	acyl-coa hydrolase
CKF48_RS03845	COG0598	Magnesium transport protein CorA
CKF48_RS03855	COG1595	DNA-templated transcription, initiation
CKF48_RS03860	COG2244	polysaccharide biosynthetic process
CKF48_RS03865	COG0488	(ABC) transporter
CKF48_RS03870	COG2197	response regulator
CKF48_RS03910	COG0723	plastoquinol--plastocyanin reductase activity
CKF48_RS03910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKF48_RS03915	COG0513	Belongs to the DEAD box helicase family
CKF48_RS03920	COG2814	Major facilitator Superfamily
CKF48_RS03930	COG0604	alcohol dehydrogenase
CKF48_RS03935	COG0024	Methionine aminopeptidase
CKF48_RS03945	COG3275	phosphorelay sensor kinase activity
CKF48_RS03955	COG1966	Carbon starvation protein
CKF48_RS03960	COG2176	DNA-directed DNA polymerase activity
CKF48_RS03980	COG0579	oxidoreductase
CKF48_RS03990	COG0277	FAD linked oxidase domain protein
CKF48_RS03995	COG2186	Transcriptional regulator
CKF48_RS04015	COG1301	dicarboxylic acid transport
CKF48_RS04030	COG4565	transcriptional regulatory protein
CKF48_RS04035	COG3290	protein histidine kinase activity
CKF48_RS04040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKF48_RS04050	COG0427	acetyl-CoA hydrolase
CKF48_RS04055	COG3279	Response regulator of the LytR AlgR family
CKF48_RS04065	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS04070	COG2011	ABC-type metal ion transport system permease component
CKF48_RS04075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_RS04095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKF48_RS04100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKF48_RS04120	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CKF48_RS04125	COG3850	Histidine kinase
CKF48_RS04125	COG5002	protein histidine kinase activity
CKF48_RS04130	COG0745	RESPONSE REGULATOR receiver
CKF48_RS04135	COG0667	Aldo Keto reductase
CKF48_RS04160	COG2002	toxin-antitoxin pair type II binding
CKF48_RS04185	COG2819	hydrolase of the alpha beta superfamily
CKF48_RS04190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS04195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS04205	COG5566	PFAM Mor transcription activator
CKF48_RS04210	COG0217	transcriptional regulatory protein
CKF48_RS04220	COG1846	Transcriptional regulator
CKF48_RS04235	COG0372	Belongs to the citrate synthase family
CKF48_RS04240	COG0583	DNA-binding transcription factor activity
CKF48_RS04245	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS04250	COG0840	transmembrane signaling receptor activity
CKF48_RS04255	COG0017	Asparaginyl-tRNA synthetase
CKF48_RS04270	COG1757	Na H antiporter
CKF48_RS04275	COG1473	amidohydrolase
CKF48_RS04280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKF48_RS04285	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS04290	COG3829	transcription factor binding
CKF48_RS04295	COG1132	(ABC) transporter
CKF48_RS04300	COG1132	(ABC) transporter
CKF48_RS04305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKF48_RS04320	COG5002	protein histidine kinase activity
CKF48_RS04325	COG0745	RESPONSE REGULATOR receiver
CKF48_RS04330	COG1388	LysM domain
CKF48_RS04335	COG0456	acetyltransferase
CKF48_RS04345	COG1595	DNA-templated transcription, initiation
CKF48_RS04355	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CKF48_RS04355	COG2755	lipolytic protein G-D-S-L family
CKF48_RS04375	COG4211	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS04380	COG1129	ABC transporter
CKF48_RS04390	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CKF48_RS04395	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CKF48_RS04400	COG1850	ribulose-bisphosphate carboxylase activity
CKF48_RS04410	COG0235	Class ii aldolase
CKF48_RS04415	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CKF48_RS04425	COG0604	alcohol dehydrogenase
CKF48_RS04460	COG2318	DinB family
CKF48_RS04480	COG3011	Protein conserved in bacteria
CKF48_RS04505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_RS04520	COG0586	Pfam SNARE associated Golgi protein
CKF48_RS04525	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CKF48_RS04530	COG1473	amidohydrolase
CKF48_RS04545	COG2814	Major facilitator Superfamily
CKF48_RS04555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CKF48_RS04570	COG3835	regulator
CKF48_RS04590	COG0529	Catalyzes the synthesis of activated sulfate
CKF48_RS04595	COG2046	Belongs to the sulfate adenylyltransferase family
CKF48_RS04600	COG0583	DNA-binding transcription factor activity
CKF48_RS04605	COG1063	alcohol dehydrogenase
CKF48_RS04610	COG0730	response to heat
CKF48_RS04635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKF48_RS04645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CKF48_RS04645	COG0165	Argininosuccinate lyase
CKF48_RS04670	COG0583	DNA-binding transcription factor activity
CKF48_RS04675	COG4122	O-methyltransferase activity
CKF48_RS04680	COG1072	(Pantothenic acid kinase))
CKF48_RS04690	COG1131	(ABC) transporter
CKF48_RS04705	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CKF48_RS04715	COG1764	response to oxidative stress
CKF48_RS04720	COG0477	Major facilitator Superfamily
CKF48_RS04730	COG0659	secondary active sulfate transmembrane transporter activity
CKF48_RS04745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_RS04750	COG0346	lactoylglutathione lyase activity
CKF48_RS04760	COG1597	lipid kinase activity
CKF48_RS04765	COG1335	isochorismatase
CKF48_RS04770	COG2814	Major facilitator Superfamily
CKF48_RS04775	COG1011	Hydrolase
CKF48_RS04785	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS04790	COG0737	Belongs to the 5'-nucleotidase family
CKF48_RS04795	COG4191	Histidine kinase
CKF48_RS04810	COG0500	methyltransferase
CKF48_RS04815	COG2226	methyltransferase
CKF48_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS04835	COG0109	protoheme IX farnesyltransferase activity
CKF48_RS04860	COG0604	alcohol dehydrogenase
CKF48_RS04860	COG3321	synthase
CKF48_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS04875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CKF48_RS04880	COG2079	MmgE PrpD family protein
CKF48_RS04900	COG2814	Major facilitator Superfamily
CKF48_RS04915	COG1464	Belongs to the NlpA lipoprotein family
CKF48_RS04920	COG0436	Aminotransferase
CKF48_RS04925	COG2202	Pas domain
CKF48_RS04925	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS04945	COG0456	acetyltransferase
CKF48_RS04950	COG1309	transcriptional regulator
CKF48_RS04960	COG0789	Transcriptional regulator
CKF48_RS04965	COG1253	flavin adenine dinucleotide binding
CKF48_RS04975	COG0183	Belongs to the thiolase family
CKF48_RS04985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CKF48_RS04995	COG0596	Alpha beta hydrolase
CKF48_RS05010	COG0454	-acetyltransferase
CKF48_RS05020	COG4708	membrane
CKF48_RS05025	COG0861	Integral membrane protein TerC family
CKF48_RS05030	COG4187	Peptidase family M20/M25/M40
CKF48_RS05035	COG0527	aspartate kinase activity
CKF48_RS05045	COG4086	secreted protein
CKF48_RS05050	COG0739	heme binding
CKF48_RS05090	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_RS05095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS05100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_RS05110	COG2234	aminopeptidase activity
CKF48_RS05115	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS05125	COG0166	Belongs to the GPI family
CKF48_RS05130	COG5002	protein histidine kinase activity
CKF48_RS05135	COG3853	Toxic anion resistance protein (TelA)
CKF48_RS05140	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CKF48_RS05145	COG5002	protein histidine kinase activity
CKF48_RS05150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKF48_RS05155	COG3764	Sortase (surface protein transpeptidase)
CKF48_RS05165	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS05170	COG1301	dicarboxylic acid transport
CKF48_RS05180	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_RS05190	COG0395	ABC-type sugar transport system, permease component
CKF48_RS05200	COG3842	ATPase activity
CKF48_RS05215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CKF48_RS05220	COG1609	Transcriptional regulator
CKF48_RS05235	COG2207	Transcriptional regulator
CKF48_RS05245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_RS05250	COG1116	anion transmembrane transporter activity
CKF48_RS05255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_RS05260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_RS05265	COG0371	Dehydrogenase
CKF48_RS05270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKF48_RS05275	COG0730	response to heat
CKF48_RS05280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_RS05280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS05285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_RS05285	COG0425	Belongs to the sulfur carrier protein TusA family
CKF48_RS05290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_RS05295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_RS05300	COG2210	Belongs to the sulfur carrier protein TusA family
CKF48_RS05305	COG0425	Belongs to the sulfur carrier protein TusA family
CKF48_RS05310	COG1937	Protein conserved in bacteria
CKF48_RS05325	COG2207	Transcriptional regulator
CKF48_RS05325	COG3708	Transcriptional regulator
CKF48_RS05330	COG2818	Glycosylase
CKF48_RS05340	COG4122	O-methyltransferase activity
CKF48_RS05350	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS05380	COG0666	response to abiotic stimulus
CKF48_RS05400	COG1725	Transcriptional regulator
CKF48_RS05410	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_RS05415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CKF48_RS05420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CKF48_RS05425	COG0471	metal ion transport
CKF48_RS05430	COG0586	Pfam SNARE associated Golgi protein
CKF48_RS05435	COG0454	-acetyltransferase
CKF48_RS05450	COG1785	Belongs to the alkaline phosphatase family
CKF48_RS05470	COG1396	sequence-specific DNA binding
CKF48_RS05475	COG0124	histidyl-tRNA synthetase
CKF48_RS05490	COG0494	nUDIX hydrolase
CKF48_RS05510	COG5658	integral membrane protein
CKF48_RS05515	COG0471	metal ion transport
CKF48_RS05525	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_RS05535	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS05550	COG0154	amidase activity
CKF48_RS05560	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS05565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS05570	COG0601	transmembrane transport
CKF48_RS05575	COG0747	negative chemotaxis
CKF48_RS05600	COG2271	Major facilitator Superfamily
CKF48_RS05605	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS05610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKF48_RS05615	COG2186	Transcriptional regulator
CKF48_RS05620	COG2721	sulfolactate sulfo-lyase activity
CKF48_RS05625	COG1064	alcohol dehydrogenase
CKF48_RS05640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CKF48_RS05645	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CKF48_RS05670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CKF48_RS05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_RS05715	COG3181	Tripartite tricarboxylate transporter family receptor
CKF48_RS05720	COG4565	transcriptional regulatory protein
CKF48_RS05725	COG3290	protein histidine kinase activity
CKF48_RS05735	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CKF48_RS05750	COG0583	DNA-binding transcription factor activity
CKF48_RS05755	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_RS05760	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CKF48_RS05765	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CKF48_RS05770	COG2070	2-Nitropropane dioxygenase
CKF48_RS05785	COG1024	Enoyl-CoA hydratase
CKF48_RS05790	COG0183	Belongs to the thiolase family
CKF48_RS05795	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_RS05800	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS05805	COG1024	Enoyl-CoA hydratase
CKF48_RS05835	COG3396	Phenylacetate-CoA oxygenase
CKF48_RS05840	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CKF48_RS05845	COG1141	Ferredoxin
CKF48_RS05855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_RS05860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_RS05865	COG1131	(ABC) transporter
CKF48_RS05875	COG0745	RESPONSE REGULATOR receiver
CKF48_RS05880	COG2205	protein histidine kinase activity
CKF48_RS05885	COG0861	Integral membrane protein TerC family
CKF48_RS05905	COG3173	Aminoglycoside phosphotransferase
CKF48_RS05920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CKF48_RS05980	COG0840	transmembrane signaling receptor activity
CKF48_RS05985	COG1705	Flagellar rod assembly protein muramidase FlgJ
CKF48_RS06035	COG1136	(ABC) transporter
CKF48_RS06050	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS06060	COG0601	transmembrane transport
CKF48_RS06090	COG0454	-acetyltransferase
CKF48_RS06100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKF48_RS06120	COG1476	TRANSCRIPTIONal
CKF48_RS06125	COG3655	Transcriptional regulator
CKF48_RS06140	COG2112	serine threonine protein kinase
CKF48_RS06150	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS06155	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS06160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS06165	COG0601	transmembrane transport
CKF48_RS06205	COG2080	2 iron, 2 sulfur cluster binding
CKF48_RS06210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CKF48_RS06215	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CKF48_RS06220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CKF48_RS06225	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CKF48_RS06230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CKF48_RS06235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKF48_RS06240	COG2508	Transcriptional regulator
CKF48_RS06245	COG2233	PERMEase
CKF48_RS06250	COG3195	allantoin biosynthetic process
CKF48_RS06250	COG3648	Uricase
CKF48_RS06255	COG2072	flavoprotein involved in K transport
CKF48_RS06260	COG2351	hydroxyisourate hydrolase activity
CKF48_RS06285	COG2356	endonuclease I
CKF48_RS06290	COG2814	Major facilitator Superfamily
CKF48_RS06305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_RS06320	COG0405	Gamma-glutamyltransferase
CKF48_RS06325	COG0154	amidase activity
CKF48_RS06340	COG1193	negative regulation of DNA recombination
CKF48_RS06345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKF48_RS06375	COG4807	Protein conserved in bacteria
CKF48_RS06420	COG0450	alkyl hydroperoxide reductase
CKF48_RS06430	COG0640	Transcriptional regulator
