locus-tag	class	description
BkAM31D_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BkAM31D_RS00010	COG0592	DNA-directed DNA polymerase activity
BkAM31D_RS00015	COG2501	S4 domain
BkAM31D_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BkAM31D_RS00030	COG0187	DNA topoisomerase II activity
BkAM31D_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BkAM31D_RS00065	COG0516	GMP reductase activity
BkAM31D_RS00065	COG0517	IMP dehydrogenase activity
BkAM31D_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BkAM31D_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BkAM31D_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BkAM31D_RS00090	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_RS00095	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_RS00100	COG0601	transmembrane transport
BkAM31D_RS00105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_RS00110	COG0747	negative chemotaxis
BkAM31D_RS00120	COG0590	tRNA wobble adenosine to inosine editing
BkAM31D_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BkAM31D_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BkAM31D_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BkAM31D_RS00180	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS00185	COG1982	Orn Lys Arg decarboxylase major
BkAM31D_RS00190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BkAM31D_RS00195	COG3870	Protein conserved in bacteria
BkAM31D_RS00200	COG0470	DNA polymerase III
BkAM31D_RS00205	COG1774	PSP1 C-terminal conserved region
BkAM31D_RS00210	COG4467	Involved in initiation control of chromosome replication
BkAM31D_RS00215	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BkAM31D_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BkAM31D_RS00225	COG2002	toxin-antitoxin pair type II binding
BkAM31D_RS00240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BkAM31D_RS00240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BkAM31D_RS00245	COG0084	hydrolase, TatD family'
BkAM31D_RS00250	COG3583	domain protein
BkAM31D_RS00250	COG3584	3D domain protein
BkAM31D_RS00260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BkAM31D_RS00270	COG4466	Protein conserved in bacteria
BkAM31D_RS00280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BkAM31D_RS00285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BkAM31D_RS00290	COG0251	oxidation-reduction process
BkAM31D_RS00295	COG2088	sporulation resulting in formation of a cellular spore
BkAM31D_RS00300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BkAM31D_RS00305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BkAM31D_RS00310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BkAM31D_RS00325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BkAM31D_RS00330	COG2002	toxin-antitoxin pair type II binding
BkAM31D_RS00335	COG2244	polysaccharide biosynthetic process
BkAM31D_RS00340	COG3956	TIGRFAM MazG family protein
BkAM31D_RS00345	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BkAM31D_RS00365	COG1098	S1 RNA binding domain
BkAM31D_RS00375	COG2208	phosphoserine phosphatase activity
BkAM31D_RS00380	COG2304	oxidoreductase activity
BkAM31D_RS00400	COG0037	tRNA processing
BkAM31D_RS00405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BkAM31D_RS00410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BkAM31D_RS00420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BkAM31D_RS00425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BkAM31D_RS00430	COG2323	membrane
BkAM31D_RS00435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BkAM31D_RS00440	COG0512	Glutamine amidotransferase of anthranilate synthase
BkAM31D_RS00445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_RS00450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BkAM31D_RS00455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BkAM31D_RS00460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BkAM31D_RS00465	COG1396	sequence-specific DNA binding
BkAM31D_RS00470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BkAM31D_RS00475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BkAM31D_RS00495	COG2801	Transposase and inactivated derivatives
BkAM31D_RS00520	COG3880	PFAM UvrB UvrC protein
BkAM31D_RS00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BkAM31D_RS00530	COG0542	response to heat
BkAM31D_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BkAM31D_RS00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BkAM31D_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
BkAM31D_RS00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BkAM31D_RS00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BkAM31D_RS00565	COG1045	serine acetyltransferase
BkAM31D_RS00570	COG0215	cysteine-tRNA ligase activity
BkAM31D_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BkAM31D_RS00585	COG3688	RNA-binding protein containing a PIN domain
BkAM31D_RS00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BkAM31D_RS00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BkAM31D_RS00605	COG0250	Participates in transcription elongation, termination and antitermination
BkAM31D_RS00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BkAM31D_RS00615	COG0081	regulation of translation
BkAM31D_RS00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BkAM31D_RS00625	COG0222	ribosome binding
BkAM31D_RS00630	COG2813	Specifically methylates the guanine in position
BkAM31D_RS00635	COG0085	RNA polymerase activity
BkAM31D_RS00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BkAM31D_RS00645	COG1358	cellular component organization or biogenesis
BkAM31D_RS00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BkAM31D_RS00655	COG0049	tRNA binding
BkAM31D_RS00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BkAM31D_RS00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BkAM31D_RS00680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BkAM31D_RS00685	COG0088	Forms part of the polypeptide exit tunnel
BkAM31D_RS00690	COG0089	rRNA binding
BkAM31D_RS00695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BkAM31D_RS00700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BkAM31D_RS00705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BkAM31D_RS00710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BkAM31D_RS00715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BkAM31D_RS00720	COG0255	Belongs to the universal ribosomal protein uL29 family
BkAM31D_RS00725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BkAM31D_RS00730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BkAM31D_RS00735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BkAM31D_RS00740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BkAM31D_RS00745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BkAM31D_RS00750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BkAM31D_RS00755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BkAM31D_RS00760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BkAM31D_RS00765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BkAM31D_RS00770	COG1841	ribosomal large subunit assembly
BkAM31D_RS00775	COG0200	Binds to the 23S rRNA
BkAM31D_RS00785	COG0563	adenylate kinase activity
BkAM31D_RS00790	COG0024	Methionine aminopeptidase
BkAM31D_RS00800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BkAM31D_RS00805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BkAM31D_RS00810	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BkAM31D_RS00815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BkAM31D_RS00820	COG0202	RNA polymerase activity
BkAM31D_RS00825	COG0203	ribosomal protein L17
BkAM31D_RS00835	COG1122	ATPase activity
BkAM31D_RS00845	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BkAM31D_RS00850	COG0101	tRNA pseudouridine synthase activity
BkAM31D_RS00855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BkAM31D_RS00860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BkAM31D_RS00885	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_RS00890	COG0489	protein tyrosine kinase activity
BkAM31D_RS00900	COG2194	sulfuric ester hydrolase activity
BkAM31D_RS00905	COG0726	polysaccharide deacetylase
BkAM31D_RS00985	COG1595	DNA-templated transcription, initiation
BkAM31D_RS00990	COG5662	AntiSigma factor
BkAM31D_RS00995	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BkAM31D_RS01000	COG4856	YbbR-like protein
BkAM31D_RS01005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BkAM31D_RS01010	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BkAM31D_RS01020	COG1309	transcriptional regulator
BkAM31D_RS01025	COG0655	NAD(P)H dehydrogenase (quinone) activity
BkAM31D_RS01045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_RS01050	COG2223	nitrite transmembrane transporter activity
BkAM31D_RS01055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_RS01055	COG1263	PTS System
BkAM31D_RS01055	COG2190	(PTS) system
BkAM31D_RS01065	COG0596	Alpha beta hydrolase
BkAM31D_RS01070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_RS01075	COG0243	molybdopterin cofactor binding
BkAM31D_RS01085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BkAM31D_RS01085	COG1587	Uroporphyrinogen-III synthase
BkAM31D_RS01090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_RS01095	COG2146	nitrite reductase [NAD(P)H] activity
BkAM31D_RS01120	COG1587	Uroporphyrinogen-III synthase
BkAM31D_RS01125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BkAM31D_RS01130	COG1984	allophanate hydrolase subunit 2
BkAM31D_RS01135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BkAM31D_RS01145	COG2885	chlorophyll binding
BkAM31D_RS01160	COG1733	regulation of RNA biosynthetic process
BkAM31D_RS01165	COG0589	response to stress
BkAM31D_RS01175	COG2239	Acts as a magnesium transporter
BkAM31D_RS01205	COG0803	Belongs to the bacterial solute-binding protein 9 family
BkAM31D_RS01210	COG0705	Rhomboid family
BkAM31D_RS01215	COG0736	holo-[acyl-carrier-protein] synthase activity
BkAM31D_RS01220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BkAM31D_RS01225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BkAM31D_RS01230	COG0864	Transcriptional regulator
BkAM31D_RS01235	COG2337	Toxic component of a toxin-antitoxin (TA) module
BkAM31D_RS01240	COG1366	Belongs to the anti-sigma-factor antagonist family
BkAM31D_RS01245	COG1366	Belongs to the anti-sigma-factor antagonist family
BkAM31D_RS01250	COG2172	sigma factor antagonist activity
BkAM31D_RS01255	COG2208	phosphoserine phosphatase activity
BkAM31D_RS01265	COG2172	sigma factor antagonist activity
BkAM31D_RS01280	COG2183	response to ionizing radiation
BkAM31D_RS01290	COG3091	SprT-like family
BkAM31D_RS01375	COG0586	Pfam SNARE associated Golgi protein
BkAM31D_RS01380	COG2239	Acts as a magnesium transporter
BkAM31D_RS01385	COG0626	cystathionine gamma-synthase activity
BkAM31D_RS01400	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BkAM31D_RS01405	COG0802	atpase or kinase
BkAM31D_RS01410	COG1214	PFAM Peptidase M22, glycoprotease
BkAM31D_RS01415	COG0456	acetyltransferase
BkAM31D_RS01420	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BkAM31D_RS01440	COG0488	(ABC) transporter
BkAM31D_RS01445	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BkAM31D_RS01450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BkAM31D_RS01455	COG0805	protein transport
BkAM31D_RS01465	COG2814	Major facilitator Superfamily
BkAM31D_RS01475	COG1266	CAAX protease self-immunity
BkAM31D_RS01485	COG0459	protein refolding
BkAM31D_RS01490	COG1609	Transcriptional regulator
BkAM31D_RS01495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS01500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS01500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS01505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS01505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS01510	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BkAM31D_RS01520	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS01525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BkAM31D_RS01530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_RS01545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BkAM31D_RS01570	COG0601	transmembrane transport
BkAM31D_RS01580	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_RS01585	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_RS01590	COG0534	Mate efflux family protein
BkAM31D_RS01600	COG3119	arylsulfatase activity
BkAM31D_RS01605	COG1181	Belongs to the D-alanine--D-alanine ligase family
BkAM31D_RS01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BkAM31D_RS01620	COG2972	Histidine kinase
BkAM31D_RS01625	COG4753	response regulator
BkAM31D_RS01625	COG2207	Transcriptional regulator
BkAM31D_RS01640	COG1368	sulfuric ester hydrolase activity
BkAM31D_RS01650	COG0189	ligase activity
BkAM31D_RS01660	COG3290	protein histidine kinase activity
BkAM31D_RS01665	COG4565	transcriptional regulatory protein
BkAM31D_RS01670	COG2851	Citrate transporter
BkAM31D_RS01675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BkAM31D_RS01690	COG0714	Associated with various cellular activities
BkAM31D_RS01695	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BkAM31D_RS01700	COG1305	Transglutaminase-like
BkAM31D_RS01705	COG0519	Catalyzes the synthesis of GMP from XMP
BkAM31D_RS01705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BkAM31D_RS01710	COG2252	PERMEase
BkAM31D_RS01740	COG3424	synthase
BkAM31D_RS01745	COG1755	Isoprenylcysteine carboxyl methyltransferase
BkAM31D_RS01755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BkAM31D_RS01760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BkAM31D_RS01765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BkAM31D_RS01770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BkAM31D_RS01775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BkAM31D_RS01780	COG0047	phosphoribosylformylglycinamidine synthase activity
BkAM31D_RS01785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BkAM31D_RS01790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BkAM31D_RS01795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BkAM31D_RS01800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BkAM31D_RS01805	COG0138	bifunctional purine biosynthesis protein purh
BkAM31D_RS01810	COG0151	Belongs to the GarS family
BkAM31D_RS01820	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BkAM31D_RS01825	COG1470	cell adhesion involved in biofilm formation
BkAM31D_RS01830	COG4496	protein, YerC YecD
BkAM31D_RS01835	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BkAM31D_RS01840	COG2508	Transcriptional regulator
BkAM31D_RS01840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BkAM31D_RS01860	COG0393	Putative heavy-metal-binding
BkAM31D_RS01865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BkAM31D_RS01870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BkAM31D_RS01880	COG0210	DNA helicase
BkAM31D_RS01885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BkAM31D_RS01890	COG4851	CamS sex pheromone cAM373 precursor
BkAM31D_RS01895	COG1744	ABC transporter substrate-binding protein PnrA-like
BkAM31D_RS01900	COG3845	ABC transporter
BkAM31D_RS01905	COG4603	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS01920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BkAM31D_RS01925	COG0154	amidase activity
BkAM31D_RS01930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BkAM31D_RS01935	COG1597	lipid kinase activity
BkAM31D_RS01940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BkAM31D_RS01945	COG0582	viral genome integration into host DNA
BkAM31D_RS01960	COG3620	sequence-specific DNA binding
BkAM31D_RS02020	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BkAM31D_RS02045	COG3561	AntA/AntB antirepressor
BkAM31D_RS02095	COG0629	single-stranded DNA binding
BkAM31D_RS02145	COG5484	DNA packaging
BkAM31D_RS02145	COG3728	DNA packaging
BkAM31D_RS02280	COG3655	Transcriptional regulator
BkAM31D_RS02285	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS02345	COG1063	alcohol dehydrogenase
BkAM31D_RS02355	COG1609	Transcriptional regulator
BkAM31D_RS02360	COG0366	Alpha amylase catalytic
BkAM31D_RS02370	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS02375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_RS02385	COG0506	proline dehydrogenase activity
BkAM31D_RS02395	COG1054	Belongs to the UPF0176 family
BkAM31D_RS02400	COG1937	Protein conserved in bacteria
BkAM31D_RS02405	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS02420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS02420	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS02425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS02425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS02430	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS02435	COG0730	response to heat
BkAM31D_RS02440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BkAM31D_RS02445	COG3273	potassium ion transport
BkAM31D_RS02445	COG0471	metal ion transport
BkAM31D_RS02450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_RS02475	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BkAM31D_RS02485	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BkAM31D_RS02500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BkAM31D_RS02505	COG0156	8-amino-7-oxononanoate synthase activity
BkAM31D_RS02510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BkAM31D_RS02515	COG2124	cytochrome p450
BkAM31D_RS02525	COG3239	Fatty acid desaturase
BkAM31D_RS02530	COG4585	Histidine kinase
BkAM31D_RS02535	COG2197	response regulator
BkAM31D_RS02540	COG0028	Belongs to the TPP enzyme family
BkAM31D_RS02545	COG0583	DNA-binding transcription factor activity
BkAM31D_RS02550	COG4948	Mandelate Racemase Muconate Lactonizing
BkAM31D_RS02555	COG3181	Tripartite tricarboxylate transporter family receptor
BkAM31D_RS02570	COG4565	transcriptional regulatory protein
BkAM31D_RS02575	COG3290	protein histidine kinase activity
BkAM31D_RS02585	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS02600	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_RS02610	COG0659	secondary active sulfate transmembrane transporter activity
BkAM31D_RS02615	COG3835	regulator
BkAM31D_RS02625	COG3135	benzoate transporter
BkAM31D_RS02630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS02665	COG1141	Ferredoxin
BkAM31D_RS02670	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_RS02675	COG1024	Enoyl-CoA hydratase
BkAM31D_RS02700	COG1024	Enoyl-CoA hydratase
BkAM31D_RS02710	COG1024	Enoyl-CoA hydratase
BkAM31D_RS02715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS02740	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS02745	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS02755	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS02760	COG1024	Enoyl-CoA hydratase
BkAM31D_RS02770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_RS02785	COG2814	Major facilitator Superfamily
BkAM31D_RS02800	COG0681	Belongs to the peptidase S26 family
BkAM31D_RS02810	COG3706	GGDEF domain
BkAM31D_RS02815	COG1271	oxidase subunit
BkAM31D_RS02820	COG1294	oxidase, subunit
BkAM31D_RS02825	COG4988	ABC transporter
BkAM31D_RS02830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BkAM31D_RS02840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BkAM31D_RS02845	COG0840	transmembrane signaling receptor activity
BkAM31D_RS02860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BkAM31D_RS02865	COG2080	2 iron, 2 sulfur cluster binding
BkAM31D_RS02870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BkAM31D_RS02880	COG2508	Transcriptional regulator
BkAM31D_RS02885	COG3195	allantoin biosynthetic process
BkAM31D_RS02885	COG3648	Uricase
BkAM31D_RS02895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BkAM31D_RS02905	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BkAM31D_RS02920	COG1129	ABC transporter
BkAM31D_RS02925	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS02930	COG1132	(ABC) transporter
BkAM31D_RS02935	COG1132	(ABC) transporter
BkAM31D_RS02945	COG2059	Chromate
BkAM31D_RS02950	COG2059	Chromate
BkAM31D_RS02965	COG2244	polysaccharide biosynthetic process
BkAM31D_RS02970	COG1263	PTS System
BkAM31D_RS02970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_RS02975	COG0366	Alpha amylase catalytic
BkAM31D_RS02985	COG2188	Transcriptional regulator
BkAM31D_RS02990	COG0386	Belongs to the glutathione peroxidase family
BkAM31D_RS02995	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BkAM31D_RS03000	COG0488	(ABC) transporter
BkAM31D_RS03005	COG1349	DNA-binding transcription factor activity
BkAM31D_RS03010	COG1105	Belongs to the carbohydrate kinase PfkB family
BkAM31D_RS03015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BkAM31D_RS03015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BkAM31D_RS03015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BkAM31D_RS03035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BkAM31D_RS03040	COG1077	Cell shape determining protein MreB Mrl
BkAM31D_RS03045	COG1263	PTS System
BkAM31D_RS03045	COG2190	(PTS) system
BkAM31D_RS03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_RS03050	COG3711	transcriptional antiterminator
BkAM31D_RS03075	COG3341	Caulimovirus viroplasmin
BkAM31D_RS03075	COG0328	RNA-DNA hybrid ribonuclease activity
BkAM31D_RS03085	COG1522	sequence-specific DNA binding
BkAM31D_RS03095	COG0217	transcriptional regulatory protein
BkAM31D_RS03100	COG1294	oxidase, subunit
BkAM31D_RS03105	COG1271	oxidase subunit
BkAM31D_RS03115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS03135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_RS03140	COG2364	Membrane
BkAM31D_RS03155	COG0535	radical SAM domain protein
BkAM31D_RS03165	COG0406	alpha-ribazole phosphatase activity
BkAM31D_RS03185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BkAM31D_RS03200	COG4989	oxidoreductase activity
BkAM31D_RS03210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_RS03220	COG1917	Cupin 2, conserved barrel domain protein
BkAM31D_RS03225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_RS03230	COG0456	acetyltransferase
BkAM31D_RS03245	COG1090	epimerase
BkAM31D_RS03250	COG2137	regulation of response to DNA damage stimulus
BkAM31D_RS03255	COG1620	l-lactate permease
BkAM31D_RS03280	COG1988	membrane-bound metal-dependent
BkAM31D_RS03290	COG1194	a g-specific adenine glycosylase
BkAM31D_RS03295	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS03305	COG0604	alcohol dehydrogenase
BkAM31D_RS03305	COG3321	synthase
BkAM31D_RS03320	COG3557	Belongs to the UPF0374 family
BkAM31D_RS03325	COG1132	(ABC) transporter
BkAM31D_RS03330	COG4129	membrane
BkAM31D_RS03335	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BkAM31D_RS03345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BkAM31D_RS03350	COG3870	Protein conserved in bacteria
BkAM31D_RS03355	COG0735	belongs to the Fur family
BkAM31D_RS03470	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS03495	COG4695	Portal protein
BkAM31D_RS03555	COG2433	Pfam Transposase IS66
BkAM31D_RS03570	COG2801	Transposase and inactivated derivatives
BkAM31D_RS03580	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_RS03595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BkAM31D_RS03600	COG2188	Transcriptional regulator
BkAM31D_RS03605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BkAM31D_RS03630	COG0295	cytidine deaminase activity
BkAM31D_RS03635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BkAM31D_RS03645	COG3764	Sortase (surface protein transpeptidase)
BkAM31D_RS03650	COG0746	molybdenum cofactor guanylyltransferase activity
BkAM31D_RS03655	COG0521	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_RS03660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BkAM31D_RS03665	COG0303	'Molybdopterin
BkAM31D_RS03670	COG1763	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_RS03675	COG0314	molybdopterin synthase activity
BkAM31D_RS03680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BkAM31D_RS03690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BkAM31D_RS03695	COG2223	nitrite transmembrane transporter activity
BkAM31D_RS03700	COG5609	conserved protein (DUF2294)
BkAM31D_RS03710	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BkAM31D_RS03715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BkAM31D_RS03720	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BkAM31D_RS03745	COG0783	Belongs to the Dps family
BkAM31D_RS03750	COG3382	B3 4 domain protein
BkAM31D_RS03755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BkAM31D_RS03760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BkAM31D_RS03770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BkAM31D_RS03785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_RS03790	COG2766	serine protein kinase
BkAM31D_RS03800	COG2718	Belongs to the UPF0229 family
BkAM31D_RS03810	COG5002	protein histidine kinase activity
BkAM31D_RS03815	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS03820	COG0506	proline dehydrogenase activity
BkAM31D_RS03830	COG3314	Sporulation integral membrane protein YlbJ
BkAM31D_RS03835	COG1846	Transcriptional regulator
BkAM31D_RS03840	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_RS03845	COG4605	iron ion homeostasis
BkAM31D_RS03850	COG4604	ABC transporter, ATP-binding protein
BkAM31D_RS03855	COG4607	ABC-type enterochelin transport system periplasmic component
BkAM31D_RS03865	COG0436	Aminotransferase
BkAM31D_RS03870	COG3546	catalase activity
BkAM31D_RS03875	COG0584	glycerophosphoryl diester phosphodiesterase
BkAM31D_RS03880	COG0058	SHG alpha-glucan phosphorylase activity
BkAM31D_RS03885	COG0297	glycogen (starch) synthase activity
BkAM31D_RS03890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BkAM31D_RS03895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BkAM31D_RS03905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BkAM31D_RS03905	COG3153	acetyltransferase
BkAM31D_RS03915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BkAM31D_RS03920	COG2719	SpoVR family
BkAM31D_RS03925	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS03930	COG3850	Histidine kinase
BkAM31D_RS03930	COG5002	protein histidine kinase activity
BkAM31D_RS03935	COG3212	peptidase
BkAM31D_RS03940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BkAM31D_RS03945	COG0733	neurotransmitter:sodium symporter activity
BkAM31D_RS03955	COG1704	LemA family
BkAM31D_RS03960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_RS03965	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS03970	COG0439	Biotin carboxylase
BkAM31D_RS03975	COG0511	ligase activity, forming carbon-carbon bonds
BkAM31D_RS03980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_RS03985	COG1024	Enoyl-CoA hydratase
BkAM31D_RS03995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BkAM31D_RS04020	COG4399	Belongs to the UPF0754 family
BkAM31D_RS04025	COG3679	Belongs to the UPF0342 family
BkAM31D_RS04035	COG0561	phosphatase activity
BkAM31D_RS04040	COG1368	sulfuric ester hydrolase activity
BkAM31D_RS04055	COG0706	membrane insertase activity
BkAM31D_RS04060	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS04065	COG2205	protein histidine kinase activity
BkAM31D_RS04065	COG2770	Histidine kinase
BkAM31D_RS04070	COG3481	metal-dependent phosphohydrolase, HD sub domain
BkAM31D_RS04080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BkAM31D_RS04105	COG1846	Transcriptional regulator
BkAM31D_RS04130	COG1131	(ABC) transporter
BkAM31D_RS04135	COG4473	ABC transporter
BkAM31D_RS04145	COG0785	Cytochrome C biogenesis protein
BkAM31D_RS04155	COG1842	Phage shock protein A
BkAM31D_RS04165	COG4758	membrane
BkAM31D_RS04170	COG4585	Histidine kinase
BkAM31D_RS04175	COG2197	response regulator
BkAM31D_RS04180	COG2329	Antibiotic biosynthesis monooxygenase
BkAM31D_RS04185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_RS04190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BkAM31D_RS04200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BkAM31D_RS04215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BkAM31D_RS04230	COG3290	protein histidine kinase activity
BkAM31D_RS04235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BkAM31D_RS04240	COG4492	Belongs to the UPF0735 family
BkAM31D_RS04250	COG1827	regulation of RNA biosynthetic process
BkAM31D_RS04255	COG1104	cysteine desulfurase activity
BkAM31D_RS04260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BkAM31D_RS04265	COG0157	Belongs to the NadC ModD family
BkAM31D_RS04275	COG1388	LysM domain
BkAM31D_RS04290	COG0632	four-way junction helicase activity
BkAM31D_RS04295	COG2255	four-way junction helicase activity
BkAM31D_RS04305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BkAM31D_RS04315	COG1862	Preprotein translocase
BkAM31D_RS04330	COG2323	membrane
BkAM31D_RS04335	COG2244	polysaccharide biosynthetic process
BkAM31D_RS04355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BkAM31D_RS04355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BkAM31D_RS04360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BkAM31D_RS04365	COG5416	Lipopolysaccharide assembly protein A domain
BkAM31D_RS04370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BkAM31D_RS04370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BkAM31D_RS04380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BkAM31D_RS04385	COG1490	D-aminoacyl-tRNA deacylase activity
BkAM31D_RS04390	COG0124	histidyl-tRNA synthetase
BkAM31D_RS04395	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BkAM31D_RS04400	COG0460	homoserine dehydrogenase
BkAM31D_RS04415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BkAM31D_RS04420	COG1620	l-lactate permease
BkAM31D_RS04425	COG0247	lactate metabolic process
BkAM31D_RS04430	COG1139	Iron-sulfur cluster binding protein
BkAM31D_RS04435	COG1556	Lactate utilization protein
BkAM31D_RS04450	COG2364	Membrane
BkAM31D_RS04455	COG1959	2 iron, 2 sulfur cluster binding
BkAM31D_RS04460	COG1104	cysteine desulfurase activity
BkAM31D_RS04475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BkAM31D_RS04490	COG0628	permease
BkAM31D_RS04495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BkAM31D_RS04500	COG4472	Bacterial protein of unknown function (DUF965)
BkAM31D_RS04505	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BkAM31D_RS04510	COG3906	Belongs to the UPF0473 family
BkAM31D_RS04515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BkAM31D_RS04520	COG4122	O-methyltransferase activity
BkAM31D_RS04525	COG0826	peptidase U32
BkAM31D_RS04530	COG0826	peptidase U32
BkAM31D_RS04535	COG0572	uridine kinase
BkAM31D_RS04540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BkAM31D_RS04555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BkAM31D_RS04565	COG0494	nUDIX hydrolase
BkAM31D_RS04590	COG2239	Acts as a magnesium transporter
BkAM31D_RS04595	COG1285	pathogenesis
BkAM31D_RS04600	COG2239	Acts as a magnesium transporter
BkAM31D_RS04605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BkAM31D_RS04610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BkAM31D_RS04625	COG4191	Histidine kinase
BkAM31D_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS04635	COG1966	Carbon starvation protein
BkAM31D_RS04645	COG0776	regulation of translation
BkAM31D_RS04655	COG0688	phosphatidylethanolamine metabolic process
BkAM31D_RS04660	COG3835	regulator
BkAM31D_RS04670	COG0247	lactate metabolic process
BkAM31D_RS04675	COG1320	monovalent cation:proton antiporter activity
BkAM31D_RS04680	COG2212	antiporter activity
BkAM31D_RS04685	COG1863	multisubunit Na H antiporter MnhE subunit
BkAM31D_RS04690	COG0651	ATP synthesis coupled electron transport
BkAM31D_RS04695	COG1006	Multisubunit Na H antiporter MnhC subunit
BkAM31D_RS04700	COG2111	Na H antiporter
BkAM31D_RS04705	COG2111	Na H antiporter
BkAM31D_RS04705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BkAM31D_RS04720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BkAM31D_RS04725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BkAM31D_RS04730	COG1534	Rna-binding protein
BkAM31D_RS04735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BkAM31D_RS04740	COG1713	HD superfamily hydrolase involved in NAD metabolism
BkAM31D_RS04745	COG0799	negative regulation of ribosome biogenesis
BkAM31D_RS04755	COG2226	methyltransferase
BkAM31D_RS04760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BkAM31D_RS04770	COG1555	photosystem II stabilization
BkAM31D_RS04770	COG1596	polysaccharide export
BkAM31D_RS04775	COG2131	deaminase
BkAM31D_RS04780	COG2333	competence protein COMEC
BkAM31D_RS04780	COG0658	competence protein
BkAM31D_RS04785	COG2333	competence protein COMEC
BkAM31D_RS04785	COG0658	competence protein
BkAM31D_RS04795	COG1466	dna polymerase III delta subunit
BkAM31D_RS04800	COG0268	Binds directly to 16S ribosomal RNA
BkAM31D_RS04805	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BkAM31D_RS04810	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_RS04825	COG0481	GTPase activity
BkAM31D_RS04830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BkAM31D_RS04835	COG1420	regulation of RNA biosynthetic process
BkAM31D_RS04840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BkAM31D_RS04845	COG0443	Heat shock 70 kDa protein
BkAM31D_RS04850	COG0484	heat shock protein binding
BkAM31D_RS04855	COG2264	protein methyltransferase activity
BkAM31D_RS04860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BkAM31D_RS04865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BkAM31D_RS04870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BkAM31D_RS04875	COG2205	protein histidine kinase activity
BkAM31D_RS04890	COG1283	sodium-dependent phosphate transmembrane transporter activity
BkAM31D_RS04900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BkAM31D_RS04905	COG1610	YqeY-like protein
BkAM31D_RS04915	COG4864	UPF0365 protein
BkAM31D_RS04935	COG1702	phosphate starvation-inducible protein PhoH
BkAM31D_RS04940	COG1480	7TM receptor with intracellular HD hydrolase
BkAM31D_RS04950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BkAM31D_RS04960	COG0295	cytidine deaminase activity
BkAM31D_RS04965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BkAM31D_RS04975	COG1381	Involved in DNA repair and RecF pathway recombination
BkAM31D_RS04980	COG0752	glycyl-tRNA synthetase alpha subunit
BkAM31D_RS04985	COG0751	glycine-tRNA ligase activity
BkAM31D_RS04990	COG0517	IMP dehydrogenase activity
BkAM31D_RS04995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BkAM31D_RS05000	COG1671	Belongs to the UPF0178 family
BkAM31D_RS05005	COG0358	DNA primase activity
BkAM31D_RS05010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BkAM31D_RS05015	COG2010	Cytochrome c
BkAM31D_RS05020	COG2384	SAM-dependent methyltransferase
BkAM31D_RS05025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BkAM31D_RS05030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BkAM31D_RS05045	COG0513	Belongs to the DEAD box helicase family
BkAM31D_RS05050	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BkAM31D_RS05060	COG5002	protein histidine kinase activity
BkAM31D_RS05070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BkAM31D_RS05075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BkAM31D_RS05085	COG1121	(ABC) transporter
BkAM31D_RS05090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BkAM31D_RS05095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BkAM31D_RS05100	COG0735	belongs to the Fur family
BkAM31D_RS05110	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BkAM31D_RS05115	COG4709	membrane
BkAM31D_RS05120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BkAM31D_RS05130	COG2814	Major facilitator Superfamily
BkAM31D_RS05135	COG4086	secreted protein