CKF48_RS06480	COG0497	DNA recombination
CKF48_RS06495	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CKF48_RS06515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CKF48_RS06525	COG1597	lipid kinase activity
CKF48_RS06555	COG0747	negative chemotaxis
CKF48_RS06560	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_RS06565	COG1953	Uracil, thiamine, allantoin
CKF48_RS06575	COG3279	Response regulator of the LytR AlgR family
CKF48_RS06580	COG2972	Histidine kinase
CKF48_RS06585	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS06590	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS06610	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_RS06615	COG0402	S-adenosylhomocysteine deaminase activity
CKF48_RS06620	COG0772	Belongs to the SEDS family
CKF48_RS06645	COG2226	methyltransferase
CKF48_RS06655	COG1694	Mazg nucleotide pyrophosphohydrolase
CKF48_RS06670	COG0778	Nitroreductase
CKF48_RS06675	COG1733	regulation of RNA biosynthetic process
CKF48_RS06685	COG1522	sequence-specific DNA binding
CKF48_RS06690	COG1335	isochorismatase
CKF48_RS06720	COG1695	Transcriptional regulator
CKF48_RS06735	COG0577	efflux transmembrane transporter activity
CKF48_RS06740	COG1136	(ABC) transporter
CKF48_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CKF48_RS06765	COG0681	Belongs to the peptidase S26 family
CKF48_RS06770	COG3227	Zinc metalloprotease (Elastase)
CKF48_RS06780	COG3973	AAA domain
CKF48_RS06790	COG2211	Major facilitator Superfamily
CKF48_RS06870	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_RS06895	COG1595	DNA-templated transcription, initiation
CKF48_RS06900	COG3773	Cell wall hydrolase
CKF48_RS06905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKF48_RS06930	COG1227	inorganic diphosphatase activity
CKF48_RS06940	COG1063	alcohol dehydrogenase
CKF48_RS06960	COG0583	DNA-binding transcription factor activity
CKF48_RS06975	COG2124	cytochrome p450
CKF48_RS06980	COG1346	cytolysis
CKF48_RS06985	COG1380	Effector of murein hydrolase LrgA
CKF48_RS07035	COG0006	proline dipeptidase activity
CKF48_RS07040	COG1396	sequence-specific DNA binding
CKF48_RS07045	COG3192	ethanolamine utilization protein
CKF48_RS07055	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CKF48_RS07060	COG0154	amidase activity
CKF48_RS07070	COG1215	transferase activity, transferring glycosyl groups
CKF48_RS07085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CKF48_RS07105	COG3620	sequence-specific DNA binding
CKF48_RS07110	COG5506	Protein of unknown function (DUF1694)
CKF48_RS07120	COG2224	Isocitrate lyase
CKF48_RS07125	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS07130	COG2211	Major facilitator Superfamily
CKF48_RS07155	COG2226	methyltransferase
CKF48_RS07170	COG4851	CamS sex pheromone cAM373 precursor
CKF48_RS07175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CKF48_RS07180	COG0210	DNA helicase
CKF48_RS07185	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CKF48_RS07200	COG4496	protein, YerC YecD
CKF48_RS07205	COG1470	cell adhesion involved in biofilm formation
CKF48_RS07220	COG0151	Belongs to the GarS family
CKF48_RS07225	COG0138	bifunctional purine biosynthesis protein purh
CKF48_RS07230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CKF48_RS07240	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CKF48_RS07255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CKF48_RS07260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CKF48_RS07265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CKF48_RS07270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CKF48_RS07275	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CKF48_RS07285	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CKF48_RS07310	COG2252	PERMEase
CKF48_RS07325	COG1305	Transglutaminase-like
CKF48_RS07330	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CKF48_RS07335	COG0714	Associated with various cellular activities
CKF48_RS07340	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CKF48_RS07350	COG2304	oxidoreductase activity
CKF48_RS07370	COG2304	oxidoreductase activity
CKF48_RS07415	COG5444	nuclease activity
CKF48_RS07440	COG1511	domain protein
CKF48_RS07445	COG0433	COG0433 Predicted ATPase
CKF48_RS07445	COG1674	ftsk spoiiie
CKF48_RS07450	COG4499	WXG100 protein secretion system (Wss), protein YukC
CKF48_RS07455	COG5417	Belongs to the EsaB family
CKF48_RS07460	COG4842	Belongs to the WXG100 family
CKF48_RS07495	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS07505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CKF48_RS07510	COG1253	flavin adenine dinucleotide binding
CKF48_RS07515	COG1253	flavin adenine dinucleotide binding
CKF48_RS07525	COG2239	Acts as a magnesium transporter
CKF48_RS07530	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS07540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKF48_RS07560	COG0110	maltose O-acetyltransferase activity
CKF48_RS07575	COG3384	dioxygenase
CKF48_RS07580	COG2508	Transcriptional regulator
CKF48_RS07590	COG2146	nitrite reductase [NAD(P)H] activity
CKF48_RS07605	COG0583	DNA-binding transcription factor activity
CKF48_RS07695	COG3378	Phage plasmid primase P4 family
CKF48_RS07725	COG0582	viral genome integration into host DNA
CKF48_RS07730	COG0459	protein refolding
CKF48_RS07740	COG1266	CAAX protease self-immunity
CKF48_RS07750	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CKF48_RS07755	COG0315	cyclic pyranopterin monophosphate synthase activity
CKF48_RS07760	COG0488	(ABC) transporter
CKF48_RS07770	COG0456	acetyltransferase
CKF48_RS07775	COG1214	PFAM Peptidase M22, glycoprotease
CKF48_RS07780	COG0802	atpase or kinase
CKF48_RS07865	COG3091	SprT-like family
CKF48_RS07875	COG2183	response to ionizing radiation
CKF48_RS07880	COG2208	phosphoserine phosphatase activity
CKF48_RS07885	COG1191	sigma factor activity
CKF48_RS07890	COG2172	sigma factor antagonist activity
CKF48_RS07895	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS07900	COG2208	phosphoserine phosphatase activity
CKF48_RS07905	COG2172	sigma factor antagonist activity
CKF48_RS07910	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS07915	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS07920	COG2337	Toxic component of a toxin-antitoxin (TA) module
CKF48_RS07925	COG0864	Transcriptional regulator
CKF48_RS07935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CKF48_RS07940	COG0736	holo-[acyl-carrier-protein] synthase activity
CKF48_RS07945	COG0705	Rhomboid family
CKF48_RS07950	COG3428	Bacterial PH domain
CKF48_RS07955	COG3402	PFAM membrane-flanked domain
CKF48_RS07965	COG0513	Belongs to the DEAD box helicase family
CKF48_RS07975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CKF48_RS07980	COG1181	Belongs to the D-alanine--D-alanine ligase family
CKF48_RS08000	COG2096	Adenosyltransferase
CKF48_RS08015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CKF48_RS08020	COG1492	cobalamin metabolic process
CKF48_RS08035	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CKF48_RS08040	COG1120	ATPase activity
CKF48_RS08045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS08050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_RS08060	COG2239	Acts as a magnesium transporter
CKF48_RS08065	COG0772	Belongs to the SEDS family
CKF48_RS08070	COG0018	arginyl-trna synthetase
CKF48_RS08075	COG0730	response to heat
CKF48_RS08080	COG1238	metal cluster binding
CKF48_RS08085	COG0783	Belongs to the Dps family
CKF48_RS08100	COG3832	glyoxalase III activity
CKF48_RS08105	COG0640	Transcriptional regulator
CKF48_RS08125	COG4607	ABC-type enterochelin transport system periplasmic component
CKF48_RS08130	COG4604	ABC transporter, ATP-binding protein
CKF48_RS08135	COG4605	iron ion homeostasis
CKF48_RS08140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS08150	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS08155	COG0791	NLP P60 protein
CKF48_RS08160	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_RS08165	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKF48_RS08170	COG4166	transmembrane transport
CKF48_RS08175	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS08180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS08185	COG0601	transmembrane transport
CKF48_RS08190	COG2362	D-Aminopeptidase
CKF48_RS08200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CKF48_RS08215	COG0560	Phosphoserine phosphatase
CKF48_RS08220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKF48_RS08220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CKF48_RS08225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_RS08225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_RS08235	COG2514	catechol 2,3-dioxygenase activity
CKF48_RS08240	COG1733	regulation of RNA biosynthetic process
CKF48_RS08245	COG2427	Protein of unknown function (DUF1641)
CKF48_RS08250	COG3383	formate dehydrogenase (NAD+) activity
CKF48_RS08255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_RS08260	COG1271	oxidase subunit
CKF48_RS08265	COG1294	oxidase, subunit
CKF48_RS08275	COG2076	Multidrug Resistance protein
CKF48_RS08280	COG1309	transcriptional regulator
CKF48_RS08285	COG4191	Histidine kinase
CKF48_RS08295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKF48_RS08300	COG2706	6-phosphogluconolactonase activity
CKF48_RS08315	COG0488	(ABC) transporter
CKF48_RS08320	COG4555	ABC transporter
CKF48_RS08355	COG3942	CHAP domain
CKF48_RS08355	COG1705	Flagellar rod assembly protein muramidase FlgJ
CKF48_RS08380	COG2873	o-acetylhomoserine
CKF48_RS08395	COG1414	Transcriptional regulator
CKF48_RS08400	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_RS08415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CKF48_RS08420	COG2814	Major facilitator Superfamily
CKF48_RS08445	COG1216	Glycosyl transferase, family 2
CKF48_RS08450	COG1086	Polysaccharide biosynthesis protein
CKF48_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS08465	COG0463	Glycosyl transferase, family 2
CKF48_RS08470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CKF48_RS08480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CKF48_RS08485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CKF48_RS08490	COG0590	tRNA wobble adenosine to inosine editing
CKF48_RS08505	COG1266	CAAX protease self-immunity
CKF48_RS08510	COG4978	Transcriptional regulator
CKF48_RS08510	COG0789	Transcriptional regulator
CKF48_RS08515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CKF48_RS08520	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_RS08530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_RS08540	COG0753	catalase activity
CKF48_RS08540	COG0693	protein deglycase activity
CKF48_RS08560	COG1414	Transcriptional regulator
CKF48_RS08565	COG2271	Major facilitator Superfamily
CKF48_RS08575	COG2267	carboxylic ester hydrolase activity
CKF48_RS08585	COG0196	riboflavin kinase activity
CKF48_RS08595	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS08615	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKF48_RS08630	COG1368	sulfuric ester hydrolase activity
CKF48_RS08635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CKF48_RS08640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKF48_RS08650	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS08665	COG5002	protein histidine kinase activity
CKF48_RS08665	COG3850	Histidine kinase
CKF48_RS08670	COG0745	RESPONSE REGULATOR receiver
CKF48_RS08690	COG1301	dicarboxylic acid transport
CKF48_RS08705	COG2814	Major facilitator Superfamily
CKF48_RS08765	COG0785	Cytochrome C biogenesis protein
CKF48_RS08775	COG0500	methyltransferase
CKF48_RS08780	COG0561	phosphatase activity
CKF48_RS08795	COG2855	membrane
CKF48_RS08800	COG0583	DNA-binding transcription factor activity
CKF48_RS08805	COG3708	Transcriptional regulator
CKF48_RS08805	COG2207	Transcriptional regulator
CKF48_RS08810	COG3973	AAA domain
CKF48_RS08815	COG3973	AAA domain
CKF48_RS08835	COG3859	Proton-coupled thiamine transporter YuaJ
CKF48_RS08845	COG1595	DNA-templated transcription, initiation
CKF48_RS08860	COG0393	Putative heavy-metal-binding
CKF48_RS08885	COG1027	Aspartate ammonia-lyase
CKF48_RS08905	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS08910	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS08925	COG0135	phosphoribosylanthranilate isomerase activity
CKF48_RS08970	COG2226	methyltransferase
CKF48_RS09025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CKF48_RS09050	COG1053	succinate dehydrogenase
CKF48_RS09060	COG0583	DNA-binding transcription factor activity
CKF48_RS09115	COG1131	(ABC) transporter
CKF48_RS09120	COG2205	protein histidine kinase activity
CKF48_RS09125	COG0745	RESPONSE REGULATOR receiver
CKF48_RS09130	COG0656	L-ascorbic acid biosynthetic process
CKF48_RS09135	COG2814	Major facilitator Superfamily
CKF48_RS09140	COG1733	regulation of RNA biosynthetic process
CKF48_RS09145	COG3620	sequence-specific DNA binding
CKF48_RS09155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_RS09160	COG1279	arginine transmembrane transporter activity
CKF48_RS09165	COG0572	uridine kinase
CKF48_RS09180	COG1595	DNA-templated transcription, initiation
CKF48_RS09185	COG1476	TRANSCRIPTIONal
CKF48_RS09205	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CKF48_RS09210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CKF48_RS09215	COG4856	YbbR-like protein
CKF48_RS09220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CKF48_RS09225	COG5662	AntiSigma factor
CKF48_RS09230	COG1595	DNA-templated transcription, initiation
CKF48_RS09305	COG0726	polysaccharide deacetylase
CKF48_RS09310	COG2194	sulfuric ester hydrolase activity
CKF48_RS09320	COG0489	protein tyrosine kinase activity
CKF48_RS09325	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_RS09335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_RS09385	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS09405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CKF48_RS09410	COG1131	(ABC) transporter
CKF48_RS09430	COG1595	DNA-templated transcription, initiation
CKF48_RS09435	COG0745	RESPONSE REGULATOR receiver
CKF48_RS09440	COG2205	protein histidine kinase activity
CKF48_RS09445	COG2814	Major facilitator Superfamily
CKF48_RS09450	COG1131	(ABC) transporter
CKF48_RS09510	COG4974	Belongs to the 'phage' integrase family
CKF48_RS09590	COG1136	(ABC) transporter
CKF48_RS09620	COG2003	Belongs to the UPF0758 family
CKF48_RS09785	COG5484	DNA packaging
CKF48_RS09810	COG3677	Transposase
CKF48_RS09885	COG1484	DNA-dependent DNA replication