BkAM31D_RS05150	COG1283	sodium-dependent phosphate transmembrane transporter activity
BkAM31D_RS05180	COG1968	undecaprenyl-diphosphatase activity
BkAM31D_RS05185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BkAM31D_RS05190	COG0477	Major facilitator Superfamily
BkAM31D_RS05200	COG0768	penicillin binding
BkAM31D_RS05220	COG1543	Belongs to the glycosyl hydrolase 57 family
BkAM31D_RS05225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BkAM31D_RS05235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BkAM31D_RS05240	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BkAM31D_RS05250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BkAM31D_RS05265	COG0705	Rhomboid family
BkAM31D_RS05265	COG0457	Tetratricopeptide repeat
BkAM31D_RS05275	COG0697	spore germination
BkAM31D_RS05295	COG1940	carbohydrate kinase activity
BkAM31D_RS05300	COG1027	Aspartate ammonia-lyase
BkAM31D_RS05310	COG0352	thiamine-phosphate diphosphorylase activity
BkAM31D_RS05320	COG2022	thiamine diphosphate biosynthetic process
BkAM31D_RS05325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_RS05330	COG0351	phosphomethylpyrimidine kinase
BkAM31D_RS05340	COG0011	TIGRFAM Protein of
BkAM31D_RS05345	COG2153	protein acetylation
BkAM31D_RS05350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BkAM31D_RS05355	COG2382	esterase
BkAM31D_RS05365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BkAM31D_RS05405	COG3546	catalase activity
BkAM31D_RS05410	COG0730	response to heat
BkAM31D_RS05415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BkAM31D_RS05420	COG0765	amino acid transport
BkAM31D_RS05425	COG1126	abc transporter atp-binding protein
BkAM31D_RS05430	COG4129	membrane
BkAM31D_RS05435	COG1376	ErfK ybiS ycfS ynhG family protein
BkAM31D_RS05440	COG0346	lactoylglutathione lyase activity
BkAM31D_RS05445	COG2195	Cleaves the N-terminal amino acid of tripeptides
BkAM31D_RS05450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BkAM31D_RS05460	COG2257	FlhB HrpN YscU SpaS Family
BkAM31D_RS05475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BkAM31D_RS05480	COG1728	Protein conserved in bacteria
BkAM31D_RS05510	COG0175	sulfate reduction
BkAM31D_RS05515	COG2046	Belongs to the sulfate adenylyltransferase family
BkAM31D_RS05520	COG0306	phosphate transporter
BkAM31D_RS05525	COG0529	Catalyzes the synthesis of activated sulfate
BkAM31D_RS05530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_RS05550	COG2861	carbohydrate metabolic process
BkAM31D_RS05555	COG0789	Transcriptional regulator
BkAM31D_RS05560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BkAM31D_RS05560	COG1587	Uroporphyrinogen-III synthase
BkAM31D_RS05575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BkAM31D_RS05580	COG1469	GTP cyclohydrolase I activity
BkAM31D_RS05590	COG0527	aspartate kinase activity
BkAM31D_RS05610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BkAM31D_RS05615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BkAM31D_RS05640	COG0367	asparagine synthase
BkAM31D_RS05650	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS05660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BkAM31D_RS05675	COG2190	(PTS) system
BkAM31D_RS05680	COG3711	transcriptional antiterminator
BkAM31D_RS05685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_RS05695	COG1966	Carbon starvation protein
BkAM31D_RS05705	COG0701	Predicted permease
BkAM31D_RS05710	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BkAM31D_RS05720	COG0702	epimerase
BkAM31D_RS05730	COG1968	undecaprenyl-diphosphatase activity
BkAM31D_RS05735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_RS05755	COG1379	DNA repair
BkAM31D_RS05760	COG1300	Membrane
BkAM31D_RS05765	COG0735	belongs to the Fur family
BkAM31D_RS05775	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS05780	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BkAM31D_RS05800	COG5609	conserved protein (DUF2294)
BkAM31D_RS05810	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS05815	COG1376	ErfK ybiS ycfS ynhG family protein
BkAM31D_RS05820	COG3093	addiction module antidote protein HigA
BkAM31D_RS05840	COG5002	protein histidine kinase activity
BkAM31D_RS05855	COG1764	response to oxidative stress
BkAM31D_RS05865	COG1686	Belongs to the peptidase S11 family
BkAM31D_RS05875	COG2172	sigma factor antagonist activity
BkAM31D_RS05885	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BkAM31D_RS05890	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BkAM31D_RS05895	COG1850	ribulose-bisphosphate carboxylase activity
BkAM31D_RS05900	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BkAM31D_RS05905	COG0235	Class ii aldolase
BkAM31D_RS05910	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BkAM31D_RS05915	COG0367	asparagine synthase
BkAM31D_RS05925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_RS05940	COG0697	spore germination
BkAM31D_RS05945	COG0019	diaminopimelate decarboxylase activity
BkAM31D_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS05960	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BkAM31D_RS05965	COG1904	glucuronate isomerase
BkAM31D_RS05970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BkAM31D_RS05975	COG2755	lipolytic protein G-D-S-L family
BkAM31D_RS05990	COG2207	Transcriptional regulator
BkAM31D_RS06000	COG1653	transport
BkAM31D_RS06005	COG4209	transmembrane transport
BkAM31D_RS06010	COG0395	ABC-type sugar transport system, permease component
BkAM31D_RS06020	COG0477	Major facilitator Superfamily
BkAM31D_RS06045	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BkAM31D_RS06050	COG1653	transport
BkAM31D_RS06055	COG5578	integral membrane protein
BkAM31D_RS06060	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS06065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_RS06070	COG1609	Transcriptional regulator
BkAM31D_RS06075	COG0385	Bile acid
BkAM31D_RS06080	COG2721	sulfolactate sulfo-lyase activity
BkAM31D_RS06085	COG0246	Mannitol dehydrogenase
BkAM31D_RS06090	COG0800	Aldolase
BkAM31D_RS06095	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BkAM31D_RS06100	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_RS06135	COG3275	phosphorelay sensor kinase activity
BkAM31D_RS06140	COG3279	Response regulator of the LytR AlgR family
BkAM31D_RS06145	COG1966	Carbon starvation protein
BkAM31D_RS06175	COG1191	sigma factor activity
BkAM31D_RS06185	COG0840	transmembrane signaling receptor activity
BkAM31D_RS06195	COG0702	epimerase
BkAM31D_RS06200	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BkAM31D_RS06205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BkAM31D_RS06210	COG0561	phosphatase activity
BkAM31D_RS06215	COG2223	nitrite transmembrane transporter activity
BkAM31D_RS06225	COG1388	LysM domain
BkAM31D_RS06225	COG3584	3D domain protein
BkAM31D_RS06235	COG2112	serine threonine protein kinase
BkAM31D_RS06245	COG4326	sporulation control protein
BkAM31D_RS06255	COG1122	ATPase activity
BkAM31D_RS06260	COG4120	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS06270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BkAM31D_RS06280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BkAM31D_RS06320	COG2223	nitrite transmembrane transporter activity
BkAM31D_RS06370	COG0546	phosphoglycolate phosphatase activity
BkAM31D_RS06385	COG2962	Rard protein
BkAM31D_RS06390	COG2814	Major facilitator Superfamily
BkAM31D_RS06400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BkAM31D_RS06425	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS06430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BkAM31D_RS06440	COG1846	Transcriptional regulator
BkAM31D_RS06445	COG2814	Major facilitator Superfamily
BkAM31D_RS06460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BkAM31D_RS06465	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BkAM31D_RS06470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BkAM31D_RS06475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_RS06480	COG0589	response to stress
BkAM31D_RS06500	COG1619	proteins homologs of microcin C7 resistance protein MccF
BkAM31D_RS06505	COG1725	Transcriptional regulator
BkAM31D_RS06510	COG1131	(ABC) transporter
BkAM31D_RS06530	COG0791	NLP P60 protein
BkAM31D_RS06530	COG3883	PFAM NLP P60 protein
BkAM31D_RS06545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BkAM31D_RS06550	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BkAM31D_RS06555	COG1733	regulation of RNA biosynthetic process
BkAM31D_RS06610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_RS06665	COG0697	spore germination
BkAM31D_RS06680	COG3773	Cell wall hydrolase
BkAM31D_RS06685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BkAM31D_RS06690	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BkAM31D_RS06715	COG1063	alcohol dehydrogenase
BkAM31D_RS06725	COG1595	DNA-templated transcription, initiation
BkAM31D_RS06745	COG3773	Cell wall hydrolase
BkAM31D_RS06750	COG1063	alcohol dehydrogenase
BkAM31D_RS06755	COG5577	PFAM Coat F domain
BkAM31D_RS06770	COG5577	PFAM Coat F domain
BkAM31D_RS06820	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_RS06825	COG0717	Belongs to the dCTP deaminase family
BkAM31D_RS06860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BkAM31D_RS06865	COG3300	MHYT domain
BkAM31D_RS06865	COG5001	Diguanylate cyclase
BkAM31D_RS06880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_RS06910	COG1309	transcriptional regulator
BkAM31D_RS06920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BkAM31D_RS06925	COG0022	dehydrogenase e1 component
BkAM31D_RS06930	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_RS06935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BkAM31D_RS06960	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS06985	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BkAM31D_RS06995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS07000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS07000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS07010	COG1442	glycosyl transferase family 8
BkAM31D_RS07015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BkAM31D_RS07065	COG2112	serine threonine protein kinase
BkAM31D_RS07085	COG4555	ABC transporter
BkAM31D_RS07095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_RS07105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_RS07130	COG0583	DNA-binding transcription factor activity
BkAM31D_RS07135	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_RS07145	COG1132	(ABC) transporter
BkAM31D_RS07150	COG0435	Glutathione S-transferase
BkAM31D_RS07160	COG0346	lactoylglutathione lyase activity
BkAM31D_RS07200	COG2188	Transcriptional regulator
BkAM31D_RS07205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS07210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS07210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS07215	COG1454	alcohol dehydrogenase
BkAM31D_RS07225	COG0583	DNA-binding transcription factor activity
BkAM31D_RS07240	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_RS07255	COG0371	Dehydrogenase
BkAM31D_RS07270	COG2011	ABC-type metal ion transport system permease component
BkAM31D_RS07285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_RS07285	COG2190	(PTS) system
BkAM31D_RS07285	COG1263	PTS System
BkAM31D_RS07290	COG2207	Transcriptional regulator
BkAM31D_RS07290	COG4753	response regulator
BkAM31D_RS07295	COG3250	beta-galactosidase activity
BkAM31D_RS07320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BkAM31D_RS07330	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
BkAM31D_RS07335	COG3052	prosthetic group binding
BkAM31D_RS07360	COG0656	L-ascorbic acid biosynthetic process
BkAM31D_RS07375	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BkAM31D_RS07375	COG2885	chlorophyll binding
BkAM31D_RS07395	COG1802	Transcriptional regulator
BkAM31D_RS07400	COG2084	Dehydrogenase
BkAM31D_RS07415	COG0191	fructose-bisphosphate aldolase activity
BkAM31D_RS07430	COG2972	Histidine kinase
BkAM31D_RS07435	COG2207	Transcriptional regulator
BkAM31D_RS07435	COG4753	response regulator
BkAM31D_RS07450	COG4122	O-methyltransferase activity
BkAM31D_RS07485	COG1175	transmembrane transport
BkAM31D_RS07490	COG0395	ABC-type sugar transport system, permease component
BkAM31D_RS07500	COG1621	beta-fructofuranosidase activity
BkAM31D_RS07510	COG1131	(ABC) transporter
BkAM31D_RS07515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BkAM31D_RS07520	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS07525	COG5002	protein histidine kinase activity
BkAM31D_RS07530	COG2814	Major facilitator Superfamily
BkAM31D_RS07535	COG0702	epimerase
BkAM31D_RS07540	COG1959	2 iron, 2 sulfur cluster binding
BkAM31D_RS07550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_RS07560	COG1737	Transcriptional regulator
BkAM31D_RS07565	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BkAM31D_RS07570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS07575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS07575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS07595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BkAM31D_RS07600	COG0363	glucosamine-6-phosphate deaminase activity
BkAM31D_RS07605	COG0842	Transport permease protein
BkAM31D_RS07610	COG1131	(ABC) transporter
BkAM31D_RS07615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BkAM31D_RS07630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BkAM31D_RS07635	COG0400	carboxylic ester hydrolase activity
BkAM31D_RS07640	COG2259	Doxx family
BkAM31D_RS07645	COG0655	NAD(P)H dehydrogenase (quinone) activity
BkAM31D_RS07655	COG4682	membrane
BkAM31D_RS07665	COG1131	(ABC) transporter
BkAM31D_RS07685	COG1054	Belongs to the UPF0176 family
BkAM31D_RS07695	COG0196	riboflavin kinase activity
BkAM31D_RS07730	COG3180	Ammonia monooxygenase
BkAM31D_RS07740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS07745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS07770	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS07770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS07780	COG2204	response regulator
BkAM31D_RS07785	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS07795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_RS07800	COG2181	nitrate reductase activity
BkAM31D_RS07800	COG0247	lactate metabolic process
BkAM31D_RS07805	COG0154	amidase activity
BkAM31D_RS07810	COG0456	acetyltransferase
BkAM31D_RS07825	COG1414	Transcriptional regulator
BkAM31D_RS07830	COG2807	transmembrane transport
BkAM31D_RS07835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BkAM31D_RS07845	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_RS07865	COG0659	secondary active sulfate transmembrane transporter activity
BkAM31D_RS07880	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BkAM31D_RS07895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BkAM31D_RS07900	COG0747	negative chemotaxis
BkAM31D_RS07905	COG2843	Capsule synthesis protein
BkAM31D_RS07925	COG0477	Major facilitator Superfamily
BkAM31D_RS07945	COG2843	Capsule synthesis protein
BkAM31D_RS07955	COG0747	negative chemotaxis
BkAM31D_RS07965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_RS08000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS08020	COG2508	Transcriptional regulator
BkAM31D_RS08030	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS08035	COG0183	Belongs to the thiolase family
BkAM31D_RS08040	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_RS08050	COG0569	domain protein
BkAM31D_RS08075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS08090	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BkAM31D_RS08095	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BkAM31D_RS08105	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS08110	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_RS08115	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_RS08145	COG2072	flavoprotein involved in K transport
BkAM31D_RS08175	COG1131	(ABC) transporter
BkAM31D_RS08185	COG1024	Enoyl-CoA hydratase
BkAM31D_RS08235	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS08245	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS08250	COG0183	Belongs to the thiolase family
BkAM31D_RS08255	COG2086	electron transfer activity
BkAM31D_RS08260	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_RS08265	COG2050	protein possibly involved in aromatic compounds catabolism
BkAM31D_RS08270	COG3829	transcription factor binding
BkAM31D_RS08270	COG3290	protein histidine kinase activity
BkAM31D_RS08280	COG1024	Enoyl-CoA hydratase
BkAM31D_RS08285	COG0521	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_RS08300	COG0523	cobalamin synthesis protein
BkAM31D_RS08330	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BkAM31D_RS08370	COG0778	Nitroreductase
BkAM31D_RS08385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_RS08395	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BkAM31D_RS08400	COG1492	cobalamin metabolic process
BkAM31D_RS08410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BkAM31D_RS08430	COG2755	lipolytic protein G-D-S-L family
BkAM31D_RS08445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BkAM31D_RS08450	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_RS08450	COG3773	Cell wall hydrolase
BkAM31D_RS08465	COG1414	Transcriptional regulator
BkAM31D_RS08470	COG1414	Transcriptional regulator
BkAM31D_RS08480	COG0733	neurotransmitter:sodium symporter activity
BkAM31D_RS08485	COG3483	tryptophan 2,3-dioxygenase activity
BkAM31D_RS08495	COG3844	kynureninase activity
BkAM31D_RS08500	COG1309	transcriptional regulator
BkAM31D_RS08510	COG0784	Response regulator, receiver
BkAM31D_RS08515	COG4191	Histidine kinase
BkAM31D_RS08520	COG1115	amino acid carrier protein
BkAM31D_RS08530	COG1396	sequence-specific DNA binding
BkAM31D_RS08535	COG2066	Belongs to the glutaminase family
BkAM31D_RS08540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_RS08560	COG2814	Major facilitator Superfamily
BkAM31D_RS08565	COG2211	Major facilitator Superfamily
BkAM31D_RS08585	COG0789	Transcriptional regulator
BkAM31D_RS08595	COG1131	(ABC) transporter
BkAM31D_RS08610	COG4585	Histidine kinase
BkAM31D_RS08615	COG2197	response regulator
BkAM31D_RS08660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BkAM31D_RS08665	COG2755	lipolytic protein G-D-S-L family
BkAM31D_RS08670	COG0393	Putative heavy-metal-binding
BkAM31D_RS08715	COG2972	Histidine kinase
BkAM31D_RS08720	COG2169	Transcriptional regulator
BkAM31D_RS08730	COG1621	beta-fructofuranosidase activity
BkAM31D_RS08740	COG1621	beta-fructofuranosidase activity
BkAM31D_RS08755	COG2182	Extracellular solute-binding protein
BkAM31D_RS08760	COG1175	transmembrane transport
BkAM31D_RS08765	COG0395	ABC-type sugar transport system, permease component
BkAM31D_RS08770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_RS08775	COG5578	integral membrane protein
BkAM31D_RS08785	COG1621	beta-fructofuranosidase activity
BkAM31D_RS08795	COG2181	nitrate reductase activity
BkAM31D_RS08795	COG0247	lactate metabolic process
BkAM31D_RS08815	COG0515	serine threonine protein kinase
BkAM31D_RS08815	COG2815	serine threonine protein kinase
BkAM31D_RS08880	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BkAM31D_RS08910	COG0827	DNA restriction-modification system
BkAM31D_RS08925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_RS08955	COG2433	Pfam Transposase IS66
BkAM31D_RS08960	COG0210	DNA helicase
BkAM31D_RS09005	COG2176	DNA-directed DNA polymerase activity
BkAM31D_RS09010	COG1609	Transcriptional regulator
BkAM31D_RS09015	COG1879	ABC-type sugar transport system periplasmic component
BkAM31D_RS09030	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS09035	COG2376	Dihydroxyacetone kinase
BkAM31D_RS09045	COG2207	Transcriptional regulator
BkAM31D_RS09045	COG4753	response regulator
BkAM31D_RS09050	COG2972	Histidine kinase
BkAM31D_RS09065	COG1175	transmembrane transport
BkAM31D_RS09070	COG0395	ABC-type sugar transport system, permease component
BkAM31D_RS09095	COG5564	TIM-barrel signal transduction protein
BkAM31D_RS09105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS09110	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_RS09135	COG1278	Cold shock
BkAM31D_RS09160	COG2814	Major facilitator Superfamily
BkAM31D_RS09165	COG0534	Mate efflux family protein
BkAM31D_RS09170	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BkAM31D_RS09175	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_RS09180	COG3284	Transcriptional regulator
BkAM31D_RS09190	COG0022	dehydrogenase e1 component
BkAM31D_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS09225	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_RS09230	COG4980	gas vesicle protein
BkAM31D_RS09235	COG0011	TIGRFAM Protein of
BkAM31D_RS09265	COG2208	phosphoserine phosphatase activity
BkAM31D_RS09270	COG0596	Alpha beta hydrolase
BkAM31D_RS09275	COG0243	molybdopterin cofactor binding
BkAM31D_RS09285	COG4191	Histidine kinase
BkAM31D_RS09300	COG0840	transmembrane signaling receptor activity
BkAM31D_RS09305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BkAM31D_RS09325	COG1388	LysM domain
BkAM31D_RS09325	COG0791	NLP P60 protein
BkAM31D_RS09335	COG0814	amino acid
BkAM31D_RS09345	COG0697	spore germination
BkAM31D_RS09360	COG0179	Fumarylacetoacetate (FAA) hydrolase
BkAM31D_RS09480	COG0583	DNA-binding transcription factor activity
BkAM31D_RS09525	COG0733	neurotransmitter:sodium symporter activity
BkAM31D_RS09530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BkAM31D_RS09545	COG0114	fumarate hydratase activity
BkAM31D_RS09555	COG2226	methyltransferase
BkAM31D_RS09560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BkAM31D_RS09565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BkAM31D_RS09565	COG3153	acetyltransferase
BkAM31D_RS09570	COG0456	acetyltransferase
BkAM31D_RS09580	COG1733	regulation of RNA biosynthetic process
BkAM31D_RS09585	COG2514	catechol 2,3-dioxygenase activity
BkAM31D_RS09590	COG2259	Doxx family
BkAM31D_RS09600	COG1473	amidohydrolase
BkAM31D_RS09625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_RS09630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BkAM31D_RS09630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BkAM31D_RS09635	COG0307	riboflavin synthase, alpha
BkAM31D_RS09640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_RS09640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_RS09645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BkAM31D_RS09660	COG0456	acetyltransferase
BkAM31D_RS09665	COG1547	Domain of unknown function (DUF309)
BkAM31D_RS09675	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BkAM31D_RS09680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BkAM31D_RS09690	COG2323	membrane
BkAM31D_RS09710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_RS09725	COG2323	membrane
BkAM31D_RS09735	COG1686	Belongs to the peptidase S11 family
BkAM31D_RS09740	COG2715	membrane protein required for spore maturation
BkAM31D_RS09745	COG0700	Nucleoside recognition
BkAM31D_RS09755	COG1187	pseudouridine synthase activity
BkAM31D_RS09760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_RS09770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BkAM31D_RS09775	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS09785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BkAM31D_RS09790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BkAM31D_RS09795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_RS09805	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BkAM31D_RS09810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BkAM31D_RS09815	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BkAM31D_RS09820	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BkAM31D_RS09835	COG2096	Adenosyltransferase
BkAM31D_RS09840	COG2720	vancomycin resistance protein
BkAM31D_RS09860	COG0739	heme binding
BkAM31D_RS09875	COG2186	Transcriptional regulator
BkAM31D_RS09880	COG1141	Ferredoxin
BkAM31D_RS09885	COG4955	Helix-turn-helix domain
BkAM31D_RS09890	COG0514	ATP-dependent DNA helicase (RecQ)
BkAM31D_RS09895	COG1266	CAAX protease self-immunity
BkAM31D_RS09925	COG1408	metallophosphoesterase
BkAM31D_RS09935	COG4862	establishment of competence for transformation
BkAM31D_RS09940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_RS09945	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_RS09950	COG0252	asparaginase activity
BkAM31D_RS09955	COG2339	peptidase activity
BkAM31D_RS09960	COG0626	cystathionine gamma-synthase activity
BkAM31D_RS09965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BkAM31D_RS09965	COG0646	methionine synthase
BkAM31D_RS09970	COG0646	methionine synthase
BkAM31D_RS09970	COG1410	methionine synthase
BkAM31D_RS09975	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_RS09975	COG3773	Cell wall hydrolase
BkAM31D_RS09990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BkAM31D_RS09995	COG0204	Acyl-transferase
BkAM31D_RS10000	COG0539	negative regulation of cytoplasmic translation
BkAM31D_RS10005	COG1304	FMN binding
BkAM31D_RS10020	COG1160	GTP binding
BkAM31D_RS10025	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BkAM31D_RS10030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BkAM31D_RS10050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BkAM31D_RS10060	COG0142	geranyltranstransferase activity
BkAM31D_RS10065	COG2226	methyltransferase
BkAM31D_RS10075	COG0163	prenyltransferase activity
BkAM31D_RS10080	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BkAM31D_RS10085	COG0142	geranyltranstransferase activity
BkAM31D_RS10090	COG0105	UTP biosynthetic process
BkAM31D_RS10095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BkAM31D_RS10105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BkAM31D_RS10110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BkAM31D_RS10115	COG4401	Chorismate mutase type I
BkAM31D_RS10120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BkAM31D_RS10125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BkAM31D_RS10130	COG0134	indole-3-glycerol-phosphate synthase activity
BkAM31D_RS10135	COG0135	phosphoribosylanthranilate isomerase activity
BkAM31D_RS10140	COG0133	tryptophan synthase activity
BkAM31D_RS10145	COG0159	tryptophan synthase activity
BkAM31D_RS10150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BkAM31D_RS10155	COG0287	Prephenate dehydrogenase
BkAM31D_RS10160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BkAM31D_RS10170	COG0457	Tetratricopeptide repeat
BkAM31D_RS10175	COG5582	Belongs to the UPF0302 family
BkAM31D_RS10185	COG0723	plastoquinol--plastocyanin reductase activity
BkAM31D_RS10190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BkAM31D_RS10195	COG2010	Cytochrome c
BkAM31D_RS10195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BkAM31D_RS10200	COG4347	Protein of unknown function (DUF1405)
BkAM31D_RS10210	COG2738	Putative neutral zinc metallopeptidase
BkAM31D_RS10215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_RS10220	COG1694	Mazg nucleotide pyrophosphohydrolase
BkAM31D_RS10225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BkAM31D_RS10230	COG1803	Methylglyoxal synthase
BkAM31D_RS10235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BkAM31D_RS10240	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_RS10245	COG0617	tRNA 3'-terminal CCA addition
BkAM31D_RS10265	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BkAM31D_RS10295	COG0436	Aminotransferase
BkAM31D_RS10300	COG0017	Asparaginyl-tRNA synthetase
BkAM31D_RS10305	COG3935	DnaD domain protein
BkAM31D_RS10310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BkAM31D_RS10320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BkAM31D_RS10330	COG4499	WXG100 protein secretion system (Wss), protein YukC
BkAM31D_RS10330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_RS10335	COG3331	DNA recombination
BkAM31D_RS10345	COG0789	Transcriptional regulator
BkAM31D_RS10365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BkAM31D_RS10375	COG0693	protein deglycase activity
BkAM31D_RS10380	COG1234	tRNA 3'-trailer cleavage
BkAM31D_RS10390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_RS10410	COG1413	lyase activity
BkAM31D_RS10420	COG3402	PFAM membrane-flanked domain
BkAM31D_RS10425	COG3428	Bacterial PH domain
BkAM31D_RS10460	COG0493	'glutamate synthase
BkAM31D_RS10470	COG2124	cytochrome p450
BkAM31D_RS10505	COG2508	Transcriptional regulator
BkAM31D_RS10520	COG1473	amidohydrolase
BkAM31D_RS10525	COG0460	homoserine dehydrogenase
BkAM31D_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS10535	COG0006	proline dipeptidase activity
BkAM31D_RS10540	COG0697	spore germination
BkAM31D_RS10545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BkAM31D_RS10575	COG1278	Cold shock
BkAM31D_RS10580	COG0768	penicillin binding
BkAM31D_RS10585	COG0768	penicillin binding
BkAM31D_RS10600	COG1111	helicase
BkAM31D_RS10600	COG1205	dead DEAH box helicase
BkAM31D_RS10605	COG3359	exonuclease
BkAM31D_RS10615	COG4474	Belongs to the UPF0398 family
BkAM31D_RS10620	COG3599	regulation of cell shape
BkAM31D_RS10625	COG0328	RNA-DNA hybrid ribonuclease activity
BkAM31D_RS10635	COG0116	Belongs to the methyltransferase superfamily
BkAM31D_RS10680	COG2188	Transcriptional regulator
BkAM31D_RS10685	COG1131	(ABC) transporter
BkAM31D_RS10690	COG5522	Integral membrane protein (intg_mem_TP0381)
BkAM31D_RS10700	COG4294	response to UV
BkAM31D_RS10705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_RS10710	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BkAM31D_RS10715	COG0535	radical SAM domain protein
BkAM31D_RS10735	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BkAM31D_RS10740	COG1116	anion transmembrane transporter activity
BkAM31D_RS10745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_RS10750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BkAM31D_RS10755	COG0671	phosphoesterase, PA-phosphatase related
BkAM31D_RS10770	COG0583	DNA-binding transcription factor activity
BkAM31D_RS10775	COG3829	transcription factor binding
BkAM31D_RS10775	COG3290	protein histidine kinase activity
BkAM31D_RS10785	COG2610	gluconate transmembrane transporter activity
BkAM31D_RS10790	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS10795	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS10800	COG3118	belongs to the thioredoxin family
BkAM31D_RS10815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_RS10815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_RS10835	COG1832	CoA-binding protein
BkAM31D_RS10840	COG0187	DNA topoisomerase II activity
BkAM31D_RS10845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BkAM31D_RS10850	COG1988	membrane-bound metal-dependent
BkAM31D_RS10855	COG0205	6-phosphofructokinase activity
BkAM31D_RS10880	COG2027	D-alanyl-D-alanine carboxypeptidase
BkAM31D_RS10895	COG2720	vancomycin resistance protein
BkAM31D_RS10915	COG0431	NADPH-dependent FMN reductase
BkAM31D_RS10920	COG1846	Transcriptional regulator
BkAM31D_RS10945	COG1063	alcohol dehydrogenase
BkAM31D_RS10950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BkAM31D_RS10985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BkAM31D_RS10995	COG2223	nitrite transmembrane transporter activity
BkAM31D_RS11005	COG2146	nitrite reductase [NAD(P)H] activity
BkAM31D_RS11015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BkAM31D_RS11020	COG1151	hydroxylamine reductase activity
BkAM31D_RS11025	COG2860	membrane
BkAM31D_RS11030	COG3835	regulator
BkAM31D_RS11045	COG1473	amidohydrolase
BkAM31D_RS11065	COG5002	protein histidine kinase activity
BkAM31D_RS11070	COG2357	RelA SpoT domain protein
BkAM31D_RS11080	COG0326	Molecular chaperone. Has ATPase activity
BkAM31D_RS11100	COG2433	Pfam Transposase IS66
BkAM31D_RS11105	COG3594	Acyltransferase
BkAM31D_RS11120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BkAM31D_RS11125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BkAM31D_RS11135	COG0640	Transcriptional regulator
BkAM31D_RS11140	COG0024	Methionine aminopeptidase
BkAM31D_RS11155	COG0489	protein tyrosine kinase activity
BkAM31D_RS11160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_RS11180	COG0437	4 iron, 4 sulfur cluster binding
BkAM31D_RS11195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_RS11205	COG0436	Aminotransferase
BkAM31D_RS11220	COG1278	Cold shock
BkAM31D_RS11240	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BkAM31D_RS11245	COG2323	membrane
BkAM31D_RS11250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_RS11255	COG0583	DNA-binding transcription factor activity
BkAM31D_RS11260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BkAM31D_RS11265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BkAM31D_RS11270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS11275	COG1454	alcohol dehydrogenase
BkAM31D_RS11285	COG3852	Histidine kinase
BkAM31D_RS11290	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS11305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_RS11325	COG0542	response to heat
BkAM31D_RS11335	COG0768	penicillin binding
BkAM31D_RS11350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BkAM31D_RS11365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BkAM31D_RS11375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_RS11385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BkAM31D_RS11395	COG1509	lysine 2,3-aminomutase activity
BkAM31D_RS11400	COG0456	acetyltransferase
BkAM31D_RS11405	COG3829	transcription factor binding
BkAM31D_RS11410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BkAM31D_RS11415	COG3858	chitin binding
BkAM31D_RS11415	COG1388	LysM domain
BkAM31D_RS11430	COG0778	Nitroreductase
BkAM31D_RS11455	COG0514	ATP-dependent DNA helicase (RecQ)
BkAM31D_RS11460	COG0704	Plays a role in the regulation of phosphate uptake
BkAM31D_RS11475	COG1744	ABC transporter substrate-binding protein PnrA-like
BkAM31D_RS11495	COG3559	Exporter of polyketide antibiotics
BkAM31D_RS11500	COG1131	(ABC) transporter
BkAM31D_RS11510	COG1278	Cold shock
BkAM31D_RS11535	COG4536	flavin adenine dinucleotide binding
BkAM31D_RS11540	COG1959	2 iron, 2 sulfur cluster binding
BkAM31D_RS11555	COG2271	Major facilitator Superfamily
BkAM31D_RS11620	COG1937	Protein conserved in bacteria
BkAM31D_RS11625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BkAM31D_RS11650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BkAM31D_RS11665	COG1119	ATPase activity
BkAM31D_RS11685	COG3011	Protein conserved in bacteria
BkAM31D_RS11690	COG2258	MOSC domain
BkAM31D_RS11695	COG0708	Exodeoxyribonuclease III
BkAM31D_RS11700	COG1834	amidinotransferase
BkAM31D_RS11720	COG1113	amino acid transport
BkAM31D_RS11725	COG1280	lysine exporter protein (LysE YggA)
BkAM31D_RS11740	COG1164	Oligoendopeptidase f
BkAM31D_RS11750	COG1595	DNA-templated transcription, initiation
BkAM31D_RS11755	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS11765	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BkAM31D_RS11805	COG0730	response to heat
BkAM31D_RS11810	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS11815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS11820	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11830	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS11835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS11845	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11850	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11855	COG1937	Protein conserved in bacteria