CKF48_RS09895	COG3723	Recombinational DNA repair protein, rece pathway
CKF48_RS09900	COG5377	YqaJ viral recombinase family
CKF48_RS09915	COG3645	SOS response
CKF48_RS09915	COG3646	Phage regulatory protein
CKF48_RS09935	COG1396	sequence-specific DNA binding
CKF48_RS09950	COG0582	viral genome integration into host DNA
CKF48_RS09955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CKF48_RS09960	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CKF48_RS09970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKF48_RS09975	COG1122	ATPase activity
CKF48_RS09980	COG1122	ATPase activity
CKF48_RS09990	COG0203	ribosomal protein L17
CKF48_RS09995	COG0202	RNA polymerase activity
CKF48_RS10010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CKF48_RS10015	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CKF48_RS10020	COG0024	Methionine aminopeptidase
CKF48_RS10025	COG0563	adenylate kinase activity
CKF48_RS10030	COG0201	protein transport
CKF48_RS10040	COG1841	ribosomal large subunit assembly
CKF48_RS10045	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CKF48_RS10050	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CKF48_RS10055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CKF48_RS10070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CKF48_RS10075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CKF48_RS10080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CKF48_RS10095	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CKF48_RS10100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CKF48_RS10110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CKF48_RS10115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CKF48_RS10125	COG0088	Forms part of the polypeptide exit tunnel
CKF48_RS10130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CKF48_RS10135	COG0051	transcription antitermination factor activity, RNA binding
CKF48_RS10140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CKF48_RS10140	COG0646	methionine synthase
CKF48_RS10145	COG0646	methionine synthase
CKF48_RS10145	COG1410	methionine synthase
CKF48_RS10150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CKF48_RS10155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CKF48_RS10165	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CKF48_RS10170	COG1358	cellular component organization or biogenesis
CKF48_RS10175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CKF48_RS10180	COG0085	RNA polymerase activity
CKF48_RS10185	COG2813	Specifically methylates the guanine in position
CKF48_RS10195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CKF48_RS10200	COG0081	regulation of translation
CKF48_RS10205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CKF48_RS10210	COG0250	Participates in transcription elongation, termination and antitermination
CKF48_RS10215	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKF48_RS10230	COG3688	RNA-binding protein containing a PIN domain
CKF48_RS10235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKF48_RS10245	COG0215	cysteine-tRNA ligase activity
CKF48_RS10250	COG1045	serine acetyltransferase
CKF48_RS10255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CKF48_RS10260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CKF48_RS10265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CKF48_RS10270	COG4956	integral membrane protein (PIN domain superfamily)
CKF48_RS10280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CKF48_RS10285	COG0542	response to heat
CKF48_RS10290	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CKF48_RS10295	COG3880	PFAM UvrB UvrC protein
CKF48_RS10390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CKF48_RS10395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CKF48_RS10400	COG1396	sequence-specific DNA binding
CKF48_RS10405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CKF48_RS10410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CKF48_RS10415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CKF48_RS10420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CKF48_RS10425	COG0512	Glutamine amidotransferase of anthranilate synthase
CKF48_RS10430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CKF48_RS10435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_RS10440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CKF48_RS10445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CKF48_RS10450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CKF48_RS10455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKF48_RS10460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CKF48_RS10470	COG0515	serine threonine protein kinase
CKF48_RS10475	COG2304	oxidoreductase activity
CKF48_RS10480	COG2208	phosphoserine phosphatase activity
CKF48_RS10495	COG1098	S1 RNA binding domain
CKF48_RS10500	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CKF48_RS10515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CKF48_RS10520	COG3956	TIGRFAM MazG family protein
CKF48_RS10525	COG2244	polysaccharide biosynthetic process
CKF48_RS10530	COG2002	toxin-antitoxin pair type II binding
CKF48_RS10560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CKF48_RS10570	COG0251	oxidation-reduction process
CKF48_RS10575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKF48_RS10590	COG4466	Protein conserved in bacteria
CKF48_RS10600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CKF48_RS10610	COG3584	3D domain protein
CKF48_RS10610	COG3583	domain protein
CKF48_RS10615	COG0084	hydrolase, TatD family'
CKF48_RS10630	COG2002	toxin-antitoxin pair type II binding
CKF48_RS10635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CKF48_RS10640	COG2827	Endonuclease containing a URI domain
CKF48_RS10645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CKF48_RS10650	COG4467	Involved in initiation control of chromosome replication
CKF48_RS10655	COG1774	PSP1 C-terminal conserved region
CKF48_RS10660	COG0470	DNA polymerase III
CKF48_RS10665	COG1728	Protein conserved in bacteria
CKF48_RS10670	COG3870	Protein conserved in bacteria
CKF48_RS10675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CKF48_RS10680	COG1982	Orn Lys Arg decarboxylase major
CKF48_RS10715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CKF48_RS10720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CKF48_RS10725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CKF48_RS10735	COG0590	tRNA wobble adenosine to inosine editing
CKF48_RS10740	COG1335	isochorismatase
CKF48_RS10745	COG1388	LysM domain
CKF48_RS10745	COG3858	chitin binding
CKF48_RS10750	COG1428	Deoxynucleoside kinase
CKF48_RS10755	COG1428	Deoxynucleoside kinase
CKF48_RS10765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CKF48_RS10775	COG0516	GMP reductase activity
CKF48_RS10775	COG0517	IMP dehydrogenase activity
CKF48_RS10810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CKF48_RS10815	COG0187	DNA topoisomerase II activity
CKF48_RS10830	COG2501	S4 domain
CKF48_RS10835	COG0592	DNA-directed DNA polymerase activity
CKF48_RS10845	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CKF48_RS10850	COG0594	ribonuclease P activity
CKF48_RS10855	COG0706	membrane insertase activity
CKF48_RS10860	COG1847	R3H domain protein
CKF48_RS10865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CKF48_RS10875	COG0357	Ribosomal RNA small subunit methyltransferase G
CKF48_RS10880	COG1475	DNA binding
CKF48_RS10885	COG1192	Involved in chromosome partitioning
CKF48_RS10890	COG1475	DNA binding
CKF48_RS10905	COG4481	Protein conserved in bacteria
CKF48_RS10910	COG0012	GTP binding
CKF48_RS10915	COG0360	Binds together with S18 to 16S ribosomal RNA
CKF48_RS10925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CKF48_RS10945	COG4241	membrane
CKF48_RS10950	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CKF48_RS10955	COG0359	binds to the 23S rRNA
CKF48_RS10960	COG0305	Participates in initiation and elongation during chromosome replication
CKF48_RS10965	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CKF48_RS11000	COG0739	heme binding
CKF48_RS11000	COG0741	lytic transglycosylase activity
CKF48_RS11000	COG1196	nuclear chromosome segregation
CKF48_RS11005	COG0745	RESPONSE REGULATOR receiver
CKF48_RS11010	COG5002	protein histidine kinase activity
CKF48_RS11020	COG4853	Protein conserved in bacteria
CKF48_RS11025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CKF48_RS11030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKF48_RS11055	COG1595	DNA-templated transcription, initiation
CKF48_RS11060	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CKF48_RS11070	COG5002	protein histidine kinase activity
CKF48_RS11075	COG0745	RESPONSE REGULATOR receiver
CKF48_RS11080	COG0666	response to abiotic stimulus
CKF48_RS11090	COG0778	Nitroreductase
CKF48_RS11095	COG4978	Transcriptional regulator
CKF48_RS11095	COG0789	Transcriptional regulator
CKF48_RS11115	COG0494	nUDIX hydrolase
CKF48_RS11125	COG5444	nuclease activity
CKF48_RS11160	COG1187	pseudouridine synthase activity
CKF48_RS11185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_RS11215	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CKF48_RS11240	COG0745	RESPONSE REGULATOR receiver
CKF48_RS11245	COG1136	(ABC) transporter
CKF48_RS11250	COG0577	efflux transmembrane transporter activity
CKF48_RS11265	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS11270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_RS11280	COG1464	Belongs to the NlpA lipoprotein family
CKF48_RS11295	COG1070	Carbohydrate kinase
CKF48_RS11315	COG1115	amino acid carrier protein
CKF48_RS11320	COG2202	Pas domain
CKF48_RS11320	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS11330	COG3835	regulator
CKF48_RS11335	COG1929	Belongs to the glycerate kinase type-1 family
CKF48_RS11345	COG0583	DNA-binding transcription factor activity
CKF48_RS11355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CKF48_RS11360	COG1984	allophanate hydrolase subunit 2
CKF48_RS11365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CKF48_RS11370	COG1914	H( )-stimulated, divalent metal cation uptake system
CKF48_RS11375	COG4336	lyase activity
CKF48_RS11395	COG0745	RESPONSE REGULATOR receiver
CKF48_RS11405	COG1280	lysine exporter protein (LysE YggA)
CKF48_RS11425	COG0840	transmembrane signaling receptor activity
CKF48_RS11425	COG3290	protein histidine kinase activity
CKF48_RS11430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_RS11435	COG0765	amino acid transport
CKF48_RS11440	COG1126	abc transporter atp-binding protein
CKF48_RS11450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CKF48_RS11455	COG0778	Nitroreductase
CKF48_RS11460	COG4536	flavin adenine dinucleotide binding
CKF48_RS11465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_RS11470	COG0577	efflux transmembrane transporter activity
CKF48_RS11475	COG1136	(ABC) transporter
CKF48_RS11480	COG0642	Histidine kinase
CKF48_RS11485	COG0745	RESPONSE REGULATOR receiver
CKF48_RS11490	COG2329	Antibiotic biosynthesis monooxygenase
CKF48_RS11520	COG3627	carbon phosphorus lyase activity
CKF48_RS11525	COG4107	phosphonate C-P lyase system protein PhnK
CKF48_RS11530	COG3454	Phosphonate metabolism
CKF48_RS11535	COG4778	phosphonate C-P lyase system protein PhnL
CKF48_RS11540	COG0613	PHP domain protein
CKF48_RS11550	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CKF48_RS11555	COG3639	organic phosphonate transmembrane transporter activity
CKF48_RS11560	COG3639	organic phosphonate transmembrane transporter activity
CKF48_RS11565	COG2814	Major facilitator Superfamily
CKF48_RS11570	COG0477	Major facilitator Superfamily
CKF48_RS11580	COG3104	oligopeptide transport
CKF48_RS11600	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS11605	COG0366	Alpha amylase catalytic
CKF48_RS11610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CKF48_RS11620	COG3314	Sporulation integral membrane protein YlbJ
CKF48_RS11635	COG4555	ABC transporter
CKF48_RS11640	COG1132	(ABC) transporter
CKF48_RS11650	COG2031	fatty acid transporter
CKF48_RS11665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CKF48_RS11670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CKF48_RS11675	COG0351	phosphomethylpyrimidine kinase
CKF48_RS11690	COG0746	molybdenum cofactor guanylyltransferase activity
CKF48_RS11695	COG0314	molybdopterin synthase activity
CKF48_RS11700	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CKF48_RS11705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CKF48_RS11710	COG1522	sequence-specific DNA binding
CKF48_RS11715	COG0601	transmembrane transport
CKF48_RS11720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS11730	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS11735	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS11740	COG0405	Gamma-glutamyltransferase
CKF48_RS11745	COG2059	Chromate
CKF48_RS11750	COG2059	Chromate
CKF48_RS11760	COG3852	Histidine kinase
CKF48_RS11780	COG3842	ATPase activity
CKF48_RS11785	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKF48_RS11820	COG0577	efflux transmembrane transporter activity
CKF48_RS11825	COG1136	(ABC) transporter
CKF48_RS11825	COG0577	efflux transmembrane transporter activity
CKF48_RS11835	COG0475	glutathione-regulated potassium exporter activity
CKF48_RS11845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CKF48_RS11860	COG0165	Argininosuccinate lyase
CKF48_RS11870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_RS11890	COG2197	response regulator
CKF48_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS11915	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS11925	COG0028	Belongs to the TPP enzyme family
CKF48_RS11930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_RS11935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CKF48_RS11940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CKF48_RS11945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CKF48_RS11960	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CKF48_RS11975	COG2363	Small membrane protein
CKF48_RS11985	COG3773	Cell wall hydrolase
CKF48_RS11990	COG3253	May function as heme-dependent peroxidase
CKF48_RS11995	COG0280	phosphate acetyltransferase
CKF48_RS12015	COG1078	dGTPase activity
CKF48_RS12020	COG3465	dGTPase activity
CKF48_RS12040	COG1994	Peptidase M50
CKF48_RS12050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKF48_RS12055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CKF48_RS12060	COG0010	Belongs to the arginase family