BkAM31D_RS11885	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS11890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS11895	COG2210	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11900	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS11905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS11905	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS11915	COG1183	phosphatidylcholine synthase activity
BkAM31D_RS11920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BkAM31D_RS11925	COG0517	IMP dehydrogenase activity
BkAM31D_RS11935	COG2223	nitrite transmembrane transporter activity
BkAM31D_RS11940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BkAM31D_RS11945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BkAM31D_RS11950	COG2226	methyltransferase
BkAM31D_RS11960	COG1285	pathogenesis
BkAM31D_RS11965	COG2340	Cysteine-rich secretory protein family
BkAM31D_RS11970	COG3973	AAA domain
BkAM31D_RS11980	COG0400	carboxylic ester hydrolase activity
BkAM31D_RS11995	COG1011	Hydrolase
BkAM31D_RS12000	COG1199	ATP-dependent helicase activity
BkAM31D_RS12020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_RS12030	COG0300	oxidoreductase activity
BkAM31D_RS12040	COG0697	spore germination
BkAM31D_RS12045	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BkAM31D_RS12070	COG2105	PFAM AIG2 family protein
BkAM31D_RS12075	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_RS12100	COG4895	conserved protein (DUF2196)
BkAM31D_RS12105	COG2217	Heavy metal translocating P-type atpase
BkAM31D_RS12110	COG2608	mercury ion transmembrane transporter activity
BkAM31D_RS12115	COG1937	Protein conserved in bacteria
BkAM31D_RS12130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BkAM31D_RS12135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BkAM31D_RS12150	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BkAM31D_RS12170	COG1307	EDD domain protein, DegV family
BkAM31D_RS12175	COG0514	ATP-dependent DNA helicase (RecQ)
BkAM31D_RS12185	COG0488	(ABC) transporter
BkAM31D_RS12190	COG0697	spore germination
BkAM31D_RS12195	COG0586	Pfam SNARE associated Golgi protein
BkAM31D_RS12205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_RS12210	COG0567	Dehydrogenase, E1 component
BkAM31D_RS12240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BkAM31D_RS12245	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_RS12250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BkAM31D_RS12255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BkAM31D_RS12260	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_RS12270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BkAM31D_RS12410	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_RS12500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BkAM31D_RS12510	COG0720	synthase
BkAM31D_RS12515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BkAM31D_RS12520	COG2309	aminopeptidase activity
BkAM31D_RS12535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BkAM31D_RS12545	COG4841	protein insertion into membrane
BkAM31D_RS12550	COG0784	Response regulator, receiver
BkAM31D_RS12550	COG0835	chemotaxis
BkAM31D_RS12585	COG2200	EAL domain
BkAM31D_RS12590	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BkAM31D_RS12595	COG0328	RNA-DNA hybrid ribonuclease activity
BkAM31D_RS12600	COG1666	GTP binding
BkAM31D_RS12605	COG0613	PHP domain protein
BkAM31D_RS12615	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BkAM31D_RS12630	COG0824	Thioesterase
BkAM31D_RS12635	COG0464	growth
BkAM31D_RS12640	COG0697	spore germination
BkAM31D_RS12655	COG0398	Pfam SNARE associated Golgi protein
BkAM31D_RS12675	COG2323	membrane
BkAM31D_RS12680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BkAM31D_RS12695	COG1607	acyl-coa hydrolase
BkAM31D_RS12715	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BkAM31D_RS12745	COG1228	amidohydrolase
BkAM31D_RS12755	COG2986	histidine ammonia-lyase
BkAM31D_RS12770	COG3314	Sporulation integral membrane protein YlbJ
BkAM31D_RS12800	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_RS12810	COG0385	Bile acid
BkAM31D_RS12835	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_RS12845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_RS12850	COG0601	transmembrane transport
BkAM31D_RS12870	COG0477	Major facilitator Superfamily
BkAM31D_RS12885	COG2340	Cysteine-rich secretory protein family
BkAM31D_RS12890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_RS12910	COG0626	cystathionine gamma-synthase activity
BkAM31D_RS12930	COG2267	carboxylic ester hydrolase activity
BkAM31D_RS12935	COG0671	phosphoesterase, PA-phosphatase related
BkAM31D_RS12970	COG4846	Membrane protein involved in cytochrome C biogenesis
BkAM31D_RS12975	COG1132	(ABC) transporter
BkAM31D_RS12980	COG1132	(ABC) transporter
BkAM31D_RS12985	COG3763	UPF0154 protein
BkAM31D_RS12995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BkAM31D_RS13000	COG4224	UPF0291 protein
BkAM31D_RS13005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_RS13015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BkAM31D_RS13030	COG0174	glutamine synthetase
BkAM31D_RS13035	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BkAM31D_RS13040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BkAM31D_RS13060	COG1923	regulation of RNA biosynthetic process
BkAM31D_RS13065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BkAM31D_RS13070	COG2136	Putative SAM-dependent methyltransferase
BkAM31D_RS13070	COG2521	methyltransferase
BkAM31D_RS13075	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BkAM31D_RS13080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BkAM31D_RS13090	COG4550	Control of competence regulator ComK, YlbF/YmcA
BkAM31D_RS13095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BkAM31D_RS13100	COG1013	pyruvate-flavodoxin oxidoreductase activity
BkAM31D_RS13110	COG0697	spore germination
BkAM31D_RS13135	COG1692	metallophosphoesterase
BkAM31D_RS13140	COG1418	mRNA catabolic process
BkAM31D_RS13155	COG0497	DNA recombination
BkAM31D_RS13165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BkAM31D_RS13170	COG0513	Belongs to the DEAD box helicase family
BkAM31D_RS13175	COG1058	Belongs to the CinA family
BkAM31D_RS13175	COG1546	Belongs to the CinA family
BkAM31D_RS13180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BkAM31D_RS13185	COG1426	Protein conserved in bacteria
BkAM31D_RS13200	COG0300	oxidoreductase activity
BkAM31D_RS13205	COG0612	Peptidase, M16
BkAM31D_RS13210	COG0612	Peptidase, M16
BkAM31D_RS13215	COG2188	Transcriptional regulator
BkAM31D_RS13220	COG1674	ftsk spoiiie
BkAM31D_RS13230	COG0740	serine-type endopeptidase activity
BkAM31D_RS13240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BkAM31D_RS13245	COG0527	aspartate kinase activity
BkAM31D_RS13250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BkAM31D_RS13255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BkAM31D_RS13260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BkAM31D_RS13265	COG1873	PFAM PRC-barrel domain
BkAM31D_RS13270	COG0612	Peptidase, M16
BkAM31D_RS13280	COG1185	polyribonucleotide nucleotidyltransferase activity
BkAM31D_RS13285	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BkAM31D_RS13290	COG0196	riboflavin kinase activity
BkAM31D_RS13295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BkAM31D_RS13300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BkAM31D_RS13310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BkAM31D_RS13315	COG1358	cellular component organization or biogenesis
BkAM31D_RS13320	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BkAM31D_RS13325	COG0195	Participates in both transcription termination and antitermination
BkAM31D_RS13330	COG0779	Required for maturation of 30S ribosomal subunits
BkAM31D_RS13340	COG0442	prolyl-tRNA aminoacylation
BkAM31D_RS13345	COG0750	zinc metalloprotease
BkAM31D_RS13350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BkAM31D_RS13355	COG4589	Belongs to the CDS family
BkAM31D_RS13360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BkAM31D_RS13365	COG0233	cytoplasmic translational termination
BkAM31D_RS13370	COG0528	UMP kinase activity
BkAM31D_RS13375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BkAM31D_RS13380	COG0052	Belongs to the universal ribosomal protein uS2 family
BkAM31D_RS13390	COG1191	sigma factor activity
BkAM31D_RS13395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BkAM31D_RS13405	COG2201	protein-glutamate methylesterase activity
BkAM31D_RS13415	COG1419	protein localization to endoplasmic reticulum
BkAM31D_RS13420	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BkAM31D_RS13425	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BkAM31D_RS13430	COG1684	flagellar biosynthetic protein fliR
BkAM31D_RS13435	COG1987	bacterial-type flagellum assembly
BkAM31D_RS13440	COG1338	Plays a role in the flagellum-specific transport system
BkAM31D_RS13445	COG3190	flagellar
BkAM31D_RS13450	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BkAM31D_RS13450	COG1776	CheC inhibitor of MCP methylation
BkAM31D_RS13455	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BkAM31D_RS13465	COG1582	Flagellar protein (FlbD)
BkAM31D_RS13470	COG4786	Flagellar basal body rod
BkAM31D_RS13480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BkAM31D_RS13495	COG2882	bacterial-type flagellum organization
BkAM31D_RS13500	COG1157	protein secretion by the type III secretion system
BkAM31D_RS13510	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BkAM31D_RS13515	COG1766	The M ring may be actively involved in energy transduction
BkAM31D_RS13520	COG1677	Flagellar hook-basal body complex protein FliE
BkAM31D_RS13525	COG1558	bacterial-type flagellum-dependent cell motility
BkAM31D_RS13530	COG1815	bacterial-type flagellum-dependent cell motility
BkAM31D_RS13535	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BkAM31D_RS13540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BkAM31D_RS13545	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BkAM31D_RS13550	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS13555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BkAM31D_RS13560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BkAM31D_RS13565	COG0758	DNA mediated transformation
BkAM31D_RS13570	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BkAM31D_RS13575	COG0045	succinate-CoA ligase (ADP-forming) activity
BkAM31D_RS13580	COG2257	FlhB HrpN YscU SpaS Family
BkAM31D_RS13590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BkAM31D_RS13605	COG0335	large ribosomal subunit rRNA binding
BkAM31D_RS13610	COG0336	Belongs to the RNA methyltransferase TrmD family
BkAM31D_RS13615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BkAM31D_RS13625	COG1837	Belongs to the UPF0109 family
BkAM31D_RS13630	COG0228	four-way junction DNA binding
BkAM31D_RS13635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BkAM31D_RS13640	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BkAM31D_RS13645	COG0552	protein localization to endoplasmic reticulum
BkAM31D_RS13650	COG1196	nuclear chromosome segregation
BkAM31D_RS13655	COG4840	Belongs to the UPF0435 family
BkAM31D_RS13660	COG0571	ribonuclease III activity
BkAM31D_RS13665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BkAM31D_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS13675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BkAM31D_RS13680	COG0416	fatty acid biosynthetic process
BkAM31D_RS13685	COG1349	DNA-binding transcription factor activity
BkAM31D_RS13690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BkAM31D_RS13695	COG1760	l-serine dehydratase
BkAM31D_RS13700	COG1760	l-serine dehydratase
BkAM31D_RS13705	COG1307	EDD domain protein, DegV family
BkAM31D_RS13710	COG1461	Dihydroxyacetone kinase
BkAM31D_RS13715	COG1302	Protein conserved in bacteria
BkAM31D_RS13720	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BkAM31D_RS13730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BkAM31D_RS13735	COG1162	GTPase activity
BkAM31D_RS13740	COG0515	serine threonine protein kinase
BkAM31D_RS13740	COG2815	serine threonine protein kinase
BkAM31D_RS13745	COG0631	protein serine/threonine phosphatase activity
BkAM31D_RS13750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BkAM31D_RS13755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BkAM31D_RS13755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BkAM31D_RS13760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BkAM31D_RS13765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BkAM31D_RS13770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BkAM31D_RS13775	COG1758	RNA polymerase activity
BkAM31D_RS13780	COG0194	GDP metabolic process
BkAM31D_RS13785	COG2052	Domain of unknown function (DUF370)
BkAM31D_RS13790	COG1561	YicC-like family, N-terminal region
BkAM31D_RS13805	COG2226	methyltransferase
BkAM31D_RS13810	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BkAM31D_RS13815	COG0284	orotidine-5'-phosphate decarboxylase activity
BkAM31D_RS13820	COG0167	dihydroorotate dehydrogenase activity
BkAM31D_RS13825	COG0543	2 iron, 2 sulfur cluster binding
BkAM31D_RS13830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BkAM31D_RS13835	COG0505	Belongs to the CarA family
BkAM31D_RS13840	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BkAM31D_RS13845	COG0540	Belongs to the ATCase OTCase family
BkAM31D_RS13850	COG2233	PERMEase
BkAM31D_RS13855	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BkAM31D_RS13860	COG0564	pseudouridine synthase activity
BkAM31D_RS13865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BkAM31D_RS13870	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BkAM31D_RS13875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BkAM31D_RS13880	COG3599	regulation of cell shape
BkAM31D_RS13885	COG2302	S4 RNA-binding domain
BkAM31D_RS13890	COG0762	integral membrane protein
BkAM31D_RS13895	COG1799	cell septum assembly
BkAM31D_RS13900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BkAM31D_RS13905	COG1496	oxidoreductase activity
BkAM31D_RS13910	COG1873	PFAM PRC-barrel domain
BkAM31D_RS13915	COG1191	sigma factor activity
BkAM31D_RS13920	COG1191	sigma factor activity
BkAM31D_RS13930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BkAM31D_RS13935	COG0849	cell division
BkAM31D_RS13940	COG3856	small basic protein
BkAM31D_RS13945	COG3879	Bacterial protein of unknown function (DUF881)
BkAM31D_RS13950	COG3879	Bacterial protein of unknown function (DUF881)
BkAM31D_RS13955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BkAM31D_RS13960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BkAM31D_RS13965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BkAM31D_RS13970	COG0772	Belongs to the SEDS family
BkAM31D_RS13980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BkAM31D_RS13985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BkAM31D_RS13990	COG0768	penicillin binding
BkAM31D_RS13995	COG0768	penicillin binding
BkAM31D_RS14005	COG0275	rRNA processing
BkAM31D_RS14010	COG2001	Belongs to the MraZ family
BkAM31D_RS14015	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BkAM31D_RS14025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BkAM31D_RS14030	COG0454	-acetyltransferase
BkAM31D_RS14040	COG1024	Enoyl-CoA hydratase
BkAM31D_RS14045	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BkAM31D_RS14055	COG1323	Belongs to the UPF0348 family
BkAM31D_RS14060	COG3480	Lon protease (S16) C-terminal proteolytic domain
BkAM31D_RS14065	COG1752	Esterase of the alpha-beta hydrolase superfamily
BkAM31D_RS14070	COG3314	Sporulation integral membrane protein YlbJ
BkAM31D_RS14080	COG0742	ribosomal rna small subunit methyltransferase
BkAM31D_RS14095	COG4471	UPF0298 protein
BkAM31D_RS14105	COG3679	Belongs to the UPF0342 family
BkAM31D_RS14110	COG4294	response to UV
BkAM31D_RS14140	COG2340	Cysteine-rich secretory protein family
BkAM31D_RS14155	COG0628	permease
BkAM31D_RS14165	COG5002	protein histidine kinase activity
BkAM31D_RS14170	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS14180	COG2322	membrane
BkAM31D_RS14185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BkAM31D_RS14190	COG1845	cytochrome c oxidase, subunit III
BkAM31D_RS14195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BkAM31D_RS14200	COG2010	Cytochrome c
BkAM31D_RS14200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BkAM31D_RS14205	COG0109	protoheme IX farnesyltransferase activity
BkAM31D_RS14210	COG1612	heme a metabolic process
BkAM31D_RS14215	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BkAM31D_RS14220	COG4838	Belongs to the UPF0358 family
BkAM31D_RS14225	COG2066	Belongs to the glutaminase family
BkAM31D_RS14230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BkAM31D_RS14235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BkAM31D_RS14245	COG4896	Protein conserved in bacteria
BkAM31D_RS14255	COG1217	gtp-binding protein TYPA
BkAM31D_RS14270	COG0483	inositol monophosphate 1-phosphatase activity
BkAM31D_RS14280	COG4493	Belongs to the UPF0637 family
BkAM31D_RS14285	COG4476	Belongs to the UPF0223 family
BkAM31D_RS14295	COG1982	Orn Lys Arg decarboxylase major
BkAM31D_RS14320	COG4129	membrane
BkAM31D_RS14325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_RS14345	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_RS14350	COG0022	dehydrogenase e1 component
BkAM31D_RS14375	COG5503	Protein of unknown function (DUF1447)
BkAM31D_RS14380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BkAM31D_RS14395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_RS14400	COG0450	alkyl hydroperoxide reductase
BkAM31D_RS14405	COG0668	transmembrane transport
BkAM31D_RS14415	COG1473	amidohydrolase
BkAM31D_RS14420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BkAM31D_RS14425	COG2171	N-acyltransferase activity
BkAM31D_RS14430	COG0679	Auxin Efflux Carrier
BkAM31D_RS14435	COG2224	Isocitrate lyase
BkAM31D_RS14445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_RS14450	COG0668	transmembrane transport
BkAM31D_RS14465	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BkAM31D_RS14475	COG0778	Nitroreductase
BkAM31D_RS14480	COG3192	ethanolamine utilization protein
BkAM31D_RS14495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_RS14500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BkAM31D_RS14505	COG2186	Transcriptional regulator
BkAM31D_RS14510	COG0710	3-dehydroquinate dehydratase activity
BkAM31D_RS14515	COG0028	Belongs to the TPP enzyme family
BkAM31D_RS14525	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS14530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BkAM31D_RS14545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS14545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS14550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS14570	COG2508	Transcriptional regulator
BkAM31D_RS14575	COG3842	ATPase activity
BkAM31D_RS14580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BkAM31D_RS14595	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS14600	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS14610	COG1609	Transcriptional regulator
BkAM31D_RS14615	COG4753	response regulator
BkAM31D_RS14615	COG2207	Transcriptional regulator
BkAM31D_RS14620	COG2972	Histidine kinase
BkAM31D_RS14650	COG0366	Alpha amylase catalytic
BkAM31D_RS14655	COG1609	Transcriptional regulator
BkAM31D_RS14660	COG3833	ABC-type maltose transport systems, permease component
BkAM31D_RS14665	COG1175	transmembrane transport
BkAM31D_RS14670	COG2182	Extracellular solute-binding protein
BkAM31D_RS14675	COG0534	Mate efflux family protein
BkAM31D_RS14680	COG1404	Belongs to the peptidase S8 family
BkAM31D_RS14695	COG2340	Cysteine-rich secretory protein family
BkAM31D_RS14705	COG1525	nuclease
BkAM31D_RS14720	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_RS14725	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_RS14750	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BkAM31D_RS14755	COG0205	6-phosphofructokinase activity
BkAM31D_RS14765	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BkAM31D_RS14770	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BkAM31D_RS14775	COG1691	(AIR) carboxylase
BkAM31D_RS14780	COG1070	Carbohydrate kinase
BkAM31D_RS14785	COG1606	tRNA processing
BkAM31D_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS14800	COG1904	glucuronate isomerase
BkAM31D_RS14810	COG0582	viral genome integration into host DNA
BkAM31D_RS14820	COG5002	protein histidine kinase activity
BkAM31D_RS14825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BkAM31D_RS14830	COG0784	Response regulator, receiver
BkAM31D_RS14830	COG2205	protein histidine kinase activity
BkAM31D_RS14840	COG1082	Xylose isomerase domain protein TIM barrel
BkAM31D_RS14845	COG0523	cobalamin synthesis protein
BkAM31D_RS14850	COG5577	PFAM Coat F domain
BkAM31D_RS14865	COG5577	PFAM Coat F domain
BkAM31D_RS14870	COG1063	alcohol dehydrogenase
BkAM31D_RS14875	COG3773	Cell wall hydrolase
BkAM31D_RS14880	COG5278	phosphoserine phosphatase activity
BkAM31D_RS14880	COG0840	transmembrane signaling receptor activity
BkAM31D_RS14890	COG1082	Xylose isomerase domain protein TIM barrel
BkAM31D_RS14895	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS14900	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS14905	COG1129	ABC transporter
BkAM31D_RS14910	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS14925	COG1609	Transcriptional regulator
BkAM31D_RS14940	COG2205	protein histidine kinase activity
BkAM31D_RS14940	COG0784	Response regulator, receiver
BkAM31D_RS14950	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BkAM31D_RS14955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BkAM31D_RS14960	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BkAM31D_RS14965	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BkAM31D_RS14970	COG0300	oxidoreductase activity
BkAM31D_RS14975	COG0656	L-ascorbic acid biosynthetic process
BkAM31D_RS14990	COG1733	regulation of RNA biosynthetic process
BkAM31D_RS15000	COG0482	sulfurtransferase activity
BkAM31D_RS15005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_RS15030	COG3773	Cell wall hydrolase
BkAM31D_RS15050	COG0183	Belongs to the thiolase family
BkAM31D_RS15055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_RS15060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BkAM31D_RS15075	COG0542	response to heat
BkAM31D_RS15080	COG1253	flavin adenine dinucleotide binding
BkAM31D_RS15090	COG1253	flavin adenine dinucleotide binding
BkAM31D_RS15100	COG5002	protein histidine kinase activity
BkAM31D_RS15120	COG0582	viral genome integration into host DNA
BkAM31D_RS15155	COG4372	Transposase
BkAM31D_RS15180	COG0704	Plays a role in the regulation of phosphate uptake
BkAM31D_RS15190	COG0628	permease
BkAM31D_RS15205	COG1320	monovalent cation:proton antiporter activity
BkAM31D_RS15210	COG2212	antiporter activity
BkAM31D_RS15215	COG1863	multisubunit Na H antiporter MnhE subunit
BkAM31D_RS15220	COG0651	ATP synthesis coupled electron transport
BkAM31D_RS15225	COG1006	Multisubunit Na H antiporter MnhC subunit
BkAM31D_RS15230	COG2111	Na H antiporter
BkAM31D_RS15245	COG3263	regulation of cellular component size
BkAM31D_RS15250	COG0582	viral genome integration into host DNA
BkAM31D_RS15300	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS15305	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_RS15310	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_RS15345	COG0084	hydrolase, TatD family'
BkAM31D_RS15385	COG0508	dehydrogenase complex catalyzes the overall conversion of
BkAM31D_RS15390	COG0022	dehydrogenase e1 component
BkAM31D_RS15395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BkAM31D_RS15400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BkAM31D_RS15425	COG0463	Glycosyl transferase, family 2
BkAM31D_RS15435	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS15440	COG0750	zinc metalloprotease
BkAM31D_RS15445	COG0497	DNA recombination
BkAM31D_RS15450	COG1438	arginine binding
BkAM31D_RS15455	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BkAM31D_RS15460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BkAM31D_RS15475	COG1722	exodeoxyribonuclease VII activity
BkAM31D_RS15480	COG1570	exodeoxyribonuclease VII activity
BkAM31D_RS15485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BkAM31D_RS15490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BkAM31D_RS15495	COG1302	Protein conserved in bacteria
BkAM31D_RS15500	COG0439	Biotin carboxylase
BkAM31D_RS15505	COG0511	ligase activity, forming carbon-carbon bonds
BkAM31D_RS15550	COG3854	ATPases associated with a variety of cellular activities
BkAM31D_RS15560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BkAM31D_RS15565	COG0006	proline dipeptidase activity
BkAM31D_RS15580	COG1752	Esterase of the alpha-beta hydrolase superfamily
BkAM31D_RS15585	COG1321	iron dependent repressor
BkAM31D_RS15590	COG1533	DNA photolyase activity
BkAM31D_RS15595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BkAM31D_RS15610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS15615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BkAM31D_RS15620	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BkAM31D_RS15625	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BkAM31D_RS15630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_RS15645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS15685	COG4537	Required for transformation and DNA binding
BkAM31D_RS15690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BkAM31D_RS15790	COG1459	type II secretion system
BkAM31D_RS15800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BkAM31D_RS15815	COG1403	HNH endonuclease
BkAM31D_RS15825	COG0210	DNA helicase
BkAM31D_RS15830	COG1418	mRNA catabolic process
BkAM31D_RS15855	COG0475	glutathione-regulated potassium exporter activity
BkAM31D_RS15855	COG0589	response to stress
BkAM31D_RS15860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BkAM31D_RS15870	COG0564	pseudouridine synthase activity
BkAM31D_RS15875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BkAM31D_RS15880	COG2357	RelA SpoT domain protein
BkAM31D_RS15895	COG0741	lytic transglycosylase activity
BkAM31D_RS15900	COG2346	COG2346, Truncated hemoglobins
BkAM31D_RS15905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BkAM31D_RS15910	COG1164	Oligoendopeptidase f
BkAM31D_RS15915	COG4469	Competence protein
BkAM31D_RS15920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BkAM31D_RS15925	COG4862	establishment of competence for transformation
BkAM31D_RS15930	COG0861	Integral membrane protein TerC family
BkAM31D_RS15935	COG1393	Belongs to the ArsC family
BkAM31D_RS15940	COG0456	acetyltransferase
BkAM31D_RS15950	COG0166	Belongs to the GPI family
BkAM31D_RS15955	COG1272	protein, Hemolysin III
BkAM31D_RS15960	COG1418	mRNA catabolic process
BkAM31D_RS15980	COG1063	alcohol dehydrogenase
BkAM31D_RS15990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BkAM31D_RS16015	COG5504	Zn-dependent protease
BkAM31D_RS16025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BkAM31D_RS16030	COG1072	(Pantothenic acid kinase))
BkAM31D_RS16035	COG3773	Cell wall hydrolase
BkAM31D_RS16050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BkAM31D_RS16050	COG0617	tRNA 3'-terminal CCA addition
BkAM31D_RS16050	COG3620	sequence-specific DNA binding
BkAM31D_RS16055	COG0427	acetyl-CoA hydrolase
BkAM31D_RS16065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BkAM31D_RS16070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BkAM31D_RS16090	COG1744	ABC transporter substrate-binding protein PnrA-like
BkAM31D_RS16095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BkAM31D_RS16100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BkAM31D_RS16105	COG2267	carboxylic ester hydrolase activity
BkAM31D_RS16115	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BkAM31D_RS16120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BkAM31D_RS16125	COG0505	Belongs to the CarA family
BkAM31D_RS16135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BkAM31D_RS16140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BkAM31D_RS16145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BkAM31D_RS16160	COG1999	signal sequence binding
BkAM31D_RS16165	COG3336	cytochrome c oxidase
BkAM31D_RS16170	COG0561	phosphatase activity
BkAM31D_RS16190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BkAM31D_RS16205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BkAM31D_RS16220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_RS16225	COG1073	alpha beta
BkAM31D_RS16240	COG0425	Belongs to the sulfur carrier protein TusA family
BkAM31D_RS16240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BkAM31D_RS16245	COG0628	permease
BkAM31D_RS16265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_RS16265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_RS16275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BkAM31D_RS16280	COG1309	transcriptional regulator
BkAM31D_RS16295	COG0569	domain protein
BkAM31D_RS16300	COG2201	protein-glutamate methylesterase activity
BkAM31D_RS16305	COG0835	chemotaxis
BkAM31D_RS16310	COG2198	Histidine kinase
BkAM31D_RS16310	COG0643	Histidine kinase
BkAM31D_RS16315	COG5001	Diguanylate cyclase
BkAM31D_RS16315	COG3300	MHYT domain
BkAM31D_RS16320	COG1074	ATP-dependent DNA helicase activity
BkAM31D_RS16325	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BkAM31D_RS16330	COG2153	protein acetylation
BkAM31D_RS16335	COG2368	4-hydroxyphenylacetate
BkAM31D_RS16355	COG0805	protein transport
BkAM31D_RS16360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BkAM31D_RS16375	COG0704	Plays a role in the regulation of phosphate uptake
BkAM31D_RS16380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BkAM31D_RS16385	COG0581	inorganic phosphate transmembrane transporter activity
BkAM31D_RS16390	COG0573	inorganic phosphate transmembrane transporter activity
BkAM31D_RS16395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BkAM31D_RS16410	COG1668	transmembrane transport
BkAM31D_RS16415	COG4152	abc transporter atp-binding protein
BkAM31D_RS16430	COG0697	spore germination
BkAM31D_RS16440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BkAM31D_RS16460	COG0659	secondary active sulfate transmembrane transporter activity
BkAM31D_RS16465	COG0346	lactoylglutathione lyase activity
BkAM31D_RS16485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BkAM31D_RS16490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BkAM31D_RS16495	COG0640	Transcriptional regulator
BkAM31D_RS16500	COG1234	tRNA 3'-trailer cleavage
BkAM31D_RS16505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BkAM31D_RS16510	COG2868	ribosomal protein
BkAM31D_RS16515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BkAM31D_RS16520	COG1530	ribonuclease E activity
BkAM31D_RS16525	COG1994	Peptidase M50
BkAM31D_RS16530	COG0739	heme binding
BkAM31D_RS16535	COG0667	Aldo Keto reductase
BkAM31D_RS16540	COG0521	Mo-molybdopterin cofactor biosynthetic process
BkAM31D_RS16545	COG2894	cell division
BkAM31D_RS16550	COG0850	regulation of cytokinetic process
BkAM31D_RS16565	COG1077	Cell shape determining protein MreB Mrl
BkAM31D_RS16570	COG2003	Belongs to the UPF0758 family
BkAM31D_RS16575	COG0424	maF-like protein
BkAM31D_RS16585	COG1459	type II secretion system
BkAM31D_RS16595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BkAM31D_RS16635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BkAM31D_RS16645	COG0285	dihydrofolate synthase activity
BkAM31D_RS16660	COG1595	DNA-templated transcription, initiation
BkAM31D_RS16665	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BkAM31D_RS16690	COG1388	LysM domain
BkAM31D_RS16695	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BkAM31D_RS16700	COG0113	porphobilinogen synthase activity
BkAM31D_RS16705	COG1587	Uroporphyrinogen-III synthase
BkAM31D_RS16710	COG0181	hydroxymethylbilane synthase activity
BkAM31D_RS16720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BkAM31D_RS16730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BkAM31D_RS16740	COG0470	DNA polymerase III
BkAM31D_RS16740	COG1067	ATP-dependent peptidase activity
BkAM31D_RS16745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BkAM31D_RS16750	COG0544	peptidyl-prolyl cis-trans isomerase activity
BkAM31D_RS16755	COG1477	protein flavinylation
BkAM31D_RS16755	COG0457	Tetratricopeptide repeat
BkAM31D_RS16760	COG0066	3-isopropylmalate dehydratase activity
BkAM31D_RS16765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BkAM31D_RS16770	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_RS16775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_RS16780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BkAM31D_RS16785	COG0440	acetolactate synthase activity
BkAM31D_RS16790	COG0028	Belongs to the TPP enzyme family
BkAM31D_RS16795	COG0129	dihydroxy-acid dehydratase activity
BkAM31D_RS16800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BkAM31D_RS16825	COG0622	Phosphoesterase
BkAM31D_RS16830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BkAM31D_RS16835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BkAM31D_RS16840	COG5401	PFAM Sporulation and spore germination
BkAM31D_RS16850	COG1846	Transcriptional regulator
BkAM31D_RS16855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BkAM31D_RS16860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BkAM31D_RS16865	COG2197	response regulator
BkAM31D_RS16875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BkAM31D_RS16880	COG1053	succinate dehydrogenase
BkAM31D_RS16885	COG2009	succinate dehydrogenase
BkAM31D_RS16890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BkAM31D_RS16895	COG1719	4-vinyl reductase, 4VR
BkAM31D_RS16905	COG0322	excinuclease ABC activity
BkAM31D_RS16910	COG3118	belongs to the thioredoxin family
BkAM31D_RS16915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_RS16920	COG2086	electron transfer activity
BkAM31D_RS16925	COG1024	Enoyl-CoA hydratase
BkAM31D_RS16930	COG1309	transcriptional regulator
BkAM31D_RS16935	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_RS16945	COG0318	PFAM AMP-dependent synthetase and ligase
BkAM31D_RS16950	COG3766	membrane
BkAM31D_RS16955	COG1193	negative regulation of DNA recombination
BkAM31D_RS16965	COG1286	toxin biosynthetic process
BkAM31D_RS16970	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BkAM31D_RS16975	COG0072	phenylalanine-tRNA ligase activity
BkAM31D_RS16975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BkAM31D_RS16980	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BkAM31D_RS16985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BkAM31D_RS16995	COG1363	Peptidase, m42
BkAM31D_RS17020	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BkAM31D_RS17025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BkAM31D_RS17030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BkAM31D_RS17045	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BkAM31D_RS17050	COG1484	DNA-dependent DNA replication
BkAM31D_RS17055	COG3611	Membrane attachment protein
BkAM31D_RS17060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BkAM31D_RS17065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BkAM31D_RS17070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BkAM31D_RS17075	COG0237	dephospho-CoA kinase activity
BkAM31D_RS17080	COG1971	Probably functions as a manganese efflux pump
BkAM31D_RS17095	COG0330	HflC and HflK could
BkAM31D_RS17100	COG0330	HflC and HflK could
BkAM31D_RS17105	COG5002	protein histidine kinase activity
BkAM31D_RS17110	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS17115	COG0039	L-malate dehydrogenase activity
BkAM31D_RS17120	COG0538	isocitrate dehydrogenase activity
BkAM31D_RS17125	COG0372	Belongs to the citrate synthase family