CKF48_RS12065	COG4506	Protein conserved in bacteria
CKF48_RS12070	COG0018	arginyl-trna synthetase
CKF48_RS12085	COG4294	response to UV
CKF48_RS12090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKF48_RS12095	COG2181	nitrate reductase activity
CKF48_RS12095	COG0247	lactate metabolic process
CKF48_RS12100	COG0183	Belongs to the thiolase family
CKF48_RS12105	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_RS12110	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS12115	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS12125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_RS12125	COG1703	isobutyryl-CoA mutase activity
CKF48_RS12125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_RS12135	COG0504	CTP synthase activity
CKF48_RS12140	COG4821	SIS domain
CKF48_RS12145	COG2204	response regulator
CKF48_RS12150	COG0191	fructose-bisphosphate aldolase activity
CKF48_RS12155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CKF48_RS12160	COG1494	fructose-1,6-bisphosphatase
CKF48_RS12165	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CKF48_RS12175	COG1435	thymidine kinase activity
CKF48_RS12185	COG0697	spore germination
CKF48_RS12190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CKF48_RS12210	COG0009	L-threonylcarbamoyladenylate synthase
CKF48_RS12220	COG1971	Probably functions as a manganese efflux pump
CKF48_RS12230	COG0840	transmembrane signaling receptor activity
CKF48_RS12235	COG0698	ribose 5-phosphate isomerase
CKF48_RS12240	COG4475	Protein of unknown function (DUF436)
CKF48_RS12250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CKF48_RS12255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CKF48_RS12260	COG1404	Belongs to the peptidase S8 family
CKF48_RS12275	COG0356	it plays a direct role in the translocation of protons across the membrane
CKF48_RS12280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKF48_RS12285	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CKF48_RS12290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CKF48_RS12295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CKF48_RS12300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CKF48_RS12305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CKF48_RS12310	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CKF48_RS12315	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_RS12320	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_RS12325	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_RS12330	COG0649	NAD binding
CKF48_RS12340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CKF48_RS12345	COG0839	Belongs to the complex I subunit 6 family
CKF48_RS12350	COG0713	ATP synthesis coupled electron transport
CKF48_RS12355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CKF48_RS12365	COG1007	ATP synthesis coupled electron transport
CKF48_RS12370	COG4836	Membrane
CKF48_RS12385	COG2385	sporulation resulting in formation of a cellular spore
CKF48_RS12390	COG0739	heme binding
CKF48_RS12395	COG1388	LysM domain
CKF48_RS12395	COG0791	NLP P60 protein
CKF48_RS12400	COG1609	Transcriptional regulator
CKF48_RS12405	COG1077	Cell shape determining protein MreB Mrl
CKF48_RS12410	COG4786	Flagellar basal body rod
CKF48_RS12415	COG4786	Flagellar basal body rod
CKF48_RS12445	COG0629	single-stranded DNA binding
CKF48_RS12465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKF48_RS12485	COG3739	integral membrane protein
CKF48_RS12535	COG2851	Citrate transporter
CKF48_RS12540	COG4565	transcriptional regulatory protein
CKF48_RS12545	COG4565	transcriptional regulatory protein
CKF48_RS12550	COG3290	protein histidine kinase activity
CKF48_RS12555	COG1959	2 iron, 2 sulfur cluster binding
CKF48_RS12560	COG2910	NAD(P)H-binding
CKF48_RS12565	COG0592	DNA-directed DNA polymerase activity
CKF48_RS12590	COG0791	NLP P60 protein
CKF48_RS12590	COG1388	LysM domain
CKF48_RS12605	COG1054	Belongs to the UPF0176 family
CKF48_RS12630	COG0534	Mate efflux family protein
CKF48_RS12635	COG0768	penicillin binding
CKF48_RS12650	COG1929	Belongs to the glycerate kinase type-1 family
CKF48_RS12660	COG1335	isochorismatase
CKF48_RS12680	COG2188	Transcriptional regulator
CKF48_RS12695	COG0640	Transcriptional regulator
CKF48_RS12700	COG0697	spore germination
CKF48_RS12720	COG2011	ABC-type metal ion transport system permease component
CKF48_RS12725	COG1464	Belongs to the NlpA lipoprotein family
CKF48_RS12735	COG0667	Aldo Keto reductase
CKF48_RS12740	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS12745	COG1473	amidohydrolase
CKF48_RS12755	COG0747	negative chemotaxis
CKF48_RS12760	COG0601	transmembrane transport
CKF48_RS12770	COG0444	Belongs to the ABC transporter superfamily
CKF48_RS12775	COG4608	Belongs to the ABC transporter superfamily
CKF48_RS12780	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_RS12790	COG0488	(ABC) transporter
CKF48_RS12795	COG3279	Response regulator of the LytR AlgR family
CKF48_RS12825	COG2851	Citrate transporter
CKF48_RS12830	COG3290	protein histidine kinase activity
CKF48_RS12830	COG3829	transcription factor binding
CKF48_RS12850	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_RS12855	COG0583	DNA-binding transcription factor activity
CKF48_RS12860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CKF48_RS12865	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS12890	COG2031	fatty acid transporter
CKF48_RS12895	COG4172	Belongs to the ABC transporter superfamily
CKF48_RS12900	COG0601	transmembrane transport
CKF48_RS12905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS12935	COG4682	membrane
CKF48_RS12960	COG1695	Transcriptional regulator
CKF48_RS12965	COG1830	Aldolase
CKF48_RS12975	COG3775	system Galactitol-specific IIC component
CKF48_RS12980	COG1070	Carbohydrate kinase
CKF48_RS12985	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS12990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_RS13000	COG1366	Belongs to the anti-sigma-factor antagonist family
CKF48_RS13005	COG1278	Cold shock
CKF48_RS13010	COG1120	ATPase activity
CKF48_RS13015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS13020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS13025	COG4607	ABC-type enterochelin transport system periplasmic component
CKF48_RS13035	COG1454	alcohol dehydrogenase
CKF48_RS13040	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS13045	COG0659	secondary active sulfate transmembrane transporter activity
CKF48_RS13050	COG1609	Transcriptional regulator
CKF48_RS13080	COG0386	Belongs to the glutathione peroxidase family
CKF48_RS13085	COG1846	Transcriptional regulator
CKF48_RS13105	COG1846	Transcriptional regulator
CKF48_RS13115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS13120	COG0406	alpha-ribazole phosphatase activity
CKF48_RS13140	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS13150	COG1126	abc transporter atp-binding protein
CKF48_RS13155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_RS13160	COG0765	amino acid transport
CKF48_RS13165	COG0765	amino acid transport
CKF48_RS13170	COG1695	Transcriptional regulator
CKF48_RS13190	COG1473	amidohydrolase
CKF48_RS13205	COG2610	gluconate transmembrane transporter activity
CKF48_RS13210	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS13225	COG1742	UPF0060 membrane protein
CKF48_RS13240	COG0154	amidase activity
CKF48_RS13265	COG0778	Nitroreductase
CKF48_RS13270	COG1733	regulation of RNA biosynthetic process
CKF48_RS13280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKF48_RS13300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CKF48_RS13310	COG2843	Capsule synthesis protein
CKF48_RS13320	COG3562	capsule polysaccharide
CKF48_RS13325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKF48_RS13330	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKF48_RS13335	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CKF48_RS13335	COG0517	IMP dehydrogenase activity
CKF48_RS13340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKF48_RS13365	COG3562	capsule polysaccharide
CKF48_RS13370	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CKF48_RS13375	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CKF48_RS13385	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CKF48_RS13410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKF48_RS13420	COG1682	transport, permease protein
CKF48_RS13430	COG1134	teichoic acid transport
CKF48_RS13440	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_RS13445	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CKF48_RS13450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_RS13455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CKF48_RS13460	COG1215	transferase activity, transferring glycosyl groups
CKF48_RS13460	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_RS13465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_RS13470	COG5263	repeat protein
CKF48_RS13470	COG4193	domain, Protein
CKF48_RS13480	COG0728	peptidoglycan biosynthetic process
CKF48_RS13490	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS13495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CKF48_RS13510	COG1739	Uncharacterized protein family UPF0029
CKF48_RS13515	COG4585	Histidine kinase
CKF48_RS13525	COG1307	EDD domain protein, DegV family
CKF48_RS13530	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CKF48_RS13535	COG1040	competence protein
CKF48_RS13545	COG2747	anti-sigma28 factor FlgM
CKF48_RS13555	COG1256	bacterial-type flagellum assembly
CKF48_RS13555	COG4786	Flagellar basal body rod
CKF48_RS13560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CKF48_RS13570	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CKF48_RS13575	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CKF48_RS13585	COG1334	flagellar protein FlaG
CKF48_RS13590	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CKF48_RS13595	COG1516	flagellar protein fliS
CKF48_RS13630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CKF48_RS13640	COG1175	transmembrane transport
CKF48_RS13650	COG3842	ATPase activity
CKF48_RS13665	COG1405	negative regulation of cell septum assembly
CKF48_RS13665	COG3012	SEC-C Motif Domain Protein
CKF48_RS13670	COG0653	protein targeting
CKF48_RS13690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_RS13700	COG2884	Cell division ATP-binding protein ftsE
CKF48_RS13705	COG2177	Part of the ABC transporter FtsEX involved in
CKF48_RS13710	COG0739	heme binding
CKF48_RS13715	COG0793	Belongs to the peptidase S41A family
CKF48_RS13715	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_RS13720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CKF48_RS13725	COG0488	(ABC) transporter
CKF48_RS13730	COG1846	Transcriptional regulator
CKF48_RS13735	COG0346	lactoylglutathione lyase activity
CKF48_RS13740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKF48_RS13745	COG0400	carboxylic ester hydrolase activity
CKF48_RS13755	COG0655	NAD(P)H dehydrogenase (quinone) activity
CKF48_RS13760	COG0628	permease
CKF48_RS13770	COG0556	nucleotide-excision repair
CKF48_RS13775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CKF48_RS13785	COG3595	metallopeptidase activity
CKF48_RS13790	COG1950	PFAM Membrane protein of
CKF48_RS13795	COG1309	transcriptional regulator
CKF48_RS13805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CKF48_RS13810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CKF48_RS13820	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CKF48_RS13830	COG0110	maltose O-acetyltransferase activity
CKF48_RS13835	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CKF48_RS13840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CKF48_RS13845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CKF48_RS13850	COG0131	Imidazoleglycerol-phosphate dehydratase
CKF48_RS13855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CKF48_RS13860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CKF48_RS13865	COG0107	imidazoleglycerol-phosphate synthase activity
CKF48_RS13870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CKF48_RS13870	COG0140	phosphoribosyl-ATP diphosphatase activity
CKF48_RS13875	COG0457	Tetratricopeptide repeat
CKF48_RS13880	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS13890	COG1051	belongs to the nudix hydrolase family
CKF48_RS13895	COG1660	Displays ATPase and GTPase activities
CKF48_RS13900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CKF48_RS13910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKF48_RS13920	COG0740	serine-type endopeptidase activity
CKF48_RS13955	COG1404	Belongs to the peptidase S8 family
CKF48_RS14015	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CKF48_RS14020	COG1647	Serine aminopeptidase, S33
CKF48_RS14025	COG0557	exoribonuclease II activity
CKF48_RS14030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CKF48_RS14045	COG0346	lactoylglutathione lyase activity
CKF48_RS14050	COG0640	Transcriptional regulator
CKF48_RS14055	COG0640	Transcriptional regulator
CKF48_RS14060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CKF48_RS14065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CKF48_RS14080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CKF48_RS14085	COG2030	dehydratase
CKF48_RS14095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_RS14105	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS14125	COG0586	Pfam SNARE associated Golgi protein
CKF48_RS14130	COG2814	Major facilitator Superfamily
CKF48_RS14140	COG1733	regulation of RNA biosynthetic process
CKF48_RS14145	COG0693	protein deglycase activity
CKF48_RS14150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_RS14155	COG0765	amino acid transport
CKF48_RS14160	COG1126	abc transporter atp-binding protein
CKF48_RS14185	COG2816	NAD+ diphosphatase activity
CKF48_RS14190	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS14195	COG4149	molybdate abc transporter
CKF48_RS14200	COG0725	ABC transporter, periplasmic molybdate-binding protein
CKF48_RS14205	COG3842	ATPase activity
CKF48_RS14210	COG1910	domain protein
CKF48_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS14235	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_RS14240	COG3829	transcription factor binding
CKF48_RS14240	COG3290	protein histidine kinase activity
CKF48_RS14245	COG2610	gluconate transmembrane transporter activity
CKF48_RS14250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CKF48_RS14255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CKF48_RS14260	COG1309	transcriptional regulator
CKF48_RS14265	COG1033	growth of symbiont in host cell
CKF48_RS14265	COG2409	Drug exporters of the RND superfamily
CKF48_RS14270	COG2011	ABC-type metal ion transport system permease component
CKF48_RS14275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_RS14280	COG1464	Belongs to the NlpA lipoprotein family
CKF48_RS14285	COG0371	Dehydrogenase
CKF48_RS14310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CKF48_RS14325	COG0668	transmembrane transport
CKF48_RS14330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CKF48_RS14345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_RS14350	COG4597	amino acid ABC transporter
CKF48_RS14355	COG0765	amino acid transport
CKF48_RS14360	COG1126	abc transporter atp-binding protein
CKF48_RS14510	COG0772	Belongs to the SEDS family
CKF48_RS14535	COG5577	PFAM Coat F domain
CKF48_RS14545	COG1024	Enoyl-CoA hydratase
CKF48_RS14545	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_RS14550	COG0183	Belongs to the thiolase family
CKF48_RS14555	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS14560	COG1393	Belongs to the ArsC family
CKF48_RS14565	COG0509	glycine decarboxylation via glycine cleavage system
CKF48_RS14570	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CKF48_RS14575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_RS14585	COG2873	o-acetylhomoserine
CKF48_RS14590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CKF48_RS14595	COG2011	ABC-type metal ion transport system permease component
CKF48_RS14600	COG1464	Belongs to the NlpA lipoprotein family
CKF48_RS14605	COG0396	ATPase activity
CKF48_RS14610	COG0719	Fe-S assembly protein
CKF48_RS14615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CKF48_RS14620	COG0822	iron-sulfur transferase activity
CKF48_RS14625	COG0719	Fe-S assembly protein
CKF48_RS14630	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_RS14630	COG5632	N-Acetylmuramoyl-L-alanine amidase
CKF48_RS14635	COG1309	transcriptional regulator
CKF48_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS14645	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CKF48_RS14660	COG1801	Protein of unknown function DUF72
CKF48_RS14665	COG3377	Domain of unknown function (DUF1805)
CKF48_RS14670	COG1757	Na H antiporter
CKF48_RS14680	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS14690	COG0411	ABC transporter
CKF48_RS14700	COG0739	heme binding
CKF48_RS14705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CKF48_RS14715	COG4470	Protein conserved in bacteria
CKF48_RS14730	COG2445	Protein of unknown function DUF86
CKF48_RS14735	COG0647	UMP catabolic process
CKF48_RS14740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CKF48_RS14745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CKF48_RS14755	COG1349	DNA-binding transcription factor activity
CKF48_RS14765	COG0460	homoserine dehydrogenase
CKF48_RS14770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CKF48_RS14775	COG0083	homoserine kinase activity
CKF48_RS14780	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CKF48_RS14785	COG4837	Protein of unknown function (DUF1462)
CKF48_RS14790	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CKF48_RS14815	COG1252	NADH dehydrogenase
CKF48_RS14825	COG0316	Belongs to the HesB IscA family
CKF48_RS14835	COG1252	NADH dehydrogenase
CKF48_RS14845	COG1802	Transcriptional regulator
CKF48_RS14880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKF48_RS14900	COG3584	3D domain protein
CKF48_RS14905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CKF48_RS14910	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CKF48_RS14915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CKF48_RS14920	COG2056	Na+-H+ antiporter family
CKF48_RS14925	COG0789	Transcriptional regulator
CKF48_RS14935	COG1115	amino acid carrier protein
CKF48_RS14940	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CKF48_RS14940	COG2508	Transcriptional regulator
CKF48_RS14945	COG0686	Belongs to the AlaDH PNT family
CKF48_RS14950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKF48_RS14975	COG2050	protein possibly involved in aromatic compounds catabolism
CKF48_RS14980	COG1320	monovalent cation:proton antiporter activity
CKF48_RS14985	COG2212	antiporter activity
CKF48_RS14990	COG1863	multisubunit Na H antiporter MnhE subunit
CKF48_RS14995	COG0651	ATP synthesis coupled electron transport
CKF48_RS15000	COG1006	Multisubunit Na H antiporter MnhC subunit
CKF48_RS15005	COG2111	Na H antiporter
CKF48_RS15010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CKF48_RS15010	COG2111	Na H antiporter
CKF48_RS15020	COG5018	Exonuclease
CKF48_RS15030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKF48_RS15040	COG2032	superoxide dismutase activity
CKF48_RS15050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CKF48_RS15060	COG2267	carboxylic ester hydrolase activity
CKF48_RS15070	COG1098	S1 RNA binding domain
CKF48_RS15075	COG1979	alcohol dehydrogenase
CKF48_RS15085	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CKF48_RS15120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CKF48_RS15125	COG0702	epimerase
CKF48_RS15130	COG2356	endonuclease I
CKF48_RS15160	COG3944	biosynthesis protein
CKF48_RS15165	COG0489	protein tyrosine kinase activity
CKF48_RS15170	COG1086	Polysaccharide biosynthesis protein
CKF48_RS15175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CKF48_RS15180	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS15185	COG1442	glycosyl transferase family 8
CKF48_RS15185	COG1216	Glycosyl transferase, family 2
CKF48_RS15190	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS15195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CKF48_RS15195	COG0463	Glycosyl transferase, family 2
CKF48_RS15205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CKF48_RS15210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CKF48_RS15220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CKF48_RS15225	COG1396	sequence-specific DNA binding
CKF48_RS15240	COG1216	Glycosyl transferase, family 2
CKF48_RS15275	COG1132	(ABC) transporter
CKF48_RS15295	COG0463	Glycosyl transferase, family 2
CKF48_RS15295	COG0457	Tetratricopeptide repeat
CKF48_RS15345	COG1733	regulation of RNA biosynthetic process
CKF48_RS15360	COG1959	2 iron, 2 sulfur cluster binding
CKF48_RS15365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CKF48_RS15385	COG1285	pathogenesis
CKF48_RS15525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CKF48_RS15530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CKF48_RS15535	COG0297	glycogen (starch) synthase activity
CKF48_RS15540	COG0058	SHG alpha-glucan phosphorylase activity
CKF48_RS15545	COG1834	amidinotransferase
CKF48_RS15550	COG1575	Belongs to the MenA family. Type 1 subfamily
CKF48_RS15555	COG1169	isochorismate synthase
CKF48_RS15560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CKF48_RS15565	COG0596	Alpha beta hydrolase
CKF48_RS15570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CKF48_RS15575	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS15600	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKF48_RS15600	COG3443	Belongs to the bacterial solute-binding protein 9 family
CKF48_RS15605	COG0288	reversible hydration of carbon dioxide
CKF48_RS15610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CKF48_RS15625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CKF48_RS15635	COG0783	Belongs to the Dps family
CKF48_RS15650	COG0494	nUDIX hydrolase
CKF48_RS15655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_RS15660	COG1116	anion transmembrane transporter activity
CKF48_RS15665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_RS15670	COG1506	peptidase
CKF48_RS15680	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CKF48_RS15685	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CKF48_RS15690	COG0367	asparagine synthase
CKF48_RS15695	COG4990	cell redox homeostasis
CKF48_RS15700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CKF48_RS15705	COG2267	carboxylic ester hydrolase activity
CKF48_RS15715	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CKF48_RS15720	COG1242	4 iron, 4 sulfur cluster binding
CKF48_RS15735	COG2814	Major facilitator Superfamily
CKF48_RS15745	COG0495	leucyl-tRNA aminoacylation
CKF48_RS15750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_RS15770	COG1131	(ABC) transporter
CKF48_RS15800	COG2244	polysaccharide biosynthetic process
CKF48_RS15810	COG2851	Citrate transporter
CKF48_RS15815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_RS15820	COG2186	Transcriptional regulator
CKF48_RS15835	COG1187	pseudouridine synthase activity
CKF48_RS15840	COG1349	DNA-binding transcription factor activity
CKF48_RS15845	COG1125	glycine betaine transport
CKF48_RS15845	COG0517	IMP dehydrogenase activity
CKF48_RS15850	COG1174	glycine betaine transport
CKF48_RS15855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKF48_RS15865	COG0628	permease
CKF48_RS15885	COG1289	transmembrane transporter activity
CKF48_RS15890	COG0753	catalase activity
CKF48_RS15900	COG0477	Major facilitator Superfamily
CKF48_RS15910	COG2814	Major facilitator Superfamily
CKF48_RS15915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_RS15930	COG1523	belongs to the glycosyl hydrolase 13 family
CKF48_RS15935	COG0510	thiamine kinase activity
CKF48_RS15945	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CKF48_RS15950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS15960	COG1363	Peptidase, m42
CKF48_RS15965	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CKF48_RS15980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_RS15985	COG4848	Belongs to the UPF0354 family
CKF48_RS15990	COG1674	ftsk spoiiie
CKF48_RS16000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CKF48_RS16020	COG4980	gas vesicle protein
CKF48_RS16025	COG3118	belongs to the thioredoxin family
CKF48_RS16030	COG0849	cell division
CKF48_RS16035	COG1605	Chorismate mutase
CKF48_RS16035	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CKF48_RS16040	COG1609	Transcriptional regulator
CKF48_RS16045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CKF48_RS16060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CKF48_RS16060	COG0456	acetyltransferase
CKF48_RS16065	COG0583	DNA-binding transcription factor activity
CKF48_RS16070	COG2814	Major facilitator Superfamily
CKF48_RS16075	COG0583	DNA-binding transcription factor activity
CKF48_RS16080	COG0655	NAD(P)H dehydrogenase (quinone) activity
CKF48_RS16085	COG0662	Cupin 2, conserved barrel domain protein
CKF48_RS16105	COG0123	including yeast histone deacetylase and acetoin utilization protein
CKF48_RS16110	COG0517	IMP dehydrogenase activity
CKF48_RS16115	COG0454	-acetyltransferase
CKF48_RS16120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_RS16140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CKF48_RS16160	COG1562	ergosterol biosynthetic process
CKF48_RS16195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CKF48_RS16205	COG1064	alcohol dehydrogenase
CKF48_RS16210	COG0789	Transcriptional regulator
CKF48_RS16220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CKF48_RS16225	COG2203	Gaf domain
CKF48_RS16225	COG2199	diguanylate cyclase activity
CKF48_RS16235	COG1956	GAF domain-containing protein
CKF48_RS16240	COG1309	transcriptional regulator
CKF48_RS16245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CKF48_RS16250	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CKF48_RS16255	COG1114	Component of the transport system for branched-chain amino acids
CKF48_RS16260	COG1104	cysteine desulfurase activity
CKF48_RS16265	COG0301	tRNA thio-modification
CKF48_RS16275	COG0583	DNA-binding transcription factor activity
CKF48_RS16280	COG0010	Belongs to the arginase family
CKF48_RS16285	COG0786	glutamate:sodium symporter activity
CKF48_RS16290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_RS16295	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CKF48_RS16300	COG2962	Rard protein
CKF48_RS16305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CKF48_RS16315	COG1714	RDD family
CKF48_RS16325	COG3874	Sporulation protein YtfJ
CKF48_RS16330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CKF48_RS16335	COG0827	DNA restriction-modification system
CKF48_RS16340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CKF48_RS16350	COG0521	Mo-molybdopterin cofactor biosynthetic process
CKF48_RS16360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CKF48_RS16365	COG0137	argininosuccinate synthase activity
CKF48_RS16370	COG0165	Argininosuccinate lyase
CKF48_RS16375	COG0589	response to stress
CKF48_RS16385	COG4145	pantothenate transmembrane transporter activity
CKF48_RS16390	COG0471	metal ion transport
CKF48_RS16400	COG0006	proline dipeptidase activity
CKF48_RS16405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CKF48_RS16415	COG4109	DRTGG domain
CKF48_RS16425	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CKF48_RS16440	COG0587	DNA-directed DNA polymerase activity
CKF48_RS16445	COG0281	malic enzyme
CKF48_RS16450	COG1725	Transcriptional regulator
CKF48_RS16455	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CKF48_RS16460	COG0825	malonyl-CoA metabolic process
CKF48_RS16465	COG0205	6-phosphofructokinase activity
CKF48_RS16475	COG0471	metal ion transport
CKF48_RS16480	COG3030	protein affecting phage T7 exclusion by the F plasmid
CKF48_RS16485	COG0628	permease
CKF48_RS16490	COG2707	UPF0756 membrane protein
CKF48_RS16495	COG0372	Belongs to the citrate synthase family
CKF48_RS16500	COG0538	isocitrate dehydrogenase activity
CKF48_RS16505	COG0039	L-malate dehydrogenase activity
CKF48_RS16520	COG5002	protein histidine kinase activity
CKF48_RS16525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKF48_RS16525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKF48_RS16530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CKF48_RS16535	COG1971	Probably functions as a manganese efflux pump
CKF48_RS16540	COG0237	dephospho-CoA kinase activity
CKF48_RS16545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CKF48_RS16550	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CKF48_RS16555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CKF48_RS16565	COG1484	DNA-dependent DNA replication
CKF48_RS16575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CKF48_RS16580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CKF48_RS16590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CKF48_RS16595	COG3326	Membrane
CKF48_RS16600	COG0398	Pfam SNARE associated Golgi protein