BkAM31D_RS17130	COG2707	UPF0756 membrane protein
BkAM31D_RS17135	COG3030	protein affecting phage T7 exclusion by the F plasmid
BkAM31D_RS17145	COG0205	6-phosphofructokinase activity
BkAM31D_RS17160	COG2186	Transcriptional regulator
BkAM31D_RS17165	COG0281	malic enzyme
BkAM31D_RS17170	COG0587	DNA-directed DNA polymerase activity
BkAM31D_RS17190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BkAM31D_RS17210	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BkAM31D_RS17215	COG0006	proline dipeptidase activity
BkAM31D_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS17230	COG0165	Argininosuccinate lyase
BkAM31D_RS17235	COG0137	argininosuccinate synthase activity
BkAM31D_RS17245	COG2217	Heavy metal translocating P-type atpase
BkAM31D_RS17250	COG3481	metal-dependent phosphohydrolase, HD sub domain
BkAM31D_RS17255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BkAM31D_RS17265	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BkAM31D_RS17280	COG1714	RDD family
BkAM31D_RS17285	COG0616	signal peptide processing
BkAM31D_RS17290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BkAM31D_RS17305	COG0301	tRNA thio-modification
BkAM31D_RS17310	COG1104	cysteine desulfurase activity
BkAM31D_RS17315	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BkAM31D_RS17320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BkAM31D_RS17325	COG1309	transcriptional regulator
BkAM31D_RS17330	COG1956	GAF domain-containing protein
BkAM31D_RS17335	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BkAM31D_RS17340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BkAM31D_RS17350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BkAM31D_RS17355	COG0454	-acetyltransferase
BkAM31D_RS17360	COG0517	IMP dehydrogenase activity
BkAM31D_RS17365	COG0123	including yeast histone deacetylase and acetoin utilization protein
BkAM31D_RS17370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BkAM31D_RS17380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BkAM31D_RS17390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BkAM31D_RS17390	COG1605	Chorismate mutase
BkAM31D_RS17395	COG4980	gas vesicle protein
BkAM31D_RS17405	COG2309	aminopeptidase activity
BkAM31D_RS17410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BkAM31D_RS17420	COG1674	ftsk spoiiie
BkAM31D_RS17425	COG4848	Belongs to the UPF0354 family
BkAM31D_RS17430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BkAM31D_RS17450	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BkAM31D_RS17455	COG1363	Peptidase, m42
BkAM31D_RS17465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS17470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BkAM31D_RS17480	COG0510	thiamine kinase activity
BkAM31D_RS17485	COG1523	belongs to the glycosyl hydrolase 13 family
BkAM31D_RS17490	COG0788	formyltetrahydrofolate deformylase activity
BkAM31D_RS17505	COG1346	cytolysis
BkAM31D_RS17510	COG1380	Effector of murein hydrolase LrgA
BkAM31D_RS17520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BkAM31D_RS17525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BkAM31D_RS17530	COG1349	DNA-binding transcription factor activity
BkAM31D_RS17535	COG1187	pseudouridine synthase activity
BkAM31D_RS17545	COG0772	Belongs to the SEDS family
BkAM31D_RS17550	COG0772	Belongs to the SEDS family
BkAM31D_RS17560	COG2081	HI0933 family
BkAM31D_RS17570	COG0495	leucyl-tRNA aminoacylation
BkAM31D_RS17575	COG2814	Major facilitator Superfamily
BkAM31D_RS17580	COG1242	4 iron, 4 sulfur cluster binding
BkAM31D_RS17585	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BkAM31D_RS17590	COG0288	reversible hydration of carbon dioxide
BkAM31D_RS17600	COG2267	carboxylic ester hydrolase activity
BkAM31D_RS17605	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BkAM31D_RS17625	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BkAM31D_RS17640	COG2267	carboxylic ester hydrolase activity
BkAM31D_RS17645	COG1506	peptidase
BkAM31D_RS17650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BkAM31D_RS17655	COG1116	anion transmembrane transporter activity
BkAM31D_RS17660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_RS17665	COG0494	nUDIX hydrolase
BkAM31D_RS17670	COG2814	Major facilitator Superfamily
BkAM31D_RS17685	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BkAM31D_RS17690	COG0488	(ABC) transporter
BkAM31D_RS17695	COG1428	Deoxynucleoside kinase
BkAM31D_RS17700	COG1428	Deoxynucleoside kinase
BkAM31D_RS17725	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS17730	COG2706	6-phosphogluconolactonase activity
BkAM31D_RS17740	COG2814	Major facilitator Superfamily
BkAM31D_RS17745	COG0473	3-isopropylmalate dehydrogenase activity
BkAM31D_RS17750	COG0471	metal ion transport
BkAM31D_RS17760	COG4565	transcriptional regulatory protein
BkAM31D_RS17765	COG3290	protein histidine kinase activity
BkAM31D_RS17775	COG0561	phosphatase activity
BkAM31D_RS17805	COG1785	Belongs to the alkaline phosphatase family
BkAM31D_RS17830	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BkAM31D_RS17835	COG0506	proline dehydrogenase activity
BkAM31D_RS17840	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS17850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BkAM31D_RS17855	COG3829	transcription factor binding
BkAM31D_RS17860	COG1288	antiporter activity
BkAM31D_RS17870	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BkAM31D_RS17875	COG3829	transcription factor binding
BkAM31D_RS17880	COG3829	transcription factor binding
BkAM31D_RS17975	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS18040	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_RS18050	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS18055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BkAM31D_RS18070	COG1979	alcohol dehydrogenase
BkAM31D_RS18075	COG2155	Conserved Protein
BkAM31D_RS18080	COG1098	S1 RNA binding domain
BkAM31D_RS18090	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BkAM31D_RS18095	COG0436	Aminotransferase
BkAM31D_RS18100	COG1522	sequence-specific DNA binding
BkAM31D_RS18105	COG1335	isochorismatase
BkAM31D_RS18115	COG1295	ribonuclease BN
BkAM31D_RS18120	COG0776	regulation of translation
BkAM31D_RS18125	COG1714	RDD family
BkAM31D_RS18130	COG1268	BioY protein
BkAM31D_RS18135	COG2056	Na+-H+ antiporter family
BkAM31D_RS18140	COG1131	(ABC) transporter
BkAM31D_RS18145	COG1725	Transcriptional regulator
BkAM31D_RS18155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS18160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS18165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS18170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BkAM31D_RS18175	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BkAM31D_RS18185	COG3584	3D domain protein
BkAM31D_RS18195	COG1252	NADH dehydrogenase
BkAM31D_RS18200	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_RS18205	COG0316	Belongs to the HesB IscA family
BkAM31D_RS18215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BkAM31D_RS18225	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BkAM31D_RS18235	COG4844	belongs to the
BkAM31D_RS18240	COG1252	NADH dehydrogenase
BkAM31D_RS18255	COG4837	Protein of unknown function (DUF1462)
BkAM31D_RS18260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BkAM31D_RS18270	COG0083	homoserine kinase activity
BkAM31D_RS18275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BkAM31D_RS18280	COG0460	homoserine dehydrogenase
BkAM31D_RS18285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BkAM31D_RS18290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BkAM31D_RS18295	COG5002	protein histidine kinase activity
BkAM31D_RS18300	COG0647	UMP catabolic process
BkAM31D_RS18310	COG2445	Protein of unknown function DUF86
BkAM31D_RS18325	COG4470	Protein conserved in bacteria
BkAM31D_RS18335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BkAM31D_RS18340	COG0739	heme binding
BkAM31D_RS18375	COG1757	Na H antiporter
BkAM31D_RS18385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BkAM31D_RS18390	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BkAM31D_RS18395	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BkAM31D_RS18400	COG1902	pentaerythritol trinitrate reductase activity
BkAM31D_RS18415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BkAM31D_RS18435	COG4191	Histidine kinase
BkAM31D_RS18450	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BkAM31D_RS18465	COG2358	TRAP transporter, solute receptor (TAXI family
BkAM31D_RS18475	COG3377	Domain of unknown function (DUF1805)
BkAM31D_RS18480	COG0737	Belongs to the 5'-nucleotidase family
BkAM31D_RS18485	COG0730	response to heat
BkAM31D_RS18490	COG1801	Protein of unknown function DUF72
BkAM31D_RS18495	COG0719	Fe-S assembly protein
BkAM31D_RS18500	COG0822	iron-sulfur transferase activity
BkAM31D_RS18505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BkAM31D_RS18510	COG0719	Fe-S assembly protein
BkAM31D_RS18515	COG0396	ATPase activity
BkAM31D_RS18520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BkAM31D_RS18525	COG1464	Belongs to the NlpA lipoprotein family
BkAM31D_RS18530	COG2011	ABC-type metal ion transport system permease component
BkAM31D_RS18535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BkAM31D_RS18545	COG0509	glycine decarboxylation via glycine cleavage system
BkAM31D_RS18550	COG1393	Belongs to the ArsC family
BkAM31D_RS18555	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS18560	COG0183	Belongs to the thiolase family
BkAM31D_RS18565	COG1024	Enoyl-CoA hydratase
BkAM31D_RS18565	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS18575	COG5577	PFAM Coat F domain
BkAM31D_RS18640	COG1192	Involved in chromosome partitioning
BkAM31D_RS18680	COG5002	protein histidine kinase activity
BkAM31D_RS18700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BkAM31D_RS18710	COG0557	exoribonuclease II activity
BkAM31D_RS18715	COG1647	Serine aminopeptidase, S33
BkAM31D_RS18740	COG0789	Transcriptional regulator
BkAM31D_RS18745	COG0655	NAD(P)H dehydrogenase (quinone) activity
BkAM31D_RS18750	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_RS18755	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_RS18780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BkAM31D_RS18790	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BkAM31D_RS18805	COG0148	phosphopyruvate hydratase activity
BkAM31D_RS18810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BkAM31D_RS18815	COG0149	triose-phosphate isomerase activity
BkAM31D_RS18825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BkAM31D_RS18840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BkAM31D_RS18845	COG0740	serine-type endopeptidase activity
BkAM31D_RS18850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BkAM31D_RS18855	COG1481	regulation of sporulation
BkAM31D_RS18860	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BkAM31D_RS18865	COG1660	Displays ATPase and GTPase activities
BkAM31D_RS18870	COG1051	belongs to the nudix hydrolase family
BkAM31D_RS18875	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_RS18880	COG0457	Tetratricopeptide repeat
BkAM31D_RS18885	COG0140	phosphoribosyl-ATP diphosphatase activity
BkAM31D_RS18885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BkAM31D_RS18890	COG0107	imidazoleglycerol-phosphate synthase activity
BkAM31D_RS18895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BkAM31D_RS18900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BkAM31D_RS18905	COG0131	Imidazoleglycerol-phosphate dehydratase
BkAM31D_RS18910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BkAM31D_RS18915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BkAM31D_RS18920	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BkAM31D_RS18925	COG0110	maltose O-acetyltransferase activity
BkAM31D_RS18930	COG0546	phosphoglycolate phosphatase activity
BkAM31D_RS18935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BkAM31D_RS18945	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BkAM31D_RS18950	COG1950	PFAM Membrane protein of
BkAM31D_RS18955	COG1983	PspC domain protein
BkAM31D_RS18960	COG3595	metallopeptidase activity
BkAM31D_RS18970	COG0556	nucleotide-excision repair
BkAM31D_RS18980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BkAM31D_RS18985	COG0793	Belongs to the peptidase S41A family
BkAM31D_RS18985	COG3409	Peptidoglycan-binding domain 1 protein
BkAM31D_RS18990	COG0739	heme binding
BkAM31D_RS18995	COG2177	Part of the ABC transporter FtsEX involved in
BkAM31D_RS19000	COG2884	Cell division ATP-binding protein ftsE
BkAM31D_RS19010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BkAM31D_RS19020	COG0653	protein targeting
BkAM31D_RS19035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BkAM31D_RS19045	COG1278	Cold shock
BkAM31D_RS19065	COG1516	flagellar protein fliS
BkAM31D_RS19070	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BkAM31D_RS19075	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BkAM31D_RS19090	COG0667	Aldo Keto reductase
BkAM31D_RS19095	COG1070	Carbohydrate kinase
BkAM31D_RS19100	COG2115	Belongs to the xylose isomerase family
BkAM31D_RS19105	COG5578	integral membrane protein
BkAM31D_RS19115	COG1175	transmembrane transport
BkAM31D_RS19125	COG1940	carbohydrate kinase activity
BkAM31D_RS19130	COG3507	Belongs to the glycosyl hydrolase 43 family
BkAM31D_RS19135	COG3693	PFAM glycoside hydrolase, family 10
BkAM31D_RS19145	COG0189	ligase activity
BkAM31D_RS19155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BkAM31D_RS19160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BkAM31D_RS19165	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BkAM31D_RS19175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BkAM31D_RS19180	COG4786	Flagellar basal body rod
BkAM31D_RS19180	COG1256	bacterial-type flagellum assembly
BkAM31D_RS19200	COG1040	competence protein
BkAM31D_RS19205	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BkAM31D_RS19270	COG4974	Belongs to the 'phage' integrase family
BkAM31D_RS19275	COG3655	Transcriptional regulator
BkAM31D_RS19405	COG0629	single-stranded DNA binding
BkAM31D_RS19410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BkAM31D_RS19475	COG3935	DnaD domain protein
BkAM31D_RS19485	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BkAM31D_RS19500	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BkAM31D_RS19515	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS19550	COG1396	sequence-specific DNA binding
BkAM31D_RS19570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BkAM31D_RS19575	COG1307	EDD domain protein, DegV family
BkAM31D_RS19590	COG1739	Uncharacterized protein family UPF0029
BkAM31D_RS19600	COG0432	Pfam Uncharacterised protein family UPF0047
BkAM31D_RS19605	COG1705	Flagellar rod assembly protein muramidase FlgJ
BkAM31D_RS19605	COG1388	LysM domain
BkAM31D_RS19610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BkAM31D_RS19615	COG0601	transmembrane transport
BkAM31D_RS19625	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_RS19635	COG1316	TRANSCRIPTIONal
BkAM31D_RS19640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BkAM31D_RS19645	COG4193	domain, Protein
BkAM31D_RS19655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_RS19660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BkAM31D_RS19665	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BkAM31D_RS19670	COG1404	Belongs to the peptidase S8 family
BkAM31D_RS19675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BkAM31D_RS19690	COG1181	Belongs to the D-alanine--D-alanine ligase family
BkAM31D_RS19690	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BkAM31D_RS19700	COG1216	Glycosyl transferase, family 2
BkAM31D_RS19700	COG1442	glycosyl transferase family 8
BkAM31D_RS19715	COG1215	transferase activity, transferring glycosyl groups
BkAM31D_RS19725	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_RS19740	COG1115	amino acid carrier protein
BkAM31D_RS19745	COG0189	ligase activity
BkAM31D_RS19745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BkAM31D_RS19755	COG1316	TRANSCRIPTIONal
BkAM31D_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS19775	COG2203	Gaf domain
BkAM31D_RS19775	COG2199	diguanylate cyclase activity
BkAM31D_RS19785	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BkAM31D_RS19790	COG3842	ATPase activity
BkAM31D_RS19800	COG1176	ABC-type spermidine putrescine transport system, permease component I
BkAM31D_RS19825	COG3173	Aminoglycoside phosphotransferase
BkAM31D_RS19830	COG0405	Gamma-glutamyltransferase
BkAM31D_RS19835	COG1301	dicarboxylic acid transport
BkAM31D_RS19845	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BkAM31D_RS19850	COG0697	spore germination
BkAM31D_RS19865	COG1609	Transcriptional regulator
BkAM31D_RS19870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_RS19880	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS19885	COG4638	Rieske (2fe-2S)
BkAM31D_RS19890	COG1141	Ferredoxin
BkAM31D_RS19895	COG0492	ferredoxin-NADP+ reductase activity
BkAM31D_RS19900	COG3829	transcription factor binding
BkAM31D_RS19910	COG1525	nuclease
BkAM31D_RS19910	COG4085	toxin activity
BkAM31D_RS19910	COG0737	Belongs to the 5'-nucleotidase family
BkAM31D_RS19925	COG4607	ABC-type enterochelin transport system periplasmic component
BkAM31D_RS19935	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_RS19965	COG0583	DNA-binding transcription factor activity
BkAM31D_RS19970	COG0110	maltose O-acetyltransferase activity
BkAM31D_RS19975	COG0038	chloride channel
BkAM31D_RS20000	COG1757	Na H antiporter
BkAM31D_RS20005	COG1473	amidohydrolase
BkAM31D_RS20040	COG0506	proline dehydrogenase activity
BkAM31D_RS20055	COG0583	DNA-binding transcription factor activity
BkAM31D_RS20065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_RS20070	COG0405	Gamma-glutamyltransferase