CKF48_RS16610	COG0756	dUTP diphosphatase activity
CKF48_RS16615	COG1363	Peptidase, m42
CKF48_RS16625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CKF48_RS16630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CKF48_RS16635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CKF48_RS16635	COG0072	phenylalanine-tRNA ligase activity
CKF48_RS16645	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CKF48_RS16650	COG1286	toxin biosynthetic process
CKF48_RS16655	COG1796	DNA polymerase
CKF48_RS16655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CKF48_RS16665	COG3766	membrane
CKF48_RS16670	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS16675	COG1309	transcriptional regulator
CKF48_RS16680	COG1024	Enoyl-CoA hydratase
CKF48_RS16685	COG2086	electron transfer activity
CKF48_RS16690	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CKF48_RS16695	COG3118	belongs to the thioredoxin family
CKF48_RS16700	COG0322	excinuclease ABC activity
CKF48_RS16710	COG1719	4-vinyl reductase, 4VR
CKF48_RS16715	COG2009	succinate dehydrogenase
CKF48_RS16720	COG1053	succinate dehydrogenase
CKF48_RS16725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CKF48_RS16730	COG0737	Belongs to the 5'-nucleotidase family
CKF48_RS16735	COG0824	Thioesterase
CKF48_RS16740	COG2197	response regulator
CKF48_RS16745	COG1846	Transcriptional regulator
CKF48_RS16755	COG0514	ATP-dependent DNA helicase (RecQ)
CKF48_RS16760	COG5401	PFAM Sporulation and spore germination
CKF48_RS16770	COG0622	Phosphoesterase
CKF48_RS16780	COG0028	Belongs to the TPP enzyme family
CKF48_RS16785	COG0440	acetolactate synthase activity
CKF48_RS16795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKF48_RS16800	COG0473	3-isopropylmalate dehydrogenase activity
CKF48_RS16805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CKF48_RS16810	COG0066	3-isopropylmalate dehydratase activity
CKF48_RS16815	COG1477	protein flavinylation
CKF48_RS16815	COG0457	Tetratricopeptide repeat
CKF48_RS16820	COG0544	peptidyl-prolyl cis-trans isomerase activity
CKF48_RS16825	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CKF48_RS16830	COG1067	ATP-dependent peptidase activity
CKF48_RS16830	COG0470	DNA polymerase III
CKF48_RS16835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CKF48_RS16840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CKF48_RS16845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_RS16850	COG0765	amino acid transport
CKF48_RS16855	COG1126	abc transporter atp-binding protein
CKF48_RS16870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CKF48_RS16885	COG0113	porphobilinogen synthase activity
CKF48_RS16890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKF48_RS16895	COG1388	LysM domain
CKF48_RS16895	COG1388	LysM domain
CKF48_RS16905	COG0525	valine-tRNA ligase activity
CKF48_RS16910	COG0285	dihydrofolate synthase activity
CKF48_RS16935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKF48_RS16945	COG1459	type II secretion system
CKF48_RS16950	COG4968	Prepilin-type N-terminal cleavage methylation domain
CKF48_RS16955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CKF48_RS16980	COG0424	maF-like protein
CKF48_RS16985	COG2003	Belongs to the UPF0758 family
CKF48_RS16990	COG1077	Cell shape determining protein MreB Mrl
CKF48_RS16995	COG1792	Involved in formation and maintenance of cell shape
CKF48_RS17000	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CKF48_RS17005	COG0850	regulation of cytokinetic process
CKF48_RS17010	COG2894	cell division
CKF48_RS17015	COG0739	heme binding
CKF48_RS17020	COG1994	Peptidase M50
CKF48_RS17030	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CKF48_RS17035	COG2868	ribosomal protein
CKF48_RS17040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CKF48_RS17045	COG3290	protein histidine kinase activity
CKF48_RS17050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CKF48_RS17055	COG4492	Belongs to the UPF0735 family
CKF48_RS17060	COG0077	Prephenate dehydratase
CKF48_RS17065	COG1827	regulation of RNA biosynthetic process
CKF48_RS17070	COG1104	cysteine desulfurase activity
CKF48_RS17075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CKF48_RS17080	COG0157	Belongs to the NadC ModD family
CKF48_RS17085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CKF48_RS17090	COG1388	LysM domain
CKF48_RS17110	COG0582	viral genome integration into host DNA
CKF48_RS17125	COG2111	Na H antiporter
CKF48_RS17130	COG1006	Multisubunit Na H antiporter MnhC subunit
CKF48_RS17135	COG0651	ATP synthesis coupled electron transport
CKF48_RS17140	COG1863	multisubunit Na H antiporter MnhE subunit
CKF48_RS17145	COG2212	antiporter activity
CKF48_RS17150	COG1320	monovalent cation:proton antiporter activity
CKF48_RS17180	COG1862	Preprotein translocase
CKF48_RS17190	COG2323	membrane
CKF48_RS17195	COG2244	polysaccharide biosynthetic process
CKF48_RS17205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKF48_RS17205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CKF48_RS17210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CKF48_RS17215	COG5416	Lipopolysaccharide assembly protein A domain
CKF48_RS17220	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CKF48_RS17220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CKF48_RS17225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKF48_RS17230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CKF48_RS17235	COG1490	D-aminoacyl-tRNA deacylase activity
CKF48_RS17240	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_RS17240	COG4991	sh3 domain protein
CKF48_RS17240	COG3103	Sh3 type 3 domain protein
CKF48_RS17245	COG0124	histidyl-tRNA synthetase
CKF48_RS17250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CKF48_RS17270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CKF48_RS17285	COG1725	Transcriptional regulator
CKF48_RS17290	COG1131	(ABC) transporter
CKF48_RS17295	COG1131	(ABC) transporter
CKF48_RS17300	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CKF48_RS17310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CKF48_RS17315	COG2364	Membrane
CKF48_RS17320	COG1959	2 iron, 2 sulfur cluster binding
CKF48_RS17325	COG1104	cysteine desulfurase activity
CKF48_RS17330	COG0482	sulfurtransferase activity
CKF48_RS17340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CKF48_RS17360	COG0628	permease
CKF48_RS17370	COG4472	Bacterial protein of unknown function (DUF965)
CKF48_RS17380	COG3906	Belongs to the UPF0473 family
CKF48_RS17385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CKF48_RS17390	COG4122	O-methyltransferase activity
CKF48_RS17395	COG0572	uridine kinase
CKF48_RS17400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CKF48_RS17405	COG0768	penicillin binding
CKF48_RS17430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CKF48_RS17435	COG0626	cystathionine gamma-synthase activity
CKF48_RS17450	COG2329	Antibiotic biosynthesis monooxygenase
CKF48_RS17460	COG0688	phosphatidylethanolamine metabolic process
CKF48_RS17470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CKF48_RS17475	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CKF48_RS17485	COG1534	Rna-binding protein
CKF48_RS17490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CKF48_RS17495	COG1713	HD superfamily hydrolase involved in NAD metabolism
CKF48_RS17500	COG0799	negative regulation of ribosome biogenesis
CKF48_RS17505	COG2226	methyltransferase
CKF48_RS17510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_RS17515	COG1555	photosystem II stabilization
CKF48_RS17515	COG1596	polysaccharide export
CKF48_RS17520	COG2131	deaminase
CKF48_RS17525	COG2333	competence protein COMEC
CKF48_RS17525	COG0658	competence protein
CKF48_RS17535	COG1466	dna polymerase III delta subunit
CKF48_RS17540	COG0268	Binds directly to 16S ribosomal RNA
CKF48_RS17545	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CKF48_RS17555	COG0481	GTPase activity
CKF48_RS17560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKF48_RS17565	COG1420	regulation of RNA biosynthetic process
CKF48_RS17570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CKF48_RS17575	COG0443	Heat shock 70 kDa protein
CKF48_RS17585	COG2264	protein methyltransferase activity
CKF48_RS17590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CKF48_RS17595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CKF48_RS17605	COG3620	sequence-specific DNA binding
CKF48_RS17610	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CKF48_RS17615	COG1283	sodium-dependent phosphate transmembrane transporter activity
CKF48_RS17625	COG1610	YqeY-like protein
CKF48_RS17630	COG1030	water channel activity
CKF48_RS17635	COG4864	UPF0365 protein
CKF48_RS17655	COG1702	phosphate starvation-inducible protein PhoH
CKF48_RS17660	COG1480	7TM receptor with intracellular HD hydrolase
CKF48_RS17670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CKF48_RS17675	COG0295	cytidine deaminase activity
CKF48_RS17690	COG1381	Involved in DNA repair and RecF pathway recombination
CKF48_RS17695	COG0752	glycyl-tRNA synthetase alpha subunit
CKF48_RS17700	COG0751	glycine-tRNA ligase activity
CKF48_RS17705	COG0517	IMP dehydrogenase activity
CKF48_RS17710	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CKF48_RS17715	COG1671	Belongs to the UPF0178 family
CKF48_RS17720	COG0358	DNA primase activity
CKF48_RS17725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CKF48_RS17730	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS17735	COG2010	Cytochrome c
CKF48_RS17740	COG2384	SAM-dependent methyltransferase
CKF48_RS17745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CKF48_RS17760	COG0513	Belongs to the DEAD box helicase family
CKF48_RS17765	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CKF48_RS17775	COG1121	(ABC) transporter
CKF48_RS17780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_RS17785	COG0735	belongs to the Fur family
CKF48_RS17790	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CKF48_RS17795	COG4709	membrane
CKF48_RS17800	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CKF48_RS17810	COG5521	maltodextrose utilization protein MalA
CKF48_RS17815	COG1283	sodium-dependent phosphate transmembrane transporter activity
CKF48_RS17820	COG2839	Protein conserved in bacteria
CKF48_RS17825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKF48_RS17830	COG0477	Major facilitator Superfamily
CKF48_RS17835	COG0768	penicillin binding
CKF48_RS17840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CKF48_RS17845	COG0573	inorganic phosphate transmembrane transporter activity
CKF48_RS17850	COG0581	inorganic phosphate transmembrane transporter activity
CKF48_RS17855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKF48_RS17860	COG0704	Plays a role in the regulation of phosphate uptake
CKF48_RS17905	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CKF48_RS17920	COG0705	Rhomboid family
CKF48_RS17920	COG0457	Tetratricopeptide repeat
CKF48_RS17925	COG0697	spore germination
CKF48_RS17930	COG4483	Protein conserved in bacteria
CKF48_RS17935	COG1940	carbohydrate kinase activity
CKF48_RS17950	COG0011	TIGRFAM Protein of
CKF48_RS17960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS17980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CKF48_RS17985	COG1459	type II secretion system
CKF48_RS17990	COG4537	Required for transformation and DNA binding
CKF48_RS17995	COG4970	Tfp pilus assembly protein FimT
CKF48_RS18025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKF48_RS18030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CKF48_RS18040	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CKF48_RS18045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CKF48_RS18050	COG0095	Lipoate-protein ligase
CKF48_RS18060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_RS18065	COG1752	Esterase of the alpha-beta hydrolase superfamily
CKF48_RS18080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CKF48_RS18085	COG0006	proline dipeptidase activity
CKF48_RS18090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CKF48_RS18100	COG1785	Belongs to the alkaline phosphatase family
CKF48_RS18145	COG0511	ligase activity, forming carbon-carbon bonds
CKF48_RS18150	COG0439	Biotin carboxylase
CKF48_RS18155	COG1302	Protein conserved in bacteria
CKF48_RS18160	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CKF48_RS18165	COG1570	exodeoxyribonuclease VII activity
CKF48_RS18170	COG1722	exodeoxyribonuclease VII activity
CKF48_RS18180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CKF48_RS18185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CKF48_RS18190	COG1438	arginine binding
CKF48_RS18195	COG0497	DNA recombination
CKF48_RS18200	COG0750	zinc metalloprotease
CKF48_RS18205	COG0745	RESPONSE REGULATOR receiver
CKF48_RS18210	COG4974	Belongs to the 'phage' integrase family
CKF48_RS18240	COG0582	viral genome integration into host DNA
CKF48_RS18310	COG3829	transcription factor binding
CKF48_RS18310	COG3290	protein histidine kinase activity
CKF48_RS18315	COG0280	phosphate acetyltransferase
CKF48_RS18325	COG3426	butyrate kinase activity
CKF48_RS18330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CKF48_RS18335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CKF48_RS18340	COG0022	dehydrogenase e1 component
CKF48_RS18345	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKF48_RS18350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_RS18355	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_RS18355	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CKF48_RS18360	COG1703	isobutyryl-CoA mutase activity
CKF48_RS18370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CKF48_RS18375	COG0765	amino acid transport
CKF48_RS18380	COG1126	abc transporter atp-binding protein
CKF48_RS18385	COG4129	membrane
CKF48_RS18390	COG1376	ErfK ybiS ycfS ynhG family protein
CKF48_RS18395	COG0346	lactoylglutathione lyase activity
CKF48_RS18400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CKF48_RS18405	COG2195	Cleaves the N-terminal amino acid of tripeptides
CKF48_RS18415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CKF48_RS18420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CKF48_RS18425	COG1234	tRNA 3'-trailer cleavage
CKF48_RS18430	COG0733	neurotransmitter:sodium symporter activity
CKF48_RS18435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CKF48_RS18440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS18445	COG0300	oxidoreductase activity
CKF48_RS18450	COG1902	pentaerythritol trinitrate reductase activity
CKF48_RS18455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CKF48_RS18465	COG0583	DNA-binding transcription factor activity
CKF48_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS18505	COG1073	alpha beta
CKF48_RS18510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CKF48_RS18525	COG0667	Aldo Keto reductase
CKF48_RS18540	COG1379	DNA repair
CKF48_RS18545	COG0697	spore germination
CKF48_RS18555	COG1300	Membrane
CKF48_RS18560	COG0735	belongs to the Fur family
CKF48_RS18570	COG4974	Belongs to the 'phage' integrase family
CKF48_RS18590	COG1686	Belongs to the peptidase S11 family
CKF48_RS18625	COG0697	spore germination
CKF48_RS18640	COG1547	Domain of unknown function (DUF309)
CKF48_RS18650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CKF48_RS18655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CKF48_RS18670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CKF48_RS18675	COG1686	Belongs to the peptidase S11 family
CKF48_RS18680	COG2715	membrane protein required for spore maturation
CKF48_RS18685	COG0700	Nucleoside recognition
CKF48_RS18690	COG1187	pseudouridine synthase activity
CKF48_RS18700	COG1333	cytochrome c biogenesis protein
CKF48_RS18705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CKF48_RS18710	COG0745	RESPONSE REGULATOR receiver
CKF48_RS18715	COG5002	protein histidine kinase activity
CKF48_RS18720	COG1595	DNA-templated transcription, initiation
CKF48_RS18730	COG0739	heme binding
CKF48_RS18735	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CKF48_RS18740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CKF48_RS18745	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CKF48_RS18750	COG1141	Ferredoxin
CKF48_RS18755	COG4955	Helix-turn-helix domain
CKF48_RS18765	COG1266	CAAX protease self-immunity
CKF48_RS18770	COG0791	NLP P60 protein
CKF48_RS18770	COG1388	LysM domain
CKF48_RS18780	COG1408	metallophosphoesterase
CKF48_RS18785	COG4862	establishment of competence for transformation
CKF48_RS18790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CKF48_RS18795	COG0492	ferredoxin-NADP+ reductase activity
CKF48_RS18800	COG0252	asparaginase activity
CKF48_RS18805	COG2339	peptidase activity
CKF48_RS18810	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_RS18810	COG3773	Cell wall hydrolase
CKF48_RS18815	COG2959	enzyme of heme biosynthesis
CKF48_RS18830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CKF48_RS18835	COG0204	Acyl-transferase
CKF48_RS18840	COG0539	negative regulation of cytoplasmic translation
CKF48_RS18845	COG1304	FMN binding
CKF48_RS18870	COG1160	GTP binding
CKF48_RS18875	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CKF48_RS18890	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CKF48_RS18895	COG0776	regulation of translation
CKF48_RS18900	COG0302	gtp cyclohydrolase
CKF48_RS18910	COG0142	geranyltranstransferase activity
CKF48_RS18915	COG2226	methyltransferase
CKF48_RS18920	COG0142	geranyltranstransferase activity
CKF48_RS18925	COG0105	UTP biosynthetic process
CKF48_RS18930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CKF48_RS18940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CKF48_RS18945	COG4401	Chorismate mutase type I
CKF48_RS18950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CKF48_RS18955	COG0287	Prephenate dehydrogenase
CKF48_RS18960	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CKF48_RS18970	COG0457	Tetratricopeptide repeat
CKF48_RS18975	COG5582	Belongs to the UPF0302 family
CKF48_RS18990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CKF48_RS19000	COG4347	Protein of unknown function (DUF1405)
CKF48_RS19020	COG2738	Putative neutral zinc metallopeptidase
CKF48_RS19025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CKF48_RS19030	COG1694	Mazg nucleotide pyrophosphohydrolase
CKF48_RS19035	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CKF48_RS19040	COG1803	Methylglyoxal synthase
CKF48_RS19045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CKF48_RS19050	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS19055	COG0617	tRNA 3'-terminal CCA addition
CKF48_RS19065	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CKF48_RS19070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CKF48_RS19075	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CKF48_RS19080	COG2304	oxidoreductase activity
CKF48_RS19085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CKF48_RS19085	COG1199	ATP-dependent helicase activity
CKF48_RS19100	COG0436	Aminotransferase
CKF48_RS19105	COG0017	Asparaginyl-tRNA synthetase
CKF48_RS19110	COG3935	DnaD domain protein
CKF48_RS19115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CKF48_RS19125	COG4499	WXG100 protein secretion system (Wss), protein YukC
CKF48_RS19125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CKF48_RS19130	COG3331	DNA recombination
CKF48_RS19155	COG0601	transmembrane transport
CKF48_RS19160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CKF48_RS19165	COG0071	Belongs to the small heat shock protein (HSP20) family
CKF48_RS19170	COG1205	dead DEAH box helicase
CKF48_RS19170	COG1111	helicase
CKF48_RS19175	COG3359	exonuclease
CKF48_RS19190	COG4474	Belongs to the UPF0398 family
CKF48_RS19205	COG0116	Belongs to the methyltransferase superfamily
CKF48_RS19210	COG1199	ATP-dependent helicase activity
CKF48_RS19215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CKF48_RS19220	COG0697	spore germination
CKF48_RS19225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CKF48_RS19230	COG2233	PERMEase
CKF48_RS19240	COG0860	N-Acetylmuramoyl-L-alanine amidase
CKF48_RS19250	COG2427	Protein of unknown function (DUF1641)
CKF48_RS19255	COG3383	formate dehydrogenase (NAD+) activity
CKF48_RS19260	COG5609	conserved protein (DUF2294)
CKF48_RS19265	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CKF48_RS19270	COG2116	formate transmembrane transporter activity
CKF48_RS19275	COG3424	synthase
CKF48_RS19280	COG1755	Isoprenylcysteine carboxyl methyltransferase
CKF48_RS19285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CKF48_RS19300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CKF48_RS19310	COG1533	DNA photolyase activity
CKF48_RS19320	COG0697	spore germination
CKF48_RS19325	COG0328	RNA-DNA hybrid ribonuclease activity
CKF48_RS19330	COG0328	RNA-DNA hybrid ribonuclease activity
CKF48_RS19340	COG1278	Cold shock
CKF48_RS19350	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKF48_RS19360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_RS19360	COG1321	iron dependent repressor
CKF48_RS19365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_RS19370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CKF48_RS19375	COG1321	iron dependent repressor
CKF48_RS19390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CKF48_RS19405	COG0488	(ABC) transporter
CKF48_RS19410	COG1413	lyase activity
CKF48_RS19430	COG2136	Putative SAM-dependent methyltransferase
CKF48_RS19430	COG2521	methyltransferase
CKF48_RS19435	COG0436	Aminotransferase
CKF48_RS19445	COG0861	Integral membrane protein TerC family
CKF48_RS19475	COG3853	Toxic anion resistance protein (TelA)
CKF48_RS19480	COG2310	stress, protein
CKF48_RS19495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CKF48_RS19500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CKF48_RS19520	COG1307	EDD domain protein, DegV family
CKF48_RS19530	COG2755	lipolytic protein G-D-S-L family
CKF48_RS19545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKF48_RS19550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CKF48_RS19575	COG1619	proteins homologs of microcin C7 resistance protein MccF
CKF48_RS19580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKF48_RS19585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CKF48_RS19590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CKF48_RS19595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CKF48_RS19600	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS19610	COG3829	transcription factor binding
CKF48_RS19615	COG1509	lysine 2,3-aminomutase activity
CKF48_RS19625	COG4479	Belongs to the UPF0346 family
CKF48_RS19630	COG2188	Transcriptional regulator
CKF48_RS19650	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS19655	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS19660	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CKF48_RS19680	COG0584	glycerophosphoryl diester phosphodiesterase
CKF48_RS19690	COG0813	purine-nucleoside phosphorylase activity
CKF48_RS19695	COG1876	peptidase activity
CKF48_RS19705	COG3409	Peptidoglycan-binding domain 1 protein
CKF48_RS19705	COG0793	Belongs to the peptidase S41A family
CKF48_RS19710	COG2814	Major facilitator Superfamily
CKF48_RS19730	COG0523	cobalamin synthesis protein
CKF48_RS19755	COG0745	RESPONSE REGULATOR receiver
CKF48_RS19760	COG3850	Histidine kinase
CKF48_RS19760	COG5002	protein histidine kinase activity
CKF48_RS19765	COG2340	Cysteine-rich secretory protein family
CKF48_RS19775	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS19780	COG1231	oxidoreductase activity
CKF48_RS19790	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS19805	COG1228	amidohydrolase
CKF48_RS19820	COG2323	membrane
CKF48_RS19825	COG2318	DinB family
CKF48_RS19840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_RS19860	COG1609	Transcriptional regulator
CKF48_RS19865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CKF48_RS19880	COG1172	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS19885	COG1879	ABC-type sugar transport system periplasmic component
CKF48_RS19910	COG0307	riboflavin synthase, alpha
CKF48_RS19915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_RS19915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CKF48_RS19920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CKF48_RS19925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CKF48_RS19935	COG3285	dna ligase
CKF48_RS19935	COG1793	dna ligase
CKF48_RS19940	COG1793	dna ligase
CKF48_RS19950	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CKF48_RS19955	COG0671	phosphoesterase, PA-phosphatase related
CKF48_RS19960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CKF48_RS19965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CKF48_RS19970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CKF48_RS19975	COG1278	Cold shock
CKF48_RS19980	COG0513	Belongs to the DEAD box helicase family
CKF48_RS20010	COG1115	amino acid carrier protein
CKF48_RS20015	COG1959	2 iron, 2 sulfur cluster binding
CKF48_RS20035	COG2608	mercury ion transmembrane transporter activity
CKF48_RS20040	COG2217	Heavy metal translocating P-type atpase
CKF48_RS20045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_RS20050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CKF48_RS20060	COG5002	protein histidine kinase activity
CKF48_RS20060	COG3850	Histidine kinase
CKF48_RS20090	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS20095	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS20100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CKF48_RS20105	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS20110	COG0183	Belongs to the thiolase family
CKF48_RS20115	COG1024	Enoyl-CoA hydratase
CKF48_RS20125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CKF48_RS20140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CKF48_RS20140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CKF48_RS20140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CKF48_RS20145	COG2814	Major facilitator Superfamily
CKF48_RS20160	COG0512	Glutamine amidotransferase of anthranilate synthase
CKF48_RS20160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKF48_RS20165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CKF48_RS20195	COG0753	catalase activity
CKF48_RS20200	COG2135	peptidase activity
CKF48_RS20215	COG0789	Transcriptional regulator
CKF48_RS20220	COG2966	Psort location CytoplasmicMembrane, score
CKF48_RS20230	COG1472	Belongs to the glycosyl hydrolase 3 family
CKF48_RS20235	COG1132	(ABC) transporter
CKF48_RS20240	COG3153	acetyltransferase
CKF48_RS20240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CKF48_RS20255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CKF48_RS20260	COG0791	NLP P60 protein
CKF48_RS20260	COG3883	PFAM NLP P60 protein
CKF48_RS20265	COG2186	Transcriptional regulator
CKF48_RS20270	COG0277	FAD linked oxidase domain protein
CKF48_RS20275	COG0247	lactate metabolic process
CKF48_RS20280	COG0277	FAD linked oxidase domain protein
CKF48_RS20285	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CKF48_RS20290	COG0179	Fumarylacetoacetate (FAA) hydrolase
CKF48_RS20295	COG1414	Transcriptional regulator
CKF48_RS20300	COG1620	l-lactate permease
CKF48_RS20310	COG2226	methyltransferase
CKF48_RS20315	COG1846	Transcriptional regulator
CKF48_RS20325	COG0183	Belongs to the thiolase family
CKF48_RS20335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_RS20340	COG1183	phosphatidylcholine synthase activity
CKF48_RS20345	COG0322	excinuclease ABC activity
CKF48_RS20350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CKF48_RS20355	COG0573	inorganic phosphate transmembrane transporter activity
CKF48_RS20360	COG0581	inorganic phosphate transmembrane transporter activity
CKF48_RS20365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKF48_RS20370	COG0243	molybdopterin cofactor binding
CKF48_RS20390	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CKF48_RS20405	COG0861	Integral membrane protein TerC family
CKF48_RS20410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CKF48_RS20415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS20420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CKF48_RS20430	COG1408	metallophosphoesterase
CKF48_RS20445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CKF48_RS20450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CKF48_RS20450	COG0456	acetyltransferase
CKF48_RS20455	COG0406	alpha-ribazole phosphatase activity
CKF48_RS20460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CKF48_RS20460	COG2169	Transcriptional regulator
CKF48_RS20465	COG1473	amidohydrolase
CKF48_RS20470	COG1473	amidohydrolase
CKF48_RS20480	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CKF48_RS20490	COG1272	protein, Hemolysin III
CKF48_RS20495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CKF48_RS20505	COG0768	penicillin binding
CKF48_RS20510	COG0189	ligase activity