BkAM31D_RS20080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BkAM31D_RS20125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS20135	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS20135	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BkAM31D_RS20140	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS20145	COG0697	spore germination
BkAM31D_RS20165	COG0814	amino acid
BkAM31D_RS20175	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BkAM31D_RS20190	COG2755	lipolytic protein G-D-S-L family
BkAM31D_RS20210	COG2814	Major facilitator Superfamily
BkAM31D_RS20240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BkAM31D_RS20260	COG1929	Belongs to the glycerate kinase type-1 family
BkAM31D_RS20265	COG2610	gluconate transmembrane transporter activity
BkAM31D_RS20270	COG3835	regulator
BkAM31D_RS20290	COG0346	lactoylglutathione lyase activity
BkAM31D_RS20300	COG4187	Peptidase family M20/M25/M40
BkAM31D_RS20320	COG1288	antiporter activity
BkAM31D_RS20340	COG0583	DNA-binding transcription factor activity
BkAM31D_RS20345	COG0010	Belongs to the arginase family
BkAM31D_RS20350	COG0786	glutamate:sodium symporter activity
BkAM31D_RS20370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS20390	COG1595	DNA-templated transcription, initiation
BkAM31D_RS20405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BkAM31D_RS20405	COG0456	acetyltransferase
BkAM31D_RS20460	COG0753	catalase activity
BkAM31D_RS20470	COG1595	DNA-templated transcription, initiation
BkAM31D_RS20485	COG1695	Transcriptional regulator
BkAM31D_RS20495	COG2364	Membrane
BkAM31D_RS20510	COG0667	Aldo Keto reductase
BkAM31D_RS20520	COG0577	efflux transmembrane transporter activity
BkAM31D_RS20525	COG1136	(ABC) transporter
BkAM31D_RS20530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BkAM31D_RS20535	COG4152	abc transporter atp-binding protein
BkAM31D_RS20560	COG2197	response regulator
BkAM31D_RS20585	COG2113	Glycine betaine
BkAM31D_RS20590	COG4176	ABC-type proline glycine betaine transport system permease component
BkAM31D_RS20595	COG4175	Glycine betaine
BkAM31D_RS20595	COG0517	IMP dehydrogenase activity
BkAM31D_RS20600	COG1510	regulation of RNA biosynthetic process
BkAM31D_RS20620	COG0363	glucosamine-6-phosphate deaminase activity
BkAM31D_RS20625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_RS20635	COG4821	SIS domain
BkAM31D_RS20640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BkAM31D_RS20650	COG0673	inositol 2-dehydrogenase activity
BkAM31D_RS20655	COG0395	ABC-type sugar transport system, permease component
BkAM31D_RS20675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BkAM31D_RS20685	COG2188	Transcriptional regulator
BkAM31D_RS20690	COG1126	abc transporter atp-binding protein
BkAM31D_RS20695	COG0765	amino acid transport
BkAM31D_RS20725	COG2268	Band 7 protein
BkAM31D_RS20735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BkAM31D_RS20750	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BkAM31D_RS20755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BkAM31D_RS20770	COG1063	alcohol dehydrogenase
BkAM31D_RS20775	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS20800	COG0583	DNA-binding transcription factor activity
BkAM31D_RS20850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BkAM31D_RS20865	COG1216	Glycosyl transferase, family 2
BkAM31D_RS20870	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_RS20885	COG0438	transferase activity, transferring glycosyl groups
BkAM31D_RS20890	COG1045	serine acetyltransferase
BkAM31D_RS20895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BkAM31D_RS20900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BkAM31D_RS20910	COG1086	Polysaccharide biosynthesis protein
BkAM31D_RS20915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BkAM31D_RS20920	COG4464	protein tyrosine phosphatase activity
BkAM31D_RS20925	COG0489	protein tyrosine kinase activity
BkAM31D_RS20930	COG3944	biosynthesis protein
BkAM31D_RS20935	COG1316	TRANSCRIPTIONal
BkAM31D_RS20980	COG0791	NLP P60 protein
BkAM31D_RS20980	COG1388	LysM domain
BkAM31D_RS20995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_RS20995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BkAM31D_RS21000	COG1349	DNA-binding transcription factor activity
BkAM31D_RS21005	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS21010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BkAM31D_RS21015	COG1494	fructose-1,6-bisphosphatase
BkAM31D_RS21020	COG1461	Dihydroxyacetone kinase
BkAM31D_RS21025	COG2376	Dihydroxyacetone kinase
BkAM31D_RS21030	COG0698	ribose 5-phosphate isomerase
BkAM31D_RS21035	COG2814	Major facilitator Superfamily
BkAM31D_RS21040	COG1063	alcohol dehydrogenase
BkAM31D_RS21050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BkAM31D_RS21090	COG2271	Major facilitator Superfamily
BkAM31D_RS21095	COG1785	Belongs to the alkaline phosphatase family
BkAM31D_RS21100	COG0662	Cupin 2, conserved barrel domain protein
BkAM31D_RS21105	COG1280	lysine exporter protein (LysE YggA)
BkAM31D_RS21115	COG0789	Transcriptional regulator
BkAM31D_RS21135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BkAM31D_RS21140	COG2814	Major facilitator Superfamily
BkAM31D_RS21180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BkAM31D_RS21220	COG0725	ABC transporter, periplasmic molybdate-binding protein
BkAM31D_RS21225	COG4149	molybdate abc transporter
BkAM31D_RS21235	COG1910	domain protein
BkAM31D_RS21240	COG3708	Transcriptional regulator
BkAM31D_RS21240	COG2207	Transcriptional regulator
BkAM31D_RS21245	COG0596	Alpha beta hydrolase
BkAM31D_RS21255	COG3773	Cell wall hydrolase
BkAM31D_RS21265	COG1181	Belongs to the D-alanine--D-alanine ligase family
BkAM31D_RS21265	COG2918	glutathione biosynthetic process
BkAM31D_RS21270	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BkAM31D_RS21280	COG1733	regulation of RNA biosynthetic process
BkAM31D_RS21290	COG5001	Diguanylate cyclase
BkAM31D_RS21325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BkAM31D_RS21350	COG4372	Transposase
BkAM31D_RS21355	COG2207	Transcriptional regulator
BkAM31D_RS21355	COG3708	Transcriptional regulator
BkAM31D_RS21360	COG0640	Transcriptional regulator
BkAM31D_RS21420	COG4640	response to antibiotic
BkAM31D_RS21435	COG2323	membrane
BkAM31D_RS21440	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS21445	COG2610	gluconate transmembrane transporter activity
BkAM31D_RS21455	COG3246	L-lysine catabolic process to acetate
BkAM31D_RS21465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BkAM31D_RS21470	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BkAM31D_RS21475	COG0583	DNA-binding transcription factor activity
BkAM31D_RS21495	COG1414	Transcriptional regulator
BkAM31D_RS21510	COG0697	spore germination
BkAM31D_RS21515	COG1917	Cupin 2, conserved barrel domain protein
BkAM31D_RS21515	COG2207	Transcriptional regulator
BkAM31D_RS21520	COG5646	InterPro IPR014922
BkAM31D_RS21525	COG2079	MmgE PrpD family protein
BkAM31D_RS21530	COG1024	Enoyl-CoA hydratase
BkAM31D_RS21535	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS21540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BkAM31D_RS21545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BkAM31D_RS21550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BkAM31D_RS21560	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS21590	COG0247	lactate metabolic process
BkAM31D_RS21590	COG2181	nitrate reductase activity
BkAM31D_RS21595	COG0583	DNA-binding transcription factor activity
BkAM31D_RS21600	COG2814	Major facilitator Superfamily
BkAM31D_RS21605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BkAM31D_RS21610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BkAM31D_RS21635	COG3655	Transcriptional regulator
BkAM31D_RS21650	COG1879	ABC-type sugar transport system periplasmic component
BkAM31D_RS21655	COG1172	Belongs to the binding-protein-dependent transport system permease family
BkAM31D_RS21660	COG1129	ABC transporter
BkAM31D_RS21665	COG1869	D-ribose catabolic process
BkAM31D_RS21670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BkAM31D_RS21675	COG1609	Transcriptional regulator
BkAM31D_RS21705	COG0640	Transcriptional regulator
BkAM31D_RS21710	COG4191	Histidine kinase
BkAM31D_RS21830	COG0697	spore germination
BkAM31D_RS21855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BkAM31D_RS21895	COG4608	Belongs to the ABC transporter superfamily
BkAM31D_RS21900	COG0444	Belongs to the ABC transporter superfamily
BkAM31D_RS21910	COG0601	transmembrane transport
BkAM31D_RS21935	COG1595	DNA-templated transcription, initiation
BkAM31D_RS21950	COG0662	Cupin 2, conserved barrel domain protein
BkAM31D_RS21975	COG1012	belongs to the aldehyde dehydrogenase family
BkAM31D_RS21980	COG0180	Tryptophanyl-tRNA synthetase
BkAM31D_RS21985	COG1253	flavin adenine dinucleotide binding
BkAM31D_RS21995	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS22000	COG0642	Histidine kinase
BkAM31D_RS22005	COG1136	(ABC) transporter
BkAM31D_RS22010	COG0577	efflux transmembrane transporter activity
BkAM31D_RS22015	COG0402	S-adenosylhomocysteine deaminase activity
BkAM31D_RS22030	COG2843	Capsule synthesis protein
BkAM31D_RS22060	COG1309	transcriptional regulator
BkAM31D_RS22065	COG5002	protein histidine kinase activity
BkAM31D_RS22070	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS22080	COG1388	LysM domain
BkAM31D_RS22140	COG3764	Sortase (surface protein transpeptidase)
BkAM31D_RS22150	COG4191	Histidine kinase
BkAM31D_RS22180	COG0840	transmembrane signaling receptor activity
BkAM31D_RS22320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BkAM31D_RS22330	COG4786	Flagellar basal body rod
BkAM31D_RS22335	COG4786	Flagellar basal body rod
BkAM31D_RS22340	COG1077	Cell shape determining protein MreB Mrl
BkAM31D_RS22345	COG1609	Transcriptional regulator
BkAM31D_RS22360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BkAM31D_RS22375	COG0739	heme binding
BkAM31D_RS22380	COG2385	sporulation resulting in formation of a cellular spore
BkAM31D_RS22390	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BkAM31D_RS22400	COG4836	Membrane
BkAM31D_RS22405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BkAM31D_RS22410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BkAM31D_RS22415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BkAM31D_RS22420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BkAM31D_RS22425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BkAM31D_RS22430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BkAM31D_RS22440	COG0356	it plays a direct role in the translocation of protons across the membrane
BkAM31D_RS22460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BkAM31D_RS22465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BkAM31D_RS22470	COG4475	Protein of unknown function (DUF436)
BkAM31D_RS22475	COG0698	ribose 5-phosphate isomerase
BkAM31D_RS22480	COG0840	transmembrane signaling receptor activity
BkAM31D_RS22485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BkAM31D_RS22490	COG1971	Probably functions as a manganese efflux pump
BkAM31D_RS22495	COG0009	L-threonylcarbamoyladenylate synthase
BkAM31D_RS22515	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BkAM31D_RS22540	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BkAM31D_RS22545	COG1846	Transcriptional regulator
BkAM31D_RS22555	COG1129	ABC transporter
BkAM31D_RS22575	COG0831	urea catabolic process
BkAM31D_RS22585	COG0804	urea catabolic process
BkAM31D_RS22590	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BkAM31D_RS22600	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BkAM31D_RS22610	COG1435	thymidine kinase activity
BkAM31D_RS22615	COG0254	rRNA binding
BkAM31D_RS22620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BkAM31D_RS22625	COG1494	fructose-1,6-bisphosphatase
BkAM31D_RS22630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BkAM31D_RS22635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BkAM31D_RS22640	COG0191	fructose-bisphosphate aldolase activity
BkAM31D_RS22645	COG2204	response regulator
BkAM31D_RS22655	COG0504	CTP synthase activity
BkAM31D_RS22660	COG3343	RNA polymerase activity
BkAM31D_RS22665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_RS22665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BkAM31D_RS22665	COG1703	isobutyryl-CoA mutase activity
BkAM31D_RS22675	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS22680	COG1960	acyl-CoA dehydrogenase activity
BkAM31D_RS22685	COG1250	3-hydroxyacyl-CoA dehydrogenase
BkAM31D_RS22690	COG0183	Belongs to the thiolase family
BkAM31D_RS22695	COG0247	lactate metabolic process
BkAM31D_RS22695	COG2181	nitrate reductase activity
BkAM31D_RS22700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BkAM31D_RS22705	COG2267	carboxylic ester hydrolase activity
BkAM31D_RS22715	COG2839	Protein conserved in bacteria
BkAM31D_RS22720	COG0018	arginyl-trna synthetase
BkAM31D_RS22730	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BkAM31D_RS22735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BkAM31D_RS22745	COG3465	dGTPase activity
BkAM31D_RS22750	COG1078	dGTPase activity
BkAM31D_RS22755	COG4844	belongs to the
BkAM31D_RS22760	COG0095	Lipoate-protein ligase
BkAM31D_RS22765	COG0280	phosphate acetyltransferase
BkAM31D_RS22770	COG1024	Enoyl-CoA hydratase
BkAM31D_RS22775	COG3253	May function as heme-dependent peroxidase
BkAM31D_RS22780	COG3773	Cell wall hydrolase
BkAM31D_RS22790	COG2363	Small membrane protein
BkAM31D_RS22800	COG0789	Transcriptional regulator
BkAM31D_RS22815	COG0004	ammonium transporteR
BkAM31D_RS22825	COG1263	PTS System
BkAM31D_RS22825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BkAM31D_RS22830	COG2207	Transcriptional regulator
BkAM31D_RS22840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BkAM31D_RS22855	COG0513	Belongs to the DEAD box helicase family
BkAM31D_RS22860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BkAM31D_RS22860	COG0723	plastoquinol--plastocyanin reductase activity
BkAM31D_RS22865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BkAM31D_RS22870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BkAM31D_RS22870	COG0551	DNA topoisomerase type I activity
BkAM31D_RS22875	COG2076	Multidrug Resistance protein
BkAM31D_RS22880	COG2076	Multidrug Resistance protein
BkAM31D_RS22885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BkAM31D_RS22890	COG1028	Short-chain dehydrogenase reductase Sdr
BkAM31D_RS22895	COG2814	Major facilitator Superfamily
BkAM31D_RS22910	COG2094	Belongs to the DNA glycosylase MPG family
BkAM31D_RS22925	COG1376	ErfK ybiS ycfS ynhG family protein
BkAM31D_RS22935	COG5582	Belongs to the UPF0302 family
BkAM31D_RS22945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BkAM31D_RS22970	COG2205	protein histidine kinase activity
BkAM31D_RS22980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BkAM31D_RS22990	COG2072	flavoprotein involved in K transport
BkAM31D_RS22995	COG1114	Component of the transport system for branched-chain amino acids
BkAM31D_RS23000	COG2323	membrane
BkAM31D_RS23015	COG0686	Belongs to the AlaDH PNT family
BkAM31D_RS23020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BkAM31D_RS23045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BkAM31D_RS23050	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BkAM31D_RS23055	COG0579	oxidoreductase
BkAM31D_RS23065	COG0583	DNA-binding transcription factor activity
BkAM31D_RS23080	COG3314	Sporulation integral membrane protein YlbJ
BkAM31D_RS23085	COG2226	methyltransferase
BkAM31D_RS23090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BkAM31D_RS23110	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_RS23115	COG1120	ATPase activity
BkAM31D_RS23125	COG1187	pseudouridine synthase activity
BkAM31D_RS23135	COG2329	Antibiotic biosynthesis monooxygenase
BkAM31D_RS23140	COG1120	ATPase activity
BkAM31D_RS23145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BkAM31D_RS23155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BkAM31D_RS23170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BkAM31D_RS23175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BkAM31D_RS23185	COG4863	YycH protein
BkAM31D_RS23190	COG5002	protein histidine kinase activity
BkAM31D_RS23195	COG0745	RESPONSE REGULATOR receiver
BkAM31D_RS23200	COG0739	heme binding
BkAM31D_RS23200	COG0741	lytic transglycosylase activity
BkAM31D_RS23200	COG1196	nuclear chromosome segregation
BkAM31D_RS23230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BkAM31D_RS23235	COG0305	Participates in initiation and elongation during chromosome replication
BkAM31D_RS23240	COG0359	binds to the 23S rRNA
BkAM31D_RS23245	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BkAM31D_RS23250	COG4241	membrane
BkAM31D_RS23255	COG2610	gluconate transmembrane transporter activity
BkAM31D_RS23260	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BkAM31D_RS23265	COG1737	Transcriptional regulator
BkAM31D_RS23270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BkAM31D_RS23275	COG0629	single-stranded DNA binding
BkAM31D_RS23280	COG0360	Binds together with S18 to 16S ribosomal RNA
BkAM31D_RS23285	COG0012	GTP binding
BkAM31D_RS23290	COG4481	Protein conserved in bacteria
BkAM31D_RS23295	COG3949	Membrane
BkAM31D_RS23315	COG1475	DNA binding
BkAM31D_RS23320	COG1192	Involved in chromosome partitioning
BkAM31D_RS23325	COG1475	DNA binding
BkAM31D_RS23330	COG0357	Ribosomal RNA small subunit methyltransferase G
BkAM31D_RS23335	COG0445	tRNA wobble uridine modification
BkAM31D_RS23340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BkAM31D_RS23345	COG1847	R3H domain protein
BkAM31D_RS23350	COG0706	membrane insertase activity
BkAM31D_RS23355	COG0594	ribonuclease P activity
BkAM31D_RS23360	COG0230	Belongs to the bacterial ribosomal protein bL34 family