CKF48_RS20520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CKF48_RS20525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CKF48_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS20535	COG0326	Molecular chaperone. Has ATPase activity
CKF48_RS20545	COG0493	'glutamate synthase
CKF48_RS20550	COG0167	dihydroorotate dehydrogenase activity
CKF48_RS20575	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS20580	COG1169	isochorismate synthase
CKF48_RS20585	COG1021	2,3-dihydroxybenzoate-AMP ligase
CKF48_RS20590	COG3433	isochorismatase activity
CKF48_RS20590	COG1535	isochorismatase
CKF48_RS20595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CKF48_RS20600	COG3251	PFAM MbtH domain protein
CKF48_RS20615	COG3835	regulator
CKF48_RS20620	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS20625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CKF48_RS20635	COG0385	Bile acid
CKF48_RS20640	COG2814	Major facilitator Superfamily
CKF48_RS20665	COG1510	regulation of RNA biosynthetic process
CKF48_RS20670	COG0517	IMP dehydrogenase activity
CKF48_RS20670	COG1125	glycine betaine transport
CKF48_RS20675	COG1174	glycine betaine transport
CKF48_RS20685	COG1174	glycine betaine transport
CKF48_RS20695	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS20700	COG1272	protein, Hemolysin III
CKF48_RS20710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_RS20745	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CKF48_RS20750	COG2068	MobA-Related Protein
CKF48_RS20775	COG2814	Major facilitator Superfamily
CKF48_RS20795	COG1764	response to oxidative stress
CKF48_RS20800	COG0708	Exodeoxyribonuclease III
CKF48_RS20805	COG2323	membrane
CKF48_RS20815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CKF48_RS20825	COG1054	Belongs to the UPF0176 family
CKF48_RS20830	COG1051	belongs to the nudix hydrolase family
CKF48_RS20845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS20855	COG3227	Zinc metalloprotease (Elastase)
CKF48_RS20865	COG0681	Belongs to the peptidase S26 family
CKF48_RS20870	COG0628	permease
CKF48_RS20880	COG0737	Belongs to the 5'-nucleotidase family
CKF48_RS20895	COG3842	ATPase activity
CKF48_RS20900	COG1176	ABC-type spermidine putrescine transport system, permease component I
CKF48_RS20905	COG1177	transmembrane transport
CKF48_RS20930	COG4948	Mandelate Racemase Muconate Lactonizing
CKF48_RS20935	COG3949	Membrane
CKF48_RS20940	COG2861	carbohydrate metabolic process
CKF48_RS20950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CKF48_RS20960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CKF48_RS20965	COG1845	cytochrome c oxidase, subunit III
CKF48_RS20975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CKF48_RS20990	COG0567	Dehydrogenase, E1 component
CKF48_RS20995	COG0508	dehydrogenase complex catalyzes the overall conversion of
CKF48_RS21045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKF48_RS21050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CKF48_RS21060	COG1268	BioY protein
CKF48_RS21070	COG0494	nUDIX hydrolase
CKF48_RS21075	COG1335	isochorismatase
CKF48_RS21080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CKF48_RS21085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CKF48_RS21095	COG2340	Cysteine-rich secretory protein family
CKF48_RS21110	COG1917	Cupin 2, conserved barrel domain protein
CKF48_RS21110	COG4977	sequence-specific DNA binding
CKF48_RS21115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CKF48_RS21120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CKF48_RS21125	COG1228	amidohydrolase
CKF48_RS21130	COG3314	Sporulation integral membrane protein YlbJ
CKF48_RS21135	COG2404	hydrolase activity, acting on ester bonds
CKF48_RS21145	COG1686	Belongs to the peptidase S11 family
CKF48_RS21150	COG1683	Conserved Protein
CKF48_RS21155	COG0488	(ABC) transporter
CKF48_RS21165	COG0789	Transcriptional regulator
CKF48_RS21170	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS21195	COG1388	LysM domain
CKF48_RS21195	COG3584	3D domain protein
CKF48_RS21205	COG2310	stress, protein
CKF48_RS21210	COG2310	stress, protein
CKF48_RS21230	COG1418	mRNA catabolic process
CKF48_RS21235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CKF48_RS21265	COG1349	DNA-binding transcription factor activity
CKF48_RS21270	COG3842	ATPase activity
CKF48_RS21295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CKF48_RS21305	COG1404	Belongs to the peptidase S8 family
CKF48_RS21315	COG2027	D-alanyl-D-alanine carboxypeptidase
CKF48_RS21330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_RS21350	COG3239	Fatty acid desaturase
CKF48_RS21360	COG2197	response regulator
CKF48_RS21365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CKF48_RS21380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CKF48_RS21390	COG0351	phosphomethylpyrimidine kinase
CKF48_RS21390	COG0352	thiamine-phosphate diphosphorylase activity
CKF48_RS21395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CKF48_RS21400	COG0352	thiamine-phosphate diphosphorylase activity
CKF48_RS21415	COG1164	Oligoendopeptidase f
CKF48_RS21420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CKF48_RS21425	COG0656	L-ascorbic acid biosynthetic process
CKF48_RS21445	COG0346	lactoylglutathione lyase activity
CKF48_RS21455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CKF48_RS21460	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CKF48_RS21475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CKF48_RS21480	COG1119	ATPase activity
CKF48_RS21485	COG1132	(ABC) transporter
CKF48_RS21490	COG1132	(ABC) transporter
CKF48_RS21505	COG1733	regulation of RNA biosynthetic process
CKF48_RS21530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CKF48_RS21535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CKF48_RS21540	COG0523	cobalamin synthesis protein
CKF48_RS21545	COG1253	flavin adenine dinucleotide binding
CKF48_RS21550	COG1253	flavin adenine dinucleotide binding
CKF48_RS21570	COG2318	DinB family
CKF48_RS21585	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CKF48_RS21590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CKF48_RS21600	COG0803	Belongs to the bacterial solute-binding protein 9 family
CKF48_RS21605	COG3443	Belongs to the bacterial solute-binding protein 9 family
CKF48_RS21610	COG2814	Major facilitator Superfamily
CKF48_RS21625	COG2197	response regulator
CKF48_RS21635	COG2072	flavoprotein involved in K transport
CKF48_RS21640	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS21650	COG2226	methyltransferase
CKF48_RS21660	COG0745	RESPONSE REGULATOR receiver
CKF48_RS21665	COG2205	protein histidine kinase activity
CKF48_RS21670	COG0577	efflux transmembrane transporter activity
CKF48_RS21670	COG1136	(ABC) transporter
CKF48_RS21705	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CKF48_RS21720	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CKF48_RS21725	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CKF48_RS21730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CKF48_RS21735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CKF48_RS21740	COG4172	Belongs to the ABC transporter superfamily
CKF48_RS21745	COG4721	ABC-type cobalt transport system, permease component
CKF48_RS21770	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS21780	COG1012	belongs to the aldehyde dehydrogenase family
CKF48_RS21790	COG5609	conserved protein (DUF2294)
CKF48_RS21805	COG2897	thiosulfate sulfurtransferase activity
CKF48_RS21810	COG2186	Transcriptional regulator
CKF48_RS21815	COG0129	dihydroxy-acid dehydratase activity
CKF48_RS21840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CKF48_RS21875	COG1024	Enoyl-CoA hydratase
CKF48_RS21890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CKF48_RS21915	COG3829	transcription factor binding
CKF48_RS21915	COG3290	protein histidine kinase activity
CKF48_RS21920	COG0431	NADPH-dependent FMN reductase
CKF48_RS21925	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKF48_RS21930	COG0175	sulfate reduction
CKF48_RS21940	COG0529	Catalyzes the synthesis of activated sulfate
CKF48_RS21945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CKF48_RS21970	COG0730	response to heat
CKF48_RS21980	COG0583	DNA-binding transcription factor activity
CKF48_RS21985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CKF48_RS21995	COG0446	pyridine nucleotide-disulphide oxidoreductase
CKF48_RS22000	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CKF48_RS22045	COG0145	ligase activity
CKF48_RS22080	COG0657	acetylesterase activity
CKF48_RS22085	COG2072	flavoprotein involved in K transport
CKF48_RS22100	COG0187	DNA topoisomerase II activity
CKF48_RS22105	COG1832	CoA-binding protein
CKF48_RS22110	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CKF48_RS22115	COG4191	Histidine kinase
CKF48_RS22120	COG1114	Component of the transport system for branched-chain amino acids
CKF48_RS22125	COG1114	Component of the transport system for branched-chain amino acids
CKF48_RS22130	COG1802	Transcriptional regulator
CKF48_RS22145	COG0824	Thioesterase
CKF48_RS22150	COG0464	growth
CKF48_RS22165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CKF48_RS22175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CKF48_RS22195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CKF48_RS22200	COG0156	8-amino-7-oxononanoate synthase activity
CKF48_RS22210	COG0735	belongs to the Fur family
CKF48_RS22215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CKF48_RS22225	COG0488	(ABC) transporter
CKF48_RS22230	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS22240	COG3973	AAA domain
CKF48_RS22245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CKF48_RS22255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CKF48_RS22260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CKF48_RS22265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_RS22270	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22275	COG1024	Enoyl-CoA hydratase
CKF48_RS22280	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CKF48_RS22345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CKF48_RS22350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CKF48_RS22355	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22365	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CKF48_RS22380	COG1802	Transcriptional regulator
CKF48_RS22390	COG0473	3-isopropylmalate dehydrogenase activity
CKF48_RS22395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CKF48_RS22400	COG0390	transport system, permease component
CKF48_RS22415	COG0753	catalase activity
CKF48_RS22420	COG1760	l-serine dehydratase
CKF48_RS22425	COG1760	l-serine dehydratase
CKF48_RS22440	COG1368	sulfuric ester hydrolase activity
CKF48_RS22465	COG1363	Peptidase, m42
CKF48_RS22470	COG1216	Glycosyl transferase, family 2
CKF48_RS22480	COG1216	Glycosyl transferase, family 2
CKF48_RS22505	COG0438	transferase activity, transferring glycosyl groups
CKF48_RS22515	COG1086	Polysaccharide biosynthesis protein
CKF48_RS22530	COG0613	PHP domain protein
CKF48_RS22535	COG1876	peptidase activity
CKF48_RS22545	COG0456	acetyltransferase
CKF48_RS22565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CKF48_RS22570	COG1116	anion transmembrane transporter activity
CKF48_RS22575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CKF48_RS22580	COG0604	alcohol dehydrogenase
CKF48_RS22585	COG4326	sporulation control protein
CKF48_RS22595	COG1024	Enoyl-CoA hydratase
CKF48_RS22605	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22610	COG1388	LysM domain
CKF48_RS22610	COG0791	NLP P60 protein
CKF48_RS22615	COG5522	Integral membrane protein (intg_mem_TP0381)
CKF48_RS22620	COG2130	NADP-dependent
CKF48_RS22630	COG0410	ABC transporter
CKF48_RS22645	COG0559	Belongs to the binding-protein-dependent transport system permease family
CKF48_RS22650	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS22655	COG1024	Enoyl-CoA hydratase
CKF48_RS22680	COG0183	Belongs to the thiolase family
CKF48_RS22685	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS22705	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS22710	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CKF48_RS22735	COG0454	-acetyltransferase
CKF48_RS22750	COG0420	3'-5' exonuclease activity
CKF48_RS22780	COG0281	malic enzyme
CKF48_RS22805	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CKF48_RS22815	COG0028	Belongs to the TPP enzyme family
CKF48_RS22820	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS22840	COG1414	Transcriptional regulator
CKF48_RS22845	COG2267	carboxylic ester hydrolase activity
CKF48_RS22850	COG4876	unkown
CKF48_RS22855	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS22860	COG0318	PFAM AMP-dependent synthetase and ligase
CKF48_RS22865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CKF48_RS22870	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22875	COG2204	response regulator
CKF48_RS22890	COG1960	acyl-CoA dehydrogenase activity
CKF48_RS22980	COG0791	NLP P60 protein
CKF48_RS22980	COG0741	lytic transglycosylase activity
CKF48_RS23050	COG2002	toxin-antitoxin pair type II binding
CKF48_RS23060	COG2003	Belongs to the UPF0758 family
CKF48_RS23115	COG1309	transcriptional regulator
CKF48_RS23140	COG1595	DNA-templated transcription, initiation
CKF48_RS23150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CKF48_RS23180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CKF48_RS23205	COG1136	(ABC) transporter
CKF48_RS23230	COG0500	methyltransferase
CKF48_RS23230	COG3615	Tellurite resistance protein tehB
CKF48_RS23240	COG2819	hydrolase of the alpha beta superfamily
CKF48_RS23265	COG1132	(ABC) transporter
CKF48_RS23315	COG2003	Belongs to the UPF0758 family
CKF48_RS23335	COG0653	protein targeting
CKF48_RS23380	COG0406	alpha-ribazole phosphatase activity
CKF48_RS23400	COG1028	Short-chain dehydrogenase reductase Sdr
CKF48_RS23405	COG1733	regulation of RNA biosynthetic process
CKF48_RS23410	COG1472	Belongs to the glycosyl hydrolase 3 family
CKF48_RS23420	COG2267	carboxylic ester hydrolase activity
CKF48_RS23425	COG1846	Transcriptional regulator
CKF48_RS23430	COG3631	Ketosteroid isomerase-related protein
CKF48_RS23445	COG1733	regulation of RNA biosynthetic process
CKF48_RS23485	COG2002	toxin-antitoxin pair type II binding
CKF48_RS23510	COG1595	DNA-templated transcription, initiation
CKF48_RS23535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CKF48_RS23545	COG0697	spore germination
CKF48_RS23575	COG2427	Protein of unknown function (DUF1641)
CKF48_RS23580	COG3383	formate dehydrogenase (NAD+) activity